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A Community of Exceptional Nurses
Back to AACN News Home
Jacqueline M. McGrath, RN, PhD, CCNS, NNP, has accepted a position as program director for the Neonatal Nurse Practitioner track at Arizona State University College of Nursing, Tempe. This new program has been funded for $569,000 by the Division of Health and Human Services for three years.
Terri Crowder, RN, BSN, CCRN, and Chris Ladoksy, RN, CCRN, have been promoted to team leader positions in the medical ICU at Mary Washington Hospital, Fredericksburg, Va.
Rika M. Felonia, RN, BSN, has been promoted to director of education at Lake Mead Hospital Medical Center, North Las Vegas, Nev. She has worked in the ICU for the past eight years.
June Howland-Gradman, RN, MS, MBA, received her her master's of business administration degree from Keller Graduate School of Management, Chicago, Ill. She is a past treasurer of AACN and a former member of the AACN Certification Corporation Board of Directors.
Pauline McGlashan, RN, MSN, CCRN, graduated from Barry University School of Nursing, Miami Shores, Fla., after completing the MSN-ARNP family care program. She was inducted into Sigma Theta Tau.
James D. Forrest, RN, BSN, received his bachelor of science in nursing degree from Mississippi University for Women, Columbus, Miss. In addition, Forrest, along with four other nurses, received the Baccalaureate Student Research Oral Presentation Award from the Zeta Rho Chapter of Sigma Theta Tau.
Sharon Melvin, RN, BSN, CCRN, received her bachelor of science in nursing degree from the University of New Mexico, Albuquerque. She was inducted into the Gamma Sigma Chapter of Sigma Theta Tau.
Debra Siela, RN, MN, DNSc, CCNS, CCRN, CS, RRT, received her doctor of science in nursing degree from Rush University, Chicago, Ill. She teaches at Ball State University, in Muncie, Ind.
Sonja D. Brune, RN, MSN, CCRN, CEN, CCNS, received her master of science in nursing degree from the University of Texas Health Science Center, San Antonio, Texas. She is a clinical nurse specialist who works as an advanced practice nurse at a private practice cardiology group in San Antonio. In addition, she is a member of Sigma Theta Tau and is chairperson of the American Heart Association Cardiovascular Nursing Committee in San Antonio.
Mary M. Canobbio, RN, MN, FAAN, was the author of the 7th edition of Patient Care Standards, as well as the 2nd edition of the Handbook of Patient Teaching. Both books are published by the Mosby Co., St. Louis, Mo.
Maureen Shawn Kennedy, RN, MA, was coauthor with Thelma M. Schorr, RN, BSN, FAAN, of 100 Years of American Nursing: Celebrating a Century of Caring, published by Lippincott Williams & Wilkins.
Diane Mick, RN, PhD, CCNS, has been appointed editor of the Critical Care Nursing Department for the American Thoracic Society's online journal club. She also was recently awarded $16,000 from the University of Pittsburgh Central Research Development Fund for a study titled "Response Shift in Aged Survivors of Critical Illness." This competitive grant was awarded by the University of Pittsburgh Central Research Development Fund.
Frank L. Cole, RN, PhD, CEN, CS, FNP, received the National Nurse Practitioner Outstanding Faculty Award for 2000 from the Nurse Practitioner Associates in Continuing Education in recognition of his efforts in education for emergency nurse practitioners, including developing the emergency nurse practitioner program at the University of Texas Health Science Center, Houston. Cole is associate professor of nursing, head of the emergency care division and director of emergency nurse practitioner education at the University of Texas Health Science Center at Houston, School of Nursing.
Dee Ann Day, RN, MSN, CCRN, CNS, ANP-S, was honored as the Metroversity Faculty of the Year for 2000 at Spalding University, Louisville, Ky. She was also nominated for the National League of Nursing Nurse of the Year. In addition, Day received the 2000 Kentucky Coalition of Nurse Practitioners & Midwives student scholarship and was the recipient of the Sigma Theta Tau Nursing Leadership Award.
Exemplifying the Value of Dignity
The critical care team at Mercy Hospital, Bakersfield, Calif., was selected to receive the 2000 Values in Action award for the Catholic Healthcare West Central California Region. This year's award focused on the core value of dignity. Members of the team included staff from Mercy Hospital's ICU and direct observation unit. In addition to nurses, the team is comprised of physicians and support staff providing auxiliary services.
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LORETTO - There's Quinnipiac, and then there's the rest of the Northeast Conference.
The Bobcats were a perfect 18-0 when the regular season ended last week, putting them a staggering five games ahead of the rest of the league.
They are the odds-on favorite to win the NEC championship, but seven other teams - including St. Francis - will make them earn it.
"I think we have as good of a chance as anyone in the league to beat them," St. Francis coach Joe Haigh said. "But they are a very good team. They've been amazingly consistent all year. I think we'd have a good shot against them."
St. Francis will have to get past Central Connecticut State first, as the fourth-seeded Red Flash (15-14, 10-8 NEC) host the fifth-seeded Blue Devils (16-13, 10-8) in today's quarterfinals at 3 p.m. at DeGol Arena.
The two teams protected their respective home floors and split this year's season series. St. Francis won, 67-62, on Feb. 7, and Central Connecticut snapped a seven-game losing streak to the Flash with a 76-71 win on the final day of the regular season.
But despite the recent loss, Haigh feels his team has a few advantages.
"The major advantage is playing them at home," he said. "Knowing that we're coming back home, knowing we should shoot the basketball a little bit better, we should get a little more a boost from our crowd."
It's a unique situation, but St. Francis is no stranger to opening the NEC playoffs with the team it concluded the regular season against.
The Red Flash beat Robert Morris in consecutive games in 2009 on their was to a title game appearance.
"From the scouting report part of it, it's a big advantage because we're playing [CCSU] right away," Haigh said, noting that most of the preparation was already done. "It's a quick turnaround."
St. Francis and Central Connecticut have had a handful of tough battles over the past few years, and if history is par for the course, Sunday's matchup will also have that championship-type feel.
"It's a tough matchup with Central because of their defensive philosophy and the way they play the game," Haigh said. "They are an extremely physical team. They play a tougher style than most of the teams in the league.
"A big difference with Central this year, for a team that's so physical defensively, they're so dangerous in transition. They're very disciplined in transition."
The Red Flash's Alli Williams comes into the game averaging 17.4 points (second in the NEC) and 10.8 rebounds (fourth) per game.
She and the Blue Devils' Jaclyn Babe were all-NEC and College Sports Madness first team selections. Williams also picked up the Player of the Year award from CSM.
"I think it's great for her," Haigh said of Williams. "It's great for the program to get the recognition. She's had an amazing season. I know she was in consideration for player of the year, and I have to believe she was one of the top three in the league.
"I've been saying it all year. The way that she has improved at the end of last season coming into this year, and the things she did to get ready to play this season - she really worked hard. And for working that hard, it's good to see it pay off for her and get results from it. We wouldn't be where we are without her."
Babe is fourth in the league in scoring (16.0). She averaged 27 points in two games against the Flash this season.
"Jackie Babe is the primary offensive threat," Haigh said. "She's a great player. She has improved from last year. You can tell she continues to work on her game as a fifth-year senior. She make open shots. She doesn't miss too many. She makes plays better than almost any kid in the league."
Should St. Francis win today, they'll more than likely have to play on the road on Wednesday, which is something that hasn't worked well lately for the Flash.
They won their first three NEC road games this season before dropping their final six.
"If I knew, or there was an answer to it, I'd fix that problem," Haigh said of his team's road woes. "But we have really stunk - we've been bad on the road. We've just had no intensity and no fire. Our starters have been really flat for whatever reason. I don't have an answer. It bothers me a lot.
"The Central Connecticut game is going to be a very tough one to get past. But if we get by them, we have to go on the road. Hopefully in a playoff atmosphere something sparks and we play a little better."
Playoff predictions
Quarterfinals - No. 1 Quinnipiac (27-2, 18-0) over No. 8 Bryant (12-17, 8-10); No. 7 St. Francis Brooklyn (11-18, 8-10) over No. 2 Sacred Heart (21-9, 13-5); No. 3 Monmouth (15-14, 12-6) over No. 6 Mount St. Mary's (14-15, 10-8); No. 4 St. Francis (15-14, 10-8) over No. 5 Central Connecticut (16-13, 10-8).
Semifinals - Quinnipiac over St. Francis Brooklyn; St. Francis over Monmouth.
Championship - Quinnipiac over St. Francis.

subset: commoncrawl


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Last edited by cori93437; 01-20-2012 at 04:23 PM.
You have your way. I have my way. As for the right way, the correct way, and the only way, it does not exist.
~Friedrich Nietzsche
And that's why I'm here eating HFLC Primal/Paleo.
I took Lugols as well as selenium and magnesium and my thyroid became swollen and bulgy. I read that was caused because the thyroid was trying to suck in as much iodine as possible. I dunno. I stopped taking it shortly after the swelling. It went down but it's not gone. I'm going to eventually go get my thyroid tested. I used to take Synthroid but stopped a couple of years ago. I have a thread about finding a doctor in odds and ends about that.
kiss = keep it simple, sister!
DUDE. My hands and feet are always cold! I'm even wearing fingerless gloves as I type this!
Can tincture of iodine be found anywhere? Any drug store? Or a naturopathic one?
Sometimes I get so confused around here...
I thought that going Paleo/PB was about getting the nutrition we need as naturally as possible. Why all the rush towards pills, tinctures, and such?
Seaweed/Kelp products are nutritious and have many benefits including iodine, other micro-nutrients, minerals... etc.
Why not try adding several servings a week to your diet... then seeing if you still need supplementation.
WHFoods: Sea vegetables
I supplement potassium orally as necessary, as well as consuming potassium rich foods. I need this because potassium depletion is a very significant side effect of a prescription medication I have to take as there is no alternative. Though I do hope that through Paleo/PB I will be able to get away from this medication.
I also take D3 because I have tested low for it. I hope to get away from this as well.
You have your way. I have my way. As for the right way, the correct way, and the only way, it does not exist.
~Friedrich Nietzsche
And that's why I'm here eating HFLC Primal/Paleo.
I'm with you, Cori. I hate taking supplements, but I think we all get a little lazy, and it's easy to pop a pill or two here or there.
Mark has even said a good quality multi-vitamin is a good idea.
I'm going to see how much I can get kelp chips for at a local Asian market. Hopefully they're not full of CRAP!
Don't think of the price (maybe $5-10 for a 50gm bag) as what you are purchasing... a Tbs dried will easily equal at least a half a cup of re-hydrated kelp. It quadruples in size!
It's really mild and goes well with most anything once yu get used to the texture, but my favorite is to toss it in some broth, and add shrimp sauteed in butter and garlic if it's a meal, sliced green onions on top... NOM!
You have your way. I have my way. As for the right way, the correct way, and the only way, it does not exist.
~Friedrich Nietzsche
And that's why I'm here eating HFLC Primal/Paleo.
Has anyone tried foraging for seaweed? A bag of Dulse costs a lot of money and there's a whole ocean of seaweed out there. I live on the coast in Southern California. I can take a walk on the beach every day. There's TONS of seaweed washed ashore all the time. I once had a Japanese exchange student living with me and she took a walk on the beach with me one day and pointed to all the different kinds of seaweed. That one's good, that one's really good. She even knew the names in Japanese for them all. You can't go wrong with kelp. It's all edible. The ocean is clean where I live. So I've been thinking about foraging my own seaweed. Has anyone tried this and had success?
Female, 5'3", 50, Max squat: 202.5lbs. Max deadlift: 225 x 3.
Have you checked out New Book on Hypothyroidism and Hashimoto's by Datis Kharrazian, DHSc, DC, MS ? That book will tell you which tests you need, as well as what lab ranges should be used to interpret the results.


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I don't have any friends
Does your life revolve around work and family commitments, with little or no chance to laugh with friends? Is your closest pal a tub of Ben & Jerry's ice-cream? If you've admitted to yourself "I feel unhappy because I don't have any friends", you need to examine why you feel that way – and what you can do about it.
Have you cut yourself off from friends because of your weight?
Those of you with a large amount of weight to lose may feel deeply unhappy about going out and socialising. Shauna Reid writes very movingly and honestly about this on www.dietgirl.org – saying how she worried about friends wanting to go for a walk. It's incredibly common for people to feel ostracised by their weight; if all your friends are slim, you may hate being the one who stands out in the crowd.
Unfortunately, cutting yourself off from friends can be very damaging to your health. Being bored and alone often leads to unhealthy snacking – I know that I, and many other successful dieters, had to ditch the mindset of solitary binge-eating: there's something guiltily exciting about crisps and chocolates scoffed in secret, and we may fool ourselves that if nobody sees us, the calories don't count…
Living as a social recluse is also bad for your mental wellbeing, especially if you're prone to mild depression, or if you're naturally shy.
Do you have friends, but lack time to see them?
When you look back to your school or university days, you were probably surrounded by friends. At school, you saw them every day in class or on the playground; at university, they lived in the same house or halls as you. The world of work can come as a shock after this: when I graduated and moved to London, I felt very lonely at first. If your friends have spread themselves around the country, it's difficult to find time to meet up.
Or perhaps you do have friends nearby, but you're too tired in the evenings to invite them over, and family commitments seem to eat up your weekends.
Often the biggest challenge is simply getting round to setting a time and place to meet up. When you're used to the spontaneous socialising of student life, the need for foreplanning as a working adult may pass you by. Grab your diary for April – have you got a free Saturday or Sunday? Why not call or email a friend today to invite them round for lunch, or to suggest going out for a drink?
Finding old friends
If you still feel that you don't have any friends, it's time to find some! That could mean getting back in touch with people you've lost contact with.
Old friends are easy to re-establish a connection with: just ring or email; don't feel shy about it, as they'll likely be delighted to hear from you and they'll want to get you caught up on all their news. If you don't have any details for them in your address book, try searching for them on popular social networking sites such as www.myspace.com, www.bebo.com or www.facebook.com – or just type their full name into your favourite search engine and see what comes up!
Once you've made contact, stay in touch. I find Facebook very useful for keeping track of all my friends – almost everyone I knew at university uses it, and it's an easy way to see what everyone's been up to. Email is also great, since it's instantaneous and free, but why not write a proper letter once in a while? I know how much it brightens up my day to have a handwritten card or note in the mail, amongst the usual junk and bills.
Where to make new friends
There are lots of reasons why you might want to be brave and forge some new relationships. Perhaps you've moved abroad and away from all your friends. Perhaps you're deliberately seeking to put the past behind you.
One of the easiest ways to meet new people is online. Join a web forum related to one of your interests or hobbies: you may want to "lurk" before joining to get a feel for the community there. I strongly recommend the friendly people at the Steve Pavlina forums — the forums are orientated around the idea of "growth" in your life, but these are subdivided into topics such as Health & Fitness, Business & Career, Technology, and so on. The users of Weight Loss Resources are also a very friendly and supportive bunch (you do have to pay to subscribe, but the site has a lot of valuable tools and information to help you meet your weight loss goals.)
Other ways that have worked for me in finding some great friends online are:
- Starting up my own blog (here!) and emailing fellow bloggers. (If you've got a blog, do email me – firstname.lastname@example.com – to let me know about it.)
- Playing online games. As a shy teenager – and then as a university student with too much time on my hands – I used to spend hours playing a textual fantasy roleplaying game online (yes, it was just as geeky as it sounds.) The friendships I formed through that have lasted over the years.
If you want to meet people in your local area, try joining a community group or a church. When I first moved to London, the only people I knew were colleagues and the members of my new church: I've always met with a warm welcome at the various churches I've been a member of during my life.
Joining a club or hobby-based group is also a brilliant way to get out and meet people who share your interests. I've been to some of the mid-week meetings of the East Dulwich Writers' Group, and it's been good to meet some fellow creative writers.
Find those friends now
Decide on some concrete actions that you'll take to get in touch with old schoolmates, to make time to see the pals who do live nearby, or to find some new friends. I tend to be a little introverted by nature, so I know this is one of the areas I need to make an effort in to. My actions for the next couple of weeks are:
- Send a message to my group of friends from university who correspond by email.
- Start the ball rolling to organise a big "meet up" in the summer with friends I've not seen for a while.
What are you going to do to ensure that, in a month or two, you can say "I feel happy because I'm surrounded by friends"?
(Image above by decadentyou)


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Probably surprising to many westerners is the large of amount of ancient myth that surrounds these beautiful fish in the Orient and their elevated status there. Generally known here as the brightly colored fish that are common in public ponds and fountains, carp (koi is Japanese for carp) can be found in colors that include white, yellow, gold, a deep orange, and some are even calico-colored. Particularly beautiful specimens have been known to fetch prices in excess of half-a-million dollars from private collectors who specialize in their breeding and showing. However, the koi is more than just a colorful and collectible fish. It is also one of the most popular and beautiful of Japanese tattoo symbols–a beauty which belies its symbolic meaning.
Although Chinese in origin, the carp is now widely celebrated in Japan, particularly for its manly qualities. It is said to climb waterfalls bravely, and, if caught, it lies upon the cutting board awaiting the knife without a quiver, not unlike a samurai (warrior) facing a sword. This theme dates back to ancient China, where a legend tells of how any koi that succeeded in climbing the falls at a point called Dragon Gate (on the Yellow River) would be transformed into a dragon. Based on that legend, it became a symbol of worldly aspiration and advancement. Eventually, the stoic fish came to be associated with so many masculine and positive qualities that it was appropriated for the annual Boys' Day Festival in Japan where even today colorful, streaming koi flags are traditionally displayed for each son in the family. In tattoo imagery, especially in combination with flowing water, it symbolizes much the same: courage, the ability to attain high goals, and overcoming life's difficulties.


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Laconia police were searching for the man who allegedly robbed two people at gunpoint on Sunday afternoon.
The victims told officers they gave Joshua McNeil, of Brockton, Mass., a ride, and while they were driving McNeil pulled out a handgun and demanded one man's wallet. The victims said McNeil hit the man with the gun, and ordered the second man out of the car.
Authorities said McNeil ran off, and advised anyone who comes in contact with him to contact Laconia police.


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Frosty and Joan Mitchell say 'Thank You' and 'Goodbye' to Grinnell
Former long time Grinnell residents, Joan and Frosty Mitchell, made their exit from Grinnell by providing the entrance to the remodeled and enlarged St. Francis Manor Health Care Center. The $10,000 gift is a thank you to the area citizens as the Mitchells begin their permanent residence in Stuart, Florida.
The Mitchells purchased radio station KGRN in 1959 and moved from Des Moines to Grinnell with their three small daughters, Mianne, Debra and Dorea in 1960. KGRN became the home office of Mitchell Broadcasting Company, which grew into several Midwestern AM and FM radio stations and ownership of the Iowa Hawkeye Sports Network.
The Mitchells have a long history of health care involvement in Grinnell. Frosty was instrumental in the merging of St. Francis Hospital and Community Hospitals into the building of Grinnell General Hospital.
In the late 1960's, St. Francis Hospital was located on the present St. Francis Manor site and Community Hospital was on the site of what is now Grinnell Regional Medical Center.
After this merger of hospitals, Frosty was chairman of the fund raising drive to build Grinnell General Hospital. After the drive's success and Grinnell General Hospital was constructed, he served as Chairman of the Board, and the new facility was opened, and the St. Francis property was transformed into a nursing home facility.
The Mitchells and their daughters funded "The Mitchell Meditation Room" in the most recent expansion of Grinnell Regional Medical Center. The room known as the "Grace Place" serves the hospital patients, employees and visitors as a chapel.
Joan was an early member of the St. Francis Manor board serving for 10 years from October 1983 to October 1993 and during that time was President from 1991 to 1993. It was during these years that the board of directors worked with Executive Administrator Dion Schrack to develop the Seeland Park retirement community.
In describing her service at St. Francis, Joan Mitchell said, "Of all the state-wide and local boards and commissions that I have been privileged to serve on, St. Francis Manor touched my heart the most. Those early years of financial and facility struggles were difficult, but we were working with a young, energetic and determined executive administrator [Dion Schrack] and the other outstanding individuals on the board who made our growth possible, to today looking at the expansion and state of the art facility, that soon will be the envy of the nursing home industry in Iowa. I am grateful and blessed to have been a small part."
When asked for a comment on their gift, Frosty Mitchell said, "I was always so proud of Joan's participation at St. Francis. Grinnell has been good to us and our family. It was a great place to be in business and to raise and educate our children, and call home for over fifty years. This gift is another gesture of our belief in helping financially with healthcare, education and churches while in Grinnell. As we leave our legacy, it is best stated in the words that will be in the new entry way of St. Francis Manor: 'Through these doors, pass the world's greatest people… Grinnellians and their friends."


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Brothers Pawn Shop telephone number is (479) 675-4231.
Telefax: No fax number available
Website: No web address available
Biz owner? Moderate reviews or edit listing.
Search entire category for Resale Shops
Resale or Charity Shops, in Booneville, sell used, passed-down, or second-hand products at very low prices to customers. However, the items are first reviewed for damages before they are displayed for sale. The items may range from clothings, books, toys, furniture pieces to even automobiles.
PSEG Long Island Helps Customers Go Green and Save Green
Energy Efficiency Programs Save Customers Millions of Dollars (Long Island, NY) PSEG Long Island announced today that customers participating in energy efficiency programs in 2015 will save more than $60 million and 307,582,000 kilowatt hours (kWh) per year. The amount of energy saved is good for the environment, too, as it results in the elimination of the carbon dioxide..


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In Brief: Frontier Park to screen 'Karate Kid' tonight
German festival starts Saturday
The annual German Heritage Festival takes place Saturday, 11 a.m. to 8 p.m., and Sunday, 11 a.m. to 6:30 p.m., at St. Nick's Grove, 5131 Old French Road. Enjoy German music, food, music and dancing, plus a petting zoo and other activities for kids.
Cost: $5; children younger than 12, free.
Info: Visit www.dank-erie.org or call 456-9599.
Fundraiser to aid region's veterans
The '80s & '90s End of Summer BOG Bash on Saturday, 1 to 8 p.m., at Skibinski Picnic Grove, 5571 Henderson Road, includes music, food, beer, 50/50s and more. Proceeds will benefit Boots on the Ground, which builds awareness about veterans' issues.
Cost: $10
Info: Visit www.hmwbootsonground.com, 920-3600.
Enjoy final bike night
Don't miss the last bike night of the summer tonight, 6 to 10 p.m., along State Street from Fourth to 12th streets.
Cost: Free
Info: Visit www.eriedowntown.com.
See 'Karate Kid' tonight at Frontier
Watch "Karate Kid" outdoors, starting at dusk, at Frontier Park. Bring lawn chairs, blankets and snacks.
Cost: Free
Info: Call 453-5323.
Wattsburg Fair ends Saturday
The Wattsburg-Erie County Fair, with rides, midway games, entertainment, truck and tractor pulls, animal exhibits and more, continues today and Saturday, at the Wattsburg-Erie County Fairgrounds, Wattsburg.
Cost: Adults, $4; children 6 and younger, free; Ride A Rama, $20
Info: Visit www.wattsburgeriecountyfair.com.
Get book bargains at Blasco Library
The Blasco Library holds its end-of-summer mystery and fiction book sale today, 10 a.m. to 5 p.m. and Saturday, 9 a.m. to 4 p.m. Find more than 4,000 gently used books available for purchase.
Info: 454-6770.
Find stamps, coins at show Saturday
The Erie Stamp and Coin Show is set for Saturday, 10 a.m. to 4 p.m., at the Quality Inn, 8040 Perry Highway.
Cost: Free admission
Info: Call 833-3733.
Drama continues at All An Act
"Twelve Angry Men" continues tonight and Saturday, 7:30 p.m., and Sunday, 3 p.m., at All An Act Theatre Productions, 652 W. 17th St.
Cost: Adults, $12; senior citizens and students, $8
Info: Call 450-8553 or 449-6554 or visit www.allanact.net.
Enjoy art, music at Bayfront Gallery
Art Meets Rock at the Dock is an exhibition of vintage rock posters and rare art posters, Sunday, noon to 5 p.m., with music by Stonehaven, from 1 to 3 p.m., at the Bayfront Gallery, 17 E. Dobbins Landing.
Cost: Free
Info: Send e-mail to email@example.com.


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It's a quick and easy way to stay in touch and hear the latest news and announcements! Just fill out the short form below.
Welcome to Arts Together, where individual creative strengths are nurtured in a diverse, inclusive and collaborative environment!
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It's a great way to stay informed!
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Click here for more details.
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Popularity is the one insult I have never suffered.
– Oscar Wilde
Popularity is the one insult I have never suffered.
– Oscar Wilde
For all the writing I do about social skydiving, the vast majority of my interactions with women don't go any further than our initial conversation. In fact, sometimes they barely get beyond "Hi". I've talked to hundreds of women in the past year, but I've gone on dates with a mere fraction of those, probably around three to five percent. Sometimes it's because I'm not interested. The other 90% of the time it's because she's not interested.
Exercising choice in the women you bring into your life is all about being willing to get blown out and fail your way forward. An important tool with which to navigate yourself through the battlefield is social polarity.
Social polarity is the idea that no matter what you do, what you say, what you look like, how you act, how you dress, or what your opinions are, some people will like you and some won't. Some guys will think you're cool, some women will think you're absolutely magnetic, and others will try to tool you and make you go away as quickly as possible. No matter how hard you try, there is no way to avoid the world around you being divided into the lovers and the haters. This idea applies as much to men as to women, and to interactions that are either purely platonic or more sexual in nature.
The implications of social polarity are extremely liberating. Knowing that, no matter what, I'm guaranteed to be liked by some and disliked by others has freed me up to be totally authentic. This has resulted in a tectonic shift in how I relate to others. Instead of trying to "get a good reaction", I'm concerned only with radiating my personality and focussing my attention on only those who are a strong vibrational match.
(Note: As you read what follows, try not to get to hung up by the specific terms used. I'm just describing a model of reality that works for me in meeting people, and I find these terms useful in capturing the key concepts of this model.)
Social polarity can be measured along four vectors:
Each of these parameters is a knob that you can adjust to modify your social energy signature, and thus change where the line is drawn between those who align with you and those that don't. The key here is to understand that social polarization is a property of the energy exchanged, not the words exchanged.
Guys tend to polarize with other guys primarily along the mental vector, and secondarily the emotional one. If you're at a party and happen to bump into a fellow Ruby on Rails geek, chances are you're going to hit it off pretty well, platonically speaking.
Women tend to polarize with other women first emotionally, then mentally. While both men and women are emotional creatures, women tend to exhibit a much wider range of emotions than men and tend to express those emotions more openly to their friends and lovers.
Platonically, a guy will tend to polarize with a girl either physically, emotionally, or mentally and the level on which each person resonates with the other may be totally different. A common example is the guy that resonates with the girl physically (read: he wants to have sex with her), while she resonates with him emotionally (read: he is her emotional tampon).
Finally, guys will tend to polarize sexually with girls along the emotional and physical vectors, with the mental vector being a distant third.
There are two fundamental types of social polarity: natural and unnatural. Natural polarity results from having a physical, mental, emotional, and spiritual profile that is consistent with itself. Among other things, it means that the way you think is the way you act, that you accurately express the way you feel, and that there's a general balance between your spiritual belief system and the physical, emotional, and intellectual expression of those beliefs.
Unnatural polarity occurs when one or more of these vectors fall out of alignment with the others. Instead of acting the way you think, you may suppress your true intentions and take this out in other ways like overeating, drinking heavily, or through a wide range of undesirable emotional responses. It may also mean putting up a front instead of expressing yourself honestly. What you see isn't really what you get.
Your social energy signature (SES) represents your unique physical, mental, emotional, and spiritual fingerprint in a given social context. Context is an important part of your SES because different social situations will emphasize different aspects of your SES, affect how it gets interpreted by others, and may even redefine your SES, at least in part.
For example, your SES at a Thanksgiving dinner with the family will likely be different from when you're out drinking at a pub with your coworkers. In some social contexts you may be seen as high status and/or have a lot of social proof where in others you might be a perfect stranger. And the social dynamics will be fundamentally different if you're surrounded primarily by guys, primarily by girls, or by some mixture of both.
So how can you use your knowledge of social polarity and social energy signatures to meet people?
For both men and women, social polarity has many implications for how you interact with the world as a social animal. I'm going to concentrate on what this means for the guy who wants to improve his success with women, since that's the context in which I have the most experience applying these concepts.
When it comes to approaching women, you don't need pickup lines. Social polarization implies that our alignment with others happens along energetic lines; the words don't matter. The only purpose of your "opener" is to initiate the flow of energy. In my experience, guys who focus too much on specific lines often just use that as an excuse, so that when they get blown out they can blame it on the line they used, when really the rejection happened at a much more fundamental, energetic level.
Instead of trying to "get a good reaction" from women, focus on becoming a polarity detector. A great Poker player spends the vast majority of his time folding, and a guy who gets the kind of women he wants spends most of his time getting rejected. The only way to avoid rejection is to avoid talking to women.
Beyond just approaching them, you shouldn't actually "try" to get women to like you at all. The most important thing is to express yourself as authentically as possible and leave the rest to polarity to determine if she's a good fit for you. Sure, you can change your social energy signature "on the fly" and thus change the way you polarize with a girl (though she still might not like you), but when you do gravitate back to your natural polarity, you might end up repelling her anyway, so there's no point faking it to begin with.
It's important to not let blowouts faze you, or at least to minimize their impact on your emotions. Rejection and full-on blowouts are a fundamental part of the social polarity model, and are merely the sign of a polarity conflict. This is where the spiritual vector comes into play. Your ability to, at least conceptually, step outside of your body and mind and observe your physical, mental, and emotional states as an impartial spectator is crucial to becoming the "nuclear unreactor" when faced with negative social inputs.
Social polarity is a powerful tool for navigating yourself through social interactions. It's a model that emphasizes that our alignment with other people happens primarily along energetic lines, rather than by carefully crafted conversation. Realizing that there is absolutely no way you can avoid having some people like you and some not frees you up to express yourself truthfully and focus your attention on only those who are a good vibrational match.
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very nice article man…. keep posting
I like the thought of your article. I really hate myself when I try to change my personality just so someone who doesn't even matter that much to me will like me. And when that doesn't work, I get depressed to a point that I question what kind of person I really am.
awesome, my brother is always just a jerk and his friends to so i hope this will work! Thanks
nice one dude
Great. I tried this and I got six new friends in one day!
This is a great article. Thanks for sharing, it gives me a logical framework to think about social interactions.
Reminds me of the Godfather "It's not personal. It's just business"
When you think about the many ways in which women size up men who are interested in them(and vice versa), from physical looks, to money, etc. It's really a series of unknowable trivial cues, idiosyncrasies and mood of that moment that may decide whether people accept us or reject us.
If someone's having a bad day, I don't take their negative comments to heart. If we are rejected in our romantic pursuits, why should I view it any differently?
i don't just know the people i like don't always like me and i don't no what to do.
Another article that reminds me I have no chance of ever meeting women. I'm going to be alone for the rest of my life, I just know it. I don't have what it takes to meet women, I've tried in the past and all I ever get is rejection after rejection. I've also lost all my friends, they all moved on with their lives because they have been able to meet women and gone on to various relationships and great careers. They're not waiting around for me because I'm socially awkward, and they have invested no patience in helping me out. They think I'm not even worth it. No one has ever shown any concern for the emotional damage they have done to me. They have all left me behind because I can't meet anyone. I have no one, I'm stuck in my parents house watching life pass me by. Because I don't have what it takes to attract anyone.
This is a great article!
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All roads might not lead to State College, but enough big-time prospects seem to be making their way there that Penn State football fans are feeling it is getting closer to Christmas than Easter.
"It's not exactly something that's really new,'' said Cory James, who follows Penn State recruiting for Scout.com, of junior days. "Where is new is they seem to be getting kids to come in from farther away places. This time of year, you can't take an official visit which is paid for by the school, so you have to get guys to spend their own money to get there, and there's some kids coming up from Georgia and Florida.''
With probably around 10 more scholarships available for its 2012 recruiting class than 2011, Penn State has been much more aggressive in its early recruiting. Instead of going for more intimate one- or-two-player visit weekends, the Nittany Lions are entertaining a plethora of prospects in the weeks leading up to Blue-White weekend.
Things began in earnest last weekend, as Bishop McDevitt all-everything defensive end Noah Spence and Ohio offensive lineman Anthony Stanko were among a small group in University Park on Saturday. During his visit, Stanko became the first commitment in a class expected to eventually number in the low 20s.
"I just wanted to reacquaint myself with the coaches and players,'' said Spence, a five-star talent with 30 scholarship offers who made the trip with teammate Brock Dean. "It was nice. It was very nice.''
This weekend's list of probable/potential visitors numbers around 20, and, as James noted, includes several players from areas not usually associated with attracting unofficial visitors to Penn State. Among them is blue-chip tight end Kent Taylor from Land O'Lakes High School and Nick Tompkins, a running back from Brookville High School in Snellville, Ga.
"Taylor is coming up with his family from Florida,'' James said of the 6-foot-5, 220-pounder who told 247sports.com that he was zeroing in on a 10-team list that included Penn State, Notre Dame, Florida, Florida State, Miami, Alabama and LSU. "That will be an important guy for them.''
Also on the list are Michigan defensive tackle Matt Godin and the Massachusetts trio of defensive back Armani Reeves, linebacker Camren Williams and receiver Canaan Severin. Linemen J.J. Denman and Chris Muller, tight ends J.P. Holtz and Brent Wilkerson, running back Drew Harris, wideout Eugene Lewis, safety Demetrious Cox, defensive tackle Julian Pinnix-Odrick and athlete Devin Fuller are anticipated to come in from the Nittany Lions more fertile recruiting grounds of Pennsylvania, Maryland and New Jersey.
Harris, Lewis, Denman and Reeves already have drawn four-star rankings from Scout.com.
"Camren Williams and Armani Reeves will be two pretty big athletes from up in that area which doesn't usually have a lot of talent, but it's similar to Khairi Fortt and Silas Redd from Connecticut. It's not a big-time talent area normally, but, this year, it looks pretty good,'' James said.
In the coming weeks, players like Illinois defensive tackle Tommy Schutt - like Taylor, a Nittany Lion fan growing up - Detroit corner Terry Richardson, Bloomsburg quarterback Blake Rankin and Pittsburgh offensive lineman Adam Bisnowaty are expected to make the trek to Happy Valley. That list will probably grow as other prospects iron out spring visit plans to other schools, as well.
It will all culminate with the Blue-White Game on April 16. BlueWhite Illustrated.com is reporting that Virginia defensive tackle Korren Kirven will be on hand for that along with quarterback prospects Ian Fisher of Maryland and Brendan Nosovitch of Allentown, while Spence, Stanko, Rankin and Dean will make return visits.
Getting Spence to make two trips in a month - especially considering he's already been to Penn State several times - is considered something of a coup for the Nittany Lions.
"He seems to really like [Nittany Lion defensive line coach] Larry Johnson and Penn State,'' James said. "I was really surprised that he was coming back for the Blue-White Game. On paper, he's going to look like he's a pretty good Penn State lean. I thought he might be one of those guys who kept it a little closer to the vest.
"That [getting Spence to visit for the Blue-White Game] would be big for Penn State, because a lot of these spring games are scheduled for the same day, so you kind of have to choose one.''
Spence confirmed his intentions to return to Penn State for the spring game Tuesday night. The Nittany Lions will still have their work cut out to land him; among his approximately 30 scholarship offers are those from Miami, Florida, USC, Georgia, Tennessee and Notre Dame. He has no timetable to narrow his list.
Spence said he is thinking of visiting Michigan and making a southern swing to South Carolina, Georgia and Florida in the coming weeks. So, he'll have a lot on his plate.
"I try to make time for myself,'' Spence said. "I still try to stay humble. I feel blessed by all of this.''
James felt Stanko, the nearly-300-pound guard/tackle from Howland, Ohio, got Penn State off to a good recruiting start.
"Not only is he a good lineman, but he was an Ohio State fan. He gives them someone in Ohio who can get in kids' ears,'' James said. "I know Penn State is looking at William Mahone, he's a running back and a safety. I know he's been talking to Stanko. They usually don't do that well in Ohio, so it was pretty big for that reason.''
James isn't anticipating the floodgates to open with verbal commitments between now and the Blue-White Game, but he thinks a couple of players could make pledges in that time frame or soon after.
"Eugene Lewis has been high on Penn State. It wouldn't surprise me if he went up at any time and committed,'' James said. "Tommy Schutt's really high on Penn State. I know he's looking at making an early decision. I don't know if it will be by then, but maybe a month or two afterward is possible. You won't see more than four or five at the maximum.''


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Arizona State University in Arizona
|Open until filled
|Date Posted
|August 27, 2014
|Non tenure track
|Not specified
|Employment Type
COLLEGE: W.P.CareySchool of Business
DEPARTMENT: School ofAccountancy
TITLE: Clinical Assistant, Clinical Associate, or Clinical Professor
CATEGORY: Non Tenure Track Faculty
Academic Appointment
Full-time, non-tenure-track faculty holding the rank of Clinical Assistant, Clinical Associate, or Clinical Professor in the School of Accountancy in the W. P. Carey School of Business.
The candidate must contribute to the School of Accountancys mission primarily in the areas of teaching, curriculum development, and service. The candidate must be able to deliver excellent instruction and to contribute to curriculum development at the undergraduate and masters levels.
A doctorate in business administration or a closely related field; AACSB faculty accreditation status based on AACSB criteria as interpreted for the W. P. Carey mission.
Potential for or demonstrated excellence in teaching and curriculum development
Potential for or demonstrated ability to integrate accounting research into the curriculum;
A doctorate in business administration or a closely related field from an AACSB accredited business school;
A recent record of publications in peer reviewed journals.
The initial application deadline is October 30, 2014 if not filled, then every two weeks thereafter until search is closed. Subsequent application deadlines which fall on a University holiday will default to the end of the next business day. Formal application may be accomplished through submission of a current vita in pdf format and evidence of teaching competency to email@example.com Please note on your application that you are applying for job search #10873. A background check is required prior to employment.
The School of Accountancy (http://wpcarey.asu.edu/acc/) delivers degree programs at the B.S., M.S. and Ph.D. levels. The schools full-time faculty consists of four professors, four associate professors, ten assistant professors, three clinical faculty, one professor of practice, and nine lecturers. The W. P. Carey School of Business (http://wpcarey.asu.edu/) is one of the largest business schools in the United States with more than 150 faculty, 1,000 graduate, and 2,600 upper-division undergraduate students. The school is ranked 28th nationally for its undergraduate programs and 27th for the W. P. Carey MBA.
ArizonaStateUniversitys (http://www.asu.edu)Tempecampus is located in the heart ofTempewhere 50,000 students are enrolled in daytime and evening classes. The university is recognized nationally as a foremost research institution offering excellent undergraduate and graduate education and nationally-ranked athletic programs as well as a full array of cultural activities. ASUs Tempe campus offers 87 bachelors, 95 masters, 48 doctoral or terminal degree programs, and one law degree program.
Arizona State University is an Affirmative Action / Equal Opportunity Employer
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text:
The Essential Mass Effect 3 Question: Who's Your Shepard?
(XBOX 360, PS3, PC, Wii U)
The battle against the Reapers is ultimately less important to me than the outcome of my heroine's tale.
I'll be curious to see how decisions like the Rachni crisis play into Mass Effect 3's outcome. Clearly it'll be of some relevance; BioWare conspicuously included it as one of a handful of player decisions in the PS3 motion comic that prefaced Mass Effect 2, yet its only relevance to that game was an emissary of the Rachni who thanked you for your mercy (if you were in fact merciful; the discovery that my less compassionate coworkers didn't meet that character was my first realization that BioWare was serious about carrying decisions across the series in ways both large and small). Likewise, Yukiko Shepard sacrificed a fleet of human warships to protect the bigoted Council, and she refused to give essential Reaper technology to Cerberus (who are just as racist as the Council, though in reverse).
You see, when faced with these political matters, Yukiko is prudent, even if it means putting up with infuriating prejudice. The galaxy's ruling council of aliens may be a sneering lot of anti-human racists, but she saved their hides during the attack on the Citadel anyway. Tempting as it might have been to put them in their place, Yukiko subscribes to the belief that diversity is ultimately in everyone's best interests. Assuming there's a happy ending to be found at the end of Mass Effect 3, it's bound to be happiest if humanity isn't remembered as a bunch of priggish survivalists who left everyone else to die.
Will there be a happy ending, though? Probably, though I do worry that Yukiko Shepard's selfless approach to the fight against the Reapers is destined to end in a noble self-sacrifice. And come to that, she'll probably take the fall for everyone else, because that's just the kind of lady she is. That's why I like her: My Shepard doesn't always make the easy choices (even if Mass Effect does tend to dish out a bit more in the way of experience points for playing nice), and they're definitely not the satisfying choices when the recipient of her largess would be more fittingly rewarded with a punch to the mouth. But she wouldn't be a hero if she played it any other way. More to the point, she wouldn't be my hero.
When I see BioWare's "official" Shepard, it's always slightly jarring; he doesn't look anything at all like Yukiko; neither, for that matter, does the (almost) contentious female Shepard that the company belatedly trotted out to promote the special edition of Mass Effect 3. When I see my coworkers' Shepards sporting their unfamiliar appearances, wearing their unfamiliar armor, employing their unfamiliar combat tactics, I'm always taken aback.
True, the Mass Effect games tell a fairly trite science fiction tale with dialogue that ranges from sublime to senseless, and they're still struggling to balance depth of content with usable interface design. Yet I find myself curiously attached to the very specific Commander Shepard with whom I've traveled the galaxy and fought impossible threats over the past two games -- attached to the point that I've been unable to go back into Mass Effect 2 in order to right various imperfections in my playthrough. I'm sure Yukiko's tale would turn out better if I were to undo her romance with Garrus -- there's a fairly old-fashioned morality lurking beneath the series' surface that's likely to reward faithfulness to Yukiko's first lover. I also suspect that Mass Effect 3's story would be far more hilarious if the sardonic Salarian scientist Mordin hadn't died in our final escape from the Reapers' lair. But these are the decisions that Yukiko made, and we'll both have to live with them, even if it means I don't experience the "ideal" playthrough of Mass Effect 3.
I always find myself bemused by the complaints that accompany news of any possible change BioWare may be imposing on the series' design and mechanics for Mass Effect 3. Shooter or turn-based RPG; in-depth leveling or simplified skill system: I don't especially mind either way. Those aren't the reason I play Mass Effect. As long as the third game brings a satisfying conclusion to this journey Yukiko and I embarked upon more than four years ago -- as long as the outcome of her tale properly reflects the choices we've made -- I'm not especially concerned with how I get there. BioWare has achieved something remarkable with Commander Shepard by letting me define the character as I see fit, then carrying those decisions across three separate games. My connection to and investment in the heroine I've shaped with my actions makes Mass Effect 3 the first game in a decade for which I genuinely fear spoilers. But then, no one else really could spoil the story; after all, they don't know my Shepard.
See all Mass Effect 3 Previews >
Comments (38)
PC GamesPosted: Oct 24, 2012 12:00AM PST by riley19901026
Gaming news. Videos. Gameplay
why?Posted: Apr 21, 2012 12:00AM PST by Clandestino
why is this article still one of the top 5 articles that show up when you're on the PC section of the site? i thought it was firmly established that whoever your shepard is, it doesn't matter, because you can only get 3 endings and the only difference between them was the color. in fact, i think this site may have even published an article or two about that...
4 Endings BitchPosted: Jul 28, 2012 12:00AM PST by Incredinic
Excuse me sir I beleive you can acheive a fourth ending by shooting The Child and refusing to save the world.
My ShepardPosted: Jan 18, 2012 12:00AM PST by Apollo_Helios
will forever be in the limbo of post ME2 save. Not buying ME3, EA fucked it up too hard. Online pass, bullshit multiplayer, forced Origin install, so on and so forth.
Here's to you Jimi Shepard, I wish I could see how your story ends.
Yours is not the only Yukiko Shepard.Posted: Jan 17, 2012 12:00AM PST by thepayne78
Your Shepard can't be Yukiko sheppard mine is ;). Glad to see I am not the only who has a Shepard named Yukiko.
My Shepard...Posted: Jan 16, 2012 12:00AM PST by GiffTor
I've played a lot (:slightly disturbing amount) of ME and ME2 and when I realized how close the final entry in the series was, I started a final playthrough of ME2...just so that I could have my "perfect" (read: exactly the Shepard I want him to be) for ME3. The only thing I haven't done is play as a female Shepard, despite the fact that Jennifer Hale gets such praise for her voicework. Unfortunately...but "my" Shepard is a dude.
ah...Posted: Jan 16, 2012 12:00AM PST by Sabotender
that video reminds me of when 1up had quality video segments
FemShep is my preferred choicePosted: Jan 16, 2012 12:00AM PST by Sam_Aran
Even after I'm finished with ME3 I'm going to go back and start it over to get different results. Unfortunately, thanks to Microsoft, I cant play the first ME since I own a ps3, but I do have the motion comic DLC. Screw YOU Microsoft!!
make money onlinePosted: Jan 16, 2012 12:00AM PST by Sophie_Williams
my co-worker's half-sister makes $84 hourly on the computer. She has been fired for 10 months but last month her paycheck was $8978 just working on the computer for a few hours. Read more on this web site... LazyCash1[dot]co
one of these daysPosted: Jan 16, 2012 12:00AM PST by SuperSledge
I'll create an alternate shepherd but for now I've just been going with the soldier shepherd on the box
You play like I playPosted: Jan 15, 2012 12:00AM PST by spiclicous
The only difference is I made sure everyone lived at the end of ME2... and I'm a male Shepard. If I were to write a piece like this it would have been pretty damn similar (I too am curious as to what happens with the Rachni). On the other hand, I sometimes find issues with just how different things can be. On one hand it takes a lot of explaining to share what you've gone through in the ME series compared to your friends. Sometimes I think it would be nice just to talk with a buddy and both love a part that happened similarily. But then I realize that we spend hours comparing and contrasting playthroughs just because we love that our Shepards and actions are so different, and our stories are unique -- even if we both think we have "the correct" Shepard. In short: the Mass Effect series is fantastic.
I play Dirty HarrietPosted: Jan 13, 2012 12:00AM PST by Ersanven
Because I'm just that unoriginal. My Shepard is a Paragon with a hard edge. A nightmare to her enemies and a gentle hand to her friends. She's primarily diplomatic but is not afraid to shed blood if need be. She makes good on her threats as she is honest and forward.
Your Shep sounds boring.Posted: Jan 13, 2012 12:00AM PST by solidfenix
Theres only one Shepard and thats Jack Shepard. A Badass, take no prisoner, hope you're not standing in front of a large window with a long fall renagade. Who also has a soft spot for fiesty brunettes. (Can't wait to see that cat fight in ME3) Killed the Rachni and sacrificed the Council but told the Illusive man to shove it cause he's Alliance through and through.
why couldn't they have chosen...Posted: Jan 13, 2012 12:00AM PST by jediassassin420
David Hayter A.K.A Solid Snake. only he can prevent forest fires...oh and the complete anihalation of the known universe.
My Shepard:Posted: Jan 13, 2012 12:00AM PST by awwnuts07
Name: Kira Shepard
Sex: F
Alignment/Class: Paragon Infiltrator
Preferred method of engagement: 1 shot 1 kill from a cloaked position with an M-98 Widow.
She's the last thing the bad guys never see.
Mine's name is Geoffrey.Posted: Jan 13, 2012 12:00AM PST by Sabrewing
I'll admit, I have him as close to Paragon as I can play him -- I didn't even take Renegade interrupts when they would make an ensuing battle easier -- although I've made a few "questionable" choices. I allowed Wrex to collect his bounty on Fist (the man has no redeeming qualities whatsoever, just like Kraze in Suikoden 1, who I also always execute), and with the ambiguous missile-targeted-colony mission in ME2, I opted to save the industrial section over the colonists; I don't know whether that colony remaining viable will be an asset against the Reapers, but I'd like to think so.
Also, since Ash rejected me, I went ahead and pursued a romance with Tali. We shall see what comes of that.
You can either fight at my side or get crushed under my heelPosted: Jan 13, 2012 12:00AM PST by ilikecheese
But you will not stand in my way
Fulfilling a hope...Posted: Jan 13, 2012 12:00AM PST by Luminari
Well, said Jeremy. I do recognize the "trite" aspects and balance between play and control, etc. But the ability to carry decisions and consequences between games and a consistency of character and interactions unique to my Play exprience...that at least give the illusion of "unique" and not a decision-tree or map I can readly see between the seams...has been a hope and dream for "video game" series for some time. It was an ambitous goal that has mostly worked out rather successfully. But was it luck...or serendipity? I really hope to have the same kind of experience over another console generation (or even PC) more than once. I don't care about setting or world...but the satisfying feeling that the story matters because of MY decisions. Will we see another BioWare "trilogy" or other series in the future? I hope so...I Don't need to have a Mass Effect 4...but I do want to explore the life an consequence of another "Shephard." Three different versions on three different platforms...but all feel genuine. I know it's not easy and the stats show the Female Shephard players are a minority...but I really appreciate a "blank" character I "make"...with gender, history, personality, appearance...if I choose a female, she can be dignified and run around the world not Forced to wear a bikini...unless I choose I guess. And if I make it a male, buff character...he can be as empathetic, intellectual, and patient as I want...or make him headbut someone and deal with the consequences. Onward and Upward I hope to BioWare and anyone else pushing the RPG genre for interactive media.
Great article, JeremyPosted: Jan 13, 2012 12:00AM PST by Arcade_Wiz
I agree with your last sentence. To me, Mass Effect is about shaping my Shepard's tale within the limitations of the game's story-branching mechanics.
That said, I am happy to hear there will be a bit more "RPG-ness" in ME3 than there was in ME2. I would still probably enjoy it if there wasn't, though. I was very happy with ME2, aside from the final boss. It didn't break the universe or make me not care about what happens next, but I did roll my eyes a little.
I think the original ME had a better "plot," but ME2 had better character development and storytelling methods for each mission. Here's hoping ME3 takes influence from the best aspects of both previous games.
I also have a strong connection with my ShepardPosted: Jan 12, 2012 12:00AM PST by Hedgepig
Sarah Shepard, who's neither paragon nor renegade but somewhere in between.
So much so that I find it difficult to make different decisions on additional playthroughs. I just know that's not what happens in my story, so I can't bring myself to do it.
I tried making a different character of a different class, that lasted all of 10 minutes before I quit.
WellPosted: Jan 12, 2012 12:00AM PST by sepewrath
I'm not bothered by other Shepard's or the marketing Shepard(though that Femshep vote, then mulligan was incredibly stupid) My Shepard is pretty similar to the Major A.K.A Motoko Kusanagi of Ghost in the Shell fame. A inflitrator, who spends a lot time in camo(that just worked out so well in ME2) mostly paragon but with an edge to her and of course fittingly, with the glorious pipes of Jennifer Hale. She'll save someone when the option exist, but she wont risk her team or the galaxy for her own personal spiritual well being i.e. being a bleeding heart
Oh and FYI Parish you spelled Kaidan wrong, the fanboys and girls would tear you apart on BSN for such a vile trangression
I remember David Ellis.Posted: Jan 12, 2012 12:00AM PST by SamuraiTerry
Good times.
All about the FemShepPosted: Jan 12, 2012 12:00AM PST by learningKnight
I concur with Jeremy's notion that Mass Effect is a much better game with a female Shepard. Jennifer Hale's take on the character (i've long been a fan of hers) constitutes one of my favorite all-time video game performances, adding much-needed depth and nuance. Plus, there is something more compelling to me about a lady Space Ranger; male Shepard seems too much in line with the square-jawed macho-man supersoldier that has become one of gaming's biggest clichés. Adding a little femininity to such a tough-as-nails badass gives Shepard just enough vulnerability to make her a real, three-dimensional character of the sort that is all to rare in gaming. If you've been playing Mass Effect with a male Shepard, you've been missing out on one of Mass Effect's biggest strengths.
Couldn't agree more.Posted: Jan 12, 2012 12:00AM PST by ThuperThathy
Also, default male Shepard looks like a pedophile. I don't know why?
about maleShepPosted: Jan 12, 2012 12:00AM PST by great_cake_bat8
Mark Meer is pretty fun in side character roles (he did voice the crazed "biotic god" volus and other random roles). oddly enough he resembles carth from KOTOR more than default shepard
Strangely.....Posted: Jan 12, 2012 12:00AM PST by Redmagpie93
My FemShep looks oddly like an older, wiser version of the 'official' FemShep android that they have created ;p
I just...Posted: Jan 13, 2012 12:00AM PST by GoKickyFastOK
Didn't want to look at a guy's ass for the countless hours I put into the game.
I agree that her voice acting has really helped to keep me invested in the series and story.
something that kind of killed my enjoyment of replaying Mass 2Posted: Jan 12, 2012 12:00AM PST by great_cake_bat8
your dialouge skill was dependent on how many times you picked a paragon or renegade response, which ment that if you wanted to use the special dialouge options that would result in the best quest ending you would have to escew role playing and just pick one type of respose to gain points. Granted I still made my first playthrough without min/maxing the dialouge stat but if it remains in Mass 3 it would be tempting to focus on gaining paragon/renegade points to increase my dialouge options.
on an unrelated note I would so play a mass effect space sim game (there's not even a mass effect freespace mod).
Same thing happened me...Posted: Jan 12, 2012 12:00AM PST by Redmagpie93
As a PS3 owner I didnt get to play the original and due to the senseless nature of the virtual comic being a download I didnt have THAT until my 2nd (current) playthrough.... On first play I admit I was very much playing the game based on how I wanted to deal with individual situations which ended with me having the whole crew trying to pull me into bed but it also left a problem 2nd playthrough as I tried to make decisions based on wanting to keep the same Shep intact (Krystal Shepard if you must know) but I came unstuck by the order that I did the missions second time round and ended up unable to choose to kill Samara as I hadnt done enough missions to have the speech level up..... as I hadnt high enough speech so I agree with you
I did however use the Comic on 2nd playthrough and have chosen to kill Kaiden (found him annoying in the short meeting I had with him) saved the councillors and killed the Rachni Queen so I'm intrigued to see how this develops in the final part
What also killed a lot of enjoyment for mePosted: Jan 12, 2012 12:00AM PST by ThuperThathy
was the lack of RPG elements. It was all so streamlined.
I dunno...Posted: Jan 13, 2012 12:00AM PST by ActivisionStoleMy360
I liked Mass Effect 2, though I feel ME1 was a bit more compelling, the whole paragon/renegade sort of gave you incite into what your language could have been (played through as each). While I dont like the idea of it being restricted, I suppose I understand..
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- Game:
- Mass Effect 3
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- Xbox 360, PS3, PC, Wii U
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- Action
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- Electronic Arts
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- BioWare
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- Rating Pending
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Sergio Gallegos
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Jose Benitez
Tom Piombo
T Spell
Which of the following phrases is from BioShock?
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Created by: Tate P.
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Which of the following phrases is from BioShock?
Created by: Alice Liang
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Created by: Tate P.
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Report: Federal Unemployment Insurance Reduces Hardship for Families and Children
Posted by: Mitchell Hirsch on Nov 19, 2012
The importance of federal unemployment insurance in alleviating serious hardship for workers and their families is highlighted in a new report today from the National Employment Law Project (NELP). The report features the story of Jordan Douglas from Texas, a single mother of a 2-year-old son who is in danger of having her benefits cut off at the end of the year if Congress fails to renew federal unemployment insurance.
Jordan Douglas, 24, of Pampa, Texas, a single mom with a two-year-old son, was laid off in February 2012 from her job of seven years as a licensed vocational nurse. Enrolled in an RN transition program, she looks to graduate as a registered nurse in May 2013.
"But if Congress fails to reauthorize federal unemployment insurance and my benefits are cut off at the end of the year, I'd likely be forced to leave the RN program and lose the bridge to a better-paying job that those benefits provide."
"Unemployment insurance allows me to keep paying our rent, my car payment, and to feed and clothe my son. While I am in school, it allows us to sustain ourselves. Without it, we wouldn't make it to the graduation as an RN in May that I've been working toward."
"I'm working hard to prepare myself for the better health care job I need. So far, unemployment insurance has kept me and my son from serious financial hardship. But, unless Congress renews the federal EUC benefits,
not only will that hardship hit us fast, but if I can't finish my RN program, my prospects for that better job will recede quickly as well."
From the report, part of a series of upcoming issue briefs to support Congressional reauthorization of the federal Emergency Unemployment Compensation (EUC) program:
The Issue
This holiday season, Americans give special thanks for the blessings of food, shelter and community, and we reach out to help our fellow citizens in need. With this same spirit, Congress should immediately address the profound crisis confronting two million unemployed Americans who face an abrupt cut-off from federally funded unemployment insurance at the end of December. Congress must act to renew the Emergency Unemployment Compensation (EUC) program through 2013. The EUC program goes a long way to prevent economic hardship and reduce poverty for millions of U.S. workers and their families.
The Facts
As documented by a recent Congressional Research Service study, unemployment insurance has provided a lifeline for struggling workers to shelter, feed and sustain their families during the worst economic downturn since the Great Depression.
- In 2011 alone, unemployment insurance supported 26 million workers and their families, lifting 2.3 million people out of poverty, including more than 600,000 children.
- Unemployment insurance reduced the poverty rate for families receiving it by 40 percent.
- Were it not for unemployment insurance, the increase in the number of Americans living in poverty would have doubled over the last year. (While the number of people in poverty grew by 2.3 million from 2010 to 2011, unemployment insurance prevented an additional 2.3 million Americans from joining their ranks.)
Renewing the EUC program through 2013 not only extends a critical lifeline that will keep millions of workers out of poverty, but also strengthens the long-term well-being of America's children and families, given the social costs associated with child poverty and severe economic hardship.
On average, U.S. workers collect just $291 a week in EUC benefits. While that covers only 40 percent of the average family's basic expenditures on food, housing and transportation, without this basic measure of economic security, many families would be entirely destitute. By renewing the EUC program through 2013, Congress will offer hope and help restore a sense of economic security to the workers hit hardest by the recession and slow recovery, as they continue their search for new employment.
Congress Must Act
Congress should immediately renew the Emergency Unemployment Compensation program through 2013, and provide additional funding to support model programs that address the employment needs of the long-term unemployed.
Click here to send a message to Congressional leaders: Don't Push Jobless Americans Off the Cliff! Renew Unemployment Insurance for 2013.
Are you facing the Dec. 29 cut off of federal Emergency Unemployment Compensation (EUC) benefits if Congress fails to reauthorize EUC for 2013? Tell us your story.
See all blog entries »


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Use It's Me 247 Mobile Web Banking to manage your accounts while out of town! To access mobile banking, simply log in to online banking from your smartphone and you will be automatically directed to the mobile version.
What's Black and White and "Read" All Over?
Financial statements! So be sure to shred your important documents before you discard them, because raccoons aren't the only ones who sift through trash. Visit cusecure.org to learn more about keeping your money secure.
Don't Give Your Money the Day Off This Labor Day!
Make sure your money continues working for you by earning dividends! View our current certificate and share rates today! To get started, log in and click New Accounts.


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In this video, Robert tells you if you really need to tune your piano if you ever need to move it.
Added Oct 28, 2015
In this video, Robert tells you if you can actually replace one of your piano's strings, in case, accidentally, gets broken.
Added Oct 22, 2014
In this video, Robert tells you what a "prepared piano" is, and what it really means, with a practical demonstration.
Added Oct 8, 2014
In this video, Robert answers a very common question among pianists, and the answer may not be as easy as you'd think.
Added Oct 15, 2014
In this video, Robert gives you some tips to give away a piano that you don't want anymore.
Added Sep 30, 2015
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Now Playing
Want To Make A Creative City? Build Out, Not Up
Urban density spurs innovation. But it turns out that some kinds of density are better than others. Richard Florida, author of The Rise of the Creative Class, Revisited, explains how going vertical can mute creativity, and spreading out can enhance it.


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Wednesday, June 4, 2014
A recent press release from Dorchester District Two invites parents and community members to participate in a six-session parent education series to learn more about world class expectations for learning.
To ensure all students are ready for success after high school, DD2 has adopted learning expectations meant to establish clear, consistent guidelines for what every student should know and be able to do in math and English language arts from kindergarten through 12th grade.
The expectations are a combination of Common Core State Standards and College and Career Readiness Standards and are designed to ensure students are prepared for todays entry-level careers, freshman-level college courses, and workforce training programs.
The learning expectations focus on developing the critical-thinking, problem-solving, and analytical skills students will need to be successful. The new expectations also provide a way for teachers to measure student progress throughout the school year and ensure that students are on the pathway to success in their academic careers.
In working toward this common goal, DD2 and the Greater Summerville/Dorchester County Chamber of Commerce will host a six-session parent education series to review and discuss the components of our world class expectations for learning. Parents, community members and business leaders are invited to learn more about what students are now expected to know and be able to do at every grade level.
The goal of the parent education series is to promote clarity and understanding within the community. All sessions will be held from 6 to 7:30 p.m.
Session dates, locations and topics are as follows:
June 4 - Bethany United Methodist Church: ELA Middle, Creating World Class Learners: Using Text Based Evidence To Answer Document Based Questions.
June 19 - Canaan United Methodist Church: ELA High,
So, Does That Mean Kids Wont Be Reading Any Fiction?
July 15 - Old Fort Baptist Church: Math High, Making Math Relevant, Not One More Thing to Memorize.
July 29 - Miles Road Baptist Church: ELA elementary, Learn to read, read to learn.
Aug. 7 - Summerville Church of Christ: Math elementary, learning blocks of math
Aug. 13 - St. Paul Episcopal Church: Math middle, Why Justify?: The Power of Conversation in Math.
© 2016 The Journal Scene an Evening Post Industries company. All Rights Reserved.
Registration on or use of this site constitutes acceptance of our Terms of Service, Privacy Policy and Parental Consent Form.


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Shaon Stephenson racked up 105 yards and two touchdowns on 15 carries to lead Paterson Kennedy to a 14-6 victory over Ferris on Friday night in Paterson.
Malik McNeil's 35-yard touchdown pass to Jaleel James in the second quarter gave Ferris a 6-0 advantage. Stephenson scored on a 27-yard run in the third quarter and bolted for a 4-yard score in the fourth quarter for Paterson Kennedy.


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Imagine a place where art, science, history, music, theatre, dance, films, camps, classes and professional world-class entertainers all live under one roof! This is Midland Center for the Arts, a beautiful landmark facility where people of all ages are invited to create as well as appreciate and explore these many areas of interest. With two performance venues, two museums, art studios, lecture halls, a historical campus and more, Midland Center for the Arts is unique among arts centers: it encourages participation in as well as appreciation for art, music, science and history.
Located in Midland, Michigan, Midland Center for the Arts is just a 2-hour drive from Detroit, Grand Rapids, and Traverse City, enjoys handy access to US-10 and M-20, and offers convenient amenities to make your visit a pleasure:
- Ample free parking with safe, easy access to the building
- A gift shop where you'll find unique and beautiful items
- Our Saints & Sinners Lounge where you can enjoy a drink, meet friends and relax before and after the show
"Midland Center for the Arts envisions a world where the arts, sciences and humanities are not a frill, but a fuel for innovation, creativity, inspiration and fulfillment. It's a magical place in our community, celebrating who we were, who we are and who we will be. There are so many ways you can help the Center stay vibrant! Volunteer your time, talent and energy; attend a performance or exhibit; purchase a subscription; or make a donation – and invite a friend to do the same! Visit Midland Center for the Arts to find out what it will mean to you!"
~ Terri Trotter, President & CEO
Midland Center for the Arts is composed of six member groups: Alden B. Dow Museum of Science & Art, Center Stage Choirs, Center Stage Theatre, MATRIX:MIDLAND, Midland County Historical Society and Midland Symphony Orchestra.


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Patients living with scleroderma, a chronic autoimmune disorder in which the immune system attacks healthy body tissue, can learn more about their condition, treatment and research at a free seminar Saturday at the Providence Cancer Center Amphitheater, 819 N.E. 47th Ave.
The seminar, which begins at 10 a.m. and will last through mid-afternoon, will feature:
** Dr. Steven S. Overman of The Seattle Arthritis Clinic, co-author of "You Don't LOOK Sick: Living Well with Chronic Invisible Illness."
** Dr. Allison Siebecker, medical director of the Small Intestine Bacterial Overgrowth Center for Digestive Health at the National College of Natural Medicine Clinic in Portland.
** Dr. Jonathan R. Lindner, an Oregon Health & Science University cardiologist.
The event is organized annually by the Oregon chapter of the Scleroderma Foundation, which, among other work offers support groups and other resources for those with the condition.
Walk-in registration is available beginning at 9 a.m. Saturday but the foundation encourages pre-registration. Call Donna Stone at 360-887-2360, or email her: email@example.com.
Scleroderma afflicts about 300,000 Americans and its cause is unknown.
-- Katy Muldoon


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Watch stocks you care about
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It's a 100% FREE Motley Fool service...
Buying and holding companies that are essential to everyday life has helped build plenty of fortunes for those willing to let it work over the long term. And if you look to the tech space, it's fair to say that search giant Google (NASDAQ: GOOGL ) is one of the most essential tools available today. Millions of people use the company's popular search service daily almost out of habit. And while investors and consumers rarely consider just how much they rely on Big G, we recently saw how impactful even a tiny hiccup from the web giant's services can be to the entire Internet.
In this video, tech and telecom analyst Andrew Tonner discusses Google's recent outage and why even after the company's impressive run so far this year, it's still a company worth owning.
The future of the trillion-dollar revolution in mobile has change the game for many of tech's biggest names, and Google is no exception. To find out if Google is set to dominate the next decade, we've created a free report called "Who Will Win the War Between the 5 Biggest Tech Stocks?" Inside, you'll find out which companies are set to dominate and give in-the-know investors an edge. To grab a copy of this report, simply click here -- it's free!


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It's appropriate that we deal with political leftovers on a Saturday where people are still shopping, traveling and generally more interested in football than whether the Obamacare website will function properly tomorrow.
Let's pontificate about the state's favorite subject of late: Jersey City Mayor Steve Fulop. Fulop is in that phase were pundits and observers are trying to determine his place in the state's political firmament. Celebrity pol Cory Booker has gone to the U.S. senate and Steve is the shiny new toy. From Day One, Fulop has had the office of governor on his mind. He dare not utter the words – "That's for you to say," he would respond when asked. He could kill speculation, but prefers coyness. Fulop has several years to raise campaign money and tell everyone who he is. His inner circle knows it means nothing if the mayor cannot make meaningful changes for the better.
Previous administrations believed in the Walter Mitty "pocketta, pocketta" method of governing. When Fulop's administration took office, it hit the ground running, and this new bunch believes the best way to make changes is having nearly full control of res publica. Well, the administration of former Mayor Jerramiah Heally wanted the same thing, but more for political reasons rather than decent urban planning.
This new administration's autocracy has been boosted by having majority control of the City Council. A key move was transforming the Mayor's Action Bureau into the Resident (or People's) Response Center, centralizing machinery that has devoured the cultural, seniors, veterans, and immigration offices and now has jurisdiction over real estate development.
There are several ways to look at this consolidation. One is that it is a good thing. You are streamlining government by eliminating competing interests and reducing bureaucratic bloat. By doing so, you're declaring yourself a realist who is willing to make practical decisions that moves the city forward rather than an idealist who freezes the governmental process in a bid to become all inclusive. It sounds like I'm promoting a dictator but those City Council critics and neighborhood associations will keep officials on their toes.
Where this city and the mayor is headed may become a bit clearer once Fulop gives his first State of the City speech about a month into the new year.
-- Yesterday, the West New York school board scheduled a special election for two school trustees to one-year terms on Jan. 28. This will expand the number of school board members to nine. The town will select three members of the panel in April to three-year terms. There will be three seats up for grabs every year, thanks to the approval earlier this month of a referendum calling for school elections, rather than appointing them. Usually, this is the first step in trying to take Town Hall. Ultimately, we'll have to ask the question, other than Freeholder Jose Munoz, who wants to control local government?
-- I would be remiss by not mentioning that town Commissioner and mayoral hopeful Count Wiley handed out 500 turkeys, mostly to senior citizens. One local political wag said it was not certain whether some of the seniors knew Wiley and that one of the elderly told the commissioner to thank Union City Mayor and Sen. Brian Stack for the bird.
Hey, handing out these frozen dinners is how you get people to pick you out o fthe flock.
-- Bayonne Police Capt and mayoral hopeful James Davis held a meet and greet yesterday evening at the Victoria Tavern. So how did it go? I hear there's also a fund-raiser planned for next week at the Villa Maria. Tell me if the Victoria Tavern gets cited for anything.We are in Hudson County, right.
-- Happy leftovers. See you at the Pearl Harbor anniversary.


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High Dose Chemotherapy and Autologous Transplant for Neuroblastoma
This study is currently recruiting participants. (see Contacts and Locations)
Verified August 2016 by Masonic Cancer Center, University of Minnesota
Masonic Cancer Center, University of Minnesota
Information provided by (Responsible Party):
Masonic Cancer Center, University of Minnesota
ClinicalTrials.gov Identifier:
First received: January 31, 2012
Last updated: August 15, 2016
Last verified: August 2016
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Detailed Description:
This is a standard of care document, outlining the therapy for children with high risk neuroblastoma who are not eligible for Children's Oncology Group (COG) studies.
Drug: Carboplatin
Biological: Autologous stem cell infusion
Biological: Granulocyte colony stimulating factor
Radiation: Radiation therapy
Drug: Isotretinoin (13-cis-retinoic acid)
Drug: Melphalan
Drug: Etoposide
|Study Type:
|Study Design:
|Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|High Dose Chemotherapy and Autologous Peripheral Blood Stem Cell (PBSC) Rescue for Neuroblastoma: Standard of Care Considerations
Resource links provided by NLM:
Genetics Home Reference related topics: neuroblastoma
MedlinePlus related topics: Neuroblastoma
Drug Information available for: Melphalan Melphalan hydrochloride Isotretinoin Etoposide Carboplatin Etoposide phosphate Lenograstim Granulocyte colony-stimulating factorU.S. FDA Resources
Further study details as provided by Masonic Cancer Center, University of Minnesota:
Primary Outcome Measures:
- Number of Patients with Successful Engraftment [ Time Frame: Day 42 ] [ Designated as safety issue: No ]The time to neutrophil engraftment will be assessed by standard statistical approaches.
Secondary Outcome Measures:
- Number of Patients with Disease Free Survival [ Time Frame: 2 Years ] [ Designated as safety issue: No ]The number of patients alive and disease free will be assessed using standard statistical approaches.
- Overall Survival [ Time Frame: 2 Years ] [ Designated as safety issue: No ]The number of patients alive will be assessed by standard statistical approaches.
- Number of Patients with Treatment Related Death [ Time Frame: 1 Year ] [ Designated as safety issue: Yes ]The rate of treatment related mortality will be assessed by cumulative incidence approach.
- Number of Patients with Disease Free Survival [ Time Frame: 5 Years ] [ Designated as safety issue: No ]The number of patients alive and disease free will be assessed using standard statistical approaches.
- Overall Survival [ Time Frame: 5 Years ] [ Designated as safety issue: No ]The number of patients alive will be assessed by standard statistical approaches.
|Estimated Enrollment:
|Study Start Date:
|March 2012
|Estimated Study Completion Date:
|February 2018
|Estimated Primary Completion Date:
|February 2017 (Final data collection date for primary outcome measure)
|Assigned Interventions
Patients Treated for Neuroblastoma
According to patient weight and renal function, consolidation chemotherapy using various doses of Melphalan, Etoposide, and Carboplatin followed by autologous stem cell infusion and serial post-transplant Granulocyte Colony Stimulating Factor, radiation therapy and Isotretinoin maintenance therapy.
Drug: Carboplatin
Carboplatin intravenously (IV), 425 mg/m2/dose (or if ≤ 12kg, 14.2 mg/kg/dose) once daily x 4 doses on days 7 through 4 pretransplant.
Other Name: ParaplatinBiological: Autologous stem cell infusion
On day 0 the stem cells will be infused immediately after thawing over 15-60 minutes per institutional guidelines.Biological: Granulocyte colony stimulating factor
Beginning on day 0 after infusion of the PBSC, patients will receive G-CSF subcutaneously (SQ) or IV (SQ preferred) 5 micrograms/kg once daily and continuing once daily until post-nadir absolute neutrophil count (ANC) > 2000/μL for 3 consecutive days.
Other Name: G-CSFRadiation: Radiation therapy
It is suggested that patients who have a complete surgical resection of the primary tumor receive 21.6 Gy external beam radiation therapy (EBRT) to the post-induction chemotherapy, pre-operative primary tumor volume. It is suggested that patients who have an incomplete surgical resection of the primary tumor (residual soft tissue mass measuring >1 cm3) will receive 21.6 Gy EBRT to the postinduction chemotherapy, pre-operative primary tumor volume and an additional boost of 14.4 Gy EBRT to the gross residual tumor (total dose 36 Gy to gross residual tumor volume). Radiation should be given after stem cell transplantation and should start no sooner than 28 days post transplant.Drug: Isotretinoin (13-cis-retinoic acid)
Post-transplant maintenance therapy with cis-RA daily for 14 days every 28 days repeated for 6 months. This phase of the therapy can be initiated by the BMT team and continued by the referring physician. It is recommended to begin Isotretinoin at day 66 post-transplant and no later than day 100. For patients ≤12 kg, isotretinoin (accutane) should be administered at 5.33 mg/kg/dose divided twice daily. For patients >12 kg isotretinoin (accutane) should be administered at 160 mg/m^2/day divided twice a day. Patients should be considered for monoclonal antibody therapy against GD2, such as ch14.18 if such trials are available.
Other Name: AccutaneDrug: Melphalan
Melphalan Intravenously (IV), 70 mg/m2/dose (or if ≤ 12 kg, 2.3 mg/kg/dose) once daily x 3 doses on days 7 through 5 pretransplant
Other Name: AlkeranDrug: Etoposide
Etoposide intravenously (IV), 338 mg/m2/dose (or if ≤ 12kg, 11.3 mg/kg/dose) once daily x 4 doses on days 7 through 4 pretransplant
Other Names:
Detailed Description:
This therapy involves the use of melphalan, etoposide, and carboplatin (consolidation chemotherapy); autologous stem cell rescue, post-transplant radiation therapy and a maintenance phase with Isotretinoin (Accutane, 13-cis-retinoic acid) therapy. If available, patients should also consider post-transplant therapy with cytokines and monoclonal antibody (ch14.18) on a COG or New Approaches to Neuroblastoma Therapy (NANT) trial.
|Ages Eligible for Study:
|up to 30 Years (Child, Adult)
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Less than 30 years of age at diagnosis of neuroblastoma
- No evidence of disease progression: defined as increase in tumor size of >25% or new lesions
- Recovery from last induction course of chemotherapy (absolute neutrophil count > 500 and platelet > 20,000)
- No uncontrolled infection
- Minimum frozen peripheral blood stem cells (PBSCs) of 2 x 10^6 CD34 cells/kg for transplant are mandatory and 2 x 10^6 CD34 cells/kg for back-up are strongly recommended (thus, PBSC of 4 x 106 CD34 cells/kg is encouraged)
Adequate organ function defined as:
- Hepatic: aspartate aminotransferase (AST) < 3 x upper limit of institutional normal 8 Cardiac: shortening fraction ≥ 27% or ejection fraction ≥ 50%, no clinical congestive heart failure 8 Renal: Creatinine clearance or glomerular filtration rate (GFR) > 60 mL/min/1.73m^2 If a creatinine clearance is performed at end induction and the result is < 100 ml/min/1.73m^2, a GFR must then be performed using a nuclear blood sampling method or iothalamate clearance method. Camera method is NOT allowed as measure of GFR prior to or during Consolidation therapy for patients with GFR or creatinine clearance of < 100 ml/min/1.73m^2
Exclusion Criteria
- Patients with progressive disease should consider participating in phase I studies since consolidation therapy using the regimen outlined in this document have not been determined to be useful.
- Patients who are delayed in consolidation chemotherapy beyond 8 weeks, and don't meet organ function criteria.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01526603
Please refer to this study by its ClinicalTrials.gov identifier: NCT01526603
|Contact: Patricia Kleinke
|United States, Minnesota
|Masonic Cancer Center, University of Minnesota
|Minneapolis, Minnesota, United States, 55455
|Contact: Michael R. Verneris, M.D. 612-626-2961 email@example.com
|Principal Investigator: Michael R. Verneris, M.D.
Sponsors and Collaborators
Masonic Cancer Center, University of Minnesota
|Principal Investigator:
|Michael R. Verneris, M.D.
|Masonic Cancer Center, University of Minnesota
More Information
Keywords provided by Masonic Cancer Center, University of Minnesota:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 29, 2016
|Responsible Party:
|Masonic Cancer Center, University of Minnesota
|ClinicalTrials.gov Identifier:
|NCT01526603 History of Changes
|Other Study ID Numbers:
|Study First Received:
|January 31, 2012
|Last Updated:
|August 15, 2016
|Health Authority:
|United States: Institutional Review Board
Keywords provided by Masonic Cancer Center, University of Minnesota:
peripheral blood stem cell transplantation
autologous stem cell transplant
Additional relevant MeSH terms:
Neuroectodermal Tumors, Primitive, Peripheral
Neuroectodermal Tumors, Primitive
Neoplasms, Neuroepithelial
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms, Glandular and Epithelial
Neoplasms, Nerve Tissue
Etoposide phosphate
Antineoplastic Agents
Antineoplastic Agents, Phytogenic
Topoisomerase II Inhibitors
Topoisomerase Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Antineoplastic Agents, Alkylating
Alkylating Agents
Myeloablative Agonists
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs
Keratolytic Agents
ClinicalTrials.gov processed this record on September 29, 2016


text:
Other projects made by sewbug57:
Offer some kudos...
Join the conversation...
Ask a question...
Add your comment...
|Here are some details about my project:
|Casual, Funky, Whimsical
What was your source for this quilting project?
Online Photo or Website
Name of website or photo Rhymes With Baby from BH&G Sew Scrappy Magazine Vol.2 Oct.. 2011
What are you most proud of? That I FINALLY got up the nerve to do the cross-hatch method for quilting this. I think it worked well for this quilt and I'm very happy with the results.
wow. The quilt is beautiful, for any age. thank you for sharing


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Jenna Fischer Had a Mini Office Reunion on Instagram
Pam caught up with her Office buddies.By Madeline Raynor
Pam caught up with her Office buddies.By Madeline Raynor
She might co-star in it.By Sean Fitz-Gerald
They'll appear in an early season three episode.By Zach Dionne
Actress Angela Kinsey hosts them at her house (complete with Yankee Swap). And she isn't scared of alcohol.By Denise Martin
On Fox, where her former co-star Mindy Kaling hangs out.By Zach Dionne
Alongside Rachael Harris.By Margaret Lyons
From the cast of Moneyball to Glee, check out last night's Red Carpet at the SAG Awards.By Eric Sundermann
Plus: Jimmy Kimmel couldn't give Shaq a piggyback ride the way his tiny girlfriend could, and more, on our daily late-night roundup.
"I've made an enormous mistake."By Kyle Buchanan
Everyone who's anyone, and anyone who's dressed.By Alex Rees
Plus: Whitney Houston's crappy singing is all her friend's fault.