text:
|Publication number
|Publication type
|Application number
|Publication date
|Jun 17, 2003
|Filing date
|Dec 22, 1999
|Priority date
|Dec 22, 1999
|Fee status
|Also published as
|Publication number
|Glenn Lawson, Richard Terry
|Original Assignee
|C. R. Bard, Inc.
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (213), Non-Patent Citations (9), Referenced by (76), Classifications (20), Legal Events (4)
|External Links: USPTO, USPTO Assignment, Espacenet
The present invention relates to microbe resistant articles and compositions that are for internal or external use with humans or animals, and methods for making these articles and compositions.
Articles such as medical devices may be classified according to their method of use, i.e. as those used for total implants or those used as access devices. The medical access devices may be further classified as those that exit at a bodily orifice, such as a Foley catheter, and those that exit transcutaneously, such as venous catheters. Medical devices such as catheters, which come into contact with bodily fluids and organs, are often left in place for prolonged periods of time. Several problems are encountered from the use of indwelling catheters such as the introduction of bacteria during insertion or implantation or upon long term exposure of the catheter exit site to the environment. In addition, long-term catheter use often develops biofilm on the catheter surface reducing patient comfort and contributing to the possibility of infection.
Attempts have been made to prevent microbial infection related to catheter use by bonding an antibacterial agent to a catheter. For example, U.S. Pat. No. 5,476,509 describes a catheter having a polymeric coating that has an antibiotic agent covalently or ionically bound thereto. Similarly, U.S. Pat. No. 5,798,115 describes a catheter having a polymer coating that has an antibiotic covalently bonded to the polymer backbone. While these catheters may kill bacteria that are kept in contact with it for prolonged periods of time, the catheter is not effective at killing bacteria that are introduced into the body during insertion of the catheter since the antibiotic is attached to the catheter and the bacteria are able to diffuse away from the catheter. A different type of catheter is described in U.S. Pat. No. 5,019,096. In this patent, a catheter having a matrix-forming polymer in which an antimicrobial agent is impregnated, is described. Since the antibiotic is not covalently or ionically bound to the polymer, it is able to diffuse away from the catheter. While this catheter may show some effectiveness against bacteria introduced during insertion of the catheter, the long term antibacterial effectiveness is limited as the antibacterial agent diffuses out of the polymer coating in a relatively short period of time. In addition, short-term, incomplete killing of bacteria, such as that resulting from impregnated catheters, has been shown to encourage bacterial resistance.
It is known that hydrophilic coatings with low friction (coefficient of friction of 0.3 or less) are useful for a variety of medical devices such as catheters, catheter introducers, guide-wires and the like. When low friction devices are used, the devices, upon introduction into the body, slide easily within the arteries, veins, and other body orifices and passageways. In some cases, the material of the catheter or medical device is formed of a material having good antifriction properties such as poly(tetrafluoroethylene) or other plastics which tend to avoid abrasion with the body. However, in many cases the selection of material does not provide the anti-slip properties desired in conjunction with other desirable properties of the particular medical device. In other cases, the desired adherence of a lubricious coating to a particular substrate is not achieved. Thus, there exists a need for long-term, microbe resistant articles that do not enhance the likelihood of creating resistant infections and which have lubricious and durable surfaces.
This invention provides durable and lubricious compositions and articles that have a relatively potent short-term microbial resistance in addition to a sustained long-term microbial resistance. In addition, this invention provides methods for making microbially resistant compositions and articles wherein the compositions and articles have a relatively potent short-term microbial resistance and a sustained long-term microbial resistance and wherein the articles and compositions have a durable and lubricious surface.
In accordance with an embodiment of the invention, a composition is provided that is a multi-layer coating. The coating comprises a layer of metallic silver overlaid with a polymer, preferably a hydrogel, which contains an antimicrobial agent. In accordance with an additional embodiment of the invention, an article having a layer of metallic silver applied thereto which is overlaid with a hydrogel containing an antimicrobial agent is provided. Preferred articles for use according to the invention are medical articles. In particular, medical articles such as catheters are preferred. These articles have affixed to their surfaces a metallic silver layer which is covered by a hydrogel containing an antimicrobial agent. In accordance with a further embodiment of the invention, methods for producing the articles and the compositions of the invention are provided. The method comprises:
a) providing a layer of metallic silver
b) preparing a coating solution by dissolving a polymer, preferably a hydrogel, or the components to produce a polymer or hydrogel in one or more solvents
c) incorporating at least one antimicrobial agent into the coating solution; and
d) coating the metallic silver layer with the coating solution containing the antimicrobial agent.
Articles that embody the present invention generally can be any article that contacts patients or is used in health care. The articles may be for use either internally or externally, and include, for example, catheters, tubes, shunts, condoms, medical gloves, implants, sutures, grafts and the like. The articles can be made from a variety of natural or synthetic materials, such as, for example, latex, polystyrene, polyester, polyvinylchloride, polyurethane, ABS polymers, ceramics such as aluminum oxide, glass, polyamide, polimide, polycarbonate, synthetic rubber, stainless steel, silicone and polypropylene.
The metallic silver layer is formed by methods known in the art such as wet deposition, electroplating, sputter coating and vacuum deposition. A preferred method of forming the metallic silver layer is wet deposition as described in U.S. Pat. No. 5,395,651. The entire disclosure of U.S. Pat. No. 5,395,651 is incorporated herein by reference. Briefly, metallic silver is deposited upon the surface of an article using a multi-step wet deposition process. The surface is cleaned, and then activated in an aqueous solution containing tin. The silver is deposited from an aqueous solution of a silver-containing salt, a reduction agent that reduces the salt to form the metallic silver, and a deposition control agent that prevents the silver from nucleating throughout the solution. After the article is coated, the coating is stabilized as described in U.S. Pat. No. 5,395,651. The metallic silver layer can be between about 2 angstroms and about 10 microns. A preferred thickness is between about 2 angstroms and about 2,000 angstroms. Alternatively, the amount of silver deposited is determined by weight per unit area. The amount of silver deposited can be from about 0.1 μg/cm2 to about 100 μg/cm2. A preferred about of silver deposited per unit area is from about 0.5 μg/cm2 to about 20 μg/cm2.
Nearly any hydrophilic polymer can be used according to this invention. For example, a polyurethane coating which takes up about 10% by weight of water or less can be used. Polymer coatings which are water soluble can also be used. For example, polyvinylpyrrolidone (PVP), which dissolves off when wet, can be used. However, polymer coatings known as hydrogels are preferred. Hydrogels for use according to the invention are those polymers known in the art that exhibit about 25% by weight to about 500% by weight water uptake. Preferably, the hydrogels for use according to this invention exhibit about 50% by weight to about 200% by weight water uptake, and, more preferably, from about 75% by weight to about 150% by weight water uptake. The hydrogels may be derived from water-soluble polymers including, but not limited to, poly(ethylene oxide), poly(ethylene glycol), poly(vinyl alcohol), polyvinyl-pyrrolidone, poly(ethyloxazoline), polyamino acids, pseudopolyamino acids, as well as mixtures of these with each other or other water-soluble polymers. These water-soluble polymers are complexed with or covalently bound to a second polymer, for example, a polyurethane, a polyurea, a polyurethaneurea, as well as mixtures of these with each other or with other polymers. The second polymer can be added as a preformed polymer or it can result from the polymerization of monomers which are polymerized in the presence of the water-soluble polymer. The polymerization reaction can take place before or after coating the substrate. The second polymer may or may not be cross-linked. If the second polymer is cross-linked, a preferred amount of cross-linking is between about 50% to about 90% or greater. A preferred polymer for coating is a polyether polyurethaneurea block copolymer which is not cross-linked. For example, the polyether polyurethaneurea block copolymer known as D6/40 obtained from Tyndale Plains-Hunter, Ltd. is a preferred polymer.
Antimicrobial agents useful according to this invention include the biquanides, especially chlorhexidine, polymyxins, tetracyclines, aminoglycosides, rifampicin, bacitracin, neomycin, chloramphenicol, miconazole, quinolones, penicillins, nonoxynol 9, fusidic acid, cephalosporins, mupirocin, metronidazole, cecropins, protegrins, bacteriocins, defensins, nitrofurazone, mafenide, acyclovir (U.S. Pat. No. 5,744,151), vancomycins, clindamycins, lincomycins, sufonamides (U.S. Pat. No. 5,869,127), norfloxacin, pefloxacin, nalidixic acid, oxolinic acid (quinalone), enoxacin, ciprofloxacin, and fusidic acid (U.S. Pat. No. 5,019,096) and combinations thereof. A preferred antimicrobial agent is chlorhexidine, as it exhibits a synergistic effect with silver.
The antimicrobial agent is incorporated in the compositions of this invention in an amount that is effective at inducing microbial stasis or killing to produce microbial resistant compositions. Methods for determining microbial stasis or killing are know in the art and include, for example, measuring the minimum inhibitory concentration (MIC) of coated catheter extracts, zone of inhibition (ZOI) testing, and bacterial adherence testing, using known clinical pathogens for all tests.
A coating solution is prepared by dissolving a polymer or polymer components in a solvent. The solvent may be any organic solvent or combination of solvents that preferably includes a polar organic solvent. In addition, water may be used as a solvent either alone or as a mixture with organic solvents. An antimicrobial agent, preferably dissolved in a solvent, is then added to make the antimicrobial coating solution. For example, a hydrogel forming polymer such as a polyether polyurethaneurea is dissolved in a mixture of tetrahydrofuran (THF) and an alcohol to form a 3% weight/polymer solution. The ratio of THF to alcohol typically ranges from about 50% to about 100% THF. Chlorhexidine is dissolved in the same alcohol used to make the coating solution or in dimethylacetamide to form about a 5% solution by weight. The chlorhexidine solution is then added to the coating solution in an amount that produces a coating that contains about 1% to about 10%, preferably about 1% to about 5%, chlorhexidine based on the dry weight of the coating. The coating solution is then applied to a silver coated article by dip or spray coating techniques.
The superior and unexpected results obtained from the compositions, articles and methods of the present invention result from the dual modes of action resulting from two distinct antimicrobial layers. For example, when a catheter is inserted into a patient, there is a likelihood that microorganisms will be introduced along with the catheter. This sudden introduction of a relatively large number of microorganisms is suppressed by the chlorhexidine diffusing from the coating of the catheter. Once indwelling, the catheter continues to release chlorhexidine and prevent infection in the surrounding tissue. As the chlorhexidine becomes depleted, the surface of the catheter continues to be antimicrobial due to the metallic silver coating. Silver ions released from the metallic silver layer prevent microbial migration along the shaft of the catheter into the body. The continued presence of silver on the catheter surface and the slow release of silver ions not only prevents the attachment of bacteria, it also inhibits the development of biofilm. In fact, silver catheters with a polymer coating have been reported to delay the onset of urinary tract infections, in spite of their limited ability to kill bacteria on contact, as evidenced by the lack of zones in the ZOI test described below. In addition, the presence of silver ions weakens bacteria by a different mechanism from chlorhexidine, reducing the potential for the development of a resistant infection. Thus, the coatings of the present invention offer resistance to bacterial migration and growth resulting from the silver coating plus they offer additional resistance due to a rapid release of an antimicrobial agent which kills bacteria introduced upon insertion of the catheter.
The following examples are presented to illustrate the present invention, but are in no way to be construed as limitations on the scope of the invention. It will be recognized by those skilled in the art that numerous changes and substitutions may be made without departing from the spirit and preview of the invention.
A silver layer was deposited upon the inside and the outside of a catheter made of latex (natural rubber) according to the following procedure. The latex catheter was cleaned by dipping it in a cleaning solution containing 1-5 percent of sodium hypochlorite, at ambient temperature for 2 minutes, followed by rinsing in demineralized water. The catheter was then dipped into an activating solution of 0.05 grams per liter of stannous chloride at ambient temperature for 10 minutes, followed by rinsing in demineralized water. Silver was deposited on the catheter by dipping it into a bath containing 0.01 grams per liter of silver nitrate, 0.10-0.12 grams per liter sodium nitrate, and sufficient ammonia to achieve a pH of from about 8.5 to about 9.5. Lastly, the silver layer was stabilized by dipping it in a 0.1% solution of platinum chloride in hydrochloric acid at a pH of about 4.1 for a time of 1 minute at ambient temperature.
A 3% polymer coating solution containing 3% (dry weight) of chlorhexidine was prepared by first dissolving 10.3 g of a polyether polyurethane-urea block copolymer (Tyndale Plains-Hunter) in 334.0 g tetrahydrofuran (THF). Next, a 5% solution of chlorhexidine was prepared by dissolving 0.31 g chlorhexidine in dimethylacetamide. The two solutions were then combined with stirring to form the final coating solution. Latex Foley catheters (16 Fr) which were previously silver coated as described above were then dipped into the polymer/chlorhexidine solution and removed at a constant rate to provide an even outer coating of lubricious, hydrophilic polymer containing chlorhexidine.
Upon contact with aqueous fluids, catheters coated as described above absorb moisture and become lubricious, or slippery, to the touch. The degree of lubricity of the coating was measured by a test of Coefficient of Friction (COF). In this test, a pair of catheters was positioned in a trough of water and a 400 g stainless steel sled wrapped with a cellulose membrane was pulled down the shafts of the pair of catheters. The force required to pull the sled was averaged over a length of the catheter, and this force was divided by the weight of the sled to give a unitless value of COF.
The COF for the catheters produced according to the methods described above averaged 0.06. A typical range of COF for the preferred hydrophilic coating of the invention is 0.02 to 0.15. The most preferred range of COF for coatings of the invention is 0.02 to 0.08.
The durability of coatings produced according to the methods described above and other hydrophilic coatings of the invention were determined in two ways. First, the catheters were tested for COF over a period of 21 days. In this test, catheters were incubated in deionized water at 37� C., and COF was measured after one hour, 1, 7, 14 and 21 days. The durability of the coating was then determined by the change in COF over the 21 day period. Coatings that change very little or increase their lubricity from the first to the 21st day of testing are considered durable. A second test of durability was to hold the hydrated, coated catheter in a wet hand and rub the thumb back and forth ten times on the coated shaft, traversing a distance of about one inch. The coating is considered very durable if it maintains its lubricity after ten rubs. A low durability coating rubs off in this test.
Antimicrobial activity was determined by two methods, zone of inhibition (ZOI) and bacterial adherence (BA). For ZOI, one quarter inch segments of catheter were incubated in an agar culture of a test organism. After 24 hours, a measurement was made of the proximity of the bacteria to the surface of the catheter segment. If a sample released an antimicrobial agent, a ring containing no bacterial growth was evident around the catheter segment and the distance in millimeters from the catheter surface was defined as the zone of inhibition. In the ZOI test, catheters produced according to the methods above exhibited zones ranging from 1 to 5 mm for ten different test organisms. See Table 1. Control samples of catheters coated with silver and lubricious polymer but no chlorhexidine showed no zones of inhibition when tested against the ten test organisms.
Antimicrobial activity was also demonstrated for catheters coated according to the methods described above by bacterial adherence testing. In this test, catheter segments were incubated for 18 hours in a solution containing radiolabeled bacteria. The catheter segments were then rinsed and the number of organisms that adhered to the catheter segment was determined by scintillation counting. Coatings produced according to the present invention showed a significant decrease in the number of bacteria that adhered to the coating surface when compared to coatings simply having a lubricious coating over a silver layer for each of the ten clinically relevant bacteria shown in Table 1.
Zone of inhibition testing
on a Bardex IC Foley catheter coated according to the
invention such that the coating comprised 2.9% chlorhexidine.
Sample 1
Sample 2
Candida albicans (GSU-30)
3 mm
3 mm
Citrobacter diversus (koseri)
4 mm
4 mm
Enterobacter cloacae
2 mm
2 mm
Enterococcus faecalis (urine)
3.5 mm
4 mm
Escherichia coli (UTI)
4.5 mm
4.5 mm
Klebsiella pneumoniae (UTI)
2 mm
1.5 mm
Proteus mirabilis (UTI)
<1 mm
<1 mm
Pseudomanas aeruginosa (GSU-3)
1.5 mm
1 mm
Staphylococcus saprophyticus
4 mm
5 mm
Enterococcus faecium (UTI)
4.5 mm
4 mm
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|Oct 14, 1988
|May 28, 1991
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|Mar 31, 1989
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|Jan 22, 1990
|Sep 17, 1991
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|Apr 24, 1990
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|Dec 31, 2009
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|Aug 5, 2010
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|Mar 9, 2009
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|Jul 7, 2010
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|Jan 11, 2007
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|Feb 22, 2007
|Thomas A Fuller
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|U.S. Classification
|424/618, 604/265, 427/2.3, 424/78.17, 427/2.1, 424/617, 424/78.08, 424/422, 424/600
|International Classification
|Cooperative Classification
|European Classification
|Feb 12, 2002
Owner name: C.R. BARD, INC., NEW JERSEY
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:LAWSON, KENNETH GLENN;TERRY, RICHARD N.;REEL/FRAME:012897/0550
Effective date: 20020211
|Nov 27, 2006
|Fee payment
Year of fee payment: 4
|Nov 18, 2010
|Fee payment
Year of fee payment: 8
|Nov 19, 2014
|Fee payment
Year of fee payment: 12


text:
Book your room at Hampton Inn Atlanta Airport
Get an overview of this hotelCollege Park, GA hotel by international airport
Close to airport
This hotel is in College Park, Georgia, two miles from Hartsfield-Jackson Atlanta International Airport and 2.2 miles from the Georgia International Convention Center.
Airport shuttle
Hampton Inn Atlanta Airport offers a complimentary buffet breakfast and complimentary airport shuttle. This College Park hotel includes a meeting room.
High-speed Internet
Hampton Inn Atlanta Airport 127 guestrooms provide cable TV, complimentary high-speed Internet access, coffee/tea makers, and bathrooms with hair dryers and telephones.Would you like to give us feedback? Share it! Opens in a new window
Hampton Inn Atlanta Airport1888 Sullivan Rd College Park GA 30337
Hotel Amenities
Hotel Amenities
Hampton Inn Atlanta Airport provides complimentary breakfast each morning. On Monday through Wednesday evenings, the hotel hosts a complimentary evening social. Airport transportation is complimentary, and the hotel provides a complimentary shuttle that takes guest within three miles of the property.
This College Park hotel has an outdoor pool and offers fitness equipment. A meeting room is on site; high-speed Internet access is complimentary. The hotel offers dry cleaning and features an accessible path of travel.
- Free airport transportation
- Total number of rooms - 127
- Number of floors - 4
- ATM/banking
- Free breakfast
- Business center
- Dry cleaning/laundry service
- Elevator/lift
- Express check-in
- Express check-out
- Fitness facilities
- Free WiFi
- One meeting room
- Free self parking
- Long-term parking (surcharge)
- Number of buildings/towers - 1
- Television in common areas
- Free wired high-speed Internet
- Free area shuttle
- Free reception
- Smoke-free property
- Outdoor pool
Family Friendly Amenities
- Outdoor pool
- Free Wi-Fi
- Area shuttle (complimentary)
Available in all rooms: Free WiFi , Free wired high-speed Internet
Available in some public areas: Free WiFi , Free wired high-speed Internet
Long-term parking (surcharge), Free self parking
Room Amenities
- Air conditioning
- Blackout drapes/curtains
- Cable TV service
- In-room climate control (air conditioning)
- Coffee/tea maker
- Free weekday newspaper
- Free toiletries
- Cribs/infant beds available
- Desk
- Free local calls
- Hair dryer
- Daily housekeeping
- Iron/ironing board
- Free WiFi
- Premium bedding
- Shower/tub combination
- Phone
- Room service (limited hours)
- Free wired high-speed Internet
Where to Eat
Hampton Inn Atlanta Airport provides complimentary buffet breakfast, which includes a waffle bar. On weekdays, the hotel also offers bagged to-go breakfast. On Monday through Wednesday evenings, the hotel hosts a complimentary manager's reception.
Nearby Things to Do
Hampton Inn Atlanta Airport has an outdoor pool and fitness equipment.
The recreational activities listed below are available either on site or nearby; fees may apply.
To make requests for specific accessibility needs, complete the "Special or Accessibility Requests" section of "Trip Preferences" when you book your hotel.
Hotel Policies
Check-in time starts at 3 PM
Special check-in instructions:
Check-out time is noon
Payment types
- Pets not allowed
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
Hotel Name
- Atlanta Airport Hampton Inn
- Hampton Inn Atlanta Airport
- Hampton Inn Hotel Atlanta Airport
- Hampton Inn Atlanta Airport Hotel
- Hampton Inn Atlanta Airport Hotel College Park
- Hampton Inn Atlanta Airport College Park

subset: commoncrawl


text:
Inside Petra: World Heritage Site and a check off the bucket list...
Petra is a historic red-rock city carved directly into soaring sandstone cliffs in the Ma'an Governorate of Jordan.
Petra (meaning "stone" in Greek) was inhabited by the Nabateans, an ancient, nomadic Arabic tribe who designated Petra as their capital city circa 6th century B.C. Travelers walk through al-Siq السيق also known as "the sic," to reach the official entrance to Petra - and the long stroll through the narrow gorges is the only way to access the city. The mountains tower around you with swirls of every shade of red until you see the resplendent first view of the Treasury building appear in the distance.
Around the city you'll find numerous ruins of tombs and temples. If you climb the hundreds of steps to the top of the archeological site you'll find an impressively in tact Monastery, worth-the-climb views, Bedouin style shops and places to sit and drink tea along the way.
Petra is a necessary stop for travelers, explorers, historians...any souls who marvel at the astounding work and capacity of mankind.


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Reviews for this FedEx Office Print & Ship Center7/22/2016Justin was very helpful and knowledgeable on all the products that I was looking for to make my project. He was also very pleasant and nice. Read more7/21/2016I needed to find something and he found it and made recommendations on what else I needed. Read more7/8/2016Center 1853 Location bufki is great! Justin, the manager, is always extremely helpful. He has helped up each time and makes us feel welcomed… Read more6/22/2016The worker who helped/assisted me with my copies was Mitch at center number 1853 and Location code : BUFKI. Mitch greeted my husband and I… Read more6/13/2016Mitch was great in assisting us completing our wedding invites. He was extremely friendly and very knowledgeable when it came to the… Read more6/8/2016Justin was extremely helpful. He saved me hours of time. He was very knowledgeable about the machines and was able to adjust them to fit my… Read more6/8/2016After leaving another fed ex close by, who was unable to assist me, I was sent to Justin. I needed copies of blue prints for a project our… Read more5/18/2016Justin really did a great job with my project. I was extremely satisfied with the final product. Pictures were very clear, better than I had… Read more5/3/2016Mike, at the Sheridan near Delaware office, was very kind when I came in to pick up my order. He had everything set and I had payed ans was… Read more4/19/2016I received excellent service from Justin S. He was knowledgeable, professional, and courteous. He explained that my sign could be mounted on… Read more4/15/2016I was extremely satisfied with the finished product. So I placed an order for 5 additional board mounted photos. Justin did an outstanding… Read more3/26/2016He was friendly and greeted me. He also showed me paper samples immediately after I asked to see them. My team members name was Mitch. He… Read more3/24/2016Mitchell K. was very prompt and freindly. Read more3/21/2016I frequently have work done at this location, you are located right near my place of business and I receive amazing service each time. I am… Read more3/3/2016Justin was extremely helpful. It was a pleasure doing business at this location. I did not get a sample copy of my order because I chose not… Read more2/16/2016We have gone to this location many times. We always come back due to the amazing, and friendly service. Justin, the manager at this location… Read more2/16/2016Justin is always a huge help at this location! I always use Fedex office for my printing needs due to convince and service quality. Will… Read more1/30/2016I don't recall the name of the team member but he was very helpful and remained so while he was assisting two other customers at the same… Read more1/27/2016excellent customer service. Read more1/20/2016The team members name is Mitch. I use this fed ex location often and have had the pleasure of positive experiences with Mitch and other… Read more
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Rep. Pascrell: Republicans won't hold us hostage any longer
Democratic lawmaker on 'fiscal cliff' talks
Democratic lawmaker on 'fiscal cliff' talks
Juan: Well I'll give him some credit, the polls are tightening. I attribute this to him not committing massive self inflicted wounds every other day and alienating his own party. Probably more moderate republicans are will to trust him. I don't know how he expands his constituency with his current positions on the issues and the electoral map is a huge advantage for democrats. Hillary needs to get out of the Hamptons and back in the public eye. All you see or hear anymore is Trump.


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Live Commentary
Mohammedan hold on to a 1-0 win but could have got many more in a match they dominated while Khalid Jamil will certainly be disappointed with how his team played.
90' + 2'CHANCE! Tolgay with a cross from the right and Dane Pereira's clearance almost found it as an own goal.
90'CHANCE! Penn dribbles in but with no black shirts in sight, he tries to smash it in the near post, but goes high.
87'CHANCE! Wrong decision by Ishfaq who wants to do it all on his own when he could have easily picked out Gurung who was in acres of space.
82'CHANCE! Two great saves by Ashok Singh to keep his team's lead. Cardozo goes down the left and his shot is well kept out by the goalie and the ensuing rebound by Anwar Ali is smashed over the bar.
80'Brandon Cardozo with a run down the right after the corner falls back but is well marshalled by Sandeep Sangha
78'SubstitutionSandjar Ahmadi Rohit Mirza
77'Yellow Card Rakesh Masih
72'SubstitutionHashmatullah Barikzai Branco Cardozo
71'CHANCE! This time some good work down the right by Colin Abranches whose cross just evades Penn Orji who throws himself on the floow to reach it.
70'CHANCE! Gurung with a great run down the right but he takes it too wide before pulling it back for Penn Orji who leaves it for Anthony Soren who shows some lovely feet only for the chance to be wasted as it is well blocked.
69'SubstitutionAhmad Hatifie Jayesh Rane
68'SubstitutionAjay Singh Ishfaq Ahmed
68'SubstitutionJosimar Tolgay Ozbey
68'Penn tries to break again but he cannot thread his pass to Tolgay who looked to make a run down the right.
64'CHANCE! Penn's freekick is only parried by Nidhin Lal and Josimar almost gets at the end of it but his overhead kick only finds Penn whose shot is wide.
63'BLATANT FOUL! Josimar clean through after Penn had played him through. But brought down outside the box by Amiri who incredibly escapes a booking.
61'Anthony Soren tries to play an one two with Josimar but the burly Brazilian is well heralded by Anwar Ali.
58'Mohammedan with a chance to break! Josimar and Penn break down the left while Gurung is free down the right. But Josimar's return ball to Penn who has strode forward is too weak allowing Dane Pereira to cover.
57'CHANCE! Ajay Singh runs down the left and puts in a lovely cross between the two centre backs. Josimar tries to take it on his right foot before shooting but gives enough time for Anwar Ali to block.
55'CHANCE! Amiri with a snapshot from just outside the box after a Mumbai FC corner but well held by Ashok Singh.
53'CHANCE! Slack play from the Mumbai defense as Colin strides forward with the ball leaving the ball to Gurung down the left whose inch perfect cross finds Josimar whose header is brilliantly blocked by Anwar Ali.
50'Mohammedan with the better play but still not being able to kill the game.
47'CHANCE! Ahmadi with a header as Sandeep Singha loses him but it comes off the crossbar
And we are in half time in what was a pretty drab match. Although Mohammedan Sporting did manufacture some chances Mumbai FC looked simply lacking any sort of positive intent with the two Afghanistani front men looking ineffective.
44'Mumbai FC with a chance as Ahmadi does ever so well down the right to play it back to Hshmatullah who takes too long to line up his shot allowing Sobrosa to get a block in.
42'CHANCE! Colin Abranches with a great through ball for Josimar. Josimar clean through with only Amiri to beat but the goal keeper does well.
40'SubstitutionGagandeep Singh Phoolchand Hembram
38'Mohammedan still trying to lump the ball forward to Josimar but well ushered out by Anwar Ali.
34'Penalty Goal Josimar
GOAL! Josimar's spot kick though not well struck rolls under Nidhin Lal's outstretched hands.
33'Brilliant play from Mohammedan which earns them a PENALTY. Penn Orji plays a brilliant ball which finds Ajay Singh unmarked down the right whose shot hits the hand of Ritesh Perambra.
32'CHANCE! Colin Abranches with a snapshot from outside the box. Again tipped well by Nidhin Lal
31'Gagandeep tries a long ball from beyond the half line which finds Josimar whose header is saved well by Nidhin Lal
30'Mumbai FC's Afghanistani midfielder, Hatife tries a shot from afar but loops over
28'Anthony Soren tries a long range effort and boy oh boy it wasn't that wide too as it just sails to the right of Nidhin Lal.
23'Nicholas Rodrigues with yet another chance to bang the ball in from the freekick but well cleared by Mohammedan. The Black and Whites want to break but fail.
21'Mohammedan with the better play but both teams lacking the incision upfront.
20'CHANCE! Lovely play between Penn Orji and Colin Abranches who plays Ajay Singh through but he cannot reach on time as Nidin Lal somehow collects.
16'Collin Abranches saves Sandeep Sangha's blushes as he fails to control the long ball with Ahmadi almost through
13'Yellow Card Gagandeep Singh
13'Sandjar Ahmadi wants to test Ashok Singh from afar and not a bad effort as it just goes wide of his left post.
8'CHANCE! Gurung with a fantastic corner which finds Luciano unmarked at the far post but his header is straight to the goalkeeper who pulls off a smart save. The goalkeeper probably did not know much about it. Josimar cannot do much on the rebound as he hits it straight to Nidhin Lal.
7'Tidy freekick by Penn. The ball falls to Gurung outside the box but his weak shot is straight to the goalkeeper.
6'Now Mohammedan win a freekick from the right side of the penalty box as Colin Abranches is brought down.
5'Rodrigues with another free kick this time from the right side. But well headed out by the Mohammedan defense.
4'Slightly niggly around here as we have had a clutch of fouls
2'Nicolas Rodrigues with a free kick. That was almost going to be an own goal as a Mohammedan head almost put it into his own net but good save by Ashok Singh.
1'And we have kicked off in earnest. Collin Abranches aims a long ball towards Josimar but just evades the big Brazilian.
Surprisingly there is a decent turnout especially with Sachin Tendulkar playing his penultimate test at Eden Gardens simultaneously.
This is Kaustav Bera and I will be bringing you the action LIVE from Salt Lake Stadium.
Hello and Welcome to GOAL's LIVE coverage of the I-League clash between Mohammedan Sporting and Mumbai FC


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Showing 1-12 of 12 items found in Sports & Gaming
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Lincoln Speedway's quarter-mile track is located on the Logan County Fairgrounds in Lincoln. The dirt track opened in 2004. Races are scheduled from April through September.
This authentic dirt racetrack offers minor races from May to mid-September.
Sudden Impact has been a locally owned and operated paintball field since 1992. The motto since day one has been "Safety First". The 100 acres has 3 wooded fields, and 3 concept fields - hyperball, airball, and a 2010 Race 2 style field is a perfect place for any one to try paintballing!
This motor raceway located in Lincoln allows a field of 18 different cars, including big buggies, electric bugs, trucks, sprinters and modifieds.
Golf with your family on this great course. 18 holes of fun are in store for your family when you visit North Greens. You will be challenged at your game and have a great time teeing off!
Come and bowl with your family or a group of friends at Lincoln's bowling center.
Tazewell County's newest sports complex. 75,900 square feet this versatile facility is unlike any other in all of Illinois. There is literally something for everyone as the Avanti's Dome plays host to soccer, softball and football leagues and tournaments, as well as trade shows, meetings and conventions.
18-Hole, 6414 yard, par 72 public golf course. Front nine opened July 4, 1993; Back nine added July 4, 2002. Bentgrass greens, bluegrass/rye mix fairways, tees, and rough. Banquet facility to accommodate up to 110 guests and clubhouse seating for up to 200. Full service pro shop fully stocked with golf clubs, balls, equipment, clothing, towels, hats, and shoes. Practice facilities include drivingvrange with three target greens, chipping and putting green, practice bunker.
Four Willows features a nine-hole, par 35 course.
CITY:Mason City
Lick Creek Golf Course is located at 2210 N. Parkway Drive in Pekin, Illinois. During it's recent renovation, all of the tees and fairways were converted to bentgrass and the greens were re-planted with a newer generation to allow for faster, truer ball roll on greens. All of the bunkers were rebuilt and the golf car paths were re-paved with new asphalt. Lick Creek offers a driving range, pro shop and concession area for all golfers needs. We have expanded our dates for weekdays and weekends for these events no matter how big or small your event may be. Considered one of the best golf course in Central Illinois, you will be impressed at our low cost to play. Daily fees and season pass fees listed on this website. Lick Creek was rated 4 stars by Golf Digest in 2007.
A nice course open year round with some hills to add that extra challenge! This is a course you can walk and enjoy playing anytime. Parkview is an 18 hole course totaling 6002 yards and open seven days a week with twilight fees available. Located just east of Parkway Drive. Buy your season pass or a coupon book and play both Parkview and Lick Creek courses. We also invite you to shop for your golfing needs in our club houses.
The Rt. 66 Arcade Museum is chock full of vintage pinball and video games from the 1930s-1970s - most of which can be played. It's the perfect place to misspend your youth all over again, one quarter at a time!
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