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Behind a 55-point second half, the Hokies came back from an 11-point deficit to pick up their biggest win of the season over the 23rd ranked wake forest demon deacons, 87-83. With the win, the Hokies move into sole possession of second place in the ACC as they now prepare for first place duke on ACC Sunday Night Hoops.
Malcolm Delaney led the way tonight with 31 points and 9 rebounds. The 31 was one off his season-high of 32 against temple. For those of you Hokies who use Twitter, you probably follow @foe23 (that is Malcolm's username) and might have noticed the tweet below from earlier in the day:
Delaney rarely tweets about games, so his prediction caught my attention and he certainly delivered. He kept the Hokies within single digits at halftime by scoring almost half of the Hokies first-half points (15 of 32). His three-pointer (although his toe was on the line) at the 6:30 mark in the second half completed the Hokies second-half comeback by giving Tech its first lead, 70-69, since the first half when they led briefly, 12-11. But Delaney's biggest play of the game might have occurred a couple minutes earlier.
With the Hokies down by four with nine minutes to play, C.J. Harris stripped Terrell Bell in the backcourt. Harris was on the verge of converting the steal into a layup when Terrell made up for his mistake by swatting Harris' shot into the hands of Delaney. Delaney raced down the length of the court, drove down the lane and made an acrobatic layup as he was fouled by Chas McFarland. It was McFarland's 5th foul, and after Delaney made the free throw, the Hokies had cut the lead to one. It was a five-point turnaround, which also resulted in one of the deacs' big men fouling out.
Helping Delaney on the offensive end tonight were the usual suspects, Dorenzo Hudson with 21 and JT Thompson with 16. Hudson continues to shine as our second best offensive weapon averaging 18 points per game since January 1. Jeff Allen was somewhat of a non-factor tonight, picking up four fouls with 16 minutes to go in the game.
If it were not for some poor free throw shooting by the Hokies in the final 90 seconds and the performance of Ish Smith, the Hokies might have won by double digits. Smith played a stellar game for the deacs as an assist maker in the first half and the only scorer in the final minutes of the second half.
During the first 30 minutes of the game, I was really impressed with the deacs balanced attack. They clearly are the best team that the Hokies have played all season. wake's super sophomore Al-Farouq Aminu scored 21 points in the first 20 minutes, which is 5 shy of his career high. But the Hokies didn't let Aminu reach a new career mark as he only pitched in four points in the entire second half. L.D. Williams picked up the slack for Aminu in the second half though and had a career shooting night. He finished with 19 points on 9 of 11 shooting, which is 11 points above his average. Bottom line, the 83 points given up by the Hokies were 22 points above their season average. It could have been much worse as wake reached the 61 point mark with 12 minutes to go in the game.
This should keep Virginia Tech off the bubble radar of bracketologists for awhile although I think it was total BS to call this a "must-win" game. There are plenty of games left to win. It definitely was our best opportunity for a high quality win, and we capitalized on it. That's what this team has been about all season. Tech is winning the games that they should win and has lost when they were clear underdogs (except for the miami loss). If you've followed the Seth Greenberg era at Tech, this is not a characteristic of his teams. Past Greenberg teams have often tripped up against inferior competition and shocked the likes of #1 unc and wake forest or produced magical wins at duke and carolina. Let's hope some of that past magic comes alive again this Sunday night in cameron indoor.
Cope-acabana's Notes:
- The 55 second-half points by the Hokies are the most in a half by the Hokies since they scored 54 against Morgan State on March 19, 2008, in a 94-62 Virginia Tech win. I went back four seasons and that's the closest the Hokies have come to 55 points in a half. Beyond that, the stats aren't readily available on HokieSports.com. The record for second-half points for Tech is 73 vs. Florida State on Nov. 30, 1981.
- With the win, the Hokies even the all-time series between the two schools at 26.
- Tech improves to 6-2 in ACC play against the deacons, including an ACC tournament win in 2007.
- The Hokies have now won five straight ACC games, a new record for Tech since joining the conference in 2004.
- Tech is now 14-0 at the Cassell this season.
- Delaney is the ACC's leading score in ACC-only play with 22 points a game. Dorenzo Hudson is the conference's 7th leading scorer (after tonight) with 16.6 per game.
- Two stat categories that blew my mind when I saw the final box score were blocks and rebounds. Somehow, the Hokies out-rebounded the much bigger deacons 47-38 and blocked more shots (7) than wake (5). Considering just how much bigger inside wake is than Tech, I'd say that's a major point of congratulations.
- Terrell Bell was a big reason for the Hokies' rebounding edge by pulling down a career-high 14 boards. It was also the most rebounds by a Hokie this season. Allen had 13 against vmi and seton hall.


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on December 28, 2013 - 12:01 AM
The latest Dietary Guidelines for Americans recommend increasing "the amount and variety of seafood consumed by choosing seafood in place of some meat and poultry." But, why?
The main reason is that fish and other seafood contain two omega-3 fats associated with a reduced risk for heart problems: docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA).
Science suggests that eating about 8 ounces of a variety of seafood each week – which provides a daily average of about 250 mg of DHA/EPA – may convey these heart-healthy benefits. Problem is, most of us aren't getting the recommended amounts.
Try the following ideas to help you get more:
1. Go for omega-3-rich fish: While all seafood contains some omega-3 fats, fatty cold-water fish have higher concentrations. Popular omega-3-rich picks include salmon and sardines (both provide more than 1,000 mg per 4-ounce serving) and tuna (about 250 mg per 4 ounces of light tuna).
2. Try some seaweed: Need a reason to eat sushi? Seaweed (nori) and kelp (wakame, kombu or dulse) are both algae, which provide some DHA/EPA.
3. Consider fortified foods: More and more food products fortified with DHA/EPA are finding their way to supermarket shelves. The following are foods that you might find fortified with DHA/EPA:
• Eggs: Eggs are fortified by adding flaxseed and/or algae supplements to hens' feed. One large egg may contain up to 500 mg omega-3s (some of which is DHA/EPA).
• Milk: Some brands of milk add fish oil or algal oil to give a DHA/EPA boost (don't worry, you can't taste it!). One cup of this fortified milk delivers up to 50 mg of DHA/EPA.
• Peanut butter: As with milk, some brands are adding fish oil. A 2-tablespoon serving provides about 30 mg DHA/EPA.
4. Talk with your doctor about supplements: If you don't eat a lot of fish, taking an omega-3 supplement might be a smart choice. Talk with your doctor about whether supplementation might be right for you and, if so, what to look for on labels.


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Currency, Equity, India, Market News
Surprise! India's Equities Hit New Record High
On March 10, 2014, the S&P BSE SENSEX Index hit a record high—21,934.1 Many U.S. investors might be surprised by this fact, in that the experience of a typical investor accessing India's equities has not been indicative of a market strong enough to surpass its own January 20082 and November 20103 highs.
U.S. Record Highs vs. India's Record Highs
U.S. equity markets, such as the S&P 500 Index, are performing well and continuing to trend toward periodic record highs. This is what investors expect when the term "record high" is used—a strongly positive performance. With India, the single word that comes to mind to characterize the current experience is volatility. This equity market, at least from our perspective in the U.S., has been driven less by the fundamentals of the underlying stocks and more by macroeconomic sentiment regarding either India itself or broader emerging markets.
Currency Can Cut Deeply
The critical link that we've thus far left out is India's currency, the rupee. A U.S. investor typically accesses India's equity market with valuation or other fundamentally related factors in mind. However, as with any other foreign equity investment, the country's currency becomes a second position for the investor. Recall that whenever the purchase of foreign equities is involved, an investor has to sell U.S. dollars and buy a foreign currency—in this case Indian rupees—to buy the foreign stocks. The rupee has been particularly volatile and has behaved as somewhat of an economic barometer, reflecting changes in investor sentiment.
How Influential Has the Rupee's Performance Been?
Looking back to August of 2013, as the S&P BSE SENSEX Index was trending upward toward a record high, the rupee was actually diving to a record low—an exchange rate of nearly 70 per U.S. dollar4. At this point in time, investors were very concerned with India's current account deficit, and there was also deteriorating confidence in India's fiscal and monetary policies. Since then, the rupee has strengthened back to a level closer to 60 per U.S. dollar, which is still approximately 50% weaker than the levels seen as recently as the end of July 2011.5
Illustrating the Issue for U.S. Investors
We've set up a veritable tug-of-war between India's equities and its currency, and the currency has been dragging down market performance for U.S. investors.
Looking at Profitable Firms in India
WisdomTree created an Index of India's equities to measure the performance of the country's profitable companies. Its inception date was in December 3, 2007. What has the performance experience been over this period?
India's Currency Has Been a Major Headwind for Equity Returns
• Volatility Clearly Evident – Whether looking at the WisdomTree India Earnings Index measured in U.S. dollars or in Indian rupees, it's pretty clear that the market has been very volatile. Generally speaking, India is a higher beta emerging market country, and the WisdomTree India Earnings Index is broadly inclusive of profitable companies, including even small-cap firms as constituents.
• Large Currency Impact – Given our inception date, the chart makes it clear that currency has been the primary factor leading to negative returns—as the equities in local currency terms are in net positive territory and close to all-time highs. Cumulatively, the rupee has depreciated nearly 36% against the U.S. dollar over this period. Measuring the performance of the WisdomTree India Earnings Index in rupees shows a cumulative return of over 7.5%, a positive figure. But accounting for the exchange rate depreciation brings this cumulative return down to a negative 31%.
Evaluating India as an Opportunity Today
Given this illustration, we believe it is impossible to evaluate the case for India's equities without also considering factors that could potentially influence the performance of its currency in a positive way. Even with the S&P BSE SENSEX Index hitting record highs, it's just as important to think about the things that can keep the currency from sliding back in the future.
Over the last seven months, several developments have enhanced the resiliency of the Rupee and create a stronger backdrop for US investors to allocate to Rupee denominated assets.
• Renewed Central Bank Credibility – The new central bank governor, Raghuram Rajan has helped restore market confidence in the inflation fighting credentials of the Reserve Bank of India, by pro-actively hiking rates to stem inflationary pressures. Additionally, the RBI has re-built FX reserves and re-anchored FX expectations, reducing volatility.
• Reduced external vulnerabilities – The current account deficit has improved dramatically. At close 2% of GDP, it is less than of last year's 4.7% deficit. Solid export growth amid a curb in gold imports and a fall in non-oil imports triggered the improvement.
• Less Heat from Inflation – The pace of headline inflation has turned significantly dropping from double-digits to 8% for consumer price inflation (CPI). Core CPI, however, remains sticky at 8%. Inflation expectations remain elevated, providing some underpinning to the RBI's more hawkish stance.
• Greater Fiscal Restraint – The government has slowly worked to tighten the government's belt in the last year. The recently proposed fiscal deficit of 4.6% of GDP exceeded expectations of 4.8%.
• Building consensus for pro-business candidate – Though elections do not start until April, a consensus in the polls is forming behind Narandra Modi and his opposition Bharatiya Janata Party (BJP). A growing number of strategists and business leaders feel that the prospects for change under the BJP could inject an immediate boost to investor confidence. The confidence is likely to be extremely supportive of the Rupee and Rupee-denominated assets.
These developments have fostered investor sentiment that India is pro-actively addressing its vulnerabilities and unlocking the growth potential that has stagnated in recent years.
Conclusion: Should We Have Been Hedging the Rupee?
As we consider all these factors, we hope that the divergence between the concept of record highs and the experience of U.S. investors has become clearer. The astute reader might question one thing, however: Given WisdomTree's success with currency-hedged equity strategies, an obvious answer could have been to simply hedge the rupee. In a future blog post, we will address why this may not be the best approach to solving the disconnect between India's equity and currency performances.
1Source: Bloomberg.
2January 8, 2008: SENSEX level at 20,873.
3November 5, 2010: SENSEX level at 21,004.
4Source: Bloomberg; refers to 8/28/2013, when it took 68.83 rupees to purchase 1 U.S. dollar.
5July 28, 2011: rupee vs. U.S. dollar exchange rate was 44.07.
Important Risks Related to this Article
Foreign investing involves special risks, such as risk of loss from currency fluctuation or political or economic uncertainty. Investments in currency involve additional special risks, such as credit risk and interest rate fluctuations. Investments in emerging, offshore or frontier markets are generally less liquid and less efficient than investments in developed markets and are subject to additional risks, such as risks of adverse governmental regulation and intervention or political developments. Investments focused in India are increasing the impact of events and developments associated with the region, which can adversely affect performance.


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- Keep wonder of the season going and take advantage of our extended holiday hours.
The holiday season may be nearing its end but that doesnt mean the wonder has to stop!
In fact, at Discovery Place, weve extended our hours so you and your family or friends have more time to enjoy all of the extraordinary experiences our Museum offers.
Today through December 28, we are open 9:00 a.m. 5:00 p.m., giving you an extra hour to learn and explore.
We also will be open New Years Eve and New Years Day.
So what are you waiting for? Get out of the cold and step into a world where science is brought to life!
Filed Under: Inside Discovery


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CALCUTTA - Two recent incidents during heavy snowfall prompted local fire officials to issue a warning to residents to keep their driveways clear.
Calcutta Fire Department's assistant Chief Dave McCoy said Wednesday that emergency personnel have responded to two incidents involving residents having health issues that were aggravated by snow-filled driveways.
On Wednesday, the department responded to a call of a man having heart attack-like symptoms, and McCoy said, "With all the snow, there was no way the ambulance (or fire department vehicles) could get up the driveway."
Article Photos
Firefighters from Calcutta, Glenmoor and Liverpool Township responded Wednesday morning to a report of a structure fire at Sheetz in Calcutta, where employees reported smelling an odor of something burning. Nothing was found by firefighters who searched the interior. (Photo by Jo Ann Bobby-Gilbert)
McCoy and Captain Marty Pike used their own four-wheel-drive pickup trucks to transport paramedics up the driveway to reach the victim, who was then transported back to a waiting ambulance in McCoy's truck.
"We had the same thing last week," McCoy said.
Not only medical issues but fire calls could be hampered by such driveways, McCoy emphasized, pointing out, "By the time we could pull hoses by hand down a driveway, the house could burn down."
He issued the reminder, "If you can't get in or out, neither can fire trucks, fire responders or emergency vehicles. Invest in a tractor or plowing or gravel. We would hate to see someone die because we can't get to them."
Also on Wednesday, firefighters from Calcutta, Glenmoor and Liverpool Township responded to the Sheetz gas station at the corner of St. Clair Avenue and state Route 170 in Calcutta for what was initially reported as a structure fire.
Police at the scene said employees had smelled a burning odor and thought they saw a slight "sheen" in the air.
McCoy said nothing was found inside the store but that employees were being cautious due to a fire that caused damage to the business in the past.
Also responding were several ambulances and St. Clair Township police officers.


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>Sunday, Sept. 27 FOREVER LOVE CBS (9 p.m. ET) Whoa, things have changed. Reba McEntire awakens from a 20-year coma in this TV movie.
Monday, Sept. 28 THE KING OF QUEENS CBS (8:30 p.m. ET) Doug (Kevin James) fears there's fat in his wife's future as this new sitcom enters Week 2.
Tuesday, Sept. 29 BUFFY THE VAMPIRE SLAYER The WB (8 p.m. ET) The season opens with the high school heroine dueling demons in a new city.
Wednesday, Sept. 30 THE SECRET LIVES OF MEN ABC (9:30 p.m. ET) Splitsville's the scene of this sitcom premiere about three guys in different stages of divorce.
Thursday, Oct. 1 FUTURESPORT ABC (9 p.m. ET) Wesley Snipes and Dean Cain play a deadly game in this futuristic (hence the title, folks) TV movie.
Friday, Oct. 2 MILLENNIUM FOX (9 p.m. ET) Frank (Lance Henriksen) gets a new partner (Klea Scott) as the strange series starts its third season.
Saturday, Oct. 3 MARTIAL LAW CBS (9 p.m. ET) Action star Sammo Hung chops into the second week of this cop show.
Picks and Pans Review: Week at a Glance
updated 09/28/1998 AT 01:00 AM EDT
•originally published 09/28/1998 AT 01:00 AM EDT


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<-- Previous Next -- > TOPIC: Query: Twos complement representation
Questions posted: 2 Comments Posted: 1
Actually two's complement is used to represnt negative nos:,, but.....
Pls if anyone of you who reads knows abt it pls reply..
Thanking you in advance
Comments Posted:4
assume 8-bit representation of number.
Two's complement of positive numbers starts with '0'(MSB)
Two's complement of negative numbers starts with '1' (MSB)
+8/ 0000 1000
-8/ 1111 1000
So in 2's comp, when ever it starts with MSB=1, it represents a negative number.
Hope it will help you.
Comments Posted:7 Questions Posted:1
To find twos complement there are two ways
1.Find 1s complement and add 1.
2.as khushin has described above.
Comments Posted:1 Questions Posted:2
MY question is how to find twos complement of +8 and -8? IS there any difference??
Anyway thanks for ur reply
Comments Posted:7 Questions Posted:1
Two's complement representation of numbers is different from normal representation ie using four bits one can represent from 0 to 15 in normal binary,but in two's complement it can represent
only from -7 to +7(three bits) and +8(four bits) {16 numbers in total}.It is similar to sign extended representation of numbers.with 0 in the MSB representing positive numbers and
1 for negative numbers.So +8 and -8 differs only in
MSB.Please correct me incase i am wrong
Comments Posted:8 Questions Posted:6
Consider the 2s complement representation: 11100
We start copying from right to left, and the first digit we copy is a 1 so this gives us:
We complement the remaining digits, which gives us:
We then convert this from binary to decimal, giving us the result of 4
Our original bit pattern in step 1 started with a sign bit of 1, so that means that our original bit pattern represents a negative value in 2's complement, so our final result is: -4.
suppose u want do perform 0-7=-7
using 2's complement
first 0111 now take 2's com.. 1001
so now u convert it to decimal it is not 9 but -7 i think this will help u
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STATE COLLEGE - As long as he remains at Penn State, it's almost certain that Bill O'Brien's name will pop up occasionally for NFL jobs.
His name surfaced Sunday when cbssports.com reporter Jason La Canfora cited sources saying he wouldn't be surprised if the Jacksonville Jaguars and other NFL teams showed interest in O'Brien after this season.
O'Brien wanted nothing to do with the NFL topic Tuesday and said he hasn't given any thought to how he might handle being wooed after the season.
"No, I'm focused on Indiana," he said. "We are at 6-4, trying to get to a seventh win and just really want to do a great job coaching this team, this week, for the Indiana game."
Whether O'Brien eventually decides to leave for the NFL at some point remains to be seen, but one thing should be clear: If he leaves after this season, it could be devastating to the Nittany Lion football program.
The NCAA sanctions allow Penn State players to transfer and be eligible to play immediately at another school all the way up until August. There's already been speculation that a few players might transfer after the season, but if O'Brien were to leave in, say, January, the uncertainty surrounding the program could lead to a mass exodus of players.
Many of O'Brien's assistants also likely would depart, and it would be a tough sell to hire another quality head coach and staff given that there are still three years of bowl ineligibility and five years of severe scholarship limitations remaining.
The players on this team already have endured a difficult year because of the Jerry Sandusky scandal and NCAA sanctions, and if O'Brien were to leave, many of them could decide to go elsewhere rather than deal with another major coaching overhaul.
If more than 15 scholarship players were to depart, and given that PSU can only offer 15 scholarships for the next four years, that would leave the Lions with fewer than 60 scholarship players next year. The recruiting implications also could be significant since O'Brien and his staff have been able to maintain good relationships with several top recruits for next year.
O'Brien can prevent all that major turmoil simply by staying one more year, through the August transfer deadline. But his decision could depend on which NFL teams come after him, how much money he's offered and what's important to his family.
His original five-year contract was extended to nine years because of the NCAA sanctions, and he make $2.3 million per year, plus annual raises. If he resigns at some point, he would have to buy out the remaining years on the initial five-year contract (meaning if he leaves after this year, he'd have to buy out four years, or $9.2 million).
O'Brien was asked if he needs to make a definitive statement about his future given that the season is winding down and there are recruiting implications.
"We're 6-4, I'm flattered that you would ask me that question," he said. "I'm worried about Indiana and our Tuesday practice and looking forward to doing the best we can for this team as a coaching staff for this Indiana game."
Some of the Lions' best young players, such as the so-called "Supa Six," already have indicated repeatedly that they will be staying at Penn State. But that's under the impression that O'Brien would be there also, and their plans could change if he were to leave.
The coach said he doesn't worry about things such as players transferring.
"Do you know what I worry about?" he said. "I worry about my son, I worry about my kids, I worry about my family. Those are things to worry about. I don't worry about things that are out of our control."
His potential NFL future doesn't fall into that category since, ultimately, it would be his decision when or if to leave Penn State.
Carter finished
Redshirt freshman tight end Kyle Carter is done for the season, O'Brien confirmed, after suffering a hand injury at Nebraska. The coach did not give any specifics about the injury.
"I'm not going to get into the details of that yet, out of respect for him and his mom, so I don't want to get into that," O'Brien said. "He had an excellent season for us."
Carter did do that, catching 36 passes, which is just five shy of the school's season record of 41 set by Andrew Quarless in 2009. He's second on the team in catches and receiving yards (453) and grabbed two touchdowns.
"Here is a guy, a young player, that came in here trying to learn a position that is a very difficult position to learn," O'Brien said. "This is, offensively, it's the second hardest position to learn behind quarterback. You're involved in the running game, in protections, you're involved in route running, you have to recognize coverage.
"There are so many different things that you have to know, and I thought as a young player he came in here and did a really nice job. He's got excellent hands, he's a tough kid, he's a great kid, just a really good guy to have on the team."
Willis day-to-day
Safety Malcolm Willis is day-to-day, the coach said, after suffering a knee injury Saturday. He will be evaluated throughout the week to determine his status against Indiana.


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Last year, Facebook (NASDAQ: FB ) raised eyebrows when it agreed to acquire Instagram for a hefty $1 billion, even though the final purchase price ended up a bit lower. The social network recorded $435 million in goodwill on its balance sheet related to the deal, which represents potential risk should Instagram not live up to its lofty expectations.
Inevitably, Facebook would need to monetize the popular photo-sharing service, and that's exactly what's about to happen. Instagram is preparing to launch its ad platform next year, which could potentially be a major opportunity considering its large user base. Facebook has learned a lot building its own mobile ad business, and the company could redeploy those lessons within its Instagram subsidiary.
In the following video, Chris Hill discusses the prospects of Instagram ads with Evan Niu, CFA, and Jamal Carnette.
The tech world has been thrown into chaos as the biggest titans invade one another's turf. At stake is the future of a trillion-dollar revolution: mobile. To find out which of these giants is set to dominate the next decade, we've created a free report called "Who Will Win the War Between the 5 Biggest Tech Stocks?" Inside, you'll find out which companies are set to dominate, and we'll give in-the-know investors an edge. To grab a copy of this report, simply click here -- it's free!


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Your Hollywood party guests will love this keepsake tin as a memento from your event!
Our Hollywood Hills Personalized Mini Cookie Tin may be filled with your own special recipe treats such as candy or cookies. Surprise your party guests with a keepsake tin designed by you, that may be used to store special mementos later. Well print your design on the lid of the cookie tin. Choose from hundreds of design options to create your truly unique design. Each of the 1 3/4 inch high x 6 inch diameter cookie tins allow you to add your own special message.
Cookies not included.
Hollywood image TM & Design © 2010 Hollywood Chamber of Commerce. The Hollywood Sign and Hollywood Walk of Fame are trademarks and intellectual property of Hollywood Chamber of Commerce. All Rights Reserved.
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LC-MS Gains Favor Due To the...
Quadruple Helices Appear To Have Role...
Developers of DTC Genetic Testing Are...
Wall Street Decline Takes Its Toll...
Affymetrix negotiated exclusive distribution rights to Almac Group's Xcel™ array microarray, which has been developed for biomarker discovery applications in multiple therapeutic areas including cancer. Xcel array is built around Affymetrix' research-use GeneChip® Human Genome U133 Plus 2.0 array, and is optimized for RNA expression profiling from formalin-fixed paraffin embedded (FFPE) samples. The final Xcel array contains 97,000 transcripts, including all the U133 Plus 2.0 array transcripts, updated RefSeq content, and new content including long non-coding and endogenous antisense transcripts.
"This array represents a significant technology advancement, and combined with Genisphere's Sensation™ reagents, addresses a much-needed FFPE workflow solution for gene-expression profiling and biomarker discovery," comments Kevin Cannon, Ph.D., who heads Affymetrix' expression business. "Researchers now have the ability to carry out retrospective studies for discovery and validation of gene expression biomarkers for translation into clinical practices." The Genisphere Sensation whole transcriptome linear amplification kit is suitable for use with intact, degraded, or FFPE RNA samples.
Almac's diagnostics business offers products and services for the discovery and development of biomarkers, and is developing an in-house pipeline of prognostic and predictive tests and improved cancer diagnostics. The firm's range of services includes exploratory biomarker discovery, verification studies for existing markers, assay development, and biomarker validation.
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"That was definitely his wish," says spokesman Roger Neal. "It's safe to say that wish will be fulfilled."
Monjack, who was found dead Sunday night five months after Murphy died of cardiac arrest, will be laid to rest in a private ceremony Thursday at Forest Lawn Memorial Park in Los Angeles, where his wife was interred Dec. 24.
E! Online was first to report on Monjack's wish to be buried next to Murphy.
Reporting by SARA HAMMEL
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Personal Statement For Graduate School
I need a expert to help me write a personal statement which needs to be on myself and my goals in life.
I can provide all the information. Please open up a chat session so i can give a brief introduction about myself, my goals, and my work experience.
Bonus will be added!
What kind of statement what is your major.


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almaren wrote:
> Is it possible to somehow tell spamassassin to move all messages marked as
> spam directly into the spam/ham/trash folders ?
> The thing is I'm running backups on my mailbox and although I omit
> spam/ham/trash I do collect the mails from my inbox, and in most cases there
> are 40-50 messages with subjects starting with *****SPAM*****. I don't want
> to have theme there.
Spamassassin uses a local delivery agent to do this. We use procmail
and created a recipe ( regex ) that moves all spam messages to the users
spam folder. If you use a local ( not system wide ) setup, then simply
create a filter in the e-mail client.


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|Home Decor
I started quilting in high school when my grandma helped me with a senior project, but my true passion for quilting did not start until about 5 years ago. There is just something to be said about ...
I started quilting in high school when my grandma helped me with a senior project, but my true passion for quilting did not start until about 5 years ago. There is just something to be said about the fact that if I need a new blanket, something warm, something small, something big, something for a picnic ... I can make it myself. I love that feeling and nothing makes me happier than seeing my quilts in use. Love them, abuse them, wear them out .... my quilts are meant for everyday use.Read More » View all patterns by designer (203) »
The fox is a sly little creature who lives in the forest. A fox is quick and sneaky, and oh so cute. This fox won't be able to sneak away from you. He would look great on a quilt, just don't put him near any chickens!
This pdf applique pattern features a cute little fox.
Included in pdf pattern:
- Iron on applique instructions
- Outline drawing of applique with numbering for easy assembly.
- Full color drawing of applique for color reference.
**Bonus** Print the included full color version onto iron-on transfer paper for even more project opportunities!
Use your creativity to make a ton of different projects! This pattern can be used to create a full sized quilt, a nursery wall hanging, or the perfect able runner for your dining room table. Create boutique style kids applique shirts, baby bodysuits, little girls applique dresses, or even aprons. This template would even work great for paper crafts. Make unique cards or use it as a scrapbook template. So many possibilities! You are only limited by your own imagination.
Be sure to check out my store for more fun applique patterns!
These patterns are my own originals. Please do not copy, distribute, or sell this pattern. Any end items made using my pattern may be sold within reason. If it gets to a point where you are using a factory to create the end items from my patterns, please contact me for a commercial license.


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Richard Allison, 49, of Amarillo died Thursday, Feb. 28, 2002.
Mass will be at 11 a.m. today in St. Thomas the Apostle Catholic Church with Monsignor Joseph Tash officiating. Burial will be in Llano Cemetery by Schooler Funeral Home, 4100 S. Georgia St.
Mr. Allison attended high school in Borger and was a 1977 graduate of West Texas State University with a bachelor's degree in business administration.
In 1989 he was named president and chief executive officer of Continental Panhandle Lines. In 1995, he was named secretary-treasurer of Texas Bus Association.
He was elected to the board of directors of the American Bus Association for 1997-1998. In 1999 he was re-elected for a three year term as a member-at-large of the board of directors of Trailways Transportation Systems.
He was active in United Way, was a member of Downtown Kiwanis Club, a past president of Amarillo Convention and Visitors Council and past chairman of Tri-State Fair board of directors. He was most recently employed as head of transportation at Flying Star, a division of Davidson Oil.
Survivors include his wife, Mary; two daughters, Lauren and Andrea, both of Amarillo; his parents, Martha Allison of Borger and Thomas Allison of Amarillo; and a sister, Julie Allison of Amarillo.
The family suggests memorials be to Richard Allison Memorial Fund for the benefit of Lauren and Andrea Allison in care of Amarillo National Bank, Main Bank, P.O. Box 1, Plaza One, Amarillo, TX 79105.
Amarillo Globe-News, March 4, 2002
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AUD/USD Tests London Low 0 commentsMay 14, 2012 10:17 AM | about stocks: FX
The AUDUSD (NYSEARCA:FXA) took out the London morning low at 0.9964 but just barely (low reached 0.9962). The price has bounced up a bit - trading at 0.9971 currently. The 100 bar MA on the 5 minute chart is at 0.9984 and will be eyed as the first upside target should the double bottom, indeed be the bottom for the pair for now.
Taking a look at the hourly chart (see below), the price has some cause for pause at the 0.9952 area . This is a channel support line. Below that the is a steeper channel support line at the 0.9932 level.
With global economic concerns increasing as a result of Greece, Spain, etc, the movement out of risk continue. Commodities, like copper, which tend to correlate with the AUDUSD is also moving lower and is at its lowest level since mid January. This is contributing to the AUDUSD woes.
http://www.forexlive.com/blog/2012/05/14/audusd-tests-london-low/Stocks: FXBack To ForexLive's Instablog HomePage »
Instablogs are blogs which are instantly set up and networked within the Seeking Alpha community. Instablog posts are not selected, edited or screened by Seeking Alpha editors, in contrast to contributors' articles.Full index of posts »
ECB's Constancio: Crisis not over; Constancio, a member of the ECB's managing board, is speaking in Frankfurt. Mar 28, 2012
Best hope for the EUR is an afternoon US equity rebound with European equity markets closing. Mar 6, 2012
Now I've heard everything...Talk swirling that the ECB will lend to the IMF, who in turn, will lend to euro states. Italian yields falling. Nov 17, 2011
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Reviews of this establishment have been flagged and should be considered questionable.
RedPoppy (11) , California | March 5, 2016
beernyc (1) New York, New York | November 4, 2015
I regularly get beers shipped to me in NY. Fred is always my first, usually only, stop. Excellent selection, good prices. He is informative and friendly and is simply the most responsive guy in the business. I typically have my tracking information with the hour. If beer really matters to you, Fred is your guy.
Marheb (376) San Diego, California | June 25, 2015
Bonne sélection, probablement la meilleure de Santee mais lentreposage est pas exactement au même niveau. Trop de produits loin des frigo, température ambiante trop haute à mon goût et des produits passés leur prime. Néanmoins, la possibilité de cueillir un fruits mûr est excellente.
rosenbergh (639) Tampere, Finland | April 26, 2015
First of all Fred is the man! He gave me bottle of KBS for free. Ive been looking for that beer for some time. Fred also likes to talk... and talk about his very impressive beer collection. Beer selection was really great and prices reasonable. What I was missing was 12 oz singles. Definitely a place to visit if youre in the region.
alexlarrivee (1) Quebec | February 23, 2015
Wonderful service by Fred ! Great selection of rare beers and good price for shipping. I recommend to anyone who wants to buy beer online. Give a call at this great bottle shop ! Thank again Fred !
JAC54 (1) California | December 2, 2014
I have bought my last beer from this establishment. Walked in today to buy a bottle of The Abyss and was asked if I was going to buy anything else. When I answered "No" I was told in a very rude tone that I wouldnt be allowed to buy The Abyss. Apparently I wasnt a regular enough customer to warrant such a sale.
stoutnick (7) Brisbane, Australia | May 28, 2014
Fantastic service. Got my package intact all the way over here in Australia. The website is pretty confusing (hence Ambiance score) but apart from that everything else is first rate. Thanks Fred! Will definitely be using this one again.
tgonzal1 (1) , | May 17, 2014
Freddy is awesome to deal with, always offers great selection, great suggestions, and his are on key with the expected prices. Freddy is very prompt with getting orders put together and shipped, with very sturdy packaging to ensure safe travel. Beverages4less is my #1 place to order from online. If there is something you are looking for, give Freddy a call and there is a good chance he has it, even if not listed on website. Highly recommended.
stdaniel (1) North Carolina | April 8, 2014
Ordered online, so n/c on the ambiance. Freddy was awesome to work with, though, and helped me place an order with no problems at all. He even offered suggestions on items that were new and werent listed on the website yet. Shipping was fast and wasnt price gouged. Prices were in line with most other shops Ive seen. Overall, quality shop.
mikesaum (18) Newark , Ohio | March 22, 2014
This place doesnt look that appealing, but it has a pretty good selection of brews. Owner was very nice and helpful, prices seemed on point and werent gouged.


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In the first photo released from the set of the fourth Spider-Man movie, a brooding and intense Andrew Garfield slips into the skin-tight, red and blue Spider-Man costume, officially taking the reins from Tobey Maguire in the popular franchise.
For those who have yet to get to know Garfield, the Los Angeles-born actor, 27, was raised in England and was seen on movie screens recently in The Social Network.
"He has a rare combination of intelligence, wit and humanity. Mark my words, you will love Andrew Garfield as Peter Parker," Spidey 4 director Mark Webb said recently.
– Sara Hammel
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In response to the editorial in the Tribune Chronicle on May 11, so eloquently titled ''Shenanigans ...'' you chose to point out that Trumbull County Highway Engineer Randy Smith hired 14 people who are ''politically connected,'' and included myself, a former Liberty trustee.
Being that I am the only active employee you chose to name, while pointing out that my ''position still exists'' even though ''drilling in Trumbull County has virtually ended,'' I offer the following:
I was recommended to Smith by a three-person panel comprised of representatives from each of the three entities that fund my position - the Trumbull County Township Association; county villages; and the Engineer's Office. They interviewed candidates from a pool of 30 applicants. I was selected and began in January of 2013, not March of 2012 as reported.
As to your statement ''Drilling in Trumbull County has virtually ended, yet the position still exists ...'', it is true drilling has temporally halted in Trumbull County; however, RUMAs (Road Use Maintenance Agreements) are still in place and continue to be sought. Miles of roadway are to be paved this year from drilling pads built last year. Injection well operators are now signing RUMAs and other like agreements with our office due to our persistence with them in protecting the integrity of our roads and bridges.
An agreement for road repairs and improvements was passed by the Trumbull County commissioners on May 21, with FirstEnergy due to line upgrades that have become intrusive on our roadways. This agreement involves 12 miles of roads and bridges.
Pipeline installers who have scheduled work throughout the county also are signing agreements to utilize roads and road rights-of-way. All of the above mentioned items fall under the responsibilities of the RUMA coordinator and will be executed over the next 12 to 18 months.
The industry will determine the future of the position. BP has announced that it will sell its leases to other gas and oil companies, which may decide to drill on some of those parcels.
As for your statement that Smith hired 14 people who were either former political officials or related to political officials, no mention is made of the 24 employees who Smith inherited with political connections, either directly or by family relation, as well as those hired through relatives either currently or formally employed there.
Through Smith's efforts, Trumbull County communities have saved hundreds of thousands of dollars by installing a salt storage facility large enough to store material with all communities; instituting a program to make cold mix asphalt and offering it to all of the same communities, saving $20 a ton; and offering them use of county equipment that most do not possess and employees to operate at only the cost of those employees' wages. Through these efforts as well as his ability and persistence to obtain funds for communities through Issue 1 and other state and federal grants, Trumbull County residents have been well served by his office.
Jack Simon
Simon is the Trumbull County Highway Engineer's Office Road Use Maintenance Agreement coordinator.


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From the Surgery Units, H[[ocirc]]pital Louis Mourier, Colombes (Drs Merad, Yahchouchi, and Hay), Centre Hospitalier Intercommunal, Poissy (Dr Fingerhut), H[[ocirc]]pital Hauterive, Pau (Dr Laborde), and Centre Hospitalier, Montlu[[ccedil]]on (Dr Langlois-Zantain), France.
Only 4 controlled trials have investigated whether prophylactic abdominal drainage was of value after colonic resection. None have been able to find any statistically significant difference, but the number of patients was small and the β error risk was high.
To compare patients who underwent abdominal drainage with those who did not for the rate and severity of complications after elective colonic resection followed immediately by anastomosis of the suprapromontory colon and to compare suction drains with nonsuction drains.
Between September 1990 and June 1995, 319 patients (135 men and 184 women), whose mean age was 67 years (range, 22-95 years), with carcinoma, benign tumors, or colitis, located anywhere between the ascending and sigmoid colons, were included in the study. Patients were comparable for demographic characteristics, except that there were more patients with ascites in the group that did not undergo abdominal drainage (P<.02).
After 2 protocol violations, 156 patients were randomized to the abdominal drainage group and 161 to the no abdominal drainage group. All 317 anastomoses were tested for airtightness intraoperatively and repaired if leakage was found (n=71), and all patients with anastomoses received a routine diatrizoate sodium enema to detect infraclinical leakage.
Main Outcome Measures
The postoperative complications possibly influenced by drainage included (1) deep complications for which drainage can lead to early diagnosis, such as generalized or localized peritonitis, intra-abdominal hemorrhage, or hematoma; (2) complications believed to be enhanced by drainage, such as an operative wound (an abscess, disruption, or incisional hernia) or pulmonary (microatelectasis) and intestinal obstructions; and (3) complications directly due to the drains, such as ulcerations leading to fistulae, hemorrhages, drainage tract infections, difficulty in removal, intra-abdominal retention, and incisional disruptions. Subsidiary end points were the severity of these complications as assessed by the number of related subsequent operations and deaths.
Twenty-six patients overall (8%) had postoperative complications possibly influenced by drainage (9% in the group that underwent abdominal drainage and 8% in the group that did not). This difference was not statistically significant (P<.90). One patient had a fistula directly imputable to drainage. There was no difference between suction and nonsuction drainage (P<.90).
Routine abdominal drainage after colonic resection and immediate anastomosis decreases neither the rate nor the severity of anastomotic leakage. It can, occasionally, be detrimental.
THE COLONIC lumen contains between 108 and 1010 aerobic and anaerobic germs per gram of feces.1 This might explain why postoperative infective complications, the prevalence of which ranges from 10% to 70%,2,3 may be higher in patients undergoing surgery of the colon than in those undergoing any other abdominal surgery. Anastomotic leakage is the leading cause of postoperative infective complications, responsible for 25% to 35% of deaths.4,5 Several procedures have been described to decrease the rate and the severity of postoperative complications, especially infective complications, as well as to decrease anastomotic leakage. These include antibiotic prophylaxis,2 antiseptic mechanical preparation,6 diverting stomas,7 omental wrapping around the anastomosis,8,9 and intraoperative airtightness testing leading to complete anastomotic airtightness integrity.9
The prophylactic drainage of the abdominal cavity was proposed for these same reasons10 in the second half of the 19th century (by Sims11 in 1884 and by Billroth12 in 1881). Prophylactic drainage is thought to (1) decrease the rate of anastomotic leakage by evacuating serosities and blood that, once infected, can lead to abscess formation and opening of the abscess into the anastomosis13; (2) decrease the severity of these complications by earlier diagnosis14; and (3) facilitate the diagnosis of intraperitoneal hemorrhage.13 On the other hand, surgeons who are opposed to drainage believe that it (1) actually stimulates the formation of serous fluid15; (2) can lead to infection from outside16,17; (3) increases the rate of leakage by preventing the mobilization of omentum and adjacent organs, obstructing their sealing action on the anastomotic suture line16,18 or even creating leakage by mechanical erosion of the anastomosis19; and (4) is walled off quickly.20
Four controlled trials21- 24 have found no advantage in favor of abdominal drainage, but the few patients in these trials (range, 51-113) leads to a high β risk precluding any formal conclusions. Moreover, abdominal and pelvic drainage were included in 3 of the trials,21,22,24 whereas no details were provided in the other trial.23 However, abdominal and pelvic drainage differ in that the latter is in the dependent portion of the peritoneal cavity, where (1) the pressure is often negative25; (2) the anterior aspect of the sacrum, once the presacral space, has been opened, is raw, and is without peritoneal cover; and (3) the anastomosis, when low, is infraperitoneal.
Suction drainage may (1) decrease the amount of contamination originating from outside by maintaining negative pressure on the tissues,26 (2) be associated with less postoperative adherence,13 (3) be associated with less anastomotic leakage experimentally,19 and (4) become encapsulated less quickly.20 Suction drainage was used in 1 of the controlled trial,24 while nonsuction drainage was used in the other 3.21- 23 We, therefore, decided to conduct a large, multicenter, prospective study, controlled by randomization, to determine (1) whether prophylactic drainage decreased the rate and the severity of complications eventually related to drainage, after colonic resection followed immediately by intra-abdominal suprapromontory colonic anastomosis; and (2) whether one type of drain (suction or nonsuction) was better than the other.
Between September 1990 and June 1995, 319 patients (135 men and 184 women), whose mean age was 67 years (range, 22-95 years), originating from 15 centers (1 university center, 11 teaching hospitals, and 3 private clinics) participated in the study. Data collection from all centers was completed by June 1995, but all the centers did not enroll in the study at the same time. The number of patients enrolled in this study by each center ranged from 5 to 35 per year.
All patients were aged 18 years or older; there was no upper limit for age. All patients with disease (carcinoma, benign tumors, or colitis) located anywhere along the colon (descending, transverse, or ascending) were eligible to participate in the study, as long as elective resection was immediately followed by intra-abdominal (above or at the level of the sacral promontory) anastomosis. Resection for carcinoma could be for either curative or palliative reasons. Patients undergoing an emergency operation or those with patent infection (abscess and peritonitis) (drainage would be considered as curative rather than prophylactic in these cases), those undergoing resection without immediate anastomosis or with anastomosis in the pelvis (below the sacral promontory), and those undergoing colostomy closure were not included in the study.
The preoperative and intraoperative risk factors were recorded for all patients and are summarized in Table 1.
All patients underwent colonic mechanical preparation, including the administration of laxatives (sennosides) or polyethylene glycol, that included the administration of antiseptic enemas.6 Povidine-iodine6 was used for 80% of these enemas, while hypochlorite27 was used for the remaining 20%; the enemas were administered at 6 PM in the evening and in the morning (3 hours) before surgery. All patients received a 1-dose combination of systemic ceftriaxone sodium and metronidazole at the induction of anesthesia.
The abdominal incision was left to the discretion of the participating surgeon. Ileocolic or colocolic anastomosis could be performed as long as the suture line was located in the abdomen.
The anastomosis could be made with interrupted or continuous sutures, with absorbable or nonabsorbable suture material, in 1 layer, with stapling devices (Gastro Intestinal Anastomosis/Terminal Anastomosis, Autosuture France, Elancourt) for ileocolic anastomoses,28 or with a double-rowed circular stapling device (especially for distal colocolic anastomoses). The anastomosis was protected by omentoplasty or a diverting stoma, according to surgeon preference.
The participating surgeons were asked to test for airtightness9 by looking for bubbles appearing when the colon wall was distended with air injected into the colonic lumen, by a needle inserted through the colon wall between 2 supple intestinal clamps, by fingers placed on either side of ileocolic or colocolic anastomoses, or by means of a balloon-inflated Foley catheter inserted through the anus for distal colocolic anastomoses clamped proximally. If anastomotic leakage was detected, extra sutures were added until complete airtightness was obtained.
After the resection and anastomosis had been performed and tested for airtightness, patients underwent drainage (D+) or they did not undergo drainage (D−), as indicated under the folded upper right corner of a questionnaire rather than the envelope method.29 The randomization order was determined according to random number tables30 with 2 strata, ileocolic and colocolic anastomosis. When patients were placed in D+, they were further randomized to undergo suction or nonsuction drainage. Random assignment was balanced by blocks of 4 in each center. This study was approved by the ethics committee of the coordinating center.
A multiperforated, tubular, 14F polyvinyl chloride catheter was inserted for suction drainage, while a silicon, multitubular, flat drain that wrapped around a 10-mm silicon tube was used for nonsuction drainage. Drains were not placed in contact with the area in which anastomosis was performed, and the distance between the end of the drain and the area in which anastomosis was performed was noted (median, 5 cm; range, 2-10 cm). The drains could exit in either latus, and they were fixed to the skin by sutures. All nonsuction drains were inserted into a colostomy bag, while the suction drains were connected to vacuum bottles emptied 3 to 4 times a day. Nonsuction drains were mobilized and shortened starting on postoperative day 2. All drains were removed on postoperative day 5 at the latest.
The primary end point was the number of patients with 1 or more postoperative complications eventually related to drainage, including (1) Deep complications that were possibly influenced by drainage and for which drainage could lead to early diagnosis, including anastomotic leakage, generalized or localized peritonitis, intra-abdominal hemorrhage, or hematoma. Anastomotic leakage was diagnosed by the egress of fecal fluid through drains, by a subsequent operation or an autopsy (performed routinely for all patients who died during their hospital stay), or by a diatrizoate sodium enema administered routinely close to postoperative day 8 for asymptomatic patients. All radiological images demonstrating less than a perfectly regular and uniform caliber at the level of the anastomosis were considered to be anastomotic leakage.31 (2) Complications possibly enhanced by drainage, including those related to the operative wound (an abscess, disruption, or incisional hernia), pulmonary complications based on evidence of clinical or radiological changes,21,24 and intestinal obstruction.11 Drains are thought to promote infection from outside to within,16,17 are associated with pain-related thoracic complications leading to microatelectasis,21,24 and promote intestinal adhesions.11 (3) Complications directly due to drains, including ulcerations of the gastrointestinal tract tube leading to fistulae,32,33 hemorrhages,34 or infections of the drainage tract35; difficulty in drain removal36; intra-abdominal retention of the whole drain or a part of it36,37; and wound disruption through the drain tract.37 Subsidiary end points were the severity of these complications as assessed by the number of associated subsequent operations and related deaths and extra-abdominal complications.
The postoperative period included the total hospital stay, irrespective of its duration, and the 30 days after discharge from the hospital. All patients were seen on that date because wound (abscesses or incisional hernias) or deep (abscesses, hematomas, and fistulae) complications are known to occur after patients are discharged from the hospital.38
According to the explicative method,30 with a 1-tailed analysis, to decrease the rate of patients with complications from approximately 15%21,24 to 5%,39 with an α risk of .05 and a β risk of .10, 146 patients were required in each group (ie, 292 patients in all).30
Groups were compared with the χ2 test for discrete variables and the Student t test for continuous variables.
Two patients in D− were withdrawn from analysis after random allotment because of protocol violation. Three hundred seventeen patients (161 in D+ and 156 in D−) remained for final analysis.
The 2 groups of patients were comparable for preoperative characteristics, except that there were significantly (P<.02) more patients with ascites in D− (Table 1). Other characteristics, including weight loss (P<.20), use of corticosteroids (P<.10), Crohn disease (P<.30), intraoperative fecal soiling (P<.10), and leakage on testing for airtightness (P<.50), were encountered more frequently in D−, but these differences were not significant. On the other hand, there were fewer patients who underwent omentoplasty (P<.10) in D+. Seven patients whose test results were positive for leakage had extra sutures added until airtightness was obtained, and none of these patients experienced postoperative leakage. Carcinoma was the most frequently encountered disease (found in 70% of the patients) and was resected with curative intent in 83% of the cases (Table 1).
No statistically significant (P<.90) difference was found between D+ and D− for postoperative complications or their severity (Table 2). (1) The overall rate of patients with 1 or more complications was 8.2%. (2) The overall rate of deep complications possibly influenced by drainage was 6.6%. Leakage was detected clinically in 3 patients and radiologically in 1 patient. (3) The overall rate of complications possibly enhanced by drainage was 9.0%. (4) There was 1 complication directly due to drains: an intestinal fistula (1.0%).
Seventeen subsequent operations (5%) were performed, 3 (18%) for anastomotic leakage; 3 of 4 leakages required a subsequent operation. The other reasons for a subsequent operation included hemoperitoneum (n=5), a deep abscess without leakage (n=3), intestinal obstruction (n=2), a wound abscess (n=2), wound disruption (n=1), and acute cholecystitis (n=1).
There were 14 deaths (4%), 7 in each group. Only 1 death was due to anastomotic leakage in D− (ie, 7% of deaths overall). One fourth of the patients with leakage ultimately died. In 5 other patients, the cause of death was intra-abdominal but unrelated to anastomotic leakage, including 2 patients with hepatic failure (1 due to metastases and 1 to cirrhosis), 1 patient with nonresected hepatic metastases who experienced a secondary hemorrhage of the gallbladder bed following cholecystectomy for cholelithiasis, 1 patient with a deep abscess, and 1 patient with acute biliary pancreatic necrosis.
The cause of death in the 8 remaining patients was extra-abdominal, including 3 patients with blood-borne infections secondary to urinary infection, 2 patients with myocardial infarction, 1 patient with respiratory tract failure, 1 patient with a pulmonary embolism, and 1 patient with lower extremity vascular compromise.
The overall rate of other extra-abdominal complications was 4.1%, with no statistical difference between the 2 groups. Irrespective of the type of complications considered, no statistically significant differences were found between suction and nonsuction drains (Table 2).
Prophylactic drainage after elective intra-abdominal suprapromontory anastomosis following colonic resection reduces neither the rate of patients with 1 or more postoperative complications possibly influenced by drainage nor the severity of these complications. There was no difference found between suction and nonsuction drains.
Our study confirms the results of the 4 controlled studies on the use of prophylactic drainage,21- 24 but with greater power (90%) because of the many patients included (n=317), almost the total of the 4 other studies combined (n=326).
Whereas the tendency in the 4 other studies21- 24 seemed to be against drainage, the slight difference (Table 2) in favor of drainage in our series might be due to the many high-risk patients (ie, those with ascites) in D− (Table 1). The complication rates found in our series were similar to those reported in other trials21- 24 regarding (1) the rate of incisional complications, which was 4% compared with 4%23 to 10%21- 24; and (2) the rate of deep abscesses or generalized peritonitis, which was 3% compared with 2%22 and 3%.21
In our series, 1 of 157 patients had a complication directly due to drains, similar to that reported in other controlled trials: 0 of 49 patients,22 1 of 60 patients23 (1 subsequent operation was performed to remove a lost drain), 3 of 94 patients24 (1 difficult drain removal and 2 drainage wound infections), and 1 of 28 patients21 (1 drainage wound infection). Early postoperative intestinal obstruction11 was found in 1 patient in our series, whereas there were none in the other controlled trials.21- 24 On the other hand, nothing can be said about late intestinal obstruction or drainage wound protrusion11 because in our series, as well as in the other controlled series, patients were not observed for longer than 1 month after discharge from the hospital.
In contrast, other complication rates in our study were lower than those reported in the previous trials. Our overall leakage rate was 1.3%, much lower than that of the 4 other series, which ranged from 4% to 21%.21- 24 All of our patients were required to receive a routine diatrizoate enema, as were the patients in the series by Hagmüller et al.23 Two series21,24 required this enema for patients undergoing a colectomy of the descending colon only, thus underestimating the true overall leakage rate in their series. No contrast studies were performed in the remaining trial.22
Explanations for these discrepancies include the following: (1) The absence of emergency operations in our trial, whereas 21% of the patients described in one article24 were operated on emergently, circumstances under which leakage has been reported to occur more frequently.5,40 (2) Eighty percent of our patients received povidone-iodine enemas; these enemas have been shown to significantly decrease the rate of leakage and postoperative infective complications.6 (3) No anastomoses were placed in the pelvis in our series, in contrast with the supraperitoneal,21 infraperitoneal,22,24 and coloanal22,24 anastomoses in other series; these are well known to be prone to higher leakage rates.5,41 (4) In contrast with all the other trials,21- 24 airtightness was tested in all patients; when leaks were found, they were repaired immediately. This test associated with repair has been shown to decrease the final leakage rate.9 (5) In one trial,24 all deep abscesses were routinely attributed to leakage in the absence of contrast studies; therefore, the true leakage rate was overestimated.
Our pulmonary complication rate was 5%, notably less than the rates of 10%24 and 23%21 in 2 series; this rate was not mentioned in the 2 other trials.22,23 These differences might be explained by the fact that the definition of pulmonary complications differed in the literature or by the fact that our fistula rate, known to promote pulmonary complications,21,24 was lower.
The hypothesis concerning the expected difference of 5% between the 2 treatments was not met. Moreover, our overall rate of complications was 8.2% (8.7% and 7.7% in D− and D+, respectively). This 1% difference in favor of drainage is clinically irrelevant; to conduct a clinical trial on the several thousand patients necessary to demonstrate such a small difference would be difficult if not impossible.
The postoperative mortality in our series was 4.4%, which was within the postoperative death rates recorded in the other controlled trials: 3% to 6%.21- 24 Our 0.30% death rate due to anastomotic leakage was lower than the 0.85% to 2.00% rates reported elsewhere.23,24 On the other hand, there were no deaths secondary to anastomotic leakage in 2 of the other series.22,24
To our knowledge, an indication for a subsequent operation has not been used to evaluate the severity of the postoperative course, especially in controlled trials. In these trials, anecdotal complications requiring a subsequent operation included deep hemorrhage,21 anastomotic leakage,22 and removal of abdominal drains23 ; no complications were mentioned by Sagar et al.24
Suction drains have been said to be better than nonsuction drains,25 but, to our knowledge, no controlled intra-abdominal drainage trials have been performed to date, except ours. The only controlled trial42 was conducted after anterior resection, a procedure that was not included in our trial. The results showed that neither type of drainage reduced the amount of collected fluid. The results of our study are in agreement with these data, as no significant difference in outcome was noted according to the type of drain used (Table 2).
Prophylactic abdominal drainage does not seem to be able to improve the postoperative course after elective colonic resection and intra-abdominal anastomosis.
Créteil: Jacques Allouch, MD. Eaubonne: Patrice Baillet, MD. Thonon-les-Bains: Christian Dilin, MD. Poissy: Abe Fingerhut, MD. Romorantin: Henri Hennet, MD. Colombes: Jean-Marie Hay, MD; Yves Flamant, MD; Guy Zeitoun, MD. Corbeil-Essonnes: Gérard Kohlman, MD. Pau: Yves Laborde, MD. Montluçon: Odile Langlois-Zantain. Charenton-le-Pont: Pierre Le Picard, MD. Angers: Gérard Lorimier, MD. Meulan: Simon Msika. Saint-Cloud: Jean-Paul Pujol, MD. Juvisy: François Rouffet, MD. Besançon: Edouard Pelissier, MD
Corresponding author: Abe Fingerhut, MD, Centre Hospitalier Intercommunal, 78303 Poissy Cedex, France (e-mail: email@example.com).
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Boston Lobsters Offering 20% Discount To GMG Readers In Ticket Pre-Sale Offering
For More Info and To Purchase Discount Tickets– http://www.bostonlobsters.net/
For More Info and To Purchase Discount Tickets– http://www.bostonlobsters.net/
Keith Callahan was recently honored as Facility Manager of the Year by the United States Professional Tennis Association (USPTA). Callahan is the General Manager and Managing Partner at Blue Sky Holdings, Inc., the parent company that includes Manchester Athletic Club in Manchester by-the-Sea, MA, MAC Fitness in Rowley, MA, and MAC Fitness in Gloucester, MA. The award was given by the USPTA New England Division at its winter convention held at Chatham Bars Inn Resort and Spa in Chatham, MA November 7-9.
The USPTA's mission is to raise the standards of the tennis profession and promote greater awareness of the sport. Manchester Athletic Club has consistently followed in that tradition. Under Callahan's direction, the club has built a new outdoor tennis venue and home to the Boston Lobsters professional tennis team; fostered a longtime relationship with renowned tennis coach, Nick Bollettieri, and hired USPTA-certified coaches who are supported with continuing education and professional development. The club has also been chosen a USTA Regional Training Center of New England and one of 12 Certified Regional training centers in the country. It is home to MAC Tennis Academy, a tournament-training program for high-performance juniors, as well as a nationally-recognized 10-and-under program that has been producing New England's top players for over a decade. In addition, the club created the MAC Sports Foundation, which provides scholarships to juniors in need as well as grants to community and school programs.
It's an honor to receive this award, said Callahan. I'm blessed to be surrounded by a team of tennis professionals at Manchester Athletic Club who love what they do and strive every day to improve their game, their teaching methods and the quality of our program." Manchester Athletic Club owner, John Donovan, added, "Keith's commitment to excellence reflects the overall attitude here at the MAC to always improve where we can. In tennis, that means we keep learning, by consistently educating not only our players but our coaches as well."
Manchester Athletic Club is a full-service health club and features 12 tennis courts, the Gymazing! Child Center, iXl programs for young teens, a fitness and strength training center staffed with certified professional trainers and nutritionists, indoor aquatics center, multiple group exercise studios, and an outdoor pool with playground.
Keith Callahan of Manchester Athletic Club, recipient of the USPTA's Facility Manager of the Year Award.
GloucesterCast 98 With Craig, Kim, Sista Felicia and Toby Taped 10/19/14
Topics include: Cape Ann Restaurant Week, Franklin Cape Ann,1 Out of 5 Of Us Knew, Lobsta Land, Ohana, Seaport Grille, The Sea Glass Restaurant, Lat 43, The Grand Café At Emerson Inn By The Sea, Mark Lodge Wedding, Destinos, Derek Kaloust, Giuseppe's Closing Poll Results, Indian Food Misconceptions, David Calvo, Anmol, Memory Lane, Who Are The 1%ers That Say We Need Another Pizza Joint?, Lobster Pool Sold, Kim Smith's Apple Crisp, Gloucester Gas Price Website and How I Can't Understand Why Electricity Prices Are Going Up 35% With Lowest Oil Prices In Years, Home Heating and Open Floor Plans, Cape Ann Chimney and Hearth, Curcuru Ciaramitaro Wedding 1938, Captain Joe A Schooner Fisherman, Posture and Fatigue, Elizabeth Bish, Walk Like A Pompous Jerk For Less Back Pain, Treating Back Pain vs Preventing Back Pain, Sista Felicia Cannot Do Yoga Because She Gets Dizzy From Holding In Her Farts, Craig's Obsession With The Alcohol Content In Every Beer He Drinks, A Glass of Wine vs A Glass of Beer, Bill O'Connor Asks- "Is It Up The Line or Down The Line?", Carpooling Today, Tanya Frost Reynolds North Shore Walk For ALS, Joe Borge Sr From Lone Gull Finishes The Ironman In Kona Hawaii, 98th Podcast, Reunion 100th Podcast, Kenny MacCarthy, Manchester Athletic Club New Alliance With Tennis Academy In France, Going Back To Analog Appliances, Today's "Industrial Grade Appliances" Are Made More Poorly Than Yesterday's Consumer Grade Appliances,Thanksgiving Traditions.
Subscribe to Get The GloucesterCast Podcast by Email For Free
Click to Listen to The GMG Podcast On Stitcher Radio On Demand For Free
Lil' Sprouts of Essex Preschool, serving students 2-6 years of age, located at #1 Scott's Way in Essex, MA will partner with the Manchester Athletic Club's program "Gymazing" to create "MAC SPROUTS".
Presently Lil' Sprouts of Essex operates on the public school calendar and is in operation from 7:30 AM to 3:00 PM Monday through Friday. Jane Lindland, Director and owner of Lil' Sprouts of Essex recognizes there is a piece of the community that she could better serve by filling the need for an extended day after school program (3:30 PM – 5:30 PM), as well as coverage during school vacation weeks and full time summer care.
Marcy Plante, Director of Gymazing and an alumni family of Lil' Sprouts of Essex is working hand in hand with Ms. Lindland to develop "MAC SPROUTS" which will begin in September 2014. With this partnership Lil' Sprouts of Essex will bring to their students and families a focus on physical education, health and nutrition. Additional offerings will include instruction in tennis, swim and yoga. Students will be transported from Lil' Sprouts of Essex to the Manchester Athletic Club where families will pick up.
The program will begin with a limited enrollment of 20 students per day. To enroll contact Lil' Sprouts of Essex @ 978-768-6287.
The clever tale of Shelly Oysta – a poor girl who dreams of a better life aboard the glimmering yachts of Cape Ann. Mrs. Fifi Hogenheimer, the créme de la créme of Cape Ann High Society, holds her annual gala to showcase her Tip Top Tiara. Toe-tapping tunes, uprorious laughter, a double wedding and a happy ending will usher Spring in with a bang! Developed through Henry Allen's Young Playwrights Workshop, inspired by the music of Cole Porter and George & Ira Gershwin. Only 6 performances, opening Friday May 2nd!! Advance tickets on sale now at www.NorthShoreFolk.org
Contact Marcy Plante at 978-526-8900 ext 384
or firstname.lastname@example.com 978-526-8900 ext 257
GloucesterCast Taped 12/1/13 With Host Joey Ciaramitaro and Guests Toby Pett and Amandacakes
Topics Include: Family Cookie Day, Turducken, ChromeCast, Downtown Gloucester Ladies Night, The Hive Gift Wrapping Service, Buoy Painting, Lobster Trap Tree, Rockland Maine's Lobster Trap Spike, Favorite Gloucester Breakfasts, Sugar Mag's, Lobster Land, Sailor Stans, Mamie's Kitchen, Charlie's Place, George's Coffee Shop, Willow Rest, Best House Made Hash, West Indian Hash, Reader Subjects, Cruise Ships, Beauport Princess, Thanksgiving Dinner, Turkey Pot Pie, Sista Felicia On Cover Of Cape Ann Magazine, Mariposa, Lowell Peabody Call-Out, New GMG Technical Jackets, Manchester Athletic Club Holiday Fair
Purchase- GMG Caps, Technical Jerseys, Hoodies, Dry Fit Shirts Here- http://gmg.storenvy.com/
Hey Joey,
Long time no see!! Where have you been?
Can you please post the following on GMG? We started an AMAZING Black Friday promo early!!! Zero fees until 2014! No joining fee, the rest of this month for free and the whole month of December! Promotion ends on Cyber Monday- 12/2/13.
Call Samantha Larsen at the MAC at 978-526-8900 and secure the deal for yourself!
See y'all there in January when work slows for me!
MAC Holiday Fair
Friday December 6, 2013
Cocktail Party!
MAC Holiday Fair
Saturday December 7, 2013
Contact Marcy Plante to reserve your table at firstname.lastname@example.com
$40 per table
Tremendous things will be happening at the MAC with Nan at the Helm of The Fitness department- Mark My Words!
Can't wait for lobster season to end so I can get back in there!
Manchester Athletic Club is strengthening its fitness program with leadership from Nan Gorton. Gorton was recently chosen to helm the business' growing Fitness Division, which includes Manchester Athletic Club in Manchester by-the-Sea, MA, MAC Fitness in Rowley, MA and MAC Fitness in Gloucester, MA.
Gorton has been a staple at Manchester Athletic Club for the past seven years as a fitness trainer and co-owner of Hilltop Training, a popular running program among members. Most recently, she launched North Shore Sports Performance Institute (NSSPI), which offers sports performance training to kids 10-18 years old. She comes to the position with a myriad of backgrounds in addition to fitness, including careers as a lawyer and as an Olympic caliber athlete in the sport of women's ice hockey.
The move will bolster the club's already booming fitness department, which includes a ProFitness Program, personal training, TRX, pilates, swimming, basketball, nutrition and wellness, and over 75 group fitness classes—from strength to cardio, indoor cycling, Zumba, mind body, aquatics and Les Mills Body Pump and Body Combat.
"Nan brings a tremendous amount of energy, expertise and creativity to our members and, importantly, to our local community," said Keith Callahan, General Manager and Managing Partner. "With Nan's leadership, we're excited to launch new programs for our members and have already developed a unique program called Commit to Get Fit that will be provided for club members as well as open to the community this fall."
"I have always believed that great success comes from sharing a common goal and working together to make it happen," added Gorton. "I am excited to get to work getting the best out of everyone I work with both as a coach and a manager."
Manchester Athletic Club is a full-service health club featuring 12 tennis courts, the Gymazing! Child Center for preschool-aged children, iXl programs for young teens, a fitness and strength training center staffed with certified professional trainers, indoor aquatics center, multiple group exercise studios, and an outdoor pool with playground.