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Strukturbasierte Analyse calciumcoordinierender Proteine an der Synapse
Autor :
Carsten Reißner
Herkunft :
OvGU Magdeburg, Fakultät für Naturwissenschaften
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The neuronal chemical synapse is an structurally and functionally highly complex interface of nerve cells. The molecular constitution and the manifold interactions of synaptic proteins is to great extent still unknown. Several functionally important synaptic processes do require calcium. The first part of this work characterizes the largest family of calcium-binding proteins, the EF Hand proteins. This family has been found to express a wide spectrum of conformations which make it difficult to functionally classify new proteins. To address this challenge a method has been developed to model new protein sequences into all possible conformers. That method of building conformational space models allowed the correct prediction of the myristoyl switch of the neuronal calcium sensor (NCS) protein VILIP and a new conformational transition state of NCS proteins. Additionally, the binding sites of EF Hand proteins of new interaction partners was found as e.g. the binding site of caldendrin on jacob. In the second part that method is used to efficiently design site directed mutations and subsequently analyze the transsynaptic neurexin/neuroligin complex. This complex seemed to play a unique role in synaptogenesis and maturation of the synaptic contact. Neurexins are cell surface proteins which bind to neuroligins forming a calcium dependent complex. This heterophilic complex is required for synaptic function and defects in genes of both proteins correlate with autism. The aim of this work was to use site directed mutagenesis to identify essential residues at the binding interface. Several model complex structures have been generated to facilitate the design mutations that completely block complex formation. It was found that EF hand motifs in neuroligin are degenerated and not required to bind to neurexin as suggested elsewhere. For the first time, calcium-45 binding to neurexin was detected. Performing multiple steps of modeling, mutagenesis and binding studies the binding site for neuroligin could be sharply delineated. Neuroligin binds to hydrophobic residues which surround the calcium-binding pocket and give the sixth LNS domain from alpha-neurexin and the LNS from beta-neurexin a unique property. Point mutations that changed electrostatic and shape properties leave calcium-coordination intact but completely inhibited neuroligin binding, whereas alternative splicing in alpha- and beta-neurexins and in neuroligins had a weaker effect on complex formation. In neuroligins, the contact area appears less distinct because exchange of a more distant aspartate completely abolished binding to neurexin but many mutations of predicted interface residues had no effect on binding. Calculating binding energies of wild-type and mutated complexes using the coordinates from recently determined beta-neurexin/neuroligin 1 crystal structures confirmed that the contact area in neurexin is rigid and invariable. Additional binding and comparative structural studies revealed that neurexin binds to all neuroligin isoforms using the same hydrophobic contact area. In contrast, neuroligin 2 does not fit into the complex structures of the other isoforms and may have an alternate binding area for neurexins.
Schlagwörter :
Neurexin, Neuroligin, EF-hand, VILIP, Caldendrin, Jacob,Structure modeling, Structure prediction, Alternative splicing, splice-c
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text:
Video: LA bus riders protest transportation cuts
Bus riders gathered on a busy street in Los Angeles, California, recently as part of a national day of action to stop bus service cuts and fare increases.
Black Caucus message: Pass jobs programs now!
The Congressional Black Caucus kicked off its 41st Legislative Conference with resounding calls for quick passage of President Obama's $450 billion jobs program and jobs bills introduced by CBC members.
Health Equity Summit highlights progress, problems
The Affordable Care Act has opened the way for great progress toward overcoming racial, ethnic, gender and geographic health disparities. But much hard work lies ahead to make sure its promise is realized at the federal, state and community level.
Labor launches new drive to back Obama on deficit
The AFL-CIO has launched an on-line letter campaign that will enable millions to directly write their lawmakers in support of the president's deficit reduction and job creation plans.
Congressional Progressive Caucus presents jobs plan
Following up on speak-outs it organized around the country during the summer the Congressional Progressive Caucus Sept. 13 unveiled a far-reaching Rebuild the American Dream Framework, focusing on six areas for immediate and long-term job creation.
Trumka: New GOP bill would gut workers' rights
Republicans are backing a new bill they introduced after the NLRB filed a complaint against Boeing, which the board says retaliated against workers for exercising their rights.
Joint session of Congress to hear the president on jobs
President Obama and House Speaker John Boehner agreed Wednesday night to a joint session of Congress, ending yet another GOP attempt to embarrass the president.

subset: commoncrawl


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Cochranton man wanted in stabbing
COCHRANTON -- State police at Meadville are looking for a 58-year-old man wanted in connection to a stabbing Friday evening.
Police said Donald N. Bartholomew, of Cochranton, got into a fight with Dalton Levi J. Shetler, 22, also of Cochranton, at about 7 p.m. Friday and stabbed him before fleeing the scene. Vernon Township District Judge Michael Rossi issued a warrant for Bartholomew's arrest on charges of aggravated assault, terroristic threats, simple assault and recklessly endangering a person.
Police described Shetler's injuries as not life-threatening.
Anyone with information on Bartholomew's whereabouts is asked to contact the state police Meadville barracks at (814) 336-6911.


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More iHome Black Friday Deals, save up to 50%
23 November 2012 1,255 views 4 Comments
What does a great deal on an iHome audio peripheral sound like? Try the iDM71, an innovative stereo speaker system integrated into a durable iPad case, on for size — it's marked down 50 percent. Step inside for more iHome Black Friday deals!
Earlier this week, the Fairer Platform introduced you to more than a dozen great iHome Black Friday deals, including 40 percent off the iP97 for iPhone and iA90 for iPad and iPhone.
There is, however, more. SDI Technologies has knocked down iDM71, iP37BB and RT62 prices by 50 percent (image above). Just click through for More iHome Black Friday Deals, and be sure to use Coupon Code: BLACKFRIDAY at checkout.
Related posts:
— Black Friday Mac: New MacBook Air, $699
— Black Friday Mac: Get Roxio Toast for $69.99
— Refurbished MacBook Pro: Return of the $929 MBP
— Borderlands 2 for Mac now shipping
— Holiday Mac Bundle: TechTool Pro, RipIt, Freeway Pro, more for $49.99


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Expanding Use of NGS Has Largely...
NSCLC is "Major Battlefield" as Merck,...
LC-MS Gains Favor Due To the...
Wall Street Decline Takes Its Toll...
Measurement of algal growth parameters such as cell size, cell number, and growth rate is important for confirming optimal growth conditions and culture health. One of the best ways to simultaneously assess algal culture health is to take a series of cell size and number measurements during their growth cycle. The simplest method to do this is to use the Coulter Principle.
Other methods such as combining spectrophotometry (light scattering or absorbance assays) with manual hemocytometer counts are slow, cumbersome, and difficult to perform quickly, especially in the field. Until recently, simultaneously measuring cell size and number with the Coulter Principle required expensive stationary equipment. These systems were inaccessible for many laboratories and not amenable for field measurements.
Many algal species do not undergo binary fission, especially the model algal Chlamydomonas reinhardtii, which instead undergoes multiple fission, where cell growth and division are uncoupled. Moreover, being photosynthetic, many algal species, including Chlamydomonas, synchronize their cell cycles to the availability of light and divide in the dark. Consequently, when growing, Chlamydomonas cell numbers remains unchanged while cell size increases as much as 10-fold in a single day (Figure 3A).
Measurement of the growth of Chlamydomonas during light cycles is best performed with the Coulter method. The Moxi Z is being applied as an inexpensive portable instrument for measuring cell number and sizes in the laboratory at Kansas State University.
For example, in Figure 3A, a synchronous culture of Chlamydomonas was sampled just as growth had initiated and then six hours later of a total, 14 hour, growth cycle. While the number of cells in the synchronous sample has not changed (determined by the Moxi Z as 3.51e5 cells/mL), the volume of the cells has changed from ~50 µm3 to ~320 µm3, a fivefold increase in cell size in six hours.
In addition to being a valuable tool for measuring Chlamydomonas growth rates, the Moxi Z can also be used for determining physiological differences between species. For example the author's lab also uses Chlamydomonas and a closely related colonial multicellular alga, Gonium pectorale, as a model system for multicellular evolution.
Chlamydomonas is a unicellular strain, while Gonium species are colonies of Chlamydomonas-like cells that remain attached through cytoplasmic bridges (see micrograph insets). The lab uses a variety of Gonium strains in the course of research. Using the Moxi Z, it is straightforward to determine if a particular culture is in fact Gonium.
The Moxi Z is also ideal for characterizing Gonium colony size and cells per colony. For example, Figure 3B shows the corresponding size profiles on the Moxi Z (Figure 3B blue versus green). From these data, the Gonium strain is ~850 µm3, suggesting it is composed of 8 cells of ~110 µm3, a fact confirmed by microscopy.
The Moxi Z mini automated cell counter provides a valuable three-parameter cell assay (count, sizing, health) in just 8–15 seconds. Leveraging the single-cell resolution of the Coulter Principle, this information is provided with a degree of precision and accuracy rivaled only by higher-cost counting systems. However, the Moxi Z achieves this performance with enhanced usability, increased functionality, and a maintenance-free operation.
Brad Olson is assistant professor, division of biology at Kansas State University, and Greg Dittami ([email protected]) is senior research and development scientist, and H. E. Ayliffe is founder and CEO at Orflo Technologies.
Brad Olson is assistant professor, division of biology at Kansas State University, and Greg Dittami ([email protected]) is senior research and development scientist, and H. E. Ayliffe is founder and CEO at Orflo Technologies.
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FS Home Collections Deer Cushion
Invest in a luxury cushion from premium designer brand FS Home Collections. Featuring a majestic, embroidered image of a deer on the front and a soft, luxurious velvet back, this designer FS Home Collection cushion is what every contemporary home needs, or why not purchase this as a gift for a special occasion
- H 45.5 cm x W 45.5cm
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Pete Billmann
Lecturer, Jazz Guitar
BA UW-Madison, Jazz Studies
Pete Billmann has been a freelance guitarist in the Milwaukee area for over 20 years. He earned his bachelor's degree in Jazz Studies from the University of Wisconsin-Madison, with additional study at the Wisconsin Conservatory of Music, and has studied with several renowned jazz artists including Jim Hall, Richard Davis, Gene Bertoncini, and fellow UW-Milwaukee faculty member Don Linke. In addition to his background in jazz, Mr. Billmann also studied classical guitar with acclaimed guitarists Benjamin Verdery and Javier Calderon. Pete has also worked extensively as a transcriptionist and arranger for Hal Leonard Publishing, and his work has been featured in dozens of guitar magazines and publications worldwide. As a guitar instructor, he has served on the faculty at the Wisconsin Conservatory of Music as well as being a guest clinician at schools and colleges throughout Wisconsin, and has also taught privately for over 25 years. Pete Billmann joined the UW-Milwaukee guitar department in 2007.


text:
Created in this Craftsy class
Stitch & Slash taught by Carol Ann Waugh
Popular instructor Carol Ann Waugh returns to Craftsy for more fiber fun. Get your seam ripper ready to destroy in the name of creation.
Other projects made as part of this class:
QuiltingBoxed in!
Quiltingmy quilt runneth over
Offer some kudos...
Join the conversation...
Ask a question...
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This looks like a fun, free form project. Nice job.
08/08/2013 Flag
Very interesting design! I might also call it "Connecting the Dots"!
08/08/2013 Flag


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Hit a jumper! Make that 17-footer! You're wide open! More than a few of us have been frustrated by seeing an All-Star talent player not being able to make a simple jumper or the wide open three. Many like Antoine Walker were willing to throw up shots and shoot a very low percentage. Others are just unwilling to put shots up just due to the lack of improvement in their outside game.
That is what is at focus in this article—ten players who are on the rise or have been above solid players in the league who can drastically or decently improve their games with a better shot. I am thinking in terms of a jumper, but a three-pointer could be relevant as well.
The ability to make them a go to guy with the game on the line is also a main factor. Everyone of these players have been secondary with the exception of one (maybe two) depending on the opinion of each person. The improvement I'm looking for here could make the talented underachiever an All-Star and an All-Star a Superstar.
Here's the 10 that most need to improve to reach the next level.


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Winter-Greens Pie with Mushrooms, Caramelized Shallots & Feta
Here's a meatless main dish that's hearty enough for the coldest winter day. Winter greens such as kale, chard, and spinach (your choice) are packed with fiber and feel-good vitamins, yet taste rich and comforting when paired with mushrooms, sweet caramelized shallots, creamy feta, and toasted walnuts.
Total Time: 1 hour, 10 minutes
Hands-On Time: 35 minutes
Yield: 6 servings
- 8 sheets phyllo dough
- 4 tablespoons olive oil, divided
- 6 large shallots, peeled and thinly sliced
- 3/4 teaspoon table salt, divided
- 1/4 teaspoon granulated sugar
- 8 ounces sliced white button mushrooms
- 2 large bunches Swiss chard, kale, or spinach, thick ribs removed, sliced crosswise into 1/2-inch-wide ribbons (about 10 cups packed leaves)
- Pinch ground nutmeg
- 4 tablespoons salted butter, divided
- 5 ounces feta cheese, crumbled
- 1/4 cup finely chopped walnuts
InstructionsCarefully lay defrosted sheets of phyllo on waxed paper or parchment on a counter; cover with a damp towel. Set aside.
Warm 2 tablespoons oil in a large skillet over medium-high heat; then add shallots and 1/4 teaspoon salt, and cover. Cook 3 minutes to soften shallots; then remove cover, add sugar, and reduce heat to medium-low. Cook, stirring occasionally, until shallots are golden, about 20 minutes.
Meanwhile, pour remaining 2 tablespoons oil into a medium-size skillet over medium-high heat. Add mushrooms and 1/4 teaspoon salt. Cook, stirring often, until nicely browned, 10 to 12 minutes. Set aside.
Preheat oven to 375° and set rack to center position. Add greens to skillet with shallots. Increase heat to medium-high and cover. Let cook 2 minutes to soften; then use tongs to turn greens over. Add nutmeg and remaining 1/4 teaspoon salt; cook, stirring, until loose liquid is mostly evaporated, 8 to 10 minutes. Add 1 tablespoon butter and stir.
Melt remaining 3 tablespoons butter. Brush a bit of melted butter on the bottom and sides of a bread pan; then lay first sheet of phyllo dough into the pan so that it covers the bottom and then drapes up and over the right side by several inches. (The left side should be uncovered.) Brush gently with melted butter. Lay second sheet of phyllo over bottom, but this time drape it up and over the left side of the pan. Brush with melted butter. Continue laying the rest of the phyllo in the pan this way, alternating sides as you go.
Spoon greens mixture into bottom of pan. Top with mushrooms; top those with feta. Fold phyllo up and over the filling, sheet by sheet, overlapping them as you go. Brush each layer with a little melted butter. Sprinkle top with walnuts. Bake until phyllo is nicely browned, 30 to 35 minutes. Serve warm or at room temperature.


text:
After 10 seasons as a pro basketball player, with an NBA title and two All-Star appearances, Sean Elliott could easily have lost his passion for the game. But as the San Antonio Spurs forward anticipated his return to the lineup, he experienced all the excitement—and butterflies—that the rawest rookie might feel. "It's not every day," says Elliott, 32, "you do something that's never been done before."
When he stepped onto the court March 14 at the San Antonio Alamodome to an emotional standing ovation, Elliott was indeed breaking new ground, becoming the first major-league athlete to return to action after receiving a transplanted kidney. Scoring 2 points in 12 minutes of play—just under seven months after Elliott received the kidney from his brother Noel, 33—proved an inspiration for fans and teammates alike. "Every time I see his enthusiasm," says Spurs center David Robinson, "I realize how fortunate we are to do what we do."
In his career, Elliott had known little but good fortune until June 1993, when severe fatigue and a swollen face and arms led him to visit his doctor. "I just thought it was the stress of the season," says Elliott. When tests detected an unusually high protein level, he learned he was probably suffering a kidney ailment. "I was told I could live with it for the rest of my life," Elliott recalls, "and most likely I'd have a remission."
Despite occasional injuries, Elliott played the following season for the Detroit Pistons, then in 1994 returned to the Spurs, where he was a stalwart, averaging 18.1 points per game and gaining a reputation as one of the league's most explosive and graceful players. But by March 1999 he was feeling fatigued again. This time his kidney specialist John Rienieck detected such high levels of waste products in Elliott's urine that he advised him to consider a transplant before he ended up on dialysis. "I was a little shocked," Elliott says, "I thought this might end my career." Though he continued to play through the playoffs, "his energy level was lower every game," says Spurs coach Gregg Popovich. That didn't stop him from averaging 11.9 points in the postseason, helping the Spurs to the NBA championship.
Then, just days after the Spurs' victory parade, Elliott was diagnosed with focal glomerulosclerosis—a disorder causing chronic scarring of the kidney tissue—and was told it was time for a transplant. "I couldn't believe it was happening," he says. Family members submitted to tests, and within days a donor emerged—Noel, a Tucson stock clerk. "Noel had a grade-A kidney: young, healthy, good size, good blood vessels," says the transplant surgeon, Dr. Francis Wright.
He also had a good attitude. Sean had been close to Noel, just 15 months his senior, since their boyhood in Tucson as the children of Odiemae Elliott, now 62, a retired nurse, and her husband, Robert, 59, a medical technician. (Divorced in 1978, they also have a son, Robert, 37.) "They're so much alike it's scary," says Odiemae of Sean and Noel. Despite anxiety about the procedure, Noel never hesitated. "His need," he says of his brother, "was greater than my fears."
On Aug. 16, the brothers arrived at San Antonio's Methodist Specialty and Transplant Hospital. "I just held his hand," says Sean. "We didn't say anything. He understood how I felt about what he was doing." In a four-hour procedure, doctors removed one of Noel's kidneys, and then, in a three-hour operation, placed it in Sean's pelvic area. Noel recovered quickly and Elliott was back on his feet within a week, determined to return to the court. He was lifting weights by September and in October started running the Alamodome's stairs. "From one week to the next," says Elliott, "I was getting better, better, better."
His coach was more eager to see Elliott healthy than playing. "I don't want this miracle to become a tragedy because we want him there to win a few more games," says Popovich. But Dr. Wright encouraged his patient's efforts, which he says pose minimal risks. (Still, doctors will closely monitor his blood chemistry.) Elliott—separated from his wife, Akiko, 29, mother of his daughter Jordyn, 22 months—saw his return as a worthy goal. "It's a great challenge for me," he says, "and I can touch a lot of people in a positive way." He still hasn't found a way to thank his brother. "I just told him," says Noel, "to come and see me when we're both old men, and we can chat about the good old days."
Thomas Fields-Meyer
Michelle McCalope in San Antonio
On the Rebound
updated 03/27/2000 AT 01:00 AM EST
•originally published 03/27/2000 AT 01:00 AM EST


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Land Use
What we do
MAPC provides a number of programs for municipalities in our region, including: preparation and implementation of MetroFuture; advising the MAPC Legislative Committee and Executive Committees regarding land-use-related proposed legislation; staffing the eight MAPC subregions, which provide forums for municipal officials and other community leaders to discuss open space, housing, economic development, transportation and other issues of mutual interest; and provide technical assistance to individual, or groups of, municipalities on a range of land use and zoning issues, including open space and recreational use planning.
District Local Technical Assistance and
Planning For MetroFuture Technical Assistance
Learn about MAPC's Technical Assistance initiatives and projects.
Recent Projects
New Initiatives
Art and culture add vibrancy to places and neighborhoods, and can be an integral part of community planning. Learn more about the arts and culture goals and strategies outlined in our MetroFuture regional plan and about the resources and technical assistance we can provide: www.mapc.org/art.
MAPC reports and toolkits:
- Managing Neighborhood Change: Anti-Displacement Strategies Toolkit
The Conservation Subdivision Design (CSD) Project (July 2000)
Medical Marijuana:
Medical Marijuana Planning Resources from November 14, 2013 Roundtable Discussion
External Resources:
- Comprehensive Land Use Reform and Partnership Act (CLURPA) Documents: CLURPA Summary 5.18.10CLURPA with annotations 5.18.10
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Contact Land Use Division Manager Mark Racicot at (617) 933-0752, or email firstname.lastname@example.com.


text:
Jordan De Melo
"NES Master"
- Total Points:
- 39,561
- Rank:
- Justin Bieber Fan
- Last Visit:
- 12/08/2009
- Currently:
- Offline
- Sex:
- Location:
- Toronto, ON
- XBox Live: T O 5011 ers
My Favorites
Favorite Music:
Big Sugar,
The Trews,
Rolling Stones,
Pink Floyd,
Led Zepplin,
The Darkness
Favorite Books:
The Davinchi Code,
Deamons & Angels,
Stupid White Men,
anything by George Carlin
Favorite TV Shows:
Chapelle show,
Joe Schmoe,
Daily Show and other shit I can't think of.
Favorite Movies:
Kill Bill,
Bowling for Columbine,
Farinhiet 9/11,
Batman Returns,
Indiana Jones Trilogy,
Back to the Future Trilogy,
Toy Story (1&2),
21 Grams
Favorite TV Shows:
Chapelle show,
Joe Schmoe,
Daily Show and other shit I can't think of.
Favorite Movies:
Kill Bill,
Bowling for Columbine,
Farinhiet 9/11,
Batman Returns,
Indiana Jones Trilogy,
Back to the Future Trilogy,
Toy Story (1&2),
21 Grams
My Interests
Interests:Collecting NES Games, Hockey, Video Games
Where I work:Anywhere in the Greater Toronto Area.
What I like to do:Play NES, Collect NES Games, Listen to Music, Play Road Hockey just good 'ol Canadian stuff.
My Tastes:chocolate, salty and crunchy(LOL)
My Clubs
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The place for the Latest Nintendo News and Rumors. With that said...
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Game Informer said it best in one of their E3 2004 articles:...
Mario Kart DS Online!!!
Mario Kart DS Online!!!
Nov 26, 2005 9:59PM PST
Later all,
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text:
Created in this Craftsy class
Learn wire-wrapping methods to make seven sophisticated jewelry projects! Create beautiful earrings, necklaces and pendants to complement your wardrobe.
Other projects made as part of this class:
Offer some kudos...
Join the conversation...
Ask a question...
Add your comment...
|Here are some details about my project:
|Earrings, Accessory
|Traditional, Casual, Cute, Holiday, Classic
What materials did you use? The frame of the Scilla earrings have been made from scratch using gold filled wire. Attached to it is a beautiful oval shape faceted blue swiss Topaz and the frame is also decorated with faceted rondelles of blue quartz. The earrings measure 2" and the blue Swiss topaz measures 11mm*8mm.
I love the use of copper color wire in this one with the blue stone. It's a beautiful contrast.


text:
About Us
Submit Press Release
Mobile & Palm
Games & Entertainment
Acamar Rising
Acamar Rising Full Description
A 3D space shooter where a lone fighter must defend a space station.
Full Description
Beteo Software and Games
14, December 2005
39049 Kb
$19.95 to buy
Download Acamar Rising »
Product Info
Acamar Rising is a 3D space shooter where a lone fighter must defend a space station against the many threats of space, from asteroids to aliens. The fighter pilot who defends the station may be lone, but he isn t without some hefty resources at his disposal. With four power-ups to be found in asteroids and 8 different weapons to purchase, the defending ship will go from bucket of bolts to deadly as sin faster than you can say hyperdrive, and he is going to need it. Assaulting the station is a variety of threats, the most common of which are asteroids and comets, which hurtle towards the station. Let too many of these items past and there won t be anywhere to left to dock! Also alien crafts will continuously assault and harass the defenses, along with the occasional mother ship.
What's new in current version
New Particle effects, Tutorial, Better Graphics, Fixed asteroid flicker, Improved AI!
DirectX 9 or above, 1.4g processor or higher with 64mb video card
Please contact Acamar Rising publisher,
Beteo Software and Games
if you have questions or issues regarding this product.
Share Acamar Rising Review, Battle aliens in a quest to clear asteroids. Page
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For one reason or another, I never got around to playing much of Metal Gear Solid. I have owned the game on PS1 since shortly after its original release, but I was 17 at the time and easily distracted away from video games. I believe I managed to save the Darpa chief before I shelved the game for many years.
Well, I finally got around to playing the game in its entirety. It probably isn't fair for someone to review a game like this, this many years after its release. It was released near the birth of mainstream console 3D games and the developers knowledge and the technology of the time limited these games. These games often just don't age as well as 2D games. Still, I did enjoy my time with the game. I played parts of it on my PS3 and parts on my Vita. As with all PS1 classics, the game looks significantly better on the handheld.
Metal Gear Solid is a stealth/action game. The gameplay honestly may have aged worse than the graphics in a lot of ways. Quite often I would have difficulties turning corners and would end up with Snake throwing his back to the wall just long enough to be spoted by the enemy. The combat is very similar to the original Resident Evil in where you have very little control of what you are aiming at (with most weapons at least). The best method seems to just spray your gun like a waterhose back and forth and hope for the best.
I am sure if I had played the game through during its release the plot, cutscenes and acting would have been very impressive. There is a lot of spoken dialog in the game, more than I can personally remember there being in any PS1 game. Compared to games like Resident Evil, the acting is Oscar-worthy. By today's standards, not so much.
The storyline is still very videogame-ish. Everyone has dramatic speeches at the most rediculous times. People will stop and tell you their life story before, after and during battles. It also seemed to follow the rule of the more plot twists, the better. Allies stab you in the back and your enemies suddenly have a change of heart and help you out before the finally die of the wounds you dealt them.
Everyone also seems to think they are an animal in this game. Many characters (such as Snake) have an animal nickname and they take on those roles very seriously. They justify their actions by what their corresponding animal would do under similar circumstances. It almost felt like they all really wanted to be Batman characters or something and felt very out of place in this world.
The game also shows some very strange design decisions. Portions of the game seem like they would have been impossible without the use of a guide. One battle requires you to switch your controller to port 2 in order to win a fight for example. A few times it just was not very clear which direction I should be headed.
This game also was released near the end of the FMV-craze. When home consoles first started having CD drives, developers felt compelled to put full motion video into the game and I was reminded of this when playing MGS. These sequences feel very out of place and usually just made me laugh and shake my head as I remembered the state of games at the time of this release.
Despite all of these issues, I did have fun with the game. I have complained recently about pacing in modern games. A lot of games today go out of their way to drag on and to pad the time spent playing their game. This makes sense from a developer perspective - who wants to spend $60 for an 8-hour experience when others are offering 100+ hour experiences at the same price? The problem is most games are still far from over by the time I start to tire of the experience, yet I force myself to the end so I don't miss the experience.
MGS has great pacing (as long as you don't spend 5 hours trying to figure out why you can't kill a boss without switching the controller port). The entire game can be completed in 10 to 12 hours. There isn't too much back-tracking. During that short time, there is quite a variety of gameplay elements. Every section in the game feels handcrafted, instead of "we already added this gameplay element, lets find a way to make the player do it 20 times instead of just this once".
Overall, I found Metal Gear Solid to be about what I expected. It is a solid, well-crafted game that has not aged terribly well. It managed to keep my interest well enough to see past its issues developers have long since overcame (for the most part). Most importantly, it didn't waste any of my free time and tell me it was "value".
Final Grade: B


text:
This is a discussion on [News] Linux Collaboration Summit, "Make the Move [to Linux]" Creator Interviewed - Linux ; The Linux Collaboration Summit starts shortly... https://www.linux-foundation.org/eve...ration/program Moving to Linux? No fear, help is at hand ,----[ Quote ] | To some people, the increasing number of Linux distributions serves as a | disadvante when it comes to attracting new ...
The Linux Collaboration Summit starts shortly...
Moving to Linux? No fear, help is at hand
,----[ Quote ]
| To some people, the increasing number of Linux distributions serves as a
| disadvante when it comes to attracting new users. To Christopher Smart, it's
| a plus point - the way he puts it, if he had not been able to roll his own,
| he never would have achieved the level of understanding of Linux he has
| today.
"The number of developers working on improving Linux vastly exceeds the number
of Microsoft developers working on Windows NT."
--Paul Maritz, Microsoft
Linux kernel developers have tripled in number
,----[ Quote ]
| The Linux Foundation (LF) has published a study on Linux mainline kernel
| development. According to LF, the number of Linux kernel developers has
| tripled since 2005, with many more companies contributing to the process
| (including, potentially, the latest new LF member, Adobe). Â*
Linux kernel community grows, but elite group remains
,----[ Quote ]
| Viro has contributed 1,571 changes to the kernel, which sits at the core of
| the Linux operating system, over the past three years, according to a new
| report from the Linux Foundation. That's more than any other individual
| developer, the report states. In contrast, Torvalds, the kernel's creator and
| steward, contributed 495 changes. Viro couldn't be reached for comment about
| the report. Â* Â*
| [...]
| But this group of coding superstars sails atop a roiling sea of newer
| community members, notes Jim Zemlin, executive director of the Linux
| Foundation. Roughly 3,700 developers from more than 200 companies have
| contributed to the kernel since 2005, according to the report. Â*
Linux contributor base broadens
,----[ Quote ]
| With more companies funding Linux work, the core hackers now delegate
| 70% of the coding
Amazing 3D view of linux kernels..
,----[ Quote ]
| These are 3D renderings of dependencies in the Linux kernel source code.
Microsoft's death knell for Windows Mobile
,----[ Quote ]
| And of course, there's Linux - which already runs on hand-held devices
| without much fuss. That'll be in a much stronger position if and when the x86
| architecture becomes a potent part of portable life. Â*


text:
In tonight's TV Picks, a new group of housemates lock themselves away for the summer, catch up on one of HBO's big series before its return, and see why Jane Seymour got arrested for prostitution.
Let's go straight to the bullets:
- "Big Brother" (7 p.m. on CBS, cable channel 12): The reality show returns for a 15th season. Episodes will air three times a week -- Sundays beginning this weekend, Tuesdays beginning July 2 and eliminations on Wednesdays beginning July 3.
- "MasterChef" (7 p.m. on FOX, cable channel 13): Chefs face mystery ingredients, the return of Season 3 winner Christine Ha and a wedding party.
- "Franklin & Bash" (8 p.m. on TNT, cable channel 42): Jane Seymour returns as Pete's (Mark-Paul Gosselaar) mom, who's been arrested for prostitution thanks to her work as a sex therapist.
- "Royal Pains" (8 p.m. on USA, cable channel 25): Hank (Mark Feurerstein) finds something surprising when he investigates Boris' (Campbell Scott) death.
- "The American Baking Competition" (8 p.m. on CBS): Bakers are required to stagger their start and finish times in a new contest.
- "The Newsroom: A Special Report" (8 p.m. on HBO, cable channel 651): Catch up on the first season of the Aaron Sorkin drama before it returns July 14.
- "How to Live with Your Parents (for the Rest of Your Life)" (8:30 p.m. on ABC, cable channel 8): In the series finale, Polly (Sarah Chalke) tries to get her daughter into the school's gifted program and discovers something about herself in the process.
- "Futurama" (9 p.m. on Comedy Central, cable channel 53): Fry gets marooned on a distant planet and tries his best to phone home.
So, what are you watching?


text:
TWO THOUSAND eleven will go down as the year that Miller Brewing finally repented.
Here is a company whose top seller, Miller Lite, forever stands with McDonald's and "American Idol" as the archetypes of dumbed-down American culture, whose pursuit of the lowest common denominator brought us an utterly vile beverage with no redeeming quality other than its ability to pass through the human anatomy undetected.
Yes, Miller Lite remains the company's top seller. But you wonder for how long.
For, in 2011, the company not only aborted its hugely unpopular spin-off, MGD 64 Lemonade - a sign, perhaps, that the days of large breweries cynically foisting yellow by-products on an unsuspecting public are numbered. It also committed itself to an outstanding, black-as-ink stout that is the flavor- and moral-opposite of light beer.


text:
When You're Serious About Meeting Someone.
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Create your free profile and search for gay women in your area, Share photos and videos, flirt and date with other Lesbian girls online. Join our free Lesbian personals, and free Lesbian dating site today!
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Lesbian.Matchmaker.com Same sex dating Lesbian website you can find love for the same sex marriage, Find your soulmate search millions of Lesbian Personals and date other Lesbian women like you now!


text:
Metrogirl / flickr.com
'Veitchii' gardenias are compatible with camellias.
Q: What plants can I add to my camellia bed that need the same soil and light requirements and that would complement the overall look? — F.M., Houston
A: Hydrangeas (deciduous), gardenias, Japanese maples, ferns and temple bells (Pieris) are possibilities.


text:
Since the end of the nineteenthth century, music has played an increasingly prominent role in constructing national identities and promoting various types of nationalist projects. Some of these projects turned to (largely re-invented) musical folk traditions as evidence of the rootedness and longevity of their nations. Later, music was often employed to show the grandeur of nation-states and empires. With the rise of illiberal nationalisms, many composers and performers contributed to the formation of 'closed', exclusivist concepts of national identity.
However, no matter how deeply involved particular composers or musicians might be in promoting illiberal social, cultural or political projects, music cannot, as such, be regarded as nationalist, racist or xenophobic. The racist or nationalist associations of a piece of music might arise from the lyrics that accompany it, but often are constructed from without, from the larger social, historical, political or cultural context. For example, the reasons why 'Giovinezza' is banned in Italy or Richard Wagner's Der Ring des Nibelungen is rarely heard in Israel do not have much to do with the music itself, but rather with the memories these works evoke, the historical or cultural baggage they bring with them. The majority of punk fans don't listen to the songs of Skrewdriver or Macht und Ehre, not because they are 'bad' punk rock but because the band members are racist.
This special issue will feature original research articles focusing on historical and contemporary instances of intersection of music and nationalism. We are particularly interested in contributions that address the following issues:
• musical works as lieux de memoires
• appropriation of folk music in nationalist narratives
• music and racial or ethnic conflict
• the role of music in the demonization or stigmatization or ethnic, racial or national communities
• xenophobic tendencies in contemporary musical genres such as Punk, Industrial, Hip-Hop, Neo-Folk, Dark Ambient, Black Metal and others
• the use of music by historical and contemporary far right movements, organizations and parties
Proposals for articles (500 words) addressing these and related issues should be submitted by e-mail before 15 June 2011. All final contributions must be the original work of the author/s; they will be subject to peer review and the editors' decisions will be final. Please send proposals to Anton Shekhovtsov (email@example.com) and/or Barbara Rosenbaum (email@example.com).


text:
Legal Positivism
Brian Bix
University of Minnesota Law School
BLACKWELL GUIDE TO THE PHILOSOPHY OF LAW AND LEGAL THEORY, Martin P. Golding & William A. Edmundson, eds., Blackwell, 2005
This article tries to present the jurisprudential school of thought, legal positivism, within a larger context than is usual in contemporary English-language discussions of that approach: (1) showing the intellectual and political contexts in which the movement began; (2) emphasizing the variety of theories that fit under that label (e.g., how the Kelsenian tradition varies significantly from the Hartian tradition); and (3) discussing how the future development of legal positivism will depend on its discussion of wider theoretical issues (e.g., the proper approach to social theory, and the use of conceptual analysis in philosophy). The article also summarizes the main criticisms of legal positivism, and gives an overview of the internal debate of inclusive legal positivism versus exclusive legal positivism.
Note: This is a description of the paper and not the actual abstract.
Number of Pages in PDF File: 22
Date posted: January 24, 2003
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text:
Programs & projects
Aboriginal client service specialists
|Aboriginal client service specialists
|New South Wales. Dept. of Justice and Attorney General;
|The program seeks to improve the quality of court related services for Aboriginal victims, court users and their families. ACSS roles can vary slightly differently across locations, in response to local circumstances. ACSS are based within the local court in the communities where they are located. The objectives of the program are: to ensure that Aboriginal defendants, victims and families understand the outcome of their court matter; to improve community awareness and understanding of court processes; to improve community awareness and accessibility of justice related support services, including victims services, time to pay applications, mediation and civil court services; to improve the capacity of non Aboriginal staff to provide culturally competent services to Aboriginal clients; and to improve relationships between Aboriginal people and courts. In addition to front-line client service, ACSS also facilitate community education sessions and provide outreach services that take the court services out to a community setting and allow clients to access support within their own communities, rather than in the court.
|Date commenced
|In progress
|Target group
|Aboriginal and Torres Strait Islander only;
|State / territory
|New South Wales;
|Courts and sentencing; Legal services; Program;
|The ACSS program was evaluated in 2005 and the following achievements were noted: a reduction in the number of 'fail to appears' in courts with ACSS officers; registry staff reporting a reduction in conflict between Aboriginal clients and staff; a high le; vel of support from key stakeholders, including police, legal professionals and magistrates.;


text:
LG Viewty KU990 3G 5MP Mobile Phone
One of the biggest flaws is the scroll wheel, and here comes the real killer. Since this is apparently as much camera as it is phone, every time you use the scroll wheel you end up putting your greasy fingerprints on the lens as there's no lens protector. This means you end up having to clean the lens every single time you want to take a photo. We're also not so sure about the raised edge around the lens and the zoom ring/scroll wheel, as our review unit seemed to have taken a few knocks before we got it and the finish was already wearing thin on parts of the scroll wheel.
Having a protruding lens also means that the phone will rest on it when you put it down on a desk, which could possibly add further wear to the camera parts and even cause damage to the lens. We're not keen on this design and we think LG should go back to the drawing board for the next model and design something with a lens cover and move the scroll/zoom controls to the side of the device; having another button or two really isn't a big deal.
Another minor issue is that the Viewty isn't SDHC compatible, so you're limited to using 2GB memory cards. This might not be a big deal unless you want to take a lot of pictures and videos as well as being able to use the Viewty as your portable music and video player. You'll always have to compromise, but the lack of SDHC on a brand new device like this is quite frankly a bit odd.
Battery life seemed to be decent with quoted talk times of 355 minutes on 2G, 233 on 3G and 138 minutes of video call time. The battery should last about 434h in standby on a 2G network and oddly enough up to 454h on a 3G network according to LG. The battery seemed to last ok during the time we had the phone, but it's always hard to assess battery life, though it compares pretty well with other similar devices.
So is the Viewty a beauty or a beast? Well, it has some good features and it has some that are frustrating to use, but overall it's not a bad phone if you're looking for something out of the ordinary. LG needs to tweak the software a bit more to make it compatible with a wider range of files that it's supposed to support, and the UI could do with being tweaked a bit to remove some confusing options. But if you're looking for a stylish, albeit somewhat basic smartphone with one of the better mobile phone cameras out there, then this might be what you've been waiting for.
It seems to be limited to Europe and Asia at the moment and the final hurdle would be the price, although that is somewhat dependant on the deals your network offers. Without a contract you're looking at around $683 AU + tax converted from what Expansys sells it for in the UK, which is not terrible compared to say the Prada phone which the same company retails for about $552 AU + tax, and it compares quite well to what it is selling for in Taiwan which is $697 AU, although this includes tax.
PRICING: You can find products similar to this one for sale below.
United States: Find other tech and computer products like this over at Amazon's website.
United Kingdom: Find other tech and computer products like this over at Amazon UK's website.
Canada: Find other tech and computer products like this over at Amazon Canada's website.
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text:
Imagine a world, in which there is nothing to be afraid of. Neither natural phenomena, or even new trends in art. Unusual admire a breathtaking… All this – The most exclusive resort in the world: "Bulgari Bali Hotel & Resort". Well-known hotel brand Bulgari has opened the hotel on the Bali and has not lost to the location, because it is really a paradise on earth.
Location of One of The most exclusive resort in the world: Bulgari Hotel Bali
On top of the 150-meter cliff that descends to the white 1.5 miles of beach, lapped by the clear waters of the Indian Ocean, luxurious villas Bulgari Resort Bali, reflects a modern interpretation of the traditional architecture of Bali – the result of creation by Italian architect Antonio Citterio, representing famous brand Bulgari.
The hotel offers just 59 luxury villas, made using volcanic rocks in Indonesian style: elegant buildings with roofs made of wood-Elango Elango, beautiful bronze lanterns at the entrance, and a cozy patio with a garden. The rooms – stylish interiors that combine modern Italian design and the tradition of the island of Bali, decorated with exotic wood and stone, fine furniture and decorated with original features and antiques and local artwork.
Design of One of The most exclusive resort in the world: Bulgari Hotel Bali
Designers and architects have done without the fear of a miracle, is unlike anything else. Geometric lines, elegant style, all kinds of colors – all this successfully absorbed the hotel. The decoration of the villas used by hand hewn volcanic stone, and exotic species of trees, giving the buildings of extraordinary charm and complete harmony with nature. Inside the rooms are upholstered furniture, bright colors, exclusive curtains and canopies.
Brand Bulgari (Bvlgari) is known throughout the world as the epitome of elegance, authority and of the highest quality. It appeared in the XIX century in Rome and named for the founder of the company, hereditary jeweler Bulgari Sotirio Greek origin.
The letter V instead of U in the title appears in the tradition of the ancient classical Latin alphabet. The classic time the true mark of only uppercase letters (Romans originally used only one form of letters). That is why the form of writing BVLGARI, Bvlgari and Bulgari equivalent.
Under the brand name «Bulgari» develops hotel chain Bulgari Hotels & Resorts, one of the hotels that was in the open and in Bali.
The most exclusive resort in the world photo gallery:
Thanks for photos to Bulgari Hotels and Resorts


text:
Earth is an old planet, and her teeming masses are running out of resources - and time. It is up to men such as Jeff Holman to discover a haven for Earth's millions. Altair VI is one such planet, and Holman is determined to transform this world into one where the human race can survive.
Star probes long ago informed Earth that Altair VI had a flourishing ecology with one very tough beast at the top of the food chain, one that will have to be dealt with before the human colony ships arrive. The beast is not only tough, it is as smart as a man.
Holman is faced with a soul-wrenching decision - for to make Altair VI habitable for humans, all native life must die.
©2013 Ben Bova (P)2013 Blackstone Audio
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text:
Web browser Do Not Track settings are no longer enabled on Yahoo. Users receive a personalized experience by default. Change settings.
Yahoo! ("we" and "us", as the case may be) takes your security seriously and takes reasonable steps to protect your information. No data transmission over the Internet or information storage technology can be guaranteed to be 100% secure. The following is a summary of the measures we take to protect your information and descriptions of ways we implement these measures for different types of information you may provide to us. Please see our Security Centre for additional information on how to reduce your security risk when online.
We continue to evaluate and implement enhancements in security technology and practices, however we can only take steps to help reduce the risks of unauthorized access. Each individual using the Internet can take steps to help protect their information and further minimize the likelihood that a security incident may occur. We describe some of those measures and provide links to information that may be helpful in these pages and within our Security Centre.Security Steps We Have Taken
In the event that you believe that your personal safety is at risk or if you believe that you may be the victim of identity theft or other illegal conduct, please contact the appropriate law enforcement agencies directly.
+ Security Center is serviced by Yahoo! Inc.


text:
Weekend Top 10
By Sarah Story, Citizen Events Editor 01/03/13
The film "My Fair Lady" will play at the Henrico Theatre, 305 E. Nine Mile Rd., at 7 p.m. Jan. 4 and at 2 p.m. and 7 p.m. Jan. 5. Tickets are $1 and can be purchased at the door. For details, call 328-4491 or visit http://www.henricorecandparks.com.
Wear your pajamas, bring a pillow and watch a classic holiday flick starring Dr. Seuss' meanest and greenest character at 2 p.m. at Twin Hickory Library, 5001 Twin Hickory Rd. All ages welcome. For details, call 290-9200 or visit http://www.henricolibrary.org.
Comedian Tony Rock will perform at 7:30 p.m. Jan. 4, 7 p.m. and 9:30 p.m. Jan. 5 and at 7 p.m. Jan. 6 at the Richmond Funny Bone Comedy Club in Short Pump Town Center. Rock, younger brother of comedian Chris Rock, has been on television and the big screen and his "Comedy Central Presents" special aired in 2010. Tickets are $15 to $17. For details, call 521-8900 or visit http://www.richmondfunnybone.com.
The Greater Richmond Branch of the American Association of University Women will hold a meeting at 10:30 a.m. at the Kroger Training Center, 2235 Staples Mill Rd. Guest speakers Lois Hofstra and Earl Rogers will give an overview of the Road Scholar – Adventures in Learning program. There will be an opportunity for questions and input. For details, visit http://www.aauwbonairva.org.
IMANI Place, 6 W. Nine Mile Rd., will host an Epiphany/3 King's Day Celebration from 11 a.m. to 3 p.m. There will be live animals, period costumes, local talent, poetry, music, dancers, a Kids Corner, food and more. Admission is free and open to the public. For details, call 486-9200.
Andy Vaughan & The Driveline will perform at 8 p.m. at McCook's Lakeside Grill, 5516 Lakeside Ave. Enjoy a night of country music, honky-tonk and western swing. For details, call 266-2717.
St. Stephen's Episcopal Church, 6000 Grove Ave., will begin its Season of Light January performance series with an All-Bach Concert at 8 p.m. The Eckhart Ensemble, a baroque orchestra, and Sanctuary, St. Stephens' Compline choir, will perform. A light reception will follow. Admission is $15; students are admitted free. For details, visit http://www.saintstephensrichmond.net/performance.
Kitchen Thyme, 7801 W. Broad St., will host an indoor winter market every Saturday through April from 10 a.m. to 1 p.m. There will be up to 15 local food vendors and artisans each week. For details, call 396-2665 or visit http://www.kitchenthymerva.com.
Messiah Lutheran Church, 8154 Atlee Rd., will host its sixth annual Epiphany Celebration at 6:30 p.m. There will be activities for young children and a reception will include "Epiphany Cakes" that contain a surprise. A sprig of Christmas greens may be brought to burn that will be used for Ash Wednesday. Donations of gloves, scarves and socks will be collected for the homeless. For details, call 776-7134.
Children ages 4-5 are invited to "Enchanting Icicles," a workshop on how these icy marvels are formed, from 1:30 p.m. to 2:30 p.m. at Three Lakes Nature Center, 400 Sausiluta Dr. Cost is $6. To register, call 262-5055.
Reynolds CC to host sculptor Paul DiPasquale
Reynolds Community College will host Richmond sculptor Paul DiPasquale Sept. 28 as he shares his presentation "Art Talk, Why Art Matters" from 6 p.m. to 8 p.m. in the Conference Center Gallery of the Workforce Development and Conference Center on the Parham Road Campus, located at 1651 E. Parham Road in Richmond. This event is free and open to the public. > Read more.
Free children's clothing for those in need
The Children's Clothing Closet at Highland Springs United Methodist Church will be open Saturday, Aug. 27 and Tuesday, Aug. 30 to provide free new or nearly new children's clothing for families in need, prior to the start of the school year. The Clothing Closet will be open from 10 a.m. to noon both days. The church is located at 22 North Holly Avenue. > Read more.
Weekend Top 10
For our Top 10 calendar events this weekend, click here! > Read more.
Henrico to offer four home maintenance workshops
Glen Allen Day in photos
No one injured in Eastern Henrico shed fire
Business in brief
Tuckahoe meeting Sept. 28 to detail bond referendum projects
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Sep. 15, 2016Click here to read the print edition.
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Deadline nears for 'Henrico Live' ticket purchase
CAT Theatre announces cast for October show
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Obituary – Mildred Terrell Tate
Obituary – Stephen Embry Esbach
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CalendarNOVA of Virginia Aquatics will present the 8th annual C&F Bank/Mix 98.1 Short Pump Mile and Express Fun Run. The race will be held behind Short Pump Town Center near… Full text


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Dance of Souls
New set by BritneySiren & HIPhotos
Rainbow Power Pits
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Looking for models to create sets with, in OC, CA
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Brides.com: What inspired the pink-and-orange color scheme?
JS: My bridesmaid dresses were mango—kind of a pinky orange, so I think that's where it stemmed from. It was simple, but the pink-and-orange color scheme really brought everything together so well. The invitations even asked guests to wrap their presents in pink and orange wrapping paper.


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Marshall leads by example
Follow the Friends Life t20 on ecb.co.uk - click here for exclusive interviews and videos, live scores, match reports, photo galleries and much more
Hamish Marshall led from the front as Gloucestershire boosted their hopes of a quarter-final place with a seven-wicket Friends Life t20 win over Midlands/Wales/West Group leaders Worcestershire at Bristol.
The skipper hit a scintillating 72 off 49 balls, with six fours and a maximum, sharing a second-wicket stand of 142 in 15 overs with impressive Australian debutant Ed Cowan, who made 70 as the hosts chased down a target of 160 for victory with 12 deliveries to spare.
Worcestershire had posted 159 for six after winning the toss, Gareth Andrew top-scoring with 43 and captain Daryl Mitchell hitting 31 off just 13 balls. Spinners Ed Young and Muttiah Muralitharan stood out for Gloucestershire, conceding only 43 from their combined eight overs.
It looked likely to be a testing target on a slow pitch. But after losing Benny Howell in the opening over for a first-ball duck, the home side quickly took control, Marshall reaching a 35-ball half-century, having been badly dropped on 14 by James Cameron at deep square off David Lucas.
Australia A captain Cowan emerged from a sketchy start to also strike the ball handsomely, making his runs off 48 deliveries, with nine fours and two sixes. By the time Marshall was out only 17 runs were needed.
The result put Gloucestershire on nine points, just one behind Worcestershire, Somerset and Warwickshire with each team having two games left to play.
Worcestershire suffered a major blow when Moeen Ali was bowled by the second ball of the match from Ian Saxelby, having hit the first through the covers for four.
The visitors struggled to gain any momentum as Phil Hughes drove a catch to mid-on off Liam Norwell and Vikram Solanki, on 22, was taken at extra-cover off Young, Marshall the catcher on both occasions.
Cameron did his best to stabilise the innings with a run-a-ball 32 before being caught at third man by Cowan off James Fuller.
It was Mitchell who provided the necessary acceleration, hitting six fours, and taking the pressure off Andrew, who blossomed himself to strike two sixes and four other boundaries.
After Young and Muralitharan had bowled so economically, the last four overs went for 55 as seamers Norwell, Fuller and Saxelby lacked control under the onslaught from Mitchell and Andrew.
Want to know what's happening at your county? Interested in how your rivals are faring? Look no further than ecb.co.uk's county-by-county page


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Dark energy is a form of energy that, while never having been directly observed, is hypothesized to exist to explain observations that the universe is expanding at an accelerating rate. The expansion of matter in the universe was originally assumed to be decelerating due to the attractive force of gravity, but observations in 1998 of the accelerating expansion of the universe required a new explanation for what continues to push galaxies apart. Dark energy is this negative pressure, but more is unknown about it than known. Despite how poorly we understand it, dark energy accounts for nearly three quarters of the total mass-energy of the universe.
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In science there are many key concepts and terms that are crucial for students to know and understand. Often it can be hard to determine what the most important science concepts and terms are, and even once you've identified them you still need to understand what they mean. To help you learn and understand key science terms and concepts, we've identified some of the most important ones and provided detailed definitions for them, written and compiled by Chegg experts.


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Maybe it is where you belong. According to the jingle it is, anyway.
And at least two Friends & Neighbors readers like to go there, as proven by the fact that the Globe-News recently received two separate recipe requests for menu items from Applebee's Neighborhood Grill and Bar - the same week.
Wyvonne Webb is interested in obtaining the national chain's recipe for Spinach and Artichoke Dip. Jacqueline Brown, meanwhile, wrote that she would love to have the recipe for Applebee's Santa Fe Chicken Salad.
We contacted the Applebee's Restaurant on Soncy Road and were referred to their corporate offices. Corporate representatives were unable to approve our requests by press time.
But never fear, a little detective work turned up a yummy-looking recipe for a Spinach Artichoke Dip and, at least, the ingredients for the Applebee's salad.
The Web site
provided the Spinach Artichoke Dip ingredients, while a Web site titled
provides a message board for posters to leave recipes of America's favorite brand-name foods, the site said.
An Applebee's employee, presumably, left the ingredients for the Santa Fe Chicken Salad on the site; but no amounts and no real specifics.
The instructions state: Mix salad mix, tortilla strips, mexi-ranch dressing (ranch dressing mixed with salsa), Monterey jack and Cheddar cheeses in a bowl. Top with sour cream, guacamole and pico de gallo. Marinate chicken in various spices and place on top.
Although we don't know what brands are used for each ingredient nor the specific spices (which is the real secret), this should provide at least a similar dish.
As for Spinach Artichoke Dip, the recipe is provided below, along with another for Brown, who was looking for a good coleslaw recipe.
The Meals For You site contained a delicious-looking recipe for Apple Coleslaw.
Spinach Artichoke Dip
2 teaspoons unsalted butter
2 tablespoons plus 2 teaspoons chopped onions
7 ounces frozen chopped spinach, thawed and drained
9 ounces canned artichoke hearts, drained and chopped
2/3 cup grated Parmesan cheese
1 clove garlic, minced
[ teaspoon Worcestershire sauce
} teaspoon lemon juice
[ teaspoon curry powder (optional)
Preheat oven to 350 degrees Fahrenheit. Melt butter in a heavy nonstick skillet over medium-high heat. Saute onion 3-4 minutes until softened. Press out excess moisture from drained spinach. Stir in remaining ingredients and transfer to a baking dish. Bake 20 minutes or until bubbly. Serve with tortilla chips.
Per serving nutrition facts: 138 calories, 7.3 grams fat, 45 percent calories from fat, 18 milligrams cholesterol, 10.5 grams protein, 9.7 grams carbohydrates, 6.0 grams fiber, 387 milligrams sodium.
Apple Coleslaw
6 ounces packaged shredded cabbage
1/3 cup raisins
3 tablespoons mayonnaise-type salad dressing
3 tablespoons plain nonfat yogurt
2 apples, cored and coarsely shredded
Combine all ingredients and salt to taste in a bowl. Toss gently to combine. Chill and serve.
Per serving nutrition facts: 163 calories, 8.5 grams fat, 45 percent calories from fat, 6 milligrams cholesterol, 1.2 grams protein, 22.3 grams carbohydrates, 1.9 grams fiber, 76 milligrams sodium.
Recipes courtesy of Meals For You. Visit
for more information.
© 2016. All Rights Reserved. | Contact Us


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Illness, accident, bereavement and other personal circumstances may affect a student's academic performance when completing course work or sitting examinations. When advising students in such circumstances, it is important that academic advisers and departmental tutors make it clear to students that they must fill in a Submission of Mitigation form (available from the Student Services Centre (SSC). Detailed documentary evidence (eg medical note, death certificate, legal documentation) should be attached. The letter and supporting documentation must be submitted to the SSC (Room G.14 on the ground floor of the Old Building) no later than seven days after the student's last timetabled examination or formal assessment (eg dissertation). The evidence is then passed to the Sub-Board of Examiners for consideration.
Academic advisers or departmental tutors advising students in these circumstances may ask for copies of such documents, but the originals must be submitted to the SSC. Information on these matters is provided directly to students in the 'Instructions to candidates' issued via LSE for You with their personal timetables. It is important to note that mitigation does not lead to any mark changes. Rather, it is taken into account at final classification stage, when the Board can amend the class of degree in borderline cases.
LSE100: The LSE100 final examination is held in January (week 0) of students' second years. The LSE100 Sub-board of Examiners will consider mitigating circumstances in the same manner as for other courses.
For further details see: Mitigating circumstances during the examination period at lse.ac.uk/mitigation|.
Use of this website is subject to, and implies acceptance of, its Terms of use (including Copyright and intellectual property, Privacy and data protection and Accessibility). The London School of Economics and Political Science is a School of the University of London. It is a charity and is incorporated in England as a company limited by guarantee under the Companies Acts (Reg no. 70527).The registered office address of the School is: The London School of Economics and Political Science, Houghton Street, London WC2A 2AE, UK; Tel: +44 (0)20 7405 7686


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MARTINSBURG - A Virginia man convicted of murdering a 22-year-old woman and her 3-year-old son was sentenced Monday to two consecutive life terms in prison and an additional 20 years behind bars for setting fire to the victims' home.
Antonio Prophet, 36, of Lorton, was found guilty in July of two counts of first-degree murder and one count of first-degree arson following a jury trial in Berkeley County in connection with the slayings of Angela K. Devonshire and her young son, Andre White, on the morning of June 6, 2010, in Bunker Hill.
The jury made a no-mercy recommendation, meaning Prophet will spend the rest of his natural life in prison without the possibility of parole. West Virginia 23rd Judicial Circuit Court Judge Christopher Wilkes, whom a defiant Prophet called "incompetent" and a "clown," sentenced Prophet to the maximum 20 years in prison for his conviction on first-degree arson based on Prophet having an extensive criminal history that includes two prior felony convictions.
Article Photos
Antonio Prophet
A full story will be published in Tuesday's edition of The Journal.


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"Sporting News Retweeted W/ Rayven and Troy" is the weekly podcast that talks about what people are talking about in the online world of sports.
Join Troy Machir (@TroyMachir) and Rayven Tirado (@RayvenTirado) every thursday for a look at what's trending and what's not. Remember to subscribe on iTunes to get your weekly fix. Don't forget to get in touch with the show by using the #SNRetweet hashtag.
We're back from a week-long hiatus to bring you the latest and greatest from the social media sports world. Unfortunately, we're in the dullest part of the sporting calendar, meaning social trends are scarce. But that doesn't mean we don;t have things to talk about, because we do, and it doesn't take long for Rayven to make things weird for everyone.
Show subjects include: The passing of Don Zimmer, Colin Kaepernick's new deal, the Baltimore Ravens' response to said new new and the Super Bowl getting rid of italics. We also touch on people who fall asleep at sporting events, noise makers at sporting events, Dan Marino's lawsuit faux pa, Cristiano Ronaldo's voodoo injury and older women dating men much younger than them.
You can probably guess where things start to get weird.


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Voters across Washtenaw County decided the fates of a number of candidates and ballot measures in Tuesday's primary elections.
Three of Ann Arbor's four Democratic mayoral candidates saw their campaign seasons come to an end, as Christopher Taylor moved on to the general election where he will face Independent Bryan Kelly.
In Ypsilanti, Amanda Edmonds became de facto mayor elect as she faces no official opposition on the November 4 ballot.
Ann Arbor City Council primaries also decided the fates of seats in four of the city's five wards.
- Kailasapathy to keep 1st Ward seat on Ann Arbor City Council
- Westphal declares victory in 2nd Ward race for Ann Arbor City Council
- Grand wins 3-way race for Ann Arbor City Council in 3rd Ward
- Warpehoski retains 5th Ward seat on Ann Arbor City Council
Proposal 1 also passed convincingly. The proposal will phase out personal property taxes and replace them with a statewide essential services assessment and a portion of the tax known as the "local community stabilization share."
The nonpartisan judicial races each had two clear-cut leaders advance from crowded packs to runoffs in the general election.
- Julia Owdziej and Tracy Van den Bergh advance to November runoff for Probate Court seat
- Pat Conlin and Veronique Liem advance to general election for Circuit Court Judge
The favorites prevailed in the two United States House of Representatives races that covered the county.
- Debbie Dingell wins Democratic primary in bid to fill husband's congressional seat
- U.S. Rep Tim Walberg likely to run against Pam Byrnes in November election
Freedom Township rejected a measure that would have split the municipality away from the Manchester District Library.
A number of other measures were decided on by voters in Washtenaw County's townships. These results are as of 1 a.m. Wednesday with nearly 90 percent of Washtenaw County's total vote recorded. We will update as results become official.
Ben Freed is a general assignments reporter for The Ann Arbor News. Email him at firstname.lastname@example.com and follow him on twitter at @BFreedinA2. He also answers the phone at 734-623-2528.


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A delay is ordered in the federal trial of Clark County Sheriff Danny Rodden.
The trial was scheduled for next month, but has been moved to March at the request of Rodden's attorney.
In doing so, Rodden waives his right to a speedy trial.
Authorities accuse Rodden of giving a prostitute a deputy badge and uniform shirt and then making false statements about what happened to federal agents.
He's also accused of asking the prostitute to destroy evidence.
Rodden took a leave of absence following his indictment.


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This may be replaced by the bot: Ribchaser is a level 17 rare mob gnoll found patrolling the gnoll camps by the Lakeridge Highway and the Three Corners in Redridge Mountains. He has a 2-3 hour respawn timer. -- Mordsith - (talk|contr) 16:26, 4 January 2008 (UTC)