text:
|Back to Main Print This Page Email to a Friend
Osteoarthritis is a degenerative joint disease that typically affects joints in the knees, hip, hand, feet, and spine. It is the most common form of arthritis.
Risk Factors
Symptoms of osteoarthritis begin gradually and worsen slowly over time. Osteoarthritis pain is generally described as:
Osteoarthritis is usually diagnosed based on a physical exam and the results of x-rays. In some cases, the doctor may take a sample of synovial fluid from the joint.
There is no cure for osteoarthritis, but treatment can reduce pain and improve flexibility, joint movement, and quality of life. Treatment options include:
Acupunture for Pain Relief
Acupunture is an effective and reasonable option for treating chronic pain, according to a review of studies in the Archives of Internal Medicine. The pain conditions studied included osteoarthritis.
New Guidelines
In 2013, the American Academy of Orthopedic Surgeons (AAOS) released revised clinical practice guidelines for the treatment of osteoarthritis of the knee. Among the key recommendations:
Metal-on-Metal Hip Replacement
The FDA is currently reviewing the safety of "metal-on-metal" (metal ball and socket) components used in total hip replacement and hip resurfacing procedures. There have been reports that metal-on-metal components may increase complications such as pain and swelling.
Osteoarthritis, also known as degenerative joint disease, is the most common form of arthritis. In osteoarthritis, joints progressively lose cartilage, the slippery material that cushions the ends of bones.
As a result, the bone beneath the cartilage changes and develops bony overgrowth. The tissue that lines the joint can become inflamed, the ligaments can loosen, and the muscles around the joint can weaken. The patient feels pain and movement limitations when using the joint.
Joints provide flexibility, support, stability, and protection. Specific parts of the joint, the synovium and cartilage, provide these functions.
Synovium. The synovium is the tissue that lines a joint. Synovial fluid is a lubricating fluid that supplies nutrients and oxygen to cartilage.
Cartilage. The cartilage is a slippery tissue that coats the ends of the bones. Cartilage is composed of four components:
The combination of collagen and water forms a strong and slippery pad in the joint. This pad (meniscus) cushions the ends of the bones in the joint during muscle movement.
Osteoarthritis develops when cartilage in a joint deteriorates. The process is usually slow:
As the body tries to repair damage to the cartilage, other problems can develop:
Unlike some other types of arthritis, such as rheumatoid arthritis, osteoarthritis is less likely to involve many joints around the body or migrate from around one joint to another. Rather, it affects one or a few joints, usually joints that have received extra wear. Osteoarthritis affects joints differently depending on their location in the body.
The exact causes of osteoarthritis are not known. Scientists think that osteoarthritis likely develops from a combination of factors, including genetic susceptibility and joint injury.
The body's ability to repair cartilage declines with increasing age. Osteoarthritic cartilage is chemically different from normal cartilage. As chondrocytes (the cells that make cartilage) age, they lose their ability to repair damage and produce more cartilage. This process likely plays an important role in the development and progression of osteoarthritis.
Osteoarthritis tends to run in families. Genetic factors may be involved in about half of osteoarthritis cases in the hands and hips, and in a somewhat lower percentage of cases in the knee. Several genes that might contribute to an inherited risk are under investigation.
The inflammatory response is an overreaction of the immune system to an injury or other assault in the body, such as an infection. This response causes specific immune factors, called cytokines, to gather in injured areas and cause inflammation and damage to body tissue and cells. The inflammatory response plays an important role in rheumatoid arthritis and other muscle and joint problems associated with autoimmune diseases.
Inflammation probably plays at most a minor role in the early stages of osteoarthritis and is more likely to be a result -- not a cause -- of the disease. However, inflammation may contribute to the progression of osteoarthritis and in its chronic nature. The effects of the inflammatory response in osteoarthritis are likely to be different, and less severe, than those in rheumatoid arthritis.
Joint damage from injuries or recurrent stress to the joint is often the starting point in the osteoarthritis disease process. Osteoarthritis sometimes develops years after a single traumatic injury to or near a joint. Patients with knee injuries may be up to five times more likely to develop osteoarthritis in the injured knee than those without injuries, and patients with hip injuries may be more than three times more likely to develop arthritis in the injured hip. Proper treatment of injuries may help prevent the development of osteoarthritis.
Other causes of osteoarthritis include:
Osteoarthritis can affect people of any age, but it is much more common in older people. It rarely occurs in people younger than age 40.
In people younger than 45, osteoarthritis occurs more frequently in men. After age 45, it develops more often in women. Some research suggests that women may experience greater muscle and joint pain than men.
Obesity increases the risk for osteoarthritis. It also worsens osteoarthritis once deterioration begins. This higher risk is due to increased weight on the joints.
Because injuries can trigger the disease process, people whose work or leisure activities place them at risk for muscle and joint injuries may face a higher risk for osteoarthritis later on.
Occupational Risks. Certain occupations with repeated stressful motions (such as squatting or kneeling with heavy lifting) can contribute to the deterioration of cartilage. People with jobs that require kneeling or squatting for more than an hour a day are at high risk for knee osteoarthritis. Jobs that involve lifting, climbing stairs, or walking also pose some risk.
Exercise. There has been some question about the role of strenuous exercise in osteoarthritis. Sports that definitely pose a higher risk for osteoarthritis have repetitive or direct joint impact (such as football), joint twisting, or both (baseball pitching, soccer).
Regular and moderate exercise, however, is important for everyone and does not increase the risk for osteoarthritis. Recreational weight-bearing exercise (walking, jogging), done by middle-aged and elderly people, neither prevents osteoarthritis nor increases risk. Furthermore, many factors associated with a sedentary life (such as muscle weakness and obesity) are associated with a higher risk for osteoarthritis.
The pain of osteoarthritis typically begins gradually after age 40 and progresses slowly over many years. Younger people with the condition may have no symptoms at all. Osteoarthritis is commonly identified by the following symptoms:
Hand. Osteoarthritis of the hand occurs most often in older women and may be inherited within families. The following joints are most frequently affected:
Osteoarthritis of the hand may predict the later development of osteoarthritis in the hip or knee.
Knee. Osteoarthritis is particularly debilitating in the weight-bearing joints of the knees. The meniscus, the cartilage pad between the joint formed by the thighbone and the shinbone, plays an important role in protecting this joint. It acts as a shock absorber. The joint is usually stable until the disease reaches an advanced stage when the knee becomes enlarged and swollen. Although painful, the arthritic knee usually retains reasonable flexibility.
Hips. About 1 in 4 people develop hip arthritis over the course of their lifetime. Being obese increases the risk. Osteoarthritis frequently strikes the weight-bearing joints in one or both hips. Pain develops slowly, usually in the groin and on the outside of the hips, or sometimes in the buttocks. The pain also may radiate to the knee, confusing the diagnosis. Those with osteoarthritis of the hip often have a restricted range of motion (particularly when trying to rotate the hip) and walk with a limp, because they slightly turn the affected leg to avoid pain.
Spine. Osteoarthritis may affect the cartilage in the disks that form cushions between the bones of the spine, the moving joints of the spine itself, or both. Spinal osteoarthritis can affect the neck (cervical), mid-back (thoracic), or lower back (lumbar) regions. Osteoarthritis in any of these locations can cause pain, muscle spasms, and diminished mobility. In some cases, the nerves may become pinched, which produces radiating pain. Advanced disease may result in numbness and muscle weakness.
Shoulder. Osteoarthritis is less common in the shoulder area than in other joints, but it may develop in the shoulder joint (the glenohumeral joint). In such cases, it is most often associated with a previous injury, and patients gradually develop pain and stiffness in the back of the shoulder. Osteoarthritis also can develop in the acromioclavicular (AC) joint, which is between the shoulder blade and the collarbone. However, it rarely causes symptoms in this location.
Osteoarthritis is diagnosed based on physical symptoms, medical history, and x-ray images. Other tests may also be performed.
Your doctor will ask you about the type of pain you experience, when it occurs, how long it lasts, and whether you have ever injured the joint.
In osteoarthritis, the affected joint is generally tender to pressure right along the joint line. Joint movement may cause a crackling sound. The bones around the joints may feel larger than normal. The joint's range of motion is often reduced, and normal movement is often painful.
Osteoarthritis is often visible in x-rays. Cartilage loss is suggested by certain characteristics of the images:
Some people may have osteoarthritis even though it does not show up on an x-ray. Likewise, other people may have minimal symptoms even though an x-ray clearly shows they have osteoarthritis.
An MRI exam of an arthritic joint is generally not needed, unless the doctor suspects other causes of pain.
If the diagnosis is uncertain or infection is suspected, your doctor may recommend taking a sample of synovial fluid from the joint. The doctor inserts a sterile needle into the joint and withdraws the synovial fluid into a syringe attached to the needle. The fluid is sent to a laboratory for analysis:
Blood test results may help identify other types of arthritis besides osteoarthritis. Some examples include:
Numerous conditions cause symptoms of joint aches and pains. Something as simple as sleeping on a bad mattress or as serious as cancer can mirror symptoms of osteoarthritis. Other problems that can cause aches and pains in the joints include physical injuries, infections, tendinitis, and poor circulation.
Osteoarthritis can generally be distinguished from other joint diseases by considering several factors together:
Below are a few of the most common disorders that can be confused with, or may even accompany, osteoarthritis.
Rheumatoid Arthritis. Osteoarthritis can be confused at times with milder forms of rheumatoid arthritis, particularly when osteoarthritis affects multiple joints in the body. Rheumatoid arthritis normally occurs earlier in life than osteoarthritis, often striking people in their 30s and 40s. Rheumatoid arthritis affects many joints, and often occurs symmetrically on both sides of the body. People with rheumatoid arthritis generally have morning stiffness that lasts for at least an hour. (Stiffness from osteoarthritis usually clears up within half an hour.) Although osteoarthritis can occasionally cause swollen, red joints, this appearance is much more typical of rheumatoid arthritis and other types of inflammatory arthritis. In addition to blood tests, x-rays can help show differences between rheumatoid arthritis and osteoarthritis.
Chondrocalcinosis (Pseudogout). Chondrocalcinosis (pseudogout syndrome) is a disease in which a certain type of calcium crystal known as CPPD (calcium pyrophosphate dihydrate) accumulates in the joints. This condition can accompany and even worsen osteoarthritis. Chondrocalcinosis is also called pseudogout or pseudo-osteoarthritis, the latter particularly when it affects the knees. A doctor can usually differentiate between the two disorders because chondrocalcinosis usually damages other joints (such as wrists, elbows, and shoulders) that are not normally affected by osteoarthritis.
Charcot's Joint. Charcot's joint occurs when an underlying disease, usually diabetes, causes nerve damage in the joint, which leads to swelling, bleeding, increased temperature, and changes in bone. There may be a loss of sensation that leads to an increased risk of injury from overuse. The nerve pain associated with Charcot's joint may be mistaken for osteoarthritis.
There is no cure for osteoarthritis, but there are many treatments that can relieve symptoms and significantly improve the quality of life.
The goals of osteoarthritis treatment are to reduce pain and improve joint function. Treatment approaches include:
Lifestyle changes can help reduce stress on affected joints.
Joints need motion to stay healthy. Long periods of inactivity cause the arthritic joint to stiffen and the adjoining tissue to atrophy (waste away). A moderate exercise program that includes low-impact aerobics and power and strength training has benefits for patients with osteoarthritis, even if exercise does not slow down the disease progression. Exercise helps:
Exercise especially helps patients with mild-to-moderate osteoarthritis in the hip or in the knee. Many patients who begin an aerobic or resistance exercise program report less disability and pain. They are better able to perform daily chores and remain more independent than their inactive peers. Older patients and those with medical problems should always check with their doctors before starting an exercise program.
Three types of exercise are best for people with osteoarthritis:
Strengthening and Resistance Exercise. Strengthening exercises include isometric exercises (pushing or pulling against static resistance). Isometric training builds muscle strength while burning fat, helps maintain bone density, and improves digestion. For patients with arthritis in the hip or knees, exercises that strengthen the muscles of the upper leg are important.
Range-of-Motion Exercise. These exercises increase the amount of movement in joints. In general, they are stretching exercises. The best examples are yoga and tai chi, which focus on flexibility, balance, and proper breathing.
Aerobic Exercise. Aerobic exercises help control weight and may reduce inflammation in some joints. Low-impact workouts also help stabilize and support the joint. Cycling, walking, elliptical training, and cross-country skiing are beneficial for people with osteoarthritis, and swimming or exercising in water is highly recommended. Patients with osteoarthritis should avoid high-impact sports such as jogging, tennis, and racquetball if they cause pain.
In addition to exercise, treatment of muscles and joints by a physical therapist can be helpful. An occupational therapist can show you ways to more easily perform daily tasks of living without putting stress on your joints. Your therapist can recommend how to make changes in your workplace or work tasks to avoid repetitive or damaging motions.
Overweight patients with osteoarthritis can lessen the shock on their joints by losing weight. Knees, for example, sustain an impact three to five times the body weight when descending stairs. Losing 5 pounds of weight can eliminate 20 pounds of stress on the knee. The greater the weight loss, the greater the benefit. The American Academy of Orthopedic Surgeons recommends that patients with a body mass index (BMI) greater than 25 should try to lose at least 5% of their body weight.
Ice. When a joint is inflamed (particularly in the knee) applying ice for 20 - 30 minutes can be helpful. If an ice pack is not available, a package of frozen vegetables works just as well.
Heat Treatments. Soaking in a warm bath or applying a heating pad may help relieve stiffness and pain.
A wide variety of devices are available to help support and protect joints, although it is unclear how effective they are. They include splints or braces, and shoe inserts or orthopedic shoes. An offloading (also called unloading) brace is commonly used for knee osteoarthritis to help transfer the weight off the affected joint.
There are many different types of assisted devices that can help make your life easier in the home. Kitchen gadgets, such as jar openers, assist with gripping and grabbing. Door-knob extenders and key turners are helpful for patients who have trouble turning their wrists. Bathrooms can be fitted with shower benches, grip bars, and raised toilet seats. An occupational therapist can advise you on choosing the right kinds of assistive devices.
Relaxation techniques such as guided imagery and breathing exercises may help some patients better cope with chronic pain.
Some patients use acupuncture to reduce osteoarthritis pain. The technique is painless and involves the insertion of small fine needles at select points in the body. Some studies have found that acupuncture is effective for treating chronic pain and can help provide pain relief for osteoarthritis.
Transcutaneous electric nerve stimulation (TENS) uses low-level electrical pulses to suppress pain. A variant (sometimes called percutaneous electrical nerve stimulation, or PENS) applies these pulses through a small needle to acupuncture points. Some patients with knee osteoarthritis find this treatment helpful.
Ultrasound therapy uses high-energy sound waves to produce heat within the tissue, which may help reduce inflammation, relieve pain, and improve function. Therapeutic ultrasound is usually performed by a physical therapist using an ultrasound machine. The therapist applies gel to the affected area and moves a handheld ultrasound transducer over the joint. There is evidence that therapeutic ultrasound is beneficial for patients with knee osteoarthritis.
Massage therapy may help provide short-term pain relief for some patients. It is important to work with an experienced massage therapist who understands how not to injure sensitive joint areas.
Glucosamine and Chondroitin. Glucosamine hydrochloride and chondroitin sulfate are natural substances that are part of the building blocks found in and around cartilage. For many years, researchers have been studying whether these dietary supplements really work for relieving osteoarthritis pain. Earlier studies suggested a potential benefit from these supplements.
However, more recent high-quality studies involving large numbers of patients have indicated that glucosamine and chondroitin, either alone or in combination, do not seem to work any better than a placebo for relieving symptoms of osteoarthritis. Based on these studies, the American College of Rheumatology does not recommend the use of these supplements. Some doctors suggest a trial period of three months to see if glucosamine and chondroitin work. If the patient does not experience any benefit, the supplements should be discontinued.
S-adenosylmethionine (SAMe). S-adenosylmethionine (SAMe, pronounced "Sammy") is a synthetic form of a natural byproduct of the amino acid methionine. It has been marketed as a remedy for arthritis, but scientific evidence supporting these claims is lacking.
Generally, manufacturers of herbal remedies and dietary supplements do not need FDA approval to sell their products. Just like a drug, herbs and supplements can affect the body's chemistry, and therefore have the potential to produce side effects that may be harmful. There have been several reported cases of serious and even lethal side effects from herbal products. Always check with your doctor before using any herbal remedies or dietary supplements.
Acetaminophen (Tylenol, generic) is the first choice for treating mild-to-moderate osteoarthritis pain. (Acetaminophen may be less effective than NSAIDs in reducing moderate-to-severe pain.) Because acetaminophen has fewer side effects, most doctors suggest trying this drug first, then switching to an NSAID if acetaminophen does not provide sufficient pain relief. Acetaminophen is an analgesic that helps relieve pain but unlike NSAIDs it does not help reduce inflammation.
Side Effects. Acetaminophen is inexpensive and generally safe. It poses far less of a risk for gastrointestinal problems than NSAIDs.
The daily dose of acetaminophen should not exceed 3,000 mg. Patients who take high doses of this drug for long periods are at risk for liver damage, particularly if they drink alcohol and do not eat regularly. Long-term, high-dose acetaminophen therapy may increase the risk for high blood pressure.
Nonsteroidal anti-inflammatory drugs (NSAIDs) block prostaglandins, the substances that dilate blood vessels and cause inflammation and pain. There are dozens of NSAIDs:
Oral NSAIDs should be used only for a short period of time. Long-term use of NSAIDs does not delay the progression of osteoarthritis and can increase patients' risk of side effects.
Patients should use only the lowest effective dose because high dosages of NSAIDs can cause heart problems (such as increased blood pressure and risk of heart attack), kidney problems, and stomach bleeding. Because of these risks, the American College of Rheumatology recommends using topical NSAIDs in place of oral NSAIDs for patients 75 years and older.
Patients who take daily low-dose aspirin for heart protection should consider using an oral NSAID other than ibuprofen. Ibuprofen may make the aspirin less effective.
Patients who are at increased risk of stomach bleeding and ulcers should either switch to another type of pain reliever, or take the NSAID along with a proton-pump inhibitor drug, such as omeprazole (Prilosec, generic) or esomeprazole (Nexium), an H2 blocker such as famotidine (Pepcid, generic), or with the synthetic prostaglandin misoprostol (Cytotec, generic). (Misoprostol can cause miscarriage and should not be used by women who may be pregnant.) Some NSAIDs are available as combination pills; they include diclofenac/misoprostol (Arthrotec) and ibuprofen/famotidine (Duexis).
Capsaicin is a component of hot red peppers and may bring pain relief when used as a skin cream (Zostrix, generic). This is the only skin preparation that does more than just mask pain or reduce it temporarily. Capsaicin seems to reduce a substance in the body, known as substance P, which contributes both to inflammation and the delivery of pain impulses from the central nervous system.
A small amount of capsaicin must be applied to the area of inflammation about four times a day. During the first few days of use, the patient will experience a warm, stinging sensation when the cream is applied. This sensation goes away, and pain relief usually begins within 1 - 2 weeks. The American College of Rheumatology recommends topical capsaicin for hand osteoarthritis but not for knee or hip osteoarthritis.
Topical over-the counter joint pain relievers that contain menthol, methyl salicylate, and (less commonly) capsaicin may in rare cases cause chemical burns. Menthol and methyl salicylate products are sold under brand names such as Bengay, Flexall, Icy Hot, and Mentholatum. Products that contain capsaicin include Capzasin as well as Zostrix. The risks appear more severe for combination products that contain higher doses of both menthol (greater than 3%) and methyl salicylate (greater than 10%). The FDA recommends:
These warnings also apply to the topical NSAID products that contain trolamine salicylate (see NSAIDs section above).
Duloxetine (Cymbalta) is a serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant that is used to treat depression, anxiety disorders, diabetic nerve pain, and fibromyalgia. In 2010, the FDA approved duloxetine for treatment of chronic musculoskeletal pain associated with osteoarthritis.
Tramadol (Ultram, generic) is a pain reliever that has been used as an alternative to opioids. It has opioid-like properties but is not as addictive. (Dependence and abuse have been reported, however.) It can cause nausea but does not cause severe gastrointestinal problems, as NSAIDs can. Some patients experience severe itching. A combination of tramadol and acetaminophen (Ultracet, generic) is available.
Narcotics, pain-relieving and sleep-inducing drugs that act on the central nervous system, are the most powerful medications available for the management of moderate-to-severe pain. There are two types of narcotics:
Although the use of narcotics for arthritic pain is controversial, they may have a place in osteoarthritis treatment when milder drugs are not effective or appropriate. These drugs can be highly addictive, and should be prescribed at the lowest possible effective dose.
Common side effects include anxiety, constipation, nausea and vomiting, dizziness, drowsiness, paranoia, urinary retention, restlessness, and labored or slow breathing.
When pain becomes a major problem and less potent pain relievers are ineffective, doctors may try corticosteroid (steroid) injections into the joint. Corticosteroid shots are useful only if inflammation is present in the joint. Relief from pain and inflammation is of short duration, and this treatment is rarely used for chronic osteoarthritis. The American College of Rheumatology does not recommend these injections for hand osteoarthritis.
Corticosteroid injections are usually given every 3 months. Patients should not have more than two or three injections a year, since there is some concern that repeated injections over the long term may be harmful. Because long-term use of corticosteroids has many potentially serious side effects, steroid medications are never given by mouth (systemically) for the treatment of osteoarthritis.
Injections of hyaluronic acid (such as Hyalgan, Synvisc, Artzal, and Nuflexxa) into the joint -- a procedure called viscosupplementation – are a controversial treatment for knee osteoarthritis. Evidence indicates that these injections provide only very modest short-term pain relief at best. Some studies suggest these injections may increase the risk for swelling and inflammation. The American Academy of Orthopedic Surgeons no longer recommends viscosupplementation as a treatment for patients with symptomatic osteoarthritis of the knee.
If lifestyle measures and medications fail to relieve pain and increase function, surgery may be an option. Certain surgical procedures can help relieve pain if medications fail. Even with these procedures, however, joint replacement may still be needed later on.
When osteoarthritis becomes so severe that pain and immobility make normal functioning impossible, many people become candidates for artificial (prosthetic) joint implants using a procedure called arthroplasty. Arthroplasty involves removing the surfaces of the joint and replacing them with an artificial material made of metal, plastic, or other material.
Hip replacement is the most established and successful replacement procedure, followed by knee replacement. Other joint surgeries (such as shoulders, elbows, wrists, and fingers) are less common, and some arthritic joints (in the spine, for instance) cannot yet be treated in this manner..
Candidates. In evaluating the need for surgery, a patient's pain and disability are more important considerations than age or other factors (such as weight).
Joint replacement is effective for patients of all ages. While older patients may take longer to achive full recovery than younger people, the long-term outcome of the surgery is usually excellent, and can lead to significant improvements in pain and quality of life. In the past, surgeons have generally recommended delaying joint replacement for younger patients, because of concern of implants wearing out and the patient requiring an additional revision procedure later on. Newer, longer-lasting materials are, however, helping reduce the need for revision operations.
Complications. Complications can occur, and, although uncommon, some can be life threatening. In addition to blood loss and infection, deep blood clots in the legs (deep venous thrombosis) are a serious potential complication. These clots can potentially travel to the lungs (pulmonary embolism) and pose a risk for death. Patients who are overweight are at higher than average risk for blood clots.
Metal ball and socket components are sometimes used in both total hip replacement and hip resurfacing procedures. The FDA is currently reviewing the safety of these "metal-on-metal" components to see if they increase swelling and pain. There is also concern that metal ions (particles) may be released into the bloodstream, where they might trigger allergic reactions and other problems. Talk with your surgeon about the type of materials that will be used in your procedure and their possible risks and benefits. If you experience any swelling or pain after surgery, be sure to notify your doctor.
Recovery and Rehabilitation. Aside from the surgeon's skill and the patient's underlying condition, the success rate depends on the kind and degree of activity the joint receives following replacement surgery. Physical therapy takes about 6 weeks to rebuild adjoining muscle and strengthen surrounding ligaments. Patients typically experience considerable pain during this time.
While many patients find that joint replacement eventually provides pain relief and restores some mobility, they need time to adjust to the artificial joint.
Limitations after hip surgery include:
Limitations after knee surgery include:
Minimally Invasive Arthroplasty. Surgeons are exploring a variety of new techniques for a "minimally invasive" approach to knee and hip arthroplasty. They include using a shorter incision, and new types of smaller specialized instruments. The goal is to give the patient a shorter recovery time and less postoperative pain. However, minimally invasive arthroplasty is still in its early stages. At this time, there is no consensus on which minimally invasive technique works best, or if it actually achieves any additional benefits beyond the recovery period.
Alternatives to Total Joint Replacement. Surgical alternatives to total knee or hip joint replacement include:
Osteotomy is a surgical procedure used to realign bone and cartilage and reposition the joint to help transfer weight from a damaged to healthy part of the knee. The procedure involves making a cut in one of the bones in the lower leg and removing a slice of bone to straighten the leg:
Osteotomy is generally performed for early-stage knee osteoarthritis that has affected only a certain section (compartment) of the knee. According to the American Academy of Orthopedic Surgeons, this procedure works best for patients who are thin, active, or younger (40 – 60 years old).
If the affected joint cannot be replaced, surgeons can perform a procedure called arthrodesis that eliminates pain by fusing the bones together. The patient must understand, however, that fusing the bones makes movement of the joint impossible. Bone fusion is most often done in the spine and in the small joints of the hands and feet.
Arthroscopy with lavage and debridement is sometimes performed to clean out bone and cartilage fragments that, in theory at least, may cause pain and inflammation. Arthroscopy is also sometimes used to diagnose osteoarthritis. In this procedure, the surgeon makes a small incision and inserts the arthroscope, a pencil-width fiber-optic instrument that contains a light and magnifying lens. The arthroscope is attached to a miniature television camera that allows the surgeon to see the inside of the joint. Saline solution is injected to wash out the debris (lavage) and the fragments are then removed (debridement).
Research and debate continues on whether arthroscopy is truly helpful for osteoarthritis and, if so, which patients may benefit the most from it. Most guidelines do not recommend this treatment for patients who have symptoms of osteoarthritis but no other problems such as loose fragments or meniscus tears. Arthroscopy may possibly benefit people with mild-to-moderate osteoarthritis who have bone and cartilage fragments in the joint, or patients whose joints lock or catch with movement
American Academy of Orthopedic Surgeons (AAOS). Treatment of osteoarthritis of the knee: Evidence-based guideline 2nd edition (summary). Rosemont, IL. Published May 18, 2013.
Bozic KJ, Browne J, Dangles CJ, Manner PA, Yates AJ Jr, Weber KL, et al. Modern metal-on-metal hip implants. J Am Acad Orthop Surg. 2012 Jun;20(6):402-6.
Brouwer RW, Raaij van TM, Bierma-Zeinstra SM, et al. Osteotomy for treating knee osteoarthritis. Cochrane Database Syst Rev. 2007;(3):CD004019.
Cepeda MS, Camargo F, et al. Tramadol for osteoarthritis: a systematic review and metaanalysis. J Rheumatol. 2007;34(3):543-555.
Das A, Neher JO, Safranek S. Clinical inquiries. Do hyaluronic acid injections relieve OA knee pain? J Fam Pract. 2009 May;58(5):281c-e.
Fransen M, McConnell S. Exercise for osteoarthritis of the knee. Cochrane Database Syst Rev. 2008 Oct 8;(4):CD004376.
Hernández-Molina G, Reichenbach S, Zhang B, Lavalley M, Felson DT. Effect of therapeutic exercise for hip osteoarthritis pain: results of a meta-analysis. Arthritis Rheum. 2008 Sep 15;59(9):1221-8.
Hochberg MC, Altman RD, April KT, Benkhalti M, Guyatt G, McGowan J, et al. American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip,
and knee. Arthritis Care Res (Hoboken). 2012 Apr;64(4):455-74.
Izquierdo R, Voloshin I, Edwards S, Freehill MQ, Stanwood W, Wiater JM, et al. The treatment of glenohumeral joint osteoarthritis: guideline and evidence report. American Academy of Orthopedic Surgeons. 2009 Dec 5; v1.0.
Lane NE. Clinical practice. Osteoarthritis of the hip. N Engl J Med. 2007;357(14): 1413-1421.
Lange AK, Vanwanseele B, Fiatarone Singh MA. Strength training for treatment of osteoarthritis of the knee: a systematic review. Arthritis Rheum. 2008 Oct 15;59(10):1488-94.
Laupattarakasem W, Laopaiboon M, Laupattarakasem P, et al. Arthroscopic debridement for knee osteoarthritis. Cochrane Database Syst Rev. 2008;(1):CD005118.
Leopold SS. Minimally invasive total knee arthroplasty for osteoarthritis. N Engl J Med. 2009 Apr 23;360(17):1749-58.
Manheimer E, Cheng K, Linde K, Lao L, Yoo J, Wieland S, et al. Acupuncture for peripheral joint osteoarthritis. Cochrane Database Syst Rev. 2010 Jan 20;(1):CD001977.
Rutjes AW, Jüni P, da Costa BR, Trelle S, Nüesch E, Reichenbach S. Viscosupplementation for osteoarthritis of the knee: a systematic review and meta-analysis. Ann Intern Med. 2012 Jun 11. [Epub ahead of print]
Pivec R, Johnson AJ, Mears SC, Mont MA. Hip arthroplasty. Lancet. 2012 Nov 17;380(9855):1768-77. Epub 2012 Sep 26.
Rutjes AW, Jüni P, da Costa BR, Trelle S, Nüesch E, Reichenbach S. Viscosupplementation for osteoarthritis of the knee: a systematic review and meta-analysis. Ann Intern Med. 2012 Aug 7;157(3):180-91. [Epub ahead of print]
Rutjes AW, Nüesch E, Sterchi R, Jüni P. Therapeutic ultrasound for osteoarthritis of the knee or hip. Cochrane Database Syst Rev. 2010 Jan 20;(1):CD003132.
Sinusas K. Osteoarthritis: diagnosis and treatment. Am Fam Physician. 2012 Jan 1;85(1):49-56.
Vickers AJ, Cronin AM, Maschino AC, Lewith G, MacPherson H, Foster NE, et al. Acupuncture for chronic pain: individual patient data meta-analysis. Arch Intern Med. 2012 Oct 22;172(19):1444-53.
Wandel S, Jüni P, Tendal B, Nüesch E, Villiger PM, Welton NJ, et al. Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysis. BMJ. 2010 Sep 16;341:c4675. doi: 10.1136/bmj.c4675.
On a mission to heal body, mind and spirit


text:
Systemwide Events Calendar
103rd Annual Commencement Exercises- UndergraduateMay 17, 9:00am - 12:00pm
Manoa Campus, Stan Sheriff Center
Join us as we celebrate the degree candidacy of UH Manoa's 103rd Annual Graduating Class.
Undergraduate Degree Ceremony: 9 a.m. - 12 p.m. Can't attend the undergraduate ceremony? Link to the webcast of the undergraduate ceremony: http://www.hawaii.edu/dl/commencement/.
Campus parking will be free.
For disability access, or more information, visit the commencement website. http://manoa.hawaii.edu/commencement/
Event Sponsor
Office of the Chancellor, Manoa Campus
More Information
956-3889, firstname.lastname@example.com, http://manoa.hawaii.edu/commencement/
|Saturday, May 17
|Beach Clean-Up with Waikiki Aquarium
Manoa Campus, Kapiolani Park
|103rd Annual Commencement Exercises- Undergraduate
Manoa Campus, Stan Sheriff Center
|Rain Gardens for Island Home Landscapes
Manoa Campus, Lyon Arboretum, 3860 Manoa Rd.
|Papa La`au Lapa`au - Hawaiian Medicine Class, Section 2
Manoa Campus, Lyon Arboretum
|103rd Annual Commencement Exercises- Advanced Degree
Manoa Campus, Stan Sheriff Center
- Highlighted dates have scheduled events.
- Select the date to view all events for that day.

subset: commoncrawl


text:
HUSQVARNA 346XP Parts List Manual Download
Quick Overview
Husqvarna 346XP Workshop Manual Tired of paying high repair cost to your mechanic to fix your HUSQVARNA CHAINSAW? If so, we have the perfect solution for you. Here is a workshop manual to fix and or service your HUSQVARNA CHAINSAW. These manuals contain photos and diagrams as used by professional mechanics and repair shops to troubleshoot and fix your chainsaw. These manuals have plenty of pictures and diagrams to make the entire repair process easy for you.
Stihl Manual PDF Download
Models Covered HUSQVARNA 346XP Parts list Manual Download Tired of paying high repair cost to your mechanic to fix your HUSQVARNA CHAINSAW? If so, we have the perfect solution for you. Here is a parts list manual to help you fix and or service your HUSQVARNA 346XP CHAINSAW. Contents: • Chain Brake • Clutch/Drum • Oil pump • Top Cover • Piston/cylinder • Crankshaft • Muffler • Air Filter/Carburettor • Crankcase • Front Handle • Fuel Tank/rear handle • Ignition/Flywheel • Starter • Carburettor Parts • Accessories • Parts listing These manuals contain photos and diagrams as used by professional mechanics and repair shops to troubleshoot and fix your chainsaw. Save money by doing your own repairs Diagrams, exploded parts lists, manuals all in pdf format. To save or print at any time, Can be used as guides for other models. For different models information may be some or all of above Covers every detail Routine maintenance of your outdoor power equipment has several benefits: Improves engine performance, Reduces fuel consumption by up to 30%, Reduces emissions by up to 50%, and more. Easy to navigate and print Plus much more information The manual gives comprehensive information on your parts for HUSQVARNA and much more. At the click of a mouse you have access to the most comprehensive diagnostic, repair and maintenance information as used by professional mechanics, technicians and repair workshops. Very clear and precise diagrams and instructions, they are designed to get the information you need quickly and easily. Covering all applicable models to view and print. This item is a download please give a valid email when ordering. We have more manuals in our shop, please use the navigation or search on this page. For downloads there are available for 7 retries and 7 day's availability, any download issues you may have please email us here Please note this is a downloadable item, this is compressed, you may require winrar or other available to unzip, uncompress it. Get it free from our free stuff page here This uses Doc. or PDF format. Reader available for free from our free stuff page here Keywords: HUSQVARNA CHAINSAW, chainsaw manual, manual HUSQVARNA 346XP, HUSQVARNA 346XP repair guide, HUSQVARNA 346XP workshop manual, HUSQVARNA parts, HUSQVARNA 346XP operators manual, HUSQVARNA 346XP service manual, HUSQVARNA 346XP parts list.


text:
I have been churning the thoughts of Montreal in head for the last day, trying to decide how to review the second night U2 show. The only benefit I can find to spending a far-too-limited amount of time in that great city is that my mind is not so crowded of memories of Montreal and its sites, so I still have U2 in my head. That city and Quebec deserve so much more recognition than I can give them here. I had a wonderful time, did not feel uncomfortable because I do not speak French, and I cannot wait to return. I will say again, the people of Montreal were so friendly, helpful and proud. They obviously enjoy life and want you to as well. They make ideal U2 fans, and being with 40,000 of them in the General Admission (GA) section at the Hippodrome was a wonderful thing.
(The easiest way to review the night is song by song with my thoughts intermixed. I'm not going to bother with any focus on security and poor event planning. My Friday night show review was enough of that. Moment Of Soggy, U2 In Montreal Night 1)
I don't know much of their music, but I can say that I don't feel it translates well to a stadium setting. They are a tight band and play well together. I wish them luck, but they failed to inspire me and those around me both nights.
1. Space Oddity Intro – The crowd now knows that this is the lead-in to U2's entrance and sing along in anticipation. It was very fun to feel it.
2. Even Better Than The Real Thing – U2 arrived on stage and ripped into this Achtung Baby hit.
3. The Fly –The CLAW came alive in a strobing mass. This song was kind of a dud when it was released as the first single off Achtung Baby. It was too "different" of U2. Now, it is a monster hit live and a favorite of many.
4. Mysterious Ways –The new video for this song fits well with Montreal's Cirque du Soleil's celebration of the human animal. The beautiful dancer is morphed and modified to match well with the songs lyrics. For a song I've heard live many times, this reinvigorates it nicely.
5. Until The End Of The World –The final string of Achtung Baby opening songs got the crowd pumped for the rest of the night. I was eager to hear what is next because I know U2's second nights bring fun changes.
6. Out Of Control –U2's first single sounds great, and they played it with good energy. It's nice to hear a rare tune in the setlist on the tour because the band usually puts a little something extra in it.
Out Of Control Montreal video link
7. Get On Your Boots –A Sikh fan was pulled up on stage and didsn't miss a beat with his shout of "I don't want to talk about wars between nations!" Bono was impressed. I found out later that he is a long-time fan and well known among those that regularly camp out for U2 shows. That had to be one of the best moments of his life.
"Tonight we want to give you as a gift to the world," says Bono. The show is to be simulcast on U2.com to subscribers. "When we were kids, joining U2 was like running away with the circus. Now, maybe we need to find another circus." In the home of Cirque du Soleil, he takes this time to introduce the band members and speculates on what they would be in a circus:
Larry would be a fire-eater. A sword-swallower? World's strongest man?
Adam would be the bearded lady.
Edge would be a trapeze artist. A high-wire walker. Edge responds with "a knife thrower."
"And, I will play the clown," says Bono modestly, a reference to the video of the next song.
8. All I Want Is You –Bono finished this beautiful song with some soft harmonica playing.
9. Stuck In A Moment –"For a great friend, Michael Hutchence," states a saddened Bono. Hutchence was the long-time lead singer of INXS who took his own life in 1997.
10. Beautiful Day –This song has been popular and a tour staple since Elevation, but it has an extra richness and passion since this tour's addition of Commander Mark Kelly's introduction of it in the International Space Station and the dedication of it Kelly's wife Gabrielle Giffords who was shot in the head in an assassination attempt in January of this year. I have seen this intro and song five times now, and it has never failed to bring me to tears. Thankfully, Beautiful Day is an uplifting song and raises my spirit and the crowd's.
11. Elevation –As if they planned on keeping our spirits high, the band kept the momentum going with this simple, fun song.
12. New Year's Day –Again, as with Out Of Control, this song makes a special appearance in U2's show and has a reinvigorated feel to it.
13. Miss Sarajevo –The only possible negative thing I can say for this night is that Bono should stop singing this song. For two nights in a row, he messed up the lyrics of this deeply emotion tune. It deserves better than that.
14. Zooropa –The transition from Miss Sarajevo to Zooropa is a brilliant series of overlapping questions posed by different voices, including Stephen Hawking's "Is history bound to repeat itself?" I love the transition and may forgive Bono's mistakes. Zooropa is a precious gem of a song to me, and special to many of U2's fans for its uniqueness and insightful damning of our consumer-driven world. Greatness!
15. City Of Blinding Lights –The complex and beautiful video screen that is the centerpiece of the 360 CLAW stage extended downward for Zooropa and lit up with bright, glowing colors, fittingly for this song.
16. Vertigo –Continuing the high they were put on by City Of Blinding Lights (COBL), Montrealers went crazy for Vertigo. The Hippodrome was filled with bouncing and singing fans.
17. Crazy Tonight Remix –This three-song grouping (COBL, Vertigo and Crazy Tonight) is the most energetic part of the night. The crowd needed no more motivation, but the dancing continued through this remix. I am proud and amazed that the band ever took such a risk with this. What easily could have been a flop has been the most memorable part of this tour for some and speaks to U2's inventiveness and willingness to experiment and take chances.
18. Sunday Bloody Sunday –I am so glad to see the crowd absolutely devour this song. It holds very little meaning or interest for me anymore, so I am glad that I can enjoy other people enjoying it.
19. Scarlet –This is a rare track and an odd choice to include in a concert. U2 makes it work, especially tonight with an energetic Bono singing, "Rejoice!" The crowd was happy to join him.
20. Walk On –The freeing of Burma's legitimately elected leader, Aung San Suu Kyi, has transformed this from a song of hope to a song of celebration. We are reminded by the video screen that there are still many political prisoners in Burma, but we at least can take pleasure in knowing that one has been released.
21. One –In a triumphant video introduction Aung San Suu Kyi thanked the crowd for their activism, and reminded us that like us, she is a U2 fan.
22. Where The Streets Have No Name –I am not alone in wanting more of Bono's beautiful intro of Hallelujah to Streets. Written by Montreal native son, Leonard Cohen, Hallelujah embodies the wonderful combination that U2 means to me: joy, hope, and yet a longing for more.
The band leaves the stage and a brief video of aliens and spaceships took us into the encore.
23. Ultra Violet (Light My Way) –This is one of my favorite U2 songs and certainly my favorite from Achtung Baby. The crowd was receptive, but didn't seem to fully know what to do with it because Ultra Violet was not a big hit or a single from the band. I don't care and thoroughly enjoyed it. I don't mind being selfish for a moment in a crowd of 80,000.
24. With Or Without You –This is a closing favorite with so many U2 fans. I don't know if Bono and the guys would get out of the stadium alive if they neglected to play it. As if he knew this, Bono added the special lyrics of "We'll shine like stars in the summer night! We'll shine like stars, it'll be alright!" to the end of it.
25. Moment Of Surrender –What is surely the best version I have heard of this song closed out the night.
I enjoyed my time in Montreal, and sharing U2 with its people will be a great memory for life. I am fortunate to get to travel to see the band. I take this for granted sometimes. Meeting friends that I have chatted with online for weeks (or even years) at shows is a special thing. Seeing a U2 show with them and with new people that I meet is a great experience, especially when some are seeing the band for their first time. Hallelujah, Montreal. Merci.
Review, pictures and videos by kramwest1


text:
Mary Rose CardenasFormer Trustee and Chair, Texas Southmost College DistrictCo-Owner and Vice President, Cardenas Motors & Cardenas Development
"My Husband claims that I spent most of my time thinking about the college, talking to people about the college, or thinking for the college and he's right. Because, since the beginning, I have known that Texas Southmost College was this community's greatest asset."
Mary Rose Cardenas attended classes in the 1940s when TSC was known as Brownsville Junior College. She was forced to withdraw at the insistence of her "very old-fashioned" father, who was concerned about the number of GIs returning to the college after WWII.
Dreams of college were left behind permanently at age 17, when Cardenas took over supporting the family after her father became ill.
As a young woman, then wife and mother, Cardenas worked as a bookkeeper and manager for several Brownsville businesses over the years. She also worked side-by-side with her husband who secured the city's first Buick franchise in 1971. Cardenas Motors now has dealerships in Brownsville and Harlingen and was cited by Hispanic Business Magazine as one of the nation's top Hispanic-owned corporations. She is Co-owner and Vice President of Cardenas Motors and Cardenas Development.
First elected to the TSC Board of Trustees in 1984, she was re-elected in 1990 and 1996. She served four terms as Chairman.
Under her leadership as chair, the college began its groundbreaking partnership with UT Brownsville, restored an historic campus, added new acreage and numerous state-of-the-art buildings, and launched an award-winning scholarship program that made higher education possible for thousands of talented students. Her energy and persistence are credited with bringing a full, four-year university to Brownsville many years sooner than UT officials had originally planned.
She has served her community on various boards including the Driscoll Children's Hospital, Valley Regional Medical Center, the Rio Grande Council of the Boy Scouts of America, and the Catholic Diocese of Brownsville. The recipient of numerous awards, most recently she received the prestigious Distinguished Service Award from the Association of Governing Boards of Universities and Colleges.
The University of Texas at Brownsville website uses Javascript.
To access this page as it is meant to function please use a Javascript
enabled browser.


text:
Top Definition
When a gay man has to schedule a time with his boyfriend to abuse his anus because the boyfriend is too busy getting his back blown out by the rest of the gay community.
Will had to schedule a stool conference with drunk Jeff the gay dentist because Jeff had too many patients to see.
av Wilma Fingerdoo 12. mai 2008
Trending Now
Can you define these popular missing words?


text:
See where Khloe Kardashian and Lamar Odom lived during their short stay in Dallas
Photo: Photo courtesy of Realtor.com
The couple's new posh condo at the W Dallas Victory Hotel & Residences features two bedrooms, two bathrooms and plenty of amenities.
To post a comment, log into your chosen social network and then add your comment below. Your comments are subject to our Terms of Service and the privacy policy and terms of service of your social network. If you do not want to comment with a social network, please consider writing a letter to the editor.


text:
Popovich had successful MLB career after WVU
April 13, 2013
MORGANTOWN — Did you ever hear of a Major League player with a perfect batting average of 1.000 for a season? Well, meet Paul Edward Popovich, a native of Flemington in Harrison County....
No comments posted for this article.
Post a Comment
You must first login before you can comment.


text:
Pursuant to Section 50.45.4 of the Beaverton Development Code, public notice of the following comprehensive plan amendment applications is being provided:
Comprehensive Plan Update—Chapter One:
City Goals CPA2012-0006
Comprehensive Plan Update—Chapter Two:
Civic Engagement CPA2012-0007
Comprehensive Plan Update—Chapter Thirteen: Amendment Procedures CPA2012-0010
The City of Beaverton is beginning a process to update the City's Comprehensive Plan to incorporate the results of the recently completed Community Visioning Project and Beaverton Civic Plan. As a part of this project, the City is reorganizing some Plan Elements and creating some new ones, such as Community Health and Sustainability. The first phase of the update project , which is the subject of this notice, includes the Introductory Chapter (Ch. 1), the Civic Engagement Chapter (Ch. 2), and the Chapter on Amendments to the Plan (Ch. 13). Chapter 1 will present the overarching goals and desired outcomes of the City, as identified through the Community Vision and Civic Plan. Chapter 2 will present a collection of public involvement tools and strategies. Chapter 13 will contain the procedures and criteria for making future amendments to the Comprehensive Plan. The proposed changes will apply City-wide.
To be addressed in the staff report, written comments on the above development proposal shall be submitted no later than 5:00 p.m. on Friday, January 4, 2013. Mailed written comments shall be sent to the Planning Division, PO Box 4755, Beaverton, OR 97076. Written comments submitted in person shall be delivered to the Planning Division, 2nd Floor, Beaverton City Hall, 4755 SW Griffith Drive.
The decision-making authority for the above applications is the Planning Commission, which will review the proposal in accordance with the approval criteria contained in Chapter One of the Comprehensive Plan and make a recommendation to the City Council. The Planning Commission is scheduled to hold a public hearing on the above applications on Wednesday, January 16, 2013, beginning at 6:30 p.m. The meeting will be held in City Council Chambers, 1st Floor, Beaverton City Hall, 4755 SW Griffith Drive.
Written comments or exhibits submitted prior to the hearing to be submitted by staff at the hearing must be received by the Director no later than 4:30 p.m. on the day of the scheduled hearing. All submittals that are more than two (2) letter size pages must include no fewer than ten (10) complete copies of the materials being submitted.
Copies of the staff report are available for inspection at the Community and Economic Development Department (CEDD) Planning Counter or may be purchased at reasonable cost or are available for on-line viewing at www.beavertonoregon.gov. Staff reports are published a minimum of seven (7) calendar days before the date of the initial public hearing.
Dated this 5th day of December, 2012
Steven A. Sparks, AICP, Planning Division Manager,
City of Beaverton
Publish 12/13/2012. VT8596


text:
E2E: Erik Meijer and Jeroen Frijters - IKVM.NET (Java VM implemented in .NET)
- Posted: May 01, 2012 at 5:00AM
- 5 comments
Loading user information from Channel 9
Something went wrong getting user information from Channel 9
Loading user information from MSDN
Something went wrong getting user information from MSDN
Loading Visual Studio Achievements
Something went wrong getting the Visual Studio Achievements
Right click "Save as…"
At Lang.NEXT 2012, several conversations happened in the "social room", which was right next to the room where sessions took place. Our dear friend, Erik Meijer, led many interesting conversations, some of which we are fortunate enough to have caught on camera for C9.
Here, Erik interviews fellow Dutchman Jeroen Frijters, the creator and maintainer of IKVM.NET. See Jeroens' Lang.NEXT 2012 IKVM.NET presentation.
IKVM.NET is an implementation of Java for Mono and the Microsoft .NET Framework. It contains a Java Virtual Machine implemented in .NET, a .NET implementation of the Java class libraries, tools that enable Java and .NET interoperability.
Tune in.
Thank you Erik and Jeroen for the excellent conversation.
Oops, something didn't work.
IKVM is always a hero project, outstanding work !
Does the CLR team provide help for Joroens ?
Take a look at these:
it's creating a buzz!
Very interesting project. I can see a lot of uses for it. Good luck.
The guy is called Jeroen, not Jeroens, presumably because there's only one of him.
@Erik Post: Oops
Comments have been closed since this content was published more than 30 days ago, but if you'd like to continue the conversation, please create a new thread in our Forums, or Contact Us and let us know.


text:
Meet hot Manchester lesbian personals at matchmaker personals. Our site has thousands of lesbian, gay women, bisexual, transgender and transsexual members. Looking for a same sex relationships and looking for women seeking women in Manchester then create a free profile today, it's easy!
ManchesterJoin Now Free!
Manchester | Manchester Girls | Manchester Men | Manchester Gay
Black Singles | Asian Singles | Latin Dating
Matchmaker is a free Manchester lesbian personals site for your local area. We have the hottest, attractive and available Manchester lesbian women on the Internet If you are a single lesbian women in Manchester and are looking for friendship, casual encounters or a serious relationship, create your free profile today!


text:
The Stetson softball team will face one its stiffest challenges of the season this weekend as the Hatters visit USC Upstate for a three-game Atlantic Sun Conference series at Cyrill Stadium in Spartanburg, S.C.
The Spartans (29-3) not only currently sit in first-place in the A-Sun with a 10-1 league record, but are receiving enough votes for a virtual #26 national ranking in both the USA Today/NFCA and the ESPN.com/USA Today Top 25 polls.
The Hatters (20-13, 3-6 A-Sun), however, do not have to look very far back to find a history of success playing against USC Upstate in Spartanburg. In 2010, after starting the year 1-4 in conference play, the Hatters blanked USC Upstate 1-0 behind a brilliant one-hit shutout by Amanda Lindsey. That win sparked a 15-2 stretch for Stetson that carried the Hatters deep into the conference tournament.
Last season the Hatters made two trips to Cyrill Stadium. In the regular season, Meredith Owen hit two home runs and Courtney Brandt added another as Stetson won 5-2 in game one of a doubleheader.
Then in the opening round of the Atlantic Sun tournament, Brandt fired a two-hit shutout as the Hatters claimed a 1-0 victory over the Spartans.
"This weekend is huge for our team," Brandt said. "USC Upstate is number one in our conference right now and if we have any hope of going to the tournament then we need really need these wins. I have all the confidence in the world that we can do it."
Demi Meza hit two home runs during last year's A-Sun tournament, including one against the Spartans in the 1-0 Stetson victory.
"Because we had the opportunity to play at Upstate twice last season, we definitely have the advantage of knowing the ins and outs of their field," Meza said. "Often times when we travel, we have a difficult time adjusting to other fields and atmospheres. That shouldn't be a huge issue this weekend."
Upstate enters the weekend red-hot, having won eight straight and 15 out of its last 16 games overall. The Spartans lead the conference in several offensive categories, including batting (.354), slugging (.544), on-base percentage (.403), and scoring (7.1). Five starters are batting over .350.
What will the Hatter pitchers need to do to be successful?
"We need to stay mentally tough against their hitters," Owen said. "If we get frustrated things will snowball, so if they start hitting we need to make fast adjustments to keep them off balance."
Stetson is coming off a 2-1 weekend against Northern Kentucky in which Brandt went 2-0 in the circle and Jessica Griffin hit a walk-off single in the bottom of the eighth inning on Saturday. Owen also went deep for Stetson, giving her four home runs against A-Sun opponents this year.
"This weekend is very important for our confidence as well as our conference standing," Owen said. "We need to go in with a confident and strong mindset that we can and will take these games."
At 3-6, the Hatters currently sit in eighth place in the Atlantic Sun. Only the top six teams qualify for the A-Sun tournament.
"This weekend is extremely important for us," Meza said. "We have all been working really hard during practice and coming closer together. Pulling out wins this weekend will help us get closer to our goal of making the conference tournament."
All three games this weekend will be broadcast by USC Upstate for free on ASun.TV. Saturday's doubleheader will begin at 4 p.m. while Sunday's series finale will start at 1 p.m. Fans can also get in-game updates by following Stetson Softball on twitter or by subscribing to the Hat-Alerts text messaging service.


text:
Pittsburgh International Festival of FirstsFeaturing the US debut of Florentijn Hofman's sensational 40-foot high Rubber Duck, the Festival of Firsts will present performance and visual art premieres by Companie Marie Chouinard, NanoDanses, Robin Frohardt, Perth Theater Company, Zimmerman & De Perot, 2b theatre company, Christopher McElroen & T. Ryder Smith, and Kurt Hentschlager.09/27/2013 - 10/26/2013Location: various locationswebsite
Once Upon a Time GalaCellist Yo-Yo Ma performs Tchaikovsky's "Variations on a Rococo Theme" with Music Director Manfred Honeck and the PSO in a gala concert that also includes Dvorak's Carnival Overture and music inspired by fairy tales. Premium tickets include a season-opening soiree at the Fairmont Pittsburgh with PSO musicians. 09/27/2013Time: 7:30 pmHeinz Hall, 600 Penn Ave., Pittsburgh, PAwebsite | map
Soldier's HeartBefore heading off to war in Iraq, Casey Johnson neatly organizes her life into a box of lists, envelopes and registration forms for her son's activities. Months later, she returns to Western Pennsylvania forever changed, with deep psychological scars that no amount of arranging seems to be able to fix. Directed by John Amplas for its world premiere, Tammy Ryan's poignant Soldier's Heart shines a light on the struggles facing women warriors.09/27/2013 - 10/13/2013Pittsburgh Playhouse, 222 Craft Avenue Pittsburgh, PAwebsite | map
Gallery Crawl with The Rubber DuckThis crawl celebrates the opening night of the Pittsburgh International Festival of Firsts, a project of Pittsburgh Cultural Trust. To mark the occasion, The Rubber Duck, the US debut of artist Florentijn Hofman's four-story-high rubber duck, launches into the Allegheny River, coming to rest by the 6th Street Bridge. The bridge will be closed to traffic to host The Rubber Duck Bridge Party featuring Night Market VI.09/27/2013Time: 5:30 – 10:00 pmLocation: Cultural District, Pittsburgh, PAwebsite
Ahmad JamalNoted for his outstanding technical command and identifiable sound as a piano stylist and composer, Ahmad Jamal needs no introduction in his home city of Pittsburgh. Jamal will present a concert of his latest works and classic tunes. He continues performing around the world, as he has for over four decades.09/27/2013Time: 8:00 pm1815 Metropolitan St, Pittsburgh, PAwebsite | map
Mayhem and MajestyMayhem and Majesty returns home to Pittsburgh, before its 3-week, off-Broadway run this winter. The show has wowed audiences around the country with its daring musical athleticism and visual exploits. Come join the Squonkers in preparing the Mayhem AND the Majesty to deliver to New York City.09/27/2013 - 09/29/201309/27 - 8:00 pm09/28 - 8:00 pm09/28 - 2:00 pm09/29 - 2:00 pmLocation: New Hazlett Theater, Allegheny Square East, Pittsburgh, PAwebsite
Granular SynthesisThe Austrian audiovisual media duo of Kurt Hentschlager and Ulf Langheinrich created large scale installations that fuse light and sound into one medium. Through their manipulation of technology, the works of Granular Synthesis serve to challenge human perception, conditioning and consciousness.09/27/2013 - 10/20/2013601 Wood St, Pittsburgh, PAwebsite | map
Carnegie Mellon University Wind EnsembleGeorge Vosburgh, Thomas Thompson, and Stephen Story conduct the Carnegie Mellon Wind Ensemble in a multitude of pieces including Gordon Jacob's Old Wine in New Bottles, Poulenc's Suite Francaise, Stravinsky's Symphonies of Wind Instruments, Holst's English Folk Song Suite, and Strauss' Serenade for 13 Winds. Free admission.09/28/2013Time: 4:00 pmLocation: Kresge Theatre, College of Fine Arts, Carnegie Mellon University, Pittsaburgh, PAwebsite
Compaignie Marie ChouinardMarie Chouinard creates dance conceived from primeval dreams— earthy and strong, yet shaped by irrepressible secrets and unseen dimensions in time. Selected to launch the Pittsburgh Cultural Trust's Pittsburgh International Festival of Firsts, the program will include Michaux Mouvements, inspired by poetry and drawings by Belgian artist Henri Michaux, and the U.S. premiere of Gymnopedies, set to piano pieces of Eric Satie. In Michaux Mouvements, the dancers form a stunning silhouette to projections exuding a haunting sense that they, in the artist's words, are connected to "the strangeness of natural things and the naturalness of strange things." This performance contains nudity.09/28/2013Time: 8:00 pmByham Theater, 101 6th St., Pittsburgh, PAwebsite | map
Party w/Ahmad Jamal and the Pittsburgh Jazz LegendsDetails and reservations online.09/28/2013Time: 8:00 pm1815 Metropolitan St, Pittsburgh, PAwebsite | map
Board of Directors
WQED Management
WQED History
Driving Directions
The Studio on Fifth
WQED MultimediaStrategic Plan 2013-2018
WQED FCC Public File
Privacy Policy
Accessibility Information
Diversity Statement
Local Content & Service Report
WQED: The Create Channel 13.2
WQED: The Showcase Channel 13.4
Pittsburgh 360°
Filmmaker's Corner
QED Cooks
Rick Sebak Documentaries
Contact Us
Facility Rentals
Email this page
Make a Donation
Special Gifts
Corporate Giving
WQED Presents Club
Other Ways to Give
Planned Giving
© 2016 WQED Multimedia | All rights reserved
Follow @WQED
Programs produced by WQED Multimedia for broadcast by others comply with the captioning quality standards embodied in Section
79.1(j)(2) of the rules of the Federal Communications Commission.
Mail filtering provided by www.mxguarddog.com


text:
Cast Iron Garlic Roaster
This item is currently not available.
Additional Information
The Easiest Way to Make Gourmet, Fire-Roasted Garlic
- Make your own savory roasted garlic
- Versatile cast iron roaster may be used on a grill or in the oven
- Use the silicone squeezer to extract garlic paste after roasting
On the grill or in the oven, this cast iron roaster transforms a head of garlic into a fragrant, savory-sweet paste that's ready for spreading on crusty bread, tossing with pasta or kicking up the flavor of soups and casseroles. Includes a 5-1/2" diameter cast iron roaster and silicone insert that makes it easy to squeeze out the garlic paste after roasting.
Product Details
- Cast iron, silicone
- Roaster is 5-1/2" in diameter x 5-1/2" H overall
- Silicone insert is 3-1/2" in diameter x 2" H
- Holds one large or two medium heads of garlic
There are no special shipping restrictions or charges associated with this item. For detailed information about our delivery methods and charges, click here.
We're proud of the fact that this item is shipped to you directly from our warehouse in Vermont, by one of our 250 employee-owners. In-stock items are packed with care and shipped within the next business day to ensure prompt delivery to your home and garden!


text:
Muscle Shoals Booty CallHome > Alabama > Muscle Shoals
I've travelled a lot, and if there's one thing you always hear, its how many crazy horny people there are in Muscle Shoals, just getting it on left and right, casual sex with strangers, all kinds of Austin Powers wierd shagging. It must be something in the water, because everyone I know calls it "Booty Call Muscle Shoals" there's so much horniness in the air. Apparently you can just walk down the street and trip over a new booty call. Must be nice :)


text:
Actor Steven Seagal was sworn in as a Dona Ana County Sheriff's deputy on Tuesday morning.
Undersheriff Eddie Lerma arranged to have Seagal sworn-in as a deputy in Doña Ana County as part of future training on border issues, and to execute police work if necessary.
Sheriff Todd Garrison read Seagal his oath during a brief, informal ceremony at the Doña Ana County Sheriff's Department main headquarters. Seagal asked that no pictures or video be taken of the ceremony, according to sheriff's officials.
"Mr. Seagal has spent decades in law enforcement training, and has a special interest in the unique challenges our department faces along the border," said Lerma. "He has been an asset to other border communities, where he believes public safety is of particular concern. We are honored to bring that experience to this department as well."
Seagal has 25 years of experience in law enforcement and holds credentials in several border communities, including Hudspeth County, Texas and Maricopa County, Arizona
Seagal currently stars in the Reelz TV drama "True Justice" about an undercover police team in Seattle. Seagal plays Elijah Kane. Seagal also has starred in reality shows about law enforcement.


text:
Systemwide Events Calendar
|Saturday, April 5
|Student Organic Farm Training (SOFT) Farm Workday
Manoa Campus, Magoon Research Station
|Paliku Arts Festival
Windward Campus, Paliku Theatre plaza and Hale Palanakila art spaces
|Stand and Deliver: Presenting For College Classes
Maui Campus, The Learning Center
|A Movie Under the Stars
Honolulu Campus, Campus Lawn
|Rupert Boyd, guitar
Manoa Campus, Orvis Auditorium
- Highlighted dates have scheduled events.
- Select the date to view all events for that day.
Ongoing Events
- Our Musical Heritage: The Royal Hawaiian Band
- Na Pa'i Ki'i o Brother Bertram
- A World of Chinese Puppets from the Lin Liu-Hsin Museum, Taiwan
- i.KEA Inspiring Knowledge, Empowerment and Achievement
- TRIO-SSS Summer Bridge 2014
- Waikiki Parc Features Tonia Moreno
- YUAN: by Beili Liu
- Windward CC Art Faculty Exhibit at Gallery 'Iolani
- Traveling Exhibit: Gardens of Hawaii
- Book Making in the 18th Century: In Diderot's Encyclopedie, 1751-1780
- HI Pride T-Shirt Contest
- Candidates for ASUHWO Student Government
- Go for Broke: Japanese American Soldiers Fighting on Two Fronts
- "ART 336—Wearable Art" by Madeleine Soder's students


text:
Originally Posted by
The Detroit Red Wings will announce a two-year extension for forward Todd Bertuzzi as early as Thursday,
Bertuzzi's agent, Pat Morris, told the Free Press today that "we're working at it, and getting closer." The sides have been talking for the past month.
Bertuzzi, 37, is in the last of a two-year deal that's averaged $1,937,500. His new deal is for closer to $2.2 million a season, and is backloaded.
General manager Ken Holland told the Free Press last month that "I think Bert's been great all season." The Wings like how Bertuzzi has developed into a two-way player, and how he helped get the first line going after being put with Pavel Datsyuk and Johan Franzen on Nov. 17, in the game against Los Angeles. Bertuzzi has 12 goals and is plus-21 in 54 games this season.
The Wings first acquired Bertuzzi in March of '07 at the trade deadline. He signed with Anaheim that summer after becoming an unrestricted free agent, but came back to Detroit two years later. The Wings like the size he brings (6-foot3, 200-plus pounds) and that he's accepted being a net-front guy and integrating defensive hockey into his game.
"He's embraced everything we're about," Holland said.
Edit: Bad link fixed
Edited by Crashnburnluder, 22 February 2012 - 09:47 AM.


text:
Top Definition
Dopeman is one of the most famed game "rippers" of all time.
This entity creates popular titles and uploads them so all the downloader must do is simply unpack them, and play.
This entity creates popular titles and uploads them so all the downloader must do is simply unpack them, and play.
"How'd you get that new game, Portal, for free?!"
"I got it from dopeman!"
"I got it from dopeman!"
po idiotsoftcorp Децембар 27, 2007
Trending Now
Can you define these popular missing words?
A dope dealer. This can be crack,weed, or anything in between.
You need a nigga wit' money so you get a dope man.
po nokianinja Октобар 7, 2002
A slang term for a drug dealer who sells mutuple drugs. for more see the word " Dope "
Where's the dope man at?
po 187 Април 5, 2003
The classic Nike Cortez, worn best with fat laces.
Original Gangsta kicks, see also Chucks
Original Gangsta kicks, see also Chucks
The new J's are ugly and cost too much, but the Dopemans will always be hard!"
po JGSR Новембар 16, 2007
Seller of narcotics
"If you see somebody getting pussy for crack, he's the dopeman, dopeman" -- N.W.A.
po ac Јануар 31, 2004
Michigan term used only for Nike brand Cortez street shoes.
Look at those new black and gray Dopemans!
po Direcca McFadden Март 7, 2006
Alias Ricky. Has so much dope in his system he is immune to all effects of tranquilizing darts.
It's Dopeman! He can smoke a pound in a single bound.
po Stephen French Јун 30, 2009


text:
Auburn Boulevard may get long-awaited makeover
Next video starts in : 7 Play
Auburn Boulevard may get long-awaited makeover
Several injured in shooting near Houston shopping center
1:37Now watching Up next
Auburn Boulevard may get long-awaited makeover
Sacramento residents around Auburn Boulevard hope the addition of a new Niello mini-dealership with help further efforts to clean up the neighborhood.
0:46Now watching Up next
Several injured in shooting near Houston shopping center
On Monday, several morning commuters in Houston were injured after a suspect fired 20 to 30 shots near an upscale shopping center. Acting Houston Police Chief Martha Montalvo said, "The individual was firing actively at the officers, at which time the officers engaged the individual. The suspect was pronounced dead soon after."
1:02Now watching Up next
Wake Forest Honors Alumnus Arnold Palmer
Arnold Palmer played golf at Wake Forest College when the school was actually still in the North Carolina town that bears its name. On Monday, the college's birthplace museum was draped in black crepe in honor of its famous alumnus. (Sep. 26)
1:13Now watching Up next
Worst Advice: Jay Sean
Singer/Songwriter Jay Sean shares the worst piece of advice he's received throughout his career, with Rebecca Jarvis.
1:39Now watching Up next
Tim Burton's peculiar powers
Director Tim Burton and the stars of "Miss Peregrine's Home for Peculiar Children"discuss what special powers they would like to have (Sept. 26)
1:23Now watching Up next
Stone unveils 'Snowden' in Switzerland
Director Oliver Stone was joined by "Snowden" stars Joseph Gordon-Levitt and Shailene Woodley as he premiered his latest movie at the Zurich Film Festival. (Sept. 26)
1:46Now watching Up next
Tim Burton's lightbulb moments
Stars of new fantasy adaptation, "Miss Peregrine's Home for Peculiar Children," Eva Green, Asa Butterfield and Ella Purnell discuss what it's like to work on a Tim Burton set. (Sept. 26)
1:58Now watching Up next
Bomb Case is Latest Hardship for NJ's Muslims
The case of the New Jersey Muslim man charged with planting bombs in New York and New Jersey is the latest of many challenging moments for the state's large Muslim population. They will soon get their say at the ballot box. (Sept. 26)
0:44Now watching Up next
Australian Teen Surfer Stable after Shark Attack
A teenage surfer was in stable condition after he was bitten by a shark on Monday at the same Australian beach where a Japanese surfer was fatally attacked last year, officials said. (Sep. 26)
1:59Now watching Up next
Raw: Syrian Red Crescent Delivers Aid, Supplies
The pro-government Syrian Central Military Media has released footage of Syrian Red Crescent vehicles heading to Zabadani and Madaya in the west of Syria near the Lebanese border. (Sept. 26)


text:
Ordained at Hebrew Union College-Jewish Institute of Religion (HUC-JIR) in 1983, Myers was appointed the first female rabbi to lead a congregation in Southern California three years later at the age of 29. She retired in 2001 to be a full-time mother to her two children.
"I came to understand that for me, congregational life, which I love and have cherished for these 18 years, is incompatible with raising children and having a reasonable home life," she told The Journal in June 2001.
She continued to serve on the board of the Reform movement's Central Conference of American Rabbis, developing curricula for HUC-JIR, and presiding at marriages and bar and bat mitzvahs.
"Here she will be missed greatly," said Rabbi Rick Schechter, the third spiritual leader of Temple Sinai since Meyers. "She was a brilliant woman and gave so much to the community."
During Meyers tenure, the membership of the synagogue doubled to 300 member families.
Rep. Adam Schiff (D-Pasadena), who has been a Temple Sinai member for more than a decade, described the rabbi as "warm, affectionate and down-to-earth," and said her sermons "packed the synagogue." In November 2001, he invited her to deliver a prayer at his inauguration.
"It was so uplifting and life-affirming," he said of the post-Sept. 11 prayer about all the places you could see the existence of God. "She was trying to console a nation," he said. "I know members of our community are asking now, 'How does any of this make sense? How can it be?'" Schiff said, and suggested Meyers own words then could respond:
"Eternal God, be with us as we move through this time of uncertainty," Meyers had said. "Help us know that we can lend Your presence and use our lives to reflect it. Then we will have the faith to bring light and joy, peace and comfort, justice and goodness to this magnificent world God has created. Amen."Rabbi Meyers is survived by husband, U.S. Magistrate Judge Ralph Zarefsky; and sons Joe, 14, and Gus, 10.
Services will be at 10 a.m. Tuesday at Mt. Sinai Memorial Park, 5950 Forest Lawn Drive, Los Angeles.
-- Amy Klein, Religion Editor
View our privacy policy and terms of service.


text:
Cheryl Walker, Culpeper resident and friend of Today's Country 103.1 WJMA has once again let us post some of her photos from area concerts. Check back often for more photos from Today's Country Superstars!!
*(C)Photos may not be re-posted or duplicated without written permission first.
Brad Paisley/Blake Shelton/Jerrod Niemann- H2O World Tour- Jiffy Lube Live 9/24/11
Janedear Girls (Side Stage openers with Eden's Edge)
Jerrod Niemann opens for Brad & Blake
Blake Shelton & Band
Blake Shelton
Brad Paisley
Brad Paisley
Brad Paisley at Jiffy Lube Live
Blake Shelton returns to the stage to sing with Brad
Brad sings to the crowd at the back of the pavilion and those on the lawn
Thank you....Goodnight!!
Rodney Atkins- Celebrate Virginia Live, Fredericksburg, VA- Friday, Sept. 9th
Rodney Atkins in Fredericksburg, VA
Rodney Atkins at Celebrate Virginia Live in Central Park (Fredericksburg)
Rodney Atkins in Fredericksburg, VA Sept. 9th 2011
Rodney Atkins performs live in Fredericksburg, VA
Shenandoah County Fair- Joe Diffie, Sammy Kershaw & Aaron Tippin, Sept. 1st
Aaron Tippin, Sammy Kershaw & Joe Diffie (The Roots & Boots Show)
Joe Diffie
Sammy Kershaw
Aaron, Sammy & Joe (The Roots & Boots Show)
Aaron Tippin
American Idols Live Tour 2001- Verizon Center, Washington D.C.- 8/19/11
American Idol Live Tour 2011
Lauren & Scotty
Chris Young- Rockingham County Fair 8/18/11
Chris Young
Chris Young
Chris Young
Chris Young
Tim McGraw/Luke Bryan & The Band Perry- Jiffy Lube Live, Bristow, VA 8/13/11
The Band Perry
The Band Perry
Luke Bryan
Luke Bryan
Tim McGraw
Tim McGraw
Luke Bryan & Tim McGraw
Keith Urban & Jake Owen- Verizon Center, Washington D.C. 7/28/11
Jake Owen
Keith Urban
Keith Urban
Keith Urban
"FlattsFest 2011" W/Rascal Flatts/Sara Evans/Justin Moore/Easton Corbin- Jiffy Lube Live 6/18/11
Justin Moore
Justin Moore
Easton Corbin
Easton Corbin
Sara Evans
Sara Evans
Rascal Flatts
Rascal Flatts
Rascal Flatts
Sara Evans joins Rascal Flatts on Stage
Sugarland & Little Big Town- Columbia, MD 5/22/11
Little Big Town
Little Big Town
Little Big Town
Sugarland & Little Big Town
Jason Aldean/Eric Church/JaneDear Girls- JPJ- Charlottesville 3/3/11
Eric Church
Eric Church
JaneDear Girls
Jason Aldean
Jason Aldean & the crowd at JPJ Arena
Jason Aldean W/Kelly Clarkson via video magic


text:
Share |
HIGH SCHOOL: Was a four-year letter winner in cross country and track and field at St. Joseph Academy in St. Augustine, Fla. … Was named the school Female Athlete of the Year in 2009 ... Was an honor roll student and a member of the Hispanic National Honor Society ... Was active on the student council.
PERSONAL: Full name is Kristina Emilia Cicchetti … Was born on July 10, 1991, in Mount Vernon, NY … Parents are Marina and Richard Cicchetti … Has one sister, Claudia Spengler (37) … Is a Biology major.
HOBBIES: Reading, cooking and running.


text:
But now I go and out him here. Ah well. We can laugh about it now. But I still sometimes cry about it inside.
Today's song was a tribute to what is in my blood, and now Ivy's. She's a true mountain girl.
That'll make a tadpole slap a whale... I think this means something is really good. He's always saying he's busy stacking bbs or he's gonna take his marbles and go home.
Growing up we'd visit family in West Virginia and there was always a new cousin to meet that I'd never known about, and sometimes maybe even a new aunt popping up that no one had known about and it smelled there. Always felt old and like we were going back in time. Back then I just didn't understand that to my family, that was home.
Poppal's always called me his Ceedy Kooker. I don't know what that is, but it makes me feel special.


text:
A gun story with something for everybody
March 21, 2013 - Harry Eagar
First, if you haven't already, you have to read the complete story. A lede graf doesn't quite convey all the sides of this gun story:
"About 12:20 p.m. Wednesday, a woman was in her Ellis County, Texas, home when she heard someone try to open the back door. She contacted her husband, who was in the area. The husband drew a gun on the robbers, who ran from the home, firing as they went, said Jo Ann Livingston, spokeswoman for the Ellis County sheriff's office in Texas.
"Although the husband hit one of the robbers, he apparently died from a self-inflicted wound in an adjacent field. The other robber was found in the pickup stolen in Oklahoma, also dead by his own hand."
So, 2 more firearms deaths in the heartland of gun country. But how are the statisticians to allocate these?
Do we score 2 for armed citizen defending his home?
Or do we score 2 for if you keep firearms at home, the person most likely to get shot is a member of your household?
Or do we assign these 2 deaths to the majority of firearms deaths that are suicides?
Do we score 2 for children shot to death?
Other thoughts obtrude.
The Oklahoma family had (at least) 17 firearms. In a nation with only one gun per person, they were hogging the supply. With about 500% of their share, they were depriving at least a dozen other Americans of the chance to have an event like this at their own homes.
I bet there were at least 17 Bibles in that house. (Personal note: there are about 17 printed bibles in my house, if you count indexes and concordances; and hundreds in translation on a Bible app on my iPhone. But no guns.)
The perp was home schooled. Dunno if that included firearms safety and responsibility.
In the comments on an early story about this incident, a reader opined that she imagined the father would now rather have his son back than all those guns. But she was not from Oklahoma. The father was remarkably (to any non-Oklahoman) casual about it:
"My biggest thing is the family down there and what they're going through. ... I would have done the exact same thing as the homeowner. My heart goes out to them," Roland Chaffin said.
That's how they roll in Oklahoma.
Article Comments
No comments posted for this article.
Post a Comment
You must first login before you can comment.
Blog Links


text:
WASHINGTON, DC , June 18, 2015 (Press Release) -
The American Forest & Paper Association released its May 2015 U.S. Paperboard Report.Read more
OFFENBACH am MAIN, Germany, June 15, 2015 (Press Release) -Established in early 2004, Tianjin Mohi Paper Printing Co., Ltd. is a large-scale packaging printer specializing in corrugated cardboard as well as middle- and high-end paper boxes in North China. With an annual turnover of RMB 1 billion, the group has more than 1,500 high-qualified staff members in its six major production facilities in the area surrounding Bohai Sea.Read more
SAO PAULO, June 18, 2015 (RISI) - Carton packaging supplier SIG Combibloc has announced a Real 221 million ($70 million) investment to expand its production capacity by 40% at its Campo Largo plant, Paraná state, southern Brazil. The unit currently produces 3.2 billion packs per year, and after the expansion the annual output will hit 4.5 billion units.Read more
PARSIPPANY, NJ, June 18, 2015 (Press Release) - Sun Chemical introduced its new SunSys resistance coatings, a series of water-based coatings formulated to impart or enhance resistance properties to paper and board substrates while at the same time being FDA compliant for direct food contact.Read more
DALLAS, June 10, 2015 (Press Release) -To maintain its fast growth and to offer maximum flexibility to its customers, a new KBA-Flexotecnica EVO XD eight-color flexo press will be delivered to Seydaco Packaging Corp., an innovative packaging firm located in Mississauga, Canada, later this year.Read more
KINGSEY FALLS, QC, June 18, 2015 (CNW) -Cascades, a leader in the recovery and the manufacturing of green packaging and tissue paper products, is pleased to announce that its line of UltratillTM products was selected by the Canadian Plastics Industry Association as the recipient of the CPIA Sustainability Award. This prestigious award was accepted by Mathieu Roberge , Products and Processes Development Manager at Cascades, during the CPIA Plastics Industry Leadership Awards Dinner held in Toronto on June 15 th.Read more
ROCHESTER, NY , June 16, 2015 (Press Release) -Diamond Packaging won five awards in the 22nd Annual FSEA Gold Leaf Awards Competition, the industry's premier showcase for foil stamping, embossing, and other specialty effects. Awards were announced at the FSEA/IADD Odyssey in Schaumburg, IL on May 14, 2015.Read more
HELSINKI, June 22, 2015 (Globe Newswire) - Stora Enso plans to permanently shut down the Group's corrugated packaging converting unit in Chennai, India, due to unprofitability and a major decrease in local market demand.
The mill closure will involve negotiations with the local employees' union. The mill employs 350 people, who will receive compensation and other support including training, medical care and assistance in finding new employment.Read more


text:
Mane and Tail Brush
Make your horse's tail look full and silky with the Mane and Tail Brush. Read more...
The Mane/Tail Brush detangles your horse's mane and tail.
100% Satisfaction Guaranteed - Your Money Back Any Time, for Any Reason.
Smith Brothers is proud to offer a 100% satisfaction guarantee on all of our products. We stand behind the quality of our products, and should you not be satisfied with your purchase, simply return it and we will refund, replace or exchange it for you.


text:
Source: Microsoft
quote: And then ignore Metro. For eternity.
quote: Now you'll get folks trying to open a pdf and they're taken to some weird full screen program, or they try to open a picture and again are taken to some metro app, and they'll think, "What is this? How did I get here?" And most damning of all, "How do I get out and back to what I'm familiar with?" After a time they'll figure out how to open pdf's in Reader on the desktop, and how to view pictures in a window,
quote: Well, that's a bad sign. I installed 8 in March on my test rig, and at my wife's request removed it last week to put 7 back on. Why would she or anyone else want to learn this stuff when it isn't an improvement? Because it's new and different?


text:
NSCLC is "Major Battlefield" as Merck,...
As Immunotherapy Revolutionizes the Cancer Treatment...
Expanding Use of NGS Has Largely...
Developers of DTC Genetic Testing Are...
Seattle retains option to co-develop resulting anticancer candidates at end of Phase I development.[Sebastian Kaulitzki-Fotolia.com]
Genmab has signed a second antibody-drug conjugate (ADC) research collaboration with Seattle Genetics. The new agreement gives the Danish firm rights to use Seattle's ADC technology in combination with a preclinical antibody candidate, HuMax-CD74, which targets CD74 expressed on a range of hematological and solid cancer cells.
Under terms of the new deal Genmab will be responsible for research, manufacturing, preclinical development, and Phase I clinical evaluation of ADCs under the collaboration. Seattle will receive an up-front payment and funding for research support provided to Genmab. Seattle in addition has the right to exercise a co-development and co-commercialization option for any resulting ADC products at the end of Phase I clinical development. If the firm does opt into an ADC program it will make a payment to Genmab and the firms will then share all future costs and profits on a 50:50 basis. If Seattle decides not to opt in to any ADC products, it will receive a payment from Genmab and additional milestones and mid-single-digit royalties on future worldwide net product sales.
Seattle and Genmab signed their initial ADC collaboration in December 2010. Under terms of this deal Genmab is using Seattle's ADC technology in combination with its own HuMax-TF antibody that targets the tumor-expressed tissue factor (TF) antigen.
Seattle's ADC technology is designed to target monoclonal antibody-drug conjugates specifically to tumor cells. The platform uses synthetic cytotoxic auristatins and stable linker systems that attach auristatin to the antibody. The linker systems are designed to be stable in the bloodstream and only release the cell-killing agent once inside targeted cancer cells.
Seattle's own lead, registrational-stage candidate, brentuximab vedotin (SGN-35), is being developed in partnership with Millennium. The CD30-targeting ADC was submitted to FDA for approval in February as a treatment for both relapsed or refractory Hodgkin lymphoma, and relapsed or refractory systemic anaplastic large cell lymphoma. A Phase III trial is separately evaluating brentuximab vedotin for the prevention of post-transplant Hodgkin lymphoma relapse. The ADC is also being assessed in a Phase II study for the retreatment of Hodgkin lymphoma and systemic anaplastic large cell lymphoma, and Phase I trials as front-line therapy for both cancers, in combination with chemotherapy. Under terms of the deal with Millennium Seattle retains full commercialization rights to brentuximab vedotin in the U.S. and Canada, while its partner has exclusive rights to commercialize the product in all other countries. Seattle says Millennium plans a first half 2011 marketing authorization submission to the European regulators.
Seattle's early clinical-stage pipeline includes ADC candidates against renal cell carcinoma, pancreatic and prostate cancers, and CD19+ hematologic malignancies, together with engineered monoclonal antibodies targeting non-Hodgkin lymphoma, multiple myeloma, and autoimmune diseases.
To save this item to your Favorites,
log into GEN Select.
We'll be sure to take you back here after you do.
Not a member of GEN Select?
To comment on this article,
log into GEN Select.
We'll be sure to take you back here after you do.
Join 110,000 colleagues who rely on GEN Highlights for breaking news and exclusive articles shaping today's life science tools and technologies.
You're all set! Thank you for subscribing to GEN Highlights.
Novum Pharma recently raised the price of an acne cream by over 3,900% in less than a year-and-a-half and Mylan increased price of EpiPen from $100 to $608 . Do you think pharmaceutical companies need to be subjected to price controls?
Be sure to add [email protected]
to your Address Book or Safe Senders List.
here for instructions.
If you have any questions about your subscription, click
here to email us or call at (914) 740-2189.
You may also be interested in subscribing to the GEN magazine, an indispensable
resource for everyone involved in the business of translating discoveries at the
bench into solutions that fight disease and improve health, agriculture, and the
environment. Subscribe
today to see why over 60,000 biotech professionals read GEN to
keep current in the areas of genomics, proteomics, drug discovery, biomarker discovery,
bioprocessing, molecular diagnostics, collaborations, biotech business trends, and
© 2016 Genetic Engineering & Biotechnology News All Rights Reserved


text:
White-collar conundrum
Prof. Sam Buell discusses his new book on the rise of criminal behavior in corporations and why it's so difficult to prosecute.
The Duke way
» Public service is a core value of the legal profession and central to the Duke Law experience.
Emerging tools for more equitable policy
» Professor Matthew Adler co-edited the new Oxford Handbook of Well-Being and Public Policy.
Welcome Back Reception
Recent News
- Jonathan Wiener addresses climate, catastrophes, retrospective review, TTIP, and China's environmental risk regulation
- Aronie '93: Combat professional atrophy by doing something "new, different, and even scary" The Federal Lawyer
- Purdy discusses faux chivalry, transgender identity, and college basketball The New Yorker


text:
shoppers recently viewed this!
Steiff Club Teddy Bear Annual Edition 2010
- Color:
- cream
Qty: 1
- 1
- 2
Description: This 12 inch tall, fully jointed Teddy bear is crafted from cream-colored mohair. He is wearing a lavender ribbon embroidered with gold colored thread which identifies him as the Steiff Club Edition 2010. Authorized Steiff Club retailers can "stock" the Club Edition Bear so Club members can see the actual bear before buying him and may purchase as many of this bear as they wish. Each piece has a gold plated "Button in Ear" and a consecutively numbered ear tag with red Steiff logo.
- Made of the finest mohair and stuffed with synthetic filling material
- 5-way jointed
- Safety eyes
- Famous Steiff 'Button in Ear' ear tag
- Measures 11.81"
- Spot clean
- Age 4 year and up
Material: Mohair
Care: Spot clean
Brand: Steiff
Origin: Germany


text:
What Worms Could Be Doing To Your Dog
We know that a dog can be your best friend. The problem is that your best friend can't tell you when it has a problem. It is not pleasant to think about, but worms in dogs can be a common problem. Unfortunately, there's no way your dog can tell you that there are worms busily at work in its intestines – maybe even sucking its blood.
The Mistake People Make
Most dog owners make one big mistake about dogs and worms. They don't pay enough attention to the dog's stool. Well, okay, keeping a close eye on your dog's poop is not the most fun thing in the world. But it's the best way to see if your dog has a worm problem.
What You Might See
If you pay close attention to your dog's stool, you might see tiny, white things moving around in it – which is a sign that you dog probably has a tapeworm. Those white specs that look a lot like grains of rice are actually cast off tapeworm segments. You might also see some of them around your dog's anus.
A Dark, Tarry Looking Stool
Is your dog's stool dark and tarry looking? In this case, it may have a hookworm infection. These nasty, little creatures fasten themselves to the walls of your dog's intestines and actually suck its blood. One hundred adult hookworms can drain about 10% of your dog's blood every day.
Is there something in the dog's stool that looks like overcooked spaghetti?
If you see something in your dog's poop that looks a bit like overcooked spaghetti, the dog may be suffering from a roundworm infection. These parasites – which can be as long as 7" – may also cause the dog to suffer diarrhea or constipation.
Another Vampire Worm
Another type of dog worm that will suck your dog's blood is whipworms. They are 2" to 3" long, thin and whip shaped – hence the name whipworms. If your dog becomes infected with enough of these worms, it can suffer internal hemorrhages. If this were the case, you would most likely see blood in its stool.
Another Type Of Worm That Could Kill Your Dog
While you can see that your dog may have whipworms, hookworms, roundworms or tapeworms by watching its stool, there is one type of worm that cannot be seen in the dog's poop.
This worm is the heartworm. It is not only far more serious than these other worms, it is harder to spot – because heartworms will usually cause no visible symptoms until they are clogging your dog's lungs and heart. And if the infection reaches this point, your dog could suffer congestive heart failure and die.
Now That You Know
Keeping a watchful eye on your dog's stool is not a very pleasant task. However, as you have learned in this article, it's the best way to find out if your dog has whipworms, hookworms, a tapeworm or roundworms. If you do see the symptoms of one of these worms, you can get the dog in to see your vet and get treatment started – to end the dog's suffering. If your dog could talk, he or she would definitely give you a big "thank you" for ridding it of a nasty parasite .