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LC-MS Gains Favor Due To the...
Wall Street Decline Takes Its Toll...
NSCLC is "Major Battlefield" as Merck,...
As Immunotherapy Revolutionizes the Cancer Treatment...
With an estimated 90% of lead candidates from in vitro screens ending up as also-rans—despite the spiraling costs of development—new ways of eliminating these candidates earlier in the drug discovery process need to be developed. A major theme running through Visiongain's recent London-based "Cell Based Assays" conference is that while current tests are good at picking up blatant red flags such as carcinogenesis and necrosis, they can be nearly colorblind to the shades of pink represented by heart arrhythmias and the accumulation of toxic metabolites, for example.
"The holy grail of early-stage drug discovery is the subtleties in and around toxicity that really kills programs—it's not overt cell death," noted Quin Wills, CSO and co-founder of SimuGen.
The screens for more subtle toxicities—where they exist—tend to be more time- and labor-intensive, and are often relegated to use on later-stage candidates in which substantial resources have already been invested. "In pharma there is a great desire to move to assays using primary cultured cells farther upstream in screening cascades," said Steven Shamah, director of cell biology for SRU Biosystems. Thus, there is a need for high(er)-throughput cell-based methods that can say more than just that the cell is dead.
Sometimes the bottleneck in cell-based screening is the availability of the high-quality cells themselves. "Even when pharma does have the opportunity to use human primary cells, they end up with cells that are of highly variable composition, quality, from different donors at different ages, with different underlying morbidity, environmental influences, postmortem intervals, and a number of variables that they can't control," pointed out Stephen Minger, GE Healthcare's global director of R&D for cell technologies.
To address this issue, GE Healthcare acquired the rights to develop Geron's (www.geron.com) human embryonic stem (HES) cells for the nonclinical research market. HES cells are highly stable and can be grown to unlimited numbers in culture. "They represent a tremendously valuable source of cells where you can provide a consistent quality of cells with a consistent genetic background, week-in, week-out," Minger says, "that could, in principle, give rise to every type that pharma might want to use for their safety studies or even in primary drug discovery."
Minger and his team differentiate industrial-scale quantities of HES cells into highly functional populations of human cardiomyocytes, which have been characterized developmentally, morphologically, biochemically, and functionally, and have been validated both internally and externally. The cells were screened against large panels of compounds that are known to interfere with action potentials, and were found to be equal to or better than current FDA-mandated safety tests. "In some cases," he added, "they're predictive when the standard animal tests are not in picking out long QT [delayed repolarization]."
GE Healthcare is developing a range of assays that, when combined with their capabilities in high-content imaging, can look at both the population and individual cell level for compounds that interfere with both electrophysiological properties and with subcellular organelles like the mitochondria and membrane integrity. Ultimately, they are trying to develop a whole range of cell types—HES-derived hepatocytes are already in the pipeline—with broad genetic diversity gained from utilizing cells from national banks. "Now, all of a sudden, you almost have a Phase I in a dish."
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Top Definition
Buying tons of Holiday items(Mostly Food)to enjoy after the holidays are over. This does not only apply to Christmas, but any other commercialized holiday.
"Mom just went shopping, and she is definately going to be holiday hoarding some Christmas cookies. We're gonna end up eating them until mid-July.
ayon kay Your Moms Man ika-28 ng Nobyembre, 2010
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Can you define these popular missing words?

subset: commoncrawl


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Eagles Resort
The Eagles Resort is always a huge hit with families because of its prime location directly opposite the village centre and excellent access to the beginner and night-skiing slopes. Inside guests will appreciate the large rooms, convenient layout, comfortable furnishings and excellent Monashee mountain views. Kids of all ages will love the pool-sized outdoor/indoor hot tub and there is also a sauna and games room available.
|Common Sauna & Hot Tub
|Communal Laundry
|Non-Smoking Rooms
|Outdoor Parking
|Ski Lockers
|Ski-in/Ski-out Access
|Underground Parking
|Wheelchair Accessible
|Lite Service, with a Full Service clean on the 3rd or 5th day depending on length of stay
|Common Games Room with Free Nightly Kids Events
|Free Wireless Internet Access
|Common Outdoor Hot Tub, open daily from 2-10 pm
Individual Rooms
|3/4 Bdrm Regular
Central Reservations
Toll Free: 1.800.663.2772
Local Phone: 250.765.8888
Email: email@example.com


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This is your chance to win a pair of tickets to Fort Peck Theatre, airfare for two, courtesy of Cape Air, transportation to the theater and one night stay at the Historic Fort Peck Hotel! These tickets are good for the below listed theatrical acts.
No purchase is necessary to enter this promotion.
Entrants must be at least 18 years of age.
Good luck!Congratulations to our winners!
Sharon Oakland
Chris Field
This contest is brought to you in part by
Contest: YBS Draw Cape Air
Date: July 24, 2014 – July 31, 2014
Prize/s: Pair of tickets to Fort Peck Theater ($17 per ticket), airfare for 2 courtesy of Cape Air (value $104 per person), transportation to the theater and one night stay at the Historic Fort Peck Hotel (value $87)
Number of Prizes: 2 (Two)
Go to YourBigSky.com and click on the Cape Air giveaway icon to register to win a pair of tickets to Fort Peck Theater, transportation to the theater, one night stay in the Historic Fort Peck Hotel and airfare for two courtesy of Cape Air! Registration opens Thursday July 24th, 9:00AM and closes Thursday July 31st, 8:00AM. All winners will be drawn July 31st by 9:00AM and posted on YourBigSky.com. A total of two packages valued at $329 each will be given away.
No purchase is necessary to enter this promotion.
Entrants must be at least 18 years of age.
The promotion is open to US residents residing within the KSVI/KHMT DMA except employees of KSVI/KHMT, YourBigSky.com, Nexstar Broadcasting, Inc., Mission Broadcasting, Inc. (collectively, the "Stations"), employees of other television and radio Stations in the KSVI/KHMT DMA, the affiliates, subsidiaries, advertising or promotion agencies (if any) of all of the foregoing, and members of the families or persons living in the same household of all of the foregoing.
Limit of one prize per household. Register once per day.
Odds: The odds of winning depend on the number of entries submitted.
By participating in the promotion, all participants, including winners, agree to have their name, voice, or likeness used in any advertising or broadcasting material relating to the Contest, without any further compensation from the Stations, YourBigSky.com or participating businesses. Winners agree to sign a publicity release, affidavit of eligibility and release of liability prior to receipt of the prize. By accepting the prize, each winner grants to Stations, YourBigSky.com and any sponsors the right to use the winner's name, voice, picture and/or likeness for purposes of advertising and publicity in any and all media now known or hereafter invented, without further permission or additional compensation (except where prohibited by law).
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Winners will be required to provide photo identification to claim their prize.
Prize can be claimed at KSVI ABC 6/KHMT FOX 4 at 445 South 24th Street West, Monday through Friday, 8A-5P. Prizes not claimed by Friday, August 15th, 2014 by noon will be returned to prize inventory.
Each winner is responsible for all federal, state, and local taxes and will be required to complete an IRS form W-9, as requested. Winner will be required to provide a valid Social Security Number and a copy of a current government-issued photo identification in such form as requested by YourBigSky.com and will be required to execute an affidavit of eligibility and liability release form before the prize may be claimed.
All expense on receipt and use of prize are the sole responsibility of winner. Winner by acceptance of their prize, releases YourBigSky.com, it's advertising, promotion and production agencies and the respective parents and subsidiaries, shareholders, directors, employees, agents and representatives of the foregoing from any and all liability, claims or actions of any kind whatsoever for injuries, damages or losses to persons and property which may be sustained in directly or indirectly in connection with the receipt, ownership or use of the prize or while preparing for, participating in, and/or traveling to any contest or prize-related activity.
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A semi-private school in Newcastle, Maine. Located right beside downtown Damariscotta, so that kids can just skip school and walk right past any cameras they have. Usually filled with stoners and whores, sometimes a mix of both in the same child.
"I went to Lincoln Academy" - mom
"Oh. That's why I don't know who my dad is"
"Oh. That's why I don't know who my dad is"
de ShaunaMariee 22 Octombrie 2008
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A semi-private school in Newcastle, ME. A pretty nice school with a lot of really smart and fun people. Really it only has three problems: the guidance and development offices are incompetent, the band has to play in a basement and people write rude things about our fine school.
"Lincoln Academy is a fine place to go to school."
"Lincoln Academy's band is better than it's chorus."
"Lincoln Academy's band is better than it's chorus."
de hytuqwer 02 Aprilie 2010


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Organ Trail Final Cut Expansion
Hey everyone!
Organ Trail is getting a huge update on October 20th with the Final Cut Expansion. You can read more about it on our blog: http://hatsproductions.com/blog/2015/organ-trail-complete-edition/
But what I'm most... Read more
Steam Launch Date, Indie MEGABOOTH & New Game
It's official. Our launch date for Organ Trail: Director's Cut on Steam is March 19th. You can see the store page up right now. http://store.steampowered.com/app/233740/ Right after we launch we... Read more
We are in Contests!
We are in 3 public voting contests right now. If you like us, you can show it by sending a few clicks and maybe some retweets or something our way.... Read more
Why I am (and you should be) happy our Greenlight campaign failed.
Just to give you spark notes on what has been happening over here...
- Aug 9th - We released the iOS and Android version of Organ Trail: Director's Cut.
- Aug 30th-... Read more
New Content! (sorta)
There is no time to explain! If you want to see awesome new stuff in Organ Trail: Director's Cut, go here and watch the short video: http://www.hatsproductions.com/organtraildc/greenlight.html
Please help us and... Read more
Greenlight is Go!
That title seems redundant. Anyway. Go to the following link and upvote us if you want to see Organ Trail on PC/Mac! (And even if you don't, I would appreciate... Read more
Steam Greenlight and PAX Prime Updates
Big stuff happens tomorrow.We have two announcements to make so be sure to check back. One is the launch of our Steam Greenlight page. The long and short of... Read more
PC/Mac and Steam Greenlight
So it appears that Steam is no longer accepting submissions for games until the 30th due to Steam Greenlight.
Although we can release through other platforms, my grand vizier tells... Read more
Mobile Launch!
The game is live for mobile!
Okay we are doing this Chicago mafia style. If you share this link with all your friends, I owe you one. If you... Read more
iOS and Android Release Tomorrow
Whooo I'm so nervous I might throw up.
Game will be out tomorrow.
Backers: I will be buying individual copies to gift out for those of you that get the... Read more
Finishing & PAX
We are now transitioning away from touching the game to building materials for release. We have a potential release candidate in our playtesters' hands right now.
Touch Arcadedid a... Read more
In BETA
Quick update: We are currently playtesting the game. The feature list is super small and I'm tackling bugs as they come in. So everything is on track. (Other than always... Read more
Getting There
So the game's end is finally in sight. I wanted to drop by and update you guys on how things look on our end. This is somewhat development heavy so... Read more
Screenshot Update
I'm on a roll today but I thought you all might enjoy me dropping in and sharing a few screenshots I took while working.
I Quit My Job
I am now, officially, a full time independent game developer. Today is my first day. Let's start with a happy image.
The Men Who Wear Many Hats started out as a bunch... Read more
PAX East
I don't even know where to start. I'm still sort of letting that weekend set in. I guess I will start by saying that I loved it. I finally feel... Read more
Two Awesome Organ Trail Images
First up, here is a pile of most the rewards, as we divide them up for PAX East and for shipping.
Next up, a great last-minute piece of art by... Read more
It Runs on Everything!
Hey look! We have the latest build of the game running on all promised platforms! This latest version has brand new UI, some of the new music we've been getting... Read more
The $500 Backer Designs
Hey everyone who is attractive and generally keen. After a bit of radio silence, we've got a lot of stuff incoming so keep an eye out for updates on development... Read more
Final Hours and Poster Design
39 hours to go and we are well on our way to quintupling our goal and reaching 15K. Special thanks to the press peoples that have been nice enough... Read more
Quick update! We couldn't decide between two ideas for the limited edition shirt. So we just did both! Here is an image with the designs:
Hope you guys like em.... Read more
One Week Left - Postcard Update
We have one week to go and I think we are doing pretty well considering we have almost quadrupled our asking amount. I would personally like to thank you, the citizens of... Read more
Android and iPad
No time for a cool update with photoshop'd pictures.
We reached 5k! I'll be updating the stuff later today but we will add an Android and iPad version of the... Read more
Halfway Mark and Wallpapers
Happy new year and all that.
Let's get to the good stuff. First of all is free wallpapers for all!
I made about 12 sizes of wallpapers in two variants of our... Read more
Victory and new rewards
I'm Glad to announce that we have reached our goal of $3,000, 60% of which was in the first 24 hours. Next up, we want to reach $5,000 so we... Read more
Seasons Greetings + Blooper Reel
It's a [all-inclusive winter holiday] miracle! We've managed to reach 65% of our goal in under two days! That's freaking insane. Thank you so much for your holiday love (and... Read more


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Top Definition
A term coined in New York, pfnsht is like saying "bullshit" but without sounding stupid and uneducated. It is really "Puffin Shit" but when slurred you get this all-purpose swear word no-one will call you on.
A: Our teacher is nice.
B: Pfnsht, yeah right.
B: Pfnsht, yeah right.
Beküldő: miketaba 2005. szeptember 24.
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Can you define these popular missing words?


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Inside city hall it is a wait and see moment these days for the man who by most accounts will be Detroit Mayor Dave Bing's pick to be the new fire commissioner.
The appointment of Donald Austin, who is from Los Angeles, California, where he served as assistant chief of fire department there, is expected be announced by Mayor Bing soon. If appointed, Austin will be bringing almost three decades of experience to the city's fire department. This appointment is significant for the city of Detroit in light of not only the recent census numbers, but the less than desired services residents and businesses have been receiving from the Detroit's Emergency Medical Services (EMS) which operates under the Detroit Fire Department.
Even though the fire commissioner is basically an administrative role because the chief of fire operations handles fire operations in the city, the leadership of the department mirrors the kinds of services those are being encouraged to stay and do business in the city will receive.
And everyone has a reason to be concerned about the slow EMS response that has been blamed on everything else including trucks that are not working.
But no one really called for a surgical operation of the department. The problem of EMS is beyond non-workable equipment. It speaks to serious managerial issues and what kind of resources should be devoted to ensure that people who are in need of medical attention get to the hospital on time.
To do so will require leadership at the fire department that has vision.
One individual who is very with fire department operations told me Tuesday morning that "the fire department's problem is that it never had a business model to operate from in the first place," which explains half-baked EMS service that has been publicized for all to see. "The challenge now for the new fire commissioner when he gets in town is to ensure there is no more death when EMS is called to a home," the individual said.
I don't know Donald Austin. But his first task would be to take a serious look at EMS and get to the root of the problem and let taxpayers if, in fact, the problems hinge equipment and not management.
Detroit is in a crucial economic and political state and our leaders cannot talk about attracting businesses and families to the city when response time from EMS is slow.
Anytime there is an incident at a home and EMS doesn't show up on time, it's a minus for the city because its insurance risk of doing business goes up. Businesses take that into consideration before moving into a particular area.
The Insurance Services Organization (lOS), which rates municipalities and cities on insurance risk issues dealing with EMS, fire, etc., has a record on Detroit. But its corporate office in New Jersey, according to spokeswoman Jessica Riccardi, would not release the city's latest insurance risk rating, noting that such records are kept with the fire department.
A fire officer who requested anonymity because he has not been authorized to disclose any information, said the city's rating is not that impressive given the wave of dismal services we have seen with EMS.
Couple that with the Census and Detroit should now be thinking outside the box — how to address the needs of taxpaying residents and businesses in a tough economy.
If Donald Austin is the man to lead the fire department, he will have to work out a plan and set a vision for the department that has an annual $175 million budget. With that amount the city cannot afford to have a slow ambulance system that is currently forcing people to think twice about staying in Detroit.
The city has a notorious reputation for not accepting outsiders leading powerful institutions that make up its local government; so Austin will have to stand firm.
The fire department should not repeat the mistakes of former Detroit police chief Jerry Oliver who butted heads with the men and women in blue.
Instead, a new fire department leader should assemble a team that will revamp everything from equipment to management. Take action that will give the public, confidence that we are in safe and competent hands.
Give families who are struggling to keep their mortgages and pay their taxes a reason to live here and feel confident that the next EMS· response time will be swifter than the last.
Demonstrate to businesses that Detroit is a world class city, and that means core services are provided without delay or administrative bureaucracy.
How the Detroit Fire Department fares after Bing announces his pick to lead the troubled department will say a lot about emergency preparedness in the city. It will show the world whether Detroit gets it.
Those hard-working fire fighters out there in the streets and EMS workers should not have to be strangled and made to take the fall, when the real problem is leadership, resources and management at the helm of the department.
Make Detroit proud by changing the game.
Bankole Thompson is the author of the new book, "Obama and Black Loyalty, Vol. 1," part of a trilogy on President Barack Obama. Listen to his weekly analyses Thursdays at 11:15 a.m. on "The Craig Fahle Show," WDET-101.9FM, NPR affiliate. E-mail him at email@example.com.


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Are any tailgating foods good for you?
POSTED: 9:46 PM PST December 28, 2011 UPDATED: 9:07 PM PST January 19, 2015
For some, the best part of football season is what happens outside the stadium. But which foods are best and worst for your body?
The views expressed are not those of this company or its affiliated companies. Please note by clicking on "Post" you acknowledge that you have read the Terms of Service and the comment you are posting is in compliance with such terms.


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5 Revenge Products: A Buyer's Guide for Psychopaths
Are you sick of product reviews that don't cover the issues that matter to you? Most product review sites are all "reliability this" and "functionality that," when all you really want to know is "Will this product assist me in fulfilling an elaborate and lifelong revenge mission?" Well, finally, I'm here to supply you with the answers you need. Today, we're going to profile five products for the discerning modern psychopath. Our review will take place in two parts: First, an introduction and quick rundown of each product, then a practical real-life field test where I will attempt to use each one to help unleash my cunning vengeance on an unsuspecting world. First up, product breakdowns!
#5. Singing-Bird Pistols
Revenge, especially of the "burning" and "eternal" variety, is not a cheap venture. There's no such thing as vengeance on a budget. Justice deserves the best, and that's what you'll get here: These Singing-Bird Pistols are a one-of-a-kind item, manufactured by master craftsmen at the esteemed Freres Rochat workshop. They're constructed of solid gold, inlaid with pearls and diamonds, and they come complete with a set of singing-bird automatons that kick into motion with every pull of the trigger. This is the only known matching set in existence, and as such, you can expect to pay about $5 million for the classiest murder weapons in history. It ain't cheap, but a long-anticipated gentleman's duel with Gary Woobarth, the bastard who told your teacher that you were trying to break into the monkey enclosure on your fifth grade field trip, is a once-in-a-lifetime thing.
#4. Caffeinated Beef Jerky
Vengeance is exhausting: all the plotting and manipulating, the setting of cogs in motion and disposal of witnesses -- did you know that pure, unbridled hatred burns more calories per hour than a light run? Even when you're just sitting there, doing nothing but fuming over past injustices, that's the caloric equivalent of jogging. All the time. You need energy, but drugs cloud the mind, and caffeine is lacking in that visceral appeal, somehow. You never see Dr. Doom downing a Red Bull to get the pep he needs to hurl Reed Richards into a pit of robotic Doom-spiders. But I think I have the answer for your furious energy needs: Perky Jerky!
Don't let the name throw you. There's nothing "perky" about this product. This is dried, withered meat -- much like your angry, dead heart -- infused with chemicals that give you unnatural energy -- much like the fury that drives your every waking moment. Feeling sleepy? Don't brew a cup of coffee, like a chump: Tear into the flesh of another living thing and start your villainous morning right. Since Perky Jerky, like revenge, is best bought in bulk, you probably want to skip the bags and go right for the Jerkman Suit.
Nothing strikes fear into the hearts of those who've wronged you like draping yourself in armor forged from desecrated animal corpses, and unlike the Singing-Bird Pistols, the Jerkman Suit will only run you $350. Practical, budget-friendly, and blasphemous: It's a great investment for the first-time justice seeker and the seasoned spirit of vengeance alike.
#3. The Octopus Throne
Image is incredibly important in the field of long-term revenge missions. You don't want to spend decades enacting a flawless plan of clockwork intrigue only to finally confront your betrayer from some cheap plastic IKEA chair. The Fludocken, while ergonomical and budget-friendly, does not exactly scream "You have come to me to meet your much-deserved end." To rule a kingdom of woe, you need an appropriate throne. Enter, the Octopus Chair:
Designed by Maximo Riera, who simply must understand vengeance with a name as flamboyant as that, the Octopus Chair is the first piece in a whole line of evil animal-themed furniture. And what better way to visually illustrate that Gary Woobarth will never escape the long-reaching tendrils of your wrath than the grasping onyx tentacles of the giant black octopus? Pair it with a lovely Blood Rhino Armoire and a couple of tastefully understated Ash Spider End Tables to complete the look!


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Hamilton College considers the opportunity to transfer credit from study abroad a privilege, not a right. You must meet certain requirements to be eligible to receive credit for study abroad.
You must fulfill the requirements above to be eligible to transfer credit to Hamilton College from study abroad. Study abroad programs to which you may apply may have higher GPA or language requirements for admission.
With some planning, most students can make study abroad mesh with their larger academic plans. Find out how you should prepare to fill your concentration requirements before and during study abroad.


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Wednesday, January 23, 2013
There's nothing wrong with a good, old-fashioned thriller.
Especially if you are fortunate enough to come out on the winning side, like St. John's Christian Academy's boys basketball team on Jan. 15.
After being down by 17 points at the half the Cavaliers came to life in the third quarter and pulled out an overtime thriller 80-78 against Ashtree Learning Center.
"It was a high quality high school basketball game," said St. John's coach Bob Winters. "Ashtree came in 14-1 and have a couple of at least mid-major college prospects. They were big (6-7, 6-4, and 6-3), fast, athletic, and had good basketball skills."
A 20-point third quarter spurred the Cavs comeback.
"There is a purposefulness to the way I schedule games and this was a team that would have trounced us in early December," Winters said. "I wanted to assess our progress to date and was pleased with our effort, competitiveness, intelligent play and ability to make plays down the stretch with the game on the line."
The Cavalier defense limited Ashtree Learning to just 22 second half points before the overtime period while the offense poured in 39 points to tie the score at the end of regulation.
"We are maturing into a good team," the coach said. "Mike Lewis, Damian Hurta and Jalen Ward led us offensively with Bobby (Winters) chipping in nine assists on some big time passes."
Lewis led SJCA with 27 points while Hurta poured in 23 points and Ward 16 to lead the Cavaliers.
Ashtree's Marcus Brown led all scorers with 35 points.
Greg Gamble played big in the paint with 11 points, 15 rebounds and seven blocked shots, including a pair of monster slam dunks according to Winters.
"All of our guys stepped up and played tough, hardnosed, aggressive basketball," he said. "We came back from 17 down at the half, kept our foot on the gas, but never panicked or got in a hurry. Ashtree made some really tough shots but we just stuck to our plan and it paid off.
"I am really proud of our guys."
SJCA improves to 11-4 and 4-0 in region play. Ashtree falls to 14-2.
The Cavaliers were to play Coastal Christian Academy on the road on Friday.
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Robert Pattinson Wanted to Put Walruses in Breaking Dawn Sex Scene
But if it were up to Robert Pattinson, who plays Bella's husband Edward Cullen, the bedroom action would get even wilder.
"I would put [the sex scene] the last day of the schedule," he told BBC Radio 1 of his fantasy turn in the director's chair. "[I'd] say, 'Listen, I've got to have a closed set. It's really, really important. No one can see the monitors or anything,' and then just put like a walrus in or something."
Jokes aside, it's not so sexy puckering up in front of the cameras.
"Kissing is harder than love-making scenes, I think," Pattinson, 26, says. "You can't kiss like normally you'd kiss."
Adds The Twilight Saga: Breaking Dawn – Part 2 star, whose movie arrives in theaters Friday: "You got a one in three chance of smashing someone's tooth out."


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Microsoft Dynamics AX 2009 – Using Record Context in Enterprise Portal
- Posted: Jun 25, 2008 at 12:36PM
- 1 comment
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Hello and welcome to another Microsoft Dynamics Ax 2009 Enterprise Portal screencast.
Microsoft Dynamics AX developers will learn how to use record context in Enterprise Portal. Record context is used to pass currently selected record information on a page or Web part to another page or connected Web part.
This how-to-video demonstrates three ways of passing record context:
Use a Microsoft Dynamics AX hyperlink field to link to a detail page for the selected record. In this method, the context is passed automatically to the detail page, and no coding is required. Use an ASP.NET template field to link to a detail page for the selected record. In this method, you must pass the context through code.
Use Web parts that are connected to display the list and the details on a single page. When you click on a record in one Web part, the context is automatically passed to the second Web part.
Enjoy the show!
Mey Meenakshisundaram
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The Consumer Product Safety Commission (Commission or CPSC) has received a petition requesting an exception from the 100 ppm lead content limit under section 101(b) of the Consumer Product Safety Improvement Act of 2008 (CPSIA), as amended by Public Law 112-28 from BIC USA Inc. (BIC). We invite written comments concerning the petition.
Submit comments by May 30, 2013.
You may submit comments, identified by Docket No. CPSC-2013-0016, by any of the following methods:
Electronic Submissions: Submit electronic comments to the Federal eRulemaking Portal at: http://www.regulations.gov. Follow the instructions for submitting comments. The Commission does not accept comments submitted by electronic mail (email), except through www.regulations.gov. The Commission encourages you to submit electronic comments by using the Federal eRulemaking Portal, as described above.
Written Submissions: Submit written submissions in the following way: Mail/Hand delivery/Courier (for paper, disk, or CD-ROM submissions), preferably in five copies, to: Office of the Secretary, Consumer Product Safety Commission, Room 820, 4330 East West Highway, Bethesda, MD 20814; telephone (301) 504-7923.
Instructions: All submissions received must include the agency name and docket number for this notice. All comments received may be posted without change, including any personal identifiers, contact information, or other personal information provided, to: http://www.regulations.gov. Do not submit confidential business information, trade secret information, or other sensitive or protected information that you do not want to be available to the public. If furnished at all, such information should be submitted in writing.
Docket: For access to the docket to read background documents or comments received, go to: http://www.regulations.gov, and insert the docket number, CPSC-2013-0016, into the "Search" box, and follow the prompts.
Kristina Hatlelid, Ph.D., M.P.H., Directorate for Health Sciences, Consumer Product Safety Commission, 5 Research Pl, Rockville, MD 20850; email: firstname.lastname@example.com; telephone: 301-987-2558.
Under section 101(a) of the CPSIA, consumer products designed or intended primarily for children 12 years old and younger that contain lead content in excess of 100 ppm are considered to be banned hazardous substances under the Federal Hazardous Substances Act (FHSA).
Section 101(b)(1) of the CPSIA provides for a functional purpose exception from lead content limits under certain circumstances. The exception allows the CPSC, on the Commission's own initiative, or upon petition by an interested party, to exclude a specific product, class of product, material, or component part from the lead limits established for children's products under the CPSIA if, after notice and a hearing, the Commission determines that: (i) The product, class of product, material, or component part requires the inclusion of lead because it is not practicable or not technologically feasible to manufacture such product, class of product, material, or component part, as the case may be, in accordance with section 101(a) of the CPSIA by removing the excessive lead or by making the lead inaccessible; (ii) the product, class of product, material, or component part is not likely to be placed in the mouth or ingested, taking into account normal and reasonably foreseeable use and abuse of such product, class of product, material, or component part by a child; and (iii) an exception for the product, class of product, material, or component part will have no measurable adverse effect on public health or safety, taking into account normal and reasonably foreseeable use and abuse.
Under section 101(b)(1)(B) of the CPSIA, there is no measurable adverse effect on public health or safety if the exception will result in no measurable increase in blood lead levels of a child. In November 2012, CPSC staff issued a report, which found that, for the purposes of evaluating children's products for an exception from the CPSIA lead limit, a product will have no measurable adverse effect on public health or safety if a potential exposure to lead from the product is estimated to result in an increase in a child's blood lead level of less than 0.8 µg/dL. The level of exposure that would be associated with such an increase is approximately 2.2 µg per day. That report may be viewed at: http://www.cpsc.gov/PageFiles/133902/lead101.pdf.
Given the highly technical nature of the information required for an exception, including data on the lead content of the product and test methods used to obtain those data, the Commission finds that notice of the petition and solicitation for written comments would provide the most efficient process for providing an adequate opportunity for all interested parties to participate in the proceeding. However, the Commission may hold a public hearing or public meeting if the Commission deems a public hearing or public meeting appropriate and necessary to determine whether the petition for a functional purpose exception should be granted.
On March 25, 2013, BIC submitted a petition requesting an exception from the lead content limit of 100 ppm under section 101(b) of the CPSIA for a new line of writing instrument products aimed at children age 5 and up (BIC Children's Pen) to address the needs of young children who are in the early stages of learning to write. BIC specifically requests the functional purpose exemption for the point component of the BIC Children's Pen. The accessible portion of the nickel silver points assembly that BIC proposes to use in its BIC Children's Pen contains total lead of approximately 8720 ppm (point and point support subassembly). According to BIC, all of the other accessible components of the BIC Children's Pen contain total lead below 100 ppm.
BIC contends that removing or making excess lead inaccessible in manufacturing the BIC Children's Pen is neither practicable nor technologically feasible. BIC states that if BIC were to change the metal alloy to reduce the lead content to below 100 ppm, millions of dollars in high-speed manufacturing equipment would require retooling and use of cutting oil to produce the points, requiring significant resources and capital. In addition, BIC asserts that adjusting manufacturing processes in this way would result in lower point manufacturing productivity and a reduction in machine speeds and machine cycling.
BIC further states that the only metal alloy available for pen points that contain lead below 100 ppm is stainless steel. However, BIC does not produce stainless steel points in any of its factories. According to BIC, stainless steel points are more commonly used with water-based inks typically found in roller ball pens and gel ink pens. The BIC Children's Pen will not contain a water-based ink; rather, the pen will contain a solvent-based ink that is used in BIC's ballpoint pens.
BIC also contends that the BIC Children's Pen point is not likely to be placed in the mouth or ingested. According to BIC, the BIC Children's Pen is designed without a cap, clip, or pen body that can be opened. In addition, the point is securely adhered to the ink cartridge, and therefore, the point is not easily detachable, and the point is retractable. BIC states that the frequency of mouthing of objects by children who are intended to use the BIC Children's Pen is relatively low for the user age group (ages 5−12), and because the pen point is sharp, children will not mouth the pen point end of the product.
Finally, BIC asserts that granting an exception will have no measurable adverse effect on public health or safety, taking into account normal and foreseeable use and abuse because the potential exposure to the pen point would have no measurable increase in blood lead levels of a child. According to BIC, a child's fingers would not likely be in contact with the pen point during normal use conditions, and the point would be extremely difficult to grip. In addition, BIC states that a wipe test of the pen point shows that even in a worst case analysis (assuming purposeful dermal contact), the potential exposure to lead would be 0.31 µg/day, which is far less than the CPSC staff recommendation that 2.2 µg/day can be used in a determination of a "measurable increase" in blood lead levels of a child.
Through this notice, we invite written comments on the petition. Interested parties may view a copy of the petition under supporting and related materials identified by Docket No. CPSC-2013-0016, through http://www.regulations.gov. Interested parties also may obtain a copy of the petition by writing or calling the Office of the Secretary, Consumer Product Safety Commission, 4330 East West Highway, Room 820, Bethesda, MD 20184; email: firstname.lastname@example.com, telephone 301-504-7923.
Dated: April 25, 2013.
Todd A. Stevenson,
Secretary, Consumer Product Safety Commission.
[FR Doc. 2013-10093 Filed 4-29-13; 8:45 am]
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The Stem Cell Transplant Process
The Hematopoietic Stem Cell Transplant Program at Northwestern Medicine has become a leading stem cell transplant program, providing care and services for recipients and donors from Illinois, around the USA, and other locations around the world.
Stem cell transplantation, also called bone marrow transplantation, usually is used to treat cancers such as leukemia, lymphoma, multiple myeloma, and myelodysplastic syndromes. It also may be an option for those with aplastic anemia and myelofibrosis.
Once your doctor has referred you to the stem cell transplant program, a nurse coordinator will work with you to contact your insurance company and receive approval for the stem cell transplant. The actual stem cell transplant process begins with the collection of stem cells from either the patient or a healthy donor. Most stem cells are found in the bone marrow, the spongy tissue inside the large bones, and can also be found in the bloodstream with the help of certain medications.
The patient or donor donates stem cells via a machine called an apheresis machine. Stem cells are harvested from blood drawn through a catheter in the chest or neck. The blood flows through the line to the machine, which separates the stem cells from the rest of the blood. The remaining blood is returned to the donor through another line.
After the stem cells are collected, they are processed in the Mathews Center for Cellular Therapy. A lab technician evaluates the cells to make sure they are not infected and counts them to make sure there are enough for a transplant. Each bag contains several million stem cells.
Once stem cells are processed, they are preserved through a special freezing procedure. A thin, metal case contains the flattened bag of stem cells that will be placed in the freezer. Cooled by liquid nitrogen, the freezer keeps stem cells at 180 degrees Centigrade below zero.
The transplant happens through "reinfusion," a relatively simple and painless process wherein stem cells are infused into the patient. The stem cells are thawed in a room temperature water bath and then hung on an IV pole so they can be connected directly to the patient's IV, much like a blood transfusion.
After reinfusion, the patient enters the engraftment stage: stem cells migrate to the bone marrow and start producing new blood cells. Generally, engraftment takes one to three weeks before white blood cells are produced and 10 days to four weeks for red blood cells and platelets. Patients generally remain in the hospital for two to three weeks following their stem cell transplant to recover from any side effects.
Once discharged, stem cell transplant recipients are vulnerable to side effects and infection and will be seen in the HSCT clinic with their attending physician and a stem cell transplant APN.


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- Home
- No Mess Oil Filter Wrench - Large
No Mess Oil Filter Wrench - Large
Item #13951
- Capture the excess oil
- Protect your hands
- Eliminate the mess!
- See "Which Filter Wrench do I need?" Chart below
About No Mess Oil Filter Wrench - Large
Oil filters are designed to clean oil for proper operation and lubrication of the engine, and changing the oil every 3000-5000 miles (depending on make) is key to that engine's life. The oil and filter change is the #1 routine maintenance procedure performed by DIYers and professionals, and our No-Mess Filter Wrench device makes it so much easier and cleaner! Oil won't leak from the filter as the filter is unscrewed, and you'll avoid a potential "hot oil" safety issue. Patent-pending.
No-Mess Oil Filter Wrench -- Large
1. While the filter is on the vehicle, slide the tool on the filter. The inside of the tool is grooved so it forms a good grip on the filter. The flexible bellows will seal against the engine block.
2. Loosen the filter with a 3/8"-drive ratchet (insert in the square opening on the bottom of the tool). Reverse the ratchet direction to loosen the tool from the filter.
3. Remove. The excess oil is retained in the tool! No more oil on your hands, floor or undercarriage!
Always wear appropriate eye protection.
"Which Filter Wrench do I need?" Chart
Three sizes of Filter Wrenches are available. Click here to download a chart with a list of vehicles and their appropriate No-Mess Oil Filter Wrench device.


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Main Content
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Make checking out and paying up a little more exciting when you keep your cash and cards in this fabulous Texas A&M logo wallet! This polyester wallet has room for all of your necessities, and then some! It features an accordion-style billfold compartment with four slip pockets and a zippered pouch. The top features four card slips, an ID window and another billfold slip, while the exterior features another zippered pouch and an embroidered A&M wordmark! You'll love always having an extra dose of Aggies spirit when you keep your essentials in the classy wallet!
- Approximately 7.5" x 4" x 1.5" closed
- Approximately 7.5" x 7.5" open
- Exterior zippered compartment
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- Imported
- Interior zippered compartment with two billfold slips
- Made of polyester
- Officially licensed collegiate product
- Plastic ID insert
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- Two accordion-style billfold slip pockets
- Imported
- Brand: Bethel
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The 2011 NBA draft order will be decided tonight when the friendly ping pong balls drop for the worst 14 teams in the league in the annual NBA Draft Lottery.
Who goes first? Duke's Kyrie Irving or Arizona's Derrick Williams?
Remember, this isn't a particularly strong draft, so after those two, it's probably a free-for-all and trades are quite likely. Also, if Minnesota is able to convince point guard Ricky Rubio of Spain—its first-round pick in 2009 who decided to remain overseas to play ball—to play in the NBA, then it likely has no need for Irving.
In fact, the Timberwolves already have Jonny Flynn and Luke Ridnour at the point, though Irving is certainly and upgrade.
The NBA draft itself will be held on June 23 at the Prudential Center in Newark, N.J.
Tonight's draft lottery will be held in Secaucus, N.J., home of the NBA's television production studios.
Keep it with Bleacher Report for all the latest news, rumors and speculation surrounding tonight's Draft Lottery and the NBA.


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The Barfi! actor says she is hurt because of the things written about her in the media Priyanka Chopra has been in the news all through 2012 mostly because of her alleged link-up with Shahrukh Khan. But that's not the only thing PeeCee is concerned about.
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Ranveer Singh QUASHES all reports of Padmavati being delayed with these pictures!
Whoa! Disha Patani wants to marry Ranbir Kapoor and kill Tiger Shroff- watch EXCLUSIVE video!
Lisa Haydon announces her wedding with a HOT KISS - view pic!
After Shahid Kapoor, Sushmita Sen slapped with a BMC notice for breeding dengue mosquitoes!
Hrithik Roshan supports Karan Johar's Ae Dil Hai Mushkil!
Kajol trying VR gear for the first time is the most hilarious thing you will see today - watch video!
Shah Rukh Khan and Katrina Kaif to reunite before Aanand L Rai's film- details here!
Yeh Hai Mohabbatein 27th September 2016 Written Update, Full Episode: Nidhi caught red handed by Ishita and Raman!
Ranveer Singh has qualities similar to Shah Rukh and Salman Khan, suggests Rohit Shetty!
Sushant Singh Rajput's M.S. Dhoni: The Untold Story FORCES Sunny Leone's Beiimaan Love out of cinemas!
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Listen up Ranbir Kapoor, Salman Khan is #TeamShivaay!
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Katrina Kaif has NOT seen Ranbir Kapoor's Ae Dil Hai Mushkil trailer and here's PROOF!
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Shocking! Tannishtha Chatterjee walks out of Comedy Nights Bachao Tazaa citing racial abuse!
We have deets of Varun Dhawan's hush-hush date night - watch video!
Ranveer Singh, Tiger Shroff, Saif Ali Khan - who looked the HOTTEST at the GQ awards 2016? View HQ pics
Salman Khan SAVES Karan Johar from the wrath of Raj Thackeray's MNS - here's how!
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Never miss any important news!


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HP Officejet Pro 8600 Premium Wireless e-All-in-One Inkjet Printer 911n, 20 ppm, Up to 4800 x 1200 pdi (Color), 500-sheet Paper Capacity, & extra set of Color Ink (Cyan, Yellow, Magenta) - CN577A#B1HItem#: H24-30317 | Model#: CN577A#B1H
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HP Officejet Pro 8600 Premium WiFi e-All-in-One Product Details
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The clock is ticking!
There's less than a month to go until the Runner's World Half Marathon.
So far, 6,000 runners are registered, and they're coming from all over the world.
Bart Yasso, Chief Running Officer from Runner's World, stopped by 69 News at Sunrise to tell us how preparations for the 3-day festival are coming along, and he offered some last-minute tips for runners competing in the race.


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on February 5, 2013 - 1:50 AM
, updated February 5, 2013 at 6:54 AM
Alexandra Fuller will answer your most pressing questions right away. ¶ Yes, her mother still lives in Africa. ¶ And yes, that unique mother, now a grandmother of nine, is as glamorous and feisty and strong-willed as ever. ¶ Fuller also offers that her mother has just come through a painful stomach operation – with minimal anesthetic – in Lusaka, the capital city of Zambia and the nearest place of any size to her parents' rural African fish and banana farm.
"There's Granny," said Fuller, laughing ruefully at the thought. "Awake through abdomen surgery, and joking about it!"
"Cocktail Hour Under the Tree of Forgetfulness," Fuller's memoir of life in Africa with her parents, is the February selection of The Buffalo News Book Club. She shared glimpses of her life story – and that of her unforgettable family – on the phone from her home in Wyoming.
Fuller was born in England in 1969 but lived most of her life in Africa. "Cocktail Hour" is her second memoir. Her first memoir, "Don't Let's Go to the Dogs Tonight," was a prize-winning best-seller after its release in 2001.
Now, readers who enjoy Fuller's writing also will have a chance to hear her speak in person, when she appears in early March as part of Just Buffalo's Babel literary series. Fuller's talk will take place at 8 p.m. March 7 in Kleinhans Music Hall.
Fuller, whose voice carries a British accent mellowed by her time in Africa and the American West, admitted that she is not entirely sure whether this will be her first time speaking in Buffalo – although she thinks it is.
"Isn't this awful?" asked Fuller. "I say that because, over a decade, things get physically blurry; you go places you don't think you've been.
"I've been other places in upstate New York, but not Buffalo. I'm very excited."
On one of her previous trips through the upstate region, Fuller said, she got a chance to see Niagara Falls, from the Canadian side.
Did it remind her of Africa's famous Victoria Falls, reputedly one of the most beautiful waterfalls in the world?
Fuller pauses, trying to remember.
"It was a thousand years ago," the author said, at last, of her visit to the African waterfall. "Victoria Falls was still really, really wild back then. I gather Victoria Falls is very much more developed now.
"That's the unfortunate way humans are – we can't leave natural things alone, without needing to put a T-shirt shop in front of it."
Fuller's writing, for those who have not yet experienced it, comes as a bracing, sobering, thought-provoking jolt of energy.
In "Cocktail Hour," she relates with bluntness and humor the story of her unusual family: her strong and proud Scottish-born mother; her well-born English father, son of a commodore in the British Navy; her siblings, four of them in total, only one of whom lived to reach adulthood – her sister Vanessa, who today lives in Africa with her husband and family of six children.
Fuller's parents, Nicola and Tim, met in Kenya, and began their marriage and family in central Africa. ("Nicola Fuller of Central Africa!" became the signature introduction that Fuller's mother would use over the years with one and all.)
The way her parents saw it, Fuller explains in her memoirs, they were "well-bred" Scottish-English people trying to organize and make successful farming operations in an African countryside that was still wild and untamed, unpredictable and full of treacherous, shifting beauty. Fuller makes no bones about what she calls her mother's sometimes "racist" tendencies, in "Don't Let's Go to the Dogs Tonight."
After dispiriting setbacks, including the loss of a child, the couple tried moving to England – which is where Fuller was born, in 1969.
But Nicola and her husband soon decided that the only place they could truly live the way they wanted was Africa – despite its starkness, its harshness, its brutality.
The beauty of the continent, and its sense of adventure and possibility, made up for those things, Fuller writes in "Cocktail Hour."
"The worst thing you can be called in the part of Africa I come from," said Fuller, "is boring."
The family moved to Rhodesia (now Zimbabwe), then Malawi and other places, before settling in Zambia.
Along the way, the Fullers lost three children to early death (one to drowning in a shallow pool, rendered simply and terrifyingly in both of Fuller's memoirs); they lost possessions, money, animals they loved – particularly dogs and horses, the peculiar passion of Nicola Fuller and her clan.
"People want happy stories. Happy ever after," said Fuller, of her description of these events in her books. "But there's hardly ever resolution in life. There's enormous amounts of loose ends."
With each move and each new vista in the African wilderness, the Fullers were seeking land – and less tangible things, their daughter said. Things like liberty, and solitude, and a farm they could call their own.
"I think it's always been a bit of a love triangle," said Fuller. "My mother's always been in love with land, and my father's always been in love with her."
In "Don't Let's Go to the Dogs Tonight," Fuller told what she called the story of her "African childhood."
The story in "Cocktail Hour" reaches back further than that – in part because her mother was upset about the focus of the first memoir, Fuller said.
"It's funny, you write the book and then it's only a few years later that you realize what it's about," mused Fuller, of her first memoir. "I wrote this memoir a decade ago, and ... one of my mother's objections to that book was, 'You never asked me about who I am!' "
" 'Don't Let's Go to the Dogs Tonight' was a memoir, [but] it wasn't about my mother," Fuller said. "In it, she's just sort of a terrible mother. But, as a woman in your 40s, [now it seems like] she's a wonderful mother. By your 40s, you've lost that arrogance of youth. You've made mistakes, you've hurt people.
"This is really a story about that."
Fuller, who was married for 20 years to Charlie, an American river guide she met in Africa, has three children of her own. She said she gets back to Africa to visit her parents in Zambia several times a year. She and Charlie are now divorced, Fuller said.
Fuller said she loves Africa deeply – and sometimes even considers moving back there, to live in the place that still feels like home in many ways.
"A piece of me is still African," she said.
But the United States feels like home, too, Fuller said. And in this country, which she also loves, she realizes the value of certain rights and privileges that she said people who live all their lives here might not fully appreciate.
"That place gave me my voice," Fuller said of Africa. "But this country gave me my ability to use my voice. People don't really understand that, I don't think."
Later, she adds this:
"I feel at home here because it's the place where I live. I've made friends here, I love the mountains here. There's a lot about this country that I value.
"I think about it every day."
Fuller has no regrets about writing about her mother in such unvarnished ways: about what Fuller calls Nicola's drunken episodes, her mental and emotional breakdowns, her tragic loss of children, her tough mothering style.
"She's not a monster," said Fuller of her mother. "We just have this very sanitized version of what a mother should be like."
Nicola was "angry" after the memoirs came out, her daughter said.
But, she said, her kind of family – and her kind of homeland – is one where stories get told, and reacted to, and then life goes on.
"You have to really love someone to write about them honestly," Fuller said, "and to know that they will forgive you."
And, Fuller said, more often than not, readers end up telling her that they see reflections of their own families – their own mothers – in Nicola Fuller.
"People often say, 'I had a mother like this, or an aunt, or a grandmother,' " said Fuller. "So we aren't as far apart as we think. We really transcend our differences.
"Everyone's got a mother. She may not be like my mother. But we do share that."
Alexandra Fuller's publishers have supplied The Buffalo News Book Club with multiple copies of her latest memoir, "Cocktail Hour Under the Tree of Forgetfulness," to give away to interested Book Club readers.
To be considered for a copy of the book, drop a line to the Book Club staff. Tell us why you'd like to receive a copy. We'll pick a few names to get copies by mail.
To reach us, write via regular mail to The Buffalo News, Book Club/Features Dept., P.O. Box 100, Buffalo, NY 14240 or email us at firstname.lastname@example.com.
The Babel Series
Alexandra Fuller will discuss her work as part of the Just Buffalo Babel series at 8 p.m. March 7 in Kleinhans Music Hall, 3 Symphony Circle.
A question-and-answer session and book-signing will follow the program.
Tickets are $35; $25 with a Buffalo & Erie County library card; $10 for students; call 832-5400 or visit www.justbuffalo.org.
email: firstname.lastname@example.com


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Neither Scott Brown nor Elizabeth Warren had much to say during their campaign about Warren's expertise on bankruptcy and financial regulation.� Writing for The Daily Beast, Daniel Gross makes her sound like an impact player:
At no time in recent history has there been a senator who knows so much about Wall Street�and is so little beholden to it.
Gross says the assumption is she'll be named to the Senate Banking Committee, where she'll be able to oversee the implementation of Dodd-Frank and protect her Consumer Finance Protection Bureau from efforts to undermine it.� But while Brown caricatured Warren as a party-line Democratic hack, her record suggests otherwise:
Neil Barofsky, the former inspector general of TARP, expects Warren to cause bipartisan trouble in Washington. �She will bring a lot of headaches to the Democratic leadership�or at least that�s what I hope she does,� says Barofsky, who worked with Warren on TARP oversight.Several Democrats, including Treasury Secretary Tim Geithner and Sen. Chris Dodd, didn�t support her efforts to run CFPB. If the past is any guide, protecting consumers from the predations of financial firms will likely put her in direct conflict with her party�s leadership. And Warren isn�t a go-along-to-get-along type. Barofsky recalls with evident glee that Warren �just filleted Geithner� at a June 2010 public TARP oversight hearing. �There was no good reason for her to do so as someone who was campaigning for an administration position,� notes Barofsky, now a senior fellow at the New York University Law School and author of the memoir Bailout. �That makes her potentially very powerful and potentially very dangerous.�


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Here we provide a platform where we share information and invite dialogue about Keystone Issues - those processes central to the survival of our planet, and humanity's continued existence on it.
WildiZe's Keystone Issues includes topics on species, ecosystems and those natural and man-made processes that have disproportionately large effects on our planet's biological communities for which we depend upon to sustain us.
For more information on this critical topic see our suggested reading list and posts with linked articles.
Filed Under: Keystone Issues
Tanzania police seize poached elephant tusks
(Reuters) - Tanzanian authorities have seized more than 1,000 elephant tusks hidden in sacks of dried fish at Zanzibar port which were destined for Malaysia, officials said on Wednesday.
Like other countries across sub-Saharan Africa rich with wildlife, Tanzania has suffered from increased poaching in recent years as criminals kill elephants and rhinos for their tusks which are used for ornaments and in some medicines.
A total of 1,041 elephant tusks were stashed in a container with 114 sacks of dried sardines earmarked for export. The tusks nabbed in Zanzibar likely originated from mainland Tanzania.
Two suspects have been arrested and are being [read more...]
Filed Under: Keystone Issues
1071 Elephant Tusks Siezed on Zanzibar Island
August 25, 2011 - Tanzanian authorities seized 1,041 elephant tusks on the island of Zanzibar yesterday - the largest ivory haul in a year of devastating loss.The record-setting seizure comes as 27 wildlife law enforcement officials from 11 Southern African countries gather in Gaborone, Botswana this week to undergo a joint IFAW and INTERPOL training session on the prevention of illegal trade in wildlife. Click here: http://www.ifaw.org/ifaw_canada_english/media_center/press_releases/8_25_2011_71715.php[read more...]
Filed Under: Keystone Issues
Kenya, Again- Takes a stand against the selling of ivory
There was an ivory burn in Kenya in the 1970's, to speak out for the ban of the sale of ivory toward the protection of elephants. That burn took place in Nairobi National Park, overseen by then president Daniel Arap Moi. Here again, in July, another burn took place Here is a link to the July burn in Tsavo National Park: http://youtu.be/AElxLdGWF2U under President Kibaki and Kenya Wildlife Service. The rise in poaching across E.Africa and elsewhere across Africa where there is wildlife and elephants, is reaching levels of the 70s, 80, along with severe droughts. China and Asia [read more...]
Filed Under: Keystone Issues
Best response to manage recurring drought
Here is an excellent article, provided by Evanson Kariuki our Kenya Field Coordinator, that outlines issues to date on managing response to recurring drought. Kenya is facing severe drought, worse than 2009, worse than 2004. In 2010 WildiZe participated in the 5yr Area Disaster Management Plan workshop held in Kalacha, south of Marsabit, and helped to spread the information throughout the Kalacha community and Loiyangalani, further south.
This year it seems billions are being funneled through from foreign aid, and individuals alike, yet, what is happening? There is still severe drought and inadequate response on the ground, [read more...]
Filed Under: Keystone Issues
Agony and Ivory
In Vanity Fair, Alex Shoumatoff's article, Agony and Ivory, finally someone is saying it out loud: The role Asia and specifically the Chinese have in the upsurge in elephant poaching and the ivory trade. Read this article a, and be sure to pass it on. The only way elephant poaching for ivory will reduce is when everyone knows and decides to take a step to stop it- whether through donating time, money or talking to their friends and communities. Read it here: http://www.vanityfair.com/culture/features/2011/08/elephant [read more...]
Filed Under: Keystone Issues
KWS catches longtime poacher-Meru-Kora-Garissa
KWS has been going through a lot of excellent changes, and they're better than ever. Still some way to go toward stopping ever prevalent poaching and bushmeat in areas that are widespread and remote. This catch is well on the way toward halthing both: http://youtu.be/2KYRitXLxS8 [read more...]
Filed Under: Keystone Issues
Asbestos Trade hurting African, Southeast Asian environment
As we all known, Africa is the home to numerous wildlife and conservation efforts. Even with massive efforts to put an end to the destruction of wildlife, there are some surprising obstacles getting in the way of true conservation. The spread of environmental toxins such as asbestos fibers around Africa and Southeast Asia is a major hurdle in the fight for a safe land for wildlife and nature. This is not a process that's been natural either. Asbestos mines stopped in Africa around 2002, yet other countries continue to export the material into developing areas.
Canada is [read more...]
Filed Under: Keystone Issues
Amboseli lions poisoned and mutilated in Tanzania
"Two lions have been found dead and their bodies mutilated after being deliberately poisoned in Tanzania. First, a female lion was targetted after it had killed a cow, and once the lion was dead, its skin, teeth and claws were removed - all items that would fetch a lot of money on the black market." You can read the full article here.
Unfortunately, not all poaching is for medicinal horns and folk remedies. Lion numbers are being devestated through Africa and this type of report helps to capture some of the primary issues being [read more...]
Filed Under: Keystone Issues
Another Global Warming Report
Global Warming continues to spread its insidious tentacles throughout the animal world. The New York Times, today, ran another report showing how animal populations are continuing to be stressed by climactic alterations. These reports are strenghtening the scientific knowledge showing long-term negative trends, lending credence to many beliefs that we are on the precipice of another massive extinction crisis.
Solutions continue to allude our national leaders, and unfortunately, the time for action is now (well, really yesterday and the years before). Fortunately, there are glimmers of hope for the needed changes across our society, but can we [read more...]
Filed Under: Keystone Issues
Excellent Article on Kenya Lions by Laurence Frank
This is a great summary on the current status of Lions, primarily in Kenya. This is not only valuable in laying out the problems impacting the Lions, but lays out some great solutions to help reduce Human-Lion conflicts.[read more...]
Filed Under: Keystone Issues
WildiZe Sub-Saharan Lion Conservation Project
In order to combat long-term Lion population reductions, the Wildize Foundation has begun a Sub-Saharan Lion Conservation Project. This effort is being coordinated through several on-the-ground projects we are currently funding, along with new projects proposed and further envisioned. This pan-African project is attempting to address the numerous underlying causes for the Lion's decline and as much as possible includes local community involvement so as to reduce the conflicts leading to their demise. With numerous American and European funded projects already being attempted to reduce this decline, we feel [read more...]
Filed Under: Keystone Issues
Biodiversity Loss Linked to Spread of Diseases
We in the conservation field frequently refer to the ol' "the cure for cancer might be in that forest" argument for why biodiversity is important. Now there is a group of scientists that have taken it a step farther and shown that there is a link between biodiversity loss and the spread of diseases. The full report will be released tomorrow, but here is an article about it from Science Daily: http://www.sciencedaily.com/releases/2009/12/091203132157.htm [read more...]
Filed Under: Keystone Issues
WildiZe in the News!
Is Africa our 21st Century Climate Canary?
Even though it seems far away from the U.S., we make the point that the ongoing destruction of Kenya's Mau Forest Complex and our ever increasing human footprint is coming home to roost, and the consequences for us all.[read more...]
Filed Under: Keystone Issues
US Climate Bill: 7 things you should know
We're long past due for a new Climate Bill in the US, and hopefully in Copenhagen our global leaders will hash out a new climate treaty and the US will hop onto this speeding train. There are no single steps toward reducing our impacts on climate- it's going to take multi-layered top-down and bottom up leadership, regulation, community and individual action address these critical issues. Especially as 3 billion people around the globe reach toward a better purchase on the economic ladder, and as China and India increase their impacts in the global economy, while developing countries seek ways to [read more...]
Filed Under: Keystone Issues
China - The Superpower in Africa
You can really tell that the Cold War is over. We almost never hear about the influence China is beginning to have in Africa. If Russia had this much reach during the Reagan era, we might have already experienced World War III.
Since the 1960's, the West's relationship to Africa has been primarily built around foreign aid. Billions of dollars have been given in food aid, medical supplies and other direct assistance. It would be difficult to make the claim that these efforts have been wildly successful. Most of the problems that the money has been [read more...]
Filed Under: Keystone Issues
The Importance of Rain
We have forgotten the importance of rain. Just for fun one day, take the 5-gallon jug out of the water cooler at your office and see how far you can carry it on your head. Oh, and borrow a two-year-old to carry on your back at the same time. See how you feel after the first couple of miles, and then think about how lucky we are!
For those of us living in the industrialized world, we take it for granted that when [read more...]
Filed Under: Keystone Issues
Too Many Lions...
Ironic, isn't it? Just as scientists are predicting the complete demise of the lion population in Kenya within the next 10 - 20 years, South Africa has 3,000 "extra" lions that it just doesn't know what to do with.
The circumstances, of course, are quite different in these two places. In Kenya, the lions are disappearing primarily because local people are killing them. These are people living on an incredibly thin margin for survival in the best of times, and devastating droughts in recent years have pushed them even [read more...]
Filed Under: Keystone Issues
Are we on the brink of saving rainforests?
Until now saving rainforests seemed like an impossible mission. But the world is now warming to the idea that a proposed solution to help address climate change could offer a new way to unlock the value of forest without cutting it down.[read more...]
Filed Under: Keystone Issues
Kenya Wildlife down by 40%
Common species in decline in National Parks
http://www.wildlifeextra.com/go/news/kenya-wildlife-decline.html[read more...]
Filed Under: Keystone Issues
Map of elephant DNA reveals trail of ivory smugglers
Scientists have used a revolutionary genetic technique to pinpoint the area of Africa where smugglers are slaughtering elephants to feed the worldwide illegal ivory trade.
http://www.guardian.co.uk/science/2009/jun/28/elephant-dna-illegal-ivory-trade[read more...]
Filed Under: Keystone Issues
Humanity at risk due to unsustainable development
The average human ecological footprint of 21.9 hectares per person is way beyond the Earth's biological capacity of just 15.7 hectares per person
http://www.thaindian.com/newsportal/sci-tech/humanity-at-risk-on-earth-due-to-unsustainable-development_1002620.html[read more...]
Filed Under: Keystone Issues
Elephants as Keystone Species
Scientists undersyand that living communities of plants and animals depend keenly on one another for survival. http://www.fieldtripearth.org/article.xml?id=754 [read more...]
Filed Under: Keystone Issues
Keystone Conservation
The keystone at the top of an arch holds all the stones in place. Without it, the arch collapses. Healthy ecosystems needs keystones—like wolves and whitebark pines—to function. Keystone species are the architects of biodiversity. http://keystoneconservation.typepad.com/keystone_conservation/keystone-species.html [read more...]
Filed Under: Keystone Issues
What is a Keystone Species?
A keystone species is a species that plays a critical role in maintaining the structure of an ecological community and whose impact on the community is greater than would be expected based on its relative abundance or total biomass. http://animals.about.com/od/animalswildlife101/f/keystonespecies.htm [read more...]
Filed Under: Keystone Issues
Lions at Kenyan park being wiped out
Lions in Kenya's Amboseli National Park face extinction within a few years unless action is taken to help them. (June 12, 2008)[read more...]


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CHP: Napa woman arrested for 6th DUI
45-year-old also violates probation, authorities say
A California Highway Patrol officer has arrested a Napa woman on suspicion of driving under the influence for the sixth time.
The Santa Rosa Press Democrat reports that 45-year-old Ixchel Susan Rollins was pulled over as she drove a BMW on Highway 101 in Petaluma at about 2:15pm Friday.
CHP Officer Marcus Hawkins says Rollins failed field sobriety tests and was taken into custody on suspicion of felony DUI as well as violating probation and driving on a suspended license.
Hawkins says Rollins had previous convictions for DUI in 1991, 2000, 2006 and 2007. CHP officials say she was booked into Sonoma County Jail in lieu of $30,000 bail.
Rollins is due in court Wednesday but it was not immediately clear whether she had retained an attorney.
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