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Latest: DeNovix Receives Patent for Innovations in Microvolume UV-Vis
Latest: BioCellChallenge Reports Very Promising Results from Its First Intravenous Assay
Latest: NanoTemper Technologies Introduces New Software Packages for Advanced Protein Stability T...
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Latest: Markes Air Monitoring Equipment Ranks Top in Independent US EPA Field Trials
Latest: miVac DNA Concentrator Enhances UK Researchers Forensic Sample Preparation
Latest: Free Webinar - Introduction to FT-IR Spectroscopy: Theory & Applications
How Urbanization of the Water Cycle Is Affecting the Environment
SelectScience® Invests in Today's Scientists to Impact Tomorrow's World
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Amersham™ Typhoon™ Laser Scanners Deliver Sensitive Multimode Biomolecular Imaging
Top Tips for Optimizing Your Centrifuge Performance
Exclusive Liquid Biopsy Video Interviews
Determine Aggregation Propensity with ΔG Trend and the HUNK
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Evaluation of Slow Equilibration Kinetics in Antibody Chemical Denaturation Experiments w...
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Here's another mobile phone related treat, this time from U.S. Cellular. If you don't want to get tied up with a two-year contract from mobile carriers but still want to enjoy calling and data browsing privileges using your phones, prepaid monthly plan is your way to go. U.S. Cellular is offering three new types of these prepaid monthly plans with monthly charges of either $29, $39 and $49. All these prepaid plans come with unlimited messaging choices and graduated levels of included voice minutes.
Let's take a quick rundown of these new U.S. Cellular prepaid plans and the phones suited well for each of them. The $29 Prepaid Plan is perfect for users who text more than make voice calls. It comes with 200 minutes and unlimited text, picture and video messaging. U.S. Cellular is offering this plan with a Samsung Messager Touch, a great texting phone with 2.6-inch QVGA touchscreen and full-slide out keyboard.
Then you have the $39 Prepaid Plan for mobile phone users who mainly text and surf the web. It's loaded with 400 minutes, unlimited text, picture and video messaging plus up to 5GB of web browsing add-on. U.S. Cellular suggests to get this plan with either a Samsung Freeform, Motorola GRASP or LG Mystique.
The last of the new U.S. Cellular prepaid plans will cost your $49 a month and is perfect for users who talk and text a lot. It comes with 1,000 minutes and unlimited text, picture and video messaging. This plan is best availed with the LG Wine or Samsung Profile.
Of course if you don't mind receiving unexpected charges every month you can always opt to get a postpaid plan. U.S. Cellular is also offering two new postpaid plans – the Belief Plans and Essential Plus Family Plan. The former charges you with $69.99 Primary Plus Plan and gives you up to 5GB of data, unlimited text, picture and video messaging plus free GPS navigation. It also comes with unlimited incoming calls from any phone as well as mobile-to-mobile calls. The Essential Plus Family Plan on the other hand charges you $139.99 per month and gives you 1500 share minutes, unlmited messaging and up to 5GB of data.
There you go. Some nice offers from U.S. Cellular which are enough to make you stay online and connected during the Holiday Season. Take your pick now folks.
Read [PR Newswire]

subset: commoncrawl


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The University of Hawaii baseball team lost 3-1 to Long Beach State on Friday night at Les Murakami Stadium.
UH (19-26, 3-13 Big West) lost for the 13th time in its last 14 conference games.
Hawaii's Matt Cooper (4-5) allowed two runs and four hits over eight innings with one walk and six strikeouts.
Andrew Rohrbach (6-1) went the distance in a five-hitter for the Dirt Bags (24-23, 10-6) with nine strikeouts and two walks.


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Action fiction
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Action fiction is a type of genre fiction, that includes physical action of an exciting kind. The phrase "action fiction", as used here, refers to prose fiction and not fiction in other media.
The word "action" also refers to "the events represented in a story or play: the action is set in the country" (New Oxford English Dictionary). And "action" is one of the modes of fiction.
Genre fiction[edit]
Action fiction is a form of genre fiction whose subject matter is characterized by emphasis on exciting action sequences. This does not always mean they exclude character development or story-telling. Action fiction, is related to other forms of fiction, including action films, action games and analogous media in other formats such as manga and anime. It includes martial arts action, extreme sports action, car chases and vehicles, suspense action, and action comedy, with each focusing in more detail on its own type and flavour of action. It is usually possible to tell from the creative style of an action sequence, the emphasis of an entire work, so that, for example, the style of a combat sequence will indicate whether the entire work can be classified as action adventure, or a martial work. Action is mainly defined by a central focus on any kind of exciting movement.
Action as a literary mode[edit]
"Action is the mode fiction writers use to show what is happening at any given moment in the story," states Evan Marshall,[1] who identifies five fiction-writing modes: action, summary, dialogue, feelings/thoughts, and background.[2] Jessica Page Morrell lists six delivery modes for fiction-writing: action, exposition, description, dialogue, summary, and transition.[3] Peter Selgin refers to methods, including action, dialogue, thoughts, summary, scene, and description.[4]
See also[edit]
- ^ (Marshall 1998, p. 142)
- ^ (Marshall 1998, pp. 143–165)
- ^ (Morrell 2006, p. 127)
- ^ (Selgin 2007, p. 38)
- Marshall, Evan (1998). The Marshall Plan for Novel Writing. Cincinnati, OH: Writer's Digest Books. pp. 143–165. ISBN 1-58297-062-9.
- Morrell, Jessica Page (2006). Between the Lines: Master the Subtle Elements of Fiction Writing. Cincinnati, OH: Writer's Digest Books. ISBN 978-1-58297-393-7.
- Rosenfeld, Jordan E. (2008). Make a Scene: Crafting a Powerful Story One Scene at a Time. Cincinnati, OH: Writer's Digest Books. ISBN 978-1-58297-479-8.


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Definition of a Myth
a story or legend, often based on a true event, that tells of the culture, beliefs, events, and important characters in the history of a people. A myth uses exaggeration and symbolism to make the story exciting and meaningful to the listeners and readers.
the "problem" - usually the plot of a myth that involves some type of conflict or problem between teo or more characters, or between the character(s) and some other being force
the means by which the characters solve the conflict; the events that follow the climax and the lesson/moral learned


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2004 Oscar Nominees
reviewed by Steve Sailer
The American Conservative, February 28, 2005
This year's Oscar nominees for Best Picture comprise one of the weaker slates in memory, yet an enormous audience will no doubt tune in February 27 to watch the Academy Awards.
That the public still cares about the Oscars, or films in general, is curious. Now in its second century, going to the movies is almost as old-fashioned as such one-time rivals for the entertainment dollar as vaudeville and brass band concerts. Yet, although the average American spends over 1,600 hours annually watching television, compared to just 13 hours at the movies, they remain at the top of the pop culture food chain.
Popular music strongly challenged cinema for supremacy in the Sixties and Seventies, but has since splintered into micro-styles. In contrast, movies have gotten so expensive that only a few are released each week, allowing the studios' expert marketers to concentrate (albeit briefly) the national attention.
Despite television's pervasiveness, it lacks the prestige of film because, to be frank, as an advertiser-supported medium, TV aims primarily at women. A back-of-an-envelope calculation suggests that American men transfer about one trillion dollars annually to women to spend, so television networks (subscriber-supported HBO excepted) pursue female viewers.
In contrast, males buy the majority of movie tickets, so films cater to them. And, as feminists have been known to complain, in our society (as in all societies), renown accrues mostly to things guys like. Men just care more than women do about constructing vast hierarchies of fame, such as the Oscars.
Although female studio bosses are common today, the Academy Awards are still extraordinarily male-dominated. For example, women have picked up only three of the 385 nominations for Best Director, and (alert Nancy Hopkins!) none at all for Best Cinematographer.
Female screenwriters have become scarcer over time. Frances Marion was the highest paid writer in Hollywood's first two decades, but among the 86 individuals with three or more screenwriting nominations, only eight are women, and just three are from the liberated post-1970 era.
The movies could certainly use an injection of female talent, although 2004 wasn't quite as weak as the Best Picture nominees would suggest. Three of last year's four most impressive directorial achievements failed to win Best Picture or Best Director nods. Zhang Yimou's visually overwhelming "Hero" was ineligible on a technicality. Brad Bird's "The Incredibles" was shunted into the Best Animated Feature category (although he received deserved Best Original Screenplay recognition).
And, of course, the most audacious and triumphant film of 2004, the picture that Quentin Tarantino called "one of the most brilliant visual storytelling movies I've seen since the talkies," Mel Gibson's "The Passion of the Christ" was turned away out of blatant ethno-religious animus. (Gibson is crying all the way to the bank, no doubt.)
These lapses allowed a trio of second-raters to contend for Best Picture. "Finding Neverland," the story of how J.M. Barrie came to write Peter Pan, is a snooze, and the Ray Charles biopic "Ray," starring an inspired Jamie Foxx, is less than the sum of its admittedly formidable parts.
Some readers objected because I broke with the media conspiracy covering up the subject of Clint Eastwood's critically-celebrated, but shallow and manipulative "Million Dollar Baby:" a paean to euthanasia. But I didn't want subscribers unknowingly to encourage attendance by any of their disabled, aged, or infirm loved ones, who might well think they were being advised to hurry up and die.
So, that leaves Alexander Payne's "Sideways" and Martin Scorsese's sympathetic take on Howard Hughes' happier days, "The Aviator." "Sideways" reworks that staple of teen sex comedies, the buddy road trip genre, for grown-ups. It succeeds.
While "Sideways" is an excellent small movie, well worth its $12 million budget, "The Aviator," which cost $112 million, is an excellent huge movie. In basketball, an agile 6-footer always loses to an equally agile 7-footer, and the same deserves to be true in this Best Picture race because "The Aviator" is a blast, almost three hours of quick, intelligent entertainment.
There's even a pro-free market ending, as Hughes quells his growing madness long enough to stop Congress from nationalizing overseas flights and handing a monopoly to his TWA's enemy Pan-Am (led by liberal icons Alec Baldwin and Alan Alda, who are superbly cast as the sleaze-dog villains they were born to play). And, gentlemen, while Leonardo DiCaprio may be insufferably cute, it's time to admit he's an outstanding movie star.
Steve Sailer (www.iSteve.com) is a columnist for VDARE.com and the film critic for The American Conservative.
To read my latest film
reviews, subscribe
to The American Conservative
Steve Sailer's iSteve.com homepage


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Crescent City Jazz Festival in New Orleans
Travel with Harmony & Understanding March 6-9 and experience the "big easy" with all it has to offer during the Crescent City Jazz Festival.
For high school and college-age performance groups providing opportunities to perform for professional New Orleans jazz musicians for critique and in various venues around the city.
We encourage all interested patrons and alumni of Harmony & Understanding to join us for 3 fun-filled days in New Orleans!
- The festival is sponsored by America Classic and the Visitors Bureau of New Orleans.
- All festivities, including lodging, take place in the historical St. charles Hotel on Bourbon Street.
- The package includes: charter bus transportation by Chuck's Travel, 2 nights double occupancy lodging in St. Charles Hotel, Mississippi River Boat Dinner Cruise and free admittance to all Crescent City Jazz Festival events.
- Interested in joining us? Please contact Andrea Trent, Director at 903-510-2213 or email firstname.lastname@example.com.


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Shocker! Although she's featured prominently in the ads, there'll be no Sue Sylvester in 'Glee: The 3D Concert Movie.'
Creator Ryan Murphy dropped the news about cutting Emmy-winning star Jane Lynch's scenes at Saturday's press conference for the film, which opens August 12.
"We're doing another version in a couple of weeks on DVD," he said. "Jane will be on that. We'll do it that way."
Lynch did appear by video on all the tour stops and was at a concert that was filmed for the movie. In the trailers, she warns people not to see the movie: "People, save your money. This thing sucks," she says in typical Sue fashion.
There's also a a standalone Sue ad where she urges fans "Stop Believing," a riff on the show's anthemic cover of the Journey classic "Don't Stop Believin.'
The song list features a cover of My Chemical Romance's 'Sing,' originally covered by Sue Sylvester and New Directions in the Sue-centric 'Comeback' episode. Guess Lea Michele, Cory Monteith and co. will have plenty to sing about without their resident anti-glee coach.
Is it really a 'Glee' movie without Sue?
[via USA Today]
categories Movies


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GIBRALTER ISLAND - A significant harmful algal bloom is forecast for the western basin of Lake Erie this summer.
The forecast was announced by a group of scientists Thursday morning during a news conference hosted by Ohio State University's Stone Lab, a research station near Put-in-Bay.
On a new numbering system which rates blooms on a scale of 1-10, this year's bloom is estimated to be a 5 or 6.
Article Photos
Research scientists Tom Bridgeman of the University of Toledo (from left), Rick Stumpf of NOAA, Justin Chaffin of Stone Lab and Laura Johnson of Heidelberg University answer questions following the algal bloom forecast announcement Thursday morning.
"This does not mean all of western Lake Erie will have a problem," said Rick Stumpf of the National Oceanic and Atmospheric Administration, a nationally known HAB expert. "If (the wind is) calm, there will be places with scum. That is to be expected."
He reviewed the last few years of HABs with 2011's mega-bloom as the baseline to which others are compared.
"2012's forecast was a mild bloom as expected," Stumpf said. "2013 was much worse than we expected."
He said variable factors play a part.
"Temperatures in June and July seem to have a great effect," he said.
And the wind blowing bacteria around makes it seem worse in some areas than others.
The four scientists who compared notes to make the forecast agreed the severity could increase if the rest of July is wet and causes more nutrient runoff from the Sandusky and Maumee rivers.
Much of the forecast is based on data collected by Heidelberg University's National Center for Water Quality Research. Researcher Laura Johnson provided background on the center's data collection methods during her presentation.
"We had some big loading events early in the spring," Johnson said. "Two really big rain events."
During heavy rains, dissolved phosphorous is washed into the Sandusky and Maumee rivers, and eventually into the lake.
According to the four researchers who spoke, dissolved phosphorous is the main cause of HABs in Lake Erie. But other nutrients also play a part, said Justin Chaffin, a Stone Lab scientist studying HABs.


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Verizon discounts the Samsung Galaxy Tab to $499.99
0. phoneArena 03 Jan 2011, 09:23 posted on
Following the footsteps of Best Buy, Verizon is reportedly preparing to slash the price of the Samsung Galaxy Tab to $499.99. Furthermore, this offer comes along with free movie rentals from the Blockbuster app and...
This is a discussion for a news. To read the whole news, click here
posted on 03 Jan 2011, 14:48 0
1. Shafeer (Posts: 79; Member since: 30 Dec 2010)
Value for money.
posted on 04 Jan 2011, 11:45 0
2. jogutier (Posts: 324; Member since: 12 Feb 2010)
I read some where that Verizon lower their price days after Best Buy lowered theirs. Another old article. Thanks PhoneArena!
Comments for : Verizon discounts the Samsung Galaxy Tab to $499.99


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Veteran California roots-rock, hardcore from Italy and improvisational jazz, on a Tuesday night.
Dave and Phil Alvin with the Guilty Ones, Rock n' Bowl, 8 p.m.
A founding father of what they call Americana today, Californian Dave Alvin revved up roots music with punk energy back in the '80s; his band the Blasters, with older brother Phil, was a contemporary of groups like X and Jason & the Scorchers. New Orleans roots-rockers Johnny J and the Hitmen open.
Raw Power, Siberia, 10 p.m.
The Italian hardcore punk band formed over 30 years ago. With Wartorn, the Pallbearers and the Split Lips.
Steve Marquette Quintet, Blue Nile balcony room, 10 p.m.
Free-jazz guitarist Steve Marquette is joined by Open Ears organizer and trombonist Jeff Albert, plus Jesse Morrow, Brad Walker and Marcello Benetti.


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This one is self-explanitory.
Apparently the Washington Nationals' performance on Thursday against the San Diego Padres wasn't exactly up to par, so she decided to entertain herself.
By yanking one of her baby teeth out.
Not exactly high praise for the level of entertainment being provided at Nationals Ball Park.


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Every year, Fast Company publishes a ranking of "The World's 50 Most Innovative Companies." This year's list is hot off the presses. Check out the full list of companies and organizations here. Note the diversity of industry sectors represented — from high tech and entertainment to healthcare and education. As always, Career Services staff can …
Tag Archive: health
Permanent link to this article: http://www.dartmouth.edu/~careerblog/2012/12/want-to-work-for-an-innovative-organization/
TOPICS INCLUDE: CAMPUS CHAPTER LEADERSHIP OPPORTUNITY – Seneca International – DEADLINE: 6/15/12 ONLINE JOURNALISM INTERNSHIP – Great Schools (Summer)(San Francisco) – PAID PROGRAM ASSOCIATE – Peer Health Exchange (Full-Time)(DC) GLOBAL SECRETARIAT INTERN – White Ribbon Alliance (Summer)(DC) – DEADLINE: 5/15/12 MARKETING & COMMUNICATIONS ASSOCIATE – Citymeals-on-Wheels (Entry-Level)(NYC) "58 Quotes to Inspire Leadership, Resilience and Social …
Permanent link to this article: http://www.dartmouth.edu/~careerblog/2012/05/career-blitz-non-profit-common-good-careers-2/
National Wear RED Day – Today! What opportunities does this present?
Today, February 3, 2012 is National Wear Red Day to raise awareness of the prevalence of Heart Disease in women. How many of us know someone who has been affected by this? The statistics show that Heart Disease kills more women that all forms of cancer combined. However, more than raising awareness, there are some great opportunities …
Permanent link to this article: http://www.dartmouth.edu/~careerblog/2012/02/national-wear-red-day-today-what-opportunities-does-this-present/
Non-Profit Careers Digest: January 30th, 2012
NON-PROFIT CAREERS DIGEST: JANUARY 30th, 2012 1. Special Events & Development Intern – Women's Refugee Commission (New York)(Spring) 2. Funding for Unpaid Internships – SPRING 2012 Deadline: 2/1/12; SUMMER 2012 Deadline: 4/25/12 3. Research Coordinator (Entry-Level Job) – Mass. General Hospital (Boston) – DEADLINE: 3/1/12 4. Link Up with LinkedIn.com – Dartmouth College Alumni Group …
Permanent link to this article: http://www.dartmouth.edu/~careerblog/2012/01/non-profit-careers-digest-january-30th-2012/
2012-2013 Global Health Corps Fellowship – DEADLINE: 2/17/2012
2012 – 2013 GLOBAL HEALTH CORPS FELLOWSHIP – DEADLINE: 2/17/2012 Positions are available in Burundi, Malawi, Rwanda, Uganda, Zambia, and the USA. For each placement, two fellows are selected: One in-country fellow (citizen of the placement country), and one international fellow (US citizens for placements in Africa; any non-US citizen for placements in the US). …
Permanent link to this article: http://www.dartmouth.edu/~careerblog/2012/01/2012-2013-global-health-corps-fellowship-deadline-2172012/
DEADLINE TO APPLY : Tuesday, Jan. 10 at 11:59pm – DPCS Post-Grad Fellowships
DEADLINE TO APPLY via DartBoard: Tuesday, January 10 @ 11:59PM DPCS ONE-YEAR POST-GRADUATE FELLOWSHIPS All positions are available in New York, NY Complete job descriptions and application instructions can be found at: http://www.dartmouth.edu/~tucker/funds-grants/dpcs-postgrad/dpcspostgrad.html You may apply for up to 3 of the 7 DPCS Fellowship opportunities below: Middle School Teacher – East Harlem School Project …
Permanent link to this article: http://www.dartmouth.edu/~careerblog/2011/12/deadline-to-apply-tuesday-jan-10-at-1159pm-dpcs-post-grad-fellowships/
Latino Medical Student Association 7th Annual National & 39th Annual Northeast Conference.
February 3 – 5, 2012 Harvard Medical School 25 Shattuck Street Boston, MA 02115 Friday, February 3th: Massachusetts General Hospital Cocktail Reception Saturday, February 4th: Conference Begins! Sunday, February 5th: HOD/National Board Meeting Announcing Keynote Speaker: Dr. Pedro José Greer, Assistant Dean of Academic Affairs and Chair of the Department of Humanities, Health and Society at Florida International University …
Permanent link to this article: http://www.dartmouth.edu/~careerblog/2011/12/latino-medical-student-association-7th-annual-national-39th-annual-northeast-conference/
Research Assistant- Internship Opportunity!
Interested in health and medecine for a career? Apply for a full-time research assistant position at the Hospital for Special Surgery in New York, New York. The research assistant will have the opportunity to study new approaches to thrombosis prevention in patients undergoing joint replacement surgery. The program is interested in the research assistant to begin in January …
Permanent link to this article: http://www.dartmouth.edu/~careerblog/2011/11/research-assistant-internship-opportunity/
Permanent link to this article: http://www.dartmouth.edu/~careerblog/2011/10/non-profit-career-digest-october-6-2011/


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Louis Sylte shows scenes of his logging days.
Photo by Oscar Roloff/Woodinville Weekly.
by Oscar Roloff
When World War II erupted, Louis Sylte rushed down to the local Navy recruiting office to seek enlistment into their construction battalion unit.
When he told them of his extensive backround, the officials said they were only allowed to enlist men as seamen and he was way over-qualified.
He then rushed to Bremerton Naval shipyard and applied for entry as a pipe-fitter and was accepted.
Here he spent four years surrounded by asbestos work. At that time, no one was aware of the asbestos danger. Consequently, today, Louis at 82 is hooked up to an oxygen making machine that is in his bathroom. Nearly 50 feet of rubber hose runs from the machine to Louis to keep him alive. For him it's that way for 24 hours a day.
If he leaves his apartment, he's hooked up to a portable oxygen bottle that's good for two hours, that's all. Thus Louis can't be away too long.
So today he's paying his dues for volunteering for navy yard duty. He receives no disability for that problem.
His parents came from Norway, briefly resided near Sylvania, then settled on the Eastside.
Born in 1913, Louis attended local schools to graduate from high school in 1932 as a star pitcher.
From there, he worked for Siler Logging Company, yet he found time to play semi-pro baseball and set many a record.
He spent many years logging the then-great forests of the Eastside. "The huge area was full of giant trees. One tree was so huge it took us four days to get it down. All we had were plain saws. I used to climb up 80 feet or more to top trees. It was extremely dangerous," the former logger recalled.
As he mentioned the many Eastside loggers he'd worked with and the people he then knew, I said, "I know them all. Years ago I wrote about them." A small world, indeed.
When time permitted, Louis taught square dance lessons to many area people. (Though I used to square dance, he didn't teach me.)
In 1965 Louis bought property on Chinook Pass and built a nice house on it, then retired there in 1974.
"When my breathing became worse, I had to return here to be near my medical facilities," he said, "The place will now go to my son."
After Louis's wife Juanita died of cancer, he remarried; his wife's name is Grace.
What does the ex-logger think of the bulging Eastside? "There's been a tremendous change. Progress will not be stilled. I recall the roads when they were narrow wagon roads. And the three Gisle brothers owned a Stanley Steamer and ran it up and down the roads until the tires gave out. The three were Einar, Oscar, and Sid. They had two twin sisters," Louis recalled.
I remember one of the Gisle women, wrote about her. In fact, I've been in their old log cabin home. Probably now demolished.
"I've had a good life," Louis concluded.


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No matter where you live, India, Pakistan, Philippines, China, Africa, Europe, America or in any country you can become an Air Hostess. The job of an Air Hostess can have you traveling around the world. This exciting flying job will have you flying with a first class attitude, staying in the finest hotels, meeting different people and lots of excitement.
What does it take to be an air hostess?
One of the important aspects of travel by air is concerned with making the journey of the passenger as much comfortable and safe. It is in this respect the Air hostess/Pursers play their role. With the adoption of 'open sky policy', career alternatives in the civil aviation sector with the vision of a smart, efficient lady in mind.
Many young girls opt for the career because of the exciting experience of flying, visiting different places, interacting with different kinds of people on board and for the very attractive pay package. This is a highly demanding job which requires a lot of patience, a strong conviction, commitment and hard work for learning the technical aspects of aircraft operation and skills to manage difficult situation.
Eligibility: A simple 10+2 pass certificate (12 years of formal education with pass certificates) or a Graduation degree preferably in Hotel Management or Tourism is required to get enrolled for a short term Air Hostess Diploma Course. Moreover the candidate must also be 17-25 years of age and at least 154.5-157.5 cms tall, unmarried, not obese and have a perfect vision. Fluency in written and spoken English and also in another language is an asset. After the initial screening of applicants is completed the airline company calls them for a written examination, usually of the objective type. Those who qualify in the written examination have to appear for a group discussion followed by a personal interview of successful candidates
Personality Traits: The candidates should have a pleasing personality, charming looks, a good degree of common sense, patience, soft spoken, having interpersonal skills, ability to work in a team environment, adaptable and a lot of zeal and enthusiasm to work in all conditions.
Job Profile: The duty hours are dependent on the flight timings and also upon the flight duration. Air hostess have to welcome the passengers with smile, help them to find out their seat, fasten their seat belt teach the safety rules and regulations for safe flying, providing the passengers with snacks, beverages, pillows and blankets ,making the necessary announcement in the flight, and also to ensure comfort to the passengers . Apart from this the Air hostesses are trained for using the first aid, which helps to deal with injuries.
Remuneration: The AirHostess job gets a lucrative remuneration which can be around US $40,000. However, with experience, you can earn up to US $60,000 annually. The salary for fresh air hostess can be anything between US $16,000 to US $22,000. In India a fresher may earn anywhere between 16,000 and 30,000 Rupees. A Head Flight attendant may earn up to 70,000 Rupees in the domestic aviation sector. However, working with foreign airlines may prove to be lucrative. Reputed international airliners pay an average of nearly 1.5 Lac Rupees with senior Air-Hostesses getting above 3 Lac Rupees apart from lucrative perks and packages. Example: A kingfisher airlines pays between Rs 50,000- Rs 70,000 in the domestic sector and in Emirates A tax free starting salary of AED 3,640 (approx US$ 1,000) plus flying pay of approximately US$ 600 per month Is offered. Besides the salary there are several lucrative perks such as grooming allowance, medical allowance, housing allowance ,uniform allowance, free home pick and drop and so on.
Career Prospects: The career as an air hostess is truly a rewarding one. However, only those with a keen interest to become an air hostess will succeed in this glamorous career. Apart from excellent perks and remuneration, it is full of wonderful trips to exciting destinations. An Air-Hostess may climb the career ladder to become Head Flight attendant and also move alternatively to Ground Staff services.
Please read the answers to the questions in comments. Some readers are asking the same questions without checking for the replies to previous comments. The same questions are likely to be resolved with the same replies. All airlines are recruiting directly from applicants who write in. This website cannot give you the jobs directly. Please write to the airlines. They may even offer alternative job offers if they require manpower. They recruit during the whole year. The airline which does not hire immediately may place your application in the waiting list. All the best, and good luck, to our readers, who are aspiring air hostesses.
Incoming search terms:
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Warrior challenge
More than 100 brave 11 obstacles to raise money for good causes
April 9, 2013
Some people may have enjoyed Sunday by going on a jog around the block. About 100 others, however, took part in Lycoming College's first Warrior Extreme Challenge, where participants tackled a 1....
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Victoria University has welcomed international students for over one hundred years and today it is truly an international University. This year, over 400 students from over 20 countries have chosen Victoria University as their destination to pursue their studies. Our aim is to provide a high quality education along with a personally enriching life experience in a culturally diverse environment. President Gooch has made international study a priority offering bursaries and scholarships to students.
As coordinator for International Student Life and Study Abroad this office will provide support and advice to international students who are studying at Victoria and also Victoria students who are interested in pursuing study abroad.


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It was a case of the script being written before a ball was kicked as the manager decided a game at home against a team well below us who haven't beaten us in years somehow equated to a right hand side comprising a useless Woodgate and a struggling Shotton.
Taking points away from home is starting to become a welcome habit for us of late, could it be that the manager has finally found a way of playing that will put a smile on the faces of our travelling contingent or is it just a case of fine margins?
Apologies to my regular readers for the radio silence, a mixture of family commitments and illness put a stop to any updates over the festive period but I'm back now and looking forward to an exciting second half of the season.
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The fat in my diet has really helped with appetite suppression and satiation, I use to fear fat. I swore I wouldn't touch butter again, but I gorged on sugary cereal and enormous bowls of pasta. I've actually lost weight doing Primal (was in recovery prior to PB) and I'm leaning out! I don't feel weak and I can see some definition around my stomach and my arms and legs feel more toned.
The whole carb thing is debatable, but based on my observations and reading the experiences of others, younger people need the carbs and glucose and lower carb is inefficient. Experimenting is key.


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A group of 17 teenage Israeli singers has been sampling fried chicken and singing for Children's Hospital patients and inner-city youth campers at the YWCA this week as part of a cultural program that brought them to Alabama from the Holy Land.
The Young Rosh Ha'ayiners are being hosted by the Birmingham Jewish Federation and taking part in programs to highlight Birmingham's sister-city relationship with Rosh Ha'ayin, Israel, a city of more than 30,000 people just outside Tel Aviv.
The teens will perform a free, public concert at the Levite Jewish Community Center tonight at 8:45.
"They want to share their culture and express what Israel means to them," said Nancy Denney, one of the Federation hosts.
On Thursday morning, the Israeli teens sang in Hebrew and danced for children taking part in the YWCA summer camp.
Chazmyn Hudson, 9, a fourth-grader at Hudson Elementary School, listened intently as the group sang a Hebrew version of "Do-Re-Mi" a cappella, then ran up and began hugging the Israelis before they left.
"They were awesome," she said.
The group of 15 girls and two boys, ranging in age from 13 to 18, leave on Sunday. They arrived in Birmingham on Wednesday and were greeted at a welcoming dinner at Max's Deli that featured Southern cuisine.
When Birmingham Jewish leaders led a prayer in Hebrew before the meal, Nitzan Schezinger,15, found the Southern dialect amusing.
"With an accent," she said. "It's funny when people speak Hebrew who are not Israelis."
Schezinger, Michal Gaon, 14, and Lee Miri Kaplan, 15, all ate fried chicken.
"In Israel it's not so common," said May Vizel, 17, who passed on the fried chicken and ate a hamburger instead.
"We do have KFC," said chaperone Sigal Shalev, who accompanied the group from Rosh Ha'ayin.
Israeli teens join the army at 18, and three of the singers are scheduled to be inducted within the next year. "They all will eventually go to the army," said Donna Schiff, one of the Federation hosts for the visit.
"Israel is a very small country surrounded by enemies who want to destroy us and we have to struggle for our survival," said Shalev. "It's a very difficult struggle."
One of the singers, Lior Mor, 17, said she turns 18 in December and will report to the army in February. She has already undergone physical and academic placement tests for military service.
"I am looking forward to it," she said. "It's a part of our lives."
Israeli teens sing, share their culture in Birmingham
Greg Garrison | email@example.com By
Email the author | Follow on Twitter
on July 24, 2010 at 8:00 AM, updated July 24, 2010 at 8:15 PM
Email the author | Follow on Twitter
on July 24, 2010 at 8:00 AM, updated July 24, 2010 at 8:15 PM


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Johns Hopkins' Dr. Ben Carson is known around the world for his groundbreaking work as a pediatric neurosurgeon.
But he's become a sought-after speaker for conservatives after his headline-grabbing speech at the National Prayer Breakfast.
After proclaiming Jesus Christ as his role model, Carson applied biblical principles to America's policies on taxes, education, and health care reform -- all while sitting just inches from the commander in chief.
Carson is a featured speaker at the Conservative Political Action Conference in Washington, D.C., which starts Thursday.
He talked more about his views on health care and other issues, on "The 700 Club," March 14.
"Here's my solution," he told the prayer breakfast audience. "When a person is born, give them a birth certificate, an electronic medical record and a health savings account to which money can be contributed pre-tax from the time you're born until the time you die."
"When you die, you can pass it on to your family members so that when you're 80 years old and you've got 10 diseases, you're not trying to spend up everything," he continued. "You're happy to pass it on and there's nobody talking about death panels."
Carson said he continually thinks about the problems facing the United States and believes political correctness is muzzling the American guarantee of free expression and speech.
"It puts a muzzle on them and at the same time keeps people from discussing important issues while the fabric of this society is being changed," he said.
Carson said it's a shame more doctors aren't involved in government, leaving some wondering if this successful neurosurgeon has future plans for political office.
Dr. Carson: Prayer Breakfast Address 'Not Political'
Dr. Carson Prayer Breakfast Speech Generates Buzz
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Find peace with God, discover more about God or send us your prayer request.
Call The 700 Club Prayer Center at 1 (800) 823-6053, 24 hours a day.
A caring friend will be there to pray with you in your time of need.
CBN News White House Correspondent
Jennifer Wishon is the White House correspondent for CBN News based in the network's Washington, D.C. Bureau. Before taking over the White House beat, Jennifer covered Capitol Hill and other national news, from the economy to the 2010 oil spill in the Gulf of Mexico. Follow Jennifer on Twitter @JenniferWishon and "like" her at Facebook.com/JennWishon.
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For 38 years, visitors to the drive-through safari at Six Flags Great Adventure in Jackson would encounter wild animals up close and personal — sometimes too close, and way too personal.
Visitors would drive their own vehicles into the park's wildlife sanctuary, and often times, that vehicle would become a play thing for the monkeys and a feeding box for the giraffes.
This is the way guests visited the safari since it opened in 1974. That is, until now.
On Memorial Day weekend, Great Adventure fired up a fleet of brand new, open-air, five-ton Army trucks for the opening of its newest attraction, Six Flags Safari Off Road Adventure.
These trucks will carry visitors into a 350-acre wildlife reserve boasting approximately 1,200 animals from six continents including elephants, rhinos, bears, lions, tigers, kangaroos and very friendly giraffes.
"The new Off Road Adventure will deliver an experience very close to one you would receive on a real African safari without traveling halfway around the globe to do it," said John Fitzgerald, park president. "This is the beginning of a whole new and greater adventure."
The new safari ride features video tour hosts, the Wild family — Damon, the family patriarch, conservationist and the driving force behind the safari; Tess, Damon's wife and chief veterinarian; and their children, Haley, 12, and Luke, 9.
Throughout the journey, members of the Wild family tell stories and relay facts about the safari and animals who live there.
In addition to the video, each vehicle has its own tour guide who also provide facts, tips and answer questions about the safari.
However, Bill Rives, safari director and chief veterinarian, said the animals are always the stars of the show.
"Our guest go wherever the animals go — even if that is in the middle of a pond," Rives said. "The trucks can go anywhere — through ponds or over hills. The safari is vast and the animals have plenty of room to roam, so each journey will be different."
Rives said that because of the new format and the safari trucks' ability to go "off-road," guest are "guaranteed to see an incredible array of animals, and in some cases, eye to eye."
Included in the new Safari Off Road Adventure is a stop at the new Camp Aventura where guests can disembark the safari truck and visit smaller animals, exotic birds, unusual reptiles and a two-toed sloth named Chewy.
There is also a raised platform at Camp Aventura where guests can hand feed the giraffes for an additional fee, and view a variety of animals in their natural habitat.
Rives said Camp Aventura is a new way for Six Flags to feature smaller animals in the safari.
"Our whole goal is for you to see the animals," Rives said.
Fitzgerald said he is thrilled to begin this new chapter for Six Flags Great Adventure.
"Safari Off Road Adventure combines the beauty and majesty of the world's most exotic animals with a thrilling, off-road truck expedition," he said. "This VIP-style experience cannot be matched anywhere in the world."
The new Safari Off Road Adventure is included in regular park admission.
For more information, visit www.sixflags.com/greatadventure.


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Our news partners at the Wauwatosa Patch report that a 31-year-old Milwaukee man has been arrested for making a bomb threat at a Wauwatosa senior living center Thursday.
Emergency personnel responded to Camillus Court East, 10100 Blue Mound Road, at 7:53 a.m. on a report of numerous phoned in bomb threats.
An employee at the center told police she recognized the voice of the person calling in the threats.
To read the full article from the Wauwatosa Patch, click here.


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AM Journal of Art and Media Studies no. 7/2015 – Call for article contributionLocation: University of Arts in Belgrade, SerbiaPublisher: Orion Art, BelgradeDeadline for abstracts: December 1, 2014Deadline for finalized contributions: April 1, 2015
The Editorial board of AM Journal of Art and Media Studies invites all potential contributors to send in their proposals on the subject of Art and Politics: Agency, Autonomy, Emancipation.
After the end of Soviet hegemony and the fall of socialist regimes in Central and South-Eastern Europe, the consideration of relationship between art and politics seems to be urgent. The experience of more than two decades of political and structural changes towards the development of institutions of global capital also contributes to its urgency. The debate over the (political) nature of art becomes necessary, taking into account that this question has been superseded by a marketplace in which all designations and forms of an Art are available. It shows (itself) to be the best vehicle for manipulation and instrumentalisation towards the current doxa that "everything is possible". Moreover, the issue on political aspect of art has been complicated by the virtue of dominant intellectual opinion and denunciations that all forms of utopian and social dimensions of art, as in the case of revolutionary and emancipatory perspectives of avant-gardes, are responsible for totalitarian and terrorist horror. The aim of this issue therefore is to address the question of how to constitute and affirm an active Art today without slipping into essentialism.
Writing on art and politics from a theoretical perspective involves engaging with different perspectives – philosophy, art, politics, and their conjunctions within the present global situation. Considering this, the editorial board of AM Journal invites the potential contributors to dedicate themselves to reflecting on several proposed vectors:- Art, Politics and Agency questions the modes and possibilities of an articulation of protest and human strike through an Art today stressing the term an Agency and taking into account its relational terms such as s/Subject, singularity, becoming etc.- Art, Politics and Autonomy aims to address the question of the meaning of political autonomy, collectivity, autonomy as restriction, disobedience through Art etc. with regard to present state of affairs.- Art, Politics and Emancipation examines the potentiality of social change through an Art, the possible modes of its refusing to play the role of the victim and circulation of masochism, and abolishing of the active/passive dichotomy, etc.
Please submit your paper topic, abstract up to 250 words, and your short biography to the e-mail address firstname.lastname@example.com until 1 December 2014, and the final version of your paper until 1 April 2015 at latest.
You will be notified until 10 December 2014 if your topic has been accepted.
More about the AM Journal of Art and Media Studies:http://artandmediajournal.wordpress.com/
Looking forward to our cooperation,Editorial Board of the Journal of Art and Media Studies


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In article
, Alan Sherman wrote:
> What is extra for the 100 (180USD)?
> I see that the Palm has double the memory, anything else?
The T5 has built-in flash memory, so if the batteries die the data
isn't lost. Personlly, I back mine up to a flash card on a scheduled
basis and don't worry much. The T5 can also act as a USB hard drive;
the Zodiac can with something like Card Export, too, though.
Perhaps there's something else, too. The T5 might have a more
comfortable form factor for some things, I dunno.
Ray Ingles (313) 227-2317
It's funny how, when it's an economic issue, it's all "We are fifty
sovereign states" but when it's a (so-called) moral issue, all of a
sudden we are one nation. - Bernard HP Gilroy


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This work investigates some of the quantities indicating the degree of robustness of a dynamical system; all intrinsically have ties with the sensitivity of the eigenvalues. The emphasis is put on the computation of these quantities rather than further analysis of their effectiveness in indicating the robustness. The algorithms devised benefit from equivalent singular-value or eigenvalue optimization characterizations. The difficulty that we attempt to overcome is the nonconvex nature of these optimization problems. Surprisingly the global extrema of these nonconvex problems are located reliably and with a decent amount of work (usually by means of a fast converging algorithm with a cubic cost at each iteration) by the help of structured eigenvalue solvers and iterative eigenvalue solvers.
Emre, Mengi.
Emre Mengi received his Ph.D. from Courant Institute, New York University in 2006. He held an S.E.W. assistant professorship position at UC San Diego before joining to Koc University in Istanbul, where he is currently an assistant professor in mathematics. Emre Mengi's research concerns numerical optimization and perturbation theory of eigenvalues.


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Almost immediately after rounding first base, Evan Nagy became a target. His Loyalsock teammates sprinted forward and tackled the big shortstop and a dog pile ensued on top of the first-base bag.
It was a near replay of the scene that unfolded last year, when Bailey Young hit a walk-off single and lifted the Loyalsock high school team to a 5-4 state championship win over Beaver. All the Loyalsock players who competed Thursday at Short Park know all about those high school players who repeated as state champions last month.
And they are showing they are pretty good at this championship thing too.
Article Photos
Loyalsock players celebrate their victory over East Lycoming to win the District 12 Junior Baseball championship Thursday at Short Park. View additional photos at cu.sungazette.com.
Nagy went 3 for 4, Dylan Armson homered and 10 players combined for 16 hits as Loyalsock defeated East Lycoming 15-5 in six innings and captured the District 12 Junior Baseball championship. This Junior all-star team features players who have won prior district, section and state titles at every level and they made a big statement in districts, outscoring three teams, 48-10.
"The Loyalsock High School team has been an inspiration to these kids and Coach (Jeremy) Eck helps them and comes to watch them play so they basically feel like they are auditioning," Loyalsock coach Rich Holz said. "It's nice to have the support of the high school and these kids know they are part of something special at Loyalsock right now."
Loyalsock advanced to next week's Section 3 tournament which it will host at Short Park starting Wednesday. Loyalsock plays its first game Thursday against the winner of Wednesday's Berwick/Athens game.
If Loyalsock builds off what it achieved during districts it could be tough to beat. Loyalsock won all three games by at least 10 runs and fought off a tough East Lycoming challenge last night, scoring nine runs in its final two at-bats after East Lycoming had pulled within 6-5. East Lycoming led 3-2 in the third inning before pinch-hitter Brennan Karney hit a two-out RBI single. Loyalsock scored three runs in the fourth inning, taking a 6-3 lead it never relinquished.
Eight starters delivered at least one hit each and reserves Karney and Zac Haefner went a combined 2 for 2 with two walks. The only two players who did not get hits both scored runs. Winning pitcher Logan Edmonds, Chase McNulty, Eric Holz and Brock Hepler each had two hits while showing the lineup is as deep as it is explosive.
"These kids have had a lot of success and they are a confident group. They are one of the best hitting teams we've had," Holz said. "Hughesville is a great team and we knew it was going to be a tough game and we know what these kids have inside them when the going gets tough."
East Lycoming won two straight games after losing to Loyalsock last Sunday and made Loyalsock earn its championship the hard way. East Lycoming collected six hits in the first three innings, scoring twice in the third on Jared Snyder's sacrifice fly to deep center field and Braden Foresman's RBI walk to take a 3-2 lead. Snyder had a big night, going 2 for 3 with four RBIs and his two-run fifth-inning home run made it 6-5.
After 15 years, East Lycoming coach Kevin Balliet coached his last Little League game Thursday. His team made it a good one, though, putting a scare into Loyalsock.
"I love this group of kids and the way they play together," Balliet said. "They made my last game special. Loyalsock plays with a lot of class and it's a good rivalry. It's been a long 15 years but there have been a lot of good memories."
East Lycoming pitcher Mike Hill has thrown well against Loyalsock in the past and kept his team in the game, throwing four solid innings. East Lycoming also delivered eight hits. Noah Green and Matt Myers each had two hits and five different players scored runs.
Lost in all the offense was two huge throws by Holz, Loyalsock's catcher, in the first two innings. Both times he threw out a runner trying to steal second on a first and third play for the final out, preventing East Lycoming from potentially taking a bigger early lead.
"They beat us pretty bad Sunday but the kids rebounded and played well together," Balliet said. "We gave them something to think about."
Loyalsock started breaking open the game in the fifth inning, scoring six runs on six hits and taking a 12-5 lead. Haefner hit an RBI double, McNulty slammed a two-run single and Holz and Mitch Klingerman capped the rally with RBI singles.
Loyalsock made it three straight mercy-rule wins an inning later as the game's final four batters reached base. Edmonds and McNulty hit RBI doubles before Nagy ripped the walk-off single and set off the celebration.
"It's nice to get this group together. We know everyone can contribute," Holz said. "The tough part is watching kids sit on the bench because they are all good. They are all hitters and they all wait for their chance."
East Lycoming102 020-5 8 2
Loyalsock021 363-15 16 2
Mike Hill, Jared Snyder (5) and Snyder, Brit Balliet (5). Evan Nagy, Logan Edmonds (4) and Eric Holz, Brock Hepler (4). W-Edmonds. L-Hill.
Top EL hitters: Noah Green 2-4, R; Matt Myers 2-4, R; Balliet 1-3, BB, R; Snyder 2-3, HR, 4 RBI, R; Zane Gee 1-2. Top Loyalsock hitters: Edmonds 2-5, 2B, RBI, 2 R; Chase McNulty 2-3, 2B, 3 RBI, 2 R; Nagy 3-4, 2 RBI, 2 R; Holz 2-4, RBI, R; Brennan Karney 1-1, RBI; Dylan Armson 1-2, HR, 2 RBI; Hepler 2-4, 2 R; Zach Haefner 1-1, 2B, 2 BBs, RBI; Anthony Pastore 1-1, 3 R.
Records: Loyalsock 3-0. East Lycoming 3-2.


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6 Words Advertisers Love (That Don't Mean A Damn Thing)
Dermatologist Developed!
If you look at the label of most skin products, it will boast that it was developed by dermatologists. No shit? You're selling a complicated combination of chemicals designed to rub on the skin, and at one point you consulted a skin scientist? I'm worried you felt the need to bring that up. Was your first attempt at hand lotion something a janitor found in his bathtub after a cleaning supply fight?
From now on, save yourself some trouble and only tell us who made your product if it's not obvious, like if a school teacher(!) made your cold medicine or if actor Paul Newman made your salad dressing. When a lotion company advertises that it hired a dermatologist, that's like an airline advertising that it hired a real pilot. Duh, Lubriderm. I fucking went to sixth grade. If you really wanted to give your consumers useful information, you'd tell them how long your product takes to transform from lubricant into paste during masturbation. And even then, my response would be the same: Duh, Lubriderm. I fucking went to sixth grade.
From a Non-Insane Source!
A lot of products brag that they come from a specific source. For example, almost all orange juice excitedly claims to be from California or Florida. And while those states sound mouth-watering, they also happen to produce 95% of all our oranges. So hooray, your oranges came from one of the two places oranges come from. If you really want to impress me, find me some that you grew in Detroit.
Domino's Pizza has an entire ad campaign where they reveal to startled focus groups that their tomatoes come from tomato farms and their cheese comes from cows. Are we really that cynical that we thought evil pizza technicians were growing crops without sunshine and turning spiders into milk? Of course you bought your tomatoes from a tomato farmer, Domino's-- that's like the fucking whole point of that guy's life. And I assume it's cheaper to do it that way than to develop some kind of sinister cloned tomatoes in a moon lab. We're all glad you're not wizards, Domino's, but it's kind of a dick move to assume we were crazy enough to think you were to begin with.
Hey, Domino's, if you have to start an entire ad campaign to convince us that you use food in your food, maybe you should stop and think about how an entire consumer market was convinced that your sauce was made of pressed tampons and burned tires in the first place. Yes, I understand that with each of your pizzas we buy, we make it more and more clear that we know nothing about nutrition and flavor. Still, we know where tomatoes and milk come from. That's not the problem. The problem is that by the time these ingredients get to our front door they also have toenails and a condom in them.
Less Fat, Asterisk!
Sometimes instead of declaring itself to have no fat, a product might brag that it has less fat. For example, Reduced Fat Jif has 25% less fat than regular Jif. Great job. So does a 3/4 full jar of fat. If you look at the nutritional information on reduced fat peanut butter, it just says, "It's too late to care now, so scream the word 'doctor.' Your dumb ass is about to have a heart attack."
Replacing 25% of your fat intake with maltodextrin is about as health conscious as finding a prostitute with a fake leg. Hilariously, if you look at a jar of regular Jif, its selling point is "Yes, Still 18 Ounces!" which really loses its impact when it's on a shelf with 30 other brands of 18 ounce peanut butter jars and right above and below it are different sized jars of Jif. The word "nothing!" would actually make this retarded peanut butter's point in 9 fewer letters.
Some products don't even make it clear what they have less fat than. A York Peppermint Patty claims "As Always... 70% Less Fat!" Cool! I'll cancel my situps! But after searching the bag for actual context, I found that their 70% less fat is 70% less fat than "the average of the leading chocolate candy brands*." No fucking shit, York Peppermint Patty. I kind of figured toothpaste had fewer calories than nougat.
Still curious, I searched for the other end of that asterisk and saw, "*3 grams of fat per 41 gram serving vs. 11 grams of fat in the average of the leading chocolate candy brands." I'm not a mathematician, but those leading candy brands are more than 25% pure fat. Do you want a medal for defeating that? If those figures described a man, nutritionists would categorize him as "obese," and he'd be so easy to defeat that you'd have to give a discount to the billionaires hunting him. Oh, were the stakes not made clear to you, York Peppermint Patty? This hunt started five minutes ago and the dogs can smell your refreshing mint sensation from 14 miles away.
I suggest you run.
Seanbaby invented being funny on the Internet when he made Seanbaby.com. You can follow him on Twitter or face him on Facebook.
For more words you didn't realize are screwing you, check out 9 Words That Don't Mean What You Think or read DOB's look at 6 Words That Need to Be Banned From the English Language.


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Spots in the Sacramento Valley will stay sunny and warm with highs peaking in the upper 80s and lower 90s Monday.
Over the weekend, Sacramento enjoyed a high of 90, which is just around average for this time of year.
The edge of a northern weather system might cool temperatures down on Tuesday and stir up winds in the Sierra. The drop in temps will also be associated with stronger onshore winds.
Sacramento could see conditions dip into the low 80s by Tuesday.


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BiographyI am a 16 year old wiccan living in the USA. I am of the OOTF if that makes any sense to you i would like to talk to you. I love cats kitens and all other felines. Rather stereotypical of me I'll admit. I have a black cat named Chade as well as a stripe named Midjet becouse she is realy small.
Interestsfighting with any kind of weopon, playing games and draying are my primary interests my faverite game is gun for gamecube
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on 1 Jan, 1970
Daniel Day-Lewis – who won a Leading Actor BAFTA last night – loves Marion Cotillard:
Out of the four, it was Cotillard's that took most by surprise.
"It has been the most incredible adventure," said the 32-year-old in an emotional speech. "I loved very single second."
Collecting his prize, Daniel Day-Lewis paid his own tribute to the French star.
"Never mind all the other qualities in her astonishing performance," he said. "For sheer balls alone, I feel Marion should have this award as well."
From BBC Press Release
2 Responses to "Daniel Day-Lewis"
This amazing actor is the classiest act ever. Almost better than the award…
Another one which made my pessimistic self hope a bit :
[when asked who he expects to hand the Oscar to in 2008]: "Marion Cotillard! Did you not see her in 'La Vie En Rose?' She's transforming! That's it!" – Forest WhitakerFeb 12, 08 at 9:46 pm
Fabulous updates! You always do such a nice job. All of your efforts are sooo appreciated.
Thanks!Feb 14, 08 at 5:31 pm


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Snowboarding Forum - Snowboard Enthusiast Forums (http://www.snowboardingforum.com/forum.php)
- Boards (http://www.snowboardingforum.com/boards/)
- - TRice vs Cobra vs Custom vs... Been out of the game for a while (http://www.snowboardingforum.com/boards/51336-trice-vs-cobra-vs-custom-vs.html)
TRice vs Cobra vs Custom vs... Been out of the game for a while
Im from the good snow of the Rocky Mountains but been living out East for a while and thus out of the game for quite some time. Last board: Burton Custom 7 years ago. Needless to say, could use some recs
I enjoy riding steep chutes, through the trees, all-mountain type of riding. I dont do much of the park and only the occasional jumps and slightly more often cliffs.
Im looking at Lib Tech T Rice, the Never Summer Cobra or the always dependable Burton Custom again (although Id like to switch it up a bit). I've even considered the Nitro Ultimate. Any opinions amongst these boards? Any others I should seriously consider given my interests?
Also, Im 59 and 150 lbs. Ive been riding a 157. Seems like many people are converting to smaller boards. Im thinking this may be worth it given the improved maneuverability, but I dont want to give up the ease in powder or the speed of longer boards. For my style, should I stick with a 157ish board or go down to 153?
Thanks a lot everyone
Maybe a custom X - if you like to charge it might be a nice upgrade from your custom. Will you be riding out east or west?
Thanks Lamps-
I actually hadn't looked much into Custom vs Custom X so going to have to do that. Any reason why X is so much better, making the $100 price jump a rationale one?
I'm purchasing my new board with my focus on riding out West. If I ride out East, I may bring this new board along or even just ride the older one for the less than optimal snow.
I have no experience on either of these boards though looking at them in comparrison.
5 of 10 on feel rating. Middle of the road feel not to soft or stiff. soft enough to butter around and play a bit yet stiff enough to charge and bomb runs to an extent.
It's a directional twin camber board that uses light weight wood core. binding mounts are slightly set back to allow the nose to cut through pow and increase flotation and pop on the tail.
Custom X
7 of 10 on feel rating which gives you a slightly more stiff, responsive board that is more stable at higher speeds as well as better edge hold while carving hard.
The Custom X is loaded w/Burton tech. It's A directional twin camber board with a super light wood core "Dragon fly" core which is composed of 500 independent laminations, each individually oriented within the core, result in superior weight-savings, strength, and energized response. This board also features what they call "Multizone EGD" where they strategically input four separate zones, where the wood grain is perpendicular to the core adjacent to The Channel to improve board strength and edge hold. Additionally their "Squeezebox" tech is the use of soft pliable wood under your feet and a harder more ridged wood and the tip and tail for increased maneuverability and board pop. The boards tip and tail has been tapered in thickness to help reduce swing weight for the spin junkies and finally the board is Pre-broke in at factory so you don't have to do it.
So needless to say if it were me looking at these two boards I definitely say the Custom X is worth the extra $100 bones. That's just my opinion feel free to formulate your own. Burton's web site does a good job of explaining all the tech and the reasoning behind it just gotta do the research brotha! good luck, have fun and ride safe.
How does the Machete GT stand up when considering these other boards? Looks like it may also fit the profile of what I'm looking for
Alright, after some research into it all I'm left torn between some sweet boards. So...
Lib Tech TRS 154 or 157
Never Summer Cobra 155
Burton Custom X 156
That's it. What do you think would be the best choice?
However, for the vast majority of riders the Custom is a much better board. The X is just too stiff and too much board for most riding - most riders do not benefit from the extra charging ability of the X but will miss the playfulness and forgiveness of the standard Custom.
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credit card question please help
Quoting Amy127:
Yes but if you even have a small balance they will charge you interest on the entire balance for the introductory period.
Do u think ill have minimum payments? I need to get new upholstery for my sons wheelchair that's about 325$ I'm wondering about how much id have to pay min per month? some months I might be able to do more but I'm just living check to check so don't want to do it if I incure a lot of interest or can't make monthly minimum payments.
Quoting ambermario4ever:
Yes that is what it means but if you read the small print you have to have like perfect credit to get that deal.
yeah somwhow I have great credit but.dont use cards very often bc I am very low income and know that just bc I have X amount for a.credit.limit doesn't mean ill ever be able.to.pay back. I wonder how.they determine the minimum payments per month? I hate calling the number to ask.
Quoting thedathree:
Wel if you have had loans or other cards before and always paid them on time and or paid them off you would have good credit. My on the other hand ki have never had a loan or credit card so I do not have any credit at all and now that I am 25 I can't get a card because of it.
Sarah Luciano
(10-16-06) (11-27-08)
Typically your minimum payment is 2% of the balance on your card. So, if you had a $1000 balance you'd pay $20/month.
Credit Repair = http://www.ftc.gov/bcp/edu/pubs/consumer/credit/cre13.shtm
A secured credit card = http://money.msn.com/credit-rating/9-fast-fixes-for-your-credit-scores-weston.aspx
HOW to get a secure CRCD = http://www.bankrate.com/finance/credit-cards/10-questions-before-getting-a-secured-credit-card-1.aspx
Repair Credit = http://www.myfico.com/crediteducation/improveyourscore.aspx


text:
Financial Aid With Ged
ऀð ऀð ऀð ऀð ऀð ऀð ऀð ऀð GED SCHOLARSHIP APPLICATION ऀð In order for students to be eligible for any Institutional Scholarship, they must complete the Free Application for Federal Student Aid (FAFSA) annually and eligibility for federal aid confirmed. … Fetch This Document
FINANCIAL AID OFFICE 3250 St. Matthews Road ∙ Orangeburg, SC 29118 ∙ (803) 535-1224 phone High School Diploma or GED Will you have received your high school diploma or GED prior to the 2011 fall semester? … Retrieve Doc
Gloria – YouTube
It's difficult because of my immigration status and financial aid. But even if you are undocumented, go to any adult learning center and make your GED is priority" … View Video
Major Breakthrough For Homeschoolers Seeking College …
August 24, 2007 Federal Requirements for Homeschoolers Seeking College Admission and Financial Aid Colleges and universities frequently ask two questions about homeschoolers: (1) Are homeschoolers eligible for financial aid without obtaining a GED or passing an ability-to-benefit test? … Fetch This Document
VALID HIGH SCHOOL DIPLOMA OR GED REQUIRED TO RECEIVE FINANCIAL AID In order to receive financial aid students must have a valid high school diploma or GED. … Read Here
CSKT Education Dept. Scholarship Deadline Looms Close, Apply Now
PABLO — Whether the economy is up or down, it's a typical decision for tribal members of all ages to make a decision to enter college; and knowing what to do can make a world of difference between making it work or dropping out. … Read News
Students Without A High School Diploma Or GED – Can I Qualify …
4/11. Students without a high school diploma or GED. Can I qualify for financial aid if I haven't completed my high school diploma or GED? Yes it is possible, although additional testing criteria exists for students who have not completed their high school diploma or GED. … Read More
Financial Aid Ability-to-Benefit Verification Form
Financial Aid /June 28, 2011 . Financial Aid . Ability-to-Benefit Verification Form • Has the recognized equivalent of a high school diploma, such as a GED • Has completed homeschooling at the secondary level … Retrieve Full Source
Government Aid And Money – No Grants Needed
Government Aid and Money – No Grants Needed Part 1: Most help to individuals does not require a grant. By Robert Longley, About.com Guide … Read Article
Garnet Career Center, Charleston, WV – YouTube
Academic Advising, Accounting Data Processing, Adult Basic Education Classes and Ged Testing Cent, Adult Basic Education Classes and Ged Testing Center, Business Education, Certificates, Certified Nursing Assistant, Evening and Day Classes Available for Some Classes, Financial Aid … View Video
Board Of Regents Visits Kansas State University
The Kansas Board of Regents made a special stop in Manhattan on Thursday and Friday, visiting Kansas State University and learning about all of the different happenings on campus. … Read News
General Educational Development – Wikipedia, The Free …
General Educational Development (or GED) tests are a group of five subject tests which, when passed, certify that the taker has American or Canadian high school Those courses eat up precious college financial aid resources but generate no college transcript credits. … Read Article
Financial Aid For GED Recipients
Adult Education — Affordability Financial Aid for GED Recipients Financial Aid for GED Recipients … Document Viewer
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text:
Pudding Face Activity
When your child makes cute and delicious pudding cup faces, he has also created edible works of art!
What You Need:
- Vanilla, chocolate, or butterscotch pudding mix or pre-made pudding cups
- Candy decorations (not all of these are needed, just enough to create faces on pudding surfaces) such as: licorice pieces, raisins, chocolate chips, butterscotch chips, coconut shavings, jelly beans, lifesavers, M&M's, gum drops, gummy worms, red dots, and sprinkles
- Bowls or small clear plastic cups
- Spoon and butter knife
What You Do:
- Tell your child he will use candy to create faces on pudding cups, and he'll get to eat the whole thing!
- Your child can help you make pudding from a box of pudding mix (following package directions), or you can provide pudding already pre-made from purchasable pudding cups.
- Have your child use a spoon to scoop pudding from the homemade batch or from pre-made cups into a larger bowl or clear plastic cup. After the child has filled the bowl, the parent can use a knife to smooth out the surface of the pudding.
- Let your child pick out the candy decorations that he would like to use to create a pudding "face" on the surface of the pudding. He may want to use a red licorice piece, a gummy worm, or a red life saver for a mouth; M&M's, red dots, lifesavers or chocolate chips for eyes; and perhaps coconut shavings or gummy worms for hair. These are just suggestions; the final design is entirely up to your child!
- You may wish to photograph the finished pudding face creation before your child eats it, as it's sure to be a one-of-a-kind face!
- He may want to create more than one pudding face, for example as desserts for your whole family.
Let him eat and enjoy his pudding face creation!
Beth Levin has an M.A. in Curriculum and Education from Columbia University Teachers College. She has written educational activities for Macmillan/McGraw-Hill and Renaissance Learning publishers. She has a substitute teaching credential for grades K-12 in Oregon, where she lives with her husband and two daughters.


text:
Isla Vista fire warnings go out
Last week of school pranks could lead to jail time
ISLA VISTA, Calif. - Warnings have gone out in Isla Vista about the consequences of intentionally set fires, especially for residents who burn furniture as they leave for the summer.
Santa Barbara County Fire Captain David Sadecki says students can face serious penalties including jail time, fines and even find themselves listed as a "registered arsonist," depending on their offense.
"If you do light a fire and we catch you you will be held liable for it," said Sadecki. The District Attorney's office has a special arson team to handle these cases.
Many residents, who are mainly UC Santa Barbara students say they see couch fires throughout the year, but they increase as students move out. One resident saw three on his street recently. Damage can be seen on the asphalt where furniture burned.
"I think it could definitely be dangerous,"said resident Henry Jones. "And I think with the fumes it releases it could be pretty toxic. Kids jump over it and stuff and think it's funny. It could turn bad real fast I think."
Some residents know who may be responsible but, "if anyone asks, it's the guy next door. It's not you, "said Hank Dorsey.
Sadecki says calls for what are sometimes referred to as "nuisance" fires, "takes us away from the job we need to do. It takes us away from other calls for help."
How often does it happen? Student Crystal Powell said, "just park out here on the weekend and you will see it."


text:
Ever wondered how kids meals compare nutritionally between McDonalds, Burger King and KFC. I have. Here's what I found…
Introductory Comment
This little experiment isn't intended to show any one brand up, rather it was to satisfy my own curiosity. It's worth noting that there are hundreds of combinations available which I haven't compared, instead choosing a small selection of popular combinations that I would likely choose. There are other combinations that will be more healthy and unhealthy than those I have shown. All fries are unsalted.
Happy Meal including Chicken Nuggets, Fries and Fruit Shoot
Calories 420
Fat 21g
Salt 1.2g
Comment: A pleasant surprise really, the calorific value is reasonable (around a quarter of a child's daily allowance). The amount of salt in this meal was the second highest out of the 6 combos.
Happy Meal including Hamburger, Fries and Coke
Calories 590
Fat 20g
Salt 1.8g
Comment: Calorific value much higher here, mainly due to the coke. Salt was by far the highest of all selections.
Kids Meal including Fillet Burger, Fries, Fruit Shoot & Yoghurt
Calories 587
Fat 20.8g
Salt 0.8g
Comment: The second highest for calories, but quite a low salt value. Includes desert which other combos do not.
Kids Meal including Chicken Strips, Corn, Fruit Shoot & Yoghurt
Calories 479
Fat 23.2g
Salt 0.9g
Comment: Calorific value is relatively low but this meal has the seond highest fat content. Lower in salt than other combos. Includes desert which other combos do not.
Burger King
Kids Meal including Hamburger, Fries and Diet Coke
Calories 520
Fat 25g
Salt 0.8g
Comment: Very high fat content and calorific value over 500. Salt is relatively low
Kids Meal including Chicken Tenders, Fries and Coke
Calories 510
Fat 23g
Salt 0.97g
Comment: Middle of the road in calories but quite high in fat.
Burger King does badly for fat content. McDonalds performs poorly for salt and choose the wrong combo from KFC and consume nearly 600 calories. My favourite combination was the KFC chicken, corn, fruit shoot and yoghurt meal. Its quite high in fat but includes a vegetable, protein and dairy for maximum variety and it has the yoghurt providing a desert. I was surprised how evenly each brand performed overall. The biggest alarm bells rang when I saw how much full sugar carbonated drink added to the values.
What do you think?
McDonalds photo by flickr user noodlepie
KFC photo by flickr user viZZZual.com
Burger King photo by flickr user paranoias80


text:
Author Affiliations: Division of Genetics (Dr Neilan and Mss Donovan, Kim, and Jou) and Departments of Laboratory Medicine (Dr Wu) and Neurology (Dr Kang), Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts; and Department of Neurology, Texas Scottish Rite Hospital for Children and University of Texas Southwestern Medical Center, Dallas (Dr Delgado).
Gait difficulties, tremors, and coordination difficulties are common features of Cockayne syndrome that are consequences of leukodystrophy, cerebellar atrophy, and demyelinating neuropathy, but no pharmacotherapy for these disabling symptoms is available.
To determine whether carbidopa-levodopa relieves tremors and other motor complications of Cockayne syndrome.
Mutation analysis and case report study.
Hospital clinic and genetics research laboratory.
We studied 3 patients with Cockayne syndrome, a rare autosomal recessive neurodegenerative disorder for which no known treatments are available.
Carbidopa-levodopa therapy.
Main Outcome Measures
Status of tremors, ability to perform daily tasks, serial physical examinations, and results of handwriting samples.
All 3 patients had a clear reduction in tremors and improvements in handwriting and manipulation of utensils and cups.
Patients with Cockayne syndrome should be evaluated carefully for movement disorders. A clinical trial should be considered to evaluate this therapy further.
Cockayne syndrome (CS) is a rare autosomal recessive neurodegenerative disorder caused by mutations in ERCC8 (CSA or CKN1)1 and ERCC6 (CSB).2 The clinical phenotype of CS is distinctive and includes microcephaly, intellectual disability, short stature, cutaneous photosensitivity, pigmentary retinopathy, cachexia, premature aging, and deafness.3,4
The pathophysiologic features involve a defect in nucleotide excision repair (NER), a process that reverses a range of DNA helix-distorting lesions, including damage caused by UV radiation.5 Cockayne syndrome is classified as an NER disorder, along with xeroderma pigmentosum, which is characterized by severe cutaneous photosensitivity and a high risk of skin cancer, and trichothiodystrophy, which is associated with photosensitivity, poor growth, neurodegeneration, and brittle hair.6
Gait difficulties, tremors, and coordination difficulties are common features of CS that are consequences of leukodystrophy, cerebellar atrophy, and demyelinating neuropathy, but no pharmacotherapy for these disabling symptoms is available. Among patients enrolled in a genetic study of CS, we studied 3 adolescents with a relatively mild course who had clear tremors and motor difficulties.
The setting was a hospital clinic and genetics research laboratory. Patients and their parents were enrolled in a research study of the genetics of CS following an approved protocol of the Children's Hospital Boston, and informed written consent was obtained. Mutation analysis of the ERCC8 (CSA) and ERCC6 (CSB) genes was performed by direct DNA sequencing of the coding exons and their flanking splice junctions on a DNA analyzer (ABI Prism DNA Analyzer; Applied Biosystems, Foster City, California). Control DNA samples were obtained anonymously from 96 patients unaffected by CS. Three patients with CS identified through this genetic study were given therapeutic trials of carbidopa-levodopa on a clinical basis.
A 13-year-old, right-handed girl with CS had increased muscle tone in the lower extremities (left greater than right) since the age of 15 months. Her parents first observed bilateral hand tremors at 3 or 4 years of age. She has an unsteady gait and difficulty with motor tasks, including writing, holding beverages, buttoning, zipping, and putting on socks and shoes. She uses training wheels on her bicycle.
Physical examination findings revealed bilateral heel cord contractures, jerky ocular pursuits, and dysmetric saccades. Fluctuating dystonia was present in both legs, with mild distal weakness. Tendon stretch reflexes were diminished in the arms and at the patellae and absent at the ankles, with flexor plantar responses. Vibration sensation was diminished. Bilateral intention tremors were present, with dysmetria and dysdiadochokinesia, but she had neither a postural or resting tremor. She navigated stairs with mild difficulty and some bradykinesia. Further clinical details are given in Table 1. Motor nerve conduction studies of the right tibial nerve recording abductor hallucis brevis demonstrated slowing of nerve conduction, with a latency of 6.7 milliseconds (reference range, <5.7 milliseconds), an amplitude of 5.9 mV with ankle stimulation and 3.1 mV with popliteal stimulation (reference range, >2.8 mV), and a velocity of 26 m/s (reference range, >41 m/s). F-response latency was 40 milliseconds (reference range, <56 milliseconds). Bilateral sural sensory responses were absent.
Mutation analysis demonstrated inheritance of 2 compound heterozygous CSA mutations by this patient: c.37G>T (p.E13X), a nonsense mutation inherited from the father that was previously reported in an unrelated patient with CS7; and IVS11-1G>C, a novel splice acceptor mutation inherited from the mother that alters the invariant AG dinucleotide (Figure 1A and B). Neither mutation was present in the control samples. The results of genetic testing for GCH1 were negative, excluding the classic form of dopa-responsive dystonia.
DNA sequence chromatograms: CSA gene sequencing demonstrates compound heterozygous mutations in patients 1 (A and B) and 2 (C and D); CSB gene sequencing demonstrates a heterozygous mutation in patient 3 (E). Arrowheads indicate locations of the mutations.
A combination of carbidopa, 25 mg, and levodopa, 100 mg, was prescribed at initially a half tablet by mouth twice a day and then increased to 1 tablet twice a day. Approximately 1 week after starting the full dose, she and her parents noticed a reduction in her tremors, improvement in her handwriting, and better manipulation of utensils. Eight weeks after the initial visit, her handwriting sample showed marked improvement (Figure 2A and B), her hypertonia had improved, and her dysmetria had diminished, with a significant beneficial effect on her schoolwork.
Handwriting samples from the study patients: sample from patient 1 when not receiving (A) and receiving (B) carbidopa-levodopa; and sample from patient 3 when not receiving (C) and receiving (D) carbidopa-levodopa. Note the large, irregularly formed letters when the patient was not taking medication (A and C) and the smaller, firmer writing, with straighter lines and rounder curves, when the patient was taking medication (B and D). Each panel was scanned from an 8½ × 11-in sheet of paper.
A 14-year-old boy with CS had significant tremors that limited his activities of daily living. He had poor feeding through the first year of life. Acquired microcephaly was observed at the age of 14 months. He was diagnosed clinically as having CS at the age of 5 years. He began riding a bicycle at 5 years. Chronic complications of CS observed include tremors, hypertonia, decreased lacrimation, and cutaneous photosensitivity.
Physical examination findings revealed hypertonia and hyperreflexia, head titubations, severe resting and intention tremors, dysmetria, dysdiadochokinesia, and a wide-based ataxic gait. Further clinical details are given in Table 1. Neuroimages are presented in Figure 3.
Cranial computed tomographic scans, taken at the ages of 9 years (A) and 15 years (B); the scans demonstrate bilateral basal ganglia mineralization and diffuse brain atrophy. The basal ganglia mineralization remains stable during this interval, whereas the ex vacuo ventricular dilation becomes more prominent over time.
Mutation analysis demonstrated 2 compound heterozygous CSA point mutations: c.479C>T (p.A160V), a missense mutation inherited from the mother that was previously reported in another patient8; and c.1052G>A (p.S351N), a novel missense mutation inherited from the father (Figure 1C and D). Neither mutation was found in the control samples.
His tremors caused significant difficulty writing, feeding, and dressing. A trial of clonazepam did not result in an improvement in the tremors. He was prescribed a combination of carbidopa, 25 mg, and levodopa, 100 mg, and took half a tablet each morning, which improved his tremors; the resting tremor improved more than the intention tremor. The dose was gradually increased, and after 8 months he was taking 1 full tablet twice a day. His handwriting has improved, and he can color much more accurately than before. He has better endurance with activities such as walking, swimming, and riding a bicycle.
A 14-year-old girl with developmental delays was at her baseline until 2 years before presentation, when she developed motor difficulties. She was no longer able to climb a rope ladder or ride a pony. She developed gait difficulties, falls, tremors, choking and gagging on food, difficulty buttoning and zipping clothes, difficulty tying shoelaces, and problems navigating stairs. Her birth history was notable for the ultrasonographic finding of dilated cerebral ventricles and tube feedings in the first week of life.
Physical examination findings revealed a beaked nose and bilateral hand weakness. Tendon stretch reflexes were normal in the upper extremities, increased at the patellae, and absent at the ankles, with extensor plantar responses. She had fluctuating rigidity in the upper extremities, especially at the elbows, but without contractures. Dysmetria and dysdiadochokinesia were present. She had a mild coarse postural tremor bilaterally and a shuffling gait with bradykinesia. Further details are given in Table 1. Nerve conduction studies demonstrated a mild sensory polyneuropathy (Table 2), and the results of needle electromyography of the right leg were normal.
Mutation analysis demonstrated 1 novel heterozygous missense mutation in CSB, c.3806A>C (p.D1269A), which was inherited from the asymptomatic father but was not observed in any of the control samples (Figure 1E). As yet, no other mutation in CSB has been identified in this patient. No mutations in CSA have been identified, but CSB protein was deficient in cultured skin fibroblasts (E.G.N., unpublished data, October 27, 2006). The results of genetic testing for GCH1 mutations were negative.
Therapy with a combination of carbidopa, 25 mg, and levodopa, 100 mg, was initiated at a half tablet twice a day. Three months later, her tremor had resolved, she used utensils more adroitly, she dressed herself better than before, and her movements were smoother. Her hypertonia had improved, and her steps were less shuffling. At 6 months, she continued to have clear improvements in multiple motor tasks with a significant beneficial effect on her daily life. At the 6-month visit, thyroid studies demonstrated mild hypothyroidism and thyroid supplementation was initiated. Nerve conduction studies demonstrated a sensory neuropathy, possibly related to the thyroiditis. Vitamin B12 and vitamin E levels were normal. Cerebrospinal fluid neurotransmitter metabolite, 5-methyltetrahydrofolate, neopterin, and biopterin levels were essentially normal during a break from taking carbidopa-levodopa. Handwriting samples taken during and after this drug break illustrate the effect (Figure 2C and D).
We describe 3 adolescents with CS, all of whom had tremors and motor difficulties that responded to therapy with carbidopa-levodopa, with a significant beneficial effect on their daily activities and ability to care for themselves. These activities included tasks such as writing, dressing, and eating and drinking. The parents of all 3 patients reported worsening of tremors and increased difficulty with motor tasks when doses of carbidopa-levodopa were unintentionally missed. This simple intervention has the potential to improve the quality of life significantly in affected individuals.
Our findings raise intriguing questions regarding the pathogenesis and therapy of CS. Delayed-onset progressive movement disorders have been observed in the setting of static acquired brain lesions, such as perinatal injury, stroke, and head trauma.9 Further localization is suggested by a comparison of the neuropathologic features of CS with those of Parkinson disease. In Parkinson disease, degeneration of the substantia nigra occurs, which provides dopaminergic input to the putamen. Calcification of the putamen is a hallmark of CS,10 with lesser degrees of calcification in the caudate, globus pallidus, and thalamus.11 In addition, the expression of glutamate transporters appears to be altered in the globus pallidus.12 Neuropathologic studies generally suggest preservation of the substantia nigra; however, 1 report13 observed brown discoloration of the substantia nigra. These findings suggest that the dopaminergic pathway may be injured in CS. There is also 1 report14 of a patient with CS whose hyperkinetic movement disorder improved with deep brain stimulation of the ventral intermediate nucleus of the thalamus. Some of our patients' physical findings suggest the presence of cerebellar dysfunction, but the significance of this is unclear in light of the pathologic findings and their response to levodopa-carbidopa.
The link between the pathologic findings in the basal ganglia and the NER pathway is not yet clear. Recent work15 suggests that endogenous DNA damage may contribute to the pathophysiologic features of NER disorders. It is possible that the deep nuclei of the basal ganglia are more vulnerable to endogenous DNA damage and preferentially degenerate in CS, thus causing the movement disorders observed in our patients. Because this intervention in CS has not previously been described, further studies are warranted.
Correspondence: Peter B. Kang, MD, Department of Neurology, Fegan 11, Children's Hospital Boston, 300 Longwood Ave, Boston, MA 02115 (email@example.com).
Accepted for Publication: January 4, 2008.
Author Contributions:Study concept and design: Neilan, Wu, and Kang. Acquisition of data: Neilan, Delgado, Donovan, Kim, Jou, Wu, and Kang. Analysis and interpretation of data: Neilan, Delgado, Jou, Wu, and Kang. Drafting of the manuscript: Kang. Critical revision of the manuscript for important intellectual content: Neilan, Delgado, Donovan, Kim, Jou, Wu, and Kang. Obtained funding: Neilan. Administrative, technical, and material support: Neilan, Jou, and Wu. Study supervision: Kang.
Financial Disclosure: None reported.
Funding/Support: This study was supported by the National Organization for Rare Disorders, Mark and Katherine Pelson, the Luke O'Brien Foundation, and the Ben & Riley Sullivan Golf Outing (Dr Neilan); and by grant K08 NS48180 from the National Institute of Neurological Disorders and Stroke (Dr Kang).
Additional Contributions: We thank the families for participating in this project and providing the handwriting samples. Joseph J. Volpe, MD, and Basil T. Darras, MD, provided helpful comments on the manuscript, Julia Parzych, BA, and Ashley Catalano, BS, assisted with the figures, and Amy R. Danehy, MD, interpreted the neuroimaging studies.
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