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Wall Street Decline Takes Its Toll...
As Immunotherapy Revolutionizes the Cancer Treatment...
Expanding Use of NGS Has Largely...
Quadruple Helices Appear To Have Role...
When coupled with mass spectrometry, liquid chromatography forms a powerful technique with high sensitivity and selectivity. The technology is especially relevant to the specific detection and identification of chemicals in complex mixtures, which will be confirmed by the studies reviewed in this article.
"Lectin-affinity chromatography is a popular medium for the purification of oligosaccharides, glycopeptides, and glycoproteins," noted Srinivasa Rao, Ph.D., technical manager at Dionex. Concanavalin A (Con A), a lectin derived from the jack bean, Canavalia ensiformis, is the lectin of choice for many purification protocols. At neutral and alkaline pH, it exists as a tetramer of four identical subunits weighing in at approximately 104 kDa.
Con A is noted as one of the best characterized and widely used lectins, given that it binds to α-mannose and to α-glucose, although with weaker affinity to the latter. "However, its utility is limited by the fact that it is ordinarily incorporated into manually operated agarose bead-based spin columns."
As Dr. Rao explained, this limits the number of purification cycles for which the column can be used, with the result that costs are driven up and time is lost. With the growing interest in investigations in the realm of glycoproteomic studies, such as biomarker identification, there is an increasing need for a robust HPLC lectin column.
For this reason, Dr. Rao and his coworkers have focused on the development and function of new monolithic affinity columns. Their recently designed column is known as the ProSwift ConA-1S, a polymeric monolith prepared by in situ polymerization followed by functionalization with Con A.
The monolith is a cylindrical polymer rod containing uninterrupted, interconnected flow-through pores, with surface area greater than nonporous bead-based columns. The structure consists of small pores that contribute surface area and larger openings that allow reduced back pressure at elevated flow rates. This approach results in short mass-transfer distances that produce improved efficiency, even at elevated flow rates, Dr. Rao explained. The HPLC compatibility of this column allows automatic sample injection, high throughput, and excellent reproducibility, he remarked.
To give an example of successful application of their column technology, Dr. Rao described the purification of horseradish peroxidase, a glycoprotein rich in high-mannose type glycans. Bound to the Con A column, it was eluted with α-methyl-mannopyranoside. This high-capacity Con A column retained the high specificity toward alpha mannose residues as shown by binding and elution investigations of several standards.
Dionex' new HPLC monolithic Con A affinity column, ProSwift™ ConA-1S, allows automatic injection and on-line elution monitoring, resulting in sharper peak shape and requiring smaller elution volume of the more enriched fractions, he explained. The column can also be used for glycan and glycoprotein analysis and purification. The ProSwift ConA-1S column can be regenerated easily by washing with conditioning buffer after sample binding and elution, said Dr. Rao. "Our durable column chemistry allows hundreds of run cycles with minimal capacity loss."
Luisa Pereira, Ph.D., principal scientist in chromatography consumables and speciality products at Thermo Fisher Scientific, is developing analytical tools based on porous graphitic carbon columns to advance protein phosphorylation studies.
"Unfortunately proteins tend to be too large to analyze quantitatively in their native states, and so a formal process of denaturation and digestion of the protein had to be undertaken," said Dr. Pereira.
This strategy generates a series of peptides among which the extremely polar class of glycopeptides and phosphopeptides are of particular interest. However, these compounds present a challenge due to their poor retention with standard reverse-phase liquid chromatography packing media. For this reason Thermo Fisher Scientific began using porous graphitic carbon, noted for its strong retention of polar compounds.
To assess the utility of this approach, Dr. Pereira and her colleagues evaluated the separation of a collection of polar and nonpolar peptides. The retention of polar peptides GHK and TSK is greatly affected by the pH of the mobile phase. Both these peptides have a basic terminal lysinyl residue and feature no acidic residues other than the carboxy terminus. When the pH of the mobile phase is increased, reaching near-pI values, the retention of the peptides is greatly increased. The overall increase in charged states at higher pH may result in decreased hydrophobic interactions, explaining the drop in retention. For polar fragments, the increase in temperature was found to improve peak shape.
"Furthermore, we found that capillary columns allowed for increased sensitivity, at the same time allowing rapid elution methods. The fact that we are able to analyze complex mixtures of polar peptides establishes that porous graphitic carbon columns are an effective complement to reverse-phase platforms."
Thomas E. Wheat, Ph.D., research scientist at Waters, is working with automated systems for controlling pH in the chromatographic separation of biological macromolecules. "The basis for separations is employing a medium that confronts the net surface charge on the target proteins with oppositely charged groups on the ion-exchanger." Because the protein surface is covered with both weakly acidic and weakly basic functionalities, both the net charge and the 3-D charge distribution can be controlled with the buffer pH.
There are two purification strategies; the bound proteins can be eluted from the column using a gradient of increasing salt concentration, the conventional approach, or a gradient of changing pH, which is a more demanding and therefore less common method. However, pH optimization is the most effective means of achieving selectivity. The classic analytical approach to constructing a pH gradient is the use of solutions of disodium hydrogen phosphate (Na2HPO4) and sodium dihydrogen phosphate (NaH2PO4), an acid/base conjugate pair.
Dr. Wheat and his colleagues have developed a software system to automatically calculate the proportions of the buffers for a given pH. The simple implementation of this function is based on calculations from the pKa. This software algorithm simplifies the development and routine execution of bioseparation methods.
"The platform, known as Auto Blend Plus Technology, provides accurate, automated pH control for chromatographic mobile phases. The algorithms are designed to compensate for ionic strength effects on pH."
These functions, although relatively straightforward, are extremely powerful. Dr. Wheat's team has been able to separate mixtures of monoclonal antibodies, which differ in relatively subtle properties, including their amino acid sequences and secondary modifications.
"We are able to identify a specific monoclonal antibody from a panel and say which of these 10 antibodies in a mixture we have isolated, based on retention time," Dr. Wheat said. "While I can't separate every antibody mixture, by manipulating the pH I can get a separation of just about all of them if I pick the right 10."
The Auto Blend Plus Technology is not a clinical tool at this point, but it has numerous applications in biopharmaceutical quality control and will no doubt be of interest to R&D pharma groups. "We have been focusing on this technology for a long time and I am happy to see it progressing to this level."
K. John Morrow Jr., Ph.D. ([email protected]), is president of Newport Biotech and a contributing editor for GEN.
K. John Morrow Jr., Ph.D. ([email protected]), is president of Newport Biotech and a contributing editor for GEN.
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Today�s Human Events reports that the Department of Justice continues their assault on the First Amendment rights of American citizens, this time�an individual�s right of�Freedom of Speech versus the DOJ�s�previous assaults�on the Freedom of the Press consisting of threats and intimidation of AP and Fox investigative reporters.
This stuff could have been taken�directly from George Orwell�s novel, �1984? in which Newspeak and thought control were prevalent in Big Brother�s Inner Party, in which a Ministry of Justice would break any laws they considered themselves above, just like the Obama regime.
The Administration�s outreach to the Muslim community will include ...Read more

subset: commoncrawl


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SALEM-For one weekend every year, antique cars of all shapes and sizes flood Salem for the annual Salem Super Cruise. Friday marked day two of this year's event and with the weekend looming, people from across the area crowded downtown to showcase their cars and trucks while others simply chose to sit, watch the passing scene, and listen to live music.
"We come every year," said Phil Rager of Sebring as he sat in front of a 1977 Chevy Impala owned by his son Phil Jr. "It's nice just to sit back, relax and talk with other people and see their cars."
For those who wished to avoid the noise and bustle of downtown, an antique car show held in Centennial Park offered a quieter alternative.
Article Photos
John Gamble, of Winona, shows off his 1950 Chevrolet Hardtop on Friday at an antique car show in Centennial Park in Salem. The show was an alternative to the Super Cruise going on in downtown Salem
"I like to come here to the park," said Leonard Lance from Salem. "The cruise downtown is more for cars that like to rev their engines and make noise. I just like to sit in the shade with my car and relax."
Lance was in attendance with his 1966 Chrysler 300 which he had restored to its original state. He bought the car the year it came out, but by the early '80s it was sitting in a barn, unused and in need of repair. It was then that he made the decision to restore the car rather than sell it.
"I needed to do one or the other," Lance said. "I just liked driving it so much that I couldn't stand to get rid of it."
Lance had parts shipped in from all over the country and completely rebuilt the car to its original state. The engine was the only thing he didn't touch. He belongs to the Antique Automobile Club and displays the car a various local events.
"When I first bought the car I had no idea I'd still have it 46 years later," Lance said. "I originally just used it to commute to work, but it's wound up going all over the country with me."
Another attendee who rebuilt his car from scratch was John Gamble from Winona who brought his 1950 Chevy Hardtop. Gamble purchased the car over eBay four years ago, went all the way out to Des Moines, Iowa to get it, and then spent a year completely restoring it.
"The car was in pretty bad condition when I first got it," Gamble said. "That was actually a good thing because I got it cheap."
One reason Gamble was willing to drive over 700 miles to buy a broken down car was its nostalgic value. Gamble owned a 1950 Hardtop when he was 17. It was his first car.
"I had a lot of great memories in my old car," Gamble said. "I just wanted to drive that same one again. When I saw it on the Internet, it was something I couldn't pass up."
One of the more unusual entries of the evening belonged to Ron and Barb Devies from Marlboro, Ohio. The couple was showing their 1964 Cadillac which doubled as both a hearse and ambulance. Ron, the Police Chief in Marlboro, worked as an EMT when he was younger and drove the same type of car.
"I have five other Cadillac ambulances," Devies said. "They are interesting cars that you don't see too much of. It's fun to have something that I drove when I was younger."
The vehicle came equipped with a siren and has all the supplies an ambulance would need under the floorboards in the rear. According to Devies many funeral homes prior to the 1970s also provided ambulance service. His car was owned decades ago by a funeral home in Logan, Ohio and, for a time, was also the township's only ambulance. Since purchasing it four years ago, Devies has loaned out his car to a couple of funerals of classic car enthusiasts.
"There were a couple of people who loved old cars and wanted to take their last ride in a classic," Devies said. "I can't blame them, they don't make cars like this any more."
A common thread among many of the entries seemed to be the sheer enjoyment people got from simply working on their cars, with many of them devoting years of their time and money.
"After I got done with my Hardtop, I went looking for another car to restore and I'm currently working on it," Gamble said. "It's something that I love to do in my free time. For me, working on the car is almost more fun than driving it."


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Alcatraz II Laptop Backpack - Berry Purple
Item# WL4734
Detailshttp://www.kipling-usa.com/alcatraz-ii-laptop-backpack/100140540.html Alcatraz II Laptop Backpack Berry Purple
Item# WL4734
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NEW and improved with room for your beloved laptop and airline carry-on acceptable! Able to be wheeled or carried backpack style. Innovative features allow for use as carry-on luggage or a back-saving solution for students with a heavy homework load. Dimensions: 16.25" x 18" x 8.5" Weight: 5.53 lbs.Read More
- Interior pouch accommodates 15" laptop with Velcro closure
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- 1 front zippered pocket with mesh-lined interior pouch pocket
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on December 6, 2012 - 6:26 PM
, updated December 6, 2012 at 6:39 PM
A 47-acre former manufacturing site on Wheeler Street in the City of Tonawanda is ready for new business.
The site of the former Spaulding Fibre manufacturing plant has undergone $20.6 million in environmental cleanup and infrastructure construction to prepare it to become the Spaulding Commerce Park.
The land, owned by the city, now has new roads, utilities and landscaping in preparation for commercial and light industrial development.
"It took eight and a half years to make this happen," said City of Tonawanda Mayor Ronald Pilozzi. "It's shovel-ready. It's well within a mile from the Youngmann Expressway."
Pilozzi joined county, state and federal officials at the site on Thursday to mark the completion of the cleanup. He said the project could not have been accomplished without all of those levels of government working together.
The former plastics and laminates manufacturing site, once owned by Spaulding Fibre Co., was abandoned in 2005 after the company's bankruptcy proceedings were completed. It had been closed since 1992, and four acres of the land was part of a state Superfund cleanup.
Funding for the cleanup, the demolition of vacant buildings and the construction of new infrastructure came from the state Department of Environment Conservation, Erie County, Empire State Development Corp., the City of Tonawanda, the U.S. Department of Housing and Urban Development and National Grid.
Pilozzi said the city has had several inquires from businesses about the site, which can be split into parcels depending on the needs of a company.
"This problem was too big for any one agency to handle alone," County Executive Mark C. Poloncarz said in a written statement. "And it took more than eight years of work involving participation from the public and private sectors to transform what was an environmentally hazardous neighborhood eyesore into a shovel-ready business park."
email: email@example.com


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MARTINSBURG - When Martinsburg native Charles L. Carey, 56, decided to enlist in the U.S. Army in the early 1970s, he was signing up for a reason that was likely different than many other soldiers who either volunteered or were drafted.
"My brother had already been in there, and we're a close-knit family, and he didn't write, we didn't hear from him, so I told my mother I was going to go take the test for the Marines and the Army and I passed both of them but the Army called me first," Carey said. "That's how I got into the military, going to look for my brother. Wherever he was, I was going to go find him."
Carey served in the Army's 25th Infantry Division, stationed in Hawaii, from 1974 to 1976. Carey's brother, a two-term Army medic, was about seven years older than Carey at the time.
Article Video
Charles Carey spoken poetry
While Carey was eager to be deployed to Vietnam so he could try and find out what happened to his brother, his unit remained stationed in Hawaii.
"We saddled up a couple times and were on the landing fields to go (to Vietnam) two times, but they canceled us both times," Carey said. "Once I got in, I was hoping they would send us to Vietnam but they kept canceling us so I couldn't get there. All the time I was hoping they would let us go so I could be somewhere to inquire about my brother because there was no other way I could find out where he was."
It wasn't until after Carey had enlisted and been stationed in Hawaii that he learned his brother was safe.
Article Photos
Journal photo by Rob Agnir
Charles L. Carey served in U.S. Army's 25th Infantry Division.
"Once I joined then he contacted me and he was home when I'd already signed up for the soup," Carey said. "I was glad that he was home, but then I had my obligation to complete."
During his time in the service, Carey was a private first class and formed close friendships with several men he served with and led.
"I figured if I did well I would get rewarded and I stayed to that. I didn't go into town much because I knew by being a squad leader I had to be a leader to some degree, and that's what they trained me to be and that's what I was going to be," he said.
See HERO, A2
After he left the Army, Carey moved back to Martinsburg with his family. Carey admitted that it took him time to get re-acclimated to civilian life and that he developed a drinking problem when he came home.
However, through a combination of treatment at the Martinsburg Veteran Affairs Medical Center, education and support from friends and family, Carey said he's been able to stay alcohol free for the past three years.
"It took a lot of people to put Humpty Dumpty back together again," Carey joked.
Nowadays Carey volunteers with the Patriot's Path Foundation in Martinsburg. The nonprofit organization helps military veterans get back on their feet by providing affordable housing and other services.
"It's very important because a lot of veterans have issues. They have alcohol issues, they have drug issues, they have so many mental issues, but the thing of it is it's very important for a veteran to be able to stand and be committed to his life, the straightening of his life," Carey said. "If he continues to go down that path, with all the help that's out there for them some of them do ignore that help, thinking that they can do something the same way and get different results."
Speaking from experience, Carey said that one of the most important steps for veterans who need help is being humble enough to realize they need the help and then ask for it.
"That big bad soldier stuff is over, when we were there we had to be big and bad, but the time of big and bad is over," Carey said. "I found that out myself, because when I learned to humble myself and clear my mind and see what life's really about, it's about being humble.
"Though the military, that gave me that experience and that discipline to now to come fall back on," added
In addition to his work with the Patriot's Path Foundation, Carey volunteers with the local Church Without Walls Ministries Inc. and volunteers and speaks at the Martinsburg-Berkeley County.
Along with volunteering, Carey is a published author whose book, "Lions at the Gate," contains more than a dozen of his poems. Carey said he has written more than 1,000 pieces of poetry and short stories and that he wants to write as many as 2,000. He is also in the process of reviewing the manuscript for his second book of poetry.
Carey primarily spends time with his six children and large extended family, writing poems and short stories and giving back to the community. "Lions at the Gate" is available at www.authorhouse.com.
"Your commitment is to give back to life what life has given you," Carey said. " Keep on giving until you can't give no more. That's what life's about."
Staff writer Matt Armstrong can be reached at 304-725-6581, or firstname.lastname@example.com


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David Zalubowski/Associated Press file photo
David Zalubowski/Associated Press file photo
BOISE, Idaho � Colorado State is coming off its best win of the year, a blowout victory over UNLV that has given first-year coach Jim McElwain the chance to preach the importance of building on success.
The Rams, powered by 24 first-half points and a flurry of turnovers, rolled over the Rebels 33-11 in Fort Collins last Saturday.
McElwain said the challenge facing his young team now is avoiding the so-called �one-hit wonder� tag.
The Rams� goal of posting back-to-back wins faces a tough test in today�s matchup with Boise State.
The Broncos (8-2, 5-1 Mountain West) are in a tie for first in the conference and are playing their last game at home this season.
Colorado State (3-7, 2-4) will be making its first trip to Bronco Stadium.


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Director General Mike Karlen has chosen Megan Marlene Wetzel as a princess in the 76th Mountain State Forest Festival.
Wetzel is the daughter of Lori Wetzel of Belington and Michael Wetzel of Parsons.
She is the granddaughter of Dottie Talbott and the late Paul Talbott and Mr. and Mrs. Robert Wetzel and the late Shirley Wetzel of Elkins.
Article Photos
Wetzel graduated from Philip Barbour High School with the class of 2012 and presently attends West Virginia Wesleyan College. She is majoring in psychology.
She also took classes from Alderson-Broaddus College while in high school.
She was a four-year member of the Lady Colts Soccer Team, lettering two of those years. She was secretary of the Future Business Leaders of America, was a member of the Friends of Rachel and was Student Council class representative.
She attends the Asbury United Methodist Church. She is an advocate for breast cancer awareness, enjoys traveling, playing soccer, spending time with family and friends and especially watching her sister play sports.
Wetzel and other princesses are set to take part in the Forest Festival coronation ceremony today at the campus of Davis & Elkins College.


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8 Children's Movies Studios Don't Have the Balls to Make
For my day job, I work for a major feature animation studio, and one of their coolest and most dangerous policies is that any employee can submit a pitch for a movie idea. They're looking for what they call in the biz four-quadrant movies, or what you would think of as "family" movies: Something with enough wit or thrills to keep adults interested, but doesn't involve penis jokes or disembowelment.
I've come up with quite a few ideas that were all unfortunately rejected. Not by management, technically, as I wasn't able to get as far as submitting them, but by my co-workers, who physically prevented me from hitting the "submit" button on the computer. They said something about "career suicide" and how they were "saving me from myself."
They are watching me like a hawk at work, so I'm going to put these up on Cracked and hopefully one of you guys can help me bypass these so-called gatekeepers of taste and get them in front of some studio heads. I will split the profits with you 50-50.
#8. Hostel (For Kids)
Hostel made a decent box office profit for a torture porn movie and got a massive amount of buzz. However, being a gratuitously gory horror movie really limits its target demographic. Imagine how many people it could reach if they remade it for a wider audience.
All you have to do is take out everything that made the movie inappropriate for kids, and you're left with, um ... people being negative to other people, and some form of red liquid.
My proposal is that we have a very mischievous young child who goes around and asks other kids if they want to look at his plastic chainsaw. While they are distracted by the brightly colored toy and its moving parts, he squirts ketchup on them, getting their clothes dirty and -- this is the scary part -- causing their parents to be mad at them. I can tone this down if it's still too horrifying.
One of the tragic victims.
#7. Office Space (For Kids)
"Are you just going to attach the phrase 'for kids' to the end of well-known movie titles?" you might be asking right now. Everyone keeps asking that. Is that some kind of no-no? I find that creativity goes much faster when you do the exact same thing for each project, like that time I had assignments in creative writing, American history, molecular biology and physics 8B due at the same time and I turned in a biography of Abraham Lincoln for each one.
Anyway, while Office Space didn't do so well at the box office, it took on a new life as a cult classic, and anyone would love their kids' movies to be worshiped and imitated and made into memes that get old as soon as they come into existence. I find that the themes of Office Space translate perfectly into the world of, say, a preschool, where existential ennui from the drudgery and bureaucracy of the daily routine is common. I haven't been in preschool for decades, but I think I am remembering it correctly.
So many TPS reports to finish before nap time.
I think toddlers will really be able to identify with being bored of life. What 3-year-old hasn't complained about how repetitive and mind-numbing it is to wake up in the morning every day, identify some shapes and colors, make mud pies, chase their sister around the house, color Spider-Man, play with bulldozers in the sandbox and practice pooping? It's a wonder they don't kill themselves.
#6. Scarface Squirrel
Brian De Palma's masterpiece about the resonating themes of, um, cocaine and shooting a lot of people, or something, is renowned amongst both movie critics and hip-hop artists, and how many things can you say that about?
One audience, however, has been barred from appreciating Scarface until now, and that is elementary-school-aged children. Now, through the magic of talking animals and a massive amount of censorship, they too can enjoy this cultural milestone.
Since the cocaine and violence need to go, according to my prudish co-workers, the Colombians are instead angry at Tony because they are flamingos and he called them pelicans, which is really insulting.
This is what we in the business call an homage.
And it would be unthinkable to remove his iconic line, "Say hello to my little friend," but since we can't have guns, he is actually introducing them to his young nephew, who is visiting.
Then he sends the boy off to play, and they have a big shootout with Nerf guns. One of them hits him in the eye, just like his mom always warned him would happen, and he learns a valuable lesson and changes his ways.
Really just a few minor changes, while preserving the essence of the film.
#5. Merry-Go-Round
One surefire way to make a hit these days is to base a movie on an amusement park ride, like the blockbuster Pirates of the Caribbean series, or The Haunted Mansion, or Indiana Jones.
Disney will never give up one of its properties, so I'm going somewhere it'll be easier to buy the rights -- temporary carnivals and deteriorating children's parks and zoos in my local area.
The old merry-go-round in particular has a lot of potential to become a fleshed-out story because merry-go-rounds have so much character. And by character, I mean creepiness. Ever wonder why so many merry-go-round horses look terrified?
Perhaps it is because they've all been impaled with giant poles.
I mean, that expression makes perfect sense to me when you notice that he has been stabbed right through the torso. My idea was that the merry-go-round could come to life at night, a la Night at the Museum, and a bunch of kids could have adventures with the horses before they had to go back to the merry-go-round at dawn and be impaled once more by the cruel poles.
In addition to the obvious thematic connection, there should be some great potential for visual tie-ins to the Buddhist wheel of life, representing the concept of samsara, the inescapable cycle of birth, life and death that all are destined to repeat.
Stephen Shephard via Wikimedia Commons
Kids love nothing more than contemplating ancient philosophy.
I hear a lot of parents complaining about how Hollywood needs to make more films with strong religious content for children, so I think this ought to make some parents' groups really happy.
Sure, I've gotten an earful from naysayers who say that children don't enjoy a fatalistic exploration of the futility of man's struggles culminating in resignation to a low-key existential dread, but I think these people are just party poopers who have forgotten the joy of childhood.


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Pronounced: Tay-KEE-car-de-ya
Krisha McCoy, MS
Tachycardia is a rapid heart rate of more than 100 beats per minute. Sinus tachycardia, from the heart's sinus node, is a normal response to exercise, illness, or stress.
There are several types of abnormal tachycardias or
arrhythmias. These can come from two places:
This condition can be life-threatening, but it can be treated. If you think you or someone you know has this condition, call for emergency medical services right away.
Copyright © Nucleus Medical Media, Inc.
This condition is caused by abnormal electrical impulses that control the heart.
Factors that may increase your chance of tachycardia include:
Tachycardia may cause:
Your doctor will ask about your symptoms and medical history. A physical exam will be done.
Tests may include:
Talk with your doctor about the best treatment plan for you. Treatment options include the following:
Medications to treat tachycardia include:
is done during an electrophysiology study. Radiofrequency energy or cold energy is used to destroy the abnormality and possibly cure the problem.
An electric shock is applied to the heart to stop the abnormal rhythm. This treatment may be done for life-threatening rhythms, such as
ventricular tachycardia
ventricular fibrillation. It is also done for milder arrhythmias, such as
atrial fibrillation.
can be surgically placed into your body. This device monitors your heartbeat. It can apply a shock to correct an irregular heartbeat.
To help reduce your chance of tachycardia:
Heart Rhythm Society
Society of Thoracic Surgeons
Canadian Cardiovascular Society
Health Canada
Arrhythmias. American Heart Association website. Available at:
Accessed December 30, 2014.
Cardioversion of atrial fibrillation. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed.
Updated November 12, 2014. Accessed December 30, 2014.
Implantable cardioverter defibrillator (ICD). EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed.
Updated November 19, 2014. Accessed December 30, 2014.
Risk factors and prevention. Heart Rhythm Society website. Available at:
Accessed December 30, 2014.
Supraventricular tachycardia (SVT). EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed.
Updated June 5, 2014. Accessed December 30, 2014.
Ventricular tachycardia. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed.
Updated August 8, 2013. Accessed December 30, 2014.
Last reviewed December 2015 by Michael J. Fucci, DO
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
Copyright © EBSCO Publishing. All rights reserved.


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Welcome to the Brothers Karamazov Website!
Here you will find a wealth of materials on Dostoevsky's novel, including ideas
for reading, researching, and writing.
The discussion pages are reserved for Dartmouth College students.
Questions or comments about the site can be sent to Karen Gocsik, Executive Director of the Writing and Rhetoric Courses, at email@example.com.
Enjoy the site!


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Margaret M. "Margie" Smith, 89, Altoona, went home to be with the Lord Tuesday after an extended illness.
She was born in Altoona, daughter of the late Herman F. Sr. and Anna (Richards) Morgan.
Surviving are three children: Richard of Vandergrift, Bonnie Luther of Powder Springs, Ga., and Kenneth and wife, Lori, of Altoona; seven grandchildren; four great-grandchildren; two sisters: Doris Hauk and Lillian Marko; a brother, Austin Morgan; and several nieces and nephews.
She was preceded in death by her husband, Merrill E. Smith, on Dec. 2, 1974; and a brother, Herman Jr.
Margie was a member of Simpson-Temple United Parish and had recently attended Bethany Lutheran Church, and she had been active in numerous church activities over the years.
Friends will be received from 2 to 4 and 6 to 8 p.m. Friday, Oct. 12, 2012, at Mauk & Yates Funeral Home Inc., Juniata. A funeral service will be held at 11 a.m. Saturday, Oct. 13, 2012, at Bethany Lutheran Church, the Rev. Paula Schmitt officiating.
In lieu of flowers, please make contributions to Home Nursing Agency Hospice, 201 Chestnut Ave., P.O. Box 352, Altoona, PA 16603; or Crossties Ministries Inc., 5254 Miranda Way, Powder Springs, GA 30127.


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|Welcome to the MANGA Forum.
|You will have to register before you can post: log in or sign up at the top of the page to proceed. To start viewing messages, select the forum that you want to visit from the selection below.
What is the coolest and most popular manga series for you?
The Keeper of Precepts/For Friends and For Tomorrow.
I think between Dragon Ball and Sailor moon.
there is black cat and then there is tenchi and gundam wing
then nora then try gun. i got alot more i just can not think of them off the top of my head right now but there is alot for me any way.
i would say inuyasha, death note and bleach theres more but can't really think right now... :>
<~~U r the pop 2 my tart, the star in the sky, my love to the heart~~>
The Keeper of Precepts/For Friends and For Tomorrow. Since nobody think of it, I would say Nanoha manga is very good.
'' It hard for me to reach god form.. but i must keeep fighting to survive HUZZAH!''
heck ya battle and destruction is my game.... and drawing of course.
gurren lagann duhhh
"Chou!!!! Tengen Toppa Giiiiigaaaa Drilluuuuuu Breakerrrrrr!!!!
the most well known and popular manga i own are akira toriyama's dragon ball, tite kubo's bleach, and watsuki nobuhiro's rurouni kenshin. another popular is rumiko takahashi and i have the first three volumes of her newest series rin-ne.
bleach,deathnote,naruto are the coolest for me.


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12-Year-Old Mirko Caballero Climbs His First 5.14b
Twelve-year-old American climber Mirko Caballero redpointed his first 5.14b yesterday when he sent Stop Sika in Rawyl, Switzerland. According to his 8a.nu logbook it took him four tries to stick the route. "I felt strong after two weeks bouldering in Magic Wood," Mirko writes, referring to the famous bouldering area in Switzerland where he spent the past couple of weeks crushing boulder problems up to V13.
Mirko has been climbing strong in the past year, redpointing at least five routes rated 5.14a or harder since last November. He also flashed Slow Food (Right) (5.13d) and has onsighted at least eight climbs rated 5.13b. Mirko's bouldering resume is equally impressive, as he sent One Summer in Paradise (V13) on August 14, 2013, as well as at least 25 problems rated V11 or harder.
Check out this video of Mirko Caballero working and sending his first V12, The Aquarium, at 11 years of age:
The Aquarium, My First V12 (8A+) from Mirko Caballero on Vimeo.


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My suggestion for closing the budget gap
December 18, 2012 - Harry Eagar
Tax the churches.
Tens of trillions in tax subsidies for organizations that contribute, so far as I can see, nothing measurably positive, although I admit they provide a psychological crutch for people who cannot face reality.
I call as a witness Bill O'Reilly, who opined a week or so ago that it is OK for the government to allow sectarian outbreaks in the public space of all of us because "Christianity isn't a religion."
As the Cockneys say in East London, I 'eard diff'rent.
However, O'Reilly is a leading exponent of the religious approach to public life. He says that the Constitution would ban public favoritism toward, say, Presbyterians, because they are a religion (I'm sure the Presbyterians thank him for that, and he should be grateful because history teaches that an angry Presbyterian is a fearsome thing).
Well, does that mean we can at least start taxing the tens of thousands of non-denominational Christian churches?
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P.S. Please take a moment to vote for me!
October 8, 2007
Yes My Kids Are Always This Sweet
P.S. Please take a moment to vote for me!
22 comments:
AWE!!! I got a speeding ticket a few weeks ago and when i came home I started to get teary eyed, Mason immediately started singing twinkle twinkle!!!ReplyDelete
OUR kids are SOOOO SWEET!
Hi Stephanie, I tagged you with this little meme.
Steph, your boys are adorable. I catch those sweet moments every once in a blue moon, too. heheReplyDelete
How cute...and you got it on tape! I can't wait to see the interaction between my 2 kiddies soon. I know it won't always be as sweet as this instance, but you still give me something to look forward to!ReplyDelete
I see Mark in Gray here. Mark will settle on our couch while Matt entertains him. SO CUTE!!ReplyDelete
These moments are few and far between at my house. Not that they aren't sweet to one another, but like you said, they're moving so fast, it's hard to capture it. And by the time you get your camera to tape it, the moment's gone! :) It's awesome that you caught this on tape!ReplyDelete
How sweet! He was taking care of his baby bro!! Awwwwww...ReplyDelete
That video right there makes me want to have another baby...just so Jonah gets to have those sort of moments with a sibling.ReplyDelete
They are too cute!
Aww! He's such a good 'lil singer too!ReplyDelete
Awww, isn't that sweet? :)ReplyDelete
Such a sweet moment to catch on video:)ReplyDelete
AWWW - that is adorable.ReplyDelete
ohhhh thats so cute!ReplyDelete
Gray looks so cute laying so still! he he.ReplyDelete
The three of them will be such great friends their whole lives, with them all being so close. Love it!
That is too cute! So neat that you were able to capture that!ReplyDelete
You'd think you just reminded them about Santa watching all the time or something....Not that I ever use that line or anything...ReplyDelete
awwww!! that's a reflection of their parents!!ReplyDelete
sooooo loving!!!
they're sooo cute!
Oh my that is the sweetest!!! I don't think I've ever seen Gray sit still for that long ;)ReplyDelete
Love your pillows too!
Love it!! The boys can be so sweet to each other in one moment can't they!!!? Loveit loveit loveit!!!!ReplyDelete
That was super cute! He was about to get rowdy like Zachary there at the end! LOL!ReplyDelete
aww to cuteReplyDelete


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Brain Body and Bytes: Psychophysiological User Interaction
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The human brain and body are prolific signal generators. Recent
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Quality Education in the Benedictine Tradition
May 7, 2013
Dr. Junlei Li has been named to a new, three-year visiting professorship in early learning and children's media at Saint Vincent College, according to Br. Norman W. Hipps, O.S.B., president. Li will serve as an associate professor of psychology in Saint Vincent College's School of Social Sciences, Communication and Education, working with Saint Vincent faculty and the staff at the Fred Rogers Center for Early Learning and Children's Mediato draw a future generation of scholars to the legacy of Fred Rogers. "I am very pleased to consider the role that Dr. Li can play in more deeply engaging our students in teaching, application and research at the Fred Rogers Center, which will help to expand the reach of Fred Rogers' work to a new generation," Hipps said. Li was formerly the principal research scientist at The Fred Rogers Company. He was also a senior fellow and past director of applied research and evaluation at the Office of Child Development at the University of Pittsburgh. His work integrates developmental science with training, media and communication development to improve children's lives in schools, orphanages and community programs. He was previously a principal investigator at Carnegie Mellon University where he designed and led research and development projects, funded by the U.S. Department of Education, to narrow the science achievement gap in under-served urban schools. A graduate of the University of Notre Dame where he earned a bachelor of science degree in computer science with highest honor, he earned a master of arts degree in instructional science and a Ph.D. in psychology at Carnegie Mellon University. Li was born and raised in China and emigrated to the U.S. with his family at the age of 16. He and his wife adopted two daughters from China. They maintain strong ties with China through both professional and humanitarian work on behalf of orphans with disabilities. He is the author or co-author of journal papers, book chapters, op-ed commentary, policy papers, evaluation reports, conference presentations and invited symposiums. He has taught undergraduate and graduate courses in psychology and education at the University of Pittsburgh School of Education and the Carnegie Mellon University Department of Psychology. Dr. Li's position at Saint Vincent is being funded by a generous grant from The Heinz Endowments.
Photo: Dr. Junlei Li
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The history of the U.S. president
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Top Definition
To Shoot somebody
door Tronic187 3 december 2011
Trending Now
Can you define these popular missing words?
Bodywork is generally the massaging on a persons body in long relaxed strokes and using ones body to give an extra sensual feeling to the receiver. It usually means both persons are nude. Sometimes escorts use the word bodywork to describe sexual intercourse in a non direct way.
Her idea of bodywork is for you feel good and have a sexual release
door tom deve123 5 augustus 2009


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Index of content:
Volume 113, Issue 19, 21 May 2013
Spin injection from Heusler alloys into semiconductors: A materials perspective113(2013); http://dx.doi.org/10.1063/1.4802504View Description Hide Description
The notion of using electron spins as bits for highly efficient computation coupled with non-volatile data storage has driven an intense international research effort over the past decade. Such an approach, known as spin-based electronics or spintronics, is considered to be a promising alternative to charge-based electronics in future integrated circuit technologies. Many proposed spin-based devices, such as the well-known spin-transistor, require injection of spin polarized currents from ferromagnetic layers into semiconductor channels, where the degree of injected spin polarization is crucial to the overall device performance. Several ferromagnetic Heusler alloys are predicted to be half-metallic, meaning 100% spin-polarized at the Fermi level, and hence considered to be excellent candidates for electrical spin injection. Furthermore, they exhibit high Curie temperatures and close lattice matching to III-V semiconductors. Despite their promise, Heusler alloy/semiconductor heterostructures investigated in the past decade have failed to fulfill the expectation of near perfect spin injection and in certain cases have even demonstrated inferior behavior compared to their elemental ferromagnetic counterparts. To address this problem, a slew of theoretical and experimental work has emerged studying Heusler alloy/semiconductor interface properties. Here, we review the dominant prohibitive materials challenges that have been identified, namely atomic disorder in the Heusler alloy and in-diffusion of magnetic impurities into the semiconductor, and their ensuing detrimental effects on spin injection. To mitigate these effects, we propose the incorporation of half-metallic Heusler alloys grown at high temperatures (>200 °C) along with insertion of a MgO tunnel barrier at the ferromagnet/semiconductor interface to minimize magnetic impurity in-diffusion and potentially act as a spin-filter. By considering evidence from a variety of structural, optical, and electrical studies, we hope to paint a realistic picture of the materials environment encountered by spins upon injection from Heusler alloys into semiconductors. Finally, we review several emerging device paradigms that utilize Heusler alloys as sources of spin polarized electrons.
- Top
- Lasers, Optics, and Optoelectronics
Polarization properties of single and ensembles of InAs/InP quantum rod nanowires emitting in the telecom wavelengths113(2013); http://dx.doi.org/10.1063/1.4804327View Description Hide Description
The absorption and emission polarization properties of InAs quantum rods embedded in InP nanowires (NWs) are investigated by mean of (micro-)photoluminescence spectroscopy. It is shown that the degree of linear polarization of emission (0.94) and absorption (0.5) of a single NW can be explained by the photonic nature of the NW structure. Knowing these parameters, optical properties of single NWs and ordered ensembles of these NWs can be correlated one to another via proposed model, so that polarization properties of NWs can be studied using ordered ensembles on as-grown samples. As an example, the polarization anisotropy is investigated as a function of the excitation wavelength on a NW ensemble and found to be in agreement with theoretical prediction.
Polarization dependence of absorption by bound electrons in self-assembled quantum dots113(2013); http://dx.doi.org/10.1063/1.4805061View Description Hide Description
In this paper, the effects of the incident light polarization on the bound to continuum linear absorption coefficient of quantum dot devices have been investigated. The study is based on the effective mass theory and the Non Equilibrium Green's Function formalism. For the bound to continuum component of the absorption coefficient, both of in-plane and perpendicular polarization effects are studied for different sizes of conical quantum dots. Generally, decreasing the dot's dimensions results in an increase of the in-plane polarized light absorption and in moving the absorption peak towards longer wavelengths. On the other hand, decreasing the dot's dimensions results in a decrease of the perpendicularly polarized light absorption coefficient and in moving the absorption peak towards longer wavelengths.
Investigation of the role of silver species on spectroscopic features of Sm3+-activated sodium–aluminosilicate glasses via Ag+-Na+ ion exchange113(2013); http://dx.doi.org/10.1063/1.4807313View Description Hide Description
The introduction of silver into the Sm3+-doped sodium–aluminosilicate glasses prepared by Ag +-Na+ ion exchange leads to the formation of different ionic silver species. Under 270 nm/250 nm excitation, effective enhancement of Sm3+ luminescence is ascribed to radiative energy transfer from isolated Ag + to Sm3+. Under 355 nm excitation, white light emission was realized by combining red orange light emission of Sm3+ with green light emission of Ag +-Ag+ and blue light emission of (Ag 2)+. Silver nanoparticles formed by further heat treatment are effective quenchers of luminescence from the corresponding excited states of Sm3+ ions.
Characterization of a hollow core fibre-coupled near field terahertz probe113(2013); http://dx.doi.org/10.1063/1.4804952View Description Hide Description
We describe the design and performance of a freely positionable THz near field probe based on a hollow core photonic crystal fibre-coupled photoconducting dipole antenna with an integrated sub-wavelength aperture. Experimental studies of the spatial resolution are compared with detailed finite element electromagnetic simulations and imaging artefacts that are a particular feature of this type of device are discussed. We illustrate the potential applications with descriptions of time domain near field studies of surface waves on a metamaterial and multimode propagation in a parallel plate waveguide.
Conversion mechanism of conductivity of phosphorus-doped ZnO films induced by post-annealing113(2013); http://dx.doi.org/10.1063/1.4805778View Description Hide Description
The effects of post-annealing on conductivity of phosphorus-doped ZnO (PZO) films grown at 500 °C by radio frequency magnetron sputtering are investigated in a temperature ranging from 600 °C to 900 °C. The as-grown PZO exhibits n-type conductivity with an electron concentration of 1.19 × 1020 cm−3, and keeps n-type conductivity as annealed at 600 °C-700 °C but electron concentration decreases with increasing temperature. However, it converts to p-type conductivity as annealed at 800 °C. Further increasing temperature, it still shows p-type conductivity but the hole concentration decreases. It is found that the P occupies mainly Zn site (P Zn ) in the as-grown PZO, which accounts for good n-type conductivity of the as-grown PZO. The amount of the P Zn decreases with increasing temperature, while the amount of Zn vacancy (V Zn ) increases from 600 °C to 800 °C but decreases greatly at 900 °C, resulting in that the amount of P Zn -2V Zn complex increases with increasing temperature up to 800 °C but decreases above 800 °C. It is suggested that the P Zn -2V Zn complex acceptor is responsible for p-type conductivity, and that the conversion of conductivity is due to the change of the amount of the P Zn and P Zn -2V Zn with annealing temperature.
Bidirectional optical switch based on electrowetting113(2013); http://dx.doi.org/10.1063/1.4807285View Description Hide Description
In this paper, we demonstrate a bidirectional optical switch based on electrowetting. Four rectangular polymethyl methacrylate substrates are stacked to form the device and three ITO electrodes are fabricated on the bottom substrate. A black liquid droplet is placed on the middle of the ITO electrode and surrounded by silicone oil. When we apply a voltage to one ITO electrode, the droplet stretches and moves in one direction and a light beam is covered by the stretched droplet, while the droplet yields a space to let the original blocked light pass through. Due to the shift of the droplet, our device functions as a bidirectional optical switch. Our experiment shows that the device can obtain a wide optical attenuation from ∼1 dB to 30 dB and the transmission loss is ∼0.67 dB. The response time of the device is ∼177 ms. The proposed optical switch has potential applications in variable optical attenuators, electronic displays, and light shutters.
Influence of fluorine on the fiber resistance studied through the nonbridging oxygen hole center related luminescence113(2013); http://dx.doi.org/10.1063/1.4807163View Description Hide Description
The distribution of Non-Bridging Oxygen Hole Centers (NBOHCs) in fluorine doped optical fibers was investigated by confocal microluminescence spectroscopy, monitoring their characteristic 1.9 eV luminescence band. The results show that these defects are generated by the fiber drawing and their concentration further increases after γ irradiation. The NBOHC concentration profile along the fiber provides evidence for an exponential decay with the fluorine content. This finding agrees with the role of fluorine in the fiber resistance and is discussed, from the microscopic point of view, by looking at the conversion mechanisms from strained bonds acting as precursors.
- Structural, Mechanical, Thermodynamic, and Optical Properties of Condensed Matter
Adhesion and friction control localized folding in supported graphene113(2013); http://dx.doi.org/10.1063/1.4804265View Description Hide Description
Graphene deposited on planar surfaces often exhibits sharp and localized folds delimiting seemingly planar regions, as a result of compressive stresses transmitted by the substrate. Such folds alter the electronic and chemical properties of graphene, and therefore, it is important to understand their emergence, to either suppress them or control their morphology. Here, we study the emergence of out-of-plane deformations in supported and laterally strained graphene with high-fidelity simulations and a simpler theoretical model. We characterize the onset of buckling and the nonlinear behavior after the instability in terms of the adhesion and frictional material parameters of the graphene-substrate interface. We find that localized folds evolve from a distributed wrinkling linear instability due to the nonlinearity in the van der Waals graphene-substrate interactions. We identify friction as a selection mechanism for the separation between folds, as the formation of far apart folds is penalized by the work of friction. Our systematic analysis is a first step towards strain engineering of supported graphene, and is applicable to other compressed thin elastic films weakly coupled to a substrate.
First-principles study of temperature-dependent diffusion coefficients: Hydrogen, deuterium, and tritium in α-Ti113(2013); http://dx.doi.org/10.1063/1.4805362View Description Hide Description
We report the prediction of temperature-dependent diffusion coefficients of interstitial hydrogen, deuterium, and tritium atoms in α-Ti using transition state theory. The microscopic parameters in the pre-factor and activation energy of the impurity diffusion coefficients are obtained from first-principles total energy and phonon calculations including the full coupling between the vibrational modes of the diffusing atom with the host lattice. The dual occupancy case of impurity atom in the hcp matrix is considered, and four diffusion paths are combined to obtain the final diffusion coefficients. The calculated diffusion parameters show good agreement with experiments. Our numerical results indicate that the diffusions of deuterium and tritium atoms are slower than that of the hydrogen atom at temperatures above 425 K and 390 K, respectively.
Thermal and optical properties of glass and crystalline phases formed in the binary R2O3-Al2O3 (R = La-Lu and Y) system113(2013); http://dx.doi.org/10.1063/1.4805536View Description Hide Description
Rare-earth aluminate (RAlO3, R = La–Lu and Y) glass and crystalline phases were prepared by containerless levitation in an aerodynamic levitation furnace. In the RAlO3 system, La, Nd and Sm aluminum perovskites solidified as glass and Eu–Lu and Y aluminum perovskites solidified as crystalline phases. The glass forming region decreased with decreasing ionic radius of the rare-earth element. Scanning electron microscopy images and x-ray diffraction results revealed the formation of a single RAlO3 phase from the undercooled melt. The glass transition temperature, T g, and density increased and the molar volume decreased with decreasing rare-earth element ionic radius. The refractive index at 589 nm exceeds 1.85 in each composition and a transparency of approximately 72% was achieved for the LaAlO3 glass.
Structural and vibrational stability of M and Z phases of silicon and germanium from first principles113(2013); http://dx.doi.org/10.1063/1.4804668View Description Hide Description
First-principles calculations were performed to investigate the structural feasibility of M and Z phases (novel monoclinic and orthorhombic structures recently reported for carbon) for silicon and germanium. The lattice parameters, bulk modulus, vibrational properties, and elastic constants are calculated using the local density approximation to describe the exchange-correlation energy, while the optical properties are calculated by using Many-Body Perturbation Theory in the G0W0 approximation. Our results indicate that silicon and germanium with the proposed crystal symmetries are elastically and vibrationally stable and are small band-gap semiconductors. We discuss the possible synthesis of such materials.
Controlled synthesis of buried delta-layers of Ag nanocrystals for near-field plasmonic effects on free surfaces113(2013); http://dx.doi.org/10.1063/1.4804171View Description Hide Description
We report on the shallow synthesis by low energy ion implantation of delta-layers of Ag nanocrystals in SiO2 at few nanometers under its free surface. Transmission electron microscopy observations, ballistic simulations, and reflectance measurements are coupled to define the conditions for which the synthesis is fully controlled and when, on the contrary, this control is lost. We show that low dose implantation leads to the formation of a well-defined single plane of nanocrystals, while for larger doses, sputtering and diffusion effects limit the control of the size, position, and volume amount of these nanocrystals. This paper provides the experimental evidence of the incorporated dose saturation predicted in the literature when implanting metal ions at high doses in glass matrices. Its consequences on the particle population and the plasmonic optical response of the composite layers are carefully analyzed. We show here that this saturation phenomenon is underestimated in standard simulation predictions due to diffusion of metal atoms towards the surface and nanocrystal nucleation during the implantation process.
Direct pulsed laser crystallization of nanocrystals for absorbent layers in photovoltaics: Multiphysics simulation and experiment113(2013); http://dx.doi.org/10.1063/1.4805039View Description Hide Description
Direct pulsed laser crystallization (DPLC) of nanoparticles of photoactive material—Copper Indium Selenide (nanoCIS) is investigated by multiphysics simulation and experiments. Laser interaction with nanoparticles is fundamentally different from their bulk counterparts. A multiphysics electromagnetic-heat transfer model is built to simulate DPLC of nanoparticles. It is found smaller photoactive nanomaterials (e.g., nanoCIS) require less laser fluence to accomplish the DPLC due to their stronger interactions with incident laser and lower melting point. The simulated optimal laser fluence is validated by experiments observation of ideal microstructure. Selectivity of DPLC process is also confirmed by multiphysics simulation and experiments. The combination effects of pulse numbers and laser intensity to trigger laser ablation are investigated in order to avoid undesired results during multiple laser processing. The number of pulse numbers is inversely proportional to the laser fluence to trigger laser ablation.
Kinetics and thermodynamics associated with Bi adsorption transitions at Cu and Ni grain boundaries113(2013); http://dx.doi.org/10.1063/1.4805361View Description Hide Description
The grain boundary diffusivity of Au in Cu and Cu-Bi, and Cu in Ni and Ni-Bi are characterized by secondary ion mass spectroscopy depth profiling. Samples are equilibrated in a Bi containing atmosphere at temperatures above and below the onset of grain boundary adsorption transitions, sometimes called complexion transitions. A simple thermo-kinetic model is used to estimate the relative entropic contributions to the grain boundary energies. The results indicate that the entropy term plays a major role in promoting thermally and chemically induced grain boundary complexion transition.
Modeling of plasticity and fracture of metals at shock loading113(2013); http://dx.doi.org/10.1063/1.4805713View Description Hide Description
In this paper, we present a model of dislocation plasticity and fracture of metals, which in combination with the wide-range equation of state and the continuum mechanics equations is a necessary component for simulation of the shock-wave loading. We take into account immobilization of dislocations and nucleation of micro-voids in weakened zones of substance; this is distinguished feature of the present version of the model. Accounting of the dislocations immobilization provides a better description of the unloading wave structure, while the detailed consideration of processes in the weakened zones expands the domain of applicability of fracture model to higher strain rates. We compare our results with the experimental data for the shock loading of aluminum, copper, and nickel samples; the comparison indicates satisfactory description of the elastic precursor, unloading wave, and spall pulse. Using the model, we investigate intently the early stage of the shock formation in solids; it is found out that the elastic precursor is formed even for a strong shock wave, and initially the precursor has very large amplitude and propagation velocity.
Efficiency limits for the rectification of solar radiation113(2013); http://dx.doi.org/10.1063/1.4805819View Description Hide Description
Efficiency limits for rectifying (converting AC to DC) incoherent broadband radiation are presented, prompted by establishing a fundamental bound for solar rectennas. For an individual full-wave rectifier, the bound is 2/π. The efficiency boosts attainable with cascaded rectifiers are also derived. The derivation of the broadband limit follows from the analysis of an arbitrary number of random-phase sinusoidal signals, which is also relevant for harvesting ambient radio-frequency radiation from a discrete number of uncorrelated sources.
Thermoluminescence properties of Tl2Ga2S3Se layered single crystals113(2013); http://dx.doi.org/10.1063/1.4807165View Description Hide Description
The trap center(s) in Tl2Ga2S3Se single crystals has been investigated from thermoluminescence (TL) measurements in the temperature range of 10–300 K. Curve fitting, initial rise, and peak shape methods were applied to observed TL glow curve to evaluate the activation energy, capture cross section, and attempt-to-escape frequency of the trap center. One trapping center has been revealed with activation energy of 16 meV. Moreover, the characteristics of trap distribution have been studied using an experimental technique based on different illumination temperature. An increase of activation energy from 16 to 58 meV was revealed for the applied illumination temperature range of 10–25 K.
Medium range order engineering in amorphous silicon thin films for solid phase crystallization113(2013); http://dx.doi.org/10.1063/1.4807166View Description Hide Description
In recent years, it has been recognized that medium range ordering (MRO) in amorphous silicon (a-Si:H) plays a role in controlling its solid phase crystallization (SPC) behavior. Information on the MRO can be obtained from the width of the first X-ray diffraction (XRD) peak of a-Si:H centered around 2θ = 27.5°. The broader the full width half maximum (FWHM) of the first XRD peak, the less ordered the a-Si:H material in the medium range length scale (up to 5 nm). In this work, it was found that the FWHM of the first XRD peak changes with the pressure used during the deposition of a-Si:H. A threshold SPC behavior was observed as a function of the a-Si:H deposition pressure and a good correlation between the SPC behavior and the a-Si:H XRD peak width was found. Results in this study indicate that higher MRO in a-Si:H led to faster SPC rates and smaller grain sizes, suggesting the presence of relatively active and high density of nucleation sites. High angle annular dark field scanning transmission electron microscopy and ultraviolet reflectance indicate that films with higher MRO yielded polycrystalline silicon (poly-Si) grains which were more defective and non-columnar in morphology. Results suggest that a-Si:H material with lower MRO were preferred as a precursor for SPC, which forms a better quality poly-Si thin film material. It was proposed that ion bombardment seems to play a role in altering the a-Si:H properties.
On the structural stability of CeN at high pressures: Ab initio calculations113(2013); http://dx.doi.org/10.1063/1.4803884View Description Hide Description
The structural stability of CeN under hydrostatic compression has been analyzed theoretically. The comparison of enthalpies calculated as a function of hydrostatic compression for rocksalt type (B1), tetragonal (B10), and CsCl type (B2) structures suggests that the B1 phase will transform to B10 structure at ∼53 GPa, which upon further compression will transform to B2 phase at ∼200 GPa. However, the static high pressure energy dispersive x-ray diffraction measurements on CeN by Olsen et al. [J. Alloys Compd. 533, 29 (2012)] report that the B1 phase transforms directly to B2 phase at ∼65 GPa. To resolve the discrepancy between our calculations and experimental results, we have performed lattice dynamic calculations on these structures. The phonon spectra calculated at zero pressure correctly show B1 phase to be dynamically stable, and B10 and B2 to be unstable. At 60 GPa, the B1 phase becomes dynamically unstable and the B10 structure emerges as a dynamically stable phase whereas B2 still remains unstable. At still higher pressure of ≥200 GPa, the B2 phase becomes not only the lowest enthalpy structure but also dynamically stable. These findings support the results of our static lattice calculations. Further, our calculated angle dispersive x-ray diffraction pattern of B1, B10, and B2 phases shows that most of the diffraction peaks of B10 phase except few weak peaks coincide with the peaks of either B1 or B2 phase; which may pose a difficulty in unambiguously identifying the high pressure phase until a sufficient amount of B1 phase is transformed to the new structure so that the weak peaks, if present, are also visible.


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on January 24, 2013 - 9:50 PM
LOCKPORT – A North Tonawanda sex offender admitted in Niagara County Court Thursday that he violated his probation last month by having sexual contact with a 17-year-old boy.
At sentencing March 21, Robert W. Miller, 37, of Oliver Street, will receive no more than four years in prison and 10 years of post-release supervision. County Judge Matthew J. Murphy III said.
Miller also will have to plead guilty in North Tonawanda City Court to a sexual misconduct misdemeanor, Assistant District Attorney Robert A. Zucco said.
Miller was placed on probation in December 2009 after pleading guilty to first-degree sexual abuse for molesting a 14-year-old boy in North Tonawanda in 2008.


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"She tried to support him as much as she could, but at the end of the day she realized it wasn't best for her and her children (to stay)," someone close to Spears tells PEOPLE in its upcoming cover story. "She's standing up for herself and making positive changes in her life." (The couple have two sons: Sean Preston, 1, and Jayden James who was born on Sept. 12.)
Rumors of a Brit split were rampant: The couple hadn't been photographed together in weeks, and Spears skipped several recent events to promote Federline's album Playing with Fire. Still, the timing took many by surprise.
"As far as I knew they were perfectly fine," says Michael Prescott, a family friend from Kentwood, La., Britney's hometown. "I talked to Miss Lynne (Britney's mother) just the other day and she said Britney and Kevin were going to take a vacation trip together to Hawaii, just get away from everything for a few days."
The announcement "came as a total surprise," says a Federline pal. "We're all in shock. (We're hoping) it might just be that she's feeling a lot of postpartum emotions and this is something that will blow over."
Complete Britney Coverage
By the time a solo Federline arrived in Toronto Monday "he looked pretty depressed," says a photo agency rep who was with him.
Spears, on the other hand, had never looked happier. On Monday she dropped in on David Letterman at the Late Show looking svelte and wearing a short black dress and blonde bob.
After the appearance Spears went straight from the Ed Sullivan Theater in midtown Manhattan to the nearby Sony Studios, where she faxed her signature to the Los Angeles lawyers handling her divorce. The next day, Nov. 7, the lawyers filed divorce papers at the L.A. county superior court.
Though the couple's two-year marriage always seemed a little shaky (one Web site started a divorce countdown the day after their September 2004 wedding), a source close to Federline says the marriage took a turn for the worse in late September when Federline headed to Las Vegas with his friends to party at Tao for the nightclub's one-year anniversary, leaving Britney, who had just given birth three weeks earlier, home alone.
"This was her last straw," says the source. "He said, 'I have to go to Vegas.' He didn't have to go to Vegas. He uses any excuse to party. She said, 'I've had enough.' "
Not long after that, according to the source, Federline moved out, and has been staying with friends who have a place in the San Fernando Valley.
For more on Kevin and Britney's split, pick up PEOPLE, on newsstands Friday. Subscribers can also read the complete cover story online here.


text: quote: I remember the exact instant when computer hardware became a commodity. Steve Jobs got up in front of one hundred journalists and in less than 60 seconds, a million Apple zealots went from ardent Intel naysayers to hardened Intel devotees. In that moment I realized it didn't really much matter to anyone which CPU was better than another, it only mattered what Steve Jobs told everyone to think anyway.


text: Jajja's Kids: Addressing the Needs of Ugandan Street Children Posted on October 25, 2012 by rpcvneny 0 Jajja's Kids Addressing the Needs of Ugandan Street Children Save the Dates! Dear Friends, Exciting things are happening for Jajja's Kids!! A month following my trip to Uganda this past summer, Ronnie Sseruyange–my "adopted" Ugandan kid–came to the U.S. for a three month visit. He's currently an Education Volunteer at Heifer International's demonstration farm in Massachusetts. And Ronnie will be at Two Events sponsored by Jajja's Kids: Meet and Greet Saturday, October 20, 9 am – 1 pm Hear Ronnie talk about life in Africa, show photos, and play his drum! Location: Troy Farmers Market River Street, Troy Click here for directions Uganda Starts with U… Sunday, October 28, 3 pm – 6 pm To raise awareness and support for Jajja's Kids… Featuring Ronnie and Special Guest Lee Shaw Traditional African Crafts, Music and Food And a Silent Auction Location: Woman's Club of Albany, 725 Madison Avenue, Albany, NY (Food from 3 to 4 pm) Suggested Contribution: $25 – 40 Hope to see you in October! – Diane Reiner Jajja's Kids ~ P.O. Box 1425 ~ Latham, NY ~ 12110 email@example.com (518) 588-0651 Share this:TwitterFacebookLike this:Like Loading... Related


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Holiday How-To: Thanksgiving Crafts and Pumpkin Recipes
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How to Make Thanksgiving Kids Crafts that Look Good Too
By: The Editors of Favecrafts.com
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Anyone who has little ones in their life can agree that kids' arts and crafts projects are a treasure no matter how it actually looks. Kids can do no wrong, when it comes to crafts, right?
If you're being totally honest, you may have at some point, decided not to put Junior's homemade papier mache turkey in the center of the table for Thanksgiving dinner. That doesn't make you a bad person. Often times kids' crafts are just different than serious, beautiful DIY home décor. You love them both for different reasons.
Here are a few ideas on how to make Thanksgiving kids' crafts that look good too! You never knew Thanksgiving craft centerpieces could be kid-friendly. I advise, from personal experience, that you stay away from the crayon box if you want these crafts to turn out better than expected. While we love the scribbles of a young artist, we can just leave those on the fridge for the time being. Starting out with some colored felts makes the job of "staying in the lines" a non-issue. Colored felt also cuts cleaner than regular construction paper, so half the battle of looking cleanly cut is already won.
Something basic like a Turkey Table Accent is a fun craft to make with kids and yet festive for the holidays. You can set it in the center of the table with pride that you and your child made it together. And it's an easy Thanksgiving craft to make. The method of using a hand as a template for a Thanksgiving turkey is not a new one. In fact, your children have probably already done this craft at school many times over. However, slipping the turkeys together to make a larger, fuller turkey centerpiece may be a new twist on an old craft. Since each person in your family has a different sized hand, make several turkeys and make them represent each family member. Your kids will get a kick out of eating dinner with their little mini-me turkey as the centerpiece. With the soft felt accents that create colorful turkey feathers, this thanksgiving craft project for kids is a keeper.
Turkey Table Accent
- 1 - Cocoa EZ Felt Sheet, 12 x 18
- 1 - Red Soft Felt Sheet, 9 x 12
- 1 - Tangerine Soft Felt Sheet, 9 x 12
- 4 - 3/8" Diameter Google Eyes
- Fabric Glue
- Scissors
- Trace around your child's hand onto a piece of Cocoa EZ Felt twice.
- Cut out hands from EZ Felt Sheet.
- Cut corresponding slits on each felt hand. One hand will have a slit going from the middle finger to the center of the palm. On the other hand, the slit goes from the bottom of the palm to the center point of the hand.
- Glue google eyes onto the thumbs of the hands. This will be your turkey's head.
- Cut 8 Feather Shapes each from the Red and Orange Soft Felt Sheets. Also cut an oval shape from the Red Felt.
- Glue feathers and oval to the turkey like shown above. Repeat for the other side. You will have to recut the slit from Step 3 on one of the hands.
- Slip together.
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text:
Over the last several weeks I have received calls from some World All Star calibur players and coaches regarding our "Lacrosse Economy".
I believe this to be a bit worse at the moment than our regular economy.
People in everyday life are struggling. Struggling for jobs, family and overall strength.
For the laxers, a lot of companies that were on board or on the cusp of investing into the game have silenced their pocketbooks.
For the "inventors" of great ideas that require capital, have had to temporrily table their coming out party for a short spell.
Players and coaches alike need to take this time and really search their souls as to what they would like to be in our game.
Last I heard, push ups, sit ups and wall ball were still free. The Internet clinics were also minimally priced to the tune of your connection fee and of course, faith is free.
The economy will turn around as it always has. Where will you, your skills, your coaching and your faith be at that time?
Lee E. Southren
Acorn Financial
Faceoff Sports Management, LLC


text:
We will never rent or share your email, period.
This year we are organizing our teaching emails into four important Buddhist topics for contemplation: Our Precious Human Life, Impermancence, Karma or the Law of Cause and Effect, and the Nature of Samsara. These teachings are fundamental to all Buddhist traditions and reflection upon them provides the foundation for your meditation practice.
Everything in the universe is changing in each moment. The seasons change; day changes to night. Children become adults; adults grow old. Since everything is constantly changing, we never know when the end will come. We may be perfectly healthy today, but it is possible that tomorrow we will die. If we want to practice Buddhism then we must do it right now. We cannot wait for a tomorrow that may never come. By contemplating impermanence, we cultivate diligence in our practice.
The Buddha taught that every action of our body, speech and mind leaves an impression on our personal continuum which will eventually ripen and produce a result. This is called the Law of Karma, or the law of cause and effect. Generally, wholesome actions will produce wholesome results and unwholesome actions will produce the opposite. By studying the teachings on karma we learn which actions to adopt and which actions to abandon in order to create the causes which will produce happiness for ourselves and others.
Samsara means "wheel of life". Buddhism teaches that driven by our karma, we cycle through endless rounds of birth, life, death, and the intermediate stage called the "bardo". The nature of samsara is suffering. Even pleasure is ultimately suffering because it is impermanent. By contemplating the nature of samsara and acknowledging the pain and suffering of our lives, we are motivated to seek liberation. We begin to wonder whether worldy desires are really worth clinging to, and a sense of renunciation begins to develop in our minds.
Order any time: 800.794.9862 . FAX 978.620.1352 . www.dharmacrafts.com Contact Customer Service©2000 - 2016 DharmaCrafts, Inc.


text:
The Department of History Graduate Student Association (DOHGSA) is pleased to announce our 13th annual graduate student conference.
The conference theme is "Among Four Shores: Change and Exchange in the Atlantic World," highlighting the interplay and exchange of ideas, people and commodities between the Atlantic continents. Papers focusing on other topics may be considered on their merits.
The keynote speaker for this conference will be Professor of History Andrew C. Isenburg from Temple University. His research focuses on environmental history, the history of the American West, and the history of encounters between settlers and natives in North America. His current biographical work, Wyatt Earp: A Vigilante Life, is due to be released in the summer of 2013.
We encourage a diverse group of participants to present their work and we are interested in papers which employ a variety of disciplinary or methodological approaches to Atlantic history. For this year in particular, we are especially interested in papers from an environmental history perspective. We are also seeking graduate students willing to serve on discussion panels.
All paper and panel proposals must be submitted no later than February 23rd, 2012.
Paper Proposals
Please limit your proposal to a 300 word abstract. This proposal should include a working title and a brief description of the topic to be discussed, including a clear statement as to the central thesis of the paper. Each application should be accompanied by a current curriculum vitae.
Panel Proposals
Please include a single page description of the envisioned panel topic. Each submission must include a panel title, a list of proposed panelists with their contact information, a brief description of the purpose and theme of the panel, a one-paragraph abstract of each of the papers, a one-page curriculum vitae for each panelist, commentator and chair.
Everyone selected for participation in the Conference must submit a final paper by March 15, 2012.
Send proposals and questions to firstname.lastname@example.com. For the most up-to-date information on the conference, please visit the DOGSHA website at: http://clubs.fiu.edu/dohgsa.
The conference will be held at Florida International University's Modesto A. Maidique Campus located in Miami, Florida. Department phone number: (305) 348-2328.
Department of History
Florida International University
Modesto A. Maidique Campus
Miami, FL 33199


text:
Cooley Dickinson Hospital does not retain copies of birth certificates. Copies of birth certificates are obtained through the City of Northampton's Office of the City Clerk.
Certified copies cost $15.00 each. Payment may be made in cash, money order or bank check. Personal checks no longer accepted. Make checks payable to City of Northampton. If requesting documents by mail, please include a self-addressed, stamped envelope. Either bring or send your request form to the City Clerk's office, 210 Main Street, Northampton, MA 01060.
All vital records must be requested in advance. No same day service.
To help prevent identity theft, as of January 1, 2009, all vital records will be issued on security paper. Security paper prevents photocopies from being made.
Office of the City Clerk
Wendy Mazza, City Clerk
210 Main Street, Room 4
Northampton, MA 01060
Office Hours: 8:30 a.m. - 4:30 p.m. Monday - Friday
Telephone: 413.587.1224
Email: firstname.lastname@example.com
Website: http://www.northamptonma.gov/cityclerk/
Cooley Dickinson Hospital • 30 Locust St. (Route 9), Northampton, Mass. • (413) 582-2000


text:
Welcome to the Quaron S.A.S. website
|Quaron S.A.S is a leading company in the distribution of high quality chemicals in France. Its strong points are Quality, Safety and Respect for the Environment.
The main distribution sites are in:
• Rennes
• Montereau (South Paris)
• Cestas (Bordeaux)
• Niort
• Lille (Haubourdin)
• Formerie (Rouen)
• Arnas (Lyon)
This network enables us to offer you a complete package and recognised responsiveness. We have a storage capacity of more than 11,000 m3 enabling us to meet your needs throughout France, Europe and North Africa.
The Group:
Since 2011 Quaron S.A.S. has been owned by the German chemical distributors, Stockmeier (www.stockmeier.de) and Overlack (www.overlack.de). Synergies with our shareholders enable us to meet our customers' needs in most European countries.
In addition to our distribution business Quaron S.A.S has become a specialist in the manufacture of formulated hygiene and disinfection products in various fields such as the agrifood business, local authorities, agriculture, vehicle cleaning, etc. Please visit our Hygiene and Disinfection page: click here.
Quaron, throughout France
Quaron, throughout France and worldwide
Quaron commitments
Quaron commitments
Quaron product
See the Quaron product range


text:
Quality Education in the Benedictine Tradition
July 17, 2012
A special presentation of The Chief by Rob Zellers and Gene Collier about Art Rooney, Sr., the legendary founder and owner of the Pittsburgh Steelers, will conclude the 2012 season of Saint Vincent Summer Theatre from Thursday, July 26 to Sunday, August 19 – concurrent with the 47th annual Pittsburgh Steelers summer training camp at Saint Vincent. "We are grateful that arrangements could be made to bring this wonderful show to the summer home of the Pittsburgh Steelers here at Saint Vincent," commented Br. Norman W. Hipps, O.S.B., president of Saint Vincent College. "We look forward to welcoming thousands of theater and sports fans to campus this summer." Arrangements for the special production were made by Saint Vincent with the assistance of Mr. Rooney's son, Art Rooney, Jr., a 1957 graduate of Saint Vincent. "Gene Collier and Rob Zellers have gathered the wonderful stories that Dad used to tell. They organized them into a play, The Chief," Mr. Rooney commented. "No one in the Steelers family ever called Dad 'The Chief'…the media loved the title. My Dad was not very good at making a speech before a large gathering. He would be very structured and formal. It would always be short and sweet, just the facts. On the other hand, when he was speaking to one to five people, he would be relaxed and animated. He had timing and a sense of wit. He loved irony. Mr. Collier is truly a gifted humorist who can work magic with anecdotes. Mr. Zellers is a master of dialogue and stagecraft. Together they have created a masterpiece. My advice to the actor who portrays Dad is to play it as if he were talking to a small group…breathe life into Gene's and Rob's words. Just let it flow…it will be great!" "To me, the play was like 'going home,' to hear Dad share his stories," Mr. Rooney concluded. "I know that all of the people who visit Saint Vincent will feel as I do…'going home.'" Saint Vincent has chosen SVST stage veteran Philip Winters, assistant professor at Point Park University, to play the title role. Mr. Winters, who is well-known to Saint Vincent audiences for his performances in The Ladies Man, Is He Dead?, and Moonlight & Magnolias, works regularly on the Pittsburgh and regional stages as an actor and occasional director. He has been featured at the Playhouse REP, Pittsburgh Public Theatre and Pittsburgh Irish and Classical Theatre among many others. Recently, Mr. Winters was seen as Mickey in the regional premiere of Mojo at the Playhouse REP, as George in the REP's production of That Championship Season and as Marshall in the Pittsburgh Public Theatre's production of The Little Foxes by Lillian Hellman. In addition to his work in the classroom and on the stage, Mr. Winters has been featured in many film and television roles, as well as on radio for numerous voice-over performances. Mr. Winters earned a bachelor of arts degree in English at the University of Pittsburgh and master of fine arts degrees in acting from the University of Connecticut and in theatre arts from Point Park where he teaches acting, voice and speech, theatre history, improvisation and experimental theatre. He is a member of the Actors' Equity Association, SAG, AFTRA, Michael Chekhov Association and VASTA. Saint Vincent Theatre Artistic Director Colleen Reilly will direct the production. "This dazzling, funny and moving play will delight Pittsburgh Steelers' fans...and everyone who loves good stories that are well-told," Ms. Reilly commented. "The year is 1976 and Art Rooney, Sr., the legendary founder of the Steelers organization, sits in his office, reminiscing. He recalls his colorful upbringing in Pittsburgh's First Ward, his years as a boxer and baseball player, his associations with politicians, gamblers and bootleggers. And, of course, he talks about the Steelers: from the team's humble beginnings through the decades of setbacks and struggles, culminating in the championship-winning Steelers of the 1970s – one of the finest teams the game has ever seen. Along the way he spins a colorful American saga – full of faith, love, laughter and some of the most unforgettable characters you will ever meet. Spend an evening with the Chief and we think you'll agree – there's no better company." When the play debuted at The Pittsburgh Public Theatre in 2003, it broke all previous box office records for single ticket sales and attracted a new audience that filled the O'Reilly Theatre as well as more traditional theatergoers. A feature film based on the play was released nationwide in 2010 and has been described as "a rich, inspirational piece of Americana." A preview performance is scheduled at 8:10 p.m. Thursday, July 26. Performances are at 8:10 p.m. July 27-28, 31, August 1-4, 7-11, and 14-18. Three matinees are scheduled at 2:10 p.m. Sunday, August 5, Wednesday, August 15 and Sunday, August 19. Saint Vincent Summer Theatre patrons are asked to make ticket reservations in advance because seats are reserved at all performances except Thursday evening preview shows, which are general admission. Reservations may be made by calling the theater box office, 724 537-8900, or online at www.svst.org. Individual tickets are $10 for preview performances, $19 on Tuesday, Wednesday or Thursday evenings, $22 on Friday and Saturday evenings and $16 for matinees. Special theatre party group rates apply to groups of 20 guests or more. Senior citizens, 62 or older, are eligible for a $2 discount upon request on Tuesday, Wednesday and Thursday evenings only. In addition, student tickets are available for $10 for any seat, any performance. Saint Vincent Summer Theatre performances are all scheduled in the comfortable, air-conditioned Performing Arts Center of the Robert S. Carey Student Center on the Saint Vincent College campus. Free van shuttle service is provided to and from the spacious and convenient parking areas adjacent to the Saint Vincent Basilica. Saint Vincent Summer Theatre will continue to feature its well-known cabaret, the special after-the-show party to which all theatre patrons are invited. Saint Vincent students serve snacks, hot dogs and beverages after the production and also provide entertainment. The cabaret is open after all performances except Thursday preview shows and all matinees. Theatre officials encourage donations if patrons enjoy themselves at the after-the-show party.
Photo: Philip Winters
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