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Expanding Use of NGS Has Largely...
LC-MS Gains Favor Due To the...
As Immunotherapy Revolutionizes the Cancer Treatment...
Developers of DTC Genetic Testing Are...
The search for cancer biomarkers has proven to be a long, frustrating, and mainly fruitless exercise. Despite the substantial investment, no new markers suitable for large-scale screening protocols have achieved FDA approval. Yet, improvements in investigative tools, as well as innovative computer analysis, offer hope that the situation may be changing, and newly characterized candidates may prove to be clinically useful. At Visiongain's recent "Biomarker Conference", a number of presenters reported on putative biomarkers.
Diane Longo, Ph.D., a research scientist at Nodality, discussed the use of single-cell network profiling in the pathway analysis of cancer as a means to generate actionable clinical information. "This approach measures alterations in signaling pathways that drive disease processes and the response mechanisms of the host," she explained.
The general protocol followed by Dr. Longo and her colleagues is to obtain blood or bone marrow samples from patients, expose the cells to stimulating or inhibitory factors, fix, permeabilize, and then stain the cells with flurophore-conjugated antibodies that recognize either extracellular surface markers or intracellular signaling molecules. The cells are then subjected to multiparameter flow cytometric analysis. This approach allows for the measurement of evoked signaling at the single-cell level, capturing the response of rare cell populations and revealing signaling heterogeneity.
Translating the biological characterization of patient samples into information that can be used to guide clinical decision making required an "industrialization" of the assay that could be run in a standardized high-throughput format to ensure that the results were highly reproducible.
The single-cell, network-profiling approach of mapping signaling networks has applications in disease characterization, clinical medicine, and drug development. As an example, Dr. Longo talked about her team's work with acute myeloid leukemia (AML) in which they performed a functional characterization of intracellular signaling pathways in myeloblasts from patient samples. These studies revealed significant signaling heterogeneity among acute myeloid leukemia samples from genetically defined subgroups. Specifically, signaling heterogeneity was observed within subclasses defined by the presence or absence of a mutation in the FLT3 receptor kinase.
FLT3 internal tandem duplication mutations are among the most frequent mutations in AML and have been shown to negatively affect outcome in this disease. A functional characterization of intracellular signaling networks within individual cells from AML samples allowed for a subclassification of patients beyond their molecularly determined FLT3 mutation status and may have value in predicting clinical response.
"These studies allow us to conclude that we can identify and monitor rare cell populations," Dr. Longo explained. "Moreover, the combination of different pathway information could provide assays to inform clinical decision making. Ongoing training and validation studies will critically test the clinical validity of single-cell network profiling for disease characterization and management in acute myeloid leukemia."
Daniel Chelsky, Ph.D., CSO at Caprion Proteomics, presented his company's proteomics methodology to biomarker discovery and validation. "We combine a search for biomarkers in biological fluids with discovery in tissues, driven by highly multiplexed assays."
Dr. Chelsky's overall developmental strategy is based on MRM, a mass spectrometry assay that can specifically target large numbers of proteins. Promising biomarkers can be assembled by trolling the literature, proteomics assays, and transcript profiling. Through a validation funnel, the candidates are screened and winnowed down to the most promising possibilities.
"From this data, expression in the source tissue predicts expression in blood," Dr. Chelsky said. "We can also determine the specificity of these proteins by building a 'Body Atlas' catalog of shared vs. specific secreted proteins from a wide range of tissues. We believe that this approach, combined with highly multiplexed multiple reaction monitoring, provides a powerful tool for biomarker verification."
The company is focused on biomarker discovery using label-free, gel-free, quantitative mass spectrometry—a nonhypothesis-driven strategy, or "fishing expedition" in which thousands of proteins are profiled, narrowing down to dozens or hundreds of differentially expressed proteins. Subsequently, these are verified through a targeted approach involving multiplexed, quantitative multiple-reaction monitoring by mass spectrometry. This strategy allows large numbers of samples to be analyzed with a final aim of validation for regulatory compliance.
Caprion has pursued a number of malignant conditions such as lymphoma within the CNS. Diagnosis of this condition is fraught with difficulty, requiring expensive imaging or invasive biopsies that are dangerous and not always possible. As an alternative, cerebrospinal fluid from patients with lymphoma and matched controls was investigated, resulting in some 76 candidate markers. Among these, antithrombin III levels were found to be an accurate predictor of disease progression, providing better sensitivity and specificity than the conventional cytology, according to the company.
Given that secreted proteins are perhaps a thousand times more concentrated in the Golgi apparatus than in the blood, targeting this subcellular organelle and the attendant secretory vesicles to reveal the secretome is another promising strategy to detect markers present in very low concentrations. Caprion staff investigated the presence of biomarker proteins in prostate tumors and their normal counterpart.
Among 60 differentially expressed proteins, they were able to identify seven that were previously identified by other investigators in plasma. Two of these, prostate specific antigen and macrophage migration inhibitory factor, were measured by ELISA in the plasma and were strongly correlated with measurements in the patients' tumors.
Another series of investigations identified secreted protein indicative of progressive type 2 diabetes. By focusing on those secreted proteins found only in the beta cells, Caprion researchers identified almost 300 proteins specific to the beta cells that are currently being evaluated as candidate biomarkers.
K. John Morrow Jr., Ph.D. ([email protected]), is president of Newport Biotech and a contributing editor for GEN.
K. John Morrow Jr., Ph.D. ([email protected]), is president of Newport Biotech and a contributing editor for GEN.
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|By Kevin Benedict
Article Rating:
|February 26, 2013 09:00 AM EST
Also read Enterprise Mobility Asia News Weekly
Also read Field Mobility News Weekly
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Curalate has released a visual analytics product that analyzes user activity for both Instagram and Pinterest. "We're helping brands see the bigger picture — to engage audiences across networks based on what's most relevant rather than what's most recent." Apu Gupta, Curalate's CEO and co-founder said in a statement. Read Original Content
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subset: commoncrawl


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You had an injury or disease in your digestive system and needed an operation called an ileostomy. The operation changes the way your body gets rid of waste (stool, feces, or poop).
Now you have an opening called a stoma in your belly. Waste will pass through the stoma into a pouch that collects it. You will need to take care of your stoma and empty the pouch many times a day.
Standard ileostomy - stoma care; Brooke ileostomy - stoma care; Continent ileostomy - stoma care; Abdominal pouch - stoma care; End ileostomy - stoma care; Ostomy - stoma care
The feces that come out of the stoma can be very irritating to the skin. So it is important to take special care of the stoma to avoid damage to the skin.
After surgery, the stoma will be swollen. It will shrink over the next several weeks.
The skin around your stoma should look like it did before surgery. The best way to protect your skin is by:
Stoma appliances are either 2-piece or 1-piece sets. A 2-piece set consists of a baseplate (or wafer) and pouch. A baseplate is the part that sticks to the skin and protects it against irritation from feces. The second piece is the pouch that feces empties into. The pouch attaches to the baseplate, similar to a Tupperware cover. In a 1-piece set, the baseplate and appliance is all one piece. The baseplate usually needs to be changed only once or twice a week.
To care for your skin:
If you have hair on the skin around your stoma, your pouch may not stick. Removing the hair may help.
Carefully look at your stoma and the skin around it every time you change your pouch or barrier. If the skin around your stoma is red or wet, your pouch may not be sealed well on your stoma.
Sometimes the adhesive, skin barrier, paste, tape, or pouch may damage the skin. This may happen when you first start using a stoma, or it may happen after you have been using it for months, or even years.
If this happens:
If your stoma is leaking, your skin will get sore.
Be sure to treat any skin redness or skin changes right away, when the problem is still small. Do not allow the sore area to become larger or more irritated before asking your doctor about it.
If your stoma becomes longer than usual (sticks out from the skin more), try a cold compress, like ice wrapped in a towel, to make it go in.
You should never stick anything into your stoma, unless your doctor tells you to.
Call your doctor or nurse if:
Call your doctor if the skin around your stoma:
Also call if you:
Burch J. Caring for peristomal skin: what every nurse should know. Br J Nurs. 2010;19(3):166, 168, 170.
Cima RR. Pemberton JH. Ileostomy, colostomy, and pouches. In: Feldman M. Friedman LS, Brandt LJ. Sleisenger & Fordtran's Gastrointestinal and Liver Disease. 9th ed. Philadelphia, PA: Saunders Elsevier; 2010:chap 113.
Fry RD, Mahmoud N, Maron DJ, Ross HM, Rombeau J. Colon and rectum. In: Townsend Jr. CM, Beauchamp RD, Evers BM, Mattox KL. Sabiston Textbook of Surgery. 19th ed. Philadelphia, PA: Saunders Elsevier; 2012:chap 52.
On a mission to heal body, mind and spirit


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Acronym for Bergen County Meet of Champions, the wildest cross country race in Bergen County, NJ. This historic race has bred runners such as Pat Rono, Nick Ward, John Prizzi, and Bobby Corcoran
Scott: "Damn did you see Nick kill it at bmoc?"
Riles: "Yeah, he really destroyed the competition."
Scot: "Too bad Bobby will break his PR next year."
Riles: "Yeah, he really destroyed the competition."
Scot: "Too bad Bobby will break his PR next year."
dari Nutmeg'sfather123 Jumat, 28 Oktober 2011
Black Man on Campus, referring to a school/area where there is a severe lacking of black people.
oh, there goes desean(dequan, lebourne, etc.), he's the BMOC.
dari leeeerrrooooooooy jenkins Rabu, 05 Januari 2011
Big Man On Campus / The most dank weed you can smoke. Bmoc will make you wig out or be the most baked you have ever been.
"Damn im trippin off this BMOC"
dari Derek Foreal 30 Jumat, 24 Juli 2009
BMOC, or "Big Man on Campus" usually refers to Nate Landry, a student at OIT who dominates at all forms of life.
Lets go roll out with BMOC so people think we are cool
dari David Vranizan Jumat, 07 Januari 2005


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Thursday, September 26, 2013
Last Thursday was no different from any other school day at the O'Bryant household. Emma was up and dressed before the sun came up. Sadie was wearing a princess dress on top of her school uniform and was lying in the floor pretending she didn't know how to put on her velcro tennis shoes. Aubrey asked for five more minutes so many times that I finally told her, "I'm leaving this house in five more minutes. With or without you."
My husband, Zeb, was working out of town for a couple of days, so I packed lunches, made breakfast and herded children to the car. I dropped the girls off at school and came back home to go for a run.
For the last few months I've been working hard to get my fitness on. So as foreign as the words may appear, I did, in fact, run and no one was chasing me with a weapon of any sort. After my run, I came home feeling like the Queen of the Universe. I'd run further and faster than I ever had before, and while I wasn't going to be going to be hoping for a gold medal in 2016 — I was proud of myself.
I was still sweating when I got a call from my literary agent telling me I'd made the New York Times' best-seller list. I shouted and danced around my house, before calling my husband and the rest of my family. I spent the rest of the day on the phone with my agent, and staring at my computer screen finishing the proposal for the next book.
I was excited to pick the girls up from school — I always am, but I wanted to tell a family member in person, see someone's face light up with excitement for me.
They piled in the minivan.
"So guess what? Mommy's book got on a really important list today, all the way up to No. 3."
Aubrey put her finger in the book she had been reading in the carpool line and looked at me with her mouth hanging open, "Momma, That is so awesome."
"Gradulations, Momma," Sadie said.
"Can we go to Sonic?" Emma asked — any excuse for a slushie.
"Sure, why not?" We ordered a round of drinks and headed to the house for homework. While everyone worked at the kitchen counter, I cooked dinner. I opened a bottle of wine a friend of mine had dropped at the house earlier in the day as a congratulations and had my first glass of wine in months.
We took showers and got in bed early — all four of us piled into my bed. I laughed as the girls told me stories about their day then scolded them when they kept touching each other after I turned out the lights. I stayed up late, watching their little button noses inhale and exhale, and smooching their cheeks when I thought I could get away with it.
When I started writing five years ago, I dreamt about one day making the New York Times' list. I never imagined it would happen this soon but I can't imagine a better way to celebrate than drifting off to sleep surrounded by my three blonde muses.
Robin O'Bryant is an author, humorist and speaker. Her latest book is "Ketchup is a Vegetable and Other Lies Moms Tell Themselves." Connect with her on Facebook and Twitter and visit her blog: www.robinschicks.com.
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Local residents are offering their opinions on the stricter gun control recommendations the White House released Wednesday.
President Obama introduced a proposal that, according to information on the White House website, includes measures such as strengthening background checks, passing a more aggressive assault weapons ban, limiting ammunition to 10 rounds per magazine, pushing for more counselors in schools and enhancing coverage of mental health services for young people.
Tom Nesbitt, of Beverly, weighed in.
Article Photos
"I truly believe in being able to defend your property and yourself. There are other ways to prevent (tragedies)."
Pam Smithson
"I should (be allowed to) have a gun to protect myself," he said.
Nesbitt was vocal about equality for all citizens. He told the Inter-Mountain that citizens outside of government should have same rights as those in government, that no person or group should have special treatment.
He also said gun control laws could quickly turn into a slippery slope, where the abolition of assault weapons could soon become an abolition of all guns.
"Once it starts," he said, "(more aggressive legislation) is coming."
David Barb, of Elkins, was straightforward in his response.
"No semi-automatics," he said. "I think that's a good idea."
Barb mentioned that the right to bear arms is important, but he said assault-style weapons aren't necessary.
Tina Shreve, also of Elkins, opined her opposition to legislation that would entirely take guns away from ordinary citizens.
"I don't like it," she said. "We should be able to have guns."
However, like Barb, Shreve said she was in favor of laws that would limit the sale of assault rifles.
Residents were largely concerned with the government intruding on their personal rights and stepping into their private lives.
In line with the other respondents, Pam Smithson said she believes it's important for people to be able to protect themselves.
"I truly believe in being able to defend your property and yourself," she said.
Smithson also spoke about laws that would help people with mental illnesses. She said having access to psychological help is important and should work in tandem with any gun legislation.
"There are other ways to prevent (tragedies)," she said, noting that laws controlling the sale of certain weapons aren't the only answer.
Contact Casey Houser by email at firstname.lastname@example.com.


text:
on May 10, 2013 - 9:10 PM
, updated May 11, 2013 at 3:16 PM
Erie County Sheriff's Deputy Timothy J. Higgins' exile from the sheriff's substation in Elma is over.
Higgins, a 27-year veteran of the Erie County Sheriff's Office, will return to the substation in Elma Town Hall for his early-morning shift today as a result of a "handshake" agreement reached Friday with Town Supervisor Dennis M. Powers.
Higgins said he and Powers worked out a nonwritten "gentlemen's agreement to let bygones be bygones, and we worked out our differences and are moving on." The two held a 20-minute meeting Friday at the Iroquois School complex on Girdle Road.
Although assigned to road patrol in the Elma area, Higgins was not allowed to use the sheriff's substation in the Elma Town Hall because town officials had complained to Sheriff Timothy B. Howard about his apparent disrespect of them.
Higgins would not discuss Friday the complaints of various Elma town officials that had prompted Howard to honor the town's request.
In late March, thanks to arbitration proceedings launched by Higgins' labor union representatives, arbitrator Michael Lewandowski found "not one scrap of evidence" to support complaints about Higgins by Elma officials. The arbitrator also ordered Howard to pay Higgins $8,300 for time he lost over the dispute. "I'm still trying to get that from the sheriff," Higgins said Friday.
Efforts to reach Powers on Friday evening were unsuccessful
Powers previously told The Buffalo News that Higgins had threatened the Town Board in connection with a town employee and a political feud in that part of the county.
Higgins recently dropped a notice of claim he had filed against the town in February 2012 concerning a part-time court officer's job he lost, which apparently contributed to the resolution of the dispute with the town.
During the 2011 town judge race, Higgins had openly favored incumbent Joseph A. Sakowski, who won re-election over a Town Board member who had sought the judicial post. That contributed to the dispute in town hall, sources close to the case said.
Higgins is the son of Thomas F. Higgins, who served as Erie County sheriff from 1986 to 1997.
The substation based in Elma Town Hall covers Elma, Marilla and Wales.
email: email@example.com


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Katniss Everdeen's (Jennifer Lawrence's) life was difficult enough before she was forced to try to kill 23 other children on national television.
Fatherless and starving in District 12, the mining center of dystopian future world Panem, she takes her little sister Prim's (Willow Shields's) place as a tribute, fighting to the death in an elaborate spectacle broadcast as a reality show.
To add poison to the sting, Katniss is expected to kill her own teammate, Peeta (The Kids Are All Right's charming Josh Hutcherson), a sweet boy who has a crush on her.
Yes, The Hunger Games is feral, but its unwillingness to coddle its young audience is what made author Suzanne Collins's trilogy such a hit. The movie sticks close to the first book, with detail-perfect renderings of the districts, the Capitol, the arena – and certainly of Katniss.
Lawrence, an Oscar nominee last year for Winter's Bone, is a fan's dream. With her soulful eyes and innate grit, she gives skilled hunter Katniss equal doses of complexity and appeal. Forget Twilight's insipid Bella Swan. This is a literary heroine girls can cherish.
Woody Harrelson, Elizabeth Banks and Lenny Kravitz have marvelous supporting roles, but the film isn't always as strong as its stars. Its subtleties may get lost on viewers new to the story. Still, it's so fiendishly engaging the even darker, scarier sequels can't come fast enough.


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on May 13, 2013 - 2:55 PM
An orphaned polar bear cub will arrive in Buffalo Wednesday from the Alaska Zoo.
The bear, named Kali, will be flying into the UPS Shipping Facility at the Buffalo Niagara International Airport in the early-morning hours.
The cub will soon have a roommate in Luna, a female polar bear cub who was born at the Buffalo Zoo in November who has been attracting large crowds during her viewing hours in recent weeks.


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5 Products That Improve the Love Lives of Creepy Sociopaths
The Internet is full of product reviews, but if you're anything like me, you've found them lacking something: rampant, selfish idiocy. I propose to fix that by telling you not only about all of these exciting new products, but also how to recklessly abuse them in order to best augment your terrible, immoral lifestyle. For example: You need love, but the outside world is where they make you wear pants, and you can't spit on the floor if people are watching. So what are you -- the agoraphobic pathologically lying asshole -- to do? Well, here are five cutting-edge new products that might help you finally seal the deal on that shady online relationship!
*This guide is structured in two parts: First, the basic product review and introduction. Then, the field test, where I use each of said products toward a clearly nefarious end and hopefully never suffer the much-deserved repercussions.
#5. Brainput Multitasking Assistant
Solovey, et al via Popular Science
It's clear to me that I can't handle the day-to-day of maintaining a relationship. My long list of ex-girlfriends with broken hearts and broken front doors can attest to that. But finally, I think I've isolated the problem: I'm just too devoted to my work. Much like how Einstein was purported to frequently leave the house with his dick hanging out of his pantaloons (his head too lost in higher mathematics to be bogged down with something as pedestrian as wang wranglin'), I, too, am simply so immersed in my chosen profession of whatever it is I'm supposed to be doing for a living that I cannot manage a normal relationship. (I think I might be some sort of snake handler. I don't know. I keep waking up full of venom and with a bunch of snake skins all around me -- snake handler is the least disturbing explanation I can come up with.)
So enters the Brainput Multitasking Assistant: It's still in prototype stages right now, but when finished, this computer program will monitor your vital signs and stress levels, then automatically take some of your more mundane tasks off of you to lighten your mental load.
Doud et al, 2011 via University of Minnesota
Ostensibly, it's meant to take over basic stuff like email replies and schedule updating, leaving you to focus on the more creative thinking. But I've found that, with some simple hacking, it can be reprioritized to pretend to listen to loved ones while you get drunk to old Knight Rider reruns. But be warned: It doesn't really factor in your personality very well. Twice now it's agreed to go on "long walks" with potential mates, no matter how emphatically I hammer-type my anti-effort manifesto into its response field.
#4. Anigao Girls
It's the single most common complaint regarding online dating from narcissistic sociopaths: Everybody's ugly except for me! It's nearly impossible to find somebody as pretty as you are on today's Internet -- much less one who's willing to put on all your clothes and hold a tape recorder playing your voice while you make love to yourself. For thousands of years, the issue of physical attraction has put the kibosh on perfectly good relationships, but finally, somebody has the answer! And that answer is as laughably simple as it is almost certainly some sort of sex crime: Just put a custom-built rubber mask over their heads!
The uh ... the country with the answer was Japan, incidentally.
They're called Anigao Girls: high-rent escorts that cater to jaded otaku who can no longer get it up for a human face, but have found dry-humping their computer monitor while anime is playing to be ultimately somewhat flat and slippery. Those dead, lifeless schoolgirl eyes are great for Japanese nerds and all, but me personally? I've never gotten over my first and only true love: Blanche from The Golden Girls.
My wilted flower! O, my leathery love! To be the rice in your pudding ...
But now, thanks to the wonders of 3-D printing and some fascinatingly shameless Japanese escorts, even my needs can finally be satisfied! My horrible, blasphemous needs.
#3. Hiro III Haptic Interface
This is the HIRO III, a haptic interface peripheral designed by a Japanese robotics firm. It boasts 15 independent motors that provide real-time force feedback to the user's hand, allowing exact simulation of the heft and shape of virtual 3-D objects.
We are clearly going to be using this stunning advance in robotics to cybernetically grope some reluctant boobies across a span of continents. Did I even have to type that? Some truths are held to be self-evident.


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This site complies with the Health on the Net Foundation Code for trustworthy health information: verify here.
Antioxidants are believed to have substantial health benefits and raspberries in particular are a good source. In fact, raspberries may have 10 times more antioxidants than tomatoes or broccoli. Further, raspberries contain some specific antioxidants that are found almost nowhere else.
In a study published in a recent issue of BioFactors, researchers from Plant Research International, Wageningen, The Netherlands, discuss specific compounds found in the berry, some appropriate methods for assaying the antioxidant concentration, and the biochemistry of antioxidant uptake in humans.
"Raspberries contain vitamin C and anthocanines," says Jules Beekwilder, "but these can also be found in other products. However, approximately 50% of the antioxidant effect of raspberries is caused by ellagitannins. These you find in small doses in strawberries and practically nowhere else." Some Chinese herbs may also be a source of these compounds.
The authors describe a special testing method for analyzing the antioxidant activity of raspberries. They point out that any beneficial effects will likely come from rapid chemical reactions between the antioxidant and the target molecule in the body. In a standard testing procedure, these rapid reactions may be missed, leading to confusing or conflicting results. By measuring these reactions in a 30-second window, a clearer picture of antioxidant capacity can be developed.
Because raspberries spoil rapidly, the study discusses the effect of storage and processing on the antioxidant content of the fruit. While flash freezing in liquid nitrogen and storage at -20°C destroys much of the vitamin C, the antioxidant capacity remains. Processing the berry into jams may alter some of the antioxidants, however most of the valuable compounds remain.
There is also some evidence that certain raspberry cultivars or varieties are higher in antioxidant capacity than others. The authors suggest that selective plant breeding could result in "extra healthy" raspberries, but that consumers tend to favor a better tasting and cheaper berry. According to Beekwilder and his colleagues, "It is clear that raspberry, like several other fruits and vegetables such as tomato, strawberry, kiwi and broccoli, represents a valuable contrasting source of potentially healthy compounds and can represent an important component of a balanced diet."
For more information view the following article:
Beekwilder, Jules. Identification and dietary relevance of antioxidants from raspberry. Robert D. Hall and C. H. Ric de Vos. BioFactors, Volume 23, Issue 4, 2005 (Special Issue EUROBERRY: Highlights on Bioactive Behavior of Berry Fruits). IOS Press.
To view related articles on the EUFIC website go to Functional Foods.


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Top Definition
An old person whos white hair appears blue. Usally it is the only thing you can see over the steering wheel of the car they are driving.
Damn blue hair, get off the road
JohnH가 작성 2005년 05월 13일 (금)
Trending Now
Can you define these popular missing words?
An old person who should have their drivers license revoked because they can't see over the goddamn steering wheel.
If this blue hair doesn't kick it up to at least 20 mph on the freeway, I'm gonna run his ass into the guard rail and wave the double duece at him....AAAAUGGGHHH !!!
Poster Nutbag가 작성 2003년 06월 03일 (화)
Noun: An eldery female, usually with curled, grey-blue hair.
The bluehair cut me off in the fast lane.
Scaryberry가 작성 2004년 01월 21일 (수)
One of the hottest hair-dye colours.
Shares the title with: red, green, pink, orange, purple, and black.
ClockworkRose가 작성 2005년 01월 08일 (토)
An old person, but especially a slick, well-dressed retiree that still thinks that they have it going on.
After the U of A game, all the Arizona blue hairs made a run for the border to score some cheap Viagra in Nogales.
J Willard가 작성 2008년 01월 12일 (토)
Blue hair is a nessesity.
I just got blue hair today and im suprisingly happy!
sophia가 작성 2003년 08월 31일 (일)
A necessity in anime. All the characters should have blue hair.
And for some reason, Id have blue hair. I mean, you gotta have blue hair. -Strong Bad
!가 작성 2003년 04월 05일 (토)


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does anybody know if is true that the leader of the akuski is naurto's brouther.
sorry i dont no. Naruto has a bro?!?
sorry T_T "everyone knows something but nobody knows everything"
no ur completely off the leader pein only has a relation past wise to khonan he has no relation to naruto once so ever
the leader of the akuski is not narutos brother but he is narutos dads brother
"In A Girls Life We Like To Shop, Well I Dont!!"
ME! (But seriously) Whom?
"In A Girls Life We Like To Shop, Well I Dont!!"


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Maholm Shoots Blanks at Friars
Paul Maholm and three relievers combined to toss a six-hit shutout, as a split squad oif Cubs blanked the San Diego Padres 2-0 this afternoon in Cactus League action at Dwight Patterson Field at HoHoKam Park in sunny Mesa, AZ
Maholm threw five innings of shutout ball (70 pitches - 40 strikes, 6/2 GO/FO), allowing no runs on four hits and two walks, with six strikeouts.
Carlos Marmol followed Maholm to the mound, and labored through his one inning of work, throwing 22 pitches while allowing a walk and a single, but no runs. Something still does not look right with Marmol.
Casey Coleman continued to pitch well in Cactus League games, tossing two shutout innings of one hit ball. It looks like Coleman could make the Cubs Opening Day MLB 25-man roster as a RH middle-reliever or as the "12th man" (long reliever/spot starter).
RHP Rafael Dolis notched the save with a scoreles 9th, although two runners did reach base with two outs, one on a strike three wild pitch, and another on a walk, before Dolis induced a game-ending 4-3 ground out. Although there has been talk about Dolis beginning the season in the big leagues as one of the Cubs set-up men, it might be best to let him close at AAA Iowa for a while and work on improving his command.
There wasn't much offense on display at HoHoKam Park today, but the Cubs did push across a run in the 1st and then another run in the 2nd against Padres starter Tim Stauffer.
Starlin Castro singled with two outs in the 1st, and after stealing 2nd, scored on a Bryan LaHair two-out RBI double off the fence in right-centerfield, and Reed Johnson knocked-in the second Cub run on a two-out RBI ground single ripped through through the box into CF, scoring Jeff Baker, who led-off the inning with a screaming double into left-center.
What really stood out today, however, was the Cub outfield defense.
Tony Campana hustled to field a bloop hit down the LF line in the top of the 5th, and after a 360-spin, uncorked a perfect throw to 2nd base to nail Will Venable trying stretch the hit into a double, Reed Johnson followed Campana's play with a fine running catch on a line drive to end the 5th, and Daytina CF Matt Szczur (up from Minor League Camp for the day) made tte defensive play of the afternoon, a diving catch of a line-drive in right-center for the first-out in the top of the 9th.
While one squad of Cubs was blanking the Padres in Mesa, the other squad traveled up to Salt River Fields at Talking Stick to play the Arizona Diamondbacks, losing 3-2.
I wasn't at that game, but D'backs starter Ian Kennedy threw seven innings of one-run ball, the only Cub run scoring on back-to-back doubles by Blake DeWitt and Ian Stewart in the top of the 7th.
Iowa Cubs RHP Jay Jackson got the start at Salt River Fields, and allowed all three of the Arizona runs on seven hits (including three doubles and a Paul Goldschmidt HR) and one walk over his four innings of work.
This was the last Cubs split squad day of the 2012 Cactus League season, so it would seem likely that the final roster cuts will be forthcoming soon.
Re: Maholm Shoots Blanks at Friars
Beautiful day at Hohokam today, Phil, although I was focused on my 1-year-old.
Thanks for the recap as always!
Re: Maholm Shoots Blanks at Friars
exploding scoreboard has nothing on this...
we all knew it was coming based on the drawings, but seeing it completed and working is just...sad/eerie/facepalm/etc.
Re: Maholm Shoots Blanks at Friars
Looks like something you'd find at one of those depressing travelling carnivals, right next to the Bearded Lady freak show and the guy who guesses your weight.
Re: Maholm Shoots Blanks at Friars
Yeah. Reminds me of shooting gallery. Possibly the tackiest thing in MLB for home runs I have ever seen
Re: Maholm Shoots Blanks at Friars
If they really wanted to make it interesting, they'd have a Sarah Palin look-a-like shooting the dolphins as they circle up.
Re: Maholm Shoots Blanks at Friars
No politics please.
Re: Maholm Shoots Blanks at Friars
1) I didn't say anything pro or con regarding Palin. Just a funny visual for me.
2) Sarah Palin is no longer part of the political world's talking points. She is nothing more than a celebrity at this point in her career. Next thing I know, you'll be trying to censor references to other marvelous celebrities, like Dennis Rodman.
Re: Maholm Shoots Blanks at Friars
saw him last week at LAX getting thrown out of a Chilis...rodman, that is.
he ordered a beer, sat down, a manager came out of the back and told him he's not allowed in the restaurant (i guess he's had run-ins before)...he picked up his beer (still in glass), said "fuck this." and walked out with glass-in-hand into the airport commons.
he was dropping off and holding a "day bag" for mellissa rivers (joan's daughter).
rodman walking out with a beer in a glass in one hand and a purse-thing overflowing with scarves out of the other.
woo LA.
Re: Maholm Shoots Blanks at Friars
Yup, I saw an article on the Trib's site today about how he is broke and sick (I guess not too sick to swill a beer, tho) and therefore, can't pay his child support, for which he owes about 800k. He's the poster child for kids who think they can do whatever they want when they find some success, especially in sports. I get the sense his fuse is just about fizzled out.
Re: Maholm Shoots Blanks at Friars
he was sober...or mostly sober...or "working alcoholic" sober at the time, but while he didn't look ravaged he was showing his age. he was working that beer hard before he left and on his way out.
Re: Maholm Shoots Blanks at Friars
The disturbing silence perfectly mirrors an actual Marlins game.
Re: Maholm Shoots Blanks at Friars
Marlin's "exploding" scoreboard -- had to be the result of the ingestion of some industrial strength hallucinogens.
Re: Maholm Shoots Blanks at Friars
Center fielder Marlon Byrd's name is making the rounds in the final-week-of-spring hot stove as the Cubs try to bolster a thin bullpen and teams such as the Washington Nationals and Atlanta Braves try to shore up outfield needs.
Re: Maholm Shoots Blanks at Friars
While I expect Byrd to be traded at some point during the season, there is no rush and I don't think they care about receiving something that fills a hole in the current roster.
Re: Maholm Shoots Blanks at Friars
With Campana and Skinny Dick in camp, why bother filling the current hole? They just need to keep the seat warm for a couple months.
Re: Maholm Shoots Blanks at Friars
I think the hole in the roster is in the bullpen.
And I'm sure the Cubs would rather receive a marginally interesting prospect than a throw away bullpen arm. If they could flip Byrd for a young reliever, that might do, though.
Re: Maholm Shoots Blanks at Friars
exploding scoreboard has nothing on this...
reminds me of this, if you substitute a marlin for the chocolate easter bunny:
Re: Maholm Shoots Blanks at Friars
Buster Olney mentioned that a number of teams, including D-Backs and Phillies, are looking for catching right now.
I wonder how strong a market for Soto would be right now.
Also, Castillo is clearly not "polished" at this point, but if thrust into action, I wonder if people think he could be "ready," by which I mean at least passable.
Re: Maholm Shoots Blanks at Friars
When Castillo is as "ready" as he is ever going to be, he isn't going to make enough contact to be a first string catcher. And the Cubs have no one who will be ready in the next two or three years.
They better not trade Soto unless they are truly "blown away", and that isn't very likely.
Re: Maholm Shoots Blanks at Friars
That's a pretty bold statement about a 24-y-o who had an 875 OPS at AAA last year and a rocket launcher of a throwing arm.
Re: Maholm Shoots Blanks at Friars
Yeah, I was pretty sure that I had read AZ Phil's take on Wellington that he really just needed work on his receiving. After that, he would be ready to be an everyday catcher, and he would hit well.
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I don't think he will ever make enough contact to be a first string catcher. When I see him, I see Henry Blanco.
Everyone has their own opinion.
Re: Maholm Shoots Blanks at Friars
I could see Blanco. He's always been compared to the Molina brothers, more Yadier due to their ages being closer. I tend to think he could be a mix between Bengie and Jose. Actually, I could see him as a Wilson Ramos type, or Rod Barajas.
I guess, I'm not really agreeing or disagreeing. He has the skillset to be a starting backstop, but if he can't hit for a positionally-passable average, yeah, that could "doom" him as a starter. I tend to think he'll float around the .230-.260 range, given a full allotment of AB's, so IF he provides solid defense and power, I think he could start, akin to how some of the above guys can start.
Re: Maholm Shoots Blanks at Friars
Castillo's got enough power to be a starting Catcher in the majors as long has he can manage a .240+ average or so, if he has his defense together.
Not a top tier catcher unless he can hit for average, though--don't see him hitting 25+ homeruns consistently.
Re: Maholm Shoots Blanks at Friars
well, to be fair, Castillo isn't likely to hit for a high average.
That said, the flip side is, if he can provide power, a passable average for the position, and be solid behind the plate, well ... there are plenty of starting catchers that don't offer that.
I'm also in the camp that believes that at some point, Soto should be moved because the chances of Geovany being a key part of our next core is ... quite minimal. I doubt we'd get a huge return right now, though, so I'm thinking that mid-season, if Soto is having a good year, might make more sense, particularly if teams have injuries (of course, this is premised on the idea that Soto stays healthy and is having a good year.
Re: Maholm Shoots Blanks at Friars
If a catcher that hits between 230 and 260 with some power and passable defense, then Soto is a much better option. At about 29 years of age, if he is too old to be a part of the next core, you have an awful pessimistic view of the new management.
If we can get a great deal for Soto, then we should trade him, just as we should trade Castro if we can get a great deal for him. We should trade ANYONE if we can get more in return than we give up.
But trading Soto now because we think he is going to decline in the next year or two doesn't seem very realistic to me.
By the way, if I were to guess, I think that Clevenger would make a better starting catcher than Castillo over the next 5 years or so. Other than his arm, which is extremely strong, Castillo isn't an exceptional defensive catcher, from what I have seen and heard of him.
Re: Maholm Shoots Blanks at Friars
I am just parroting things that i have seen AZ Phil write in the past, but he generally described Clevenger as a MLB-backup type that was probably ready for duty. Castillo was described as someone who needed more work, but who could absolutely displace Soto when ready. I don't know if his views of this have changed...
Re: Maholm Shoots Blanks at Friars
Not to fear gents - you know Koyie Hill is available now.
Re: Maholm Shoots Blanks at Friars
Thanks a lot!
I just peed a little bit...
Re: Maholm Shoots Blanks at Friars
That is pretty much what I remember ArizonaPhil as saying.
And I have great respect for Phil and his reporting is probably the best I have ever seen in providing information about unknown young Cub prospects that have not been seen or heard of in the baseball community in general and Cub fans in particular.
But there ARE other sources, as well as stats over the course of Castillo's career, and I have personally seen him play a fair amount of time. It is my opinion that Castillo will not provide enough contact at the plate to be an every day catcher, just as Blanco did not.
As far as Clevenger is concerned, that is probably a result of my own personal prejudices. I value contact and OBA more highly than many fans, and I think that Clevenger will provide more of what the new administration seems to value. He has a good eye at the plate. He takes pitchers deep into the account. He doesn't strike out a lot, and has a relatively high walk rate, resulting in a pretty good OBA that I think will translate well into the majors.
Time will tell.
Re: Maholm Shoots Blanks at Friars
That said, I think we'd all be in agreement there is a bit of flexibility in a 73-win team.
Re: Maholm Shoots Blanks at Friars
Low average ... some power ... passable defense ... sounds a lot like Soto. Who makes less? Who can be traded for another ballplayer?
Re: Maholm Shoots Blanks at Friars
Soto has two years of low average, and two years of average higher than I think Castillo will ever reach. And in spite of two pretty terrible years, Soto still has an OBA higher than most of the catchers the Cubs have had in years.
I don't think that Castillo will approach an offensive career as good as Soto has had up til now, and in my opinion, Soto is likely to do better if he learns to control his weight.
Re: Maholm Shoots Blanks at Friars
Soto is clearly the better offensive player. Batting average, yeah it's one stat ... but Castillo has an OPS of 875 as a 24-y-o in his first year at Iowa; Soto had a 723 OPS as a 23-y-o at Iowa for the first time, then broke through with a 1062 OPS as a 24-y-o. Both men tend to see their averages rise and fall with BABIP, but Soto on average will hit for a higher average than Castillo ever will.
But what I've read tends to have Castillo long-term as a better defensive catcher. His arm, from what AZ says, is for real. He has enough power potential to be a threat. He's just entering the prime of his career. And his service clock is under 0.1 right now.
So what's Soto worth? You and I don't know. But this came up because Olney wrote that there's a strong demand in the market for catchers right now. At $4M, most teams can afford Soto - and if not, then the Cubs can afford to eat a couple million. What would he bring back? Like I said, no way for you and I to know for sure. What if it's a couple of near-ready prospects? What about Tyler Skaggs? What does an extra $4M buy next offseason - a quality RP?
So yes, you'd clearly step backwards at C in the short term. But in the long term, you get a guy who many project to be a MLB starter in the position; you get more money to spend other places; and if you get another guy or two back who also project to help in 2013 and beyond, then it's probably a good deal.
Batting average be damned.
Re: Maholm Shoots Blanks at Friars
If you trade Soto because you get a great offer, that makes sense.
If you trade Soto because you think he will not be around long enough to be on a winning Cubs team, that may be a toss up.
If you trade Soto because you think Castillo will have a better career, I don't think that makes a lot of sense.
Re: Maholm Shoots Blanks at Friars
I agree with that.
I would only add that, due to aging, I suspect their values will likely be equal by 2014, maybe 2015 at the latest. Yes, the Cubs will compete by 2014. What about before? I don't know.
Re: Maholm Shoots Blanks at Friars
i honestly expect soto to be gone by july...clevenger deserves to be a backup, but that's pretty much his ceiling. at best he profiles as light hitting catcher. welly at least has starter qualities.
even if welly hits .250/.330 avg/ob% he should be able to smack a good number of doubles with 15+ homers bringing up the end of the lineup...and that's a rather average expectation out of him. with his arm and pop he should be more than passable as a starter even if it's not all-star caliber.
Re: Maholm Shoots Blanks at Friars
well, first off, for me, a leads to b. That is, I don't think he's going to be a part of the next core, and as such, i think trading him earlier (again, I haven't suggested trading him now, i said midseason in another post above), when we could get more in return, makes more sense.
So let's start with a. I've said elsewhere, but I think, realistically, 2014 is the earliest that we can hope that our next window (that is, period of years where we are competitive for playoff spots) could open. There's no harm in wishful thinking on 2013, but with a young group of guys likely to be manning key positions (hopefully), it just seems unrealistic, even if we go on a free agent splurge.
So, in 2014, Soto will be at the end of his prime years while our new window is opening up. If I'm, not mistaken, 2014 will also be at the end of his team-controlled years. so
a) It would seem debatable as to whether or not that this current regime would give him that long term deal. Varitek was kept around as much for his leadership as his ability. I'm not sure Soto is viewed in that manner.
b) The chances, and note, I did say chance, are high that Soto will likely see some decline in his 30's. So, even if he is around in his mid-30's there is a good chance that Soto will be more of a secondary asset than a part of the core.
It's possible Soto bucks the norm and is some sort of non-performance enhancing player that excels in his mid-30's. I'd bet against it. So, for me, I'm thinking like this -
a) We keep a guy who, at best, will have a year or two in our window where he is in the tail end of his prime years.
b) We trade him (not haphazardly, but only if a good trade comes along) for assets that will have a greater chance of being a key part of our next core.
And for me, I lean to the latter.
As for Clevenger, I've long noted elsewhere that I have a level of irrational interest in him. I like him quite a bit, and I've never been as high on Castillo (when Tampa came calling for a catcher, I preferred keeping Chirinos around, but he's another guy who is on the same level as these two). Having seen both play, I tend to think both (and Chirinos) are borderline starter-types if things go well, but quite possibly, stopgap starters who eventually get replaced. I'm not sold yet that Clevenger will hit for a significantly high enough average against big league pitching to compensate for his deficiencies power wise and defensively (he's a steady eddie behind the plate, but ... well ... Ryan Theriot was a steady eddie ... obviously different positions/different dynamics, but the point is, Clevenger will be steady defensively, but to expect more is probably questionable). Castillo has the arm, and he has the athletic ability to be better behind the plate (and he's improved from 2 years ago).
Re: Maholm Shoots Blanks at Friars
I'm in the same camp as you. If Theo can find a deal that benefits the Cubs beyond 2012 by trading Soto, I make the deal now, at the trade deadline, after the World Series.......whenever. Given what Soto is likely to produce in 2012 and 2013 and the cost ($4M+ per season), and a Clevenger/Castillo platoon, this move is a no-brainer to me.
Re: Maholm Shoots Blanks at Friars
Feel sorry for those who don't play up to their contracts-
Re: Maholm Shoots Blanks at Friars
This hilarious exchange between Boston dudes on Espn.com is intelligent, is very complimentary of Hoyer ... And I seriously laughed my ass off several times. Don't skim - read it, you'll thank me:
Not 3/44 on this I hope?
Re: Maholm Shoots Blanks at Friars
I would be OK with more journalism like this.
Re: Maholm Shoots Blanks at Friars
Re: Maholm Shoots Blanks at Friars
If Samardzija has a decent season, he maybe my new favorite Cub
Re: Maholm Shoots Blanks at Friars
j.mather playing 3rd again...seems they're taking b.dewitt out of the 3rd-backup situation and not considering j.baker, either.
Re: Maholm Shoots Blanks at Friars
What else does Mather have to please you, man!?!?!?!
Sell peanuts?!?!?
He's awesome, and not in the Scott McClain/Jake Fox way.
Re: Maholm Shoots Blanks at Friars
You know, I don't think Theo has to worry about payroll dollars. However, if Mather could produce essentially what DeWitt and/or Baker will playing for the minimum (or close to it), I wouldn't hesitate to make that move as well. Have over half the roster playing for auto-renewal, and spend your major money to keep key home-grown talent (Castro, etc.) and fill in FA's.
Re: Maholm Shoots Blanks at Friars
That's always been my take on it. If you can fill out half the positions on the field with pretty decent/solid players at pre-FA rates that's a huge win. Lock up Castro and other significant up and comers with Tampa Bay type deals buying out the ARB years and 2-3 FA years and then repeat. I have lots of confidence in Theo to get this to happen. That's when you can go out and spend big on a FA or two to fill in the holes.
Re: Maholm Shoots Blanks at Friars
s.camp 2ip 2h 0r 1bb 2k
Re: Maholm Shoots Blanks at Friars
And Welington Castillo hits a solo HR in the 9th to give the Cubs a 4-3 lead
Re: Maholm Shoots Blanks at Friars
And then Sappelt with a 3 run blast, LaHair doubles (3-5 day) after that...
Re: Maholm Shoots Blanks at Friars
Thanks CUBSTER!
Re: Maholm Shoots Blanks at Friars
LaHair's gotten hot during the last few days. It's the right time in spring training to get hot if you're guaranteed a roster spot.
Recent comments
j.buchanan with a nice start...5ip 2h 1bb 3k, 0r/er
zobrist with 2HR and a double through 8
heyward 0-4 :(
Mark Gonzales @MDGonzales
Soler likely to return Sunday, Maddon says
Right now, I'd like to see the Mets first, Giants 2nd.
I believe that since most of the team from last years' NLCS is on the squad this year, they will really amp their game up even more to kick their ass in payback for 2015.
The Giants just do not have the depth in years past, and I think all things equal - and at Wrigley - they could handle them.
I do not want to see the Cards, period. Or their fans, media, or Joe Buck.
I don't want to play Braves in the first round. Any friggin team in the league can win 3 of 5..I hate the first round. Furthermore, I wanted to play the Marlins in 2003 and the Mets over Dodgers last year.
With that said in reverse order:
3. Cardinals: It will be devastating to lose in the first round, but even worse to their main rival. It is increased incentive for the Cardinals, especially after last year. Cards would have nothing to lose, Cubs have everything to lose.
2. Giants: Rotation in the playoffs scare me a bit, but what a lousy team.
1. Mets--because of the losses in the rotation
2. Giants--because they're not the team they were BUT they maybe have bullshit even-year magic?
3. Cardinals--because rivalry and not making the playoffs hurts them more than losing in the NLDS plus getting eliminated by them in the playoffs would make for horrible sports commentary next throughout next season.
Who's asking?
CLE/DET rained out last night already, possible rain-outs in New York (vs. Baltimore), Boston(vs. Toronto) and Philly(vs. Mets) this weekend too.
Not only games involving playoff spots that would need to be played, but any that involve home field advantage.
I got the first one! Second one I'm not even sure what even/odd betting is.
any opponent preference for NLDS?
Mets are down to 1 great pitcher instead of 4. Syndegaard may pitch Sunday which means if Mets win the WC game, he'd be set up for Game 1. There's a chance they clinch a spot by Sunday so he'd pitch the WC and then we'd probably get Colon for Game 1. They've certainly had the hottest bats over the last week and month out of the WC options.
A couple of Cub related puzzles.
Can't teach height and thinness
Hopefully Pirates don't call up A. Lincoln.
j.buchanan going friday...should be...baseball...or something like it.
Wow. I didn't know they could do that.
Nice for Willson, not so much for Addy.
Game is officially called...also officially a tie.
Stats count, no make-up date of course.
Yeah -- seeing the weather -- I hope KB and Rizz are inside, wrapped in blankets and drinking hot chocolate.


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School students clean up river in Indian capital
08 December 2005, 17:45
by Shantum Seth
I have just returned from a wonderful Shramdaan (Volunteer effort) organized on the banks of the Yamuna where we had a symbolic cleanup of the river. Kinuko Mitani, from the UNV country office team, had sent out an invitation about this on Friday. About a thousand young people, including a lot of 'differently abled', participated from about 15 schools. A lot of enthusiasm, discussions and of course action. The Municipal Corporation of Delhi got fully involved too.
The purpose of this action amongst many others in our Volunteer Promotion Unit campaign is to build a movement in support of a clean Yamuna and to put Yamuna onto the 'Mind map' of Delhi and its citizens. For those of you who could not come, you can catch a glimpse of the volunteer action on India TV, CNBC, and some print media including the Times of India.
After the shramdaan, the young people sat by the river and enjoyed a concert by Valentine Shipley of Indian Ocean fame (the stage was on two boats). The music included some older numbers like 'We shall overcome' and 'Blowing in the Wind' which aging 'peaceniks' like me thoroughly enjoyed.
Also, for the last four years we have been encouraging and supporting a festival of street plays on volunteering and social issues. It was again put together this year by a former National UNV of the Volunteer Promotion unit, who is now working for Gandhi Smriti and Darshan Samiti.


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IACP Foundation: SELECT Scholarship Awards for Law Enforcement Family Members
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October 2008
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TRUCKEE, Calif. - The centerpiece of today's Law Review is Federal District Judge William Alsup. In a marvelous piece of creative writing, if I don't say so myself, we are combining Judge Alsup's: (1) recent Opinion partially certifying a class action lawsuit against Kmart, and (2) reviewing his superbly written historical book: "Missing in the Minarets - the Search for Walter A. Starr, Jr."
Let's do the boring stuff first - class action.
Kmart Cashiers
Lisa Garvey, who worked as a seasonal cashier in the Tulare Kmart store for a mere two months in 2010, received a letter/newsletter from a well-known attorney who represents employees suing California businesses.
Garvey subsequently hired the lawyer and sued Kmart - on behalf of all employees working in the Tulare Kmart and in Kmarts throughout California - for a violation of California Wage Order 7-2001(14). Order 14 requires that all working employees be provided with seats "when the nature of the work reasonably permits the use of seats." According to the lawsuit, Garvey's attorney has filed 14 other "suitable-seating" suits against California retailers. Her suit came before District Judge Alsup.
Class Certification
Garvey's attorney argued the suit was appropriate for class certification as there were 71 individuals employed in similar roles as cashiers at the Tulare Kmart. And, the facts were common and typical among all Kmart cashiers in California, such that the class should include all of Kmart's California cashiers. All should be able to sit on the job.
Troubling Aspect
One portion of the Opinion in particular troubled me. In support of Kmart's contention that Garvey's attorney had filed 14 other employees-must-be-provided-seats lawsuits in California, Kmart quoted parts of a deposition of Garvey's purported expert witness, who stated Garvey's attorney and "some other attorneys ... were having a discussion just batting around some ideas about, you know, different areas of law that, you know, might be developed further ... I said that the [Department of Labor Standards Enforcement] never had the resources to really enforce the seating requirements ... that it would be an area that could be enforced by private litigants."
If you believe that deposition, it certainly gives the unsavory appearance that Garvey's lawyer and others were sitting around looking for, if not concocting, litigation opportunities. That probably comes as a surprise.
Tulare Kmart
In the end, Judge Alsup ruled the Tulare Kmart cashiers (but only Tulare) could proceed in a class action to determine whether the nature of their cashier work reasonably permitted the use of seats. So, when you are next shopping at Kmart (or any similar store) if you see cashiers sitting, you'll know who won this case.
Missing in the Minarets
The other more interesting piece of writing from Judge Alsup unrelated to the Kmart case, is his book Missing in the Minarets, a gripping reconstruction of a highly publicized search for Walter "Peter" Starr, a prominent San Francisco attorney who in July of 1933 went missing after setting off solo to climb in the rugged Minarets region in the Sierra Nevada. The book includes photos from Starr's Kodak camera found at the scene. Starr wrote "Starr's Guide to the John Muir Trail and High Sierra Region."
The searchers included world class climbers like Norman Clyde who ultimately found Starr. It included the first search ever from an airplane - by a family friend and president of the Sierra Club - Francis Farguhar.
Local Connection
By the way, Starr's niece is our very own local Eddy Ancinas. I was so entertained by Missing in the Minarets that I asked Judge Alsup to speak to our local Tahoe Truckee Bar Association. He graciously accepted and recounted the fascinating story of the search. Good quick-read even if you are not a climber.
Jim Porter is an attorney with Porter Simon licensed in California and Nevada, with offices in Truckee and Tahoe City, California, and Reno, Nevada. He may be reached at email@example.com or at the firm's website www.portersimon.com.


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New Tech High School Great American Author Project
In the fall of 2011, Monroe County Public Library asked the students of Rachel Bahr's English and American Studies classes at New Tech High School to consider the "Great American Author." We were interested in getting teens' opinions about what criteria an author has to meet to be included on this rather arbitrary list, whether some authors considered great Americans have aged ungracefully or are no longer relevant, and who should be considered "great" that is not already.
For example, some of the teens in these classes read Catcher in the Rye by J. D. Salinger. While Salinger and his most famous work are considered to be American classics, a number of the teens, while acknowledging the importance of the book, did not feel it was all that relevant to their lives. The issues of identity and alienation Holden Caulfield experiences, which seemed radical in print when the book was published, are apparently so commonplace today in teens' real lives and in young adult literature in general that the book seemed out of touch to some of the students. Being a teenager has become so much more complex in the 60 years since the book's publication, that one student even wondered what Holden had to complain about!
After studying a wide variety of literary movements in American history, the New Tech students developed websites demonstrating their research, as well as book reviews of representative "Great American" titles. Their work will be used by the Library to fine tune our selection process for the Young Adult collection - Check them out!
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Live chat with a reference librarian is available whenever we are open. You can also send your question by filling out the Ask A Librarian form or send us a text at 812-TXT-4003 (812-898-4003).
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ROCKFORD — The University of Wisconsin-Madison announces local students to graduate at the end of the fall 2013 semester.
Antonio Conchas of Rockford earned a Bachelor of Science in economics; Amolee Patel of Rockford received a Bachelor of Science in anthropology, biology. William Flores of Durand earned a Bachelor of Science in chemical engineering. Rista Plate of Roscoe earned a Master of Science in psychology.
For information: wisonsin.edu.
Location, ST | website.com


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Top Definition
When one equips themself with "Hulk Hands" and then proceeds to masturbate.
Also see: Super Smashturbating
Also see: Super Smashturbating
I caught my twelve year old smashturbating with his Christmas present.
автор: The Powerhouse 7 мая 2009
Trending Now
Can you define these popular missing words?
Photos & Videos
Playing any Super Smash Brothers game by yourself.
Tony is smashturbating at home because nobody will play melee with him.
автор: slayertokey 8 февраля 2010


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CBS topped Sunday with NCAA basketball coverage, while Once Upon a Time hit a series low.CBS averaged 10.1 million viewers and a 2.4 in the adults 18-to-49 demographic for the night, thanks to March Madness overrun that delayed prime time by 45 minutes.Spring TV: Must-see new showsOnce (6.8 million, 2.1) dropped two-tenths to a new all-time low in a month. Revenge (6.1 million, 1.8) was even and Red Widow (4.5 million, 1.2) rose two-tenths.Family Guy (5.1 million, 2.6) was again the top-rated show of the night, growing two-tenths. On NBC, All-Star Celebrity Apprentice (5.1 million, 1.5) hit a season low.8 p.m.CBS: 60 Minutes / The Amazing Race 10.3million viewers (2.4 demo rating) ABC: Once Upon a Time 6.8 million (2.1)Fox: The Simpsons (R) 3.7 million (1.6); Bob's Burgers 3.7 million (1.7)NBC: Dateline 5.5 million (1.3) [7-9 p.m.]9 p.m.CBS: The Amazing Race / The Good Wife 9.4 million (2.0)ABC: Revenge 6.1 million (1.8)Fox: Family Guy 5.1 million (2.6); American Dad! 4.5 million (2.3)NBC: All-Star Celebrity Apprentice 5.1 million (1.5) [9-11 p.m.]10 p.m.CBS: The Good Wife / The Mentalist 9.2 million (1.6)ABC: Red Widow 4.5 million (1.2)
Page 2 of 2 - View original Ratings: Once Hits New Low; Red Widow Rises at TVGuide.com
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Location, ST | website.com


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The Ultimate Costa Rica Treehouse Adventure Starts on the Osa Peninsula.
CHRISTMAS week still available 20-27 Dec 2016. $500 OFF. If you were enthralled with the magic of the Swiss Family Robinson's treehouse and wish to create that same travel adventure and experience in Costa Rica, come stay in our Lapa's Nest Tree House in southern Costa Rica's Osa Peninsula.
Our 6 story treehouse rental is just a few kilometers hike from Corcovado National Park, just north of Puerto Jimenez on The Osa Peninsula. Five story wonder of exotic tropical hardwoods, bamboo and funky design surprises, is nestled in a 220-acre rainforest near Puerto Jimenez beaches. The moment you are in the tree house's shadow, you will feel laughter's spell. As you approach, your monkey grins become contagious. Imagination and rekindling begin to reign as you walk up the 45 steps of this unique canopy rental. Wrapped around a 150-foot Guanacaste tree, the design elements flow as if they were leaves on a vine. The child in you takes over and you feel safe and at home high in the canopy. In the morning, you go downstairs, pour yourself a cup of organic Costa Rican coffee, choose your favorite cushy sofa and sit back to watch the show. One by one, your new jungle friends greet you. First there are the howlers--then the toucans, scarlet macaws, hawks, falcons, and parrots until the air is filled with wildlife's jazz and dance. Everything is open air and you are a mere 10' from hundreds of titi monkeys swinging and munching their way through the forest The intoxicating scent of Ylang Ylang (the flower from which Chanel #5 is made) surrounds you as you walk below the canopy with your camera. Your kids will enjoy an up close look at nature and all its extreme oddities here in the tropics. You will hike, climb, meander down the river, swim the secret swimming pools, pick and eat furry exotic fruits. Just a few minutes away, you can swim with dolphins and enjoy fun eco tours with your family. Great restaurants and beaches in Puerto Jimenez, just 10 minutes away.
Weekly Rental Rates – 2-6 guests
• Low season / $1350 - $2050 wk.
• High season / $1850 - $ 2950 wk.
• Holidays / $3500 weekly
• Ask about 4 – 5 day rentals (offered sporadically as last minute specials to fill gaps between weekly rentals)
Your wild family of monkeys should travel to Southern Costa Rica to meet our Congo and Whiteface Monkeys, also 100's of Mono Titi's (endangered squirrel monkeys in COsta Rica- but not here at the reserve) pass by while you enjoy wildlife including; Scarlet Macaws, toucans, trogons, parrots, falcons, owls and the occasional visit from a sloth or kinkajou. You can see also Ibus, Egrets and Blue Herons along the Agujas river estuary below less than a 5 minute walk. Small dipping pool in the rain forest keeps you cool. Also secluded beaches, mangrove estuaries and, zip lines, kayaking, Gulf exploration, surfing, Organic chocolate farms close by accessible via the Osa's only paved road (paved road ends at Puerto Jimenez).
Everybody loves and enjoys fresh fruit from our organic farm, friendly staff, hiking and guided hikes through rain forest nearest Corcovado National Park. Our tree house guests post great vacation stories on Tripadvisor. Favorite eco tours include : Zip lines, canopy and dolphin tours near Corcovado National Park. Recent guests have seen Margays, White Anteaters and Agoutis and yes, even the hard to find Jaguar- with a BABY!. Goldminers still live in the area and we encourage you to support local Costa Rican conservation efforts within our community.
Central America's most luxurious treehouses, and amazing treehouse hotels on CNN can be found on The Osa Peninsula in Southern Costa Rica. Hit the link above this sentence and on page 1 scroll down a bit. There we are. But remember to hit the back button and come back here!
Costa Rica's Best Treehouse near Corcovado National Park, near remote beaches and 600+ monkeys in our private rainforest reserve.
The Osa Peninsula is the spot to avoid crowded resorts and tree house hotels. You'll find Lapa's Nest Tree house near deserted beaches of remote Southern Costa Rica. 3 or 4 bedroom eco friendly house rental in the virgin rainforest canopy and overlooking The Pacific Ocean. The ultimate Costa Rica Tree house adventure starts on the Osa Peninsula. If you are looking for complete privacy while on vacation with your family this is IT! Zip line, canopy adventures near secluded beach on the Osa Peninsula. Family Summer Fun, adventure in Southern Costa Rica, Best Tree houses for rent in Costa Rica, Eco friendly rentals with 360* of monkeys, wildlife and exotic birds. Rent with us for summer or spring vacation break. Or anytime! Once you choose your date, we assist you with car rental, eco tours, direct flights from San Jose to Puerto Jimenez, and make sure you arrive safely to Costa Rica's most bio diverse location. I pass on my agent discounts for travel directly to you.
A short walk through exotic rainforest vines and towering primary trees brings you to your river rock dipping pool built over the stream! Hiking trails on the reserve are great for early morning walks. The newly opened lagoon hiking trail is an awesome night hike with our onsite guide Gilberto. The endangered Titi Monkey (Mono Titi- squirrel monkeys)population has exploded at Sombra de la Lapa Wildlife Reserve. You'll see them pass through very early morning and later afternoon most days (except a very brief period during birthing season sometime between Jan-March each year).
Your rainforest tree house sits above tropical organic gardens with bananas, bread fruit, jack fruit, zapote fruit, mandarins, limes, ginger, sugarcane and more. Plus a fresh organic greenhouse with different organic vegetables available for you to use. The gardens attract a wide range of exotic tropical birds for bird watching in Costa Rica! Rare and endangered birds elsewhere in Costa Rica are plentiful here. Baird's Trogans, 2 varieties of Toucans, Scarlet Macaws, lots of different Tanagers, Mot Mots, rare Tinamou and 5 kinds of parrots are just the beginning so bring lots of extra memory cards for your camera. You'll need it! Staying with us at our Lapa's Nest Treehouse in Costa Rica is like writing a magic carpet through the canopy.


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There they were, more than two hours past the time allotted for their shopping odyssey, on a corner in Vienna, Austria. There was no sign of the tour group they had been traveling with. Each direction they could choose to walk looked pretty much as unfamiliar as the others.
About Florence
Age: 95Occupation: Retired teacher.Community: Mount Pleasant.People will remember: Her devotion to teaching and her quiet and cordial manner.Affiliations: Olive Branch AME Church; East Cooper Chapter No. 365, Order of the Eastern Star; and Alpha Kappa Alpha Sorority. Survivors: Daughter Rosalind Rivers; granddaughters, Faith Rivers James (Perry) and Angel Payton-Harmon; great-grandchildren, Haley and Terence Harmon, Jr.; and sister-in-law, Mary Alice Bostic.
The two women, who met as teachers four decades before at Jennie Moore Elementary School, stood baffled. They found the police and attempted to share their plight, but the officers couldn't speak English.
Later, a woman who spoke English encountered them and directed them back to their hotel. There they reconnected with the Alpha Kappa Alpha Sorority group they were traveling with. That and other details are part of a wonderful story, a memorial to the friendship between Florence Bostic Brown and Ruth Singleton Middleton, begun in the 1950s when they taught at Jennie Moore.
Brown, who was born Dec. 11, 1917, and died Dec. 16, would sit during breaks at school and share her strategies for reaching the first-graders she was so dedicated to starting out on a firm educational foundation.
An awesome teacher
Middleton describes her as an "awesome" teacher. "You did not come to her class and say you did not bring your homework," Middleton says. "If it happened once, it would not happen a second time. She worked with her students one-on-one and kept in touch with their parents. She would make sure parents knew what was going on. There were phone calls and conferences with parents. They would come by after school and to the PTA meetings."
Others who knew Brown agree that she was quite a teacher. Quite a person, too.
"She was a very good teacher, very poised, kind and quiet, but no foolishness," says Amelia Taylor of West Ashley. "We went to Jennie Moore when the school first opened. She was a lovely person, always cordial. But when she came to school, she came to work."
Words like "charming, quiet and ladylike" come to mind when Cynthia McCottry-Smith hears Brown's name.
After Brown graduated from Laing High School in Mount Pleasant, she joined McCottry-Smith and others at the Avery Normal Institute for teacher training before going on to earn her bachelor's degree at Allen University. "She was always just a nice, nice, caring person, quiet and ladylike."
"Reading was her baby," says daughter Rosalind Rivers. "But she was also was very strict on handwriting and letter formation. They don't do that any more."
After teaching 42 years in the Charleston County School District (Santee, St. Stephen and Mount Pleasant), Brown retired in 1983. In addition, she taught Sunday school at Olive Branch AME Church on U.S. Highway 17, where she was a lifelong member.
During retirement, Brown taught adult education classes at Wando High School and tutored children in the community. She also tutored two members of her own family for years, until she was 93.
Other interests
Those privileged to know her outside the classroom learned other things about her as well.
The small-framed woman loved the small pillbox hats, a style made famous by Jacqueline Kennedy, says Rivers. She also loved feathered hats, especially a beige one featuring lavender flowers and feathers. A couple of her hats are completely feathered.
Brown experimented with growing all types of flowers, including tulips, daffodils and roses, Rivers says.
She'll long be remembered for driving friends and neighbors on errands around Mount Pleasant in her late 1990s Mazda until she was 93, says Rivers. Many of the 35,000 miles on the car when Brown decided to give up driving were added doing things to help others.
She was strict about academics, but interested in seeing the whole child develop as well, says Rivers. That's why she would get so excited about May Day celebrations where the students would help to plait the Maypole each spring.
"She was awesome," Middleton says. "She always wanted the best. She was driven in that direction. She carried herself that way."
Reach Wevonneda Minis at 937-5705.


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on February 1, 2013 - 12:24 AM
Except for perhaps Andrew Lloyd Webber, musical theater composer Stephen Schwartz is responsible for inserting more ear-worms into young heads than any other practitioner of the form.
Take, for instance, all those catchy numbers from 1971's "Godspell," with its seemingly endless litany of hummable melodies. Then there's the similarly addictive "Pippin," followed up by a dizzying array of hook-laden numbers from "Children of Eden" and, of course, Schwartz magnum opus "Wicked."
Kaleidoscope Theatre Productions will present an original revue of Schwartz tunes in "A Night With Schwartz." The show, which opens tonight in the company's home in the Lecture Hall Theatre in the main building of Medaille College (18 Agassiz Circle), was written and developed by Kaleidoscope's Beth A. Gerardi-Wharton, Thea Fenton Wheeler and Keith Wharton.
The show features more than 20 of Schwartz's songs, along with the Western New York premiere of "Testimony," his choral arrangement written for Dan Savage's popular "It Gets Better" campaign. Appearing in the show are Gerardi-Wharton, Bethany Burrows, Robert "Ernie" Insana, Kelly Kroese, Melissa Leventhal, Christian Riso, Mary Ryan and Shawn William Smith.
Tickets to the show, which runs through Feb. 16, are $13 to $20. Call 479-1587 or visit www.kaleidoscopebuffalo.com.
– Colin Dabkowski


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Digital Storytelling
Summary Form
Due: April 1
Digital Story Title:
Understanding Sonata Form: A Case Study
Brief description:
Using musical excerpts, live performance, interactive components, and comedic dialogue, this video explores sonata form using the first movement of Dittersdorf's "Concerto for Double Bass and Orchestra in E Major" as a case study.
Main goal(s):
Encouraging active listening, interpretive imagination, and an understanding of sonata form, one of the most ubiquitous classical forms of the nineteenth and twentieth century.
Who is your intended audience? (e.g., colleagues, historians, art historians, the general public, high school history students, middle school music students, art students. . . )
My intended audience is uninitiated classical music listeners over the age of 14.


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Englewood, CO – Swedish Breast Care Program In Partnership with Invision Sally Jobe Breast Center has been granted a three-year/Full accreditation designation by the National Accreditation Program for Breast Centers (NAPBC), a program administered by the American College of Surgeons.
Accreditation by the NAPBC is only given to those centers that have voluntarily committed to provide the highest level of quality breast care and that undergo a rigorous evaluation process and review of their performance. During the survey process, the center must demonstrate compliance with standards established by the NAPBC for treating women who are diagnosed with the full spectrum of breast disease. The standards include proficiency in the areas of: center leadership, clinical management, research, community outreach, professional education, and quality improvement. Through this NAPBC accreditation the Swedish Breast Care Program In Partnership with Invision Sally Jobe Breast Center has demonstrated a firm commitment to offer its patients every significant advantage in their battle against breast disease.
"This accreditation is exciting because it really brings attention what we have believed in providing for our patients all along – the highest quality care with the best possible outcomes," said Jane M Kercher, M.D. "Our Breast Center is collaborative right from the point of diagnosis, into treatment and survivorship. We work together to provide the region with an unparalleled continuum of quality care."
The NAPBC is a consortium of professional organizations dedicated to the improvement of the quality of care and monitoring of outcomes of patients with diseases of the breast. This mission is pursued through standard-setting, scientific validation, and patient and professional education. Its board membership includes professionals from 20 national organizations that reflect the full spectrum of breast care.
The American Cancer Society (ACS) estimated that there would be 232,340 patients diagnosed with invasive breast cancer in the United States in 20131. In addition, hundreds of thousands of women who will deal with benign breast disease this year will require medical evaluation for treatment options.
Receiving care at Swedish Breast Care Program In Partnership with Invision Sally Jobe Breast Center, a NAPBC-accredited center ensures that a patient will have access to:
• Comprehensive care, including a full range of state-of-the-art services
• A multidisciplinary team approach to coordinate the best treatment options
• Information about ongoing clinical trials and new treatment options
And, most importantly,
• Quality breast care close to home.
For more information about the National Accreditation Program for Breast Centers, visit their Web site at http://www.accreditedbreastcenters.org.
1. American Cancer Society Cancer Facts & Figures 2013. Atlanta: American Cancer Society; 2013


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Wednesday, August 20, 2014
The South Carolina Highway Patrol made an arrest Thursday, Aug. 21, in a hit-and-run fatality Tuesday, according to SCHP and Berkeley County Sheriffs officials.
Terry Walter Erdman II, 32, of Cross, was taken into custody just after 5 p.m. by state troopers and taken to the Berkeley County jail.
Peggy Ann Cain, 59, was found on Trojan Road in Cross at 10 p.m. Tuesday, Aug. 19. She was taken to a local hospital, where she was pronounced dead.
Erdman is charged with leaving the scene of a collision involving death. Officials said a bond hearing was set for later Thursday.
A traffic stop was made on Shortcut Road off S.C. 45 on Thursday afternoon when a highway patrolman spotted a white Chevrolet minivan with missing parts that matched evidence found at the scene.
Erdmans girlfriend was driving the van at the time of the stop. She advised officers where he was located, and he was then was taken into custody from his workplace.
He also had warrants for his arrest for other violations from the Berkeley County Sheriffs Office.
Autopsy results on Cain are pending.
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