text:
As Immunotherapy Revolutionizes the Cancer Treatment...
Developers of DTC Genetic Testing Are...
Wall Street Decline Takes Its Toll...
Expanding Use of NGS Has Largely...
ADCs have to carry enough drug to kill cancer cells, get inside the target cell, and only then release the drug.
B-cell lymphoma has gotten plenty of attention from drug developers. Some spectacularly successful drugs, particularly mAbs, have improved its treatment and prognosis. Rituxan, arguably the biggest game-changer in non-Hodgkin B-cell lymphoma treatment, targets the CD20 antigen present on B cells. But a different antigen altogether, CD30, characterizes Hodgkin lymphoma (HL). HL has historically been considered curable with radiation and chemotherapy.
Why, then, is Seattle Genetics collaborating with Millennium Pharmaceuticals: The Takeda Oncology Company to develop brentuximab vedotin, an antibody drug conjugated (ADC) chemotherapeutic to treat HL? The market is relatively tiny compared to non-Hodgkin B-cell lymphoma, with an annual incidence of about 8,500 (as of 2009) in contrast to B-cell lymphomas, which generally occur in individuals older than 50, with an annual incidence of 65,980 (as of 2009). Additionally, patients diagnosed with HL during 2006–2010 had long-term survival expectations close to or exceeding 90% in all age groups up to age 45. Survival rates exceeded 80% and 70% in the 45–54 and 55–64 age groups, respectively.
But, Clay Siegall, M.D., Seattle Genetics' president and CEO, pointed out to GEN, "We have plenty of patients to treat, and HL isn't a cured disease." Seattle Genetics is also targeting T-cell lymphomas, a group of malignancies that also express the CD30 antigen. The company believes that ADCs have the potential to offer safer options.
Rationale for Using ADCs in HL
Despite high cure rates and low incidence, HL presents a unique opportunity as a target for ADC-based therapy. Hodgkin remains the most common malignancy in people between 10 and 30 years of age; the average age at which it occurs is about 28. This means that the majority of individuals who get HL are young, with potentially long lives ahead of them.
The disease has generally been treated with the chemotherapy regimen ABVD (adriamycin, bleomycin, vinblastine, dicarbazine) and, until recently, with radiation to treat refractory or relapsed disease. Young children were routinely treated with radiation delivered to multiple body sites to achieve remissions. These so-called cures, however, were achieved at considerable cost to some patients whose long-term survival was compromised by the development of other serious illnesses.
And apart from the need for better and safer treatment methods for younger patients, Dr. Siegall noted that "when we looked at HL and talked to experts in the disease, 25% of all HL patients are treatment-refractory or relapse, so we saw an unmet need."
In 2008, researchers at Stanford University reported that low-dose radiation for HL leaves children at a significant risk for second malignancies. And a study published in 2009 revealed that women who had been treated during childhood with radiation for HL were almost 40 times more likely than others to develop breast cancer. Also, HL patients treated with radiation have a substantially higher risk of stroke, according to a study published in 2009 in the Journal of the National Cancer Institute (JNCI).
In an editorial accompanying the JNCI report, the National Institute of Aging's Dan Longo, M.D., commented that the findings added to the already overwhelming evidence that using radiation therapy in HL was shortsighted. "Although treatments for this disease have included reduced doses of radiation since 1995, there is no evidence yet that this translates into fewer late effects for survivors."
By empowering antibodies by linking them to chemotherapeutic agents, Seattle Genetics and other companies hope they will provide a novel form of therapy for HL and improve treatments for other cancers. ADCs are considered attractive, safer alternatives to conventional chemotherapy because they combine the specificity of mAbs with the potency of cytotoxic molecules, delivering them directly to their intended targets and, theoretically, avoiding systemic toxicity.
Seattle Genetic's brentuximab vedotin combines an anti-CD30 antibody linked to its synthetic drug payload, monomethyl auristatin E, an antitubulin. Like other ADCs, the antibody/cytotoxin construct is designed to be stable in the bloodstream but to release the cytotoxic drug upon internalization into CD30-expressing tumor cells. Seattle Genetics notes that its technology allows stable linkage of the antibody to a chemotherapeutic agent. It has been licensed by several companies including Bayer Healthcare, CuraGen, and Progenics to develop new cancer therapies.
The CD30 antigen, according to Seattle Genetics, provides an attractive target for cancer therapy because it is expressed on Hodgkin lymphoma, several types of T-cell lymphomas, and other hematologic malignancies but has limited expression on normal tissues.
Seattle Genetics and Millennium reported in February that they have initiated a Phase I trial of brentuximab vedotin in combination with chemotherapy for the treatment of newly diagnosed HL patients. "We are on track to report top-line data from our pivotal brentuximab vedotin trial for Hodgkin lymphoma in the second half of 2010, positioning us for a planned New Drug Application submission in the first half of 2011," Dr. Siegall said.
Technology Shows Potential to Expand into Other Cancers
ADC technology also has the potential to extend the use of currently marketed antibodies. ImmunoGen says that its payload technology, which is used in the only armed antibody, Herceptin, has shown activity in patients whose cancer progressed on the same, unmodified antibody. TDM1 is a conjugate of the chemotherapy agent DM1 and the Herceptin antibody. DM1 belongs to the maytansine class of chemotherapies that targets microtubules.
Roche and Genentech reported results of a clinical trial of TDM1 in December 2009, showing that it shrank tumors in women with highly advanced Her-2 positive breast cancer. Women in the study had already been treated with an average of seven drugs for metastatic disease prior to receiving the ADC, including chemotherapy, Herceptin, and Tykerb (GlaxoSmithKline).
"Despite major advances in Her2-positive breast cancer, the disease may still progress after multiple treatments, to the point where there are no approved Her2-targeted medicines," Hal Baron, M.D., evp of global development and CMO at Roche, noted. "Results from this study are promising for women who need new treatment options, and we will discuss the next steps of the TDM1 development program with the FDA."
Following the Rituxan model, Seattle Genetics is focused on getting its first FDA approval for relapsed HL and for anaplastic large-cell lymphoma and then combining it with chemotherapy for first-line HL treatment. "Ultimately," Dr. Siegall commented, "in HL we have a great opportunity to bring the drug to the front line to get a higher percentage of patients with durable complete responses, lessen the amount of chemotherapy, and, maybe, get rid of the radiation therapy.
"Monoclonal antibodies are phenomenal drugs," Dr. Siegall said but added that empowered ADCs will provide the next generation of blockbuster antibodies.
Patricia F. Dimond, Ph.D., is a principal at BioInsight Consulting. Email: [email protected].
Patricia F. Dimond, Ph.D., is a principal at BioInsight Consulting. Email: [email protected].
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HOOVER, Ala. – SEC Media Days zaniness included South Carolina defensive end Jadeveon Clowney calling senior quarterbacks Tajh Boyd of Clemson and Aaron Murray of Georgia and former Arkansas quarterback Tyler Wilson "scared." Offering their Manning Passing Academy updates, Heisman Trophy winner Johnny Manziel said he "was absolutely not hung over" and Alabama quarterback A.J. McCarron said he tried unsuccessfully to wake Manziel in time for a meeting.
But the most sensible rant this week? A big easy: LSU head coach Les Miles on the unfair nature of SEC cross-division scheduling.
"I'd have to say there's a repeated scheduling advantage and disadvantage for certain teams in this conference based on tradition and traditional matchups," Miles said.
Miles didn't specifically say Alabama gets to play Tennessee every year while LSU has Florida as its permanent rival. But that's clearly what he meant.
This year LSU plays sure-to-be-ranked Florida and Georgia from the SEC East while Alabama plays lightweights Tennessee and Kentucky.
"We play Georgia and Florida for the seventh time this year," Miles said. "I'd have to say there's some other schools that have not played Georgia and Florida in the same year in my entire time (at LSU) or since 2000."
Nick Saban tried to counter. The Alabama head coach has won three of the last four national titles, but the last two have come with only two victories during the regular season against teams that finished ranked in the top 20.
"I understand where Les Miles is coming from," Saban said. "I coached at LSU."
Won a national championship in Baton Rouge, too.
Saban said scheduling is, by nature, unfair.
"There can never be an equal path to the championship," he said. "Unless everybody plays everybody, that's the only equal path to championship. Everybody doesn't play everybody in the NFL."
That's right, Nick. But that's partly because NFL non-division schedules are tweaked by two games with parity in mind, giving the best teams from the previous season the most difficult path the next year.
Which brings up an idea: Why not design SEC cross-division schedules with the best teams getting the toughest draws, and vice versa?
So instead of the current 6-1-1 format (six division games, one permanent rivalry non-division game and one rotating non-division game) the SEC Parity Schedule would include six division games and two non-division games tied to reverse order of finish within a given division.
The formula:
No. 1 SEC East vs. 1 and 2 SEC West
No. 2 SEC East vs. 1 and 3 SEC West
No. 3 SEC East vs. 2 and 4 SEC West
No. 4 SEC East vs. 3 and 4 SEC West
No. 5 SEC East vs. 5 and 6 SEC West
No. 6 SEC East vs. 5 and 7 SEC West
No. 7 SEC East vs. 6 and 7 SEC West
And the flip-side for SEC West teams.
How the SEC Parity model would work for non-division games in 2013 (2012 standings rank contrasted with actual non-division opponents):
SEC East
1. Georgia
Parity – 1. Alabama, 2. LSU
Actual – 2. LSU, 7. Auburn
2. Florida
Parity – 1. Alabama, 3. Texas A&M
Actual – 2. LSU, 6. Arkansas
3. South Carolina
Parity – 2. LSU, 4. Mississippi St.
Actual – 4. Mississippi St., 6. Arkansas
4. Vanderbilt
Parity – 3. Texas A&M, 4. Mississippi St.
Actual – 3. Texas A&M, 5. Ole Miss
5. Missouri
Parity – 5. Ole Miss, 6. Arkansas
Actual – 3. Texas A&M, 5. Ole Miss
6. Tennessee
Parity – 5. Ole Miss, 7. Auburn
Actual – 1. Alabama, 7. Auburn
7. Kentucky
Parity – 6. Arkansas, 7. Auburn
Actual – 1. Alabama, 4. Mississippi St.
SEC West
1. Alabama
Parity – 1. Georgia, 2. Florida
Actual – 6. Tennessee, 7. Kentucky
Parity – 1. Georgia, 3. South Carolina
Actual – 1. Georgia, 2. Florida
3. Texas A&M
Parity – 2. Florida, 4. Vanderbilt
Actual – 4. Vanderbilt, 5. Missouri
4. Mississippi St.
Parity – 3. South Carolina, 4. Vanderbilt
Actual – 3. South Carolina, 7. Kentucky
5. Ole Miss
Parity – 5. Missouri, 6. Tennessee
Actual – 4. Vanderbilt, 5. Missouri
6. Arkansas
Parity – 5. Missouri, 7. Kentucky
Actual - 2. Florida, 3. South Carolina
7. Auburn
Parity – 6. Tennessee, 7. Kentucky
Actual - 1. Georgia, 6. Tennessee
Guessing here that Les Miles and like-minded fair scheduling fans vote for an SEC Parity rule, and that Nick Saban votes against.
Follow Gene Sapakoff on Twitter @sapakoff.

subset: commoncrawl


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He was 56 and had battled pancreatic cancer since 2004.
"Apple has lost a visionary and creative genius, and the world has lost an amazing human being," the company said in a statement. "Those of us who have been fortunate enough to know and work with Steve have lost a dear friend and an inspiring mentor. Steve leaves behind a company that only he could have built, and his spirit will forever be the foundation of Apple."
In a separate statement, his family said, "Steve died peacefully today surrounded by his family. ... In his public life, Steve was known as a visionary; in his private life, he cherished his family. We are thankful to the many people who have shared their wishes and prayers during the last year of Steve's illness."
On Aug. 24, Jobs had announced his resignation as chief executive in an email to employees that was also made public.
In his message, he said he could "no longer meet my duties and expectations as Apple's CEO," and the company's reins were handed over to chief operating officer Tim Cook.
In many respects, the news did not come as a complete shock.
On Jan. 17, 2011, Jobs had told the staff that he would be temporarily stepping away from the day-to-day management of the computer company he co-founded 34 years before.
Yet so closely was Jobs associated with Apple that even when he left the firm for 11 years (starting in 1985, when his relationship with the board of directors reportedly had soured), or took temporary leave in 2004 (when he first began to deal with his health), Jobs was still thought of as the corporate face of Apple.
Chasing Butterflies"I was born in San Francisco, California, USA, planet Earth, February 24, 1955," Jobs told the Smithsonian's oral history department, in 1995. "School was pretty hard for me at the beginning. My mother taught me how to read before I got to school and so when I got there I really just wanted to do two things. I wanted to read books because I loved reading books and I wanted to go outside and chase butterflies."
The future salesman extraordinaire – who would also found the visionary motion-picture company Pixar – spent his childhood in northern California's South Bay area, a region later to become known as Silicon Valley.
A summer job at the Hewlett-Packard Company prior to attending Reed College in Oregon (for only six months) led to Jobs's meeting, in 1970, his future business partner: a computer engineer named Steve Wozniak.
While it was Wozniak who actually built the Apple I and II, it was Jobs who, according to a 1997 Time profile, "made the key decisions that shaped the company and the PC industry in its formative years: to name his computer after a fruit; to package it in a molded plastic case; to hire world-class p.r. and marketing firms; and, most incredibly, to drop everything to build the industry-incompatible but user-friendly Macintosh after visiting Xerox's Palo Alto Research Center and seeing its icons, its windows, its mouse."
The newsmagazine also credited Jobs with making consumers face the life choice of Mac or PC.
"Steve had these dream of being one of the great people that has companies and makes products that change the world," Wozniak, in 2008, told the Bloomberg News Service at the time it mistakenly published (and then, with an apology, quickly retracted) an obituary for Jobs. "One of the few people like the Shakespeares and Einsteins that get well known – he wanted to be in that group."
Alexandra Wyman / Getty
UnconventionalA vegetarian and a Buddhist who wouldn't let his three kids watch TV for fear that it might stifle their creativity, Jobs had a fortune estimated to be in excess of $5.5 billion. "Jobs is still Jobs. He still projects a manic self-confidence in public," Time further enthused, this time in 2007, when it again named him one of the world's 100 most influential people on planet Earth.
In his "signature jeans-and-black-turtleneck outfit," said Time, Jobs "still has his edge: prosperity hasn't robbed him of his disrespect for conventional wisdom, his spooky ability to see around corners, and his feral determination to make perfect products at all costs. All in all, success becomes him."
Married in 1991, Jobs is survived by his wife, Laurene, and their three children: son Reed, born 1991, and daughters Erin, 1995, and Eve, 1998. Jobs and a former partner, Bay Area painter Christiann Brennan, also had a daughter, journalist Lisa Brennan-Jobs, born in 1978.


text:
15 best U.S. high schools
POSTED: 10:12 AM PDT Apr 24, 2013 UPDATED: 10:16 AM PDT Apr 24, 2013
These high schools are tops when it comes to quality public education, according to U.S. News & World Report.
The views expressed are not those of this company or its affiliated companies. Please note by clicking on "Post" you acknowledge that you have read the Terms Of Service and the comment you are posting is in compliance with such terms.blog comments powered by Disqus


text:
a nickname for a vagina. It can sometimes be stinky if you are bad and hasty. It often refers to a kitten.
Baby, my tooter is stinky!
od uživatele Datruth 03. červenec 2012
Trending Now
Can you define these popular missing words?
Top Definition
A tube, usually a cut off part of a straw, used to snort speed or coke with.
Dude, opnly use one tooter, then we can scrape it when we're done with the sack
od uživatele Merc 03. únor 2004
A thinly shaped cylinder used to put any manner of powder into your nose form a flat surface.
I don't care if you roll up a twenty - get me a tooter!
od uživatele K-Gray 12. březen 2005
A cylindrical device used to snort powdered drugs. Also used to inhale the smoke from drugs
Pass the tooter, it's my turn
od uživatele My butt hurts from all the gay sex 04. únor 2006
A university employee that is tasked with leading students astray rather than 'Rounding them out intellectually'.
My tutor is a crazy weird dude. I mean wow, mine taught me everything I needed to know about cocaine abuse in a single 'tootorial'. He is one mother of a tooter.
od uživatele jonimethfan 07. říjen 2011
cute little person that farts cutely
hey tooter
will you be my tooter?
"oh man tell me about your date"
"man she's such a tooter"
will you be my tooter?
"oh man tell me about your date"
"man she's such a tooter"
od uživatele alec and liz 02. květen 2010
Young adult of the male gender that "Toots it and Boots it"
Jerry is a real tooter, last night he kicked a girl out of his house right after having sex with her.
od uživatele dablackplayer 20. září 2010


text: Many couples respond to criticism in predictable and less-than-productive ways. Each partner becomes immediately defensive, angry and accusatory. The pattern is primarily developed to avoid the pain of self-examination and to push away the partner in order to regain one's own comfort level. This all happens reflexively and habitually. Counseling teaches both partners in the relationship techniques to avoid being chronically defensive and distant with each other. These include:


text:
Top Definition
Getting fingered by the school football team
I'm gonna wheelsy you so hard!
He got wheelsied yesterday!
He got wheelsied yesterday!
di capnsweatpants 23 maggio 2014
Trending Now
Can you define these popular missing words?
A situation or state of mind in which things are getting out of control or quickly spiraling into chaos. Picture a bus or semi-trailer truck driving at high speeds with its wheels coming off.
Our executives are failing to communicate a consistent message in the midst of all this public criticism. Things are getting wheelsy around here!
di sojourner1212 29 gennaio 2011


text:
Celebrity grandparents
POSTED: 07:24 PM PDT Oct 02, 2011 UPDATED: 11:00 PM PDT Sep 08, 2016
With Grandparents Day on Sunday, click on to see which of your favorite celebrities are also grandparents.
The views expressed are not those of this company or its affiliated companies. Please note by clicking on "Post" you acknowledge that you have read the Terms Of Service and the comment you are posting is in compliance with such terms.blog comments powered by Disqus


text:
on May 11, 2013 - 11:24 PM
, updated May 11, 2013 at 11:46 PM
When the last two Swiss Chalet rotisserie chicken restaurants in the United States – one in Amherst, one in Depew – went dark on Feb. 28, 2010, Western New Yorkers who grew up with the chicken, fries and sauce at the center of family nights, first dates and happy birthdays did the only thing they could:
They got their passports ready, pointed their vehicles toward Canada and planned pilgrimages to the land where Swiss Chalet was born.
"Lots of Americans come once a week," said Robyn Hildebrand, manager of one of the Niagara Falls locations, a shiny standalone store on Montrose Road with a drive-thru. "Some come multiple times a week. They usually have a list with them, of friends, people they know, orders to bring back for people in the neighborhood."
The border guards were among the first to notice the trend, followed by the staff at the Swiss Chalet on Lundy's Lane in Niagara Falls, Ont.
"I have a couple that comes once a week, from Rochester, an hour and a half's drive," said manager Wayne Deline.
For the Western New Yorkers who worship at the Swiss Chalet altar, Facebook is the minaret, the platform most often used to call the faithful.
It goes like this: An Internet-capable fan of the Canadian chicken chain posts a photograph lovingly detailing the holy trinity: a quarter chicken, fresh-cut french fries and brick-red dipping sauce.
If they grew up around here, a certain part of the audience will feel a stirring, a hunger whose source they cannot always name, but with its roots in their childhood; a hunger amplified by the fact that since 2010, satisfaction has required international travel.
Today, Americans account for 5 to 10 percent of the volume at the two Niagara Falls, Ont., stores. If the Department of Homeland Security scanners at the border checkpoint sniffed for Swiss Chalet's signature dipping sauce, a lot more trunks would get popped. "A lot of people, they'll come over and order 20 large sauces," said kitchen manager Matt Stewart. "Lord knows how they get it back over the border, but they do."
Lord knows.
"A lady came over with those plastic gallon jugs – milk jugs? – and filled up 30 or 40 of them," said Deline. "She was going to auction them off at the church bazaar."
Bizarre is what the passion of the Swiss Chalet pilgrims is to nonbelievers, which is to say most people. Rotisserie chickens have proliferated in restaurants and grocery stores, satisfying most customers' pressing poultry needs. Cara Operations, the Canadian company that owns Swiss Chalets among its 700 restaurants, didn't turn out the lights for nothing.
When you ask the pilgrims to explain the pull, though, you end up talking about more than money. You end up talking about the pure childish joy of dunking fries in sauce.
Raised on Buffalo's West Side, in a family of six, Connie Berti was introduced to Swiss Chalet on Main Street, in the former Laube's Old Spain space. "Even in elementary school ... Swiss Chalet was affordable, it was reasonable, and you got a nice meal."
There was nothing comparable, she said. "You didn't eat much chicken out those days. Then they make fresh-cut french fries. Never been frozen. That's the other factor: a delicious french fry."
The sauce sealed the deal. "It wasn't something your aunt made, or your mother, or your grandmother," said Berti, who is Sicilian and knows her way around a sauce. "It was just different and explosive on your taste buds when you dipped chicken in it."
The most unusual thing "was that at the end of your meal, they would bring you a little bowl, with warm water and lemon in it, to wash up," she said. "Guess what? They still do that."
Berti and her husband, Bob, brought their children, and another generation of Swiss Chalet fans were imprinted on the sauce. When the last store closed in 2010, after "lots of tears and unhappiness," Berti said tongue-in-cheek, "I searched the Web to find if there was another one."
Which brought her to the border – four times in 2012, and once this year. Sometimes, in a pinch, she oven-roasts a chicken "with a little smoke flavor on it" or buys a ready-made rotisserie bird, and pulls a packet of Swiss Chalet dipping sauce powder from her emergency stash, to simmer her own. "We have that in a pinch," she said.
The packets are available at Canadian supermarkets such as No Frills for about $1 each, or at Redlinski's in Cheektowaga. "I give them away to other Swiss Chalet addicts," said Berti. "When I was ordering them online, I was very careful about who I gave them out to. Now I dole 'em out like candy."
To Canadians, Swiss Chalet's main appeal is the food. Freshness is the mantra. If a chicken hasn't been sold in 45 minutes after coming off the roaster, it's turned into chicken meat for soup and sandwiches. The fries, fresh cut and cooked twice for a superior crisp? Five minutes unsold and they go into the trash, said Stewart, the kitchen manager. "The head office comes in to make sure," he said. "Fresh is guaranteed."
Swiss Chalet had about two generations for the sauce to seep into the locals' DNA. That was enough.
"As somebody who considers [himself] a pop historian of Western New York and Buffalo, there was something very Buffalo about that place," said Steve Cichon, news director for WBEN 930. His family were regulars as he grew up in Orchard Park, and it was part of the "dating rotation" with Monica, now his wife of 12 years.
"It was one of those places you think of when the plane lands, and people ask, 'Where are you going to go first?' " Cichon said. "We all became ex-pats, in a way, when Swiss Chalet closed. It was part of the taste of Buffalo, for so many people, that was gone."
So Cichon's heart goes out to the hungry who holler every time he posts a photo to Facebook.
"People go crazy," he said. Needlessly, in many cases, he pointed out. "It's not that far away, if you have a passport or enhanced license," Cichon said. "It's 25 minutes from the [Peace] bridge. There is a border between us, but it's not that far away."
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text:
Top Definition
An evil tribe of emos who have nothing better to do then go on UrbanDictionary.com and give everything a Thumbs Down rating, no matter how good, correct, or just plane right the word is.
dude, I submitted this awesome deff to Urban Dictionary, and it got 100 Thumbs Downs! I dont see what is wrong with it! everyone can agree on it!
Its them damn Thumbs Down Trolls again!
Its them damn Thumbs Down Trolls again!
di The Mad Jester 20 luglio 2008
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text:
Top Definition
the most believable news show on T.V
i don't believe anything untill its on the daily show
от jesus 30 юни 2004
Trending Now
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The greatest television satire on American politics and the mass media.
The Daily Show is a very witty and informative show. Go buy the book!
от 0M3N 27 септември 2004
The CNN of the independent minded.
While the Daily Show only flirts with integrity, CNN doesn't even have the courage to introduce itself.
от Subaru 02 февруари 2004
a "fake" news show hosted by jon stewart thats very funny but too liberal definitely not as funny as the colbert report
person 1: did you see the daily show yesterday
person 2: yea it was funny
person 1: did you see the colbert report yesterday
person 2: yea it was funnier
person 2: yea it was funny
person 1: did you see the colbert report yesterday
person 2: yea it was funnier
от burgerking2 12 юли 2006
A show that used to be great. Jon Stewart was always funny, and it had Stephen Colbert as a field reporter. Then, Colbert left and The Daily Show got way too serious. Instead of clever written jokes, Stewart resorted to saying Bush is stupid a million different ways. The show is occasionally funny, just not as good as it used to be. Also, there are people who watch this to get their real news. If you watch it as a comedy program, that's fine(even though it isn't as funny anymore.) If you watch this show to get your news and opinions on things, you should be shot.
The Daily Show used to be great but now it is just average. The Colbert Report is much funnier, watch that.
от stevedawg13 04 август 2006
Known for its comedic genius, The Daily Show with Jon Stewart is actually the most watched "news" program by undecided voters
It's only a half-hour long, but it's hilarious as heck!
от RHS Student 10 октомври 2004
The last vestige of the "liberal media (truth)" that Republicans bitch about so much.
The Daily Show is the shit.
от Genesis 13 септември 2004


text:
Arby's Smokehouse Brisket Sandwich
Contact: , 308-697-3486;
The checkoff is working on details to support the new Arby's Smokehouse Brisket Sandwich. It features thinly sliced, naturally smoked beef brisket, melted smoked Gouda cheese, crispy onions, smoked BBQ sauce and mayo, served on a toasted specialty roll. Yum!
It is being introduced in all 3,400+ locations in 48 states. Tthe promotion runs Sept. 16 through Nov. 24, 2013.
The Beef Checkoff Program was established as part of the 1985 Farm Bill. The checkoff assesses $1 per head on the sale of live domestic and imported cattle, in addition to a comparable assessment on imported beef and beef products. States retain up to 50 cents on the dollar and forward the other 50 cents per head to the Cattlemen's Beef Promotion and Research Board, which administers the national checkoff program, subject to USDA approval.


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Contact us within 400 days of purchase to arrange a replacement or refund when things don't go as expected. We'll even cover the cost of return postage for you.
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Order two or more items and receive free regular delivery via Australia Post. Offer available Australia wide on all products.
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We believe in supporting the Australian economy. As an Australian business we will provide a Tax Invoice including GST with every purchase.


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Standard grass seeds can be purchased at any gardening shop, builder's hardware store, or large discount store. Some of these stores may also sell sod. If you want buffalo grass or other native grasses you will need to get out the phone book and call around.
Sod is typically purchased directly from a sod farm or sod supplier. Sod usually must be ordered about a week in advance and cannot be stored for a long time. Because it needs to be installed quickly, make sure your soil prep work is complete before installing sod.


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By virtue of their partnership with Stetson Athletics, the Coggin Automotive dealerships will have a comprehensive presence and brand association with all Hatter teams. This partnership will allow Coggin unique promotional opportunities and the chance to develop their business by connecting with Hatter fans before, during and after each Stetson athletics event.
The first of these unique opportunities is the Coggin Honda/Coggin Ford "Best Seat in the House" promotion. Hatters fans who visit the Coggin lot and test drive one of their automobiles will have a chance to be entered to win two premium seats and be recognized at an upcoming Stetson home football game.
Considering that Stetson's first game sold out, and that several more games could do the same before the season is complete, winning the Coggin "Best Seat in the House" will present fans with the opportunity to enjoy the game in a unique, yet comfortable and stylish, setting.
"We've already enjoyed several years of partnership with the Coggin dealerships, so we're thrilled to have them on board as our first official Hatter Partner," Stetson University Director of Athletics Jeff Altier said. "After the strong local support from the fans, it's nice to see the same kind of commitment and partnership from local businesses as well."
In addition to its "Best Seat in the House" promotion at football, Coggin will enjoy a pervasive presence at each of Stetson's home athletic sites, throughout the Stetson Athletics digital space at GoHatters.com, and frequent recognition throughout more than 150 radio broadcasts and internet webcasts of live Stetson sporting events via Hatter Vision.
To enter for the chance to win the Coggin "Best Seat in the House", Stetson fans should visit either Coggin Deland auto dealership, located at 2677 North Volusia Avenue, Orange City, Fla.
To purchase tickets to any Stetson Athletics event, fans should visit GoHatters.com/tix or call 386.738.HATS.
After a road game this weekend at Florida Tech, the Hatters will return to Spec Martin Memorial Stadium for their next home game on Saturday, September 21. Kickoff against Birmingham-Southern College is scheduled for 7 p.m. and fewer than 1,000 tickets remain available for the game.


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President Barack Obama on Friday talked about the Trayvon Martin verdict.
Rally for Trayvon Martin scheduled
The Coalition (People United To Take Back Our Community) will hold a Justice for Trayvon Martin rally from noon to 2 p.m. Saturday at the U.S. Customhouse steps at 200 E. Bay St.
The rally is in support of the Rev. Al Sharpton's pledge to hold rallies in 100 cities across the country to press for federal civil rights charges to be filed against George Zimmerman.
Scheduled to speak are state Rep. Wendell Gilliard, Marlon Kimpson, Dot Scott, Ed Bryant, Thaddeus John Bell, the Rev. Dr. Jimmy Gallant, James Johnson and Thomas Dixon.
For details, call James Johnson at 843-532-0787 or Thomas Dixon at 843-437-1949.
The Post and Courier asked people if they think his comments will help Americans understand and move on.
Here are some of their responses:
"I don't really care what Obama has to say about racially profiling and murdering teenagers. In 2011 Obama profiled and murdered a 16-year-old American citizen named Abdulrahman al-Awlaki. When asked about it, Robert Gibbs said if he didn't want to be killed he 'should have (had) a far more responsible father.' Can you imagine what would happen if a Republican said that about Trayvon Martin?
I'd rather read what someone like Ta-Nehisi Coates or Jelani Cobb has to say instead."
Jeremy McLellan, Charleston
"It is what I have been trying to articulate all week!"
Pat Jones, Charleston
"The president is very much enjoying this distraction from his own failings, and I imagine he'll milk it for all it is worth."
Jimmy Ryan, Isle of Palms
"I think his comments were certainly fueling a fire. ... His comments were narrow in their scope but yet broad in how he referred to the African-American community as whole. Bigger than any of this what truly upsets me is that the 'light' has been taken off of the fact that a young man was murdered and a family lost their son ... regardless of color, he was a young man and a son, a friend ... many people (of a variety of skin colors) are now using this boy's murder for their agenda and it is disgusting.
Renee Eubanks, Mount Pleasant
"As a black man, I agreed with what he said. He talked about things we have all experienced. At the same time, I think it's time for us to move on, start healing."
Robert Pinckney, Summerville


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on March 14, 2013 - 12:03 AM
, updated March 14, 2013 at 12:56 AM
WASHINGTON – Some 280 civilian employees at the Niagara Falls Air Reserve Station will be furloughed every Monday starting in late April, and the 914th Airlift Wing will be grounded on that day as "sequestration," the painful set of automatic budget cuts engineered by President Obama and Congress, takes effect.
Base officials announced the furloughs Wednesday, and these furloughs could be just the start. The furlough announcement covers employees of the Air Force Reserve unit at the base, but the Air National Guard unit, the 107th Airlift Wing, has not yet announced its budget-cutting plan.
"Should these furloughs take effect in late April, the plan is for the 914th Airlift Wing to be closed for business on Mondays through the fiscal year," said Col. Allan Swartzmiller, the unit's commander. "However, base security and emergency services will still be maintained."
The furloughs mean that the full-time employees at the 914th will lose 20 percent of their take-home pay through Sept. 30, when the 2013 federal fiscal year ends.
"We are doing everything in our power to avoid or minimize the effects of this administrative furlough on our employees as it breaks faith with those who have proven themselves both effective and efficient to our mission and have made our Air Force better," Swartzmiller said.
Base officials announced the furloughs at a town hall meeting in Niagara Falls on Wednesday attended by more than 300 people.
Still, some of the details of the cutbacks remain to be worked out.
Pentagon officials have not given base officials an exact date for the start of the furloughs. While the current target date is late April, "that could slip," said Sgt. Kevin Nichols, a spokesman for the 914th.
The Department of Defense has said it will have to furlough most of its civilian employees for 22 nonconsecutive days to comply with sequestration.
At the 914th, "the decision was to keep everyone on the same page" and simply shut down the unit's civilian operations on Mondays, Nichols said.
Things could change, Nichols added, if the 914th is deployed overseas – as it has been repeatedly over its history.
The civilian furloughs are the second big blow to strike the Niagara Falls base.
A $28.1 million simulator project has been put on hold because of sequestration. Base officials say the simulator – which will be used to train Air Force Reserve cargo plane pilots from throughout the Northeast – is key to the base's future.
Such cutbacks are occurring throughout the military because sequestration will reduce defense spending by 13 percent for the rest of the year, compared with 9 percent for most other federal programs.
Obama and Congress agreed to those across-the-board cuts, hoping that they would be so draconian that they would force compromise on a more planned and orderly deficit reduction plan.
But the president and lawmakers never even came close to a deal to replace the sequestration cuts, which started to take effect March 1.
email: email@example.com


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With nature coming into full bloom, it is an exhausting time for bees. That's why the worker bees, who are all female, by the way, live only about six weeks in the summer. They live between four and nine months in colder times of the year.
And there is no rest for the weary; honey bees never sleep.
This was news to me: Honey bees are not native to North America but were brought over from Europe in the 1600s. And that proved to be huge, given the fact that honeybees provide pollination to about 80 percent of fruit, veggie and seed crops in this country today.
Honey bees have more amazing stats.
They fly at a 15-mph clip.
Their wings stroke 11,400 times per minute, which accounts for the buzzing sound.
And, honeybees are the only insect that produce food for humans.
Which is why we're here today. A colleague asked for recipes of any kind that use honey in a noticeable way.
The "Food Lovers Companion" has a few sage words about honey for the kitchen. One, the darker the color, the stronger the flavor (in general). Two, it's important to know type of blossom. For example, a buckwheat honey will be a much stronger flavor than a orange blossom honey. Now, I have never seen buckwheat honey but I get the point. All honey is not the same.
Pat Jarvis of Mount Pleasant pointed to two sources for recipes.
She says the Savannah Bee Company, which has a store on King Street, has a good number of recipes on its website.
Check them out at www.savannahbee.com. (Honey Peach Pie caught my eye immediately).
Pat also likes the recipe for Honey Glazed Field Peas in the "Lee Bros. Southern Cookbook."
"I have used Sea Island Red Peas from Anson Mills for this, and the peas were delicious," she says.
I happen to have the cookbook in my office, so here goes:
Matt's Honey Glazed Field Peas
For 6 people
1 pound dried field peas (21/3 cups), picked over and rinsed
8 cups water
3/4 cup aromatic honey, such as palmetto, tupelo or cotton, divided for use
3/4 cup dry sherry
6 ounces country ham, cut into 1/2-inch dice
1 large yellow onion, trimmed, peeled and coarsely chopped
3 large garlic cloves, minced
1 tablespoon extra-virgin olive oil
1 teaspoon kosher salt
1 teaspoon freshly ground white pepper
Place the field peas and the water in a large saucepan and bring to a boil over high heat. Cover tightly (with aluminum foil if the pan doesn't have its own lid), reduce the heat to low and simmer gently until the peas are just tender, about 35 minutes. Drain, reserving the cooking liquid.
Preheat the oven to 325 degrees.
In a 3-quart enameled cast-iron pot or casserole, combine the peas, 1/2 cup of the honey, the sherry, ham, onion, garlic, olive oil, salt and pepper. Stir in 21/2 cups of the reserved pea-cooking liquid. Cover and bake for about 11/2 hours, or until the peas are tender and most of the liquid is absorbed. Uncover, drizzle the remaining 1/4 cup of honey on top, and bake until all of liquid has been absorbed and the peas are glazed, about 45 minutes. Serve hot.
Gin Bell of Charleston writes, "I've enclosed a recipe for chicken wings that uses a lot of honey. It's adapted from Bobby Deen's TV show where he cuts back on the calories of his mother's recipes."
Gin says they have taken them to several parties and "we never get to bring any home."
Bobby's Chicken Wings
3 pounds chicken wings
Salt and pepper to taste (see cook's note)
1/2 cup hot sauce
1/4 cup honey
Cook's note: The Bells also suggest substituting Kirkland (Costco) brand Organic No-Salt Seasoning or Dash for the salt and pepper.
Preheat oven to 450 degrees. Wash and clean wings and cut into pieces. Trim away visible fat.
Season wings with salt and pepper (or a no-salt blend, if desired). Place wings on a jelly roll pan and spray lightly with canola cooking spray. Bake for 25 minutes.
Meanwhile, mix the hot sauce and honey to make a sauce. Brush sauce over baked chicken wings. Return wings to oven and broil for 5 minutes.
The Greeks are well-known for their honeyed treats, and so I was not surprised to hear from Mary Larry of Charleston with recipes from the local community cookbook classic, "Popular Greek Recipes." (The cookbook will be available at the upcoming Greek Festival, May 10-12 at Holy Trinity Greek Orthodox Church.)
Despite its name, this cake is bound to be delicious any time of the year.
Lenten Honey Cake
15 servings
2 cups all-purpose flour
4 teaspoons baking powder
1/2 teaspoon salt
1 teaspoon cinnamon
1/2 cup sugar
1/2 cup honey
1 teaspoon vanilla extract
1 cup pineapple or orange juice or water
1 cup chopped nuts
1 (10-ounce) package dates, chopped
1/2 cup grated coconut, optional
1 cup raisins
Combine flour, baking powder, salt, cinnamon and sugar. Add honey, vanilla, juice or water, nuts, dates, coconut and raisins. Mix well. Pour batter into a well-floured 10-inch baking pan. Bake at 350 degrees for 45 minutes.
Who's got the recipe?
With a greater variety of seasonal fruits and vegetables becoming available, a colleague asked for good and/or creative recipes for making smoothies.
A West Ashley reader requests recipes for grits casseroles.
Looking for a recipe or have one to share? Email firstname.lastname@example.com or call Food and Features Editor Teresa Taylor at 937-4886.


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City police officers swept through a hallway at Salem High School with guns drawn Thursday - all part of an active shooter training exercise to prepare them if the real deal occurs.
"I think it's the most important training we're going to do," Salem Police Chief J.T. Panezott said.
The guns were fake, no training bullets were used and there was no real intruder except for the occasional teacher who crossed into the cordoned-off area where officers practiced their moves.
Article Photos
Lt. David Casto, left, and Ptl. Richard Miller await their turn as Ptl. Brad Davis begins his solo sweep of a hallway at Salem High School during an active shooter training exercise. Davis works closely with the schools as the department's juvenile officer. (Salem News photo by Mary Ann Greier)
According to Panezott, the necessity for this type of training is all too real. The stories flash across the television and cover the printed page all the time telling of the latest school shooting, violent workplace event or movie theatre tragedy.
Boardman Police Sgt. Michael Hughes said he's "teaching officers what to do in such a situation from the beginning to the end."
Hughes has been doing this type of training since 2000 and has been training officers the past four years from other departments in both Mahoning and Columbiana counties. He said the lesson he wants officers to take away from the training is "the essence of getting there and stopping the threat as quick as possible."
Hughes and Panezott worked together for at least 10 years in the Drug Enforcement Administration and Panezott said they're lucky that he came down to train the officers. There was no cost for the training.
"They've got to know what they're doing immediately. We have to have a plan," Panezott said. "We have to know what we're doing."
Even if nothing ever happens at Salem High School, he said "they're going to use this every day."
The police department routinely responds to calls of active alarms, open doors or burglaries in progress, requiring them to search a premises without knowing what they may find inside.
Sgt. Danny Green said the training was long overdue and Sgt. Karl Toy said "it's one of the best trainings we've had. It gives us more confidence in our everyday job."
Another officer, Ptl. Richard Miller, said the training gets everybody on the same page.
The training was done in two sessions to give all officers the opportunity to attend.
Ptl. Brad Davis serves as the juvenile officer for the department and works a lot with the school district's administrators, teachers and students. He said the school officials were very excited for the police to train in the building.
Davis and Ptl. Craig Crider conducted some training with school district employees last spring on what they can actively do if there's an intruder or some other type of emergency in their building.
The district itself has been working on measures to improve security, also, with both equipment and additions to the policy already in place.


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#119 to #5 - ohgodwaitimatheist (05/08/2013) [-]
I play with almost any deck I manage to get the grap of the plays.
Virtually, of course.
Virtually, of course.
#47 to #5 - RosarioVampire (05/07/2013) [-]
motha ****** naturias
#54 to #53 - RosarioVampire (05/07/2013) [-]
bamboo shoot and fruit flys, or mosquito beans combo.
#65 to #61 - RosarioVampire (05/07/2013) [-]
field swarming shuts down naturias though :/ a friend of mine uses an incomplete black wing deck and its difficult. another friend uses an almost complete x sabers deck and i just get ****** up and down the street.
#67 to #66 - RosarioVampire (05/07/2013) [-]
i think six sams are broken as ****. :/ but most people say that about bamboo shoot too lol
#71 to #68 - RosarioVampire (05/07/2013) [-]
i have not seen any of the recent deck types. i finished my deck and bought a ghost rare black rose and said im done with buying yugioh cards. lol
#42 to #5 - huskycreeper (05/07/2013) [-]
Working on a morphtronic swarm deck, i just need some more machines.
#58 to #55 - huskycreeper (05/07/2013) [-]
Oh, well if you build the deck where they are always switching battle positions and always gaining more and more attack (like 4500 each turn) they can get pretty scary.
#76 to #60 - huskycreeper (05/07/2013) [-]
Whats a level 2 judge? but yeah i have a friend that helps with the rules and such, he knows like everything by heart.
#83 to #81 - huskycreeper (05/07/2013) [-]
Oh...thats cool, how often do you come across a guy and you just have to tell him "no"?
#95 to #92 - huskycreeper (05/08/2013) [-]
Oh geez.
#38 to #5 - shinycharizard (05/07/2013) [-]
Evilswarms, Madolche, and Constellar.
#86 to #63 - shinycharizard (05/07/2013) [-]
Yeah. Madolches swarm like crazy, and if you start off with Ultimate offering and Magileine, you can get crazy in like 1 turn.
Evilswarms are good against the meta because of Ophion's no special summoning effect, so that's a good advantage against Prophecy, mermail, E-dragons (unless they Blaster destroy Ophion).
Constellars are just good to troll with because no one knows how to play against them, but the major downside is that they lose hand advantage very easily.
Evilswarms are good against the meta because of Ophion's no special summoning effect, so that's a good advantage against Prophecy, mermail, E-dragons (unless they Blaster destroy Ophion).
Constellars are just good to troll with because no one knows how to play against them, but the major downside is that they lose hand advantage very easily.
#91 to #86 - wilburn (05/07/2013) [-]
well the constellaers are easy for the deck i most often run, hazy fire kings, i just force on the hazy of it, since not a Single hazy monster can be targeted by card effects, and if i get basilcock on the field with 5 xyzs, oh its over, cant be targetd by effs, cant be destoryed by effs and 3500 atk, plus a once per turn banish xP its over for constellers lol
#29 to #5 - barbwirepain (05/07/2013) [-]
i play, but i mostly collect
#28 to #5 - badhatharry (05/07/2013) [-]
Yeah, playing Six Sams at the moment. The meta (e-dragons, spellbooks and stuff) is just getting "OTK or lose" and it's pretty **** now.
#163 to #56 - badhatharry (05/08/2013) [-]
And the new MechaBeastPhantom XYZ that they use is coming out in the new booster. It looks like an expensive deck, but I still think it'll see a lot of play just because of how OP it is
#167 to #164 - badhatharry (05/08/2013) [-]
Yeah Darcosak (or however you spell it) is a Secret and I think Big Eye is too. The big E-Drags are all Rare and the young ones are Common, but having to play 3 of all the big ones and some little ones makes it look like they'll shoot up in price.
#30 to #19 - redsvenasuar (05/07/2013) [-]
Any tips on a photon deck?
#130 to #57 - redsvenasuar (05/08/2013) [-]
I'm going with a three gepd, knight and wizard building. Though still not sure if I should make if a pure photon/galaxy deck


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Thursday, June 27, 2013
Each week, the Moultrie News and Mount Pleasant Recreation Department will feature two local track and field athletes participating in the department.
Luke Pauldine, 12, participates in the javelin throw, 1500-meter and 3000-meter runs with the Mount Pleasant Track Club. Peyton Moore, 9, participated in the javelin and shot put events with the club.
Peyton passed away June 4, after he completed the questionnaire and before the time of publication. His family requested this be published in remembrance of his life and his love for track, as well as in recognition of Luke.
Question: If you could be anyone for a day, who would you be?
Luke Pauldine: Si Robertson, from Duck Dynasty.
Peyton Moore: Usain Bolt.
Q: What is your favorite Mount Pleasant restaurant?
LP: PF Chang's.
PM: Five Guys.
Q: What is the best moment in your athletic career?
LP: Being a part of the Mount Pleasant Cross Country bantam boys team when we won third place in the nation at the 2010 USATF Junior Olympic Nationals.
PM: Going to USATF Nationals for javelin.
Q: What is the best advice you have gotten from a coach?
LP: "Surge the curves," from coach Tami Dennis.
PM: It's hard, but it's fair.
Q: What do you look forward to the most about being an adult?
LP: Being able to do what I want, when I want to.
PM: Being able to run anytime I want to.
Q: What do you think are the most difficult and most fun aspects of track?
LP: The most difficult is running in the heat. The most fun is competing at track meets.
PM: The most difficult is the running intervals and the most fun is the part when I get to practice javelin and shot put.
Q: What is your movie and TV show?
LP: Movie: "Madea." TV: "Duck Dynasty."
PM: My favorite TV show is "E:60" and my favorite movie is "42" (The Jackie Robinson Story).
Q: If you could have dinner with any three people who would you choose?
LP: Si Robertson, Tyler Perry (as Madea) and Robin Williams.
PM: Usain Bolt, Ryan Hall and Paul Pierce.
Twitter: @MoultrieNews
© 2016 Moultrie News an Evening Post Industries company. All Rights Reserved.
Registration on or use of this site constitutes acceptance of our Terms of Service, Privacy Policy and Parental Consent Form.


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Today, July 31, is the feast of St. Ignatius Loyola, founder of the Society of Jesus. This is an appropriate day to write about the contributions of one of his sons, whose name is known by so few, but to whom the Catholics of New York owe so much: Father Anthony Kohlmann, S.J., the first vicar general of the Diocese of New York.
In 1808, Pope Pius VII created four new dioceses in the United States. One of them was New York. The pope named a Dominican friar, Father Luke Concannon, as the first bishop. The new bishop made plans to sail here from Naples, but Napoleon got in his way by placing an embargo on American ships. Realizing that he wasn't going to get to his new diocese anytime soon, Bishop Concannon wrote to the pope and asked for a vicar general to be appointed in the meantime. The pope named a German Jesuit, Anthony Kohlmann, to the position while the bishop tried unsuccessfully to set sail. Bishop Concannon died in Naples in 1810 and Father Kohlmann went on serving as vicar general until 1814.
At the time of Kohlmann's arrival, there was just one church for New York's 14,000 Catholics, St. Peter's. The pastor there was ill and shorthanded; the Catholics were, shall we say, a tad lukewarm in their practice of the faith. The energetic Jesuit soon could report that Mass was being celebrated in three languages, religious education classes were thriving, and the Catholics were outgrowing St. Peter's. It was a time for a second church and what a church it would be: the first St. Patrick's Cathedral. It was built on the site of a cemetery, well north of the northern border of New York City, Canal Street. Many Catholics complained that the site was too far out of town, but Kohlmann apparently understand that the city was growing and had only one way to go: north. This was a lesson a future ordinary of New York, Archbishop John Hughes would learn, too.
So we owe what is now properly called the Basilica of St. Patrick's Old Cathedral to a Jesuit. But we owe him more. Good Jesuit that he was, Father Kohlmann and his companions established a college near the first cathedral. However, the need for additional space led to the purchase of a site four miles north of New York, near Columbia University's Elgin Gardens. The Jesuit college moved up and into a mansion that already stood there. However, the Maryland Province of the Jesuits ordered this college to be closed so that the Jesuits could concentrate on another college they ran, the one in Georgetown. And what happened to the property? It became of the site of the current St. Patrick's Cathedral on Fifth Avenue.
Today, as we honor the founder of the Jesuits, we New Yorkers should give thanks especially for Father Anthony Kohlmann, who built the church of New York in mortar and practice.
Thanks to Thomas Young, author of a marvelous history of St. Patrick's Cathedral, New World Rising (Something More Publications 2006), for the story of Anthony Kohlman, S.J.


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Top Definition
The act of extreme drunken shoulder crying. Emofucking is NOT sex. The participants are usually either dating or just quite fond of each other, and more often than not of the opposite sex. In extreme cases, emofucking can be done while sober.
verb- "Rachel and Corey went into the bedroom with a Bright Eyes album and came out half an hour later with their eyes all puffy. You totally know they just emofucked."
noun- "Goddamn that was a good emofuck! My sweater sleeve is wet clear through. I need a cigarette."
noun- "Goddamn that was a good emofuck! My sweater sleeve is wet clear through. I need a cigarette."
viết bởi someonebored 26 Tháng năm, 2007
Trending Now
Can you define these popular missing words?
A derogatory term for an someone who some one who is considered to be "Emo". Generally used to express hatred towardsthem for being such fucking pussies and crying like fucking dickholes.
Bob: JIM IS SUCH AN EMOFUCK, FUCKING PUUSSY ASSHOLE BITCH!
Fred: i totally agree emo is FUCKING GAY.
Fred: i totally agree emo is FUCKING GAY.
viết bởi poposhoot 18 Tháng tư, 2005
Whiny, puny dudes who have worn tight women's jeans for so long that their testicles never dropped. They are constantly shoving their thin girl hands in their pockets which further complicates their testicular problems. As a result of this behavior emo fucks inevitably grow up to become adult teenagers who sit in the dark and listen to shitty,lispy songs about candles,dead dandelions,and unrequieted puppy love. They seldom make eye contact partly due to the greasy, dandruff laden, bangs that hang over their eyes and partly due to their lack of masculinity and/or courage. They love to call everything gay even though they would be gay if they could only achieve an erection in those cute jeans. In summary, emo fucks are weak poeple who need to hide in numbers. They identify with crappy faggy music and always try to be in love so they can get their heart broken and gain emo cred with their defeatist self loathing lackeys. I plan to run for president in '08 on the emo fuck holocaust ticket. If i win, we will have sweater burnings in the streets. We will provide guns and bullets to all emo fucks who want to kill themselves, and eventually we will reach the final solution: we will hold a huge free vegan buffet, but unbeknownst to the emo fucks... the food will have egg and cheese in it!
"Fear not the wrath of the emo fuck, for he is sensitive and quite fun to provoke."
viết bởi conorcrybaby 17 Tháng sáu, 2005
A Emo Fuck is a utter waste of space that normally sits on their own and contemplates life and what it would be like to die. In between wrist cutting sessions Emo Fucks like to cry over music. The most common dress code of a dirty Emo fuck is tight gay clothes and stripy jumpers. If a Emo Fuck is lucky to get threw life to the point of leaving school their choice of career is commonly a Hairdresser.
A Emo fuck could be a member of the Band Green day.
viết bởi Ross Macfarlane 06 Tháng bảy, 2006
normally a gay girl (or boy) who obsesses over dinosaurs, polka dots, and guns to there head.if you try to talk with them they normally look down and cover there eyes with their greasy black hair.
they cut there wrists as much as they cut there hair
they cut there wrists as much as they cut there hair
"hey you stupid emo fuck- look at me when i talk to you!"
viết bởi monefa 09 Tháng ba, 2005
stupid, ignorant, whiney wastes of human life. they sit in their corner with their friends, cutting their wrists and listening to fall out boy. emo fucks are mostly identified with their gay, shitty, and musically inept bands (such as hawthorne heights, senses fail, and underoath.) these emo creatures should all be drug out into the streets and shot simultaneously.
"My mom and dad hate me! Everyone hates me!"
In reality, this emo fuck is an only child and very popular at school, therefor getting excessive amounts of attention.
In reality, this emo fuck is an only child and very popular at school, therefor getting excessive amounts of attention.
viết bởi touch me im sick 08 Tháng mười, 2005


text:
Systemwide Events Calendar
Mobile Vet CenterDecember 19, 9:00am - 3:00pm
Leeward Campus, Flag Pole Parking Area
The Honolulu West O'ahu Mobile Veterans' Center will be on campus to provide information regarding VA benefits as well as other support for service members and families.
Ticket Information
Event Sponsor
Admissions and Records Office Veterans Affairs, Leeward Campus
More Information
455-0644, http://www.leeward.hawaii.edu/military
|Wednesday, December 19
|Mobile Vet Center
Leeward Campus, Flag Pole Parking Area
- Highlighted dates have scheduled events.
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Name of a member of the gang in the The Warriors a 1979 film. He is the muscle of the group, cocky and arrogant but a strong soldier and a great asset to the gang.
"yo man, you see Ajax?"
"No man what happened?"
"man he destroyed those pussy fucks."
"No man what happened?"
"man he destroyed those pussy fucks."
লিখেছেন- J Higgins 4 de জুন de 2006
Trending Now
Can you define these popular missing words?
Top Definition
Asynchronous Javascript And XML.
google maps uses ajax to pass data.
লিখেছেন- centreville nate 5 de মে de 2005
A football club named after a Greek mytholigical hero, based in Amsterdam Holland
Ajax "was" the best team in the world untill it sold all it's better players to barcalona :(
লিখেছেন- eejit 25 de জুন de 2004
A town in southern Durham Region, Ontario, sandwiched between Pickering and Whitby.
Pickering Villiage is part of Ajax.
লিখেছেন- mass 11 de এপ্রিল de 2005
A town in southern ontario in between the dirty O and Scar City
-where are you from, then?
-ajaaaaax...... (with a mad head shake)
-right on
-ajaaaaax...... (with a mad head shake)
-right on
লিখেছেন- burgiller 27 de ফেব্রুয়ারি de 2005
An industrial-strength cleaner sold by the company Colgative Palmolive, usually in powder form.
The fact that it took so long for someone to identify Ajax as a popular cleaner says a lot about the personal hygiene of Ajax soccer fans.
লিখেছেন- sukebe 21 de নভেম্বার de 2006
Ajax are a very successful Dutch Football team. They play at the Amsterdam Arena and have won many cups in their time.
"You wanna come see Ajax VS PSV Eindhoven tonight?"
লিখেছেন- Andy 20 de সেপ্টেমবার de 2003


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Shop Perry Ellis Discounted Clothing for Men
Premium menswear at prices your wallet will love. Shop the Perry Ellis Clothing Sale for men for stylish and comfortable men's apparel at discounted prices. Find your favorite Perry Ellis men's dress shirts, dress pants, casual pants and suits on sale. Save from 30% to 70% off sale styles.


text: This image stresses the amatory conclusion of the play. Ringold was type-cast as Romeo and Henry V. He toured the United States (where women fought over him) from 1875,and he made a great impression. Note the casting of a French actress as the princess. Courtesy N. Y. Public Library for the Performing Arts, Billy Rose Theatre Collection at .http://www.nypl.org/research/lpa/the/the.html


text:
Subtitle 18 BOARD OF CERTIFIED INTERIOR DESIGNERS
09.18.01 Fees
Authority: Business
Regulation Article,§§2-106, 2-106.1 and 2-106.2; Business Occupations and Professions Article, §§15-101, 15-208, 15-209, 15-311,
15-312, and 15-314; Annotated Code of Maryland
Notice of Proposed Action
The Board of Certified Interior Designers proposes to amend Regulation
.03 under COMAR 09.18.01 Fees. This action was considered by the Board at a public meeting held on April 22, 2013,
notice of which was published in 40:7 Md. R. 683 (April 5, 2013), pursuant to State Government Article, §10-506(c), Annotated Code
of Maryland.
Statement of Purpose
The purpose of this action is to increase certificate fees previously set by the Board in 2003 and then decreased in 2007.
Pursuant to the authority set forth in Business Regulation Article, §§2-106, 2-106.1, and 2-106.2, Annotated Code of Maryland,
the Maryland design boards, including the Board of Certified Interior Designers, may set various fees, including a certificate
fee, in order to cover the actual documented direct and indirect costs of fulfilling their statutory and regulatory duties. The
law provides that the Secretary must calculate these costs on an annual basis and provide them to the design boards for the purposes
of fee-setting. Based on the current levels of revenues and expenses, as certified to the design boards by the Department, it has
become evident to the design boards that an increase in license fees is necessary in order for the boards to strive to meet their
statutory obligations. The need for increase in fees is a result of a number of factors, including, but not limited to, increase
in personnel costs, as well as in fixed and indirect costs. The statute governing the design boards special fund limits a fee
increase to 12.5 percent annually. As a result, the design boards, both individually and as members of the design boards special
fund cluster, decided to uniformly increase their applicable license/certificate fees. Therefore, the license/certificate fee for
each Board is being raised by 12.5 percent.
Comparison to Federal Standards
There is no corresponding federal standard to this proposed action.
Estimate of Economic Impact
I. Summary of Economic Impact. There are currently 330 certified interior designers. Due to staggered renewals, 165 certificate
holders are expected to renew their certificates annually. In addition, an average of 25 individuals become certified every year.
Based on the assumption that these numbers remain constant, the State Occupational and Professional Design Boards Fund will receive
additional revenues totaling $1,615.
III. Assumptions. (Identified by Impact Letter and Number from Section II.)
A. Assuming 165, or 50 percent of current licensees, renew
their licenses in the first year, and 25 individuals receive new
certificates, revenues totaling $1,615 (190 x $8.50) will be
received by the Fund.
D. Applicants for new certificates and current certificate
holders are presently paying $68 for a 2-year certificate. The
proposed amendment will raise the fee to $76.50, an increase of
Economic Impact on Small Businesses
The proposed action has minimal or no economic impact on small
Impact on Individuals with Disabilities
The proposed action has no impact on individuals with disabilities.
Opportunity for Public Comment
Comments may be sent to Pamela J. Edwards, Executive Director,
Professional Licensing Boards, 500 N. Calvert Street, Room 308,
Baltimore, MD 21202, or call 410-230-6262, or email to email@example.com,
or fax to 410-333-0021. Comments will be accepted through October
28, 2013. A public hearing will be held October 28, 2013, 2:30
p.m., at 500 N. Calvert Street, Third Floor Conference Room,
Baltimore, MD 21202, to hear comments from the public concerning
the license fee increase.
Open Meeting
Final action on the proposal will be considered by the Board of
Certified Interior Designers during a public meeting to be held on
January 27, 2014, at 2 p.m., at 500 N. Calvert Street, Third Floor
Conference Room, Baltimore, MD 21202.
.03 Fees and Costs.
A. The Secretary and the design boards have agreed to average
their direct and indirect costs, based on the calculation of costs
performed by the Secretary in consultation with the design boards.
Based on these calculations, the Board sets the following fees:
(1) Certificate fee [$68;] $76.50;
(2)(3) (text unchanged)
B. (text unchanged)
Acting Chair
State Board of Certified Interior Designers
Return to the DLLR Services home page
Questions or comments regarding the Department of Labor, Licensing and Regulation may be directed to
Questions or comments regarding the DLLR website may be directed to email@example.com.
Updated September 23, 2013


text:
The 1854 founders of this city named it after the Omaha Native American tribe - Omaha means "those who go against the current." The town became a mid-19th century central stopping point for Greek, Irish, Italian, German, Scot, Mexican, Polish, African-American, Czech, and Scandinavian pioneers heading west--and they all left their enduring mark.
Kick back at the annual Omaha Blues, Jazz, and Gospel Festival. Or, check out the Indie rock scene at The Waiting Room Lounge. Get some cold beer and live jazz at Mr. Toad's Pub. Perhaps you'd enjoy the Scottish legacy Strathdon Caledonia Pipe Band. Have a broiled steak at Johnny's Cafe, Omaha's original steakhouse - it started in 1922 as a 10-seat saloon. Or, try trout almondine, fresh Parisian bread, and Burgundy wine at La Buvette brick-walled bistro and European grocery in the historic Old Market District.
Stroll cobblestone streets and browse art galleries in the artfully renovated produce warehouses of Old Market. You may pass street musicians and horse-drawn carriages. Make your way to the Hot Shops Art Center, a warehouse turned studio where 80 artists apply heat to ordinary objects and turn them into artwork. Discover the world's largest indoor desert and vast indoor rain forest at the Henry Doorly Zoo. Or, just take a walk in the Lauritzen Botanical Gardens, overlooking the Missouri River Valley.


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KOCO Eyewitness News 5's Anita Blanton talks to Gabriel Solis. He and his wife were arrested in October 2010 on suspicion of severely beating a child that was left in their care.
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|By Business Wire
Article Rating:
|April 14, 2014 03:00 AM EDT
Toshiba America Medical Systems, Inc. received approval to operate (ATO) with the U.S. Air Force, making Toshiba the only current manufacturer to have a fully certified CT system for use on the Air Force Network.
By achieving ATO status, Toshiba met the Department of Defense's stringent guidelines of ensuring protection of Patient Health Information (PHI) and guarding against malware, viruses and malicious attacks. To meet these requirements, Toshiba enhanced its CT platform to include Microsoft Windows 7 and application whitelisting software to proactively identify and prevent viruses and malicious solicitations.
"Toshiba provides the industry with product solutions that fit into any customer's business needs, including the rigorous cybersecurity requirements of the U.S. Department of Defense," said Satrajit Misra, senior director, CT Business Unit, Toshiba. "This breakthrough has opened doors to the commercial industry to offer customers access to the same level of security as the U.S. Air Force."
About Toshiba America Medical Systems, Inc.
With headquarters in Tustin, Calif., Toshiba America Medical Systems (TAMS) markets, sells, distributes and services radiology and cardiovascular systems, including CT, MR, ultrasound, X-ray and cardiovascular equipment, and coordinates clinical diagnostic imaging research for all modalities in the United States. For more information, visit the TAMS website at www.medical.toshiba.com.
About Toshiba Medical Systems Corporation
Toshiba Medical Systems Corporation is a leading worldwide provider of medical diagnostic imaging systems and comprehensive medical solutions, such as CT, X-ray and vascular, ultrasound, nuclear medicine and MRI systems, as well as information systems for medical institutions. Toshiba Medical Systems Corporation has been providing medical products for over 80 years. Toshiba Medical Systems Corporation is a wholly owned subsidiary of Toshiba. Visit Toshiba Medical Systems Corporation's website at www.toshibamedicalsystems.com.
About Toshiba
Toshiba is a world-leading diversified manufacturer, solutions provider and marketer of advanced electronic and electrical products and systems. Toshiba Group brings innovation and imagination to a wide range of businesses: digital products, including LCD TVs, notebook PCs, retail solutions and MFPs; electronic devices, including semiconductors, storage products and materials; industrial and social infrastructure systems, including power generation systems, smart community solutions, medical systems and escalators & elevators; and home appliances.
Toshiba was founded in 1875, and today operates a global network of more than 590 consolidated companies, with 206,000 employees worldwide and annual sales surpassing 5.8 trillion yen (US$61 billion). Visit Toshiba's website at www.toshiba.co.jp/index.htm.
SYS-CON Events announced today that Numerex Corp, a leading provider of managed enterprise solutions enabling the Internet of Things (IoT), will exhibit at the 19th International Cloud Expo | @ThingsExpo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Numerex Corp. (NASDAQ:NMRX) is a leading provider of managed enterprise solutions enabling the Internet of Things (IoT). The Company's solutions produce new revenue streams or create operating...
Sep. 25, 2016 12:45 AM EDT Reads: 1,924
Information technology is an industry that has always experienced change, and the dramatic change sweeping across the industry today could not be truthfully described as the first time we've seen such widespread change impacting customer investments. However, the rate of the change, and the potential outcomes from today's digital transformation has the distinct potential to separate the industry into two camps: Organizations that see the change coming, embrace it, and successful leverage it; and...
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While DevOps promises a better and tighter integration among an organization's development and operation teams and transforms an application life cycle into a continual deployment, Chef and Azure together provides a speedy, cost-effective and highly scalable vehicle for realizing the business values of this transformation. In his session at @DevOpsSummit at 19th Cloud Expo, Yung Chou, a Technology Evangelist at Microsoft, will present a unique opportunity to witness how Chef and Azure work tog...
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Data is an unusual currency; it is not restricted by the same transactional limitations as money or people. In fact, the more that you leverage your data across multiple business use cases, the more valuable it becomes to the organization. And the same can be said about the organization's analytics. In his session at 19th Cloud Expo, Bill Schmarzo, CTO for the Big Data Practice at EMC, will introduce a methodology for capturing, enriching and sharing data (and analytics) across the organizati...
Sep. 24, 2016 09:45 PM EDT Reads: 1,602
DevOps at Cloud Expo, taking place Nov 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, is co-located with 19th Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world. The widespread success of cloud computing is driving the DevOps revolution in enterprise IT. Now as never before, development teams must communicate and collaborate in a dynamic, 24/7/365 environment. There is no time to wait for long dev...
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I'm a lonely sensor. I spend all day telling the world how I'm feeling, but none of the other sensors seem to care. I want to be connected. I want to build relationships with other sensors to be more useful for my human. I want my human to understand that when my friends next door are too hot for a while, I'll soon be flaming. And when all my friends go outside without me, I may be left behind. Don't just log my data; use the relationship graph. In his session at @ThingsExpo, Ryan Boyd, Engi...
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SYS-CON Events announced today that Secure Channels will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. The bedrock of Secure Channels Technology is a uniquely modified and enhanced process based on superencipherment. Superencipherment is the process of encrypting an already encrypted message one or more times, either using the same or a different algorithm.
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The vision of a connected smart home is becoming reality with the application of integrated wireless technologies in devices and appliances. The use of standardized and TCP/IP networked wireless technologies in line-powered and battery operated sensors and controls has led to the adoption of radios in the 2.4GHz band, including Wi-Fi, BT/BLE and 802.15.4 applied ZigBee and Thread. This is driving the need for robust wireless coexistence for multiple radios to ensure throughput performance and th...
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The Internet of Things can drive efficiency for airlines and airports. In their session at @ThingsExpo, Shyam Varan Nath, Principal Architect with GE, and Sudip Majumder, senior director of development at Oracle, will discuss the technical details of the connected airline baggage and related social media solutions. These IoT applications will enhance travelers' journey experience and drive efficiency for the airlines and the airports. The session will include a working demo and a technical d...
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SYS-CON Events announced today the Enterprise IoT Bootcamp, being held November 1-2, 2016, in conjunction with 19th Cloud Expo | @ThingsExpo at the Santa Clara Convention Center in Santa Clara, CA. Combined with real-world scenarios and use cases, the Enterprise IoT Bootcamp is not just based on presentations but with hands-on demos and detailed walkthroughs. We will introduce you to a variety of real world use cases prototyped using Arduino, Raspberry Pi, BeagleBone, Spark, and Intel Edison. Y...
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Fact is, enterprises have significant legacy voice infrastructure that's costly to replace with pure IP solutions. How can we bring this analog infrastructure into our shiny new cloud applications? There are proven methods to bind both legacy voice applications and traditional PSTN audio into cloud-based applications and services at a carrier scale. Some of the most successful implementations leverage WebRTC, WebSockets, SIP and other open source technologies. In his session at @ThingsExpo, Da...
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text:
The same heavyset man, wearing a bandanna, sunglasses or other material to conceal his face, is believed to have staged three Bend bank robberies over seven months - two at the same bank, police said Thursday as they announced a $5,000 reward for tips leading to his arrest.
"It generally looks like the same person his mannerisms, his size, and the manner in which he chooses to disguise himself," said Lt. Ben Gregory.
The first holdup occurred three days before Christmas at the Bank of the Cascades branch at 61250 S. Highway 97, said Gregory. Another occurred at the same bank branch just over three months later, on April 9.
Police now say the July 30 holdup at the downtown branch of Home Federal Bank, 805 NW Bond Street, appears to have been committed by the same robber, and have just released the third surveillance photo to show the similarities.
He's described as a light-skinned, heavyset adult male, 5-foot-8 to 5-10, about 30 to 40 years of age.
"Any information out there, any information at all that someone may feel is not relevant but they may feel somewhat related too we urge them to call us," said Gregory.
Gregory told NewsChannel 21 that investigators have sent the suspects' description across the nation, but still have no solid leads.
"We are unaware of any other robberies that match this person's physical description," Gregory said.
In each case, the robber entered the bank and demanded money, Gregory said. Surveillance cameras confirmed witnesses' description of a heavyset man covering his face with some kind of material, and appearing to wear a long-sleeved shirt turned inside out.
At the request of Bend police, the Oregon Financial Institution Security Task Force has agreed to offer a $5,000 reward for any information leading to the arrest and conviction of the person or persons involved in these robberies, Gregory said.
A special tip line also has been established for the public to report information on the crimes, at (541) 330-7907.
You can also contact the Crime Stoppers hotline at 1-877-876-TIPS (or the form on KTVZ.COM's Crime Stoppers page). You can remain anonymous, and you could receive a cash reward.
Reward offered to catch Bend serial bank robber
The same heavyset man, wearing a bandanna, sunglasses or other material to conceal his face, is believed to have staged three Bend bank robberies over seven months - two at the same bank, police said Thursday as they announced a $5,000 reward for tips leading to his arrest.
Copyright 2012 KTVZ. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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text:
Submit News
NVIDIA Mirrors Qualcomm's Hot Streak With Earnings Surprise of Its Own
Jason Mick
November 9, 2012 10:31 AM
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NVIDIA unleashes its metaphorical can of "whoop ass"
There was a time -- back in 2010 -- when NVIDIA Corp. (
) looked a bit lost. A resurgent Radeon brand, now owned by Advanced Micro Devices, Inc. (
), was
punishing it in the discrete graphics market
with the Radeon HD 5000 series devices, and analysts were scratching their heads in puzzlement at NVIDIA's focus on GPU computing.
And NVIDIA's
Tegra system-on-a-chip effort
was largely written off, as NVIDIA couldn't seem to figure out what it wanted to do with it -- netbooks? Mobile devices? No one could quite tell.
I. A Young Power in the Mobile Market
Fast-forward three years and NVIDIA is in a far different -- and far better -- position. GPU computing is an exploding field and NVIDIA has
large purchase orders
from the hottest new deployments. It's back to
scoring wins
in the gaming graphics market.
And most importantly Tegra has exploded, seizing a commanding stake in the mobile device system-on-a-chip (SoC) market.
In calendar/fiscal Q3 2012, NVIDIA
large earnings and revenue surprises, delivered thanks to its SoC and GPU market gains. Revenue fell in at $1.204B USD (GAAP), pleasantly above the consensus of $1.192B USD estimated by 33 analysts
surveyed by
The Financial Times
Tegra 3 drove NVIDIA to a big profit surprise.
much like system-on-a-chip archrival Qualcomm
, Inc. (
), the biggest surprise lay not on the revenue, but on the net income (profit) front. NVIDIA pocketed a whopping $209M USD, ($0.33 USD/share), above the most optimistic estimate of $203M USD ($0.32 USD/share) from the analyst crowd, and even higher above the average estimate of $187M USD.
NVIDIA's at times colorful and divisive chief executive officer and president, Jen Hsun Huang crowed, "Investments in our new growth strategies paid off this quarter in record revenues and margins. Kepler GPUs are winning across the special-purpose PC markets we serve, from gaming to design to supercomputing. And Tegra is powering some of the most innovative tablets, phones and cars in the market."
The chipmaker decided to share the wealth with its shareholders, offering up a 7.5 cent dividend.
Capital expenditures for NVIDIA have grown as the company sharpens its focus on bleeding edge system-on-a-chip research. NVIDIA estimates that it will spend $50M to $60M USD next quarter on R&D and other CAPEX.
II. Gloom for Q4, But It Could be Worse
Looking ahead, while NVIDIA's Q3 results mirror Qualcomm's, its Q4 estimates are
than its rivals. NVIDIA estimates that revenue will dip to between $1.025B and $1.175B USD on a slowing global economy, versus the traditional bump in the holiday season.
One possible reason why NVIDIA is more worried than Qualcomm is that much of its earnings are still driven by sales of high-end (
) hardware (GPUs) for traditional consumer and enterprise systems. When the economy slumps, these sales tend to suffer the most, as users consolidate their buying power towards cheaper mobile devices. In that regard, a mix mobile/traditional chipmaker like NVIDIA will likely be hurt more by a downturn than a solely mobile-centric chipmaker like Qualcomm.
A slowing economy is expected to dent NVIDIA's Q4 earnings.
However, NVIDIA's better-than-expected earnings do represent good news in a couple of ways. First, NVIDIA and Qualcomm represent a reasonably good barometer by which to gauge the health of the mobile market. And by the looks of it, mobile is flourishing at a time when other less fortunate markets find themselves facing tough financial questions.
Second, NVIDIA enjoys a key psychological advantage over Qualcomm in that it's pumping out quad-core units of its latest and greatest Tegra 3 processor, while Qualcomm's current Snapdragon 4 offerings are mostly constrained to dual-core CPUs. That's a big reason why NVIDIA is thus far
outpacing Qualcomm in design wins
in the emerging Windows RT ARM-based laptop/hybrid device market.
Traditional PCs demand more power, and NVIDIA has been the most aggressive about push higher core-counts in its mobile chips. That decision will likely pay off for the company, and help it ride out the storm ahead in the discrete graphics market.
FT [analyst estimates]
remember me
This article is over a month old, voting and posting comments is disabled
RE: half-empty vs cup half-full
Only at home, not in the pro market. Nvidia RIGHTLY aimed their home cards at GAMES. Because guess what? We play games more than we fold at home...LOL. We play games more than we try to get bitcoins...LOL. I don't pay $300 for a card to do anything other than play games. Easily had bitcoin party is over, and who the heck runs their gpu's at 100% in todays economy to solve cancer for someone else? :) Run up my electric bill so you can make a billion on your next drug you try to sell me? SCREW YOU company X. :)
Having said that, I'm seriously happy Nvidia decided Diablo3 should run 116% faster than Radeon's instead of being great at solving cancer on my home PC :) Well DUH.
For real work - K5000+Tesla until a Quadro110 comes out. There's a reason the combo will set you back $5K. :)
These are not radeons ;) When you're running a $1500-20K software on your system in the hopes of making millions I don't expect it to run on my puny $300 home card as if it was a $3300 K20 coming next month. They're not designed for the same things.
But if it makes your fanboy side feel better, you just keep saying radeon is faster
. I've never even installed it, and most gamers don't even know what it is. Ask 10 people on the street what a bitcoin is...ROFL. Heck when fox news asked a bunch of people on the street if obama won the debate (BEFORE it actually happened) most said "obama won..."...ROFL. Followed by why did you think he won last night? "umm, he just had the better ideas, and I like what he had to say"...ROFL...Really? Then they asked, so did you watch the whole thing? "Oh yeah, obama did great"...ROFL. I wish they would have told them it wasn't going to happen until the NEXT DAY to see the look on their faces. People don't even know what's going on today. A week later they asked they asked something like "what do you think of obama picking romney as his running mate"..."It was a great idea, it really shows he bipartisan". Just watch some watters world for some great laughs. People didn't even know who was in the race.
I'd guess if Watters went out on the street and asked people what they thought of the new "gpgpu technology and do you think it will really help us go green and get better gas mileage without OIL?", they'd most likely say "oh yeah those new gpgpu's are great green tech, and will really help us get off oil"...ROFL. 95% of america has no idea what gpgpu even is let alone that AMD has a good home card for it ;) Their 157mil loss and market share loss to Nvidia says "it's the games stupid!". Just like the economy :) Xmas won't be good too AMD, but winning 13/16 games like NV did in the mobile grudge match gets into everyone's memory article after article. That sells HOME CARDS. People think if you have the crown, all your cards must win. It's pretty clear NV has the crown. The 65% market share vs. AMD's share says it all. The $225mil AMD owes GF for Dec31st won't help the quarter for AMD at all either. I expect a 300-400million loss for AMD for xmas Q, and this is supposed to be the BEST quarter for all gizmo/gadget makers. On the other hand I expect NV to have 100-200mil profit. That's a HUGE difference there guy.
AMD's cup is 7/8ths empy, while NV's is 3/4 full :)
AMD 64% chance of bankruptcy in the next 2yrs. It was 51% before the Q loss last month. Note NV is 1% chance (and only 1% because they assign NOTHING 0%). The numbers don't lie. You need to start reading balance sheets along with your benchmarks ;) Just a thought.
I've predicted it on here/elsewhere many times in the last year, amd bankrupt by xmas 2014 or bought. If they wait too long it will only be patents being bought rather than their pipeline (stop cutting prices AMD! You might actually make money then). Even intel went from 1% a few months ago to 5% chance now that everyone is entering the server/desktop market (server 1st, though, NV has Denver for desktop probably earlier than most since it sampled in may on 20nm Samsung Austin TX plant). NV goes to world class fab at 20nm, while the rest fight over crap class TSMC/GF. I can't wait to see what a 20nm Kepler does to noise and heat :) Watch for that next xmas right after Denver hits. Denver is the testing ground for Nvidia's next step, which is Kepler (or some variant) on 20nm at samsung. Samsung will use the much larger Kepler to take up the slack for apple's millions of chips leaving their fabs no matter what Tegra does. All the kepler variants (home/pro) will take up a lot of wafers. At the same time Samsung will get a leg up on Apple's A7 as they try to get TSMC to actually get a chip right for once. Good luck apple/amd/qualcomm ;) TSMC sucks.
"We do believe we have a moral responsibility to keep porn off the iPhone." -- Steve Jobs
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The Design Lives Here initiative is an innovative partnership between WQED Multimedia, the Engineers' Society of Western Pennsylvania, MSA, and Glaxo Smith Kline Consumer Healthcare and American Bridge. Design Lives Here is an education outreach program that promotes learning about engineering via interactive teaching, mentoring, and challenge activities. The project was piloted during the 2009-2010 school year; educators from more than 30 schools received training, representing an educational impact on approximately 600 students. Five schools were invited to participate in a special engineering event held in May 2010, which was attended by 70 students in grades five through 11. Watch some highlights of the event:
After the overwhelming success of last year's Design Lives Here events, WQED is excited to expand the initiative into more schools, create opportunities throughout the year for student learning, and create a web-based informational infrastructure to foster engagement and interest in engineering. Participating schools will hold monthly engineering qualifying challenges that incorporate Design Squad curriculum and use materials provided by WQED. The initiative will culminate in an end-of-school-year student Challenge Event, a day of engineering fun, mentorship opportunities, viewings of the television show, and more, all in the historic Fred Rogers Studio at WQED's Oakland headquarters.
Interested in learning more about Design Lives Here? Email us!
Download the Design Lives Here Invitation [pdf]
Download the Design Lives Here Application [pdf]