text:
Texas' tortuous journey through the Legislature's most partisan exercise is over, but probably will not be long forgotten.
The Senate vote Sunday on a new plan to redraw the state's 32 congressional districts ended with a 17-14 decision.
The hard truth of the final product, though, is that lawmakers have shafted the Panhandle.
They did so by approving an alignment that splits Deaf Smith County out of the 13th Congressional District while producing a horribly gerrymandered 19th Congressional District.
The result of this hatchet job is to reduce the Panhandle's clout in Congress while giving Republicans a shot at gaining as many as six additional seats in the Texas congressional delegation.
What about the much-touted Panhandle legislative solidarity?
It vaporized.
Rep. John Smithee, R-Amarillo, whose legislative district was most affected by the switch, voted against the plan in the House, as did Rep. Warren Chisum, R-Pampa. Rep. David Swinford, R-Dumas, along with Sens. Teel Bivins, R-Amarillo and Bob Duncan, R-Lubbock, voted in favor of the plan.
Thank you very much, ladies and gentlemen of the legislative Republican leadership.
It is understandable that lawmakers didn't want to return for a fourth special session. Moreover, everyone involved in this process recognizes the political back-stabbing that always occurs during redistricting.
But this attempt to redraw the lines, forced upon legislators by the likes of U.S. Rep. Tom DeLay, was particularly brutal, partisan and unforgiving.
The fight is over. The Legislature has adjourned and its 181 members have returned to their districts to take a breather, resume their day jobs and - one should hope - answer questions about whether this exercise was worth all the trouble.
© 2016. All Rights Reserved. | Contact Us


text:
For Women Who Want The Ballerific Life!
'Think Like A Man' has proven itself to be a Box Office hit raking in $33Million in its opening week. The movie is based on Steve Harvey's book "Act Like A Lady, Think Like A Man". In the movie they touch on the infamous 90 Day Rule. This rule has been around long before Steve Harvey's book. The 90 Day Rule basically says that a woman should make a man wait 90 days before having sex. Does this work? Are the "games" really proving anything? I asked my Twitter followers and actually got a pretty good mix of responses.
Ladies, would you make a man wait 90 days for sex?
- yeah cause I may not even like u after 20 days
- I would...I did...waaaay longer than 90 days. We are married now. We were each other's 1st. Met at 17.
- at this point in my life knowing what I know- YES!
- No! That would mean I would have to wait!
Fellas, would you wait 90 days for sex?
- people have waiting much longer you know? you mean do we prefer or would we want too...a nigga will wait years lol we do most of the time...we wait from the moment we see people! lmao
- absolutely not. I can't think of one valid reason to wait 90 days
- I've waited years. More than once. I never really invest time and money just for sex. That's just prolonged prostitution. I'm in it for the person. If they're worth it, I don't really care about the wait. I'll tell you this...I always told my female cousins to stick to that 90 day rule. If he's there for you...he'll wait. If not, better you get rid of him now instead of wasting your time.
- HELLLL NO SON....*in my angriest DMX voice*
- Only if I was getting some from somewhere else instead..
So if we think like a man for a moment it looks like some men will wait, some men will not. I won't tell you who these answers are from but these are all seemingly good guys. Some of which are married, some have been in pretty long relationships. Although the answer from women varied like the men, it seems that more of us would wait. Here are my thoughts on waiting.
The whole strategic game thing is a load of b*******. Women weren't built to think like men. Every time we try, we over think. You know why? Because men are far less complex than we are. If a man says he's cold, he really is cold. When a woman says she's cold, she really wants you to take the jacket off your back and give it to her. There's no way that we can fix our complex minds to think like a simple man. We shouldn't have to. We're built different for a reason, to compliment each other. Why would you make a man wait 90 days for sex? I say you don't have sex until YOU are ready. There's no time stamp on that. If you know you're ready to have sex with someone within 90 seconds, go ahead and do it! We're all adults. If it takes you 90 years, do you! Two people should not have sex until they're ready. Making him wait 90 days when you knew 89 days ago that you'd let him hit, all because Steve Harvey said so, is dumb. Him waiting 90 days doesn't mean that he's a great guy and you'll be together forever. Sleeping with a man after the second time doesn't mean he only wants you for the sex. Building a meaningful relationship has everything to do with communication, period. I think women should Think Like Women. If a man wants someone who thinks like him, he's more interested in peen than you. If a man is really into you, he'll make it loud and clear, whether sex is involved or not. There is no shortage of vagina in the world. Steve Harvey makes great points in the video below, but I'm not buying that it's at all that easy.
Views: 28353
Just curious does the 90 rule and thinking like a man, acting like a lady apply to male-on-male relationships?
Anyway....Everyone is on their best behavior during the beginning of a real courtship, no one is their "true self" we all send in representatives who try to be on our best behavior. So say said male is doing almost everything right in those first 90 days, this still doesn't prevent the inevitable, that you get caught up, he changes, & your feelings get hurt, there's no way around that, it's life. True without the complication of sex, you're more aware, but it'll still happen. So I don't see the "Gospel" in the 90-Day rule. Women are usually good judges of character, we know what kind of man Eric from accounting is, we just choose to overlook those not so good qualities, that later come to bite us in the ass. I will agree with Steve in saying we give men WAY TOO much power over us.
Im sorry. I am not and will not take relationship advice from a man who abused his wife and is a damn comedian.
No one is saying that it is guaranteed that he will stay with you if you wait 90 days or more to have sex. I'm saying that if you wait until you know him you might not get got. Not every woman is a good judge of character. If that were true then the book wouldn't have been a best seller, become a movie, and grossed $33 million in its first weekend. Everyone learns to recognize game at a different pace. What I pick up as game in the first 90 seconds of meeting a guy some other chick might not pick up even after 90 days. What is the harm in waiting 90 days anyway? If he is a good man then he'll wait because he knows there are a lot of shiftless azzhole guys out here pretending to be good men. He'll wait until you trust him. If he's just a shiftless azzhole guy you might end up saving yourself some aggravation and mileage on your puzzi.
Hey, to each their own. But if a woman is looking back over her past relationships and seeing that she gets a lot of bums that she didn't find out were bums until they got in her panties then maybe it might be a good idea for her to institute a waiting period. JMHO
Thanks, JM, that's what I was saying succinctly.
LIALG, if you have an orifice for a man to stick his penis in then you will attract shiftless men. Period. Everyone just isn't good at seeing them a mile away like I can. I got a friend now who is so money savvy her and Suze Orman are just sisters from another mother. lol But when it comes to men? Ugh! I want to smack her!
I agree with CC.
I made a guy wait three years to have sex with me he did all the right things after sex I visited him a few times we lived in different cities he was up for a promotion and I was there for him helped him pick out his suit and all...Shortly after he ended things with me and married someone else:-( so ummm no Im not waiting again I had to many feelings for him and was crushed not only did I lose a "lover" I lost a great friend

subset: commoncrawl


text:
With all the technology available today, where are the gas mileage advances?
The automotive industry has given is all kinds of toys and comforts, but no real gas mileage improvements.
They have given us vehicles that back themselves up; heat-seeking technology to tell you there's a deer or animal in front of you at night; technology that lets you know if you are falling asleep at the wheel or crossing the center line; satellite and mapping technology — and let's not forget the phones! Oh boy!
But where are the advances in gas mileage?
My mom has a 1993 Ford Taurus GL. It gets 17 miles per gallon in the city and 27 mpg on the highway. The cost back then was about $12,000
The new 2013 Ford Taurus gets 22 mpg city and 32 mpg highway at a cost of $26,000
Did it really take us 20 years to get an extra five miles per gallon at twice the price?
— DENNIS VASS/Liberty Township


text:
Closed Captioned
Student-Led Discussions
Banish out-of-place outlines, gaps, puckering and wrinkles for good with Terri Hanson's expert guidance on picking the right stabilizer for any project. Find out how to use cutaway stabilizer with sheer and lightweight fabrics, and achieve perfect tension when hooping it with woven fabrics. Discover which stabilizer is a great choice for appliqué, stitch-intensive designs and sturdy fabrics, and which will help you hoop and embroider tricky, bulky or oversized items. Explore the creative possibilities of wash-away stabilizer and learn valuable tips for creating freestanding lace, intricate cutwork and patches. Learn how certain stabilizers can enhance the look of your embroidery and speed up your stitching, with lessons on fusible fleece, fuse-and-stick stabilizers and topping. As a bonus, you'll also receive four exclusive, embroidery-themed designs you can use to practice your new stabilizer skills!
Get to know your instructor, machine embroidery expert Terri Hanson, and gain an overview of the class, which will help you understand when to use different types of stabilizers and how to create embroidery projects that look and feel exactly the way you want them to.
Learn all about various types of stabilizer and why you need them in the first place! Terri explains the pitfalls of working with the wrong type of support (or no stabilizer at all) and shows you the best practices for measuring before hooping. You'll also learn valuable labeling and storage tips that will prevent you from wasting your supplies on the wrong type of fabric.
Cut-away stabilizers are a great choice for a wide range of projects. Terri walks you through various types that are available on the market and things to consider when hooping your designs. You'll also learn helpful removal tips that will prevent you from cutting your fabric, and will save you lots of time.
Tear-away stabilizers are easy to remove, and provide solutions for thick or thin stitch densities. Terri shows you how different styles of tear-away create notably different aesthetics, and demonstrates how to remove both the clean and soft tear-away types without damaging your stitches. You'll also discover the best fabrics to pair with each type.
Sticky stabilizers can be challenging at times, but Terri shows you how to make them more user-friendly. Learn what types are available before trying your hand at preparing, hooping and stitching a sample design. You'll also discover ways to remove any sticky residue from needles and fabric to keep your projects looking pristine.
Water-soluble stabilizers are a perfect choice for freestanding lace and much more! Learn how to work with delicate designs as Terri demonstrates the "do's and don'ts" for using this versatile stabilizer. You'll discover new project ideas and fabric pairing inspiration in addition to gaining pro tips on keeping your projects looking perfect from centers to edges.
Find out why fusible fleece is one of Terri's favorite stabilizers! Learn about the various types of fusible fleece that are available and consider a range of embroidery options, such as trapunto and redwork. Terri shows you how to remove fusible fleece without damaging your fabric, and how it can be useful when creating in-the-hoop designs.
What stabilizer should you use with appliqu�? Terri answers that question and many more as she walks you through methods for using various fuse-and-stick stabilizers. Learn how to carefully adhere your stabilizer to your fabric and cut out your appliqu� pieces. Next, take it to the machine to see how to successfully stitch out your work.
Branch out from stabilizers as you learn about toppings and cloud cover. These valuable tools help make your designs float on top of any fabric while keeping the back sides smooth for wearing comfort. Learn when to use them as you set your stitches up for success.
�Awesome class with great information. Choosing the correct stabilizer is so important and love the tips on storing and labeling.�
- Ontheroad


text:
Jefferson Parish Councilman Louis Congemi said Thursday he has received a request from the federal government for information in the investigation of computer system irregularities at Kenner City Hall.
"We have fully responded to that request," Congemi said in a written statement.Congemi, a former Kenner mayor and City Council member, said the information requested by the government was not related to the separate federal probe of former Parish President Aaron Broussard's administration.
His statement did not indicate whether he is a target of an investigation, or when the records were requested and turned over to the government. He did not return phone calls for comment.
Congemi released the statement six days after two Kenner workers resigned in the face of what city officials said is a criminal investigation. Mason Morris, a senior systems specialist in the Information Technology Department, and Danna Morris, the IT director, both quit Friday.
The Morrises are married, and both had placed on paid administrative leave in early April, City Attorney Keith Conley said.
Danna Morris is Congemi's former council secretary and ex-wife. The two divorced in 2001, during Congemi's tenure as mayor.
Kenner officials said questions about the computer system first surfaced in early February, the same time as the qualifying period for the mayoral race won by Mike Yenni. Kenner's computer consultant was asked to look at the computer system at that point and told officials there were issues that needed to be reviewed, Conley said.
Yenni defeated Phil Capitano for mayor on March 27, in a race that originally included Congemi, who later dropped out.
On April 1, city officials notified the Morrises of the criminal investigation. Two local television stations, WWL and WDSU, have reported that Congemi was subpoened by the FBI as part of the Kenner computer probe. Congemi's attorney, Donald "Chick" Foret, would not comment on the reports.
. . . . . . .
Bob Ross can be reached at email@example.com or 504.883.7053.


text:
The process of buying a new Chevrolet car or truck can seem overwhelming if you don't know where to begin. Edmunds.com can get you started on the right track with a convenient directory of Chevrolet car dealerships in and around Logan, Iowa. Compare online price quotes on the new or used car, truck, SUV, minivan, or wagon of your choice to locate the best deals. Edmunds.com makes it easy to find trusted Chevrolet car dealers in Logan, saving car buyers time and money on what will be an important purchase.
Non Display Review Name "ealership was clean and invinting. all staff were profession and friendly. JR was a great help in going over truck and working with me on accessorie"... Read more Review by: ToddRD


text:
The Joe Barnhart Bee County Library strives to be the learning crossroads of our community and the place to visit for lifelong interest in the discovery of ideas, the joy of reading, and the power of information. Community needs drive our services as we seek to improve the quality of life for all citizens of our community in concert with organizations in and beyond Bee County. We take a personal interest in ensuring that a full range of materials and services are provided in an inviting, convenient, and responsive manner. We especially recognize our responsibility to serve as an instrument for children to explore the world through reading and learn the value of libraries.
• A library card is issued without charge to any resident of the State of Texas, person paying property taxes in Texas or any student attending school in Bee County with proper I.D and proof of residence.
• All library cards must be signed before use.
• Library cards issued to children 17 years or under must be obtained by a parent or guardian who will take responsibility for any library obligations.
• As proof of residence, the Library accepts a valid Texas driver's license or Texas ID, utility or telephone bills, voter registration card, county property tax statement, or a personalized check. Library Staff may substitute alternate proof on a case per case basis.
• Library cards will expire on an annual basis. When the card nears expiration, the patron should stop by the Library with ID described above to renew. Staff will verify residence and update the borrower record to reflect any changes. Any balance pending on the card must be paid prior to renewal.
• A replacement card costs $2.00. The patron is responsible for all items checked out on the card until the card is reported lost.
• Library cards must be presented each time books are checked out.
The Library Board of the Joe Barnhart Bee County Library voted to approve and endorse the following behavior policy proposed for the consideration by the library director:
• The premises include not only the building but also the parking area and lawn of the Joe Barnhart Bee County Library.
• Consumption of alcoholic beverages is prohibited on the premises.
• Use of tobacco products is not permitted in any area of the library building.
• No soliciting of staff or patrons on the library premises.
• No behavior is permitted which is offensive to others using the library.
• No loud talking or other noisy distractions.
• No running on library premises.
• No horseplay on library premises.
• No defacing furniture and fixtures of the library.
• Food or drink is only permitted in assigned areas during specific events.
• Profanity is prohibited.
• Cell phone conversations may only occur outside of the library.
• Firearms are prohibited on library premises.
• Weapons are prohibited on library premises.
• Persons violating these polices will be regarding as trespassers.
Anyone violating the behavior policy will be asked to cease doing so and/or to leave. Before the police will summoned to deal with anyone refusing to leave when requested to do so and any time criminal behavior or acts are observed.
• Minors (17 years of age and younger) must follow the Behavior Policy.
• Minors renewing their library cards must have their responsible party present to validate current phone number and address on their account.
• Children 8 years and under must be accompanied by a parent, legal guardian, or assigned caregiver. The parent/ caregiver must be in the immediate vicinity and in visual contact with the child. The assigned caregiver must be a responsible person and must carry emergency contact information.
• Children from 9-17 years old may be left unattended in the library for only two hours per day. The library may notify the Police regarding any child left beyond the two hours.
• Children under 8 may attend programs longer than 2 hours however the parent/caregiver is expected to remain in the library building and immediately rejoin the child at the end of the program.
• Parent/caregiver are responsible for their children's use of library materials and equipment.
• Children using computers must use their OWN library card for access.
• Children using computers must follow the Computer Use Policy.
• The library may notify the Police regarding any children 8 years old and under left unattended. The responsibility for the safety and behavior of the children in the library rests with the parent/caregiver and not with library staff.
Children, who do not follow the Library policies, will be asked to leave the library and a block may be placed on their library account. If the child refuses to leave, the police may be called.
• Items may be renewed in person, by telephone, or by e-mail (firstname.lastname@example.com).
• Fines are assigned to items renewed after the original due date.
• Videos and other audio visual materials must be returned in person at the Circulation Desk.
• No more than 5 books total, including up to 3 items categorized as New Books may be checked out. Books may be subject to limits during peak subject request.
• Items may not be renewed if another patron has placed a hold on the title.
• New Books may not be renewed.
• Reference books, newspapers, and magazines do not circulate.
|5 total
|3 weeks
|3 per card
|3 weeks
|3 per card
|3 weeks
|3 per card
|1 week
|15 per card
|3 weeks
|New books
|3 per card
|2 weeks
|5 per card
|3 weeks
|subject to availability
Inter-Library Loan (ILL) is a valuable resource to the community and serves as an extension of the library's service. Materials of interest that are not included in the collection may be obtained for the patron through Inter-Library Loan request. The library staff identifies the materials and submits the request to several libraries which may then elect to provide the material. These materials are shipped to the library by mail free of charge, however, the library must pay the return postage (book rate). Due to the costs involved, limits of use must be defined.
In this reciprocal agreement, the Joe Barnhart-Bee County Library provides requested materials to other libraries. Materials on hold for local patrons, recent arrivals, materials earmarked for programs, reference, audio-visual, and special collection materials will not be approved for lending to other libraries.
Request forms are located at the Circulation Desk (lower floor) and the Reference Desk (upper floor).
• ILL requests may not be processed from patrons with outstanding fines.
• Patrons may receive up to three (3) free ILL materials per month. Additional ILL materials requested will be charged return mailing costs.
• Library staff will place telephone calls to the contact number provided on the request form. Connection with an individual or answering machine will serve as a legitimate notification.
• A postcard will be mailed if we don't have a response by phone, machine, or person is hearing impaired.
• ILL materials must be picked-up by the due date or materials will be returned.
• If a patron does not pick up their requested and received ILL item they will lose ILL borrowing privileges.
• Late fees corresponding to regularly circulated items will be applied.
• Excessive late fees (exceeding $5.00) and loss of item(s) will result in suspension of ILL privileges.
• Books and CDs that are returned after the due date are assessed a charge of 10¢ per item per calendar day that the library is open.
• Films (DVDs) are assessed a charge of 50¢ per item per calendar day that the library is open.
• The maximum fine is one-half the cost of the overdue item.
• Processing fees and overdue charges are non-refundable.
• For a lost or defaced item, the price of the item at time of purchase is charged plus a processing fee of $5.00.
• No substitutions will be accepted in lieu of lost or damaged materials.
• Items returned within six months of being paid may have the cost of the item refunded if the original receipt is presented.
• A patron will lose library privileges if the account balance of any associated account exceeds $5 and/or overdue items have not been returned.
• Patrons will receive two written notifications regarding overdue status, the third notice will be referred to the County Attorney for action.
• Items will be considered "lost" after 90 days of due date, or upon receipt of returned overdue notice; the account balance will then only reflect the purchase price of each item plus $5 processing fee.
• Patrons may declare an item lost at any time, thereby accepting the replacement cost and service charge.
• Parents/guardians are responsible for the overdue fines on associated accounts of the minors under their care.
• The Library will decide whether damaged items will be repaired or replaced.
• Details of overdue items and associated charges may only be discussed with the account holder or individual designated in writing by the account holder.
• The only authority of determining overdue status is the circulation computer.
• Patrons have 30 days to pay overdue fines once they have been notified in person; after 30 days their account will be blocked until the fines are resolved.
Audiobook case (multiple)
If the exact cost to replace an item is not listed in library records, the following default charges apply:
|Media Type
|Default Cost
|Maximum Overdue
|Hardback book
Softback book
Interlibrary Loan
Compact disc
Multimedia Item
What the Library
is charged
$20.00 (per disc)
$20.00 (per disc)
What the Library
is charged
$10.00 (per disc)
$10.00 (per disc)
Multimedia items include books with compact discs or computer disks. If one portion of the multimedia is lost the entire item is lost. Example: if a book is returned without its accompanying compact disc then the entire item is declared lost and the patron is responsible for the replacement cost of the entire item.
The Library Board of the Joe Barnhart Bee County Library approved the following computer use policy:
The Library requires that patrons using public AND personal computers do so within the guidelines of acceptable use. Exposing Library staff or patrons to images which may be deemed objectionable or obscene will result in the revocation of Library privileges. Library staff are authorized to terminate any patron's session or revoke a patron's computer privileges if a patron fails to comply with this policy. Illegal acts involving Library resources may also be subject to prosecution by local, state, or federal authorities. Patrons may be given two verbal warnings of unacceptable computer behavior and will then have their privileges revoked after the third incident. Serious violations will result in immediate loss of computer privileges and removal of patron from the premises. A loss of privileges may be reviewed upon written request to the Library Director.
All computer users must comply with local, state, and federal policies and laws, listed or not, related to use of these computers and use of the Internet. Violations including, copyright infringement, downloading pirated materials, displaying obscene images, accessing resources provoking sexual harassment, and child pornography will not be tolerated. These regulations apply to all computer users on the library premises.
• Computer users will observe generally accepted "community standards" in their selection of websites to access.
• Commercial use of public access computers is prohibited.
• Patrons must have their library card, in good standing, in their possession to use computers.
• All patrons must have complete and clear library accounts including associated accounts (no blocks i.e. overdue charges over $5.00, returned check/credit charges, missing information, etc.).
• All public access computers are filtered. This is in accordance with the Children's Internet Protection Act (CIPA).
• Library workstation time usage is limited to 2 hours.
• Time is allotted per library card.
• Patron may not use another patron's access to the computers. If they do, both the patron using the computer and the patron whose card is being used, will be suspended from using the computer for an appropriate length of time.
• Patrons must be seated when using the computer. They may not lean over another patron who is using the computer.
• The Library staff cannot set up electronic mail accounts. If a patron wishes to use this resource, they are responsible for accessing and creating their account independently.
• A Library staff member will assist patrons with computer use as time permits, but cannot offer detailed training or technical support. Patrons needing training will be advised of the next scheduled workshop.
• The Library will offer free workshops to its patrons for their personal use. The Library Director must approve workshops for business or for profit use. Space rental and service fees will apply.
• It is the patron's responsibility to pay for any pages they print. Current printing rates are 20¢ for black and white, 50¢ for color pages per printed side.
• Children 8 years and younger must be accompanied by a parent/guardian while using the Library's computers.
• Parents/guardians are responsible for their children's use of equipment and should monitor their children's selection of viewing material.
• Children must be seated when using the computer. They may not lean over another child who is using the computer.
• Parents/guardians of children under 18 years of age must declare explicit permission for their child to use access the internet.
• In choosing sources to link to, the Library follows generally accepted library practices. Beyond this, we do not monitor or control information accessible through the Internet and do not accept responsibility for its content.
• The Library is not responsible for changes in content of the sources to which we link, or for the content of sources accessed through secondary links.
• Not all sources on the Internet provide accurate, complete, or current information. Users should critically evaluate Internet sources to determine the validity of the information provided.
• Gain unauthorized access to restricted files or networks.
• Obstruct other people's work on the network.
• Access content violating community standards
• Attempt to cause the system performance to be degraded.
• Attempt to alter or damage computer equipment or software.
• Perpetrate any illegal or criminal purpose.
• Operate a business or commercial activity.
• Violate copyright laws or software licensing agreements.
• Install or download any software.
• Use unapproved devices to download software or save programs.
• Use of electronic information networks for any purpose that results in the harassment of other users.
• Destruction of, damage to, or unauthorized alteration of the Library computer equipment, software, or network security procedures.
• Use of electronic information networks in any way that violates a Federal or State or local law.
• Unauthorized duplication of copy protected software or violation of software license agreements.
• Violation of system security.
• Behaving in a manner that is disruptive to others.
Violations will result in loss of computer use privileges and/or banning from the library premises. Unlawful activities will be referred to appropriate legal authorities.
U.S. copyright law (Title 17, U.S. Code) prohibits the unauthorized reproduction of distribution of copyrighted materials, except as permitted by the principles of "fair use". Users may not copy or distribute electronic materials (including electronic mail, text, images, programs, or data) without the explicit permission of the copyright holder. Any responsibility for any consequences of copyright infringement lies with the user; the Library expressly disclaims any liability or responsibility resulting from such use.
The Library expressly disclaims any liability or responsibility arising from access to or use of information obtained through its electronic information systems or any consequences thereof.
The Library reserves the right to update and change this policy at any time without notice.
Created 11.17.2011 reviewed/revised: 03.19.2012


text:
Author Affiliations: Departments of Pathology (Drs Bö and van der Valk), Radiology (Drs Geurts and Barkhof), and Neurology (Dr Polman), MS Center Amsterdam, VU University Medical Center, Amsterdam, the Netherlands; and National Competence Center for Multiple Sclerosis, Department of Neurology, Haukeland University Hospital, University of Bergen, Bergen, Norway (Dr Bö).
Histopathologic studies have shown that subpial cortical demyelination is extensive in chronic multiple sclerosis (MS).
To study whether subpial cortical demyelination in MS is associated with focal or diffuse white matter (WM) pathologic features on magnetic resonance imaging (MR imaging).
Comparison of postmortem MR imaging findings with histopathologic findings.
Brain donations from a general community.
Three patients with MS with extensive cortical demyelination and 3 patients with minor cortical demyelination were selected from an MS autopsy data set. The postmortem MR imaging and histopathologic data of the patients were compared.
Main Outcome Measures
Two observers blinded to the results of each other assessed the presence, extent, and distribution of focal and diffuse pathologic changes in WM by MR imaging and by histopathology.
Extensive subpial demyelination was not associated with a significant increase in the area of focal and diffuse WM pathologic changes as assessed by Luxol fast blue histochemistry or by MR imaging or with the presence or extent of juxtacortical abnormalities on MR imaging.
The lack of association of MS gray matter demyelination with diffuse or focal WM changes indicates that gray matter demyelination in MS occurs largely independent of WM pathologic changes. The extent or distribution of WM abnormalities cannot be used to identify extensive cortical demyelination in the clinical setting.
Multiple sclerosis (MS) is a disease of the central nervous system histopathologically characterized by multifocal areas of myelin, oligodendrocyte, and axonal loss.1 Although MS is regarded as a white matter (WM) disease, gray matter (GM) demyelination has also been described.2- 5 Immunohistochemical studies6- 10 identified widespread subpial cortical demyelination in MS. Subpial lesions were shown to be the most common cortical lesion type; these are grossly underestimated by standard histochemical techniques.6,7 Autopsy studies6,8 indicate that a subgroup of patients with chronic MS has a pattern of general cortical subpial demyelination, with subpial demyelination in all neocortical areas. Other patients with MS have almost as extensive but not generalized subpial changes; we use the term extensive subpial demyelination (ESD) herein to refer to these patterns of MS pathology. Subpial cortical lesions are largely undetectable by standard magnetic resonance imaging (MR imaging) techniques.9,11 Therefore, they are thought to contribute to so-called clinicoradiological dissociation, the poor correlation between pathologic changes observed on MR imaging and clinical deficits.12 The clinical significance of ESD in MS may not be known until MR imaging methods more sensitive to GM demyelination are developed. A clinical correlate may be cognitive dysfunction, which affects approximately 50% of patients with MS.13
Little is known about whether a possible association exists between MR imaging–visible WM abnormalities and ESD. The objective of this study was to investigate whether GM demyelination is related to the extent and distribution of focal and diffuse WM pathologic features as observed on MR imaging and histopathologic examination.
Following the autopsy procedure at the VU University Medical Center, Amsterdam, the Netherlands, 10-mm-thick coronal sections were removed from each brain, immersion fixed for 6 to 12 weeks, and subjected to MR imaging. From 19 patients with MS, 5 to 12 widely scattered brain specimens from these sections, plus 1 full-coronal brain section or 2 half-coronal brain sections, were processed for paraffin embedding.14 The small specimens were selected on the basis of signal intensity changes in WM at postmortem T2-weighted MR imaging, while the full-coronal and half-coronal sections were selected independent of visible pathologic features. This procedure was performed in cooperation with the Netherlands Brain Bank. In total, 178 tissue sections were selected for analysis. On the basis of the results of immunohistochemical myelin staining, the 3 patients with the highest extent and the 3 patients with the lowest extent of cortical demyelination were selected for further study (Table 1).
Standard dual-echo T2-weighted images (repetition time, 2755 milliseconds; echo times, 90 milliseconds [first echo] and 45 milliseconds [second echo]; number of signals acquired, 2; in-plane resolution, 0.5 × 0.5 mm2; and 3-mm section thickness) of the 10-mm brain sections were acquired, using a 1.5-T scanner (Siemens Vision, Erlangen, Germany). Myelin basic protein–stained tissue sections were matched to the postmortem T2-weighted spin-echo images, using a procedure described in detail previously.14,15
Immunolabeling with monoclonal antimyelin antibodies (antimyelin basic protein [Boehringer-Mannheim Biochemica, Mannheim, Germany] and antiproteolipid protein [Serotec, Oxford, England]) was performed using a standard immunohistochemical ABC procedure, as described previously.9 Luxol fast blue histochemistry was performed using standard procedures.
Numbers of juxtacortical, periventricular, and deep WM lesions were scored independently on T2-weighted images and in histopathologic sections. In addition, the percentage areas of WM and GM with high-intensity signal changes were noted. The pathology reader (L.B.) scored the percentage area with complete demyelination using the antimyelin basic protein–stained or antiproteolipid protein–stained tissue sections, as well as the percentage area with diffusely lighter staining in WM using the Luxol fast blue–stained sections. Only the half-hemispheric or full-hemispheric sections were analyzed for the extent of WM and GM demyelination, as these were obtained independent of macroscopically or MR imaging–visible lesions. The GM lesion distribution was classified as mixed WM and GM (type 1), intracortical (type 2), or subpial (type 3).7 The GM and WM areas and the areas of GM and WM demyelination were measured using morphometry software (Scion Image; Scion Corporation, Frederick, Md) on digital images of the tissue sections.
Lesion numbers and percentage areas with pathologic signal scored on the T2-weighted spin-echo images were compared with each other and with the lesion numbers and the percentage of diffuse or focal pathologic areas obtained from the matched histopathologic tissue sections. Clinical data were evaluated in all available medical records by one of us (C.P.); age at onset, MS subtype, and time to Expanded Disability Status Scale score of 6 were assessed. It was noted whether cognitive deficit had been described in the medical records; however, cognitive function had not been systematically assessed in any of the patients studied.
The means of the focal and diffuse WM demyelinated areas were compared between cases with low and high cortical demyelination using nonparametric statistics (Mann-Whitney test [SPSS version 9.0; SPSS Inc, Chicago, Ill]). Statistical analyses were performed, with 2-tailed P <.05 considered statistically significant.
The pattern of demyelination was established by myelin immunohistochemistry on 9 to 11 widely scattered small (approximately 1-2 mm2) brain tissue blocks, plus 1 full-coronal or 2 half-coronal tissue sections, from each patient. In total, 11 large coronal and 60 small tissue blocks were studied. All 3 patients with extensive cortical demyelination had a similar pattern of large subpial MS lesions; in 1 of these patients, subpial demyelination was ubiquitous (Figure 1). Subpial cortical demyelination could only be detected by myelin immunohistochemistry, not by Luxol fast blue histochemistry. The numbers of GM and WM lesions were scored in the full-coronal and half-coronal sections. These tissue sections were from the frontal region (3 specimens from the ESD group and 4 specimens from the non-ESD group) and the parietooccipital regions (2 regions for both groups). The total number of GM lesions was 116 among the 3 patients in the ESD group and 10 among the 3 patients in the non-ESD group. The most frequent cortical lesion type was subpial lesions for both groups, with 96 lesions in the ESD group and 8 lesions in the non-ESD group. The total number of WM lesions was 23 in the ESD group and 8 in the non-ESD group. There was 1 subcortical WM lesion in the ESD group; there were 2 in the non-ESD group.
Adjacent paraffin sections from patient 1 (Table 1) with general cortical subpial demyelination histochemically stained for myelin using the Luxol fast blue (LFB) technique (A) and immunohistochemically stained for proteolipid protein (PLP) (B). With LFB staining, demyelination of periventricular white matter (WM), including the corpus callosum, is readily detectable (A, white arrows). Cortical myelin is largely unstained (A, black arrows). Periventricular lesions are also well delineated by PLP immunohistochemistry (B, white arrows). In cerebral cortex (CTX), all areas have a superficial subpial loss of myelin (B, black arrows); an area of myelin loss is also detected in the putamen (B, arrowhead). At higher magnification, a sharply defined cortical lesion border is visible by PLP immunohistochemistry (B, inset, black arrow); the border is not detectable by LFB staining in an adjacent section (A, inset, black arrow).
Key clinical data are summarized in Table 1. One patient with extensive cortical demyelination (patient 2) had a particularly long disease duration (49 years) and a long time to an Expanded Disability Status Scale score of 6 (42 years); the 2 other patients in the ESD group had disease durations and times to an Expanded Disability Status Scale score of 6 comparable to those of the patients in the non-ESD group. Cognitive problems during at least 1 time point were noted in the medical records for all the patients in the ESD group and for 1 of the patients in the non-ESD group.
The immersion fixed-tissue sections had a low variability of blood and cerebrospinal fluid content in cerebral sulci, giving consistent results on MR imaging. Examination of postmortem MR images revealed no specific pattern of WM abnormalities associated with general or extensive cortical demyelination (Figure 2). The extensive subpial lesions were not visible on MR imaging. The patients with extensive cortical lesions had no increased juxtacortical demyelination on MR imaging (0.1% of the total WM area in both groups [Table 2]). There was no difference in the extent of diffuse WM changes (7.1% in the ESD group vs 7.7% in the non-ESD group). The extent of focal WM lesions was higher in the ESD group than in the non-ESD group (5.3% vs 2.7%); this difference was not statistically significant (P = .28).
Paraffin sections immunohistochemically stained with antiproteolipid protein antibody (A and C) and corresponding T2-weighted magnetic resonance (MR) images from a patient with extensive cortical subpial demyelination (A and B) and from a patient with a low extent of cortical demyelination (C and D). Demyelinated cortical areas are visible by immunohistochemistry (A and C, blue outline) but not by MR imaging (B and D). Sparse white matter demyelination is detected in both patients (A and C, red outline) and is detectable by MR imaging (B and D, arrows).
In this study, the extreme ends of the spectrum of cortical demyelination in chronic MS were selected to identify a possible association with the extent of WM demyelination. The results showed that the presence, distribution, and extent of WM changes were independent of the extent of GM pathologic features. This indicates that there are no major differences in the extent of WM pathologic features on MR imaging that may be used to discriminate patients with ESD in clinical practice.
Other histopathologic studies6,8,10 found no correlation between the extent of GM demyelination and focal WM demyelination in MS. A recent study10 found a correlation between the extent of cortical demyelination and WM inflammation and microglial activation in MS; however, the correlation coefficient was low. The results of our study support the hypothesis that GM demyelination in MS is a process occurring largely independent of WM demyelination. It was reported that a subgroup of patients with MS may have such extensive subpial cortical demyelination that it constitutes a pattern of general cortical subpial demyelination.6,8 This is confirmed in the present study, as subpial demyelination was detected in patient 1 (Table 1 and Figure 1) in all neocortical areas by extensive histopathologic sampling at autopsy. Our data indicate that this may represent one end of a spectrum rather than a distinct subgroup, as other patients having MS with almost as extensive but not general subpial cortical demyelination were identified. Patients with extensive or general cortical demyelination have typical MS WM lesions, indicating that this pathologic pattern represents MS and not a separate disease entity.6
The sensitivity of standard MR imaging methods for subpial lesions is low, approximately 5%.9,11 The present data do not allow any firm conclusions regarding the clinical effects of extensive cortical demyelination, as the group examined is small and the postmortem information collected from nursing homes or primary care physicians was insufficiently detailed. However, in all patients with ESD, cognitive dysfunction had been noted. The question of a possible association between MS cortical demyelination and cognitive dysfunction could be further resolved by prospectively and systematically recording cognitive function in a larger group of brain bank donors or by developing more sensitive MR imaging methods for cortical lesion detection in vivo. The presence and extent of so-called juxtacortical lesions on MR imaging may not be helpful, because it was found in this study that this does not reflect the presence or the extent of superficial cortical demyelination. In previous studies,16- 19 the main MR imaging correlate of cognitive deficit was global atrophy measures, with only a moderate contribution of WM lesion load. Moreover, MR imaging studies20- 22 indicate that cortical atrophy has an effect on cognitive deficit independent of the extent of WM pathologic features. It is unknown whether this effect is due to focal GM lesions or to the effect of diffuse pathologic changes of GM. We are investigating the postmortem application of potentially more sensitive MR imaging methods for the detection of GM lesions, such as high-field MR imaging and the double inversion recovery technique. The absence of a spatial association between intracortical lesions and subcortical WM lesions or an association between the extent of WM demyelination and the extent of GM demyelination indicates that GM lesions are not likely to be caused by neuronal pathologic features secondary to axonal loss within WM lesions.
We show that extensive cortical demyelination in MS is not associated with an increased area of WM focal or diffuse signal abnormalities on MR imaging, nor is it associated with a specific pattern of signal abnormalities on MR imaging. This indicates (1) that the extent of cortical demyelination is largely independent of WM myelin loss and (2) that the extent or pattern of WM changes as assessed by MR imaging cannot aid in the identification of patients with extensive cortical myelin loss in the clinical setting.
Correspondence: Lars Bö, MD, PhD, Department of Pathology, MS Zenter Amsterdam, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, the Netherlands (email@example.com).
Accepted for Publication: May 11, 2006.
Author Contributions:Study concept and design: Bö and Geurts. Acquisition of data: Bö, Geurts, van der Valk, Polman, and Barkhof. Analysis and interpretation of data: Bö and Geurts. Drafting of the manuscript: Bö. Critical revision of the manuscript for important intellectual content: Bö, Geurts, van der Valk, Polman, and Barkhof. Administrative, technical, and material support: Bö and Geurts. Study supervision: Bö, van der Valk, Polman, and Barkhof.
Financial Disclosure: None reported.
Funding/Support: This study was supported by Dutch Foundation Stichting Multiple Sclerosis Research.
Acknowledgment: We thank the Netherlands Brain Bank (coordinator, Rivka Ravid, MD) for providing the material for this study and Christa van Urk for expert technical assistance.
Thank you for submitting a comment on this article. It will be reviewed by JAMA Neurology editors. You will be notified when your comment has been published. Comments should not exceed 500 words of text and 10 references.
Do not submit personal medical questions or information that could identify a specific patient, questions about a particular case, or general inquiries to an author. Only content that has not been published, posted, or submitted elsewhere should be submitted. By submitting this Comment, you and any coauthors transfer copyright to the journal if your Comment is posted.
* = Required Field
Disclosure of Any Conflicts of Interest*
Indicate all relevant conflicts of interest of each author below, including all relevant financial interests, activities, and relationships within the past 3 years including, but not limited to, employment, affiliation, grants or funding, consultancies, honoraria or payment, speakers' bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued. If all authors have none, check "No potential conflicts or relevant financial interests" in the box below. Please also indicate any funding received in support of this work. The information will be posted with your response.
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
The Rational Clinical Examination: Evidence-Based Clinical Diagnosis
Original Article: Does This Patient Have a Torn Meniscus or Ligament of the Knee?
The Rational Clinical Examination: Evidence-Based Clinical Diagnosis
All results at
JAMAevidence.com >
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Need assistance?
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.


text:
The Windsor Community Foundation is accepting applications for a grant it's providing as a result of a recent community survey it conducted.
The WCF's recent online survey contained questions on three needs categories, which were education opportunities, basic needs (nutrition, health and safety) and arts, culture and recreation. A total of 45 percent of the respondents felt the most important of these was basic needs. The primary need indicated in the basic needs category was for emergency assistance, secondary was elderly assistance. Twenty-nine percent of respondents felt education opportunities were most important and 26 percent of respondents thought arts, culture and recreation were the most important needs of the Windsor area.
After discussing the results of the survey including the individual comments, the board decided to focus its attention first in the basic needs category since the majority of respondents thought this was most important.
The WCF grant will support programs that meet the basic needs of individuals, families and communities in the Windsor area. These may include but are not limited to programs in the areas of human services, economic assistance, food security and health. The grant will be awarded to a 501c 3 organization (or equivalent) in the Windsor area.
"As a follow-up to our survey, we are announcing a grant for up to $1,000 to assist to improve the basic needs of the Windsor area," WCF board president Mark Brase said. "The grant application is on our website and applications are due back by the end of April. Our foundation is excited to give back to the community in an effort to improve the basic needs of our citizens. This is the first small step toward many larger grants in the future to help make our great community even better. We know of several nonprofit organizations within our community serving the basic needs and we intend to boost their efforts through this grant assistance program."
The deadline for organizations to apply for the grant is April 30.
"I believe getting the word out on our survey and grant process will really help us with future fundraising efforts," Brase said. "The survey results are in and we are very thankful for all the Windsor folks that took the time to complete the survey. The survey results were analyzed by the Board and are heavily weighted toward improving the basic needs of our community."
All requests should demonstrate community support and in-kind opportunities. Funding decisions will be made approximately six weeks after the grant deadline.


text:
About this Product:Pipeline Three explores the pioneering world of protein-based therapeutics, from novel constructs to enhanced in vivo effects. The pipeline encompasses the state of the art in antibody and recombinant protein therapeutics, and provides a review of next generation therapeutics. The discovery, development and production of therapeutic proteins are also crucial activities in the protein engineering field. Pipeline Four provides the latest science and developments on topics covering all aspects of protein science, discovery, analysis, characterization, development and expression of these valuable and promising therapeutics.
This digital course includes the following tracks:
About this Product:6 Presentations
Over 270 Slides
215 Minutes
Individual Copy: $345
Site License: $1380
Agenda At A Glance:
Creation of a Bacterial Cell Controlled by a Chemically Synthesized GenomeDaniel Gibson, Ph.D., Associate Professor, Synthetic Biology and Bioenergy Department, J. Craig Venter Institute
Recombinant Proteins for Targeting Intracellular Compartments of Cancer CellsWaldemar Debinski, M.D., Ph.D., Director, Brain Tumor Center of Excellence; Head, Section of Tumor Biology, Department of Neurosurgery; Professor of Neurosurgery, Radiation Oncology and Cancer Biology, Wake Forest University Health Sciences, Wake Forest Comprehensive Cancer Center
Significant Enhanced Expression and Solubility of Human Proteins in Escherichia coli by Fusion with Protein S from Myxococcus xanthusMasayori Inouye, Ph.D., Department of Biochemistry, Robert Wood Johnson Medical School
Synthetic Polymers with Antibody-Like Affinity that Function in vitro and in vivoKenneth Shea, Ph.D., Professor, Chemistry and Chemical Engineering, Biological and Materials Science, University of California, Irvine
Membrane Proteins in the Service of Human HealthRobert Stroud, Ph.D., Professor, Biochemistry & Biophysics; Pharmaceutical Chemistry, University of California, San Francisco
High-Speed NMR Analysis of Human Membrane Proteins Expressed by Cell-Free SynthesisSenyon Choe, Ph.D., Professor, Structural Biology Laboratory, Salk Institute & Joint Center for Biosciences
Speaker Biographies:
Dr. Daniel Gibson is an Associate Professor in the Synthetic Genomics department at the J. Craig Venter Institute in Rockville, MD. He had been co-leading the group's effort to synthesize a bacterial cell. Along the way he has pioneered methods that are instrumental to the synthetic biology field including the development of robust protocols for the assembly of overlapping DNA fragments into genome-size pieces. Prior to joining the JCVI, Dan earned his Ph.D. in molecular biology from the University of Southern California. While there, he studied surveillance mechanisms known as "checkpoints", which are significant in our understanding of cancer development. Before earning his Ph.D., he earned his Bachelor's degree in Biological Sciences from the State University of New York at Buffalo. He joined the JCVI in 2004 and is where he began his Post-Doctoral studies.
Dr. Waldemar Debinski is the Director of the Brain Tumor Center of Excellence at the Wake Forest University School of Medicine. He received his Ph.D. from McGill University and his Pd.F. from the NCI/NIH. Dr. Debinski holds several professional memberships, including a membership in the USAMRMC tuberous scierosis research program, a reviewer ad hoc for NIH/Nci specialized programs in excellence, the Prostate Cancer Foundation of Australia, and the Samantha Dickson Brain Tumour Trust. In addition, he has produced over 100 peer-reviewed publications in the field of translational canter research.
Dr. Masayori Inouye, Distinguished Professor at Robert Wood Johnson Medical School, is a leading scientist in the field of molecular biology and biochemistry, who has made a number of important discoveries in life science. He received his Ph.D. at Osaka University, Japan. In 2008, he was appointed as Distinguished Professor and currently is a resident member of the Center for Advanced Biotechnology and Medicine. He is a member of prestigious institutions such as, the American Academy of Arts and Sciences and the American Academy of Microbiology. Dr. Inouye's research has led to significant advances in the fields of protein folding, bacterial stress response and gene regulation. Most notably, he discovered for the first time a new principle of gene regulation by RNA in 1984, which opened an unprecedented avenue for engineering gene expression from bacteria to humans. In addition to RNA-based mRNA interference, he recently made another important discovery that gene expression can be regulated by protein-based mRNA interference by enzymes, mRNA interferases, destroying specific mRNAs in living cells. This finding leads to novel therapeutic method for cancer and AIDS.
Dr. Kenneth Shea is a Professor of Chemistry in the School of Physical Sciences at the University of California, Irvine. He received his Ph.D. from Pennsylvania State University. His research interests include synthetic organic, polymer, and materials chemistry. He has earned a number of academic awards, including Regents Faculty Fellow, School of Physics Sciences Distinguished Teaching Award, NIH Senior International Fellow, Winston Churchill College Overseas Fellow (Cambridge University), Fellow if the American Association for the Advancement of Science, and the Arthur C. Cope Scholar Award.
Dr. Robert Stroud is a Professor of Pharmaceutical Chemistry and Biochemistry & BioPhysics at the University of California, San Francisco. He was the first to discover fundamental mechanisms of transmembrane proteins by 'Aquaporins' at atomic resolution. These included GlpF, AqpZ, the eye lens AQP0, the H2S channel, and the essential glycerol channel of the malaria parasite P.falciparum. He defined the structure and regulatory mechanisms of the ammonia channel AmtB and the 'Rh factors'. He revealed the atomic basis for 'signal sequence' dependant membrane protein synthesis, signaling by EPO (erythropoietin) via its receptors. Stroud also determined the mechanisms of enzyme drug targets thymidylate synthase, HIV protease, HIV integrase, and KSHV protease and used these to facilitate drug discovery for human health.
Dr. Senyon Choe is a Professor at the Structural Biology Laboratory at the Salk Institute in La Jolla, CA. He received his Ph.D. in Biophysics from the University of California, San Francisco and Berkeley. Aside from his position at UCSD, he is currently the founding director of the joint Center for Biosciences in Songdo Korea, as well as a founding scientist of Implenitude, Inc. His research interests include structural and functional studies of macromolecular assembly and recognition related to biology at the membrane interface, in particular, transmembrane signaling in TGF-beta family receptor; ion conductance and permeation, assembly of voltage-gated K channels by computational, x-ray crystallography, biophysical methods and site-specific mutagenesis. In addition, Dr. Choe researches protein engineering and protein therapeutics for developmental and cancer disorders.
About the Conference:CHI's 10th Annual PepTalk event features strong scientific programming comprising fourteen conferences within topic focused pipelines. The four distinct pipelines range from applying protein discovery research, to developing downstream protein expression, characterization, formulation, and production that ultimately leads to clinical applications. This event is designed with you in mind. Stay within a specific pipeline or track hop, and create a custom agenda to meet your research and networking needs.
Download 2017 Brochure
View Conference At-A-Glance
View All Sponsors
View Media Partners
View 2016 Participant list


text:
Aikido as External Art -or- Where's the Chewy Center?
View Single Post
Fred Little
Dojo: NJIT Budokai
Location: State Line NJ/NY
Join Date: Apr 2001
Posts: 630
Re: Aikido as External Art -or- Where's the Chewy Center?
Fred Little wrote:
I did not make any comment about the utility or inutility of scientific inquiry. Any assertion that I did is categorically false.
No. You said that I could not know that he meant to conjoin the two. I can. Because he did. Conjoin the two. In his statement, which put them together. Which is his until somebody shows it isn't, instead of merely hinting darkly at unspoken reasons for doubt.
Together .as mutually necessary correctives to their differing systemic lacks, which is rather different than together as mutually validating.
Fred Little wrote:
With regard to the "compatibility" of metaphorical versus empirical description, I assert that the two modes depend on two utterly different sets of descriptive symbols with utterly different rules of operation and thus, are not directly comparable. ...."compatiblity" or "incompatibility" of metaphorical or empirical descriptions is of less relevance than the possible complementary utility of the descriptions, which is a rather different matter.
Not in this context. I chose the word "compatibility" advisedly for the context of our art: ."compatible" = "capable of existing together in harmony." Comparability is an entirely different thing
So the "not in this context" notwithstanding, you have apparently agreed that "complementary utility" is a valid form of "compatability."
Fred Little wrote:
While Ueshiba is supposed to have reviewed and approved the text, the apparent fact that it was approved with the stipulation that it be distributed only to yudansha may be taken to indicate that the work was intended as an outline or detailed mnemonic of lessons already imparted through oral and kinesthetic instruction, which was regarded as primary.
Actually, he was QUITE explicit in several places in Budo Renshu that certain things that he mentioned going along were only really appropriate for showing through training. This forces the conclusion that things he othwerwise stated therein were appropriate to be given -- and in the form that he was giving them.
To which I will reply simply that you are taking an occasional absence of evidence as an evidence of absence. I am taking a repeated admonition as broadly applicable beyond the specific instances in which it is invoked.
Fred Little wrote:
Thus, not only would the role of the text and drawings be secondary, tertiary, or quaternary, not primary, but I would also suggest that the distribution was restricted because the text might be regarded as misleading to an individual who had not received individual oral and kiinesthetic instruction. To put a fine point on it, my assertion is that it can not be shown that the authorial or editorial intention was to approach the "definite" or "definitive," much less that such an intention was successfully realized.
and your definitive assertion is based a far less foundation than mine in saying that 1) by saying it, he meant it, and 2) by urging one thing and then immediately urging another thing the two things are deemed to be related and compatible.
But "related and compatible" can also be read as "tempering all extreme views regarding either." And that would be more in keeping with both Buddhist and neo-Confucian doctrine which forms the broader context in which all of Ueshiba's statements are embedded.
Fred Little wrote:
Your position that Ueshiba's language was, on the one hand "metaphorical" and on the other hand so "definite" that you can reify that "definite" meaning into a "definitive meaning" is heremeneutically suspect as anything other than a statement of faith.
You misread. Only one part of the statement was metaphorical; the other expressly pointed toward a reified understanding, which was my point. And I am not a "hermeneutical suspect." --- I am "guilty, guilty, guilty..."
As with the previous reference to Buddhist and Neo-Confucian doctrine, here I will invoke basic Taoist doctrine. To the extent that anything becomes "totally x" it inexorably tends toward its obverse and becomes "non-x." This is a simple recognition of the limits of all systems. One can attempt, within the context of gravity, the body, the incoming force, etc, to achieve "total non-resistance," but there is a point beyond which "maximal non-resistance" becomes "resistance."
Now -- and this is a key point -- it may be that the maximal non-resistance amounting to resistance can only be approached by a psychological orientation toward "totality." This is a form of "total non-resistance" which renders the statement entirely sensible and isn't susceptible to the same issues of reification.
Apologies for the formatting.
Fred Little
View Public Profile
Visit Fred Little's homepage
Find More Posts by Fred Little


text:
Human trafficking on national, regional forefront
In just the course of the past few weeks, the arrests of two Acadiana women as well as the FBI's Operation Cross Country arrests, which resulted in the arrests of 159 "pimps" and the recovery of 105 children nationwide, have brought the issue of human trafficking to the attention of area residents. In Lousiana, the FBI's raid resulted in the arrests of 76 people on sex trafficking related charges and the recovery of six children. One of the people who was arrested, Rita May Trahan, 26, is from Elton.
"Child prostitution remains a persistent threat to children across America," said Ron Hosko, assistant director of the FBI's Criminal Investigative Division. "This operation serves as a reminder that these abhorrent crimes can happen anywhere, and the FBI remains committed to stopping this cycle of victimization and holding the criminals who profit from this exploitation accountable."
While the "criminals who profit" comprised the majority of those arrested on Monday, it was a staggering number of children, the youngest being 9 years old, that were rescued troubling those who watched the news on Monday.
According to the FBI statement, most of these children were either runaways or foster children.
"Most of these children didn't have people who were actively seeking them," said Hosko during his press conference.
The most vulnerable of the children who find themselves trapped in the sex trade are from the 13- to 16-year-old age range. The people they will eventually succumb to will approach them and ask them if they "are looking to make some money." Eventually, they find themselves "numbed" to their situation and find themselves completely dependent on their pimps, who often use drugs, physical and torture to control their victims.
One girl freed in an earlier operation, identified only as Alex in an interview posted on the FBI's website, was 15 when she left a difficult home situation, and 16 when she turned to prostitution.
"At first it was terrifying, and then you just kind of become numb to it," she said of her experience on the streets. "You put on a whole different attitude - like a different person. It wasn't me. I know that. Nothing about it was me."
Major Keith Latiola, with the Acadia Parish Sheriff's Office, said that Acadia Parish hasn't had any problems with any residents being involved in any human trafficking operations. He did have a booklet from the FBI, which was sent to law enforcement officials around the country, which detailed the problem.
"Worldwide, it's estimated that $37 billion a year is spent on the illegal sex trade," said Latiola. "Most of the people that fall victim to it are poor and uneducated. These guys will promise them the world and take them to places like the United States or Western Europe that are much more affluent and there is more money to be made."
According to Acadia Parish resident Richard Newman, however, it is possible that people who deal in human trafficking may be those you would never suspect. Newman was part of a group that went to New Orleans ahead of this past year's Super Bowl to rescue youths who are caught up in the sex trade. Sadly, many large sporting events that draw thousands of people to an area have also become a money-maker for those in the sex trade. Newman was asked if anything about his trip caught him completely by surprise.
"I was amazed at how much of this takes place completely out in the open and we don't even know about it," he said. "It could literally be your neighbors in Crowley or Eunice...everyday people, and we would never suspect it."
Newman was also asked about the website "Backpage," which led to the arrest of many of those who were picked up this past weekend. The site, which has many legitimate business offers, has a heading called escorts which takes people to a list of people in the area that provide sexual services. It is on this site that many underage victims of child trafficking were located.
"I wasn't involved in that aspect of our operation but we had people that looked into [computer solicitation]," he said. "They said that there are certain keywords in these ads that let pedophiles know that these people are underage."
Newman said that he was impressed with the scope of the FBI's raid.
"I thought it was great how far-reaching their operation went," he said. "What they are doing is just breaking down the network and finding out how extensive it is."
Not all people arrested for human trafficking are part of some worldwide criminal network. As was evidenced by the arrest of two Lafayette area women, Lorrie Anderson and Katherine Vidrine, these people can simply be those who use a young child for personal monetary gain or by crossing a local, parish or state border with a child for sexual purposes.
Lorrie Anderson was arrested at her Lafayette home on July 24. She is also charged with human trafficking, aggravated incest and aggravated rape. State Police detectives received a complaint about that she allegedly had sex with more than one child relative. Troopers say their investigation uncovered that Anderson brought the child to a location in Lafayette Parish to have sex for money on more than one occasion.
Katherine Vidrine allegedly profited by bringing a juvenile to several homes for sexual encounters with men. The juvenile, who was under the age of 12, was molested by several men including, allegedly, a 52-year-old man who was charged with molestation of a juvenile, indecent behavior with a juvenile, pornography involving juveniles and possession of marijuana. The juvenile claimed that Vidrine was present during some of her encounters.
Trooper Steven Hammons with the State Police gave an interview after Vidrine's arrest.
"The one good thing out of this case is that the child is safe now," he said. "The child will no longer be victimized. That's such a terrible crime. This is the one thing that you can look at and say, at least we were able to rescue you,"


text:
European stocks fall in early trade
By IRIS
Published: 21st July 2014 02:19 PM
Last Updated: 21st July 2014 02:19 PM
European stock markets are trading lower on Monday. Europe's leading Blue-chip index, EURO STOXX 50 declined 12.80 points or 0.41 percent to trade at 3,145.02.While UK's benchmark index FTSE 100 fell 39.90 points or 0.59 percent to trade at 6,698.42.Germany's benchmark index DAX lost 72.54 points or 0.74 percent to trade at 9,681.34.Meanwhile, French benchmark index CAC 40 declined 16.83 points or 0.39 percent to trade at 4,299.29.
Disclaimer: We respect your thoughts and views! But we need to be judicious while moderating your comments. All the comments will be moderated by the NIE editorial. Abstain from posting comments that are obscene, defamatory or inflammatory, and do not indulge in personal attacks. Try to avoid outside hyperlinks inside the comment. Help us delete comments that do not follow these guidelines.


text:
Other projects made by Sugar n Spice:
Offer some kudos...
Join the conversation...
Ask a question...
Add your comment...
|Here are some details about my project:
|Home Decor
|Traditional, Whimsical, Classic, Funky, Casual
What was your source for this quilting project?
Online Photo or Website
Name of website or photo Collecte Des Oefs
What are you most proud of? Loretta is so happy with it! She is a quilter and the one who has encouraged me to jump into quilting with both feet! I have...and LOVE IT!
What advice would you give someone starting this project? Watch for the direction of the French language print as you cut the various pieces for the blocks. You may want to make simple templates of the pieces that use it and make directional arrows on them, prior to cutting, if that is level of detail you want.
I absolutely love this quilt as I too love roosters. I'm a city girl but I love cows, roosters and all things country. Great job!
Thank you! I enjoy all things country too! There is a French twist to it, I like! I want to make one for myself. What is your latest project?
Well Loretta is very lucky to have received such a beautiful quilt with beautiful fabric! I wonder if this fabric is still available? As for me I am working on the craftsy BOM project as well as a baby quilt for a dear friend of mine who is having her first grandson in August. Of course I have a million other projects I would like to start or finish in between but I am sure you know how that goes. Thanks for sharing such an inspiring quilt!
Thank you beeboop71! I haven't checked on the fabric availability, but I hope it is still out there. I would love to make one for our home. I can't wait to see your Craftsy BOM and the baby quilt. What a great friend you are for being so generous! You are correct. I also am in the long line of 'I would love to make that one, oh wait, look at that one, I MUST have that' project agenda! HA~ We love it~
where can I get the material??
Hi Frances! If you click on the link of the pattern, Collecte Des Oefs, there is a link under the pattern to view fabrics. They are from Whistler Studios and are archived fabrics.
Hi Frances! If you click on the link of the pattern, Collecte Des Oefs, there is a link under the pattern to view fabrics. They are from Whistler Studios and are archived fabrics.


text:
Take your itinerary with you using our My Alaska Trip feature and the TravelAlaska app.
My Alaska Trip に追加
102 Denali
Coffman Cove,
Visit Website
Mile 48.7 Sterling Hwy
Cooper Landing ,
404 First St.
.5 Healy Spur Road
100 Marine Way, Suite 200
101 Dunkel St
122 Second Ave.
201 Sterling Highway
Homer ,
131 Front Street
7744 E. Visitors View Ct.
737 Salmon Way
19 Fram St
#7 6488 Klawock-Hollis Hwy
2001 Seward Highwy
Broadway between 2nd & 3rd Avenues
44790 Sterling Hwy
35571 Kenai Spur Hwy.
corner of Alaska Hwy and Center Street
100 Hanson Street
800 Glacier Avenue
5 Broadway
Alaska (AK)
309 Fairbanks Drive
524 West Fourth Avenue
296 Campbell Drive
Sort by region:
Best-selling travel guide for attractions, restaurants, accommodations, gas stations, fishing & camping along Alaska, Alberta, British Columbia, NWT & Yukon highways. 752 pages; mile-by-mile logs of more than 60 highways; 612 photos; 100-plus maps; and suggested itineraries. E-book & app available. The bible of north country travel.
The Mat-Su Valley Visitor Center, located at Mile 35.5 Parks Hwy. (just north of Anchorage), is your one-stop shop to learn about the Mat-Su Valley. Take a trip on the Glenn Highway National Scenic Byway north to Matanuska Glacier and the Sheep Mountain area for breathtaking views. Or travel north on the Parks Hwy. to Talkeetna, the gateway to Denali. Flightseeing, jet boating and rafting are a few of the popular activities. Along the way, stop at the Palmer Musk Ox Farm, Hatcher Pass and Independence Mine or the Iditarod headquarters in Wasilla. Visit the towns of Palmer, Wasilla, Big Lake, Willow and Talkeetna in this region, which encompasses 23,000 square miles. Keep an eye out for wildlife, including moose, bears and migratory birds. The Mat-Su Valley is where Alaska comes to play!
Discover what Alaskans already know: Just south of Anchorage and easily accessible by land, air or sea, nothing about the Kenai Peninsula is formal or stuffy. No other destination offers such an up close and personal Alaskan experience. That's why we are known as Alaska's Playground. Order a free guide. firstname.lastname@example.com.
Find accessible glaciers, 1,500 resident moose, views of Denai and 300 miles of wilderness trails all in one place. At the heart of air, road and rail travel in Alaska, Anchorage has phenomenal access to national parks and countless outdoor adventures. The city blends the best of these natural wonders with urban amenities including tax-free shopping, a wide range of accommodations and a surprising culinary diversity.
"At the End of the Road... The Adventure Begins" on stunning Kachemak Bay! Enjoy breathtaking panorama views of the Kenai Mountains, volcanoes and glaciers. A home base for great fishing, kayaking, bear-viewing, hiking, foodie and art vacations. We're also known as the eco/adventure destination of Alaska. Homer is a year-round destination, come and explore!
Alaska's Hidden Treasure-summer festivals to winter skiing, we have it all for your dream vacation.
We provide visitor info in the Mat-Su Valley and operate a visitor center at Mile 35.5 Parks Hwy.
A charming little town that features the beautiful turquoise waters of Kenai Lake & the Kenai River.
Cordova is an authentic commercial fishing town not built for tourists and that is precisely why you should come for a visit. You will not find all the typical tourist trappings. What you will find is a town immersed the the culture of the outdoors. Commercial fishing is the life blood of this town with nearly every family benefitting from employment directly in the fishing industry or a business that supports the fishing industry. The world famous Copper River Salmon are caught here by the intrepid men and women that brave the cold waters of the Copper River, the Gulf of Alaska and Prince William Sound.You are cordially invited to hike the miles of USFS trails along with the local residents who travel these trails as if they were the city sidewalks in your home town. Welcome!
Visit Seward and see why Alaska starts here! Free information on activities and accommodations, including Kenai Fjords National Park, Exit Glacier, wildlife/glacier viewing, fishing, hiking, kayaking, Seward Silver Salmon Derby & Mount Marathon footrace. firstname.lastname@example.com.
WELCOME TO SOLDOTNA, ALASKA! Home to the world's largest King salmon and where the famous Kenai River flows! Join us in Soldotna for world class fishing and fabulous accommodations. With Soldotna as your home base while visiting Alaska's Kenai Peninsula, you'll enjoy the best Alaska has to offer right at your doorstep. The list of activities you will enjoy during your trip are endless! Wildlife viewing, flightseeing, flyout fishing and bear viewing, bird watching, horseback riding, canoe and hiking trips, winter recreation, shopping, gourmet dining and more await you in Soldotna, Alaska! Stop by the Visitor Center for information on the area, view a variety of animal exhibits, including the world record King salmon, or take a walk along the elevated boardwalk. Video: https://vimeo.com/14917669
View the world-record King Salmon or pick up info & maps at the Soldotna Visitor Center.
Everything you came to see & do in Alaska all in the one place. Mountains, glaciers, wildlife, fishing, history, tours, adventure. More adventure awaits when the snow falls - heli-skiing, snowboarding, snow mobiling & more. Come see the unparalleled natural beauty that entices people from around the world to visit. Even Mother Nature has favorites! Come see why, Visit Valdez! Alaska's year-round playground. Order your Free Vacation Guide Now! Email: email@example.com.
Unique, seaside community in a spectacular setting. Gateway to your Prince William Sound adventure.
Come explore! Unalaska holds many surprises and rare opportunities for the adventure traveler, WWII history enthusiast, birder or fisherman. Enjoy our cultural museum, WWII Center, Deadliest Catch crab boats, hiking, kayaking and gorgeous scenery. Explore WWII bunkers, savor a 360-degree panoramic view from 1,600 ft. and marvel at the beauty in the Heart of the Aleutians. Contact us for a free visitor guide. firstname.lastname@example.com..
Experience Alaska untamed when you go beyond the end of the road. Kodiak is the only place you can see the legendary Kodiak brown bear. Fishing, hiking, biking, kayaking, sightseeing, whale watching, bird watching & photography await you on Kodiak Island. If you are looking for an authentic Alaskan experience, visit Kodiak. Call for a free visitors guide.
Come explore! Unalaska holds many surprises and rare opportunities for the adventure traveler, WWII history enthusiast, birder or fisherman. Enjoy our cultural museum, WWII Center, Deadliest Catch crab boats, hiking, kayaking and gorgeous scenery. Explore WWII bunkers, savor a 360-degree panoramic view from 1,600 ft. and marvel at the beauty in the Heart of the Aleutians. Contact us for a free visitor guide. firstname.lastname@example.com.
A place exists in Alaska where the past lives on, where the cries of "gold in the Yukon" still echo from steep canyon walls, where the sounds of barroom pianos and boomtown crowds ring out in the night. A place where the romance and excitement of yesteryear linger around every street corner, every bend in the trail. That place is Skagway, come join us! firstname.lastname@example.com.
Juneau offers Alaska's top experiences: Glacier Bay National Park, Tracy Arm Fjord, Tongass National Forest, Mendenhall Glacier/Juneau Ice Field, whales, hiking, kayaking and sportfishing. Enjoy our historic Victorian downtown and gold rush past. Visit us via Alaska Airlines, Delta Airlines, ferry or cruise. Order your free travel guide at 877-581-2201. Follow us on Facebook: www.facebook.com/TravelJuneau.
Prince of Wales Island is surrounded by Tongass National Forest, State & Native lands. USFS maintains many trails, boardwalks & promenades with more opening each year. Scenic Byways are traversed by cyclists, RVs, hunters, nature & bird-lovers alike. Phone for your copy of our annually-produced Visitor Information. Klawock, Alaska. firstname.lastname@example.com.
Gateway to Glacier Bay National Park: Gustavus is not too big or too small - it's just right!
Unspoiled and unhurried, Haines is the natural choice! We are renowned for our stunning scenery, abundant wildlife and rich culture. Make Haines your home base for excursions into the Golden Circle, Glacier Bay, Interior Alaska and the Yukon. Easy connections by air, sea and highway. For free vacation planner call Toll Free or visit our website.
Juneau offers Alaska's top experiences: Glacier Bay National Park, Tracy Arm Fjord, Tongass National Forest, Mendenhall Glacier/Juneau Ice Field, whales, hiking, kayaking and sportfishing. Enjoy our historic downtown & gold rush past. Visit us via Alaska or Delta Airlines, ferry or cruise. Order a free travel guide at traveljuneau.com. Follow Travel Juneau on Facebook.
Make Ketchikan your home for adventure! Our scenic coastal town is bustling with world-class fishing, hiking and culture. Only a 90-minute flight from Seattle delivers you to the heart of the Inside Passage and a truly unique destination rich with history. Before arriving, connect with our friendly and knowledgeable location experts to make the most of your escape. firstname.lastname@example.com.
Tired of the ususal? Then come to Pelican! firstname.lastname@example.com.
Petersburg is a small, vibrant commercial fishing town in the heart of the Tongass National Forest. It's a special place to enjoy unbounded natural beauty. If you love the outdoors and exploring, this is the place for you!!Watch pods of humpback whales feeding, take a leisurely walk or a mountain hike, or go sport fishing for salmon and halibut. You can even kayak or take a float plane tour. While wandering the docks, stop to talk to local fisherman and get to know some real Alaskans. Our stores are locally owned & open year round. Quaint cafes, a new library with free WiFi, and full local services offer something for everyone. Petersburg's great scenery, recreation opportunities and charming local character make it the perfect vacation destination for families of all ages.
Little Norway-Big Adventure! Travel, relocation, business info. firstname.lastname@example.com.
Join us for our Arts Festival, Halibut Derby & Salmon Tournament. Experience our scenery, wildlife, kayaking, canoeing, hiking, biking, nearby caves, fishing, hunting, beachcombing, bird watching & more. We offer many services-lodging with or without meals, library with internet, fuel, bar/liquor store, general store, misc. rentals, fishing charters, etc.
If you are looking for an unforgettable experience, extraordinary wildlife viewing, exciting outdoor adventure, fantastic fishing, awesome pristine scenic views, colorful history and Tlingit Native culture and arts then come to Wrangell in southeast Alaska – we offer something for everyone!Stikine River Delta hosts thousands of birds in Spring and Fall during annual migration. Anan Wildlife Observatory is a haven for brown and black bears as well as eagles, salmon, seals and sealions. Hike trails through muskegs and old growth forests, search for mysterious petroglyphs, fish for the big one, visit our award winning museum or even play a round of golf at the USGA Muskeg Meadows – these are all just some of the fun things to do in Wrangell! Stop by the Visitor Center!
Be inspired by the light of the Aurora Borealis. Renew your energy under the Midnight Sun. Experience the warmth of Fairbanks—Alaska's Golden Heart—and the gateway to Denali, Alaska's Interior and Arctic. Call 1-800-327-5774 or go online to request your free Fairbanks Visitors Guide.
Be inspired by the light of the Aurora Borealis. Renew your energy under the Midnight Sun. Experience the warmth of Fairbanks—Alaska's Golden Heart—and the gateway to Denali, Alaska's Interior and Arctic. Call or go online to request your free Fairbanks Visitors Guide.
Representing Denali Borough, the premier Alaska destination. email@example.com.
Information junction! If you aren't in Tok, you're missing the boat!
The Yukon is one of the most beautiful and exciting locations in the world. Featuring breathtaking scenery, unique culture and a host of incredible activities, the Yukon is the ideal place to learn, explore and relax. With the help of our Trip Planning section, you can find the accommodations, attractions and activities that best suit your interests and desires. Whether you want to shoot the rapids on a whitewater raft, journey through the incredible Yukon landscape in your RV or relax in a quaint bed and breakfast, the Yukon is sure to satisfy.Plan your trip today for a truly larger than life experience!
Guys and Gals: 5% Off Normal Package Price Listed Below for May, June, August, September


text:
RAWR Dinosaur Blank Cards - Printable Stationery by Paperholic - Thank you Greeting Card
Product Info
Leave a personal message using our printable blank cards decorated with fun little dinosaurs. Available in 4 different dinosaurs - T-rex, brontosaurus, stegosaurus, & triceratops. Print as much as you want as they can be used for any occasions!
Our listing is a high resolution non-editable PDF file. Listing will be EMAILED to your Etsy related email address. NO actual items will be shipped.
✦ 3"x4" blank message cards in 4 styles
✦ envelope
✦ stickers/clip art (1 page)
> Adobe Reader® (most recent )
> Printer
> 8.5"x11" Card stock, sticker paper
> Scissor or utility knife
> Envelope
** This is an INSTANT DOWNLOAD. Once payment has been secured, Etsy will provide a link where you may download your file.**
Please keep in mind, Paperholic's PDF files are for PERSONAL use ONLY. Commercial use is strictly prohibited – that means no redistribution/sharing of any type, resale and/or alternations of the original file and/or prints.
Actual prints may appear different on paper when comparing to the monitor, paper settings, ink and paper brands.
By purchasing Paperholic files, you are hereby agreeing to the terms of use.
© Paperholic. All rights reserved. For personal use only, not commercial use. Copyright is NON-transferrable.


text:
A slang term for receiving oral sex.
"You know that girl Kristen? Yeah, last summer we played mahjongg."
by Chinese Checkers July 10, 2008
Trending Now
Can you define these popular missing words?
Top Definition
A band with its roots in Columbia, Missouri, that, for some strange reason, has not been discovered/devoured by the world as a whole. Producing a mix of rock & roll, electronica and incredible, Mahjongg will make your head explode...in a good way.
Mahjongg is the greatest band that no appreciates fully.
by No, seriously... March 18, 2005


text:
Lenovo Z580 59345242 Notebook PC - 3rd Gen. Intel Core i7-3520M 2.9GHz, 4GB DDR3, 500GB HDD, DVDRW, 15.6" Display, Windows 8 64-bit (Refurbished)Item#: T71-156409 RF | Model#: 59345242 |
Currently Out Of Stock!
You May Consider This Alternative
Lenovo Z580 Core i7 500GB HDD 4GB DDR3 Note REFURB Product Details
Lenovo 59345242 Z580 Notebook PC
Accomplish more calculations and processing using the Lenovo 59345242 Z580 Notebook PC. This notebook PC features the cutting-edge 3rd Gen Intel Core i7 3520M 2.9GHz Dual-Core processor that delivers exceptional processing capacity so you can expect outstanding performance from your applications. The Lenovo 59345242 Z580 Notebook PC's 4GB RAM enables your system to withstand memory-demanding activities, allowing you to perform tasks simultaneously without slowing your PC. With its 500GB hard drive, you can now save tons of downloads, multimedia files, documents, and various digital data. It's designed with a 15.6" display to make sure that you can view your files, applications, and games as clear as possible. And on top of that, the new Windows 8 is installed to this PC to give a million more possibilities to your computing. Grab the Lenovo 59345242 Z580 Notebook PC right away!
What It Is Why You Need It:
- 3rd Gen Intel Core i7 3520M 2.9GHz Dual-Core processor; grants superb computing performance
- 4GB RAM; enhances system speed and responsiveness
- 500GB HDD; offers plenty of space to accommodate your most important files
- 15.6" Display; guarantees stunning visual quality
- Windows 8; lets you enjoy new and fun features
Refurbished products are products that were originally purchased and returned by customers like yourself. The term refurbished is used to describe products that were returned to their manufacturers specification then tested and repackaged for sale. We utilize a third party of professional technicians who first troubleshoot and then perform any repairs that are necessary to restore the product to like new condition. Refurbished products represent a great value and we offer them with confidence knowing that every refurbished product was tested by a trained group of professionals. Refurbished products are warranted for up to 90 days after purchase. Any product failure not originating from defects in materials or workmanship will not be considered covered under warranty. Warranty terms applicable to refurbished products may vary; see below for specific warranty information and consider purchasing an extended service plan if you desire even more coverage.
Manufactured by: Lenovo
Warranty provided by: Lenovo
UPC No:
Mfg Part No: 59345242
Box Size:
( Length:20, Width:12, Depth:3)
Shipping Weight: 7.6500 pound(s)
Click here for full warranty and support information
- Lenovo logos are registered trademarks of Lenovo. All others trademarks and copyrights mentioned herein are the property of their respective owners.


text:
Movie Power Rankings: 'Inception' uses 3 1/2 minutes to hit No. 1
Who knew only 3 1/2 minutes could generate so much excitement? The always secretive Christopher Nolan did, that's who. The "Dark Knight" mastermind showed a clip from his new Leonardo DiCaprio thriller "Inception" at San Francisco's WonderCon this past weekend and people were still talking about it the following day.
Not much is still known about Nolan's latest endeavor, except that it appears to deal with covert espionage within character's dreams. Could it be "The Matrix Revolutions" without the leather jackets? If you take that as a compliment to the Wachowskis , then yes. Moreover, the visually impressive film is slowly positioning itself for a potential awards season run later this year. There's still a long way to go until the film debuts on July 16, but this weekend's reveal was more than enough to push "Inception" to the top spot in the power rankings. As for the rest of the most 15 buzzed about films in Hollywood? Read 'em and weep.
Posted: Tuesday, April 6, 2010.
1. "Inception" (new)
Director Christopher Nolan shows up unannounced at WonderCon and wows the crowd with a 3 minute clip from his new dramatic thriller. Can you say potential Best Picture contender? Yep, it's only April and we went there. Deal with it.
2. Will Smith (last week no. 4)
Boy, those "Independence Day" sequel rumors are getting stronger every day. Who knew Big Willie would go old school for his next project? Or will he?
3. "Clash of the Titans" (last week no. 6)
$61 million is nothing to scoff at. And, the blogosphere's overreaction to the 3-D conversion was embarrassing. It was nowhere near as weak as "Alice in Wonderland."
4. "The First Avenger: Captain America" (last week no. 3)
Chris Evans teases the WonderCon audience about his new role, tells HitFix he's not sure if he'll go blond or not and gets a sidekick in "Gossip Girl's" Sebastian Stan.
5. Netflix (new)
Steve Jobs and the iPad just saved Netflix from fading into history like Hollywood Video and the quickly evaporating Blockbuster.
6. "Why Did I Get Married Too" (new)
Tyler Perry's sequel to the universally ignored (by the media at least) "Why Did I Get Married?" was just as overlooked this time around, but opened to almost $8 million more on its opening weekend than its predecessor. And it's not even in 3-D!
7. "Kick-Ass" (last week no. 8)
We'd like to say we weren't influenced by the fact that HitFix's own Drew McWeeny moderated a spectacularly successful panel for the film at WonderCon, but more importantly, there is a growing legion of press who never read the comic who adore the picture. How big can it open?
8. "Tron Legacy" (new)
Encom makes an announcement in downtown San Francisco, a skydiver has a safe landing and the buzz plays better online than in person. Guess which matters most?
9. "A Nightmare on Elm Street" (new)
Internet gold? "Twilight." Internet silver? "A Nightmare on Elm Street."
10. "Twilight Saga" (last week no. 2)
Stephenie Meyer announces a new book (can you say eventual movie?) and new stills hit the net. Any other franchise? Big week. "Twilight"? That's how the vampires roll.
11. "How To Train Your Dragon" (last week no. 10)
Even with "Clash" coming into the marketplace, "Dragon" only dropped 33%. That's a great sign of amazing word of mouth. Plus, no family competition until, um, "Furry Vengeance" on April 30.
12. MGM (new)
Tick tok, tick tok, tick tok. Anyone want to place bets on which studio produces and releases the next James Bond film? It probably won't be MGM...
13. "A Very Harold and Kumar Christmas" (new)
The health care battle must have really taken a toll on Kal Penn. He's left his position at the White House to reunite with John Cho for a third installment of everyone's favorite 21st Century stoner duo.
14. Sandra Bullock (same as last week)
If Bullock's soon to be ex-husband has any more mistresses come out of the woodwork, the Best Actress Oscar winner may never leave her Hollywood Hills home.
15. "XXX 3" (new)
Paramount Pictures brings the "XXX" franchise with Vin Diesel and Rob "Even Joel Schumacher thinks I'm a hack" Cohen back to life after Sony Pictures passes. We get that every studio needs reliable franchises, but you let the rights to "Tomb Raider" go for this?
Dropping like a rock...
MGM's financial troubles and underwhelming auction process are making bidding for this now available brand and library almost impossible. Will Disney have to take it off the block?
*"Knight and Day"
We hear it might be pretty good, but Fox please spare us a SportsCenter sponsorship all the way through June.
*"The Runaways"
We don't mean to harp on the biopic as its got style and Stewart is pretty great in it, but is Apparition really still planning on going wide with this one? Really?
Previous Rankings:
Tues. March 30, 2010
What do you think of this week's rankings? Share your thoughts below.
For all the latest inside analysis and tidbits from the world of entertainment, follow Gregory Ellwood on Twitter @HitFixGregory.