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Quadruple Helices Appear To Have Role...
Expanding Use of NGS Has Largely...
LC-MS Gains Favor Due To the...
As Immunotherapy Revolutionizes the Cancer Treatment...
When asked about the daily reality of developing DNA sequencing technology for a high-throughput sequencing center—a job that I've enjoyed every minute for the past 20 years—I typically respond, "Never a dull moment!"
When I find time to reflect upon the amazing trajectory of innovation that has brought the field to the current state, I marvel at what has been accomplished in a relatively short time period. Think about it.
Fred Sanger and colleagues first began publishing DNA sequencing methods in the mid-1970s, culminating in their description of the dideoxynucleotide chain termination method in PNAS in 1977.1 I learned DNA sequencing in the mid-1980s from Bruce Roe, my Ph.D. mentor, who learned from Fred Sanger and Alan Coulson.
At that time, the state-of-the-art included labeling four separate reactions for each
template with 32P-dATP and the Klenow fragment of E. coli DNA polymerase, separation on hand-assembled and poured polyacrylamide-urea gels, and autoradiography. Sequence data was entered by one hand into the computer (thankfully, the QWERTY keyboard contains the A, C, G and T keys on the same half!), while peering at the gel on a fluorescent lightbox and keeping track with the other hand.
Sounds like ancient history, but that was less than 30 years ago. In retrospect the dramatic changes in DNA sequencing in terms of its scale of execution, the interdisciplinary efforts required to produce, analyze, and interpret the data, the expanding impact of DNA sequencing on biological research, and, ultimately, on our economy have compounded at an amazing rate in that time frame.
This acceleration seems quite likely to continue as the pace of sequencing and its reach across the biological sciences shows no sign of slowing. Research activities in several areas that have been transformed by next-generation sequencing technology may be illustrative of this trajectory and its predicted acceleration.
In human metagenomics studies, for example, the sampling of bacterial, viral, and eukaryotic organisms taken from a specific area of the human body by gross sampling methods and DNA isolation has been greatly accelerated by next-generation sequencing (NGS) technology.
Generating NGS data from these metagenomic isolates addressed the two major issues—cost and ease of data generation—that kept early metagenomic studies from achieving their full potential.
With the decreased cost of NGS reads, significantly deeper sampling of each population isolate can be achieved and hence minor species detected. The digital nature of these reads further enables a measure of the relative proportions of each population member.
The simplicity of NGS library preparation, the ability to make these libraries from tiny input amounts of DNA, and the elimination of a bacterial cloning intermediate have been invaluable to improving the representation of all species present in the populations sampled and to expanding the types of samples we can address.
The development of data-analysis approaches that encompass the increasing size of the sequence datasets that result from deep NGS sampling and that can accurately mine information from them has re-engaged computational biologists and has resulted in a staggering amount of innovation.
Resulting "big science" projects such as the NIH's Human Microbiome Project, Europe's MetaHit, and other international projects, as well as the research of independent investigators, have begun to define bacterial diversity in human health and disease.2-3
Interestingly, we now have a bacterial census of the intestines of cats and dogs4, pigs5, and the octopus.6 Novel pathogenic viruses have been discovered by mining metagenomic datasets, and etiologic agents have been identified in disease outbreaks.7-8
By studying RNA isolates converted to cDNA from various sources, a new experimental approach called "metatranscriptomics" has resulted, and can be applied to characterize the metabolic potential of each population.
Metagenomics also has been applied to characterize environments unrelated to human health, such as soils9-10, lakes11, and thermal springs in Russia12, among myriad others. In fact, a quick search of PubMed with "metagenomic" reveals 1,382 references. Most have been published since 2005, across an incredible breadth of topics that reflect the explosion of this scientific endeavor in basic biological discovery, data analysis, data mining, and methods development.
As the transformation of metagenomics by NGS and advanced analytical approaches continues, it will be interesting to see its impact on diverse areas such as food safety monitoring (evidence the need for continuing vigilance as yet another E. coli strain impacts human health in Europe), and pharmaceutical product development and quality control (such as in vaccines or other live-cell products).
Another possible use will be diagnosis for optimal antibiotic treatment in patients affected with pathogens known to harbor a spectrum of antibiotic resistance such as methicillin-resistant Staphylococcus aureus (MRSA). There are numerous other applications.
Elaine R. Mardis, Ph.D. ([email protected]), is an associate professor of genetics and molecular microbiology, co-director, The Genome Institute of Washington University School of Medicine.
Elaine R. Mardis, Ph.D. ([email protected]), is an associate professor of genetics and molecular microbiology, co-director, The Genome Institute of Washington University School of Medicine.
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ZERO AUDIO-ear stereo headphone carbo Tenore ZH-DX200-CT
"Saw some glowing reviews for these, and thought that for under $40 on Amazon it's well-worth finding out what the fuss was about - in short: well worth it! Set-up: LG G4 > USB Audio Player Pro (FLAC; ALAC) > Audioquest Dragonfly Black 1.5 Packaging/bundling They arrived from Amazon in a plastic box, but come with a neat cloth carrying pouch which is super handy - I use..." --Mightygrey
Zero Audio ZH-BX300
Zero Audio ZH-BX300
Zero Audio ZH-BX500
"A mids-focused specialist with a little bass thump and smooth, relaxed treble (recessed, but still has some detail). Not an especially engaging sound (a little too relaxed maybe). Decent across genres, but tend to congestion during busy/noisy passages. I find them particularly useful for low volume podcast legibility, though with podcasts that are poorly leveled, subject to intrusive volume..." --Raketen
Mushroom Earbud Design Clip
Budclicks patented the ability to click charms to earbuds. They allow kids, tweens, and adults to style up those bland white earbuds. The Budclick mount works on iPod and iPhone style white earbuds created by Apple. With over 150 million of these earbuds on the market Budclicks have appeal to just about everyone. Budclicks has found the largest audience in music listeners on the go. Whether on...

subset: commoncrawl


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MGT514: IT Security Strategic Planning, Policy and Leadership
- Contents | Schedule | Additional Info
- Instructor: Mark Williams
- 30 CPEs
- Laptop Not Needed
Instructor was great-very active engaging and thorough. Great industry examples and well led conversation.
Jason Popp, Nordstrom Inc.
Really good case studies and examples which prompted useful class discussion -this helps to --- understanding.
Alexis Brownings, CERT-UK
Mastering the Strategic Planning Process
Strategic planning is hard for people in IT and IT Security because we spend so much time responding and reacting. Some of us have been exposed to a SWOT or something similar in an MBA course, but we almost never get to practice until we get promoted to a senior position, and then we are not equipped with the skills we need to run with the pack.
In this course you will learn the entire strategic planning process: what it is and how to do it; what lends itself to virtual teams; and what needs to be done face to face. We will practice building those skills in class. Topics covered in depth include how to plan the plan, horizon analysis, visioning, environmental scans (SWOT, PEST, Porter's etc.), historical analysis, mission, vision, and value statements. We will also discuss the planning process core, candidate initiatives, the prioritization process, resource and IT change management in planning, how to build the roadmap, setting up assessments, and revising the plan.
We will see examples and hear stories from businesses, especially IT and security oriented businesses, and then work together on labs. Business needs change, the environment changes, new risks are always on the horizon, and critical systems are continually exposed to new vulnerabilities. Strategic planning is a never-ending process. The planning section is hands-on and there is exercise-intensive work on writing, implementing, and assessing strategic plans.
Creating Effective Information Security Policy
Policy is a manager's opportunity to express expectations for the workforce, to set the boundaries of acceptable behavior and empower people to do what they ought to be doing. It is easy to get wrong. Have you ever seen a policy and your response was, "No way, I am not going to do that?" Policy must be aligned with an organization's culture. We will break down the steps to policy development so that you have the ability to develop and assess policy successfully.
Developing Management and Leadership Skills
The third focus of the course is on management and leadership competencies. Leadership is a capability that must be learned, exercised and developed to better ensure organizational success. Strong leadership is brought about primarily through selfless devotion to the organization and staff, tireless effort in setting the example, and the vision to see and effectively use available resources toward the end goal. However, leaders and followers influence each other toward the goal; it is a two-way street where all parties perform their functions to reach a common objective.
Effective leadership entails persuading team members to accomplish their objectives while removing obstacles and maintaining the well-being of the team in support of the organization's mission. Grooming effective leaders is critical to all types of organizations, as the most effective teams are cohesive units that work together toward common goals with camaraderie and a can-do spirit!
Leadership tends to be a bit "squishy" and courses covering the topic are often based upon the opinions of people who were successful in the marketplace. However, success can be as much a factor of luck as skill, so we base this part of the course on five decades of the research of social scientists and their experiments going as far back as Maslow and on research as current as Sunstein and Thaler. We discuss leadership skills that apply to commercial business, non-profit, for-profit, or other organizations. This course is designed to develop existing and new supervisors and managers who aspire to go beyond being the boss. It will help you build leadership skills to enhance the organization's climate and team-building skills to support the organization's mission, its growth in productivity, workplace attitude/satisfaction, and staff and customer relationships.
|Course Contents
|MGT514.1: An Approach to Strategic Planning
|Mark Williams
Mon Feb 16th, 2015
Our approach to strategic planning is that there are activities that can be done virtually in advance of a retreat, and then other activities are best done in a retreat setting. On the first day, we will talk about some of the activities that can be done virtually.
CPE/CMU Credits: 6
|MGT514.2: Planning To Ensure Institutional Effectiveness
|Mark Williams
Tue Feb 17th, 2015
This will include the retreat section of the course where we do the core planning activities of candidate selection, prioritization, and development of the roadmap.
CPE/CMU Credits: 6
|MGT514.3: Security Policy Development
|Mark Williams
Wed Feb 18th, 2015
You will experience the most in-depth coverage of security policy ever developed. By the end of the course your head will be spinning. Students and other SANS instructors who have seen the scope of the material have the same comment, "I never realized there is so much to know about security policy." Any security manager, anyone assigned to review, write, assess or support security policy and procedure, can benefit from Policy in Depth. You will learn what policy is, positive and negative tone, consistency of policy bullets, how to balance the level of specificity to the problem at hand, the role of policy, awareness and training, and the SMART approach to policy development and assessment. We cover different levels of policy from Information Security Management System (ISMS) governing policy to detailed issue-specific policies like acceptable use, approved encryption and end of life disposal of IT assets.
CPE/CMU Credits: 6
|MGT514.4: Comprehensive Security Policy Assessment
|Mark Williams
Thu Feb 19th, 2015
In the policy section of the course, you will be exposed to over 100 different policies through an instructional delivery methodology that balances lecture, labs, and in-class discussion. We will emphasize techniques to create successful policy that users will read and follow; policy that will be accepted by the business units because it is sensitive to the organizational culture; and policy that uses the psychology of information security to guide implementation.
CPE/CMU Credits: 6
|MGT514.5: Leadership and Management Competencies
|Mark Williams
Fri Feb 20th, 2015
Essential leadership topics covered here include: leadership development, coaching and training, employee involvement, conflict resolution, change management, vision development, motivation, communication skills, self-direction, brainstorming techniques, benefits, and the ten core leadership competencies. In a nutshell, you'll learn the critical processes that should be employed to develop the skills and techniques to select, train, equip, and develop a team into a single cohesive unit with defined roles that operate together in harmony toward team-objective accomplishment.
There are three goals for the leadership component of this course:
CPE/CMU Credits: 6
|Additional Information
|Laptop Not Needed
Pencil and paper would suffice for the labs, but we recommend a laptop with a word processor.
If you have additional questions about the laptop specifications, please contact email@example.com.
|Who Should Attend
This course is designed and taught for existing, recently appointed, and aspiring IT and IT Security managers and supervisors who desire to enhance their leadership and governance skills to develop their staff into a more productive and cohesive team.
|What You Will Receive
In this course, you will receive the following:
|You Will Be Able To


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Published 5:33 PM CDT Mar 26, 2013
Waukesha police are investigating an alleged sexual assault at a slumber party.
WISN 12 News' media partner the Waukesha Patch reports that a mother told police that her daughter woke to her friend's stepfather touching her.
The mother said the stepfather gave marijuana and alcohol to the minors during the two-day sleepover.
Waukesha police are still looking into it and are releasing no other information at this time.
You can read more on the story here.
Copyright 2013 by WISN.com All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Mark your calendars and start planning: Spring's almost here
Complaining about winter and all the hassles it brings is part of an Erieite's DNA.
It's also a waste of time: The snow is bound to fall and keep falling, sometimes into April, along with the mercury every year. As of Wednesday, Erie was the second-snowiest city in the Golden Snow Globe contest for cities larger than 100,000 people. The 82.1 inches that have fallen at Erie International Airport this season put us behind only Syracuse, N.Y., with 85.6 inches.
It's enough to make you want to hibernate.
But rejoice! Spring arrives March 20, or at least that's what the calendar promises.
Here's what I'm looking forward to:
- No more shoveling. Or snowblowing. Or scraping ice off the car. Is there a worse way to start the day?
- Eating ice cream at Sara's.
- Birds chirping.
- Packing away the sweaters, gloves, scarves and hats that threaten to bury me in a winter avalanche every time I open the living room closet. I'm ready for short sleeves and baseball games.
- Turning down the heat, throwing open the windows and airing out the house. I won't cry about the cheaper gas and electric bills, either.
- Walking Presque Isle without the parka.
- Gardening. I don't have a green thumb, but I'm going to try to make a few well-intentioned trips to local greenhouses anyway. Nothing says spring like flowers in the window boxes.
- Hitting the playground with the kiddo. We both have serious cases of cabin fever. I'm ready for the swings to reappear at Frontier Park. She's ready to run through sprinklers.
- Hamburgers and hot dogs on the grill. The smell of charcoal.
- No more mopping puddles left by snow boots on my kitchen floor.
What are you most looking forward to?
ERICA ERWIN can be reached at 870-1846. Send e-mail to email@example.com.


text:
Source: Apple
quote: The 3GS, a phone that will be 4 years/generations old by the time iOS 6 is released, will get this update.
quote: Those are subjective opinions formatted as facts. Thus are rejected.
quote: Yeah clearly they should have done things differently years ago based on your hindsight-tinted observations from today.
quote: I called all of the above after the first year of Android, the writing was on the wall. I heard the same denial and excuses back then but obviously I was right.
quote: I'm sure after the first year of Android, you also claimed it would never reach something like the 65% marketshare it has now. You sure as hell never thought it would.


text:
Systemwide Events Calendar
FilAm HistoryFest 2013: Filipino Martial Arts in HawaiiOctober 27, 3:30pm - 6:30pm
Filipino Community Center, 94-428 Mokuola Street, Waipahu, Hawaii
Eskrima is a martial arts originating from the Philippines that has spread throughout the world. In Hawaii and the U.S., eskrima (also known as kali, arnis and FMA) was introduced through plantation and migrant laborers. FilAm HistoryFest 2013 celebrates eskrima with presentations and demonstrations by six Hawaii-based eskrima schools: Bandalan Doce Pares Eskrima, Del Mar School of Filipino Martial Arts, General Ablen's School of Derobio Escrima, the Hawaii Filipino Martial Arts School, the Hawaii Organization of Pilipino Eskrima, and Sinao Tjakalele. A brief discussion session accompanies the demonstrations. FilAm HistoryFest 2013 is organized by the Filipino-American Historical Society of Hawaii and cosponsored by the UHM Office of Multicultural Student Services.
Ticket Information
Admission is free and open to the public.
Event Sponsor
Office of Multicultural Student Services, Manoa Campus
More Information
Clement Bautista, 256-4380, email@example.com
|Sunday, October 27
|Diamond Head Beach Cleanup
Manoa Campus, Diamond Head Beach Park 3451 Diamond Head Rd
|The Wild Party
Manoa Campus, Earle Ernst Lab Theatre
|Intramural Sports - Basketball
Maui Campus, Baldwin High School Gymnasium
|FilAm HistoryFest 2013: Filipino Martial Arts in Hawaii
Filipino Community Center, 94-428 Mokuola Street, Waipahu, Hawaii
- Highlighted dates have scheduled events.
- Select the date to view all events for that day.
Ongoing Events
- The Wonder of Learning: the Hundred Languages of Children Exhibit
- Waikiki Parc Features Nicole Naone
- Course Reserves Deadlines and Information
- Red Hat System Administration I
- EWC Arts Exhibition: Bollywood & Beyond: Costume in Indian Film
- Kalaupapa -- A Source of Light, Constant and Never-Fading
- Convergence: Glitch_Click_Thunk, Featuring Mark Amerika
- Trip Around the Island
- Trip Around the Island exhibit
- Conflict Resolution Day Book Displays
- UHM Costume Museum Exihibition


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Systemwide Events Calendar
Islands of Contention: The Struggle for Self-Determination in OkinawaOctober 13, 1:00pm - 3:00pm
Manoa Campus, Center for Korean Studies Auditorium
Join us for a forum presenting several documentary film clips to show a big picture of sovereignty movements in Okinawa. Growing public discussions and social movements about Okinawan self-determination are placed in the complexity of international affairs.
Free and open to the public. Parking is free on Sunday.
Event Sponsor
Center for Okinawan Studies / Office of Multicultural Student Service, Manoa Campus
More Information
Center for Okinawan Studies, 956-0902 / 956-5754, email@example.com, http://manoa.hawaii.edu/okinawa/wordpress/wp-content/uploads/2013/08/FLYER_revisedOct1.3.pdf
|Sunday, October 13
|6th Annual APIL Run for Justice 5K
Manoa Campus, 1500 University Ave. (Bachman Lawn on the Corner of University and Dole
|MPLA Volunteer Event
Manoa Campus, Contact email@example.com for more information.
|Islands of Contention: The Struggle for Self-Determination in Okinawa
Manoa Campus, Center for Korean Studies Auditorium
|Intramural Sports - Basketball
Maui Campus, Baldwin High School Gymnasium
- Highlighted dates have scheduled events.
- Select the date to view all events for that day.
Ongoing Events
- The Wonder of Learning: the Hundred Languages of Children Exhibit
- Waikiki Parc Features Nicole Naone
- Course Reserves Deadlines and Information
- Red Hat System Administration I
- EWC Arts Exhibition: Bollywood & Beyond: Costume in Indian Film
- Kalaupapa -- A Source of Light, Constant and Never-Fading
- Convergence: Glitch_Click_Thunk, Featuring Mark Amerika
- Trip Around the Island
- Trip Around the Island exhibit
- Conflict Resolution Day Book Displays
- Masquerade Mixer


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- Text Size:
- ASmall Text
- AMedium Text
- ALarge Text
A Connecticut man named Noel was arrested after scaling a Christmas tree in a public park.
Police cut electricity to the tree in New Haven Green, a 16-acre park in New Haven near Yale University, and talked with Noel Delgado to persuade him to come down, The Associated Press reported.
Delgado was carrying two banners and shouting about various causes.
He was charged with breach of the peace and refused medical treatment at the scene, the AP reported.
The views expressed are not those of this site, this station or its affiliated companies. By posting your comments you agree to accept our terms of use.blog comments powered by Disqus


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The U.S. Consumer Product Safety Commission (CPSC) and the Juvenile Products Manufacturers Association (JPMA) are warning parents and caregivers that cords on baby audio and video monitors present a strangulation hazard to infants and toddlers when placed within a child's reach.
Live Webcasts
Video: CPSC Chairman: Baby Monitor Cords Are Serious Safety Issue
Safety Alert: Safe and Sound Zone
Crib Information Center
In this edition of Recall Roundup: Kidde recalls fire extinguishers, Mohawk recalls area rugs, and Sunbeam recalls Holmes oil-filled heaters.
The staff will brief the Commission on a draft final rule that would establish a mandatory safety standard for frame child carriers pursuant to section 104 of the Consumer Product Safety Improvement Act of 2008.
On average, one child dies every two weeks when a TV, furniture or appliance falls onto him or her. By anchoring large furniture, televisions and appliances, these terrible tragedies can be prevented.
En promedio, un niño(a) muere cada dos semanas cuando un televisor, mueble o electrodoméstico le cae encima. Estas terribles tragedias pueden prevenirse al fijar grandes muebles, televisores y electrodomésticos.
Interested persons present oral comments to CPSC Commissioners concerning the notice of proposed rulemaking (NPR) the Commission issued proposing a standard to reduce the risk of injury associated with recreational off-highway vehicles (ROVs).
CPSC Commissioners vote on the Phthalates Notice of Proposed Rulemaking.
CPSC Commissioners vote on the Fiscal Year 2015 Operating Plan.
This month on Recall Roundup: Graco recalls strollers,McDonald's recalls toy whistles, and Toys R Us recalls kids' sandals.
The link you selected is for a destination outside of the Federal Government. CPSC does not control this external site or its privacy policy and cannot attest to the accuracy of the information it contains. You may wish to review the privacy policy of the external site as its information collection practices may differ from ours. Linking to this external site does not constitute an endorsement of the site or the information it contains by CPSC or any of its employees.
Click Ok if you wish to continue to the website; otherwise, click Cancel to return to our site.


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Quality Education in the Benedictine Tradition
Oct. 8
Saint Vincent College Professor of Music Fr. Stephen Concordia, O.S.B., right, directs Saint Vincent College students Jonathon Jacobeen, left, and Brian Myers, center, who will perform with the Saint Vincent Schola Gregoriana in three performances at Heinz Hall with the Pittsburgh Symphony Orchestra on October 12, 13 and 14. The principal conductor of the orchestra, Manfred Honeck, invited Saint Vincent for the second time to provide a Gregorian chant schola to sing as part of Honeck's reading of the Requiem Mass of Wolfgang Amadeus Mozart. Entitled by Maestro Honeck "Requiem Mass for Mozart," the performances include the Requiem in its entirety, together with other sacred music of Mozart, and will incorporate Scriptural readings, biographical readings from the letters of Mozart, and a Gregorian chant schola. The Saint Vincent Schola Gregoriana is composed of 21 singers and includes Saint Vincent Benedictine monks and area residents. Mr. Jacobeen is a junior philosophy major and music minor from Manassas, Virginia. Mr. Myers, a senior music major studying organ, is from Saint Marys, Pennsylvania.
Follow us on Twitter: @SVCPublicity Like us on Facebook: Saint Vincent College Public Relations


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1st Kingswood BP Scouts
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on October 8, 2012 - 8:38 AM
, updated October 8, 2012 at 9:46 PM
ALBANY – Raising much-needed money to mount a serious campaign against incumbent Sen. Mark Grisanti will become even more difficult for Democrat Michael Amodeo following release of a poll today showing him badly trailing the Buffalo Republican.
The Siena College poll found 47 percent of likely voters in the Erie County district support Grisanti, while Amodeo, a Hamburg lawyer, is far behind with just 23 percent.
The presence of other challengers in the race is having a clear effect: Charles Swanick, the former chairman of the Erie County Legislature who lost the Democratic primary to Amodeo but is still in the race on the Conservative Party line, was supported by 17 percent of voters. It is uncertain how much of a real campaign Swanick is running, based on his new – and lackluster – fundraising and spending report filed late Friday with the state elections board, but pollsters said they believe Swanick's presence is helping Grisanti.
Gregory Davis, a political unknown attorney running on the Working Families Party line, drew 6 percent.
The poll's release came as Gov. Andrew M. Cuomo, who has been criticized by some Democrats for being too cozy with Senate Republicans, endorsed his first Senate Democrat – an incumbent lawmaker from Queens. But Republicans said the governor's move, which they insisted was not a surprise since the lawmaker, Joseph Addabbo, backed Cuomo's plan legalizing gay marriage rights last year, could now give the governor some political breathing room to endorse some Senate Republicans, such as Grisanti.
"It could,'' acknowledged the Senate's deputy majority leader, Thomas Libous, a Binghamton Republican.
Libous said the governor has already offered "somewhat of an endorsement" of Grisanti through local appearances during the year and by helping him to get approved important pieces of legislation. He noted Grisanti, as well as Libous himself, used Cuomo's image in recent campaign television ads – a move Cuomo did not protest.
"I'm not certain the old-fashioned, 'I support Joe Jones' has to be done. There are other ways you can show support … and I think the governor has been supportive of key members of our [GOP] conference, and Mark is one of them," Libous said.
Cuomo was coy Monday about possible backing of other Senate Democrats or Republicans, saying any other endorsements in the weeks ahead would be made on "a case-by-case" basis.
Grisanti, a former Democrat who turned Republican to run for the seat two years ago, is running in a newly redrawn 60th Senate district – which saw Niagara County carved out of it and several towns south of Buffalo plunked in. The new district is two-to-one Democratic over Republican in terms of voter enrollment and, according to the poll, favors President Obama over Republican Mitt Romney.
Steve Greenberg, the Siena pollster, said the field of candidates is "splitting the anti-Grisanti vote" in the campaign.
Democrats will likely use the poll results to call Swanick a spoiler whose presence is helping Grisanti. Grisanti got backing from 61 percent of Republicans polled in the district, 59 percent of independents and 34 percent of Democrats.
Grisanti has been politically cozy with the Democratic governor, whose popularity is high in the district despite losing all Western New York counties in his election campaign two years ago.
"If Grisanti was opposed by a single candidate, this race might be more interesting since his support falls below 50 percent," Greenberg said, adding Grisanti "appears to be in a commanding position."
For Amodeo, name recognition is clearly a problem: the poll found him to be unknown to more than half the likely voters. With little sign, so far, of major Democratic Party money coming into the race to help him, Amodeo's challenge is how to raise his profile in so little time with not enough funds to launch a serious advertising campaign.
Grisanti has a 59 percent favorability rating among voters. At 25 percent, Amodeo trails the 30 percent favorability ranking given Swanick, the poll found.
In the 60th, Obama leads Romney by 54 percent to 40 percent, a level that, ordinarily, would be seen as a benefit to a challenger like Amodeo.
Grisanti and Amodeo did not return calls.
Nearly one-third of voters in the district said job creation is the single most important issue, double that of education or health care and triple the level for property taxes.
A Senate Democratic spokesman, in a written statement, did not specifically address the poll's findings for the 60th Senate District. "There remain a half-dozen Republican-held districts in play yet to be publicly polled. With campaigns just beginning in earnest and funding differences greatly reduced, Democrats are well positioned to gain the seats necessary to reclaim the majority," said Mike Murphy, the Democratic spokesman.
In the response from the Senate Republicans, spokesman Scott Reif used Cuomo's name twice in two sentences – once to note Amodeo's opposition to part of Cuomo's property tax law and the other to note Grisanti's work with Cuomo to pass a University at Buffalo expansion law last year.
The Cuomo endorsement of Addabbo in Manhattan before the start of today's Columbus Day parade is certain to give the governor some cover against Democrats upset that he has been too keen on seeing Republicans keep control of the Senate. The governor's chief gift to the Republicans came this year when he approved a set of new Senate district boundary lines that Democrats say was gerrymandered to help the GOP. The Siena poll Monday found Addabbo in a statistical tie with his GOP challenger.
On the fundraising side, Senate Republicans last week pumped $100,000 into Grisanti's campaign. With a two-to-one Democratic enrollment edge in the district and local Democrats vowing to mount a serious get-out-the-vote effort for Amodeo on election day, Libous, the Binghamton Republican, insisted Monday the help for Grisanti will not slow despite the new poll showing him with a big lead.
Last week, Amodeo said his new filing with the state Board of Elections would show about $10,000 in the bank; his report, due last Friday, was not listed on the board's website Monday.
Grisanti's report on Friday showed him with $50,000 on hand. He raised only $3,600 in the past several weeks, but his overall balance was pumped up by the transfer of $100,000 from the central Senate Republican account in Albany into his Buffalo campaign bank account. The GOP two weeks earlier had given Grisanti $78,000.
The $100,000 – the largest donation by the Senate Republicans to one of their own in the past three weeks – was needed by Grisanti. His campaign shows him spending $160,000 during the brief election window after the primary – all but $10,000 of that on a television ad campaign.
Swanick's new filing shows hardly any activity. He raised only $2,500 from one source -- an individual living in Virginia. He got $600 from in-kind contributions, mostly for office space in Buffalo. And he still lists the $35,000 in liabilities – to himself – from loans he provided the campaign before the primary. His campaign listed $600 in expenses the past three weeks, though the details were not listed on the election board's website. He reported $12,807 on hand. He did not return calls for comment today.
Senate Democrats say they want to evidence Amodeo has a serious chance to beat Grisanti before investing money in his campaign. Last week, Senate Democrats reported spending $180,000 on behalf of nine Democratic candidates; Amodeo was not among them.
email: firstname.lastname@example.com


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January 9, 2008
The Weather Outside Is...?
25 comments:
I hope he feels better soon!ReplyDelete
Last week was like 10 degrees here and yesterday we had a record high of 66! Craziness!ReplyDelete
Thinking of little Carter!
Jane, Pinks & Blues
Oh, I hope Carter is okay. Let me know what the Dr says.ReplyDelete
Sprinter, hee hee! I remember sprinter.ReplyDelete
Poor baby! I've got an ear infection that hurts BAD and I've been using the ear pain relief by Similasan and it is wonderful! The pain is gone within a few minutes of using it, and best of all, it's all natural! I found it at Walgreens. I hope he feels better soon, for his sake and yours!ReplyDelete
Poor Carter I hope he feels better soon.ReplyDelete
And this crazy weather figures out what it's going to be.
Hopefully the sunshine can cheer him up a bit. Poor guy. :(ReplyDelete
We're praying for Carter!ReplyDelete
85 and sunny here.ReplyDelete
We'll be praying for Carter.
Last week, we were freezing. Yesterday, it was in the 70s. Insane!ReplyDelete
I'll be thinking of and praying for you and Carter. I hope you find out what the problem is, get it resolved quickly, and get some sleep!
We're having Wummer! It was so humid when I went for a walk today, it felt like early summer!ReplyDelete
Hope the dr appt was okay.
This weather is freakin' crazy!ReplyDelete
I remember when Matt was up all night with his earache. TORTURE!! Praying....ReplyDelete
We've got a steady pouring of snow, and I love it :)ReplyDelete
I love the way you put that: wing or sprinter. So funny. It is really strange, though, isn't it?!?!? I hope you're getting a good night sleep soon. We've been feverish here, but better now. Oh, and HAPPY BIRTHDAY!!!!ReplyDelete
so do you live next door or what?ReplyDelete
Our weather is nuts too! 80 one day.... 45 the next!ReplyDelete
Hope he gets to feeling better and you get some sleep!
Snow all day today--tons!ReplyDelete
I'm just as confused as you are. WE had temps in the 60s and 70s, then thunderstorms! I'm scared what summer is going to be like!ReplyDelete
Poor Carter...just saw at Lori's that he has a perforated ear drum. Poor baby! I'm praying...ReplyDelete
Sorry to hear that your son is ill. Sprinter can do that.ReplyDelete
Hope he feels better soon.
p.s. I LOOVE your blog. :)
It's raining here but in the 60's! Our fig tree is starting to bud!!! I hope your little man heals quickly. Hopefully both of you will be ablt to get some rest!ReplyDelete
I just read at Lori's that poor Carter has a perforataed ear drum. Poor little man! Know that I'm praying for him.ReplyDelete
Weather is crazy around here, too. It was in the low 70s on Monday and Tuesday then in the 40s yesterday and 60s today. We are having Spring-like thunderstorms this week as well. Crazy!ReplyDelete
You know, I love warm weather...spring is my favorite season, but in the winter, i like it to be cold so i can appreciate spring more! Having said that, it has been pretty warm here in the DC area. Things got a little cooler today, but not January weather.ReplyDelete


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Oklahoma Tornado Relief
Jun 06, 2013 | News & Press
I'd like to thank SCE Federal Credit Union members and staff for their generous donations made to the American Red Cross' Disaster Relief Fund that is helping families affected by the recent tornadoes in Oklahoma. Through your donations of $4,920 and SCE FCU's matching donation of $5,000, a grand total of $9,920 is going toward food, shelter and other goods to help our fellow citizens. You're a wonderful example of the credit union "people helping people" motto and your selfless actions serve as a reminder that together we can do great things.
Sincerely yours,
Dennis J. Huber


text:
Top Definition
Line from the movie Face Off. Said by Nicholas Cage's character, Castor Troy. It means to perform oral sex on a female for, in this case, hours.
A guy trying to seduce a foxy lady: You know i could eat a peach for hours.
viết bởi Mitch Tyler 21 Tháng mười một, 2009
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Top Definition
Incredibly lazy, overweight person with a desire to eat foodstuffs of any kind (although commonly fatty) around the clock - and often does. A Jabba is also known to use a number of phrases associated with the trait, such as "Jabba so full of fat" or "NORTY JABBANA"
"Missy Elliot is a jabba"
"Lango you're such a jabba"
"Lango you're such a jabba"
লিখেছেন- Anonymous 19 de ফেব্রুয়ারি de 2003
Trending Now
Can you define these popular missing words?
A "Jabba" is in reference to "Jabba The Hut" from star wars. This fat, slobbish persn has little respect for their personal appearance and lacks the motivation to put out the minimal effort it takes to roll off of the couch. A slobish, obese brute. Can be found sleeping on the couch watching daytime tv with half eaten sandwiches on his gut. Sometime Jabbas are prone to smell of feces and filth from either defecating themselves or continuos farting.
When an unfamiliar friend stops by your house and ghasps, " What the fuck is that thing on the couch?" You can reply, "Oh that's just Jabba, he doesn't do much of anything, sorry about the smell though."
লিখেছেন- Dan Saathoff 27 de ডিসেম্বার de 2006
"Jabba the Hutt" was a character in the movie "Star Wars: Return of the Jedi". He was a giant, evil, obese slug-like creature.
The term is often used to describe someone who is fat and/or lazy.
The term is often used to describe someone who is fat and/or lazy.
That pimply comic-nerd looked like Jabba the Hutt.
Hey Jabba! Get off your lazy ass!
Hey Jabba! Get off your lazy ass!
লিখেছেন- Ten 18 de ফেব্রুয়ারি de 2005
(adj.) in a state of lethargic gluttony, induced by a sizable session of weed smoking (and subsequent munchies), that rivals the lustful, lethargic gluttony of Jabba the Hutt.
I was soo jabba last night-—I just laid there watching Half Baked and eating cans of Pringles.
লিখেছেন- natfatcat 23 de ডিসেম্বার de 2007
A term used to describe a vile, fat ugly man or woman.
Jabba love to gorge on food, and make strange noises when they guzzle there food
Jabba love to gorge on food, and make strange noises when they guzzle there food
"That Angel is such a Jabba"
লিখেছেন- Glenn Griffiths 24 de অগাস্ট de 2006
Cannabis Joint
Origination - liverpool
Origination - liverpool
roll a jabba steve im stressed out here.
লিখেছেন- Sir dingle dangle of berry 14 de মে de 2013
A term used in boxing derived from 'Jabber', it refers to someone steps into a ring who doesn't really know what they are doing, yet still seems to prevail, usually by luck or bending the rules.
"Yeah, you're not bad for a Jabba, but I don't think the world federation of boxing actually allow karate chops to the neck"
লিখেছেন- LupisJusticia 13 de ডিসেম্বার de 2009


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Serves 4 |
Prep Time 10 minutes |
Cook Time 25 minutes
15 ounces Eden Butter Beans, 1 can, do not drain
1 cup water
3 Tbsp Eden Bonito Flakes, crumbled, optional
1/4 cup onion, diced
1/4 cup carrots, diced
1/4 cup celery, diced
1/4 cup cabbage, chopped
1/4 tsp Eden Sea Salt
1 tsp Eden Shoyu Soy Sauce, or to taste
2 Tbsp scallions, finely chopped
Place all ingredients, except the shoyu and scallions, in a soup pot, cover and bring to a boil. Reduce the flame to medium-low, and simmer for 15 to 20 minutes. Reduce the flame to low, and add the shoyu. Simmer 3 to 4 more minutes. Serve, and garnish with scallions.
American, Beans, Condiments, Good/High Fiber, Good/High Protein, Japanese Food, Low Fat, Macrobiotic, No Sweetener Added, Soup, Chili & Stews


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Top Definition
To get intoxicated to the point where your overall demeanor is representative of a rabid dog.
Couldridge: Ahaha fck man miss you lot just wanna get maddogged and sink Swanny d
por motza 16 de Dezembro de 2013
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Can you define these popular missing words?
When someone has really embarassed you in public, preferably in school or at work. After insulting you (preferably by physical means), they stand over top of you or climb to a higher point than you and shout down at you, "you just got mad dogged!"
I ran over to Tom, tackled him from behind, and stood over him in front of all the Senior girls shouting, "YOU JUST GOT MAD DOGGED!" to which I promptly added.... "Bitch!"
por JR312 20 de Setembro de 2005
The act of getting stalked by someone you don't want to talk to, but they are persistent to the point you can't go anywhere until you have talk to them.
I tried to come over to your pad, but my neighbor Mad Dogged me into hearing about her latest ailment.
por jasonace 21 de Outubro de 2015


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Both Hunter and Wurth noted this is the second time Allentown residents unsuccessfully have followed the city charter to get a controversial new law passed.
In February, the county election board ruled that an initiative aimed at stopping the lease of the city's water and sewer operations would not appear on the May ballot because the more than 4,000 petition signatures had been collected late in 2012.
State law required that they had to be collected early this year, according to the election board.
If passed, that initiative would have allowed city residents to vote on selling or leasing any city asset worth more than $10 million.
DEP's role in decision
Fegley said this time the election board has left itself "very vulnerable to challenge, since they only justify their decision by saying that our Allentown clean air ordinance 'does not properly recognize and account for the Department of Environmental Protection's mandated approval role'."
Fegley argued: "There is no such mandated approval role since the ordinance does not purport to create nor constitute a program that would replace DEP's air regulatory role. The county {board}didn't really understand what they were doing."
Wurth said if voters think the proposed law would override DEP's authority and they don't want that to happen, they won't vote for it. He said if voters would vote for it, Delta Thermo or DEP could challenge it in court.
Wurth told council he was speaking on behalf of the Sierra Club, which supports both the proposed clean air ordinance "because it would improve the quality of air in Allentown" and for the rights of Allentown residents to have that ordinance placed on the ballot.
In late May, the city solicitor's office issued a legal opinion to City Council that the proposed clean air ordinance was fatally flawed.
Guridy reminded Fegley that council tabled any action on the proposed ordinance in June because it had just received a letter from a DEP attorney that indicated state law would supersede the proposed city law.
"That was only opinion, it was not fact," maintained Fegley. "The opinion left council unable to decide. So council basically said 'we'll let the citizens decide'. Therefore it goes immediately on the ballot. The board of elections is there to make sure it goes on the ballot properly."
O'Connell cast the only vote against tabling on June 19 because he wanted council to vote on the proposed ordinance. On Wednesday, O'Connell reminded Fegley that he supported the ordinance.
In the spring of 2012, City Council approved a 35-year-contract with Delta Thermo to build the plant, after packed public meetings and many hours of debate.
"I voted against the Delta Thermo project because it was totally unproven technology and environmentally unsound," said O'Connell in June. City Council member Jeanette Eichenwald, who joined O'Connell in voting against the Delta Thermo plant last year, was not at that June meeting.
Eichenwald also was not at Wednesday's meeting. She and council member Jeff Glazier were observing the Jewish holiday Rosh Hashanah.
Also during the meeting, city council hired a new police officer, Robert T. Busch of Annandale, N.J., at an annual salary of $46,856.


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Meet CSI: Crime Scene Investigation's latest guest star -- Justin Bieber.
The hair-flipping, Canadian pop sensation will make his acting debut on the CBS hit, following in the footsteps of Taylor Swift, who called her guest stint on the show "life-changing."
The 16-year-old will play "a troubled teen who is faced with a terrible decision regarding his only brother -- a decision that leads him into an explosive confrontation" with the crime scene investigators, the show's producers said in a statement on the show's Web site.
And the best part for Bieber fans? It's just the beginning. Producers said the episode is the start of "an emotional story that will conclude later in the season."
"This will be true event television," executive producers Carol Mendelsohn, Don McGill and Anthony Zuiker said. "We're looking forward to Justin's dramatic star turn, not only in the premiere, but in a continuing seasonal arc." … Alison Schwartz
Justin Bieber Will Be a Troubled Teen – on CSI


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Red Hot Chili Peppers Smartphone App for iPhone and Android
By Red Hot Chili Peppers News on January 17, 2012
The official Red Hot Chili Peppers Smartphone Application is now available to download for free! Not only do you get the latest Red Hot Chili Peppers news, tour dates, and more, but you also will get exclusive content! Behind the scenes video from the Look Around Music Video is currently available to watch exclusively through [...]
Posted in Other RHCP News, Red Hot Chili Peppers News | Tagged android, anthony kiedis, apple, chad smith, everly bear kiedis, flea, I'm With You, im with you tour, ipad, iphone, josh klinghoffer, look around, michael balzary, monarchy of roses, red hot chili peppers, rhcp, sandha khin, smartphone, the adventures of rain dance maggie, The Adventures Of Raindance Maggie, The Monarchy of Roses, tour | Leave a response


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Hydrogeologist: Wells won't go dry if water withdrawal center opens
July 18, 2013
Well water surrounding a proposed water withdrawal site in Old Lycoming Township will not be adversely impacted now or in the future, experts said Wednesday night....
So the gas industry hires a hydro-geologist Doug Cwienk, of GeoServices Ltd. to soothe the locals fear of losing their source of water. He then goes on to detail a formula that supposedly proves that there is more than enough water, personally I don't buy it. Hire an independent that hasn't been tainted by gas money rather than bringing in an individual who works for a company that does extensive work for the gas industry. Something smells on this one.
9 Agrees | 6 Disagrees | Report Abuse »
You are spot on Carl!...the township needs to hire their own "expert"....Traditionally..this township has folded under pressure...
6 Agrees | 6 Disagrees | Report Abuse »
Studies are good but they may or may not predict all the real world conditions that can occur, especially with recharge in drought or wet conditions. And if a dime from the gas companies is used to directly or indirectly pay for the study, some will not believe the results.
Maybe the best way to ensure no one loses their water supply is to consider supplemental water level monitors be installed or a separate monitoring well such that withdrawal rates could be reduced if static water levels start falling. The lower the static level, the lower the withdrawal rate.
3 Agrees | 2 Disagrees | Report Abuse »
Remember all these people's names so you can remember who it was who sold your kid's futures down the toilet.
6 Agrees | 6 Disagrees | Report Abuse »
As always, the gas industry brings some flunky in to sell the locals a bill of goods and then when their wells run dry the gas industry will say it wasn't because of them, just like Cabot ruining the wells in Dimmock and then saying, hey even though your wells were perfectly fine for the last 50 years, just because we moved into the area and now there is methane in your wells, it wasn't us....if the Township cared about its people, they would send this company packing!
5 Agrees | 8 Disagrees | Report Abuse »
In other news, the Devonian shale has been successfully fracked, providing a third shale layer of energy in our area, ensuring drilling will be here far beyond the lives of the anti-domestic energy liars.
6 Agrees | 6 Disagrees | Report Abuse »
Texas.. can you explain to me please what is "Waterless Fracking" that is being used in Texas now, I know that the industry has tried it in Wyoming.
2 Agrees | 0 Disagrees | Report Abuse »
What happened to the stepping stone to green renewable energies that this gas was suppose to bring. Instead we have Erik telling us drilling is here to stay. Looks like again we are we're told a line. Beware people in this area.
3 Agrees | 8 Disagrees | Report Abuse »
Texas another question for you. I have seen trailer mounted systems that are brought to the job sites to treat frack water so it can be reused again in Wyoming last year, which would save on water withdraw.
Why is that process not being used here?
2 Agrees | 0 Disagrees | Report Abuse »
waterless tracking is fairly new and unproven. The industry would love to use less or no water, so lots of R&D money is going into this.
GE just announced that they are getting involved and will research alternative tracking processes.
water is nearly 100% recycled here as well. Sometimes, it must be done off-site to handle the nastier salts and radioactive materials that Mother Earth gives to us from deep down.
we will have waterless tracking and/or 100% recycled water long before green energy becomes economically competitive with hydrocarbon sources.
4 Agrees | 1 Disagrees | Report Abuse »
It doesn't even need to be an issue of the wells "going dry". At my house, if the toilet flush valve hangs open and that little bit of water runs for like 12 hours, my water starts to get cloudy. And that's a whole lot less water than we're talking here. I am all for the gas industry being here, but we do need watchdogs to make them comply. And really, why would they even contemplate a well for this use in a residential/light comercial neighborhood in the first place. Get your water elsewhere.
2 Agrees | 1 Disagrees | Report Abuse »
I keep losing my internet service, thank you Erik for answering my questions.
1 Agrees | 1 Disagrees | Report Abuse »
Born here, we have been doing that here for quite some time. Most companies try to recycle/reuse all their flowback. Many are now doing it right on the frac. It's cost effective to filter onsite and reuse it, rather then transporting it to a third party location for filtering only to have to pick it up and deliver to a frac later
1 Agrees | 0 Disagrees | Report Abuse »
The antis use outdated information to create fear.
Advancements in drilling are accelerating.
I am fascinated with the use of steam in old, dry wells to release additional oil. It has brought new life to old wells.
0 Agrees | 1 Disagrees | Report Abuse »
"can you explain to me please what is "Waterless Fracking" that is being used" --BornHere
Sorry for the late reply; I don't leave work until 7 CDT. I don't have any first hand knowledge with it but what I have read is that the use propane/butane instead of water to carry the sand. I would suspect there are some challenges with somehow increasing the viscosity to carry the sand so it doesn't settle out too easily and it has to be stored under pressure on the surface.
At one of my former employers, we fracked some wells with what we called a condensate-emulsion in the late 70's. We used condensate that was produced from gas wells; it is a little higher molecular weight than the propane/butane mixture. Even though these fracs achieved higher production rates, we felt that the potential fire or explosion that could result was not worth the risk to the people on location operating the frac equipment.
0 Agrees | 0 Disagrees | Report Abuse »
BornHere, looks like Erik answered your question on the water treating.
0 Agrees | 0 Disagrees | Report Abuse »
Thanks Texas.
0 Agrees | 0 Disagrees | Report Abuse »
Yes we are still remembering names of those past like a lady named bloom who has done nothing but ruin our kids life's long before big gas got here
0 Agrees | 0 Disagrees | Report Abuse »
Come to the Pine Creek valley is you want to see exactly what the gas industry is doing to our beautiful area..and erik...really water recycling, then why can I count 40+ water trucks at any given time in a row on the creek road?
0 Agrees | 0 Disagrees | Report Abuse »
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|Protein Bridges DNA Base and Nucleotide Excision Repair Pathways
Alkyltransferase proteins (AGT) protect cells from the biological effects of DNA damage caused by the addition of alkyl groups (alkylation). Alkyltransferase-like proteins (ATLs) can do the same, but they lack the reactive cysteine residue that allows the alkyltransferase function, and the mechanism for cell protection has remained unknown. To address this mystery, a British–American team lead by researchers at the Scripps Research Institute recently applied a combination of x-ray structural, biochemical, and genetic studies to ATLs in the yeast Schizosaccharomyces pombe without and with damaged DNA. By showing how a process called non-enzymatic nucleotide flipping activates ATL-initiated DNA repair, their results may improve our understanding of genomic integrity and responses to DNA damage relevant to pathogens and cancer development.
The research team started with diffraction data collected at the ALS (SIBYLS Beamline 12.3.1) and SSRL to determine structures for ATL (Atl1) without damage and with either endogenous or cigarette-smoke-derived damage. These structures, the first for any ATL, show that although Atl1 looks similar to the parts of alkyltransferase (AGT) where DNA binding and alkyl transfer occur, it has certain distinguishing features. Like AGT, Atl1 flips (transfers) a nucleotide from the DNA double helix to its active site to access damaged nucleotides. But unlike AGT and most other known DNA nucleotide-flipping proteins, this flipping is not connected to any type of enzymatic activity or catalysis. In addition, Atl1 has a larger binding pocket to accommodate a wider variety of damaged DNA nucleotides, including those that are too big to fit the AGT binding pocket, and Atl1 creates a bigger bend in DNA than AGT upon binding DNA.
Typically, there are two general DNA repair mechanisms for DNA alkylation damage, direct damage reversal and base excision repair (BER). For example, base alkylation damage is repaired by direct damage reversal proteins like AGT or by lesion-specific DNA enzymes (glycosylases) that initiate the BER pathway by excising bases. In contrast, there is another, more versatile DNA repair pathway called nucleotide excision repair (NER) that works by removing bulkier DNA helix-distorting lesions by excising a DNA patch containing a damaged base. Generally, NER poorly recognizes the kinds of alkylation damage repaired by alkyltransferases and is therefore not usually expected to be active in these cases.
Through a series of genetic and biochemical experiments, however, the researchers unexpectedly discovered that Atl1 function is linked to the NER pathway of DNA repair after all. It turns out that ATL bridges two DNA repair pathways (base repair and nucleotide excision repair) that were previously thought to function independently of each other. The researchers' combined results reveal a general mechanism in which ATL binds weakly distorting lesions (base damage) in a manner comparable to AGT and BER glycosylases and recruits NER-associated proteins by sculpting the weakly distorting alkylation damage into a bulky lesion that is channeled into the NER pathway.
By mapping conservation of amino acid sequences between their ATL and sequences in other ATLs, the researchers realized that their structures could also characterize the other ATLs. Analysis of lesion-binding site conservation based on the new structures led to identification of new ATLs in ancestral archaea (unicellular microorganisms without nuclei or organelles) as well as the first ATL discovered in any multicellular organism, a sea anemone. Together with already known ATLs, this discovery indicates that ATL interactions are ancestral to present-day repair pathways in all domains of life. Therefore, although no ATL has yet been discovered in humans, it is likely that an ATL or similar protein exists in humans, thereby opening the door to improved cancer chemotherapy based on alkylating agents and repair pathway control.
Research funding: National Institutes of Heath, The Skaggs Institute for Chemical Biology, North West Cancer Research Fund, Cancer Research-UK and CHEMORES. Operation of the ALS and of SSRL is supported by the U.S. Department of Energy, Office of Basic Energy Sciences.
Publication about this research: J.L. Tubbs, V. Latypov, S. Kanugula, A. Butt, M. Melikishvili, R. Kraehenbuehl, O. Fleck, A. Marriott, A.J. Watson, B. Verbeek, G. McGown, M. Thorncroft, M.F. Santibanez-Koref, C. Millington, A.S. Arvai, M.D. Kroeger, L.A. Peterson, D.M. Williams, M.G. Fried, G.P. Margison, A.E. Pegg, and J.A. Tainer, "Flipping of alkylated DNA damage bridges base and nucleotide excision repair." Nature 459, 808 (2009).


text:
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2011: Second Team All-Atlantic Sun...A-Sun Player of the Week (Oct. 31)...College Soccer 360 National Team of the Week (Oct. 31)...College Soccer News National Team of the Week (Oct. 31)...A-Sun Conference Scholar...appeared in 17 matches with 15 starts...scored four goals and ranked second on the team with six assists for 14 points...made two National Teams of the Week and picked up the A-Sun Player of the Week award at the end of October with a game-tying goal against #9 UCF (Oct. 25) and a pair of goals, including the game-winning score in overtime, to beat Jacksonville 4-3 on the road (Oct. 30)...also scored against FGCU (Sept. 30)...two assists in season-opening win over Florida Tech (Aug. 27) and in Oct. 3 win over Lipscomb...assisted on Ryan Asare-Bediako's OT winner to beat Mercer 1-0 (Oct. 9) and in Nov. 5 win over Nebraska-Omaha.
2010: Atlantic Sun All-Academic Team...enjoyed breakout season with five goals and four assists...tied for second on the team in goals and fifth in assists...two goals and an assist in win over Johnson & Wales (Sept. 10)...goal in win over Manhattan (Sept. 17)...scored in win over ETSU (Oct. 8) and at Campbell (Oct. 16).
2009: Came off the bench in 12 games as a freshman... Picked up his first career assist on the winning goal in Stetson's 5-1 victory over Lipscomb (10/9)... Had a season-high two shots, both on goal in 4-2 win at Jacksonville (10/2)... Averaged 0.42 shots per game.
High School: Graduated from West Springfield High School in Springfield, Virginia... Earned three varsity letters as a member of the Spartans soccer team... He earned All-District and All-Region honors... Named Second Team All-Met by the Washington Post in 2007... Played two seasons for the U19 squad at Stevenage Borough in United Kingdom after being spotted playing for Chelsea USA in the AVC International Cup in Sportilia, Italy.
Personal: Son of Don and Eva Eckenrode of Springfield, Virginia... Born December 5, 1989 in Silver Springs, Maryland... Majoring in Communication Studies.
Eckenrode's Career Statistics


text:
Top Definition
3, biggdy bam
2, bad ass mouther fucker
3, biggdy bam
wow he is a phil
от TEbs 27 май 2003
Trending Now
Can you define these popular missing words?
Complete, absolute perfection. Nothing in the world that is better. Heaven.
"God, You're just so phill"
от lex 26 септември 2004
someone who accuses girls of being crack whores
"I hate when I he calls me a crack whore, he is such a phill"
от Kat 15 май 2003
P'Hill is the abbreviation for Pleasant Hill Road, Gwinnett County, Georgia. Pleasant Hill Road is a major road and shopping-entertainment district that runs through the center or "downtown" of Gwinnett County, Georgia.
I went to Super H Mart on P'Hill and bought freshly made tofu and kimchi.
от Pleasant Hill Road 17 юли 2008
A nickname for the cheap but amazing Phillips Vodka. Often consumed with Mountain Dew. Its essential that before taking a shot of P Hills with someone that you cheers and say "Happy P Hills!"
Give me some fuckin P Hills.
от Raaaaaaaaaaaaaaaaaackem 23 ноември 2010
n. an awesome boyfriend; mestre at capoeira (hehe); tHe OnLy GuY tHaT i'LL eVeR LoVe ThIs mUcH; the one who will always have my love, no matter what.
pHiLL does not need to question raCheL's love for him.
от pHiLL, meu amor 07 февруари 2005
Verb. To phill is to listen to the band Nickleback on ones Macbook.
Wow! What a loser, he's totally philling right now
от anonymous_asdf 08 май 2011


text:
great twist at the end.
wonderful writing.
A really great original story which, although it uses JKR's characters, seems to reinvent each of them. I've seen Bill in a new light and hope to read more of your fics soon!
Author's Response: Thank you so much for your review! :)
So. Very. Good. Kara, this story was great--the presence of a curse after all was a great touch, and I love the surprise (at least for me) that Natasha was a thief! I was beginning to think Marcus was involved in some way, but you really got me with Natasha. One of the real strengths here is the detail you've created in this world of curse-breaking, and the overwhelming presence of magic in the story. Loved how much the characters relied upon it... though far from Hogwarts, this was just so very magical and so very Harry Potter. LOVE. The canon tie-in at the end is perhaps my favorite of all the fabulous small touches... what a brilliant way to ground this fic and this curse-breaking universe you've created into Harry's known world. Really, really enjoyed this, Kara.
Author's Response: LORI! I can't believe I hadn't replied to this yet!! Thank you so so much for reading the story and reviewing. I'm always a bit stunned when people like you like a fic of mine, hahaha, so this keeps making my days! Thank you so much.
Karaaaaaaa. :) Hello there. Seems I've been sucked into the vortex that is your author page, but I don't mind it a bit. I'm enjoying this a lot, halfway through now, and so impressed with the curse-breaking world you've imagined here. Such attention to detail and layers of mystery and questions... it's fab! I love your Bill almost as much as your Charlie, and there are still six chapters for me to read! Just really hooked on your storytelling, Kara. Good stuff. I hope to finish in the next day or so.
This was a great mystery. Action packed, emotion packed and secret packed. :)
I loved it..
Somehow I though that Marcus would be involved.. without any logical deduction though... you have kept the story interesting till the end.. I thoroghly enjoyed it...Thank you so much..
-- Aaicha
Author's Response: Thank you very much for reading and taking the time to review! :) I'm very glad you enjoyed it. I suppose there was something shifty about Marcus's character all along, wasn't there? It's great to know that you think the story was interesting till the end... nothing worse than dropping to a boring point before the big reveal!
Again, thank you a lot for this review. It means so much to me.
What a fabulous mystery! You have definitely had me on a leash ha ha ha. I should have picked up something when I read the convo with Pilliwickle in the last chapter. But I'm happy I was wrong about most things :D
Now, I need to know what the secret is and pester you to write the next one!
Author's Response: Thank youuuu for all the reviews. You know what the secret is now.... But it'll be a while before the next Bill story, sadly. Thanks again, and mucho love!
Though, what did Mahon have to do with it? Did he see something? Or was it part of the curse ruse?
What does Marcus have to do with this???
Author's Response: eeeeek. Deverill and Pilliwickle... That would have been an interesting combo. WHAT exactly would they have been in though? hahaha. Glad I could lead you on for a brief while...
Interesting character. Very interesting.
Now, why the hell don't wizards check for fingerprint? >.>
I want to know what Pilliwickle ha to say.
Author's Response: You know the thing about fingerprints is... As soon as they became very popular as a method, mystery writers found a way around them. So in Agatha Christie's books, Poirot always waved the idea of checking for them off, arguing that any criminal with an ounce of cleverness would have worn gloves. I doubt wizards ever checked for fingerprints in the first place, since there's a lot you can do with a well aimed Wingardium Leviosaaaaa, if Ron can whack the troll on the head in his first year. Thank youuuuu for the review!
Wouldn't it be glorious if Stadwell was behind this? Haha!
Okay, motive. Motive. Motive.
I keep thinking Marcus because he's the only one with obvious benefits. What if this curse thing he's working up is a ruse? What if the people really believed the curse is there and abandons the tomb? All that gold!
(Oh, I really don't know how it works, though. If there's a curse on the treasure, are they abandoned? Or do the goblins take them anyway?)
Am I focussing only on the gold as a motive?
Are Deverill and Natasha together?
Author's Response: If there's a curse, it has to be broken. If it can't be broken, I'm thinking it might be taken to a sort of research facility with specialists. Someone like Bill wouldn't leave a curse lying around for anyone to stumble across, and the goblins wouldn't leave the gold lying around.
How does Marcus benefit though?
Well, Chubbs was a red herring. :O
This was such a spine-chilling chapter, though! I mean, the suspense was so bloody thick. Ha. Pun.
Okay, Marcus. What if this is set up to look like a curse? Did he really see a shadow pass near the sarcophagus?
Author's Response: I wrote this at uni and got myself into quite the panic while writing... This is also the first part I wrote of this story. I'm really pleased that it seems to create some semblance of suspense, because I was so desperately going for that. Thank you :-*
I need to reprocess my thoughts.
Is Natasha involved?
What's the connection between Althea and Deverill?
Is the attack on Pilliwickle staged? If so, why?
Is Marcus genuinely paranoid or is this an act?
Questions, questions.
Author's Response: Answers shall follow! Love you for doing this love love
The smut has got me all hot and bothered, but OMP! Mahon's dead!
I don't want Natasha to be evil.
BUT I don't want to suspect Althea either because that is so obvious :/
Author's Response: EEEK reaching territory of stuff you haven't read yet now! AAAAH... Well how COULD Natasha have done anything while she was doing the nasty with Bill...
WHOAAAA! So many things happening!
Okay, Chubbs gets more suspicious with each word written about her, and Papadoulopos seems like one of those "as long as you're bringing the gold in, I'll be laughing" characters. It's, of course, too early to make any concrete judgments.
Right now, I can't help but feel that something bad is going to happen to Marcus D:
But before that, some sexin', eh?
Author's Response: Eeeeeek.... Yeah, you've got Papadopoulus about right. He's cool with everyone as long as all the gold is there in the end.
When I read your draft, this was my favourite section.
It still is.
I am so envious of how you've written Bill's work. I've always wanted to it myself, but I just never had enough imagination (or the will to research). It was so exciting to read all this.
Author's Response: Well you have written about Bill's work, though, haven't you.... albeit in a slightly different manner. Thank you thank you thank youuuuuu for all the reviewing!
The plot thickens!
What I find most impressive is the amount of detail you've put into this line of profession. The goblins' unflinching scrutiny, the curses, the distribution of fees. They could easily be canon.
I need to know what's up with poor Marcus.
Author's Response: Eeek thank you. All of that wasn't even in my original plan but felt reasonable as I was writing. It's a totally fascinating profession, isn't it? I want to do iiiiit!
Follow thislink quietly if you value your life:
Author's Response: I was truly hoping that this would lead to me finally being recruited for a secret service...
First chapter in. It's as good as the first time I read it. :D I love the sense of adventure that has already set in. Who's Chubbs and what's her real goal? Is Natasha good or evil? Must read on to find out more!
Author's Response: OMP it has begun :x can't wait for more reviews /greedygreedo. Love love love you. Thanks for taking the tiiiiiime!
Finally, I get a moment to myself and can read this properly. Thank you for such a splendid story. You're so good at mysteries and this was so intriguing.
I didn't work out who it was, and am kicking myself because the clues were there, but I did suspect Natasha and had an inkling about the artefacts, mainly because it was her word only and also - unless she died - we have prior knowledge of Bill and Fleur, so I knew it couldn;t work out. I was totally fooled by the fact that she and Marcus were in it together, although when they were working togetehr on the sandstorm I did start to wonder.
I didn't want it to be Marcus, and that's a strength, my Karador, because I cared about him. I cared about an OC you created and the fact that he was Bill's friend *sigh*. Natasha ... hmmm, well, I like Fleur, so obviously I'm going to twitch a little at any woman who gets their wicked way with him, but I did love the character and was very impressed at the clear way you wrote her. She was easy to picture and the final scenes when she's spilling everything were written so very well.
I do hope you write more Bill mysteries. (There could be a witch he meets who is good but they part because um ... I ... I mean she ... I'll leave it up to you, but she's quite short and with mad hair - hee hee.)
I can't review very well, but just so you know, I really did enjoy reading this and it's not because you're a flister, it's because it's a bloody good story and very different from the usual fanfic.
Blooming brilliant. Well done, Karador, just ... well done. *sigh* ~Carole~
Author's Response: Carooooooooooooooooooole
How do I reply... uhm. OH well, I think I remember you saying a while ago that you suspected Marcus (when I hadn't posted yet but you betaed for me) and that threw a bit of a stick between my legs because I thought -- damn, she's already figured it out. I considered changing it all, but then decided to just run with it, and work harder to still have it be a surprise in the end. His motives were part of the mystery, as they always are, because even if he had means and opportunity, as long as he isn't a psychopath, he'll need a motive too.
Natasha wasn't meant to be evil when I started planning, but after a while she just screamed art thief to me, and so that was her. And it just made a lot of sense that Marcus would be a person who can be talked into that sort of thing because he's so worried about his financial situation and it seems like a safe thing really.
Oh dear Carole, Bill's next... adventure has been planned weeks ago. Just wait and see -- hahaha. It's all planned out. And I do love all of your reviews, so they're brilliant no matter what you say! HA.
thank you so much for all your help and encouragement and everything you've given me while I was writing this and fretting.
OK, now I've finished and I think it was very good.
I had suspected Marcus from the start, though not for the motives you gave him, but Natasha being an art thief (my favorite kind of thief, BTW) was a complete surprise. The emotion-heightening curse was ingenious and the effects nicely described in the early chapters.
All-in-all a nice piece of work.
(Now I'm off to your author page to see what else you've written)
Author's Response: Thank you very much for reading it all and reviewing! The motives were part of the mystery, because really, he was behaving too oddly not to be suspicious. I do love art thiefs too -- they're so wonderfully glamorous somehow. They know about art and its worth and are still devious enough to steal it. I might write about an actual art heist some day, because I think there are just too many possibilities not to explore one or two of them...
I'm very glad that you liked this story. I hope my author's page isn't too disappointing -- I took a bit of a break from writing for a while, so there are a lot of stories that are still unfinished. I will get back to most of them some day, but I've been sucked up in this mystery thing lately, so I'll probably write one or two new stories before returning to the old ones. I really hope you'll be back when I submit something new though, and not put off by the out-of-date-ness of my author's page!
Thanks again. I really appreciate the reviews!


text:
A term (noun or adjective) to describe someone who too closely follows the 'gay stereotype.'
Usually used amongst super-christians.
Usually used amongst super-christians.
The homogays are staging capchta images to convert our children.
dodane przez Gatodo maj 11, 2011
Trending Now
Can you define these popular missing words?
Top Definition
The step beyond gay. A man that has taken time to go out of his way to make sure u know he's gay. This term doen't apply to women because lesbians rule... sept if they're butch and goss
"Holy crap look at that dude's scarf and pink button-down shirt thats open at the top. He's so homogay"
dodane przez Taildrag wrzesień 20, 2005
when something is more gay than gay. thus, makes it homo gay.
"Hawthorne High School is homo gay."
dodane przez pedro luty 16, 2005
extremely gay, therefore just about as gay as it gets.
Woah my friend, you ARE the homogay.
dodane przez Molly Williams marzec 03, 2003
Very gay person.
Jonny is very homogay.
dodane przez jonny marzec 11, 2003
used on SNL (saturday night live) by mango meaning just gay...probably could be used as super ultra uber gay
"Why does everyone think I'm the homo gay?"
-Mango (Chris Kattan)
-Mango (Chris Kattan)
dodane przez the homo gay marzec 12, 2005
The splicing of "homosexual" and its more common synonym, "gay". Saying "homogay" takes off two syllables that would otherwise need to be said in saying "homosexual". Semi-formal way of saying "gay".
He is homogay. (ho-mo-gay instead of ho-mo-sex-u-al)
dodane przez SamusAX grudzień 11, 2004


text:
Great Decor in a Flash Without a Lot of Cash
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Antiqued and Textured Frame
By: DecoArt
We are adding the craft to your Craft Projects.
The project was added to your Craft Projects.
Click here to view your Craft Projects.
Combine the old and the new with this antiqued, textured frame with optional textured wallpaper insert.
- DecoArt Americana Brushes DBF2575-B - Flat 3/4"
- DecoArt Elegant Finish Glazes DGM03 - Medieval Gold
- DecoArt Elegant Finish Metallics DA249 - Silver Sage
- DecoArt Dazzling Metallics DAO74 - Royal Ruby
- DecoArt Palette Knife DT02 - Palette Knife
- DecoArt Texture Terra Cotta TXT03 - Grand Canyon
- DecoArt Texture Crackle TXC02 - Neutral
- Water container
- Palette or plastic plate
- Paper towels
- Wood frame
- Textured wallpaper, optional
Use palette knife to randomly apply Texture Terra Cotta Grand Canyon on frame surface.
Use palette knife to apply Texture Neutral Crackle in open areas, dragging crackle just over edges of Grand Canyon Terra Cotta. Let dry.
Use brush to apply Medieval Gold glaze lightly over frame. Immediately wipe back with slightly dampened paper towel or soft cloth.
- For optional framed, textured wallpaper:
Cut textured wallpaper to fit inside frame opening.
Basecoat wallpaper Royal Ruby. Let dry.
- Use brush to apply Silver Sage. Immediately wipe back with paper towel.
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Apr 12, 2010
Where did the piece in the middle come from? That's beautiful.
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text:
Min comment interval:
Remaining character count: 8192
Remaining character count: 8192
Shortcuts: "C" opens comments. "R" refreshes comments.
Record voice message?
Return to bug reports Leave a comment Refresh Comments (6569)
Anonymous comments allowed.
2 new threads. 1 new replies.
#15 - psychadelicace (05/18/2014) [-]
I have had 4 OC that have reached 1000+ thumbs and im not receiving OC colour changer item
#13 - betweenburiedandme (05/17/2014) [-]
anons can comment every 15 seconds
on this account i can only comment every minute
on this account i can only comment every minute
#14 to #13 - givememoarpony (05/18/2014) [-]
i think that's something admin's implementing on level 0 accounts. accounts below -100 can only comment every 60 minutes across different accounts.
#12 - stutterguy (05/16/2014) [-]
Sometimes when I click 'Next' it takes me to some of my old content instead of the next post on the front page.
I couldn't really screen cap it.
I couldn't really screen cap it.
#11 - garymotherfingoak (05/15/2014) [-]
I'm pretty sure we're all having the image loading issue, you can shut up about it now.
#10 - nosurprise ONLINE (05/15/2014) [-]
No images on boards are loading unless i click on the image. When I post a comment all the images load but when I refresh all the images don't load again. My internet is fine too
#9 - enteroreninenine (05/15/2014) [-]
pressing c to comment doesn;t work on the pone board
it works everywhere else
idk if you did that on purpose tho
it works everywhere else
idk if you did that on purpose tho
#8 - krogeryogurt (05/15/2014) [-]
trying to edit my pic and it says content editing disabled fro 30 minutes.. its been Hours!!!
#7 - bruinslover (05/15/2014) [-]
ever since this latest users thing came along, the boards have been acting funny. get rid of it please.
#6 - onlyonehotspur (05/15/2014) [-]
funnyjunk.com/user_pictures/voiceofredemption/4892317/Friendly/ I can't make a comment here and the comment pictures are not showing
#3 - kiratheunholy (05/15/2014) [-]
"Latest users" breaks when you press r to refresh the comments on the page. Here is a gif showing it.
#4 to #3 - kiratheunholy (05/15/2014) [-]
Incase FJ made that gif too small to see: You need to login to view this link
#2 - ktom (05/15/2014) [-]
clicking "more" in the latest users box always yields "request failed"
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text:
You might say she was destined to be a volleyball player.
With four aunts who played collegiately and a mother and grandmother who played recreationally, Stetson University junior Erika White was immersed in the sport from day one.
"When most kids are born they have rattles or other toys like that, but I'm pretty sure some of the first toys I got were those little promotional volleyballs some teams throw out to fans before games," White said.
A native of the small central Illinois town of Jacksonville, White says her aunts were the ones that really sparked her interest in the sport at a young age.
"I remember having big family get-togethers where we would all be messing around in the backyard and there would always be a volleyball there," White said. "We even got into trouble playing inside my grandma's house a few times but she was usually playing with us so she didn't mind."
White's four aunts are all on her father's side and all played volleyball in college: Michelle Aring at Florida Tech, Jenn Pool at Northern Illinois, and Donna May and Candy West at Illinois College. White's father, Randall, was the eldest child and the lone son in the family and he, too, was an athlete, though he competed in baseball and basketball.
White said her aunts weren't blessed with an abundance of height, but they taught her how to be a valuable contributor in various facets of the game. She made strong use of those skills in high school where she played both setter and middle blocker. And when White and her younger sister, Rachel, were in action for Routt Catholic High, they certainly had plenty of support in the crowd.
"I always joked that I never just had a few fans at the game, I had a whole cheering section there for my sister and me," White said. "My dad would even paint his head with my number and the team's name and wear matching warm-ups."
Now that White is playing for Stetson, it is a little more difficult for her family to attend games en masse. Instead, her parents will often connect the computer to the big screen TV and gather the family to watch the live video stream on the internet.
Another viewing party will likely be on tap this weekend as the Hatters (1-3) host the Stetson Westin Classic at the Edmunds Center. Stetson will play Savannah State twice as well as Providence and Bethune-Cookman during the two-day tournament, which starts Friday at 3 p.m.
The Hatters are looking to build off a strong start last weekend at the UniWyo Invitational. Stetson opened the season with a thrilling 3-1 victory over Drake, a match in which White had a direct impact on the outcome. With the Hatters leading 2-1 and the score tied at 23 in the fourth set, White put down back-to-back kills to give Stetson's its first season-opening win since 2004.
"It felt great to put those balls away, but the serve receivers and defense played spectacular all weekend," White said. "They gave both (setters) Kayla and Danika great passes allowing them to make quality sets to the hitters. Overall, it felt amazing to be out there on the floor again with all my teammates, stepping into a gym where we have never played before and really all of us showing off all the hard work we have been putting in this preseason and how far we have come."
Both White and Loesch said that the season playing sand volleyball has had a tremendous positive affect on her her indoor game.
"Erika has really improved her blocking and her attacking," Loesch said. "She got some good experience playing sand and worked hard on her conditioning over the summer. She has really improved her vertical and her foot speed as well as her skill. She has worked really hard to be a contributor and we are glad she has. The great thing about her is that in our drills all through the preseason, when it was clutch time, Erika always came through with a big kill or a block."
White has already compiled 29 kills in four matches, seven more than she had in her first two seasons combined. However, she is not focused on those stats; she is just looking forward to having the team playing back at the Edmunds Center this weekend."
"Overall, we learned some things we need to improve on (in Wyoming) but we can't wait to see the crowds we get this weekend," White said. "We want to show off this year's team and we are prepared to defend our home court."
General Admission full day passes for each day of the tournament are $15 for adults and $12 for seniors and students. All home volleyball matches are free to Stetson students, faculty, and staff with a Stetson University ID. For more information call (386) 738-HATS.
For fans who cannot make it to the games, the four Stetson matches will be streamed live on HatterVision. There will also be live stats available at GoHatters.com, as well as updates through the @StetsonVB twitter feed and the Hat-Alerts text messaging service.
Friday, September 6
3 pm - Savannah State at Stetson
5 pm - Providence at Savannah State
7 pm - Bethune-Cookman at Stetson
Saturday, September 7
9 am - Savannah State vs. Bethune-Cookman
11 am - Providence at Stetson
1 pm - Bethune-Cookman vs. Providence
3 pm - Savannah State at Stetson


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That is a very nice Murano. I do wish I could find a book on identifying Murano paperweight makers.
The process will also involve collecting examples of the different makers. Oh dear, isn't that a shame?
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Top Definition
A drink invented by Mr Arrigo Cipriani at Harry's Bar in Venice, Italy. It is made of fresh peach juice and prosecco wine. It is served cold.
When in Venice, I always have a cold bellini.
de The Peach 26 Iulie 2005
Trending Now
Can you define these popular missing words?
Borne out of Brooklyn life, it refers to the "big job", the one final heist that will let a common crook retire forever.
Jim's got a bellini that bigger than anything you've ever done.
I want in on Jim's bellini.
I want in on Jim's bellini.
de Theodore 17 Mai 2004
The word exclaimed when a particular individual in a group makes shit banter whilst trying to be one of the lads. A vertical arm sweep/cutting motion is made at the same time, in order to portray a separation or screen between the person who made shit banter and the person calling "bellini".
Danny: "lads you seen the tits on mrs roberts? she may be a cow but I would milk those udders, know what I mean?!!"
Member of "lads": "Bellini".
Initial conversation continues.
Member of "lads": "Bellini".
Initial conversation continues.
de jarry999 01 Februarie 2012
A sorry mother fucker who thinks the world is going to come to an end
Joe your such a bellini about things
de Anonymous 24 Octombrie 2003


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It's time for the first major awards show of the season: the Golden Globe Awards! WillBreaking Bad or The Big Bang Theory win its first series Globe? Can Amy Poehler parlay her co-hosting gig into a win? And will Meryl Streep win a record ninth statuette?TVGuide.com's Golden Globes predictionsSound off below with your picks!
View original Golden Globes: Who Do You Want to Win? at TVGuide.com
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Location, ST | website.com


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Memorial Day: A history in pictures
POSTED: 9:15 AM PDT May 24, 2012 UPDATED: 9:34 PM PDT May 29, 2016
As you wrap up the holiday weekend, look back at the history of Memorial Day through old and new images.
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