text:
Tanya (Manriquez) Lujan ('09)
When Tanya got home, she didn't immediately start her 10-page paper. Instead, she cooked dinner for her kids, helped with homework, and put them to bed. At midnight, she began sorting through stacks of research and notes, drifting off to sleep at 2:00 a.m., only to have her children wake her for breakfast at 6:00 a.m.
Tanya is a wife and mother who took a big chance to attend ACU. Because her husband had a good job in Odessa as a police officer, Tanya moved to Abilene with her children so she could complete her education in speech pathology, since there was no program available in Odessa. Over time, with weekend help from her husband and with local support from professors and friends, Tanya completed her degree.
A family's response to tragedy
Before graduation, Tanya reflected on a family who helped make her ACU experience possible. When Larry and Barbara Cobb's daughter, Audra, died in an accident while studying speech pathology at ACU, family and friends honored Audra's memory by establishing the Audra Cobb Memorial Scholarship. This departmental scholarship, along with a transfer scholarship, was critical to funding Tanya's education.
She had the opportunity to meet Mr. and Mrs. Cobb and recounted the emotional visit that ended with tears of both gratitude and joy.
ACU is more than an education. It's a Christian education that I am confident will make me into a Christian professional. Yes, this will set me apart from most, but in a very good way.
After graduation, Tanya moved back to Odessa where her husband and family were anxiously waiting. She is leaving ACU but hopes to return someday—if her nine year old son doesn't beat her to it! He has been witness to the tangible changes in his mom and looks forward to attending ACU someday.
Advice to incoming students
"If you are considering coming to ACU, don't second guess yourself. It will change your life for the better and teach you so many things you never thought possible. If you think you can't afford it, have faith, because it can happen to you. There are scholarships and financial aid. . . the point is you can go to school, and ACU is the best place to attend."
Supporting ACU means supporting students like Tanya, who depend on scholarships to receive an education here. That's why the Office of Advancement exists: to strengthen, renew and build the relationships that help fund the mission, Promise and 21st-Century Vision of ACU, thereby helping more students like Tanya experience the life-changing effects of the ACU experience.
Give Online
Help educate students for Christian service and leadership.
Refer a Student
Recommend a prospective student that would ba good fit for ACU.
Update Your Records
Moved recently? Log in to the Online Alumni Directory and update your records.Alumni Directory


text:
DALLAS - The leader of a major cocaine and marijuana smuggling ring who made more than $3 million off drug proceeds has been sentenced to life in prison without parole.
Joe Gary Rivas, 59, of San Angelo, was responsible for smuggling and distributing more than 20,000 pounds of marijuana and 264 kilograms of cocaine, U.S. District Judge Sam Cummings of Lubbock found.
He was part of a drug ring that trafficked large amounts of drugs from Mexico to the United States from 1996-2003.
U.S. Attorney Richard B. Roper said the life sentence, handed down Aug. 27, was justified.
"Rivas and his organization are finished," Roper said in a news release. "The 15 different law enforcement agencies who teamed up to bring down this organization demonstrate the commitment of West Texas law enforcement to take on large-scale narcotics trafficking."
Rivas pleaded guilty in June to conspiracy to import drugs.
© 2016. All Rights Reserved. | Contact Us

subset: commoncrawl


text:
Clinton dominates first presidential debate against a blustering Trump
Hillary Clinton and Donald Trump got down and dirty in a battling debate never quite seen before in American presidential politics. Clinton was largely viewed as the night's winner, with several analysts and news publications praising her ability to effectively slam Trump with facts and figures. The Washington Post declared Clinton occasionally came across as "overly rehearsed and robotic," but applauded her responses to Trump and her apology for the email scandal. More »International Business Times - 4 hours ago
Ryder Cup 2016: Guide to the Europe team aiming for a fourth victory in a row
The Ryder Cup, one of the truly great events in world sport, takes place at Hazeltine this week. A popular figure with fans, Clarke undoubtedly has the capabilities to inspire his team. A hugely important figure for Europe at Hazeltine, with the potential to be a talisman for his team. More »Nick Metcalfe - 9 hours ago
Ice hockey-Upstart Team Europe to face Canada in World Cup final
By Steve Keating TORONTO, Sept 26 (Reuters) - Hosts Canada, the two-time reigning Olympic champions who are deep in both tradition and talent, were always expected to reach this week's World Cup of Hockey final. What it means is a confounding but intriguing best-of-three final starting on Tuesday with hot favourites Canada taking on the longest of tournament longshots. At one end of the ice will stand Canada, the Goliath of the hockey world, while a group of Davids without a country, flag or anthem and whose coach's day job is chairman of Premiership club Southampton FC will stand at the other. More »Reuters - 12 hours ago
Son Heung-min delighted with Tottenham transfer decision
Son Heung-min is relieved Tottenham Hotspur decided against selling him during the summer transfer window following his blistering start to the season. The South Korea started the campaign playing in the Olympic Games but upon his return to White Hart Lane he has scored four times in three appearances – including a double in the Premier League win over Middlesbrough. Following an uncertain campaign since his £22m move, according to The Guardian, to north London, during which he netted just eight times in 42 outings in all competitions, Son was linked with a return to Germany with Wolfsburg. More »International Business Times - 13 hours ago
Four-time Olympic gold medalist Mo Farah reveals ambition to become Arsenal's fitness coach
Four-time Olympic gold medalist Mo Farah dreams of becoming a fitness coach at Arsenal once his athletics career is over. The 33-year-old star is a long-time supporter of the Gunners and has admitted he would love to move into the world of professional football once he hangs up his running spikes. "One thing I really love is football and I have a good relationship with Arsenal. More »International Business Times - 14 hours ago


text:
Discussion in 'Python' started by Neuruss, Aug 2, 2004.
Does anyone have news about Starkiller?
Neuruss wrote:
> Does anyone have news about Starkiller?
I met Michael Salib recently, and he said it will be available shortly
(maybe a month or two? I forget). The runtime will be BSD licensed and
the application itself will be GPL.
Robert Kern
"In the fields of hell where the grass grows high
Are the graves of dreams allowed to die."
-- Richard Harter
I sent Michael an email by the end of June, and he replied that it
would take a "a few weeks" because he was redoing some parts to make
the code more comprehendable and mantainable.
I just wonder how many weeks are "a few weeks" ;-)
He was very kind to reply, but since I don't know Michael personally,
I don't want to bother him with more questions...
Neuruss wrote:
> Does anyone have news about Starkiller?
Here's the Starkiller website:
It says hopefully it will be released by October.
Separate names with a comma.


text: Talk:Hull plating Back to page 41,436pages on this wiki Add topic edit this page History From Talk:Hull plate Edit Merge suggestion Edit Hull plate and hull plating are the exact same subject, just singular vs plural. -- Capricorn (talk) 06:22, August 1, 2015 (UTC) Support --| TrekFan Open a channel 13:51, August 1, 2015 (UTC) Merged. Tom (talk) 09:59, August 24, 2015 (UTC) Retrieved from "http://memory-alpha.wikia.com/wiki/Talk:Hull_plating?oldid=1743190"


text:
MARTINSBURG - First Friday Coffeehouse will feature Butch Ross, a dulcimer virtuoso from Chattanooga, on Friday.
The venue is located at Trinity Orchard House on W.Va. 45, four miles from the four-way stop in Shepherdstown. Doors open for social time and open sign-up at 7:30 p.m. All open mic participants should be there early to get a slot to perform two songs or eight minutes at one of the area's premier listening rooms.
Butch Ross plays the mountain dulcimer - standing up like a guitar, upside and strung backwards, and he plays rock 'n' roll on it. He even plays Led Zeppelin's "Stairway to Heaven." He also plays his own funny, poignant songs and some traditional mountain tunes - and a whole bunch of other instruments that he loops together to form a one man band.
Article Photos
Submitted photo
First Friday Coffeehouse will feature Butch Ross, a dulcimer virtuoso from Chattanooga, on Friday.
The dulcimer has earned Ross a reputation amongst the folk community as one of the most innovative and exciting players on the scene. He's opened for wide variety of performers from bluegrass comedy artists like Hayseed Dixie and folk greats like Small Potatoes, Bill Staines and Jean Ritchie. He also opened for ukulele master Jake Shimabukuro.
For more information, visit www.butchross.com.
Enjoy a great evening of music and fellowship. Snacks and refreshments served. Trinity Orchard House is located at 4599 Shepherdstown Road (W.Va. 45) in Martinsburg. From Shepherdstown, itis four miles on the right from the four-way stop, just before The Pump House.
Upcoming feature performers are will be Kevin Dudley on May 3 and Mercedes Mill on June 7.
A $10 donation per person is requested. For more information, contact Steve Warner at 304-676-4422 or 304-876-2915.


text:
Golf: Tourney winners
Mount Maunganui club members Laurel and Mike Flattery won the Pacific Coast Village 72-hole Mixed Foursomes Stanley Cup from Joshua Tamihana and Wai Wyatt from the Omanu club.
The Flattery team were previous winners of the trophy and were keen to reclaim it so they put in some hard work playing in the Rotorua Mixed Foursomes as one of their lead-up events.
There were any number of likely favourites in the division who faltered along the path - namely Pip and Owen Kendall (Mount Maunganui), Alex and Raewyn Te Moni (Ngaruawahia), Martin and Tarraleigh Te Moni (Ngaruawahia), Steve and Leslie Haggie (Cambridge), Mike and Ricky Leitch (Auckland), Geoff Winchester and Claire Davison (Mount Maunganui).
All divisions were hotly contested with many matches requiring a putt-off to decide the winner.
Highlights of the weekend (apart from the weather and the course presentation) were June and John Winstanley scoring a two on the par four seventh hole and a dead heat for Closest to the Pin between Steve Snow and Steve Haggie.
A full field of five divisions (80 pairs), 32 more than for last year's tournament, included 58 players visiting Mount Maunganui from North and South Island clubs.
Anne and Fred Matenga (regular competitors in the tournament) flew the flag for the South Island/Otago region and were challenged by the players from 26 other North Island clubs, giving a wide representation of clubs.
The 68 Mount Maunganui Golf Club members provided strong support for the tournament along with their close neighbours Omanu (24) and other local clubs.
Cricket: Title defence
Defending Fergus Hickey Rosebowl titleholders Bay of Plenty will have a double agenda on day one of the annual Northern Districts one-day tournament being played at Owen Delaney Park in Taupo from Sunday.
Success against Northland on the opening day should secure an elusive Hawke Cup challenge early next season. The Hawke Cup, which is the symbol of New Zealand Minor Cricket Association supremacy, was first contested in 1911 as a tournament trophy.
Since 1913 it has been played on a challenge basis, with the holders accepting direct challenges during February and March of each season.
To earn the right to a direct challenge, Bay of Plenty must win the ND series that is held within the Fergus Hickey Rosebowl competitions during the calendar year.
Entering the last three rounds of this year's ND Hawke Cup qualifying competition, which will also be played in Taupo, the Bay team are in the box seat. If they can beat long-time rivals Northland they will extend their lead to an unassailable position.
Defeat would still give the Bay a second shot at grabbing the qualifying place on day three. The game against current Hawke Cup holders Hamilton on the second day will count for nothing, with the final match-up with Counties Manukau assuming vital importance if they lose to Northland.
With three Fergus Hickey Rosebowls won in the past four seasons, the Bay of Plenty team have the experience and firepower to make this a vintage period in Bay of Plenty Cricket history.
There are few more wily skippers in minor association cricket in the country than Bay captain Jono Boult. In the past couple of New Zealand winters, Boult has crafted his skills playing in Holland, with previous spells spent playing in Britain.
The Bay skipper set new Bay of Plenty season bowling figures of 33 wickets last season, which broke long-time Bay servant Graeme Aldridge's figures. In addition he sits in seventh place of the Bay's all-time batting totals with 1549 runs.
Last season's top run scorer, Peter Drysdale, who smashed nearly 400 runs during the Fergus Hickey season, was another to play in the Northern Hemisphere last winter. Add in Brett Hampton (Holland), Ben Christensen (UK) and Tony Goodin (Australia,) who have all accumulated overseas experience.
Two of the rising stars of the game in the country have again earned their place in the Bay of Plenty Fergus Hickey team line-up. Joe Carter and Sean Davey from Cadets both played for New Zealand in the 2012 ICC Under-19 World Cup. Carter burst on to the Fergus Hickey scene last season with 322 runs and a sparkling century against Poverty Bay.
Further experience is provided by Tim Clarke, Dale Swan and Bharat Popli so the scene is set for a hopefully vintage Bay of Plenty representative season which could bring multiple pieces of silverware to the trophy cabinet.
Bay of Plenty Fergus Hickey Team to play at ND One-Day tournament at Taupo 11/13 November (BOP Caps in brackets)
Jono Boult (47) (captain) Joe Carter (11) Peter Drysdale (24) Bharat Popli (26) Scott Steward (2) Ben Christensen (26) Dale Swan (20) Tim Clarke (15) Brett Hampton (19) Tony Goodin (22) Sean Davey (5) Tommy Clout (0).
ND One-Day Tournament Schedule
11 November - Bay of Plenty v Northland
12 November - Bay of Plenty v Hamilton
13 November - Bay of Plenty v Counties Manukau
ND 2012 Hawke Cup Points
Bay of Plenty 20, Hamilton 15 (defending Hawke Cup champions), Northland 10, Counties Manukau 6, Waikato Valley 4, Poverty Bay 2.
Cricket: Future stars
The two Bay of Plenty teams playing in the annual ND Primary tournament can't wait for the first round to kick off this Sunday.
In a short, sharp season programme, the Bay of Plenty Lakeland and Coastland primary representatives will back up seven days later in round two before descending on the Waikato University ground in Hamilton for a three-day tournament.
The ND Primary tournaments are the first step in the Bay of Plenty Cricket pathway, which has seen Trent Boult, Kane Williamson, Graeme Aldridge and Daniel Flynn play for the Black Caps in recent seasons.
One player to make his mark at the tournament is Kane Williamson. In 2003 the talented youngster finished the tournament with 420 runs from four turns at the batting crease and was dismissed just once.
Russell Williams, who plays for the Mount Maunganui premier team in the Baywide competitions, will coach the BOP Coastland primary side, with Rotorua age-group rep team coach Karl McKnight in charge of the BOP Lakeland primary side.
This Sunday the BOP Lakeland side travel to Gisborne to meet Poverty Bay, with the BOP Coastland team at home in Tauranga against Counties Manukau.
ND Primary Cricket Tournament schedule
11 November - Round One
18 November Round Two
21/23 November Rounds 3-5, Waikato University Ground, Hamilton
BOPCA Primary School Representatives
BOP Lakeland: Liam Hori-Clarke. Dylan MacDonald, Scott McKnight, Dilan Nanayakkara (captain) Ryan Neves, Juan Nieuwoudt, Gordon O'Donoghue, Hayze Perham, Adam Schweizer, Josh Simpson, Kahu Tataurangi, Hamish Watt. Coach: Karl McKnight.
BOP Coastland: Craig Baldry (captain) Sam Averill, Oakley Dench, Sean Dykes, Josh Earle, Reuben Fitzgerald, Kyle Hamilton, Mikaere Leef, Daniel Price, David Rout, Jarod Schneebeli, Iman Singh. Coach: Russell Williams. Manager: Steve Baldry.


text:
If you need immediate assistance, call 877-SSRNHelp (877 777 6435) in the United States, or +1 585 442 8170 outside of the United States, 8:30AM to 6:00PM U.S. Eastern, Monday - Friday.
privacy, right to privacy, right of privacy, Louis D. Brandeis, Samuel Warren, Harvard Law Review, legal history
Legal Education, Legal Writing, Legal Ethics, Professional Responsibility
bar exam, preparation, for-credit, legal education, analysis, writing, bar passage rates
bar exam, bar exam reform, MacCrate, performance test, MPT, legal education, Best Practices, Carnegie Report
bar exam, bar, exam, Pennsylvania Bar Exam, employment discrimination, bar exam subjects
bar exam, bar exam reform, performance test, legal education, UBE, Uniform Bar Exam, NCBE, National Conference of Bar Examiners, MBE, Multistate Bar Examination, bar admissions, licensing tests, licensing examinations, MPT, Multistate Performance Test, MEE, and Multistate Essay Examination
© 2016 Social Science Electronic Publishing, Inc. All Rights Reserved.
Terms of Use
Privacy Policy
Contact Us
This page was processed by apollobot1 in 0.110 seconds


text:
Oxford: Son of Queen Elizabeth I
Oxford Institute Press
By Paul Streitz
Posted November 2, 2001
Tags Alumni Books Faculty Books
The book advances the growing notion that Edward de Vere, 17th Earl of Oxford was Shakespeare by showing those biographical parallels between Oxford and the body of work known as the Shakespeare canon. It further states that Shakespeare/Oxford's body of work was much larger than previously supposed, including Ovid Metamorphoses credited to Arthur Golding and Romeus and Juliet, credited to an illusive Arthur Brooke. The book also includes a new poem When Silly Bees Could Speake, which it asserts is a poem by William Shakespeare.
The book is a direct challenge to two traditions of English history: The Virgin Queen and the Bard of Stratford-upon-Avon.
-Oxford Institute Press


text:
New subscription
Renew my subscription
Give a gift
Pay my bill
Change my address
Little One
Active within 2954 Days
Hi! My name is Little One
I am Domestic Longhair from St. Louis, MO
Nicknames: Sweet One, Hairy Sister
Age: 10 years old
Gender: F
Coat: long haired
Education: She's best friends with our other pet, Jellybean (a rabbit) They love to play together and eat each other's food.
My favorite tricks and treats are: Thanksgiving Turkey
Where I hang out: Anywhere there is people.
My favorite grubs: Purina Cat Chow, Indoor Formula
My pet peeves: baths, being alone
What I love about my owners: I love my owners because they always pet me, and love me and never want me to be alone.
My cat hobbies: listen to Christmas music, tip her water dish over, stare at people. She's very photogenic and loves to be photographed.
Pet motto: Home is where the people are.
See all awards »
We saw a poster of a kitten without a home in the orthodontist's office.
I've had 355 friends visit me.
I'm the 13,619th member on CatChannel.com.
16 friends have voted for me since I joined Club Cat!
Come visit me, Team RAGDOLL PAWesome PURRsonality #235194, :¦:Chloe:•:(¯`v´¯):•- :208036:¦: & Team CHLOE, a PAWSitively PURRfect NAME #234964.
Come visit me, Dolci's Photo Shop!! & Dolci *Loves Cupid!* BFF Mamma K+Nalah*.
Tell a Friend |
Report inappropriate content on this page.
Hi, my name is
K Sparky 08/11 ♥ Misty RIP MY BFF Rhuby.
Visit the photo gallery to cast your vote »
Get quick tips for happy cats, food recall info, news alerts and best behavior advice.
Sign up to get updates delivered straight to your inbox.
CatChannel takes your privacy seriously. To learn more, please read our privacy policy.


text:
|Women, Men, Girls, Boys, Infant/Baby
Hi! My name is Pam and I am the owner and designer of Sincerely Pam. I would say that I am best known for my use of texture and sense of humor in my designs. I am a self-taught Crocheter since Feb ...
Hi! My name is Pam and I am the owner and designer of Sincerely Pam. I would say that I am best known for my use of texture and sense of humor in my designs. I am a self-taught Crocheter since Feb 2012 having entered the design world in April 2013. What began as a simple hobby has blossomed into passion for all things fiber. In my first year Designing I published 40 patterns ranging from gotta-have Collections to animal-inspired cowls and pillows.
In Dec 2013 I become a proud member of the Design Wars community competing in Design Wars 6 and the first ever Design Wars (mini) Challenge. I was also the winner of Most Favorite Design for my Marek Vest in the Back to School Challenge 2014.
To learn more about me you can visit my facebook page www.facebook.com/sincerelypam or pop over to my blog http://www.sincerelypam.com/
Dylan Mittens - You will be smitten with these mittens!
The final pattern in the Dylan Series, these mittens were designed with everyone in mind! These are the perfect mittens for men, women and children. They pair perfectly with the Dylan Slouch or Ear Warmers to complete any fall or winter outfit. A little more modern than your average mitten pattern, these are the perfect Christmas gift, and would be a smart addition to any shop!
This pattern has instructions to make mittens in sizes infant/toddler, child, small, medium and large adult. You will need 3 colors worsted weight yarn and a G and I hook.
You are free to sell what you make from this pattern, but you may not share, copy or reproduce this pattern in part or whole.
Photographs are also copyright protected and may not be used. Please link back to one of my shops if selling your finished items online.
(c) Pamela Dajczak 2013
G hook is 4hdc=1"
I hook is 3hdc=1"


text:
!NFINITY Rihanna Diamond Heart Ring
infinity.owner posted a photo:
100% original mesh
Texture-hud for metals and diamond
Reziser scripted
Unrigged, easy to fit all types of hands
Left hand + right hand versions included. ( hands not included)
This saturday sept 24 in the SATURDAY SALE for only 75L! (mainstore only)
MP marketplace.secondlife.com/p/NFINITY-Rihanna-Diamond-Hear…
Visit https:[email protected]/29769707692/ for original news posting.


text:
KIHEI - Plans to convert the landmark Aston Maui Lu Resort in Kihei into time-share condominiums could be revived as the hotel's owners actively seek a buyer for the 27-acre property.
Owner Maxxam Enterprises of Beverly Hills, Calif., has tapped commercial real estate firm Jones Lang LaSalle of Chicago to market the resort.
The Maui Lu owners obtained a special management area permit in 2008 to demolish the 50-year-old hotel and to build a 388-unit time-share complex on the sprawling property at 575 S. Kihei Road.
The existing complex of multilevel buildings and individual bungalows sits on prime oceanfront land with 600 feet of shoreline and six miles of state-owned white-sand beach on either side, according to Maxxam's website.
The land and buildings are valued at $11.7 million for tax purposes, according to Maui County property tax records.
At least one estimate places a potential sale price at almost six times that amount. Real Estate Alert, a weekly newsletter focused on investing in the U.S. commercial market, estimates the resort's sale could attract bids of approximately $68 million.
A spokesman for Aston Hotels & Resorts, which manages the Maui Lu, referred all comments to the hotel's owners. Calls and emails to Maxxam Enterprises were not immediately returned.
The Maui Lu had been a winter retreat for Canadian logger Gordon Gibson, who named his estate after a yacht he sailed across the Pacific. It was developed as South Maui's original bed-and-breakfast as Gibson added units for friends and family who were regular visitors to his estate. Subsequent owners expanded the property, which has been in operation since 1962.
Maxxam's website says it had planned to "redevelop the Maui Lu into a 400-unit timeshare complex, complete with lush landscaping, pools and water features."
The company notes that "Maui is the world's top timeshare destination, but due to strict zoning and development regulations, the market is considerably undersupplied. As our property was already zoned properly for a conversion to timeshare, we saw an opportunity for a new strategy to leverage the full potential of the asset."
A planned sale back in 2008 to Marriott Ownership Resorts did not go through. The Maui Lu had been slated to close at that time for a three-year overhaul.
Resort employees said that the Maui Lu is still taking hotel reservations for the foreseeable future.
Maxxam also lists the Maui Park Apartments in Lahaina as another asset, along with the Waikiki Trade Center in Honolulu and the Royal Sea Cliff Condominiums in Kona on the Big Island.
* Nanea Kalani can be reached at email@example.com.


text:
State lawmakers returning to work this month are facing the same dilemma about Internet cafes they did last year: What to do with them.
A decision by the president of the Ohio Senate to not have a vote at the end of 2012 on an House-approved bill regulating the businesses has lawmakers there and in the Ohio House back at scratch, with at least one local representative hoping for a resolution by the Fourth of July.
And while lawmakers continue to tread water, some owners of the cafes are mounting an organized effort, including starting a website, to fend off regulations that would essentially eliminate the establishments.
Article Photos
Tribune Chronicle illustration
House Bill 605 won House approval 63 to 30 but didn't go anywhere in the Senate because there was little time for chamber members to address the issue.
It essentially amounted to a ban on Internet cafes by prohibiting giving away cash and capping the value of prizes at $10.
A competing bill - House Bill 195 - would have set less strict rules, but it never made out of committee.
Fact Box
Where the cafes are
Local Internet cafes by community:
Trumbull County
Hubbard - 6
Girard - 3
Warren - 24
Niles - 5
Cortland - 2
Vienna, Masury, Leavittsburg, Bristol, North Bloomfield, Mineral Ridge and Newton Falls - 1
Mahoning County
Boardman - 7
Youngstown - 16
Austintown - 7
Struthers - 2
Campbell - 2
Canfield, Poland and Liberty* - 1
SOURCE: Ohio Attorney General's Office, based on affidavits received by the office from cafes. *The attorney general lists the location as Liberty but in Mahoning County.
What's going to happen this year is anyone's guess, but one lawmaker sees a divide beginning to form.
Democrat State Sen. Joe Schiavoni, who introduced a bill in March 2012 to regulate the cafes, said a split is taking shape between those who want to eliminate the operations, also known as sweepstakes cafes, and lawmakers who want to see them regulated.
Schiavoni, of Boardman, said the cafes should be allowed to stay open, but with reasonable regulations. Players need to understand the odds of the games, the odds need to be posted inside the building and there needs to be fees in place to operate, he said.
His bill was surpassed by a decision to put into place a moratorium on new parlors and require those existing cafes to file paperwork with the Ohio Attorney General's Office.
The latest count by the state shows 821 cafes in Ohio. In Trumbull County, there are 47 and in Mahoning County, 37.
To play, customers pay for Internet time or phone cards and use them to bet points on computers loaded with games such as poker.
Operators say they sell legitimate products with a chance to win a prize.
Opponents say the Internet cafe computer games that operate like slot machines with cash prizes amount to illegal gambling.
Schiavoni said if the games are regulated as gambling, it could create a new issue, because the only way to expand gambling in Ohio is by changing the state's constitution by going to voters.
''I believe at the end of the day, something will be done, but what that something is, I can't be sure,'' Schiavoni said.
Attempts to reach owners of several local establishments to comment were not successful.
Bryan Sanshuck, executive director of the Internet Cafe Coalition of Ohio, said ''heavy'' behind the scenes, negotiations are happening with lawmakers for ''fair regulation and not an elimination of the industry.''
''Regulation is a good thing,'' he said. ''When you eliminate something, it affects many, many thousands of people statewide.''
The group is focused on saving jobs - about 16,000 are tied to the industry - and saving the revenue municipalities receive from putting fees on the cafes, he said.
Sanshuck, an industry consultant who said he doesn't currently own any cafes, said House Bill 605 would have ''killed everyone in the industry,'' plus it would have hurt other business, like food and coffee vendors and pizza shops.
The group has a website, www.internetcafecoalition.com.
The temporary ban expires at the end of June, enough time for lawmakers to vet the issue and ''take real consideration on it,'' said state Rep. Tom Letson, a Democrat who represents part of Trumbull County.
House Bill 605 was ''too much, too late'' said Letson, yet he supported it, because he believed lawmakers in the new General Assembly would revisit the issue.
''As long as we're going to have casinos and racinos, I really don't see the problem with Internet cafes or sweepstakes parlors, so long as we regulate them, we license them, we audit them and we can use some of the profits for local government funds and addiction services,'' Letson said.
House Bill 605's competitor got stuck in committee, but committee Democrats led by ranking member, state Rep. Ron Gerberry of Austintown, agreed on amendments that would have funneled some of the gross receipts from parlors toward addiction services and local governments.
A third amendment would have capped the number of cafes, not allowing any more in Ohio, Gerberry said. Other provisions included per machine fees, licensing and prohibiting the transfer or selling of that license, Gerberry said.
The Associated Press contributed to this report.


text:
"It's embarrassing, he's embarrassing," says a Lohan insider, suggesting Michael pay attention to his own responsibilities, not those of Jon Gosselin. "He's trying to get deals for Jon. Maybe Jon can tell Michael to pay [ex-wife] Dina child support. He's now six months behind."
'Total Lie'A second Lohan source tells PEOPLE that Michael owes Dina money: "Michael is six months behind in child support. Over $12,000 is due, and it's in the hands of collections now." (While Lindsay, 23, and her brother Michael, 21, are legally adults, Ali, 15, and Dakota, 13, are minors.)
Michael Lohan, however, denies the debt. "That's a total lie. I pay Dina and the kids cash all the time," he tells PEOPLE.
The Lohan insider also maintains that Michael's intentions are self-serving: "He's trying to manage Jon Gosselin, and make money from him. It's gross. It's all about money."
As for Michael's turbulent relationship with his famous daughter, the source confirms they remain estranged, and that the Gosselin publicity isn't helping since Lindsay would prefer a more low-key father: "Lindsay's still not speaking to him." A rep for Lindsay had no comment.
And in regards to Michael offering marital advice to the Gosselins, another source, says, laughing, "Michael's giving advice about marriage, and about parenting? It's absurd."
Additional reporting by DIANE HERBST


text:
WASHINGTON - House Speaker John Boehner said today that the United States should provide more equipment and other aid to the Iraqi government in its battle against al-Qaida militants, but he ruled out a reintroduction of U.S. troops for now.
The Republican leader said President Barack Obama must get more involved in helping Iraq as it seeks to reclaim two cities, Fallujah and Ramadi, overrun by al-Qaida fighters. Boehner said the U.S. has a vital national interest in Iraq and warned that the progress made by American forces before troops were withdrawn after nine years of war is being threatened.
"I think the president himself ought to take a more active role in dealing with the issues in Iraq," Boehner, R-Ohio, told reporters at his weekly news conference. "Secondly, we need to get equipment to the Iraqis and other services that would help them battle this counterterrorism effort that they're attempting to do. There are things that we can do to help the Iraqis that do not involve putting U.S. troops on the ground."
Pressed on whether he thought U.S. troops should be sent back to Iraq, Boehner said he didn't think "that is called for at this point in time."
The Obama administration has ruled out sending American troops back in, but has been delivering missiles to help bolster Iraqi forces, and more are on the way.
At a separate news conference, Senate Majority Leader Harry Reid, D-Nev., said the U.S. would assist Iraq but ruled out sending American troops back. "They're home. The American people are glad. They're coming back from Afghanistan," Reid said.
Boehner did not specify what aid the U.S. should provide, but his office cited the sale of military equipment that Sen. Bob Menendez, D-N.J., has been blocking for months.
Congressional aides said Menendez, chairman of the Senate Foreign Relations Committee, has been holding up the sale of Apache helicopters and other equipment to Iraq because of concerns the Iraqi government could use the materiel for internal crackdowns instead of national defense.
Menendez and other senators also have been demanding that Iraq exert tighter control over its airspace to prevent Iran from sending war goods to Syrian President Bashar Assad's government.


text:
NILES - The former president of the Niles Frontliners Club turned himself in to Niles police Friday in connection to a charge of theft of $21,090 from the football boosters group.
James A. Mullen III, 45, 2165 Coates Court, Girard, is expected to appear Monday morning in Niles Municipal Court for arraignment on a felony theft charge.
"If this case moves forward as a felony, it will move to Trumbull County Court," Niles Prosecutor Terry Swauger said.
The Frontliners Club is a booster organization that raises money for the Niles Red Dragon football team.
Mullen resigned as president after the funds were discovered missing from the club bank account.
Swauger said evidence indicates that Mullen wrote six checks payable to cash and made three electronic transfers between May 31 and July 23. Full restitution has since been made, according to a police report.
"I understand a check was written for the full amount," Swauger said. "The check cleared Thursday."
"The return of the money could be a mitigating factor during sentencing," he said.
Mullen has been replaced on the boosters club by Joseph Matig, Frontliners former vice president. Scott Peden replaced Matig as the vice president.
A news release issued by the Frontliners stated the organization has implemented new safeguards.
Niles police were contacted by Frontliners Club attorney Pat Parry on Aug. 31, who reported the theft.
Efforts to reach Mullen for comment were not successful.


text:
An Odd Job
WEST LAFAYETTE, Ind. – It was odd the first time Purdue's defense took the field Saturday.
The Boilermakers hadn't had much success through five games as a traditional 4-3 defense, so, with a bye week to work with prior to this game, they made a switch. Purdue came out in a 3-4 with a nose tackle lined up over center.
Saying that Nebraska was surprised is putting it mildly.
"The front they played, we didn't even practice," offensive coordinator Tim Beck said. "I don't even know why we practiced. They did everything completely different. I thought our guys adjusted well, though."
The 44-7 score seems to indicate that the Huskers as a whole handled it just fine. Tommy Armstrong's stat line indicates that he did not. The redshirt freshman quarterback, in his first road start, finally looked like a freshman.
Gone were the calm throws and smart option runs from Armstrong on Saturday. In their place were wild tosses, three interceptions, 6-of-18 passing and just 48 total yards of offense.
"After each drive, I talked to (Beck) on the headset and he said it was confusing up there for him, so he knows how it is for us on the field," Armstrong said
Purdue's gambit worked in that regard. It made Armstrong look vulnerable rather than in-control, his best trait in his first two starts. Going on the road, even to lethargic West Lafayette, always has the potential to rattle a young quarterback. The switch to a three-man front – which Beck said Nebraska hadn't prepared for "at all" — added significantly to the degree of difficulty for Armstrong on Saturday.
It's like, well, it's like that bad dream we all have at one time or another.
"It's like taking you and giving you a chemistry test right now," Beck said. "You've not studied for it, you didn't even know you had it, but I'm going to take you in there and you've got to take it in front of 70,000 people. That's what it was like for our guys today."
Minus the 70,000 people part, of course. The official numbers say there were 47,203 people in attendance on Saturday. Entire sections populated with just a few fans, many of them wearing red, say that's a lie, but the Purdue fans who stayed away were, perhaps, the smartest people not in the building.
That's because even with Nebraska playing through a pop quiz, this thing was ugly. The Husker offense sputtered a bit, yes, but the defense didn't need a surprise switch to rattle Purdue's true freshman quarterback Danny Etling. In his first career start, Etling was sacked five times, intercepted once, the victim of a Randy Gregory safety, and just 14-of-35 passing. That's what happens when your running game can generate only 32 yards on 25 carries, there's nowhere else for a young quarterback to turn. Stand in there, take your shots, and do your best, son.
Armstrong didn't have it nearly that bad. He had Ron Kellogg III to come in and calm things down with some jokes in the huddle while going 10-for-13 on the day. He had Ameer Abdullah (126 yards), Imani Cross (two touchdowns), and Randy Gregory (two sacks, fumble recovery) to help keep things cushy. He had an understanding and equally off-balance offensive coordinator.
And, most importantly, he had the right takeaway from this game.
"We won. It was a team win, but I've gotta look at it like if it was a better team, a team that was going to play four quarters, and it was neck-to-neck, it could've cost us the game."
It could've. But it didn't. Getting "teachable moments" like that as a young player are always valuable, but they rarely come in a 44-7 win.
That's the good news from Armstrong's bad day. Well, that and the fact that he was already aware of it 20 or so minutes after the worst game of his young career.
Better games will come.


text: Jesse E. Smith, a member of Boy Scout Troop 39 from the Maltby/Clearview area, is an Eagle Scout candidate with the Mt. Baker council in Everett. For his Eagle Project, Smith organized a food and gift drive that ran from Dec. 11-18 benefitting the Maltby Food Bank. He also worked with Fran Walster, director of the food bank, in compiling a wish list of Christmas gifts for four large families.


text:
- Text Size:
- ASmall Text
- AMedium Text
- ALarge Text
Enid police say suspects are being sought in the apparent shooting death of a man who was found inside a home.
Capt. Jack Morris said Tuesday that the body of 43-year-old David Richard Wimmer was found Tuesday by officers responding to a report of a man found lying in a pool of blood. Morris says it appears Wimmer had a gunshot wound to the chest and the body is being sent to the state medical examiner's office in Oklahoma City for an autopsy.
Morris says only that the body was found in the bedroom of the home and that no other details are being released.


text:
The nun and the quarterback
Somewhere in the schoolteacher's manual, there must be a warning to instructors: Never share personal information with your students.
It happened a time or two when I was in school, and the results were never pretty.
Once, in the ninth grade at Cathedral Prep, Sister Mary Gertrude, RSM, substituted for our regular math teacher, who'd called in sick. She was a veteran teacher and wise to all of the tricks played by teenage boys who, on certain days, weren't particularly interested in learning.
But even the most experienced teachers could fall victim to a skilled con artist. Before Sister began that day's algebra lesson, one of the guys somehow got her talking about students in her classes over the years.
Sister Gertrude let her guard down for only a second, but it was enough.
"You've probably taught a lot of students who went on to fame and fortune," he said in his oiliest Eddie Haskell voice.
Sister said, "It's funny you mention that because we were just talking about Johnny Unitas, who was one of the nicest boys in. ..."
As the words left her lips, she blinked twice. She knew she'd been had.
"Oh, you had Johnny Unitas in your class, did you?" he said with a smirk. "Is that the same Johnny Unitas who quarterbacks the Baltimore Colts? Or is it another Johnny Unitas?"
"That's enough chitchat," the nun said with authority. "Now, open your books."
When the class ended and we filed out, the wise guy said in a voice loud enough for everyone to hear, "Yeah, Johnny Unitas. I'll just bet she taught Johnny Unitas."
"You know," I said, "Unitas grew up in Pittsburgh, and it might have happened."
A couple of months later, I was summoned to the attendance office, where a priest motioned me into a small office. There sat a smiling Sister Gertrude across from ... Johnny Unitas. I was stunned. She made quick introductions, and I asked Unitas if he'd be addressing the student body.
"No, Mr. Unitas can only stay for a minute," Sister said. "I just thought you might like to meet him."
She instructed me to wait in another office until Unitas departed, and then she returned and swore me to secrecy. "I'm counting on you to tell no one about this meeting," she said seriously.
I nodded affirmatively, and kept my word all these years. Until now.
KEVIN CUNEO can be reached at 870-1701. Send e-mail to email@example.com.


text:
HARRISBURG - Dominic Pileggi doesn't seek the limelight. The Delaware County Republican chooses his words carefully and leads the state Senate's majority caucus with a steady hand and an unflappable demeanor.
His name is most likely to turn up on a bill revising the library code or tweaking an obscure clause in Senate rules. Flamethrower he is not.
Which made it all the more surprising to some that he has thrust himself into the center of a national debate over how America picks its presidents.
Pileggi, 53, set off a war of words earlier this month when he announced a proposal to change the way Pennsylvania awards its electoral votes.


text:
Remington All in 1 Grooming System
We're sorry, this product is no longer available.
Remington All in 1 Grooming System offers ultimate precision, complete control, and unmatched versatility with all your grooming needs.
Sherry B.
Jun 12, 2012
I bought this as a gift for my husband as his old one was about worn out. He has not used it yet, so I really can't give a true review at this time. His old one was also a Remington and has been used for years so I am expecting this one to last as well. Shipping was fast with no problems. I have been very pleased with all my Folica orders.
6 out of 6 shoppers thought this review wasn't helpful.


text:
NCAA D-II Elite Eight Team Spotlight: Limestone, S.C.
Team Spotlight
This is a daily series on the teams that will play in the NCAA Division II Elite Eight women's basketball tournament Tuesday, Wednesday and March 28 at Erie Insurance Arena.
- Nickname: Saints
- City: Gaffney (S.C.)
- Coach: Corey Fox (11 seasons, 172-137)
- Conference: Conference Carolinas
- Record: 27-5
- Regional: Southeast (No. 7 seed)
- Regional wins: No. 2 Clayton State (75-65), No. 6 Belmont Abbey (78-62) and No. 8 Armstrong Atlantic (74-55)
- Top players: Celestra Warren, a 5-foot 9-inch junior guard, leads a balanced scoring attack with an average of 15.3 points and 7.5 rebounds per game. She shoots 37.6 percent (44-of-117) from 3-point range. Ayshia McNeil, 5-foot 9-inch junior guard, averages 13.9 points per game and is shooting 35 percent (56-of-160) from 3-point range. Two other players, Jasmine Kearse (10.8) and Alicia Brookins (10.4), average in double figures. Kearse is a 5-6 guard and Brookins is a 5-9 forward.
- Tournament history: This is Limestone's third trip to the NCAA tournament, and all three have come in the past three seasons. This is the Saints' first trip to the Elite Eight. They reached the Sweet 16 in 2013 after losing in the first round of the NCAAs in 2012. The Saints are 79-16 overall in the past three seasons.
- 2013-14 losses: Armstrong Atlantic (82-77), UNC Pembroke (74-61), Georgia College (50-45), Belmont Abbey (59-53) and Belmont Abbey (74-64).
- Quarterfinal opponent: West Texas A&M, Tuesday, noon
-- from staff reports


text:
Student Employment Opportunities
- Mathematics Learning Center: The Mathematics Learning Center is frequently looking for qualified tutors. Tutors must have completed MATH 161 with a grade of B or better and have the endorsement of a mathematics or statistics professor. Also patience and a positive attitude are a must! If you are interested in tutoring for the Mathematics Learning Center, please contact Charles Whiffen.
- Private Tutoring: The Mathematics Learning Center maintains a list of Private Tutors. If you are interested in adding your name to the list, please contact Charles Whiffen. If you are interested in hiring a tutor, please contact the tutors directly from the list.
Charles Whiffen
Director, Learning Assistance Center
Office: Prince 209
Phone: 843-349-2935
e-mail: firstname.lastname@example.com


text:
The Leading eBooks Store Online
3,667,858 members ⚫ 1,180,414 ebooks
New to eBooks.com?Learn more
- Bestsellers - This Week
- Foreign Language Study
- Pets
- Bestsellers - Last 6 months
- Games
- Philosophy
- Archaeology
- Gardening
- Photography
- Architecture
- Graphic Books
- Poetry
- Art
- Health & Fitness
- Political Science
- Biography & Autobiography
- History
- Psychology & Psychiatry
- Body Mind & Spirit
- House & Home
- Reference
- Business & Economics
- Humor
- Religion
- Children's & Young Adult Fiction
- Juvenile Nonfiction
- Romance
- Computers
- Language Arts & Disciplines
- Science
- Crafts & Hobbies
- Law
- Science Fiction
- Current Events
- Literary Collections
- Self-Help
- Drama
- Literary Criticism
- Sex
- Education
- Literary Fiction
- Social Science
- The Environment
- Mathematics
- Sports & Recreation
- Family & Relationships
- Media
- Study Aids
- Fantasy
- Medical
- Technology
- Fiction
- Music
- Transportation
- Folklore & Mythology
- Nature
- Travel
- Food and Wine
- Performing Arts
- True Crime
- Foreign Language Books
Most popular at the top
Wartime on the RailwaysThe History Press 2012; US$ 18.94
From the American Civil War onwards, railways have been an important aspect of war. So important were the railways that in the First World War, the state took control of the railways, and then repeated this exercise in the Second World War. Wartime on the Railways describes the part played by Britain's railways during the Second World War, dealing... more...
Men of SteamWharncliffe 2011; US$ 10.22
Few modes of travel have the enduring appeal of steam railways. Today preserved lines, locomotives and rolling stock attract not just expert enthusiasts but more casual visitors who are keen to savor the distinctive atmosphere of a lost era in transport history. Yet these relics are but one aspect of the long story of steam, for they cannot reveal... more...
Sink The French!Pen and Sword 2007; US$ 5.99
The victorious German Blitzkrieg assault on Holland, Belgium and Northern France placed Anglo-French relations under huge strain. The Vichy surrender raised real British fears that the Germans would force the French Fleet, the fourth largest in the world, to turn against their former ally, while in fact their orders were to scuttle in the event of... more...
Escort Carrier of the Second World WarPen and Sword 2005; US$ 9.99
To the US Navy they were CVEs! To the Royal Navy auxiliary carriers! To crews of endangered merchantmen in the Atlantic and Arctic oceans they were heaven-sent protection! To their crews they were Combustible, Vulnerable, Expendable!The need for air cover against enemy aircraft and submarines brought unprecedented demand for carriers. Over 100 vessels... more...
MaltaPen and Sword 2003; US$ 10.99
The strategic importance of Malta sitting astride both the Axis and Allied supply routes in the Mediterranean was obvious to both sides during WW2. As a result the Island became the focal point in a prolonged and dreadful struggle that cost the lives of thousands of servicemen and civilians. After setting the scene for the action, this book tells the... more...
The World Sea Power GuidePen and Sword 2012; US$ 12.99
Compiled by the author of Janes Air Forces of the World, this book is a must for naval experts and enthusiasts. In one volume the reader will find the composition and details of all naval elements of a staggering 137 nations armed forces including paramilitary organizations as the US Coast Guard Service. The book starts with an introduction... more...
Royal Air Force Handbook 1939-1945The History Press 2007; US$ 36.46

Formed in 1918 from the merger of the Royal Naval Air Service with the Royal Flying Corps, the Royal Air Force was the first fully autonomous military air arm in the world. This book talks about RAF and the vital part it played in World War II. It looks at its structure, from the Air Ministry and the Chief of Air Staff down to squadron... more...
Royal Navy Handbook 1939-1945The History Press 2005; US$ 36.46

The service had to learn fast. It soon became clear that the Germans would not provide an opportunity for a major battleship-to-battleship fleet action along the lines of Jutland, but that submarine warfare and surface raiders were to be just as effective at undermining the British war effort. The Royal Navy was expected to be active... more...
Operation NeptuneThe History Press 2014; US$ 29.17

Long-awaited, the Normandy landings were the largest amphibious operation in history. Success was achieved by the advent of specialised landing craft, first seen in the landings in North Africa, heavy naval firepower and the creatiojn of two artificial harbours, each the size of the port of Dover, and an underwater pipeline. Operation... more...
5 Minute History: First World War at SeaThe History Press 2014; US$ 5.99
If the 100-year anniversary of the Great War has left you feeling a little under-informed, the 5 Minute History series is the perfect way to read up on this major conflict in short bursts and without pages of intricate detail. A perfect overview for the uninitiated, this book will inform and educate you even if you have never read a history book in... more...


text:
European Journal of Pharmaceutics and Biopharmaceutics (v.66, #2)
APV Diary (S3-S5).
Calendar of events (S6).
Editorial board (IFC).
EAPB: New Executive Committee (S1-S2).
Nanoparticles – An efficient carrier for drug delivery into the hair follicles by Juergen Lademann; Heike Richter; Alexa Teichmann; Nina Otberg; Ulrike Blume-Peytavi; Javiana Luengo; Barbara Weiß; Ulrich F. Schaefer; Claus-Michael Lehr; Roger Wepf; Wolfram Sterry (159-164).
The penetration and storage behavior of dye-containing nanoparticles (diameter 320 nm) into the hair follicles was investigated. The results were compared to the findings obtained with the same amount of dye in the non-particle form.In the first part of the experiments, the penetration of the dye into the hair follicles was investigated in vitro on porcine skin, which is an appropriate model for human tissue. It was found that the nanoparticles penetrate much deeper into the hair follicles than the dye in the non-particle form, if a massage had been applied. Without massage, similar results were obtained for both formulations.Subsequently, the storage behavior of both formulations in the hair follicles was analyzed in vivo on human skin by differential stripping. Using the same application protocol, the nanoparticles were stored in the hair follicles up to 10 days, while the non-particle form could be detected only up to 4 days.Taking into consideration the surface structure of the hair follicles, it was assumed that the movement of the hairs may act as a pumping mechanism pushing the nanoparticles deep into the hair follicles.
Keywords: Particles; Hair follicles; Percutaneous penetration; Reservoir function; Drug delivery;
Nanosized insulin-complexes based on biodegradable amine-modified graft polyesters poly[vinyl-3-(diethylamino)-propylcarbamate-co-(vinyl acetate)-co-(vinyl alcohol)]-graft-poly(l-lactic acid): Protection against enzymatic degradation, interaction with Caco-2 cell monolayers, peptide transport and cytotoxicity by Michael Simon; Isabel Behrens; Lea Anne Dailey; Matthias Wittmar; Thomas Kissel (165-172).
Non-parenteral insulin delivery by the oral route is limited by epithelial barriers and enzymatic degradation. Nanosized insulin-complexes based on amine modified comb-like polyesters were designed to overcome these barriers. Protection of insulin in nanocomplexes (NC) from enzymatic degradation was investigated. The interaction with enterocyte-like Caco-2 cells in terms of cytotoxicity, transport through and uptake in the cell layers was evaluated by measuring transepithelial electrical resistance (TEER), release of lactate dehydrogenase (LDH) and insulin transport.The protection capacity of NC and their interaction with Caco-2 cells varied strongly as a function of lactide-grafting (hydrophobicity). With increasing lactide-grafting (P(26) ⩽ P(26)-1LL ⩽ P(26)-2LL) NC protected up to 95% of the insulin against degradation by trypsin. Transport and uptake into cell monolayers increased with higher l-lactid grafting. About 25% of a 1.25 mg/ml TRITC-insulin NC dispersion with P(26)-2LL was recovered in Caco-2 cells after 90 min. A concentration dependent cytotoxicity profile was observed showing elevated LDH release and decreased TEER values. The cytotoxicity correlates with the surfactant like character of the polymers, decreasing the surface tension to 46 mN/m for the amphiphilic P(26)-2LL. The observed TEER decrease was reversible after 20 h, suggesting that the biodegradable comb-polyesters offer a promising approach to overcome mucosal barriers.
Keywords: Insulin; Nanocomplexes; Protein delivery; Enzymatic degradation; Caco-2 cells; Cytotoxicity;
Correlation between digestion of the lipid phase of smedds and release of the anti-HIV drug UC 781 and the anti-mycotic drug enilconazole from smedds by C. Goddeeris; J. Coacci; G. Van den Mooter (173-181).
The present studies were conducted primarily to compare the drug release process of the anti-HIV drug UC781 from three different smedds to the smedds digestion profile. The influence of every formulation component on the digestion process, measured as the release of fatty acids, was determined. In addition, the release of the antimycotic drug enilconazole from a smedds was investigated as well in order to study the influence of the type of incorporated drug on oil digestion. Simulsol 1292, Tween 80, Cremophor RH40, ethanol and both drugs reduced the fatty acid release. C8, C10 and C12 fatty acids, originating from oil hydrolysis, were able to reverse the inhibitory effect of phospholipids present in the release medium. Similarly Cremophor RH40 lost its inhibitory capacities in combination with Captex 200P hydrolysis. In addition, UC781 did not decrease fatty acid release in combination with a Captex 200P–Tween 80–ethanol mixture.The release of UC781 from smedds significantly increased compared to the dissolution of the pure drug. The drug release profiles were characterized by rapid and complete release followed by precipitation. In order to detect possible correlations between drug release and oil digestion, release results were compared to those of vehicle digestion experiments. Contrary to what one would assume, a higher extent of fatty acid liberation did not enhance drug release. In other words, drug release does not seem to be driven by the extent of lipid digestion.
Keywords: Smedds; Drug release; Oil digestion; Fatty acid liberation;
Synthesis, characterization and in vitro cytotoxicity studies of a macromolecular conjugate of paclitaxel bearing oxytocin as targeting moiety by Gennara Cavallaro; Laura Maniscalco; Monica Campisi; Domenico Schillaci; Gaetano Giammona (182-192).
The present study describes the experimental synthetic procedure and the characterization of a new polyaspartamide macromolecular prodrug of paclitaxel, bearing oxytocin residues as targeting moieties. In vitro stability studies of bioconjugate, performed in media mimicking biological fluids (buffer solutions at pH 7.4 and 5.5) and in human plasma, evidenced the high stability of the targeting portion (oxytocin)-polymer linkage and the ability of this conjugate to release linked paclitaxel in a prolonged way in plasma. Moreover, preliminary in vitro antiproliferative studies, carried out on MCF-7 cells, that are oxytocin receptor positive cells, showed that the polymeric conjugate has the same cell growing inhibition ability of free drug.
Keywords: Polyaspartamide; Oxytocin; Drug targeting; Paclitaxel; Bioconjugate;
Development of spherical iron(II) sulfate heptahydrate-containing solid particles with sustained drug release by Piroska Szabó-Révész; Béla Farkas; Tamás Gregor; Kálmán Nagy; Edina Pallagi (193-199).
The aim of this work was to develop a simple, economic procedure for the manufacturing of coated iron(II) sulfate particles by using a crystallization technique for the development of round particles, followed by coating with a lipophilic material. Several batches of iron(II) sulfate heptahydrate were produced by a cooling crystallization, with variation of the crystallization parameters. The spherical crystals were coated with stearin. The products were characterized for particle size, roundness, bulk density and in vitro drug dissolution. Crystallization was performed from deionized water with no addition of seed crystals and by cooling by applying a linear cooling rate. The developed iron(II) sulfate crystals were round with average diameter of 729 ± 165 μm. The best form for the sustained release of iron(II) sulfate was the sample HTP-2 which contained 11% of stearin relative to the iron(II) sulfate. The spherical crystallization of iron(II) sulfate is simple and fast, and does not require a dangerous, expensive solvent. The round particles can coat directly with lipophilic material which results in slow release of iron(II) sulfate and protects the iron(II) from oxidation and inhibits the loss of crystal water. The coated crystals can be filled into capsules to yield the final dosage form.
Keywords: Spherical crystallization; Iron(II) sulfate; Stearin; Sustained release; Roundness;
Two galactomannans and scleroglucan as matrices for drug delivery: Preparation and release studies by Tommasina Coviello; Franco Alhaique; Antonello Dorigo; Pietro Matricardi; Mario Grassi (200-209).
Two galactomannans, Guar gum and Locust bean gum, have been used as matrices for tablets to study the release of model molecules. As a comparison, matrices obtained with another polysaccharide, Scleroglucan, have been tested. Despite the different conformations that the polymers assume in aqueous solution (flexible coils for Guar gum and Locust bean gum; triple helix for Scleroglucan), when prepared as tablets, they show (in distilled water and at 37 °C) very similar release profiles of guest molecules (i.e. theophylline, vitamin B12 and myoglobin) of different steric hindrance. Furthermore, the polymers were chemically crosslinked with glutaraldehyde to obtain a network suitable as a matrix for modified drug release. The delivery of the model molecules from the Guar gum and Locust bean gum gels, and from tablets prepared from the freeze-dried hydrogels of the three polymers was evaluated, and a comparison with the tablets prepared with the not-crosslinked polymers was carried out. Experimental data showed how the presence in the matrix of a well-defined network, by introducing a spacer among the macromolecular chains, always increased the rate of delivery of the tested molecules in comparison to the release profiles obtained when no crosslinker was present. Release data from the tablets were analyzed according to a mathematical model able to determine the relative importance of drug dissolution and drug diffusion on the overall release kinetics. Good agreement was found between the simulated and the experimental data.
Keywords: Galactomannans; Guar gum; Locust bean gum; Scleroglucan; Glutaraldehyde; Theophylline; Vitamin B12; Myoglobin; Modified release;
Synchronized and sustained release of multiple components in silymarin from erodible glyceryl monostearate matrix system by Cheng Lu; Yi Lu; Jian Chen; Wentong Zhang; Wei Wu (210-219).
Development of sustained delivery systems for herbal medicines was very difficult because of their complexity in composition. The concept of synchronized release from sustained release systems, which is characterized by release of multiple components in their original ratio that defines a herbal medicine, served as the basis for keeping the original pharmacological activity. In this study, erodible matrix systems based on glyceryl monostearate and polyethylene glycol 6000 or poloxamer 188 were prepared to perform strict control on synchronized release of the five active components of silymarin, i.e. taxifolin, silychrystin, silydianin, isosilybin and silybin. The matrix system was prepared by a melt fusion method. Synchronized release was achieved with high similarity factor f 2 values between each two of the five components. Erosion profiles of the matrix were in good correlation with release profiles of the five components, showing erosion-controlled release mechanisms. Through tuning some of the formulation variables, the system can be adjusted for synchronized and sustained release of silymarin for oral administration. In vitro hemolysis study indicated that the synchronized release samples showed a much better stabilizing effect on erythrocyte membrane.
Keywords: Synchronized release; Sustained release; Glyceryl monostearate; Polyethylene glycol 6000; Poloxamer 188; Silymarin; Erosion;
Preparation and characterization of a self-emulsifying pellet formulation by Ahmed Abdalla; Karsten Mäder (220-226).
The purpose of the current study is to investigate the feasibility of producing solid self-emulsifying pellets using the extrusion/spheronization technique. Pellets were made from a mixture of C18 partial glycerides, Solutol® HS15 and microcrystalline cellulose. Pellets with good physical properties (size, shape, friability) and self-emulsifying properties were produced. The pellets were, in contrast to pellets lacking Solutol, able to transfer a lipophilic dye and a spin probe into the aqueous media. The release kinetics and the microenvironment of the pellets during the release process were assessed using electron spin resonance (ESR) spectroscopy. The ESR results showed that the hydrophobic spin probe was localized mainly in the lipid environment all over the release time. Furthermore, the formulation was capable of accelerating the release of the drug diazepam and achieving a diazepam concentration above its saturation solubility.In conclusion, spherical pellets with low friability and self-emulsifying properties can be produced by the standard extrusion/spheronization technique. The pellets are capable of transfering lipophilic compounds into the aqueous phase and have a high potential to increase the bioavailability of lipophilic drugs.
Keywords: Pellets; Extrusion/spheronization; Self-emulsifying drug delivery systems; Poorly water soluble drugs; Oral delivery system; ESR;
Development and bioavailability assessment of ramipril nanoemulsion formulation by Sheikh Shafiq; Faiyaz Shakeel; Sushma Talegaonkar; Farhan J. Ahmad; Roop K. Khar; Mushir Ali (227-243).
The objective of our investigation was to design a thermodynamically stable and dilutable nanoemulsion formulation of Ramipril, with minimum surfactant concentration that could improve its solubility, stability and oral bioavailability. Formulations were taken from the o/w nanoemulsion region of phase diagrams, which were subjected to thermodynamic stability and dispersibility tests. The composition of optimized formulation was Sefsol 218 (20% w/w), Tween 80 (18% w/w), Carbitol (18% w/w) and standard buffer solution pH 5 (44% w/w) as oil, surfactant, cosurfactant and aqueous phase, respectively, containing 5 mg of ramipril showing drug release (95%), droplet size (80.9 nm), polydispersity (0.271), viscosity (10.68 cP), and infinite dilution capability. In vitro drug release of the nanoemulsion formulations was highly significant (p < 0.01) as compared to marketed capsule formulation and drug suspension. The relative bioavailability of ramipril nanoemulsion to that of conventional capsule form was found to be 229.62% whereas to that of drug suspension was 539.49%. The present study revealed that ramipril nanoemulsion could be used as a liquid formulation for pediatric and geriatric patients and can be formulated as self-nanoemulsifying drug delivery system (SNEDDS) as a unit dosage form.
Keywords: Nanoemulsion; Ramipril; Bioavailability; SNEDDS; Phase diagrams; Solubility; Sefsol 218;
Tetronic micellization, gelation and drug solubilization: Influence of pH and ionic strength by Carmen Alvarez-Lorenzo; Jaime Gonzalez-Lopez; Marta Fernandez-Tarrio; Isabel Sandez-Macho; Angel Concheiro (244-252).
The aim of this work was to gain an insight into the self-associative processes and drug solubilization ability of a Tetronic variety, T904 (4 × 15 EO units; 4 × 17 PO units; HLB 15), in aqueous media covering the physiological range of pH and ionic strength, applying isoperibol microcalorimetry, transmission electronic microscopy (TEM), dynamic light scattering (DLS), oscillatory rheometry, and drug diffusion experiments. T904 shows two pK a (pK a1 = 4.0 and pK a2 = 7.9) and, at pH < 5.8, the diprotonated form predominates over the non-protonated one. Deprotonization of the central diamine group is a required condition for micellization, which is an endothermic entropy-driven process owing to hydrophobic interactions between the PPO chains. As the pH of the solutions decreases, the coulombic repulsions among the positively charged amine groups make the aggregation more difficult, raising the critical micellar concentration (CMC) and decreasing the size of the micelles. The changes in the conformation and hydrophilicity of the Tetronic were reflected in its gelation temperature (around 30 °C at neutral-alkaline pH; no gelation at pH < 2) and solubilization capacity for griseofulvin (2-fold greater at neutral-alkaline pH than at pH < 2) and rate of diffusion (slower at pH 7.4). Such alterations in self-assembly are relevant when using Tetronic in the design of drug delivery systems.
Keywords: Poloxamine surfactant; Polymeric micelles; Micellization enthalpy; Gel temperature; pH-sensitive micellization; Griseofulvin solubilization;
Use of calcined Mg–Al–hydrotalcite to enhance the stability of celecoxib in the amorphous form by Valeria Ambrogi; Luana Perioli; Fabio Marmottini; Carlo Rossi (253-259).
The use of compound in amorphous forms is a promising approach to improve solubility of poorly water-soluble drugs. However, during storage, amorphous state can spontaneously transform to the lower energy crystalline form and this is a limiting factor for a large commercial use of drugs.In this paper, calcined hydrotalcite was employed to support amorphous celecoxib and several preparations at different weight drug/carrier ratio were prepared. Solubility of celecoxib from the prepared systems was evaluated and its physical stability during storage at different conditions was examined as well. The results show that HTlc-calc can be used as a support of amorphous celecoxib with consequent improvement of drug solubility and physical stability.
Keywords: Celecoxib; Amorphous form; Solubility; Physical stability;
Synthesis and properties of N-nicotinoyl-2-(5-fluorouracil-1-yl)-d,l-glycine ester as a prodrug of 5-fluorouracil for rectal administration by Young Wook Yang; Jeoung Soo Lee; Inho Kim; Yun Jin Jung; Young Mi Kim (260-267).
N-Nicotinoyl-2-(5-fluorouracil-1-yl)-d,l-glycine (NFG) methyl-(NFGM), ethyl-(NFGE) and isopropyl esters (NFGIp) were synthesized and their potential as a prodrug of 5-fluorouracil (5-FU) for rectal administration was investigated. Chemical conversion proceeded either by elimination of (5-FU) or by hydrolysis of ester group. 5-FU was released from NFGIp, NFGE and NFGM 90.5%, 71.3% and 48.5% of the dose, respectively, in 80% human plasma and 79.8%, 56.3% and 31.6%, respectively, in pH 7.4 buffer solution after 48 h of incubation at 37 °C. Release of 5-FU occurred mainly from NFG esters but very slightly from NFG, which suggested that release of 5-FU was greatly dependent on the stability of the ester group against hydrolysis. Solubility (M) in pH 7.4 buffer solution was 0.13, 0.09 and 0.04 and apparent partition coefficient in 1-octanol/pH 7.4 buffer solution was 0.76, 1.61 and 4.2, respectively, for NFGM, NFGE and NFGIp, which were in the ranges suitable for rectal absorption. Plasma concentration (μg/mL) of NFGM, NFGE and NFGIp at 50 min after rectal administration to rats was 1.9, 4.6 and 6.7, respectively, and that for 5-FU was below the limit of detection. Their potential as prodrugs of 5-FU for rectal administration is suggested.
Keywords: N-Nicotinoyl-2-(5-fluorouracil-1-yl)-d,l-glycine esters; 5-Fluorouracil prodrug; 5-Fluorouracil; Rectal administration; Rectal absorption;
Effect of poly(ethylene glycol)-block-polylactide nanoparticles on hepatic cells of mouse: Low cytotoxicity, but efflux of the nanoparticles by ATP-binding cassette transporters by Yangde Zhang; Zhiyuan Hu; Maoying Ye; Yifeng Pan; Jiji Chen; Yulin Luo; Yanqiong Zhang; Lianxiang He; Jiwei Wang (268-280).
The objective of this paper is to study the effects of poly(ethylene glycol)-block-polylactide (PLA–PEG) nanoparticles on hepatic cells of mouse. Blank PLA–PEG nanoparticles have been successfully prepared and MTT assay suggested that the nanoparticles with HepG2 cell co-culture model did not cause significant changes in membrane integrity in controlled concentration range (0.001–0.1 mg/ml). Immunohistochemical analysis demonstrated that large dose of PLA–PEG nanoparticles injection (42.04 mg/kg, i.v.) did not induce hepatic cell apoptosis. From biochemical assay experiments, although the levels of SOD decreased and those of MDA, NOS increased after treatment with large dose of PLA–PEG nanoparticles injection (42.04 mg/kg, i.v.), they were all not significant (p > 0.05). Then Kunming mice were treated with large dose of PLA–PEG nanoparticles (42.04 mg/kg, i.v.) and after 4 days total RNA was isolated to elucidate patterns of gene expression using a mouse cDNA-microarray (SuperArray). Treatment with nanoparticles resulted in over-expression of a lot of ATP-binding cassette (ABC) transporters, especially two ABC transporters (ABCA8 and ABCC5/MRP5), and down-regulation of GSTP1, in comparison with the control. ABCA8 could extrude low molecular weight polymers after PLA–PEG nanoparticles hydrolysis outside the cells. We also discovered that ABCC5 expressed multidrug resistance protein 5 (MRP5) to pump out conjugate (GS-X) of PLA–PEG nanoparticles with GSH. The results were confirmed by RT-PCR. Results of in vitro accumulation and efflux experiments indicated that about 51–52% (51.5% and 52.0%) intracellular PLA–PEG nanoparticles was expulsed after mouse primary hepatocytes reached a saturation uptake of nanoparticles during the concentration range of 750–1000 μg/ml. The results suggested that ABC transporters (especially ABCA8) pump out the polymers after hydrolysis from mouse hepatic cells and large dose of PLA–PEG nanoparticles make mouse hepatic cells gain drug resistance to PLA–PEG nanoparticles.
Keywords: PLA–PEG nanoparticles; ATP-binding cassette transporter; Transport; Efflux; Drug resistance;
Fluorescein transport properties across artificial lipid membranes, Caco-2 cell monolayers and rat jejunum by Katja Berginc; Simon Žakelj; Lea Levstik; Darko Uršič; Albin Kristl (281-285).
Membrane transport characteristics of a paracellular permeability marker fluorescein were evaluated using artificial membrane, Caco-2 cell monolayers and rat jejunum, all mounted in side-by-side diffusion cells. Modified Ringer buffers with varied pH values were applied as incubation salines on both sides of artificial membrane, cell culture monolayers or rat jejunum. Passive transport according to pH partition theory was determined using all three permeability models. In addition to that, active transport of fluorescein in the M–S (mucosal-to-serosal) direction through rat jejunum was observed. The highest M–S P app values regarding the active transport through the rat jejunum were observed in incubation saline with pH 6.5. Fluorescein transport through the rat jejunum was inhibited by DIDS (4,4′-diisothiocyanatostilbene-2,2′-disulfonic acid) and α-CHC (α-cyano-4-hydroxycinnamic acid). Thus, we assume that two pH-dependent influx transporters could be involved in the fluorescein membrane transport through the intestinal (jejunal) epithelium.One is very likely an MCT (monocarboxylic acid cotransporter) isoform, inhibited by specific MCT inhibitor α-CHC, while the involvement of the second one with overlapping substrate/inhibitor specificities (most probably a member of the organic anion-transporting polypeptide family, inhibited at least partially by DIDS) could not be excluded.
Keywords: Fluorescein; Fluorescein uptake transporter; MCT (monocarboxylic acid cotransporter); DIDS; α-CHC; Mucolytic agents; pH partition theory;
Permeability assessment for solid oral drug formulations based on Caco-2 monolayer in combination with a flow through dissolution cell by Stephan A. Motz; Ulrich F. Schaefer; Stefan Balbach; Thomas Eichinger; Claus-Michael Lehr (286-295).
The aim of our study was to develop an apparatus assessing in vitro permeation through Caco-2 monolayers of oral solid dosage forms as a possible tool to forecast in vivo performance. Therefore, flow through dissolution and permeation modules were connected by means of a stream splitter. Permeation was measured in a specially designed cell, dissolution took place in the apparatus 4, USP. In order to test the apparatus for its reproducibility and conclusiveness, different tablet strengths and varying release profiles of propranolol HCl tablets were produced and evaluated. It was shown that for both tablet species, immediate and extended release, the apparatus was able to measure permeation through Caco-2 monolayer as well as dissolution simultaneously with high precision and reproducibility. The permeated amount of the three immediate release tablets with increasing dosage strength showed linear dependency on the dosage strength. Furthermore, the effect of retarded release on permeation could be detected and conclusive data for dissolution and permeation were obtained. In summary, connecting cell culture based permeability assessment with compendial flow through dissolution equipment led to promising results and poses the base for more advanced studies for detecting influences of dosage forms on permeation process.
Keywords: Oral absorption; Caco-2 cells; Dissolution; Permeation; Propranolol HCl; Biopharmaceutical classification system (BCS);
In vitro and in vivo evaluation of the transdermal iontophoretic delivery of sumatriptan succinate by Sonal R. Patel; Hui Zhong; Ashutosh Sharma; Yogeshvar N. Kalia (296-301).
The objective was to evaluate the transdermal delivery of the 5-HT1B/1D agonist, sumatriptan from an iontophoretic patch system, in vivo. Initial in vitro experiments were conducted to optimize formulation parameters prior to iontophoretic delivery in Yorkshire swine. It was found in vitro that increasing drug load in the patch from 9.7 to 39 mg had no statistically significant effect on cumulative delivery (cf. 305.6 ± 172.4 vs. 389.4 ± 80.4 μg cm−2, respectively). However, for a given drug load (39 mg) increasing formulation pH from pH 4.7 to 6.8 significantly increased the cumulative amount of sumatriptan delivered across the skin (389.4 ± 80.4 vs. 652.4 ± 94.2 μg cm−2). A biphasic current profile comprising intensities of 1.8 mA from t = 0 to t = 180 min and 0.8 mA from t = 181 min to t = 360 min was used for the in vivo experiments. Drug levels in the blood were 13.7 ± 4.5 and 53.6 ± 10.2 ng ml−1 at the 30 and 60 min time-points, rising to 90–100 ng ml−1 during the 90–180 min time-period. The in vivo results show that the pharmacokinetics following transdermal iontophoretic delivery are comparable to those after oral, nasal or rectal administration, but do not match those upon subcutaneous injection.
Keywords: Transdermal; Iontophoresis; Migraine; Sumatriptan; 5HT1B/1D agonist; Non-invasive; In vivo;
by Peter Kleinebudde (302).


text:
"I think we have them as ready as possible," he said. "Understand: That doesn't mean they'll be perfect. They're still freshmen."
Kiffin's philosophy is simple: To prepare the rookies for everything they might face in a game, you have to throw everything at them in practice. Mission accomplished.
"To put them in all of situations we have takes a lot of time, and it's for a reason," Kiffin said. "Hopefully, they continued to make less mistakes as the preseason went along, which I think we saw. I think you saw them making a number of plays today again."
With Game 1 just seven days away, some of the rookies are feeling a little nervous. Nu'keese Richardson, scheduled to be the No. 1 punt return man, fumbled a punt for the second Saturday in a row.
"Hopefully, we got some of it out," Kiffin said of the freshman jitters. "But we know a week from today there's going to be 100,000 people in here. We can't simulate that but we've done everything we can up to this point."
Richardson heads into Game Week listed as a first-team receiver on the depth chart. He also lines up as a shotgun quarterback from time to time. Fellow freshman David Oku, who is competing for snaps at tailback, also lines up as a wideout from time to time. Asking freshmen to play multiple positions obviously shows a lot of confidence in them but Kiffin says the workload isn't as heavy as it might appear.
"We tried to give them a lot initially, and now we've tried to really be specific ... more of what they would do in the first couple of games," he said. "We won't be doing any more experiments. We'll be practicing stuff we think they'll be doing the first couple of games."
The fact Oku and Richardson can line up in multiple positions is a critical element of the Vol offense.
"As we evaluate the running backs, having guys who can do multiple things is extremely important to us," Kiffin said. "Maybe it's not as big a deal to other people because they're more generic in what they do with them ... they sit back there behind the quarterback all day.
"We ask our guys to do a lot of different stuff, as you saw today. They're lining up all over the place. It's very valuable to us for guys to be (multi-purpose) threats, like both of those guys are.
"And both of those guys will be starting returners - Richardson on punts, Oku on kickoffs - so that's very significant for them."
The nine freshmen listed either first or second team are as follows:
- Nu'keese Richardson, No. 1 wide receiver and No. 1 punt returner
- David Oku, No. 1 kickoff returner
- Bryce Brown, co-No. 1 at tailback with Montario Hardesty
- Montori Hughes, co-No. 1 at nose tackle with Dan Williams
- Mike Edwards, co-No. 1 at cornerback with Anthony Anderson
- Janzen Jackson, co-No. 1 at free safety with Dennis Rogan
- Marsalis Teague, No. 2 at wide receiver behind Quintin Hancock
- Greg King, No. 2 at strongside linebacker behind LaMarcus Thompson
- Darren Myles, co-No. 2 at strong safety with Prentiss Waggner behind Eric Berry


text:
The sign outside the west Chandler gym promises boxing, but don't go in expecting to find a dark, sweaty place full of guys with busted noses and broken dreams.
Don and Jeannette Alexander opened Boot Camp Boxing Center of America in June in a strip mall on the southeastern corner of Ray and Rural roads. The 4,000-square-foot gym has a bright, airy interior, and though there is a boxing ring, it's not likely that the next Mike Tyson is training there.
Boot Camp Boxing Center offers an old-school workout with a twist. Gym members are challenged by a training regimen for boxerswithout having to step into the ring to spar with others. They also may take part in functional training, a series that works the entire body through movements that translate to how people go about their lives rather than training individual muscles or groups.
Jayce Green, 18, said his workouts have helped him take control of his life.
"I use it to control stress," Green said. "I have really bad, severe anxiety. This helps bring my stress levels down."
Green is among the few at the gym looking to step into the boxing ring competitively. He works out with trainer Rico Hoye, a former professional boxer who fought for world titles in the light-heavyweight and cruiserweight divisions.
Former amateur boxer Don Alexander, who has worked in the health-and-fitness industry for 25 years, said people are bored with the same aerobics or weight routines at most health clubs.
"I knew there had to be something better," Alexander said. "I thought about what made me happy, what got me in good shape when I was training. It always came up as boxing. So I thought about how I could give people the same results, but also have more fun. That's how functional training came into play."
Tom Littlejohn noticed the sign for Boot Camp Boxing Center before the gym was open and came in to take a look. Littlejohn, a mechanic, said he had been active most of his life but in recent years had been struggling with back problems. He said surgery last winter took care of his back issues and working out at the gym has him feeling better than he has in years.
"When they opened up, I came by one day and saw (trainer Nick Herrera) and said, 'OK, explain what you guys do,' " Littlejohn, 63, said.
"We talked and he gave me a tour. I came back and took an introductory class. (Trainer Shawn Blei) tried to kill me, but I liked it so I signed up and I've been coming back. My purpose in being here is to stop getting old, and I feel a lot better since I've been here."
Littlejohn said he wishes he would have had opportunities for better training when he was younger.
"I played baseball all my life," Littlejohn said. "I should have been doing this when I was 15 or 16 years old."
Alexander said what makes the training at Boot Camp Boxing Center different is the attitude of the trainers. Like most workout facilities, the staff is high energy, but trainers take a genuine interest in getting to know members.
"When most people ask us how we train, what makes us different, I say we train from the shoulders up," Alexander said. "We want to uncover what's going on with you, what's making you stressed or what's going on in your life that could affect your training. We want you to be able to put everything else aside and come in here and decompress."
The space in which Boot Camp Boxing Center operates helped the Alexanders refine their concept.
They initially were looking at 10,000- to 12,000-square-foot storefronts, but when they came across this location, they knew it would work for what they wanted to do.
"We got rid of free weights, which wasn't a big deal," Don Alexander said. "Eliminating the aerobics classes wasn't hard, either. We're a specialty facility, not a health club. We just had to have space for bathrooms and showers, and space for the boxing ring."
The facility includes Move Strong, a large piece of equipment that resembles the playground fixtures that kids climb on. That apparatus allows Alexander's clients to perform body-weight exercises, such as pullups, as well as movements of functional-training workouts.
The staff at Boot Camp Boxing Center recognizes there are lots of choices in the region for fitness buffs, ranging from big corporate gyms to small facilities. Alexander said he expects Boot Camp Boxing to stand out by having top-notch trainers who make a personal connection with their clients to give them a reason to return.
"In this business, there is such a small margin of profitability where you stay can open," Alexander said. "If we don't have the goods (as trainers), we don't have anything, and we know that."


text:
Are you one of the lucky citizens of the world currently wrapped in the moist, searing hot embrace of the most cruelest of seasons? Well, then, this YouTube Roundup's for you.
Queue up the below vids, stay inside and crack open a frosty beverage. We still have a least another month of this weather left on the mirage-laden horizon.
Our Favorite YouTube Videos This Week: The Heat Wave Edition
Image courtesy of Flickr, Klearchos Kapoutsis


text:
EAST GREENWICH TWP. — The township committee has agreed to enter into a shared services agreement with the board of education for their energy services.
The township committee has been exploring the option of going through an auction process for its energy needs in order to get the best rate possible, according to Mayor Fred Grant. And adding the East Greenwich School District's energy use to the program will allow them to attain a better rate for both entities.
"By doing a shared service agreement and allowing the school district in, it opens the door to allow the school district to piggy back on our auction. It makes it more attractive to someone bidding on our power because now they have a bigger load they're purchasing," Grant said.
Currently, the township pays approximately 10 cents per kilowatt hour of power, whereas the school district pays about 10.4 cents per kilowatt hour. The cost savings for sharing the service has yet to be determined, but according to Grant, other New Jersey municipalities have combined with their local school districts in the past to positive results and there's the potential for a savings of up to $70,000.
"Anything we can do to realize the most efficient tax savings, it's a no-brainer from both sides," he said. "Their taxpayers are our taxpayers."
The board of education, which still has to approve the measure, was approached by the committee on the matter and agree that any opportunity to save money is worth exploring.
"We realize it was an opportunity we wanted to take advantage of and pursue together," said Superintendent Joseph Conroy. "Any time we can save the community the cost and save some tax dollars we're open to the initiatives."


text:
Death by Degrees
Wiggle your toes, wiggle your toes… Oh damn, wrong intro. Hmm, at least something from Kill Bill 2 stayed in my memory apparently. Anyway, in Death by Degrees, "wiggle your tits" seems like a more appropriate catchphrase, because that's what the game is all about. Gameplay? Not even by a long shot!
As you might have guessed, this game is just another run-of-the-mill action game, that really doesn't add anything to this already overcrowded genre. It's not the worst I've ever seen, but it can't be called good or even satisfactory in any way.
The one big thing (or actually the two big things, if you know what I mean) this game has going for it is the main character Nina herself. Without a doubt, Nina is sexier and better-looking than even Lara "ever increasing cup size" Croft and that's exactly what Namco was after. Since they already knew they wouldn't be able to create a decent game, they just played up Nina's good looks. It already starts with the intro. Nina is fighting in the ring against multiple enemies in a way that can be elegantly described as slightly underdressed. After she manages to knock out several enemies and is declared victorious, the movie skips an hour or so and picks up again when Nina is lying by the poolside in her bikini. Yup, and it just carries on like that…
Quite possibly the worst thing about Death by Degrees is its horrible control and camera system. In stead of just bashing the buttons on your PS2 controller, you'll be twisting your right analog stick like hell. Nina attacks in the direction you've got the stick pointed. This sounds easy but it sure as hell isn't. The camera continues to pick the worst angles possible so you'll just randomly pick a direction and hope your kicks and punches hit. How unbelievable it may sound, but this tactic actually works best, since you'll be swarmed and encircled by enemies almost every time.
Of course there are combos and special attacks in the game (quite a lot of them in fact), but because of the broken control scheme you'll hardly ever use them. Just twist the right analog stick and you'll be fine, especially in Easy (which I've played). The more hits you land on your enemies, the more skill points you earn. These can be used to buy special moves or all kinds of miscellaneous upgrades. You'll also go up in level, which lengthens your life and Focus gauges.
Once you've filled a few segments of your focus gauge, you can use Nina's signature move. Hold L2 and attack a random enemy. The game will then go into some kind X-Ray vision and you'll be able to target specific weak spots on your enemy. Nina then attacks these bodily parts in a slow motion cutscene. It's a neat idea, but you won't use it very often, because of the slow-charging Focus mode.
Aside from the cool X-Ray attack, Death by Degrees doesn't cut it when graphics are concerned. All of the game's environments are blueish or grayish, which makes them way too similar and very repetitive. Aside from Nina's outfits, the game just lacks colour, not to mention detail. Textures just look blurry and washed-out and the few different enemies don't stand out in any way. Only Nina is well animated and pretty detailed, though not as great as in any of the previous Tekken games. Even though the game only has mediocre visuals, the game features abundant and pretty impressive loading times. Every time you enter a room, you're welcomed by one of these irritating loading screens.
The audio isn't a lot better, but it's better nonetheless. Nina and the rest of the cast's voicework is acceptable and the music in the game never bothered me (which is something good). The game's sound effects on the other are quite dumb. For example, everytime Nina runs it sounds like she's treading with high heels, even when she's in fact walking barefooted. Gun sounds have also been done better in pretty much every decent action game. But hey, the same thing goes for the entire game…
The game also features some nice minigames (the sniper levels and honeycomb puzzles for example), but those can't jack up the game's general level. After you've completed Nina's fairly lengthy adventure, you'll also unlock a ton of extra's, but by then I was too fed up with this game, I didn't even bother to try them. I'm sure you won't mind.
Summing things up, I just have to say Death by Degrees fails miserably in providing entertaining gameplay. The controls and camera are simply disgusting, the game doesn't look nor sound too good and the levels are boring to say the least. The game is simply all about Nina (and her twins), nothing more.
Legend of Kay UEFA Champions League 2004-2005
Leave a Reply
You must be logged in to post a comment.


text:
Tink's #69 Doe-in-Rut Buck Lure
NOW: $6.98 (30% off!)
Was: $9.99*
Product Information:
This is the scent lure that started it all: Tink's ® #69 Doe-in-Rut ® Buck Lure. This one oz. bottle contains 100% natural doe estrous urine collected from whitetail does in heat. The easy squirt top allows you to apply this scent as you see fit.
- #69 Doe-in-Rut ® Buck Lure
- 1 oz. bottle
- Easy squirt top
- Made from 100% natural whitetail doe urine
- Use with drag rags, boot pads, Tink's Scent Bombs, or in scrapes
- Tink's
Country of Origin: United StatesWeb ID: 4345231
Customer Reviews:
Rated 4.4 out of 5�by 81 reviewers.
Rated 5 out of 5�by Torino Still #1 Been using it since I've been hunting, on a drag deer always coming nose down! September 27, 2016
Rated 5 out of 5�by TW77 Great scent I have used this product for years. Works great on a drag line. November 19, 2015
Rated 5 out of 5�by Gilley Excellent product Works great deer came right to it didn't see the deer I was after but I did harvest a nice buck November 10, 2015
Rated 5 out of 5�by hannahgirl80 Excellent We used this product during youth hunting weekend. Within one hour we had a button buck come to the area in which my son had used it. The buck got within 15 ft of where he had squirted some out. I have used other similar products in the past with some success. This product really worked for us. November 10, 2015
Rated 5 out of 5�by Ccc73 Great buck attractant during the rut Tried other brands with no success Tinks 69 seems to work the best during the Wisconsin November 3, 2015
Rated 4 out of 5�by Jack Typical Received as ordered on time. I enytered this nonsense to meet the minimum. November 1, 2015
Rated 2 out of 5�by bsfishin nothing happenend I have never had any luck with any scents. I have had a lot of luck rattling and grunting and thought this might help no difference. November 19, 2014
Rated 5 out of 5�by spike29 This is the real deal I have used this product for years, especially on my drag rag I have had bucks hit that trail and never lift their head right to my shooting lane. great product November 19, 2014
Rated 4 out of 5�by JS So far so good To be honest, I haven't used this stuff in years and never did a lot of attractant type scents anyway. However, I bout this with a mini bomb canister. I did about 20 mins of scouting and found a scrape. Hung scent and bomb above the scrape and 1 hour later I had a buck on the ground. Tink's seems to be the old standard when it comes to this stuff. November 19, 2014
Rated 4 out of 5�by TLA Works great Product works good. The only downfall of this product is that it's not sold in a spray bottle to make it go farther. November 18, 2014


text:
This chick is the real deal.
Many of you will have already heard of her, and if you haven't, then get to know! She's created quite a name for herself. This post has been sitting in my drafts for quite some time, gathering dust, but it is most definitely time to talk about the talent that is
Jessie J.
Born Jessica Cornish, the young singer-songwriter has already done more than most would do in a lifetime, having performed on a West End stage, had a writing credit on a massive summer hit song – aka Miley Cyrus' Party In The USA for those of you who didn't know – and well simply, sharing her gift with the world.
She can SING. Her voice is beautiful.
Check out the acoustic version of her song, "Do It Like A Dude".


text:
Internet Software and Services
Company Overview of Flow Search Corp.
Executive Profile
Eric Alterman
President, Chief Executive Officer, and Director, Flow Search Corp.
|Total Calculated Compensation
|This person is connected to 3 Board Members in 3 different organizations across 3 different industries.
See Board Relationships
Mr. Eric Alterman serves as the President, Chief Executive Officer and Director of Flow Search Corp. Mr. Alterman founded MILCOM Technologies, Inc. He has founded numerous companies, including JED Broadcasting and New Brand Entertainment Corporation. He founded KickApps Corporation and served as its Chief Executive Officer. He serves as Chairman of the Board at KickApps Corporation. he sertved as Member of the Advisory Board at The Creative Coalition Inc. Prior to joining ...
Corporate Headquarters
155 Water StreetPhone: 917-673-1738
Brooklyn, New York 11201
United States
Fax: --
Board Members Memberships
Founder and Chairman
President, Chief Executive Officer, and Director
Unknown/Other Education 1985
Tufts University
Unknown/Other Education
The Washington College of Law The American University
Other Affiliations
Annual CompensationThere is no Annual Compensation data available.
Stocks OptionsThere is no Stock Options data available.
Total CompensationThere is no Total Compensation data available.
The information and data displayed in this profile are created and managed by Capital IQ, a Standard & Poor's company. Bloomberg.com does not create or control the content. For inquiries, please contact Capital IQ directly by clicking here.
|There is no Competitor Compensation data available.
Sponsored Financial Commentaries
Sponsored Links
Request Profile Update
Only a company representative may request an update for the company profile. Documentation will be required.
To contact Flow Search Corp., please visit . Company data is provided by Capital IQ. Please use this form to report any data issues.
Please enter your information in the following field(s):
Your requested update has been submitted
Our data partners will research the update request and update the information on this page if necessary. Research and follow-up could take several weeks. If you have questions, you can contact them at firstname.lastname@example.com.