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Molecular Med focuses on diagnostics and the future of personalized medicine.
By Kevin Davies
May 12, 2008 | SAN FRANCISCO – More than 2500 attendees gathered at the Moscone Center for this year's Molecular Medicine Tri-Conference, one of the flagship events in the CHI calendar. They heard a fine array of speakers on topics ranging from clinical research in Asia to pathway modeling and molecular diagnostics.
Many of the major presentations focused on personalized medicine. The opening act was a superb lecture from Harvard Business School's Clayton Christensen on disruptive technologies in health care and personalized medicine.
Name almost any industry and Christensen cited the disruptive arrival new technologies brought about by innovation — from computers and cars to music and photography. In the early days of word processing, "the Intel 286 [chip] couldn't match the pace of typing," he joked. "Now, with the Pentium 4, most mainstream applications can't use that power."
The pace of progress is mostly incremental, but is punctuated by dramatic technological breakthroughs, such as the advent of CAT scans, MRI, and PET in imaging. Often the incumbents win — for example, GE, Siemens, and Philips continue to lead the imaging field. But when disruptive innovation is affordable and simple, the entrants nearly always win, said Christensen. The rapid demise of Digital Equipment is a case in point.
The impact of disruptive technologies is no less profound in health care, molecular medicine, and imaging, said Christensen. The advent of "molecular diagnostics enables precision medicine," he said, allowing physicians to delineate conditions such as type 2 diabetes, which are in fact likely constellations of diseases presenting with a handful of common symptoms. (Christensen contrasted "precision medicine" with intuitive medicine — where much of medical practice lies still — and empirical medicine — evidence-based medicine where outcomes are probabilistic.)
Herceptin is quite predictably effective in targeting one third of breast tumors, a necessity before a truly preventative therapy can be developed, as has happened for cervical cancer.
"This will happen in next 15-20 years. The impact can be very profound," said Christensen.
Christensen sees three types of business model in health care: 1) solution shops, 2) value chains, and 3) user networks. "Hospitals will become focused solution shops practicing intuitive medicine," said Christensen. He pointed to the Mayo Clinic as an exquisite example, combining "the intuition of all relevant disciplines to see what's going on" in a patient. Focused value chain hospitals will provide procedures after a definitive diagnosis, while user networks will take the dominant role in care of chronic diseases.
In another keynote presentation, the renowned medical geneticist Tom Caskey, now CEO of the Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases in Houston, said that new indications, expanded indications, and drug safety offered three key value propositions for the diagnostics industry. The value for patients (and insurers) would include increased therapeutic response, lower costs on no response (40% of patients derive no benefit from prescribed drugs), and improved safety, which costs $50 billion, or 50 lost drugs.
Caskey reviewed the molecular diagnostics landscape. He said that newborns are currently screened for dozens of diseases, and there has been tremendous progress in prenatal and adult screening for infectious diseases, breast cancer, and cardiovascular disease. Recent studies have identified several new genes that influence risk of coronary artery disease, such as the PCSK9 gene, which codes for a protease that interacts with and modulates the LDL receptor. Celera, Caskey said, is pushing the concept of a Genetic Risk Score to evaluate heart disease risk and identify new risk genes.
Caskey also pointed out that BRCA1 and BRCA2 variants can pre-symptomatically determine the severity of breast cancer. The greatest benefit, he said, could be avoiding chemotherapy, yielding large health care and morbidity savings. "That would be a courageous undertaking in the United States — to not treat based on genetic testing," said Caskey.
Two decades of diagnostics developments were considered by the FDA's Steve Gutman, director of the Office of In Vitro Diagnostic Devices. As of March 2008, he said there were 58 genetic tests, 82 newborn screening tests, and several dozen for infectious diseases. This year, the Secretary's Advisory Committee on Genomics, Health and Society (SACGHS) will issue a major report on genetic testing, including regulatory oversight.
"The good news for personalized medicine," said Gutman, is that "the technology is there… the Human Genome Project is there." So is broad organizational commitment from the NIH and FDA. The bad news, however, is that biology and clinical science are complex and not always intuitive. A lack of method standards and inadequate mechanisms for data sharing are further problems on the horizon.
This article appeared in Bio-IT World Magazine.
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Despite telling my mom years ago that I would never become a knitter, I took up a pair of needles in 2009 and havent put them down since! Knitting is an outlet for my creative energy and my desire ...
Despite telling my mom years ago that I would never become a knitter, I took up a pair of needles in 2009 and havent put them down since! Knitting is an outlet for my creative energy and my desire to always be making things with my hands. My goal as a designer is to create unique knitting patterns; inspired by the beautiful, wild and rugged landscape of the Pacific Northwest--a place I loves to explore and am privileged to call home. I strives to write patterns that are easy to follow and simply enjoyable both to knit and to wear.
Keeping busy by day as a wife, mother of three and homemaker, I love to spend my evenings curled up on the couch with a cup of coffee, knitting, planning and sketching my never-ending design ideas. :)
If you have an questions about any of my patterns, would like to become a test knitter or to set up a trunk show, please feel free to contact me! Id love to help!
Brier is a chunky, casual beanie perfect for a relaxing weekend. Knit in a bulky, soft cotton, Brier works up quickly with a touch of unusual, textured lace for interest. Because of the lace pattern, this beanie is knitted flat (back and forth) in the beginning and then joined together and finished in the round after the lace panel is knit.
There are two sizes included; the larger size (21" ribbing circumference) is more slouchy and can be worn a little loose, almost like a beret. The smaller size (19" ribbing circumference) is more like a normal beanie, with just a little slouch in the back.
Billow, the yarn used for this pattern, is a thick-thin type yarn so the gauge might be different than your typical bulky yarn. Be sure to knit a gauge swatch to make sure your gauge is correct, especially if substituting a different yarn.
Pattern includes helpful photos and written and charted instructions including notes for all the stitches involved.
4st/5 rows= 1 inch in stockinette stitch
120 yards of Bulky weight

subset: commoncrawl


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Police are investigating a shooting Friday afternoon at an apartment complex on the southeast side of Oklahoma City.
Authorities said the shooting happened during an altercation at the Madison Village Apartments at 4220 SE 52nd St.
An Oklahoma City Police spokeswoman said a 16-year-old girl was taken to the OU Medical Center.
Stay with KOCO 5 News for more information on late breaking news.


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More than likely, Percy Harvin is out, if you look at the last time he started having migraines he sat out the next game. Last time, I think they lasted 7 days, so we might wanna count him out. The defense is suffering guys, I went to the star website and the following guys are hurting'
Kevin Williams bone is bruised in his knee
Pat Williams Elbow and Foot
Percy Harvin that time of the month
Ray Edwards Knee
Benny Sapp sore ankles
Here is the deal, they have 2 Dlineman injured, a rookie LB in place of EJ Henderson, plus the rookie of the year possibly in street clothes. I know where my money is going, and I looked at their history, and this team is jinxed, can't win the big games.
Copyright © 1995-


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Climate Talks Open in Bonn
31 May 2010: The Bonn Climate Change Talks began on 31 May 2010, and are scheduled to conclude on 11 June. The meeting brings together representatives from 182 countries and will include the 32nd sessions of the Subsidiary Bodies of the UNFCCC, the tenth session of the Ad Hoc Working Group on Long-term Cooperative Action under the Convention (AWG-LCA 10) and the 12th session of the Ad Hoc Working Group on Further Commitments for Annex I Parties under the Kyoto Protocol (AWG-KP 12).
The main item on the AWG-KP's agenda focuses on further commitments by Annex I parties. The AWG-KP is expected to work based on documentation prepared by the Chair to facilitate negotiations (FCCC/KP/AWG/2010/6 and Adds.1-5). The AWG-LCA's agenda focuses on preparation of an outcome to be presented to the 16th session of the Conference of the Parties (COP 16) and parties are expected to consider a new text by the Chair to facilitate negotiations (FCCC/AWGLCA/2010/6).
The Subsidiary Body for Implementation (SBI) will consider issues including national communications and reporting, the financial mechanism and capacity building. The Subsidiary Body for Scientific and Technological Advice (SBSTA) will consider, inter alia, methodological issues, technology transfer and the Nairobi Work Programme on impacts, vulnerability and adaptation to climate change.
At a press conference held on the first day of the talks, Yvo de Boer, UNFCCC Executive Secretary, noted that "The Copenhagen meeting may have postponed an outcome for at least a year, but it did not postpone the impacts of climate change." He stressed the need to "act now, or face the worst" in the face of scientific evidence. He added that there is growing consensus that COP 16 should aim to agree on "a full, operational architecture to implement effective, collective climate action."
The Bonn talks are being attended by over 4,500 participants, including government delegates, representatives from business and industry, environmental organisations and research institutions. [IISD RS Coverage] [UNFCCC Press Release]


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HOWLAND - The first time he beheld 100 yards of Marching Tigers in their glory - a total of 207 Howland High School band members stretched from goal line to goal line - senior drum major David Ottney had tears in his eyes.
They used to be 120 yards of Marching Tigers, back in the 1980s under the leadership of then-band director Jim Jackson, back in the days of the bigger bands.
Back then, they step-kicked to the tune of "If My Friends Could See Me Now," but today's song of choice is "Sweet Caroline."
Article Photos
Special to the Tribune Chronicle
The 207 members of the Howland High School Marching Band stretch from goal line to goal line — 100 yards of Marching Tigers. It's the first time since about the 1980s since the band has topped 200 members.
For a while, the numbers fell away. Stretching the field was out of the questions. But now they only need about 40 more people to achieve their goal of reviving the original 120-yard-long marching line.
"We thought we would bring back the tradition, and a lot of people are responding to it really well," high school band director Greg Rezabek said. "It's not just about the numbers, it's about quality of instruction and giving them a positive experience."
Rezabek, who is in his 13th year of teaching at the school, said this is the first time he has been instructing more than 200 students at once. But surprisingly, he has had very few issues.
"This is a great group this year. They're really here to do well. I can tell they want the band to do good," he said.
Senior drum major Emelia Sherin said everyone in band is there for one reason: to make music.
"And it's beautiful," she said. "(They're) all different, from their looks and personality, and they all mesh together to form this one cohesive unit. You would think that it would be a mess. But they're all attention and very sweet to work with," she said.
Still, a band as large as Howland's is not without its challenges.
"Logistics, things like getting them on and off the bus, the chairs ... planning. We plan a good week in advance having things here before they even step foot inside the door," Rezabek said.
He credited the success of the program to his fellow directors, Shawn Reynolds, middle school, and Tim Sharek, elementary and high school.
"I have some great directors who work at the elementary and the middle school, starting them out in the program. We would be nothing without them," he said.
Sherin agreed.
"We have three amazing band directors to work with and we've grown up with them, all of us," she said.
Junior drum major Nolan Nadler said despite the large number of people at practice, there is little to no conflict. He also said he enjoys being one of their leaders, someone they can look up to.
"When I entered high school, I personally found it difficult because I didn't have too many friends. They just kind of took me in and this love of band came about. I've tried to make sure every freshman, every new member of band has that same experience that I had," he said.
Ottney said band is one of the most welcoming groups in school.
"When you're in band, you're part of a family, whether you want to be or not. If you're an outcast, you're going to find a home in band. We'll take care of you," he said.
Sherin likened her experience in band to having 206 brothers and sisters.
"It's overwhelming but it's amazing," she said.
And on game night, when all 207 members become one as they are stretched from end zone to end zone, stepping and kicking and marching - it is truly a sight to behold.
"That is intense. That is one of the most powerful, most beautiful moments in our show. Because it really showcases how big we are, how powerful we are and how good we sound," Nadler said.
"I feel like it individualizes everyone. It gives everyone a chance to shine and have their moment. It's breathtaking, bringing this back after 30-plus years," Sherin said.
The 100 yards of Marching Tigers will make an appearance 7:30 p.m. Wednesday for Niles Band Night.


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Ladies' Lounge Shopping Extravaganza
Thursday 12.13.2012 @ 4:00pm | ImagesAZ | Community
Venue: Caepe School campus, 39905 N. Gavilan Peak Parkway, Anthem.
Ready to wine and dine and have a good time? Join Fellowship Church and Caepe School Dec. 13, 4 – 9 p.m. for Ladies' Lounge, an upscale shopping event featuring a great variety of unique items from area artisans.
Indulge in spa services, treat your soul to live music from Josh Isaac and Friends, warm up at a wine, coffee and tea bar, and enjoy a crepe bar, hosted by Elevate Coffee.
The event will be held at Fellowship/Caepe School Performing Arts Center, 39905 N. Gavilan Peak Parkway in Anthem. Tickets are $10, and include a gift bag filled with valuable event coupons. Tickets are sold at the door. Babysitting is available.


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FLINT TOWNSHIP, MI -- A portion of West Court Street is scheduled to close several hours Wednesday for cross tube installation.
The installation will take place between 7 a.m. and 3 p.m. on Court Street, between Dye Road and Grassmere Avenue, according to a news release from the Genesee County Road Commission.
Motorists are being advised to allow themselves additional time during their trips to reach their final destinations.
Anyone with questions may contact Swartz Creek Garage Foreman Jerry Winer at 810-397-0740 for more information.
Roberto can be reached by phone at 810-429-3865, by email at firstname.lastname@example.com, on Facebook at Roberto Acosta or on Twitter @racostaFJ.


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celebrity life
Not over yet: Justin Bieber wants Selena Gomez back but Disney star just can't trust him
- From: news.com.au
- November 12, 2012
- Gomez angry over pics of Bieber and model
- Bieber's friends say he wants Gomez back
- "Tentative plans" to repair relationship
SELENA Gomez broke up with Justin Bieber because she couldnt trust him, it has been claimed.
The 20-year-old Disney star ended the two-year relationship last week after Justin was said to be flirting with Victoria's Secret model Barbara Palvin, People magazine reports.
Bieber performed at the Victoria's Secret Fashion show while Palvin, 19, walked the runway for the lingerie giant on Wednesday.
The Hungarian model posted a picture of the pair backstage while she was in her dressing gown.
"Okay sooo because u guys were askin for it! with @justinbieber ! you were great tonight!" she wrote.
The following night Bieber and Palvin caught a performance of Broadway's The Lion King together.
The model was forced to ask his fans to "please calm down" after she tweeted "The Lion King" with a heart symbol in a veiled reference to the star. "He is all yours!!" she added.
Gomez published a cryptic tweet on Friday of Justin with Barbara in the background, writing simply: "..."
The couple's hectic schedules have been blamed for the break-up. A source told E! News: "Because of their crazy schedules, it was getting harder and harder to maintain a relationship."
Bieber and Gomez went public with their relationship in February 2011 after several months of speculation. However, the romance may not be over just yet.
The Mail Online reports that Bieber wants Gomez back. "It's not just over for Justin and Selena, whatever happens they have a lot to talk about," a source told the website, adding that the pair have tentative plans to meet and talk.
'Their schedules have been packed but Selena has made tentative plans to see Justin in New York before his Brooklyn concert, she hasn't decided if she'll attend yet, but she's keen to talk... and so is he.
'They're both being a bit cagey and stubborn but they're desperate to see one another.
'This isn't new for them, they often have a tumultuous relationship. We all expect them to work it out.'
TMZ says that the pair have broken up before many times and that this latest split is just another "blip".
Bieber has refused to confirm the split but on Saturday he told an interviewer: "I don't know what to say. I don't know what's going on in my life. To even assess that it doesn't make sense cause I have not made any comment."
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Comments on this story
doug b Posted at 9:05 AM November 12, 2012
Ummmm...news? These are not real people.
Harry of Nowra Posted at 9:00 AM November 12, 2012
Do we really care what children do?


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Boeing is able to secure an export license for the F-15SE "Silent
Eagle" jet, the company plans to offer it to South Korea and other
interested clients.Boeing and South Korean officials have
communicated about a possible deal over the past 12 months, but
Boeing has had to wait until the F-15SE's low-observable jet stealth
technology is evaluated.The U.S. contractor believes its
fighter jet is ideal because it's customizable and can support larger
digital cockpit displays, AESA radar, newer radar absorbent coatings,
and other features unavailable in older aircraft.The expected
price tag of the F-15SE is about $100 million, but can
changed depending on the technology and hardware installed.The
country reportedly "has
asked for information on Silent Eagle so now we've applied
for the [license] and we hope to get that before the end of the
month," said Brad Jones, Boeing F-15SE program manager, in an
interview. "As soon as the export license is provided,
then I can provide [marketing] information to a country."The
aircraft was publicly
introduced in 2009, and some military analysts believe it could
help fill a possible fighter gap. Boeing was unsure if it would
offer the F-15SE to other nations, but South Korea first asked in
late 2009 -- Boeing filed the necessary paperwork in early 2010, and
expects to receive approval to sell the aircraft.It's not
uncommon for South Korea, Japan, Britain, and other U.S. allies to
receive U.S. fighter jets in exchange for money and other forms of
compensation -- but the U.S. government must approve of any deals
before they're completed.The aircraft is a technological step ahead of U.S. jets
in use today (save for the F-22 Raptor), but still doesn't compare to the F-35
Lightning II Joint Strike Fighter (JSF) from Lockheed Martin.
quote: "Despite the recognition that the IAF needs the new stealth fighter to maintain its qualitative edge within the Middle East, Israel has sofar delayed its decision due to a number of reservations by the Air Force, regarding the aircraft operational range, payload and avionic suite. Through all its recent aircraft acquisitions, Israel insisted including a comprehensive array of electronic systems, primarily electronic warfare suits, command, control and communications, as well as specific weapons operated by the IAF, that provided the Israeli variants of such fighters a qualitative edge over similar types operated by Egypt, Jordan or Saudi-Arabia. These systems also provided the new fighters to be fully integrated within the Israeli command and control system, optimally operate under all conditions, and be prepared to employ indigenously developed weaponry, such as the Spice EO standoff guided weapon or Delilah loitering missiles, which have to be individually integrated into the operating systems of IAF fighters."


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In a tournament featuring some of the best high school baseball programs in California, the Valencia Vikings were determined not to open with a loss.
Avoiding defeat in its first game of the 2013 California Classic Elite Tournament, the Vikings battled back from an early deficit to tie the Archbishop Mitty Monarchs of San Jose 5-5 Friday at Valencia High School.
Valencia trailed 5-1 heading into the bottom of the sixth, before batting through the order and scoring four runs in the frame to even the game.
"We did a great job competing and never gave in," said Valencia head coach Jared Snyder. "Our relief pitching did a fantastic job. But give their starter all the credit. He was just outstanding. He's one of the best we've seen (this summer)."
Monarchs starting pitcher Kris Bubic pitched well and kept the Viking hitters off balance as he allowed just one hit with four strikeouts over four innings of work.
His only mistake came in the second inning as Valencia's Anthony Lepre hit the first pitch over the center-field fence for a solo home run to make the score 4-1.
"I was just looking for a pitch I could handle," Lepre said. "It was a fastball down the middle, and I wanted to keep my hands inside and give it a nice easy swing."
Following the home run, Archbishop Mitty responded with a run in the top of the third to make the score 5-1.
From that point, Valencia turned Jacob Smith and Chris McCready out of the bullpen, who combined to pitch four consecutive scoreless innings.
Smith recorded three strikeouts in his three innings of work, before turning the ball over to McCready for the seventh.
"(Smith) has been up and down this summer, but we're working on finding a consistent role for him," Snyder said. "Once we get that, he'll be a force for us from the left side."
However, Valencia still needed the bats to come alive.
Highlighted by a two-RBI single by Lepre to drive in Jake Silva and Keston Hiura, the Vikings proceeded to tally four runs on three hits in the inning to tie the game at five.
"He's our best hitter for a reason," Snyder said. "(Lepre) has had some great approaches, and he doesn't fear any situation."
In its first year of existence, the CCET features some of California's perennial baseball powerhouses including Harvard-Westlake (Studio City) and De La Salle (Concord).
Archbishop Mitty earned a Division I CIF Central Coast quarterfinals appearance in 2013.
Valencia will be in action again today against Elk Grove, the 2013 CIF Sac-Joaquin Section Division I champion, at 10 a.m. and Bellarmine at 2 p.m.
"This tournament is allowing us to play and compete against some great programs," Snyder said. "Teams like these put us in situations where we have to be perfect, which is exactly what we'll see come playoff time."


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Florida Championship Wrestling 89
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Learning to break kayfabe
Join Date: Aug 2012
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Re: Florida Championship Wrestling 89
Show #1, first week of March, 60 minutes
Prior to the opening, one minute of footage from last Saturday nights arena show in Miami. Dusty Rhodes, two weeks after his FCW debut, knocks off the Big Steel Man in a cage match to win the FCW title. Among those going into the cage to congratulate Dusty are Blackjack Mulligan, Dick Slater, Wahoo McDaniel and even longtime rival Harley Race who gives Dusty a surprising handshake but also a long stare. Conspicuous by his absence is Barry Windham, who Dusty had feuded with the previous year in WCW and is one of the league's biggest stars since its January start-up.
Opening one-minute theme and footage includes the song Flirtin with Disaster by southern rock band Molly Hatchet, scenes from around Florida-beaches, swamps, cities, small towns-and quick highlights from the promotions top stars including recently added footage of Dusty Rhodes.
Long time announcer Gordon Solie welcomes everyone to another exciting edition of Florida Championship Wrestling from the Sportatorium in Tampa (actually a studio, around 150 in attendance despite being packed). Gordon reminds everyone how the league has been growing and growing since starting up in January and will only be better now. Solie briefly tells about the big title change last week in Miami in front of 15,000 fans then gives the rundown on the stars on this weeks show: Barry Windham, Bad News Allan, Tyree Pride and Cactus Jack Manson plus the main event of the Fantastics vs. Terry and Dory Funk for the FCW tag titles. He also brings in color commentator Eddie Gilbert, the Florida heavyweight champion (and also a member of the booking team).
Opening match, Barry Windham vs. Tony Anthony.
Anthony comes out to the theme of Dirty White Boy by Foreigner to a round of boos, Windhams fan reaction nearly blows the roof off the studio. Windham has a large bandage on his forehead. Anthony is seconded by Black Bart, as he, Bart and Ron Bass are currently allied.
Windham starts out strong, out brawling the rugged Anthony. Gilbert picks up immediately how aggressive Windham is being. Gordon remarks how Windham knows it will take that kind of style to put Anthony down but Gilbert says it looks like something has made Windham mad.
Windham even goes outside the ring to knock out Bart before he can even think of interfering. He catches a dazed Anthony with the running lariat, winning a surprising squash in only 1:45 seconds.
Windham stops at the podium to talk to Gordon Solie and has barely worked up a sweat. Gordon asks Windham about the excitement over Dusty Rhodes returning to Florida and winning the FCW title and Windham doesnt care too much about it. He sarcastically says someone getting a title shot after two weeks, yeah thats a great accomplishment, when others have been in the new league for months. Gordon doesnt know how to respond to that one while Gilbert chuckles and understands the reason for Windhams anger.
Commercial break
Back from the commercial, and before the next match Gilbert says its time for the world debut of his video with Hot Stuff Inc, with current members Eddie and Doug Gilbert, Lou and Al Perez. The 90 second video with music of Warrants Cherry Pie features the group barhopping and at the beaches, talking with the ladies. Gordon says thats 90 seconds he will never get back and the fans arent impressed either, giving Gilbert their boos. Gilbert says they dont have these kind of women in the video in Georgia, a dig at WCW where he briefly appeared previously after WCW bought out the UWF.
Next match, its Bad News Allan (AKA Bad News Brown during his WWF run) vs. Englishman Scott McGhee, who Gordon says had a good run in Florida in the mid part of the decade. McGhee and Allan both come to the ring without music. McGhee gets good applause and Allan is mostly booed but gets a few cheers from males who like his rough no-nonsense style.
Evenly fought match as Allans brawling and martial arts are countered by McGhees quickness and scientific skills. McGhee makes a late mistake, missing Allan while attempting a dropkick off the second rope and Allans kick to the back of the head finishes it in 8:00. Allan, while still booed, gets even more cheers than during his entrance.
Allan makes his way to the podium and Gilbert offers him a hand, Allan slaps it away to Gilberts surprise. Watch it, Gilbert advises and Allan just answers anytime youre ready. Gordon starts to talk about the match when out comes Sir Oliver Humperdink, who had been out watching Allans matches the last few weeks. He is holding what appears to be a contract.
Bad News, my boy, I mean my friend, Sir Oliver begins, catching his own "boy" comment. I know youve had time to think it over and now heres my final offer, I take 75 percent but when I get you the gold youre gonna be making twice what you are now!
Allan asks Sir Oliver if he thinks he stupid, Oliver thinks for a second then answers no of course not but being his manager would help them both out. Allan says he needs nobodys help to win the FCW title and slaps the contract out of Olivers hand, then slaps Oliver across the face after being told hes an idiot. Out come Olivers men-Bam Bam Bigelow, Big Steel Man and Kareem Muhammad who do a number on Allan, kicking him and beating him, splashing him in the ring and finishing with Bam Bam s top rope head butt. Preliminary wrestlers come in to try and help as Allan has no friends among the stars and theyre all dealt with quickly too. Finally the group leaves as Allan is helped to the back, and Gilbert remarks how Allan must not have been ready as we go to commercial.
Back from commercial, and Gordon says were now about to have an interview with one of the top young stars but out comes Dusty Rhodes instead. Again the Sportatorium explodes. Dusty is at his best, jiving and talking about his love for Florida and the fans and how he is proud to win the belt. FCW president Buddy Colt comes out to the podium and announces since the FCW title will be defended in the U.S., in Mexico, in South America and in the Orient, he is elevating the title to World title status. The fans go wild, Gordon is excited, Dusty is excited despite being reminded of Big Steel Man, Harley Race and others who will want the belt, and Gilbert says he knows somebody in particular who wont like this at all.
Next match, television champion Tyree Pride vs. Mark Starr. Face vs. Face match as the two speedy competitors give the fans a great match. Both show their high flying skills and Pride wins with a cross body block off the top rope and the men shake hands after. 5:30 seconds.
Back at the podium, Gilbert starts to talk about his Florida title win recently over Dick Slater, forgetting to mention how interference from his brother and the Perez brothers helped, of course. Gordon brings it up and Gilbert tells him the video must have been edited. Interrupting is Missy Hyatts, Gilberts wife. Gilbert asks what she is doing back from vacation in the Caribbean as she had another week, and she says she missed Gilbert but she saw the video with all the womanizing. Gilbert says that wasnt really him, that was an actor and Missy believes it to Gordons amazement. Gordon can only shake his head and smile as he goes to the break. "Well, what can you say? We'll be right back."
Next match as were back, Cactus Jack Manson, seconded by Kevin Sullivan vs. Rick Diamond. Diamond has already been roughed up this hour by Humperdinks men, trying to help Bad News Allan, Gordon reminds us, and Gilbert says its about to get worse. Hes right, as Manson kicks, punches, gouges, eye rakes and beats the youngster all over the Sportatorium. Kevin Sullivan also gets in his licks while referee Bill Alfonso is distracted. Jack finally puts away Diamond, after a running knee into the corner, while Diamond is in the upside down tree of woe position. 4:30 match
To the podium are Sullivan, Manson, Buzz Sawyer and Mark Lewis. Abdullah is out on a quest, Sullivan says, and Gordon says he does not want to know. The three flunkies pace, bark and are just wild as Sullivan gleefully carries on about Dusty Rhodes being back in Florida. Gordon and Gilbert are surprised but Sullivan says this is the chance to finish him permanently as he wasnt allowed to touch him the last couple of years but maybe they can collect an eye (another inside reference to WCW, which fired Dusty after a confrontation with the Road Warriors was judged too violent, spike to the eye). The crew finally head on and Gordon immediately gets to the next match, TV time remaining, the Fantastics vs. the Funks.
Next match, the Fantastics vs. the Funks. Gordon lets everyone know just as Dustys title was elevated to world status, so was the Funks tag belts. About five minutes left in the broadcast so the action is quick from the outset. The Fantastics bedazzle the Funks with their quickness and quick tags before Dory pulls down the rope and Tommy Rogers flies over the top, with Terry distracting the ref.Crowd is extremely hot over this and Terry taunts them.
Double team brawling by the Funks with Bobby Fulton only making it worse, trying to get in and the referee having to stop him. Gilbert remarks how the bleach in his hair made him dumber than he already was, getting some criticism from Gordon. More rule breaking including the branding iron to the gut and Fulton has had enough. He throws Alfonso aside and leaps into the Funks, giving Rogers time to recover and a wild brawl ensues. Gilbert gives the Fantastics their due, saying hes seen them brawl with the best of them including some from New Zealand before they became cartoon characters (a Sheepherders/Bushwhackers reference) and the Fantastics are getting the best of the Funks as the action goes to the back. 4:30, no contest
A cameraman follows the four to the back and things are finally in control but he hears an argument and points the camera that direction. Its Barry Windham, arguing with his father Blackjack Mulligan and brother Kendall Windham. Barry says he was back in the locker room getting stitches from his match with Ron Bass during the celebration. Mulligan is heard to tell Barry youll get your chance and Barry says its gonna be the same way it was, before they see the cameraman and slam the locker room door shut. Show ends on that note.
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Action for the vulnerable in Kyrgyzstan
21 January 2009
Youth NGOs League of Volunteers and Atuul together with Agenet Network put on a fundraising concert with famous Kyrgyz singers, bands, dancing groups and volunteers themselves.
From the raised funds, the volunteers would like to purchase and distribute some heating utilities and coal for elderly people in Bishkek to combine the celebration of IVD and keep in mind the volunteers' mission is to make contribution to social development.
Public Charity Fund Babushka Adoption also held its annual Christmas Fundraising Party with a Latino flavour, Noche Latino. The evening was accompanied by Kyrgyz singers, dancers, lottery prize draw and dancing with Latino sound.
The funds raised from the evening will go towards support of Babushka Adoption beneficiaries.


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Why settle for dull when you can have delicious?
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SAW Review
Fans of the hugely successful and seemingly never-ending film series are the only people likely get some thrills out of this hit and miss horror game.
Saw the video game is really unnerving at times. Trying to escape a hideous torture device before time runs out and your head is ripped apart is incredibly unpleasant. More than any other horror game I've played this year, Saw gets under your skin. That's clearly something the development team at Zombie Studios should be proud of, but they most definitely shouldn't be congratulated for a shockingly poor combat system and a clear lack of ideas beyond the clever opening scenes.
Konami's game follows the plight of lead character Detective Tapp (Danny Glover's character in the first movie). He's been kidnapped by series villain Jigsaw, placed in a run-down asylum with loads of other people, and made to play a series of "games". Far from being Snakes and Ladders and the like, these devilish contraptions are designed to test what Tapp will do to save people linked to his past. Jigsaw, voiced superbly by the movie series' star Tobin Bell, is always on hand to relay some vital info and give moral-laden speeches via the many TVs scattered about, making the experience feel all the more authentic.
As you move from one trap to the next you'll frequently have to find keys and other items that are needed to progress. These are never just sat around on a desk, but hidden inside a vat of acid or in a toilet bowl filled with used needles. While unpleasant at first, these situations are used too often and lose their impact. Frequent electrical puzzles, in which you have to link up wires, are also used too often, which is especially annoying as they aren't entertaining the first time you have to solve one.
The same is true of the visual puzzles that crop up all over the place. Right at the start of the game there are some mirrored numbers scrawled on a wall in blood. By lining up what's written on the mirror on the other side of the room with what's visible in the reflection, you're given the combination for the lock that's keeping you inside the room. This looking in a mirror technique and slight variations on that are used throughout the game, making what was a seemingly clever idea rather predictable.
When you get to the grander traps, which usually involve Tapp and another character, the level of originality increases, but by the end of the six chapters it's still all rather samey. Many of the inventions you'll see will be familiar to fans of the movies, and they're suitably sick and twisted to fit in with the tone of the films. I won't spoil them, as fans will likely find these to be one of the game's only saving graces. It's refreshing to play a game that does challenge you from time to time with its puzzles and creates a genuine sense of impending doom as the ticking clock counts down to death.


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Grimmer rocks Darrington graduation
DARRINGTON The Darrington High School senior graduating class was treated to a rendition of Don McLeans famous Miss American Pie song by salutatorian Jordan Grimmer during its June 10 graduation ceremony.
After principal David Homer and a school board member congratulated the class, Grimmer took center stage with his guitar. Grimmer inserted his own words that specifically related to growing up in Darrington and gave the graduates plenty to laugh and smile about. As he wrapped up the song, Grimmer received a standing ovation from the capacity crowd packed into the Darrington Community Center Gymnasium.
Guest speaker Curt Simmons, author of Small Town Heroes, also talked about the uniqueness of growing up in a rural setting. He stated that, As graduates of Darrington High School, you do not need what the world has to offer. But the world needs what you have to offer. I think you will find as you go out in life that you wont encounter anything out there that is any better than what you have here in Darrington.
Following Grimmers song and Simmons speech, valedictorian Jillian Frable spoke about the promise of great things for Darringtons youth. She encouraged her classmates and stated that, I see success in every single one of my fellow graduates. She then quoted the famous expression, Watch your thoughts, they become your words. Watch your words, they become your actions. Watch your actions, they become your habits. Watch your habits, they become your character. Watch your character, for it becomes your destiny.
After the student speakers, math teacher David Heaton-Bush addressed the graduating class. Heaton-Bush told students to explore their futures as much as possible, not being afraid of change or discovery. He talked about passionately going after what they wanted as individuals and not being deterred by anything life throws in their way.
Five Darrington seniors received scholarship awards including:
Heather Burns, Bel Rea Institute
Jill Frable, WWU Bellingham
Andy Olson, WWU Bellingham
Kristen Sherman, Paul Mitchell Hair Academy
Kristi Turner, Stilly Valley CC, Mount Vernon
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Vt to dismiss charges against man shot by police
BURLINGTON Vermont prosecutors say theyre going to dismiss assault charges filed against a mentally ill man who was shot and wounded by police during a struggle.
A psychiatrist says the defendant, 35-year-old Isaac Sage, of Winooski, suffers from paranoid schizophrenia and that he was insane during the alleged assaults and is incompetent to stand trial.
The Burlington Free Press quoted Chittenden County States Attorney T.J. Donovan as saying after a Friday status conference that his office intended to drop the charges against Sage.
Sage pleaded not guilty last month to two counts of aggravated assault on a law enforcement officer and other charges.
Sage was shot in the leg April 25 after shocks from a stun gun failed to subdue him. He spent three days in jail before being hospitalized.MORE IN Vermont NewsMONTPELIER More than 2,000 young adults might have wrongly stayed on the states health... Full StoryMONTPELIER More than 2,000 young adults might have wrongly stayed on the states health... Full StoryIf this hasnt been the worst year ever for truth in politics, I cant think of what was. Full Story
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Time left to call 00 : 00 : 00
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Parodies and lawsuits
470pages on
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this wiki
Parodies and lawsuits
Barbie has frequently been the target of parody:
- In 1993 a group calling itself the "Barbie Liberation Organization" secretly modified a group of Barbie dolls by implanting voice boxes from G.I. Joe dolls, then returning the Barbies to the toy stores from where they were purchased.[37][38]
- Malibu Stacy from The Simpsons episode "Lisa vs. Malibu Stacy".
- Aqua's song "Barbie Girl" was the subject of a lawsuit by Mattel.[39][40]
- Two commercials by automobile company Nissan featuring dolls similar to Barbie and Ken was the subject of another lawsuit in 1997. In the first commercial, a female doll is lured into a car by a doll resembling GI Joe to the dismay of a Ken-like doll, accompanied by Van Halen's You Really Got Me.[41] In the second commercial, the "Barbie" doll is saved by the "G.I. Joe" doll after she is accidentally knocked into a swimming pool by the "Ken" doll to Kiss's "Dr. Love".[42] The makers of the commercial said that the dolls' names were Roxanne, Nick, and Tad. Mattel claimed that the commercial did "irreparable damage" to its products,[43][44]but settled.[45]
- Saturday Night Live aired a parody of the Barbie commercials featuring "Gangsta Bitch Barbie" and "Tupac Ken".[46] In 2002, the show also aired a skit, which starred Britney Spears as Barbie's sister Skipper.[47]
- The Tonight Show with Jay Leno displayed a "Barbie Crystal Meth Lab".[citation needed]
- Mattel sued artist Tom Forsythe over a series of photographs called Food Chain Barbie in which Barbie winds up in a blender.[48][49][50]
- In November 2002 a New York judge refused an injunction against the British-based artist Susanne Pitt, who had produced a "Dungeon Barbie" doll in bondage clothing.[51]
- Mattel filed a lawsuit in 2004 against Barbara Anderson-Walley over her website www.barbiesshop.com, which sells fetish clothing.


text:
I have a domain in mind and want to register it with ICANN. However,
I understand places like godaddy will actually write the agreement to
the effect that godaddy owns it and I just lease it. I want to own
it. Please tell me how I can do this? I am starting from nothing
more than a name right now.


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MERK in brief
Hands reaching across borders – Along this theme, the European Mennonite Regional Conference MERK 2012, which is taking place 17-20 May at Forum Sumiswald, aims to take a hopeful stand against segregation and exclusion, countering the destructive mainstream of our societies and following the teachings and example of Jesus Christ.
Between 500 and 1000 participants from various European countries are expected to attend. MERK takes place every six years, and serves as a platform for an exchange of ideas and experiences. It is an opportunity for European Mennonites to meet and become mutually inspired and encouraged.
The Swiss Mennonite Conference is responsible for MERK 2012. The organisation and programming was carried out by volunteer ad hoc committees, under the leadership of Markus Rediger, Münsingen. The programming committee is an international body.


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Research has shown that having or not having a search button makes no difference to pro users. However, for novice users, right search buttons are generally slow and inefficient. To me, the solution is simple. A left search button reduces visual fixations, puts the label first and makes doing searches faster for users.
We've all wondered why top aligned labels perform better. This article explains and illustrates why. What has your experience been?
Read the article: Why Users Fill Out Forms Faster With Top Aligned Labels


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A couple of wide releases come to the apparent end of surprisingly short Portland theater runs today. Perhaps because of some obscure ordinance mandating a maximum of one Catherine Zeta-Jones performance at a time on Rose City screens, "Broken City" is apparently beyond repair. Merely three weeks after opening, tonight's screenings of the Mark Wahlberg-Russell Crowe vehicle appear to be the last. (Zeta-Jones will be visible, though, in "Side Effects," opening tomorrow.)
"This is 40" lasted twice as long in theaters as "Broken City," but both the reviews and the box-office haul of Judd Apatow's latest film felt underwhelming. Though it wouldn't be surprising if a theater-pub picked it up in the near future, today's showings at Lloyd Mall and Clackamas Town Center are the last publicly announced ones. The DVD and Blu-ray, probably featuring an even longer cut of the film, have a scheduled release date of March 22.
And, last but not least, it seems the Rasputin-level resiliency shown by the highly entertaining dark comedy "Seven Psychopaths" has run out. The single screening at the Laurelhurst Theater tonight is your last chance to see it on the big screen for now. (Pssst...it came out on home video last week.)


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New details in a controversial case tonight as a family continues to push for justice in a police shooting that killed an Iraq War Vet, suffering from PTSD
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undies = not only underwear, but slips you wear under specifically under bridesmaid dresses
wow, thanks sarah for giving me the advice on the undies for the bridesmaid dresses. your a lifesaver.
ayon kay dersamuelmoore ika-25 ng Disyembre, 2009
Trending Now
Can you define these popular missing words?
Top Definition
The undergarments warn by both males and females.
I want you to do something for me..take of your undies and send them to me by express mail so I can get a sniff of what you smell like.
ayon kay basketcase_101 ika-14 ng Hunyo, 2003
in deaf culture, the word "understand" is shortened for quick communication.
What do you mean? I don't undy.
ayon kay "Norma Rae" ika-26 ng Hulyo, 2009
oh undies if they get too dirty flip them inside out and they are good for another week!!!
dudei've worn my undies for two weeks straight ithink i better change them!!
ayon kay jojo g. ika-08 ng Oktubre, 2006
High school underclassmen (especially freshmen and sophomores).
I got shoved by an undie in the hallway today so I schooled 'im!
The undies in my photography class thought I was a freshman -_-
The undies in my photography class thought I was a freshman -_-
ayon kay Ello the band geek ika-18 ng Disyembre, 2009
underwear, especially women's underware
Her undies were clearly stained.
ayon kay Light Joker ika-24 ng Hulyo, 2005
The undercover law enforcement
Guy 1: who's that creeping
Guy 2: its the undies bro hide the loud
Guy 2: its the undies bro hide the loud
ayon kay Youngtadoe ika-30 ng Mayo, 2016
Cock(colloqial word in malayalam)
she sucked my undy till i cummed in her mouth
ayon kay Varghese ika-09 ng Oktubre, 2007


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For those who believe America is in decline, that our economy is about to crash and our standards of living to plunge, I have just two words: lawn tractors.
And for those who say we Americans have lost our work ethic, I have one: listen. Chances are that when you go home tonight are work every evening, you hear lawn mowers and tractors roaring in your neighborhood. And today, a day of rest, a short stroll is likely to reveal several folks down on their hands and knees, sweating profusely as they attempt to get some plants to grow and others to die.
Now that's a work ethic.
Back to our economy: Each year, Americans spend about $2.5 billion on riding lawn tractors and similar equipment. We shell out another $2.7 billion for non-riding mowers and other lawn and garden equipment, and another $750 million or so for attachments. That's nearly $6 billion a year - more than the gross domestic products of about 40 countries (Haiti's GDP, at about $7.4 billion, is just slightly more than what we in the U.S. spend to cut the grass).
And that's just what we pay every year to buy equipment to maintain our lawns and gardens. It doesn't count plants, seeds, chemicals, etc. Just one firm involved in the business, the Scotts Miracle- Gro Co., reported net sales of $2.8 billion last year (and a gross profit, interestingly enough, of more than $1 billion).
Really smart young people understand the big bucks aren't in computer software. They're in front yards.
A couple of years ago, without thinking, I took a young neighborhood lad up on his offer to mow my lawn. When he'd finished, after about an hour and a half, I asked him how much I owed.
Fifty bucks. Not a bad hourly rate.
One young man of my acquaintance paid for his last two years of college by mowing grass during the summers. That's all he did during June, July and most of August, and he made lots of money.
So, no, we Americans are still doing all right, at least in comparison to billions of people in the world.
At least when our Social Security system goes bankrupt, we'll still be able to brag about our Kentucky Bluegrass.
- Myer can be reached at: firstname.lastname@example.com.


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Tag: hazard
When what can go wrong does
Here's a scenario that — even before I saw this frightening video — has flashed through my mind often since I became a dog walker.
As a natural-born worrier (I suspect it's in my genes), I'm prone to assessing the situation I'm in — even when it's an entirely pleasant one — and picturing the worst thing that could possibly happen, no matter how unlikely it is.
After six decades, I still haven't totally gotten over my fear of being sucked under the escalator grate as the step I'm standing on flattens out and disappears.
In my dog walking job, I visit three small dogs at an assisted living center, take them down the elevator, out for a walk, and then back up the elevator to their masters' rooms.
The possibility of this happening, or something like it, popped into my head my first day.
What if, as the elevator doors closed, a dog darted out, ending up on the opposite side as the elevator went down?
I've kept a firm grip on the retractable leash — and kept it in the locked position — ever since having that mental image. After seeing this video, I'll keep an even firmer one.
Tamara Seibert, a college student in Toronto was riding the elevator March 2 with two dogs — hers and a friends. They were heading from her condo unit down to the parking garage. As the doors closed, the end of her dog's leash was caught outside the elevator.
Vado, her five-year-old, 110-pound Rottweiler, was violently jerked upward as the elevator descended, and Seibert struggled to remove his collar, breaking two fingers in the process, she told the Toronto Sun.
"I thought I was going to watch him die," Seibert said.
Thankfully, the clasp on Vado's leash snapped under pressure, and he fell to the floor about the same time the elevator came to a stop and the doors opened. Thankfully too, Vado's prong-type collar had been put on with the prongs on the outside.
Seibert, a student at Ryerson University, obtained video from the surveillance camera and posted it on her Facebook page as a warning to others.
It was reposted to YouTube, where it's drawing all sorts of insensitive comments from people who would rather get in a good jab than learn something from someone else's experience.
Painful as it is to watch, it's a teachable moment, and one that proves not all my unnatural fears are that unnatural.
I, for one, have become even more cautious on the elevator, and I'm contemplating switching to the stairs — especially if I'm ever taking two dogs with me at once.
As for Vado, he's fine.
"I can't believe its been almost a month since I went through one of the most traumatic experiences of my life," Seibert wrote in a Facebook post. "I thought I was about to lose the love of my life (my puppy) and seriously mangled my hand in the process … I want to warn people how fast something so simple can go horribly wrong."
Posted by John Woestendiek March 28th, 2014 under Muttsblog, videos.
Tags: animals, canada, caution, danger, dog, dog on elevator, dogs, elevator, elevator dog, elevators, facebook, hazard, leashes, pets, rottweiler, tamara seibert, toronto, vado, video, warning, youtube
Comments: 2
Human poop poses problem for Berlin dogs
The health hazards that unscooped dog waste in public places can pose to humans has been well-established, well-documented and well-hollered-about.
So — yucky as it is — it's only right to share some news that shows the reverse side of the equation can be true, too.
According to a report from the German newspaper Tagesspiegel, dogs in Berlin are being sickened by human feces left in some public parks frequented by drug users.
Veterinarians say they've seen an increase in such poisonings.
Dogs who ingest the waste show symptoms that include shaking, dehydration and difficulty walking. Tests on dogs have found heroin and other illegal drugs present in their systems.
Vets say most cases took place in parks the city's Treptow and Kreuzberg areas, where drug users are known to gather, especially at night.
Berlin-based veterinarian Reinhold Sassnau told Tagesspiegel that the poisonings are rarely fatal. Most dogs recover if they quickly receive treatment, which includes inducing vomiting. Otherwise, prolonged treatment might be required.
Just something to keep in mind next time you (or your dog) step in a pile of dog poop (or is it?) at the park.
Posted by John Woestendiek October 24th, 2013 under Muttsblog.
Tags: addicts, berlin, defecation, dog, dog poop, drug, environment, feces, germany, hazard, health, heroin, human, human poop, ingesting, parks, poop, public, toilets, users, waste
Comments: none
Is new Chevrolet ad pawlitically incorrect?
Remember the old Chevrolet commercial — baseball, hot dogs, apple pie and Chevrolet?
Well, decades later, the car company has, for the sake of selling motor vehicles, gotten around to acknowledging another piece of Americana — the dog; specifically, the dog in the pickup truck; more specifically, the dog in a Chevrolet pickup.
And that, they will find out as the new ad airs, if they haven't yet, is some tricky ground.
It's one of those topics that raises the hackles of animal welfare activists, some of whom who say under no conditions should a dog be riding in the bed of a pickup , some of whom say it's acceptable if the dog is crated or restrained, all of whom say riding in the cab would be preferable.
And they are right. For safety's sake, it probably would be.
Last week, in "Travels with Ace," the continuing saga of the trip Ace and I are taking across America, we showed you Jake, a golden retriever in Oregon still sporting injuries he received when he tumbled out the back of a moving pickup. We did so without casting judgments or getting preachy, because our road trip is not about how dogs should live in America, only about how they do live in America.
In much of rural America, dogs are still dogs. They roam their property, and perhaps that of other's, at their will. They chase and sometimes kill wildlife. Some even live, gasp, outside. And they ride in the back of pickups, which virtually all animal welfare organizations will tell you is a bad idea.
The Chevy ad, to its credit, doesn't show any dogs in the beds of moving pickups, but, even so, I'm predicting it will lead to some lively debate if it airs widely.
On YouTube, it has already started — through Internet comments, gracious and civil as always.
"Cute video, but I wish Chevy wouldn't advocate the dogs in the back unless in a crate. Since I have seen a dog fly out of the back of a truck on a busy highway, I am traumatized for life. It should be illegal and is some places for your dog to ride loose in the bed of your truck unless you are on your own dirt road on your property with no other cars around and are willing to pay the vet bill if your dog falls out…"
"If I thought for a second my dog would ever jump out, he wouldn't ride back there. And he doesn't on the interstate. But on going into town, on rural country roads, and on my ranch, he will always ride in the back and he wouldn' t have it any other way. MIND YOUR OWN F***ING BUSINESS FAG…"
"Greatest commercial! Too bad liberal know it all's have created laws against dogs riding in truck beds! Apparently (like most libs) they know what's best for us, and will make laws accordingly. My dog will ride in the back forever though, they can suck his hairy nuts…"
Besides reflecting how crass anonymous internet banter can get — how Internet commenting has replaced the punching bag as man's default mode of venting hostilities — the discourse shows the cultural divide that exists in this country, one that's not so much conservative versus liberal as it is rural America versus the rest.
It's a generalization, but many denizens of rural America don't want the rest of America making rules that govern their access to firearms, or how they raise their dogs — from whether they spay and neuter to letting them ride in the back of pickups.
There's something to be said for letting a dog being a dog — as opposed to spending life on a leash or in a handbag — but is putting Rover in the back of a pickup letting a dog be a dog? In my view, it's courting disaster.
Yet, while many experts also advise that dogs in cars be crated or restrained, Ace is traveling acoss the country unrestrained in the back of my Jeep.
Maybe that's why I don't come down harder on dogs in pickups; maybe it's a degree of respect for rural ways; or maybe it's because the surest way to make people become more entrenched in a bad habit is to tell them they can't do it anymore.
Posted by John Woestendiek November 22nd, 2010 under Muttsblog.
Tags: accidents, advertisement, america, animals, back, bed, chevrolet, chevy, correct, culture, danger, divide, dog, dogs, hazard, injuries, jake, pawlitics, pets, pick-up, pickup, politics, riding, rural, transport, travel, traveling with dogs, truck, trucks
Comments: 2
FDA: Don't give the dog a bone, ever
Giving your dog a bone — any bone — is a dangerous practice that can cause serious injury to your pet, the Food and Drug Administration says.
It's not like they're recalling bones, but the agency has issued a warning in an article appearing on the FDA's online Consumer Updates page.
However popular the idea may be that it's natural for dogs to chew on bones, the tradition — knick-knack paddy-whack aside — falls into the danger zone, in the FDA's view.
"Some people think it's safe to give dogs large bones, like those from a ham or a roast," says Carmela Stamper, D.V.M., a veterinarian in the Center for Veterinary Medicine at the Food and Drug Administration. "Bones are unsafe no matter what their size. Giving your dog a bone may make your pet a candidate for a trip to your veterinarian's office later, possible emergency surgery, or even death."
The FDA lists 10 reasons why bones are a bad idea — and we'll pass them on verbatim:
- Broken teeth. This may call for expensive veterinary dentistry.
- Mouth or tongue injuries. These can be very bloody and messy and may require a trip to see your veterinarian.
- Bone gets looped around your dog's lower jaw. This can be frightening or painful for your dog and potentially costly to you, as it usually means a trip to see your veterinarian.
- Bone gets stuck in esophagus, the tube that food travels through to reach the stomach. Your dog may gag, trying to bring the bone back up, and will need to see your veterinarian.
- Bone gets stuck in windpipe. This may happen if your dog accidentally inhales a small enough piece of bone. This is an emergency because your dog will have trouble breathing. Get your pet to your veterinarian immediately!
- Bone gets stuck in stomach. It went down just fine, but the bone may be too big to pass out of the stomach and into the intestines. Depending on the bone's size, your dog may need surgery or upper gastrointestinal endoscopy, a procedure in which your veterinarian uses a long tube with a built-in camera and grabbing tools to try to remove the stuck bone from the stomach.
- Bone gets stuck in intestines and causes a blockage. It may be time for surgery.
- Constipation due to bone fragments. Your dog may have a hard time passing the bone fragments because they're very sharp and they scrape the inside of the large intestine or rectum as they move along. This causes severe pain and may require a visit to your veterinarian.
- Severe bleeding from the rectum. This is very messy and can be dangerous. It's time for a trip to see your veterinarian.
- Peritonitis. This nasty, difficult-to-treat bacterial infection of the abdomen is caused when bone fragments poke holes in your dog's stomach or intestines. Your dog needs an emergency visit to your veterinarian because peritonitis can kill your dog.
"Always supervise your dog with any chew product, especially one your dog hasn't had before," adds Stamper. "And always, if your dog 'just isn't acting right,' call your veterinarian right away!"
We agree with those last two points, at least, but can't help but wonder if a total bone ban may be a bit over-protective, a bit contrary to the nature and roots of dogs, and one more step in turning dogs into humans.
Most bones are bad — chicken bones, as we all know, in particular. But there are those that, with supervision, I don't hesitate to give my particular dog, like marrow bones. They can help clean teeth, massage gums and, in my dog's experience, seem quite safe.
What school are you in when it comes to bones? Do you think some are OK? Do you ban them in your household? Do you have a bone to pick with the FDA? We'd love to hear your thoughts.
Posted by John Woestendiek April 22nd, 2010 under Muttsblog.
Tags: animals, bone, bones, caution, chew, dangerous, dog food, dogs, fda, food and drug administration, gag, hazard, health, injuries, news, obstruction, pets, safety, splinter, teeth, treats, warning
Comments: 14
FDA reviewing complaints about dog treats
Real Ham Bone for Dogs — dog treats made in Missouri from the femurs of pigs — are under review by the Food and Drug Administration after complaints of them causing serious injury and death in dogs.
If warranted, an FDA spokesman said, the FDA will take appropriate action and notify the public, the Associated Press reported.
The product — a smoked pig femur sold as a dog treat or chew bone — is distributed nationally under the Dynamic Pet Products label of Frick's Quality Meats in Washington, Mo.
The company said Thursday it was saddened to learn of the illnesses and deaths of customers' pets, and that quality and safety remain priorities. The packaging contains a warning about the product not being for all dogs, and the possibility that it could splinter."
"That is why every package contains a label that provides detailed instructions to owners on how they can help their pets best enjoy our products," the company said in a statement. "We strongly encourage owners to supervise their pets with any treats or snacks."
The Better Business Bureau of St. Louis said consumers have complained about the bones splintering, and pieces obstructing dogs' intestines. Consumers reported their dogs had become lethargic or were vomiting. One man came home to find his dog dead, bleeding from the mouth.
Posted by John Woestendiek March 12th, 2010 under Muttsblog.
Tags: alert, animals, better business bureau, bone, chew, choking, complaints, consumer, consumers, danger, death, dogs, fda, femur, food and drug administration, frick's quality meats, hazard, health, illness, investigation, missouri, news, pets, pig, real ham bone for dogs, recall, review, st. louis, treat
Comments: 2
Wieners: Best over-reactor in a dramatic roll
Does the hot dog need a makeover?
The nation's largest pediatricians group thinks so. The American Academy of Pediatrics — un-American as it may sound — is calling for sweeping changes in the way the hot dog is designed to minimize children's chances for choking.
In a policy statement issued earlier this week, the group identified the hot dog as the greatest food-related choking hazard to children, particularly those ages 3 and younger, and said the shape plays a large role in making it unsafe.
The academy proposes warning labels be placed on hot dogs, and that consideration be given to manufacturing them — gasp! — in the shape of a patty.
The academy cited statistics showing 17 percent of food-related choking deaths among children come from from hot dogs. Other common food choking hazards include grapes, apples, popcorn and nuts, the group said. Of the 141 choking deaths in kids 14 and under in 2006, 61 were food-related, according to an Associated Press story.
The doctors say high-risk foods — including hot dogs, raw carrots, grapes and apples – should be served to small children in pea-sized pieces to reduce chances of choking.
We'd agree with that much, but we think it's up to parents, as opposed to the government, to see that their childrens' food is cut into manageable pieces.
(Click here for all of the Wiener Awards.)
Posted by John Woestendiek February 25th, 2010 under Muttsblog.
Tags: american academy of pediatrics, children, choke, choking, death, dogs, food, frankfurter, hazard, health, hot dogs, news, pediatricians, redesign, reshape, safety, shape, weiner, wiener, wieners
Comments: 2
Dog sticks tongue in paper shredder
Here's a household pet hazard that — dastardly as it is — you don't hear about too often.
But first the moral of the story: If you have a pet at home, or a child for that matter, don't ever leave your paper shredder on automatic.
The owners of a mixed breed dog named Diamond found that out the hard way last week, when their 8-year-old dog licked their's, only to have her tongue pulled into the sharp blades.
"She had licked a paper shredder in the house that was set on automatic," Dr. Marc Wosar, of Miami Veterinary Specialists, told TV station WPLG.
Fortunately, Diamond's owners were home and responded quickly. They disconnected the head of the shredder, carefully taking it and the dog whose tongue it held to the animal hospital.
"We anesthetized her first, then reversed the shredder off the tongue and assessed the damage," said Wosar. "There were a lot of lacerations to the tongue as well as a lot of bite wounds. In her panic, she'd also bitten her tongue."
It took more than a 100 stitches to repair Diamond's tongue. A portion that was too severely damaged had to be removed, but doctors expect her to make a full recovery.
"She just won't have a perfectly round tongue. She'll have a little nick in it," said Wosar.
(Photo: WPLG)
Posted by John Woestendiek May 29th, 2009 under Muttsblog.
Tags: automatic, cuts, danger, diamond, dog, dogs, hazard, health, lacerations, marc wosar, miami veterinary specialists, paper shredder, pet, safety, shredder, stiches, tongue, vet, veterinarian, veterinary, warning
Comments: 1


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From IDIBELL-Hospital Universitari de Bellvitge, University of Barcelona, and SCIAS-Hospital de Barcelona, Barcelona, Spain.
Trial ISRCTN41238928.
Acknowledgments: The authors thank Ginesa Albero for data management and statistical analyses and Dr. Tom Gottlieb for his review of the manuscript. They also thank the staff members and residents of the Infectious Disease, Respiratory, Internal Medicine, and Emergency Medicine Services of the IDIBELL-Hospital Universitari de Bellvitge and the SCIAS-Hospital de Barcelona for their valuable cooperation.
Grant Support: By research grants from the Spanish National Health Service (FIS 00/0438) and from Aventis, Madrid, Spain. Dr. Fernández-Sabé is the recipient of a fellowship grant from the University of Barcelona, Barcelona, Spain.
Potential Financial Conflicts of Interest: Honoraria: J. Dorca (Aventis), F. Gudiol (Aventis); Grants received: F. Gudiol (Aventis).
Requests for Single Reprints: Jordi Carratalà, MD, Infectious Disease Service, Hospital Universitari de Bellvitge, Feixa Llarga s/n, L'Hospitalet de Llobregat, 08907 Barcelona, Spain; e-mail, email@example.com.
Current Author Addresses: Drs. Carratalà, Fernández-Sabé, Rosón, and Gudiol and Miss Fernández-Agüera: Infectious Disease Service, Hospital Universitari de Bellvitge, Feixa Llarga s/n, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Drs. Ortega and Martínez: Internal Medicine Service, SCIAS-Hospital de Barcelona, Diagonal 660, 08034 Barcelona, Spain.
Dr. Castellsagué: Cancer Epidemiology and Registration Unit, Institut Català d'Oncologia, Gran Via s/n, Km 2.7, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Drs. Dorca and Manresa: Respiratory Medicine Service, Hospital Universitari de Bellvitge, Feixa Llarga s/n, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Dr. Verdaguer: Microbiology Service, Hospital Universitari de Bellvitge, Feixa Llarga s/n, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Author Contributions: Conception and design: J. Carratalà, F. Gudiol.
Analysis and interpretation of the data: J. Carratalà, N. Fernández-Sabé, L. Ortega, X. Castellsagué, B. Rosón, J. Dorca, A. Fernández-Agüera, R. Verdaguer, J. Martínez, F. Manresa, F. Gudiol.
Drafting of the article: J. Carratalà, N. Fernández-Sabé, X. Castellsagué, F. Gudiol.
Critical revision of the article for important intellectual content: J. Carratalà, N. Fernández-Sabé, L. Ortega, X. Castellsagué, B. Rosón, J. Dorca, A. Fernández-Agüera, R. Verdaguer, J. Martínez, F. Manresa, F. Gudiol.
Final approval of the article: J. Carratalà, N. Fernández-Sabé, L. Ortega, X. Castellsagué, J. Dorca, A. Fernández-Agüera, R. Verdaguer, J. Martínez, F. Manresa, F. Gudiol.
Provision of study materials or patients: J. Carratalà, N. Fernández-Sabé, L. Ortega.
Statistical expertise: X. Castellsagué, B. Rosón.
Obtaining of funding: J. Carratalà, F. Gudiol.
Collection and assembly of data: J. Carratalà, N. Fernández-Sabé, L. Ortega, B. Rosón, J. Dorca, A. Fernández-Agüera, R. Verdaguer, J. Martínez, F. Manresa, F. Gudiol.
A total of 224 patients were randomly assigned and included in an intention-to-treat analysis for the primary end point. Of these, 110 received outpatient care and 114 were hospitalized. After excluding 21 patients after enrollment who could not be evaluated, we analyzed the remaining 203 for the primary and secondary end points per protocol. The baseline characteristics of the patients in the 2 treatment groups were similar (Table 1) and did not differ significantly by hospital site. An etiologic diagnosis was established in 37 of 103 outpatients (35.9%) and 28 of 104 hospitalized patients (26.9%) who had pneumonia. The distribution of causative organisms did not differ between groups. Streptococcus pneumoniae(22 outpatients vs. 16 hospitalized patients) and L. pneumophila(6 outpatients vs. 5 hospitalized patients) were the most frequently isolated pathogens, followed by atypical agents (4 outpatients vs. 3 hospitalized patients) and Haemophilus influenzae(3 outpatients vs. 3 hospitalized patients). Bacteremia occurred in 3 outpatients (S. pneumoniae in 2 and Escherichia coli in 1) and in 1 hospitalized patient (S. pneumoniae). Forty-one percent of S. pneumoniae isolates were penicillin-resistant (MIC range, 0.5 µg/mL to 4 µg/mL), and 35% of the strains were resistant to erythromycin (MIC >256 µg/mL for all strains). Only 1 pneumococcal strain was resistant to ceftriaxone (MIC, 2 µg/mL). All S. pneumoniae isolates were susceptible to levofloxacin (MIC range, 0.5 µg/mL to 1 µg/mL).
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As noted by Carratalà , et. al.(1), "The Pneumonia Severity Index (PSI) has been advocated as an objective measure of risk stratification to help determine the initial site of treatment for patients with community- acquired pneumonia." Unfortunately this study does little to test that hypothesis. Fully 47% of PSI class II or III patients were excluded prior to randomization because they were judged to be too sick to manage as outpatients or were otherwise not suitable for outpatient therapy. Thus this study actually tested a combined approach of using the PSI along with several additional criteria devised by the investigators.
This finding is remarkably consistent with prior studies of attempts to apply the PSI to actual decisions to treat patients with pneumonia as outpatients. Fine, et.al.(2) validated the PSI criteria in the Pneumonia Patient Outcomes Research Team (PORT) cohort. In this cohort, 24% of PSI class I patients, 49% of class II patients, and 78% of class III patients were treated initially as inpatients. Marrie, et.al.(3) studied a critical pathway that included PSI scoring for pneumonia patients. In the intervention arm, 31% of class I-III patients were admitted. In all these studies, the PSI was augmented by additional criteria of some type to determine admission criteria.
The concept of using the PSI to determine treatment decisions in an unselected population remains an untested hypothesis. Carratalà , et. al. used the PSI in a very highly selected group of already low-risk patients. It would be a mistake to conclude that this study validates use of the PSI to determine treatment decisions in other populations of patients.
(1) J. Carratalà , N. Fernández-Sabé, L. Ortega, X. Castellsagué, B. Rosón, J. Dorca, A. Fernández-Agüera, R. Verdaguer, J. MartÃnez, F. Manresa and F. Gudiol. Outpatient Care Compared with Hospitalization for Community-Acquired Pneumonia: A Randomized Trial in Low-Risk Patients. Ann Intern Med 2005; 165-172. (2) Fine, Michael J., Auble, Thomas E., Yealy, Donald M., Hanusa, Barbara H., Weissfeld, Lisa A., Singer, Daniel E., Coley, Christopher M., Marrie, Thomas J., Kapoor, Wishwa N. A Prediction Rule to Identify Low-Risk Patients with Community-Acquired Pneumonia. N Engl J Med 1997; 336: 243- 250. (3) Thomas J. Marrie; Catherine Y. Lau; Susan L. Wheeler; Cindy J. Wong; Margaret K. Vandervoort; Brian G. Feagan; for the CAPITAL Study Investigators. A Controlled Trial of a Critical Pathway for Treatment of Community-Acquired Pneumonia. JAMA 2000; 283: 749-755
None declared
Can Patients with Pneumonia Take Their Antibiotics at Home?
The summary below is from the full report titled "Outpatient Care Compared with Hospitalization for Community-Acquired Pneumonia. A Randomized Trial in Low-Risk Patients." It is in the 1 February 2005 issue of Annals of Internal Medicine (volume 142, pages 165-172). The authors are J. Carratalà, N. Fernández-Sabé, L. Ortega, X. Castellsagué, B. Rosón, J. Dorca, A. Fernández-Agüera, R. Verdaguer, J. Martínez, F. Manresa, and F. Gudiol.
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We can't handle the truth!
On the TV news and over the Internet, Mitt Romney was secretly recorded by former President Carter's grandson. Romney spoke on what he believed to be the truth about Americans and our government. When a politician speaks the truth, we Americans do not want to hear him or her. Why?
At a May 17th fundraiser in Boca Raton, Fla., Romney was heard saying, "There are 47 percent who are with him, who are dependent upon government, who believe that they are victims, who believe that government has a responsibility to care for them, who believe that they are entitled to health care, to food, to housing, to you name it."
Many people keep saying that the politicians lie and say what they think we want to hear. Along comes someone who has been in business, as well as a governor, and speaks what he believes the government is doing. In a sense making many Americans lazy. The truth is most of the citizens of this nation believe we have become just that, lazy and expecting the government to take care of us.
Romney may not have chosen the correct words to describe who and possibly why so many will vote for Obama and think he is special, but isn't our president saying what most want to hear? Do these same 47 percent of voters, who will surely vote for Obama, know where the government gets the money to dole out?
Not long ago I spoke with a young woman who goes to a local University about a student loan she received. When I mentioned that the government loan was actually from the taxpayer, she shook her head no. She was under the assumption her money came from the government only.
It makes me wonder if she, and those who receive funds from the government would be so generous if they had to pay others with their own money? How about you?
Ida M Temple
Submitted by Virtual Newsroom


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MOBILE, Alabama -- Arkansas-based Centennial Bank announced Thursday an agreement to buy 17 Vision Bank branch locations, all of its deposits and a majority of the bank's performing loans from Park National Corp.
Vision is the third-largest bank in Baldwin County by market share with $364 million in deposits -- an 11.25 percent share, according to federal data. It has eight offices in the county.
The purchase price is $27.9 million, according to a filing from Centennial's parent company, Home BancShares Inc.
Centennial will acquire $535 million in deposits and $379 million in loans as part of the agreement, which is subject to regulatory approvals and is expected to be complete in early 2012.
Vision branches will become Centennial branches once the deal is complete. Company officials said Vision customers should continue to bank as normal until then.
The move allows Centennial to increase its footprint in Florida and expand into Alabama, officials said.
"It will be a new beginning for the Vision bankers and directors, working without the burden of problem assets," said John W. Allison, chairman of Home BancShares.
Vision was heavily invested in beach properties that saw values plummet and bad loans during the real estate crisis.
It had been bleeding money for Ohio-based Park National, which owns several community banks. For example, during the first three months of 2011, Vision lost $7.6 million while Park National posted an overall profit of $21.4 million.
Vision lost $29.3 million in 2010 and $30.1 million in 2009.
Park National officials said it will keep some nonperforming loans and merge them with a non-bank subsidiary, SE Property Holdings LLC.
Park National officials said the sale will result in a pre-tax gain of $10 million to $12 million and will strengthen the company's capital ratios.
Park National acquired Panama City, Fla.-based Vision Bank in March 2007 in a deal valued at about $165 million.


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THERE are many more attractive towns and villages on the Cape's scenic west coast than Saldanha Bay. Although it is recognised as the best natural harbour along SA's coast, its landscape is scarred by a giant and ugly steel works and it is home to the Saldanha Iron Ore Terminal, a busy harbour, canneries and a military training base and academy, so it is not a natural leisure destination
However, it's on the military property that a surprise awaits in the form of the SAS Saldanha Nature Reserve, a wedge of unspoilt land protruding into the sea and creating a peaceful environment that is the antithesis of its bustling surroundings. The reserve combines interesting historical artifacts with fascinating fauna and flora in spectacular surroundings, only 90 minutes drive from Cape Town.
After travelling through the town, we reach the military academy and, once past the sports grounds and miscellaneous buildings, we arrive at a small car park and enter the reserve, making sure there is no sign of the red flag that indicates shooting practice is in progress.
Once inside, one has the choice of mountain-biking or hiking the four demarcated routes, which vary in length from 4km to 14km. The routes were once marked with different coloured stones but many of these have disappeared. However, it is not difficult to find the way and one is unlikely to get lost if following the shore and taking note of the rocky outcrops that serve as beacons.
We choose to cycle the longer route along a sandy but relatively flat track, which passes areas of historical and natural interest. Huge rocks emerge from the ground like giant mushrooms facing the fury of the waves that lash them, sending fountains of spray skywards. In the 1700s, several ships fell victim to the angry sea off North Bay. The Dutch East Indiaman Merensteijn, which was carrying a valuable consignment of silver coins, sank nearby in 1702 and only 99 of its 200 crew survived. Many of the coins were salvaged in 1971, to the delight of collectors who, due to the coins' rarity and value, rate the Merensteijn as the most important coin wreck off the South African coast.
The Middleburg also had an unhappy end when it was set ablaze here by Dutch sailors seeking to avoid capture by the English in 1781 and went down with an unknown amount of treasure on board. Here, too, in what is referred to as the Battle of Saldanha Bay, in 1796 a squadron of the Batavian Republic anchored and surrendered without a fight to a Royal Navy squadron.
The route then passes abandoned Second World War buildings. Saldanha was identified as a convoy staging point, and in 1942 coastal defence guns were set up.
The original guns can still be seen at the top of Malgaskop, which serves as accommodation for military-academy students. Magnetic loops on either side of a minefield gave early warning of submarines trying to enter the bay, and detection equipment was operated by the South African Women's Auxiliary Service in two fortified buildings near North Bay.
Levine's Cottage, originally the home of Stephen Levine, a prominent citizen and co-author of The Saldanha Bay Story, can still be seen. Below the cottage are the remains of two gunnery targets that broke their tow en route to the target area and washed up on shore.
The route then moves away from the sea and circles a salt pan to an area in which game gathers. We spot springbok, which show no interest in our presence, while ostriches seem intent on stretching their long legs at a canter. Bontebok, rhebuck and red hartebees are common, while a range of smaller animals including caracal and bat-eared fox frequent the area but are not often seen.
The trail then makes a gradual climb over the top of Môresonkop, from which point we get a good view of the general area. In the distance, the small Malgas Island is clearly visible. Occupying an area of only 8.3ha, the island is home to tens of thousands of Cape gannets, which cover the island like a white carpet. They can leave the island and may fly for 100km in search of fish — their excellent eyesight enabling them to see shoals at considerable depths. They can be seen catching fish by diving from between 15m and 25m above the sea, folding their wings in and falling like stones.
In 1845, highly prized guano was removed from the island as it was regarded as a valuable fertiliser and much was exported and sold in London at one guinea a ton.
As with much of the surrounding area, the reserve becomes alive with colour in late winter and spring, when carpets of flowers form a kaleidoscope of colour. But the area offers much to the visitor throughout the year as it forms a microcosm of the natural wonders of the west coast.
Its indigenous fynbos and animal life are typical of the west coast environment. The area boasts many varieties of vygie, which flower during winter, including the poeierkwasvygie, oranjevygie, Bokbaaivygie and Hotnotsvygie among many other tongue-twisting vygies. Flame and arum lilies are to be found throughout the year, as are a host of other unusual and interesting plants.
In spring, the reserve is also an ideal area from which to view the visiting southern right whales. The rocky outcrops along the shore provide an excellent vantage point from which to observe the whales as they breach. Similarly, birders will not have to peer through binoculars to see the gannets on Malgas Island, as they are also likely to catch sight of gulls, cormorants and duikers in the reserve.
As there are no facilities in the reserve, it is wise to carry a rucksack or bag with refreshments for the visit.