text:
Hootan Dehbonei
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Think you're king of the road? Try to answer these questions administered by the California's Department of Motor Vehicles.
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text:
Differentiation blocks are hallmarks of leukemia
and represent the inability of these cells to
develop normally. Therefore, understanding how
blood normally differentiates is critical to
understanding leukemia. HoxA10 represses lineage-
specific genes in undifferentiated cells, and that
during differentiation HoxA10 was phosphorylated
within its homeodomain. These differentiation-state
specific phosphorylations reversed HoxA10 gene
repression and allowed for further differentiation.
The SHP2 phosphatase maintains the dephosphorylation
state of these residues in undifferentiating cells
and leukemia-associated SHP2 mutations increase
HoxA10 repression in both undifferentiated and
differentiated cells, leading to differentiation
block. Furthermore, HoxA10 phosphorylation state, as
regulated by SHP2, influences leukemia progression
and provides evidence of a two-hit model of
leukemogenesis in mouse experiments. This research
highlights how science can be used to understand the
fundamental molecular mechanisms involved in human
disease to develop treatments to improve the quality
of life for patients suffering from various cancers.
Stephan, Lindsey.
Stephan Lindsey received his PhD from Northwestern University and
has always been fascinated by science and how the world around
him operates. As an accomplished biomedical researcher, he is
currently examining the transcriptional events involved in normal
blood development as a means to understand how it goes awry
during leukemia progression.


text: What does it mean when a root springs from the ground? 9,035pages on this wiki Edit Classic editor History Talk0 When a root springs from the ground, it means that a fully grown Evil Tree is somewhere in that world - It can be far away or even next to you! Learn more about this onthe RuneScape Wiki.See Evil Tree. Retrieved from "http://runescape.answers.wikia.com/wiki/What_does_it_mean_when_a_root_springs_from_the_ground?oldid=90091" Categories: Answered questions Add category Cancel Save


text:
A couple of weeks away from the end of its Q2, Spreadtrum (UNKNOWN: SPRD.DL ) has become more optimistic about its performance for the quarter. The company on Wednesday updated revenue guidance for the period, predicting a top line of $270 million-$278 million.
This would represent a quarter-over-quarter increase of 42.9%-47.1%. It is also quite a boost from Spreadturm's previous guidance, which was $220 million-$228 million.
In the press release announcing the news, the firm quoted CEO Leo Li as saying the guidance increase is "due to the continuing strong demand throughout the quarter for low-cost smartphones. We are at the start of a multi-year cycle in China and emerging markets of subscribers transitioning from 2.5G feature phones to smartphones."
Spreadtrum's Q2 ends on June 30.


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A project of People For the American Way dedicated to monitoring and exposing the activities of the right-wing movement. Learn More >
Garlow Warns Religious Right Voters That Only Gingrich Can Defeat Romney
Yesterday, leading Religious Right activist and Gingrich-surrogate Jim Garlow appeared on The Steve Deace Show, where he joined former congressman J.C. Watts in praising Gingrich. Deace, who recently endorsed Gingrich, asked Garlow why evangelical voters should back Gingrich when many feel there are candidates who are more ideologically pure and do not have Gingrich's personal baggage. Garlow commented that Religious Right voters continue to be "defeated and frankly humiliated" by "hyper-spiritualizing" elections, when they should be backing candidates who have a chance at winning. He said Bachmann, Perry and Santorum do not stand a chance against "the Romney machine," and that Christians need to start using a "healthy, biblical, biblically-founded pragmatism" and that "the Holy Spirit can show us" in order to win political fights:
Garlow: The second component is that we do not as Christians assess the problem quickly enough with a healthy, biblical, biblically-founded pragmatism. For example, I see people hyper-spiritualizing this election, they say, 'well God parted the Red Sea,' well he did it once! But he told Noah to build a boat, in other words, get in there and float on this thing. So we're being out-fought, unfortunately, because we hyper-spiritualize way too much. Let me make it real, ground-tested and practical, and this will probably disturb some people. Michele Bachmann is wonderful but she has no cash and no traction; Rick Perry is wonderful, I think he's absolutely fabulous, I hope he has strong influence in the nation in the future along with Michele Bachmann, he has lots of cash but his articulation skills have harmed him seriously and he cannot overcome them, not now; Rick Santorum is wonderful but he has no cash and no machinery, if he wins Iowa he needs to be spending $3 million a week minimum to carry him through to try keep up with the Romney machine, so Romney's best interest is to land Rick Santorum right up there at the top. People are not thinking through a strategy and by lack of a biblically-founded pragmatism that the Holy Spirit can show us, the lack of a strategy, we are being defeated and frankly humiliated and our biblical rights are being robbed from us.
Last week, Garlow interviewed Gingrich on a conference call with Iowa pastors that also featured American Family Association founder Don Wildmon and "Restoration Project" organizer David Lane, both of whom previously supported Rick Perry but have since endorsed Gingrich. On the call, Wildmon warned conservatives against splitting their vote (2:45). Gingrich criticized abortion rights (8:15), marriage equality, which he called "a violation of the core framework of our civilization" (9:20), and the judiciary (10:50), warning that "the Obama, European secular socialism is fundamentally different and in a key way threatens our rights as citizens" by turning Americans into subjects of the state:
Filed Under
People:Newt Gingrich , Jim Garlow, Steve Deace, Don Wildmon , Donald Wildmon , David Lane
Topics:Election 2012
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The Dutchman Sno-Park area, located near Mt. Bachelor on the Cascade Lakes Scenic Byway, closed to snowmobiles this past weekend due to low snow levels, Deschutes National Forest officials said Monday.
Early snow melt necessitated the earlier than normal closure for the area. Under a Forest Order, the Deschutes National Forest must put the closure in place once snow levels are below 12 inches in depth. The closure will continue until adequate snow falls in the winter.
Traditionally, many snowmobilers enjoy access to the high country around Dutchman Sno-Park through Memorial Day weekend.
For more information, please contact Marv Lang, Trails Manager at 541-383-4793.


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More sports
Spectre '84 ties final game
The U-13 Spectre Girls ended their season with a 0-0 tie Dec. 14 when they played the Gig Harbor Fury, the number one team in the league. The Spectre defense, led by Megan Beden, Kelsey Hall, Lindsay Mercier, and Kristina Skogan were standouts.
Boat launch savings
Boaters, kayakers, and water sports enthusiasts can save 25 percent on launching fees, now until May. Call (360) 902-8500 for information.
Sports World moves to Towne Center
After 15 years in Woodinville, Sports World will move from Woodinville Plaza across the street to Towne Center. The updated and newly remodeled store will open Jan. 2, said owner Paul Zahajko. For information, call 483-6695.


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UNIVERSITY PARK - A smile.
For most of today's youth, it doesn't take much to get a grin out once in a while.
But for the participants in the 43rd Annual Special Olympics Summer Games at Penn State University, that can come to be a challenge. For three days on the Penn State campus however, smiles abound among the hundreds of kids having the time of their life.
Article Photos
Sentinel photo by TIM?SHUMAKER
Tracy Foy, a member of the Mifflin County Huskies Special Olympics basketball team, takes a shot during a state games contest Friday at Penn State.
Take any scholastic sporting event. You always see players frustrated and complaining to coaches or officials. Today's youth take a lot of things for granted. But that doesn't happen with the Special Olympics. This is their World Series - their Super Bowl. With heart, and a whole lot of energy, dreams do come true.
Mifflin County sent a group to Penn Sate this weekend to make their dreams to come true. Those dreams came true for the Mifflin County Huskies 3-on-3 basketball team.
Prior to the team's first game of the day Friday, echos were ringing throughout the Intramural building on the Penn State campus. Chants such as, "Take it to 'em" and "Never give up" signified the start of the Huskies' chance at gold.
On the team are four exuberant youths: Walter Snyder, David Fye, Tracy Foy and Bobby Fisher. Each team member has something different from the other to offer.
The Huskies made a nice turnaround after dropping their first game, 16-11, to Bethlehem Wolfpack II in the morning session, winning against The Hotshots 20-8 to split their first day of competition. Even after the action concluded in the loss you would never know the outcome - high fives and cheering continued from the Husky team.
"At the beginning of the game I was thinking," Fye said. "And then I just had fun and that's all that matters."
In the latter half of Mifflin County's basketball doubleheader, one might think they were watching the NBA finals. The Huskies lit up the scoreboard early and often in a 20-8 rout. With teamwork and the most heart that has possibly ever been on the hardwood, the Huskies arrived.
Coach Kenny Varner said it was the best game the Huskies had played to date.
"That second game was awesome," Snyder said after the win.
The "never give up" mentality took over on the Penn State campus for the locals. Foy, Fisher and Snyder each made key buckets in the win. Fye's defense was big and the Hotshots could not handle his intensity.
"That game was the bomb," Fisher added.
Despite the loss in the first game, Mifflin County certainly had its fair share of highlights. Snyder and Foy each buried threes at crucial moments in the game to help their team out. Fisher made his mark in the paint, controlling any rebound within his grasp. And Fye was the Husky hustler.
Foy's three gave the Huskies an brief lead early in the first moments of play.
"That made me really happy," she said. "I'm glad we were able to play like that."
Snyder's three certainly had the flair for the dramatic. As one of the shortest players on the court, Snyder launched his shot over the outstretched arm of the defender. The result: plus three for the Huskies. The sound of his teammates let everyone in the State College area know it was buried.
"I was very surprised when I hit that three," Snyder explained. "He was right in my face. But I wasn't going to let him get the best of me."
The big man inside for the Huskies, Fisher, controlled the rebounds for most of the game. With his excitement, the Huskies were able to keep the game close coming down to the wire.
But in the end, the opponents were a little too much for Mifflin County to handle. But it wasn't because they played with more heart or energy. In fact, it was because the opponents' shots were falling. With Varner at their side, they did never give up.
"We played pretty good on defense," Fisher said. "That was good. I totally had fun and I always hope we can get some baskets and rebounds."
Let's face it, in today's society winning is everything. Getting a trophy is everything. Maybe Mifflin County returns with some hardware. Maybe not. But in the end, they know they did their best and played with heart throughout the week.
The Huskies have two more games this morning as the 43rd Special Olympics state games wraps up today in University Park.


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Celebrity look-alikes and impersonators converged upon the Golden Nugget in downtown Las Vegas for Celebrity Impersonators Convention on Monday. The event, in its 12th year, drew attendees from around North America to compete in a talent showcase, red carpet and awards ceremony. It is scheduled to run through Wednesday.
PHOTOS: Haven't I seen you ...
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Saturday, October 01, 2016
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Provider Resources for CKD
Click on the links below to find patient education materials, clinical guidelines and tools, and Other Resources for CKD.
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text: I Want My First Kiss by jbz 5/11/2012 | 3:45 35 Posted in News Justin kissing a little fan at Philadelphia meet & greet – November 4th. Tags:fans Related Bieber News Justin Bieber Does Stanky Leg + Surprise a Lucky Fan on Ellen -VIDEO Justin Bieber puts on Private Performance for 9/11 loved ones and Make-A-Wish kids -VIDEO Fan frenzy over Justin Bieber in Sydney for Hillsong conference – VIDEO VIDEOS: Justin Bieber meeting fans in LA (June19) Comments daughterofLordRauhl 5/11/2012 | 3:48 Aww… that's so cute and sweet. And now I get the accomplishment of having the first comment… but sweet pic. Justin's such a good person. bieberfever 5/11/2012 | 3:57 AWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWWW you are so nice to so people this one of the many resons i love you justin. Theresa Smith 6/03/2013 | 12:06 The girl is my daughter and it's not Philadelphia on 11/5. It's Louisville KY on Nov 2 – it was her Birthday! Google has the wrong city listed. biebs 5/11/2012 | 4:20 I would want Justin to be my first kiss Baylee Bieber 5/11/2012 | 4:20 OMG you that is on of the main reasons I love you Justin you try to make time for every Blieber!!! Love you so much. Follow me on twitter @mrsbieber4050 please i have bin trying to get you to follow me since i was ten iv bin trying to get you to follow me for 8 years 2 weeks ago. Appreciate and love so much> emily 5/11/2012 | 4:36 i wish he "made time for every belieber", this girls mom just spent over $500 for this to happen. Money buys justin kisses. :/ Jbsnumber1fan 5/11/2012 | 5:05 Lol I wouldve held up a poster that said "I wanna lose my virginity" lol;) narmadha 5/11/2012 | 11:37 lol Jbsnumber1fan 6/11/2012 | 4:55 Selena Gomez 5/11/2012 | 5:06 aww so sweet babe Amanda Marie 5/11/2012 | 5:26 That's so sweet. oxBelieberxo 5/11/2012 | 5:31 She was lucky to have a first kiss with Justin. #lucky JaylaBieber 5/11/2012 | 6:32 That sign is too cute! Swag 5/11/2012 | 6:42 Sooooooooo cuteeee:) Luv JB<3 iambieberpokemongirl1326 5/11/2012 | 7:01 awwww soooo cute Melissa bieber 5/11/2012 | 7:24 Oh how cute is that I wish Justin was my first kiss. I love u Justin. <3 Jsha bieber 5/11/2012 | 7:25 So lucky. mrs.swaggiebieber 5/11/2012 | 7:47 Adorable. Hes such a great person . Sigh … I never had a first kiss . anyway that's cute. That girl is so lucky.. # lucky narmadha 5/11/2012 | 11:42 never say never desy bieber 6/11/2012 | 12:29 YOUR SO RIGHT amber simpson 5/11/2012 | 7:58 hey justin bieber this is Kristen Amber Simpson you are so lucky justin tht is so cute and justin bieber may i have first kiss from u i would love u if u could come here and would ucall me &txt me u are my frist kiss here is my cellphone number is 8645389532 Andrea 5/11/2012 | 8:39 i want my FIRST KISS TOO jessie 5/11/2012 | 10:01 aww…. Liz Bieber 6/11/2012 | 2:30 i want to say that ,that girl is soooooo lucky to have a first kiss from justin i wish i had a first kiss from him ,love to JB 4 ever ,lyza BIEBER'S SHAWTY 6/11/2012 | 2:43 nice .. soooooooooo cute.. if i had da kiss i wouldn't wash my cheek.. lol.. 😀 JammyBelieve 6/11/2012 | 6:05 that girl is lucky.. essie j 6/11/2012 | 6:34 that's so adorable 😀 Real sastika belieber 6/11/2012 | 7:20 I wanna get that too!!! happy for the little lady!~ oww!! justin u're the best of ol!! I LOVE U u're so kind n selfless love u!!! belieber forever 6/11/2012 | 7:28 hey justin i also want that kiss uhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh i want it to plz give me plz i love u justin my babe Original justin bieber 6/11/2012 | 8:09 I want to kiss a lot fans beliebers lol ;):p:D:) Original justin bieber 6/11/2012 | 8:10 Answers questions:) desy bieber 6/11/2012 | 12:28 omg that is so cute she is so lucky thats y i love bieber because he is one nice person!! < Katelyne Belieber 6/11/2012 | 2:41 Awwwwwwwww so cute and that is why i love justin, he is so selfless iyana luvs justin bieber 6/11/2012 | 8:42 Cool sign! destineybieber 10/02/2013 | 10:43 THAT IS THE CUTEST THING EVAAA!!!!!!!!!!!!!!!!I LOVE U JB


text:
Peerless Universal Tilt SmartMount for 23-46" BlackItem#: P89-4288 | Model#: ST640 |
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Peerless Universal Tilt SmartMount for 22-46" Blac Product Details
Peerless Universal Tilt SmartMount for 23-46" Black
The SmartMount for 23" to 46" flat panel screens provides a versatile and secure solution for professional environments such as boardrooms, hotels and stadiums. This mount offers smooth, continuous one touch tilt, allowing for easy adjustment to achieve the perfect viewing angle without tools. The mount includes simple to align universal brackets and a unique wall plate that can be mounted to a single wood stud or concrete. For easy installation the mount is preassembled and includes a Sorted-For-You fastener pack with all screen hardware and security fasteners.
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text:
Last night's loss to the Phillies was a tough one to handle, probably the toughest of the season, and Mets bloggers are speaking their minds.
Anger/rage seems to be a current theme:
ToastyJoe reacts in kind:
Heck, I'm not even mad. That's amazing!Hotfootblog replies in a very similar manner:
I'm not even angry, I'm just stunned. You couldn't make this stuff up.
If anything good comes of this, then at least people will appreciate Billy Wagner more. That's the opinion expressed by The 'Ropolitans:
Closing, in my opinion, is one of the hardest jobs to do in all of baseball. We all know how nervous we (the fans) get when Wagner is on the mound with the lead, can you imagine how he feels??Mets Geek takes the calm and sensible approach to the "Why pull Johan Santana" commentary:
Everybody complaining that Johan Santana should have completed the game needs to relax. While I personally would have liked him to start the ninth inning with a short leash, if your bullpen can't get three outs with a three run lead then you don't deserve to be a first place team. Period.Faith and Fear in Flushing offers a list of things to remember as the season goes on.
Tonight's 7:10 match-up pins the Mets' John Maine (8-7) up against the Phillies' Brett Myers (3-9).
Will the Mets bounce back tonight?


text:
Process Development Jobs Still the Most...
Wall Street Decline Takes Its Toll...
Adapting to Evolving Business Environments Is...
Nothing Beats Immunoassays for Sensitivity, Specificity,...
Measuring the kinetic properties of biomolecules has become increasingly important in drug discovery and biomanufacturing. In areas such as immunization monitoring, clonal selection, and expression analysis, biosensors offer a clear advantage. In the past, it has been necessary to obtain purified or highly diluted molecules for such studies since crude samples have posed challenges for nonspecific binding, referencing, and system microfluidics.
The ability to analyze crude samples directly saves time, labor, and money. In this article, we show how the Attana 200 system (Figure 1) can be used directly with crude samples for off-rate screening of antibodies in hybridoma supernatants containing serum as well as for scaffold proteins in crude E. coli lysates.
Attana's biosensors are based on the quartz crystal microbalance (QCM) technology. By applying an alternating potential to a piezoelectric quartz crystal, the crystal can be controlled to oscillate at its resonance frequency. A change in mass on the crystal surface results in a proportional change in resonance frequency.
This means that when a ligand is initially immobilized on the crystal surface, the added mass can be measured in real-time without the need for labeling. The analyte is then injected, and binding of the analyte to the surface-bound ligand increases the mass further, whereupon a new shift in the resonance frequency is registered. Flowing buffer through the sensor chamber enables detection of the release of bound analyte.
Using different surface coatings provides the option of capturing or immobilizing molecules and, accordingly, QCM can be used to study molecular interactions in real time. The QCM technology enables not only the study of biomolecules of varying species such as proteins, nucleic acids, and carbohydrates, but also of vastly different sizes, ranging from peptides to cells.
Researchers often need to select clones for expression of a biomolecule either secreted from or accumulated inside cells. Hybridoma and phage display are the two predominant techniques used to create a repertoire of clones (Figure 2).
The Attana 200 system can be used through the entire hybridoma screening process. It offers a better methodology than ELISA for monitoring immunization, detecting the earliest antibodies of weak affinity. It also offers a powerful tool for screening of important properties such as off-rate constants early in the process, cutting sample numbers, and saving time. In addition, it is also widely used for establishing titers, due to its low coefficient variation.
In downstream processes such as characterization it can be used to establish specificity, kinetics, active concentration, cross reactivity, and for performing epitope mapping. Similarly, the Attana 200 system is used in the phage-display process to check specificity and correct folding of proteins in E. coli lysates after panning.
After re-cloning into the most favorable expression system, the Attana 200 system can be used under biologically appropriate conditions such as physiological temperatures to ensure that more relevant clones are chosen for expansion early in the process.
Alexander Kovacs, Ph.D. ([email protected]
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While Zika continues to garner a lot of news coverage, a Mayo Clinic survey reveals that Americans believe the country's most significant healthcare challenge is cancer. Compared to other diseases, does the possibility of developing cancer worry you the most?
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Therapy and medication is one way. You might want to give our method a shot… Check it out!
My chest closes up and no matter how hard I inhale oxygen doesn't seem to quite get to my lungs. Sweat pours down my face and puddles in the creases of my skin. One moment I am fine and the next it is as if I am dying. In my head I change that I am fine, I try to convince myself that it's just my body. My nerves are acting up and if I just manage to focus I'll be alright. I've gone through this dozens of times before and every one of them feels like it'll be the last. It's happening again, I'm having an attack.
Since I've been suffering from them I have learned one absolute truth: as with any other bodily ailment one treatment for attacks may not work as well for me as it does for the lady down the road. This is particularly true for these specific issues. Panic itself is an extremely personal thing. While you may be terrified of this is particularly true here because panic itself is such a personal thing. If I see a spider running at my foot I might flip out. You, on the other hand, may just step on it. It depends on who you are and what gets you worked up and these attacks are exactly the same.
That is why I am so confident with the Panic Away Program. It has a set up where you can find a way to fight off fear that works for you. It is treatment designed for people of all different background to use and so no matter what it is that set you off, calms you down, or how much time you have in the day to spend devoted to the program, you can find relief. If you've found that the usual methods of therapy and medication haven't work for you then I would highly, highly recommend you give this a go. It hasn't failed me yet and I've been free of episodes for so long I'm almost afraid to believe. This program really works and it can work for you too.
We wish you all the best and a profound cure
Eric, from the Successful Self Improvement Team
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I got a new Palm Zire just this week, so I don't know much about it
yet. I want to edit articles larger than the 4 Kb memopad allow. And I
want to write/edit them on both the Palm and the PC (windows).
I have downloaded OnboardC suite, and here is an editor that use a
format called DOC. So, if I could get an editor for windows that could
save in that format, it would be just perfect. Any suggestions? Are
there any good freeware editors? I don't mind pay 20$ to get a good
and stable editor, but If I can get something for free, that's
ofcourse better.
Also, I have read in the the help file to Palm Desktop that:
"With Palm® Desktop software, you can install other applications
individually and add new functionality to the Palm Desktop software.
For example, you might install an application that lets you record and
track your expenses for various trips. Buttons for any application
installed on Palm Desktop software appear on the Launch bar."
Where can I find such applications? Can I add a DOC editor that way?


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Post Office - Mesilla Park - Mesilla Park, NM - Phone: (505) 523-7088
Post offices are organizations which are involved with the postal system of a certain area. The mail services include posting of mail, receipt of mails, sorting mails on the basis of addresses, handling and transferring mails, and finally delivery of these mails to the intended recipients.
Post offices in Mesilla Park are not only involved in the mail related services but also offer non-postal services. The non-postal services which are obtained from the post offices in Mesilla Park include submitting government forms, passport applications, banking services and money orders. Post offices in Mesilla Park are responsible for delivering important mails to different locations, after proper sorting is done.
Alliance for Green Heat and NYSERDA Announce Seven Finalists in International Pellet Stove Competition
Two New York teams are among the finalists (Long Island, NY) Alliance for Green Heat and the New York State Energy Research and Development Authority (NYSERDA) today announced that seven pellet stoves have been chosen as finalists in the Pellet Stove Design Challenge. This international competition, administered by the Alliance for Green Heat, identifies innovative low emissions and high efficiency..


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Lauderdale County voters on Tuesday overwhelmingly approved renewing a property tax for schools for another 30 years, the TimesDaily in Florence reports.
The tax raises millions of dollars each year for county and Florence city schools, the newspaper reports. About 77 percent of voters approved of the renewal in Tuesday's vote.


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During the months leading up to this event, models were beckoned from everywhere to compete for a chance to be in the first Best Girls Calendar.Read More »
Kiteboarding in Merry Old England
The atmosphere here creates a rather different kiting experience. With a large steel works located a mile down the road, those on the hunt for a tropical session need not apply.Read More »
Kiteboarding (and overall sailing) Speed Record Ratified
The WSSRC has today ratified the last and final record from Luderitz, handing over the crown of Speedsailing to US Rob Douglas.Read More »
How to Keep Your Beach Open
Success stories about keeping beaches open for kiteboarding.Read More »
Alaska Road Trippin'
Way up north in Alaska, there's a little town where the wind blows across vast glaciers and up mountains so large that simply calling them big doesn't do them justice.Read More »
How to Sell Your Gear
Now that much of the new 2011 kiteboarding gear is on the market, it's time to think about upgrading your old busted gear to something new and shiny.Read More »
VIDEO: Mulcoy's World Episode 5
Follow Josh Mulcoy Kitesurfing,Surfing and Wakesurfing at home and around the world.Read More »
PKRA New Caledonia Final Results/Report
Andy Yates and Gisela Pulido take the world title in New Caledonia. All riders were on top of their game and did not take one minute for granted out on the water.Read More »
VIDEO: Mallory de la Villemarque: Welcome to My Pool!
Even trying to build a kite spot like that you could not make it that good!!!Read More »
VIDEO: Ruben Lenten in PAINKILLER
Watch wild man Ruben Lenten throw kiteloops like no one else.Read More »
The Kiteboarder Magazine December 2010 Issue Now Available Online
Read the entire December 2010 issue of The Kiteboarder Magazine for free online.Read More »
December 2010
*TRAVEL: Alaska Roadtrippin: A Trip to Thompson Pass *BACKWOODS: Tobago Cays with the Zenith Ocean Crew *How to Save Access at Your Local BeachRead More »
VIDEO: CAUTION CREW: Sander
This video was shot over the course of two afternoons at Waddell during the fall.Read More »
VIDEO: Bertrand Fleury in Indonesia
Wainman Hawaii rider Bertrand Fleury in his backgarden: Indonesia.Read More »
Nobile 2011 NHP Analyze This Board Review
The first thing our testers noticed was how easily driven the NHP is. It takes little power to get going and shoots upwind almost effortlessly.Read More »


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what are U up to today?
Today, I'm reading through the newest copy of Art Doll quarterly, drawing on moleskine notebooks for my etsy, oogling some new lace I got in the mail yesterday, and still rolling around inside the pages of Mixed and Stitched.
This week I'd like to share a quick & easy little garden project:
washtub herb garden
On Mother's Day I decided to plant some grape tomatoes and an herb garden in an old two-sided washtub I found at a local antique store. This is what is looks like 2 weeks later after buckets of rain, and lots of pep talks. I've already started to nibble on the arugula, but I'm really excited about the tomatoes. I left my washtub battered and rusty, but you could easily buy some outdoor furniture paint and spruce it up even more. {how fabulous would it look like with polka dots or flowers or birds painted all over it!} I've gone and planted herbs in mine, but I think it would make a fabulous strawberry grower or a beautiful deck flower planter too! Your imagination, and the garden center are your only limitations. Here's how easy it is:
- double-sided washtub or something similar
- 2 large bags potting soil
- 8 - 12 herbs / plants / flowers
- lots of sun & water
step 1:
If your washtub/container doesn't have a drain in the bottom you want to create one in each side so you don't drown your plants. You can either use a drill to make them or simply a hammer & nail to make about 5 holes in the middle of each side if it slopes or randomly around the bottom if your washtub has a flat bottom. Next, buy two big bags of potting soil, and pour one in each side of your washtub. If you only have one big basin you just need to put both bags in. If you want to cut down on cost you could fill the bottom half with fill dirt and rocks, but then you're looking at needing to fertilize. If you buy potting soil, that's usually mixed in and you can just plant and grow.
step 2:
Dig a softball size hole for each herb you want to plant. You want to give each plant enough room to grow so don't crowd them all together. The plant spike should tell you how far it needs to be from another plant, but I find about 4 to 6 inches is good. I like to use garden gloves so my fingernails don't get all grimy, but they are certainly not necessary if you don't already have a pair. You could use a trowel if you like too, but I find it easier to just dig them with my own two hands. The idea here is to keep cost down as much as possible, but still keep it capable of producing a nice harvest.
step 3:
I only did herbs in half because I wanted to try growing grape tomatoes to snack on in the other side. Last year I grew one to make sure they were tasty, and this year I have 4 going in the right half of my washtub garden. Just turn your plant upside down, and give it a little shake or wiggle to free it from the plastic container they come in. You want to break off about 1/4 of the rootball from the bottom to encourage growth, and then drop them into the holes you made in the soil. Push the soil in around your plant, and gently push down all the way around the stem making sure it's packed lightly so your plant won't fall over. You don't want to pack it in firm though or you risk injuring your plant.
step 4:
Continue on till both sides of your planter are filled and planted. In this side I planted:
top row - garlic & cilantro (not in the planter yet for this pic)
middle row - horseradish & basil
bottom row - arugula (yuhummy!)
The garlic and horseradish won't be ready until fall, but I love them both so they're worth the wait. Make sure you keep the plant info spikes that came with your herbs so you know what kind of care they need, and when you can harvest them. Most herbs need full sun to thrive so don't worry about needing a shady spot ... you can stick them right out in the sunniest spots, just remember to water regularly!
step 5:
After you've planted everything, you need to give it a BIG drink of water. The potting soil comes a little moist, but it dries out really quick in the sun so don't forget this step! Now all you have to do is sit back and watch your herb garden grow. As you can see from my rainy picture up top, it doesn't take very long for it to flourish. After two weeks of on and off rain, mine is growing like gangbusters! Don't forget to go out and talk to them too ... everybody needs a little encouragement to grow :)
So, that's it ... lickety split! Took me about a 1/2 hour from start to finish and cost under $50 including the planter, soil, and plants. I would love to see what you do with this How-To so please post links to your planters so we can take a peek!
{or plant somethin'}


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| ACADEMICS | Schools & Departments | World Languages | World Languages Applied Learning
Hands-on learning is an essential element of our world languages program. We encourage you to get involved in exciting interactive departmental activities that will complement skills you'll learn in the classroom. Opportunities include:
CONTACT USWorld LanguagesSullivan Academic CenterSuite S-303 and S-304508-929-8154


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Top Definition
Awesome, cool, sexy, hott, etc.
Damn, that girl with bleach blonde hair in da mall was swankyspanky.
ayon kay Kathara ika-29 ng Disyembre, 2007
Trending Now
Can you define these popular missing words?
to be cool, to look wonderful, the most rightious person there
the woman at the party was looking swanky spanky in that mini dress
ayon kay Kathara ika-10 ng Hulyo, 2008


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item(s) in cart
My Account X
Hatsan Escort Magnum Shotgun
Item # UF101086958
Key Features
Action - Semi-Auto
Gauge - 12 Ga.
Chamber - 2-3/4" & 3"
Barrel Length - 27-1/2"
Weight - 7.2 Lbs.
Our Price $299.99
Availability: Sold Out
- To buy online and deliver to a Gander Mountain store or an Independent Firearms Dealer, simply add this item to your cart. Click here for additional details.
- You must be at least 18 years old to purchase this item. State and local laws may vary.
- Additional discounts do not apply.
Prices, promotions, styles and availability may vary by store and online.
- details & specs
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details & specsback to top
Product DescriptionFast-acting and affordable, Escort semi-automatic shotguns are the perfect choice for the hunter on a budget. Escort's patented Fast Loading System provides faster loading of shot shells into the magazine without changing the aiming position. The Smart Valve Piston automatically adjusts the exact and reliable gas pressure needed for a wide range of loads. Nickel-chromium-molybdenum steel barrels are standard on all Escorts and hard white chrome-plated bores and chambers provide maximum durability and corrosion resistance on top of being easier to clean. This shotgun features a metal bead sight and a manual tang safety with an integrated barrel selector and includes modified and cylinder screw-in choke tubes. Its wood, metal, and bore are all in good condition.


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Best route map between Corpus Christi, TX and Odessa, TX. This route take about 484 Miles.
The distance and estimated time is placed on the right depending on the status of the road.
, 15:52
* You can see Corpus Christi, TX and Odessa, TX photos above. We provide this photos from Google Panoramio service.
* Corpus Christi, TX weather as celsius: °C
* Odessa, TX weather as celsius: °C
* Weather information on route, provide by Open Weather Map.
All Rights Reserved. © 2010 - 2016 About Feedback


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One Direction's Harry Styles Dines with Pretty Blondes in London
Crystal Bell
| August 28, 2012 - 11:57 am
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Canes Baseball Climbs Top 25 Rankings
DURHAM, N.C. --?The Miami Hurricanes climbed three spots in the newest?Baseball America?top 25 rankings released Monday, jumping to No. 13 in the weekly poll and matching their highest ranking from the publication since April 9, 2012.
Miami used a perfect 5-0 week, including a sweep of visiting Boston College in the opening ACC series for both teams, to vault up the rankings. The sweep was the first of 2014 for the Hurricanes, who did not record an ACC sweep in 2013.
Beginning with Javi Salas' perfect game Tuesday against Villanova, Miami starters allowed just four runs in 34.1 combined innings this week (1.05 ERA).
The Hurricanes will carry a five-game winning streak - their largest since a 10-game stretch to open the 2013 season - into Tuesday's matchup with Bethune-Cookman (6 p.m.).
Miami, one of six teams from the ACC ranked in?Baseball America's weekly top 25, sits alone atop the Coastal Division at 10-5 overall and 3-0 ACC. The Hurricanes join Florida State (No. 2), Virginia (No. 3), NC State (No. 5), Clemson (No. 14) and North Carolina (19) in the weekly rankings.
To view the full top 25 rankings from?Baseball America, click?HERE.
SOURCE: Miami Athletics


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Created in this Craftsy class
Have your handbag and eat it too! Let celebrity cake designer Elisa Strauss teach you to sculpt and decorate an unbelievably realistic couture handbag from cake.
Other projects made as part of this class:
Offer some kudos...
Join the conversation...
Ask a question...
Add your comment...
|Here are some details about my project:
|Cake Decorating
|Any Occasion
|Royal Icing, Fondant, Gum Paste
Share a little about the materials, processes and techniques used to create this cake: Materials: 1- Recipe for Bobbie's vanilla-cherry blossom cupcakes Fondant Gumpaste/flower paste Petal/lustre dust Plum Larkspur Old gold Bronze Black Pearl Edible glue Water 1- Cup royal icing Everclear or lemon extract Small 6- petal set small,OP Equipment: Dresden tool, Fmm Quilting too, PME Scriber tool with diamond pattern handle, needed for hat Turkey tracer Silcone paint brush, color shaper Mini rollin pin Jewelry mold, JD Small bow mold, FI or you may create a small bow by hand 1.5 nozzle, PME Paper cornet or pipping bag (sandwich works too)] Artist brush #00 artist brush Variety of circle cutters Artrist knife A-ceto blade Pasta machine, optional
The purse, hat, hatbox and mirror can be constructed (larger version) on a cake..Perfect for Valentine's Day!
I love the attention to detail here. Brilliant work!


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Two new studies suggest that checking-account customers continue to be confused by banks' debit-card overdraft policies, despite Federal Reserve rules imposed last summer to protect card users from unexpected charges for overdrafts on point-of-sale transactions.
The new rules bar banks from imposing fees on such overdrafts unless an account-holder agrees in advance to the banks' terms. With typical fees of $35 per overdraft, banks have made billions of dollars a year by authorizing debit-card purchases even though there are insufficient funds in customers' accounts.


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- What Are Students Saying?
- Financial Aid
- How to Apply for Financial Aid
- WPU Scholarships and Awards
- Types of Loans
- Tuition and Fees
- Online Resources
- Forms
- Payment Options and Student Accounts
- First Year Students
- Transfer Students
- Re-Admissions
- Home Educated Students
- International Students
- Application Fee Online Payment
- Deposit Online Payment
- FAQs - Admissions
- Early Entrance
- Directions
- Meet the Admissions Team
FAQs - Student Accounts
When is my bill due?
Payments for tuition/fees, room and board are due in full by Aug. 1, for the fall semester and Dec. 15, for the spring semester.
Class registration may be canceled, at WPU's discretion, prior to the start of classes by the Registrar's Office if a student account balance is not fully satisfied by payment, financial aid and/or a payment plan.
If the total charges exceed the estimated aid, the student must pay the difference before the due date. If the aid exceeds the charges and there are no outstanding charges from a previous semester, the bill should reflect the overage in the "Amount Due" line and the student can expect a refund of the excess aid.
How is my bill delivered to me?
WPU mails one paper bill each semester to all students. If you have a balance due, you will receive monthly e-mail notifications reminding you to check your student account online at https://mypacernet.peace.edu
The eBill reflects all charges and credits on the student's account as of the date the bill was created. Note that the eBill is a snapshot of a student's charges at the time the bill was created. Any additional charges or financial aid added after the billing date will not appear on the eBill. New charges and credits can be viewed in real time on My.Peace.
How can I pay my bill?
WPU accepts checks, cash, money orders, Visa, MasterCard, Discover or electronic check payments.
Check and money order payments should be sent to:
William Peace University
Office of Student Accounts
15 East Peace Street
Raleigh, NC 27604
Families desiring to pay by credit card may pay online via our secure website. Students can login at https://my.peace.edu, click on the 'Students' tab, 'Financial Info,' 'My Account Info' and 'View Your Statement and Pay Your Bill.' You can also visit the Office of Student Accounts website. Students use the same login and password given to them by their advisors to register for classes online when logging in to pay their account.
Parents may also make a payment to a student's account without login information by visiting www.peace.edu and clicking on I am then a parent. Once there, click on 'Make a Payment on Account' tab on the left.
If you have misplaced your password, please contact the Office of the Registrar at 919.508.2012.
I can't pay my entire bill at one time. Are there payment options available?
WPU offers a convenient monthly payment plan with up to five equal monthly payments each semester. There is an enrollment fee of $30.00 each semester to participate in the plan payable at the time of enrollment. Students desiring to enroll in the payment plan may do so by going to www.peace.edu and clicking on I am and then a current student. Click on 'Sign up for the Payment Plan' in the menu on the left.
I am planning to attend as a full-time student, but am being charged for part-time tuition.
The charges on your account are based on the number of credit hours you are actually registered for at the time charges are generated. If you haven't registered for at least 12 hours, you will only have a part-time tuition charge on your account. If you plan to have at least 12 hours or more by the time classes start, be sure to pay based on the full-time tuition rate. If you think you should already be registered for at least 12 hours, log into your registration online to review or contact the Office of the Registrar at 919.508.2012.
I want to live on campus but don't see a charge for housing OR I don't want to live on campus, but am being charged for housing.
The charges for meals and housing are generated based on information in the Office of Residential Life. Contact them directly at 919.508.2014 for any questions you have regarding these items.
I have a charge for health insurance on my account, but already have health insurance from a different source. Can this be reversed?
WPU requires health insurance of all traditional full-time students. If you already have health insurance, you can waive WPU's insurance through an online waiver that will be available late June. Please check back to this location for a link to the site.
There is a student activity fee on my account. What is this?
WPU students pay a student activity fee each semester. The money received from student activity fees is allocated each semester by the SGA Finance Committee to help support programming on campus. William Peace University strongly believes in empowering students to make decisions that will positively impact campus life. Any questions regarding the use or allocation of student activity fees should be referred to the Vice President for Student Services, Frank Rizzo.
I have a credit balance on my account that I want to use for books. How can I access these funds?
Up to $750 per semester can be transferred to your PacerCard for use in the William Peace University bookstore. The PacerCard Financial Aid Transfer Form can be found on the Peace website by visiting the Office of Student Accounts. All excess funds transferred from the student account to the PacerCard must remain on the card, so plan on only transferring what you think you need. Transfers can be made as many times as necessary through the first four weeks of the semester.
Even after I transfer funds from my student account to my PacerCard, I will still have a credit balance. How can I access these funds?
WPU issues electronic refunds to all students with credit balances after the excess funds have been received by WPU from the lender. This process can take anywhere from a month to two months after classes start. Please plan accordingly if you are planning to use these funds for living expenses. Students can sign up for direct deposit by going to mypacernet.peace.edu and clicking on 'Financial Information' and 'Bank Information (U.S.).' You will be notified via email when the direct deposit has been made. Students who do not sign up for direct deposit that have excess aid over charges will have a check mailed to their home address on file.
I have questions about my loans, grants or scholarships. Whom do I contact?
Contact your financial aid advisor directly for all questions that pertain to financial aid. If you don't know which advisor is assigned to you, you can call the Office of Financial Aid at 919.508.2000 and they can connect you to the correct person.
I would like to make sure I don't lose any of the money I pay for tuition even if I have to withdraw during the semester. Is there anything available?
WPU is pleased to offer the tuition refund plan to students and parents. This elective insurance plan through AWG Dewar, Inc. provides coverage for tuition and housing charges should a student have to leave before completing a semester due to illness or accident. The insurance covers up to 70% of all tuition, housing and meals. To enroll in this plan return the bottom portions of the letter received from Dewar, or visit the Office of Student Accounts website.
I would like to have my car on campus. What do I need to do?
An annual parking decal can be purchased that allows students to park on campus. All decals must be purchased online by going to www.peace.edu and click on I am and then a current student. Click on 'Purchase a Parking Decal' on the left menu. Prepaid decals will be distributed on move in day to residential students. Commuters can pick up their decals in Main 116 during the first week of class with a photo ID.
If I have questions, who should I contact?
|Classes and Registration
|Health Insurance Waivers
|Student Accounts
|Housing and Meal Plans
|Residence Life
|Financial Aid
|Payment, Payment Plans, Parking Decals
|Student Accounts


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This first edition of the ACUS sourcbook, originally published in December 2012, was corrected in March 2013 prior to a second printing. For a full list of corrections, please see page vi.
The ACUS sourcebook examines the agencies and other organizational entities of the federal executive establishment, including independent agencies. The results of this study are an especially valuable resource to Congress, the judiciary, individual agencies, the general public and academic researchers in government and public administration. No other up-to-date resource of its kind exists.
Click here to view the complete data that provide the basis for the Sourcebook on the Vanderbilt University website. The website includes links to: (1) the data (in Microsoft Excel format), and (2) the complete codebook describing the data (with a 238-page appendix including all relevant statutory citations and language).


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Valkyria Chronicles 2 Review
For those looking for a stylish, intellectually stimulating strategy game, Valkyria Chronicles II won't disappoint.
Grids, menus and stats; not the most exhilarating things in the world are they? Still, throw them all together with a suitable anime aesthetic and appropriate rags-to-riches narrative, and the resulting blend can be thoroughly engrossing. The trouble is, however, this is the exact formula the SRPG genre has used for years. It's always the same. You move your rag tag army about a grid, issuing commands which they'll execute based on some dice-rolling going on behind the scenes. Back in 2007, Valkyria Chronicles broke that mould. It was exactly the kind of innovation the SRPG needed, and reignited interest in a genre that was starting to get stale. The game was released to critical applause, and following an anime, its own Manga and incessant babble from people like me who couldn't shut up about how good it was, a sequel was always inevitable.
Taking place two years after the original, in the January of 1937, Valkyria Chronicles II follows a class of cadets during the midst of the Gallian Civil War. Set in and around the grounds of Lanseal Academy, players take control of the comically useless Class G, who turn up late to lessons, fall asleep at their desks and continually embarrass their teachers. This year's ambitious young lieutenant (or Class Chair) is Avan Harkins - an overly peppy youth who enlists at Lanseal to investigate the death of his brother, Leon. While likeable enough, Avan doesn't possess the same naive charm as VC1's Welkin, but he remains an appropriate vessel to carry the action nonetheless.
For the aspiring general, Lanseal Academy is more of a holiday complex than a school; the perfect place to research new weapons, train at the drill grounds or simply ponder over future strategies. In between missions players can select different parts of the Academy to explore, where members of Class G are always loitering about, ready to further the narrative. The story is conveyed through static but well-drawn 2D cutscenes, where Avan and his chums will converse in comic book speech bubbles. It works well with the game's gorgeous watercolour visuals, and saves the PSP from too much technological labour.
Despite the fact it's little more than a glorified map screen, Lanseal Academy is brimming with atmosphere and personality. The story arcs hiding beneath its beautiful architecture are quite different to those of the first game, however. Given the youthful and woefully carefree ensemble of cadets advancing the plot, Valkyria Chronicles II lacks the importance and urgency that underpinned the first game. The storytelling centres around school yard crushes, bullying and class rivalry, themes that many gamers might associate with the Persona series. For fans of the first game who particularly liked the WW2 theme and adult character development, this might seem a little immature in comparison.
That said, the action on the battlefield remains as sophisticated as ever, with layer upon layer of tactical opportunity wrapped around the series' genre-breaking approach to combat. Before jumping into battle players are free to choose which six characters they'd like to send into the skirmish, and where they should be deployed. Characters fall into one of five classes, four of which make a return from the first game. Scouts can cover the most ground of the four classes, and have a keen eye for spotting hidden enemies. Shock Troopers are your frontline fighters, equipped with machine guns for improved firepower. Lancers are well-equipped to take down tanks, and Engineers can be used to heal allies and repair tanks. Finally, the new class to the series are Armoured Soldiers, who carry huge shields that can deflect machine gun fire. While they don't carry a weapon themselves, they also have the helpful ability to disarm mines.
Fans of the original might be distressed by the absence of the Sniper, but fear not - it's still in the game as a sub branch of the Scout class. Through gaining experience and merits, players can direct a character's training through a branching class tree. Each class might feature six or so sub-classes, giving a range of different alternatives to defining your squad. On top of this, Valkyria Chronicles II includes much more comprehensive customisation features, especially when it comes to vehicles. Like its predecessor, VCII gives players a tank to roll into battle (you can name it too - mine's called Thor), and this time it can be tailored to such an extent that you can strip it down to a simple armoured car, or turn in it into a hulking steel behemoth capable of destroying entire towns.


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I needed to integrate a calendar into my application.
This being a CakePHP application, I started looking for a good calendar helper – but found none that I liked enough to integrate. Luckily, I then stumbled upon the excellent fullCalendar project which is everything I wanted:
- Extensible – let me change events easily.
- Provides lazy loading of events.
- Provides for visual differentiation of events based on their type.
- Uses multiple displays (daily, weekly, monthly).
- Lets me, as the developer, store events that are not editable by the user (e.g. Easter dates).
Integration with Cake was relatively straight forward, and I found this series that helped me get started.
FullCalendar is a jQuery plugin. To use it, you'll need jQuery library itself and a few jQuery plugins. You don't need to go and find them all over the Internet – they are all bundled with the fullCalendar download.
To set up your cake with fullCalendar you'll first need to download and unzip fullCalendar's download package to cake's /app/webroot/js folder.
Then you'll want to hook up fullCalendar's css and javascript files to your page. It's pretty straightforward actually. You may use the Javascript helper or add the script tags to the view file yourself.
To use the Javascript helper, add it to the $helpers array in your controller (my calendar controller is just called events_controller):
class EventsController extends BaseController { var $name = 'Events'; var $helpers = array('Admin','Time','Javascript'); }
Then link the relevant javascript files in your view. I just add them to the relevant *.ctp file (calendar.ctp in my case) – but you may add them to the layout itself if you want.
 <?php echo $javascript->link('jquery-1.3.2.min.js'); echo $javascript->link('ui.core.js'); echo $javascript->link('ui.resizable.js'); echo $javascript->link('fullcalendar.min.js'); echo $javascript->link('ui.draggable.js'); echo $html->css('fullcalendar'); //Note: to use $html->css as above, the fullcalendar.css //file must be in your app/webroot/css folder. ?>

The "calendar" div above is the where the fullCalendar will actually be created once you call the fullCalendar function in your document.ready function
3. To display the calendar, you need to call its init method – fullCalendar.

The code above will display the calendar with its default configuration. It will have no events, because none are defined.
If you did everything right you should see something like the screenshot below. This means that you managed to hook up fullCalendar and CakePHP.
And that's it for integration.
The next post in this series describes how to hook up a database table as an events source for this integration.


text: This is totally OT, and it's not even a Useful Resource (unless you find it Useful to have a good laugh about something totally silly). http://www.youtube.com/watch?v=q5sq0am3HdI I probably have a simpleton's sense of humor but this cracks me up however often I watch it. The last few seconds alone are priceless, the way it says 'Papple' after humming a snippet of Papageno's bird catcher aria. Absolutely brilliant Or maybe it's just my bad taste.


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Title IX and Upward Bound to be discussed
Title IX education and Upward Bound Math and Science programs will be discussed at the American Association of University Women's meeting at 10 a.m. Saturday at the Waterfront in the Maalaea Harbor Shops.
At 11 a.m., Alvin Tagomori, University of Hawaii Maui College vice chancellor of student affairs, will speak about Title IX of the Educational Amendments of 1972, which prohibits sex discrimination in educational programs that receive federal funds.
Following Tagomori, Melissa Bonnin, project director for Upward Bound Math and Science, will discuss a new federal grant to UH that prepares low-income, first-generation high school students for entry into science, technology, engineering and mathematics college programs.
Lunch is at noon. For information and reservations, contact Cheryl Bergman at 244-1850 or firstname.lastname@example.com.
Uluwehi Guerrero performing free concert
Roselani Place and Ola Na Mele Productions will present their ongoing "Picnic for Poki" concert series at 11 a.m. Thursday at the Kaahumanu Church in Wailuku.
The featured musical guest will be Na Hoku Hanohano award winner Uluwehi Guerrero with Halau Hula Kauluokala.
Guerrero entertains with traditional and contemporary Hawaiian music and hula. His 1996 CD "Ka Manawa Pono" received three prestigious Na Hoku Hanohano award nominations. In 2009, Guerrero released a CD of Hawaiian favorites, "Uluwehi Sings Na Mele Hula Aloha - Beloved Hula Songs."
Attendees may bring their own lunch, and fresh-baked cookies provided by Roselani Place will be available. The hourlong free event is open to the public. The church is at 103 S. High St. For more information, call 871-7720.
Read Aloud America to offer program
The Maui Mall Family Fun Sunday on Feb. 24 will include a read-aloud session for keiki, preschool to 2nd grade, beginning at 1:45 p.m.
The free read-aloud session will be held in one of the spaces in Maui Mall.
Joanne Laird, program director for Read Aloud America, will read from picture books. At the conclusion of the Read Aloud session, participants will be served free healthy snacks and treats sponsored by Whole Foods Market. Each child will also be able to select a free, brand-new book to take home.
This 40-minute program will conclude with a grand prize drawing for a child and adult winner. Children must come with a parent or care-giver.
Lion dance will be performed today
A lion dance will be performed at about 5 p.m. today by Ben Seng Au's Shaolin Arts Society troupe at The Old Wailuku Inn at Ulupono in Wailuku.
The performance is free. The inn will provide lai see (red envelopes) to those who wish to "feed the lions" in hopes of ensuring a healthy and prosperous new year.
The inn is located at 2199 Kahookele St. For more information, call the inn at 244-5897.
Hazama to emcee Minnesota reunion
The 24th annual Minnesota Reunion and Potluck will take place from 11 a.m. to 2 p.m. Saturday at Kalama Park in Kihei, across from Foodland.
Participants may bring a Minnesota hot dish, wear a Minnesota T-shirt and speak Minnesotan.
Maui-born-and-raised Chuck Hazama will be the emcee. He served for several years as the mayor of Rochester, Minn.
Ice fishing stories and other Minnesota tales will be shared. For more information, call 572-0964.
School anniversary topic of meeting
A meeting to plan Baldwin High School's 75th anniversary celebration will be held in the school's new library at 5 p.m. Feb. 26.
The festivities will take place in October.
Alumni, staff and other individuals interested in helping to plan the anniversary events are encouraged to attend this planning meeting.
For more information, contact Lynn Araki-Regan at 280-1299 or email firstname.lastname@example.com.
Kula AARP Chapter to meet Monday
The regular meeting of Kula AARP Chapter will take place at 9 a.m. Monday at the Kula Community Center. The meeting will begin with refreshments, followed by a business meeting at 9:30 a.m.
Marlo Chapman, from Kalama Heights Retirement Community, will share information about what the facility offers, including activities.
The meeting is open to the public, and reservations are not necessary. Members and guests are encouraged to bring food for the Maui Food Bank, the chapter's ongoing community service project.
For information, call Diane Logsdon at 878-3448.
Visit to Vietnam topic of presentation
Longtime Rotary member Ron Harris will speak about his recent trip to Vietnam during the Kihei/Wailea Rotary Club meeting at noon Wednesday.
The cost for the lunch meeting at Mulligans on the Blue is $16. The public is welcome.
Lahaina children feed dancing lions
Traffic on Front Street came to a halt Wednesday when firecrackers were lit at the entrance of The Wharf Cinema Center to waken the sleeping lions and ring in Chinese New Year, the Year of the Snake.
Spectators lined every level of the shopping center as dancing lions made their way to center stage, where more than 300 of Lahaina's children waited for their appearance.
Au's Shaolin Arts Society martial arts demonstration and lion dancing kept the attention of spectators, which included area schoolchildren.
Hotel association director to speak
Lisa Paulson, executive director of the Maui Hotel & Lodging Association, will be the guest speaker at the Rotary Club of Maui's meeting at noon Thursday.
Paulson's presentation will be about the hotel and lodging industry and its legislative needs, community events and goals.
Paulson assumed her position with the Maui Hotel & Lodging Association in October 2012. The club meets at the Class Act Restaurant at UH-Maui College. The cost is $20. The public is welcome.


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Minnesota Electrician & Energy Trades Technical Schools:
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Technical Schools Guide makes finding the right Electrician Training School in Minnesota simple. You can also find electrician schools available throughout the United States. We list both large and small Technical Colleges throughout the United States. Whether you are planning on attending a 2-year college, 4-year college, vocational college, purely technical college, or just single college courses, the listings above should contain each type of trade school, college, or university. Financial aid is available for many of these colleges but visitors will need to contact each school directly to get assistance. Technical Schools Guide does not maintain specific course, tuition, application, accreditation or records of information on specific schools. All inquiries should be made directly with such schools. All information contained above is believed to be accurate and reputable. If a discrepancy is found, please contact the Technical Schools Guide staff by clicking on the "contact us" link below. We are also able to update college information and locations through this contact address. Featured listings on Technical Schools Guide are generally for-profit school listings. These listings help pay for bandwidth and maintenance of the Technical Schools Guide site. Thanks for visiting Technical Schools Guide and good luck in your Minnesota Electrician Training School experience!
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text: The handsome red-brick Melford Hall dominates the north side of Long Melford's village green. Badmin had already included it in a view of the green, but here he focuses on the house itself. His typically tight and meticulous handling of watercolour suggests the bright sunlight and strong shadows falling on the house facade in the afternoon. Melford Hall was originally built around 1560 and after the war became the property of the National Trust.


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A fugitive wanted in several states was arrested in southern Indiana on Wednesday night.
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Make Selfie Bracelets with your photos using our iPhone app…
Just use your imagination and craft a fashion statement as unique as you are!
Upload your pictures!
MyPhotoSizer makes it fun and super easy to upload and crop photos from your computer! Then, it automatically assembles a downloadable photo card with images ready to cut out and place on your Image Bracelet!
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Instructions in Additional Languages
My Image Bracelet Maker® Refill Kit
The My Image Bracelet Maker® Refill Kit has everything you need to keep your wrists updated with fabulous and funky flair! The IBM Refill adds glam with GLITTER tiles in 6 colors, along with brand new art cards, glue, and elastic bracelet strings.


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March 12, 2007
Elsevier MDLLars BarfodPresident & CEO
How has your company adapted and responded to the changing economic climate in the past five years when so many others companies did not?
Elsevier MDL delivers informatics solutions with real business value rather than just technology clout. The new scientist-centered MDL Isentris system integrates information access and workflow applications for improved decision-making in R&D. Five years ago people thought about Isentris as a technology platform. Today it's a business-enabler and a problem-solver that meets bottom-line business requirements. Our customers want to work more efficiently, save time, save costs. To thrive in today's economic climate, we're operating more cost-effectively ourselves by using offshore development resources, and we're passing savings on to customers by aligning our pricing policies with our customers' budget situations.
What is your vision for the future of the life sciences market over the next several years?
We're already seeing several large pharmas synthesizing compounds in lower cost areas of the world. This globalization of pharmaceutical R&D will continue with many companies collaborating with offshore R&D sites in India, China, and other countries where costs are lower. As a result, we are also seeing an increasing need for improved integration of data, workflow, and business processes across, and between global enterprises. MDL Isentris is aligned with this business paradigm. Isentris improves the integration of data and workflow applications and offers greater cost efficiency and improved security and performance over wide area networks.
What products and services does your company provide and what special capabilities do they offer the life sciences market?
Elsevier MDL provides the informatics infrastructure, content and decision support software that scientists need to do efficient discovery research. An integrating solution like Isentris optimizes successful, enterprise-wide R&D. Our DiscoveryGate content service puts information at scientists' fingertips, enabling them to conduct better-informed investigations. Workflow solutions like MDL Notebook, MDL Registration, MDL Logistics, MDL Assay Explorer and MDL Plate Manager help scientists manage their experiments efficiently. At the level of the individual scientist, we help global teams capture, register, analyze, report on and share data. At the enterprise level, we help organizations create, capture and protect the intellectual property that is the foundation of everything they do.
Partnerships are an effective way to track life science advances and ensure that your company delivers timely products and services. Which life sciences companies or organizations have you partnered with or invested in and why?
Content is a key partnership area for Elsevier MDL. Our DiscoveryGate platform gives scientists access to 22 databases covering bioactivity, sourcing, synthesis, drug safety, and pharmacology information including content from providers such as Prous Science and FIZ CHEMIE. DiscoveryGate also provides access to indexed compounds referenced in PubChem and the Derwent World Patents Index. Another major partnership area for us is the MDL Isentris Alliance. This is a community of partner companies such as Spotfire that is developing integrated, high-value solutions for researchers using the open Isentris system. The Isentris Alliance is one more way we spare customers the headache of having to integrate disparate applications from different vendors themselves.
What are your most exciting products and initiatives in development, and how will they improve life science research?
We are aggressively developing our new Isentris informatics and workflow integration system and expect to deepen and widen its applicability along the R&D value chain. For example, the Isentris-based MDL Notebook ELN is leading the way in extending data and workflow integration capabilities into chemistry and biology — providing improved patent information, logistics support, and reagent, compound, sample and assay management, both for low-throughput and high-throughput screening.
Where do you see your company in five years?
Elsevier MDL will continue to be the leading provider of integrated informatics solutions for research and development with an even stronger focus on partnering with customers to improve performance and cost efficiency. By extending the benefits of enhanced integration into the areas of preclinical and clinical development and actively participating in much-needed consolidation within the IT industry, we will continue to lead the way in pioneering cost-effective informatics solutions that improve the efficiency of the R&D process.
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text:
As Immunotherapy Revolutionizes the Cancer Treatment...
Quadruple Helices Appear To Have Role...
LC-MS Gains Favor Due To the...
Wall Street Decline Takes Its Toll...
From Ilya Mechnikov discovering phagocytosis in starfish larvae to Hodgkin and Huxley defining the principles of nerve conduction in the giant axons of squid, aquatic animal models have influenced our understanding of human biology for over 100 years.
Yet the power of these marine models extends past the realm of basic biology and into the sphere of translational medicine, offering unique versatility for pathogenic exploration that cannot be found in other animal models.
This facet was on marked display at the "Aquatic Animal Models for Human Disease and Midwest Zebrafish" conference held at the University of Wisconsin-Milwaukee School of Freshwater Sciences in July.
Simplicity and a diversity of tools are the prominent advantages of aquatic models of human disease, according to developmental biologist Anthony De Tomaso, Ph.D., associate professor at the University of California, Santa Barbara.
Such is the case with his study of Botryllus schlosseri, a star-shaped invertebrate whose extracorporeal vasculature—coursing along the surface of its body—allows for direct examination of the interactions between immune cells.
"Basically it is a simplified model for understanding self/nonself recognition or allorecognition," said Dr. De Tomaso. "Our [human] immune cells are running around inside of our bodies, while in Botryllus, the cells are outside the body. Thus you can touch them or watch them come into contact with each other, all within two sessile cell layers."
Allorecognition enables genetically compatible Botryllus tunicates to form colonies, but also features in fusion-rejection pathways that functionally mimic how the human body accepts or rejects organ transplants.
In humans, allorecognition is governed by the major histocompatibility complexes, which are the most diverse gene family in vertebrates. In contrast, histocompatibility in Botryllus is governed by single locus—fuhc—that encodes two highly polymorphic genes. Dr. De Tomaso has uncovered that these two inputs let Botryllus' cells "integrate multiple signaling events from the cell surface and make a decision on a response."
These pathways have been highly conserved throughout metazoan evolution, suggesting that understanding chordate histocompatibility can provide clinically relevant information on immune processes such as tolerance and education, especially for natural killer cells, according to Dr. De Tomaso.
Another translational feature of Botryllus involves a fierce competition between the stem cells of two tunicates fusing into a new clonal chimera. In some incidents, circulating stem cells from one animal will try to hijack the germline or somatic cells of its new partner.
This cellular parasitism hearkens to the aggressive nature of malignant tumors and cancer stem cells.
"The Botryllus system has a natural situation where variation in stem cell properties—growth, migration, competition—provides a definite correlation to why one stem cell population is better than the next," said Dr. De Tomaso. "This is the other biomedical aspect of our work. Botryllus could provide clues as to why some cancer stem cells are better at migrating or self-renewing."
While histocompatibility represents an immunological definition of self, people are most cognizant of the identity defined by their mental awareness, especially their memories. This is most pertinent in the clinical realm of Alzheimer's disease and other forms of dementia.
New dimensions of neurobiological aging are being revealed by research with the seaslug Aplysia californica in the laboratory of Lynne Fieber, Ph.D., associate professor of marine biology and fisheries at the University of Miami. Based across the street from the NIH/University of Miami National Resource for Aplysia Facility, Dr. Fieber's team of marine biologists has uncovered novel insights into age-related declines in glutamate signaling.
"We're trying to understand the fundamental differences between sensation and motor activity," said Dr. Fieber. "When you feel pinch or heat on the tip of your finger, how does that reflex age?"
Over the last two decades it has become clear that changes in sensory and motor function are associated with Alzheimer's disease, especially at early or presymptomatic stages of the condition. Reductions in glutamate levels within the nervous system are a classic hallmark of aging in both humans and Aplysia.
Aplysia offers a great context for neurobiological aging studies as its entire lifespan is completed within a single year. In addition, its nervous system is rather small (20,000 neurons) in comparison to humans (85 billion neurons) or animal models such as mice (75 million neurons). Thus there is nearly a one-to-one correspondence between sensory neurons, motor neurons, and muscles, which provides better resolution for deciphering neural circuits and electrophysiology.
"The organization of the nervous system is different in invertebrates compared to vertebrates. Nevertheless at a basic level, there are very conserved physiological and neurological phenomena that are present in both kinds of animals," said Dr. Fieber, who noted that Eric Kandel's groundbreaking research with Aplysia demonstrated how neurons are able to form and store memories.
Dr. Fieber is capitalizing on the power and simplicity of this model to examine D-aspartate, a chemical in the nervous system that is emerging as a possible endogenous agonist for glutamate receptors. She began the project a few years ago in collaboration with neurobiologist Antimo D'Aniello, Ph.D., of the Stazione Zoologica (Naples, Italy). Dr. D'Aniello has found that free D-aspartate in the brains of humans radically changes with age.
While D-aspartate can substitute for glutamate at certain synapses, it appears that the compound also activates an unidentified receptor in mammals and Aplysia. Dr. Fieber is now conducting a search for this unidentified glutamate receptor.
Cognitive prowess is not the only line of aging research to benefit from aquatic models. John Postlethwait, Ph.D., professor of biology at the University of Oregon, is studying ancient Antarctic icefish to find clues as to why bones lose mineral density over the course of lifetime, a condition known as osteopenia.
Although less severe than osteoporosis, this bone condition is nearly three times as prevalent in people over the age of 50. Nearly four out of five cases are associated with acute pain, and 25% of women with osteopenia will sustain a vertebral compression fracture.
Instead of occurring over developmental time—80–90 years for humans—bone density was lost in Notothenioid fish lineages over the course of 10 million years. As the waters cooled along the coasts of Antartica, the rich fauna near the shore of the island continent began to die off and were replaced by the bottom-feeding—benthic—Notothenioids. However these fish lacked a swim bladder, a lung-like sac that allows fish to regulate their buoyancy. So to complete their upward migration, Notothenioid species either acquired the ability to produce more lipids or lost mass from their bones, which are the most dense organs in the body.
How does evolutionary progression with icefish relate to age-related osteopenia? More buoyant icefish lineages retained their genes for bone mineralization, but changed how they regulate these genes, which is a scenario that mimics bone density loss in humans.
"The two processes, in humans and icefish, are the same," said Dr. Postlethwait. "We know that most people don't have mutations that completely block bone mineralization. What they have are mutations that dysregulate the control of bone mineralization genes."
By comparing the genetic profiles of poorly and robustly mineralized fish, Dr. Postlethwait's team hopes to isolate regulatory gene regions—enhancers, promoters, and repressors—that are responsible for maintaining bone density.
These findings could be used to improve the resolution of genome-wide association studies (GWAS) of skeletal profiles, which have identified about 60 loci of previously unknown function.
"The problem is many or most of these identified genetic loci are out in the middle of nowhere. They are near genes but not in coding regions," said Dr. Postlethwait. "If we can identify specific regulatory elements that are responsible for bone mineralization dissonance in the Antarctic icefish, we can then search for similar elements in humans."
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While Zika continues to garner a lot of news coverage, a Mayo Clinic survey reveals that Americans believe the country's most significant healthcare challenge is cancer. Compared to other diseases, does the possibility of developing cancer worry you the most?
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31 years of experience
Accepting new patients
Video profile
2501 E Chapman Ave
Orange, CA 92869 Phone number & directions
Patient Reviews
Patient Reviews ? Write a Review
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Dr. Norman Rosen himself is a fine doctor, has a quiet but overall caring manner. However, his office is run very badly: long waits on the telephone to make appointments, long waits at the office to go into your appointment, confusion by staff on the phone when you try to follow up on appointments, prescriptions, etc.
Dr. Rosen is extremely thorough. He listens carefully and respectfully, does a complete exam, and accurately pinpoints the problem. Dr. Rosen also has excellent suggestions (which I follow) that have improved my overall health. I know that I am receiving the best possible medical care.
He could be a great doctor when he wants to be, if he is busy or in a bad mood he doesn't want to listen to what his patients have to say. He has been my doctor for years, but this last visit will be my last, I went in for a physical and he was rushed not in a good mood due to what seemed like a nurse in training, during the internal portion of the physical he poked something wrong which was very painful at the time and I bled all weekend. His bedside manor is hit or miss, I'm tired of the misses.


text: This progressive couture house-turned-cult fashion favorite first leapt onto the international scene with Hubert de Givenchy's forever-chic, cutting-edge designs. Today, Givenchy's innovative spirit lives on in Creative Director Riccardo Tisci's directional vision. SHOP: GIVENCHY FOR WOMEN Title: GIVENCHY FOR WOMEN ExternalLink: c/givenchy-women?campaign=0222boutiquep01 SHOP: GIVENCHY FOR MEN Title: GIVENCHY FOR MEN ExternalLink: c/givenchy-men?campaign=0222boutiquep01