text:
God's Freedom Rally
I received an email invitation this morning and it really got me thinking. Why is it that we seem to need a specific time and place to be the people that God has called us to be? As Christians, we should start every day with the same excitement and hope of Christ-centered results as if we were attending a big rally! I've copied the email below, and I've made a few adjustments and comments. I pray that this will prick your heart as it did mine.
From: Father, Son and Spirit
To: YOU
Sent: Tuesday, March 20, 2012 4:24 PM
Subject: God's Freedom Rally
Please forward to all Christians everywhere
Chapters and members:
FREEDOM OF THE ROAD RIDERS (FORR) Father, Son, and Spirit have a rally in Buckhorn, MO your town, every day of each year on Memorial Day.
For years,
CMAChristians has have been working very hard at this rally. Please pray and see where God would like you to participate in this ministry. It varies in many areas, but our colorsattitudes speak volumes - including:
· Hospitality area – munchies, coffee, tracts - Are you hospitable to the world, drawing them close to you, or do you push them away hoping someone else will take the time to minister to them?
· First Aid - How often do you stop to help the hurting?
· Restroom supply baskets in each restroom/shower - Do you make yourself available for the jobs that nobody wants?
· Tractor driver - Do you lead people to their destination, or just let them wander to find their own way?
· Trailer rider/helpers – Do you disciple others so that they can become tractor drivers also?
· Sunday Service on stage - Do you attend and support your local church regularly?
· Music on stage Sunday morning - Do you publically praise God for His blessings, both in church and out?
· Hand out tracts/Bibles during Sunday service - Do you actively participate in your local church? They need you!
· Bike blessing teams – Are you known as "the person who will pray for me?" Bikers seek out people to bless their bikes, is anyone looking for you for prayer?
· Prayer walkers – who do this in 'Sniper' mode - Do you pray for your co-workers or people you pass by in the mall or grocery store?
· Hog Roast meal a chapter prepares and serves to many - When was the last time you served at a homeless shelter or other help for the needy?
· Playing in the bike games & riding in poker run - Do you befriend the lost and spend time with them, or are they alienated because they may not be a "good influence"?
· Tourism – walk around admiring bikes, camps, and talking – pray w/ folks if asked to - How often to you work a street ministry? Do you talk with people walking by? Do you make the first gesture of kindness?
· Traffic directing – if needed in the parking, trailer riding part of rally - How often do you point people in the direction of their local church (or yours)?
· We prefer not be in the security jobs - Do you walk around and notice only what others are doing wrong?
· Homebound Prayer Warriors who pray for those out in the field - Do you lift your brothers and sisters in prayer DAILY? Each of us is on a battle-field. We all need prayer!
If you are interested and have any questions, please call or e-mail. We will do our best to help you in the area that God has set up for you to work.
Jesus' Love Rocks!
For a weekend rally we jump at the chance - why don't we do it every day? I challenge you to review the open positions, schedule a shift - then give it all you've got!!!


text:
Ellen DeGeneres visits Portia de Rossi's old school in Melbourne
- From: Herald Sun
- March 26, 2013
ELLEN DeGeneres visited Melbourne Girls Grammar this afternoon, the old school of her wife Portia de Rossi.
The superstar TV talk show host was at Melbourne Girls Grammar for about an hour and a half, filming segments for her American talk show.
She left around 3.15pm in the afternoon, to dozens of screaming school girls at the Anderson St entrance of the school in South Yarra.
DeGeneres headed straight back to the Grand Hyatt hotel in the city with Portia de Rossi after the school appearance.
Ellen DeGeneres and Portia de Rossi skip island getaway
DeGeneres and de Rossi arrived at the hotel around lunchtime, with a few dedicated fans outside with banners to welcome their hero.
She told fans it was great to be in Melbourne.
Pictures: Ellen DeGeneres in Australia
The pair arrived in a black van, with DeGeneres's mother Betty.
Earlier, DeGeneres tweeted: "G'Day Melbourne! So far I love it here, and all I've seen is the airport. See ya tomorrow! Come early to get a great spot!"
Colourful banners, costumes and T-shirts were on show as anxious fans braved up to 18 hours of sleeplessness and hunger to witness the talk show superstar's and her wife, Portia de Rossi's, arrival at Tullamarine.
Wearing a white wig to stand out die-hard Queenslander Brooke Saxby was hoping to finally hug her idol DeGeneres after making three attempts to try and catch her from LA to Sydney and finally Melbourne.
"She is the person I strive to be like and I just want to say thank you to her for that," she said.
By 11am "Go Ellen" chants were ringing around gate 23 as word of her possible arrival location spread like wildfire.
Ellen Express skips footy for Sydney beach
Fans formed a guard of honour lining the exit gates on either side at 11:15am singing and cheering.
A surprise appearance from former AFL player Warwick Capper shortly after donning a leopard-print shirt offered a distraction as the Ellen faithful rushed to get some happy snaps.
Lord Mayor Robert Doyle sent a welcome message to the stars on Twitter.
"Melbourne welcomes you and Portia to Melbourne! We hope you have a fantastic time here," he tweeted.
DeGeneres and her wife, Portia de Rossi, arrived on the Tullamarine tarmac in their special chartered Qantas flight, avoiding the public area.
The US talk show superstar tweeted: "Aboard my very own Ellen express to Melbourne! I hope @QantasAirways lets me fly it" just after 10am.
It's believed DeGeneres will go straight to her hotel in the city.
There are no official duties today.
DeGeneres confirmed the timing for her Melbourne show at Birrarung Marr on Twitter this morning.
She is urging fans to head to the area at 11am tomorrow where a stage is currently being constructed for the event.
The couple will be special guests at tomorrow night's black tie dinner at the Grand Hyatt hosted by Victorian Premier Denis Napthine, Swisse boss Radek Sali and Qantas chief executive Alan Joyce.
The guest list includes Tony Abbott's sister Christine Forster, who is flying in from Sydney for the night.
Forster, like DeGeneres, has been a vocal supporter of marriage equality.
The Herald Sun can confirm Geelong is no longer on the couple's itinerary.
"Due to the shortened trip, Ellen and Portia are unable to travel to Geelong," her publicist said.
"Geelong will be represented in the show's Melbourne event."
The Geelong-raised de Rossi still has relatives there, and the city had been expected to host the couple before DeGeneres changed her schedule because of illness.
DeGeneres had said on her top-rating US show she had wanted to visit a local pub at which de Rossi was a regular.
There was much excitement in Geelong for the homecoming of the city's most famous Hollywood resident.
The actor grew up in the suburb of Grovedale before moving to Melbourne in her early twenties and then on to Hollywood. She was then known as Amanda Rogers, but later changed her name.
With Brendan Lucas
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Lolly Posted at 1:02 PM March 25, 2013
Love you Ellen!

subset: commoncrawl


text:
Thank you for visiting our past auction result archives. If you have an item identical (or similar) to this auction lot, please call, write or contact us to discuss. We will be able to help you.
Lot # 934 (of 1673) < Previous Lot | Next Lot >
Roderick Wallace Signed Black-and-White Hall of Fame Postcard
Starting Bid - $400.00 , Sold For - $3,818.75
Black-and-white (Artvue) Hall of Fame postcard of Roderick ("Bobby") Wallace, signed in blue fountain pen (grading "9") in the lower margin. Black-and-white Hall of Fame postcards were only issued between the years 1944 and 1963. Wallace was elected to the Hall of Fame in 1953 and passed away in 1960. This short window of opportunity for signing, combined with Roderick Wallace's relative obscurity and inaccessibility as a signer (though he would sign by mail - if you knew where to write, and had great interest, which few did) account for the rarity of his signature in general today, and in particular the rarity of his signed black-and-white postcards. The card displays light corner wear and a small area of surface paper loss on the reverse (the size of a stamp hinge and of no significance) resulting from the removal long ago of a small piece of tape relating to having once been mounted, otherwise in Excellent condition. LOA from James Spence/JSA. Reserve $400. Estimate $800+. SOLD FOR $3,818.75
(Click the smaller thumbnails to the left and right (if any) to cycle through each photo in the gallery of images for this lot.)


text:
Adapting to Evolving Business Environments Is...
Process Development Jobs Still the Most...
Nothing Beats Immunoassays for Sensitivity, Specificity,...
Quadruple Helices Appear To Have Role...
An oft-heard complaint in R&D is that technology can't keep up with the concepts that scientists are trying to prove or disprove. "In the case of biomarkers, having the technology is simply not the problem," says Daniel Chelsky, Ph.D, CSO of Caprion Proteomics. "In the last five years, mass spec has improved a bit, but only by about an order of magnitude in sensitivity. The technology is there, but most labs are not using it to its full potential."
According to Dr. Chelsky, we will be hearing a lot more about mass spec-based proteomics because the field has matured to the point where it can now have a significant impact on drug discovery, from both the perspective of discovering new markers and validating candidate markers.
At "Biomarker World Congress" to be held in Philadelphia next month, presenters will talk about advances in the field, and also consider the perks and pitfalls as biomarker validation finds its way to standardization.
Caprion has implemented three new tools geared to improve the success rate of biomarker identification. "Our main focus is on the use of multiple reaction monitoring," says Dr. Chelsky. "MRM allows you to multiplex up to 100 peptide candidates at a time, getting a very quantitative and convincing assessment and verification of candidate markers with speed, accuracy, reliability, and without the expense associated with discovery. This is why people are looking at MRM as the next step in mass spec-based proteomics and biomarker validation."
This approach can also be used for specific proteins. "Recently, a company told us that the sensitivity of its ELISA was not sufficient. In two weeks, we were able to develop an MRM assay using an antibody pull-down that could quantify their protein at 1 ng/mL in plasma. We can go much lower with small proteins and peptides, even without antibody pull-downs. The other advantage of MRM is its specificity that antibodies alone can't match."
And the lower abundance proteins are where the most interesting findings are. Dr. Chelsky notes that researchers have become more selective. As a result, Caprion has developed a way to examine secreted proteins by isolating golgi and secretory vesicles, breaking them open, and comparing the contents under different conditions.
"We'll look at diseased versus healthy, or treated versus untreated, and what we see in the 'secretome' will mimic what we later find in the blood. The advantage is that, when we isolate proteins straight from cells or tissues, they are highly concentrated and you know where they came from. We've been particularly successful with cancer because we have been able to get fresh human tumor tissue, especially in metabolic disease where people have been quite willing to give up some of their visceral and subcutaneous fat."
Depletion columns mark another difference. These columns can deplete the high and moderately abundant proteins in plasma, removing between 95% and 99% of the total protein, resulting in a 20-fold minimum improvement in sensitivity. "But proteins that are not normally present in plasma are also found after using these columns. These tend to be the ones that are most interesting and now there is a way of detecting them," Dr. Chelsky adds.
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text: Dale W. Schindler, 71, of Houtzdale died Friday. He was born in Gowanda, N.Y., son of the late Norman M. and Merle (Finch) Schindler. Surviving are his wife, Nancy P. Phillips; and six children: Sherry Bloodsworth, Randall Schindler, Todd Schindler, Melissa Schindler-Thornton, Heather Brown and Dennis Donaldson; and siblings: Hugh "Buster" Schindler, Clair Schindler, Bruce Schindler and Lela Struble. Friends will be received from 2 to 4 and 7 to 9 p.m. Monday and from 9 until the 11 a.m. funeral service Tuesday at the Kruise Funeral Home Inc., Madera. Pastor Robert Ford will officiate.


text:
Ithaca – A steady trickle of emails for Cornell University President David J. Skorton carried the same query. Whether they were from friends in the Pac-10 Conference, the Big Ten or dressed up with fancy words from colleagues in the Ivy League, each kept asking, "What is going on out there?"
As Skorton spoke to the gathering at Newman Arena on Tuesday, he said he responded to each email with a loud, spirited response.
"It's the Big Red!" he shouted.
The school stopped to recognize and celebrate its unprecedented success on the athletic playgrounds over the winter by its teams in men's basketball, men's ice hockey, women's ice hockey, fencing, wrestling and gymnastics.
Cornell director of athletics Andy Noel said it was the "most terrific single season in Cornell athletic history."
In the most recent updating standings for the Learfield Sports Directors Cup standings, Cornell is 54th . That's ahead of schools such as Syracuse (58), Clemson (61), Rutgers (67), Miami (77), Pittsburgh (82), Kansas (94) and 150 others.
When the next standings come out Thursday, Cornell should climb higher based on points from fencing and men's basketball. Later in the month's, men's hockey points will be added.
"You athletes have represented the university in extraordinary ways," said Cornell vice president for student and academic services Susan Murphy. "We have a lifetime of memories."
Here's what the celebration is about:
Fencing – An all-women's team finished 14th at the NCAA championship. Noel said it's an event in which men's and women's scores are combined, so the women succeeded "without the men slowing them down."
Gymnastics – Undefeated dual meet season. Finished first in the Ivy League and fifth in the ECAC.
Women's ice hockey – Finished second at the NCAA, losing the championship game in double overtime. Won its first Ivy League title since 1996. Predicted to finish seventh in the ECAC and ended up first.
Men's basketball – Three-time Ivy League champions set a school record for victories (29-5) while advancing to the Sweet 16 of the NCAA championship.
Men's ice hockey – The Big Red was the ECAC tournament and regular season champion. It won 21 games while advancing to the NCAA tournament.
Wrestling – Finished second at the NCAA championship. Won its eighth straight Ivy title and had four wrestlers earn All-America honors.


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Physician Search
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Helping Younger People Better Understand Older People
From the tiniest, most fragile infants to older adults facing a variety of ailments, Lee Memorial Health System employees care for patients with the highest level of quality and compassion.
Sometimes—and not only in health care—if one has not experienced a particular health challenge, it may be hard to completely understand actions, emotions and perceptions of another person. This is especially true with younger people understanding the challenges facing older adults who are living with chronic diseases, disorders and illness associated with aging. To help foster greater understanding, our older adult services department created a hands-on training program called The SECURE Project for Sensitivity Training. Developed more than 20 years ago, the program helps anyone who works or interacts with older people better understand the experiences of aging.
"The program is focused on building compassion and empathy for what people go through as they age," says Teresa Frank-Fahrner, Lee Memorial Health System older adult services program coordinator. "The training addresses and provides a simulated experience for conditions like vision problems, dexterity issues and arthritis. While this is extremely helpful for doctors, nurses and other health care professionals, we have found that many other companies and industries have purchased the program because they want to be able to better understand, improve sensitivity and support our growing older population."
The SECURE Project for Sensitivity Training program includes a DVD and CD; training manual; handouts with exercises; glasses that simulate eye problems like glaucoma, macular degeneration, stroke, cataracts, and yellowing of the lens; a pair of arthritis simulation gloves; a laminated number card; and a prescription bottle with "pills". All of these items—both the information and hands-on props—provide insight into common conditions of the aging population.
Not only is our nation aging, but Southwest Florida is twice the national average in older adult population. Thus the need to better understand the challenges of aging is even greater in our community.
"The growth of the older adult population is one reason why this training is so important," Teresa says. "But, it also is a good reminder to young people that how you take care of yourself today affects how you age."
Teresa also shares that the program has been sold throughout the country, as well as in Canada. "This has been our best year ever for sales," she shares. "Kimberly-Clarke—the sellers of products like Kleenex and Depends—recently purchased 9,000 kits to train their workforce throughout the country. Companies, along with other health care facilities and nursing schools, are realizing the importance of properly training staff to compassionately care for our older population."
Teresa adds that this sensitivity training helps remind us that older people were once young. "We ask people what they see when they look at an older person? Do they just see wrinkles, gray hair, ailments and illnesses? Or, do they see a person who has had a great life—a career, a family, wonderful experiences and interesting hobbies?" Teresa says. "We hope that this training provides a greater respect for our aging population—not just in what they can accomplish today, but what they have accomplished in their lives."
We are proud of the SECURE program and that it provides another opportunity to serve our patients by helping organizations and individuals learn how to adapt and compassionately serve the older generation.
Jim Nathan
President, Lee Memorial Health System
Jim Nathan,
LMHS President
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Our 1st book is out now • Find out more & order a copy »
this is sortof a collective piece. designed from a few different ideas that i have seen.
started with one big circle about 9- 10 inches diameter.
and cut two leaves either out of fabric or felt ..whatever you have on hand
and also one small circle the same size as the top of pot...for bottom of flower
stitch around outside of big circle loosely so you can pull tight and close
stuff with whatever you have...i used raw wool
close tightly and stitch secure
stitch button to center...pull needle through to the back, pull tight and secure.
then loop around to front and back through the center to the back ..like figure eights...make your pedals... however many you would like...i made six.
the leaves were done free hand on the machine . felt would work great in this step...hot glue the leaves on the back. take a circle the same size as the top of your pot and glue that onto the back to hide everything.
use two short lengths of ribbon as hinges. hot glue to flower and then to the inside of the pot. i also glued a small circle of fabric to the inside bottom to plag up the little hole...and then you just fill with your goodies and enjoy!
on this one i added a little button latch...and attached another short piece of ribbon under the flower to hook onto the button.


text:
Legacy of Kain: Soul Reaver for PCOn: PC
No description is currently available.
Stuck on Legacy of Kain: Soul Reaver? We've got you covered!
Don't panic! Our cheats will see you through.
Legacy of Kain has a '50/50 chance' of coming back
Still devs at Crystal Dynamics who "really want to make that game".
Footage of cancelled Soul Reaver successor Legacy of Kain: Dead Sun appears online
32 minute video of canned 360/PS3 sequel shows what could have been.


text:
Welcome and i hope you have fun here and with your wii!
Hi all just got my wifi working and i cant wait to try the channels out
Welcome and i hope you have fun here and with your wii!
Don't forget to give me a good reputation by clicking on
the mushroom thank you very much!
If you have any questions ask away!
Meow to you!....Now, say hello to my little friend:
^Thanks Monsteroids^
Spoiler Alert!
TNOG.ORG - Games events in Manchester
MikeDBloke - PSN
I was into weird games before people knew what they where
@D_Bloke - My inane prattle
Welcome to wiichat and enjoy your stay. Glad to have you on-board.
The key to immortality is first living a life
worth remembering. - Bruce Lee
PSN ID: Byuakuya


text:
How to Live Your Dreams
We're now officially back to normal. Of course, some will cry foul because this comic did run on cracked, but that's just the way my posting schedule works. Besides, I gotta admit, this particular comic is one of my favorite things I've ever written.
Reader Comments (33)
Welcome back, Lordship! I read your strips on both Cracked and here, so I get a double hit! Woo!
Too sexy for my car,
Too sexy by far...
Nicely done, Scott.
Welcome back!
Yay! I almost wasted away DX
Wow. I actually laughed out loud when I read Rick in panel 3. This one is hilarious.
Glad to have you back, Big M.
Is this a rerun? It's weirdly familiar.
Huh...I think this may be the kindest I've ever seen you be to Rick, from a writing perspective.
This Rick fellow is starting to look like a man of wisdom and expirience!
Even though I have read Cracked regularly since long before BI started appearing there, I only look at it on this site. Otherwise it just feels like I am cheating on you, Scott. Also, awesome job once again.
Double awesome since it's one of your favs. And yay for Rick for once, sort of. Welcome back!
I love how the conversations are EXACTLY the SAME, only VASTLY DIFFERENT. Great. Welcome back, Scott. Loved the reruns, but I'm glad to see new stuff.
Welcome back! And you've come back with a good 'un....
Deep stuff, man. I remember seeing Benny and Joon and thinking "She's crazy, that's so hot" and many years later and wiser seeing Howard's End and (alone among my friends) preferring Emma Thompson to Helena Bonham Carter insofar as "She's sane, that's so hot".
Woah, how is it that young Rick looks like he is the same age as young Rick, although he is about ten years older? :D
Also, John, it's not like Cracker are simply posting Basic Instructions without authorisation. It is part of a deal they have, so it's all good, I think.
I read the comics on Cracked and here. That way Cracked will continue to pay Scott that mad Webcomic money.
Glad you're back, though I enjoyed the superhero collection again, and the guest comic!
Today's is great, yet poignant - I'm still personally stuck at panel 2.
TMBG shirt ftw!
good to see you back Scott...enjoyed reading the reruns but Im waiting for some brand new shiny brilliance
If you want a color the police won't notice, my recommendation is metallic grandma green. I used to have one as a teen when the speed limits were 55. Even at 85, never stopped on the highway. It was great! Just like having a cloaking device!
Hah! If it's really a new comic then why does the copyright thingy say....oh nevermind.
With hair like that I can see why you shaved your head
I must have missed the comment thread controversy in re Cracked. (Can't say I'm sorry about that.)
Well, glad you got through surgery okay. You're not dead, so you must be stronger.
I did enjoy the Supers marathon. Toss in a cheezy Hostess advert and it would have been just like my childhood.
Welcome back, Scott.
I already posted this under the rerun of 'How to create a diversion', but it probably won't be seen by many people there: The Moon Emperor's plan seems to be coming closer to reality. On Saturday, Manchester United played at Soldier Field (home of the Chicago Bears), though the game wasn't against the Bears and I don't think Madden was anywhere to be seen.
Note from Scott: Thanks for helping prove, yet again that I am the Nostradamus of comics!
This comic reflects the old adage: 'If your not a liberal at 20 you have no heart. If your not a conservative at 40 you have no brain."
Nice to see the Flood shirt again. Personally, I've always been a "color the police won't notice" man myself.
Right said Fred, both of us together now
One each end and steady as we go.
Tried to lift it, couldn't even shift it
We was getting nowhere.
And so we had a cup of tea...
Oh... the shirt was for the band, not the song? Dang, I always liked that song. Sorry if I mucked up the lyrics, did that from memory (which is probably more disturbing than anything else).
Awesome strip, yet again! Great to have you back, Scott!
Welcome back!
This comic gave me the wonderful laugh I needed to brighten my day.
Thank you! :)
welcome back - hope everything is well on your world. Another great laugh = thanks!
Oh yeh... thats one of the gooduns! Welcome back.
I didn't know about the licensing with Cracked. Glad you are making money because I was worried you would start charging us and I am such a cheap bastid I would have a hard time convincing my wife to let me spend the money on this. thank you for keeping it free it's the best strip I have ever read.
Wow, that's so funny on a personal level because when I met my husband, I thought he was driving a strangly practical car for a young bachelor.
this one has to be the best one! !! for emphasis


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Pilot severely burned after crashing planeUPDATED 6:20 PM EDT Sep 11, 2013
A pilot is severely burned after crashing his plane--it's the third crash this year at the Smoketown Airport in Lancaster and all three planes have one thing in common.Video Transcript
3 NEWS FROM LANCASTER COUNTY. A PILOT IS SEVERELY BURNED AFTER CRASHING HIS PLANE THIS MORNING. IT'S THE THIRD CRASH THIS YEAR AT THE SMOKETOWN AIRPORT IN EAST LAMPETER TOWNSHIP. AS NEWS 8'S LANCASTER COUNTY REPORTER KATELYN SMITH LEARNED... ALL 3 PLANES HAVE ONE THING IN COMMON.3 JOSEPH BENDER IS LISTED IN CRITICAL CONDITION AT THE CROZIER CHESTER BURN CENTER. WITNESSES ON THE SCENE SAY HE WAS ALERT AND TALKING... WHEN HE CRAWLED OUT OF THE PLANE. BUT HE WAS IN A LOT OF PAIN. AN N-T-S-B INVESTIGATOR SAYS IT COULD BE A YEAR...BEFORE THERE'S A FINAL RULING ON WHAT CAUSED THE PLANE TO CRASH. HIS PRELIMINARY REPORT SHOWS THE PLANE'S ENGINE áDIDá HAVE POWER AT THE TIME OF THE CRASH.
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- Corylus maxima 'Atropurpurea Superba' (Purple Leaf Filbert)
- Elaeagnus pungens 'Maculata' (Variegated Russian Olive)
- Garrya x issaquahensis 'Pat Ballard'
- Lonicera fragrantissima (Winter Honeysuckle)
- Rhododendron mucronulatum (Korean Rhododendron)
Washington Park Arboretum
Center for Urban Horticulture
The UWBG horticultural crew will be making renovations to the southeast bed, which will include removing, relocating, or protecting other UW plant collections in the project area, followed by regrading of the bed and soil remediation. The 2009-2010 fall and winter planting of new winter-interest trees, shrubs, and ground covers will also take place.
This project will reclaim over 5,000 sq. ft. of bed space that is now detrimentally shaded by elm trees. It will also renew UW Landscape Architecture Professor Iain Robertson's original 1987 Winter Garden design intent.
This renovation was made possible by a gift from the Arboretum Foundation, which was given to them from Lake Washington Garden Club, Unit 3.


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By Kevin Davies
Sept. 5, 2008 | The headlines surrounding the pharmaceutical industry this summer have made for pretty grim reading. The specter of downsizing swirls around big pharmas such as Pfizer, GlaxoSmithKline, and many others. Drug safety issues have surfaced again with Biogen Idec's multiple sclerosis drug Tysabri. And the dearth of solid candidates in the pipelines is a key reason why pharmas are offering lavish sums for biotechs such as Genentech and ImClone.
Against this backdrop, the unprecedented model surrounding the creation and mission of Enlight Biosciences stands out a mile. As we report on page 10, Enlight is a technology development company cofounded by Merck, Pfizer, and Eli Lilly. The three pharma partners—one or two others may yet join—have invested in a for-profit company that aims to develop enabling tools and technologies for pharma customers. The founders will enjoy early access to those technologies.
Such precompetitive cooperation—or "co-opetition" as the business press calls it—could become a recurring theme in an industry badly in need of fresh ideas. It's an idea that has been tried in IT and health care before, although not always successfully. Years ago, several large insurers banded together to form MedUnite, an Internet company to handle health care transactions. It went bust.
Translation PointThe brainchild behind Enlight is Daphne Zohar, a founding partner with PureTech Ventures in Boston. "We focus on the translation of academic innovation," Zohar told me. Enlight was conceived a couple of years ago, when it was evident that most of the venture capital (VC) world had little interest in investing in new technologies. "[Technology] was outside the clinical therapeutic space," she says. "But some were potentially transformational, extremely exciting technologies that could really have an impact on the industry."
While attending a retreat sponsored by a VC firm, she sat through a panel discussion in which speakers bemoaned the lack of funding and incentives for investing in innovation. At lunch, she turned to Mervyn Turner, Merck's senior VP for licensing and external research, and asked what he thought. Wasn't he interested in those types of technologies?
Of course we're interested, Turner replied, we're very concerned about the trend.
"So what about having pharma work with us directly?" Zohar said. "Then we don't have to rely on the venture world," at least not initially. Pfizer and Eli Lilly soon jumped on board, while Zohar worked with PureTech partner (and Enlight's acting CEO) David Steinberg to nurture the idea. "There's definite interest from other pharma companies," says Zohar. A couple more may join, but not too many. "Just from managing relationships, it's a lot of effort, so we're probably going to cap it."
Zohar sums up Enlight's mission as, "The translation between preclinical, clinical, and point of care." The company will develop "technologies that will improve productivity by doing one of two things: either giving more information about a drug's potential efficacy and safety and/or technologies that translate across multiple stages of development, thereby providing really consistent, information which will again potentially lower the failure rate at the later stages."
Many of the specific technologies are about getting information earlier. Zohar checks off "all sorts of predictive models, imaging technologies, also technologies that can improve the performance of drugs or answer key bottlenecks." New forms of drug delivery will be another area of interest, such as delivery across the blood-brain barrier or improving the delivery of RNAi constructs.
It seems like a lot of ground to cover, especially as the founders are investing $39 million initially. That's not chump change, but it's not overwhelming either. As Derek Lowe wrote in his blog "In the Pipeline", "Those problems will eat $39 million without even reaching for the salt."
But Zohar calmly says that it's manageable. Aided by a stellar board of scientific advisors, led by MIT Nobel laureate Bob Horvitz and featuring world experts in imaging, genomic medicine, and medical devices, not to mention of course its founding pharma partners, Enlight will spin out a couple of companies a year. The first is an imaging company called Endra.
Zohar and her colleagues are excited about the Enlight model. "It's caught the attention of the venture world. We've got a lot of emails from colleagues saying it really makes a lot of sense." Which makes one wonder why they didn't try it before? For now, at least, many pharma companies have lots of money and a vital interest in addressing their pipeline problems. Perhaps Enlight's entrepreneurial spirit is exactly the incentive the industry needs.
This article appeared in Bio-IT World Magazine.
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With the start of a new school year just a week away, students aren't the only ones in the Lowcountry with the back-to-school jitters - teachers, too, are getting anxious.
First day of school
Aug. 18: Charleston, Dorchester 2 and 4
Aug. 19: Berkeley
And it's not only the first-year teachers; even some with decades of experience say they can't help worrying if their classrooms and lesson plans are ready.
"I still have the back-to-school nightmares," said Kelly Kennedy, an Alston Middle School teacher in Dorchester District 2 in Summerville who's been teaching for 25 years. "It's good because it shows the teachers are thinking about it and want to get off to a good start."
Every minute of every school day is considered precious these days, with districts, teachers and students under pressure to meet ever-changing educational standards. Teachers and students don't have the luxury of using the first weeks of a new school year to get back into the flow of learning.
Meta Van Sickle, chairwoman of the teacher education department at the College of Charleston, said the key to getting students learning as fast as possible is setting expectations and classroom routines right away.
"We always recommend you start that the first day, the first minute," she said. "Routines help you not lose time that's important for instruction."
Setting expectations
In Megan Profit's seventh- and eighth-grade math classes at Rollings Middle in Summerville, students get a say in what's expected of them. Profit said she and the students in each class work together to define academic goals and expectations for behavior.
Homework is non-negotiable, though.
"We do have discussions about why it's important to have homework," Profit said. "I usually ask them: 'Is really having no homework going to benefit you in the long run?'"
The list of expectations is turned into class contracts which each student signs.
"I think the reason I use that," she said, "is because it creates an investment from the child."
Former Berkeley High teacher Jessica Benton, who will work with other Berkeley County teachers this year as a mentor, said it was important that expectations and consequences were clearly spelled out with her 11th- and 12th-graders.
Benton also said she stressed the need to be professional and communicate clearly with her.
In elementary schools, expectations have more to do with behavior than academics and can take a lot of reinforcement. Laura Shaw, who teaches fourth grade at Charleston Progressive Academy in Charleston County, said typically the students at her elementary school are excited to learn something new. The challenge is teaching them all the day-to-day rules that will make it possible for them to learn.
Younger students often need reminding, Shaw said, of things like how to stand in line for lunch and how to enter the school the proper way.
"Being consistent and being on a schedule is so important for any grade," Shaw said.
"Find that bridge"
Pressure to make sure students are learning as much as they can weighs on teachers not just at the start of the school year but all year long.
"Teachers are always worried about getting the students to learn as much as is humanly possible," Van Sickle said.
But, inevitably, students need some review to dust off the summer cobwebs.
"Every teacher knows they are going to have to do a subset of review to build from," Van Sickle said.
Profit said she always starts her middle school math students with "baby steps" before throwing them a new concept.
"I always find that bridge from what they know to where we're going," she said.
Michael Petry, who teaches at Cane Bay High in Berkeley County, plans to have his 10th- and 11th-grade English students do a writing assignment the first day of school.
"It gives me immediate information to find out where my students are," Petry said. "It's really important that rather than jump right into new material that I establish a framework or benchmark (of students' skills)."
Most teachers agree that being flexible in the first months of school and meeting students where they are academically is key to getting them to learning more effectively.
"We don't teach students where we want them to be," Shaw said. "We teach them where they actually are."
Meeting students where they are is maybe more true in kindergarten than other grades because the students' skill levels can vary greatly, from students who can already write their name to others who are just using a pencil for the first time, said kindergarten teacher Kent Riddle, who will be teaching at the new Meeting Street Elementary at Brentwood school in North Charleston.
"I can set up instruction based on what I think they need to learn but if they don't know how to write (the alphabet) you're going to start there," Riddle said.
But perhaps the most important thing to getting a student of any age engaged in learning is making sure they feel a connection with their teachers.
"It's important that I immediately establish a rapport with the students," Petry said. "If they don't like the facilitator, if there's not a level of respect or a level of desire to be in front of that facilitator that's a hurdle to learning."
Reach Amanda Kerr at 937-5546 or at Twitter.com/PCAmandaKerr.
Jessica Benton (left), a teacher mentor, helps Ada Hill, math teacher, get her room ready at Berkeley High School.×
Jessica Benton, a teacher mentor, gets her room ready for the new school year at Berkeley High School.×
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HUNTSVILLE, AL -- More than 5,200 people have submitted their picks in The Huntsville Times College Football Pick 'em Poll. And with only three weeks left in the contest, several submitters are within a few wins of taking home the grand prize -- $300 cash.
We've been giving away $50 gift certificates to each weekly winner, but only the best will get the green. Here are the top 10 submitters for Weeks 1 through 10:
Mike Abell, 149-48
Phillip Banks, 149-48
John Doyle, 148-49
Billy Taylor, 147-50
Aaron Cain, 146-51
Ray Stephenson, 146-51
Bunk Bynum, 145-52
Jerry Burt, 145-52
Brent S. Bofenkamp, 145-52
Thomas Tefteller, 145-52
In the event of a tie, we'll draw a name at random to determine the winner. Click here for complete contest rules.
Want to know where you stand?that shows the complete rankings.
If you're in the running for the grand prize, make sure you submit your picks this week. You can find the Week 11 entry form here, or you can bookmark this link to keep up with the latest on The Huntsville Times College Football Pick 'em Poll.
If you have a question, e-mail us or leave a comment here.


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Friday Quick Links!
1. Alexander McQueen, Damien Hirst and the skull scarf via Yatzer
2. How about a corn husk wreath for Thanksgiving? via Design Improvised
3. Kris Knight's lovely paintings via The Jealous Curator
4. Curiots' mythical beasts via Colossal
5. Robert Larson turns everyday trash into art via design-milk
6. Fashion pays homage to some of art's greatest works via Honestly WTF
7. Loving Margo Wolewiec's fuzzy image textiles via Art Hound
8. Naomi Okubo's pattern filled art via Artsy Forager
9. Interview with artist and designer Emily Green via The Design Files
10. Adore these leaf rugs via Design Crush
11. Fascinated by Diana Scherer's Nuture Studies via Yellowtrace
12. Lovely wallpaper by Portland's Laundry Studio produced for Hygge & West via design*sponge
Contributed by Emily Gup


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In the last exercise, I showed you how to move paths and points around using the black and white Arrow tools. In this exercise, I am going to show you how to add and delete points from a path. I am still working inside that same Free-form polygon.psd file that I opened in the previous exercise. I have only moved a few points around, so no point in giving you an updated version of the document at this point, in time, that is. Here is what I want you to do. Make sure that you are working inside the Paths palette, make sure that the free-form polygon path is active right here, so that you can see the path outline in the image window. Switch over to your white arrow tool for a moment, if you will. Click somewhere in the path in order to make it active. I am going to switch back to my Full Screen mode by pressing the F key and I am going to zoom out a little bit here.
Now there is a couple of different ways -- let's Shift+Tab away the palettes, so we have a little more room to work. Now there is a couple of different ways to add and delete points from a path. Here is the first thing I would like to do. I would like to go ahead and restore these outlines right here, these edges, these segments that are out here on the paste board; I would like to restore them to perpendicular. So that they are either horizontal or vertical, so that they are just not so sloppy; feeling too sloppy here. I could, of course, drag them around but there is no way for me to just, sort of, snap them. Okay, I did a big Auto Scroll but that didn't help me. There is no way for me to snap them in to alignment with the other points inside of the path. So I will go ahead and Undo that modification. The easiest way to achieve that is to go ahead and redraw that segment.
So I am going to select this point right there. Now I saw that's active; it's solid, so it's selected. I am also going to Shift+Click on this point and I am going to Shift+Click on this point. What that did is it added those anchor points to the selected points. So this guy, this guy, and this guy are all solids and therefore, they are all selected. Now I am going to press the Backspace key or the Delete key on the Mac. When you select an anchor point and then press Backspace or Delete, you remove the neighboring segments as well. Notice that they went away. So you create a hole in the path and we have converted this path from being a closed path outline to an open path.
Now I am going to add points to it. Now if I want to press --By the way, notice now that all of these anchor points or remaining anchor points are active. So if I wanted to remove them as well, I would press Backspace or Delete again. So if you ever want to completely delete a path, then you just press the Backspace key twice in a row and it will go away. Anyway, I don't want that, I want to keep this good stuff right here. Now, to redraw that area, I would go over and grab my Pen tool, then I am going to click on one of these points right there to make it active again. I will show what I mean. Notice right now, if you look closely at the video here, the Pen tool cursor has a little X next to it. That X means it's going to start drawing a new path. So if I start clicking, notice what happens. It starts drawing a new path in here. This is actually a new sub-path because I am still working inside the same path entry here inside the Paths palette but it's not connected to the other path outline.
All right, so I don't want that, so I will go ahead -- actually, it's selected, so let's just go ahead and get rid of it by pressing the Backspace key twice in a row; that would be the Delete key twice in a row on the Mac. Now instead what I want to do is I want to make the path active, I want to make sure one of the anchor points, one of these end points; because it's at the end of the open path, I want to make one of these end points active and I will do that by moving my cursor over the point. Notice then, I get that other little, weird, doo-hickey next to the Pen tool cursor. That shows me that supposed to be a little anchor point with a tiny little edges of the segment next to it and that shows me that I am going to activate this path. So I will click, sure enough, go ahead and activated that anchor point.
Now I will click down here, and I will Shift+Click, and I will Shift+Click, like so. Actually, I, kind of, blew it because I want this segment to be exactly horizontal. Notice, even if I Shift+Click to close the path, it's going to be slightly off because this point was out of alignment. So let's undo that modification. Here is something else you can do. Very useful technique, if you can remember it. You can temporarily access the Arrow tools; whichever Arrow tool you last selected, you can access that Arrow tool on the fly by pressing and holding the Ctrl key or the Command key on the Mac.
So with that key down, you get the Wide Arrow tool in my case and then I am going to click on this anchor point to select it. Now I am going to release the Ctrl or Command and press the Backspace key. Now question becomes, is the path still active? If I move my cursor over here so I can see it, no, it's not because I have got the X, that's telling me it's going to start a new path. So I want to activate things again by clicking on this end point right there. I did get that little point thing, I just can't see it very well because I have got my cursor against the gray background. Now I have got the pen nib without any junk next to it, which means it's adding to the existent path outline. I will Shift+Click up here and I will click down here in order to close the path.
All right, so that's one way to add and subtract points, add and delete points from a path. It's to just go ahead and select them with white Arrow tool, press the Backspace or Delete key to get rid of them, create a big hole in the path, and redraw those points using the Pen tool. You can also, as it turns out, you can also add and delete points inside of a path, that is, points between existing points in the path. Now we are going to see how to do that in the next exercise.
Download Deke's customized keyboard layouts for Channels and Masks from the Exercise Files tab."
- Distorting and shading with a DMap
- Understanding bits and channels
- Creating paths with the Pen tool
- Using blend modes and the Dodge and Burn feature
- Understanding channel mixing
- Using layer masks, clipping masks, and knockouts
- Applying Smart Filters


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Narendra Modi behind Nitin Gadkari row: RSS' MG Vaidya
Top Stories
- Union Cabinet approves scrapping railway budget and merging it with general budget
- Terrorists locked soldiers in cook house, store: Uri attack probe
- Uri attack probe: Army looks at possible insider help, scans route through village on LoC
- US lawmkers introduce Bill to designate Pakistan as state sponsor of terrorism
- Faulty supplies to troops: UN deducts Rs 338 crore from payment to India
BJP also sought to distance itself from Vaidya's remark, saying that no such information has been given to the party.
In his blog, Vaidya has said the "Needle of suspicion in the campaign against BJP president Nitin Gadkari points to Gujarat BJP and Chief Minister Narendra Modi."
He also noted that "Ram Jethmalani had in one breath said he is seeking the resignation of Gadkari and that he also wanted to see Narendra Modi as the Prime Minister in 2014."
While both L K Advani and Gadkari have publicly stated that they don't have Prime Ministerial ambitions, Vaidya, a former spokesman of RSS, said he "hasn't read anywhere that Narendra Modi has denied reports of his ambition to become the Prime Minister".
Vaidya today stood by his remark, saying, "It is my opinion and because Jethmalani has combined two things demanding Gadkari's resignation and making Narendra Modi as PM, I think that the needle of suspicion goes to Gujarat.
"I did not say that, I just said needle of suspicion goes to Modi and that raises suspicion if Jethmalani is entitled to his own point of view, I am also entitled to my point of view and RSS has nothing to do with it."
However, RSS official spokesperson Ram Madhav said the views expressed in the blog by Vaidya are personal and this is "not the official RSS line".
Reacting to Vaidya's remarks, BJP leader M Venkaiah Naidu said, "No such information has been given to us. We are not reacting at all. Let the inquiry be over, let there be no trial outside, it is not fair. I don't know from where this information came. I don't think that this is view of RSS. I can also tell you.
"I am also a RSS swayamsevak, with my own experience of 40 years RSS has not expressed such views, it is not an authorised opinion of RSS. Let me make it very clear. To my knowledge and understanding as a swayamsevak, I also know how RSS functions and as a BJP functionary I don't agree with reported things," Naidu said.
Earlier, BJP Rajya Sabha MP Ram Jethmalani and his son Mahesh had said Gadkari should immediately step down from his post as charges against him with regard to funding of his Purti group were damaging the party.
Jethmalani had claimed to have the support of other senior party leaders like Jaswant Singh, Yashwant Sinha and Shatrughan Sinha.
Talking to reporters at his residence here, Vaidya today said, "There seems to be unrest in the BJP and the lack of solidarity is evident in the party with members openly expressing their resentment".
He said even if there were differences of opinion in the RSS, the Sangh parivar comes out with only one statement or takes one stand in public.
He also said it was too early to talk about Lok Sabha elections and the Prime Ministerial candidate.
"PM candidate and talk of elections will commence only in 2013 when Assembly elections of other states are over and not after the Gujarat Assembly elections are held," he said.
- March of the Maratha: Worryingly, agitation for quota has anti-Dalit colour
- A decade after 'Prakash Singh' judgement, police reform remains undone
- India must craft an appropriate military response to Pakistan
- India has not harnessed its economic success to secure better health for its citizens
- TV channels tossed violent suggestions as casually as a peanut in the mouth
- The Uri challenge: Repair structures to reduce vulnerability, provide deterrence
- India must distinguish between the Pakistani military and its political leadership


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Live coverage of the funeral service for Michael Brown, the unarmed teen who was shot and killed by a Ferguson, Missouri, police officer earlier this month.
The views expressed are not those of this site, this station or its affiliated companies. By posting your comments you agree to accept our terms of use.blog comments powered by Disqus


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NEW YORK — Not bad for his first week in The Bronx.
Yankees right-fielder Carlos Beltran was named the American League Player of the Week, the league said Monday. It was the fourth time he'd won the award in the AL and sixth time overall.
Beltran hit .423 (11-for-26) with four doubles, three homers, six RBI and seven runs scored over seven games over the span.
Among A.L. leaders for the period, the switch-hitting Beltran was first in total bases (24) and slugging percentage (.923), tied for first in hits and doubles, second in batting average and tied for second in homers and runs scored.
Beltran, 36, signed a three-year, $45-million deal with the Yankees in the offseason.
The Yankees started the season with six straight road games.


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Basketball Art for Boston
In the wake of yesterday's tragic events, people all over the country are trying to find ways to help the victims of the Boston Marathon attacks. We can't all be as heroic as the marathoners who crossed the finished line and kept on running directly to hospitals to donate blood or emergency personnel who rushed towards the sound of explosions, not away from them. But everyone has talents and energy that in some small way can make the lives of the those affected better.
With that in mind, we'd love for you to visit fellow Spurs blog Project Spurs and learn more about a group of NBA-minded artists who are doing their part to support the victims of the Boston attacks. Joseph Applegate, Bobby Bernethy, Nicholas Kastner, Michael McGrath Jr., Maddison Bond, Robb Harskamp, Dustin Watson and Jesse Blanchard will be donating all proceeds from their prints for the month of April to Boston relief funds. If you've ever thought about buying a basketball print, now might be the right time to do so.
To learn more about the ways the community of NBA artists and illustrators is doing their part to support Boston, click here.


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Recorded interviews of Tierra Blanca former guests are revealedUPDATED 12:08 AM MDT Oct 15, 2013
Some New Mexico teens report beating and being forced to wear chains while there.Video Transcript
RESIDENTS AT THE TIME, OBTAINED THE DETECTIVE INTERVIEWS, THROUGH A PUBLIC RECORDS REQUEST. KOAT ACTION 7 NEWS REPORTER ANNA VELASQUEZ BEGINS OUR TEAM COVERAGE. WHEN THE SIERRA COUNTY SHERIFF'S OFFICE INTERVIEWED A HANDFUL OF FORMER RESIDENTS... ABOUT THEIR EXPERIENCE ON THE TIERRA BLANCA RANCH .... HANDCUFFS, SHACKLES, AND BEATINGS WERE AMONG THE COMMON THEMES. THIS TEEN CLAIMS HE GOT BEAT UP A LOT, BY SEVERAL BOYS ALL AT ONCE. 1:28 i couldn't get up and i couldn't fight cause i had handcuffs on. and the shackles, they dragged me in shackles and it hurt like :35 ANOTHER FORMER RESIDENT TOLD INVESTIGATORS... STAFF MEMBERS FORCED THEM TO CONDUCT THE BEATINGS. 1:52 just physical beatings, punchings, kickings... usually it was just a punch to the gut or something. you didn't get hit in the face much, most just body damage. :10 BUT IN THIS TEEN'S CASE 1:37 i'll get up, they'll kick me, drop kick me, slam me. :42 HE ALSO RESORTED TO STEALING FOOD BECAUSE HE WAS STARVING, AND WASN'T FED ENOUGH. AS PUNISHMENT, HE CLAIMED A STAFF MEMBER - A FORMER NEW MEXICO STATE POLICE OFFICER - FORCED HIM TO RUN MORE THAN THEY ALREADY HAD TO, AND DO CIRCUIT TRAINING... ALL DAY LONG. BUT WHEN HE PHYSICALLY COULDN'T DO IT ANYMORE... HE CLAIMED THAT MAN BEAT HIM ANOTHER FORMER RESIDENT TOLD INVESTIGATORS... THE NEXT MORNING... THAT TEEN WAS UNRECOGNIZABLE BECAUSE OF THE SWELLING AND BRUISING... AND HIS FACE WAS SWOLLEN BEYOND RECOGNITION. IN MAY... THE STATE POLICE TOOK OVER THE INVESTIGATION. ANNA VELASQUEZ KOAT ACTION 7 NEWS. THERE ARE SOME FORMER RESIDENTS OF THE RANCH, WHO DEFEND ITS
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Jill Johnson and Jeff Suffolk were wed on June 18 at the Bluffs of Bay Harbor, Mich.
The bride is the daughter of Mr. and Mrs. David Johnson of Tecumseh, Mich., and Bonita Springs, Fla.
The bridegroom's parents are Mr. and Mrs. Ronald (Sharon) Suffolk of South Lyon, Mich., formerly of Columbiana. He is the grandson of the late Mr. and Mrs. Al Suffolk, Mr. and Mrs. Richard Ferrall and Donald Mackall.
Article Photos
The bride's brother, Mark Johnson, officiated.
Jennifer Suffolk Chappell, the bridegroom's sister, was matron of honor.
Jim Jackson served as best man.
Allison Chappell, the bridegroom's niece, was the flower girl.
Collin and Gray Johnson, the bride's nephews of the bride, were junior groomsmen.
The bride is a corporate recruiter for Bright Horizons, Bloomfield, Colo. The bridegroom is the owner of Human Movement LLC, Boulder, Colo. Both are graduates of Western Michigan University.
The couple resides in Lafayette, Colo.
A reception for approximately 125 guests was held immediately after the ceremony at Bay Harbor.


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Cardinals running back Beanie Wells said Monday he fully expects to be playing for another team next season and said he will be using Sunday's season finale against the San Francisco 49ers to "audition for a job somewhere else."
"That's my mind-set," Wells said, a day after he was benched following a fumble that was recovered and returned for a touchdown in Arizona's 28-13 loss to the Chicago Bears. "I'm just going to go out there and put my best foot forward for all the 31 other teams that's watching."
Asked to confirm if he felt his days were numbered with the Cardinals, Wells replied:
"Oh, without a doubt. It's inevitable."
Wells, the team's first-round pick out of Ohio State in 2009, has had an injury-plagued career in his first four NFL seasons. He's battled knee problems and spent much of this season on recallable injured reserve because of a knee problem and a turf-toe injury.
"You never expect things to unfold the way they do, but it's a part of life and you have to roll with the punches and adjust to them as they come," Wells said.
Wells said he's seen a pattern since joining the Cardinals that tells him it's probably for the best that he moves on. He is still under contract for next season but sounded Monday as if he will be traded or released at some point in the off-season.
He said he hasn't had any "hard discussions" with the Cardinals about his future, but added, "This is a performance-based business, and I don't know if I've done things up to our organization's standards here. Maybe it's a discussion that we'll have later on, but who knows?"
As for his first-quarter fumble against the Bears and then being banished to the sideline, Wells said it was his fault he lost the ball when he slipped and fell to the ground. But he said he should have been given a chance to redeem himself.
"I didn't agree with it at all," he said of being benched.
Coach Ken Whisenhunt said Monday that he hasn't lost confidence in Wells but stressed that turnovers cannot be tolerated, especially with the way the Cardinals' offense has struggled.
"If you have the ball, that's your responsibility," Whisenhunt said. "You can't turn it over. I don't care who you are, I don't care what position you play. In the NFL, if you turn the ball over you're not going to play. That's the way it goes, and that's been through history. There have been guys that have been good players that couldn't hold onto the football, and turnovers are something that are hard to overcome and you can't do that."
Wells said he doesn't think a conversation with Whisenhunt will change anything.
"I've got one more game, and hell," he said, "then let everything else go away and where they go from there."
2013 opponents set
The Cardinals' opponents for next season are set now that all last-place teams within the NFC are known.
Arizona will have home games against the Colts, Texans, Jaguars, Panthers and Lions, in addition to visits by NFC West rivals San Francisco, Seattle and St. Louis. In addition to playing those three division opponents on the road, the Cardinals will also travel to New Orleans, Philadelphia, Tampa Bay and Tennessee.
Housler likely out
Second-year tight end Rob Housler isn't expected to play Sunday against the 49ers after suffering a shoulder injury in the second half against the Bears.
"I would say it's not a very good chance that he'll play this week, which is disappointing because he's one of the younger guys that have really developed this year and done a lot of things," Whisenhunt said.


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A Hard Road to Freedom Happy New Year, Detroit! 2013 has finally arrived, and 2012 is part of our recent past. Although we have much to be thankful for, it truly has been a hard road to freedom. Since the reelection of President Barack Obama, the great state of Michigan and the city of Detroit have been overtaken by political turmoil and chaos.
Both the state of Michigan and this country seem to be faltering amid intense divisiveness. President Obama, the U.S. Senate and the U.S. House averted falling over the fiscal cliff by compromising America's financial security on the first day of the New Year, but this choice is truly the hard road.
The city of Detroit faces insurmountable debt and is nearing financial collapse, while looming over so many voiceless taxpayers is an emergency financial manager and possible Chapter 9 bankruptcy. No one is free without eliminating the country's debt.
Despite all the successes and failures of 2012, we must remember that history replays itself. It has been a tough year for many, but things are about to get tougher with the critical situations we will be facing in 2013. We have an opportunity to fundamentally change Detroit, but let's not change it for someone else's benefit or special interests.
"We, the people of Detroit, note that the state economy can be built upon the principle that one place can be exploited, even destroyed, for the sake of another place."
This situation reminds us of the slave trade, in which many Africans lost their freedom. Remember, in the United States, a wilderness of greed created an economic windfall for the elite and this in turn created the American slavery and apartheid system, which we still see remnants off today. We are reminded that as we celebrate the 150-‐year anniversary of the Emancipation Proclamation signed by President Abraham Lincoln, Jim Crow laws ruled, until voiceless men and women became sick and tired of sitting at the back of the buses. Soon, civil rights activists needed affirmative action to try to right the wrongs of those who view injustices as justice.
"President Abraham Lincoln issued the Emancipation Proclamation on Jan. 1, 1863, as the nation approached its third year of bloody civil war. The proclamation declared "that all persons held as slaves" within the rebellious states "shall be then, thenceforward, and forever free."
Although today, tomorrow, and the coming months will be difficult, we have a voice. We must neither forget the past nor hold on to it, and we cannot give up, because those who wish to oppress us relish the thought. We must remain vigilant and hopeful; we must stand strong, which in 2013 justifies the continued hard path to freedom. If you are not willing to die for something, then what else is there to live for? The fight for our freedom continues, even 150 years later.


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The Planet Eclipse HDE Kitbag is slightly longer than the Planet Eclipse Classic Kitbag making it perfect for larger loads and is designed to better accommodate larger paintball and airsoft equipment. It fits perfectly into the HDE product range complete with loadout webbing on the side pockets and on the inside lid so you can attach your HDE accessories, pouches, grenades etc. The external patch zones also match the HDE Jersey specifications so you can make your own team patches and swap them freely between products.
The large external side pockets are great when ease of access is required and the bag comes with a handy fold-away water resistant ground sheet so you can work with your gear on the floor or detach it from the velcro to work anywhere even in muddy/damp conditions.
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Technical information
Begin of tour: Grengiols
End of tour: Binn
Technical requirements: easy
Physical fitness: medium difficulty
Distance: 17 km
Total altitude meters: 1003 m
Biking time: 5:30 (hours, minutes)
Elevation start of tour: 995 m
Elevation end of tour: 1400 m
Culmination point: 1699 m
Season: -
Gastronomy: Restaurants in Grengiols, Binn (Historical Hotel Ofenhorn"), Fäld
Overnight: Hotels in Binn (historical Hotel "Ofenhorn"), Fäld.
Various: The mineral mine in Lengenbach, Geology Trail Imfeld - Lengenbach. Roman Bridge across the Binna River
Access starting point: By train from Brig of Göschenen (KB 610)
Access point of arrival: Binn
Grengiols - Ried - Blatt - Steinmatten - Ze-Binne - Binn - Giesse - Mineraliengrube - Fäld - Binn
The hike from Greniols along the Binn River to the mineral mine of Lengenbach in the uppermost section of the Binn Valley opens up to spectacular vistas, a nature paradise that let's visitors' hearts beat faster.
Tour Overview
3D hiking map Download GPX coordinates Download KMZ (GoogleEarth)
The careful planning of a tour will ensure that you also derive the maximum pleasure and enjoyment from it. Please take the time to contact the local information centre and enquire about route and weather conditions before setting off. Your intended trail may be fully or partially closed, depending on the time of year and weather conditions.


text: Nestled right in the heart of The Garden of England, Maidstone is the perfect place for exploring everything that this beautiful county has to offer. Whether you're looking for buzzing nightlife and a vibrant shopping location or a peaceful, country escape – you''ll find both right on Maidstone's doorstep. Hiring a car in Maidstone means you can whizz around town with ease, as well as having the freedom to go further afield. Our branch is conveniently situated just off the M2 at The Tudor Park Hotel, so you can rent a car and make the most of your trip to Kent.


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The coke machine in college takes 50 pence pieces. It also takes a certain foreign coin of traditional design. Coins inserted into the machine slide down a chute into the machine and a drink is duly released. How many more revolutions does the foreign coin make over the 50 pence piece going down the chute? N.B. A 50 pence piece is a 7 sided polygon ABCDEFG with rounded edges, obtained by
replacing AB with arc centred at E and radius EA; replacing BC with arc centred at F radius FB ...etc..
A white cross is placed symmetrically in a red disc with the central square of side length sqrt 2 and the arms of the cross of length 1 unit. What is the area of the disc still showing?
A security camera, taking pictures each half a second, films a
cyclist going by. In the film, the cyclist appears to go forward
while the wheels appear to go backwards. Why?


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Steelers-Giants pregame stretch
November 2, 2012 - Ray Eckenrode
Pittsburgh Steelers (4-3) vs. New York Giants (6-2)
Sunday, 4:25 p.m., CBS
Weather – or not?: Partly cloudy, 50. The game time weather is not the issue here, it's whether an NFL game should even be played in New Jersey considering the devastation most places within 100 miles of the stadium suffered in Hurricane Sandy. But in our world today, if there's one thing that supersedes a storm of biblical proportions, it's an NFL home game.
Information from www.weather.com
Announcers: Jim Nantz and Phil Simms
Annoyance factor: The best we can say about this is that it will be interesting to see how Nantz's anti-Steelers bias plays out in an NFC game. Simms has slipped badly as an analyst over the past two years and the best we can say about this is that it provides lots of fodder for Twitter and the blog. Also, it looks like we'll be getting Denver-Cincinnati in the early game rather than the much more sensible Cleveland-Baltimore matchup. Thank God for the NFL Red Zone. (Notice how we used a capital letter to indicate that we want to thank the real God for red zone, it's that important to us.)
Information from www.the506.com
Referee: Bill Leavy
Competence factor: Hopefully, the replacement ref debacco in Seattle earlier this year will finally allow Leavy to stop beating himself up over the blown calls in Super Bowl XL that went against the Seahawks (not in the "that evens it out" sense, because it doesn't, but in the "mistakes happen and they didn't really decided that game" sense). The last few Steelers games with this crew have been uneventful and hopefully that trend continues Sunday.
Information from www.football-refs.com
The line: Giants -3.5
Smarts say: This opened as -3.5 and very quickly dropped to -3, meaning a lot of smarts jumped on the Steelers and that "extra" half point. It then floated back to the original line, meaning more casual betters slightly favored New York. An over/under of 47.5 means something in the neighborhood of 26-23 Giants (where those early-betting smarts win) or 27-23 Giants (where they'd lose).
Information from www.sportsbook.ag
Key matchup: Steelers offensive line vs. Giants front four
Because: The improvements made by the Pittsburgh OL in the past two weeks is the best reason to hope the Steelers can improve to legitimate contenders by year's end. But this will be a much sterner test for that group than anything they've seen recently. With Justin Tuck, Jason Pierre-Paul and Osi Umenyiora, New York can pressure quarterbacks without blitzing, allowing them to still play coverage behind. That means there are very few "easy" checkdowns on this defense, which means Ben Roethlisberger will need time to get through his progressions in order for the Steelers offensive to be effective with those long, time-consuming drives that have become a staple this year. Justin Tuck going against Mike Adams is the most concerning matchup because if Adams struggles, it will require Heath Miller to spend more time blocking than receiving and he's obviously become the offense's biggest weapon this year under Todd Haley.
Quick hits:
+ Under the heading of "Lies, Damn Lies and Statistics," the Steelers defense is No. 2 in the NFL (by 0.3 yards per game to the 49ers) and No. 1 against the pass. Obviously, no one in their right might (and certainly not Mike Tomlin as evidenced by the 54-yard FG attempt a few weeks ago against the Titans) wants Pittsburgh's defense on the field right now with the game on the line. As we told Cory Giger on his radio show this week, it's an indication that WHEN you do something in the the NFL is much more important than WHAT you do. Now playing devil's advocate, let's take Ike Taylor's position that those stats are a legit indicator. Then how do you have the No. 2 defense and THAT offense (which ranks 10th, btw) and still only sport a 4-3 record?
+ There's one problem with the theory that the Steelers will be loaded at running back when Rashard Mendenhall and Isaac Redman return from injuries: Reality. In theory, three are better than one, but in practice, both Jonathan Dwyer and Mendenhall have shown they're the kind of back that needs to get ALL 18 carries in a game to be truly effective. Only Redman has shown he can be effective (actually more effective) as a reserve/situational runner. What the Steelers really have a running back is depth.
+ History has shown the upcoming five-game stretch (November and first week of December) is critical to the Steelers success. Dating back to 2008, they've gone 4-1 in this stretch four times, culminating in two Super Bowl appearances. They went 1-4 in 2009, when they finished 9-7. Assuming Pittsburgh can handle Kansas City and Cleveland, that means they'll need to beat the Giants and split with the Ravens, or, should they lose this Sunday, sweep the Ravens. That's a tall order either way.
+ You can bet the Giants receivers won't drop seven passes this week.
The pick: Every rational aspect of this game (including the Steelers Sandy-driven travel hassles) screams GIANTS! So we're going with Pittsburgh. We're expecting Ben Roethlisberger's best game of the year. We're expecting Antonio Brown to redeem himself for his foolish hot dogging last week. And we're expecting Will Allen and David Paulson to make big plays. Hey, if you're going to make a crazy pick, make it real crazy … Steelers 27-21.
Last week: We were right on the mark about the Steelers playing well and the Redskins struggling, moving us up to a mirror image of Pittsburgh's record at 4-3.


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Mavericks Targeting Free Agent Point Guards
Most of the point guards that the Mavericks are believed to be interested in ? Monta Ellis, Mo Williams, Jarrett Jack, Chauncey Billups, Jose Calderon ? remain on the market.
The Mavericks are working behind the scenes talking to numerous agents regarding potential acquisitions. But until Howard makes his choice, all talk is premature.
via Eddie Sefko of The Dallas Morning News


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Amazing. There is no other way to describe the return of St. Louis Cardinals ace Chris Carpenter to the mound just two months after undergoing major surgery. Carpenter is making his season debut this afternoon at Wrigley Field as the Cardinals visit the Chicago Cubs. The last time Carpenter pitched in the majors was Game 7 of the 2011 World Series. Friday's game might not have the same competitive implications, but the significance of Carpenter taking the mound is perhaps greater.
Bell: Carpenter Makes Surprising Return to Action
From ESPN.com
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Saturday, November 10
1 Month
Our sweet baby turned a month old today. I can't believe how fast the month flew by. He is a pretty mellow baby. He has reflux but doesn't show it at all. The only way we knew he had it was when he stopped breathing. He choked on what is believed to be spit up that came up through his nose. This happen at a week old. We rushed to Vandy where they monitored him to make sure it was nothing serious or happened again. He does spit up but nothing compaired to his big brothers. Sometimes it does come through his nose. He is very spoiled because he is never out of our sight now. He is a good baby. He has noticed his mobile and is more alert lately. WE LOVE OUR SWEET PEA!!!
1 month
Weight: 7lbs
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Man sought in robbery attempt at Olathe Subway
Would-be robber flees after struggle with clerk
Published 1:57 PM CDT Apr 29, 2013
Olathe police said investigators are looking for a man who struggled with a clerk while trying to rob a Subway restaurant late Saturday.
Police said a man in a black hoodie came into the store at 11100 S. Lone Elm Road at about 9:30 p.m. and demanded money out of the register. The clerk and the man got involved in a struggle and the would-be robber ran out of the restaurant empty-handed.
Olathe police asked anyone with information in the case to call the Crime Stoppers TIPS Hotline at 816-474-8477.
Copyright 2013 by KMBC.com All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Documentary honoring AT hiker Emma Gatewood heads for production
I first heard the name of Emma Gatewood as a passing reference in a script I was given when I was doing a voice-over project for the Buckeye Trail Association. The 50th Anniversary script mentioned that one of their founders, Emma Gatewood, was the first woman to solo thru-hike the Appalachian Trail (AT) at the age of 67 (today is her 126th birthday). I called the person I was working with on that project and said, "Never mind the Buckeye Trail, who's this Grandma Gatewood person?" and that started me on the Trail To Grandma Gatewood.3 comments


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Erosion from high winds and high tides last weekend punished dunes on Folly Beach, Sullivans Island and Isle of Palms.
Tim Goodwin, Folly Beach mayor, said the damage was worse than from passing Hurricane Sandy last month.
The worst part, though, going into the winter season when noreaster storms tend to wreak havoc, might be that the tides werent that high, only a foot or so above normal. But the winds blew near 30 mph.
Read more in upcoming editions of The Post and Courier.


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oh, crap. This is on my TODO list now, thanks for the heads up.
You're half correct. it doesn't run off an unpatched retail bios - you need to be able to run unsigned code. Most people have a hacked bios in order to do this, but I believe nkpatcher patches the retail bios on the fly, making it a legal distribution? (someone correct me if I'm wrong.)
However, it is a completely legal binary.
I forgot to mention this in the first post, but a million thanks go out to everyone working on the openXDK - this program is just a demo of it's (constantly expanding) capabilities. OpenXDK Homepage.
edit: People who are having problems with getting input to work, please keep reporting the scenarios. Thanks!
Edited by d0wnlab, 30 June 2005 - 03:49 AM.


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Kids will be kids. And there's nothing you can do about that. But that doesn't mean you have to suffer through play dates sober.
The Three-Martini Play Date
Heirloom Tomatoes
Tempting as it is to subsist on tomatoes alone this time of year, eventually the need for something—or someone—else rings true.
Never Cook Naked: Pesky Pin Bones, Rude Roomies, Soapy Challah
Our very wise, very clothed columnists tackle your most recent cooking questions with wit and wonder.
Food Souvenirs
When it comes to travel, you can take it with you. But then what? Cristin Nelson dishes on the dirty little secret behind food souvenirs.
When Life Hands You Tornadoes, Make Blueberry Muffins
Being a mom and meteorologist don't always go hand in hand. But as long as there are muffins made from scratch, who cares?
- Quick Glance
- 11
Coke and Peanuts
Carol Penn-Romine takes us back to her childhood and a secular southern sacrament that's still solemnly revered.
Julia Child: What I Have Learned
The American doyenne of French cooking expounds upon what she learned during a lifetime of cooking—and thinking—at the stove.
One Anxiety Attack, Hold the Fries
For some, a trip to a fast-food condiment counter is no whoop. For author Daniel Smith, it's nothing short of a panic attack.
The Best Summer of My Life
Israeli writer Meir Shalev recounts with wry humor and great love the long and zany summer days on his grandparents' farm in Nahalal.
Never Cook Naked: Nonstick Grilling, "Reusable" Bamboo, Meat Safety
Savvy, simple, and (mostly) commensense advice on grilling without sticking, the meaning of "reusable disposable," and safe barbecuing.
The Essential Bistro
An unabashedly biased look at what makes the bistro such an essential–and quintessential–social sanctuary.
Urban Grilling
When city dwellers attempt to recreate a backyard barbecue in a public park, is it truly urban grilling? Or is it barbecue blasphemy?
Eat Local. Kill a Weed.
The incredible edible…weed? Faith Durand recounts how her freshman gardening season hazed her with leafy surprises.
Never Cook Naked: Host(ess) Gifts, New Mexican Chiles, Wax (?) Paper
Our cooking columnists answer your questions on gift etiquette, how to get your hands on hatch chiles, and paper properties.


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A Texas principal is under fire after allowing a controversial presentation on Islam at her public school.
Friendswood Junior High principal Robin Lowe let the Council on American Islamic Relations speak on Islam May 22.
They talked to nearly 900 students about the religion without the approval of the administration or parents.
Parents packed into a recent school board meeting to discuss the event.
Some support the principal, but others are very concerned that a group like CAIR could make such a presentation without the school's permission.
"She is not being hung out to dry as some have suggested she has proven herself to be a first class educator and she does not deserve to be vilified," Friendswood Superintendent Trish Hanks said. "I am deeply concerned that an organization like CAIR was allowed access to our school."
Principal Lowe has asked to be reassigned to an administrative position.
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Payne, Spencer Ca,b; Chen, Philip Ga; Borish, Larryb
Purpose of review: Patients with seasonal and/or persistent symptoms consistent with rhinitis but negative systemic testing for atopy can be diagnostically challenging. It has been postulated that such idiopathic or nonallergic rhinitis may be due to localized class switching and production of IgE in the nasal mucosa, a process which has been termed entopy by some authors. This review analyzes the available data to describe the current understanding of this process as it relates to nonallergic rhinitis.
Recent findings: Recent findings have demonstrated local IgE production in the nasal mucosa of patients who are otherwise negative on skin prick, intradermal, or serum testing for atopy. Comparable studies on nonatopic asthmatics have demonstrated evidence of local IgE class switching in lung respiratory mucosa. However, local class switching has only been unambiguously demonstrated in rhinitis patients when atopy is otherwise confirmed by routine testing.
Summary: There is significant evidence to indicate that local class switching in nonallergic rhinitis is possible; however, this has not been definitively proven. The question is raised as to whether local class switching can be demonstrated in nonallergic rhinitis and whether that class switching can be determined to be a specific affinity matured response. If present, a local IgE-mediated process is likely to define a cohort of nonallergic rhinitis more likely to respond to allergy-targeted therapies.
© 2011 Lippincott Williams & Wilkins, Inc.
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Ferrari gives the 599 GTB Fiorano a spit and polish with its HGTE package
As it nears the end of its product cycle, Ferrari is giving the 599 GTB Fiorano an extra lease on life with a 'Handling Gran Turismo Evoluzione' (HGTE) package. The package hones the 599's performance with the inclusion of modified suspension with stiffer springs, rear anti-roll bar and new calibration settings for the magnetorheological (a type of smart fluid that becomes a viscoelastic solid when subjected to a magnetic field) shock absorbers.
The ride height has also been adjusted to lower the car's center of gravity, which combines with specially optimized tires featuring a compound that offers better grip and improved handling. The car's electronics have also been modified to ensure even prompter response to driver commands. Thanks to the F1 Supershift gearbox, each of the 599's six gears can be selected at lightning speed, while a new engine software strategy has improved accelerator response.
On the exterior, Ferrari has added 20" split-rim wheels with special diamond-cut and matte silver finish, while the rear diffuser has been finished in matte black to highlight the chromed tail pipes. The exhaust silencer has also been modified, producing an even more thrilling sound under hard usage while still delivering just the right comfort levels at cruising speed.
Inside, the seats are trimmed in a new two-tone combination of leather with black Alcantara inserts, and the seat backs are trimmed entirely in carbon-fibre. Embroidered in contrast stitching on the headrest are a Prancing Horse and the words "Handling GTE".
Powered by a 6.0 litre 456 kW V12 engine, the Ferrari 599 HGTE boasts 608 Nm of torque and will thunder to 100 km/h in just 3.7 seconds, past 200 km/h in 11.0 seconds and on to a top speed of 330 km/h. The maximum engine speed of 8400 rpm is 900 rpm higher than the 575M Maranello and, according to Ferrari, is comparable only to that of the Enzo for a car of this type.
Anyone who had already slapped down their hard earned for the 599 will be relieved to know that, as well as being an option on new 599s, Ferrari has also made the HGTE package available as a dealer-installable kit on existing 599s. Price is dependent on the specific kits required and the model year of the car.