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NSCLC is "Major Battlefield" as Merck,...
Expanding Use of NGS Has Largely...
Wall Street Decline Takes Its Toll...
LC-MS Gains Favor Due To the...
When PerkinElmer acquired Caliper Life Sciences in November 2011, it obtained not only Caliper's signature microfluidics and lab-on-a-chip technologies, but also the expertise that Caliper gained through its prior acquisitions of several companies over 10 years.
Caliper already had a suite of products for DNA, RNA, and protein testing, tissue analysis, and imaging technologies for small animals. "But Caliper did not have reagents or cellular assays. We relied on other companies to provide them," says Kevin Hrusovsky, formerly CEO of Caliper and now senior vp and president of PerkinElmer Life Sciences & Technology.
What Caliper lacked it gained from PerkinElmer, whose acquisitions of companies like New England Nuclear and Evotech Technologies provide a large portfolio of reagents and cellular capabilities. "Caliper capped off our 2011 acquisitions. It gives us a complete spectrum of products from molecular testing to cellular and tissue testing to preclinical animal imaging," says Daniel Marshak, Ph.D., senior vp and CSO of PerkinElmer.
The combined technology platforms of Caliper and PerkinElmer expand offerings for molecular, cellular, animal, and tissue imaging. These tools improve sample preparation and workflows in next-generation DNA sequencing, the detection of environmental contaminants and food pathogens, and quality control and quality assurance of biotherapeutics and biologics, according to Dr. Marshak.
Hrusovsky leads the PerkinElmer Life & Technology business, which integrates the former Caliper organization with PerkinElmer's research business. For at least the first year, the Caliper name will be retained "because there's a lot of brand loyalty for Caliper products," says Hrusovsky. The headquarters of the PerkinElmer Life Sciences & Technology business is located in Hopkinton, MA, where Caliper was based.
Caliper has been involved in microfluidic lab-on-a-chip technology since 1998. Microfluidics continues to be important and is the fastest-growing technology portfolio at PerkinElmer. "The growth in microfluidics has been staggering," says Hrusovsky.
Many problems that plagued microfluidics in the early days have been solved. The original microfluidic instruments were as large as a dining room table, cost $1 million, and the chips processed in them were the size of a quarter. Caliper invested $300 million in R&D to improve the systems. "The platform today looks like a toaster and works much better," says Hrusovsky.
Microfluidics is the underlying technology behind next-generation sequencing as well as many biotherapeutics on the market today. For example, microfluidic-based tests are the quality assurance gold standard, sanctioned by the FDA, for some biotherapeutics on the market.
Microfluidics also fits with the trend toward increasingly smaller sample sizes. "Medicine is trying to test significantly more biomarkers on smaller and smaller samples," says Hrusovsky. For example, rather than doing expensive and invasive biopsies, physicians may perform needlepoint aspirates of much smaller size. "Our technologies enable researchers and clinicians to do more testing faster and with less sample," says Hrusovsky. Tests also can be multiplexed for simultaneous analysis.
Although microfluidics is more than a decade old, "it has moved with the times and now supports high-throughput screening," says Dr. Marshak. Biochemical and cellular assays, which once performed one sample at a time, have been automated for high-content screening in biopharmaceutical research.
Advancing personalized medicine was a major goal at both Caliper and PerkinElmer, Dr. Marshak reports, noting that the experts at PerkinElmer remain dedicated to providing life scientists with drug discovery tools for genetic, biochemical, and cellular research.
PerkinElmer offers tools and services for clinical and preclinical imaging, digital pathology, sample preparation for next-generation sequencing, molecular and companion diagnostics, stem cell research, and the development of biotherapeutics and vaccines.
These technologies are intended to progress personalized medicine by improving patient diagnosis, prognosis, and treatment. Novel technologies in areas like genomic analysis, biomarkers, and imaging will help detect diseases earlier and select individualized treatments that best benefit patients.
PerkinElmer already has experience in some areas of personalized medicine, particularly prenatal screening and testing newborns for genetic inborn errors of metabolism. In Asia, PerkinElmer systems are widely used to identify the cause of infectious diseases, says Dr. Marshak.
A new frontier is unraveling to examine how environmental factors, genetic predisposition, and lifestyle choices interact to affect cancer, heart disease, and other illnesses. "We're evolving from personalized medicine to personalized health," says Hrusovsky, noting that three cornerstones of personalized health are detection, treatment, and prevention.
"The prevention aspect needs more understanding of the environmental causes of disease," Hrusovsky says. For example, it's projected that 80% of breast cancers are caused by environmental, or epigenetic, factors. Similar to PerkinElmer's technology that screens newborns for inborn errors of metabolism, healthcare in the future will consist of more screening options to catch diseases like cancer long before symptoms occur. By the time a tumor is palpable, it has a high potential to be metastatic.
"We have all the tools to process a person's epigenome to pursue and integrate the way medicine and healthcare will be practiced in the future," says Hrusovsky.
PerkinElmer recently expanded its Epigenetic Biochemical Toolbox to cover 35 validated enzymatic assays to detect post-translational modifications of histone H3 and p53.
To round out its capabilities, PerkinElmer's latest acquisitions also include informatics companies. "We're integrating informatics into all of our platforms to manage data. Then we'll transcribe the information to help doctors apply it to patients," says Hrusovsky.
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text:
Ringworm Center - Bellingham, WA
- WebMD Physician Directory of Bellingham Dermatologist Doctors
- Related Ringworm Articles
- Bellingham Emergency Contacts
- Nearby Bellingham Hospitals
- Find a Local Pharmacy on RxList - Bellingham
Bellingham Dermatologist Doctors for Ringworm
Type of Physician: Dermatologist
What is a Dermatologist? A certification by the Board of Dermatology; practitioners treat pediatric and adult patients with disorders of the skin, mouth, hair and nails as well as a number of sexually transmitted diseases. They also have expertise in the care of normal skin, the prevention of skin diseases and cancers, and in the management of cosmetic disorders of the skin such as hair loss and scars.
Specialty: Dermatology
Common Name: Skin Doctor
Dermatologist Doctors in Bellingham * results
- 2
Kirstin R. Curtis
Mt Shuksan Family Medicine
2101 Cornwall Ave Ste 101
Bellingham, WA 98225
(360) 647-1900
- 1 office location(s)
- 3
Julianne H. Snell
Bellingham Dermatology Clinic
2075 Barkley Blvd Ste 225
Bellingham, WA 98226
(360) 647-2188
- 1 office location(s)
- 4
Bruce A. Bowden
Bruce A Bowden MD
2075 Barkley Blvd Ste 220
Bellingham, WA 98226
(360) 647-0220
- 1 office location(s)
- 5
Elizabeth M. Vennos
Bellingham Dermatology Clinic
2075 Barkley Blvd Ste 225
Bellingham, WA 98226
(360) 647-2188
- 1 office location(s)
- 6
Jan P. Dank
Dermatology & Laser Center Northwest
905 Squalicum Way Ste 101
Bellingham, WA 98225
(360) 676-1470
- 1 office location(s)
- 7
Stanley C. Gilbert
Dermatology & Laser Center Northwest
905 Squalicum Way Ste 101
Bellingham, WA 98225
(360) 676-1470
- 1 office location(s)
- 8
Laurie Jacobson
Pacific Dermatology & Cosmetic Center
11011 Meridian Ave N Ste 102
Seattle, WA 98133
(206) 859-5777
- 2 office location(s)
- 9
Amy S. Gouley
Rosario Skin Clinic
3110 Commercial Ave Ste 105
Anacortes, WA 98221
(360) 588-0613
- 1 office location(s)
- 10
Randy G. Banks
Rosario Skin Clinic
1600 Continental Pl Ste 101
Mount Vernon, WA 98273
(360) 336-3026
- 2 office location(s)
- 11
Casondra A. Webb-Soto
Rosario Skin Clinic
3110 Commercial Ave Ste 105
Anacortes, WA 98221
(360) 588-0613
- 1 office location(s)
- 12
Amber D. Fowler
Rosario Skin Clinic
1600 Continental Pl Ste 101
Mount Vernon, WA 98273
(360) 336-3026
- 3 office location(s)
Don't see your city? Use the WebMD Physician Directory to expand your search.
Ringworm facts
- Ringworm is a common fungal infection of the skin and is not due to a worm.
- The medical term for ringworm is tinea. The condition is further named for the site of the body where the infection occ...
Other Related Ringworm Articles
Emergency Contact for Bellingham
- In case of Emergency, call 911
Nearby Bellingham Hospitals results
- 1St Joseph Hospital South
2901 Squalicum Pkwy
Bellingham, Washington 98225
(360) 734-540
- 2St Joseph Medical Center
2901 Squalicum Pkwy
Bellingham, Washington 98225
(360) 734-540
- 3Island Hospital
1211 24th St
Bellingham, Washington 98221
(360) 299-130
- 4United General Hospital
2000 Hospital Dr
Bellingham, Washington 98284
(360) 856-602
- 5Skagit Valley Hospital
1415 E Kincaid St
Bellingham, Washington 98274
(360) 424-411
- 6Naval Hospital
3475 N Saratoga St
Bellingham, Washington 98278
(360) 257-997
* Provider Directory Terms of Use:
The WebMD 'Provider Directory' is provided by WebMD for use by the general public as a quick reference of information about Providers. The Provider Directory is not intended as a tool for verifying the credentials, qualifications, or abilities of any Provider contained therein. Inclusion in the Provider Directory does not imply recommendation or endorsement nor does omission in the Provider Directory imply WebMD disapproval.
You are prohibited from using, downloading, republishing, selling, duplicating, or "scraping" for commercial or any other purpose whatsoever, the Provider Directory or any of the data listings or other information contained therein, in whole or in part, in any medium whatsoever.
The Provider Directory is provided on an "AS-IS" basis. WebMD disclaims all warranties, either express or implied, including but not limited to the implied warranties of merchantability and fitness for particular purpose. Without limiting the foregoing, WebMD does not warrant or represent that the Provider Directory or any part thereof is accurate or complete. You assume full responsibility for the communications with any Provider you contact through the Provider Directory. WebMD shall in no event be liable to you or to anyone for any decision made or action taken by you in the reliance on information provided in the Provider Directory.
The use of WebMD Provider Directory by any entity or individual to verify the credentials of Providers is prohibited. The database of Provider information which drives WebMD Provider Directory does not contain sufficient information with which to verify Provider credentials under the standards of the Joint Commission on Accreditation of Healthcare Organizations (JCAHO), National Committee for Quality Assurance (NCQA) of the Utilization Review Accreditation Committee (URAC).
By using the WebMD Provider Directory, you agree to these Terms and Conditions.

subset: commoncrawl


text:
Attendance Policy
Policies and Procedures for Disability-Related
Disability Services (DS) does not have a role in determining course attendance policies. Because attendance may be integral to the pedagogic process, these policies are set by faculty at the college, departmental, or individual level. In some cases, attendance is fundamental to course objectives; for example, students may be required to interact with others in the class, to demonstrate the ability to think and argue critically, to participate in group projects.
Similarly, instructors also determine policies regarding make-up work and missed quizzes and exams. Faculty members are not required to lower or effect substantial modifications to essential requirements/academic standards for accommodation purposes.
DS can provide students with written verification (Request for Accommodations) of their disabilities, based upon appropriate medical and/or psychological documentation. This verification can address the legitimacy of reasonable absences. These requests for accommodations forms are delivered to faculty and provide a forum in which discussions of attendance and make-up policies and procedures can take place.
Students should listen closely to faculty announcements about attendance and make-up policies and procedures. Also, check your course syllabus for information about these issues. Each party should keep a written copy of what alterations may be decided upon with input from the student and the DS Coordinator.
An exception to the attendance policy does not mean that unlimited absences will be permitted or that other academic requirements of the course will be part of the exception. Students with disabilities are, as always, required to fulfill all course requirements and will be held to the same evaluation standard as other students in the course. As with all disability accommodations, exceptions to an attendance policy will be determined on an individual basis. The disability documentation must support this type of request. Accommodations are not retroactive.
Please call the DS Coordinator at 832-2281 if you have questions.


text:
Keeping your aquarium fish healthy is the hobbyist's number one priority. The Aquarium Health articles page is your source on FishChannel to find articles and information on how to keep your aquarium in a healthy state. You can read up on a variety of health related articles on such topics as marine aquarium algae water conditioners, maintaining aquarium filters to the role of aquarium carbon and how to avoid new tank syndrome. Establish a set schedule for water changes , filter maintenance and tank cleaning, and you'll experience years of enjoyment with your aquarium.
Freshwater aquarium hobbyists have to understand a range of conditions that can affect their aquariums, from issues such as aquarium snail invasions and freshwater algae, to high summer temperatures and water that is too hard.
Maintaining a marine aquarium takes a lot of dedication, education, and patience. The Saltwater conditions page offers up a wealth of information ranging from caring for the teeth of your pufferfish to marine nano tank issues, to testing for bacteria in the reef tan.
Disease prevention is important to maintaining a healthy tropical and marine aquarium. There are many diseases and conditions that can affect fish that are discussed on the Disease Information and Prevention page on FishChannel.
Choosing fish for your aquarium is often the most fun part of the aquarium fish hobby. As you choose fish to add to a new or established aquarium, you must first determine fish compatibility.
Hi, my tank is
Nature in a glass box.
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text:
Jill Dillard, who married Derick Dillard on June 21 in a family-filled wedding and a reception attended by more than 1,000 guests, says she's enjoying everything about being a new wife.
"I have the most amazing guy," the second daughter of Jim Bob, 48, and Michelle Duggar, 47, of TLC's hit reality show 19 Kids & Counting, tells PEOPLE. "Everything about being married is awesome."
The newlyweds spent their honeymoon at Kill Devil Hills, North Carolina, and rented a house on the beach, Jill, 23, exclusively reveals to PEOPLE.
Courtesy Jill and Derick Dillard
The newlyweds, who shared exclusive pics of their honeymoon with PEOPLE, toured the Wright Brothers National Memorial and packed a picnic lunch and spent an afternoon at Cape Hatteras Island, touring the lighthouse there.
"It was really pretty there," she says. "It was wonderful. We were able to be away for almost a full week."
Now that she's back, she's settling in to married life – setting up the couple's house together, officially changing her name and learning the art of cooking for only two.
Courtesy Jill and Derick Dillard
She also shared a pic on Instagram of her "sweet husband" pitching in by grilling their dinner.
The new Mrs. Dillard says that she and Derick, 25, have been spending as much time as they can together.
"Our house is really close to Derick's work," she says. "I have been able to drop him off in the morning and meet him for lunch so we can spend more time together. It has really been a lot of fun."


text:
on October 12, 2012 - 12:01 AM
, updated October 12, 2012 at 6:53 AM
The new report on the Buffalo Public Schools is a painful but honest look at the long-standing problems that are holding back students, and, in that, it is also a hopeful document. You can't fix what's wrong if you don't know what's wrong.
The report was prepared by distinguished educator Judy L. Elliott, who was appointed by the state to help turn around Buffalo's lowest-performing schools. She spent her first six weeks on the job visiting those schools (evidently a novel concept in Buffalo), speaking with central office administrators and exchanging information with the district's new superintendent, Pamela C. Brown.
Her conclusions were depressing, if not entirely surprising. What she found was that central office administrators had isolated themselves from the schools, ignoring requests for help or failing to respond adequately. All decision-making is concentrated in City Hall, not in the schools.
"Buffalo City School District is a centralized system that provides little school autonomy," Elliott wrote. "The structure of governance has historically yielded poor student outcomes. Priority school principals uniformly voice that they are disconnected, unguided and unsupported due to a lack of service and support from the central office."
That's not a finding, it's an indictment.
Other findings include failure to schedule principal meetings in 2011-12, little evidence of support and supervision of classroom instruction and high rates of student absenteeism, among other issues.
Brown collaborated on the report with Elliott, who came to many of the same conclusions, a heartening sign that they are on the right track. State Education Commissioner John B. King Jr., who appointed Elliott, approved the report, which included 39 steps meant to address the problems it details. Its recommendations mainly deal with providing training, reviewing data and providing written communications regarding specific issues.
Now it is up to Brown and the School Board to implement the solutions. The board is not required to follow Elliott's prescriptions, but it is required by the end of this month to submit a comprehensive improvement plan that is expected to incorporate those recommendations. If it doesn't, district officials will have to explain why. Parents, taxpayers and voters would be interested to hear those explanations.
The report is, by inference, a harsh criticism of the administration of former Superintendent James A. Williams and his predecessors. They concentrated authority in their offices and squelched the talents, creativity and passion of principals and teachers who are the boots on the ground.
But the report also stands as a condemnation of the School Board, itself, which left the superintendents it hired to administer the district in that oppressive way. Suffocation of talent does not qualify as strong leadership, and if the board didn't know its superintendents were pursuing that strategy, it should have.
The board has also been unwilling to do what good leaders do: set policy and expect administrators to implement it. In some sense, the central office was only following the example set in City Hall.
Fortunately, nearly anyone can learn from mistakes. Things have been so dysfunctional in this district for so long that insiders may not know the culture needs changing, let alone how to go about doing it. The School Board now has a golden opportunity to redeem itself and help lead the way toward improved education for Buffalo's children.
That work has begun. Brown has told principals they will become involved in filling teaching and administrative positions in their schools – a significant development – and plans are under way to hold principal meetings.
It's a start, but there is a long way to go. Elliott's initial contribution shows a way forward.


text:
1/22 GDT : Stars 2 at Red Wings 1
Posted 22 January 2013 - 11:12 AM
- hillbillywingsfan, 55fan and Cloune like this
"All done? Five bucks." - Pavel Datsyuk after an interview
"Very few cities in the NHL have the history or the following of the Detroit Red Wings." - Steve Yzerman
Be sure and check out my writing on Detroit Sports Nation
Posted 22 January 2013 - 11:13 AM
AWESOME!!! can't wait for this game. My buddy is a Dallas fan so this one will be good.
Edited by hillbillywingsfan, 22 January 2013 - 11:13 AM.
Posted 22 January 2013 - 11:16 AM
Rofl, we can basically field a line with simply injured players. That category does not look pretty at all, luckily we'll have helmer and bert back Friday. BIG GAME TONIGHT BOYS BIG GAME BIG GAME. I'm excited to see how they play their first back-to-back game of the season. I think the crowd at the Joe carry the Wings to a 4-2 wing over the Dallas Stars. Brunner, Smith, Cleary and Sammy have goals for Detroit.
Also, upcoming schedule shows the Dallas stars on the 29th, but it displays that we're playing Minn via text.
Pavel Datsyuk - "Pasha" - #13
"Got no fun if you got no puck"
'"I like ladies" - Towards the Lady Byng trophy
"Okay $5 now"
I'm Don Cherry and Danny DeKeyser is my Kadri.
#4 Guest_The Axe (Guest)
Posted 22 January 2013 - 11:33 AM
Posted 22 January 2013 - 11:39 AM
Per Ansar KHAAAAAAN!!! Goose is in for Sammy tonight...
Nyquist recalled from GR, playing with Fil and Franzen tonight. Samuelsson (groin) out
- Rick D likes this
"We thought we were indestructible, The Lords of Iron"
Posted 22 January 2013 - 11:40 AM
Nyquist up from GR & in for Sammy tonight per Kahn:
Sammy out pulling his groin.
Edit: And so this isn't just a repeat, Babs has evidently confirmed that the Wings have signed a D-man. Name still pending though but it appears Chris Campoli's name is the one that's coming up the most.
Edited by ogreslayer, 22 January 2013 - 11:46 AM.
Posted 22 January 2013 - 11:43 AM
Posted 22 January 2013 - 11:46 AM
Aaaww yeah Gus replacing Sammy, can't wait to see him in action!
-Steve Yzerman
Posted 22 January 2013 - 11:47 AM
Today is my parents' 41st wedding anniversary. As a treat, I'd like it if the player whose number is closest to 41 gets a hat trick. That would be our new captain, Mr. Zetterberg.
- 55fan likes this
"People assume that time is a strict progression of cause to effect, but *actually* from a non-linear, non-subjective viewpoint - it's more like a big ball of wibbly wobbly... time-y wimey... stuff." -- The Doctor
Posted 22 January 2013 - 11:50 AM
Call up Ouelette for tonight.

Since he is still in juniors tis not gonna happen sir.
Posted 22 January 2013 - 12:00 PM
I will continue in wait-and-see mode until the Zombie line gets healthy. Stupid penalties against CBJ put them back in the game, and Z was one of the offenders. He needs to recognize his leadership sets an example.
Jagr was adored for his play against the Coyotes, but against a GOOD team (Minnie), he only got 3 shots on goal. Meh.
Wings, 2-1.
Posted 22 January 2013 - 12:09 PM
Brunner gets his first,
Pavel gets the winner,
kronner and mule get one each.
Nyq with a couple helpers,
same with Pavel and Z.
Tootoo fights ott.... Oh, wait..
Dat·syu·ki·an [dat-soo-kee-uh n]
1. When your moves are so amazing and beyond reason, the only way to describe them is "datsyukian."
Posted 22 January 2013 - 12:11 PM
Datsyuk really going to center that first line??
Sounds like a good idea to me.
It didn't make sense that they were putting him in to win face-offs last night, but he wasn't even taking face-offs on his own line.
Posted 22 January 2013 - 12:14 PM
Pumped to see Nyquist up with the team. Not a huge fan of sticking him with Flip and Mule but we will see how it works
I would role the lines
But at this point I am just happy to see Nyquist. Here is hoping he plays well enough that they can't send him back down
- puckloo39 likes this
Posted 22 January 2013 - 12:46 PM
Lets keep the momentum going! LGW
Posted 22 January 2013 - 12:47 PM
Hockeytown0001 GDT is absolutely a BEAUTY!!!!!!
Posted 22 January 2013 - 01:03 PM
Huskins in tonight, per Holland.
Posted 22 January 2013 - 01:06 PM
Given our amount of injuries we need to take advantage of any slim chance we get, and there is no better way to do that than make home ice at the Joe a fortress for the shortened season; just like we did with our winning streak last year.
This is a game we should be winning on paper. Granted Jagr is there but other than that nothing jumps out.
In the off-season they acquired:
C Cody Earkin, RW Jaromir Jagr, Backup G Cristopher Nihlstorp, D Aaron Rome, C Derek Roy, RW Reilly Smith, and LW Ray Whitney.
Earkin had his breakout season in the NHL last year where he played 30 games for the Capitals with 8 points. Nihlstorp came from Sweden and is an NHL rookie at 28. Given Lethonen is there I doubt he will get much time. Aaron Rome comes from the Canucks where he played 43 games and had 10 points with only 1 game played in the playoffs. Derek Roy is an established NHL winger playing more than 70 games per season (barring 2010) for 7 seasons with the Sabres. This is his second NHL team. His career year was in 2007-08 when he had 81 points. His productivity has steadily decreased since then with 44 points last year.
Reilly Smith is a brand new rookie having been drafted 2 years ago. He has only played in 3 NHL games. Lastly Ray Whitney is a veteran and a former Red Wing (03-04 season). He is coming off a 2nd best career year at Phoneix with 77 points. He also had 7 points in the playoffs. At 40 he is looking to finish his career on a high note.
All in all it seems Jagr, Whitney, and Roy are the players they have bet on this season. 2 are NHL veterans in Jagr and Whitney and Roy is a solid scorer who will lead the first line at center.
I like this match up a lot. We swept them in all 4 games last season and it's time to continue the tradition.
Edited by Russian Houdini, 22 January 2013 - 01:08 PM.
Posted 22 January 2013 - 01:11 PM
I think this game needs to be the time that Franzen steps it up for us and starts putting biscuits in baskets
- Rick D likes this
Posted 22 January 2013 - 01:33 PM
Call up Ouelette for tonight.you can't call up a guy in the CHL.
HankthaTank - Squirrels, they hate to be thrown. / Why is the magical unicorn named Brian... Jedi - I just downloaded the "kids" book, "Go the F--k to Sleep" as narrated by Samuel L. Jackson on my kindle. I am now ready to be a daddy. / *Checks Router* No, I'm positive I didn't hit the "Wings Defense Sucks" button. Electrophile - I'm just glad the Wings were able to win despite the Curse of Brian. ACallToArms - I think Trey needs to put something about payroll tax and deferred income in his sig... Edicius - I'd rather [have] a soundbite of me saying "I like (man sausage)" rather than "I like Crosby".
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MVB Earns 3-0 Sweep of Barton to Remain Undefeated
WILSON, N.C. – The Ball State Cardinals earned a 3-0 (25-15, 25-12, 25-13) sweep of the Barton College Bulldogs Saturday afternoon at Wilson Gymnasium. With the win the Cardinals improve to 5-0 on the year. Bobby Renaud, Marcin Niemczewski and Jon Clawson all saw action for the first time this season in the match.
Senior outside attacker Jamion Hartley led the way for the Cardinals with a season-high 10 kills and a .471 hitting percentage (10-2-17). Junior outside attacker Urim Demirovski notched a career-high nine kills and two service aces on the match. Demirovski hit at .538 (9-2-13) and added a solo block and an assisted block.
Sophomore middle attacker Julian Welsh-White also had a career match, blasting seven kills for a .778 (7-0-9). Sophomore outside attacker David Ryan Vander Meer had a career-high four kills to with his career-high three service aces and 11 digs. Senior setter Dan Wichmann tallied a season-high 34 assists to go with two kills, five digs and a solo block.
Freshman libero Bobby Renaud got his first career start and had two assists and eight digs. Freshman outside hitter Marcin Niemczewski and sophomore middle attacker Jon Clawson added six kills each.
The Cardinals outhit the Bulldogs .579 (45-7-66) to .132 (22-13-68) and held the advantage in digs (28-12), service aces (6-2), assists (43-21) and blocks (6-1).
Ball State was the first Division I program Barton College has ever faced. The Bulldogs now drop to 0-4 on the season.
The Cardinals will return to Worthen Arena next weekend to open up a five-match home stand. Ball State will host Quincy on Friday, Feb. 1 and Lindenwood on Saturday, Feb. 2. Both matches are scheduled for 7:30 p.m. Be sure to follow the team on Twitter at @BallStateMVB or on Facebook at "Ball State Men's Volleyball". As always, ballstatesports.com is the official website for Ball State Athletics.


text:
on December 21, 2012 - 1:00 AM
UB medical students must meet key criteria
As the director of medical student admissions at the University at Buffalo School of Medicine and Biomedical Sciences, I am writing in response to a recent letter from one of your readers who had stated that the school accepts students who are not U.S. citizens. I want to make it very clear that our medical school will only accept students who are either U.S. citizens or permanent residents. Although other schools of the university may vary in their admissions policies, the medical school will not even review applications from individuals who do not meet the above categories.
Earning an interview as well as admission to our medical school has become extremely competitive. Our Admissions Committee examines multiple factors when considering whom to invite for an interview and subsequently accept. A Medical College Admissions Test score is only one. Science and non-science grade point averages, extracurricular activities, activities related to patient care, letters of recommendation, etc., all play a role in our review process. Although not every Western New York student who applies is successful in gaining admission, the fact that an applicant is from this region is taken into account throughout the entire admission process.
Charles M. Severin, M.D.


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Microsoft DevRadio: Developing for Windows 8 in 1/2 the time (Part1) Getting Started
- Posted: Jul 25, 2012 at 9:31AM
- 2 comments
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Developer Evangelist, Michael Palermo kicks off his new series today where he shows us how we can develop for Windows 8 in under 4 minutes or less. Today's topic? How to get started developing your Windows 8 app by downloading and using Visual Studio Express.
Next Steps:
Step #1 – Download the Tools for Windows 8 App Development
Step #2 – Download Visual Studio Express for Windows 8
Step #3 – Start building your own Apps for Windows 8
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After five days of searching, Malaysian authorities say there is still no sign of Malaysia Airline flight 370, that was en route to Kuala Lumpur to Beijing when it disappeared from radar. The massive, multinational search has been extended to cover more territory west of the plane's intended flight path. Sally Kidd follows the latest developments from Washington.
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SHEPHERDSTOWN - Neither Louisa Entsminger nor Carrie Dunham had met prior to attending Saturday's Eastern Panhandle Home School Conference, but soon they were chatting like old friends.
That's because both women are new to home schooling their children and eager to learn about local resources to help in that effort.
Take a local home schooling co-op that helps parents network about extracurricular activities, curriculum materials and assistance in specific subjects such as math or science.
Entsminger, who had already taken advantage of the service, didn't have to urge Dunham very much before she was equally excited about getting involved with it too.
"It sounds kind of silly, but this is really part of the value with a conference like this, because you get to meet and network with other people who are having the same experiences as your family. It is great to know I can get started now with the co-op because I thought I had to wait till September, so I really appreciate this," she said with a smile at Entsminger.
Since she had been home schooled, Entsminger said she is eager to share this experience - such as being able to work at an individual pace and being closely involved in the educational process- with her children.
"It is a lot of work, but the benefits are easy to see," Entsminger said.
Approximately 140 individuals attended the session, which had been organized by home school groups in Berkeley and Jefferson counties, said chairman Donna Bent. The conference provided more than a dozen speakers and classes aimed at helping home school parents - whether they were new to the activity or had been doing it for years, Bent said.
A popular early morning session featured keynote speaker Vicki Bentley "who is the mother of eight daughters, foster mom of over 50 children and a grandma to 17 wonderful grandbabies. So she has homeschooled 17 children since 1988," Bent said.
No stranger to home schooling, Bent said neither of her daughters has ever attended public schools. Her eldest daughter is now in college, living in an apartment and enjoying the classroom experience, Bent said.
"We are very proud of her for many reasons. But I also think she represents the children who are home schooled because they typically do love to learn and often excel. However, they are also busy in extracurricular activities and ready to continue being active when they get a little older," she said.
Brittany Miller, who is being taught by her mother Kathy, had nothing but praise for this educational option and expects to one day home school her own children.
"Of course, there is kind of a balance because sometimes she's Mom and there's time for fun. But then again, when she's my teacher, that's the time to get serious and learn," Miller said.
Being able to learn at her own pace is important, according to Miller, who said she excels at history but not English.
"This way we can do what I need and what is best for me," she said.
Conference sessions coordinator Denise Beaty, a former teacher who is home schooling four children, readily acknowledged that sacrifices are often necessary to do this successfully.
"But they are my children, so it is definitely a labor of love,"Beaty said.
Beaty said she enjoyed helping with the conference because it is a resource for other home schooling parents.
"Getting started can be a little intimidating, so it is good to know that others are here for you and they've been where you are now. They know what has - and hasn't - worked for them and what they might suggest doing differently. It's all about the best educational experience for our kids," she said.
Dusty and Sara Catlett had different childhood experiences since he went to public schools and she was home schooled. But they were more sure than ever by Saturday afternoon that home schooling their children was the right choice, especially after having an opportunity to talk to other parents and look at curriculum materials.
Still, it won't always be easy to know what's right for their four-year-old son, they agreed.
"That's the great thing, however, because if something doesn't work, you can try another way until it is a good fit. Our son has a lot of energy, so that's something we'll take into consideration, but we'll be able to do it if he's home schooled," she said.
- Staff writer Jenni Vincent can be reached at 304-263-8931, ext. 131 or email@example.com.


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8, rue de Richelieu
75001 Paris, France
Fall in love with La Clef Louvre Paris, one of the most sought-after addresses in Paris. As part of a unique Parisian collection of boutique serviced residences, La Clef Louvre Paris epitomises contemporary chic living in the heart of one of the most vibrant parts of Paris.
Located opposite the Comédie-Française theatre and the Grand Louvre museum, and only a few minutes away from the Opéra, this distinctive neighbourhood offers a mix of high-end contemporary shopping venues, quaint cafes and cultural attractions. Indulge in luxury offerings of branded boutiques at Faubourg Saint-Honoré and then relaxing at café Angelina with delightful hot chocolate and mouth-watering French pastries. Drop your shopping bags back at your suite before taking in a bit of culture at l'Orangerie or the Musée d'Orsay art museums.
La Clef Louvre Paris is, in itself, a beautiful work of art. Built in 1908, it features an Art Nouveau façade made from dressed-stone, adorned with balconies, sculptures and colonnades, a perfect complement to the immaculately designed suites – your haven in the city.
Absolute must-see: The Printemps department store has a new luxury venue at Le Carrousel du Louvre. These majestic, elegant premises occupy 2,600 m² and are home to prestige luxury and beauty brands representing the art of making fine leather goods, watches, jewelry and fragrances.
There is no better location in Paris. You're right next to the Comédie-Française, a stone's throw from the Louvre, the Tuileries gardens and the banks of the River Seine are only a five minute walk away. Be spoilt for choice at the gardens of the Palais-Royal with their arcades and many restaurants, just across the road from the residence. The area is home to numerous boutiques and restaurants stretching from Avenue de l'Opéra, along Rue Saint-Honoré and around Place Vendôme to Rue de Rivoli. Business travellers will appreciate being so close to the business district located between the Opera House and the Paris Stock Exchange, as well as convenient connections with popular places of interest throughout Paris.
Each suite offers high quality bedding, a fully equipped kitchen, fine tableware, a Nespresso® coffee maker, Wi-Fi, and iPod/iPad® docking stations. Most of suites are equipped with a washing machine and dryer. Technological sophistication combined with the elegance of contemporary décor, as well as the thoughtful attention given to welcome amenities guarantee you the utmost level of comfort.
Added facilities and services like the fitness centre, concierge and limousine service, gourmet breakfasts, and even the option to have your refrigerator filled with food on your arrival, ensure your peace of mind that everything you need is right at your fingertips. And this is just our way of making you feel right at home, always.


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Editor's note: Journal Junction offers the public a forum to applaud successes, discuss issues, point out problems and review the events of the day in a constructive manner. Journal Junction comments should be limited to two to four sentences and be no longer than 80 words. Longer comments should be submitted as "Letters to the Editor," which is a separate forum. The Journal's classified ads section offers help to those with lost or found items. This is a sampling of comments received today. Any others, subject to editing, are published in the online Journal Junction at www.journal-news.net under opinions.
From Tomahawk:
I think it's about time that we leave the election that's already been won and lost, and move forward to back Sen. Manchin in protesting about MTV's forthcoming reality show about West Virginia, which will make us look like a bunch of idiots and fools. It's an embarrassing and not real show that's coming in the near future. The election is over. Let's move forward and do something constructive.
From Winchester:
To the Shepherdstown caller: I'm a 60-year-old overweight, gray-haired male. Cashiers can call me "sweetie" and "honey" as often as they would like. Makes my day.
From Jefferson County:
Thank you, Joe Manchin, for standing up for your state, our state, where these reality shows are trying to desecrate the character and people of West Virginia, where so many others from the surrounding areas are moving in. How do we find out how to sign a petition to stop this?
From Harpers Ferry:
To Shepherdstown: Honey, Sweetie and Darling are polite southern terms used when one doesn't know your name, here are two other polite southern terms "Isn't that special?" and "Aren't you special?".
From Inwood:
Nothing is wrong with saying, Happy Holidays, unless you are obligated to say it because you will surely offend people otherwise. It seems we cannot say anything nowadays without offending someone, but then how dim are we? Merry Christmas.
From Shenandoah
To Shepherdstown who is really tired of being called "honey" or even worse "sweetie" by cashiers. Personally, I think it is very nice when they do and it makes my day. I can think of a lot of worse things to call customers. Let me guess - you are a "transplant."
From Bunker Hill:
To the Bunker Hill parent who is upset over the mulch on the playground: I wonder, did you really measure it? You should wrap your child in bubble wrap so he won't get hurt. By the way, the basketball court and the track don't have mulch on them either. I feel sorry for this generation of sissy parents. I am 75 years old.
From Darkesville:
There can be no immigration "reform". No compromise Shelly Moore, ya here? We lost this election because there weren't enough angry white men. Well, it's obvious we gotta limit voting to rich white men - men who know what's best for the country.
From Charles Town:
Before starting a dual lane W.Va. 9 to Berkeley Springs please consider attaching W.Va. 9 on the north end of town. This would give relief to the congestion on the south end (I-81) and establish a bypass on the east end to meet W.Va. 9 on the north end of Martinsburg. It also relieve congestion in town from traffic coming to and from Shepherdstown.
From Bunker Hill:
Charles Town knows how to help with Christmas shopping in down town in fact they do it year round Washington Street in Charles Town has two-hour free parking every day. What's up with Martinsburg, why can't they do same? They ask us to shop downtown but do nothing to help us. I guess they need that 25 cents from the parking more.
From Martinsburg:
We need to throw the GOP over the cliff!
From Morgan County:
To quote a recent Martinsburg caller, "I see nothing but liberal Junction postings." He/she is spot on. Has nothing to do with conservatives' literacy however. Has everything to do with the Junction editor's political ideology. Proof of lack of reason, however, is liberals' moronic insistence on pursuing Spain's and Greece's model of social spending while watching it lead to chaos and collapse there.
From Harpers Ferry:
The Christmas spirit is alive and well at the Old Opera House. A four-star, standing ovation production of Scrooge. Go see it!
From Martinsburg:
At age 82, I remember being told that since my youth, that there are more mentally deficient citizens walking our streets than those institutionalized. Certain proof of this political activies inside the Washington Beltway. What we have seen the past four years confirms the success of our liberal, socialist press and education system, for the past half-century, at altering American values.


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on May 22, 2013 - 1:06 AM
, updated May 22, 2013 at 2:19 AM
An attempt to exceed a cap on school taxes in Lewiston-Porter failed Tuesday, while voters in Wilson and Niagara Wheatfield also defeated spending plans that would have increased taxes.
Early election results showed more than half of the school budgets in Erie and Niagara counties gained voter approval, including the first school tax increase in Niagara Falls in two decades.
But in Lewiston-Porter, where the 23 job cuts were not enough to make up for lost revenue, voters thought a 5.52 percent increase in tax revenue was just too much. The proposed tax hike would have exceeded the state's limit on tax increases in the district for the 2013-14 school year.
"I think the state should pick up the slack," said Dick Marino, a Lewiston resident and one of a number of retirees who said he did not support the tax increase. "I don't support a budget like that."
Voters in all but two of the 37 school districts in Erie and Niagara counties that held elections on Tuesday were faced with budgets that increased the amount of taxes collected. In many districts, those tax increases were proposed along with budget cuts to make up for a steep increase in teacher pension costs and state aid that remains lower than three years ago.
Despite those tax increases, voters in 20 districts approved school spending plans, according to early results.
In Niagara Falls, where the district has used layoffs and other budget cuts to keep taxes flat for two decades, voters approved a budget that would increase taxes by 3 percent.
"To me, that's not large, compared to what it could be," said Mary Ruth Davis, a Niagara Falls resident.
But residents in the Falls also voted out two longtime incumbents, Kevin Dobbs and Don J. King.
School administrators in Niagara Wheatfield struggled to draw up a budget within the district's 5.91 percent tax cap this year. The strategy appeared to have failed. The Niagara Wheatfield budget was defeated by three votes.
After briefly considering making changes to the district's kindergarten program, school board members in Niagara Wheatfield settled on a budget proposal that cut six teaching positions. But school board members had said more programs would go if they had to pare down the budget to eliminate a tax increase.
School districts where budget proposals were defeated Tuesday can present the same budget or a revised version to voters in June. If the second vote fails, they must adopt a contingency budget that does not raise the amount of taxes collected.
Lewiston-Porter Superintendent Chris Roser, speaking before the budget vote, said he anticipated the Lewiston-Porter School Board would work toward crafting a new budget that remained within the state's tax cap. That would mean about $500,000 in additional budget cuts, he said.
"I doubt very much they'll want to put the contingency out there at this point, because the contingency would mean $1.7 million more cuts," Roser said before the budget vote. "And that would just be, wow. That would be unbelievable."
A steady stream of residents came in to vote at the Lewiston-Porter School District on Tuesday afternoon, with strong opinions both for and against the $40 million budget.
"I have no difficulties supporting public education, that's what makes democracy flow," said Paul Dominick, of Youngstown, a retired college professor.
Many voters who opposed school budgets were focused on taxes, while others expressed concern about the types of programs that would be cut if school budgets failed.
Barbara Smyton, a retired elementary school teacher from Youngstown, was among those who supported the budget in Lewiston-Porter despite the fact it exceeded the district's tax cap.
"Whatever the children need," Smyton said. "The kids are the future of America. We need to be there for them. I can understand if you are on a very fixed income it is hard to see these taxes be raised, but here we are fortunate and can afford this."
Abby Mitchell of Youngstown, a mother with children who will soon be attending school in Lewiston-Porter, gave the district's budget a thumbs down.
"Too high," Mitchell said. "They need to cut back like everybody else." Niagara County school district election results:
• Candidates (elect two): Mary Jo Clemens-Harris; William Smith (i). Final vote tally not available.
• Budget: Yes, 298; No, 95.
• Proposition 2: Proposal to convert Barker Free Library into a school district library with a $75,000 budget: Yes, 276; No, 128.
• Proposition 3: Candidates for Library Board (elect seven): Roy Anderson, James Trinder, Pamela Atwater, Terrence Upton, Henry Charache, Marilyn Zaciewski and Seanna Corwin-Bradley.
• Candidates (elect three): Jodee L. Riordan, 1,297; Anna Boulay Wright, 1,301; Betty VanDenBosch Warrick, 1,239.
• Budget: Yes, 939; No, 1,153.
• Proposition 2: Authorize a $26 million capital improvement project for interior and exterior reconstruction and renovation work for code and safety measures and upgrades throughout the district, as well as a number of enhancements and upgrades including the pool and locker room and air conditioning for the computer labs: Yes, 1,167; No, 923.
• Budget: Yes, 1,158; No, 596.
• Candidates (Elect three): Marietta Schrader, 868; Todd McNall, 864; Diane Phelps, 853; Edward Sandell, 832; Jon Williams, 700; Randall Parker, 551.
• Proposition 2: Authorize a $22.2 million capital project package including improvements to the kitchens of four elementary schools, and added security cameras and upgraded Internet connections and fiber optic cable at all schools: Yes, 1,097; No, 606.
• Candidates (elect three): James Schmitt, 675; Donna Lakes, 666; Michele Malone, 538; Joseph Flagler, 520; Margaux Lingle, 504.
• Budget: Yes, 646; No, 416.
Niagara Falls
• Candidates (elect two): Anthony F. Paretto, 1,076; Ronald J. Barstys, 957; Kevin Dobbs (i), 879; Don J. King (i), 716; Herbert L. Lewis, 481; Michael S. Gawel, 343;
• Budget: Yes, 1,396; No, 975.
Niagara Wheatfield
• Candidates (elect two): Lori Pittman, 1,876; Amy Deull, 1,807; Lorna Tilley-Peltier, 1,357.
• Budget: Yes, 1,598; No, 1,601.
• Proposition 2: Allow a representative from the high school senior class to sit on the School Board as a member who would not have voting rights or be allowed to attend executive sessions: Yes, 1,855; No, 1,107.
• Candidates (elect four): Michael D. Zimmerman, 598; Dennis P. Toth, 569; Kevin P. Duffy, 508; Jeffrey D. Duncan, 440; Susan M. Brooks, 419; Sherri Weber, 361; Andrea L. Wick, 314; Eugene E. Stanwich, 186.
• Budget: Yes, 622; No, 332.
• Candidates (elect two): Mark Randall, 654; Amy Phillips, 647; Timothy Kropp (i), 637.
• Budget: Yes, 414; No, 698.
News Staff Reporters Charlie Specht, Thomas Prohaska, Nancy Fischer and Aaron Besecker contributed to this report. email: email@example.com


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Townhome Specialist
Northwest Home Designing, Inc is highly recognized for our townhome projects. For the last four decades, our duplex and townhomes have been used to create some of the northwest's most successful planned communities. Our duplex and townhomes maximize space without sacrificing design style. For more information regarding our townhome designs or custom townhome project, contact our "Townhome Specialist", Robert T. Mickey, AIA; he can make your planned community projects an overnight success.


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Systemwide Events Calendar
Leeward Career, College & Job FairApril 11, 9:00am - 1:00pm
Leeward Campus, Learning Commons Concourse
In its 11th year, the Career, College & Job Fair is the largest of its kind on Leeward Oahu. About 80 recruiters are expected at the Fair, open to the general public. A separate program will educate students from Central and Leeward Oahu schools on college and career preparedness.
Attendance is free for job-seekers. Young children are discouraged from attending. A list of participating employers and college programs will be listed on the Leeward CC Job Prep Services website below. For more information, contact the Leeward Job Prep Services office at (808)455-0240.
Event Sponsor
Job Prep Services, Leeward Campus
More Information
Job Prep Services, 455-0240, firstname.lastname@example.com, http://www.leeward.hawaii.edu/jobs-events
|Thursday, April 11
|The Wellness Center - Fitness Class Schedule
Maui Campus, Pilina Bldg., Wellness Center
|Leeward Career, College & Job Fair
Leeward Campus, Learning Commons Concourse
|"'Hermaphrodite Embassy': Gender and French Diplomacy in the Reign of Louis XIV
Manoa Campus, Henke 325
|Wyatt Nagao, trumpet
Manoa Campus, Orvis Auditorium
|Special Microbiology Seminar
Manoa Campus, MSB 114
|Rising Atmospheric CO2 and Ocean Acidification
Manoa Campus, MSB 100
|"Japanese Religions, Popular Culture and the Media" by Elisabetta Porcu
Manoa Campus, Tokioka Room (Moore Hall 319)
|Tunnel of Oppression
Manoa Campus, Frear Hall
|PAMI Chinese Innovation Strategies Lecture (FREE)
Manoa Campus, Shidler College of Business Room D-204
|Chess Club
Manoa Campus, Campus center room 308
|Taste of Manoa Spring 2013
Manoa Campus, Campus Center
|Graduate Composers' Symposium
Manoa Campus, Orvis Auditorium
- Highlighted dates have scheduled events.
- Select the date to view all events for that day.


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Skateboarding and music can be a positive force for change. A portion of the proceeds from these decks will be donated to Children's Hospital & Research Center Oakland.
Children's Hospital & Research Center Oakland is the Bay Area's only independent children's hospital. For over 100 years, It's been Children's Oakland's mission to take care of every child who needs help, regardless of ability to pay.
For more info please visit: www.childrenshospitaloakland.org
You can pick up a board here: http://store.adelinerecords.net


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Resort Report for Alpine Meadows
Address: 2600 Alpine Meadows Rd Tahoe City, 96145
Resort URL: http://dyn.onthesnow.com/c/l?a=3633&u=http://www.skialpine.com
Resort Email: firstname.lastname@example.com
Snow Phone: 530-581-8374
Main Phone: 530-583-4232
Projected Opening: OPEN
Projected Closing: 2010-04-19
Number of Acres: 2400
Snow Making Acres: 800
Top Elevation: 8637 FT
Base Elevation: 6835 FT
Vertical Feet: 1802 FT
Number of Lifts: 14
Number Double Chairs: 5
Number Surface Lifts: 3
Total Lift Capacity: 16050
Average Snowfall (IN): 365 IN
Number of Runs: 100
Advanced Runs: 35
Intermediate Runs: 40
Beginner Runs: 25
Ski: yes
Snowboard: yes
Cross Country: no
Ask anyone who has been there what they remember about Alpine Meadows and they'll tell you: great snow and soaring views of Lake Tahoe and the High Sierra. With 2,400 skiable acres, Alpine has enough to keep even the most adventurous powder hound happy for days. Alpine was the first in the West to install a six-passenger high speed chair and has done much to keep generations of skiers coming back for more. Alpine is also home to a fine adaptive ski school for disabled skiers and boarders. You can get there by air via Reno-Tahoe International Airport, 45 miles Northeast via all-weather Interstate 80. Sacramento International Airport, 90 miles West of Truckee, Calif., via all-weather Interstate 80.
Lodging within one mile of ski resort. Additional lodging in North Lake Tahoe, only six miles away. Fully contained campers are allowed. Lift and lodging packages are available. The nearby Tahoe Biltmore offers guests a chance to try their luck at the hotel casino, entertainment, and affordable room rates. There's a free daily shuttle service to and from Alpine Meadows.
Cross country, touring, helicopter, tennis, mountaineering, theater, sledding, snowmobiling, tobogganing nearby, NASTAR, snowboarding, and snowshoeing.


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Top Definition
A repulsive scent creeping from an unkempt vagina, usually causing a burning sensation in the eyes as one attempts to muff dive. Serious cases may cause skin irritation.
My lungs almost caved in when I got a whiff of that stank puss, it made me want to eat her ass.
Close your legs; your stank puss is coming out of your jeans.
Close your legs; your stank puss is coming out of your jeans.
Por guardo 16 de diciembre de 2003
Trending Now
Can you define these popular missing words?
A pussy in desperate need of a douche. Smells really bad
"Yo my dick smells like shit cause of that stankpuss!"
Por Frank Sidor 11 de noviembre de 2005
a girls pussy that smells REALLY bad (often used as a derogatory comment)
After Daniel fingered his girlfriend Kandy, he noticed that his finger still smelled horrible the next day and said "Damn that girl has got some major stankpuss!"
Por themasterofsexdefinitions 15 de febrero de 2004


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Name: Darby Lee
School: Altoona
Age: 17
Grade: Senior
Sport: Basketball
Athlete of the week achievement: Lee scored 21 points and grabbed 13 rebounds in Altoona's 67-58 victory at Central Dauphin East on Saturday.
Season update: Lee is averaging 12.4 points and six rebounds per game for the 3-5 Lady Lions.
Coach Jill Helsel's quote: "She played a complete game against CD East. She rebounded well offensively and went strong to the basket. She led the team, I thought, very well. Overall, I think she's handled everything well so far this season. Teams are keying on her, and she's figured out how to get her points and rebounds in a different way than last year.''
Favorite teacher: Mr. Lowe
Favorite subject: Biology
Favorite movie: "Pirates of the Caribbean'' and "The Hunger Games''
Favorite food: Randy Hatch's famous chili
Favorite song: "Dark Horse'' by Katy Perry
Outside interests: Snowboarding, going to the lake, knee boarding
Favorite professional team: UFC's Team Silva
Favorite college team: Hartford Hawks
Pro athlete most admired: Shaun White
Best athlete I ever played with: McKenzie Hatch
Best athlete I ever competed against: "I played against two 6-foot-4 twins from Canada over the summer.''
Most influential person on my athletic career: My family
Proudest athletic achievement: My full scholarship to the University of Hartford
How I got my start in basketball: "When I was little, my dad put me in a league and taught me from there.''
Future goal: "Win the District 6 championship, states and make all-state.''


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Chest Guard: Liberty Reversible TKD Chest Protector$34.99
Our Liberty TKD Chest protector is constructed of high-density foam with a soft vinyl shell. It is reversible, showing red score points on one side and blue on the other. This is great for practicing sparring and will provide plenty of protection even for official Tae Kwon Do sparring.
- Durable, high-density foam that absorbs impact
- Soft, vinyl cover
- Red TKD scoring zones on one side, blue TKD scoring zones on the other side
- Special shape designed to fit almost any body type
- Easy on & off styling, with adjustable straps
Chest Guard: Liberty Pro Foam Sparring Chest Protection$39.99
This piece of protective training equipment is designed specifically for mixed martial arts training. Liberty's Pro Foam Chest protector features custom impact reduction foam padding to allow all mixed martial artists to train at full force with the equivalent safety of a boxing glove, minus the bulk. Liberty's Pro Foam Chest protector comes in sizes Small through Large and also comes in three colors; White, Black and Red. Own the proper mixed martial arts training equipment that will put you on the fast track to success in the octagon.
- 1/2" foam base construction
- Second 1/2" foam layer covers solar plexus area for added safety
- Will help disperse impact from any kick or punch from any martial artist
- Adjustable straps makes it easy to put on and off
Chest Guard: Bushido Female Chest Protector$19.99
- This female Chest Protector sports bra can be worn with or without protective cups
- Approved for competition
- Allows movability while training
- Colors: White
- Sizes: S, M, L, XL
Size Bra Cup
Small 30"-32" A Cup
Medium 34"-35" B Cup
Large 36"-37" C Cup
X-Large 38"-40" D CupLearn More
Women's Chest Protector$19.99
This women's chest protector has a durable PVC shell with cotton inlay for added comfort. Located in the rear are shoulder straps for stability. With Velcro enclosure's, this Women's Chest Protector comes in sizes small through Extra Large in color white. A protective necessity for the female Martial Arts practitioners.
- PVC Shell with Cotton inlay
- Rear shoulder straps for stability
- Color - White
- Available in small, medium, large and extra larg
Size Bra Cup
Small 30"-32" A Cup
Medium 34"-35" B Cup
Large 36"-37" C Cup
X-Large 38"-40" D Cup


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Z-Rock Jeff
I've been Rockin' with Southern Minnesota since 2008. It's been a great ride and we're looking forward to many more years of bringing GREAT bands to Rochester. So far we've had: Pop Evil Shinedown Bush Chevelle Halestorm Hinder nonpoint Hellyeah Staind Seether Buckcherry Rob Zombie Alice Cooper and MANY more. Not to mention the greatest rock festival in the Midwest, ROCK FEST in Cadott, WI!! Catch me, afternoons from 2-7 on Z-Rock! With the 3some at 3, the "Work Release Program" and more!


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As Immunotherapy Revolutionizes the Cancer Treatment...
NSCLC is "Major Battlefield" as Merck,...
Developers of DTC Genetic Testing Are...
Expanding Use of NGS Has Largely...
Synthetic biology has advanced in leaps and bounds in recent years, with innovations ranging from re-engineered genomes to improved crop strains and DNA as a data storage device. The latest game-changer comes in the form of next-generation gene synthesis, which delivers highly accurate constructs at significantly lower prices and in far greater numbers than has been possible to date.
To learn more, GEN sat down with some of the founders and advisors of Gen9, the Cambridge, MA-based company that has commercialized this high-throughput gene synthesis technology. We spoke with:
Endy: As a type of object in the world, DNA is one of the more important. It is responsible for coding most of the living world; it's the molecule that's right at the center of biology. DNA synthesis allows you to construct DNA from scratch, so that's an important technology. It's shocking how little work has gone into getting better at building DNA.
From a different perspective, we currently do not understand most of the biology on the planet. It's one thing to take a system apart and try to understand its components—you learn by doing that. But another very powerful way of learning is to tinker: to perturb it, to poke and prod and change something and see what it does. With synthetic biology you can make DNA that encodes perturbations and put them back in natural systems to see how they behave.
Church: There are two main applications: pathway engineering and genome engineering. There are probably many more people today doing biochemical pathway engineering, but the genome engineering is also very interesting. Pathway engineering tends to be about libraries while genome engineering tends to be about making a fairly specific goal.
For pathways, what you want to do is gather together pieces of DNA from all over the biosphere that have the right components and make libraries. You fairly quickly get up to a large library size and the application is making large amounts of a chemical or a pharmaceutical or a fuel or something like that. You're screening for the DNA molecule that confers the best type of enzyme and the best level of enzyme to achieve something.
With genome engineering you generally have a more specific goal for your genome and typically the changes are more scattered about the genome. So far, these new genomes aren't that different from the original genomes, due to uncertainty about proper functioning as you get too far from the original. Combinatorial complexity could be valuable here, too.
Endy: We see a lot of people building DNA to help them discover and invent therapeutic molecules, enzymes so they can make chemicals, and molecules of DNA that can be used to help us understand how natural living systems work. Those are probably the three big uses right now: the scientific market, the drug market, and the manufacturing market.
There are other people who are creating new markets. There are people who take DNA and don't use it as a genetic molecule for encoding functions inside living systems; instead, they turn it into an instruction molecule. DNA can be programmed to fold up into two-dimensional or three-dimensional patterns outside of a cell, so you can use it to build stuff, e.g., an inorganic computer where the DNA scaffolds are templates where the inorganic metals go to make the computer. In another application, George just demonstrated the use of DNA for archival data storage of books.
Baker: Protein design has huge promise, but is still in its infancy. What that means is that most of the designs we make will either not have the desired function at all or will have relatively low activities. We have to screen a lot before we get good ones.
We're making brand new things and we're not very good at it yet. How well we can make things and how fast we can learn is totally a function of how many designs we can make and how many genes we can get. By being able to test 10 or 100 times more designed proteins with high-throughput gene synthesis, the activities of the best ones would perform much better and, second, we would get a lot of feedback on what works and what doesn't.
Protein design is not a major industry, but if we could make things on a much larger scale, then it really could be. High-throughput gene synthesis is an enabling technology for that.
Baker: We've already designed influenza inhibitors that neutralize the virus. Those are in development as influenza therapeutics by a major pharmaceutical company. We have designed enzymes which catalyze a variety of reactions, which aren't catalyzed by naturally occurring enzymes.
There's a broad area of application for protein design. We're now trying to design protein therapeutics against a broad range of infectious disease and cancer cell targets. We're trying to make new materials—we just had a paper in Science on self-assembling proteins that will assemble into cages and other useful types of structures. We're designing new vaccines, pathways for carbon fixation, and receptors for small molecules. These are all areas where high-throughput gene synthesis can make a difference.
Church: Gen9 is the only company that I know of actually delivering diverse sets of large DNA constructs assembled from oligonucleotides chemically synthesized on chips. Gen9 is also unique in their ability to do error improvement with or without sequencing—they've got all of those forces driving the error rate down and the price down.
Baker: We do computer calculations and run Rosetta, which gives us many hundreds of different amino acid sequences that are predicted to fold up to have the property that we want. It's easy to read off what the DNA sequences should be and to design genes for those, but making them has been the limiting factor. That's what Gen9 lets us do really quickly. Gene synthesis companies have been around for a while, but you couldn't go and order 400 genes.
Endy: The essence of the technology had been demonstrated within academic laboratories—mainly by Joe Jacobson at MIT and George Church at Harvard. For Gen9, it was really a question of professionalizing the process around it, making it more reliable and able to be run in a repeatable way. From an abstract perspective, that's all we needed to do: get so good at running these processes that we could reliably communicate with people about what we were going to promise them and then deliver against those promises.
I don't mean to understate the technical feat. Actually pulling this off in the real world is crazy challenging and it took several years to get this to all come together. It's really a story of professionalization of a technology and unapologetic improvement and optimization of a manufacturing process.
Endy: Our collective responsibility is to conduct our work in a way that is safe for the people at the company, for our customers, for the public, and the environment. We must help lead the field of synthetic biology such that, to the extent we can impact this, our technology is not intentionally misapplied to cause harm. And to engage with anybody, including other companies and governmental agencies, who wants to work constructively on such challenges together to identify what outstanding issues there are and how they can be mitigated.
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The reason for my frustration is a particular mother whom I know who has been posting on FB about how they are tight on money and yada yada her whole pregnancy and not that she has just delivered her LO, she is already gulping down monster energy drinks while feeding her baby formula.
I don't get it? Why would one not even try when they don't have a lot of extra cash to spend?
Sorry for the rant- I just don't get it!


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Open education resources: Moving from sharing to adopting | Opensource.com
Open education resources: Moving from sharing to adopting
Educators have been sharing open educational resources (OERs) for over 12 years now. There are literally tens of thousands of them out there, many structured as collections of course materials known as open courseware (OCW), some structured as complete open courses, some structured as complete open textbooks, and many not really structured at all. The "sharing ball" is rolling. There are more materials that need to be shared, but the eventual sharing of these materials has now become inevitable.
What is anything but inevitable is the adoption of any of these open educational resources. As a thought experiment, pick your favorite institution you believe is committed to open education. Have they ever adopted an open education resource produced at another institution for in-class use? If they have an open courseware collection, can you find a single third-party OER in the collection? If even the institutions that claim to be committed to open educational resources aren't reusing them, who will?
While the mainstream of education will finally begin sharing OERs this decade, those leaders who think of themselves as being on the cutting edge of the open education movement need to start walking the walk / becoming living examples / modeling the desired behavior of adopting others' OERs.
If open education practitioners (both individuals and institutions) cannot move from large-scale sharing to large-scale adopting, the field is dead. I'm reminded of a scripture:
For what doth it profit a man if a gift is bestowed upon him, and he receive not the gift? Behold, he rejoices not in that which is given unto him, neither rejoices in him who is the giver of the gift.
A sustained program of giving becomes pretty pointless when it's clear that no one is willing to receive, regardless of how impressive the scale of would-be giving is. And if the givers don't play the role of receivers every now and then, the field risks a damning perception of arrogance whereby reusing OERs becomes something that only second-class programs do. Who will adopt / reuse then?
We need brave adoption leadership now just as badly as we needed brave sharing leadership ten years ago. Who will provide it?
This article was originally published by Dr. David Wiley at iterating toward openness and released under a CC by license. We have made slight changes for publication with permission from the author. If you would like to reprint the article, please use the original version and attribution.
7 Comments
"pick your favorite institution you believe is committed to open education." Okay: The Wikimedia Foundation "Have they ever adopted an open education resource produced at another institution for in-class use?" Sure, they accept contributions of OERs all the time; in a way they accept nothing but OERs for redistribution.
However, I have thus far been unable to convince them to adopt Moodle's GIFT format for self study quiz markup, which needs to be far more pervasive for utilization in order to match different levels of content -- or different sections of the same OER -- to learners' varied individual skills at any given point in time. I wonder if you were meaning to refer to http://microformats.org/wiki/gift with that scripture passage.
In any case, please email Foundation Director Sue Gardner, sgardner at wikimedia dot org and ask that GIFT be included in the Mediawiki Quiz extension. Thank you!
If the tens of thousands of OERs you reference were any good, they'd be adopted. That they aren't tells you something.
Anyone can put together something that suits their particular class and upload it to a big slushpile. And anyone does! What they generaly don't do is make their content relevant to other schools' classes. Why should someone adopt something for any reason other than it's the best for their class AND convenient for them?
"Who will adopt / reuse then?"
Developing countries. That's who the OER movement primarily benefits. Developed countries have no need for it. Advocates for this movement are like people who raise funds for the symphony orchestra. Nice cause, but not essential, and most people wouldn't miss it if it were gone (as evidenced by the low third-party adoption rate).
I am unsympathetic to complaints of high textbook prices as the raison d'etre for the OER movement. Get tuition prices in line and have full-time college faculty work a full 40 hour work week instead of calling 24 hrs/week full-time. That savings will pay for textbooks. It will even leave a slush fund to pay for all the ancillary class supplies many students need that cost far more than textbooks.
...Because I know a few great professors who would love to transfer to such a place. :)
I imagine such folk exist, but most of the academics I know (from community colleges to Ivy League) work far more than 40 hours/week, between teaching, research, grading, student guidance, grad student advising, committees, conferences, travel, and publishing.
My suspicion about the lack of adoption of OERs is that it's human nature to think you can do something better than what's already out there. Maybe the first step is adopting and mashing-up and reposting OERs? Many have licensing that allows it, from what I've seen.
I do suspect there is informal adoption that happens, too. A prof may use lots of the sources listed in an OER and save time in course prep, for example.
Dr. David Wiley has extensive experience with Open
Education. He is working with programs that are doing very well.
This is the time to try everything, use anything that might work.
All over the world we are in a mash-up culture now. Take any
Idea and adapt it to your needs. Roll your own!
Education has for far too long been in the hands of people that
are not trained in education. There needs to be an Open Source
Education Community, focused of the students.
Community, work together of perish!
Not sure if that was directed to me, but I'm not questioning Dr. Wiley's experience with Open Education. He seemed to be wondering why more people haven't adopted 3rd party OERs. I suggest it's because they're not very good. It can also because they're hard to find or take too much work to adopt to one's own class.
I have no reason to go to Connexions or wherever and spend hours-days-weeks-months or more stringing together chunks of modules when perfectly good textbooks are already written and available. I can adopt those to my needs far easier than I can third party OERs.


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DocHive saves journalists time spent on data extraction from PDFs
Journalist creates open source solution to extract data from PDFs
A group of journalists are announcing the launch of their breakthrough open source solution for the problem many writers and journalists have of how to take data in PDFs or images and easily convert it to a spreadsheet or other usable format.
Editor Charles Duncan Pardo and his team of reporters at the Raleigh Public Record are like many small newsrooms—they don't have the staff to do data entry for hundreds of pages of information, nor the budget to hire some unfortunate college student to do it for them. He says:
This is a problem we at the Record have been trying to overcome for more than two years. The story started with Wake County campaign finance returns. The returns are filed as paper, and staff at the Wake County Board of Elections scan them in and put the images online. The problem is, the only way to view the data is to look at it page by page, and the only way to analyze it is to go through by hand and enter the data into a spreadsheet one row at a time.
Duncan created DocHive with his brother, fulltime programmer Edward Duncan. It uses XML to break a page up into smaller sections, separating each into its own image file, then uses optical character recognition technology (OCR) to read the couple words or numbers and insert it into a text file.
DocHive will be officially released on February 28 at the annual Computer Assisted Reporting conference organized by Investigative Reporters & Editors and the National Institute for Computer-Assisted Reporting. The code will live on GitHub and the Record is setting up a Wiki on their server to share templates and for documentation. Their choice of which license to use has not yet been determined.
The technology clearly comes as great news to journalists and other writers across the country who will now have a way to easily and quickly convert data into structured information.
According to Tyler Dukes (managing editor at Reporter's Lab, a resource for journalists seeking technology solutions), although it's a common struggle for journalists, few others have tried to solve it. Neither Paul Bradshaw, a British journalist and author of "Scraping for Journalists," nor Pete Warden, developer and author of "O'Reilly's Data Source Handbook," had heard of a similar solution. He continues:
Public records provide a wealth of information reporters can use to hold the powerful accountable. But antiquated government and corporate bookkeeping can make dealing with these documents expensive, time-consuming and out of reach for many newsrooms.
By equipping reporters with the ability to automatically digitize these scanned paper records, DocHive could take hours of drudgery out of the early stages of document-driven investigative reporting and dramatically upgrade the watchdog capabilities of newsrooms large and small.
Duncan and his brother will present DocHive at the NICAR conference in Louisville, KY on March 1.
4 Comments
Couldn't you just use the open source WatchOCR, OpenOCR or even upload PDFs to Google Docs with OCR?
Sure, you could. You could also develop something that will be more integrated and more specialized to this particular task. That's the beauty of Free Software - there's choice, and there's the power to do things for yourself and for others.
It's evident here that the developers are thinking not just about their own use, but of the community of journalists who may need such a tool. I look forward to seeing what they've come up with.
You're too kind, ma'am. Thanks for writing this article and others like it. It really is all about empowering folks to do what they do best.


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Developers of DTC Genetic Testing Are...
Wall Street Decline Takes Its Toll...
As Immunotherapy Revolutionizes the Cancer Treatment...
LC-MS Gains Favor Due To the...
As the number of samples increases and smaller biobanks consolidate, accurate tracking, storage, and retrieval become vital issues. Many organizations still store and retrieve samples manually from liquid nitrogen (LN2) tanks or -20ºC or -80ºC standalone freezers, an approach that is fraught with difficulties.
The first issue is the maintenance of sample quality because degraded samples may compromise assay results. Storage temperature should remain stable to ensure sample integrity. However, the constant opening and closing of a manual door creates continuous temperature fluctuations and freeze-thaw cycles.
A door held open on a manual freezer for even a short period of time can result in a significant temperature rise. Constant frost buildup makes samples harder to locate and must eventually be removed, which further exposes stored items to temperature fluctuations. Additionally, air expands by approximately 50% when its temperature rises from -80ºC to 20ºC. This creates an air draft in an upright freezer, which accelerates more fluctuations.
Data gathered by Hamilton Storage Technologies shows that the temperature of samples taken from -80ºC storage to ambient conditions increases at an average of 21.5ºC per minute (Figure 1). Holding a manual freezer door open for more than one minute can raise the temperature to above -60ºC. This can happen countless times over the lifetime of a sample stored and retrieved manually. Accumulated temperature rises above this level are believed to damage the integrity of many types of biospecimens.
Another notable challenge is the staff size needed to run a manual biorepository. For instance, the Rutgers University Cell and DNA Repository utilizes around 100 technicians to perform biorepository services and store samples for a fully functioning biobank that consists of 45 LN2 tanks and 90 chest freezers. The labor costs of running a manual biobank are high, and as biobanks continue to grow in size, manual access becomes increasingly more complex and difficult to manage accurately.
Additionally, accessing samples in manual freezers can consume significant amounts of the staff's time. The Table shows the time required for each of the steps from storage to retrieval, comparing the use of a manual freezer to an automated storage system. Many manual biobanks encounter similar issues, according to assistant director Melissa Rawley-Payne from the CTSI Biorepository at the University of Florida. In some cases, she believes it could take hours for samples to be retrieved from freezers in some of the nonautomated tissue banks across the campus.
Sample security is another critical issue in any facility that is operating under regulatory controls, maintains potentially dangerous chemicals or infectious agents, or that maintains associated donor data with the samples.
In order to comply with various regulations, facilities must produce chain of custody reports and audit trails showing who had access to the samples and what they did with them. The lack of such security measures can even put the public at risk, as was the case in 2001 when anthrax was retrieved from an unsecured lab.
Martin Frey, Ph.D. ([email protected]), is senior product manager at Hamilton Storage Technologies.
Martin Frey, Ph.D. ([email protected]), is senior product manager at Hamilton Storage Technologies.
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text:
on May 10, 2013 - 8:16 PM
The recent homicide ruling in the death last November of burglary suspect Richard Metcalf Jr. at Erie County Medical Center has left his parents "emotionally spent," a family spokesman said.
"Again, they are devastated," attorney Thomas J. Casey said of the Lancaster residents. "They want the people who caused their son's death to be held accountable. They want the truth."
The Metcalfs – Richard Sr. and Jane – are not willing to publicly speak about the case, Casey said.
Richard Jr., 35, died Nov. 30 while in police custody at the hospital. He had been arrested in Depew three days earlier.
Depew police reportedly used a stun gun twice on Metcalf as he charged at officers with a heavy metal wrench the night he was taken into custody.
State police are investigating what happened to Metcalf, who suffered a heart attack in an ambulance as he was being taken to ECMC for mental testing.
According to a Depew police report, Metcalf was "acting strange" when he was arrested. Police confronted him after he allegedly broke into St. Joseph's Country Manor and Grove Catering in Depew. His unusual behavior led to reported scuffles with members of the Depew Police Department and the Erie County Sheriff's Office.
The case may ultimately end up before an Erie County grand jury.
Erie County Sheriff Tim Howard said he "felt compelled" to respond to questions of force.
"We determined, and remain confident, that our use of force was justified and proper, and that it did not cause the death of Mr. Metcalf," Howard wrote in an email.
"Following the medical examiner's report, we contacted the Erie County District Attorney's Office, and welcome an additional review, including the assistance of the New York State Police, since two different police agencies were involved. I remain certain that this review will find no fault with the conduct of our security staff."
Depew police officials could not be reached to comment.
Former Erie County District Attorney Frank Clark said one issue, among others, is whether the physical force to subdue Metcalf was justified.
"Normally, tasing is not considered deadly physical force. You also have some evidence of blunt force trauma," Clark said.
"There is testimony that he was difficult and had to be subdued, and now there is the wild card thrown in that this guy had a heart condition.
"The grand jury could determine if the physical force triggered other factors that triggered his death, and whether it occurred in Depew or the sheriff's office," Clark said.
At Metcalf's arraignment in Depew, the judge ordered a forensic examination after police reported he had been "acting strange" and behaving violently. His mug shots at the Erie County Holding Center show him bruised and cut on the face.
"He walked into the Holding Center Tuesday afternoon, and he was taken out a little more than 30 hours later face down on a stretcher. He was taken to Buffalo General Hospital, where he was treated and then transferred to ECMC because of the trauma," Casey said.
"On Friday afternoon, Nov. 30, he was declared brain-dead," Casey said.
Metcalf, who Casey said worked in the stockroom at Walmart in Depew, stood 6 feet tall and weighed about 200 pounds.
Casey said the corrected death certificate issued April 25 listed the manner of death as a "heart attack as a consequence of hypertension, stress, liver disease and blunt force injuries."
Casey in February filed a notice of claim against the Village of Depew and the village police department, as well as Erie County, the Erie County Sheriff's Office and Erie County Medical Center.
email: email@example.com


text:
Top Definition
From a foamy clip, a lollipop inserted into the ass. This lollipop may be sold in an auction to horny geeks or may be used in sexual play to feed to your partner.
Support the foamy cult, buy an asspop today!
She never knew it was an asspop I fed her.
She never knew it was an asspop I fed her.
po ravenwyck Април 5, 2006
Trending Now
Can you define these popular missing words?
noun - 1. the popping sound created when a man pulls his cock out of his lover's ass; 2. a lollipop that has been inside someone's ass, similar to a pussy pop
"Your sister is a freak! Instead of sticking that lollipop up her pussy, she stuck it up her ass. I loves me a tasty ass pop!"
po robin pisshole Јун 6, 2006
Someone who is extremely lazy and repulsive. Also, someone who has very poor hygiene and head lice. And a person that likes to administer enemas.
Ryan Klassen is an asspop. I don't know what his friends see in him.
po Ron Miller Септембар 16, 2003


text:
High Schools Gallery
Plano West tennis team's run ends in state semifinals
Photo: Ashley Landis/Special Contributor
Plano West's Josh Granberry reacts to a shot during a boys double match with partner Anshul Pandey at the UIL Class 5A team tennis state semifinal between Plano West and New Braunfels High School on Mon., Nov. 4, 2013 at the Mitchell Tennis Center at Texas A&M University in College Station, TX.
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Please post on my behalf:http://www.guardian.co.uk/culture/2011/dec/19/wedgwood-museum-selloff-court-ruling and: http://www.familyhistorian.info/museum/ Note the piece concerning John Cauldwell of Phones4u. He is proposing to buy the Museum lock stock and barrel in order to save it!! We await the outcome, as legalities have to be overcome... perhaps some good news to start 2012?? It's even being discussed at ministerial level in Government.
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