text:
Penn State Behrend among best extension campuses
Penn State Behrend grabbed the number two spot on TheBestColleges.org list of the 10 best branch campuses in the U.S. with "with impressive reputations all their own".
Behrend was recognized for its plastics engineering program, having a high graduation rate and for being the second-largest campus in the Penn State system, behind only the University Park campus.
Behrend was beat out only by Carnegie Mellon University's Silicon Valley campus in Mountain View, Calif.
The list, published on Jan. 3, also included The University of Pittsburgh at Bradford in eighth place.


text:
Supporting your relationship with Celtic puzzle engagement rings;
traditional and custom poesy rings and Celtic wedding rings; and exclusive bridal sets.
Shipping Worldwide - U.S. and Canada Toll-Free 866-573-7381 - Overseas 505-898-1107 - Since 1983
Instructions are the same, whether your puzzle ring has stone(s) or not. Have a cup of tea or a glass of wine, relax and enjoy the process of learning! You'll find the results gratifying and well worth your effort.
Animated and Written Six-Band Puzzle Ring Assembly Instructions
The band marked 'Greene' is held at the top and there are two pairs
of sides hanging from that. These pairs must have their tips paired
up and pointing away from each
2. The band at
the bottom is brought toward you and up, like a book being closed.
After it is brought up it is in front of the one marked 'Greene'.
The band that was brought up from the bottom is turned around. The
right side comes toward you, the left side moves away from you. The
band turns around like a top turning on its point. After turning
it around, this band is placed against the one that is marked, covering
up the 'Greene.'
3. The sides, shown
with color dots on the tips, slide through the openings created in
what will be the top design of the ring. Each pair of sides is slid
along to get their tips into the center of the ring. The flat back
part of each is outside
the ring.
4. The sides are
now folded up, starting with the upper one on the side close to you.
It is shown with the red color dot. Its tip must pass over the tips
of the other three, also marked with dots. The next band to bring
up is the upper one on the far side. Its tip (blue dot) goes over
the two remaining pieces (white and purple). The next piece to be
brought up is on the closer side. It and the last one from the far
side can come up together, but make sure the tip of the closer one
goes over the tip of the farther one. This is white tip over the
purple tip. So the order of the tips is red, blue, white, and purple.
Each tip going up and over the tips of the sides that still need
to be placed. This going back and forth side to side places the sides
in an alternating fashion.
For your protection, we
make every effort to ensure that all information on our website
is accurate, and we are proactive in seeking a fair resolution
if you are affected by an error, omission, typo, etc. on the
website. However, we cannot be held liable for such errors, omissions,
or typos, etc. If we cannot reach mutual accord, Crystal Realm's
decision will be final, and you are free to cancel your order
and receive a refund, if charged. We appreciate your understanding.

subset: commoncrawl


text:
left hand .223
Tools and Technologies
Rifle Country
> left hand .223
June 13, 2009, 07:16 AM
g'day i am wanting to buy a left handed 223 bolt action rifle. iam am asking for any suggestions please.
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June 13, 2009, 10:28 AM
I've owned two, a Charles Daly mini-Mauser and a CZ527. The use is as a walking varminter. I'd worked up a load for the Daly, which is actually a Zastava Mauser, & got it to be an MOA gun. Which is really all that I expect from a light barrel firearm.
However, after participating in the Charles Daly thread here, I found out the gun is one of 130 complete LHB mini-Mauser's imported into the U.S. under the Charles Daly name. I've written to KBI/Daly requesting a letter of provenance for the gun. Always nice to have down the road.
And, the gun has some pretty nice wood too.
Therefore, I have kinda retired the Daly & bought the CZ527. I'm still in the process of load development for it, but near completeing the process. In fact, I'll be going to the range later today to prove the load that certainly seems to work the best. Then I might fool around with some seating depths, but I really can't complain about a gun that shoots .6's.
Hope this helps, 900F
June 13, 2009, 02:10 PM
Savage makes a few models in .223 for a southpaw.
Just look for left handed models in the listings.
I've got a Mark II left hand .22LR and really like it.
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80th birthday card
Handmade 80th birthday card, can be for any age 18th, 30th, 40th, 50th, 60th, 70th, 80th, 90th, 100th
A very classy and elegant handmade card to send congratulations to celebrate a special birthday. Simple but lovely!
Featuring the number "80" die-cut from glitter card, with a personalized printed message.
The printed message can be personalized to any message you require and in a range of fonts. The fourth photo shows the fonts available. The large sparkly numbers can be supplied in a range of colours - see the last photo for the choices. Please leave details of the colour, font and message you would like in the notes as you check out. The card shown uses rose pink glitter card and Font No 1. If no details are given the card shown in the photos will be sent.
This designer card measures 14 cm x 14 cm approx (5.5ins x 5.5ins). It will be supplied with a quality envelope, in a protective cellophane sleeve. All cards are packaged carefully to ensure they arrive with you in pristine condition. As I make all my cards individually, the card you receive may differ very slightly from the photograph. However all cards are made to the highest standards and only high quality materials are used. Please note that the colors of the card may vary slightly different from those on your monitor.
This card is blank inside for your own message. A message of your choice can be printed inside for a small (£1) additional cost but please contact me prior to ordering.
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This item is made-to-order and will be posted to you by PaperDaisyCards2 within 5 days of receiving payment.
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text:
The South Carolina Stingrays signed Patrick Cullen to amateur tryout contract on Tuesday just hours after forward Daniel Koger was called up to the American Hockey League's Hershey Bears.
Cullen played four seasons at Rensselaer Polytechnic Institute where he recorded 24 goals and 38 assists in 136 games for the Red Hawks. In 33 games as a senior, Cullen had six goals and eight assists.
"Patrick attended the Washington Capitals developmental camp a couple of times," said Stingrays head coach Spencer Carbery. "He's a guy that can make plays and has a very good shot."
Charleston Battery midfielder Alex Caskey was transferred to MLS' Seattle Sounders.
Caskey played in 22 games for the Battery last summer, scoring one goal an adding an assist.
SoCon awards
College of Charleston sophomore Dena O'Brien was named the SoCon athlete of the month for women's indoor track and field.
Stephanie Saylors Saylors posted a 5-1 record with 0.86 ERA in her 40 2/3 innings of work as the SoCon softball pitcher of the month.


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CRAIC Technologies has announced Raman Spectral Surface Mapping™ (S2M™) capabilities for its Apollo™ Raman microspectrometer line.
S2M™ gives CRAIC Raman microspectrometer users the ability to map the Raman spectral variation of their samples with microscopic spatial resolution.
Surface profiles can be created from Raman microspectral data from the CRAIC Apollo™ Raman microspectrometer.
Apollo™ Raman microspectrometers can now created highly detailed spectral maps with micron scale resolution of Raman spectral features rapidly and automatically.
"CRAIC Technologies has worked to develop the Spectral Surface Mapping™ package because of customer requests. Adding Raman spectral mapping was an obvious step. Our customers wanted the ability to automatically survey and characterize the entire surface of samples by their Raman spectral characteristics. They also wanted a high spatial resolution" states Dr. Paul Martin, President of CRAIC Technologies.
Dr. Martin continued, "S2M™ with the Apollo™ Raman microspectrometer does just that. It allows you to collect spectral data from thousands of points with a user defined mapping pattern. The user is then able to analyze the entire object by changes to its Raman spectral characteristics. The user can also pull up the full spectrum for each point."
Spectral Surface Mapping™ includes a software module to be used with CRAIC Technologies MINERVA-Raman™ microspectrometer control software.
When employed with CRAIC Technologies Apollo™ Raman microspectrometers with programmable stages, S2M™ allows a user to automatically take spectral measurements with user-defined mapping patterns that reach to the limits of the stage itself.
With the ability to measure up to a million points, high definition maps of the Raman spectral response of the sample may be generated.
And because of the flexibility and power of the software, Raman spectral responses may even be collected and mapped when used with CRAIC Technologies Apollo™ Raman microspectrometers.
S2M™ gives even more power to the scientist and engineer to study the entire surface of their samples at the highest level of detail.
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• The function of the output transducer of an implantable hearing aid was assessed by applying it to the stapes head in seven fresh human cadaver temporal bones while observing vibration of the stapes under a microscope with the use of a stroboscope and a video measuring system. The transducer was a 5 × 1.2 × 0.6-mm piezoelectric ceramic bimorph with attached metal holder. Transmission changed with the amount of force holding the transducer tip on the head of the stapes. An optimal connection between the vibrator and stapes produced better transmission than a tight or loose connection. Gluing the connection with cyanoacrylate cement decreased transmission in the optimal connection, produced no change in the tight connection, and improved transmission in the loose connection. Comparison of stapes displacement produced by the vibrator at 1 kHz with that produced by normal middle-ear sound transmission revealed that the vibrator-induced stapes displacement for a 1 V peak-to-peak input was equivalent to that produced by a sound stimulus of 90-dB sound pressure level at the tympanic membrane.
(Arch Otolaryngol Head Neck Surg 1987;113:1078-1081)
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Welcome to WebmasterWorld Guest from 188.8.131.52
Forum Moderators: open
I'm not quite sure what's happened, but somehow my site has gone from looking normal and lovely and perfect to being completely messed up. The main thing I notice is that there are all these weird grey areas in the preview pane in Dreamweaver. Here's a screenshot:
And here's how it's SUPPOSED to look:
This is also how it looks on my computer, but I checked my site from a friend's computer today and it was completely messed up! There were weird semi-transparent spaces where all the grey stuff is appearing in Dreamweaver.
You can take a look for yourself at [ladylicorice.com....] I'd be interested to see if it displays properly for most people, all people, or no people.
Has anyone ever come across this before? I have no idea how this happened. :(
How much do you know about HTML; can you read the code and find any errors?
Also, I don't know if it's OK to post this here (You haven't gotten any answers yet)- but there is a google group devoted to DW - they get hundreds of questions asked and answered daily. Everybody reading the group uses DW.


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Nashua officials are pledging to investigate why public workers racked up big tabs for sausages at a local restaurant while working on a sidewalk project.
Click to watch News 9's coverage.
The Nashua Telegraph obtained records that show city workers made 38 purchases at The Sausage King of Nashua from August through November 2012. The purchases totaled nearly $1,500, and a supervisor authorized that the food could be paid for by the city.
Because the city has a line item in its budget for such things, it's not illegal. But Mayor Donnalee Lozeau said the privilege was abused.
"Thirty occasions over a four- or five-month period -- that's just excessive, and that's poor judgment, and it shouldn't have happened," Lozeau said.
Restaurant owner Dave Manganello said the purchases represent a lot of visits by a lot of people.
"It represents probably nearly 40 visits with no less than two people at a time, more like 10 to 15 at a time," Manganello said.
Lozeau said the supervisor that authorized the tab no longer works for the city for unrelated reasons. She said the meal fund is supposed to be used during extraordinary circumstances such as snowstorms or local emergencies, and a review is underway to ensure the policy is followed in the future.


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eClinical 2011: Remedies for the Clinical Trials MachineCan the emergence of new technologies improve the miserable state of clinical trials?
February 1, 2011 | An assortment of emerging clinical trial technologies over the past decade are providing creative ways for pharmaceutical companies and clinical research organizations (CROs) to boost the quality, pace, and efficiency of their drug development programs. The promise is sporadically realized by companies that selectively and appropriately apply these tools and use timely and visible performance metrics as the basis for relationship-building with clinical investigators. Working recipes are not often diligently followed, however. Thus clinical trials performance, in the main, remains dreadful.
Thanks to benchmarking by the Tufts Center for Drug Development, it is widely known that five out of six trials fail to meet their enrollment targets and half of all first-time investigators never participate in another trial. Protocols have become increasingly complex and out of touch with real-world patients and clinical habits. "If clinical trials were patients, then most would require hospitalization and many the ICU," says David Hardison, chief health scientist in the public health operations of Science Applications International Corporation. The acuity of the dysfunctions in clinical development today necessitates emergency rescue of most trials during some critical point of their execution.
Norms for how clinical trial data get collected, moved, and analyzed have fundamentally changed over the past decade. Studies once steadfastly done on paper now routinely utilize electronic data capture (EDC) and digital diaries the world over. New information-sharing and trial simulation tools have emerged for improving human productivity, keeping studies on track, and restraining costs. Accelerated acceptance of data interchange standards has also unleashed the very real possibility of using electronic health records (EHRs) to improve protocols and stop patient-recruitment log jams.
EDC is no longer just an instrument for collecting patient information on a case report form (CRF). Increasingly, it also provides near-real-time supply chain and enrollment information in lieu of freestanding interactive voice and web response systems. Some EDC systems also have some fairly robust adverse event (AE) reporting capabilities and can easily add electronic patient-reported outcomes (ePRO), says Hardison. Oracle's Phase Forward is practically a full-fledged clinical trial management system.
Market leader Oracle now has every signal-detection and safety reporting system under its wing (see, p. 29), excepting Aris Global and Sentrix, says Steven Lefebure, Gartner life sciences analyst. Although the field of EDC companies is vast, Medidata stands out as the next largest player followed by a tier of companies—Datatrak, BioClinica (see p. 15), OmniComm, Nextrials, and KIKA—seeking better positioning with broad, suite-based offerings. Differentiation between players on core EDC is difficult to see. Solutions are typically offered on a hosted or Software-as-a-Service (SaaS) basis, for sponsors disinterested in maintaining IT infrastructure.
Clinical research organizations are selectively building their EDC expertise, wielding greater control over which tools ultimately get deployed, says Lefebure They're also ratcheting down pricing by tapping into technologies via pay-per-use agreements. Small EDC providers that cannot differentiate or expand their "function footprints" may soon find themselves unable to compete. The exceptions include niche players like Akaza Research, whose free OpenClinica software is being used by organizations worldwide. Revenues from OpenClinica Enterprise Edition keep the company afloat.
The software code behind most eClinical technologies, once entirely proprietary, is slowly becoming more openly available. The National Institute of Health's caBIG (cancer Biomedical Informatics Grid) has given some steam to the movement, says Hardison. The initiative links researchers, physicians, and patients throughout the cancer community in hopes of reducing costs, speeding research discoveries, and improving patient outcomes. Open source is a guiding principle and underlies caBIG tools.
Unfortunately, caBIG has become an unnecessarily expensive undertaking, argues Velos eResearch CEO John McIlwain. The National Cancer Institute (NCI), by its own admission, has spent $200 million on caBIG over the past six years and as yet only a handful of sites are fully operational. "Over the same timeframe and for far less money, Velos has been adopted by about 35% of the nation's NCI-designated cancer centers," says McIlwain. Were Velos serving as the EDC vendor for caBIG, all constituents in the NCI cancer research community would have access to the software for free. "Much of what caBIG is trying to build is already available within Velos." The company was in fact selected and then abruptly deselected as a caBIG EDC vendor, replaced by industry-focused Medidata.
McIlwain reckons that EDC as we know it today will disappear in another five years. Investigative sites will instead use similar technology already in production at sites, together with data collected directly from EHRs, laboratory systems, and medical devices. This "direct data capture" approach, aided by improved data standards, has great and largely untapped potential for increasing the efficiency of clinical trials, he says.
Capturing the Patient Perspective
Like EDC, digital diaries offered by outfits like Invivodata and PHT are now in the mainstream, says Hardison. "Even the FDA says reliability of [ePRO] data is sufficient to support a submission. This is in contrast to issues with paper just a few years ago, when you would hear stories like, 'I saw a patient filling out a month's worth of diary data in the parking lot prior to their visit.' Now, if an indication is conducive to ePRO, it's written into every clinical trial protocol."
Quintiles' ePRO partner Invivodata, together with PHT and CRF Health, collectively control the majority of the ePRO market that is device-driven, says Lefebure. EDC vendors like Oracle are offering Web-based ePRO solutions. Software developer Merge Healthcare has ePRO options for collecting patient data via phone, device, or the Web. And Exco InTouch has a cell phone-based ePRO solution.
The interests of science should dictate which ePRO approach is the "best fit," says Ken Kolenik, director of product management at Invivodata. E-diaries have, until recently, been the only option and remain his recommendation for most trials requiring patients to self-collect data at home. In addition to proven "equivalency" with paper-based measurement, he says, single-purpose ePRO devices are patient-centric in design and functionality and suitable for any demographic. Most recently, cell phone technology has automated data transfer and eliminated reliance on patients to dock diaries on a dedicated cradle.
Web-based solutions are still largely untested, says Kolenik. Variability in screen size means patients may have to scroll through questions rather than view them all at once, potentially influencing responses. In some countries, Web access is also relatively limited. On the other hand, Web-based ePRO may be an economical alternative for some post-approval trials where patient demographics are less important, or to gather data that will not face regulatory review.
Information-Sharing Simplified
On the collaboration front, email is no longer the last option standing, says Hardison. Skype, social networking sites like Facebook and YouTube, and Microsoft's ubiquitous SharePoint portal technology provide options aplenty for keeping even the most technologically challenged colleagues connected. "We're moving into the phase where enterprises are ready to start using these tools rather than look for the next big breakthrough," says Hardison.
Major pharma companies have been making the shift to SharePoint over the past 12-18 months, primarily as a portal for internal information-sharing and communication between study monitors and investigators, says Guido Roumans, global director of life sciences services at TechTeam Global. The regulatory solutions of NextDocs are fittingly SharePoint focused, adds Lefebure. And last summer, QUMAS made a major update to its product suite to accommodate the growing popularity of SharePoint tools. BioClinica has smartly based its entire platform on the user-friendly, easily integrated application.
Companies like CSC are building document management and collaboration solutions (FirstDoc and FirstPoint) that capitalize on SharePoint's familiar user interface. Other SharePoint-based tools are giving visibility to protocol details such as actual-to-target patient enrollment, says Egbert Schröer, industry manager for Microsoft's manufacturing and resources team. "A clinical trial management solution comprises several [such] portal views, each customized with relevant information relating to specific team members and tasks." Trial progress can be tracked by study, site, and staff member from one centralized place, streamlining administrative processes while providing sites with online access to essential information and documents.
In terms of enabling critical information flows for engaging participants in the trial process, Gartner last year named IntraLinks (along with Pramata and Virtify) a "cool vendor" in the life sciences. The newly-public company, with a proven history in the financial services industry, provides a SaaS platform for securely sharing sensitive documents and tracking information flow associated with clinical trial management. More than 60,000 investigative sites are using IntraLinks to access study documents and communicate with multiple sponsors across multiple studies online with one username and password.
IntraLinks gives sponsors the wherewithal to quickly pull together information—including feasibility surveys, financial and confidentiality agreements, informed consent documents, and 1572 Statement of Investigator forms—from sites around the world, facilitating study start-up, says VP product marketing, Alison Shurell. It can also immediately alerts sites of protocol amendments and safety concerns once a study is underway. Tasks lists, due dates, and reminders can all be automatically generated with the latest release of IntraLinks, removing the risk of human error. Sponsors also gain a real-time dashboard view of study progress by and across sites, so study monitors know where to focus their attention. The platform is a connection point to IRBs and CROs as well.
Many trials still rely on email for document exchange between sites and sponsors, but that could be changing. A recent IntraLinks study found most sites willing to try an online study management tool. Large companies sometimes rely on internal IT expertise to create a Web interface for information sharing, but managing end user support tends to get "overwhelming."
Capitalizing on EHR data
Sponsors everywhere are still struggling to find qualified study participants. Companies are increasingly turning to Facebook and Twitter to aid their recruitment efforts; Pfizer even has its own YouTube channel (http://www.youtube.com/user/PfizerClinicalTeam) for enlisting people into trials, says Roumans. But compared to the industry it regulates, the FDA is a social media connoisseur. Only a handful of pharma companies have active blogs.
Innovation in the EHR space may well open the recruitment floodgates. Until now, EHRs haven't proven particularly useful for clinical research purposes because data are recorded to maximize reimbursement rather than meet the exactitudes of science. But in its unique collaboration with the Mayo Clinic, one clinical services company seems to have crossed the digital divide. Centerphase Solutions has developed a proprietary methodology for tapping more than 7 million de-identified Mayo Clinic patient records to optimize trial protocols and the study feasibility process. Early results (see "Seeking Solutions") indicate that Centerphase could vastly improve trial enrollment by translating the results of the feasibility analysis into pre-qualified subjects who can be approached for study participation.
Standards to the Rescue
Clinical research is increasingly being standardized, thanks largely to the efforts of the Clinical Data Interchange Standards Consortium (CDISC). "Significant progress has been made toward eCRFs with an agreed-upon format regardless of EDC vendor and protocol standards, which together can optimize workflow from protocol authoring to final study reports and regulatory submission," says Hardison, former CDISC board chair. Nextrials still has the only EDC product (Prism) supporting the CDISC Healthcare Link Initiative focused on EHR/EDC interoperability. Potentially huge efficiencies can be realized by integrating workflows for clinical research and clinical care in terms of information sharing, reduced data entry, and improved data accuracy (see p. 18).
"There is still a lot of custom interfacing between applications in the clinical study landscape," says Lefebure. Although CDISC's Operational Data Model (ODM) and other standards have enabled a lot of plug-and-play type of applications, they can't erase all integration issues, he notes. "There may be data points not in the ODM standard or an extension added to it or information about the data—the metadata—that needs to be shared [and] requires interpretation by data managers." Standards in general are in a "never ending race" with next-generation IT.
Data exchange standards are enabling the Cleveland Clinic, in partnership with health care informatics company Explorys, to create a set of analytic tools to do clinical trial protocol modeling and patient selection from within the institution. For the first time this year, the value of standards in improving the speed and quality of clinical research will undergo large-scale testing by a fledgling collaborative of AMCs, pharma companies, and health IT organizations known as the Partnership to Advance Clinical electronic Research (PACeR). (The collaborative is being sponsored by the Healthcare Association of New York State as part of its larger goal to create a self-sustainable health care IT infrastructure.)
The idea is for hospitals participating in PACeR to build out their EHRs to be more valuable to both clinical care and clinical research, says David Leventhal, director of health care informatics at Pfizer. Merck, Bayer, Roche, Johnson & Johnson, and Quintiles have joined Pfizer as participants, helping to underwrite the cost of the initial EHR "gap analysis" and integration of clinical trial data elements by a start-up group of hospitals in New York State. The hospitals will ultimately reap revenues from any pharma company wanting access to the enhanced and de-identified patient data to improve protocol design and patient recruitment. PACeR is expected to expand into other states in lockstep with EHR implementation. Adherence to CDISC and HL7 standards will allow co-mingling of data across institutions. Industry will gain access to between 11 and 15 million research-optimized patient records this year alone, Leventhal predicts.
First movers in PACeR get not only early access to the data but the opportunity to proactively face the steep change management curve implied by "right sizing [protocol] eligibility criteria in the presence of real-world data," Leventhal says. "The value proposition couldn't be clearer," he adds, given the volume of protocol amendments bloating trial budgets and cycle times industry-wide. Within Pfizer, he is personally endeavoring to better align the language of clinical research with ICD-9 codes and lab values the clinical care community uses to identify patients and define diagnoses.
The tactic of GlaxoSmithKline over the last few years has been to proactively identify EHR-enabled sites that can help it optimize protocol feasibility, site selection, and patient recruitment, says Philip Burstein, VP health care data optimization. "Some [investigative] sites are able to take a protocol, tell us approximately how many patients they can identify for possible recruitment, and then utilize their EHR systems to do [that recruiting] with varying degrees of success. We do think this will be heavily used in the future."
Room for Improvement
Currently, about half of the time and dollars spent on data management is consumed simply getting data from disparate sources ready to be analyzed (via well-vetted tools like SAS and Spotfire) by statisticians, medical directors, study monitors, and project managers over a trial, says Hardison. Applications based on service-oriented architecture allow for functionality across multiple systems and thus more immediate insights from tsunamis of incoming data—and at a fraction of the cost of writing "bespoke interfaces" to connect silos of point solutions. eClinical technology vendors have been "slow to keep up with best practices in other industries around system architecture, but we're starting to see evidence that they're catching up," he adds. But even the largest pharma firms still rely heavily on Excel spreadsheets to track and report on clinical trial activity.
Overall, data quality has "much improved" over the past decade but expectations have also risen, says Lefebure. Many of the quality gaps can be tied to reporting requirements in study protocols that fail to capture data precisely or with the right tools.
Trial simulation software, which could help companies plan and control trial resources and costs, remain grossly under-utilized, he adds.
Few sponsors today are doing "end-to-end" study management by thinking through a holistic set of work activities during the planning stage and then managing against that multi-disciplinary blueprint, says Lefebure. But industry overall rated the practice as having "breakthrough potential" in a 2010 Gartner survey. ClearTrial has unique and useful software for integrating and managing clinical trial operations, he notes, giving sponsors a means to intelligently parcel out limited resources. BioClinica has a clinical trial supply forecasting tool (Optimizer) that both simulates and optimizes trial activity. Even generalized analytical tools, like IBM Cognos, can help sponsors achieve a healthier balance between study planning and execution.
Companies might also want to integrate their IT and logistics support during trials, says Roumans, so sites and monitors can stop calling multiple help desks. This is displeasing to already hard-to-recruit investigators and can add to trial delays by making over-arching issues hard to detect, leading to support duplications and inefficiencies. But the tide appears to be turning. TeachTeam Global has or soon will integrate 24/7 support for three of its 12 industry clients to cover all eClinical technologies for site personnel, study monitors, and sponsor study management, effectively turning the help desk into a "clinical research operational contact center."
The performance deficiencies are so great that sponsor movement on any of the improvement opportunities would have the effect of moving the bar at least a tad north of abysmal. "Sponsors and CROs might do well to apply some of the principles learned from supply chain optimization," says Hardison. This would naturally involve helping investigators gain intimate knowledge of their patients, including what attracts them to participate and what keeps them enrolled. "Remember that a chain is only as strong as its weakest link." •
Centerphase Solutions serves as the Mayo Clinic's single external channel for industry-funded studies and assembles recruitment and communication plans on its behalf. To ensure a protocol is feasible, inclusion and exclusion criteria first get analyzed quantitatively against de-identified patient information in Mayo's expanding Enterprise Data Trust. Chart reviews and subject matter experts then qualitatively evaluate the factors impacting subject willingness to participate in the trial. The result is a more confident enrollment projection as well as pointers to which sites are likely to perform well and improvements in the site selection process.
President/CEO Gary Lubin notes that Centerphase has to date conducted more than 25 protocol reviews across study phases and therapeutic areas for ten pharma companies. In the first of four studies started at Mayo, Centerphase took 155 days to get the first patient enrolled in a phase IIb neurological study—well below the 210-day median for all studies—and could have done so in 81 days but for contractual delays. The 21-day period between site activation and first patient enrolled was notably compressed relative to the 90-day median.
Impressively, the Mayo Clinic principal investigator (PI) enrolled patients 30% faster than the other 150 sites on the study, and within the shortest relative timeline (1.2 months), says Centerphase chief clinical officer Beth Harper. Eleven of the 12 patients screened were ultimately enrolled. The enrollment period closed earlier than expected, she notes, preventing the PI from achieving his target of 15 subjects. The study effectively substantiated the predictability of the Centerphase-Mayo Clinic model, with actual versus planned pre-screen, consent loss, and screen fail ratios within 10 percentage points.
Enrollment statistics on a subsequent phase III gastroenterology study with the same sponsor are yet more compelling. Mayo was among the first wave of sites initiated—a rarity for an academic medical center (AMC) with its own institutional review board (IRB)—and shaved another three weeks from the site activation timeline relative to its initial efforts. Mayo enrolled three times as many patients as the average site and did so at a 50% faster rate.
The Centerphase vision is to build a nationwide network of AMCs and medical systems as study "centers of excellence," says Lubin. A second AMC is in the process of coming on line, with Centerphase in "serious discussions" with three other AMCs as it plans for the build out. Theoretically, data can be extracted in the aggregate across disparate EHR systems as long as Health Level Seven (HL7) and other standards for interoperability are followed and definitions of data are consistently applied. But integrating the EDT with other major data sources could prove tricky, says Hardison, who serves on Centerphase's advisory board. Mayo is one of few provider organizations that have put business processes in place to ensure EHR data can be exploited for clinical development.
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text:
Operation Spacehog
Single Player - Yes
Multiplayer - No
Fullscreen Not Available
Theme: Science Fiction
Aliens are attacking and its your duty to save the planet (yup you have heard that one before). Good graphics, catchy music, flawless gameplay and the list goes on.
Megazell's Comment - Another great game by 'Free Lunch'. Again you can say NO to the toolbar.
System Requirements
OS: Windows 2000 or higher
CPU: 750 Mhz
Memory: 32 Mb
Video: 32 Mb
Hard Drive: 1.05 Mb
Download it here - http://www.brotherso...n-spacehog.html
--> Click Here! <--
For The Full List Of 'Free And Legal PC Games.'
Edited by Megazell, 15 September 2012 - 07:59 AM.


text:
Pios on Honor Roll as league play begins
By: Tom Brown
CROWLEY – Mid-term grades have been posted and the top ranked Notre Dame Pioneers are on the way to another Phi Beta Kappa season. The Pios won for the 34th straight time in the regular season last Friday at Eunice in the final pop quiz before District 5-3A play.
There is little question that Notre Dame has hit the books hard and adjusted to the lesson plan. The results have been just as obvious.
"You have to be happy with the way we are playing and heading toward doing what we want to do on the field, but you don't want to peak right now," noted Pios coach Lewis Cook. "We want to keep getting better at what we are doing and be making that surge up and playing our best football at the latter part of the season."
So, here's our take after five weeks in the classroom. For the record, the coaches had no input on our grading.
Record A+
It's hard to argue any other mark for a 5-0 team that hasn't lost a regular season game for three and a half years. St. Louis was a close call, but the Pios found a way to win. The opener against Teurlings was eye opening, Breaux Bridge was not as explosive on offense, but they didn't score either, Christian Life was a good practice and Eunice was easier than expected.
Defense A-
The bar was set high last season and this defense has jumped up, grabbed it and done a few chin ups on it.
Eight players started the year in different positions and it hasn't seemed to matter.
The secondary has been almost unbeatable with Ricky Stoma returning three interceptions for scores and Luke Bourgeois having a hand in 32 tackles.
John Rothermel moved to middle linebacker and leads the team with 58 tackles, five for losses, a sack and five forced fumbles. Will Fruge has added 30 tackles, 3 for losses, with an interception and a fumble recovery. Kevin Johnston went from safety to end and has logged 22 tackles, eight for losses, three sacks and six QB hits. Johnston has also blocked a punt, recovered that block for a TD and recorded a tackle for a safety. Jerry Menard leads the front with 29 tackles, five of those for losses, and a sack.
As impressive as the defense has been, St. Louis was able to move the ball as well as anyone has the past few seasons against Notre Dame. The coverage lapse late in the game almost cost the Pios a win so there is still room to improve the grade.
"I didn't think we would be as far along as we are with eight guys in new positions, but they are all experienced players," continued Cook. "Even against St. Louis, they would get a nice run on us and the next two would be for losses. So, I think the defense is in a pretty good place right now."
Offense B
After a shaky start, the playbook has opened up and the Pios are resembling the style of the record setting '09 season.
Junior Waylon Young stepped in at QB for the third game and the offense is back to doing the things they are best at. Stu Cook has regained his big play explosiveness from the backfield and in the slot as a receiver. Logan Venable leads an improving ground game averaging five yards a carry with a breakaway speed burst and Zac D'Aquin can get open deep from anywhere on the field.
Up front, there have been some wrinkles thrown at the line with injuries and illness to battle through, but the ground game has put together late drives when needed, Cook has busted some highlight reel runs and Venable is keeping drives alive with first down runs off the edge. This is a potential "A" over the back half of the season.
""We could have been in the same position we are now, but it would have been a little more of a struggle without the changes," added Cook. "We've moved some guys around up front and they are getting some valuable experience, but if we can ever settle in on six or seven guys for several weeks it will get us where we need to be."
Kicking Game B+
For the most part, kicking has been solid. Zac D'Aquin has taken over the place kicking and his field goal was the margin against St. Louis. He has hit the only two field goals asked to attempt and kickoffs have often found the end zone.
Punter Tyler Melancon averages 38 yards a kick and has four kicks downed inside the twenty.
Both are outstanding, but there has been a blocked punt, some missed extra points and a couple of adventures along the way. Like your sixth grade teacher, this is another area we're picking on for improvement since not everything can be perfect at mid term.
Special Teams - A
We're splitting the returns out of the kicking game because that phase has been outstanding. Luke Bourgeois hasn't broken one for a score yet, but he has been awful close. More importantly, punt and kick returns have kept opponents backed up and kept the Pios in great position on a shortened field. But we want a return TD!
"Hopefully, we'll get one soon," laughed Luke Bourgeois who is averaging 10 yards on punt returns and 28 on kickoffs. "On punts we pick one side and try to get to the wall. If it's not there, you just try to get as many yards as possible up the middle. Our blocking has been getting better and we hope to get one soon."
The Pios will put their scholarly achievements to test at Erath Thursday night in a contest moved from the original Friday date.
Coach Destin Dieterich began his second campaign at Erath with expectations for great improvement. The Bobcats were winless in league play last season and finished 3-7 in a year of change.
Erath opened with wins over Berwick (34-7), Catholic, NI (28-14) and Vermilion Catholic (48-21). Senior tailback Aaron Darby (5-7, 155) was lost to injury early in a week four loss to West St. Mary (23-12) and Erath blew a 19-0 lead in losing to Church Point (27-26) last week.
"They are definitely improved over last year and might be 5-0 had they not lost Darby," explains Cook. "They ran for over 300 yards last week and had a big pass play. Now they will have had another week to adjust to him not being in there."
Erath will spread the ball in their option attack with speedy junior RB Cody Bourque (5-9, 155) and QB Mikey Seymour (5-9, 145, Sr) leading the attack. Seymour rushed for 145 yards last week and Bourque gained 60 on seven carries.
"Offensively, they were moving it on everybody," said Cook. They are aggressive and fly around on defense. They've given up a lot of yards but they are good enough to compliment the offense."
Notre Dame's defensive front and linebackers are spending so much time in opponent backfields that Erath may have more to worry about than their offense.
"From the second quarter on against Eunice, that was probably our most complete game," concludes ND coach Cook. "It's a brand new season and we're all starting over. I'm sure they'll be ready for us and I know we'll be prepared for another tough game."


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LOS ANGELES: We Are Going to Make Music Pasadena!
Please, join us tomorrow at Make Music Pasadena as we showcase our scanning app and hardware!
Make Music Pasadenais a FREE, all-day, all-ages music celebration that attracts an estimated... Read more
OwnPhones is on track, check out some of these updates!
Hi All,
OwnPhones is making huge strides and we want to keep you informed. We can share a few details on our progress which includes new colors and finishes,... Read more
Pre-Orders now available on our website.
Hello supporters!
Did you miss the Kickstarter deadline? Did you back us on Kickstarter and want to order another pair? We got you covered. OwnPhones is now offering Pre-Orders on... Read more
OwnPhones is funded! Thank You!
We are very grateful to announce that OwnPhones has been funded, raising more than 300% of our original goal with a total of $767,472. The success of our campaign... Read more
Last Chance to order your OwnPhones! 4th Stretch Goal Reached!
Spread the Word
Thank You supporters! As our Kickstarter campaign comes to a close, we would like to thank all of you for making OwnPhones possible! We want to make... Read more
OwnPhones has a new Stretch Goal!
Next Stretch Goal
OwnErgonomics $700,000
OwnErgonomics will offer the active user an even better secure fit. This stretch goal will allow us to perform more motion-capture and bio-mechanical analysis in... Read more
OwnPhones on FOX Business News and stretch goal update!
OwnPhones was featured on FOX Business News yesterday! The continued success of our Kickstarter campaign has brought national recognition made possible by our supporters; again, we would like to thank... Read more
OwnPhones is on CNBC's "Tech Crowd" and we need your votes!
OwnPhones is featured on CNBC's "Tech Crowd" Competition!
We are featured on CNBC's "Tech Crowd" and need your help. Vote for us so we can move to the next round... Read more
OwnPhones has doubled its funding goal & reached its first 2 stretch goals! Watch us on CNBC!
We have reached our second stretch goal!
Charging Case: $450,000
Charge your OwnPhones on-the-go. Charge the case once and you can charge your earbuds 4 times before you have to... Read more
OwnPhones has reached its first Stretch Goal! Next stop, charging case!
We have reached our first stretch goal!
The OwnPhones app will be available for Windows phone which lets you control all SmartFit advanced features including SoundScaping, Real World Notification and... Read more


text:
Michael Salmonowicz
The Report Card
My Stats
|Contributor since:
|September 2009
|Chicago, IL
About Me
I'm a Teach For America alum and spent three years as a high school teacher on the west and south sides of Chicago. I've conducted research on turnaround schools with a team from the University of Virginia, consulted for school districts across the country, and done work with New Leaders for New Schools, the Consortium on Chicago School Research, and DonorsChoose.org. Currently I'm finishing my PhD from UVa's Curry School of Education.
My work has been published in Education Week, the Phi Delta Kappan, and a number of academic journals, and I'm a co-author of the book Teachers' Guide to School Turnarounds. I also contribute monthly to GOOD, the website "for people who give a damn": www.good.is/community/MichaelSalmonowicz
Learn more about my writing: http://sites.google.com/site/salmonowiczpubs
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text:
The student-led start-up ZenKars sounds as if it should have emerged from Southern California. After all, its goal is to provide used-car shoppers with a "peaceful buying experience."
But ZenKars is Philadelphia-born and bred, and it won the 2013 Wharton Business Plan Competition last week.
ZenKars is an online retailer of used cars that doesn't have a weedy lot filled with cream puffs. According to
a YouTube video of its presentation
at DreamIt's Demo Day in December, the company connects car buyers directly with commercial sellers that typically shed their fleets via the auction process.


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Dr. Mitch can only provide general medical insights. He cannot counsel you on your own particular case. Information about a specific individual's medical condition can only properly be managed by a health care professional who has examined that person and done a proper evaluation. Furthermore, Dr. Mitch will not be able to respond to individual requests for referral or diagnosis or management or to provide a second opinion. His intent is to help people know more about medicine and science so that they can ask their health care professional the right questions and make more informed decisions with respect to their health. You should consult with your health care professional before following any of Dr. Mitch's advice to confirm that it is appropriate for you.
Drug shortages are in the news again. This is not a new problem and it`s not going to be resolved any time soon. It`s not an issue limited to Canada and it`s not specific just to people, as veterinarians are affected also. And it`s not an issue of generic vs branded drugs. A number of factors have created this recurring ``perfect storm``.
To save on cost, all pharmaceutical companies (generic and branded) have concentrated their manufacturing. A single site now makes the world-wide supply of a number of different products. Thus a problem at one plant can shut out many different products for the entire world. Not only must the issue be resolved but the plant must then be certified by the appropriate regulatory agency, a process that can take months.
Next, raw materials for almost all of our drugs come from a few places. India and China play pre-eminent roles. Recently the head of the American FDA travelled to India to deal with quality control issues there. There has been pushback because of the increased cost this will entail. China has been very resistant to outside intervention.
To add to the problem, large amounts of drugs aren`t stockpiled to save on inventory costs. If there`s a hiccup anywhere in the supply chain, there may not be reserves available.
What can you do about this?
Often we have safe substitutes. It`s not optimal to change from a drug your body has gotten used to but it can be done safely. Pharmacists have been doing an incredible job staying on top of this. Unfortunately however in some cases (cancer and some heart rhythm drugs are the examples that spring to mind), we do not have the luxury of equivalent alternatives. That`s a real concern. What you can do is make certain that once you`ve been stabilized on a specific drug you get as much as your drug plan will allow and store it properly.
The Bigger Solution
This is definitely a situation that demands a coordinated effort across borders (perhaps under the auspices of the World Health Organization). The suppliers of raw material need to be inspected regularly and forced to conform to standards of purity that are universal. Pharmaceutical companies are already working together with wholesalers and within their own organizations to deal with supply chain and stockpiling issues and drugs could be moved from one country to another if supplies are available. Here`s where the Federal government needs to play a role as they regulate importation. Essential medications which do not have alternatives should be stockpiled to meet reasonable emergency needs.
Perhaps now you can see why this is not a simple issue and unfortunately, why it`s not likely to be resolved any time soon!
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Where Did Lehman's London Stars End Up?
Matt Turner, of Financial News, reports:
Two years ago today, Lehman's European staff arrived at work unsure whether they had a job, leading headhunters to set up makeshift offices in Canary Wharf. In the weeks following the collapse of Lehman Brothers, Financial News spoke to analysts, headhunters and rivals to try to assess the opportunities that might arise for Lehman staffers. Below are some of those identified then as being in demand and information on what they are doing now. The titles given are those held when Lehman filed for bankruptcy two years ago.
–Riccardo Banchetti, co-chief executive, Europe and the Middle East
Along with Christian Meissner, Banchetti was promoted to co-chief of Lehman's business days before its demise. Before his promotion to succeed Jeremy Isaacs on Sept. 8, 2008, Banchetti ran Lehman's Italian business. In the spring of 2009, he set up boutique advisory firm Pactum Advisers, which specializes in advising Italian businesses on unwinding damaging debt and derivatives trades, alongside former colleague Antonio Miele.
–Alexis de Rosnay, co-head of European investment banking
A high-energy banker like William Vereker (see below), de Rosnay was brought in by Lehman to build the bank's fledgling health-care business. In October 2008, Lazard confirmed it had hired de Rosnay as vice-chairman of its investment banking business. He soon proved his worth, leading the Lazard team advising U.K. pharmaceutical concern GlaxoSmithKline on its acquisition of U.S. skincare business Stiefel Laboratories.
–Philip Lynch, managing director, chief executive, Middle East and North Africa
A Lehman lifer, Lynch began as an analyst in New York in 1987. He relocated to Dubai in 2008 to run its fledgling Middle East operation. He now is chief executive officer for Asia ex-Japan and Middle East at Nomura Holdings.
–William Vereker, co-head of European investment banking
Described as a "banker's banker" by his fiercest rivals, Vereker is acknowledged as one of the best energy and power banker in the business. This year, he was named global co-head of investment banking of Nomura based in London, having previously headed the business in EMEA.
–Richard Atterbury, managing director, global co-head of financial sponsors, co-head of global finance, Europe and the Middle East
Hiring Atterbury in 2005 was a statement of intent from Lehman as he was regarded as one of the best financial sponsor bankers in the business. He was chairman of Nomura's financial-sponsor coverage in EMEA until June 2009, and in June joined structured finance boutique Agfe.
–Michael Bonacker, co-head of European FIG investment banking; co-head of investment banking, Germany
Lehman handed Bonacker joint responsibility with Giles Harrison for FIG in addition to his management of the bank's German business in July 2007. While Harrison has joined HSBC as global co-head of FIG, based in New York, Bonacker joined Germany's Commerzbank as head of group development and strategy.
–Adrian Fisk, head of consumer mergers and acquisitions, Europe
Following the retirement of Ludovico del Balzo in 2007, Fisk became Lehman's top M&A banker in the consumer sector. He is now co-head of M&A for EMEA at Nomura, alongside Andrew McNaught.
–Nicholas Jordan, head of investment banking, Russia, central and eastern Europe
Jordan was Lehman's trophy hire when it relaunched its Russian operation in Moscow after an eight-year absence in April 2007. This June, Jordan was named chief executive for Russia at UBS, having been passed over by Nomura for the top job in Russia in April 2009. He left Nomura later in 2009.
–Adrian Mee, managing director, head of mergers and acquisitions, Europe and the Middle East
Mee became the eighth former Morgan Stanley managing director to move to Lehman in 2006 when it accelerated the expansion of its European investment banking business. Last week, he quit his role as head of M&A for Europe and the Middle East at Nomura, following Christian Meissner to Bank of America Merrill Lynch, where he will head international M&A.
–Antonin Baladi, executive director, media group
Baladi joined Lehman's media group from Credit Suisse and until the bank's collapse had been set to join the ranks of its managing directors. He now works at Nomura in the TMT investment-banking group.
–Paolo Cicchine, executive director health-care group
Cicchine joined Lehman's health-care investment banking group in 2007 from Dresdner Kleinwort. He now works at Nomura in health-care investment banking.
–Scott Ferguson, co-head of European equity capital markets
Ferguson joined Lehman from Citigroup as a managing director in 2004, as then head of equity capital markets Philip Lynch pushed forward with ambitious plans to expand the business. Two years later he was promoted along with Ken Brown to replace Lynch as the head of Lehman's European ECM business. While Brown is now global head of ECM at Nomura, Ferguson has been named head of investment banking for the Middle East.
–Matthew Grinnell, co-head of European financial sponsors
Grinnell was promoted to co-head of Lehman's European financial-sponsors team in 2008, having moved to the bank's London office two and a half years earlier from New York. After a stint at Nomura, he joined Barclays Captial as managing director, head of financial sponsors, EMEA.
–Frédéric Legmann, senior executive director financial-institutions group
Legmann joined Lehman almost exactly a year before its collapse and was to be promoted to managing director in November 2008. He joined Lazard as a managing director with a focus on pan-European deals in the financial institutions space. He joined BNP Paribas as head of FIG for Europe this month.
–Mandy Mannix, global head of capital solutions
Mannix joined Lehman in 2003 after more than 11 years at Merrill Lynch Investment Managers, where she worked in its alternative investment group, responsible for hedge fund education for institutional investors and marketing its hedge fund products. She was global head of capital introductions at Nomura until recently, when she joined hedge fund CQS as a member of its executive committee, responsible for sales and marketing.
–Saba Nazar, co-head European financial-sponsors group
Nazar joined Lehman in February 2005, and in July 2008 was promoted to the role of co-head of European financial sponsors. She now works at Nomura in London as global co-head of sponsors.
–Luca Tassan, executive director, head of corporate and infrastructure acquisitions financing
Tassan joined Lehman in 2007 from Royal Bank of Scotland Group, where he was a senior director in structured capital finance for two and a half years. He now works at Nomura in the corporate and acquisition finance banking group.


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CHARLES TOWN - The 34th annual Mountain State Apple Harvest Festival officially kicked off Thursday night with an evening of glitz and glamour during its annual opening Royal Gala.
Hosted by Hollywood Casino at Charles Town Races, the theme for this year's gala was "Hooray for Hollywood," and featured an elegant event replicating an Academy Awards ceremony, complete with replica Oscar statutes and a Royal Gala Academy Chapman Awards ceremony for festival supporters, board members, sponsors and volunteers.
"It's certainly a huge success. It's one of the largest that we've had and we're looking forward to the celebration next year for the 35th anniversary of the festival," said Gala Chairperson Mary Ruth Langdon.
Article Photos
Journal photo by Edward Marshall
Queen Pomona XXXIII, Alivia Ayers, left, and Queen Pomona XXXIV, Lauren McKenzie Linton, pose during the 34th Mountain State Apple Harvest Festival's opening Royal Gala on Thursday night at Hollywood Casino at Charles Town Races.
In addition to the awards ceremony and banquet, the event featured the annual Maid Pomona Race, presentation of the award for this year's Honored West Virginian Gilbert Benton Miller and the introduction of Maid Pomona XXXIV Lauren McKenzie Linton and her court.
Martha Anne McIntosh brought greetings from Sen. Joe Manchin, D-W.Va, and said it was an honor to welcome those in attendance to the annual Royal Gala.
"I congratulate all of you on marking the 34th year of the Mountain State Apple Harvest Festival. I am so proud of this tradition in the Eastern Panhandle. I thank all of this year's organizers, board of directors, countless volunteers and the many sponsors who have dedicated their time, energy and resources," McIntosh said on behalf of Manchin.
McIntosh said the popular festival plays an important role in the region's economy.
"In addition, the event has something for all ages to enjoy. Through many annual fairs and festivals and various other annual events, West Virginia residents keep our unique history and rich Appalachian culture alive and well," McIntosh said.
Another honored guest Thursday was Joy Lewis, regional representative for West Virginia Gov. Earl Ray Tomblin, who also brought greetings on behalf of the governor. Lewis herself is a former Queen Pomona.
"Every time I see an apple, I'll always think of this weekend. It's been 23 years and that's the truth. I love every minute of my time here. I remember so much of it, and I know you are going to have a wonderful, wonderful time," Lewis said.
Reading greetings from the governor, Lewis said Tomblin thanked everyone involved in the making the festival possible.
"From pie-making contests and the festival parade to the delightful arts and crafts, there's truly something for every one to enjoy. These special attractions keep people coming back to our state year after year, and I thank you for that. On behalf of the citizens of the mountain state, I offer my sincere best wishes and I have no doubt the gala will truly will be a wonderful experience for one and all," Lewis said.
Before the night ended, Queen Pomona XXXIII Alivia Lauren Ayers gave a farewell address and thanked everyone involved in the festival.
"It's hard to believe that the Apple Harvest Festival is already here, and I'm so excited for the rest of the weekend's events to unfold. Looking around at this glamorous Hollywood set, I can already tell that you board members have already out done yourselves again," said Ayers. "Court members, get ready to experience a truly remarkable weekend that will not be soon forgotten. I can honestly say that my Apple Harvest weekend was the best weekend of my life. It's an extraordinary weekend filled with great memories that will be cherished forever."
The Mountain State Apple Harvest Festival lasts through Sunday. For a detailed schedule of events, visit www.msahf.com.
- Staff writer Edward Marshall can be reached at 304-263-8931, ext. 182.


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Hello LinuxCandy visitors, wish you happy new year and a great 2012 year ahead !, 2011 was the year of Android. A little over a year ago Andy Rubin tweeted that 300,000 Android devices were being activated each day. According to some reports Android had surpassed iOS in terms of US smartphone market share. In June Android's activations-per-day reached 500,000; this month they hit 700,000. That's more than double the rate at which it was spreading when it overtook iOS.
Already in last articles I mentioned that android is getting into embedded systems, because of that advantage now "Android @ home" new concept is coming out!.
Start with some new android buzz in the world
>>Android siri app hitting on android market
>>Install / Flash CyanogenMod 9 Trebuchet Launcher On Android 4.0.3 ICS
>>What to Watch from Five Tech Giants in 2012?
>>Android 'Jelly Bean' comes after Ice Cream Sandwich (update) later 2012.
Google has just unveiled the Android@Home framework, a set of protocols for controlling light switches, alarm clocks and other home appliances through any Android device.
Ever dreamed of turning lights on and off with your Android smartphone?Want more Android in your house? How about Android in your house. Google wants to think of "every appliance in your home" as a potential accessory for your phone. The team teased ideas like lights turning on and off based on calendar events, applications talking to washing machines, games automatically adjusting for mood lighting, and basically little green dudes taking care of all the menial duties in your house.
At the google I/O event, Google said that it had partnered with LightingScience to launch Android@Home LED lightbulbs by the end of 2011. I've been waiting patiently since then, scowling each time I had to get up out of bed to flick off one of my 'dumb' lightbulbs when I should have been able to simply tap a button on my phone. Chuck out this video
Google provided ADK(Android Open Accessory Development Kit) which contains Android 3.1 platform (also backported to Android 2.3.4) introduces Android Open Accessory support, which allows external USB hardware (an Android USB accessory) to interact with an Android-powered device in a special "accessory" mode. When an Android-powered powered device is in accessory mode, the connected accessory acts as the USB host (powers the bus and enumerates devices) and the Android-powered device acts as the USB device. Android USB accessories are specifically designed to attach to Android-powered devices and adhere to a simple protocol (Android accessory protocol) that allows them to detect Android-powered devices that support accessory mode. Accessories must also provide 500mA at 5V for charging power. Many previously released Android-powered devices are only capable of acting as a USB device and cannot initiate connections with external USB devices. Android Open Accessory support overcomes this limitation and allows you to build accessories that can interact with an assortment of Android-powered devices by allowing the accessory to initiate the connection. All this ADK is based on Arduino.
The Android bulb – a networked LED bulb coming out later this year from Google and Lighting Science will connect to Android phones and other devices through the 6LowPAN mentioned standard, according to Ted Russ, chief business development officer for the company.NXP Semiconductor, other sources have said, will supply the chips for the bulbs. It figures. NXP — which was spun out of the Philips conglomerate a few years ago — supplies low-powered NFC (near field communications) chips to Android phone makers already and is a leading expert in energy-efficient, light-bandwidth communications. NXP also announced a component family, called GreenChip, for LED bulbs based around the standard back in May, a few days after Google and Lighting Science announced the Android bulb. JenNet-IP, an open-source software stack, complements GreenChip. TCP, a light manufacturer, already supports GreenChip.
Next-gen lighting technology has come a long way since 'The Clapper – Google' and Lighting Science Group's new bulb is based on Lighting Science Group's A19 LED light and it features a built-in radio that interfaces with Google's new open-source wireless protocol. Unveiled today at the I/O developer conference in San Francisco, the protocol can be used to control appliances and thermostats as well, so it may very well usher in a new wave of smart systems that self-adjust to ensure energy efficiency.
So bottom line is clear Android @ Home Will Turn Your House Into a Giant, Automated Smartbox. Who knows, may be end of this 2012 while coming back home you having one app in you android phone such that you can open your home-gate,door by pushing patterns in your mobile!!!also on your home lightings by your mobile!!
Link or developers to start with ADK:http://goo.gl/Ab7pK
Hopefully I will try to put Android game development article on my next post!


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UNECE Transport Project Meetings Adopt Innsbruck Initiative
27 April 2010: National coordinators for the Trans-European Motorway (TEM) and Trans-European Railway (TER) projects from 13 countries in Central and Eastern Europe and the Caucasus adopted the "Innsbruck Initiative for safe, secure, prosperous and environmentally friendly transport" on 23 April 2010.
The Initiative was adopted during the 53rd session of the TEM Steering Committee and the 28th session of the TER Steering Committee, held at a joint project meeting from 19-23 April 2010, in Innsbruck, Austria, under the auspices of the UN Economic Commission for Europe (UNECE), which executes both projects. The Initiative focuses on achieving, among others, transport infrastructure enhancing environmental performance, including the realization of clean and efficient public transport, intermodal connections and infrastructure for environmentally friendly transport; and the wide introduction and development of Intelligent Transport Systems (ITS), especially those that contribute to minimizing traffic congestion and air pollution. The Initiative is expected to contribute to sustainable mobility and combating climate change.
The next meeting of the Innsbruck Initiative, which will review progress made, new activities and programmes, as well as plans for 2011, will be held in Vienna, Austria, in November 2010. [UNECE Press Release] [Projects Website]


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A trade group says Facebook needs 'measurement transparency'
The call for an audit of Facebook's metrics comes a week after the social network acknowledged inflating its video metrics.
A trade group says Facebook needs 'measurement transparency'
The call for an audit of Facebook's metrics comes a week after the social network acknowledged inflating its video metrics.
Google bolsters its ad targeting and analytics tools
The tools build on the vast amount of information Google knows about consumers.
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Sponsored by 2013 Social Media 300
People use social media to browse, to get inspiration, and, increasingly to buy. And when they buy, they buy big.
With 80% of U.S. adults shopping online these days, e-commerce has undoubtedly transformed shopping habits, fueled disruptive companies and changed the world.
With the rise of social media, social commerce—e-commerce that involves social media—has exploded, with Facebook and Pinterest leading the way. But is social traffic valuable and hence worth the investment by e-commerce companies? We say a qualified yes. In sampling revenue data from some of the e-commerce sites that Science has incubated, we discovered that the value of each social traffic transaction is higher than that of e-mail and search traffic.
E-mail and search outperformed social in conversion and yield (revenue/visit), with our results similar to a report from web marketing firm Monetate, which came in at .59% for social compared to 4.25% and 2.49% for e-mail and search in the second quarter of 2012. However, the value of social was greater. Social has about a $10 edge on e-mail and more than $25 in search (40% and 250% respectively!).
We also discovered that some social media sites are better than others at converting social traffic into monetary transactions. Comparing Facebook to Pinterest, the two largest social media sites to date, the driver of higher transaction value is Pinterest.
Pinterest has captured a lot of media attention recently as a driver of traffic to e-commerce sites. BizRate's study revealed that 70% of Pinterest users use the site to "get inspiration on what to buy." Monetate found that referral traffic from Pinterest was up 2535% year over year and now makes 26% of all social traffic, compared to to 1% at the end of 2011.
The hype is deserved, to a certain degree. Pinterest's conversion rate, as per our data, is the lowest across all traffic sources. Despite having the lowest conversion, it has the highest revenue/transaction, $54.09, almost 5x that of search and more than double that of e-mail and even Facebook.
Optimizing Pinterest referrals can bring in valuable customers. So while the excitement over Pinterest has yet to turn into high yields, there is real potential for Pinterest to be a valuable marketing tool for e-commerce businesses.
Search and e-mail traffic remain dominant but social traffic must be a key part of any future e-commerce strategy. People use social media to browse, to get inspiration, and, increasingly to buy. And when they buy, they buy big.
Research for this blog was by Alex Osborne, an associate at Science Inc.
Science Inc., based in Santa Monica, CA, creates, invests in and develops technology startups and transforms later-state Internet companies. Its e-commerce companies include Dollar Shave Club, Wittlebee, Uncovet, FourthandGrand, TripleThread and Ellie.
Michael Jones is a long-time Internet entrepreneur and former CEO of MySpace.
Did you know that there are already 273 million Halloween Pins on Pinterest?
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Changes to Google's ranking scheme puts more emphasis on serving mobile shoppers well. Links and ...
Posted 09/29/16
They want mobile shopping to be easy, are open to trying buying on social networks ...
Posted 09/27/16
The signals consumers use as they navigate the web can help brands design, launch and ...
Posted 09/27/16
Online retail is hard, grocery retail is really hard, so online grocery is, of course, really, really hard."


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"Essentially, it is the story of Theseus and Ariadne: Theseus in the labyrinth, Ariadne cuts off the thread and there he sits. And the labyrinth […] is the political German Catholicism" [Böll, Victor and Renate Matthaei (eds.), Querschnitte: Aus Interview, Aufsätzen und Reden von Heinrich Böll (Köln: Kiepenheuer & Witsch, 1977), pp. 116-17. My translation]. With these words Böll circumscribes the basic plot of Ansichten eines Clowns [The Clown, 1963], the author's first fictional work to become a bestseller. Böll re-casts this Greek myth to provide the framework for a multidimensional narrative. Ansichten eines Clowns is a love story, …
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Mundt, Hannelore G.. "Ansichten eines Clowns". The Literary Encyclopedia. First published 13 January 2009
[http://www.litencyc.com/php/sworks.php?rec=true&UID=11633, accessed 25 September 2016.]


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BLOSSBURG - At a special Southern Tioga School District board meeting, Dorothy Norman, of Liberty, told the board that she said was not "cold hearted" because she "hates to see any school close," but that the district should be held "legally responsible" should the board decide to go through with the North Penn building project.
"I feel like a mother scolding her kids as I write this, but it sums up how I have felt the last two years about this cart before the horse kind of thing," she said.
Because, she said, the district has shown "irresponsibility in sound fiscal management, past and present" the administration should be held "legally responsible."
She further stated that the board and administration had failed to manage and coordinate high school academics and is not "addressing education as a priority."
"The district has declared insufficient funding and thereby cuts ... the arts, which provide lifelong amenities, and (has) not been able to coordinate cost cutting other than combining sports programs," she said.
She called on the board to "halt any drastic changes being considered "as there has been "no proof of improved scholastic achievement or financial stability offered."
"If consolidation is the only way to rectify the fiscal mistakes of the past, with common sense, and with an educated plan, we can proceed with some form of consolidation on a site more suitable and accommodating than the one proposed, or we will fail as educators and role models for our students and communities," she said.
Harry Gerrish, of Liberty, asked Superintendent Keith Yarger if the board would know how much it would cost to retrofit Liberty High School for elementary school students before it accepted bids to do the $20 million North Penn project, and Yarger responded affirmatively but could not say how much it would cost.
Sean Bartlett, of Richmond Township, told the board "whatever is ultimately selected, the devil is in the details, if it is not well thought out, it almost always costs more than expected, and frequently it fails. We've not seen a lot of detail publicly. The reality is systems only succeed if you have the buy-in of the people involved and here you have parents and teachers who feel disenfranchised and not involved and if you don't have their buy-in, it will fail."
The bids for the North Penn project came in slightly lower than the first time it was bid, but the board took no action Monday.
Quad 3 architect Sam Scarantino presented the low bids only to the board, which he said totaled about $56,000 lower than the first go round several months ago.
According to Scarantino, the total low bid the first time, which includes general construction, roofing, electrical, plumbing, heating and air condition, food service and fire protection, was $17.46 million. The low bid this time was $17.41 million.
Among the bids this time were for general construction, J.C. Orenson, $9.4 million; roofing, T.G. Corp., $1.4 million; plumbing and heating and air conditioning, Silvertip Inc., $1.25 million and $28 million; electrical, Lecce Inc., food service, 11400 Inc., $313,400, an increase of $145,000; and fire protection, Triangle Fire Protection, $540,000, an increase of $126,000.
The bids that increased likely did so because the bidders were the only ones to bid, Scarantino said.
Superintendent Keith Yarger asked anyone making comments to provide them in writing either via mail or email at email@example.com so they could be added to the hearing comments. The deadline for receiving public comment on the project is Oct. 4, he reminded those in attendance.


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Welcome to Glock Talk
Why should YOU join our Glock forum?
- Converse with other Glock Enthusiasts
- Learn about the latest hunting products
- Becoming a member is FREE and EASY
If you consider yourself a beginner or an avid shooter, the Glock Talk community is your place to discuss self defense, concealed carry, reloading, target shooting, and all things Glock.
Can W296 or Hodgdon Lil'Gun be used in a 10mm???
Discussion in 'Reloading' started by Tmygun, Jan 26, 2010.


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Created in this Craftsy class
Craftsy Block of the Month 2012 taught by Amy Gibson
In Craftsy's first-ever Block of the Month, Amy Gibson brings you 10 specific quilting techniques - appliqué, string quilting, paper piecing and more.
Other projects made as part of this class:
QuiltingPurple Plum
QuiltingQuilt class from Amy Gibson
QuiltingMy first Quilt
Offer some kudos...
Join the conversation...
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Your colors make me feel that this is upside down! Or is it?
06/03/2012 Flag
Well the colours are so soft that I wondered if I was looking at the back of the block. Nice job. I should see your other blocks too.
Totally cute fabric! Love the little cars!
I just had to have a closer look at your other blocks... The prints in the fabrics are delightful! Very subtle. I imagine some lucky child would love a quilt made with these blocks!


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Article Title:
800 MHz Public Safety Interference: The Consensus Plan
Harlin R. McEwen, Chief of Police (Ret.), Ithaca, New York, and Chair, IACP Communications and Technology Committee
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September 2003
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