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Introduction to the Process of Technological Innovation
This course is an introduction to the nature of technology and the process
of technological innovation. It examines how technological change is associated
with the emergence of new industries, changes in the structure of existing
industries, and changes in firms and other organizations active in the
commercialization of technology. To illustrate these themes the course
outlines the parallel histories of the personal computer industry, the
computer networking industry, and organizations that have played a key
role in the evolution of those industries. It examines the impact of technological
convergence and turbulence on competition and cooperation between firms,
and provides a framework for linking technology strategy with corporate
Technical Standards and Competition in High Technology Industries
This course explores the nature of technological innovation by examining
one of the distinctive features of competition in technology-based industries,
the formation and evolution of technical standards. It will explore how
developing and controlling technical standards may be used by firms to
manipulate competitive forces, and how failure to properly address competition
around standards may undermine a firm's position in the market. The course
will also examine the variety of institutions and systems that have emerged
for establishing and forcing technical standards, both within the United
States and internationally. Economic, political and business forces affecting
the evolution of standards will be studied.
Macroeconomic Perspectives On Technological Change
This course analyzes the effect of technological change in a macroeconomic
model. Specifically, this course develops a framework of technology as
the embodiment of culture and history, requiring the co-evolution of technology
and institutions as a model for economic growth. The course concentrates
on the generation of new technologies, the effect of new technologies
on the macro economy, the diffusion and adaptation of technology, and
the cyclical nature of technological change in growth. Prerequisites:
Microeconomic Perspectives on Technology and the Economy
This course analyzes the decision processes of firms and industries in
incorporating technological change. Specifically, the course analyzes
the firm's production inputs decisions, modeling technology as an input
and an output. The course develops production and output models, and models
each of these in different industrial structures (perfect competition,
oligopoly, and monopoly). The course also develops pricing models in the
face of demand conditions. Prerequisites: MBATM 610.
The Development of New Technology Products
This course examines: the key stages and tasks involved in the development
of new technological products; managing the interfaces between key functional
groups in the product development process; the role of the project manager;
the link between product strategy, business strategy and overall marketing
strategy; product design and architecture; product platform strategy;
managing new product realization programs; and managing the technology
adoption lifecycle. Prerequisite: MBATM 611.
Marketing of Technology
This course addresses the challenges of bringing products based on new
technology to market. It covers the basic principles of pricing, promoting,
and distributing new products through evolving channels. Special topics
include: understanding unarticulated user needs, demand forecasting in
technology markets, marketing technologies to intermediate industrial
customers and other technology firms, and the role of industrial networks
in technology marketing. Prerequisite: MBATM 611.
Technology and Organizational Behavior
This course provides a framework for understanding the crucial importance
of leadership for success in technological organizations. It also examines
the variety of ways in which human behavior within organizations and groups
may affect technology commercialization processes. The framework will
be explored through role-plays, simulations, case analyses, and exercises
designed to help students apply behavioral concepts in practical technological
settings. MBATM 610.
Human Resources and New Technology
The course focuses on the human-resource systems and processes that technology
firms need in order to achieve productivity, satisfaction and development
among employees. Special attention is placed on recruitment, acculturation,
training and retention strategies for highly skilled knowledge-workers
sought after by successful technology organizations. Prerequisite: MBATM
Fundamentals of Financing Technology Ventures
Technology ventures often differ from the conventional enterprises in
a number of ways, including their degree of risk, their lack of positive
cash flow, their unconventional business models, their emphasis an intangible
assets, or the lack of business-experience of their founders. This course
will review the variety of solutions technology entrepreneurs have developed
to finance their operations in the face of these constraints. Topics include:
angel investing, venture capital, specialized private equity funding,
public equity, personal or family investing, government grants, strategic
partnerships, sweat-equity capital, and revenue based financing. Strategies
for mixing sources of capital throughout the stages of development of
an enterprise will be studied. Prerequisites: MBATM 614.
Legal and Strategic Issues in Financing Technology Ventures
As firms progress through the stages of financing the commercialization
of new technology, a plethora of legal and procedural requirements or
obstacles need to be traversed. These include Securities and Exchange
Commission regulations, due-diligence procedures, state and federal business-law
requirements, complex documentation required for various financing events,
and tactical maneuvers associated with key stakeholders connected to each
financing stage. This course will review legal, administrative and strategic
issues associated with entrepreneurial technology financing. Prerequisite:
Intellectual Property Law
The sophisticated management of intellectual property is a cardinal capability
of successful high technology firms. This capability draws upon specialized
knowledge from a variety of fields, including law, science, engineering,
business methods, R&D management, corporate strategy and public administration.
This course introduces the field of intellectual property management by
focusing on one dimension of the field, intellectual property law. Lectures
cover black-letter law and current legal practice in a variety of fields
of intellectual property, including: patents (process patents, product
patents, design patents, etc), trade-secrets, copyright, trade-marks (and
other marks), confidential business information, material exchange agreements,
and associated legal concepts. Comparisons are made between intellectual
property law, and intellectual property administrative regimes, in the
United States and other countries. Prerequisite: MBATM 610.
Intellectual Property Strategy
This course examines how the management and protection of intellectual
assets may be integrated within the management of a firm, to fulfill corporate
goals and build sustainable competitive advantage. It introduces the concept
of an intellectual property audit, and discusses how firms may design
intellectual property portfolios linked deliberately to technology strategy,
research strategy, market strategy, and overall corporate strategy. Consideration
is given to methods for harvesting surplus value through exploiting underutilized
intellectual property, and to employing intellectual property as a tool
for managing relationships with competitors and partners in business.
The practical and ethical challenges of managing intellectual property
across international boundaries will be given special attention. Prerequisite:
Licensing Strategy
In addition to the protection of intellectual assets, the successful
management of intellectual property also involves prowess in trading intellectual
assets. This course examines this topic by reviewing the basic legal and
managerial dimensions of licensing intellectual property. Topics covered
include: introduction to the legal framework for licensing in the United
States and internationally; procedures for licensing out intellectual
property; procedures for licensing in intellectual property; cross-licensing,
cooperation and competition; linking licensing strategy to intellectual
property protection; and, linking licensing strategy to overall corporate
strategy. Prerequisite: MBATM 621.
Technology Commercialization, Research Institutions, and Government
The technical and scientific knowledge exploited by technology companies
frequently originates outside firms, in university laboratories, research
institutes, government agencies and other public institutions. Technology
commercialization often requires transferring technology from such sources;
the successful management of that process, in turn, requires an understanding
of the culture, structure, politics and modes-of-operation of this group
of organizations. In addition, government regulations, technology policies
(federal, state and local), public sector purchasing policies, and various
economic development programs, may form an important part of the business
environment surrounding a technology venture. This course reviews the
features of the "non-commercial" domains of the technology sector
and examines factors that managers of technology enterprises will need
to appreciate when interacting with the organizations from those domains.
Prerequisite: MBATM 622.
International Dimensions of Technology Management
Because both the sources of technical expertise and the markets for new
technology are normally international, most successful technology enterprises
engage in international business activity throughout the stages of commercialization
of their processes and products. In contrast to conventional wisdom it
is not uncommon for technology start-ups to launch international activities
immediately rather than during mature phases of the firm life cycle. This
course will examine the international behavior of technology firms and
will also review legal, political, economic, and cultural issues involved
in cross-border technology-related business. Prerequisite: MBATM 623.
Organizations, Technology, and Society
The process of technology commercialization may have an impact not only
on those stakeholders with direct business interests in an enterprise,
but also on society at large, people in the core organization, or special
interest groups. In addition, social and organizational factors may have
impacts, both positive and negative, on the technology commercialization
process. This course will consider ethical issues associated with technology
commercialization, in social and organizational contexts. Prerequisite:
Principles of Managing Technology Projects
Competitive pressures in technology industries require that firms be
capable of delivering technology projects on time, under budget, and within
specification. This course introduces management tools for insuring successful
delivery of projects. The course covers some specific tools from a variety
of sources that have been used widely to assure success of strategically
important projects. Students also create Timebox plans appropriate for
defined business objectives, and will learn how to facilitate meetings
with precise purposes visible to participants and to stakeholders. Prerequisite:
Implementing Technology Projects
Many technology firms have found that successful technology commercialization
requires collaborative development efforts originating at the earliest
stages of the commercialization process. The application of facilitated
project management techniques enables joint and rapid delivery in fast
paced technology environments. This course utilizes technology project
management tools from idea stage to implementation: Business & Feasibility
study, Outline Prototyping Plan, Structural Architecture Development,
Functional Modeling, Scheduling and Implementation. Prerequisite: MBATM
Design and Evolution of Technology Commercialization Strategy
This course is the first in a pair of courses that together provide the
capstone experience in the technology commercialization program. Both
courses operate from the vantage point of the firm; and they discuss what
general managers need to know about integrating technology within the
firm's strategy and about assessing a firm's capacity for innovation.
This course studies the substance of technology strategy and the key external
and internal forces that determine its evolution. Topics include: entrepreneurial
strategy in technology; developing and maintaining distinctive technological
capabilities; management criteria for effective innovation; patterns of
industrial innovation; profiting from technological innovation; dealing
with technological competition; intra-organizational ecology of technological
strategy-making; architectural innovation; and strategic intent in technology
enterprises. Heavy use is made of case studies. Prerequisite: MBATM 623.
Enactment of Technology Commercialization Strategy
This course, the second in a pair of capstone courses in the technology
commercialization program, deals with key issues in implementing a technology
strategy: internal and external technology sourcing; managing corporate
innovation; managing corporate R&D; strategic alliances and internal
corporate venturing; and technology acquisitions. This course also places
special emphasis on the challenges of managing technological innovation
in established or mature firms. These challenges include: exploiting opportunities
associated with the core business; exploiting new opportunities that emerge
spontaneously; balancing the emphasis between the different types of opportunities;
and stimulating strategic technological renewal. Heavy use is made of
case studies. Prerequisite: MBATM 623.


text: Billy Joel and Christie Brinkley may be divorced, but she'll always be his 'Uptown Girl.' Brinkley, 60, sat in the front row last Thursday at Joel's New York's Madison Square Garden concert -- and she was spotted dancing the night away in a video uploaded on YouTube by a fellow concertgoer. (Photo credit: Getty)

subset: commoncrawl


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Darksiders for Xbox 360On: Xbox 360, PS3, PC
Deceived by the forces of evil into prematurely bringing about the end of the world, War, the first Horseman of the Apocalypse, stands accused of breaking the sacred law by inciting a war between Heaven and Hell.
Stuck on Darksiders? We've got you covered!
Don't panic! Our cheats will see you through.
Nordic in talks with ex-Vigil devs about Darksiders 3 collaboration
But still no concrete plans for second sequel, publisher suggests.
Nordic Games the only bidder to meet THQ's reserve for Darksiders
Vigil co-founder Ryan Stefanelli offers advice on taking the franchise forward.
Crytek USA is 'looking to buy Darksiders'
Ex-Vigil Games dev to bid on Darksiders IP when series goes to auction.
THQ to auction off remaining IP, including Darksiders, Red Faction and Destroy all Humans
Expects process to be completed by mid-May.
The Week in Review: THQ's gone, but Nintendo is back in the game edition
The Week In Review is a weekend feature which takes a fine-toothed comb over the week that was, hoping to point your eyes in the direction of news, features, videos and reviews which I deem to be worthy of your precious time.
Vigil's new game is a jaw-dropper, says THQ president Jason Rubin
The fact nobody bid for the team is a 'travesty' says Rubin.
View AllScreenshots
Demo Launch Trailer
Demo Launch Trailer
Launch Trailer
Launch Trailer
Accolades Trailer
Accolades Trailer
Reborn Trailer
Reborn Trailer
Hellbook Four: Ruin
Hellbook Four: Ruin
Hellbook Three: The Hordes of Hell
Hellbook Three: The Hordes of Hell
Hellbook Two: War's Arsenal
Hellbook Two: War's Arsenal
Hellbook One: The Horseman's Road
Hellbook One: The Horseman's Road
Art Feature
Art Feature


text:
Predascent for Deer
This item is currently not available.
Additional Information
Predascent Offers Easy, Clean, Long-Lasting Protection Against Deer
- Protect your garden from voracious deer
- Safe and easy to use
- 20 capsules per box make an 80-foot perimeter, or cover 750 square feet
- Protection lasts 4 to 5 weeks
- Rain or watering actually increases effectiveness
Predascent banishes one of your most frustrating garden pests: deer. Just moisten these gel capsules, and spread them 3-1/2 feet apart to create a perimeter around your garden. Odorless to humans, deer will smell predator urine and run for their lives.
Product Details
- Agricultural polymer with predator urine
- 20 capsules per box
- Makes an 80' perimeter barrier or covers 750 sq. ft.
- Effective for 4-5 weeks
There are no special shipping restrictions or charges associated with this item. For detailed information about our delivery methods and charges, click here.
We're proud of the fact that this item is shipped to you directly from our warehouse in Vermont, by one of our 250 employee-owners. In-stock items are packed with care and shipped within the next business day to ensure prompt delivery to your home and garden!


text:
Trojan baseball crushes Anderson (S.C.); softball team splits with Francis Marion (S.C.)
By MOC Sports Information
Published in Sports on February 22, 2010 1:46 PM
Please log in to see full story.
Other Local Sports
- Defending champs survive
- Prep basketball boxes
- Nowak shuts down Wingate in 7th
- Trojans' Moore, Easley, Leeper, Hudson receive notoriety
- No. Guilford downs Eastern Wayne girls
- Chargers rally past Cresset
- ECU's Wooten, Wright each slug homer
- Cougars halt Rocky Mount Prep
- C.B. Aycock dominates Nash Central
- Prep basketball boxscores


text:
Timeless music: Enjoyed by generations
If I asked my grandmother who Lady Gaga is, she'd have no idea, but if I asked about 'The Beatles, she'd likely sing any number of tunes, as would my parents, as would I, and as would my kids.
Some musicians are timeless. From classical masters to the more contemporary, some music simply spans the generations.
Today is Sir Paul McCartney's 70th birthday. Born in Liverpool on June 18, 1942, his parents, Mary and Jim, couldn't know that their son would become one of the most influential musicians in the world, and part of a band that would enjoy global success.
What musicians or bands are enjoyed by the generations in your family? Do you share a favorite singer - or a timeless tune - with your grandparents or grandchildren? Share your answers in the comments section below, on Facebook, Twitter or Google+.
Happy birthday, Sir Paul!
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text:
Top Definition
A from the nadsat language meaning blood.
After he was struck in the face repeatedly the red red kroovy began to flow.
di Phineas 16 ottobre 2004
Trending Now
Can you define these popular missing words?
A website which will soon bring music to your ears.
I just listened to 3 different countries music on kroovy!
di thedaygoesby 10 luglio 2008


text:
[western day at school]
I've been reminding my boys
d a i l y:
A good friend (and brother) brings attention to each others' strengths, and prays in secret for their weaknesses.
A good friend (and brother) brings attention to each others' strengths, and prays in secret for their weaknesses.
We have similar photos up today. :)
What a beautiful reminder for your boys. My youngest two need this reminder also, of course though, don't we all?
Thank you.
This is a good reminder that is perfect for me today. Thank you!ReplyDelete
So cute! What a great reminder for you boys. I pray that when my monkey man turns that age I will be able to be that encouraging.ReplyDelete
Cute picture and great quote.ReplyDelete
I love, love, love that.
I love the picture, adore that picture ;-)
and that is a perfect reminder. I need to chat that daily to my children. Maybe I can also whisper it repeatedly in their ears while they sleep?
A wonderful reminder I will be SURE to share with my kids (read: OLDEST SON), too.
BTW, we had a cowboy day, too. Except yours is wayyyy better. Mine was a pitiful, piddly excuse for a cowboy costume. LOL
This put a smile on my face. Noah couldn't be any cuter! Great quote too!ReplyDelete
What a great thing to teach children! Hopefully I'll be remembering that one! ;) I love the pic too! He looks so rugged and handsome...ReplyDelete
I love you. I love having friends with three boys (even if I don't have the little girl of an exclamation point at the end). :)
(I think I've told you before, but my Owen has the same star hoodie with the purple lining = mini teenager. Love.)
xo e.
Nice reminder and adorable cowboy!ReplyDelete
Such a cute picture, completely frame worthy!
I love that quote, so true! I couldn't help but Tweet it. Have a great day :)
Boys! Love them.
What a great shot. It speaks volumes.
Love. This.
I will be adopting it pronto.
So handsome. And such a great reminder for siblings.ReplyDelete
I love that saying. I need to instill that in my son. Love your blog!ReplyDelete
What a good reminder!!! Maybe I should remind my punks about that! Ha! Cute pic!ReplyDelete
Wow. Thank you for sharing the wisdom of that quote!ReplyDelete
He looks like a professional rodeo clown and I mean that as a compliment.ReplyDelete
Steph that is an amazing thing to teach your sons!ReplyDelete
Tis a good lesson indeed!ReplyDelete
I love that. You're such a good mom. You have a cute cowboy too!ReplyDelete
awesome photo !!!ReplyDelete
another mom says........amen amen amen!!!!
Another woman says..........amen amen amen!!!!!
another person says................amen amen amen!
AMEN.....that's all we want for those we raise and come in contact with.....understanding of this, promote strengths, speak loudly of strengths.......pray quietly about weaknesses, be strong enough to promote someone else's weaknesses and allow those weaknesses to be there! IN the weakness is us allowing God to be our strength!!!!!!! Even for our family!
I love that you have "western day" at your school in the Midwest! ;) He looks pretty authentic too...
And that thing that you tell your boys, is going to be written out and plastered to our fridge. Perfect.
This quote touched my heart today it was exactly what I needed to read. Thank youReplyDelete
Such a good thing for all of us to learn!
Thank you for this. I've got two girls, but I think the prayer applies.ReplyDelete
What a wonderful thing to imprint in your boys' hearts and minds. I think I will say the same thing to my girls when they get a little older.


text:
Shamrock Sundaes RecipeRead Reviews Be the first to add a review
If your family loves ice cream (and who doesn't?), you'll probably serve these sundaes-with their from-scratch chocolate sauce-often. But you won't mind, because they're so simple to put together.
- 1/4 cup butter, cubed
- 1 ounce unsweetened chocolate
- 1 cup sugar
- 1/3 cup half-and-half cream
- 1/4 cup corn syrup
- 1/2 teaspoon vanilla extract
- Mint ice cream
- In a small saucepan, melt butter and chocolate over low heat. Add the sugar, cream and corn syrup; bring to a boil, stirring constantly. Boil for 1 minute. Remove from the heat and stir in vanilla. Serve warm or cool over ice cream. Yield: about 1-2/3 cups chocolate sauce.
Originally published as Shamrock Sundaes in Taste of Home Meals in Minutes Calendar Annual 1996, p9
Reviews for Shamrock Sundaes
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Any changes to your rating or review will appear where you originally posted your review


text:
The «La Côte» region extends from Morges to Nyon. the hilly landscape between the Jura and lake is one of the biggest wine-growing areas in Switzerland. Particularly between Aubonne and Rolle there are great many typical wine-grower villages, such as Féchy.
Morges once upon a time was an important commercial centre. For this reason a port, which nowadays serves as a port for yachts, was built at the end of the 17th century. The promenade along the lake shore of Morges stretches from the castle all the way to the Vertou Park and offers a fantastic view of the lake and Savoy Alps.
Morges Castle which was built in 1286 by Ludwig of Savoy houses several military-historic museums, including the museum of historic pewter figures with 10'000 figures. The Alexis Forel Museum located in a historic building in the town which houses a dolls and toy collection as well as an ensemble of furniture from the 16th to the 19th century is also well worth visiting. The Paderewski Museum is dedicated to the musical heritage of the Polish statesman and pianist.
The Bière-Apples-Morges railway line carries its passengers out of the town to the countryside which can be explored on foot or by bike. Several hiking trails which lead across fields, vineyards and forests thread through the region. A popular leisure park with a variety of attractions is located on the «Signal de Bougy» hill above the vineyards of Mont-sur-Rolle and Féchy.
The small towns and villages of Rolle, Aubonne, Vufflens-le-Château, St. Prex, St. Sulpice and their Romanesque churches are worth visiting. Most of the places have museums or other sights. Regular ship services, including paddle steamers, regularly pick up from embarkation points along the Swiss and French shore. Or you can explore the Lake Geneva landscape on special trips on a new galley which is a copy of the 17th-century original.
- Old town – the car-free Grand-Rue of Morges is perfect for a spot of shopping, and there is a market with local produce every Wednesday and Saturday. The lakeside promenade offers a fantastic view of the lake and Savoy Alps.
- Castle – the castle houses four museums: The Vaud Military Museum, the Swiss Museum of Historic Pewter Figurines, the Artillery Museum and the Vaud Police Museum.
- Alexis Forel Museum – the historic home with furnished salons houses decorative works of art, dolls and toys.
- Paderewski Museum – houses furniture, objects and archives of the pianist and Polish statesman Ignacy Jan Paderewski.
- Wine Road – Morges, the capital of Vaud wines, is the most important wine producer of the canton. Along the La Côte Wine Road visitors can find out about the jobs and products of the wine industry.
- City Golf – this mixture of mini-golf and Swin-Golf is an ideal way for groups and families to discover the city.
- Bolle Foundation – iconographical exhibition with over 4,500 engravings, postcards and photographs. Special exhibition to honor the memory of Audrey Hepburn, the actress who lived for 30 years in nearby Tolochenaz.
Top Events
- Tulip Festival – once a year Morges becomes the capital of tulips and the park is filled with tulips, narcissi and hyacinths competing for attention (April/May).
- Iris and lily garden at Vuillerens Castle – over 300 types of irises (about May/June) and day lilies (about July/August) grow in an area of over 200 hectares.
- Morges-sous-Rire – Western Switzerland's comedy festival in Morges (June).
- Dahlias on the Promenade – year after year, visitors are stunned by the fine display of thousands of dahlias between the Temple and Parc de Vertou (July to October).


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CRU THE DWARF: Moving to WordPress
cru on Feb. 15, 2015
>>CRU THE DWARF is now on WordPress<<
With the 2015 comic reboot comes a new, better site. Cru the Dwarf's new location at WordPress brings updated versions of old comic pages that fix the brightness/contrast and sharpness issues of the originals for crisper, easy-to-see versions of the classics. Not only that, the new site will contain the latest comic pages featuring the new HD character models that came with the World of Warcraft: Warlords of Draenor expansion.
The Duck (AKA DrunkDuck) has served Cru the Dwarf well for many years, but with the loss of page statistics and custom HTML I am limited in what I can do here as opposed to the host of features that WordPress offers, mainly the ability to keep track of visitor statistics and allowing viewers the freedom to comment without having to sign up - something DD has never offered. The comic archives will remain hosted here for some time until I see fit to delete them and leave only this notice page of the comic move.
For those DrunkDuck members who remember Cru the Dwarf from the good ol' days I encourage you to make the move with Cru over to WordPress where all new content will be posted, along with (eventually) the fan service works and the highly anticipated Frozen Desire mini comic, along with the old classic Yar Yar Hump Hump.
You can help by sharing the news with your friends, guild members, posting to your social media sites and spreading the word so Cru the Dwarf can return to its former glory.
There are many who forgot the comic, believing it to be dead and buried for years. In fact it was dead after real life had gradually taken more and more priority over this side project until it lay abandoned for several years. Those who kept it alive in their comments archived by the Internet and in their memories are what brought Cru the Dwarf back to life. It's the support I never really realized I had all those years ago that made me resurrect something that so many enjoyed. It was the fans who kept Cru the Dwarf going and it was the fans who are responsible for its return.
Starting out and growing on DrunkDuck has been a blast, but now that Cru the Dwarf has faded into obscurity here, where once it was consistently in the top spots, it's now time to move on to bigger and brighter pastures. Check out Cru the Dwarf on WordPress, bookmark, subscribe or whatever you want to do to keep up-to-date with the highly anticipated return of one of the best WoW comics whatever was.
See you, space cowboy…


text:
By Duane Pemberton
Winery website: http://doublecanyon.com
Double Canyon is a new winery in the state of Washington whose initial release is a Cabernet Sauvignon. It sources fruit from the prized Horse Heaven Hills AVA, which is home to some of Washington's better vineyards as well.
Using land that was originally owned by Don and Linda Mercer, the Double Canyon vineyard site is now in the hands of William Beightol. William has been tending to this area since he was a kid, literally, as he grew up across the street from where the Vineyard is at today.
Technical Data:
- Appellation: Horse Heaven Hills
- Vineyard: Double Canyon
- Blend: 85% Cabernet Sauvignon, 15% Syrah
- Alcohol: 14.5%
- Cooperage: 20 months in French oak; 35% new
- Price: $40
On the nose: Ripe raspberries, cherries, clay, herb, peppercorn, leather and cocoa.
On the palate: Very soft tannins for such a young wine and comes across as an "old soul". There's a nice combination of red fruits, soil, forest floor and some herbaceousness going on here. Good acids (as is the case with most all of the 2010 Washington Reds I've had so far), enticing fruit, and approachable tannins make for a very solid Cabernet.


text:
An offensive tweet about AIDS in Africa created a firestorm over the weekend and ultimately cost public relations executive Justine Sacco her job. Check out eight lives changed by the popular microblogging site.
Tracking Matthew
Eight lives changed by TwitterUPDATED 2:43 PM EST Dec 26, 2013
Slideshow Central
CommentsThe views expressed are not those of this site, this station or its affiliated companies. By posting your comments you agree to accept our terms of use.blog comments powered by Disqus


text:
Expanding Use of NGS Has Largely...
As Immunotherapy Revolutionizes the Cancer Treatment...
Wall Street Decline Takes Its Toll...
Developers of DTC Genetic Testing Are...
While approval of new therapeutic antibodies has not progressed as rapidly as was forecast 10 years ago, new products are moving through the pipeline. As always, bioprocessing, critical to antibody manufacture, is a key factor in the cost and efficiency of production.
Interviews with company officials and researchers engaged in bioprocessing showed how novel approaches to these challenges are moving the industry forward. All of the experts GEN spoke to will discuss new scientific developments and recent technological advances at BIT's "International Congress of Antibodies" meeting in Beijing later this month.
"We have more than 60 programs in progress with our partners; the majority of these programs are building on IgG-type antibodies," states Bodo Brocks, Ph.D., director and group leader of analytics and head of quality control at MorphoSys. "This is our preferred direction and our customers' favored format. Moreover, our high-throughput systems are designed to move in this direction, producing large quantities of antibody."
HuCAL, Morphosys' antibody-development platform, HuCAL, is a phage display technology consisting of a library of 40 billion possible human antibody sequences. Unlike earlier antibody-development platforms, it does not rely on immunization of mice or other animals.
In a typical run, a panel of a few thousand possible candidates can be selected and further analyzed. "We examine biological potency, specificity, and affinity of the antibody, while on the other side we look at the physical chemical properties like thermal stability or aggregation to make the antibodies fit for our pipeline," explains Dr. Brocks.
The antibodies from the library can be reconfigured, removing and replacing pieces so as to change their binding affinity or biological function without changing their overall human structure. "The strength of our technology is that we can do affinity maturation, bringing antibodies from nanomolar to picomolar affinity. By grafting alternative complementarity determining regions into promising candidates, we can develop highly potent antibodies."
Alternative scaffolds, based on protein families such as the ankyrins, have been the subject of considerable attention in recent years but have not yet resulted in FDA-approved products. "These are interesting from the standpoint of ease of production in bacterial systems," Dr. Brocks adds, "but in recent years mammalian upstream systems have improved significantly for antibody production, so that's not an area that we are pursuing at this time."
"We are moving from the era of blockbuster drugs to that of niche busters," says Paul Chapman, Ph.D., vp at EMD Millipore. "There's probably not a single antibody production company that doesn't carry over capacity based on business plans developed in the last decade."
The implications of this transformation within the bioprocessing industry, especially with respect to antibody production, are portentous. A decade ago many pharmas and biotechs built large-scale antibody-production facilities with elaborate and costly hardware for the purpose of generating kilogram quantities of a single recombinant protein.
Now much of this capacity is idle, as demand has shifted due to the pursuit of therapies guided by the demands of personalized medicine, in which the amount of material required to meet the needs of a restricted market may be orders of magnitude less. EMD Millipore is one of a number of companies developing single-use processing systems and technologies to meet this exigency.
Single-use modules are ideal for therapeutics whose demand will be measured in milligrams to kilograms rather than tons. "In moving from the lab bench to the bedside, we are deploying a range of single-use technologies for antibody manufacture," Dr. Chapman continues. "This allows us to remove labor-intensive steps and obtain the same quality with a much higher level of flexibility and overall plant productivity."
According to Dr. Chapman, the Mobius CellReady 3L Bioreactor is the first single-use benchtop bioreactor designed to mimic the characteristics and performance of traditional glass stirred-tank bioreactors. The Mobius CellReady bioreactor reduces turnaround time from days to hours, improving operational efficiency and scheduling flexibility for process-development labs.
Currently, cost savings are a significant consideration for antibody-production companies. "Earlier on, I don't think companies were that hard-pressed to optimize every step as the industry is today," Dr. Chapman suggests. "But now we can shrink the template and remove labor-intensive steps, while still retaining the same quality and manufacturing capacity. This means that we can drive down costs with a faster turn-around time. Moreover, we can run two to three different products at the same time, which would not have been possible without the flexibility of these single-use processing technologies."
K. John Morrow Jr., Ph.D. ([email protected]), is president of Newport Biotech and a contributing editor for GEN.
K. John Morrow Jr., Ph.D. ([email protected]), is president of Newport Biotech and a contributing editor for GEN.
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Lean-To Trellis
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- Oversized trellis supports big, tall plants
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Product Details
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Step #1 - Read All About It!
- Learn about the entire UA system. Visit the Planning and Institutional Research web site to check out UA in Review.
- Learn about UA's current issues by viewing Shaping Alaska's Future.
- Start preparing your professional resume.
- Get involved in Student Leadership opportunities on your campus.
- Read The Young Guardians. A field guide for student board members.


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Top Definition
When instead of taking a full shower/bath, you simply wet a washcloth and add soap, and then proceed to lightly scrub your entire body. Rinsing the washcloth periodically is vital to success as most if not all of the soap needs to be removed before a successful 'bath'.
Damn baby, that was some good sexin. Here's some washcloths, go give yourself an okie bath.
מאת Shirley Trooper 10 ביולי, 2008
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WISN 12 News has learned that bankruptcy papers have been filed after a Waukesha dairy plant abruptly closed last weekend.
Open Gate Capital, a California investment firm that purchased the Golden Gurnsey Dairy last year, filed the Chapter 7 bankruptcy paperwork in a Delaware court Tuesday afternoon.
The dairy operations were abruptly halted Saturday morning, leaving more than 100 workers out of a job and filled with questions.
The Wisconsin Department of Workforce Development said it did not receive the required 60-day notice for closing a business and has launched an investigation based on a complaint filed by one of the workers.


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We reported earlier this week that Porsche is looking to add
what is essentially "cruise control on steroids" to its future
vehicles. The Porsche
ACC InnoDrive system will take full control of throttle inputs and
"learn" the routes that the driver regularly travels. Only the
steering will be left for the driver to control when the system is enabled.
Now, we're getting some more information on the most famous
member of the Porsche family: the 911. The next generation model will be
revealed before the end of this year, with production models going to North
American customers next year.
The new 911, codenamed 991, is growing in length again. The
911 will sit on a 4-inch longer wheelbase, while overall length grows another
2.2 inches. Compared to the last air-cooled 911, the iconic 993, the new 911
is roughly 10 inches longer with a 7-inch longer wheelbase.
Despite the expanded dimensions, the new 911 will be lighter
than outgoing 997 variant. Instead of relying primarily on steel for the
construction of the vehicle, the majority of the vehicle will now be
constructed of aluminum with high-strength steel being deployed used for
"major crash paths" according
to Inside Line.
The extended wheelbase will also leave more legroom for the
two rear-seat passengers (in reality, kids only) and for an optional
hybrid system that should be available for the 2016 model year refresh of
the 991 platform.
The hybrid system isn't the only concession being made to
improve fuel efficiency for the 911; Porsche has also done the unthinkable and
ditched the 911's wonderful hydraulic steering system for an electric one.
Porsche 911 project manager Roland Achleitner explains that the excellent
steering feel will remain and that "you would not be able to tell it is
electric." Another buzzkill is that Porsche is moving to an electronic parking brake for
the new car.
When it comes to powertrains, the new 911 Carrera will share
a 3.4-liter flat-6 engine with the Boxster S that produces 350hp. The Carrera S
will be blessed with a larger displacement flat-6 producing roughly 400hp.
Power will be delivered to the rear wheels (or all four wheels in Carrera 4
guise) using a 7-speed dual-clutch (PDK) transmission or -- wait for it -- a 7-speed manual transmission.
Overall efficiency is said to improve by 12 to 15 percent
over the outgoing model.
For more information on the next Porsche 911 and the
development of the car, you can check out Inside
Line's write-up. They actually
got some passenger-seat time with a prototype of the vehicle.
quote: - porsches are more efficient
quote: - porsches are more efficient, the latest GT3 RS 4.0 makes 500hp from a 4 liter flat-6; a corvette needs a 7 liter V8 to achieve the same power.
quote: torque is of course another matter,
quote: - the vette still uses leaf springs (!) in its rear suspension. holy crap.
quote: Even spending upwards of $120k, there's really nothing out there for that money that beats the ZR1 soundly.
quote: porsches are more efficient
quote: the vette still uses leaf springs (!) in its rear suspension. holy crap.
quote: C6 Z06 with similar performance to many 100k+ Porsches and get another car or truck to use.
quote: Sorry, but the current Porsche Turbo S destroys everything (ZR1 included)
quote: Someone that will go on and on about the numbers a C6 will produce, while never admitting to its kit-car build quality and the fact that they will never, bla bla bla
quote: ever take it to an open track day and actually experience the thrills the car can give thanks to the numbers it produces.
quote: The whole point of a 911 is that people do drive them all-year round.
quote: 2) Vette has none of the comfort/German feel on the highway that the planted 911 has
quote: 3) Vette has none of the prestige of the 911
quote: 5) While it may lay down great times at the Nurbugring in the hands of a professional driver
quote: the Vette is a handful to drive at the limit in real life.
quote: 6) You buy a Vette because all you care about is 1/4 mile times.
quote: At the end of the day the Vette just feels like a cheap car that can go very fast but lacks the refinement found in competing vehicles like the 911, R8, GTR.
quote: I know you live in Canada and have a distant view of our country.
quote: While it may lay down great times at the Nurbugring in the hands of a professional driver, the Vette is a handful to drive at the limit in real life. In other words, in the hands of an average driver, you'd kill yourself in a Vette on a track if you pushed it hard and would never be able to match the times of the modern sophisticated cars like the 911 or the GTR.
quote: I though Porshes looked dated in the 80's. Now they look downright ancient. That's my opinion, and one that I've made with my wallet. I'll keep my Corvettes.


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Nightlife Photos
Bowl and dine at Bowl and Barrel
Photo: Stan Olszewski/Staff Photographer
Guests bowl and dine at the Bowl and Barrel grand opening VIP party in Dallas on December 5, 2012.
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Serves 5 |
Prep Time 1 hour 5 minutes |
Cook Time 0 minutes
1 piece Eden Pickled Daikon Radish, 5 to 6 inches long, rinsed and sliced thin
1/4 cup water
1/4 cup Eden Apple Juice
2 Tbsp Eden Barley Malt Syrupor organic maple syrup
1 Tbsp Eden Brown Rice Vinegar
Combine water, apple juice, barley malt and vinegar together. Stir to thoroughly mix. Place the pickle slices in a small bowl or jar. Pour the liquid over. Cover with cheesecloth or a thin towel. Place on the counter and allow to soak for 1 hour. Remove the slices and eat as is together with cooked organic grains, or as a filling for rice, vegetable or noodle sushi.
Condiments & Pickles, Eastern, Fruit, Japanese Food, Low Calorie, Low Fat, Macrobiotic, Sweeteners, Vegan, Vinegars, Wheat-Free


text:
Event Details
Date: March 21, 2014
Time: 12:30 pm
Add to your calendar
Location: Show map
Mandel JCC, Boynton Beach
8500 Jog Rd
Boynton Beach, FL 33472
Phone: 561-740-9000
Israel & the Middle East
A history of Israel and other forces in the Middle East are discussed and documented. Since there are problems and issues in the region, the potential causes and solutions will be debated. What is the effect of radical Islam on the region?
> Fridays; 12:30 pm; February 28, March 7, 14, 21
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Charleston Police Chief Greg Mullen is not pleased.
Despite the state Legislature's apparent enthusiasm for doing away with concealed-weapons permits, Mullen says, "I think it's a bad idea."
This isn't a surprise. Mullen attended a public hearing last month in North Charleston for a different bill that would allow concealed-weapons permit holders to bring their weapons into businesses, including those that serve alcohol, as long as there's no sign forbidding it.
When Mullen suggested that the bill could put police officers on the streets in danger, reporter Bo Petersen noted that the chief won only "respectful applause" for that.
Sounds like he would have been even less welcome in Columbia this week, when senators talked about eliminating the concealed-weapons permit process entirely.
"I feel this puts every law enforcement officer in jeopardy," he said.
Training, schmaining
The state requires a minimum of 40 hours training for people to drive.
If you were born after June 30, 1979, the state DNR requires you to complete an eight-hour hunter-education course before you can get a hunting license.
And of course, police officers must have regular firearms training, a requirement that apparently hasn't yet come up for discussion, presumably because legislators at least want the police officers to be better shots than the criminals.
It's not like the requirements for a permit — eight hours of certified instruction and a $50 registration fee to SLED — are all that excruciating.
And apparently it wasn't that big a deal for the 39,311 people who were issued permits in 2011 and the 14,650 who renewed permits that year, the latest data available on the SLED website.
Why bother with all that red tape?
Two words: Alice Boland.
Room for compromise
Mullen has carried guns all his adult life, first in the military and now as a police officer.
"I am a believer in the Second Amendment, but I'm also a believer in community safety. I also understand that there's many constitutional rights that we have that have limitations and restrictions that have been placed on them as people have determined a reasonable balance between personal freedoms and public safety."
Apparently not everybody shares the chief's views.
Certainly not Spartanburg Sen. Shane Martin, who said this week that he was disappointed that law enforcement officials would speak out against gun rights, or as he put it, "God-given constitutional rights."
Mullen found it odd that someone who is supposed to hear opinions from all sources would then chastise people, including police, for simply giving their opinions.
Of course, this wouldn't be the first time our legislators went through what's supposed to be a public process with a predetermined agenda.
"The argument that bad people carry guns so good people should carry guns, a lot of times, good people become bad people because a gun is introduced into the situation," Mullen said.
Hopefully state leaders will realize that's not good for anyone.
Reach Melanie Balog at 937-5565 or email@example.com.


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The E! News host and Fashion Police cohost, 37, whose road to motherhood has been made difficult by infertility struggles, one miscarriage and a diagnosis of breast cancer, announced in person Monday on the Today show that she is expecting.
"We are so thrilled that our prayers have been answered," Giuliana tells E! News. Adds Bill, 40, "We are absolutely ecstatic to be sharing this with everyone who has been following our journey."
The child is due in late summer via a gestational carrier, meaning that the Rancics will be the genetic parents. They know the sex of the child, "but we're seeing how long we can keep it secret," Giuliana said on Today.
She aded that the surrogate mother lives out of state, but that they accompany her on all the visits to the doctor.
The couple's desire to have children played a part in Rancic's decision in December to undergo a double mastectomy. The years of medication that typically follow a lumpectomy and radiation therapy would have meant delaying parenthood for several more years.
At the time, Rancic said she was crushed by her 2010 miscarriage. "I said, 'I'm not doing this again. I can't.' I was angry at life and at God," she admitted. But the couple decided to press on again with in vitro fertilization.
Each step of their lives has played out quite publicly, in part because it's all documented on their Style Network reality show, Giuliana & Bill, currently in its fifth season.
Visit msnbc.com for world news, and news about the economy


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I'm really excited to share a great book by cooking & entertaining guru Erika Lenkert as part of our giveaway today! It's called The Last-Minute Party Girl and is a fun, ultra-hip, how-to read that's full of fabulous advice, witty anecdotes, and tons of great recipes. Here are just a couple of the of many rave reviews for The Last-Minute Party Girl :
"The Last-Minute Party Girl puts the FUN back into FUNctions. It's a lively resource for those who like to entertain with style, but don't have the time (not to mention the pocketbook) to turn a simple soiree into their raison d'etre for a month."
– Glynis Costin , Party Girl, Mother of Two, and West Coast Bureau Chief, In Style Magazine
"Erika Lenkert's recipes for tossing fabulous parties are equal parts sexy, sweet, spicy, and sassy. With hilarious stories and an insider's approach, The Last-Minute Party Girl is the ultimate handbook for hosting the perfect party."
– Peter Davis , Editor at Large, Paper Magazine
The book's 10 chapters include things like Party Girl Etiquette, Vibe by Design (setting the scene), Painless Party Planning, A-List Appetizers, and The Party-Girl Pantry (survival supplies & shortcuts that will keep you stocked & prepared for even unexpected gatherings).
And speaking of supplies , you're going to need something to help you stock up on some party girl must-haves of your own… so how does a $100 gift card to cb2 or Crate&Barrel sound?!
FIRST PRIZE : Author-signed copy of The Last Minute Party Girl + a $100 gift card to your choice of cb2 or Crate&Barrel
SECOND PRIZE : Author-signed copies of The Last Minute Party Girl for 4 more lucky readers
• Post a comment here. Tell us what you'd spend your winnings on, share your own favorite party advice, or just say anything!
• Enter by Thursday, April 17th at midnight PST. Be sure to login or include your email address (won't be published) so that we can contact you if you win. Good luck!
Comments 700
- posted in:
- In the Spotlight
1Susan SAYS:
Sounds like such a great book! I'd love to win a copy!
2MB_in_DC SAYS:
I love throwing parties – a friend and I just threw a wonderful baby shower for one of our neighbors, I used several ideas I picked up on this site! 2007 was a really rough year for me and so far 2008 has been a great year for new beginnings, one of the things I look forward to the most is the first dinner party at my next new place. Hopefully soon.
3Kelly R. SAYS:
Yes, Please!! Love the sound of "the party girl pantry" chapter. As I'm newly married and just starting to get into the world of entertaining, that's definitely something I could stand to learn more about!
4rita t. SAYS:
ooh! I would definitely be taking my winnings to Crate & Barrel! Great giveaway!!
5Tiffany SAYS:
This really sounds like a great book! And i love both of those stores – choosing one would be a tough decision!
6Kate SAYS:
ooo! I love cb2, I would definitely spend my winnings on some new summer entertaining drinkware and acessories!
7Anonymous SAYS:
I would love to win this… I would probably spend the $$ on some new seasonal items to jazz things up- napkin rings, tablecloth, platter, etc.
8kira SAYS:
Fabulous! I would love to get some new outdoor entertaining goodies for summer!
9Heather SAYS:
The Last-Minute Party Girl sounds like it could give me the inspiration to inject spontaneity into my over-scheduled life! My boyfriend and I have been fantasizing about getting some decent barware from cb2. I would absolutely love to win.
10Valerie SAYS:
I would love to win!
11Nicole SAYS:
I will soon be moving into my own place and I can't wait to start entertaining. My winnings would most likely be spent on some great cocktail glasses. Nothing like a pretty glass to drink out of!
12Joseph SAYS:
I'd spend my winnings on a Mother's Day party.
13SuzyQ SAYS:
My party advice to have everything prep in advance – make things you can made a few days ahead of time and freeze before your party – less stress and less mess on your actual party day.
14j SAYS:
That book looks so cute!
15Brittany SAYS:
What a great giveaway. My law school graduation is quickly approaching; this book and the gift certificate would be so helpful in planning an appropriate celebration!
16Patty SAYS:
I love CB2, thanks for the opportunity to win.
17Angie SAYS:
Fun stuff! I would buy some new bedding for my drab (and sad) bed!!
18Kristie Burke SAYS:
party! party! party! party! party! YAY! party! party! party!
19andrea SAYS:
Summer is my favorite time of year for evening parties. We always re-use our white christmas lights at this time and the back yard looks so pretty!!
20lauren SAYS:
Oh dear, I LOVE cb2! Although I'd probably end up spending my winnings on my best friend who just moved into a new house. Or maybe on stuff for me to throw her a party :)


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PITTSBURGH - The Steelers needed a hero Monday night.
They lost their offensive and defensive leaders to injuries and were already playing without four starters. They also were struggling to beat a 1-7 team they were supposed to crush.
Linebacker Lawrence Timmons hasn't produced many memorable moments in his six-year NFL career, but he came through in the clutch for the Steelers late Monday.
Article Photos
Mirror photos by J.D. Cavrich
Ben Roethlisberger is sacked by Kansas City Chiefs defenders Justin Houston and Tamba Hali. He left the game after the hit and did not return.
Timmons intercepted a Matt Cassel pass on the second play of overtime and set up the game-winning field goal to help the Steelers pull out a 16-13 victory over the lowly Kansas City Chiefs at Heinz Field.
The Steelers improved their winning streak to four games and are now 6-3 with a battle with the AFC North-leading Baltimore Ravens looming next Sunday night.
"I was basically dropping back in coverage,'' Timmons said. "Our defensive line did a great job all night getting pressure on [Cassel], and it caused him to rush his throw. I was there to make the play and caught the ball and made the play.''
Cassel was trying to throw to Dwayne Bowe, but Timmons picked the ball out of the air at the Kansas City 28-yard line and returned it to the 5. Shaun Suisham was immediately sent out onto the field and booted the game-winning, 23-yard field goal.
"The guys made the necessary plays to get out of the stadium with the win,'' Steelers coach Mike Tomlin said. "Big-time kudos to all of the people that made the necessary plays, particularly Lawrence Timmons, who made a big play there for us in overtime.''
Timmons' heroics were needed mainly because players like quarterback Ben Roethlisberger and safety Ryan Clark were not on the field due to injuries. Their playing statuses for next week's game against Baltimore are now in doubt.
Roethlisberger sustained a right shoulder injury in the third quarter and was being evaluated after the game, according to Tomlin. He was replaced by Byron Leftwich. Clark was being evaluated for a concussion after he hobbled off the field late in the fourth quarter.
"Obviously, those two men are critical to our efforts here moving ahead,'' Tomlin said.
The Steelers were already playing without dynamic receiver Antonio Brown, All Pro safety Troy Polamalu, running back Rashard Mendenhall and right tackle Marcus Gilbert.
But the team pulled together to beat one of the worst teams in the league.
"We just stayed positive,'' Timmons said. "It's easy to try to get down on yourself, but we are not like that. We stand up, face adversity, and this defense did well.''
The Steelers spotted the 12 1/2-point underdog Chiefs an early 10-0 lead. Kansas City, with the help of a Cassel-to-Tony Moeaki 38-yard pass, traveled 70 yards in four plays and grabbed a 7-0 advantage on Jamaal Charles' 12-yard touchdown run.
Later in the first quarter, Steelers running back Isaac Redman fumbled the ball at his own 9-yard line, and the Chiefs' Allen Bailey recovered it. Ryan Succop then kicked a 22-yard field goal at the beginning of the second quarter.
The Steelers got back into the game when they inserted Jonathan Dwyer into the backfield after Redman's fumble. They started at their own 40-yard line and made it to the Kansas City 17 before Suisham's 35-yard field goal gave them their first points of the night.
Dwyer then broke off runs of 6, 17 and 6 yards, and Roethlisberger took off on a 14-yarder to move Pittsburgh to the Kansas City 7. Roethlisberger then fired a fade pass to Mike Wallace in the back corner of the end zone, and Wallace made a one-handed rolling catch that stood up after a video review and tied the game at 10-10 at halftime.
The Chiefs were their own worst enemy in the third quarter. A holding call against left tackle Branden Albert nullified a 22-yard touchdown reception by Bowe. Four plays later, Succop missed right on a 33-yard field-goal attempt.
The Steelers then were helped by two Chiefs penalties on a 73-yard drive that lasted into the fourth quarter. Cornerback Javier Arenas was called for pass interference on Emmanuel Sanders to give Pittsburgh 22 yards on third-and-3, and linebacker Tamba Hali was whistled for roughing the passer on third-and-12 at the KC 27.
Eventually, Suisham gave the Steelers a 13-10 lead with 12:37 left in the game with a 31-yard field goal, and it appeared as though the Chiefs' spirit had been broken.
But Kansas City managed to put together a two-minute drive in the final moments of the game. Cassel connected to Moeaki on passes of 18 and 12 yards to get to midfield. Cassel then found Bowe for 27 yards on a fourth-and-15 play from the KC 45.
Succop then was good from 46 yards away as the clock expired to send the game into overtime.
"[Kansas City] is a tough team,'' Timmons said. "I wouldn't say we were looking ahead [to Baltimore]. This is the NFL. You are playing against great talent every week.''


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The Kennedy Space Center Visitor Complex has been invaded by Angry Birds.
The brand new attraction based on the popular video game opened Friday morning.
Guests to the Angry Birds Space Encounter can dodge lasers, put together Angry Birds puzzles and play the popular game.
Astronaut Don Pettit, who helped develop the Angry Birds in Space game while he was in space, spoke about how guests can learn about things called elliptical trajectories, hyperbolic trajectories and parabolic trajectories.
The attraction will take up almost 4,500 square feet at the visitor complex.
Executives said they plan to have Angry Birds around indefinitely.


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Is Pennsylvania next right-to-work battleground state?
January 29, 2013
There was Wisconsin. Then there was Michigan. Could Pennsylvania be the next right-to-work battleground state? Speaking to 84th District constituents at a town hall meeting last week, state Rep....
The S-G editorial staff sure doesn't know what they are talking about here. Again, RTW states are poor. Mike Kerstetter wrote the other day how Mississippi, a RTW state has the lowest median income in the states.
Since wages are low, tax revenues are low and those states tend not to invest in education. Check out Oklahoma-business leaders there are scrambling because they don't have the science and math talents to attract businesses.
Basically, what you end up with is an unskilled, poor, and undereducated workforce. What business would want to move to an RTW state?
1 Agrees | 0 Disagrees | Report Abuse »
IMHO, I certainly HOPE the fine folks of Pennsylvania READ 'all' the fine print of what it means to live in a "Right to Work" state. If it's just the glitz-n-glammer of union busting, then read a bit more. Having lived and worked in a few 'Right to Work' states, south of the Mason-Dixon for what seemed like a freekin eternity, you'll find yourselves with a rude awakening if you take 'Right-to-Work' at face value. It's much more than Just a union buster. It should be called the 'Right to Fire'.
1 Agrees | 1 Disagrees | Report Abuse »
Don't the "Republican Citizens" reap the same benifits as the "Democrat Citizens" with the current President.
Just saying ...
2 Agrees | 0 Disagrees | Report Abuse »
*that was supposed to say the people NOT in the union.
1 Agrees | 0 Disagrees | Report Abuse »
clw, is that really how you think it'll turn out? I don't.
While I see and do not necessarily disagree, with your point, at the same time, the people (at least some of them) choosing not to join the unions will scream discrimination or whatever you want to call it, it'll go to court and in the end, the unions will likely (but not guaranteed) lose. Denying someone the ability to 'advance' or the opportunity at the same position/wage based on a decision not to 'pay for it' will ultimately be considered a form of discrimination. That's just what I believe will happen. In the end the people in the union, will get the same benefits.
1 Agrees | 1 Disagrees | Report Abuse »
I say if they pass the right to work,if you choose not to join the union then you don't get the same pay rate or any of the benifits that the union fought for.Then maybe people will see what the unions have done for the working middle class,and union busting will end.
2 Agrees | 3 Disagrees | Report Abuse »
If Right to Work is a campaign to destroy unions it is failing miserably since there are several states in which Right to Work has passed and it still has more union members than neighboring Non Right to Work states. In fact, Right to Work is about two things....personal freedom and economic prosperity!
4 Agrees | 1 Disagrees | Report Abuse »
I understand that Republicans are pushing this and I understand it's because they feel it gives them a political advantage, however, I still, as a democrat, believe we should be a Right to Work State.
4 Agrees | 3 Disagrees | Report Abuse »
Right-to-work is a campaign to destroy the unions because they tend to support democrats. Look at who supports this legislation.
3 Agrees | 6 Disagrees | Report Abuse »
I'm absolutely in favor of PA being a Right To Work state. I'd vote for it in a heart beat. I do believe that workers should have the Right to choose between being a member of a union or not. Should they be given the benefits of a union if they choose not? Well, no I don't think so because every positive choice still has it's cons and vice versa. You just have to choose what you believe is best for you individually. But joining a union isn't always the best choice.
5 Agrees | 3 Disagrees | Report Abuse »
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Top Definition
The act of putting a dirty tube sock over your penis and face fucking a girl. Once you orgasm, you leave the sock in her mouth and walk away, but not before saying, "Have a nice day"
Did you hear Paul gave Sarah The Mick Foley last night? That shit was dope!
af Roogert O'Lollipops 8. august 2009
Trending Now
Can you define these popular missing words?
When a man puts a sock over his penis and crams it into his partners mouth, thus representing "Socko', where Mick Foley would put a sock over his hand and cram it into his opponents mouth, then win the match.
My girlfriend wanted to give me a blowjob, so I pulled off my sock and gave her The Mick Foley.
af S.P.G 10. juni 2011


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Mr. and Mrs. Terry Carr celebrated their 30th wedding anniversary on June 13.
The couple were united in marriage June 13, 1981, at Hart Chapel Church in Elkins. The Rev. Robert Lowther officiated.
Mrs. Carr, the former Brenda Kay Irwin, is a native of Elkins. She is the daughter of Fred and Mary Lou Irwin. She graduated from Elkins High School in 1980. She is employed by All Seasons Real Estate Service Inc. as a Realtor and office manager.
Mr. Carr, also a native of Elkins, is the son of Granville and Lola "Marg" Carr. He graduated from Elkins High School in 1978 and retired from Kroger in 2004.
They are the parents of one daughter, Mallory Carr of Martinsburg, a 2007 West Virginia University graduate who is employed by Berkeley County Schools in Martinsburg; and two sons, Brant, a 2011 graduate of WVU, and Ethan, a 2010 graduate of Blue Ridge Community Technical College who currently attends Shepherd University. They have two family dogs, Reggie and Bayley.


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Why Shia LaBeouf Is Hollywood's New King of Jerks
Ladies and gentlemen, Project Hollywood has succeeded. Decades ago, we constructed an artificial environment disconnected from humanity. Its only function was to create even more artificial scenarios even further disconnected from humanity. After billions of dollars, this philosofractal metamaze has realized its ultimate goal: an utterly oblivious human. A man with less self-reflection than Dracula. A man so geocentrically self-centered, he thinks the sun is a stage light constantly searching for his best side. A man so lacking in self-awareness, he's invisible to Zen Buddhists. A man who pushed the limits of assholing harder than Goatse. May I present: Homo Shia.
A man so incapable of self-examination, he thought this looked cool.
Shia LaBeouf recently stole the spotlight by stealing an entire screenplay. He "plagiarized" the script for his short film HowardCantour.com from Daniel Clowes' comic Justin M. Damiano, in the same way settlers "short-changed" Native Americans for the island of Manhattan. But he paid less. He stole the entire comic, scene for scene, line for line, word for goddamn word. It is impossible to overstate how directly he ripped it off. I've used photocopiers that make less direct reproductions.
Siri Stafford/Digital Vision/Getty Images
Shia at his writing desk.
When you read the title "HowardCantour.com," you've already experienced most of Shia's contribution to the project. The only other alterations were things like changing the bagels the characters eat into cookies. That's the level of cinematic insight Shia brings to a creative project: liking cookies.
Creatas Images/Creatas/Getty Images
"I go to my death shamed by association."
He also changed a mention of Le Mepris to Shakespeare in Love, because he doesn't think a lifelong professional film critic would have heard of one of the most famous French movies ever made. No, he's really changing it because he thinks you're too stupid to know anything outside of Hollywood. It's possible he doesn't even know there is an outside of Hollywood and thought the original comic had a typo. Children have copied from Wikipedia 10 minutes before the school bus arrived and put in more original work, because they change some words other than the proper nouns. He couldn't have taken from Clowes more publicly, obviously, and brutally without cloning him and beating the result to death on stage.
He didn't even tell Clowes, and he took this film to the Cannes Film Festival. He stole an entire story, took it to one of the most famous display events in the world, and didn't think anyone would notice, because he thought moviegoers didn't care about comics. I repeat: The star of the billion-dollar Transformers movies thinks moviegoers don't care about comics.
On the upside, he's a much better actor in this one.
He made millions from an extremely licensed and copyrighted property and used some to fund another movie. That means he paid actors, camera people, truck drivers, even craft services, but not the writer. He thinks the person who cleared away the coffee cups on his movie deserved more money than the person who wrote it. He even has a credit for "Script Supervisor Sarah Horton," who I'm assuming was paid to help him with the big words when reading the comic.
Which is why from now on he's Chia LeBeef. If he can't be bothered to add the proper names to his work, then neither should we. Besides, getting his name wrong is probably the only way a human can wound this vapid famebeast on our mortal plane.
"I don't know, LeBeef still sounds too tough for someone who looks like me" -Mirror Universe self-aware Shia
No human has ever been so caught. History is littered with idiots who confused recognition with respect, but only Shear-a LobeOff stole so blatantly after we built a global communications network and then enjoyed the resulting attention. His response was a masterwork of every way you can invert an apology. He deeply regrets; he apologizes that we assumed he wrote the film that he talked about making for years and didn't credit anyone else for writing; he's "embarrassed that he failed to credit" the person whose lifetime of work and experience he lifted like a candy bar. Note how all the apologies are about his feelings, not his victim's loss. And he makes promoting a movie for years without once even telling the person who wrote it sound like forgetting to pick up milk at the store. But then, he does have experience being arrested for being a moron at the store.
"I deeply regret the manner in which these events have unfolded." He knows that sounds like a stupid fake robot taking the piss out of gullible viewers. That's his entire cinematic experience!
And even then his primary role was "taking shit that belongs to someone else."
In the same message, he insists that "Being inspired by someone else's idea to produce something new and different IS creative work." Which is true, just as "The lunar missions had to reach a velocity greater than 11.18 km/s to escape Earth's gravitational pull" is true -- it's still not something Xia has actually done. He might as well argue that the true beauty belongs to the eye of the beholder from behind the wheel of a stolen Lamborghini.
If he'd only worked this out with Clowes in advance, he'd be a hero. "Hey, Shia is trying to apologize by making good conversions of comics!" But this was never about making something new. This was about making Shia look smart and talented. But hundreds of millions of dollars of special effects and marketing have already failed at that.
He looks like he was malnourished by the YMCA and is revenge-mocking the Village People.


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Your pets step to flea control against fleas is a flea comb and a good bath. The Soap will act as a gentle insecticide and helps control light infestations on your pet.
Just letting the soap sit on the animal a few minutes will help loosen them and send them down the drain.
Though time consuming, combing helps reduce the need for insecticides and flea sprays on your pet.
Flea combs have fine teeth that remove adult fleas from fur.
Your pet will most likely enjoy the combing and attention they receive.
Pay special attention to the face and neck, and the area in front of the tail and around the ears.
Dipping the comb frequently in soapy water or an alcohol solution to kill fleas removed from the pet.


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ATTICA - Put in a position no coach ever wishes to be in, Jeremy Nutter admitted it was hard coming up with the right things to say to his players.
On Thursday, Hopewell-Loudon student Cameron St. Clair, a former football player, died. Less than a day later, his friends and former teammates were on the field trying to win a football game.
Nutter was asked if the Chieftains considered not playing Friday night.
Nutter paused before answering.
"If I know Cameron, and I think I do, I think he'd say to us that we need to get out here and play this game," he said. "These are kids; that's what they deserve, and I know their hearts are heavy, but it feels good for a little bit to be out here playing the game we love."
The Chieftains not only played, but played well, using a power running game and some big plays on defense to beat Seneca East in Attica, 27-19.
H-L (5-3, 3-2 Midland Athletic League) overcame a Seneca East touchdown on the first play from scrimmage. SE quarterback Ethan Caudill hit Brayden Walker for a 65-yard touchdown, giving the Tigers a 6-0 lead 16 seconds into the contest. SE missed the extra point.
But Hopewell-Loudon needed less than three minutes of game time to answer. A 36-yard completion from Derek Runion to Ryan Lommerse set up a Cody Malone touchdown, and the Chieftains took a 7-6 advantage.
Caudill went right back to work, marching the Tigers to the H-L 8. But on a first-and-goal, Caudill was intercepted by Zach Clouse in the end zone.
"At that point I had no illusions that we were going to keep them under 80 [points]," Nutter said of the SE offense. "It was a scary situation to be in, but we finally stepped up and made that play. Zach Clouse made a great play right there. He's one of our senior leaders."
Hopewell-Loudon went up 14-6 when quarterback Derek Runion faked a handoff to Malone and went 6 yards for a TD early in the second quarter.
Seneca East's offense again struck quickly. This time it was a 54-yard pass from Caudill to Alex Scheiber to make it 14-13 with about eight minutes left in the half.
Scheiber had 149 receiving yards at the half. Caudill had thrown for 223 yards. But the Tigers (4-4, 2-3) had only 13 points to show for it at the break. H-L led 14-13 at intermission.
"We had a couple plays ... we just left them on the table," Seneca East coach Ed Phillips said. "The table was set there to go."
In the third quarter, Hopewell-Loudon - and Malone specifically - picked away at the SE defense. The Chieftains took the opening kick of the second half and held the ball for more than seven minutes. No play went for more than 12 yards, but H-L methodically marched down the field, converting on a pair of third downs and using Malone for eight punishing runs. His final one, a 2-yard burst, put the Chieftains up 21-13.
"You're frustrated, because we just couldn't get them off the field," Phillips said.
The Chieftains weren't done. After forcing Seneca East's offense into a three-and-out, H-L ran eight more plays, keeping the ball as the quarter drained to its conclusion.
Final third quarter tally: H-L offense 21 plays, SE offense three.
Nutter said that was about the only way he knew to slow down the Tigers scoring attack.
"I don't know any other way to beat them," Nutter said, "except to not let them have the ball."
Three plays into the fourth quarter, Runion scored his second rushing touchdown, this one from 11 yards out, and the Chieftains went up 27-13.
The teams traded possessions over the next 4 1/2 minutes. With H-L driving and with the clock crawling under six minutes, it looked like the game was over.
But anyone who's seen a Seneca East game this season knows better. An errant shotgun snap was recovered by Walker, and three plays later Seneca East was in the end zone, as Caudill found a wide-open Scheiber in the end zone for a 7-yard score. The Tigers again missed the extra point, but were down just eight with a little more than five minutes remaining.
Seneca East's defense forced a punt, but the Tigers couldn't manage a first down, and H-L had the ball with 1:12 to go.
But Phillips had all three of his timeouts, and used them in consecutive plays. When Runion was stopped on fourth-and-1 with 52 seconds left, SE had one more chance. It started at its own 35.
"I just told these kids, they're such a high character group of kids, and they're never out of it," Phillips said.
But Lommerse stopped the rally, intercepting Caudill on the first play of the drive. Hopewell-Loudon ran out the clock and won.
"We needed that defensively, because (the Tigers are so difficult to defend)," Nutter said. "It seems like they've got 15 [players] out there instead of 11 sometimes.
"I had no sense of comfort whatsoever," he said. "But Ryan Lommerse made a heck of a play."
Lommerse had 83 yards receiving to go with his pick, and Runion threw for 202 yards. Caudill threw for 288 yards, and Walker had 102 receiving on just two receptions.
But in the end, what happened on the field was secondary.
"My heart goes out to [H-L's] community," Phillips said. "I told the kids after the game (the loss) is hard, but it's not as hard, but it's not as tough as what life will hand them."
"Our hearts are broken for Cameron's family," Nutter said. "Our our thoughts and our prayers go out to them."


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Partisan politics has so polarized America that normal, honest behavior seems to be the oddity that stands out these days. Much ado is being made of Gov. Chris Christie's common sense communication with President Obama during Sandy's aftermath. Christie and the president working together for the good of the citizens who elected them for that very reason is seen as spectacular when it should have been the ordinary, the norm.
The attack of our embassy in Benghazi, Libya, on Sept. 11,which resulted in four Americans being murdered, is now used as an opportunity to gain political points. Washington Republicans and the partisan pundits beyond have slapped on the war paint, donned the camouflage and are armed to the hilt—out to get Obama's blood at all cost.
Now there is loud clamor for transparency and investigations, accusations of a cover-up and incompetence, with those doing the talking all the while professing to only want the truth as concerned Americans and conscientious politicians. Give me a break. The only conscientious concern here is self-serving partisan BS.
Where was all that concern for our men and women serving in embassies and consulates across the globe when all the other attacks and killings occurred?
Like in 2002 when the US Consulate in the Karachi, Pakistan, was attacked and 10 were killed?
Or in 2004 when the US embassy in Uzbekistan was attacked and two were killed and another nine injured?
How about in 2004, when the US Consulate in Saudi Arabia was stormed and 8 lost their lives?
There is more: In 2006, armed men attacked the US Embassy in Syria and one was murdered.
Then in 2007 a grenade was thrown at the US Embassy in Athens.
In 2008, the US Embassy in Serbia was set on fire.
In 2008, bombings in the US Embassy in Yemen killed 10.
Notice the dates, all before the Obama administration.
Not yet convinced that all the noise over Benghazi has nothing to do with love of countryman? How about the biggest, most catastrophic attack and murder of Americans? As a New Yorker, Sept. 11, 2001, is indelibly imprinted on my psyche and I'm sure on the rest of the country. 3,000 perished in the most brutal act of terror in our recent history—all under a Republican administration. George W. Bush and his team had nine warnings that al-Qaida would attack within the United States, but they did absolutely nothing. No one in that administration's head rolled for that stunning incompetence.
But Republicans now want President Obama's head for Benghazi.
Here is an excerpt from the Ninth Public Hearing of the National Commission on Terrorist Attacks upon the United States, held Thursday April 8, 2004, where Bush adviser Condoleezza Rice, is being questioned:
MS. RICE: I remember very well that the president was aware that there were issues inside the United States. He talked to people about this. But I don't remember the al Qaeda cells as being something that we were told we needed to do something about.
"MR. BEN-VENISTE: Isn't it a fact, Dr. Rice, that the Aug. 6 PDB warned against possible attacks in this country? And I ask you whether you recall the title of that PDB.
MS. RICE: I believe the title was "Bin Laden Determined to Attack Inside the United States." Now, the PDB --
MR. BEN-VENISTE: Thank you.
Rice, in uncharacteristic obtuseness, for she is an academically brilliant and accomplished woman, gave the above unbelievable answer. We all now know they knew of imminent danger facing American citizens, but buried their head in the proverbial sand, ostrich style. (Read the official transcript on that hearing here: Thursday, April 8, 2004 - National Commission on Terrorism).
If you like writing about US politics and Campaign 2012, enter "The American Pundit" competition. Allvoices is awarding four $250 prizes each month between now and November. These monthly winners earn eligibility for the $5,000 grand prize, to be awarded after the November election.


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Expanding Use of NGS Has Largely...
Quadruple Helices Appear To Have Role...
LC-MS Gains Favor Due To the...
As Immunotherapy Revolutionizes the Cancer Treatment...
Samsung, the South Korean company best known to Americans for televisions and other electronic equipment, is branching out to make biopharmaceuticals. In May, ground was broken for Samsung Biologics located in Incheon, South Korea; full-scale operation is expected to start by January 2013. The plant will be fully equipped with cutting-edge technologies, such as 30,000 liter mammalian cell culture bioreactors. When fully operational, the plant will employ 200–300 workers.
In addition to electronics manufacturing, Samsung has divisions involved in construction, shipbuilding, textiles, finance, and medical devices, among others. "We are known for high-quality manufacturing of complicated materials, and we can bring our talents and technical confidence to manufacturing biopharmaceuticals," says Kyu-sung Lee, Ph.D., senior vice president at Samsung Biologics. Technologies that Samsung already excels at, such as hygienic piping, cleanrooms, HVAC, and quality control, are readily transferred to building and operating the biopharmaceutical facility.
The launch of the new biologics business builds on the company's past achievements. Its customer-oriented business model will, it says, bring collaborative drug-development and high-quality, fast-turnaround contract manufacturing to partners. "We will prove that we can deliver the quality and service shown by Samsung in other areas like electronics," says Dr. Lee.
The plant will focus on contract manufacturing of biopharmaceuticals for customers. Samsung also has its own R&D pipeline of monoclonal antibody candidates to treat cancer, arthritis, and other illnesses. "We will manufacture our own biologics when they are far enough along," explains Dr. Lee. The plant will operate under global GMP compliance, and products will be sold worldwide. "Having a plant in Asia makes it easier for clients to penetrate the Asian market."
The facility is a multiproduct plant that meets the requirements of the U.S. FDA and the EMEA. The plant accommodates minimum change over time between production runs to meet clients' targets. In addition to the production unit, the facility contains Samsung Biologics R&D center, an upstream suite, downstream suite, fill-and-finish suite, administrative offices, and a warehouse with long-term cold storage capacity.
Samsung Biologics will focus on mammalian cell culture. Services range from protein target purification, process development, and aseptic fill and finish for any scale, from preclinical quantities to commercial production. "We designed the facility to meet our manufacturing conditions and issues," noted Dr. Lee.
Cell-line development starts with DNA sequencing, clone screening and selection, and cell-line stability studies. Researchers at Samsung Biologics have extensive experience in working with many types of mammalian cell lines. The facility is custom designed for mammalian cell therapeutic monoclonal antibody production with maximum flexibility.
Core competencies in upstream development include selection and development of cell culture media on a flask scale; optimization using 1 to 5 liter bioreactors; and scaleup to 200 liters. Downstream process-development includes resin screening for chromatographic optimization and scale-down validation, and process characterization to improve a protein's therapeutic attributes. The filling suite is modularly designed to meet future additional pre-filled syringe, liquid fill, and lyophilization units.
The quality assurance (QA) division functions independently of all other operations to insure high-quality products and services that meet legal requirements and comply with regulatory guidelines. The QA specialists oversee proper release and/or rejection of raw materials, intermediates, and packaging and labeling of materials. They also approve all specifications, standard operating procedures, and master batch records.
Chemists, immunologists, and microbiologists in the quality control (QC) department will insure that high-quality products are made in a controlled environment. The QC team will test all manufacturing processes at various points, including raw materials and samples in process and released, as well as water systems and clean steam and gas supplies. All quality analyses will be conducted under strict GMP standards.
"Even though we have no history of biomanufacturing, we hired seasoned executives from the United States who know about biomanufacturing, technology transfer, and validation and quality control," says Dr. Lee.
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While Zika continues to garner a lot of news coverage, a Mayo Clinic survey reveals that Americans believe the country's most significant healthcare challenge is cancer. Compared to other diseases, does the possibility of developing cancer worry you the most?
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Mission: The International Studies and Study Abroad Program is designed to increase student awareness of and participation in global and cultural studies outside of the classroom and beyond the campus.
Advisory Council Members:
Betty Dickson, Ed.D.
Professor Early Childhood Education, Division of Education
Jonathan Hutchins, A.B.D.
Assistant Director, The Social Justice Initiative
Raphael Lewis, Ph.D.
Professor Department of Political Science, Division of Social Sciences
Teresa Ojezua, Head Librarian
D. W. Reynolds Library
Bertha Owens, M.A.
Assistant Dean Recruitment Admissions and Registrar
Hazel Arnett Ervin, Ph.D.
Ex-Officio Office of Academic Affairs


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The Asia-Pacific Trade and Investment Report (APTIR) is a recurrent publication prepared by the Trade and Investment Division. It aims to deepen understanding of regional trends and developments in trade and investment; emerging issues in trade, investment and trade facilitation policies; and impacts of these policies on countries' abilities to meet the challenges of achieving inclusive and sustainable development. APTIR 2012 focuses on trends and developments in the economies of Asia and the Pacific in their post-recovery from the 2008-2009 crisis and trade collapse.
Falling demand in the developed world has led to a broad-based economic slowdown in Asia and the Pacific, lowering economic growth forecasts.
The impact of slowdown will challenge regional inclusive and sustainable development with job growth and household income predicted to decline. UNESCAP estimates that, by 2013, 14 million fewer people in the Asia and Pacific region would be able to escape poverty at the $2-a-day poverty line.
In the Asia-Pacific region, almost two billion people are dependent on the traditional use of biomass and close to 700 million have no access to electricity. Among the various prevalent options, grid-based electrification has so far been the most widely used option, with renewable energy options accounting for a very small proportion. In the cooking and heating sectors, especially among rural households, biomass accounts for more than 30 per cent of total energy consumption in many developing countries, and in some Asia-Pacific countries its share stands as high as 95 per cent.
This paper argues that, with the removal of international sanctions and the opening up of the economy, fostering economic activity and facilitating investment in new and more productive industries will best facilitate inclusive economic growth in Myanmar. With a perspective that emphasizes the role of structural transformation, this paper presents a model describing how this can best be facilitated with the use of strategies that push towards diversification, particularly in the direction of more productive economic activities.
Agriculture remains the backbone of most Asia-Pacific developing economies and approximately 50% of the Asian working population is employed in the agricultural sector. In view of the export potential of agricultural products in the region, it is urgent to reduce trade costs in this sector, particularly since they are typically twice as high as those for manufactured goods. Agricultural trade costs within each of the different Asian subregions and country groups are not found to differ sharply, particularly when tariff costs are excluded.
Governments of the ESCAP region gathered in Incheon, Republic of Korea, from 29 October to 2 November 2012 to chart the course of the new Asian and Pacific Decade of Persons with Disabilities for the period 2013 to 2022. They were joined by representatives of civil society organizations, including organizations of and for persons with disabilities. Also in attendance were representatives of intergovernmental organizations, development cooperation agencies and the United Nations system.
Gender and Development Discussion Paper Series No. 21
Harmful Traditional Practices in Three Countries of South Asia: culture, human rights and violence against women.
The Disability at a Glance series, which started in 2006, serves as a companion for policymakers, statisticians and representatives of organizations of, and for, persons with disabilities in Asia and the Pacific. These publications aim to provide a regional overview of disability policies and practices, as well as relevant country data and information.
This publication on Disability, Livelihood and Poverty in Asia and the Pacific is an executive summary that draws from a wider body of primary and secondary research undertaken by the ESCAP research team. It considers both the quantitative and qualitative dimensions which shape the livelihood experiences of persons with disabilities. The primary research is derived from collaboration between ESCAP and its national research partners: disabled people's organizations (DPOs) and organizations for the empowerment of persons with disabilities.
This Guide covers the wide-ranging legal issues that are related to the development and operation of a Single Window and, to a certain degree, some of the important electronic commerce legal concepts and approaches applicable to the single window environment. It is intended to give policymakers a broad understanding of the key considerations that should be addressed in effectively establishing the legal infrastructure for a SW.
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