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Saving TV advertising the TiVo way
July 23, 2008 - 09:30
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Nintendo sorry for lackluster E3, hardcore 'misunderstanding'
July 23, 2008 - 09:29
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Microsoft Games for Windows LIVE multiplayer features now free
July 22, 2008 - 13:46
Theo Valich
Microsoft is hosting its XNA Gamefest conference in Seattle, and first news is coming in. Prepare yourself, it's big. First of all, starting with today, all Games for Windows - LIVE multiplayer services are completely free. Achievements, TruSkill matchaking, cross-platform play with Xbox 360 (on cross-platform games, such as Champions Online) - all of the features that went with GfW – LIVE Gold service became free. This is a logical move, since users of PC platform pay for operating system, while owners of Xbox and Xbox 360 consoles get their operating system for free (well not exactly free, but it's integrated into the price).
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Sony gets more aggressive, sets 150 million unit target for PS3
July 22, 2008 - 12:00
Wolfgang Gruener
After a very rocky start, Sony is now much more optimistic about the sales potential of its game console: Sony hopes the PS3 will outsell the PS2 eventually.
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The best thing we saw at E3 – D-BOX's rocking chair on steroids
July 21, 2008 - 18:51
Theo Valich
Most of E3 was pretty ho hum, but D-BOX, a small company from Quebec, showed us what can only be described as "rocking chairs on stereoids". D-BOX is not the first company to offer interactive racing or flying seats, but products we tested offered quite a compelling experience.
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Blast from the past: Apogee announces Duke Nukem trilogy
July 21, 2008 - 13:01
Theo Valich
Legendary software publisher, Apogee, is coming back from the grave with a vengeance. Apogee owns or co-owns a lot of heroes from the 1980s and 1990s and the company now looks to develop new versions or remakes of titles from the dawn of gaming and the first one will be Duke Nukem Trilogy.
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Update: The Dark Knight shatters box office records
July 20, 2008 - 23:19
Wolfgang Gruener
Warner Bros. Pictures' The Dark Knight set several new box office records during its opening weekend: The latest Batman movie had the biggest opening day, the biggest opening weekend and drove overall Hollywood box office weekend sales of the top 12 titles above a quarter of a billion dollars for the first time.
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Dark Knight tickets selling for $100+ on eBay and Craigslist
July 18, 2008 - 13:24
Humphrey Cheung
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World of Warcraft adding achievements to woo bored players
July 17, 2008 - 15:16
Humphrey Cheung
While World of Warcraft is the biggest MMORPG on the market, many players are a bit tired of the traditional hack and slash grind. Furthermore, life at level 70 can be a bit boring at times – sure you can get money and gear, but there really isn't that much difference between having 5000 gold or 100,000 gold, especially when you already own everything else. Now Blizzard Entertainment has announced the addition of achievements to the upcoming Wrath of the Lich King Expansion.
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Sony and Amazon team up to deliver video everywhere
July 17, 2008 - 13:31
Christian Zibreg
As part of its "video everywhere" strategy, Sony plans to marry Internet-equipped Bravia HDTVs with Amazon's new video-on-demand service to fight off increasing pressure from set-top box vendors. It is another try to convince consumers of the benefits of video-on-demand (VoD). No matter how you look at it, VoD looks like a matter of time and the days of your local video store may be counted. Even the recently more and more visible video kiosks may be sailing into an uncertain future.
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ESA reveals An Inconvenient Truth about the gaming industry
July 17, 2008 - 13:03
Theo Valich
After listening for years that games are mostly played by teens, Entertainment Software Association came forward today and released their annual booklet of facts. The booklet titled "Essential Facts About the Computer and Video Game Industry in 2008" is 14 mind-numbing pages filled with facts about the US video game industry – and some of those facts are definite eye-openers.
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PicoPC offers Windows XP embedded in home theater setting
July 17, 2008 - 11:28
Nino Marchetti
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2K bringing back 1994's Colonization
July 16, 2008 - 16:06
Theo Valich
2K is bringing back a serious blast from the past, Colonization from 1994. Under the name Civilization IV: Colonization, the game will use the Civilization IV Gamebryo engine which means low hardware demands and a lot of strategic thinking. The game features several nations to colonize and manage, but the basic premise remains the same: pick your race, territory and begin to create a nation.
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PC and Xbox 360 players battle in new Take-Two MMO
July 16, 2008 - 15:34
Theo Valich
PC and Xbox 360 gamers have typically stayed on their respective platforms, but an upcoming MMO game from Take-Two Interactive promises to change all that. he future of entertainment lies in crossover titles that join gaming platforms together. If there was any doubt, take a look at latest title from developers of well-known City of Heroes/City of Villains MMO series.
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What Microsoft does not want you to know about Netflix streaming
July 16, 2008 - 14:29
Samantha Rose
Opinion – Earlier this week, Microsoft and Netflix announced that movie streaming will be coming to the Xbox 360. This could be a big deal. But if you are really interested in watching Netflix content on your Xbox, you don't have to wait and you don't have to pay twice. If you have an Xbox 360 and a Windows Vista PC, you have everything you need to stream Netflix movies already.
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World of Warcraft update adds addiction curbing alarms
July 16, 2008 - 13:47
Humphrey Cheung
World of Warcraft players now have some extra tools to help them put down their virtual crack pipes. Yesterday, an update to WoW added time displays and alarms that warn players when they have exceeded their allotted playing time. Unfortunately, or fortunately for truly addicted players, the alarms have no real consequences because they are a simple 'DING' sound and some optional text.
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Redmond, we have a problem: Sony just cut the price of the PS3
July 16, 2008 - 10:00
Wolfgang Gruener
The game console market is getting more interesting: Following Microsoft's time-limited price cut of the Xbox 360 Premium, Sony has announced an upgrade of its 40 GB console to 80 GB, which could be interpreted as a permanent price cut of the flagship 80 GB Playstation 3, despite the loss of PS2 compatibility. The decision between an Xbox 360 and a PS3 is now much less a question of cost, but a question of how much the Xbox' entertainment features or the PS3's Blu-ray drive are worth to you.
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Nintendo rocks the house at E3, touts console and handheld supremacy
July 15, 2008 - 14:28
Humphrey Cheung
Nintendo literally rocked the house at their E3 press conference with music, games and even some stuffy business apps for the DS handheld. In what has become a typical E3 scene, Nintendo President Satoru Iwata and legendary game designer Shigeru Miyamoto were treated as the demigods of the gaming industry by the audience at the Kodak Theater in Hollywood California. The pair, along with Nintendo of America's President and COO Reggie Fils-Aime, slammed home the message that Nintendo, the Wii and the DS aren't fads and they certainly have the marketing numbers to prove it.
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Netflix coming to your Xbox 360
July 14, 2008 - 15:25
Wolfgang Gruener
We have our doubts about Microsoft's Xbox 360 strategy, which, in our opinion, lacks focus. But we cannot deny that the company has just made a brilliant move. Top-level Xbox Live subscribers, who are also Netflix subscribers, will be able to stream Netflix content through the console with no additional cost. Well, at least sort of. Could the Xbox 360 become what the Windows Media Center PC should have been? Absolutely.
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Microsoft exec says Xbox 360 will outsell the PS3 - update
July 14, 2008 - 15:10
Humphrey Cheung
Microsoft says its Xbox 360 will eventually outsell both the PlayStation 3 globally. Speaking at its Xbox press conference at the E3 gaming conference, Microsoft's senior vice president of entertainment, Don Mattrick, said the Xbox 360 hardware was in "fantastic shape". He touted the consoles impressive installed base in the United States and made an interesting prediction.
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Toshiba introduces ultra-thin laptop line
Mirics develops CUDA-based television platform
Nvidia kicks off 2009 GPU conference
ARM confirms it's chatting to GlobalFoundries
Apple's new Macs better be cheap
Judge overturns Microsoft patent judgement
HP bangs together printers and PCs
End of O2 iPhone monopoly is good news for UK users
Cosmic rays increase as sun hits solar minimum
Tyrannosaurs 'killed by throat infection'
Bank forces suspension of Gmail user's account
Microsoft finally gets anti-malware right
AMD talks up graphics as Nvidia kicks off GPU conference
Google rides crest of a social network Wave
ARM changes name of the netbook game
Nvidia showcases next-generation Fermi GPU
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|Geek Peeks - Billeder fra vores mobiler
|Well my friend Sweet Jay took me to that video arcade in town, right, and they don't speak English there, so Jay got into a fight and he's all, "Hey quit hasslin' me cuz' I don't speak French" or whatever! And then the guy said something in Paris talk, and I'm like, "Just back off!" And they're all, "Get out!" And we're like, "Make me!" It was cool.
|-- Scott Evil (Austin Powers, International Man of Mystery)

subset: commoncrawl


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Scott Bauer/Associated Press
Scott Bauer/Associated Press
MIDDLETON, Wis. � Remember Roseanne Roseannadana? Or Emily Litella? Or Baba Wawa?
Younger generations might not recognize the characters popularized by comedienne Gilda Radner. Nor might they remember Radner herself, an original cast member of �Saturday Night Live� who died 23 years ago and for whom a national cancer support group is named.
That�s troubling to the Madison-area chapter of Gilda�s Club, which planned last week to change its name in part because of concern that many don�t know who Radner was. The move prompted outrage from some Radner fans, who see it as a slight to a woman who confronted cancer with dignity and humor, and led other chapters across the nation to hastily reaffirm they have absolutely no intention of changing their names.
Lannia Syren Stenz, the Madison-area club�s executive director, said her organization decided to change its name to Cancer Support Community Southwest Wisconsin after it realized that most college students were born after Radner died in 1989.
�We are seeing younger and younger adults who are dealing with a cancer diagnosis,� Stenz told the Wisconsin State Journal. �We want to make sure that what we are is clear to them and that there�s not a lot of confusion that would cause people not to come in our doors.�
Her comments angered some Radner fans, who let loose a storm of criticism on the organization�s Facebook page.
�The only educating you�re doing is teaching kids that when they die from cancer, their name will be erased from history in 20 years because the next generation doesn�t know who they are. Way to give them hope!� wrote Mark Warneke, 44, a full-time college student in Arlington, Texas. He told the AP that taking Radner�s name off the foundation was an insult to her memory.
Stenz referred questions from The Associated Press to Linda House, executive vice president of the national group. House said there was no evidence that young people are unfamiliar with Radner, and the name change was motivated by the desire to make the organization�s mission clear. She called Stenz�s comments �not accurate, period.�
�Gilda Radner is very much a part of the fiber of this organization,� House said. �There has never been an intent and there is no intent to lose Gilda as part of the organization.�
Radner, who was diagnosed with ovarian cancer in 1986, sought support from The Wellness Community in California and wrote about her experience in her book It�s Always Something, a reference to one of her characters� catch-phrases.
Her friends and family started Gilda�s Club in 1991 on the East Coast to honor her legacy. The name was inspired by something Radner said after her diagnosis: �Having cancer gave me membership in an elite club I�d rather not belong to.�
Gilda�s Club Worldwide merged with The Wellness Community in 2009, and the joint headquarters in Washington changed its name to the Cancer Support Community. Local chapters were given the choice of keeping their names or switching to Cancer Support Community, House said.
The 56 chapters around the world deliver $40 million a year in free care to about 1 million cancer patients and their families, she said. Of those chapters, 20 are known as Gilda�s Club, three are Wellness Community and 23 are Cancer Support Community.
Changing the chapters� names made sense to Ron Nief, a professor at Beloit College in southern Wisconsin who has made a career out of studying how different generations view the world differently. He said it could become harder for Gilda�s Club to attract donations as fewer people remember seeing Radner on TV.
�I think we all want to keep our traditions alive,� he said, �but there comes a reality in this case of what does this group represent and how do we raise money for it.�
Radner�s husband, actor Gene Wilder, said he didn�t like the name change, but he understood it.
He said if he had to break the news to his late wife she might ask, �Do they have to throw me out?�
�I�d say, �It�s not throwing you out, honey, it�s getting more money.� And she�d say, �OK, I guess if they have to, they have to,�� he said. �It�s too bad. I wish it weren�t so. But I understand.�
The Wellness Center where Radner once sought support in Los Angeles was one of the groups that updated its name. Julia Forth, the marketing director of what�s now called the Cancer Support Community Benjamin Center, said people who get sick Google the word cancer, so it helps to have that word in the name.
Other organizations were adamant about keeping the Gilda�s Club name. LauraJane Hyde, who runs the Chicago chapter, said her group has spent 15 years teaching people that Radner�s name was synonymous with cancer support, in the same way people know what Starbucks sells even though �coffee� isn�t in its name.
�A lot of people feel very passionately about the name,� she said. �We will lose donations if we change it.�
Radner remains a strong presence at the Madison-area club even without her name on the building in the suburb of Middleton. Paintings and drawings of Radner line the walls. One depicts her on top of Madison�s state Capitol. Another imagines her sitting along the shores of Lake Mendota on the University of Wisconsin-Madison campus.
The meeting rooms are named after her Saturday Night Live characters, including New York street-smart reporter Roseanne Roseannadana, out-of-sync editorialist Emily Litella and speech-impeded talk show host Baba Wawa, a parody of Barbara Walters.


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Regional conference offers dairy producers guidance
Regional conference offers dairy producers guidance
Southern dairy producers can join those from across the region at a January conference in Atlanta addressing some of the major issues currently facing the industry.
Stephanie Hill Ward, assistant professor in animal and dairy science at Mississippi State University, is chairing the Southern Dairy Conference planning committee. She said the objective of the Jan. 24-25 conference is to offer informative and thought provoking presentations on all facets of the dairy industry.
"The conference will address production, processing and manufacturing. Topics include policy and legislation, milk prices, animal well-being, risk management, farm ownership and the next generation of dairy farmers," Ward said.
The conference will be held at the Embassy Suites near the Atlanta airport. Lodging reservations must be made directly with the hotel with a Southern Dairy Conference rate of $120 per night. Reservations can be made by contacting (800) 362-2779 or (404) 767-1988.
Registration for the conference before Jan. 11 is $125 for students and $200 for others. Late registrations are $250. Online registration is available at http://www.areg.caes.uga.edu. More conference information can be found at http://www.southerndairyconference.com or click to download the registration form here.
The conference is sponsored by the Southern Extension and Research Activity 15 regional committee (SERA15). The conference is planned by the Southern land-grant universities: Auburn, Clemson, Florida, Georgia, Kentucky, Louisiana State, Mississippi State, Missouri, North Carolina State, Texas A&M and Virginia Tech.
Topics and Speakers
- The Road Ahead for the Dairy Industry: Challenges and Opportunities, Scott Brown of the University of Missouri;
- Economic Effect of Dairy Security Act of 2011, Scott Brown of the University of Missouri;
- The Southeast and Dairy Policy, Calvin Covington, retired Dairy Breed and Cooperative Executive;
- Factors Impacting Farm Milk Price, retired Dairy Breed and Cooperative Executive;
- DFA Perspective on Dairy Future, Rick Smith of Dairy Farmers of America;
- Experiences in Teaching Dairy Risk Management using the FACTsim Market Simulation, John Van Sickle of the University of Florida;
- SUDIA Update, Cheryl Hayn, SUDIA general manager;
- Enhancing Dairy's Image by Building Consumer Trust, Mollie Waller with Strategic Business Relations Dairy Management Inc.;
- Improving Animal Well-Being through Facilities Management, Peter Krawczel of the University of Tennessee;
- North Carolina Dairy Advantage: Growing N.C.'s Dairy Industry, Shannon Davidson of N.C. Dairy Advantage;
- Training the Next Generation of the Dairy Industry, Cathy Williams of Louisiana State University;
- The Grazing Dairy Model: Providing a Viable and Exciting Business Opportunity for Young and Old, Tony Finch of Grasslands Dairies, LLC;
- Transition of Farm Ownership, David Marrison of Ohio State University Extension;
- Young Farmer Panel Discussion; Jeff Cornwell of North Carolina, Denise and Curtis Jones of Kentucky, and a Grassland Dairies Producer from Missouri.


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3 Kinds of People the Internet Accidentally Invented
#1. Artists in Bizarrely Specific Genres of Music
YouTube has been pretty great when I'm looking around for new and interesting music. Anyone, from anywhere, can upload absolutely any piece of music they want. I've found awesome music I likely never would have found had it not been for the Internet.
I've also noticed some weird, bizarrely specific musical trends thanks to YouTube. For example, based on the sheer amount of videos on YouTube that are just covers of the Super Mario Bros. theme played on different instruments, one would assume that you legally have to upload a Mario Bros. cover if you want to have an account on YouTube.
It's all there. The Super Mario Bros. theme on piano. Or bass. Or drums. Or gypsy-jazz style (whatever that means). Or one by a guy who plays the theme on flute while beatboxing AT THE SAME TIME. What were all of these people doing before YouTube?
Still, the fact that there are more covers of the Super Mario Bros. theme than I ever care to count isn't my favorite hyper-narrow music trend from the Internet. Every other word in this sentence links to a different cute girl with a ukulele performing a cover of some random, popular song. (Also, there's this delightful lady, who actually wrote a song making fun of this bizarre trend, appropriately titled "Cute Girl With a Ukulele.") Covers of rap songs, rock songs, whatever. Everything. And it's happening all over the world. Some of these people can't even speak English, but you better believe they know how to sing and play "We Are Young" on ukulele.
I'm not saying there's anything wrong with this -- hell, if YouTube hadn't invented the Cute Girl With Bangs Who Plays Hip-Hop on a Ukulele, I never would have known how totally into that I am -- I'm just confused. I studied music in college, and I can't say I remember meeting a lot of uke-trained women who wanted to show me their rad cover of the theme from Fresh Prince of Bel-Air. (Mostly, the women played flute, and the thing they wanted to show me was, like ... flute stuff, I guess.)
It's just one of those things that flourished on the Internet, and as far as I can tell, absolutely nowhere else. When the first webcam was invented, some woman with a ukulele decided to stare directly at the camera and record herself playing a random song, and then every woman between the ages of 14 and 23 decided to join her, and that's why, when the sun explodes and we all die and the aliens come to take a look at all of our historical records, they're going to assume that humanity was like 80 percent big-eyed cute chicks who played ukulele versions of pop songs.
Daniel O'Brien is Cracked.com's senior writer (ladies) and is into bangs and ukeleles (ladies ... again).
For more from Dan, check out Hey, Let's Fix The Internet and 4 Fashion Tips For Being Left Alone This Summer.


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Serves 6 |
Prep Time 5 minutes |
Cook Time 0 minutes
1/4 cup Eden Extra Virgin Olive Oil
1/4 cup cold water
2 tsp Eden Yellow Mustard
1 Tbsp Eden Red Wine Vinegar
2 pinches Eden Sea Salt
2 cloves garlic, minced
2 Tbsp scallions, chopped
1/4 cup fresh parsley, minced
1 tsp organic maple syrup
Place all ingredients except the parsley in a blender and pulse several seconds. Add the parsley, mix and place in a serving container. Keep refrigerated for 3 to 4 days.
American, Condiments, Gluten-Free, Italian, Low Sodium, Macrobiotic, No Sweetener Added, Oils, Salad Dressing & Marinade, Vegan, Vinegars, Wheat-Free


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on October 7, 2012 - 5:50 PM
Kim Grande did not hesitate when she was asked what compelled her to stand out in the rain Sunday afternoon and take part in a "Life Chain" of people protesting abortions.
"To me, the right to life is the most important issue facing America today," said Grande, 49, a mother of seven from Wheatfield. "If we don't value the lives of babies and old people, and people with disabilities, I think everything else goes down the tubes."
Grande, a member of St. Amelia's Catholic Church in the Town of Tonawanda, spent an hour at the intersection of Niagara Falls Boulevard and Glenalby Road in the town. She was accompanied by her husband Paul, their sons and daughters – ranging in age from 8 to 17 – and about 70 other members of her parish.
According to the Catholic Diocese of Buffalo, about 2,250 people joined the demonstration, carrying signs including "Save The Babies," "Abortion Kills A Child" and "Adoption, Not Abortion." The people lining Niagara Falls Boulevard stretched from Main Street in Buffalo to a location on Packard Road, 19 miles away in Niagara Falls.
The aim of the annual event is to form "a quiet, prayerful life chain," rather than engaging in loud and angry protests, said Cheryl Calire, director of pro-life activities for the diocese.
"I was thrilled to see so many people engaging in a prayerful, peaceful way, standing up for life," Calire said. "This is a non-confrontational event. We just try to get people to think about this very important issue for a few minutes."
Abortion has been legal in the United States since 1973, when the Supreme Court issued the landmark Roe vs. Wade decision, giving women the right to choice.
Polls show that many Americans do not agree with the Catholic Church's position that abortion is wrong in every circumstance and should be totally illegal.
In a nationwide Gallop poll taken earlier this year, 25 percent of people said abortion should be legal in all circumstances. Fifty-two percent said it should only be legal in certain circumstances.
Twenty percent said it should be illegal in all circumstances, and three percent said they had no opinion.
Although the issue of legalized abortion is important to millions of Americans, Grande and Polly Laudan, another demonstrator from the same parish, said they are surprised and disappointed at how little has been said about abortion during the current, heated campaign for president.
Laudan said she believes "the mainstream media" intentionally downplays the controversy.
Grande said she thinks the issue is a difficult one for many people, including those in politics and the media, because "it is so polarizing."
"I think there are a lot of people in this country who have mixed feelings about it. They have decided to be undecided about the issue," Grande said.
Both Grande and Laudan said they are convinced that Republican candidate Mitt Romney will do more to prevent abortions than the incumbent president, Barack Obama.
Obama has repeatedly gone on record as strongly pro-choice. He has said a woman's right to choose abortion is a "fundamental constitutional right."
Romney, for many years, said he supported a woman's right to choice, but during the current campaign, he has stated that he is strongly opposed to abortion, except in cases of incest or rape.
As he stood in the rain on Sunday, Monsignor Thomas F. Maloney, the pastor of St. Amelia's, said he hopes there will be plenty of discussion about abortion as the national campaign enters its final weeks.
"A woman's right to choose, and her baby's right to live – that's an important issue. That is something that ought to be discussed a lot," Maloney said. "To me, the right to life is the first, inalienable right for every person. That's why I am out here today."
As part of the diocese's "Respect Life Sunday," the region's new bishop, Bishop Richard J. Malone, led a mass for 500 people at St. Joseph Cathedral in downtown Buffalo. A large rosary, made up of helium-filled balloons, was released into the morning sky after the service.
email: firstname.lastname@example.com


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A place were they keep your change and give you a sandwich with two pieces of meat and whole lot of bread. Better off getting a sandwich at Harris Teeter. Jimmy johns janked me with a shitty sandwich.
jimmy johns is jank and the ganker behind the register kept my change. Stay away from the jimmy johns jankers in RTP, NC.
viết bởi pk to 07 Tháng năm, 2008


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Welcome to the UW-Manitowoc library!
Our goal is to help you succeed in college.
How can we help?
By providing access to information resources and professional assistance in finding and using them. We hope that the library will be your first choice for study, research, reading, and collaborative academic work with other students.
Contact Us
You can ask in person, via email or telephone, or by using the library chat service. We've got comfortable seating, technology, books, magazines, dvds, cds and a gorgeous view of Lake Michigan. If you don't find what you need, let us know, and we will find it for you. Please browse through this website to learn more about the UW-Manitowoc library.


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0 Members and 1 Lonely Barbarian are spying on this topic.
Whedon. That is all I need.
There are the two eggheads and their names are unimportant because they are functionally siamese twins and you dont see them without them sharing spilling over each other's dialog.Then there is tough guyAnd there is Asian pilot lady/driver person.
Page created in 0.153 seconds with 26 queries.


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The Stetson University women's soccer program will host an Identification Camp for current high school aged players looking for an opportunity to experience a Division I training environment.
The camp is scheduled for Saturday, February 9, 2013, and will be held on the fields next to the brand new Stetson University Athletics Training Center.
Players will be evaluated by the Stetson coaching staff. The camp curriculum provides more than four hours of training, as well as classroom sessions to discuss the recruiting process and NCAA eligibility requirements.
The camp is intended for players with a high level of interest in playing at the NCAA Division I level and Stetson University.
During the clinic players will have the opportunity to tour the new Athletics Training Center and play on the brand new fields.
The camp schedule is as follows (subject to change).
- 9:00 a.m. - Registration and check-in at the soccer field
- 9:30 a.m. - Technical session
- 10:30 a.m. - Small-sided games
- 11:30 a.m. - Lunch provided for all participants
- 12:15 p.m. - College search seminar
- 1:30 p.m. - Tactical session
- 2:30 p.m. - 11 vs. 11 round-robin play
- 4:30 p.m. - Question and answer session
- 5:00 p.m. - Camp ends
Interested players can register online here.
For more information, contact Assistant Coach Stephanie Webb at 407-460-5567 or via email at firstname.lastname@example.com.
Stetson University camps and clinics are open to any and all entrants (limited only by number, age, grade level and/or gender).


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The 6 Types of Profile Pics and What They Mean
#3. The Hot Friend
Sometimes you get followed on Twitter or friended on Facebook by people you don't know. (And if you whore your links out online, it happens a lot more.) Who is this new person in your life? Well, if their profile pic is two people, you just don't know. 50-50 chance of guessing, right?
David Woolley/Photodisc/Getty Images
"Pssst. For the purposes of this photo we'll pretend one of us is much hotter, because it's apparently impossible to find a picture of two women in the Getty photo library who are not equally attractive. Pretend there are many open sores on my face behind my whispering hand."
Actually, no. This is simple. Which person owns the profile? The ugly one. Of course, it's the ugly one. It's always the ugly one. They're either hoping that some of the hotness travels to them by osmosis or even that you mistake them for the hot one. It's like a half-hearted, muted "Catfish" move. How do we know the hot one didn't post? Because she just wouldn't want to risk being mistaken for fatty.
Take-Away Message: I have a hot friend.
#2. The No-Show
Ah, the most perplexing of online personalities. Who is this person? What do they look like? What are they about? You just don't know. Your only clues are the picture they choose to show you which will often be from a sci-fi or fantasy world, such as Doctor Who.
The mere ability to post a Doctor Who pic, however, does not mean they have the abilities of a Time Lord, only that they like a great show.
It's hard to get a read on the person with a no-show profile pic, but here's a helpful, if somewhat limited, guide:
George Doyle/Stockbyte/Getty Images
Ugly satanist
Dick Luria/Photodisc/Getty Images
Ugly serial killer
Ugly person with a scat fetish
Take-Away Message: Well, the instant assumption is that this is either an unsightly person or at the very least a person who believes they are unsightly, which is a bit more depressing. It is important to note that the person could be some high-ranking military official or celebrity preserving their anonymity, but I don't have anything funny to say about that.
#1. The 'Amram'
Unless, you suffer the same mental illness that I do, right now you're thinking "what is an Amram?" Well, according to my deficient mind, an "Amram" is a deliberately ugly profile pic. Y'know, making a funny, unattractive face. That's probably because I follow the delightful Megan Amram on Twitter whose pic looks like this:
Now, a normal person would have said, "Oh, look, this person named Megan Amram is making a silly face." But I just assumed Amram was hip Internet lingo. (She's in L.A. and has many more followers than I, so I just assumed I was out of the loop.) It didn't help that a friend of mine also used the term "Amram" in conversation -- because apparently mental illness is contagious.
Anyway, what can we say about people who make deliberately ugly faces in profile pics? Shockingly nothing. Beautiful people make ugly faces because they can get away with it. Ugly people make ugly faces because then they look ugly just like an attractive person making an ugly face. Also, people who are neither ugly nor beautiful also make ugly faces sometimes to be funny and sometimes because they feel they're not beautiful enough and haven't mastered the three-fourths turn addressed earlier.
Take-Away Message: I don't really have one. But I think it would be great if we all started calling deliberately ugly photos "Amrams," because then I wouldn't be alone in my stupidity. And if the Internet is good for one thing, it is sharing and spreading ignorance.
Watch the new HATE BY NUMBERS, where Will.i.am of the Black Eyed Peas recruits Britney Spears to make even worse music.
Also, be sure to follow Gladstone on Twitter and stay up-to-date on the latest regarding Notes from the Internet Apocalypse. And then there's his website and Tumblr, too.


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1) Do you have any money? (Used in BrE and AmE.)
2) Have you got any money? (Rarely used in AmE though very common in BrE.)
3) Have you any money? (Grammatical, though this construction is rarely used nowadays.)
I'm doing this pre-Delta task and one of the question is as follows:
2. Certainly. Here's our brochure. You can take away it.
a) Underline the errors
b) Write the corrections
c) Give a possible reason for the errors
Now obviously it should read You can take it away. But can someone explain the rule behind that or at least point me in the right direction? That'd be much much appreciated.
Thanks a lot.
Edit: I've got another example and I'd be grateful if you could have a quick look to see whether my explanation is ok:
- Do you have got any money?
b) Have you got any money?
c) This error is probably due to the fact that learners are taught they need an auxiliary such as do, am or have in order to form a question. There are essentially two ways to form this question:
1. Have you got any money?
2. Do you have any money?
Both options are grammatically correct but some regions prefer one version over the other. In this example, the learner obviously confused and mixed up the two versions.
Last edited by ametisto; 30-Dec-2012 at 11:39. Reason: addition
1) Do you have any money? (Used in BrE and AmE.)
2) Have you got any money? (Rarely used in AmE though very common in BrE.)
3) Have you any money? (Grammatical, though this construction is rarely used nowadays.)
I can understand learner's confusion these days with your second example. Teaching people the verb "to have got" instead of "to have" leads to such problems when trying to construct the negative or the interrogative.
The verb "to have got" had started to be taught in Spain while I was there and caused much confusion. I ended up teaching my students the two different versions and that they would just have to memorise them.
I have a car.
I do not have a car.
I don't have a car.
Do you have a car?
I have got a car.
I have not got a car.
I haven't got a car.
Have you got a car?
Remember - if you don't use correct capitalisation, punctuation and spacing, anything you write will be incorrect.


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|Albums > KruffleVapen > Pistols > Luger
|Hi! It's a huge album. If you have dial-up, don't wait on the thumbs to load - go to the folders! A couple of caveats: It's all legal where I reside, federal, state, and local. That may not be true where you live! All photos are copyright me, 2001-2005. You can download them, but don't publish them without permission.


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What makes men MEN! may just make us long-living men. Testosterone seems to be linked with longevity. That, according to this study led by a professor of clinical gerontology at the University of Cambridge School of Clinical Medicine. The study, led by Dr. Kay-Tee Khaw, warns that you shouldn't think it's a license for testosterone supplementation.


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Eligible participants: Faculty and students who have participated in Service Learning at UTB and TSC are invited to present their work. This is a cross- disciplinary exhibit and presentations are welcome in any area involved in service learning. The exhibit is an excellent forum for faculty to share their service learning projects with the university community and for students to develop their presentation skills.
Format: On the day of the exhibit, the authors will present their service learning project to groups or individuals through a poster presentation, performance, pictures, displays or video.
Proposals: Authors are invited to submit a proposal through the online submission form by November 21, 2012 Completed proposals should include:
All abstracts will be reviewed and acceptance notification will be sent out by November 26, 2012.
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text: Sandra McCune and Anthony Coffield of Valley Bend announce the birth of a daughter, born at 10:50 p.m. Aug. 25, 2012, in Davis Memorial Hospital. The infant weighed 7 pounds, 11 ounces and has been named Kensley Shacora Coffield. Siblings include Destiny Coffield. Maternal grandparents are Kenneth and Karen McCune. Paternal grandparents are Fred Stubbs and Andrea Coffield. Great-grandparents are Clara Blankenship and Prudy Moss.


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WINSTON-SALEM, N.C. - Four Hatters won singles matches and two doubles pairs advanced to semifinal contests as the Stetson women's tennis team played in the first day of competition of the Wake Forest Invite on Friday.
"The team performed very well today, especially in doubles," Stetson Director of Tennis Pierre Pilote said. "Diana and Isabella played their best doubles of the fall season so far. The level of competition is quite high at this event, and the team is loving the challenge."
Senior Diana Bukajeva defeated Giulia Andreazza of ETSU 6-1, 6-1 in the B bracket on Friday. She advanced to take on Nell Gaigher of Campbell in the quarterfinals on Saturday.
Sophomore Eveline Lepinay topped Macy Vonderschmidt of Charlotte by a score of 6-3, 6-3 in the C bracket. She will next play Yasmin Franco of UNC Greensboro in quarterfinal action on Saturday.
Freshmen Carolina Meregalli and Brittany Hill also won their singles matches on Friday. The former won 6-2, 6-0 over Brigita Bercyte of Wake Forest in the E bracket, while the latter topped Monica Aguado of Winthrop 6-3, 6-3 in the F bracket.
Bukajeva teamed with freshman Isabella Fernandez in doubles A bracket. The duo won 8-4 against Vonderschmidt/Grosellius of Charlotte, and then topped Choo/Gerbasi of ETSU by a score of 8-5. The doubles pair will take on Gardiner/Zhang of Wake Forest in the semifinals.
Sophomore Andrea Crespo and senior MayaBlue Stauffer-MacDowell advanced to the semis of the B doubles bracket. They won 8-7(2) against Crouser/Stein of Davidson in the first round. They then defeated Galstruk/Gaudreault of Maryland 8-6 to advance to take on Andreazza/Brumit of ETSU on Saturday.
Meregalli and freshman Marta Gonzalez won 8-4 over Kanii/Kanii in round one of the C doubles bracket, but then dropped their round two match. The duo will play against Williams/Gitman of Richmond in the consolation bracket.


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MACON, Ga. – Freshman Amanda Spring made history on Wednesday, as she became the first Stetson cross country student-athlete to earn Runner of the Week honors from the Atlantic Sun Conference, as announced by the league office.
Spring earned the weekly accolades after placing 24th out of 165 runners at the USF Invitational this past weekend. She recorded a time of 18:29 on the five kilometer course, leading the Hatters for the second straight week.
Stetson continues the 2013 season this weekend at the University of Florida/Mountain Dew Invitational in Gainesville, Florida.


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Serves 5 |
Prep Time 25 minutes |
Cook Time 25 minutes
2 Tbsp Eden Extra Virgin Olive Oil
2 cloves garlic, minced
1 medium onion, chopped
1 cup Eden Maitake Mushrooms, soaked 20 minutes in 1 cup warm water
1 cup Eden Sliced Shiitake Mushrooms, soaked 5 minutes in 1 cup warm water
25 ounces Eden Spaghetti Sauce, 1 jaror Eden Spaghetti Sauce - No Salt
1 tsp dried basil
1 cup organic coarsely ground corn grits (polenta)
3 cups water
1 pinch Eden Sea Salt
To prepare the marinara, heat oil in a medium saucepan and sauté garlic and onions for 2 to 3 minutes. Remove the shiitake and maitake from the soaking water. Save the water for soup stock. Chop the maitake coarsely. Add the shiitake and maitake to the saucepan and sauté another 2 to 3 minutes. Add the spaghetti sauce and basil. Cover and simmer for 20 minutes or until the maitake are tender.
While the sauce is cooking, prepare the polenta by bringing the water and salt to a boil. Whisk in the polenta, stirring constantly until it thickens. Reduce the flame to low and simmer for 15 to 20 minutes. If using finely ground polenta, reduce the water by 1 cup and cook 10 minutes. When the polenta is done, place on individual serving plates and ladle the sauce over each serving.
Condiments, Gluten-Free, Good/High Fiber, Good/High Protein, Italian, Japanese Food, Main Course, Mediterranean, Oils, Vegan, Wheat-Free, Whole Grain


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Top 5 open source project management tools in 2014
Top 5 open source project management tools in 2014
Last year, Opensource.com covered some popular open source project management tools (ProjectLibre, ]project-open[, and OpenProject.) We found these articles to be valuable to our readers, so here we take a look forward at what we think 2014 holds for these open source project management tools.
This is by no means an exhaustive list, but each tool listed here has been deliberately selected based on a rich feature set.
Read our updated list: Top 11 project management tools for 2016.
In our interview with Marc O'Brien, co-founder of ProjectLibre, we featured a tool with support for task management, resource allocation, tracking, Gantt charts, and much more. ProjectLibre is a good alternative to a commercial software product like Microsoft Project.
In December 2013, ProjectLibre released version 1.5.8, and a full rewrite of the codebase towards an Open Services Gateway Initiative (OSGI) modular architecture is ongoing. This will allow connector modules for better integration with enterprise solutions such as Enterprise Resource Planning (ERP).
ProjectLibre is a Java based client tool. During their 2014 Q1 this year, they will release version 2.0. It is not clear yet when the SaaS version will become available.
ProjectLibre was awarded InfoWorld's "Best of Open Source" in 2013 and ranks in my personal top 3 favorite open source project management tools.
LibrePlan is a web based application, making project management available to not just the project manager, but the entire project team, and if necessary across organisations. LibrePlan is licensed under the AGPL. This is another full featured tool supporting resource allocation, Gantt charts, financials, and more. These features coupled with a web based application make LibrePlan a great collaboration platform.
LibrePlan ranks in my personal top 3 favorite open source project management tools because of its modern design and balanced user interface, as well as, good and complete documentation, built in reporting, and professional support.
View all of the features on this page.
I did not note any newly released features or version release dates for 2014.
"Team collaboration redesigned" is how we introduced our interview with Birthe Lindenthal, Chairperson of the OpenProject Foundation's Board of Directors.
OpenProject is released under the GNU General Public License Version 3 and runs on Ruby on Rails. I happen to agree with their tagline that this tool has "everything you need for collaboration" to support the entire project life cycle. There are two big features that deserve to be highlighted: OpenProject supports Accessibility and a Scrum plugin supporting Agile methods and Scrum teams.
OpenProject is currently working on a major upgrade ready for release during 2014 Q1. Version 3.0 will support Ruby 2.0 and Rails 3.2. See their full roadmap here.
OpenProject ranks in my personal top 3 favorite open source project management tools because of their user interface, documentation, and rich feature set.
In our interview with Frank Bergmann, founder of ]project-open[, he gave readers insight into what this tool, ]po[ for short, is meant to do:
"We're not dealing with individual project managers, but focus on organizations with 10 - 1,000 users that earn their money by executing projects."
]po[ is said to be used by over 6,000 companies worldwide. A full installation is based on over 100 open source packages including a Linux distro, Postgre SQL, TCL as it's main language, Perl for system integration, and many more. It supports integration with 30+ packages such as OpenLDAP, OpenOffice, ProjectLibre, and others.
]po[ is an enterprise project management tool with many features, including support for Agile. The software is released under a mixed source model, or a "dual license", meaning that at it's core it is open source, with additional modules released under a commercial license. ]po[ runs as client software on both Windows and Linux, depending on a stack of open source packages.
In 2014, ]po[ hopes to release version 4.2 which will bring a full AJAX GUI, integration between collaboration features and project management, and more.
Redmine is a web-based project management tool that I actively use. It's powerful, runs on Ruby and Rails, and is licensed under GNU General Public License v2 (GPL).
Where it lacks enterprise features, compared with the other project management tools I've mentioned above, it has strong web applications. Along with basic project management features, this Redmine includes a wiki, repository, and issue tracker. View the full feature list here.
Redmine also has an advantage in access: it is available to project managers, other team members, as well as, the clients.
In 2014, the Redmine roadmap shows a steady flow of releases that continue to improve the quality of the tool.
BONUS TOOL: Agilefant
Agilefant, as its name implies, is based on Agile methods. However, this open source project management tool also supports product portfolios, projects, sprints, and multi-team development. See the full feature set in the Agilefant user guide.
Agilefant offers a free and open source product that can be downloaded and deployed into your own private cloud. They also offer a SaaS solution. In 2014, they will add a paid service.
Agilefant runs on Java, Tomcat, and MySQL. The source code and license can be found on GitHub.
Read our updated list: Top 5 open source project management tools in 2015.
64 Comments
Thanks for the review it's interesting to read. We use Dooster (Dooster.net) collaborative software and it also makes project management available to the whole team not just the project manager and also is for teams from 10 upwards. I know there's a daunting amount of packages to choose from and would like to say that Dooster is one that has made life easier for us.
Dooster is not OSS. It's not even free. That said, it looked like a fairly decent product, but the OSS tools on this list are just as good, if not better.
I agree. I don't know why people are posting closed source here. Suspect they are self-promoting!
I'd like to complete this list with top 5 from SourceForge (reference on opensource).
1) ]project-open[ : see above
2) ProjectLibre : see above
3) Ganib : very beautifull, well thought : worth to try
4) ProjeQtOr : not the most beautiful but one of the most complete and most intuitive and easy to extend (PHP) : my favorite ;)
5) FengOffice : seem to have limited functionalities, but well thought : worth to try
Ganib is the one that fulfilled our need of managing teams spread across three countries. Ganib.. Free and easy to use for everyone.
That is just all time downloads and not a real indication I think since some are very old and many can be downloaded from their own sites plus hosting auto installs.
Which of these have Team member access? such as Effort tracking and status update by team members.
I would like efforts expended to each task be classified against a Life Cycle activity (Design, Implementation, Testing, Reviews etc.,) is this possible with any of them?
Very nice and concise list, interesting to check out tools I didn't know about. We use Tracker (tracker.pm), however, and are pretty happy with its functionality (also the good thing is that the UI is under reconstruction J). It allows not only collaboration amongst the project-specific team, but also clients can see all the activity, track the progress and get involved in a discussion at any point. Works for us and clients love its simplicity, so perhaps we'll stick with Tracker for now :)
Thanks for the list! We are actually using teamwork in my company (http://www.twproject.com/) that is not open source but they provide complete sources to all customers, so if you are developers like us, you can access them and may add some functionality you need.
We are quite happy with it!
Another good OSS alternative that should be mentioned is http://www.web2project.net. Its a PHP based solution and very easy to get up and running.
Thanks a lot for the informative idea about top 5 open source project management tools.
Keep more sharing...!!!!
Very informative and helpful article.
I would never included Redmine.
How about qdPM or more to the point qdPM Extended. Both open source and highly augmentatble as well as configurable.
Compared to the other others qdPM is the best option we've found.
You should also consider www.project.net who was on the Gartner 2013 Report MarketScope for IT Project and Portfolio Management Software Applications http://www.project.net/content/projectnet-gartner-2013-report They have both managed private and packaged installations you can install yourself and have been around for years.
How much does it cost?
The open source software is free and can be installed by anyone. project.net also offers hosted solutions with maintenance as well with per user per year pricing options.
Isn't it inactive project. Last version way back in 2011.
You are right about that Adam. I did some more research and found out that they are active & they provide trial account on request. The latest version seem to be 9.4.
You can request for trial from http://www.project.net/content/try-projectnet
David, that's strange. I saw comments on fb/linked.in that project.net is more expansive than M$ Project and project.net new versions no longer open source?
Their OS community is killed and terminated. Do they have opened open source forum in last few years.
I buy qdPM Extended. It was only USD $195 one off price and it is open source. I am finding it very good. They have free version too but I want to try extra version since so cheap.
Project.net has actually restarted their forum here http://www.project.net/forum . Where did you see those comments?
Nice list. My personal favorite is ProjectLibre. I'm using this product for a year now and I never want to use something else.
I think that is is basically gantt chart. Project management is more than gantt chart. but look like good gantt chart like MS Project
nice to see the different open source solutions out there. I have tried a few, took LibrePlan the furthest but in the end I needed something to manage resources plans too and not just the project details. I found Hub Planner http://hubplanner.com and although it is not open source I am happy testing it out.
Actually this looks like a Gantt chart too!
If you'd like a tool for managing your time and projects, you can use this web-application inspired by David Allen's GTD:
GTD Agenda.com
You can use it to manage your goals, projects and tasks, set next actions and contexts, use checklists, and a calendar.
Syncs with Evernote and Google Calendar, and also comes with mobile version, and Android and iPhone apps.
This is not open source either.
Very heartening to know that some open source tools are doing a great job in the field of project and task management. But users simply want good results from the tools they use whether they fit into open source category or into any other. We also use an online project management application named proofhub http://www.proofhub.com/ for managing our projects. Has got some really useful features like online discussions, mobile feature, timesheets, calendar and Gantt charts. Quite Pleased with results.
I like to look around so I looked at proofhub. IT is not open source at all. Plusis it just another expensive hosted solution.
I actually bought qdPM Extended that the other poster talked about. It was only 195 USD one off fee. proofhub would cost me $149 a month for same options.
Have a look at ProjeQtOr : it is real Open Source, fully operational (not a 10% Open Source, pay for full version), and not limited to Gantt.
Moreover, it covers features often forgotten by Project Management tools (even proprietary ones) : Risk Management Plan, Mettings, Testing, Requirements, Decisions, Questions, Quality CheckLists, ...
When i wen through the other sites i found, ClockingIT, OpenGoo, KForge, etc.
I would not call any of them project management solutions.
I've been using Integria IMS to administer my proyects at my company and is very useful for handling tickets and giving technical support to clients. It's an opensource program and so it's free. For more information you can visit the following webpage: http://integriaims.com/Integria/projectman/en
Ivo Yordanov
The free version of qdPM looks better than that option.
I tried ProjectLibre and at the start this looked good. But then I ran into an issue, where I am sure that this is a user error, so wanted to check out the documentation. Turns out that this is hidden behind a "you need to get a community account to see documentation" page.
If I can work around my issue I will continue using PL, otherwise just try the next tool and migrate my data. I do not want an account all over the place just to look at some docs
ProjectLibre is an "Open source replacement of Microsoft Project", so to summarize : a project planner.
I want to shout out loud ounce again that Project Management is NOT ONLY Planning.
ProjectLibre can be one of the tools to setup a Project Management platform, just like Mantis-BT can be, or Excel.
Please concider real Project Management tools.
I completely agree with you!
We're using qdPM Extended now as it meets all our needs.
We moved from Confluence + Jira because those tools are not PM tools ether just a fancy wiki + task tracking.
With qdPM Extended we can do all we need in terms of PM.
I've been happily using ProjectLibre since I read about it here. I find the tool very effective when it comes to project planning. Its fairly straight forward and just seems to work. Key is having a tool that doesn't make your job harder or more tedious and this one fits the bill.
Interesting article. I didn't know there was open source project management softwares. I use to use Beesy.me for online project management, but it is not open source. However almost everything can be configured and it is really powerful. You can find the web based solution here: www.beesy.me (which has different prices, from free to $15 a month with full options, however there is one month free trial) and there is the associated iPad app: http://www.beesapps.com/beesy-ipad-to-do/


text:
Expanding Use of NGS Has Largely...
As Immunotherapy Revolutionizes the Cancer Treatment...
Wall Street Decline Takes Its Toll...
LC-MS Gains Favor Due To the...
Resveratrol, a compound found in some red wines, reportedly triggers gene-expression patterns similar to those induced by caloric restriction, which extends life in animal models.
Just what did GlaxoSmithKline (GSK) get for its dime when, in 2008, it dropped $720 million (or 72 billion dimes) to buy Sirtris Pharmaceuticals? It gained small molecule antiaging drugs that work, according to Sirtris, by mimicking some of the beneficial effects of caloric restriction mediated by resveratrol, a compound found in some red wines.
Founded in 2004, Sirtris went public in May 2007 and continues as an independent discovery performance unit within GSK. The buyout was another giant coup for Sirtris founder and Boston biotech entrepreneur Christoph Westphal, M.D., Ph.D. He reportedly could earn up to $25 million from the deal as well as a $2 million bonus to stay on for four years to run Sirtris/GSK. All the investors involved also made a bunch of money. Dr. Westphal has consistently done well for his investors: He co-founded and was CEO of Alnylam Pharmaceuticals, Momenta Pharmaceuticals, as well as Acceleron Pharma and was also co-founder of Concert Pharmaceuticals.
GSK believes that it got a good deal, with Sirtris' drug candidates adding to GSK's metabolic-disease drug pipeline. The company said that the acquisition reflected its strategy of pursuing the best new science to bring novel medicines to patients and value to its pipeline. But two research papers recently called into question some basics of the new science underlying Sirtris' drug candidates. Such confounding results highlight the complexity of SIRT1 activation, the mechanism behind Sirtris' antiaging candidates.
Yay and Nays for SIRT1 Activation as an Antiaging Tool
A group of investigators at Amgen concluded that "the pharmacological effects of resveratrol in various models are unlikely to be mediated by a direct enhancement of the catalytic activity of the SIRT1 enzyme. In consequence, our data challenge the overall utility of resveratrol as a pharmacological tool to directly activate SIRT1."
Separately, Pfizer found in in vitro studies using synthetic and natural substrates that SRT1720, SRT2183, SRT1460, and resveratrol did not directly activate SIRT1; SRT1720, SRT2183, and SRT1460 were all identified by Sirtris as candidates at some point. The investigators also found that the compounds were highly promiscuous in their interaction. Additionally, their study of SRT1750's in vivo efficacy in high fat ob/ob mice did not find a decrease in plasma glucose at comparable dose levels to those used by Sirtris and discovered an increased food intake and weight gain in the treated mice. Higher doses of the drug intended to increase glucose tolerance resulted in three dead mice.
These findings directly contradict the work of David Sinclair, Ph.D., of Harvard Medical School and a Sirtris founding scientist. With regard to Pfizer's findings, Dr. Sinclair commented, "Purity of the compounds that were used in their study cannot be ascertained due to the lack of data provided. The publication also does not cite nor discuss multiple scientific publications that are in direct contrast to their primary conclusions. As such it is unclear how to place this work in perspective of what has been found by other investigators."
A large body of basic research does indeed support the nomination of SIRT1 activators as antiaging drugs. SIRT1 activation has profound metabolic effects: It regulates glucose or lipid metabolism through its deacetylase activity for over two dozen known substrates and has a positive role in the metabolic pathway through its direct or indirect involvement in insulin signaling. It also stimulates glucose-dependent insulin secretion from pancreatic β cells and directly stimulates insulin-signaling pathways in insulin-sensitive organs. SIRT1 also reportedly influences adiponectin secretion, inflammatory responses, gluconeogenesis, and levels of reactive oxygen species, which together contribute to the development of insulin resistance.
The importance of SIRT1 is evidenced by the fact that inactivation of SIRT1 has significant consequences: Inbred knockout mice lacking SIRT1 show developmental defects, have a low survival rate, and have a significantly shorter lifespan compared with wild-type mice.
Sirtris based its small molecule drug development programs on basic research conducted by Dr. Sinclair and Leonard Guarente, Ph.D., of MIT who showed that caloric restriction in animals, long known to extend life, is associated with SIRT1 activity. The company's mouse studies showed that resveratrol "induces gene-expression patterns in multiple tissues that parallel those induced by dietary restriction."
The study also found a significant increase in lifespan in both the resveratrol-treated group on a high-calorie diet and the resveratrol-treated group on a calorie-restriction diet. The treatments, however, did not extend lifespan in mice on a standard diet. The resveratrol-treated mice did show markers for improved cardiovascular health and reduced aortic stiffness, according to the company.
These findings, the company noted, support the idea that resveratrol can mimic many effects of dietary restriction in vivo. Sirtris said that it has developed thousands of small molecules with much greater potency than resveratrol, allowing administration in much smaller doses. Increasing SIRT1 activity, either by transgenic overexpression of the SIRT1 gene in mice or by pharmacological activation by small molecule activators like resveratrol and SRT1720, the synthetic resveratrol, reportedly delayed the onset and reduced the incidence of age-related diseases such as type 2 diabetes. Sirtris also reported that SRT1720 improved whole-body glucose homeostasis and insulin sensitivity in adipose tissue, skeletal muscle, and the liver.
Based on its research, Sirtris is forging ahead with its Sirtuin program with NCEs that are reportedly chemically distinct from and more potent in vivo than resveratrol. In January 2008, the company announced that its first product to enter the clinic, SRT501, was "found to be safe and well tolerated and to significantly lower glucose in an oral glucose-tolerance test conducted as part of a 28-day Phase Ib clinical study in patients with type 2 diabetes." In April 2008, the company said that the FDA granted resveratrol orphan drug designation as a treatment of MELAS syndrome (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes). Since then neither GSK nor Sirtris has put out a press release related to its Sirtuin program, but Jamie Morgan, spokesperson for GSK, told GEN that the firm plans a pipeline update shortly.
Nascent Field Is in Need of Validation
And the Sirtuin story will grow more and more complicated. In 2009, MIT's Dr. Guarente published a study in Genes and Development reporting that sirtuins bring about the effects of calorie restriction on a brain system known as the somatotropic signaling axis, which controls growth and influences lifespan length. "The new study," Dr. Sinclair commented, "fills in an important missing piece of the sirtuin puzzle—how sirtuins act in the brain to mediate the effects of calorie restriction. Until this paper, the focus has been on tissues like muscles and liver and other organs that control metabolism."
Richard Miller, professor of pathology at the University of Michigan Medical School Institute of Gerontology, pointed out, however, that Dr. Guarente's study did not link SIRT1 knockout with shorter lifespan or declining health. The relationship between sirtuins and longevity, he said, is "more complicated than people had hoped would be the case." He thinks that sirtuins are likely one of many cell-signaling systems that influence aging.
In an April 2008 interview with Forbes about why GSK acquired Sirtris, Patrick Vallance, head of drug discovery at GSK, said "Like a lot of areas of science, it's got its controversies, and like many biotechs in this stage with a good pathway, this hasn't been proven yet. It has to be proven with a medicine."
Patricia F. Dimond, Ph.D., is a principal at BioInsight Consulting. Email: [email protected].
Patricia F. Dimond, Ph.D., is a principal at BioInsight Consulting. Email: [email protected].
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While Zika continues to garner a lot of news coverage, a Mayo Clinic survey reveals that Americans believe the country's most significant healthcare challenge is cancer. Compared to other diseases, does the possibility of developing cancer worry you the most?
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text:
Wauwatosa Police investigated a bomb threat at a senior living center early Thursday.
Police said an alleged threat of a bomb in a bathroom was received at St. Camillus Senior Living, 10101 W. Wisconsin Ave.
Officers said employees received a series of suspicious calls around 7:30 a.m.
Staff members investigated and found nothing. Police were called and the Milwaukee County Sheriff's Office sent explosive-detecting dogs to the facility.
Residents from one building were evacuated to another building while the search was being performed.
Police said no bomb was found.


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(3BL Media and Just Means)-The Windy City is about to get windier. And hopefully, less reliant on fossil fuels. IKEA recently announced their purchase of Hoopeston Wind, a wind farm of 49 wind turbines near Hoopeston in Vermilion County, two hours south of Chicago. The purchase is the first wind power investment IKEA has made in the USA and their largest renewable energy project ever.


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Holiday office party etiquette
Published On: Dec 01 2011 08:52:41 PM CST Updated On: Dec 03 2013 12:00:00 AM CSTSorry, Flash is not supported.
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duckies are the cutest things in the whole wide world. Varieties are the rubber ducky, live ducky, quacky ducky, yellow ducky and so many more
Girl: I want to go out
Boy:no thanks, I am busy playing with my ducky
Boy:no thanks, I am busy playing with my ducky
av professional nargle stunner 15 augusti 2011
Trending Now
Can you define these popular missing words?
Top Definition
Meaning fine, OK, or allright.
Everything is ducky.
av Justin 6 januari 2004
Object that makes your bath time so much fun.
Person who does the above.
Person who does the above.
Rubber Ducky, Your the One,
You Make My Bath Time So Much Fun
Wanna Be My Ducky?
You Make My Bath Time So Much Fun
Wanna Be My Ducky?
av Bunny69 9 oktober 2005
Whatever you say, ducky.
av Minshue 9 oktober 2007
dolla bills, benjamins, washingtons, money
yo hoe you got any duckies for dinner tonight?
av mofo & little boo 19 oktober 2007
A cute character from the children's film The Land Before Time. She is small, green, swims, and has a big mouth.
"My name is Ducky. Yep, that is what ist is, yep yep yep!"
av Silverina 28 maj 2005
Breasts of women.
Duckies is old English slang for boobs. There are love letters from Henry the 8th to Anne Boleyn saying that he cannot wait to rest his head upon her fine fine duckies.
av captain503 17 juli 2013


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A Lancaster County man is jailed after he fired a gun during a custody dispute, according to police.
Samuel Myers, 26, fired several shots into a car that was parked in the 800 block of Church Street in East Hempfield Township Sunday, police said.
A man and a toddler were inside the car and a woman was standing outside the car when the shots were fired, but no one was hit, police said.
Myers went back into his home, but officers convinced him to surrender, police said.
He has been charged with aggravated assault, recklessly endangering another person and endangering the welfare of children.


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Tax Day freebies and discounts
POSTED: 06:15 AM MDT Apr 15, 2014
Find out which businesses and restaurants are offering free or discounted items on Tax Day.
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How do i do it?
Edit: arg sorry, thought this was the tech section, If a mod could kindly move this please.
Ask, and ye shall receive.
2 clients that you can run simeoustainly, preferable 2 screens and special software depending on what you want to do.
You Sir Are Wrong, And If You Are Not Wrong, You Sir, Are Still Wrong
Most of the solutions won't work because of Gameguard and such programs, since they'll only start once.
Possibly thing to do is install a virtual machine and play the game from there, haven't tried it out though.
whups thought it was WoW.
Wut game is this in the first place?
2 systems with two clients with two accounts and different ip addresses?
You Sir Are Wrong, And If You Are Not Wrong, You Sir, Are Still Wrong
The easiest way to dual-box is to have two computers. I think with wow you can just open up more instances of it. Whereas games with more protection tend to be harder to dual-box with without running a virtual machine on your computer.


text: This bistro is right opposite the Gantrisch and the Guggershörnli. Situated on the edge of the village, it is a trendy bar in a somewhat surprising style, with panoramic windows like you more often see in an urban setting. In this unusual new building, with a kitchen display and cookery studio, a very special restaurant has been created. There are lots of little delicacies to sample, Italian ice-cream and fine wines.


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Found 2 results
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Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia. Nature communications, 2014/10/31, Volume 5, p.5316, (2014) Read More / View Supplemental Materials Abstract
Strain-Specific Regulation of Striatal Phenotype in Drd2-eGFP BAC Transgenic Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012/07/04, Volume 32, Issue 27, p.9124-9132, (2012) Read More / View Supplemental Materials Abstract
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America's most literate cities
POSTED: 02:32 PM PST Jan 25, 2012 UPDATED: 12:52 PM PDT Sep 27, 2012
How much do people read in the nation's largest metro areas? Read more to find out if your city made the top 20.
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Ask The Mayor
Mayor Alan Arakawa answers some of the most-asked questions submitted to his office staff.
May 6, 2013
Q: Are all the lunch wagons along Maui roads doing business legally? I enjoy the variety and convenience of them, however my concern is regarding the safety of the food....
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Sources: Live Science, AGU Meeting Schedule
quote: As a popular YEC song explains, "If there really was a worldwide flood, what would the evidence be? Billions of dead things, buried in rock layers, laid down by water, all over the earth."
quote: But the interesting part is that [the levels of carbon in sedimentary layers] rose so quickly that he feels that the sedimentary analysis rules out change by slower-acting forms of carbon release, such as volcanoes.
quote: If he is correct it suggests that methanosarcina could be the most diabolical murderer in history,


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14 Bizarre Scenarios That Are Way Too Common in Stock Photos
Previously, I've done my best to explain the story behind some simply baffling stock photo genres. Now we enter round two, because stock photos will never stop being ridiculous and/or confusing.
... because the big merger is happening during the big fight.
... because I didn't know I'd be boxing today.
... because it's Friday and we have such a cool boss!
... because I knew I'd be boxing today.
... because it's any day of the week and I've sort of checked out at work lately.
... I don't know, because these binoculars made the very nearby thing look way too big.
... It's my computer! And I know that because I'm holding it, not because of these binoculars.
... My computer, and I only know that because of these binoculars. Thank God for these binoculars.
... Anything, thanks to the power of imagination! Cherish humanity's ability to imagine!
... because I forgot that one is supposed to take off one's pants and underpants before pooping.
... because this morning I ate my beloved childhood pet, so now I am pooping it out.
... because I was on the toilet, pooping, then I punched some glue, and then suddenly I became pensive. I have since finished pooping, and I can't use my hands for wiping because they're stuck to my face. How will I wipe the poop from my butt without the use of these hands of mine? Oh, bother.
... because it killed my family.
... and you should seek a second opinion.
... because I already took the time to catch it. Might as well do something, ya know?
... because I'm a bad doctor.
... because I'm a good doctor but a bad person.
... because I have your television pointer, human. Fear me, for I am speaking, yet I am many dogs.
... because I am a human in an unbelievably lifelike dog costume and, yes, I'm watching TV right now. I work all day, let me watch a fucking second of goddamn anything.
... because I'm the main character of 2015's Look Who's Talking on Other Channels. I'm played by Willem Dafoe, so hi, I'm Willem Dafoe, and I'm in this seriously unbelievably lifelike dog costume. Be sure to see me and a female cast member as Metch and Twong, two lazy dogs who are pretty dumb, even for dogs. One prefers wagging and the other prefers panting, and by the end we realize that neither of those things matters in the long run due to the futility of life, especially if you're a dog. Don't check it out if you get bummed easily. Definitely check it out if you want to see some seriously revolutionary costuming going on.
... because I'm just sitting here, waiting for Barking Bad to come back.


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to 03:00 PM
1200 N. D Street, Dean Hall, Central Washington University Campus
Ellensburg, WA 98926
Phone: 5099632313
Local fire history explored at new exhibit at CWU Museum of Culture and Environment
The Museum of Culture and Environment (MCE) at Central Washington University invites community members to come explore our new exhibition: Where There's Smoke... Living with Fire. Where There's Smoke explores how fire has influenced our lives, from the plant life that thrives after a burn, to the way humans fight fires, to the lasting impact that ancient and recent fires have on our modern life.
This exhibition was inspired by the 2012 wildland fire season and its impact on Ellensburg. The Taylor Bridge Fire, which became out of control in a matter of hours, consumed over 60 homes and 23,000 acres. It was followed by the Table Mountain Fire, which burned over 40,000 acres. In their aftermath, we are left with a set of questions about fire and the role it plays in our lives.
Where There's Smoke provides a glimpse into the long history of fire in Central Washington State. Explore clues left by fires that took place thousands of years ago and learn about the role that fire played in the lives of Native American communities. Delve into historical archives to assess how fire regimes change with the arrival of industrialization, agriculture, and urbanization. Engage with the powerful stories told by residents and firefighters who have experienced recent fires.
Visit the MCE between October 2nd, 2013 – March 22nd, 2014 to address your "burning questions" about the science of fire and its relationship to our culture and environment. The MCE is located in Dean Hall on the CWU campus, 1200 N. D Street. The Museum's hours are Wednesday through Friday 11:00 a.m. – 4:00 p.m. and Saturday from 10:00 a.m. to 3:00 p.m. Parking is free on the CWU campus after weekdays after 4:30 p.m. and on weekends. For more information, please contact firstname.lastname@example.com or call (509)-963-2313.


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From Nicki Minaj to Beyoncé, Jennifer Lopez to Jessica Biel, the star backsides take many different shapes and sizes.
Not surprisingly, this is the area my clients tend to focus on most. It's one part you really can't fake. Sure, you can wear those ridiculous padded underwear, but the truth is you're probably not fooling anyone but yourself – especially in a bikini.
A toned backside truly anchors your physique, and can make the difference between jeans fitting … and jeans REALLY fitting.
The key to toning your butt can be broken down into three muscle groups.
First, and most obviously, you need to train your gluteus muscles. The "glutes" enable us to extend at the hip and are active when your thighs moves away from the front of your upper body.
Great glute exercises1. Skater Lunge (see above)
2. Walking Lunge
Courtesy Harley Pasternak
3. Single Leg Squat
Courtesy Harley Pasternak
The second area to focus on is your hamstrings. The hams originate from your "butt bones" (ischial tuberosity), thus, tie in with the glute muscles. Working on the hamstrings and helps shape and tone the bottom of the butt.
Work your hams4. Stiff leg dead-lifts
Courtesy Harley Pasternak
5. Hamstring ball curl
Courtesy Harley Pasternak
The final muscle group to consider, is your lower back (spinal erectors). These muscles tie in to the top of your butt region and help us extend our back, otherwise know as "arching your back." Strengthening the lower back helps develop that sexy curve everyone wants from your back to your bum.
Back exercises6. Superman
Courtesy Harley Pasternak
7. Bridge
Courtesy Harley Pasternak
Adding in three sets of 20 reps each into your routine should do the trick.
Check back every Wednesday for more insider tips on Hollywood's hottest bodies – and learn how to get one yourself! Plus: follow Harley on Twitter at @harleypasternak.
RELATED: Seven Minutes of Exercise May Be All You Need
RELATED: How Alcohol Can Sabotage Your Goals
MORE: All Harley's Blogs and Training Advice


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Homegrown beetroot and chard (or leaf beet) seeds are simply delicious and easy to grow. They can generally be sown from March to July/August and will give you a good crop of vegetables to keep your salads bright and fresh.
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Beetroot 'Bolivar' (Globe) - Duchy Originals Organic Seeds
Beta vulgarisThe tender, globe shaped roots of Beetroot 'Bolivar' have beautifully smooth skins and a rich, deep red colour. This high yielding variety is ideal for harvesting as baby beets while young, or let them mature for a delicious full sized crop. Height: 30cm (12"). Spread: 15cm (6"). More info
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Even as some sort of routine is being reestablished in Newtown, Conn., after the horrific events of Dec. 14, help for those directly involved is being offered from far and wide.
Counseling services are available through Friday, according to the Newtown Public School District website. Those in need can also call 211.
"We are grateful for all the prayers, thoughts and outpouring of support offered to our community during this difficult time," reads the school district's message.
Those wishing to offer financial donations can make them to the Sandy Hook School Support Fund, which can be accessed here. (Checks also can be mailed to Sandy Hook School Support Fund, c/o Newtown Savings Bank, 39 Main St., Newtown, CT 06470.)
For now, the elementary school will remain closed, although students are due to return to class at the vacant Chalk Hill School, in nearby Monroe. "Welcome Sandy Hook Elementary," reads a sign across the street, according to news photos.
The family of Sandy Hook's beloved principal Dawn Hochsprung, who was killed Friday, is also organizing a scholarship fund in her honor to help a local high-school senior pursue a career in education, reports the community's Patch.
Hochsprung's daughter Erica Lafferty said the scholarship will be awarded to "a student who has a deep passion for inspiring the love and learning in children."
How to Help Those in Need After Shooting in Newtown


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on November 16, 2012 - 11:28 PM
, updated November 17, 2012 at 1:56 AM
Three Buffalo Police officers have been cleared of wrongdoing in two shooting cases – one resulting in the death of an ex-convict who was high on cocaine.
Erie County District Attorney Frank A. Sedita III said the grand jury findings were handed up earlier in the week.
Mark P. Andrzejak, 35, was cleared in the fatal shooting of parolee John A. Sordetto in the 400 block of Tonawanda Street about 5 a.m. May 27.
Karl B. Schultz, 26, and Jason R. Whitenight, 28, were cleared in the shooting of Wilson Morales, 17, at French and Moselle streets, about 3 a.m. June 24, following a high-speed car chase.
Thomas H. Burton, chief attorney for the Buffalo Police Benevolent Association, said Schultz and Whitenight testified before a grand jury two weeks ago and Andrzejak testified before a different grand jury on Wednesday. .
Sordetto, 25, a convicted burglar who had been kicked out of a Bailey Avenue halfway house for parolees a day before he was fatally shot, fought with Andrzejak, who had stopped him for questioning about the theft of a Buffalo police car about a half-hour earlier. As Andrzejak attempted to handcuff him, Sordetto punched him in the eye and tried to take his service pistol.
Andrzejak shot Sordetto before passing out. Sordetto died later in Erie County Medical Center. Sordetto, who was ultimately cleared in the stolen police car case, had been sent to the Buffalo halfway house in March after serving nearly three years for a Buffalo burglary.
Andrzejak, now back on duty with D District, was off for two months of medical leave, recuperating from head and eye injuries suffered in the confrontation with Sordetto.
Burton said Andrzejak fired at Sordetto "in a life-or-death struggle with a parolee high on cocaine and fortunately the officer came out on top."
Schultz and Whitenight both fired into the van driven by Morales, who was chased throughout the East Side. Morales attempted to back the van into Whitenight after crashing near the suspect's French Street home. Morales, who is still recuperating, faces trial on charges of assaulting a police officer and unlawfully fleeing from a police officer.
Burton said Whitenight fired in self-defense because he found himself "in every cop's nightmare, suddenly being on the receiving end of a vehicle with its engine roaring." He said Schultz fired into the vehicle "to protect his partner."
email: firstname.lastname@example.com


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quote: Apple will always be a temporary fad
quote: I thought IBM invented the personal computer.
quote: I've never purchased an Apple product and have no intention of doing so. Their business practices are at times anti-competitive and downright illegal.
quote: They are a bigoted company with an extremely self-absorbed, egotistical CEO. The price premium on their products is enough for me alone to look elsewhere.
quote: They treat their platform developers terribly, denying their good quality apps due to that developer being a competitor, and other illegitimate reasons.
quote: Their products are treated by the media like a cure for cancer. Sheeple queue in day-long lines to get their hands on their latest toy. Their consumer base is heavily stereotyped with a bigoted ignorance, of which stereotype PC users as "poor".
quote: Apple may have been around for over 3 decades, but in my world, they will always be a fad.
quote: Wikipedia isn't a great source to be using, just saying. Apple has never invented anything, that's just fact. Whether or not they made something popular is a completely different story.
quote: Ohhh, and IMO stuff you buy works as well as you treat it. Treat it like garbage and it'll be running/working like shit in no time flat.
quote: apple and tony sitting on a tree, k-i-s-s-i-n-g.. :P
quote: You are confusing Apple besting its competitors, with better products that consumers want more, with being anti-competitive.
quote: Do you really make buying decision on the basis of how a particular company's CEO is represented in the media? Sounds daft to me but it's your money and your life.
quote: If you want to look for cheaper products that's your right - in my experience generally you get what you pay for.
quote: Presumably that's why Apple the have the most developers and the most apps.
quote: Because you don't like Apple's products you cannot fathom why others do. So you can only explain it by people being misled on a vast scale and in order to explain that you have to argue that millions of people are acting stupidly and against their own best interests. This sort of explanation is comforting because (a) you can feel superior to all those stupid people and (b) it means you don't have to think about what Apple is doing right in order to attract all those millions of new customers.
quote: I can see the appeal of their products and have no issue with those that puchase them.
quote: Sheeple queue in day-long lines to get their hands on their latest toy.


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J.J. Henry has been wearing a hat embroidered with the letters "SHES," for Sandy Hook Elementary School, during the Hyundai Tournament of Champions.
Henry grew up in Fairfield, Conn., approximately 20 miles from the school where a shooting last month took the lives of 26 children and educators.
"At the first event of the year, I just wanted to do something to honor the families and lost ones," said Henry, who qualified for the field at the Kapalua Plantation Course for the second time by winning last year's Reno-Tahoe Open. "I just wanted them to know that the entire PGA Tour family, whether it's players, officials, media or fans, that we're all thinking about them in this unthinkable time."
Article Photos
J.J. Henry is interviewed by the Golf Channel's Tim Rosenfort outside the clubhouse on Saturday.
The Maui News / MATTHEW THAYER photo
Let's play two (rounds)
Waiting at least two extra days for the season to begin while severe weather causes delays can cause players some uneasiness.
"It's unfortunate," said Carl Pettersson. "I mean, this is crazy not being able to start. Hopefully we can get at least 54 holes in and make this thing official."
Article Links
The schedule calls for 36 holes today, and the final 18 on Monday.
"It would've been nice to play today, but it's Mother Nature," said John Huh. "You can't do anything about it."
Although play was canceled at around 10:30 a.m., Brandt Snedeker said he would take it easy during his time off due to the physical challenge the Plantation Course poses.
"I'm going to hop down to Lahaina a bit, but you want to stay as fresh as possible," Snedeker said. "Thirty-six holes around this golf course is a lot of tough walking, so you want to make sure you're well-rested. You have all this time to kill, but it's a double-edged sword."
Getting in
Gates will open for spectators at 6:45 a.m. today, and shuttles are to begin operating from the Honua Kai Resort and Spa at 6:30 a.m.
Each ticket for Friday or Saturday will be honored for today or Monday and can be exchanged at the gate.
For more information, call the tournament headquarters at 665-9160.


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A ribbon cutting and book signing was held Dec. 13 at The Center for Higher Learning for longtime local therapist Ray Goodenough.
Goodenough and his daughter, Kathy Rem, just published their book "Parallel Journeys." After 33 years of separation, the two were reunited and in this book they compare stories and realize what an incredible parallel journey they have undergone.
This event was organized by TahoeChamber catered by Exquisite Grill. For more information about The Center for Higher Learning, contact Ray Goodenough at 530-545-0809 or visit www.tahoetherapist.com.


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Top Definition
A magical school where brothers and sisters from Milton and Alpharetta come together and turn up. Lax bros think they're the shit and always get busted with MIP's or underage drinking. Dr Principal is one of the trillest niggas, he need mad respect. Athletic coach the dude all girls think it hot, he chill, but he aint know what to do but show kids movies for "education" teachers otherwise are young and some are pretty hot. The hallways are always crowded and parking lots are full or jeeps and trucks. The struggle is having a spot in the back.
Yo I go to Cambridge High school in Milton Georgia, not England.
Cambridge Bear가 작성 2013년 12월 22일 (일)
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5 more
The ABA helps judges improve and promote the judiciary, network, and stay abreast of current legal news.
The Judges' Journal keeps members current on issues affecting the courts and promotes discussion about the judicial process.
More Publications
The Model Code establishes ethical standards and provides structure to regulate conduct.
More New Books
Essays discuss the famous 1954 opinion that called for an end to segregated public schools.
More Constitutional Law Books


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I will be the first to say I hate Milbury. After watching the video it's an absolute embarrassment that Caps call him a captain, especially on that shift where the puck was in the offensive zone they scored on and he went for a line change.
Edited by darkmanx, 27 February 2013 - 10:23 PM.


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Skim, 2%, soy or coconut milk is served chilled or over ice. Simply refreshing.
|Calories 260
|Calories from Fat 90
|% Daily Value*
|Total Fat 10g
|Saturated Fat 5g
|Trans Fat 0g
|Cholesterol 40mg
|Sodium 250mg
|Total Carbohydrate 25g
|Dietary Fiber 0g
|Sugars 25g
|Protein 17g
|Caffeine 0mg**
|*Percent Daily Values are based on a 2,000 calorie diet.
|**Each caffeine value is an approximate value.
Nutritional information is calculated based on our standardized recipes. Because our beverages are handcrafted and may be customized, exact information may vary.
Nutritional information is calculated based on our standardized recipes. Because our beverages are handcrafted and may be customized, exact information may vary. Data is calculated using ESHA Research's Genesis® R&D software, and rounded to meet FDA regulations. Data for vitamins and minerals refers to percentage of U.S. Daily Values for a 2,000 calorie diet. Caffeine information is approximate and is based on limited analytical data. Caffeine values reflect our standard brewing methods; they can vary greatly based on the variety of the coffee and the brewing equipment used.
Allergen information is currently unavailable online for our beverage selections. If you have an allergen concern, please feel free to ask our baristas to check the ingredient labels or call 1-800-235-2883 for more information. Please note: we cannot guarantee that any of our beverages are allergen free because we use shared equipment and handle allergens throughout the store.
We cannot guarantee that any of our products are free from allergens (including dairy, eggs, soy, tree nuts, wheat and others) as we use shared equipment to store, prepare and serve them.
Did you know
No matter which kind of milk you choose, our 8 oz. servings provide about 300 mg of calcium each – roughly 30% of your recommended daily intake.
Currently Available


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Thursday, August 1, 2013
The Summerville based International Primate Protection League has received a wonderful gift – a remarkable collection of stamps from around the world. What makes the collection remarkable is that the only stamps in the collection are those that feature primates.
Baboons, chimpanzees, gibbons, spider, gorillas, and species most have never heard of. The stamps are from every country in the world including countries that no longer exist, says IPPL director Shirley McGreal.
The collection was bequeathed to the organization by David Rand – a long-time friend of McGreal's and an avid life-long collector of primate stamps.
"I first met David in Bangkok in 1975," says McGreal. "He has been a friend ever since."
Rand contracted a rare form of encephalitis while in the Far East and returned home to California, last year, where he died last October.
His brother Laury Rand contacted McGreal recently to ask if she would accept the collection and to tell her his brother had also bequeathed a third of his estate to IPPL to help fund primate protection organizations in Asia.
David Rand led a fascinating life, said McGreal. His brother says David had many avocations but "I am not sure if he had a vocation…what a wonderful way to live life."
"He was a tour director," said McGreal, "for wealthy American tourists to obscure places on unusual trips…off the beaten track."
In a farewell missive to family and friends, Rand wrote:
"In time, like an hour glass, the era inexorably nears the end of its reign and it tells those of us who are listening that 'your era is to be turned over to those who are younger, with more energy and spirit.'
My era is ending.
My wanderings have taken me to 299 countries; my airline hobby has permitted me to fly 1650 different air carriers.
My fascination with nature has allowed me to seek in the wild 70 percent of the world's species of primates and all the wild cats apart from the jaguar (#1 on my bucket list).
I have been able to send seven boys and girls to higher education and help set up scholarships for girls here in India, [so] that they get full apprenticeships and acceptance. Also, I have supported conservation projects for primates and their habitat.
Love and hope have ruled my efforts, also here in India, to improve the lives of street dogs in Orchha and elsewhere.
It is time to move on, within this era, and leave space to those younger and more clever.
As I move beyond this scope, I think back and thank you all and go out as one of the luckiest men on the face of the earth."
McGreal thinks everyone who knew him is pretty lucky and certainly IPPL, which has benefitted from his largesse.
"The stamps are just amazing," she says.
The collection, which Rand says he began during his first trans-African journey in 1972, includes more than 200 species as well as stamps that depict primates in art, statuary, cinema, space, literature, money, cartoons, computer games, masks and carvings. For each stamp, Rand has created a typewritten page telling the species, scientific name, diet, habitat, gestation, maturity, endangered or not, country found and miscellaneous information, where the stamp is from, the year it was issued and if there are any imperfections.
The earliest stamp in the collection, says Rand, is the first primate stamp from North Borneo issued in 1899.
A long-time customer of Stanley Gibbons Ltd. in London, the collection also includes many communications between Stanley Gibbons and Rand.
"We will never consider selling any of them," exclaimed McGreal. "They are his life's work."
They are kept under lock and key and they will build special locked cases to display them and keep them in a climate-controlled environment, she said.
McGreal is an old hand in the philatelic world – when she was a girl, she and her father used to collect stamps.
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