text:
Phoenix suburb plans entertainment district
PHOENIX — Chandler city officials want to turn the city into a major hub in the East Valley by building a retail and entertainment district.
City developers plan to build the center on an empty 4.6-acre lot near Chandler Boulevard and Arizona Avenue.
"We're looking for a developer to come in and put some retail, restaurant and entertainment uses, as well as a hotel on the site," said Kim Moyers, the city's downtown redevelopment manager.
The vacant lot is owned by the city. Moyers said that means less red tape for contractors.
"We'll be able to handhold them along the way and give them expedited review processes so that we can get the dirt moving as fast as possible," she said.
Moyers said she hopes the new entertainment district will draw in more visitors to the city.
"What is neat about downtown Chandler is it's not only for the residents, but it's also for the visitors," she explained.
She added that she wants Chandler to become one of the Valley's top tourist destinations.
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Share your experiences with the Select Staffing Santa Barbara International Marathon & 1/2 Marathon below Back to event details page.
Worst race event ever!!! It was poorly organized from start to finish. I signed up for this event because it was going to be held in this beautiful city and would have great views along the way. Although the views were okay my experience was horrible. The expo was mediocre to say the least. The shuttle buses to take people from UCSB to race start were late or didn't have enough of them. People stood outside for over an hour to get on. Once I got on the shuttle bus we headed to race start and the bus stopped a half mile from the start. The race had already begun and the runners were running toward us. We were told to get off and walk to the start. We had to dodge runners drop off our check-in bags on the grass because the vehicle with the check-in stuff had already left. Another vehicle would take the check-in stuff to the race finish. During the run there wasn't enough water or Gatorade. After the race I went to pick up my check-in bag to find out that my down vest that was sealed in the bag was not inside my bag. I ask the staff and their response was, "I have no idea where it is." I walked toward a pile of jackets that were laying on the grass and by chance found it. This was the worst race event experience ever. I will not recommend this race to anyone. I wouldn't even give a one star rating but have to put it on a rating scale.
ACTIVE is the leader in online event registrations from 5k running races and marathons to softball leagues and local events. ACTIVE also makes it easy to learn and prepare for all the things you love to do with expert resources, training plans and fitness calculators.

subset: commoncrawl


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Bertie Oswalt Gilliam Marlow
Published: Thursday, January 29, 2004 at 3:30 a.m.
Last Modified: Wednesday, January 28, 2004 at 11:00 p.m.
ANNISTON | Bertie Oswalt Gilliam Marlow was born September 27, 1904 in Tuscaloosa County, Alabama and died January 28, 2004 in Anniston, Alabama. She married John Elmer Gilliam and had two sons. She later married Grady Marlow and they moved to Birmingham, Ala. In 1996 she moved to Anniston, Ala. to live near her son. She made her home at the NHC Nursing Home.
She was preceded in death by parents, William and Docia Oswalt, three brothers, Cleland, Carl and Covin, sister, Rosa Fondron; and son, William Lonnie Gilliam.
She is survived by her son, Gradus Willard Gilliam of Anniston; stepsons, Charles Ray Marlow and Roy Marlow; 12 grandchildren, 17 great-grandchildren and 6 great great-grandchildren.
The visitation will be Friday, January 30, from 8 a.m. until 9 a.m. at Elmwood Chapel. The funeral service will follow visitation at 9 a.m. at Elmwood Chapel with burial in Elmwood Cemetery. Ridout's Elmwood Chapel, 205-251-7227, is directing.
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.
Comments are currently unavailable on this article


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More media releases
Visions website
More from the studio
While management responsibilities are a fact of life, the core business of school leaders must be the facilitation of teaching and learning, argues Professor Stephen Dinham from the University of Melbourne's Graduate School of Education.
The largest survey of leadership in Australia, the Study of Australian Leadership (SAL), launches today revealing significant shortfalls in business performance, innovation and leadership development in organisations across the nation.
New research out of the University of Melbourne suggests that when it comes to good leadership at the Olympic level, age trumps physical stature.
Knowledge leaders need better institutional support to effectively apply management research and successfully drive innovation and change within organisations, a new study has found.
Australian workers believe their workplaces suffer from poor leadership and need better management, according to a survey into workplace management by the Centre for Workplace Leadership at the University of Melbourne.
The Australian Vocational Education and Training (VET) sector needs strategies for managing the looming leadership succession crisis, according to a new report
Australia has a vital role to play in the region in campaigning against the death penalty, says Fr Peter Norden AO. "I dont think it's enough for Australians to say it's not an issue in this country. We are based in a region where many countries execute their citizens and we are host to many overseas students studying in Australia from these countries."We need to engage with those students while they are studying here to be more creative in their thinking, because they're going to be the leaders in those countries when they return.""We need to engage them in dialogue and conversation. In their own countries many of them aren't even allowed to discuss this issue; there's no freedom of the press, there's no open discussion, they're too scared to sign petitions. Fr Norden, a Vice Chancellors Fellow at the Melbourne Law School, will be one of a number of key speakers at a rally tomorrow at the State Library as part of the International Day of Action Against the Death Penalty, organised by the World Coalition Against the Death Penalty. Final year Melbourne Law School student and Social Justice rep Alan Wu, barrister Julian McMahon Reprieve Australia President Rachel Walsh will also speak at the event.
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text:
I had a chin implant (inserted through chin) a week ago. I have had a completely numb lower lip since then. I was told this was normal and it will come back. Today my lip has been twitching the whole day. Is this a sign perhaps the nerves are healing and I will get some feeling back soon?
Is Numbness and Now Twitching Normal in Lower Lip After Chin Implant?
- NewNoseNYC
- 5 years ago
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text:
a wheel free to rotate about its axis that is not frictionlessis initially at rest. A constant external torque of 50Nm is appliedto the wheel for 20 sec, giving the wheel an anguler velocity of600 rev/min the external torque is then removed and the wheel comesto rest 120sec later .
a.the moment of inertia of the wheel
b.the frictional torque , which is assumed to beconstant.


text:
All Thanksgiving Cookware
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On one of my blogs I noticed there was an upgrade available so I downloaded and and installed it over my 2.7 version.
I went to 'Tools', then 'Upgrade'. I chose the Nightly Build version to download.
When I was done, I ended up with this version - WordPress 2.8-bleeding-10187.
Anyone have this version and notice any differences? I don't. My RSS feeds on the Dashboard are still not updated and everything else looks the same.


text: Posted December 28, 2010 Not sure yet. I am waiting to see who our new HC is before I decide. I think JR hires another defensive minded run out the clock coach. If so, trade down for Fairley, pick up a second rounder and pick up best available WR. I am not so certain Moore or Clausen are not good enough to be game managers. If we go defensive minded again, I really hope we give a hard look at Ron Rivera... He is capable of running the 3-4 but he has ran the 4-3 in Chicago.. He could also bring with him John Ramsdell, who is the QB coach for SD who has developed guys like Phillip Rivers and Kurt Warner, just imagine what he would do with a guy like Luck. Share this post Link to post Share on other sites


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Book your room at Pousada do Capitão
Get an overview of this hotelFamily-friendly pousada with outdoor pool and bar/lounge
Collect 200 points
Simply enter your Nectar card number when prompted. Your points will be credited 30 days after you return from your trip.*Offers may apply
This family-friendly Ilhabela pousada is located by the ocean, just steps from Ilhabela Port Marina and Itaguacu Beach. Engenho D'agua Beach and Itaquanduba Beach are also within 5 minutes.
Property Features
This pousada features an outdoor pool, a bar/lounge, and a spa tub. Free WiFi in public areas and free self parking are also provided. Other amenities include a sauna, massage/treatment rooms, and an arcade/game room.
Room Amenities
All 21 rooms provide free WiFi, pillowtop beds, and cable TV. Guests will also find minibars, hair dryers, and phones.Would you like to give us feedback? Share it! Opens in a new window
Pousada do CapitãoAv. Almirante Tamandaré, 272 Ilhabela Ilhabela SP 11630000
Hotel Amenities
Hotel Amenities
In addition to an outdoor pool, Pousada do Capitão provides a spa tub and a sauna. Public areas are equipped with complimentary high-speed wireless Internet access. A bar/lounge is on site where guests can unwind with a drink. This family-friendly pousada also offers a library, an arcade/game room, and a garden. Onsite self parking is complimentary.
- Free WiFi
- Arcade/game room
- Total number of rooms - 21
- Bar/lounge
- Front desk (limited hours)
- Library
- Spa treatment room(s)
- Free self parking
- Sauna
- Garden
- Spa tub
- Outdoor pool
Family Friendly Amenities
- Family Hotel
- Outdoor pool
- Free Wi-Fi
- Rollaway/extra beds available
- Arcade/game room
- Cribs/infant beds (complimentary)
Available in all rooms: Free WiFi
Available in some public areas: Free WiFi
Free self parking
Room Amenities
- Air conditioning
- Phone
- Minibar
- Bathrobes
- Hair dryer
- Rollaway/extra beds available
- Cable TV service
- Free WiFi
- Connecting/adjoining rooms available
- Free cribs/infant beds
- Pillowtop mattress
Nearby Things to Do
An outdoor pool and a spa tub are on site. Other recreational amenities include a sauna.
The recreational activities listed below are available either on site or nearby; fees may apply.
- Sailing nearby
Hotel Policies
Check-in time starts at 2 PM
Check-out time is noon
Payment types
- Pets not allowed (service dogs only)
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
Only service animals are allowed
Service animals exempt from fees/restrictions
- Resort fee: 10 percent of room rate
Optional extras
- Rollaway beds are available for an additional fee
Hotel Name
- Plaza Inn Pousada Do Capitao Ilhabela, Brazil
- Pousada Capitão
- Pousada Capitão Ilhabela
- Pousada Capitão Pousada
- Pousada Capitão Pousada Ilhabela
We should mention
Parents or a legal guardian traveling with children under 18 years must present the child's birth certificate and an identity card with photo (passport, for example) at the check-in. For international travels from Brazil, if just one of the parents is traveling with the child, she/he must present – in addition to the child's certificate of birth and identity card with photo – a letter authorizing the trip signed by the other parent with a notarial certification of signature. In case the parents or the legal guardian, as applicable, cannot or are unwilling to give this authorization, a judicial authorization is required. People who intend to travel to Brazil with children must consult with the Brazilian consulate before traveling for more information. One child 5 years old or younger stays free when occupying the parent or guardian's room, using existing bedding. The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.


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This is the popular Deuces Wild video poker game with a strategy analysis engine built-in to help you train to become a better player. After each hand is dealt, the strategy engine calculates all possible outcomes to determine the best cards to hold to get the highest payoff. You can click 'Hint' to view the results or you can play without hints. If you did not hold the optimal cards, a popup message will inform you of the error and you will see which cards were optimal. Click 'Pay' to show a payout odds table of all possible hands. Statistics on the number of errors you make will be tracked as you improve your play.
Special Features:
Hint - Tells you which cards to hold
Payout Odds Table - shows every possible hand and payout odds
Strategy Check - Informs you if you did not hold the right cards
Statistics - Tracks how well your are playing
Log File - tracks all your plays so you can review later
Strategy assumes maximum bet. This game is for entertainment purposes only. No guarantee of strategy accuracy.
Feel free to email if you have any issues. If you believe you have found a strategy error, please take a screen shot of the payout odds table for that hand and send me a copy.


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- Report: #809939
Report - Rebuttal - Arbitrate
Complaint Review: Sonic Electronix
Sonic Electronix28340 Ave Crocker Valencia, California United States of America
Sonic Electronix Sent phony or invalid tracking # for shipment, and will not answer their phone. Valencia , California
*UPDATE Employee: Sonic Electronix is 100% Legitimate
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This report was posted on Ripoff Report on 12/15/2011 02:35 PM and is a permanent record located here: http://www.ripoffreport.com/r/Sonic-Electronix/Valencia-California-91355/Sonic-Electronix-Sent-phony-or-invalid-tracking-for-shipment-and-will-not-answer-their-809939. The posting time indicated is Arizona local time. Arizona does not observe daylight savings so the post time may be Mountain or Pacific depending on the time of year.
Ripoff Report has an exclusive license to this report. It may not be copied without the written permission of Ripoff Report.
Click Here to read other Ripoff Reports on Sonic Electronix
If you would like to see more Rip-off Reports on this company/individual, search here:Search Tips
In order to assure the best results in your search:
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- Only search one name at a time if Company has many AKA's.
#1 UPDATE Employee
Sonic Electronix is 100% Legitimate
AUTHOR: Sonic Electronix Management - (United States of America)
SUBMITTED: Monday, December 19, 2011POSTED: Monday, December 19, 2011
We don't have specific reference to your transaction but we'd like to address your concern. Your first order was placed on 12/09 as stated in your response. Orders take 24 hours to process once each request is received; that said, since your transaction was placed on a Friday, your merchandise shouldn't have shipped until that following Monday, 12/12. When you received tracking confirmation, that's when your merchandise left our facility. We understand your worry when the tracking number never showed any scans, as on your end, it appeared nothing was ever shipped. However, upon contacting USPS' Consumer Industry Affairs Department (telephone #661-775-6681) in relation to this situation, they've advised that none of their shipments are being scanned, as to allow on-time deliveries during this busy holiday season. For both Priority and Parcel services, this lack of scan is taking place; however, need not worry, as your packages were shipped and are currently in-transit.
These above facts also apply to your second shipment. Although, that package should have been sent on Tuesday with our 24 hour processing delay. USPS specifies their Priority Mail service takes roughly 2-5 business days for delivery, so these shipments should arrive soon, if they're not already in your possession.
Our Customer Commitment Team is available seven days a week by phone and email. Due to the high influx of orders we've received lately, our telephone support delay has been longer than usual. However, we're on the other line ready to assist if your patient enough to wait. Although, if you'd prefer to avoid our hold times, we're available via email at email@example.com. We answer those responses within 24-48 hours.
Every business receives complaints: it's how those situations are addressed that measures the true quality of a service. We've received 57 complaints on the BBB: however, we've responded to every consumers concerns to their satisfaction, or with reasonable effort to earn our A+ rating. We not only maintain that perfect score, but also have high ratings on PriceGrabber, Reseller Ratings, and are a member of Bizrate's Circle of Excellence.
We're certainly sensitive to this situation, although you didn't permit us with an opportunity to explain the circumstances. We hope this reconciles your questions and concerns.
Are you an owner, employee or ex-employee with either negative or positive information about the company or individual, or can you provide "insider information" on this company?
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text:
Pharmacyclics Earns Milestone - Analyst Blog
Pharmacyclics, Inc. ( PCYC ) recently announced the enrollment of the fifth patient in a phase II study that is being conducted with ibrutinib in patients suffering from relapsed or refractory mantle cell lymphoma (MCL). With the enrollment of the fifth patient, Pharmacyclics is eligible to receive a $50 milestone payment from partner, Janssen Biotech, Inc., a Johnson & Johnson ( JNJ ) company.
The single-arm, multi-center phase II study, SPARK (MCL2001), is being conducted in MCL patients who have been treated with at least one prior rituximab-containing chemotherapy regimen and who progressed after treatment with bortezomib. While overall response rate is the primary endpoint, secondary endpoints include overall survival rate, progression-free survival rate, and pharmacokinetic data.
Pharmacyclics and Janssen's agreement dates back to December 2011. The companies are collaborating for the global development and commercialization of ibrutinib. Besides receiving a $150 million upfront payment from Janssen, Pharmacyclics is entitled to receive another $825 million on the achievement of development and regulatory milestones.
With the triggering of the $50 million milestone payment for the SPARK study, Pharmacyclics has already earned $100 million in the form of development milestones. This includes a $50 million milestone payment that was triggered earlier this month with the enrollment of the fifth patient in another study (RESONATE (PCYC-1112)) with ibrutinib.
The international phase III randomized, multicenter, open-label RESONATE study is being conducted in patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL).
We currently have a Neutral recommendation on Pharmacyclics, which carries a Zacks #2 Rank (short-term 'Buy' rating). We are positive on the company's collaboration with Janssen for ibrutinib. Janssen is a suitable partner for Pharmacyclics. Janssen's strong global presence bodes well for the commercialization of ibrutinib, once it is approved.
JOHNSON & JOHNS (JNJ): Free Stock Analysis Report
PHARMACYCLICS (PCYC): Free Stock Analysis Report
To read this article on Zacks.com click here.
Zacks Investment Research


text: I installed this plugin and wrote my first global message, which seemed to work fine, but I just tried to write a second and it doesn't want to work. I click the "Add News" link, type in my title and text, and choose who it should be viewable to, click "save", get the "News item created!" message in the yellow box, but my message isn't shown to anyone (I've logged in as a test user to check), and isn't in the lists of messages to view/edit. I don't see it anywhere :/


text:
Definition of autarch in English:
A ruler who has absolute power: he is one of those pitiable petty autarchs who habitually lord it over children and helpless underlings
More example sentences
- Early in his essay, the editor makes it clear that his warning is against all autarchs.
- It's an anarchic assemblage of petty autocracies with numerous additional charismatic nobles advising the autarchs.
- But in the old Citadel in the enormous city, they still exist: two Masters, some journeymen and the apprentices, all locked up in their tower, doing the biddings of the judges and the autarchs, inflicting pain and ending lives.
Early 19th century: from Greek autarkhos, from autos 'self' + arkhos 'leader'.
For editors and proofreaders
Line breaks: au|tarch
Definition of autarch in:
What do you find interesting about this word or phrase?
Comments that don't adhere to our Community Guidelines may be moderated or removed.
= trending


text:
Product Reviews
I have wasted so much time looking for wedding shoes and I finally realized NO ONE WILL SEE THEM! So I went ahead and bought these from overstock because they were pretty close to what I imagined that I wanted. For the price I was prepared to wear a low quality shoe with cheap details, but I was shocked to find beautiful quality shoes! Everyone who has seen them loves them. These are really bridal shoes, complete with the white shoe bag and fancy little bridal shoe box that they come in. I may have wasted time and money on some parts of my wedding, but this is in the top three best wedding decisions that I made.
- How did the color on site compare with the actual product? same - white
- Please tell us about the quality of the product. good quality shoe, came with satin shoe bag and fancy wedding shoe box.
- How accurate was the sizing? it might run a tiny bit big, but there are little elastic straps in the heel to help them stay on.


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Raw Vegan
Over a year ago
So, I've been a vegan for a little over a year now and I've heard alot about raw food and raw vegan diets. I've heard about the many benifits of them, and I really want to try a raw vegan diet. I'm just not sure I understand the full concept of them. Are their any raw vegans here ? What has your experince been with being a raw vegan, any advice/tips ? 🙂
Please log in to reply.
Over a year ago
Definitely easy when you have a dehydrator. But doable without one. There are some sites I visit http://www.choosingraw.com/ is a good one. I feel you can still get the benefits from raw by devoting a day or two out of the week if you're not used to it. Some of their boutique foods get pretty expensive but if there are vegans who can survive without tofu, I think raw vegans can make it without them.You must be logged in to reply to this topic.
Over a year ago
I tried it for a little bit, and it rocked!! I had so much more energy, and felt perfectly fine on 3-4 hours of sleep! 😀 But sugar affected me big time; I ate a little piece of chocolate, and I felt sick to my stomach (shows raw is good and sugar is bad).
My advice to you is that don't be super-picky. (like using raw nori – heck, I couldn't find them so I stuck with regular toasted ones). And make sure to research beforehand! (like what you can eat, what raw food are available, etc) It's a great way to detox, and I'd definitely try again! (but because it's been hard to eat raw when I'm around my family/friends, I'm nonraw right now. But still, it's well worth your time to try!) 😀 I hope this helps! ^^You must be logged in to reply to this topic.


text:
How do I add it on a self-hosted WordPress site?
Search Engine LandShared publicly -
If you haven't implemented rel=author yet, you should probably do that soon. A new +Searchmetrics study published this week says that about 17% of queries included at least one instance of rel=author within the first 100 search results.
9 comments
+Rich Fisher can you link to the specific thread or answer? I'd love to know too. Thanks!
+Philip J Reed This g+ page links to the site that I used to set mine up. https://plus.google.com/107022061436866576067/posts/NJ3syrZomUz
Thanks for sharing. We're just starting to incorporate this into the standard workflow.
Add a comment...


text:
About us
Our vision is to create technology that makes life better for everyone, everywhere — every person, every organization, and every community around the globe. This motivates us — inspires us — to do what we do. To make what we make. To invent, and to reinvent. To engineer experiences that amaze. We won't stop pushing ahead, because you won't stop pushing ahead. You're reinventing how you work. How you play. How you live. With our technology, you'll reinvent your world.
This is our calling. This is a new HP.
Keep reinventing.
Engineering that amazes
Innovation. It's in our blood. But we don't just create technology — we create technology with a purpose: to make life better for everyone, everywhere.
Leading the way
Dion Weisler
President &
Chief Executive Officer
Chief Executive Officer
Cathie Lesjak
Chief Financial Officer
Ron Coughlin
President, Personal Systems
Enrique Lores
President, Imaging & Printing
Stephen Nigro
President, 3D Printing
Stuart Pann
Chief Supply Chain Officer
Tracy Keogh
Chief Human Resources Officer
Shane Wall
Chief Technology Officer
Antonio Lucio
Chief Marketing Officer
Jonathan Flaxman
Chief Operating Officer
Richard Bailey
President, APJ Region
Christoph Schell
President, Americas Region
Nick Lazaridis
President, EMEA Region
Kim M. Rivera
Chief Legal Officer & General Counsel
The latest
..............HP takes steps to address climate change
..............HP unveils consumer style for modern Professionals with its thinnest and lightest notebook ever.
Investor Relations
..............HP announces fiscal 2015 full-year and fourth quarter financial results.
..............HP awakens a new force with Star Wars™ Special Edition notebook
..............HP named to "Climate A List" in CDP Global Climate Change Report
..............HP ranked #9 on list of happiest companies for young professionals.


text:
Eye Health Center
Illustration copyright 2000 by Nucleus Communications, Inc. All rights reserved. http://www.nucleusinc.com
Blepharitis is an inflammation of the eyelids that causes redness, itchiness, irritation, and scaly skin at the edges of the eyelids. Blepharitis is one of the most common eye problems in older adults.
ByHealthwise Staff
Primary Medical ReviewerKathleen Romito, MD - Family Medicine
Martin J. Gabica, MD - Family Medicine
Specialist Medical ReviewerChristopher J. Rudnisky, MD, MPH, FRCSC - Ophthalmology
Current as ofSeptember 9, 2014
WebMD Medical Reference from Healthwise
Last Updated: September 09, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
© 1995-2015 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
Today on WebMD
Learn about causes, symptoms, and treatments.
Simple annoyance or the sign of a problem?
Symptoms, triggers, and treatments.
Tips for wearing and caring.


text:
The latest movie theater news and updates
January 9, 2004
Paramount Center for the Arts Photos
Scott Seltzer, at the Paramount Center for the Arts, sent in these shots of the restoration work in progress:
Painters at Evergreene Painting Studios working on ceiling canvas
Interior of the theater, with scaffolding
January 8, 2004
Revival for Yeadon Theater Remains Elusive
YEADON, PA — The restoration of the Yeadon Theater is slowly inching along, according to a new report in the Philadelphia Inquirer.
Current plans call for short-term stablization of the theater to begin within the next four months. Stablization efforts would first address the back portion of the Yeadon, which has been exposed to the elements since September 2003, when a contractor demolished the theater's rear wall.
Catlow Theater For Sale
BARRINGTON, IL — 700 seat historic theater with interiors designed by noted sculptor & designer Alfonso Iannelli. Listed on the National Register of Historic Places. Movie business still in operation. Visit the Catlow website or its page on Cinema Treasures for more on the building's history.
Metropolitan Theater To Be Restored
MANILA, PHILLIPINES — The Metropolitan Theater has been slated for restoration following the signing of "a memorandum of understanding" between the city, the National Commission for Culture and the Arts, and the Government Service Insurance System.
According to the Manila Times, "the signatories could not stress enough the importance of the edifice as a national and cultural landmark." Phillipine President Arroyo also noted her "desire for the restoration of the MET to its former grandeur befitting the country's center of arts and culture for the common masses."
(Thanks to Rob Trent for the news.)
January 7, 2004
Colonial Theatre Pics
CANAAN, CT — As a followup to yesterday's story about the Colonial Theatre, Roger Katz sent in a few pics of the theater's restoration. The first shot was taken approximately a year ago (before restoration began), while the other shots were taken within the last few weeks.
Cinema Treasures Named Site of the Week by 'Save the Sameric' Group
Save the Sameric has named Cinema Treasures as the website of the week in its weekly email newsletter:
"A worthwhile break from Movie Theater of the Week for Website of the Week, cinematreasures.org, for daily news & worldwide directory of movie theaters."
Thanks to Howard Haas at Save the Sameric!
January 6, 2004
San Antonio's Last Drive-In Survives and Thrives
SAN ANTONIO, TX — When the Mission Drive-In opened in 1948, it was one of less than 100 outdoor theaters in Texas. By the golden years of the drive-in, the 50s, Texas had more than 500.
The Colonial: Slowly Coming Back to Life
CANAAN, CT — According to a recent report from the Litchfield County Times, restorations are slowly bringing the Colonial Theatre back to life.
Tickets Sales Drop in 2003
Boxoffice ticket sales last year dropped for the first time since 1991, according to a report by tracking firm Exhibitor Relations. During the 2003 season, ticket sales totaled $9.27 billion, compared to $9.32 billion in 2002, a 0.5 percent drop.
January 5, 2004
New Development Threatens West Virginia's Grandest Theatrical Showcase
HUNTINGTON, WV — The Keith-Albee, a Thomas Lamb designed movie palace, has operated continuously since the Depression. The theater still shows first run movies. In the 70s, it was delicately divided into a main auditorium and three small theaters.


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Soon after it opened in 1913, this generously proportioned space in the heart of the theater district became synonymous with vaudeville. Among the luminaries who have graced its boards are Harry Houdini, Will Rogers, Ethel Merman, Judy Garland, Jerry Lewis, Harry Belafonte, Bette Midler, Shirley MacLaine and Diana Ross. Right now, it's home to the wildly popular revival of West Side Story. Note: Since the Palace is run by the Nederlander Organization, audience members can take drinks and snacks to their seats. Snack responsibly!
|Venue name:
|Palace Theatre
1564 Broadway
New York
|Cross street:
|at 47th St
|Subway: C, E to 50th St; N, R to 49th St; 1 to 50th St
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An American in Paris
An American in Paris: Theater review by David Cote The arrival of two big musicals derived from classic 1950s movies located in the City of Light (see Gigi) indicates either a resurgent interest in the early film oeuvre of Leslie Caron or a lack of producer...Musicals Until Sunday October 9 2016Read more


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- Report: #1067668
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Complaint Review: Wen
WenInternet USA
Wen by Chaz Dean 5 charges - got 2 product - charged after cancelling Internet
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its states it is auto ship yes. however out of 5 charges, we received product twice. after cancelling - they then charged us again. contacted mastercard - who have had many complaints about them - and are now in the process of (trying) to be refunded for the product we did not get - and the charges for product that was not shipped after we cancelled.
it is a scam in the sense they hope that you are rich enough to just not care what is charged - and only send you enough cr4p to make you think more is coming.
it is a total scam.
when you call to cancel - demand the name of agent - your account number and make a not of the date. your credit card company needs this info to fight for your money back. trust me.
This report was posted on Ripoff Report on 07/17/2013 07:32 AM and is a permanent record located here: http://www.ripoffreport.com/r/Wen/internet/Wen-by-Chaz-Dean-5-charges-got-2-product-charged-after-cancelling-Internet-1067668. The posting time indicated is Arizona local time. Arizona does not observe daylight savings so the post time may be Mountain or Pacific depending on the time of year.
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Get cozy SMPers, because in order to take in all the pretty in this party captured by Lindsey Gomes, you need to set aside some serious time. With the prettiest Bride I ever did see, streams of gorgeous California sunshine and the sweetest details to soak in, how in the world could you not love every second of this soiree? See so much more pretty here.
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Nuptials involving sweeping embraces are a favorite of mine. All that giddy excitement and joyous celebration packed into a perfect moment between the Bride and Groom; that is what weddings are all about. The love, the happiness, the excitement of it all. And with photographs by Lindsey Gomes to capture each and every twirl...


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Just redid my writing portfolio with the theme and am a big fan.
Unfortunately, my web hosting has always been glitchy and I'm unable to upload files through the dashboard (I've given up trying to fix it and do manual uploads through a client). I'd like to use a logo, but because of this glitchy hosting I'm unable to upload a photo through the Customize page.
Is there a way to code the logo image (with .jpg URL) directly into the style.css?
I'd also like to ensure that this image is a background and still have the Site Title/Tagline text on top.


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I hope there is a quick and easy answer to this question.
I realise that Import-Rss.php in not really developed for syndication. But I need to be able to import a changing a rss.xml local feed file regularly.
The way i would normally do this sort of thing would be to set up a Cron Job. However, the normal way i would normally set one doen not seem to work:
php -f /home/username/public_html/blog/wp-admin/import-rss.php
I have also tried it with the following:
php -f /home/username/public_html/blog/wp-admin/import-rss.php?step=1
Any ideas?
Oh, and yes the rss.xml file is read Ok when I manually go to the import-rss.php file in the browser and use it.
Thanks for your help.
Kind regards


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For some overly complicated reason, throughout gaming, there has been a distant line between the graphical user interface and the user — especially when it comes to typing anything. However, all that changed when Microsoft the introduced the Chatpad, a device which merges the keyboard and controller seamlessly into one.
In this article, I'll be addressing why I can't game without accessories like the Chatpad, and why they're so important to my gaming experience.
Since I've been gaming with the Chatpad, it's no longer a daunting task to type a message, especially when you're in need of the full 140 characters. Personally, I can't game without the Chatpad device around, especially when I'm online. Because, not only is a great device for messaging, it makes using Facebook, Twitter and even navigating the dashboard much easier on the consoles.
I also can't game without any controller in hand. You see, I'm not particularly fond of the keyboard gaming experience; the only possible way I can even game on PC is with a controller. It's funny because I find that the console experience has spoiled me a bit, even if there are more options available when using a keyboard.
In addition to a controller, I also can't game — especially online — without my Turtle Beach Ear Force PX21 headset around. The headset is a universal headset, works on both consoles and PC. The headset rivals any home entertainment system, especially in games like Call of Duty and Gears of War where the sound is an intricate part of the overall experience. This headset is heavy at all and, once you have placed it on, it's like gaming in your own personal space, which is nice if you're living with other people.
These are the three things — the Chatpad, a controller and my Turtle Beach Ear Force PX21 headphones — I can't see myself gaming without. These devices are critical to my gaming experience because they both enhance and give an element of ease when I'm gaming.
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Baked Goods Products:
David's Cookies Chocolate Chambord CakeDavid's Cookies Chocolate Chambord is a rich dark chocolate cake filled with Chambord Chocolate Ganache and Raspberry Chambord liquor flavoring. Learn More$52.991 countQty.
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David's Cookies 10" Chocolate Fudge Birthday CakeDavid's Cookies 10" Chocolate Fudge Birthday Cake is a delicious and moist dark chocolate fudge cake made for that special someone celebrating a birthday. Learn More$52.991 countQty.
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CoffeeForLess baked goods offer you the opportunity to add cookies, cakes, and other baked dessert treats to your coffee order. Treat your home or office to a delicious treat alongside their coffee or tea with biscotti, cookies, and rum cakes from CoffeeForLess. Our variety of baked good offerings allow you to order quality baked goods alongside your regular coffee order of coffee beans, ground coffee, or coffee K-Cups. Indulge your sweet tooth with CoffeeForLess baked goods.


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- Report: #757023
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Complaint Review: Auravie Skincare
Auravie Skincare7900 Gloria Ave, Internet United States of America
Auravie Skincare Unordered product sent and billed!!!! 866 # not being answered, Internet
*Consumer Comment: Auravie Customer Service Number
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This report was posted on Ripoff Report on 07/27/2011 07:21 AM and is a permanent record located here: http://www.ripoffreport.com/r/Auravie-Skincare/internet/Auravie-Skincare-Unordered-product-sent-and-billed-866-not-being-answered-Internet-757023. The posting time indicated is Arizona local time. Arizona does not observe daylight savings so the post time may be Mountain or Pacific depending on the time of year.
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Join us on our 1,100-acre park of rolling hills, original forests and open pastures along the banks of the Yadkin River. You'll enjoy great camping activities like golfing, hiking, horseback riding, swimming, boating, and picnics.
Our RV campground is secluded from the sports activities and playgrounds offered within the park, but also has easy access to any and all of these amenities. If you would like a more luxurious stay, join us at the Manor House Bed and Breakfast, set in a gracefully restored home adjoining our Arboretum and gardens.
- Enjoy Championship Golf on Tanglewood's two award-winning golf courses: the Championship Course, designed by the legendary Robert Trent Jones, Sr., and the Reynolds Course.
- Escape to real life on horseback, on mountain bike or by the lakeside. The park is a true wonderland for whatever your heart desires, because Tanglewood is a place that makes your heart remember it has desires.
- Pet Friendly No need to worry about leaving your four-legged friends at home. Your pets are welcome at our RV Campground. Tanglewood is filled with miles of trails winding throughout the forests, hills and meadows . . . just perfect for a walk with your pet
Rules & Regulations
Tanglewood Park News & Events
Athena's Run 2016
Athena's Run for GYN Cancers will be held at Tanglewood Park on Saturday, September 10th!
Tanglewood's Free Little Library
Come check out Tanglewood Park's Free Little Library!
North Carolina Players Championship!
The 13th Annual North Carolina Players Championship is July 15th-17th!
2016 Aqua Zumba Classes – Tanglewood Aquatic Center
Carolina Pool Management Staff will lead Aqua Zumba Classes (aqua aerobics program with Latin flavor added) at the Peter S. Brunstetter Aquatic Center at Tanglewood Park. Classes will be held Tuesdays and Thursdays from June 13th to August 16th.


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Medford police will sponsor an event to help people safely dispose of unneeded prescription medication and sensitive documents.
The Medford Area Drug and Gang Enforcement team and the Drug Enforcement Administration will accept unwanted medication from 10 a.m. to 2 p.m. Saturday, April 27, as part of National Prescription Drug Take-Back Day. Drugs will be collected in the parking lot behind City Hall, 411 W. Eighth St., Medford.
In addition to the drug take-back event, police have partnered with Rogue Disposal & Recycling Inc. to conduct a free shred event at the same date, time and location. This service allows people to have sensitive documents shredded to help avoid the chance of identity theft.
For details about the drug take-back event, contact Lt. Brett Johnson at 541-774-2260. For additional information about the document shredding service, contact Detective Sgt. Brent Mak at 541-774-2204.
Location, ST | website.com


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Why Doesn't Windows CE Get Any Respect?; When It Comes to Personal Organizers, Microsoft's Minisystem Does Not Rule the Market
By KATIE HAFNER
Published: November 25, 1999
YOU wouldn't expect to find a better spokesman for the Philips Nino than Blake Patterson. If you visit the Philips Electronics Web site, you see a prominent link to a site built by Mr. Patterson, a 27-year-old Web designer from Alexandria, Va. Philips points to Mr. Patterson as a dedicated user of the Nino, the company's palm-size computer. Predictably, Mr. Patterson's site is a veritable shrine to the Nino.
The only problem is that Mr. Patterson has not used a Nino, or, for that matter, any device running Windows CE, the simplified version of Microsoft's Windows operating system, for more than six months. Last summer, he soured on CE altogether and after a brief but happy fling with a Palm organizer, became a fervent early convert to the new Visor from Handspring, a startup that has licensed the Palm operating system. Mr. Patterson, who was once paid by Philips to write about the Nino, has not touched his Nino fan page since late last year and it now hangs, petrified, in cyberspace (nino.philips.com/community).
Meanwhile, Mr. Patterson is busy building a new Web site that is devoted to miscellaneous handheld gadgets. ''I don't think I'll have much positive to say about CE, if I address it at all,'' he said.
As it turned out, Philips wasn't far behind Mr. Patterson. Late last summer, the company decided to drop the Nino from its product line, citing disappointing market growth. The company is still selling the Ninos in stock, said Marty Gordon, a Philips spokesman, which is why the Nino Web page is still up.
When Microsoft first announced Windows CE three years ago (CE does not stand for anything), hardware manufacturers like Philips were quick to start producing handheld devices to compete against the popular Palm organizer, which has its own operating system, called the Palm OS. Industry analysts' projections were so rosy they implied that Palm Computing should run for cover.
But a very different picture has emerged since then. According to NPD Intelect Market Tracking, a research firm in Port Washington, N.Y., personal digital assistants running CE account for just 15 percent of the P.D.A.'s sold; 75 percent run the Palm OS. ''It's not growing at all,'' said Nazia Khaliq, an account manager at NPD Intelect.
Microsoft may be the software giant, but when it comes to Windows CE, it has certainly not stifled competition or gained control of the market. In fact, in the portion of the CE market that consists of handheld organizers, the giant is stumbling.
Just last week, as William H. Gates, the chairman of Microsoft, was at the Comdex trade show, showing off a small new $200 CE-based Internet access device called the MSN Web Companion, another corner of the show was humming with the news that Sony and Palm Computing had signed a deal to work on a new generation of handheld devices using the Palm OS. Soon afterward, Everex confirmed rumors that it would discontinue its CE devices because of slow sales.
Palm's sales, in the meantime, continue to grow, and, with the exception of some serious shipping glitches, Handspring is off to a promising start with its relatively inexpensive Visor.
But as Microsoft is quick to point out, Windows CE is not just for organizers. It is making its way into a variety of products, like digital set-top boxes, game consoles, cell phones, Internet appliances, cars and even automated gasoline pumps. If such products are taken into account, said Rogers Weed, director of Windows CE marketing at Microsoft, sales of CE licenses to various manufacturers are up more than 50 percent for the year, compared with sales at this time last year.
But for pocket-size and larger handhelds, something has not clicked for Windows CE. What is the problem? The answers, from both analysts and consumers like Mr. Patterson, vary widely, but include explanations like these: The price is too high. Microsoft misjudged Palm's momentum. Compared with the relatively simple Palm OS, the CE interface is too difficult to use. The devices are too bulky. The quality is poor. The feature-laden devices promise too much and deliver too little.
Tom Rhinelander, an analyst at Forrester Research, boiled it down to this: CE is too rudimentary to act as a suitable substitute for a real computer and too complicated to run on a P.D.A.
''What Microsoft tried to do was take the entire PC experience and cram it down into a tiny little screen,'' Mr. Rhinelander said. ''Their theory was that people knew and understood Windows and there would be value in retaining the look and feel, and that was absolutely false.''
Chris Shipley, publisher of DemoLetter, an industry newsletter, agreed: ''I don't think you want a Windows computing experience in a palm-size device. You want to look up addresses. You don't want a Start button.''
Another, related criticism is that both the palm-size devices and the slightly larger handhelds, which usually come with a small keyboard, are too packed with capabilities -- that the novelty of downloading video clips and watching them on a tiny screen wears off quickly.


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DALE is nearly ready to face the judges. The Dynamic Augmented Living Environment, Caltech's collaboration with the Southern California Institute of Architecture (SCI-Arc) is now on-site at the Department of Energy's 2013 Solar Decathlon competition site in Irvine, California.
The SCI-Arc/Caltech team has been planning DALE, its unique and completely solar-powered home, since its competition proposal was accepted in January 2012, along with proposals from 19 other American and international teams. Nearly 40 Caltech students participated in the design process, most of which took place in an engineering project course called Introduction to Multidisciplinary Systems Engineering, and offered during the 2012-2013 academic year. Of the students in this course, taught by Melany Hunt, Dotty and Dick Hayman Professor of Mechanical Engineering and a vice provost, seven stayed on, spending their summer actually building the sustainable house.
Once the majority of construction was complete in late September, the SCI-Arc/Caltech team had to pack up DALE and physically move the entire house from its construction site on the SCI-Arc campus in downtown Los Angeles more than 40 miles south to Orange County Great Park in Irvine, where this year's competition will be held starting on October 3.
While some of DALE's competitors had to employ the use of large cranes to transport their entries or coordinate weeks-long international transportation to the competition site, project manager Andrew Gong (BS '12) says that DALE only spent about three-and-a-half hours in transit. "We picked up DALE with a heavy-duty forklift and placed it on long trucks," Gong says. "And there wasn't any damage other than expected small scrapes to the bottom from the forks."
DALE's design consists of two configurable, box-like modules—one kitchen and bathroom module, and one living and sleeping space module—that can move together or apart. When in the open configuration, DALE's design exploits the ambient outdoor temperature to heat or cool the house, helping to maintain a comfortable temperature within the house without using extra energy for heating and air-conditioning. This moving house was designed with sustainability in mind, but the modules also made it easier for team DALE to truck its house down the interstate to Irvine. "Since the house is composed of modules, it was actually fairly simple to pack up and ship. The main issue was just making sure everything got packed on time," Gong says.
The SCI-Arc/Caltech collaboration is one of 20 teams in the Department of Energy competition, each challenged to design and build affordable, attractive, energy-efficient houses that have the comforts of modern living but are powered only by the sun. As the name "Solar Decathlon" implies, teams will compete for the best total number of points in 10 contests. A panel of experts will use the contests to judge and score the entries based on features ranging from architecture and market appeal to affordability and each house's ability to host a movie night—called the Home Entertainment Contest.
The SCI-Arc/Caltech team wants DALE to score well in the overall competition, but the Caltech team members hope they score especially well in one particular aspect: the Engineering Contest. In this contest, a jury made up of professional engineers will judge each house based on the home's functionality, efficiency, innovation, reliability, and project documentation. "In 2011, with CHIP—our first Solar Decathlon entry—we came in second place. With DALE, we took that second place as a challenge," says Gong, "because now we have to get first, obviously!"
To optimize DALE's energy efficiency, the Caltech members of the team spent months calculating and modeling the home's likely energy usage during the competition. Thirty years of Orange County weather data were used to predict heating and air-conditioning needs for the October competition. "The contests are held on different days of the competition, and we based the energy budget on the contests we will have on a given day: the cooking contest, movie night, heating and air-conditioning test, etc.," Gong says. "With our competition energy budget, we then modeled out the performance required from the solar panels to meet that energy demand," Gong says.
According to their calculations, DALE's oversized solar panels will allow the house to be net-zero during the decathlon—meaning it will produce as much energy as it consumes. And in the future, if the house was used in the longer daylight hours of summer, DALE could produce far more energy than it uses, Gong adds.
The SCI-Arc/Caltech team also designed an energy-saving mobile app for DALE that would allow its owner to monitor the home's real-time energy supply and consumption and take steps to use less energy. "As a team, we are aiming to create a house that is not only energy efficient by itself, but also encourages the inhabitants to live a greener lifestyle," Caltech electrical engineering student Do Hee Kim says on the DALE website. "We have made it simple for homeowners to execute these actions by having the ability to remotely turn on and off home appliances," Kim says.
Visitors will be able to interact with DALE and explore its innovative features during public viewings scheduled for October 3–6 and 10–13 from 11 a.m. to 7 p.m. In addition, visitors arriving at 2:30 will get to see the home reconfigured in real time, a feature that sets DALE apart from the other Solar Decathlon entries. The winners will be announced on October 12, and just a few days later, the team will pack up for the move back to Los Angeles. After the competition, DALE will be displayed at the SCI-Arc campus.
And for any house hunters visiting the competition, the SCI-Arc/Caltech team has good news: DALE is for sale and can be delivered to a new owner. Although the Department of Energy provides a limited amount of seed money for Solar Decathlon teams, fundraising is necessary to cover the actual costs of production; funds from the sale of the home will go to recoup some this year's competition costs and could also help support an entry bid for the 2015 Solar Decathlon.
For the third year in a row, the California Institute of Technology has been rated the world's number one university in the Times Higher Education global ranking of the top 200 universities.
Harvard University, Oxford University, Stanford University, and the Massachusetts Institute of Technology round out the top five schools in the 2013–2014 rankings.
Times Higher Education compiled the listing using the same methodology as in the 2011–2012 and 2012–2013 surveys. Thirteen performance indicators representing research (worth 30 percent of a school's overall ranking score), teaching (30 percent), citations (30 percent), international outlook (which includes the total numbers of international students and faculty and the ratio of scholarly papers with international collaborators, 7.5 percent), and industry income (a measure of innovation, 2.5 percent) make up the data. The data were collected, analyzed, and verified by Thomson Reuters.
The Times Higher Education site has the full list of the world's top 400 schools and all of the performance indicators.
A group of researchers at the California Institute of Technology (Caltech) has created the optical equivalent of a tuning fork—a device that can help steady the electrical currents needed to power high-end electronics and stabilize the signals of high-quality lasers. The work marks the first time that such a device has been miniaturized to fit on a chip and may pave the way to improvements in high-speed communications, navigation, and remote sensing.
"When you're tuning a piano, a tuning fork gives a standardized pitch, or reference sound frequency; in optical resonators the 'pitch' corresponds to the color, or wavelength, of the light. Our device provides a consistent light frequency that improves both optical and electronic devices when it is used as a reference," says Kerry Vahala, Ted and Ginger Jenkins Professor of Information Science and Technology and Applied Physics. Vahala is also executive officer for applied physics and materials science and an author on the study describing this new work, published in the journal Nature Communications.
A good tuning fork controls the release of its acoustical energy, ringing just one pitch at a particular sound frequency for a long time; this sustaining property is called the quality factor. Vahala and his colleagues transferred this concept to their optical resonator, focusing on the optical quality factor and other elements that affect frequency stability.
The researchers were able to stabilize the light's frequency by developing a silica glass chip resonator with a specially designed path for the photons in the shape of what is called an Archimedean spiral. "Using this shape allows the longest path in the smallest area on a chip. We knew that if we made the photons travel a longer path, the whole device would become more stable," says Hansuek Lee, a senior researcher in Vahala's lab and lead author on the paper.
Frequency instability stems from energy surges within the optical resonator—which are unavoidable due to the laws of thermodynamics. Because the new resonator has a longer path, the energy changes are diluted, so the power surges are dampened—greatly improving the consistency and quality of the resonator's reference signal, which, in turn, improves the quality of the electronic or optical device.
In the new design, photons are applied to an outer ring of the spiraled resonator with a tiny light-dispensing optic fiber; the photons subsequently travel around four interwoven Archimedean spirals, ultimately closing the path after traveling more than a meter in an area about the size of a quarter—a journey 100 times longer than achieved in previous designs. In combination with the resonator, a special guide for the light was used, losing 100 times less energy than the average chip-based device.
In addition to its use as a frequency reference for lasers, a reference cavity could one day play a role equivalent to that of the ubiquitous quartz crystal in electronics. Most electronics systems use a device called an oscillator to provide power at very precise frequencies. In the past several years, optical-based oscillators—which require optical reference cavities—have become better than electronic oscillators at delivering stable microwave and radio frequencies. While these optical oscillators are currently too large for use in small electronics, there is an effort under way to miniaturize their key subcomponents—like Vahala's chip-based reference cavity.
"A miniaturized optical oscillator will represent a shift in the traditional roles of photonics and electronics. Currently, electronics perform signal processing while photonics rule in transporting information from one place to another over fiber-optic cable. Eventually, oscillators in high-performance electronics systems, while outwardly appearing to be electronic devices, will internally be purely optical," Vahala says.
"The technology that Kerry and his group have introduced opens a new avenue to move precision optical frequency sources out of the lab and onto a compact, robust and integrable silicon-based platform," says Scott Diddams, physicist and project leader at the National Institute of Standards and Technology, recent Moore Distinguished Scholar at Caltech and a coauthor on the study. "It opens up many new and unexplored options for building systems that could have greater impact to 'real-world' applications," Diddams says.
The paper, titled "Spiral resonators for on-chip laser frequency stabilization," was published online in Nature Communications on September 17. Other Caltech coauthors on the study include graduate students Myoung Gyun Suh and Tong Chen (PhD '13), and postdoctoral scholar Jiang Li (PhD '13). The project was in collaboration with Caltech startup company hQphotonics. This work was funded by the Defense Advanced Research Projects Agency; the Caltech's Kavli Nanoscience Institute; and the Institute for Quantum Information and Matter, an NSF Physics Frontiers Center with support of the Gordon and Betty Moore Foundation.
When termites munch on wood, the small bits are delivered to feed a community of unique microbes living in their guts, and in a complex process involving multiple steps, these microbes turn the hard, fibrous material into a nutritious meal for the termite host. One key step uses hydrogen to convert carbon dioxide into organic carbon—a process called acetogenesis—but little is known about which gut bacteria play specific roles in the process. Utilizing a variety of experimental techniques, researchers from the California Institute of Technology (Caltech) have now discovered a previously unidentified bacterium—living on the surface of a larger microorganism in the termite gut—that may be responsible for most gut acetogenesis.
"In the termite gut, you have several hundred different species of microbes that live within a millimeter of one another. We know certain microbes are present in the gut, and we know microbes are responsible for certain functions, but until now, we didn't have a good way of knowing which microbes are doing what," says Jared Leadbetter, professor of environmental microbiology at Caltech, in whose laboratory much of the research was performed. He is also an author of a paper about the work published the week of September 16 in the online issue of the Proceedings of the National Academy of Sciences (PNAS).
Acetogenesis is the production of acetate (a source of nutrition for termites) from the carbon dioxide and hydrogen generated by gut protozoa as they break down decaying wood. In their study of "who is doing what and where," Leadbetter and his colleagues searched the entire pool of termite gut microbes to identify specific genes from organisms responsible for acetogenesis.
The researchers began by sifting through the microbes' RNA—genetic information that can provide a snapshot of the genes active at a certain point in time. Using RNA from the total pool of termite gut microbes, they searched for actively transcribed formate dehydrogenase (FDH) genes, known to encode a protein necessary for acetogenesis. Next, using a method called multiplex microfluidic digital polymerase chain reaction (digital PCR), the researchers sequestered the previously unstudied individual microbes into tiny compartments to identify the actual microbial species carrying each of the FDH genes. Some of the FDH genes were found in types of bacteria known as spirochetes—a previously predicted source of acetogenesis. Yet it appeared that these spirochetes alone could not account for all of the acetate produced in the termite gut.
Initially, the Caltech researchers were unable to identify the microorganism expressing the single most active FDH gene in the gut. However, the first authors on the study, Adam Rosenthal, a postdoctoral scholar in biology at Caltech, and Xinning Zhang (PhD '10, Environmental Science and Engineering), noticed that this gene was more abundant in the portion of the gut extract containing wood chunks and larger microbes, like protozoans. After analyzing the chunkier gut extract, they discovered that the single most active FDH gene was encoded by a previously unstudied species from a group of microbes known as the deltaproteobacteria. This was the first evidence that a substantial amount of acetate in the gut may be produced by a non-spirochete.
Because the genes from this deltaproteobacterium were found in the chunky particulate matter of the termite gut, the researchers thought that perhaps the newly identified microbe attaches to the surface of one of the chunks. To test this hypothesis, the researchers used a color-coded visualization method called hybridization chain reaction-fluorescent in situ hybridization, or HCR-FISH.
The technique—developed in the laboratory of Niles Pierce, professor of applied and computational mathematics and bioengineering at Caltech, and a coauthor on the PNAS study—allowed the researchers to simultaneously "paint" cells expressing both the active FDH gene and a gene identifying the deltoproteobacterium with different fluorescent colors simultaneously. "The microfluidics experiment suggested that the two colors should be expressed in the same location and in the same tiny cell," Leadbetter says. And, indeed, they were. "Through this approach, we were able to actually see where the new deltaproteobacterium resided. As it turns out, the cells live on the surface of a very particular hydrogen-producing protozoan."
This association between the two organisms makes sense based on what is known about the complex food web of the termite gut, Leadbetter says. "Here you have a large eukaryotic single cell—a protozoan—which is making hydrogen as it degrades wood, and you have these much smaller hydrogen-consuming deltaproteobacteria attached to its surface," he says. "So, this new acetogenic bacterium is snuggled up to its source of hydrogen just as close as it can get."
This intimate relationship, Leadbetter says, might never have been discovered relying on phylogenetic inference—the standard method for matching a function to a specific organism. "Using phylogenetic inference, we say, 'We know a lot about this hypothetical organism's relatives, so without ever seeing the organism, we're going to make guesses about who it is related to," he says. "But with the techniques in this study, we found that our initial prediction was wrong. Importantly, we have been able to determine the specific organism responsible and a location of the mystery organism, both of which appear to be extremely important in the consumption of hydrogen and turning it into a product the insect can use." These results not only identify a new source for acetogenesis in the termite gut—they also reveal the limitations of making predictions based exclusively on phylogenetic relationships.
Other Caltech coauthors on the paper titled "Localizing transcripts to single cells suggests an important role of uncultured deltaproteobacteria in the termite gut hydrogen economy," are graduate student Kaitlyn S. Lucey (environmental science and engineering), Elizabeth A. Ottesen (PhD '08, biology), graduate student Vikas Trivedi (bioengineering), and research scientist Harry M. T. Choi (PhD '10, bioengineering). This work was funded by the U.S. Department of Energy, the National Science Foundation, the National Institutes of Health, the Programmable Molecular Technology Center within the Beckman Institute at Caltech, a Donna and Benjamin M. Rosen Center Bioengineering scholarship, and the Center for Environmental Microbial Interactions at Caltech.
During the past century, programmable technologies evolved from spinning gears and vacuum tubes to transistors and microchips. Now, a group of Caltech researchers and their colleagues at the University of Washington, Harvard University, and UC San Francisco are exploring how biologically important molecules—like DNA, RNA, and proteins—could be the next generation of programmable devices.
Erik Winfree, professor of computer science, computation, and neural systems, and bioengineering, along with collaborators at Caltech and the University of Washington, began the Molecular Programming Project (MPP) in 2008, as part of an NSF Expeditions in Computing award to develop practices for programming biomolecules—much like a computer code—to perform designated functions. Over the past five years, the researchers have programmed DNA to carry out a number of tasks, from solving basic math and pattern-recognition problems to more mechanical tasks like programming RNA and DNA to selectively amplify fluorescent signals for biological microscopy. Through these initial experiments, the researchers have shown that it is possible to systematically encode specialized tasks within DNA molecules.
"Computer science gave us this idea that many tasks can actually be done with different types of devices," Winfree says. For example, a 19th-century cash register and a 21st-century computer can both be used to calculate sums, though they perform the same task very differently. At first glance, writing a computer program and programming a DNA molecule may seem like very different endeavors, but "each one provides a systematic way of implementing automated behaviors, and they are both based on similar principles of information technology," Winfree says.
Expanding the team to include five additional faculty who bring expertise in structural and dynamic DNA nanotechnology, synthetic biology, computer-aided design, programming languages, and compilers, Winfree and his colleagues recently received a second Expeditions in Computing award to take their work in molecular programming to the next level: from proof-of-principle demonstrations to putting the technology in the hands of users in biology, chemistry, physics, and materials science.
The researchers aim to use molecular programming to establish general-purpose, reliable, and easy-to-use methods for engineering complex nanoscale systems from biomolecules. In the hands of users, these methods could be used to create novel self-assembling electronic and optical devices, powerful nanoscale tools for the study of biology, and programmable molecular circuits for the diagnosis and treatment of disease. In one application, the researchers hope to program DNA molecules to carry out recognition and logical circuitry for exquisitely targeted drug delivery, thus reducing drug side effects and increasing efficacy.
Today, the largest synthetic molecular programs—human-designed sequences of the A, T, C, and G bases that make up DNA—contain on the order of 60,000 bases. "That's comparable to the amount of RAM memory in my first computer, a 1983 Apple II+," says Winfree. Designed systems in the future will only become more complex, a challenge that MPP researchers aim to tackle by approaching biological systems with something computer scientists call the abstraction hierarchy.
"In some sense computer science is the art of managing complexity, because you design things that have billions of components, but a single person simply cannot understand all the details and interactions," he says. "Abstraction is a way of hiding a component's details while making it easy to incorporate into higher-order components—which, themselves, can also be abstracted. For example, you don't need to know the details of a multiplication circuit in order to use it to make a circuit for factoring." In the molecular world, the task might be different—like transporting a molecular cargo to a designated location—but abstraction is still essential for combining simpler systems into larger ones to perform tasks of greater complexity.
"Over the next several decades, the MPP seeks to develop the principles and practice for a new engineering discipline that will enable the function of molecules to be programmed with the ease and rigor that computers are today, while achieving the sophistication, complexity, and robustness evident in the programmable DNA, RNA, and protein machinery of biology," says Niles Pierce, professor of applied and computational mathematics and bioengineering at Caltech and member of the MPP.
To integrate these fields, the MPP has brought together an interdisciplinary team of computer scientists, chemists, electrical engineers, physicists, roboticists, mathematicians, and bioengineers—all of whom have a strong research interest in the intersection of information, biology, and the molecular world. The team will explore the potential of molecular programming from many perspectives.
"Because of the diverse expertise that is required to work on these challenges, the participating students and faculty come from an unusual array of fields," Pierce says. "It's a lot of fun to be in a room with this group of people to see where the discussions lead."
The 2013 Expeditions award was granted for the proposal "Molecular Programming Architectures, Abstractions, Algorithms, and Applications." Winfree and Pierce are joined on the project by four other collaborators at Caltech: Jehoshua (Shuki) Bruck, Gordon and Betty Moore Professor of Computation and Neural Systems and Electrical Engineering; Richard Murray, Thomas E. and Doris Everhart Professor of Control and Dynamical Systems and Bioengineering; Lulu Qian, assistant professor of bioengineering; and Paul Rothemund, senior research associate in bioengineering, computing and mathematical sciences, and computation and neural systems. Other collaborators include Eric Klavins and Georg Seelig from the University of Washington, Peng Yin and William Shih from Harvard, and Shawn Douglas from UC San Francisco.
To expand its involvement in online learning, the California Institute of Technology will offer courses through the online education platform edX beginning this October.
The edX course platform is an online learning initiative launched in 2012 by founding partners Harvard University and the Massachusetts Institute of Technology (MIT). Caltech's rigorous online course offerings will join those of 28 other prestigious colleges and universities in the edX platform's "xConsortium."
This new partnership with edX comes one year after Caltech offered three courses through the online learning platform Coursera in fall 2012. The Institute will now offer courses through both platforms.
"Coursera and edX have some foundational differences which are of interest to the faculty," says Cassandra Horii, director of teaching and learning programs at Caltech. Both organizations offer their courses at no cost to participating students; edX, however, operates as a nonprofit and plans to partner with only a small number of institutions, whereas Coursera—a for-profit, self-described "social entrepreneurship company"—partners with many institutions and state university systems.
The two platforms also emphasize different learning strategies, says Horii. "Coursera has a strong organizational principle built around lectures, so a lot of the interactivity is tied right into the video," she says. Though edX still enables the use of video lectures, a student can customize when he or she would like to take quizzes and use learning resources. In addition, edX allows faculty to embed a variety of learning materials—like textbook chapters, discussions, diagrams, and tables—directly into the platform's layout.
In the future, data collected from both platforms could provide valuable information about how students best learn certain material, especially in the sciences. "Caltech occupies this advanced, really rigorous scientific education space, and in general our interest in these online courses is to maintain that rigor and quality," Horii says. "So, with these learning data, we have some potential contributions to make to the general understanding of learning in this niche that we occupy."
Even before joining edX and Coursera, Caltech had already become an example in the growing trend of Massive Open Online Courses (MOOCs). Yaser Abu-Mostafa, professor of electrical engineering and computer science, developed his own MOOC on machine learning, called "Learning from Data," and offered it on YouTube and iTunes U beginning in April 2012.
Since its debut, Abu-Mostafa's MOOC has reached more than 200,000 participants, and it received mention in the NMC Horizon Report: 2013 Higher Education Edition—the latest edition of an annual report highlighting important trends in higher education. The course will be offered again in fall 2013 on iTunes U, and is now also open for enrollment in edX.
Although Caltech is now actively exploring several outlets for online learning, the Institute's commitment to educational outreach is not a recent phenomenon. In the early 1960s, Caltech physicist Richard Feynman reorganized the Institute's introductory physics course, incorporating contemporary research topics and making the course more engaging for students. His lectures were recorded and eventually incorporated into a widely popular physics book, The Feynman Lectures on Physics, which has sold millions of copies in a dozen languages.
Continuing in the tradition set by Feynman, the MOOCs at Caltech seek to provide a high-quality learning environment that is rigorous but accessible. "No dumbing down of courses for popular consumption . . . no talking over people's heads either; at Caltech, we explain things well because we understand them well," adds Abu-Mostafa.
More information on Caltech's online learning opportunities is available on the Online Education website.
The lightweight skeletons of organisms such as sea sponges display a strength that far exceeds that of manmade products constructed from similar materials. Scientists have long suspected that the difference has to do with the hierarchical architecture of the biological materials—the way the silica-based skeletons are built up from different structural elements, some of which are measured on the scale of billionths of meters, or nanometers. Now engineers at the California Institute of Technology (Caltech) have mimicked such a structure by creating nanostructured, hollow ceramic scaffolds, and have found that the small building blocks, or unit cells, do indeed display remarkable strength and resistance to failure despite being more than 85 percent air.
"Inspired, in part, by hard biological materials and by earlier work by Toby Schaedler and a team from HRL Laboratories, Caltech, and UC Irvine on the fabrication of extremely lightweight microtrusses, we designed architectures with building blocks that are less than five microns long, meaning that they are not resolvable by the human eye," says Julia R. Greer, professor of materials science and mechanics at Caltech. "Constructing these architectures out of materials with nanometer dimensions has enabled us to decouple the materials' strength from their density and to fabricate so-called structural metamaterials which are very stiff yet extremely lightweight."
At the nanometer scale, solids have been shown to exhibit mechanical properties that differ substantially from those displayed by the same materials at larger scales. For example, Greer's group has shown previously that at the nanoscale, some metals are about 50 times stronger than usual, and some amorphous materials become ductile rather than brittle. "We are capitalizing on these size effects and using them to make real, three-dimensional structures," Greer says.
In an advance online publication of the journal Nature Materials, Greer and her students describe how the new structures were made and responded to applied forces.
The largest structure the team has fabricated thus far using the new method is a one-millimeter cube. Compression tests on the the entire structure indicate that not only the individual unit cells but also the complete architecture can be endowed with unusually high strength, depending on the material, which suggests that the general fabrication technique the researchers developed could be used to produce lightweight, mechanically robust small-scale components such as batteries, interfaces, catalysts, and implantable biomedical devices.
Greer says the work could fundamentally shift the way people think about the creation of materials. "With this approach, we can really start thinking about designing materials backward," she says. "I can start with a property and say that I want something that has this strength or this thermal conductivity, for example. Then I can design the optimal architecture with the optimal material at the relevant size and end up with the material I wanted."
The team first digitally designed a lattice structure featuring repeating octahedral unit cells—a design that mimics the type of periodic lattice structure seen in diatoms. Next, the researchers used a technique called two-photon lithography to turn that design into a three-dimensional polymer lattice. Then they uniformly coated that polymer lattice with thin layers of the ceramic material titanium nitride (TiN) and removed the polymer core, leaving a ceramic nanolattice. The lattice is constructed of hollow struts with walls no thicker than 75 nanometers.
"We are now able to design exactly the structure that we want to replicate and then process it in such a way that it's made out of almost any material class we'd like—for example, metals, ceramics, or semiconductors—at the right dimensions," Greer says.
In a second paper, scheduled for publication in the journal Advanced Engineering Materials, Greer's group demonstrates that similar nanostructured lattices could be made from gold rather than a ceramic. "Basically, once you've created the scaffold, you can use whatever technique will allow you to deposit a uniform layer of material on top of it," Greer says.
In the Nature Materials work, the team tested the individual octahedral cells of the final ceramic lattice and found that they had an unusually high tensile strength. Despite being repeatedly subjected to stress, the lattice cells did not break, whereas a much larger, solid piece of TiN would break at much lower stresses. Typical ceramics fail because of flaws—the imperfections, such as holes and voids, that they contain. "We believe the greater strength of these nanostructured materials comes from the fact that when samples become sufficiently small, their potential flaws also become very small, and the probability of finding a weak flaw within them becomes very low," Greer says. So although structural mechanics would predict that a cellular structure made of TiN would be weak because it has very thin walls, she says, "we can effectively trick this law by reducing the thickness or the size of the material and by tuning its microstructure, or atomic configurations."
Additional coauthors on the Nature Materials paper, "Fabrication and Deformation of Three-Dimensional Hollow Ceramic Nanostructures," are Dongchan Jang, who recently completed a postdoctoral fellowship in Greer's lab, Caltech graduate student Lucas Meza, and Frank Greer, formerly of the Jet Propulsion Laboratory (JPL). The work was supported by funding from the Dow-Resnick Innovation Fund at Caltech, DARPA's Materials with Controlled Microstructural Architecture program, and the Army Research Office through the Institute for Collaborative Biotechnologies at Caltech. Some of the work was carried out at JPL under a contract with NASA, and the Kavli Nanoscience Institute at Caltech provided support and infrastructure.
The lead author on the Advanced Engineering Materials paper, "Design and Fabrication of Hollow Rigid Nanolattices Via Two-Photon Lithography," is Caltech graduate student Lauren Montemayor. Meza is a coauthor. In addition to support from the Dow-Resnick Innovation Fund, this work received funding from an NSF Graduate Research Fellowship.
Trading in their textbooks for power tools this summer, a group of nine Caltech students and recent graduates have had a unique opportunity to apply their classroom knowledge to real-world challenges. Along with students in architectural design from the Southern California Institute of Architecture (SCI-Arc), the Caltech students have spent their summer building the Dynamic Augmented Living Environment (DALE), a joint SCI-Arc/Caltech entry in the 2013 Solar Decathlon competition. DALE marks Caltech's second collaboration with SCI-Arc, following their Compact Hyper-Insulated Prototype (CHIP), the partnership's first Solar Decathlon entry, in 2011.
Sponsored by the Department of Energy, the biennial Solar Decathlon competition challenges collegiate teams to "design, build, and operate solar-powered houses that are cost-effective, energy-efficient, and attractive." Contest rules state that each entry must be a net-zero home, meaning that its solar panels must produce at least as much energy as the home uses.
Construction on the SCI-Arc/Caltech collaboration began in March, when DALE's cement foundation was poured. In April, the home's steel frames were dropped in, allowing the students (guided by a few construction professionals) to begin nailing the lumber into place.
As of August, the home is starting to take shape; the bathroom has been framed out, the kitchen cabinets are set for installation, and soon the house will be sporting a vinyl exterior and a set of moving canopies that will hold its solar panels.
Although construction work only began a few months ago, the Caltech students began planning for DALE last fall in an engineering project course called Introduction to Multidisciplinary Systems Engineering, taught by Melany Hunt, Dotty and Dick Hayman Professor of Mechanical Engineering and a vice provost.
"I really like this project because it's very hands-on," says DALE team member Zeke Millikan (BS '13, mechanical engineering). "A lot of classes at Caltech are very theoretical, and I'm more of a hands-on type of person. It's really satisfying to actually build something and see it come together."
"Prior to this summer," says DALE team member Sheila Lo ('16), "I didn't really have a lot of experience in construction, so I spent a lot of time learning the terminology and how to use which tools in certain situations. As one of the youngest members of the team, it's been a great privilege to work with upperclassmen and recent graduates because they've taught me a lot about dedication to a project and what it means to apply the skills you learn at Caltech."
And this dedication will be important in the coming weeks, as there is still plenty of work to be done for the early-October competition. Unlike the five previous Solar Decathlons, which were held in Washington, D.C., this year's event will take place in nearby Irvine, California. "Having the competition just right down the road from us inspired the design," says DALE team member Ella Seal (BS '13, mechanical engineering).
To capitalize on Southern California's mild climate, DALE is made up of two moving modules that can glide apart on warm sunny days, creating an open indoor courtyard that can triple the home's available living space. During inclement weather—and for enhanced safety and privacy—DALE's modules can also move together, creating an enclosed home of about 600 square feet.
The home's untraditional moving design—conceived by SCI-Arc team members—is more than just eye-catching. "It also will actually save energy and money over the course of the year," says Seal. By varying the configurations of DALE's modules and shade canopies—the same ones that will hold DALE's solar panels—the Caltech students were able to optimize energy efficiency during different times of the day without sacrificing comfort. "During the summer, the air-conditioning energy consumption drops by at least half when you are able to open up the house and adjust the shading depending on the weather outside," says Millikan.
But a moving house also presents several engineering challenges, says Seal. Wires for electricity and pipes for plumbing had to be specially designed for their moving platform. Seal and Millikan were also tasked with creating a foolproof safety mechanism for DALE's movement systems. Applying their backgrounds in mechanical engineering, they created a system of laser beams, light curtains, and pressure sensors that acts "basically like a garage door sensor on steroids," says Millikan. "We think we've addressed pretty much every scenario where someone could get seriously hurt."
In addition to the movement systems, students from Caltech are responsible for designing the home's heating, ventilation, and air-conditioning system; hot water system; photovoltaic arrays; and other engineering aspects of the solar-powered home. As well as their technical contributions, the Caltech students will collaborate with their SCI-Arc teammates on publicity and fund-raising efforts and the compilation of a final written report.
"I appreciate the fact that it's not just engineering," says Seal. "I really like the fact that we have to write an engineering narrative, describing all of the really cool innovations that we've built into the house. It's not necessarily something that I would get to do if I took a different project class at Caltech."
This type of multidisciplinary and collaborative experience is important for Caltech students, notes Hunt. "Engineering students need experiences in which they design, create, build, and test," she says. "They also should have opportunities in which they work as part of a team. Most engineering projects require multiple perspectives with input coming from a range of individuals with different expertise and vision."
In addition to Millikan, Seal, and Lo, the DALE team includes current Caltech students Brynan Qui ('15), Do Hee Kim ('15), Sharon Wang ('16), as well as recent graduates Tony Wu (BS '13, mechanical engineering and business economics and management) and Christine Viveiros (BS '13, mechanical engineering), and project manager Andrew Gong (BS '12, chemical engineering [materials]). The SCI-Arc/Caltech project, along with other entries for this year's Solar Decathlon competition, will be open to the public October 3–6 and 10–13 at the Orange County Great Park in Irvine, California.