text:
Retro Pin Art is a classic office toy that lets you create a 3D impression of whatever tickles your fancy into a set of blunt pins.
Popular in the '80s, this Pin Art case will make a fun addition to any desktop. Be as creative as you like and there'll never be another dull moment in your office again. - L.M.
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(40 Reviews)
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Retro Pin Art is a great purchase and truly addictive.
Hi, I've just bought the retro pin art for my 75 year old cousin Jack's birthday! We've had one ourselves for many years and have had endless fun with it. It still looks as good as new, too. I can't imagine it could ever wear out. Jack was a bit bemused at first but soon got the hang of it as it was passed around the guests at his party, who found things to do with it that even we hadn't! Anyone buying this for themselves or as a gift won't be disappointed.
Loved the Retro Pin Art as a kid and was so happy to find it again, that happy that I bought myself one and my kids one each! We've all had so much fun playing with them!
Product does not come sealed, although does come wrapped up. Product is smaller than anticipated but does look good. Pins, however, are a bit loose. Overall though, a good looking product.
The Retro Pin Art pin set I got is performing below expectations, as a few nails were bent and the overall condition of the pins feels very cheapish. The acrylic glass was scratched giving it an appearance that the whole product had been used by someone before for a while and then re-packaged. I played with one of this many years ago and the pins were staying in position more tightly (tighter tolerances). In this instance today, the pins move very freely and it is harder to keep a shape in my opinion.
The Retro Pin Art is a great item and my son loves it. It is good quality, a must for kids!
Freaking Awesome!
I bought the Retro Pin Art for my 11 year old son's Christmas and it was the best value gift I have purchased for him, he loves it! He plays with it daily and brings it out to entertain his friends who all want one too.
A good product. Love these things - they're fun and look cool with a shape in them on the shelf. This one works fine and seems to be good quality. I would recommend
I just love this Retro Pin Art. It takes me back to my youth... were I spent the day hunting around for things to push into it. Tip - don't use soft fruit!
The Retro Pin Art is a really cool thing. The other reviews have said that it was quite small but I found that it was a really good size! (about the size of a hand, with space to spread your fingers out).
I bought this Retro Pin Art as a present and the family member loved it.
The Retro Pin Art is an excellent product. It gives hours of pleasure that you never tire of and you can create something new all the time.
The Retro Pin Art is an excellent toy. Was played with a lot and despite my son getting one of the pins stuck up his nose! It's being played with as I write.
The Retro Pin Art is a classic gift but not as remembered, as the pins don't stay when you hold it up.
My kids loved the Retro Pin Art. Of all their presents this one was played with the most.
I love the Retro Pin Art. I remember it from my childhood, hours of fun. Bought as gifts for varying age groups, all were gratefully received.
I purchased this as a Christmas present for my 6 year old nephew, I had one when I was younger; however, I'm not sure whether it was more for him or me!!! Really great gift.
The kids are having a great time with it.
This Retro Pin Art is really good. I've not stopped using it but it's not as big as I thought although I still like it!
The Retro Pin Art is an excellent little gift for someone with a funny sense of humour! Cheap and cheerful!
Pretty cool, you get what you see and it works, however pins are quite loose so your "form" might easily "break" or simply move and change
Excellent, lots of fun, funny things to pin art
Cannot wait to give my kids the Retro Pin Art for Christmas. I loved mine when I was younger, hope they have as much fun as I did. Thank you IWOOT.
Adults and children love the Retro Pin Art, it's completely fascinating and holds it shape brilliantly so almost doubles as a work of art!
Bought as a gift for a hard-to-buy-for in-law who loved it and said they'd always wanted one! Couple of pins a bit lazy to perform properly at first, hence one star off.
I had one of these as a child; my brother and I played with it for hours. It's great to be able to now buy one for my son. Though I bet it's my brother and I that will be fighting over it on Christmas day!
I bought two of the Retro Pin Arts, one for me and one for Christmas for a family member. I've always wanted one and I'm very happy with the purchase!
Such a simple idea but actually loads of fun. Even the youngest of kids love it because they can't get their heads around how it works. You can leave it standing afterwards with a cute cherub in it or something funny. Great little gift.
Hope the Retro Pin Art will be a popular nostalgic present!
The Retro Pin Art is absolutely brilliant. I got one for my daughter but adults have spent more time playing with it than the kids. Plus they look great on the side with a funky print left on it. Totally recommend these for any age.
I have always wanted a Retro Pin Art for myself, sadly I was never given one for either birthdays or christmas. This year my youngest daughter wrote this down on her Birthday list and how could I refuse. It arrived at work and I just had to see if I could have a go before she got it for her birthday. I carefully opened the box and left no indents, but the pins were neatly kept level with a white piece of card which would easily let you know it had been moved... so sadly I had to wait for days! Once opened, my daughter was playing with it and making all sorts of different pieces of art, and eventually so was I. You are only limited by your imagination as to what you can do with this. We have placed ours in the living room and you have to pass it on the way to the kitchen, so the ever changing artwork is good to admire.
Bought this Retro Pin Art as a gift for an eight year old but it has brought entertainment to all her family. It fires the imagination as we try to find who can produce the most original work of art. The television is obsolete and the computer forgotten.
Always entertaining. Had it for a few weeks and I still can't help playing with it when I pass by it on the desk. Guests absolutely love it and it's common to have a different picture on it every time they leave. A great buy!
What else can i say? The prefect gift, especially for those who love art. It can be used in times of dire boredom, if you wanted to know what your face looks like in pin form, and can then be used as a picture to be put on a shelf, so that everybody can see your face. Contemporary, cool and constantly entertaining, dont forget to add it to your basket! (I think i've said enough)
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This product was enthusiastically received by a ten-year-old and played with by the whole family, including a 6-year-old. It makes fascinating shapes and helps to understand depth.
i bought this for my boyfriend's sister, and had a go before giving it away, it's great, i had fun, and it looks good as a decoration everywhere in the house. good purchase!
This product was purchased for my grandson for his birthday he absolutely loves it he puts his face into it with his tongue out and other expressions and has us in hysterics with the results best purchase I've made lately
It's a nice feature, and everybody loves to make their own designs. Just pay attention when one of your friends takes it to the bathroom and comes back with you know what shaped pin art....!
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I bought this product for the children in my Nursery. Turns out the staff love it too! Will have to buy more so the children can get a go!


text: Share Your Story: Kaelyn Mulcahy by Anne S. on Monday, September 1, 2014 Kaelyn Mulcahy Apple Valley, MN Last year, when I was 21, I had three strokes. I was at work when the first one happened. I was dizzy and a little disoriented with a bad headache on the left side of my head and sharp pain at the back of my neck. After an hour and still not feeling well I went home. I took a nap, which is when I believe I had the next two strokes since when I woke up I was so much worse. My head hurt even more and I couldn't walk straight. I was so dizzy that it caused me to throw up four times. My roommate drove me to the ER. The doctor took a CT scan and when that was clear he ruled my symptoms as a really bad migraine. He gave me a pill for the nausea and the vertigo and told me to take Excedrin for my headache. My nausea and vertigo went away but no matter how often I took Excedrin Migraine for my headaches they never fully went away. Four days later, April 4th, I passed out at work. I called my mom and she wanted me to see my primary doctor. I had a hard time getting in to see him. It wasn't until my mom asked to speak with him personally that I got in. Bless him; he skipped his lunch on April 6th to see me. He didn't like the sound of my symptoms and was angry that the ER doctors in didn't do further testing. My doctor had me do an MRI and it showed three strokes in my cerebellum. I was immediately admitted into the ER and transferred to another hospital where I stayed for 4 days getting all kinds of tests done. Turns out I have a PFO (hole between my right and left atrial), a clotting disorder, hereditary high cholesterol, and a fainting disorder. The whole situation didn't hit me until 2 ½ weeks after I was released. I didn't know myself that summer. I was sad at first then became angry. Finally I became scared. I was scared that I would have another stroke, one that would have lasting damage, and scared for my life. Mostly I was scared that since I will be considered a high risk pregnancy, I wouldn't be able to have children, and if I could that something would happen to the baby. I was so depressed and stressed and I would snap at my roommates over everything. That's not like me at all, I always felt so bad afterwards. I had to distract my mind every second of the day or else I would break down crying. Every night I cried myself to sleep. I cried so hard I got a bunch of little blood vessels under my eyes. I didn't laugh for real until the beginning of July. I threw myself into my work; I would pick up shifts helping in lumber. I had to ask a day off every week to go to a doctor appointment, otherwise I worked every day. I didn't have a day off for myself until mid- July. Once school started again I was better. I still had to distract myself during the day but I was mostly myself again. I am a lot better now, still struggle every now and then but I am doing good. I don't want someone else my age, or anyone, to have to go through what I went through. « Now share your story Share This

subset: commoncrawl


text:
Study Break Offers a Respite From Books and Papers
By Holly Foster
Posted December 19, 2012
Tags Student Activities
Hamilton students took a break from preparing for final exams as they enjoyed an all-campus study break on Dec. 18 at the Sadove Student Center. Student Activities sponsored the event that included snowflake making, free hot cocoa, coloring, chair massages and movies. Attendees also stopped to make cards and write messages for the families affected by the tragedy in Sandy Hook, Conn.


text:
Top Definition
passing gas; a fart, toot, fluff, etc.
Hannah's boyfriend smeeched on her sweater, and now it smells like butt.
بواسطة kschooooooo أغسطس/آب 28, 2010
Trending Now
Can you define these popular missing words?
This is a west country/rural word of old. It means a burning smell or a smell so bad you think you can see it.
My mother, having been born on the Mendips in 1932 uses it alot.
My mother, having been born on the Mendips in 1932 uses it alot.
The grilled kippers left a terrible smeech in the kitchen.
The coal fire created a foggy smeech in the lounge.
The coal fire created a foggy smeech in the lounge.
بواسطة Keyte يناير/كانون الثّاني 1, 2005
"sandwich at dennys commonly used:"
Hey big kyle lets go to dennys to get that SMEECH
بواسطة smeech إبريل/نَيْسان 1, 2007
burny smell
the kitchen smells smeechy is it on fire
بواسطة susan jamieson نوفمبر/تشرين الثّاني 23, 2003
My late mother who came from Cheltenham used 'smeech' to mean 'over-heating fat', i.e. a combination of 'smoke' and 'steam' so my brother and I still thought it was only used in our family as we'd never come across anyone who knew it. but now we know better.
When I arrived at a pancake party I exclaimed 'What a smeech and everyone said 'What?''
بواسطة Cheltenham6 سبتمبر/أيلول 23, 2009
A cigarette
"dude lets go have a smeech"
بواسطة chalupaa فبراير/شباط 22, 2012


text:
Serves 6 |
Prep Time 1 hour 10 minutes |
Cook Time 0 minutes
30 ounces Eden Kidney Beans, 2 cans, rinsed and drained
1/4 cup red onion, minced
1/2 cup Eden Diced Tomatoes, drained
1 medium cucumber, peeled if waxed, chopped
1/3 cup pitted black olives, rinsed and sliced
1/4 cup Eden Extra Virgin Olive Oil
1/4 cup lemon juice, freshly squeezed
2 cloves garlic, minced
1/4 tsp freshly ground black pepper
1 Tbsp fresh oreganoor 1 tsp. dried oregano
2 Tbsp green onion, finely choppedor fresh parsley
In a large mixing bowl combine the beans, onion, tomato, cucumber and olives. In a small bowl whisk together the olive oil, lemon juice, garlic, pepper, oregano and green onions. Pour over the bean mixture and toss to thoroughly mix. Refrigerate for 1 hour before serving.
Beans, Gluten-Free, Good/High Fiber, Good/High Protein, Italian, Low Sodium, Macrobiotic, Mediterranean, No Sweetener Added, Oils, Salad, Tomatoes, Vegan, Wheat-Free


text:
Stetson University Sand Volleyball head coach Tim Loesch announced Thursday that Rachael Farrell (Niceville, Fla.), Kristin Lind (Tierp, Sweden), and Kaylee Anderson (Loxahatchee, Fla.) have joined the squad for the 2013-14 season.
Farrell comes to Stetson as a graduate student after completing her Bachelor's Degree in Health, Exercise, and Sports Science at The Citadel in Charleston, S.C. She competed for four seasons on the Bulldogs indoor volleyball team, and ranked among the top 15 career leaders in kills, digs, and total attacks. She led the team with 267 kills her senior year.
Farrell will have one season of eligibility for the Hatters as she pursues her MBA degree.
"Rachael brings maturity, leadership and huge potential with her from The Citadel," Loesch said. "Having played against her indoors, we know that she is a strong attacker, a tough competitor and a great teammate. Once she learns our system of play in the sand she will be a tremendous asset to our team."
Lind, meanwhile, will journey to DeLand from Sweden, where she was a gold medalist at the U19 Swedish Beach Volleyball Championships in 2011, and a bronze medalist at the U21 Swedish Championships. She also placed fifth on the Swedish Beach Tour in 2012, and 13th at the U20 European Championships.
"Kristin adds some more international experience to our team," Loesch said. "She has been well coached with solid fundamentals and she brings a slightly different style of play to our team. Her competitiveness and dedication to the game should make her a strong contributor to our program."
Anderson competed in indoor volleyball for four years at Summit Christian High School in West Palm Beach, Fla. She was a two-time all-area selection and helped lead her team to two district championships. In recent sand competitions, Anderson placed first at the Florida Beach Volleyball Tour event in Fort Myers and at the Florida HP Queen of the Beach tournament in Deerfield Beach.
"Kaylee is not satisfied with being one of the top youth beach volleyball players in Florida," Loesch said. "After committing to Stetson, the first question she had was, 'What can I do to get ready to play in college?' Over the past year she has played against tougher competition and worked hard to improve her skills and athleticism. She is going to be fun to coach, and a great partner for someone on our team."
The Hatters advanced to the Atlantic Sun Conference championship match in 2013.


text:
These high schools are tops when it comes to quality public education, according to U.S. News & World Report.
15 best U.S. high schoolsUPDATED 11:16 AM MDT Apr 24, 2013
Slideshow Central
CommentsThe views expressed are not those of this site, this station or its affiliated companies. By posting your comments you agree to accept our terms of use.blog comments powered by Disqus


text:
on September 15, 2012 - 6:44 PM
, updated September 16, 2012 at 7:50 AM
Brace yourselves, Niagara Falls and Salamanca.
If you thought it was hard trying to survive without $81 million in revenue from the Seneca Indian casinos in your cities, think again.
It could soon get a whole lot worse: You might never see the money at all.
The Senecas are warning that, if the nation comes out the victor in its battle against New York State, the tribe doesn't ever have to make the payments that help the cities that are host to the casinos - Niagara Falls, Salamanca and Buffalo.
"The Nation fully anticipates that it will successfully show in the ongoing arbitration that the state violated the Nation's exclusivity rights under the compact and, therefore, the Nation has no obligation to make exclusivity payments to the state," Seneca President Robert Odawi Porter wrote in a letter to Niagara Falls Mayor Paul A. Dyster.
In its compact agreement with New York State that allowed the casinos, the Senecas agreed to pay a portion of slot machine profits to the host communities, but the state also agreed not to allow other casino gambling near the Indian sites. The Senecas stopped making the payments, arguing that the exclusivity had been violated with slot machines at local racing tracks.
Now the tensions have escalated, and Porter's letter last week is a marked change from earlier Seneca positions, Dyster said, one that has Niagara Falls and Salamanca worrying if they will ever receive the money.
In fact, if the Senecas win their arbitration with the state, the decision of whether to pay anything to the host communities would then be up to the Seneca Tribal Council, Porter said. So if Niagara Falls wants to see its money, it better tone down its language, he warned.
"The financial difficulty the city is experiencing could become more problematic for the city when taking into account the overtly hostile approach your recent comments reflect," Porter wrote.
The letter marked Porter's second retort in two days to Dyster's threat to pull fire service from the Seneca Niagara Casino, a move that escalated the conflict to a new level and shed light on just how much the city is suffering without the casino cash.
The threat came, after all, from Dyster, a former arms control negotiator for the U.S. State Department who has a reputation for a cool head and not a fiery tongue.
Even Porter, the Seneca president, told Dyster he had "never struck me as one to make brash decisions."
The Niagara Falls is owed $58 million, Salamanca is owed $23 million and Buffalo $9 million, but Buffalo has not budgeted for the casino money and thus is not as adversely affected. Salamanca and Niagara Falls count on the money for everything from roads to tourism projects to debt payments.
In fact, Dyster's threat was brought on, many say, by the city's looming financial crisis, which has become more evident in recent days as the mayor prepares his budget for the 2013 fiscal year.
Niagara Falls City Hall sources are pointing to Oct. 1 as the date when they will find out the mayor will propose layoffs.
If the money from the Senecas never came, "that would put us in a huge hole," Dyster said.
"We wouldn't just have bleak prospects looking forward, but now we're looking backward. That sort of situation is grossly unfair," he said.
Welcome to our world, Salamanca Mayor Jeffrey L. Pond said.
The Southern Tier city, home to the Seneca Allegany Casino, has been on life support since 2010, when the Senecas stopped making the payments. The city fired more than 60 percent if its work force and is asking for its second no-interest loan from the state to get through next year.
"We think we're going to get the $2.5 million, but we're out of money in January," Pond said of the loan.
If the state denies the loan, he said, "the city would probably cease to operate."
Pond hasn't made any threats to stop providing service to the Seneca Allegany Casino. After all, he said, city firefighters couldn't handle a fire there by themselves, anyway.
"We could not handle it with the staff we have," he said.
Porter, the Seneca president, said the cities should take up their problems with the state, which he believes is legally obligated to pay the host communities regardless of whether the Senecas pay New York.
The Senecas have said they have no obligation to make the payments because they believe the state violated the exclusivity contained in the New York-Seneca compact by allowing casino gambling on non-Indian lands near the Indian casinos.
A spokesman for Gov. Andrew M. Cuomo did not return messages left for comment about whether the state is willing to offer the Falls a loan similar to the one it gave to Salamanca. Dyster said there are "all kinds of discussions under way" between the city and the state but declined to comment further.
Arbitration between the Senecas and state is reportedly under way, but the two cities can't receive their money fast enough.
"Both the Seneca Nation of Indians and the state have a lot more ability to wait out the results of this than we do," Dyster said. "We've been a good citizen in this. Our backs our against the wall."
email: firstname.lastname@example.com


text:
Top Definition
The most beautiful girl ever. She is untouchable, and any guy she gets with better know how lucky they are. This girl has guys waitin in line one by one, and bitches keep hatin! This girl wont take your shit! She is one of a kind aint no one else like her!
"I wanna be like Angelica!"
av ANGGGGGEL 16. desember 2008
Trending Now
Can you define these popular missing words?
one of the beautiful girls who isint a slut. They stand up for what they believe in and DO NOT take shit from anybody. Mess with an Angelica, and you will be miserable, as she is smart and knows her ways. Usually brunette with brown eyes. They play hard to get and are VERY outgoing. They dream big and are ambitious. She dominates everyone and everything. She is the leader of the group. Everyone wants to be her friend and look up to her. They are VERY confident and never ever let anyone intimidate them. They have hot tempers but are very sweet and love to help people. Girls hate on Angelica, but its all out of jealousy. They love fashion and always look good. They can get what they want, but dont act like brats. They are sensitive when friends hurt them in anyway. They dont kiss and tell, but are shy sometimes. They are very funny and know how to make you laugh. Be friends with an Angelica. They are awesome and an amazing friend. Losing them would the most horrible mistake, keeping them would be the best decision.
Boy: So how far have you gone with a guy?
Angelica: Oh wouldn't you love to know.;)
Boy: I know you play hard to get.(;
Angelica: you know me well, but i don't kiss and tell;)
Angelica: Oh wouldn't you love to know.;)
Boy: I know you play hard to get.(;
Angelica: you know me well, but i don't kiss and tell;)
av mommmma* 24. juli 2010
A girl who has the looks, the smarts, & is really into Paramore & Starbucks. Hanging out with her is the best. Plus, you'll be laughing all the way to Imagination Lane until you get crocodile tears or until water comes out of your nose.
Angelica is so fun to be with that water came out of my nose!
av adamsapol 22. juli 2008
A girl who is kind of lowkey the shit. Super gorgeous and has really good taste in music and style and who is super outgoing and lovable on nearly all levels. Characterized by brown hair and eyes.
Wow that girl is an Angelica.
av CleeakaGeorgeLopez 1. desember 2010
A sweet smelling, caring, and loving latina with a big booty! She doesn't take crap from anybody and will destroy you mentally and physically if you do so. She is so nice and sweet, you'll want to hug her every moment of your lifetime!!!!! :D Smart, but also a great kisser ;)
Angelica, with her big booty, walked up to me with the scent of starburst and gave me the greatest kiss of all time!
av AngieLover2.5 6. desember 2010
An amazing girl who digs all kinds of music. A pushover at times and kills with kindness. Loves to play sports but may be shy at times.
Wow, that girl is a real Angelica!
av Lollicopter 23. februar 2011
An outstanding, beautiful girl. She has many crushes, and a lot of guys want her. Except she is afraid of saying 'I Love You' because she doesn't want to get hurt. She is not a brat, but has many haters, but they only hate out of jealousy. She is smart with many friends, and one of the most amazing friends I have ever had. She is strong, and has good will. She is all for peace. <3 Which is one of the reasons she is known as the "Hippie" at our school.
I love you Angelica. You are my best friend!
I love you Angelica. You are my best friend!
Me- Why in this world, are so many people for the love of power.
Angelica- Because our generation has not acted up yet. But once we do, it is not the love of power we will make stronger, but only a new saying, a new feeling, and a new life style: The Power of Love
Angelica- Because our generation has not acted up yet. But once we do, it is not the love of power we will make stronger, but only a new saying, a new feeling, and a new life style: The Power of Love
av BetterIfKeptUnknown 2. desember 2010


text:
Wall Street Decline Takes Its Toll...
As Immunotherapy Revolutionizes the Cancer Treatment...
LC-MS Gains Favor Due To the...
NSCLC is "Major Battlefield" as Merck,...
More than half (52%) of the companies comprising the tissue engineering (TE) and stem cell industries are revenue-generating, compared to about 21% four years ago, according to an analysis published in Tissue Engineering Part B. Of those companies, 31% having commercial products and 21% are service-based; another 30% have products in clinical trials.
"Today, the industry has begun to understand how to manufacture and market TE and stem cell products, sustaining itself and still growing," concludes a team of authors led by Robert Langer, Sc.D., David H. Koch Institute Professor at the Massachusetts Institute of Technology.
The data collected by Dr. Langer and colleagues between 2007 and mid-2011 "suggest the TE and stem cell industry has stabilized and is on a path pointing toward continued success," state the authors in the article entitled Progress in the Tissue Engineering and Stem Cell Industry: Are We There Yet?
They report that the industry is just attaining profitability, with sales revenues reaching $3.5 billion and industry spending approaching $3.6 billion, and "appears to be on a positive trajectory," although they anticipate "that there may be growth pains as the industry matures."
Up until his passing in 2009, Michael Lysaght, Ph.D., professor at the Center for Biomedical Engineering at Brown University, had periodically tracked the growth of the tissue engineering and stem cell industry, publishing his findings in Tissue Engineering.
More than a decade ago he wrote, "tissue engineering research and development was being pursued by 3,300 scientists and support staff in more than 70 startup companies or business units with a combined annual expenditure of over $600 million."
A follow-up accounting in 2008 concluded the following: "As of mid-2007 approximately 50 firms or business units with over 3,000 employees offered commercial tissue-regenerative products or services with generally profitable annual sales in excess of $1.3 billion…In addition, 100 development-stage companies with over 55 products in FDA-level clinical trials and other preclinical stages employed 2,500 scientists or support personnel and spent 850 million development dollars in 2007.
"These totals represent a remarkable recovery from the downturn of 2000–2002, at which time tissue engineering was in shambles because of disappointing product launches, failed regulatory trials, and the general investment pullback following the dot-com crash."
The 2012 analysis by Dr. Langer's group reported a nearly threefold increase in commercial sales for TE and stem cell products and services compared to the previous four-year period. Furthermore, the number of companies selling products or offering services increased by more than twofold to 106.
Although the industry remains a long way off from achieving its potential, the fact that it has matured sufficiently to reach the break-even point shows that "clearly it is making an impact on patients' lives and on worldwide industry," says Dr. Langer.
"The growth over recent years has certainly been encouraging and is evidence that businesses can be made of tissue-engineered/regenerative medicine products," says Chris Gemmiti, Ph.D., chairperson of the Tissue Engineering Industry Council and product director, oral regeneration, Organogenesis. "I expect the field to continue along the path of productivity, but as an industry, we still have plenty of room for improvement and have not yet reached our fullest potential."
Tissue Engineering journal formed the Industry Council for the purpose of helping to guide the evolution of the industry and to create strategic initiatives aimed at overcoming some of the R&D, manufacturing, and regulatory challenges facing the industry.
"The hype in the 1990s got ahead of the reality," says Laura Nikalson, M.D., Ph.D., a member of the Industry Council, founder of Humacyte, and professor in the department of anesthesiology and biomedical engineering, Yale School of Engineering and Applied Sciences. Throughout the 1990s, TE companies were so overhyped and overvalued that by 2002 many had folded or were near folding and in trouble, she notes. By 2007, there was a resurgence and TE companies were starting to sell products.
"Some had become profitable and interesting enough so that in the last couple of years we have seen some major acquisitions of cell therapy companies, which I didn't think would happen this soon." Examples include the acquisition by Shire Pharmaceuticals of Advanced BioHealing in 2011 and of Pervasis Therapeutics in 2012.
As the current report notes, "The line between TE technology and other types of medical technology is often not clear and highly dependent upon the definitions imposed at the time." In the analysis by Dr. Langer and co-authors, "TE and regenerative medicine are used interchangeably. Further, stem cell therapeutics are included, consisting of both cell-based therapies and stem cell banking."
Defining the scope of the TE, regenerative medicine, and stem cell industries can be challenging. The definition has been somewhat of a moving target, and understanding what products and services do and do not fall within the scope of the definition is critical to interpreting and understanding an economic analysis such as this one.
For example, the authors of the 2007–2011 analysis in Tissue Engineering opted to exclude Dendreon's cell-based immunotherapeutic Provenge® from their data. Although "often touted as a breakthrough TE technology," stated the authors, "it does not provide any regenerative or reconstructive function to a damaged organ or tissue. Dendreon is at the commercial stage and generates about $72 million in sales. Had they been included, the industry market cap would have been drastically increased by $1.86 billion."
The 2012 analysis excludes research focused on cancer stem cell therapy and "all medical technology in the cancer space." The authors chose to include stem cell banking companies as commercial entities in the stem cell industry. They also included contract research organizations (CROs) that provide services for other TE firms in their analysis.
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Novum Pharma recently raised the price of an acne cream by over 3,900% in less than a year-and-a-half and Mylan increased price of EpiPen from $100 to $608 . Do you think pharmaceutical companies need to be subjected to price controls?
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I live in Columbus and have family in Toledo so I have a chance to go to many CBJ games and a few DRW games a year. I don't know about you guys, but when I end up going to games its because I wanted to go and made a decision to go. I love hockey so I always enjoy myself and don't really care if the guy next to me is doing a crossword puzzle or some vapid businessman not there for hockey, I am going to have a good time because there is hockey being played. Hockey games aren't the only place I have ever been where people lack self-awarness, I don't know about you guys.
Shame on people for being so bitter about little things, and if I had good seats and an empty seat and someone wanted my extra I would most certainly give it up and not worry if my coat has a good seat. I can see getting upset if you have children and people around you are being belligerent but even than, you know you're going to a place where they serve alcohol. ENJOY THE GAME PEOPLE!!


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on November 15, 2012 - 11:16 PM
, updated November 16, 2012 at 7:58 AM
After being turned down by County Executive Mark C. Poloncarz, leaders of the Buffalo & Erie County Public Library took their plea for an additional $3.3 million to county legislators during a budget hearing Thursday.
There already is a $300,000 increase in library funding in the proposed county budget for 2013, and Library Director Mary Jean Jakubowski said $3.3 million more is needed to restore hours and programs that were trimmed during the last two years.
"While we sincerely appreciate the proposed $300,000 increase in funding, it does not come anywhere near to what the system has requested, nor does it allow us to fully restore open hours, services, materials or staffing levels to support such operations," Jakubowski told lawmakers.
Poloncarz has proposed a budget that would give the system's 37 libraries $22.2 million next year, an increase of $300,000. But that fell well short of a public campaign the library conducted to press for $3.6 million more from the county next year to restore library hours and other programs that were cut under then-County Executive Chris Collins.
The library had encouraged patrons to send thousands of postcards to the county executive as he prepared his budget proposal.
"I must stress very clearly that our staff is doing a tremendous job stretching and eking and pulling out every last dime that they can and utilizing any types of economies of scale," Jakubowski said. "That's what puts us at this critical juncture. We are walking a very thin line toward having to reduce services and hours further."
Library officials had hoped to use the funds to keep branches open more hours and to revive library programs that had been reduced when the library's budget was cut in 2011.
"I don't think you're going to find this administration has the same mentality toward the library system as the former administration did," Deputy Budget Director Timothy C. Callan said. "Given the fiscal realities and problems facing the county for next year, we could not give the library $3.6 million in additional support."
Poloncarz has proposed a $1.38 billion budget that would increase property taxes by 3.4 percent to fill a budget hole that remained after his staff used surplus funds to balance the budget. The county, he said, is faced with several factors, including declining revenue, increasing costs for health care and other benefits, and dwindling grant money.
It was not clear Thursday how legislators will react to the request from the library as they finalize the budget during the next few weeks. Several legislators have said they hope to eliminate the proposed property tax hike and are looking for areas of the budget to cut.
Jakubowski said after the meeting that she owed it to patrons to make the funding request to restore library services. "Very clearly, we appreciate the situation and the circumstances," Jakubowski said. "But we are here for the public, and the public is asking us for more services, so we must ask for this additional funding."
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Systemwide Events Calendar
Some linguistic consequences of slavery in the United States by Dr. John BaughJanuary 22, 12:00pm - 1:30pm
Manoa Campus, Center for Korean Studies Auditorium
This presentation is devoted to sociolinguistic analyses of African American vernacular English (AAVE), including studies of morphophonemic variation and analyses of copula variability among black speakers across the United States.
Tense and Aspect in AAVE will also be discussed, especially regarding the usage of "steady" as in "They be steady runnin'." A combination of synchronic and diachronic evidence confirms that the history of AAVE differs greatly from that of United States citizens and residents whose ancestors immigrated to that country of their own volition, especially if they spoke languages other than English. John Ogbu's studies of caste-like minorities have been integrated into quantitative analyses of AAVE.
Some misconceptions about AAVE will be introduced, along with a review of the Oakland Ebonics controversy and its relevance to the linguistic behavior of black youth in South Africa, Brazil, and France; that is, along with the global influence of Hip Hop culture. The discussion concludes with relevance to educational and legal policies that are derived from sociolinguistic findings.
Event Sponsor
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|Tuesday, January 22
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Maui Campus, Pilina Bldg., Wellness Center
|Boot Up The Computer
Maui Campus, The Learning Center
|Student Involvement Fair
Manoa Campus, Campus Center
|Evcyclopedias Ancient and Modern
Manoa Campus, History Dept. Library Sakamaki Hall A201
|Some linguistic consequences of slavery in the United States by Dr. John Baugh
Manoa Campus, Center for Korean Studies Auditorium
|Study Keys
Maui Campus, The Learning Center
|Japanese Flower Arranging - Ikebana Sogetsu
Windward Campus, Hale Kuhina 115
|Hawaii Space Lecture Series
Manoa Campus, POST 544
- Highlighted dates have scheduled events.
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- Lineage : A Family Tree of Printmakers
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- Biggest Loser Challenge Sign-Up
- Arts Exhibition: Ainu Treasures: A Living Tradition in Northern Japan


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We welcome applications for the ninth Spring Academy, which will take place at Heidelberg University from March 26 to March 30, 2012. The annual Spring Academy is an interdisciplinary conference hosted by the Heidelberg Center for American Studies (HCA). A group of twenty Ph.D. students will be given the opportunity to present and discuss their Ph.D. projects. Experts in different fields of American Studies will comment on the papers and will offer workshops on various topics. Further conference details are available at www.hca-springacademy.de.
We encourage applications that range broadly across the arts, humanities, and social sciences and pursue an interdisciplinary approach. Papers can be presented on any subject relating to the study of the United States. Previous Spring Academies included panels on:
• Political Activism and Protest Coalitions,
• (De)Constructing Race,
• African American Visual Culture and Literature,
• Ethnic Identities,
• American Society and Public Opinion,
• U.S. Legal Regulations
• Trade and Politics,
• U.S. and the Far East,
• Intellectual Designs
as well as several panels on gender, religion, popular culture and sports, and various aspects of American history in general.
For the 2012 Spring Academy, panels are still being put together to cover all the conference's various research areas.
We are especially interested in papers completing the panels on:
- Religion and Identity
- Film & Cinema
- Native American Studies
- History of Sexuality
- Environmental History; Historical disaster/climate impact research
- Urban Studies and Metropolitan History
- Public Intellectuals
- Education/Social Justice
Topics not mentioned here are also welcomed for consideration.
Participants will prepare a 20-minute presentation of their research project, which will be followed by a 40-minute discussion. Presentations will be arranged thematically in ten panel groups.
Accommodation will be covered by the Heidelberg Center for American Studies.
Thanks to the generous support of HCA benefactor Herbert A. Jung, we have a small Travel Fund available to cover travel expenses for participants registered and residing in developing and soft-currency countries. Scholarship applicants will need to document the necessity for financial aid and explain how they plan to cover any potentially remaining expenses. In addition, a letter of recommendation from their doctoral advisor is required.
APPLICATIONS WILL BE ACCEPTED UNTIL: December 15, 2011
SELECTIONS WILL BE MADE BY: January 15, 2012
PLEASE USE OUR ONLINE APPLICATION SYSTEM: www.hca-springacademy.de
MORE INFORMATION: www.hca.uni-heidelberg.de
FOR FURTHER QUESTIONS: firstname.lastname@example.com


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Thunderstorm Warnings issued until 11:15 a.m.
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UN Security Meeting Debates Deadly Syrian Crisis
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UN Security Council members are calling for further cessation of hostilities in Syria as well as greater humanitarian assistance as the crisis is ongoing. (Sept. 25)
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Marlins Ace Jose Fernandez Dies in Boat Accident
Jose Fernandez, the ace right-hander for the Miami Marlins who escaped Cuba to become one of baseball's brightest stars, was killed in a boating accident early Sunday morning. Fernandez was 24. (Sept. 25)
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Speed through the highlights from the latest "This Week."
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George Stephanopoulos goes one-on-one with British Foreign Secretary Boris Johnson.
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The Powerhouse Roundtable preview the upcoming presidential debate.
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Clinton, Trump Prepare to Battle in Pivotal First Debate
George Stephanopoulos previews the first debate showdown on "This Week."
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Raw: Charlotte Protests After Video Release
A fifth day of protests in Charlotte against the fatal shooting of Keith Lamont Scott by police remained largely peaceful after the release of the partial police vehicle dashcam and police body cam footage. (Sept. 25)
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Gary Johnson Takes 'Great Pride' in Offering Alternative on Presidential Ballot
Gov. Gary Johnson makes his case for the White House on "This Week."
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A woman who was inside a Washington state mall when a gunman opened fire - fatally shooting five - says she's "thankful for my life this morning." (Sept. 25)


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Thanks to Denise Davis for her interest in our young people, as expressed in her letter (Herald, Nov. 9), �Family, societal influences hamper students.� She mentions declining test scores may be linked to the escalation of drug and alcohol addiction. From reading the headlines, one might think that substance use among the young simply increases every year. Fortunately, our perceptions do not always match reality.
Case in point is that in La Plata County, youngsters� (grades six through 12) substance use has decreased during the last two years. The three school districts participate in the biennial Healthy Kids Colorado Survey, and results from the 2011-12 La Plata County survey showed 30-day cigarette use decreased 33 percent, alcohol use decreased 16 percent and marijuana use decreased 6.6 percent. While there may be many reasons this is happening, one is surely the increased awareness that adults have a role in building developmental assets for our young people that in turn reduces risk-taking behavior such as substance abuse.
Some examples of how local adults are doing this include being positive role models, being that one caring adult for a child who is not his or her own and by fostering positive family communication and setting clear rules. Hats off to the �Lasso Tobacco � Celebrating Community Norms Coalition and the Children, Youth and Family Master Plan� for spreading the assets message in our community.
Lauren Patterson


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Expanding Use of NGS Has Largely...
Wall Street Decline Takes Its Toll...
LC-MS Gains Favor Due To the...
Developers of DTC Genetic Testing Are...
Cell-based assays are powerful tools for monitoring response to external activation signals in living cells. Recognition of this fact has been responsible for roughly 40% growth in the industry in 2008, according to SMI Conferences, which recently sponsored a symposium on the topic. The meeting showcased new developments, including many different automated platforms, new assays for hepatotoxicity, and assays based on the application of transient gene expression, transmembrane receptors, and pluripotent stem cells.
"Of the many reasons for escalating clinical costs, failure due to toxicity holds the promise of being successfully addressed with new, discovery-stage tools," said Katya Tsaioun, Ph.D., president of Apredica. Dr. Tsaioun argued that while technologies such as toxicogenomics and high-content imaging have the potential to hold down costs in the long run, predictive assays could speed clinical trials and lower their costs in a much shorter time frame.
According to Dr. Tsaioun, toxicity is a chronic and growing problem in drug development. She cited 12 drug withdrawals from the market between 1999 and 2001, three of which were due to toxicity that was missed during the development stage. A particularly egregious example was the antibiotic Trovafloxacin, which was withdrawn from the market due to its association with hepatotoxicity.
Studies have found animal testing to be only 50% accurate in predicting hepatotoxicity, with a large number of false positives and false negatives. "Improving hepatotoxic predictivity with an assay of 60% sensitivity and 90% specificity would save at least $150 million per year," Dr. Tsaioun stated.
Hepatoxicity is a poorly understood phenomenon; in some cases, patients may worsen even after treatment with a suspected agent is terminated. Tests that look for reactive intermediates generated by drug metabolism have proven inadequate for the task since they look at only a single mechanism. Dr. Tsaioun has developed a multiparameter assay that evaluates a number of markers and is predictive of hepatoxicity even in the absence of cellular death. This approach encompasses a number of features, including cell loss, nuclear morphology, DNA content, cell membrane permeability, mitochondrial membrane potential changes, and cytochrome C release from the mitochondria.
Dr. Tsaioun and her colleagues use quantitative algorithms that score responses from 0 to 100%. The methodology was validated using several agents known to be or not to be hepatoxic, which provided a well-founded set of values on the basis of which each agent can be ranked.
"We believe that in vitro approaches with human cells are powerful tools for evaluation of the hepatotoxicity risk of early leads," Dr. Tsaioun stated. "No one readout or assay is sufficient to definitively predict hepatotoxicity, but a multiparameter cell-based approach can yield insights when single mechanism readouts fail. Certainly, they are more cost-effective at this stage of development than animal studies and potentially more accurate."
James Brady, Ph.D., director of technical applications at MaxCyte, believes that transient transfection systems offer a host of advantages that have largely been ignored. The company's MaxCyte STX® system is used for developing cell-based assays. "We prefer transient transfection over stable transfection for a variety of reasons," he said. "These include decreased time and cost of production, better control of the expression process, and the ability of the system to handle expression of toxic gene products."
The MaxCyte system uses an electroporation technology designed to move small molecules, antigens, and nucleic acids into all varieties of cells. Using the green fluorescent protein gene as a convenient marker, Dr. Brady demonstrated that a number of well-known cell lines such as VERO, NIH 3T3, and CHO could be transfected with greater than 90% efficiency.
Following transfection, cells can be stored and recovered through cryopreservation with minimal loss of activity. Dr. Brady described a number of case studies in which different targets were successfully transfected such as the β2 adrenergic receptor into CHO cells and the M1 muscarinic receptor into HEK 293 cells. Transient and stably transfected cell lines show comparable levels of performance, he added.
Ion-channel expressing stable cell lines are especially problematic, thus representing an apt target for the MaxCyte technology. Their construction and validation is time consuming and expensive, and because expression of multiple subunits may involve a number of different genes (up to four in some cases), multiple selection with a number of antibiotics could be required. The presence of several antibiotics can lower cell viability and performance.
Using data shared by MaxCyte STX customers, Dr. Brady illustrated how multisubunit calcium channels can be expressed efficiently in transiently transfected HEK 293 cells. He also showed how the transfected cells can be used to screen ion-channel inhibitors using an automated calcium flux assay that is widely used for high-throughput screening.
K. John Morrow Jr., Ph.D. ([email protected]), is president of Newport Biotech and a contributing editor for GEN. Web: www.newportbiotech.com.
K. John Morrow Jr., Ph.D. ([email protected]), is president of Newport Biotech and a contributing editor for GEN. Web: www.newportbiotech.com.
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Ranked among the nation's most integrated healthcare systems, Community Health Network is Central Indiana's leader in providing convenient access to exceptional healthcare services, where and when patients need them—in hospitals, health pavilions, workplaces, schools and homes.
(HealthDay News) -- If your favorite TV shows are pulling you away from your workout, why not combine the two?
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Harold and McA, you took the words out of my mouth so I won't repeat a point already made.
My father is one of these guys who thinks there's some league wide conspiracy against the Wings, from Gary Bettman, to the referees, to the commentators. At least a couple times a season I have to remind him that we're the winningest team in the last 2 decades. If there is indeed a giant conspiracy against the Wings, it's the least successful conspiracy of all time.
That's pretty damn funny.


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The Stetson women's basketball team learned Thursday that the Mercer Bears will be its opponent in the seminals of the 2013 General Shale Atlantic Sun Conference Championship at 2:30 p.m. Friday afternoon.
The Bears defeated Jacksonville 63-53 in Thursday's quarterfinal action.
Stetson (22-8) swept the season series from Mercer (20-10), defeating the Bears 74-41 in Macon and 74-60 in DeLand.
The game will be broadcast live on CSS-TV with Paul Crane and Dee Romine calling the action. For those outside the CSS coverage area, the game can be seen on ESPN3, the WatchESPN App on mobile devices, and ASun.TV.
Bill Topping will call the action on WSBB, 1230 AM New Smyrna Beach, 1490 AM DeLand, and on myam1230.com.


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Top Definition
emmett is a word meaning Pimp. If your an emmett ur a pimp. another meaning is a cool guy.
what an emmett with all thoes chicks. i wish i was an emmett!
作者 emmetts the man 2006年6月21日
Trending Now
Can you define these popular missing words?
An attractive man with a huge penis, he is also a good in bed and great at kissing!
I went home with an emmett last night.
作者 bballer88 2010年7月21日
Emmett is an amazing guy. He's the type to keep a smile on your face even when he's not around. He's the best thing that could happen to you.
He's the best thing that happened to me. I love Emmett
He's the best thing that happened to me. I love Emmett
作者 omunique 2014年1月07日
The type of guy who falls asleep whilst on the toilet and goes home covered in Jam.
Hey, did you see emmett last night?" "Yeah, I had to take a leak in the sink, so i covered him in Jam
作者 Wrestletastic 2011年4月13日
An Emmett is a really funny guy who will do almost anything to make other people happy. He chooses others over himself and is also very generous. He knows how to make the mood great and makes everyone around him happy. He's also very talented. An Emmett is usually a great match with a Jasmine.
Girl 1: I wish I had a great guy...
Girl 2: You mean like an Emmett?
Girl 1: Exactly!
Girl 2: You mean like an Emmett?
Girl 1: Exactly!
作者 OmgTomato 2015年10月16日
1. A wannabe gangster/emo felon who is a very naughty boy and is attracted to whores. nasty whores
2. Penis
2. Penis
hey did u see emmett last night?" "no all i saw was a tall guy cutting himself with his grills while a no-boobed whore was sucking his vagina
作者 merrrrrrrrrrrrrrr 2010年9月02日
An Emmett would be commonly used to describe a guy with a penis the size of someones thigh. A heartbreaker. Cheater. Liar. Someone rough in bed. Lover. Someone fun to be with when you around them. Funny. Confused. Stupid. A drop out. Someone who dates multiple girls, but is truly only attracted to one. A pothead. Someone who looks truly happy with a woman named Katrina. Someone who loves giraffes.
holy shit nigga. did u know Greg dates dat gurl Selena?" "hellll ya brah, i heard he screwed dat gurrrl Marissa too at Carly's house" "that's such an Emmett move.
作者 Len & Carry 2011年6月29日


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Governor Walker proclaims October "Co-op Month"
Governor Walker proclaims October "Co-op Month"
Governor Scott Walker's recent signing of an official proclamation declaring October "Co-op Month" in Wisconsin is a highlight in a year-long celebration recognizing 2012 as the International Year of Cooperatives.
October is traditionally recognized as "Cooperative Month" throughout the nation, a time when cooperatives and their members make a special effort to educate the public about their member-owned and member-controlled business form. Throughout 2012, cooperatives have been celebrating the International Year of Cooperatives, which was proclaimed by the United Nations General Assembly to recognize the diversity of the cooperative movement around the world and the role of the cooperative business model in achieving economical viability, while also contributing social and community benefits. "Cooperatives Build a Better World" is the theme for this year's October Month celebrations.
"This year October Co-op Month is particularly special, as it is the pinnacle of our 2012 International Year of Cooperatives celebration," said Bill Oemichen, president and CEO of Cooperative Network, the organization that requested the Co-op Month proclamation. Cooperative Network is a trade association that serves more than 600 member-cooperative businesses in Wisconsin and Minnesota.
"Wisconsin has a proud cooperative heritage, and we appreciate Governor Walker's proclamation which recognizes the significant contributions cooperative businesses make in the Badger state. Today, some 2.7 million Wisconsin citizens depend on approximately 650 co-ops to market and supply agricultural products as well as to provide credit, electricity, telephone service, health care, housing, insurance, and many other products and services," Oemichen said.
The proclamation signed by Governor Walker recognizes that "cooperatives play a major role in Wisconsin's economy, annually recording about $8.6 billion in revenue, employing approximately 19,000 Wisconsin residents and paying nearly $780 million in wages and benefits each year."
The first official October Co-op Month proclamation was signed in Minnesota in 1948. The October Co-op Month celebration soon spread to other states, and in 1964, then U.S. Secretary of Agriculture Orville Freeman proclaimed the first national Co-op Month.
This year's theme, "Cooperatives Build a Better World," highlights some of the values that set cooperatives apart from for-profit businesses: cooperative buying power and economic advantage; community commitment and interaction; democratic principles; and people helping people.


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Rogue pharmacies are one the most commonly occurring pharmacies online that offer nearly all types of medicines and supplements without any need to have a prescription with you. This is an illegal way to sell medicine and provides great threat to everyone's health. They offer nearly all kinds of accessories like baby feeding items, baby food, baby formula food items, first aid kit, make up items, vitamins and dummies.
All of these items are most commonly used by most of the people and people love to have them easily where possible. The basic reason why people tend to buy from such pharmacies is that they provide an easy access to all of the commonly used medications and items without any hindrances os documents required. That's why people lose their focus on the quality of the products and just enjoy their easy access and low rates despite the fact they are also getting low quality products.
Now the question comes how these pharmacies sell their products easily and have no shame in doing so
All these tactics are used to attract people to buy low quality drugs and medicines and such pharmacies should be avoided and only the traditional online pharmacies or pharmacies with remote consultation should be considered in order to buy medicines online.
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Enroll Now!
Create and post your very own Web site on the Internet using HTML in this extensive, hands-on, six week workshop. First, you'll learn about the capabilities of the World Wide Web and the fundamentals of web design. Then, with your instructor's patient guidance, you'll plan the content, structure and layout of your Web site, create pages full of neatly formatted text, build links between the pages and to the outside world, and add color, backgrounds, graphics, and tables. You'll also learn critical and timely information on securing the best possible location in search engine listings, and powerful no-cost or low-cost web marketing strategies.
With over 100 published books to his name, award-winning author Alan Simpson is widely regarded as a computer and Internet guru. His books have been published throughout the world in over a dozen languages. Alan is a seasoned veteran of the computer industry, and his books and online courses cover virtually all aspects of the computer industry, including Web development, operating systems, word processing, spreadsheets, databases, programming, networking, and security.


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An NHL player says the NHL made a new offer to the NHLPA on Thursday, one which moved on contract term limits, buyouts and variance...
NHL Deputy Commissioner Bill Daly would not confirm it when reached
NHL offer calls for term limit on player contracts to be six years (7 if you're re-signing your own guys).
New offer sees each team afforded one compliance buyout prior to 2013-14 season. Doesn't count vs. cap but it does vs. players' share
Also the Make Whole $$$$ stays at $300 million
At this point there is no scheduled meeting between both sides set for today. NHLPA needs time to review lengthy and detailed offer from NHL
Among the changes in the new proposal, the NHL adjusted its max contract length from 5 to 6 yrs. Boosted the variance from 5% to 10%
Hard to imagine the NHL's latest proposal doesn't result in potentially season-saving meetings. Players wanted flexibility and they got it.
Sounds like the league has made some interesting concessions, moving towards the players on the contracting issues. Also interesting to see that the league is offering each team one compliance buyout to get back under the cap.


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6 People Who Mixed Bad Luck with Stupidity
The world is literally up to its nuts in dummies. We'll say up to the left nut. The right nut is bobbing on the surface of the unlucky peoples who populate the Earth. And somewhere just below the taint are the people who are both unlucky and stupid and who mix those two qualities together in a Molotov cocktail of derptarded chicanery that makes you feel bad for them for only as long as it takes you to point and laugh, because sympathy has boundaries. These are their stories (insert Law & Order *Doink-Doink* here).
#6. The Rasta Banana Man
Name something more fun than carnival games. Did you say sex? A good meal? Friendship? Well-fitting shorts? Pie? Stop, this is getting stupid. Aside from most things, there's nothing more fun than a carnival game. So it's no surprise that a man whose name is Henry Gribbohm (and not the sound he makes when he gets his own fist jammed in his esophagus while trying to eat Goldfish crackers) was so smitten with the games when the carnies rolled their gypsy fun-wagons into his town.
The game was called Tubs of Fun, and the play involved finding fun in some kind of tub. Henry, seeing that one of the prizes was an Xbox Kinect, knew he was about to play the carnies like a cat plays a fiddle, which is to say all fucky and wrong. He spent $2,600 trying to win that Xbox and came away with nothing but a 3-foot-long Rastafarian banana. Dumbasses the world over heaved a sigh of relief and knew if ever a day came when someone placed a call for King of the Idiots, they were not at the top of the list. And then, as one, they put on their helmets and ran headfirst into a bull's hindquarters.
Gribbohm was pretty confident that he had the game down before he started playing. Unfortunately, $300 into the game he hadn't won, and he suspected something must have been up. So he went home and retrieved his life savings, another $2,300, which he probably kept in a cigar box in the cat box. After losing that sum, he called the police to inform them the game was rigged. Police then had to confirm whether or not Gribbohm feels Tetris is rigged when he loses or if the toilet is rigged when he has diarrhea.
#5. Carjacking Pants Dropper
Brand X Pictures/Brand X Pictures/Getty Images
I don't know about you, but every time I steal a car, I make sure I'm in jeggings and I've been drinking a lot of Mountain Dew to keep me spry and limber. That's because I have a passion for my craft. Elijah Freeman, however, got caught up in the glitz and glamour of auto theft and forgot the basic lessons of how to pull off a reasonable crime plus police chase.
After stealing a car at gunpoint, Freeman chose to race right onto someone's lawn, where he got out and made off like a bandit in the night, except this bandit was hobbled by stupidity. And pants.
Freeman's pants had started the evening somewhere below his waistline, as is the fashion among people who don't get why we wear pants. Running from the cops caused them to literally fall to his ankles. When he was arrested (within a few seconds, because catching a dude who's running with pants around his ankles is not hard), his pants had literally fallen completely off. It's entirely possible the proper use of a $5 belt could have seen this man riding off into the sunset to start a beautiful criminal legacy. Ahh, what might have been.
#4. Nigerian Love
Creatas/Creatas/Getty Image
Ever gotten one of those Nigerian scam emails? I remember being so stoked the first time I got one. I had read, only weeks earlier, Dean Cameron's Nigerian Spam Scam Scam and suddenly my inbox was presenting me with my very own opportunity to become a legend of Internet comedy. This was, of course, many years ago, before I became the legend of Internet comedy I am today and the one I briefly was in 2009 when I tried to restart WebVan.com as a home bourbon and Russian bride delivery service. Long story short, my efforts to scam the scammer with a hilariously crafted email response to their grab for money netted me a response that simply said "fuck you."
Unlike me, Marvin Ray Thomas was all over the Nigerian scam when his Nubian princess Jenni came a-calling and asking if he wouldn't mind setting up a simple yet effective money order scheme to defraud strangers and send the proceeds to her so that she could save up enough to come to America and marry him, her being what was likely an overweight African man named Nigel wearing khakis and a 1999 Atlanta Braves World Series Champs T-shirt. Thomas proceeded to mail fake money orders to people around the U.S. asking them to cash them on behalf of his totally legit business, send the bulk of the money back to him, and keep a little for their trouble. It was the kind of offer no one could resist, unless they had a measureable IQ. Sadly, lots of people fell for it to the tune of more than $20,000, which is a pretty impressive tune. It's not like Neil Sedaka, but easily Jon Secada. Google them, this article's not going anywhere.
The thing about asking people to cash fake money orders is that it's illegal. If there's no money behind that money order, then you're stealing. So police caught on to Thomas' scam and went to his house not once but twice to let him know that this manner of behavior was frowned upon and that Jenni probably had a penis that had no interest in putting a ring on. Despite this, Thomas couldn't see how a total stranger from Africa who was having him commit massive mail fraud could be deceiving him, so he kept doing it until police could facepalm no longer and had to indict him.


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Amount Per Serving %Daily Value
New Zealand Red Deer Antler Velvet Powder (Cervus elaphus) 500mg*
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SXSW will screen the world premieres of two films about Billie Joe Armstrong and Green Day as well as films about the racial mix in the 1960s Chicago blues world, Burning Man and the travels of Arhoolie Records founder Chris Strachwitz.
In addition, the festival will screen two films that were well-received at the recently completed Sundance Film Festival, Dave Grohl's "Sound City" and Morgan Neville's "Twenty Feet From Stardom."
SXSW announced 109 of the feature films that will screen between March 8 and 16 in Austin as part of the 20th anniversary festival. The lineup features 68 films from first-time filmmakers, 69 world premieres, 14 North American premieres and five U.S. Premieres.
"Broadway Idiot" (Director: Doug Hamilton; world premiere). Behind the curtain with Green Day lead singer, Billie Joe Armstrong, as he ventures onto Broadway with "American Idiot."
"¡Cuatro!" (Director: Tim Wheeler). A peek inside the world of Green Day as they conceptualize and record the trilogy of "¡Uno!," "¡Dos!" and "¡Tré!"
Full article at Billboard: HERE


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to bugger someone until you have no energy, it doesn't matter when you spunk, you battle on until your nackered
Up for a bugger lug
door scotty_genius 24 september 2008
Trending Now
Can you define these popular missing words?
Top Definition
Grumpy person - usually older, can be attributed to any person who is being a grumpy pain in the bum.
Ask buggerlugs over there, he'll proabably know the answer.
Come on buggerlugs, lagging behind again...
Come on buggerlugs, lagging behind again...
door easyman 30 augustus 2006
Affectionate term for a child
You're a Buggerlugs.
Hiya Buggerlugs
Hiya Buggerlugs
door Kaede351 3 november 2008
An affectionate term for a female friend, if you're from up north!
Hey buggerlugs
door Julie Steel 23 januari 2004
An affectionate term for a child, particularly when it isn't listening to the adult, the implication being that the child's ears (lugs) have been fucked (or buggered) and can no longer hear as a result.
"Oy, buggerlugs, are you listening?"
door Minjeeta 28 juli 2009
1.Someone with very large ears.
2.Ears ideal for use as handles which afford a sodomiser extra purchase and thus enable the delivery of a more thorough, forcefull bumming.
2.Ears ideal for use as handles which afford a sodomiser extra purchase and thus enable the delivery of a more thorough, forcefull bumming.
"Dude that supple boy has bugger-lugs!"
door TheGayMaker 13 december 2007
extremely ugly!
Urghh!! Your face offends my mirror bugger-lugs!
door Natalie 10 september 2003


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Average Ratings
4 out of 5 people recommended this car.
Consumer Reviews
Trusty Stratus
by Gear Head from Salt Lake City, UT | September 10, 2013
My dad has had the manual 2.0L 4 cylinder version of this for 14 years. It has never our family much trouble other than basic maintenance. Pros: Decently styled exterior, above average stock stereo, mythical gas mileage (we still see 35mpg at 100k miles on it) Cons: 4 cylinder model is a gutless wonder. You don't buy this car for thrills. Boring interior styling Overall, as long as you realize this is a basic sedan you will be pleased with this choice. It's been cheap to run and for a car this size has incredible gas mileage.
Purchased a new car
Uses car for Commuting
Does recommend this car
lemon all the way
by ed from austin tx | May 12, 2008
My father was a dodge man and we had lot of them growing up. I thought it was a good idea to get a dodge. I purchased a 4 cylinder 99 Stratus. One thing after another. It ran like a lawn mower. Hills made the car scream. It would squeal from the wheels. Took it to dealer and the couldnt figure it out. Cruise control made transmission go nuts and shift like it was going to die. Thank god they made the stereo good and loud. Thats the only thing that kept the other noises from the car out. Everyone else outside would just look and laugh. I maintained the car well but could not get the noises to stop. The dealer couldnt figure out how to fix there own car. The car lasted 2 years and caught fire in park, in front of my daughters school on her first day. It was a powerstearing leak recall. I walk out with a smile and thought thank god for full coverage. I will never buy a dodge again.
Purchased a new car
Uses car for N/A
Does not recommend this car
First Car
by LN2007 from Chicago | July 4, 2007
This is the first car I owned. I still currently own it because it is still running smoothly. The only problem i had with it was to change the pistons. The car also has good handling, a lot of leg room for the back seat, and has decent acceleration. The only thing i dont like about the car is that its pretty thirsty for gas for a 4 cylinder engine. This is a great car for unexperienced teen drivers short on cash.
Purchased a new car
Uses car for N/A
Does recommend this car
Great value. Cheap to own/operate.
by Cheapdude from Central PA. | October 3, 2006
This car has proven to be above average in terms of reliability and durability. I should know, I'm hard on vehicles. Parts and accessories are cheap, compared to other vehicles. It lacks performance but hey, it's only a little four cylinder. Good solid car. Highly recommended.
Purchased a new car
Uses car for N/A
Does recommend this car
Older Dodge Stratus V6, Still Chuggin
by Still Chuggin from Aurora, IL | May 22, 2006
My 1999 Stratus has 170,000 miles on it and has never had any major problems, but I think they may be coming soon. I can feel the transmission starting to go, and the suspension is just about shot. I've heard the 4-cylinder versions of these cars had problems and the V6s did not, and that's been the case in my experience. My cousin bought a 4-cyliner around the time I bought my V6. That car is long gone (it had a leaky head gasket I think) and mine's still going. My wife and I drove this car hard on the expressway for 5 years before retiring it to in-town duty when we bought our newer car. If you're looking at an older used Stratus, I'd just make sure it's the V6 version and the transmission still feels solid.
Purchased a new car
Uses car for N/A
Does recommend this car
Featured Services for this Dodge Stratus
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Remington UMC LeadLess Ammunition
Key Features
Virtually eliminates lead exposure
Flat nose enclosed base design
Industry-leading heavy-metal-free primer
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Oedipus Rex
Directed by LINDA BROWN
All Greek drama, including Oedipus the King, was performed in masks. Made of linen, cork, or wood, no ancient Greek mask has survived the ravages of time, but we do have several representations of Greek masks painted on Athenian vases. Though the origins of masks in the Greek theatre are shrouded in mystery, the fact remains that the mask was an accepted theatrical convention and used throughout both tragedy and comedy.
Described by Aristotle as the "perfect tragedy," Oedipus the King has held our attention for over 2000 years. What is it about this tragic hero, Oedipus, that captures our imagination? We know the story: Oedipus as the agent of the action fulfills the curse that proclaims he will kill his father and marry his mother. It is through Sophocles' brilliance as a playwright that we examine this ancient myth and watch Oedipus' journey to understand the roles of the gods, his identity, and his fate. Through his journey we too discover the "man within the myth."


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Authorities will make their case next month for trying a suburban Kansas City band teacher on charges of having sexual contact with a 14-year-old student, sometimes at school.
During a court appearance Tuesday, a judge set a Jan. 30 preliminary hearing date for 27-year-old James N. Owens. He is free on bond after being charged last month with one count each of child enticement and child molestation.
His attorney, Eric Vernon, didn't immediately return a phone call seeking comment.
Court documents allege that Owens exchanged more than 100 phone calls and more than 1,500 text messages with the girl.


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- Color
- #1 - Fair
1- Fair
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Reviewed by 2 customers
(1 of 1 customers found this review helpful)
By Dreamgirlla
from San Antonio
describe yourself Brand Buyer
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Perfect color for my fair skin! Lovely consistency and application, I find it superior to Touche eclat.
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(1 of 1 customers found this review helpful)
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Perfect for dark circles!!!
By amesoso
from CA
describe yourself Budget Buyer
- Blends Well
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The 2011 Stimulus Check: 2% Payroll Tax Holiday
|Email Print
When Congress passed an extension on the Bush tax cuts, it also passed a new one year tax "holiday" on your payroll taxes. I'm calling it the 2011 version of an old friend to many Americans, the stimulus check. Back in 2008, after the passage of the 2008 stimulus package, many Americans received $300 in the form of a stimulus check. In years since, that stimulus check has been morphed into the Making Work Pay credit (resulting in $400 per person).
For 2011, the stimulus check has returned and this time it'll be called a payroll tax holiday with a benefit of up to $2,136 per person.
Payroll Tax Holiday
Right now, employees pay a payroll tax, also called FICA tax, of 7.65% on their first $106,800 of income. 6.2% goes towards Social Security (OASDI) and 1.45% goes towards Medicare. After their first $106,800, you only pay the 1.45% of Medicare (there is no limit) and not the 6.2% towards Social Security. For 2011, the percentage you need to pay towards Social Security, as an employee, will be reduced by 2%. For someone earning the maximum $106,800, it's a reduction of $2,136. After you take out taxes, based on your tax bracket, the rest goes into your pocket.
The first stimulus check gave you $300, the next one gave you up to $400, and this one has the potential of putting over two thousand dollars into your pocket over the course of the year (minus taxes).
(Photo: Tracy O){ 90 comments, please add your thoughts now! }


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the allmighty origional champions
"yes, yes they are"
"yes, yes they are"
almay tarafından 2 Mayıs 2005, Pazartesi
Trending Now
Can you define these popular missing words?
Photos & Videos
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A shit football team who last won the league almost 50 years ago but whose fans still think they are better than The Arsenal, even though it takes roughly 9 years to beat them.
"Spurs really are a rubbish club"
Gary Lineker on Match Of The Day
Gary Lineker on Match Of The Day
sooner_gooner tarafından 17 Ağustos 2009, Pazartesi
The San Antonio Spurs are the winners of the 2005, 2003 and 1999 NBA championships.
On June 23, 05 they kicked the Detroit Pistons ass in game 7.
On June 23, 05 they kicked the Detroit Pistons ass in game 7.
"How about those Spurs?" "GO SPURS GO"
Sergio Schaar tarafından 24 Haziran 2005, Cuma
Abbreviation of the car, Bentley Continental Flying Spur. Commonly used in rap songs.
"Know it's me when you see the Spur in ya area"
"They love the Bentley and the seats in the Spur"
"They love the Bentley and the seats in the Spur"
Matt845 tarafından 5 Şubat 2009, Perşembe
To hit some in the face
Oh i spured that nigga max for talking to much shit
gotti tarafından 19 Mart 2005, Cumartesi
A spurs was an old English word to describe a Jew, who were situated in North London
Bill is a jew!!!
I hate Spurs!!!!
I hate Spurs!!!!
Mr xxxxxxxxxxxxxxxxxxx tarafından 31 Ocak 2012, Salı
justifying the moment of your idiotic thinking. You basically ask yourself : 'Why the f*** did i just say/ask that?'
"i really don't know why i just said that. It was just spur"
'spur of the moment'
'spur of the moment'
merrrrrc tarafından 26 Nisan 2013, Cuma


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Green Day attended the final sound check for the new Broadway musical inspired by their album, "American Idiot" Tuesday. The highly-anticipated show opens in April.
Billie Joe Armstrong, Tre Cool and Mike Dirnt addressed an audience of 500 fans who got a sneak preview of the show's title number. There is already buzz about the show winning a Tony for best musical.
[Full article at Huffington Post]


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You can own a piece of President-turned-painter George W. Bush's artwork in your own home.
A Christmas ornament featuring Bush's painting of a cardinal is a must-buy this holiday season at the Bush Center's Museum Store, a shop assistant tells ABC News.
"We ordered about 10,000 in total; 5,000 in red boxes and in 5,000 in green boxes," adds the assistant. "They're all just about gone."
The budding artist, whose specialties include depictions of pets and Texas landscapes, originally painted the cardinal for his friend, former ambassador Warren Tichenor. Based on its holiday-worthy aesthetic, his wife, Laura Bush, selected the painting to be featured on the ornament as well as the center's Christmas card.
"Laura liked the bright red on the cardinal and the greens of the foliage," the proud grandfather, who recently revealed a portrait of Jay Leno on a November trip to the Tonight Show, says in a video promoting the ornament (watch above). "I'm flattered and I hope my painting meets expectations."
The ornament retails for $29.98.


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on November 15, 2012 - 11:18 PM
May 1, 1928 – Nov. 8, 2012
Edgar D. Jaworski of Derby, former art director at the Courier-Express and advertising artist for S.M. Flickinger Food Co., died Nov. 8 in Absolut Care of Orchard Park. He was 84.
Mr. Jaworski was born in Buffalo and was a longtime resident of West Seneca and Derby.
He graduated from Pine Hill High School in Cheektowaga and served on an aircraft carrier during World War II.
He was selected as a young man by iconic local artist Charles Burchfield to study with him.
Mr. Jaworski worked as art director for the Courier-Express from 1954 to 1961, then from 1962 to 1969 worked as advertising artist at the West Seneca Observer and Lackawanna Leader.
Starting in 1967, he also started working at Flickinger's, printing up sales signs for the company's grocery stores by hand.
Among the signs he painted were those that appeared on Super Duper commercials in the late '60s and early '70s in which a pitchwoman named Joey circled the lowest price of the week on a selected item. He appeared in many of those commercials as the artist at the drawing board.
During the 1970s, he also launched a freelance art career from which he retired in the mid-1980s.
He showed and sold some of his works at the Allentown Art Festival.
During the 1970s, Mr. Jaworski also was an instructor of concept therapy – a way of looking at the philosophy of life.
He enjoyed playing ukulele and piano and writing his own songs. His wife, Veronica, died in 2009.
Survivors include three daughters, Joyce Zarbo, Christine Tarquin and Holly Holl; a son, Robert; and his former wife, Marie Rynski.
A service was held Monday in Buszka Funeral Home.
Mr. Jaworski donated his body to University at Buffalo Medical School.


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What has happened to "Support local business — shop local?" The transportation committee would rather pass our tax dollars to a firm in Washington state?
One that wants to help our elderly or disabled residents, but does not have a bus, let alone a fleet of them?
The county will have to purchase these vehicles, at an estimated cost of $200,000.
Also, in Nevada County double talk, "This is a long-term plan. We can't go out and buy buses tomorrow" and yet "the transit team has begun to develop a plan to procure four vehicles."
What should we believe?
Just to be clear — I would much rather see a Gold Country Telecare bus. A good, local firm, with ties to the community. A business that supports Nevada County and employs local residents. Let's keep it local.
Betty Johnson
Nevada City


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Carhartt Sweatshirts
Carhartt offers a complete selection of premium sweatshirts in midweight, heavyweight and thermal-lined fabrics. Carhartt sweatshirts are double-needle stitched for durability, and some styles include attached three-piece hoods that fit comfortably under hard hats.
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Technical information
Access starting point: Untersee
Access point of arrival: Langwies. Arrive by train from Chur to Arosa and then take the free bus (Arosa Card) to the Untersee. Return by train from Langwies to Chur.
From Zweisimmen to Lenk
Hiking time: 5 hrs
Season: Mid-June to October
Starting point: 1691 metres above sea level
Difficulty: average
Difference in elevation: Approx. 400 metres uphill and approx. 700 metres downhill
Gastronomy: Untersee lido, Alpenrose (Medergen), Heimeli (Sapün)
This little settlement with its traditional wooden cabins does not have running water or electricity. The track continues to Seejiboden, which offers a spectacular view over the Sapünertal valley and the rugged Chüpfenflue mountain. At the next path junction, turn left towards Heimeli – Sapün and head for the next hamlet. From there, take the forest track or the attractive summer path to Langwies.
Tour Overview
3D hiking map Download GPX coordinates Download KMZ (GoogleEarth)
The careful planning of a tour will ensure that you also derive the maximum pleasure and enjoyment from it. Please take the time to contact the local information centre and enquire about route and weather conditions before setting off. Your intended trail may be fully or partially closed, depending on the time of year and weather conditions.


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Eye Candy: Don't Click This Link
Dear Ann, A quick note to share a wonderful Tumblr with you and our readers. Warning: if you go to this Tumblr, you may be a while. It's addictive. It's wonderful. I want to get on a plane and fly to Santiago, Chile, to meet its proprietress, Mercedes Galarce aka Meme Galarce. I follow her on Twitter. I follow her on Instagram. I haunt her Etsy shop. The reason: I love her eye. She loves what I love. And if I didn't know...Read More