text:
#DairyBreakfastClub Linky Party & $250 Giveaway! Share your recipes
Are you ready?!!!!!!!!
Today is the day. The day we celebrate breakfast ! It's time to grab those aprons and share your favorite breakfast recipe that includes dairy. Link up at the end of this post (or share in the comments) and you will be entered to win a $250 Amazon gift code. (details below)
Why are we celebrating a dairy breakfast? Because the California Milk Advisory Board and I have teamed up to talk about the importance of a nutritious breakfast, that includes dairy. We want to remind you that, not only is the calcium in dairy important for growing strong bones, but it's also packed full of protein.
Have you seen their commercials? They were the inspiration for our partnership. They show how California dairy can be a part of everyday family life, like breakfast. Go check them out here – my favorite is the California cow singing in the shower while the family enjoys breakfast downstairs! lol
Last week I flew to Orlando to visit the Daily Buzz TV and talk about this very issue and share the recipe for my Southwest Baked Egg Cups with California cottage cheese and other varieties of California cheese. Check it out!
Nutritious Breakfast includes Dairy
Adding dairy to your breakfast, can help you from becoming hungry before your next meal. Kids who eat a nutritious breakfast may learn better and even do better in school, because they are less likely to have hunger pains, such as -being tired, getting headaches or even become cranky.
The first step to making sure your kids eat a nutritious breakfast, is to set a good example, by making healthy food choices . Make sure YOU are eating breakfast. Keep simple grab-and -go foods on hand such as California cottage cheese and yogurt cups, string cheeses and fruit. You can even make a breakfast casserole, such has Southwest Baked Egg Cups or Creme Brulee Baked Oatmeal the night before. Store in the fridge, and simply heat in the microwave the next morning.
Ease Morning Routines
Mornings can be a crazy time in any household, whether you have little ones to help get out the door, or not. Ease the morning scramble by getting everything ready the night before, such as: back packs, signed permission slips, lunches, even car keys and cell phones. Have them all gathered and in a designated spot, either by the front door or on a table. That way you avoid that morning panic when you can't find a jacket or homework paper that is due.
UPDATE: Giveaway has ended. Thanks to everyone who participated!
Congrats to the winner! Comment #45
Since breakfast is an important part of starting your day off right, we have asked TidyMom readers to share their favorite breakfast recipes that include dairy, for a chance to win a $250 Amazon gift code!!
1. Write and post a breakfast recipe that includes dairy, on your blog*. (you can link an old post…just PLEASE be sure to link back AND follow #2 below) *if you don't have a blog, see #4
2. Include "Come join #DairyBreakfastClub recipe party at TidyMom along with The California Milk Advisory Board and RealCaliforniaMilk.com " in your blog post. (you MUST include this in you blog post to be eligible for prize)
3. Starting today, March 18th thru March 25th add your link to your breakfast recipe post to the widget (below) and LEAVE A COMMENT on this POST letting me know you linked up. (you can add up to 2 recipes)
4. Don't have a blog? no problem…..leave your breakfast recipe, that includes dairy (it must be a recipe, not just something like fruit + yogurt) in the comments on this post during The Dairy Breakfast Club recipe party (March 18-25 , 2012) **recipes sent via email will not count as an entry
5. We'd love your help spreading the word about the Dairy Breakfast Club through social media outlets such as Facebook, Twitter , Pinterest and Instagram using the hashtag #DairyBreakfastClub ( Share a link with info about this party on any of your social media outlets. Return to this post and leave a comment letting me know where it was shared. Each place you share it and comment will grant you an additional entry. )
- Sample Tweet: Join @TidyMom & @RealCalifMilk for the #DairyBreakfastClub party Share #recipes & #WIN $250 at http://bit.ly/dairyrecipes 3/18-25
- Instagram photos of your breakfast using the hashtag #DairyBreakfastClub
6. Button for your sidebar or post – if you would like a button for your sidebar or post, copy the code here
***BE SURE TO LEAVE A COMMENT FOR EACH RECIPE YOU LINK UP (up to 2) and a separate comment for each social media share – your comments are your entries!
if you have any questions, feel free to email me
Official Rules: No purchase necessary. Must be over 18. Giveaway will end on March 25, 2013 at 11:59 pm CST. One winner with a valid entry will be selected at random using random.org. Winner will be notified by email and will have 48 hours to claim their prize or another winner will be selected. TidyMom is not responsible for lost or undelivered emails. Prize: $250 Amazon gift code.
Disclaimer: I'm excited to have a working partnership with the California Milk Advisory Board to talk about the importance of eating a nutritious breakfast complete with dairy and how to ease morning routines for moms. All opinions and views are all my own.
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143 comments
I don't have a blog to link to but I love the baked egg breakfast cup recipe. I've been trying to think of more protein packed breakfasts for our kids. These are perfect because I am NOT a morning person and I can make them ahead of time! Thank you so much for the great recipe.
Our favorite recipe breakfast recipe that includes dairy is a breakfast smoothie. Since it is a smoothie, it is also great to pair with a bagel or something else to get even more out of our breakfast meal.
Breakfast Smoothie:
1 container plain yogurt
1 banana
1/3 c peanut butter
1/2 c milk
1 c crushed ice
(optional) chocolate syrup or chocolate carnation drink mix
Throw everything in the blender and blend until everything is mixed!
I shared two links!
I tweeted @smiliemommy to get an entry into this awesome contest! 🙂
Blueberry Cream Cheese Bread
½ cups Butter
½ cups Sugar
¼ teaspoons Salt
1 teaspoon Vanilla Extract
2 whole Egg Yolks
1-½ cup All-pupose Flour
1 teaspoon Baking Powder
⅓ cups Milk
1-½ cup Blueberries
1 Tablespoon All-purpose Flour
2 whole Egg Whites
¼ cups White Sugar
8 ounces Cream Cheese
½ cups Sugar
1 Tablespoon Flour
1 whole Egg
2 Tablespoons Sugar
½ teaspoons Vanilla
1 teaspoon Water
In a medium bowl, combine cream cheese, sugar, 1 tablespoon flour, egg and orange zest; beat until smooth. (Be sure to use the measurements found under filling for these.) Set aside.
Stir together the glaze ingredients and set aside.
For the bread:
Cream butter and sugar (1/2 cup) until fluffy. Add salt and vanilla. Add egg yolks (save the egg whites as you'll need them later) to the sugar mixture; beat until creamy. Set aside.
In another bowl, combine flour (1 1/2 cups) and baking powder. Add this mixture, alternately with milk to egg yolk mixture.
Coat berries with 1 tablespoon flour and add them to the batter.
In a separate bowl, beat egg whites until soft peaks form. Add sugar (1/4 cup), 1 tablespoon at a time, and beat until stiff peaks form. Fold egg whites into batter.
Pour 1/2 into a floured and greased bread pan. Layer the filling over the batter and then finish with remainder of batter. This will create a layer of "cheesecake" between the blueberry batter.
Pour glaze over top of unbaked loaf and bake at 350F for 55-60 minutes.
The Keenan cookbook
I don't have a blog but my recipe is simple, this is the smoothie I made every morning and so delicious.
Peanut Butter Banana Smoothie
2 frozen bananas
1/2 cup yogurt (I used Vanilla Goat Yogurt)
¼ cup all-natural peanut butter
1 ½ cups cold almond milk (sometimes I use Almond milk to change the flavor)
Combine all ingredients in a blender and blend until smooth. Serve immediately. It's that easy!
whoops, use 1 ½ cups cold Milk or Almond milk for those who can't have dairy.
shared on FB:
I linked up my Whole Wheat Pumpkin Pie Pancakes.
I linked up my Pumpkin Pie Waffles.
I tweeted about the giveaway!
I posted on Pinterest. http://pinterest.com/pin/274790014736439562/
I love this strata, adapted from Smitten Kitchen!
Spinach and Cheese Strata
Serves 6 to 8
1 (10 ounce) package frozen, chopped spinach; thawed, squeezed of all excess liquid
1 large onion, chopped
3 tablespoons butter
a good amount of freshly ground black pepper
8 cups cubed French or Italian bread in 1-inch cubes (1/2 lb)
6 ounces coarsely grated Gruyère (2 cups)
2 ounces finely grated parmesan (1 cup)
2 3/4 cups milk
9 large eggs
2 tablespoons Dijon mustard
Sauté onion in butter until soft. Add pepper and just a dash of salt and continue cooking for one minute. Stir in spinach and remove from heat.
Spread one third of the bread cubes in a greased (butter is best) 3-quart ceramic baking dish. Top with one-third of bread cubes, one-third of spinach mixture and one-third of each cheese. Repeat layering twice with remaining bread, spinach and cheese.
Whisk eggs, milk, mustard and remaining some more salt & pepper together in a large bowl and pour evenly over strata. Cover with plastic wrap and chill strata for eat least 8 hours or up to a day.
The next day, let it stand at room temperature for 30 minutes while preheating the oven to 350°F. Bake strata, uncovered, in middle of oven until puffed, golden brown, and cooked through, 45 to 55 minutes. Let stand 5 minutes before serving.
no blog: my recipe entry-
pb mocha smoothie
blend the following until smooth and serve immediately
1c milk
1/2c strong brewed coffee
1/2c smooth peanut butter
2 T cocoa powder
1 banana
We like to make pancakes. The pancake mix is 2 cups milk, 2 cups flour, an egg, 3 tablespoons butter, a little baking powder, salt, sugar.
Another breakfast recipe I like is milk oatmeal. I use quaker oatmeal, pinch of salt, milk 1.5 times the oatmeal, cook on medium low heat for 15 minutes, afterwards mix in a tablespoon of peanut butter, sprinkle some berries and banana slices.
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I left a link to an aunt's Egg & Ham Overnight Casserole we love to make when having company. Very little morning fuss.
I also left a link to a recipe on how to make The Best Scrambled Eggs. For years we tried duplicating my mother-in-laws wonderful eggs, and then she shared her "secrets". You gotta try this!
I linked up!
I shared my recipe for Vanilla Almond Granola in the widget above. I love to enjoy a bowl of this granola, made with Real California Butter, in a bowl with cold milk!
I tweeted: Join @TidyMom & @RealCalifMilk for the #DairyBreakfastClub party Share #recipes & #WIN $250 at http://bit.ly/dairyrecipes 3/18-25
Thanks for this contest!
I posted a pic of my recipe to Instagram. I'm new to Instagram so hope I did it right. I put the hash tag in a comment. Hope you can see it. I am sebh56 on Instagram.
Thanks Cheryl for hosting this amazing party with Real California Milk ! I linked up my Skillet Breakfast Burritos! (=
Just tweeted this message!
Join @TidyMom & @RealCalifMilk for the #DairyBreakfastClub party Share #recipes & #WIN $250 at http://bit.ly/dairyrecipes 3/18-25
And…gave it some PIN action!
Just added it to my personal FB
And finally, posted it onto my FB Fan Page (=
We love these and love that they are from scratch!
Blueberry Pancakes
1 egg
1 cup milk
2 Tbsp vegetable oil
1 cup unbleached flour
3 tsp baking powder
1/4 tsp salt
2 tsp vanilla
1 cup fresh blueberries
Beat egg in mixer until fluffy. Add milk and oil and mix well. Add dry ingredients and mix well. Fold in blueberries. Cook on stovetop on medium heat. Enjoy!
1 banana
1 cup Strawberries
1cup milk
Ice and Blend
I've never measured out all the ingredients for this casserole but it is one of my kids' favorites & holds together so well that you can eat it with your hands during the morning rush 🙂
Line the bottom of a 9×13 casserole dish with frozen tater tots. Beat about 1 dozen eggs with 1 c of milk, about 1/2 t onion or garlic powder (I like using both), salt & pepper to your taste. Sprinkle 1c or so shredded cheddar cheese topped with a generous amount of fresh spinach. Pour egg mixture over top of spinach & tater tots. Top with a 2-3 T of parmesan, preferably freshly grated. Bake until firm at 350 degrees. This is a very versatile recipe and you can add diced bell peppers or onions, crumbled bacon, ground sausage or even ground beef just to name a few options. Once cooled, cut into manageable sizes & grab for on the go. My kids say this recipe is even better if made the night before & eaten warmed in the morning.
I linked up a sausage biscuit casserole!
Linked up my Honey Wheat Bran Muffins. They are delicious and healthy!
Breakfast and dairy are two of my favorite things!
Celebrate the Day Breakfast Cake (serves 6)
3/4 cup plain nonfat yogurt
1/4 cup pumpkin puree
1/8 cup lemon jiuce
1/4 cup honey
2 eggs
1 1/4 cup whole wheat pastry flour
1 crunchy apples
1 teaspoon vanilla
1 1/4 teaspoon baking powder
1/4 teaspoon baking soda
1 teaspoon cinnamon
Pinch of salt
Pinch of spices (nutmeg, ginger, allspice)
2 tablespoons butter
Heat oven to 350. Lightly grease 9 inch pan.
Cut apple into small chunks. Whisk all wet ingredients, add dry ingredients (except spices). Stir in apple chunks. Mix spices with 2 tablespoons of melted butter. Add batter to pan, pour butter over top.
Bake for 30-35 minutes (cover if getting too brown). Let stand for 15 minutes. Enjoy with a glass of milk or with mil poured over the top.
Even better the next day!
Wholesome Eggs & Veggies – serves 2
1/2 cup lowfat ricotta cheese
Fresh basil
Fresh spinach, chopped
1 cup cherry tomatoes, cut in halves
2 Whole wheat english muffins
4 eggs
Salt & Pepper to taste
Olive oil for drizzling
(optional: canadian bacon)
Mix ricotta, chopped fresh basil, and a dash of salt and pepper. Toast english muffins.
Heat 1 tablespoon of water in saucepan. When hot, add spinach to wilt. Heat a pan and saute tomatoes, add chopped basil and salt and pepper to taste. Fry eggs. If using canadian bacon, fry this as well. Put english muffins on plate. If using bacon, add this next. Put wilted spinach on top, add dollop of ricotta. Finish with an egg on top and chopped tomatoes on the side. Drizzle with olive oil.
I have linked up my Banana Bourbon Bread Pudding, Lynnette ( Nettie) Moore, Moore Or Less Cooking
I have linked up Grandmas Rice Pudding, Nettie ( Lynnette) Moore~ Moore or Less Cooking Food Blog
I have shared about this on Facebook. Nettie
I have shared on Twitter, Nettie
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Manchester United's starting line-up on the opening day of the season will be the most anticipated of any Premier League club, thanks to the appointment of a revered tactician and the new formation he has introduced.
Louis van Gaal is generating plenty of excitement, even if the club have not followed up his appointment with any major signings, bar two young talents they secured in the early part of the window.
So, how will Manchester United look in the coming season?
The Manchester United team which started the final game of last season - a 1-1 draw at Southampton for caretaker coach Ryan Giggs - contained three of the most influential players of the past decade at Old Trafford.
But Patrice Evra, Rio Ferdinand and Nemanja Vidic have all departed from the defence, and Giggs has also retired to remove the most decorated player in British football history from the midfield.
Both of these areas have been strengthened, with left-back Luke Shaw arriving from Southampton for £27m and Athletic Bilbao midfielder Ander Herrera joining from Athletic Bilbao for a fee of £29m.
Slotting them into the team based on last season's formation, United's XI for the new campaign would look something like this:
However, as pre-season has made clear, United will abandon this formation and adopt a new shape in a fundamental change to their approach.
Van Gaal has delighted in instructing journalists on his tactics since joining United and he has seemingly inspired a wider movement that is challenging the prevailing orthodoxy of 4-2-3-1. Even Harry Redknapp is now going to play 3-5-2 this season - and he's brought in Glenn Hoddle to help implement it at QPR.
United's new boss alighted on the three-at-the-back system before the World Cup and used it to devastating effect, starting off Netherlands' run to the semi-finals with an emphatic destruction of Spain. But it was almost abandoned, as Van Gaal explained: "I played this system because I believe that we are not good enough to beat Spain with our normal 4-3-3 formation,. If Van Persie wouldn't have scored the 1-1 before half-time, I would've switched back to the 4-3-3 formation."
But history twisted another way and Van Persie did score, with Netherlands establishing 3-5-2 as the new formation of the moment. Van Gaal has continued to use it during pre-season, starting with a 7-0 rout of LA Galaxy and culminating in a run of five wins in six games. As he explains, it maximises the talent at his disposal: "When you look at the quality of your players you see Rooney, Van Persie, Hernandez, Mata, Welbeck, [Marouane] Fellaini, [Ander] Herrera – a lot of players can play this system. So with this system, two strikers can play, the number 10 can play, two midfielders can play, so the specialists become the wing-backs."
Roy Hodgson describes Luke Shaw "getting fitter in global terms". Right.
— John Brewin (@JohnBrewinESPN) August 12, 2014
The two wing-backs are possibly the key point. Very early on, Van Gaal ordered Shaw to undergo individual training to build up his fitness and take him down a peg or two, but he can be expected to play given how much United paid for him.
On the right, Rafael would seem the natural fit but it is reported he will be sold, leaving Antonio Valencia as the likely choice. However, Ashley Young has also impressed in pre-season, both on the left and the right. One thing is clear: there is no room for wide midfielders who cannot defend, such as Wilfried Zaha and Nani.
Here's how United's formation is expected to work with the current players at their disposal:
Note: In practice, Mata will play in advance of Herrera and Darren Fletcher as a No. 10, though our graphic cannot reflect this)
As Van Gaal stated, this formation enables him to use both Rooney and Van Persie in their favoured positions, as well as installing Mata in the No. 10 role which brought the best out of him at Chelsea.
Fletcher has just been named vice-captain so is likely to partner Herrera in the deep roles in midfield, though Michael Carrick will also be a contender when he returns from injury and Tom Cleverley and Marouane Fellaini are further options.
However, things are rather more stretched in defence - which given the move from a four to a three is the area of the team undergoing the most critical change. In fact, as well as having only one senior specialist left wing-back, and using a winger on the right, United also have only three senior centre-backs at the club.
The young English lads. Luke Shaw, Tyler Blackett, Jesse Lingard, Michael Keane, Reece James and William Keane. #MUFC pic.twitter.com/Y98g9Nfusw — Man Utd HD Photos (@MufcHDphotos) August 5, 2014
Worryingly, Shaw, Evans and Valencia are all doubts for the first game of the season against Swansea on Saturday. If all three injuries persist - with Rafael also sidelined - Van Gaal will already have to dip into the youth ranks, telling MUTV: "We have a lot of injuries, but it's also a chance for the younger boys. We have a lot of injuries and it is not good."
Left wing-back Reece James and centre-back Tyler Blackett both impressed during pre-season and played all 90 minutes as United rounded off their pre-season preparations with a 2-1 win over Valencia at Old Trafford on Tuesday night. Van Gaal's trademark willingness to trust in youth - in evidence at Ajax, Barcelona and Bayern Munich - could see United line up against Swansea with a most unfamiliar look:
Alan Hansen once made a fool of himself by telling the great British public that "you can't win anything with kids" after an opening-day defeat for United, but we are willing to stick our necks out and say reinforcements are drastically needed if United are to reclaim their place in the top four...
United fans will hope that with just under three weeks remaining of the transfer window, vice-chairman Ed Woodward has some good news up his sleeve. Last summer was a catastrophic failure and they cannot afford to miss out on their top targets again.
The possible signing of Arturo Vidal has dragged on for weeks, Thomas Vermaelen went to Barcelona, and interest in the likes of Mats Hummels has failed to transpire into anything concrete.
Wednesday's Daily Mirror back page - "Rojo: Let me go" #tomorrowspaperstoday #bbcpapers pic.twitter.com/qPxCQRaqiT
— Nick Sutton (@suttonnick) August 12, 2014
However, there is hope. In the past 24 hours, multiple reports have suggested that a £16m deal for Sporting Lisbon's Marcos Rojo is close, with Argentina's World Cup defender reportedly refusing to train in order to force through a move to Old Trafford.
Still just 24, he would look to slot into the left side of the back three - the role originally earmarked for Vermaelen.
Do absolutely see the sense in Man Utd moving for Marcos Rojo: athletic, good size, mobile, intelligent, left footed, ideal for a back 3
— Tor-Kristian Karlsen (@karlsentk) August 12, 2014
Ajax star Daley Blind - who so impressed for Van Gaal's Netherlands at the World Cup finals - has also been persistently linked with United and those rumours are gathering pace. He excelled as a left wing-back in Brazil, memorably picking out Van Persie for his iconic header against Spain, but can also play as a member of a back three or as a central, holding midfielder.
If both players are signed before the close of the window, this is how United's team might look:
There is a third player whom United are reportedly pursuing vigorously at present: Real Madrid midfielder Angel Di Maria. Paris Saint-Germain's decision to withdraw from talks with the Argentina international has seemingly left the path clear for United to mop up and sign a wonderful player who looks to have been sacrificed in Real Madrid's relentless pursuit of superstar signings. If they do sign Di Maria, they will have acquired a very versatile player who excelled in a more central role for Madrid last season, but is also at home on the wing.
Links with Vidal also refuse to go away. The Juventus star has stated he is happy in Italy but United's finances make a deal possible and recruiting one of the finest midfielders in the game would finally address what has become a big problem position for United in recent seasons thanks to Sir Alex Ferguson's refusal to sign players and David Moyes' insistence on bringing in Fellaini.
Furthermore, Fiorentina winger/wing-back Juan Cuadrado is also the subject of United interest following his brilliant performances for Colombia at the World Cup finals with reports suggesting they have priced Barcelona out of the battle for his signature. Cuadrado is the perfect fit for the wide role on the right.
So, if vice-chairman Woodward by some miracle manages to sign Rojo, Blind, Cuadrado and one of Di Maria and Vidal, this is how Manchester United's line-up could look for the coming season:
Van Gaal said this after United's 7-0 win over LA Galaxy: "When you want to change a system, you must start at once. We don't have time to prepare for other things. The other system they can play is 4-3-3 and they have played it for many years. I can change back if the system doesn't work. With the quality of the players we have, I can play 4-3-3 with three strikers on the bench, but I want to play with two strikers."
Though the Dutchman clearly favours 3-5-2 at present, he is a great strategist and could deploy his team in more of a conventional manner. Below is a possible line up in a 4-3-3 formation. Using this shape would also open up opportunities for Adnan Januzaj, who otherwise could find his chances rather restricted, operating as a back-up to Mata in the No. 10 position.
It is a formidable-looking XI. With another tweak, United could also play in the 4-2-3-1 formation they favoured last season, though again this would prevent them playing with two central forwards - something Van Gaal relished doing at the World Cup with the precision and craft of Van Persie and the exhilarating acceleration and control of Arjen Robben.
Both of these formations would also suit Danny Welbeck, who otherwise will expect to be first replacement should either Rooney or Van Persie sustain an injury. Shinji Kagawa is also an option, if he does not leave the club before the end of the transfer window.
Everything rests on the quality of player United manage to bring in before the transfer window closes. As things stand, they possess a rather unconvincing defence and a midfield which still needs reinforcement.
If they recruit well then a return to the top four is likely; if they do not, there is a possibility Champions League football could elude them once more. Admittedly, that does seem rather unlikely with a manager of the calibre of Van Gaal in charge, but a quick look at their possible line-up to face Swansea on Saturday tells you this is a squad which still needs plenty of work.
If the 3-5-2 formation is a success then United will need five centre-backs to service it across an entire season - at the moment they have three. Much rests on the work of Ed Woodward in the next 19 days. And the clock is ticking.
Tom Adams - @tomEurosport
- Sports & Recreation
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subset: commoncrawl


text:
Planned Giving through a bequest offers many advantages to both the donor and the non-profit recipient.
A bequest often allows a donor to make a larger gift than they would be able to through other means of giving. It can also provide significant tax savings for the individual's estate. The gift is written into the donor's will, but is revocable if he or she finds it necessary make changes later on.
Bequests can include cash, real estate, securities, artwork, or any other type of property that remains in an estate. And donors can stipulate that the gift support a specific fund, or designate it as unrestricted so that we can apply it to the area in most need at the time. Large bequests are often applied to the endowment, which in turn generates important income on a continuing basis.
The Bardavon staff and officers can work with you and your estate advisors to arrange a bequest. For more information contact AnnMarie Faust, Managing Director of Administration, Development & Finance at 845.473.5288 ext.103.
© 2016 Bardavon/UPAC
Last modified: 2013-08-27 18:18:15


text:
Chocolate Covered Cherry Pie
Total Time
Prep 10 mins
Cook 2 mins
Sweet, pretty & easy to put together. I'm not a big cherry fan but I eat anything that involves chocolate. Cooking time includes chilling time.
Ingredients Nutrition
- 14 ounces sweetened condensed milk (not evaporated milk!)
- 1 cup semi-sweet chocolate chips
- 1⁄2 teaspoon salt
- 21 ounces cherry pie filling
- 1⁄4 teaspoon almond extract
- 1 (9 inch) graham cracker pie crust
- chocolate whipped cream (to garnish)
- maraschino cherry (to garnish)
- In a saucepan, combine milk, chocolate chips & salt.
- Cook and stir over very low heat just until chocolate melts. (can also use microwave to do this easily & quickly).
- Combine chocolate mixture with pie filling & extract.
- Pour into pie crust & chill 2-3 hours or until firm.
- Garnish with chocolate whipped cream (Cool Whip makes a chocolate flavor) & cherries.
Most Helpful
This pie has potential, but this recipe is WAAAAAAAAAY TOO SWEET!!
Imagine my surprise when I stumbled on this recipe that would use up 5 leftover items in my pantry or refrigerator! I had to cut the recipe in half due to the amount of cherry pie filling & sweetened condensed milk, but I was able to use up the last bits of open chocolate chip bags, a nearly empty jar of maraschino cherries & a six-pack of mini graham cracker crusts that I couldn't remember buying in the first place. lol The recipe went together very easily & it tasted great! I had to use a combination of mini semi-sweet & milk chocolate chips. But I always buy the milk chocolate cherries anyway. I actually think that the mini crusts worked out well for portion control. Once we'd finished "a whole (mini) pie", our brains were satisfied & didn't want more. We'll be making this again & again. Thanks for posting Susie!
This was so rich and so delicious. I used 1 cup of Hershey Cherry Cordial kisses instead of the plain chocolate chips and it added that extra "punch" of cherry that my family is so fond of. Mine set up fine. I served it with plain Cool Whip instead of chocolate as I thought the chocolate Cool Whip would be too much for my family. They all really liked it and it was so simple to make. Thanks SQ...


text:
Download the latest version of Voodoo II drivers according to your computer's operating system. All downloads available on this website have been scanned by the latest anti-virus software and are guaranteed to be virus and malware-free.
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text:
Update: Malaysia's Markets Rise After Election
By Jason Ng and Abhrajit Gangopadhyay
Malaysia's financial markets jumped after the incumbent National Front's general election victory, surprising many analysts who had forecasted a dive whatever the outcome.
The ruling National Front retained power with a slimmer majority in parliament, that fund managers said Monday was a comfortable enough margin to ensure policy continuity. The ruling coalition won 133 of 222 parliamentary seats, slightly less than the 140 in the previous election in 2008 .
Malaysia's markets, like many others, have been vulnerable to political risks. A surprise showing by the opposition in the 2008 general elections, when it denied the National Front its traditional two-thirds majority in parliament, triggered the first-ever trading halt in the Malaysian share market, when the benchmark Kuala Lumpur Composite Index went down to the 10% limit.
This time, a resurgent opposition posed an even stronger challenge to the ruling coalition, which has been in power since Malaysia gained independence from Britain in 1957. Citigroup had warned an opposition victory may spark doubts over the fate of several big-ticket investment projects, which could derail Malaysia's ambition to pull up alongside wealthier neighbor Singapore by 2020.
The KLCI has largely underperformed its regional peers this year, with a mere 0.34% gain so far, lagging Indonesia's 14.10% gain and Thailand's 13.44%.
But Monday, markets were staging a comeback with National Front victory. The FTSE Bursa Malaysia Kuala Lumpur Composite Index opened 4.5% higher at 1771.62 and reached a record 1826.22 bringing gains this year to 3.5%. Elsewhere, the price of 10-year Malaysian Government Securities rose, pushing the yield down to 3.348%; the U.S. dollar touched a 21-month low of 2.9860 ringgit.


text:
From butter churns to diesel tractors, the Museum's agricultural artifacts trace the story of Americans who work the land. Agricultural tools and machinery in the collections range from a John Deere plow of the 1830s to 20th-century cultivators and harvesters. The Museum's holdings also include overalls, aprons, and sunbonnets; farm photographs; milk cans and food jars; handmade horse collars; and some 200 oral histories of farm men and women in the South. Prints in the collections show hundreds of scenes of rural life. The politics of agriculture are part of the story, too, told in materials related to farm workers' unions and a group of artifacts donated by the family of the labor leader Cesar Chavez.
"Agriculture - Overview" showing 1 items.
- No Image Available
Alice Weber Photograph Albums, 1945-1948
- Notes
- Weber worked in a civilian capacity on a military base in Okinawa. Her work was connected to sheet metal. Her work took her to Guam, Japan, Hawaii and China.
- Summary
- Two photograph albums, meticulously captioned, documenting Alice Weber's travels to Okinawa, Hawaii, China and Guam, during the post-World War II years. The images depict such things as base housing and facilities, Weber's co-workers, aircraft, sheet metal shops, historic sites, agriculture (including cane, pineapple and coffee cultivation in Hawaii), native people, cities, and numerous other subjects.
- Cite as
- Alice Weber Photograph Albums, 1945-1948, Archives Center, National Museum of American History
- Date
- 1945
- 1945-1948
- 1940-1950
- photographer
- Weber, Alice
- donor
- Masters, Ruth
- Local number
- 2008.3080 (NMAH Acc.)
- Data Source
- Archives Center - NMAH


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More pictures at Brickshelf.
A pity I'm too late for the challenge, but my ordered parts came in too late. Nothing to do about it, I'm still glad I was able to finally finish my Avalonian watchtower I had in my mind.
EDIT: Added more pictures.
Edited by Matn, 18 December 2011 - 10:03 PM.


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US judge throws out Apple's case against Google-owned Motorola
Apple has suffered yet another blow in its ongoing war against Android after a US judge dismissed its case against Motorola
Apple has lost yet another legal battle against Google's Android platform after a US judge dismissed its claims that Motorola was charging excessive royalties for use of its standard-essential patents.
Motorola sought 2.25 per cent of the price of Apple products that use some of its patents — but Apple was only prepared to pay $1 per device, reports Tech Crunch.
Google officially acquired Motorola at the start of 2012 in order to get its hands on the company's treasure trove of 17,000 patents. While many of Motorola's key standard-essential patents must be licensed under FRAND (fair and non-discriminatory) terms, the leverage it gives Google over Apple is obvious.
District Judge Barbara Crabb dismissed the case on Monday after questioning whether she had the legal authority to hear Apple's claims late last week, according to Reuters.
Apple must now convince Crabb to hear its case against Motorola Mobility, although the iPhone-maker stated that it would not consider itself bound by the judge's rate if it exceeded $1 per iPhone.
'A Google spokeswoman said the company was pleased with the order, while an Apple representative declined to comment. In a legal brief filed after Crabb's ruling, Apple contended that the judge does indeed have the authority to hear its claims.'
Speaking officially on the subject, Google said Motorola has long offered licensing at reasonable rates and remains committed to 'reaching an agreement with Apple.'
Both Apple and Microsoft have now brought claims against Google regarding its patent licensing polices.
Microsoft will meet with Google-owned Motorola in a Seattle court next week but has already stated that it will live with whatever ruling is passed, which could cause problems for Apple's on-going case.


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In this thin volume the author compares vision and hearing in an effort "toward arriving at general principles of organization and theory of the whole sensorium." Brief discussion of various aspects, such as comparison of sensitivity, range of intensities, differential sensitivity, energy integration, growth and decay of sensation, the quantum theory, together with a certain amount of clinical and experimental data, is offered with a rather philosophical approach. Aside from the attempt to correlate the material on the sensory response of the two special organs involved, little new knowledge has been added. It is doubtful that this book will have a wide appeal.
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Central Emergency Response Fund
Help the UN Provide Aid
To speed up relief efforts, the UN has set up a central humanitarian fund — the Central Emergency Response Fund (CERF) — collecting contributions year-round to help ensure that funds are on-hand to allow the UN to save lives quickly.
Help the UN help in time: Donate NOW.
Every contribution can help make a difference. As a 501(c) (3) public charity, contributions made to the UN Foundation are tax deductible for U.S. donors. To donate, click here.
CERF stands for Central Emergency Response Fund. For more information on the CERF, click here.
CERF Added Value
- CERF is Fast: Humanitarian agencies faced with a sudden disaster often struggle to find resources to start life-saving operations. The time between an appeal for assistance and disbursement of funds can be long. This delay costs lives. The CERF fills this critical gap, allocating funds within days of an emergency to kick-start relief efforts.
- CERF is Fair: Decisions are based on needs on the ground, as reported by UN Humanitarian Coordinators. Furthermore, by providing humanitarian assistance to neglected emergencies, the Fund helps redress the imbalance in global aid distribution.
- CERF is Cost-effective: The CERF promotes prioritization and coordination, reducing gaps and overlaps, thus avoiding wasted resources. More importantly, fast response saves resources, as humanitarian requirements following a disaster can often increase if the situation is not contained immediately.
Related Initiatives
- UN Office for the Coordination of Humanitarian Affairs
Learn more. http://www.unocha.org
For more information on how the CERF works, please visit the CERF website or consult the CERF factsheet - in English, Arabic, Chinese, French, Russian or Spanish.


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test caption placement
Juniper Moon Farm Brekken is named after a poem by Christine DeLuca. Brekken is a triangular stockinette shawl with eyelet rows for interest. This simple shawl is easy to memorize and the perfect accessory to grab on your way out the door.
Finished measurements: 60" wide x 19" long
Yarn: 3 balls Juniper Moon Farm Marlowe Jeweltones in color #103 Green (Key Lime Pie)
Needles: US 9, long circular needle for knitting flat, or size used to obtain gauge
Gauge: 16 sts and 24 rows = 4" in St st


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Log In |
The Trucker News Services
WASHINGTON — A fourth Mexico-domiciled motor carrier has passed the Pre-Authority Safety Audit (PASA).
The Federal Motor Carrier Safety Administration will publish a formal notice Wednesday seeking comments on Baja Express Transportes of Tijuana, Baja, California, Mexico.
Comments will be accepted for 10 days after the Federal Register notice is published.
Passing the audit is the first step toward receiving operating authority to participate in the three-year cross-border demonstration pilot project.
Two other carriers who passed the safety audit — Transportes Olympic and Moises Alvarez Perez — have been granted operating authority.
A fourth carrier — Grupo Behr — passed the safety audit, but concerns about the carrier's safety record during the public comment period resulted in FMCSA not granting operating authority pending further investigation.
Eighteen other Mexico-domiciled carriers have applied for operation authority and are in various stages of the application and PASA processes.
During that investigation, FMCSA discovered violations involving the Grupo Behr leasing its vehicles to a company with authority to operate beyond the commercial zones, something not allowed under U.S. law, an FMCSA spokesperson said. FMCSA issued a Notice of Violation to the company. Grupo Behr has submitted a corrective action plan, and FMCSA intends to monitor the company's operations for six months and reconsider their application for the program at that point.
FMCSA records show Baja Express Transportes' audit includes one truck and one driver.
Baja is a new carrier and will not be in SAFER or SMS until it is granted authority, an FMCSA spokesperson said.
Two FMCSA officials went to Mexico last week to encourage more Mexico-domiciled carriers to participate in the program.
The stated objective of the pilot is to collect and evaluate data on the safety performance of Mexico-domiciled carriers.
That data would then be evaluated to determine whether the program should be made permanent.
The agency has a three-year target of 4,100 inspections. It said it would take about 46 Mexico-domiciled participating carriers to reach that target.
Juan Carlos Muñoz Márquez, the national president of Canacar, Mexico's trucking association, said the pilot "is very complicated, it's very expensive, and to tell you the truth, it hasn't brought us any benefit."
The Trucker staff can be reached to comment on this article at firstname.lastname@example.com.
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Otolaryngologists provide medical and surgical treatment for conditions of the ear, nose and throat as well as thyroid disorders, sinus surgery, skin cancers, sleep disorders and allergies in adults as well as pediatrics. Finger Lakes Health's multidisciplinary team is highly skilled in addressing conditions of the ear, nose and throat. From physician specialists to speech therapists, we offer comprehensive treatment and recovery plans that assist patients throughout the healing process.
Otolaryngology services include:
The otolaryngologists and speech pathologists associated with our medical staffs stay at the leading edge of medical knowledge and best care practices in their field: a hallmark of the Geneva General Hospital and Soldiers & Sailors Memorial Hospital medical staffs.
Major conditions include:
Rhinology (sinus diseases and anterior skull base)
Facial reconstructive surgery
Use the physician directory for more information about this service and to search for otolaryngologists affiliated with Geneva General Hospital and Soldiers & Sailors Memorial Hospital.


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Fed up with endless fees, cramped seats, long lines, and crazy connections? Use our strategies to fly saner, safer, and cheaper.
What You Need to Know About Expired EpiPens
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Meal Delivery Services Put Dinner on Your Doorstep
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PASADENA, Calif.—The California Institute of Technology (Caltech) has been rated the world's number one university in the 2012–2013 Times Higher Education global ranking of the top 200 universities.
Oxford University, Stanford University, Harvard University, and MIT round out the top five.
"We are pleased to be among the best, and we celebrate the achievements of all our peer institutions," says Caltech president Jean-Lou Chameau. "Excellence is achieved over many years and is the result of our focus on extraordinary people. I am proud of our talented faculty, who educate outstanding young people while exploring transformative ideas in an environment that encourages collaboration rather than competition."
Times Higher Education compiled the listing using the same methodology as in last year's survey. Thirteen performance indicators representing research (worth 30 percent of a school's overall ranking score), teaching (30 percent), citations (30 percent), international outlook (which includes the total numbers of international students and faculty and the ratio of scholarly papers with international collaborators, 7.5 percent), and industry income (a measure of innovation, 2.5 percent) make up the data. Included among the measures are a reputation survey of 17,500 academics; institutional, industry, and faculty research income; and an analysis of 50 million scholarly papers to determine the average number of citations per scholarly paper, a measure of research impact.
In addition to placing first overall in this year's survey, Caltech came out on top in the teaching indicator as well as in subject-specific rankings for engineering and technology and for the physical sciences.
"Caltech held on to the world's number one spot with a strong performance across all of our key performance indicators," says Phil Baty, editor of the Times Higher Education World University Rankings. "In a very competitive year, when Caltech's key rivals for the top position reported increased research income, Caltech actually managed to widen the gap with the two universities in second place this year—Stanford University and the University of Oxford. This is an extraordinary performance."
Data for the Times Higher Education's World University Rankings were provided by Thomson Reuters from its Global Institutional Profiles Project, an ongoing, multistage process to collect and validate factual data about academic institutional performance across a variety of aspects and multiple disciplines.
The Times Higher Education site has the full list of the world's top 400 schools and all of the performance indicators.
PASADENA, Calif.—Sarkis Mazmanian, a microbiology expert at the California Institute of Technology (Caltech) whose studies of human gut bacteria have revealed new insights into how these microbes can be beneficial, was named a MacArthur Fellow and awarded a five-year, $500,000 "no strings attached" grant. Each year, the John D. and Catherine T. MacArthur Foundation awards the unrestricted fellowships—also known as "genius" grants—to individuals who have shown "extraordinary originality and dedication in their creative pursuits and a marked capacity for self-direction," according to the foundation's website.
"I was in a state of shock when I heard the news," says Mazmanian, a professor of biology at Caltech, who was tricked into taking the award announcement call; he thought he was simply being added to a prescheduled conference call. "It's not the kind of thing you ever expect—I do what I do because I love science and it makes me happy, so this is terrific and a nice reward. At the same time, I never think of awards as goals of mine because they seem so unattainable. My goals are to make discoveries, so I was just in absolute disbelief."
Long before he was named a 2012 MacArthur Fellow, Mazmanian was showing the attributes that the foundation seeks to reward, particularly a capacity for self-direction. As a graduate student in the in the early 2000s, he decided to stray from the normal path of study and try something new.
"I had been studying microbial pathogenesis—or bacteria that make us sick—which is what 99.9 percent of the field of microbiology does to this day," says Mazmanian. "Toward the end of my PhD, I decided that I wanted to study organisms that didn't necessarily cause disease, but were associated with our bodies. Ten years ago, this was completely on the fringe of science—we knew that the organisms existed in our intestines and all over our bodies, but had no idea what they were doing."
Today, Mazmanian's work examines some of the trillions of bacteria living in our bodies that make up complex communities of microbes and regulate processes like digestion and immunity. His main focus is to understand how "good" bacteria promote human health—work that has transformed a quickly evolving field of research that is investigating the connection between gut bacteria and their relationship to both disease and health.
Medical Microbiologist Sarkis Mazmanian: 2012 MacArthur Fellow | MacArthur Foundation
His research helped lay the groundwork for the Human Microbiome Project (HMP), an initiative of the National Institutes of Health that aims to characterize, for the first time, "the microbial communities found at several different sites on the human body, including nasal passages, oral cavities, skin, gastrointestinal tract, and urogenital tract, and to analyze the role of these microbes in human health and disease," according to the HMP website.
His laboratory was the first to demonstrate that specific gut bacteria direct the development of the mammalian immune system and provide protection from intestinal diseases. This means, he says, that fundamental aspects of health are absolutely dependent on microbial interaction within our bodies. In addition, he says that many disorders whose incidences are increasing in Western countries—such as inflammatory bowel disease, multiple sclerosis, and asthma—involve a common immunologic defect believed to be caused by the absence of intestinal bacteria. An understanding of the beneficial immune responses promoted by gut bacteria may lead to the development of natural therapeutics for immunologic and perhaps neurologic diseases, says Mazmanian.
"This award is extremely well-deserved—Sarkis has revolutionized the way we think about the interactions between microorganisms and people," says Stephen L. Mayo, William K. Bowes Jr. Foundation Chair of Caltech's Division of Biology, and Bren Professor of Biology and Chemistry. "His research has had an important impact in making the connection between personal hygiene and the immune system, and even neurological diseases like autism."
When the award announcement went public, Mazmanian was in Armenia, his native homeland, teaching a one-week course on host-microbial interaction to PhD students at a molecular biology institute. He travels to the country once a year to volunteer his services. The timing, he says, couldn't be better, as he hopes to use some of the prize money to develop an international educational outreach program.
"I think that when you have a windfall like this, the least you can do is help people who are in need," says Mazmanian, who credits the members of his lab for his research success. "In many countries, they are in need of education and resources, like lab equipment, text books, you name it. It would be a terrific if I could use the money to help advance science in countries where there is hardship."
Mazmanian received his bachelor's degree in 1995 and his PhD in microbiology in 2002, both from UCLA. Following a postdoctoral fellowship at Harvard, he joined the Caltech faculty as an assistant professor in 2006. In 2012, he was promoted to professor of biology. In 2011, Mazmanian was the recipient of a Burroughs Welcome Fund award for research in the pathogenesis of infectious disease, and in 2008 he was awarded a Searle Scholarship and was named one of Discover magazine's "20 Best Brains Under 40," which highlighted young innovators in science.
This year's crop of 23 Fellows includes stringed-instrument bow maker Benoît Rolland and mathematician Maria Chudnovsky; Mazmanian joins the ranks of Caltech's previous MacArthur Fellows, including 2010 awardee John Dabiri.
For more information on the 2012 MacArthur Fellows, visit the foundation website at www.macfound.org.
PASADENA, Calif.—As the saying goes, "A picture is worth a thousand words." For people in certain professions—acting, modeling, and even politics—this phrase rings particularly true. Previous studies have examined how our social judgments of pictures of people are influenced by factors such as whether the person is smiling or frowning, but until now one factor has never been investigated: the distance between the photographer and the subject. According to a new study by researchers at the California Institute of Technology (Caltech), this turns out to make a difference—close-up photo subjects, the study found, are judged to look less trustworthy, less competent, and less attractive.
The new finding is described in this week's issue of the open-access journal PLoS One.
Pietro Perona, the Allen E. Puckett Professor of Electrical Engineering at Caltech, came up with the initial idea for the study. Perona, an art history enthusiast, suspected that Renaissance portrait paintings often featured subtle geometric warping of faces to make the viewer feel closer or more distant to a subject. Perona wondered if the same sort of warping might affect photographic portraits—with a similar effect on their viewers—so he collaborated with Ralph Adolphs, Bren Professor of Psychology and Neuroscience and professor of biology, and CNS graduate student Ronnie Bryan (PhD '12) to gather opinions on 36 photographs representing two different images of 18 individuals. One of each pair of images was taken at close range and the second at a distance of about seven feet.
"It turns out that faces photographed quite close-up are geometrically warped, compared to photos taken at a larger distance," explains Bryan. "Of course, the close picture would also normally be larger, higher resolution and have different lighting—but we controlled for all of that in our study. What you're left with is a warping effect that is so subtle that nobody in our study actually noticed it. Nonetheless, it's a perceptual clue that influenced their judgments."
That subtle distance warping, however, had a big effect: close-up photos made people look less trustworthy, according to study participants. The close-up photo subjects were also judged to look less attractive and competent.
"This was a surprising, and surprisingly reliable, effect," says Adolphs. "We went through a bunch of experiments, some testing people in the lab, and some even over the Internet; we asked participants to rate trustworthiness of faces, and in some experiments we asked them to invest real money in unfamiliar people whose faces they saw as a direct measure of how much they trusted them."
Across all of the studies, the researchers saw the same effect, Adolphs says: in photos taken from a distance of around two feet, a person looked untrustworthy, compared to photos taken seven feet away. These two distances were chosen by the researchers because one is within, and the other outside of, personal space—which on average is about three to four feet from the body.
In some of the studies, the researchers digitally warped images of faces taken at a distance to artificially manipulate how trustworthy they would appear. "Once you know the relation between the distance warp and the trustworthiness judgment, you could manipulate photos of faces and change the perceived trustworthiness,'' notes Perona.
He says that the group is now planning to build on these findings, using machine-vision techniques—technologies that can automatically analyze data in images. For example, one application would be for a computer program to have the ability to evaluate any face image in a magazine or on the Internet and to estimate the distance at which the photo was taken.
"The work might also allow us to estimate the perceived trustworthiness of a particular face image," says Perona. "You could imagine that many people would be interested in such applications—particularly in the political arena."
The study, "Perspective Distortion from Interpersonal Distance Is an Implicit Visual Cue for Social Judgments of Faces," was funded by grants from the National Institute of Mental Health and from the Gordon and Betty Moore Foundation.
PASADENA, Calif.—At any given moment, millions of cells are on the move in the human body, typically on their way to aid in immune response, make repairs, or provide some other benefit to the structures around them. When the migration process goes wrong, however, the results can include tumor formation and metastatic cancer. Little has been known about how cell migration actually works, but now, with the help of some tiny worms, researchers at the California Institute of Technology (Caltech) have gained new insight into this highly complex task.
The team's findings are outlined this week online in the early edition of the Proceedings of the National Academy of Sciences (PNAS).
"In terms of cancer, we know how to find primary tumors and we know when they're metastatic, but we're missing information on the period in between when cells are crawling around, hanging out, and doing who knows what that leads to both of these types of diseases," says Paul Sternberg, Thomas Hunt Morgan Professor of Biology at Caltech, and corresponding author of the paper.
To learn more about those crawling, or migrating, cells, Sternberg looked at the animal he knows best—the tiny Caenorhabditis elegans, a common species of roundworm that he has been studying for many years. Despite their small size, the worms actually share quite a few genes with humans.
"Migration is such a conserved process," says Mihoko Kato, a senior research fellow in biology at Caltech and a coauthor of the paper. "So whether it happens in C. elegans or in mammals, like humans, we think that many of the same genes are going to be involved."
Contained in each cell—be it human or worm—are thousands of genes, all of which have a special job, or jobs, to do. Of these genes, roughly one-third are active in a given cell. To see what genes are expressed during migration, Sternberg and Kato, along with Erich Schwarz, a research fellow in Sternberg's lab, studied a single cell, called the linker cell (LC), in the worms; during reproductive development, LCs travel almost the entire length of the worm's body.
Using high-powered microscopy, the team identified LCs at two intervals, 12 hours apart, during the worm's larval stage, and removed them from the animals. Then, using sequencing and computational analysis, they determined the genes that were actively expressed at these two migration time points. This method of study is called transcriptional profiling.
"By understanding the normal migration of a single cell, we can understand something about how the cells are programmed to navigate their environment," says Sternberg, who is also an investigator with the Howard Hughes Medical Institute. "Our view of cancer metastasis is that the tumor cells confront some obstacle and then they have to evolve to get through or around that obstacle. The way they probably do that is by using some aspect of the normal program that exists somewhere in the genome."
He says that learning more about different ways that cells migrate may lead to the development of new types of drugs that block this process by targeting specific genes. The team plans additional transcriptional profiling studies to obtain more detailed information about the functions of particular C. elegans genes involved in migration—and, eventually, of similar genes in higher organisms, including humans.
"We selected genes present in both worms and humans, but which have not been studied much before us," says Schwarz. "Since we found that some of these genes help worm LCs migrate, we think each one may have a related human gene helping cells migrate, too."
"The nice thing about this technology is that you can use it with any cell type," adds Kato, who points out that their studies have already helped identify new functions for known genes possessed by both the worms and humans. "It's a similar process to do transcriptome profiling using human cells."
In addition to identifying drug targets, the team is also hoping to find a good signature, or molecular marker, for migrating cells. "This kind of information could be very useful diagnostically, to help identify cells that are doing things that they shouldn't be doing, or weird combinations of genes that shouldn't be expressed together, which is what a tumor cell might have," says Sternberg. "This work lays the foundation for really understanding what information is critically needed from mammalian cells for tumor cells to be able to migrate."
The study, "Functional transcriptomics of a migrating cell in Caenorhabditis elegans," was funded by the National Institutes of Health and the Howard Hughes Medical Institute.
Two members of the California Institute of Technology (Caltech) faculty have been given National Institutes of Health (NIH) Director's Awards. The awards are administered through the NIH's Common Fund, which provides support for research deemed to be both innovative and risky.
"The Common Fund High Risk–High Reward program provides opportunities for innovative investigators in any area of health research to take risks when the potential impact in biomedical and behavioral science is high," said NIH Director Francis S. Collins in a press release.
There are three types of NIH Director's Awards: the Pioneer Award, the New Innovator Award, and the Transformative Research Award. This year, biologist Doris Ying Tsao was given one of 10 Pioneer Awards, and geobiologist Dianne K. Newman was among the 20 scientists to receive Transformative Research Awards.
The Pioneer Award, established in 2004, "challenges investigators at all career levels to develop highly innovative approaches that have the potential to produce a high impact on a broad area of biomedical or behavioral research," according to the NIH. Tsao, an assistant professor of biology, will explore the question of how objects that we see are initially processed in the brain.
"The retina essentially transmits an array of unconnected pixels to the brain. These are first processed locally, through various local filters for color, motion, etc., and the image does not yet contain objects, or bound units," says Tsao. "But after this, there is a mysterious operation that puts all these local pieces together for the first time—and that is what I am studying. I want to know how the brain dynamically links all these pixels over space and time, based on surface contiguity, to form bound units."
For example, as a truck makes a U-turn, the pixels defining the truck can change completely, yet we have no trouble tracking those pixels and seeing they belong to a single invariant object, she explains.
"I am incredibly excited to have the chance, with the NIH Pioneer Award, to hunt for the circuits implementing these computations within the brain," says Tsao. "We just have to open our eyes to know the circuits exist, but understanding them is going to be an immense challenge that will require huge resources, and to now suddenly have these resources is unbelievable to me."
The Transformative Research Award program, established in 2009, "promotes cross-cutting, interdisciplinary approaches" for research that "has the potential to create or overturn fundamental paradigms," according to the NIH. Newman, professor of biology and geobiology, will use the award to apply geobiological approaches to understanding the progression of pulmonary infections.
Due to the challenges of working in situ, or in the body, most studies of infectious disease agents are conventionally performed with representative isolates and imperfect disease models in the laboratory, says Newman. Very few direct measurements of the physiological state of drug-tolerant populations in the host exist, and little is known about which metabolic pathways are actually in play, much less how they change over time in response to coevolving conditions within the lung, she explains.
"We will tackle this critical knowledge gap using an approach inspired by geobiology," says Newman, who is also an investigator with the Howard Hughes Medical Institute. "Geobiologists are experienced in studying the growth and metabolism of microbial populations in poorly accessible natural habitats by combining molecular biology and stable isotope geochemistry; we will apply these tools to the lung."
The goal of this project, she says, is to lay a foundation for novel therapeutics to modify and control infectious disease agents.
"I am honored to have received this award because it will take our research in a meaningful new direction," says Newman. "The opportunity to collaborate with an outstanding group of colleagues at Caltech and at USC and Johns Hopkins hospitals is very exciting. I'm grateful that the NIH took a chance on our idea, and I hope it fulfills its promise."
PASADENA, Calif.—As an animal develops from an embryo, its cells take diverse paths, eventually forming different body parts—muscles, bones, heart. In order for each cell to know what to do during development, it follows a genetic blueprint, which consists of complex webs of interacting genes called gene regulatory networks.
Biologists at the California Institute of Technology (Caltech) have spent the last decade or so detailing how these gene networks control development in sea-urchin embryos. Now, for the first time, they have built a computational model of one of these networks.
This model, the scientists say, does a remarkably good job of calculating what these networks do to control the fates of different cells in the early stages of sea-urchin development—confirming that the interactions among a few dozen genes suffice to tell an embryo how to start the development of different body parts in their respective spatial locations. The model is also a powerful tool for understanding gene regulatory networks in a way not previously possible, allowing scientists to better study the genetic bases of both development and evolution.
"We have never had the opportunity to explore the significance of these networks before," says Eric Davidson, the Norman Chandler Professor of Cell Biology at Caltech. "The results are amazing to us."
The researchers described their computer model in a paper in the Proceedings of the National Academy of Sciences that appeared as an advance online publication on August 27.
The model encompasses the gene regulatory network that controls the first 30 hours of the development of endomesoderm cells, which eventually form the embryo's gut, skeleton, muscles, and immune system. This network—so far the most extensively analyzed developmental gene regulatory network of any animal organism—consists of about 50 regulatory genes that turn one another on and off.
To create the model, the researchers distilled everything they knew about the network into a series of logical statements that a computer could understand. "We translated all of our biological knowledge into very simple Boolean statements," explains Isabelle Peter, a senior research fellow and the first author of the paper. In other words, the researchers represented the network as a series of if-then statements that determine whether certain genes in different cells are on or off (i.e., if gene A is on, then genes B and C will turn off).
By computing the results of each sequence hour by hour, the model determines when and where in the embryo each gene is on and off. Comparing the computed results with experiments, the researchers found that the model reproduced the data almost exactly. "It works surprisingly well," Peter says.
Some details about the network may still be uncovered, the researchers say, but the fact that the model mirrors a real embryo so well shows that biologists have indeed identified almost all of the genes that are necessary to control these particular developmental processes. The model is accurate enough that the researchers can tweak specific parts—for example, suppress a particular gene—and get computed results that match those of previous experiments.
Allowing biologists to do these kinds of virtual experiments is precisely how computer models can be powerful tools, Peter says. Gene regulatory networks are so complex that it is almost impossible for a person to fully understand the role of each gene without the help of a computational model, which can reveal how the networks function in unprecedented detail.
Studying gene regulatory networks with models may also offer new insights into the evolutionary origins of species. By comparing the gene regulatory networks of different species, biologists can probe how they branched off from common ancestors at the genetic level.
So far, the researchers have only modeled one gene regulatory network, but their goal is to model the networks responsible for every part of a sea-urchin embryo, to build a model that covers not just the first 30 hours of a sea urchin's life but its entire embryonic development. Now that this modeling approach has been proven effective, Davidson says, creating a complete model is just a matter of time, effort, and resources.
The title of the PNAS paper is "Predictive computation of genomic logic processing functions in embryonic development." In addition to Peter and Davidson, the other author on the PNAS paper is Emmanuel Faure, a former Caltech postdoctoral scholar who is now at the École Polytechnique in France. This work was supported by the National Institute of Child Health and Human Development and the National Institute of General Medical Sciences.
PASADENA, Calif.—Scientists at the California Institute of Technology (Caltech) pioneered the study of the link between irregularities in the immune system and neurodevelopmental disorders such as autism a decade ago. Since then, studies of postmortem brains and of individuals with autism, as well as epidemiological studies, have supported the correlation between alterations in the immune system and autism spectrum disorder.
What has remained unanswered, however, is whether the immune changes play a causative role in the development of the disease or are merely a side effect. Now a new Caltech study suggests that specific changes in an overactive immune system can indeed contribute to autism-like behaviors in mice, and that in some cases, this activation can be related to what a developing fetus experiences in the womb.
The results appear in a paper this week in the Proceedings of the National Academy of Sciences (PNAS).
"We have long suspected that the immune system plays a role in the development of autism spectrum disorder," says Paul Patterson, the Anne P. and Benjamin F. Biaggini Professor of Biological Sciences at Caltech, who led the work. "In our studies of a mouse model based on an environmental risk factor for autism, we find that the immune system of the mother is a key factor in the eventual abnormal behaviors in the offspring."
The first step in the work was establishing a mouse model that tied the autism-related behaviors together with immune changes. Several large epidemiological studies—including one that involved tracking the medical history of every person born in Denmark between 1980 and 2005—have found a correlation between viral infection during the first trimester of a mother's pregnancy and a higher risk for autism spectrum disorder in her child. To model this in mice, the researchers injected pregnant mothers with a viral mimic that triggered the same type of immune response a viral infection would.
"In mice, this single insult to the mother translates into autism-related behavioral abnormalities and neuropathologies in the offspring," says Elaine Hsiao, a graduate student in Patterson's lab and lead author of the PNAS paper.
The team found that the offspring exhibit the core behavioral symptoms associated with autism spectrum disorder—repetitive or stereotyped behaviors, decreased social interactions, and impaired communication. In mice, this translates to such behaviors as compulsively burying marbles placed in their cage, excessively self grooming, choosing to spend time alone or with a toy rather than interacting with a new mouse, or vocalizing ultrasonically less often or in an altered way compared to typical mice.
Next, the researchers characterized the immune system of the offspring of mothers that had been infected and found that the offspring display a number of immune changes. Some of those changes parallel those seen in people with autism, including decreased levels of regulatory T cells, which play a key role in suppressing the immune response. Taken together, the observed immune alterations add up to an immune system in overdrive—one that promotes inflammation.
"Remarkably, we saw these immune abnormalities in both young and adult offspring of immune-activated mothers," Hsiao says. "This tells us that a prenatal challenge can result in long-term consequences for health and development."
With the mouse model established, the group was then able to test whether the offspring's immune problems contribute to their autism-related behaviors. In the most revealing test of this hypothesis, the researchers were able to correct many of the autism-like behaviors in the offspring of immune-activated mothers by giving the offspring a bone-marrow transplant from typical mice. The normal stem cells in the transplanted bone marrow not only replenished the immune system of the host animals but altered their autism-like behavioral impairments.
The researchers emphasize that because the work was conducted in mice, the results cannot be readily extrapolated to humans, and they certainly do not suggest that bone-marrow transplants should be considered as a treatment for autism. They also have yet to establish whether it was the infusion of stem cells or the bone-marrow transplant procedure itself—complete with irradiation—that corrected the behaviors.
However, Patterson says, the results do suggest that immune irregularities in children could be an important target for innovative immune manipulations in addressing the behaviors associated with autism spectrum disorder. By correcting these immune problems, he says, it might be possible to ameliorate some of the classic developmental delays seen in autism.
In future studies, the researchers plan to examine the effects of highly targeted anti-inflammatory treatments on mice that display autism-related behaviors and immune changes. They are also interested in considering the gastrointestinal (GI) bacteria, or microbiota, of such mice. Coauthor Sarkis Mazmanian, a professor of biology at Caltech, has shown that gut bacteria are intimately tied to the function of the immune system. He and Patterson are investigating whether changes to the microbiota of these mice might also influence their autism-related behaviors.
Along with Patterson, Hsiao, and Mazmanian, additional Caltech coauthors on the PNAS paper, "Modeling an autism risk factor in mice leads to permanent immune dysregulation," are Mazmanian lab manager Sara McBride and former graduate student Janet Chow. The work was supported by an Autism Speaks Weatherstone Fellowship, National Institutes of Health Graduate Training Grants, a Weston Havens Foundation grant, a Gregory O. and Jennifer W. Johnson Caltech Innovation Fellowship, a Caltech Innovation grant, and a Congressionally Directed Medical Research Program Idea Development Award.
PASADENA, Calif.—The California Institute of Technology (Caltech) and UCLA have launched highly productive collaborations in cancer research and other areas of biomedicine in recent years, frequently through the Caltech lab of Nobel Laureate and President Emeritus David Baltimore. Now, an endowment established by the Raymond and Beverly Sackler Foundation will strengthen the Caltech-UCLA partnership and advance the Baltimore lab's interdisciplinary research into areas where mathematics and engineering converge with biology.
The Sackler endowment will support three primary areas: postdoctoral researchers working in areas that have a convergent theme; students pursuing a joint MD/PhD degree through the Caltech-UCLA Medical Scientist Training Program; and a joint seminar series between Caltech and UCLA emphasizing the interface of medicine, engineering, and the physical sciences.
"Caltech has a strong interdisciplinary focus that is fueling its outstanding achievements in biomedical research," says Caltech's president Jean-Lou Chameau. "The support from the Raymond and Beverly Sackler Foundation further enhances this research, which can lead to therapies for some of the world's most critical diseases."
The research supported by the endowment will encompass many of the numerous disciplines that have become intertwined with biology in recent years, such as computational mathematics and physics. There is also an important educational component, as the Sackler endowment will help train MD/PhD students and strengthen the link between Caltech's basic science expertise and UCLA's translational medicine focus.
"The Sackler gift is very important because it allows us to expand our research in a direction in which I very much want it to go, and at the same time it will support our very significant MD/PhD program," says Baltimore, the Robert Andrews Millikan Professor of Biology. "We are grateful to Raymond and Beverly Sackler for their generosity and for their foresight in recognizing the importance of our work."
Dr. Raymond Sackler is a physician, entrepreneur, and philanthropist who has supported numerous scientific and cultural initiatives throughout the world. With his late brothers, Arthur and Mortimer, he sponsored the Sackler Faculty of Medicine, and with his wife, Beverly, has sponsored the Raymond and Beverly Sackler Faculty of Exact Sciences, both at Tel Aviv University. David Baltimore and Caltech are one of 10 recipients of endowments from the foundation as part of a recent global program in support of convergent research.
"The purpose of this gift is to catalyze new convergent science investigations and to honor the important research that has been carried out by David Baltimore," says Raymond Sackler. "He made groundbreaking scientific accomplishments at a relatively early age, and now—working at the crossroads of several disciplines—he continues to make major discoveries in biomedical research. We hope that this new endowment will foster his research and Caltech's dynamic collaborations with UCLA."
Baltimore is best known for his work with viruses and the immune system, and he shared the Nobel Prize in Physiology or Medicine in 1975 for his discoveries concerning cancer-inducing viruses. Several years ago, he decided that his research should move toward translational applications, and in 2009 he became the director of a new effort with UCLA—the Joint Center for Translational Medicine—which supports numerous research projects with the potential for clinical applications.
PASADENA, Calif.—Stephen L. Mayo, chair of the Division of Biology and Bren Professor of Biology and Chemistry at the California Institute of Technology (Caltech), has been named the William K. Bowes Jr. Foundation Division Chair. The William K. Bowes, Jr. Foundation, based in San Francisco, endowed the new division leadership chair with a $5 million gift, supplemented by an additional $2.5 million provided by the Gordon and Betty Moore Matching Program.
The new chair is named after the philanthropic foundation created by William K. Bowes, Jr., founding partner of U.S. Venture Partners in Silicon Valley. For nearly 50 years, Bowes has helped launch numerous biotechnology and other high-tech companies, including Amgen, Applied Biosystems, and Sun Microsystems.
Unlike typical professorships, which fund salaries, the Bowes Foundation Chair—also called a leadership chair—is a permanent endowment that will provide funds that Mayo and future biology division chairs will use to support innovative research projects with potential for scientific and societal impact. It will also be used to support Caltech's education mission and outreach programs.
"The Bowes Chair is unprecedented at Caltech and will be a tremendous asset to advance our science and engineering research and teaching," says Caltech president Jean-Lou Chameau. "This is the first in what will be a series of leadership chairs providing high-leverage, unrestricted support that the faculty who head our divisions will use to seed the Institute's most ambitious educational and research ideas. We are extremely grateful for Bill Bowes's inspirational and generous support."
Bowes has been connected with Caltech for more than 30 years, most notably through the founding of Amgen, which included Caltech biologists Norman Davidson and Leroy Hood as two of its scientific founders; they were also original members of the company's scientific advisory board. "I have known firsthand for years that Caltech faculty have the unique intellectual skills, imagination, and track record to propel promising entrepreneurial ventures," says Bowes. "With the Bowes Foundation Division Chair, I hope to give Caltech's extremely talented biological scientists the freedom to turn more of their ideas into reality. This is really a carefully considered investment in the future."
"Bill Bowes's important gift will give Caltech's biology division critical unrestricted funding to foster valuable research, teaching, and outreach programs," says Mayo. "It is an honor to be named the first Bowes Foundation Division Chair, not only because this is such a groundbreaking initiative for Caltech, but also because Bill has been so instrumental in launching entrepreneurial ventures that have improved so many people's lives."
Bowes has had both a varied and an influential career. After service in the Army infantry in the South Pacific and Japan during and after World War II, Bowes received a BA in economics from Stanford and then an MBA from Harvard. He was an investment banker in San Francisco for nearly three decades before founding U.S. Venture Partners in 1981. He founded and served as the first chairman and treasurer of Amgen, which would become the world's largest biotech company.
U.S. Venture Partners has played a leading role in the development of the software, health-care, and e-commerce industries, building companies such as Sun Microsystems and Applied Biosystems. It has also been one of the leading investors in Caltech start-ups, including Axiom Microdevices, Cleave Biosciences, Contour Energy Systems, and Proteolix. (For more on these companies, see "A Snapshot of Start-ups.")
In recent years, Bowes has focused his energies on philanthropy, supporting nonprofit organizations in such areas as medical research, higher education, and the environment. He has also served on numerous committees and boards for a broad range of institutions, including the Environmental Defense Fund, the San Francisco Exploratorium, the Hoover Institution, and the San Francisco Conservatory of Music.
"Bill Bowes has not only been one of the nation's pioneers in venture capital, but he has also demonstrated the effectiveness of prudent investing in philanthropy," says Caltech senior trustee William Davidow, founding partner of Mohr Davidow Ventures, a venture-capital firm based in Menlo Park. "The early experimental research that Bill is supporting today at Caltech will become the innovative entrepreneurial enterprises of tomorrow."
Steve Mayo is a pioneer in protein-design technology, having been the first to design a protein on a computer and then build it in a lab. Working at the interface of theory, computation, and wet-laboratory experimentation, Mayo focuses on developing quantitative approaches to protein engineering, aiming to understand the physical and chemical determinants of protein structure, stability, and function.
His design approach has been incorporated in a suite of software programs called Comprehensive Protein Design Software, and has been applied to a variety of problems ranging from protein fold stabilization to enzyme design. The end goal, he says, is to create protein-based therapies against diseases, new ways of improving agricultural production, and other applications. Mayo has founded or cofounded several companies, including Molecular Simulations, Xencor, and Protabit.
Caltech has a distinguished history of discovery in the biological sciences, recognized by numerous Nobel Prizes. Over its more than 75 years, Caltech's Division of Biology has made many of the research advances that led to the biotechnology and genetic revolutions. In the past, Caltech's biologists made fundamental insights in cellular and molecular biology; today our investigators are both continuing to blaze that path of discovery and applying their knowledge to finding innovative solutions to cancer, AIDS, and other diseases.
PASADENA, Calif.—Researchers at the California Institute of Technology (Caltech) have been able, for the first time, to watch viruses infecting individual bacteria by transferring their DNA, and to measure the rate at which that transfer occurs. Shedding light on the early stages of infection by this type of virus—a bacteriophage—the scientists have determined that it is the cells targeted for infection, rather than the amount of genetic material within the viruses themselves, that dictate how quickly the bacteriophage's DNA is transferred.
"The beauty of our experiment is we were able to watch individual viruses infecting individual bacteria,"says Rob Phillips, the Fred and Nancy Morris Professor of Biophysics and Biology at Caltech and the principal investigator on the new study. "Other studies of the rate of infection have involved bulk measurements. With our methods, you can actually watch as a virus shoots out its DNA."
The new methods and results are described in a paper titled "A Single-Molecule Hershey–Chase Experiment," which will appear in the July 24 issue of the journal Current Biology and currently appears online. The lead authors of that paper, David Van Valen and David Wu, completed the work while graduate students in Phillips's group.
In the well-known 1952 Hershey-Chase experiment, Alfred Hershey and Martha Chase of the Carnegie Institution of Washington in Cold Spring Harbor convincingly confirmed earlier claims that DNA—and not protein—was the genetic material in cells. To prove this, the researchers used bacteriophages, which are able to infect bacteria using heads of tightly bundled DNA coated in a protein shell. Hershey and Chase radiolabeled sulfur, contained in the protein shell but not in the DNA, and phosphorous, found in the DNA but not in the protein shell. Then they let the bacteriophages infect the bacterial cells. When they isolated the cells and analyzed their contents, they found that only the radioactive phosphorous had made its way into the bacteria, proving that DNA is indeed the genetic material. The results also showed that, unlike the viruses that infect humans, bacteriophages transmit only their genetic information into their bacterial targets, leaving their "bodies" behind.
"This led, right from the get-go, to people wondering about the mechanism—about how the DNA gets out of the virus and into the infected cell," Phillips says. Several hypotheses have focused on the fact that the DNA in the virus is under a tremendous amount of pressure. Indeed, previous work has shown that the genetic material is under more pressure within its protein shell than champagne experiences in a corked bottle. After all, as Phillips says, "There are 16 microns of DNA inside of a tiny 0.05 micron-sized shell. It's like taking 500 meters of cable from the Golden Gate Bridge and putting it in the back of a FedEx truck."
Phillips's group wanted to find out whether that pressure plays a dominant role in transferring the DNA. Instead, he says, "What we discovered is that the thing that mattered most was not the pressure in the bacteriophage, but how much DNA was in the bacterial cell."
The researchers used a fluorescent dye to stain the DNA of two mutants of a bacteriophage known as lambda bacteriophage—one with a short genome and one with a longer genome—while that DNA was still inside the phage. Using a fluorescence microscope, they traced the glowing dye to see when and over what time period the viral DNA transferred from each phage into an E. coli bacterium. The mean ejection time was about five minutes, though that time varied considerably.
This was markedly different from what the group had seen previously when they ran a similar experiment in a test tube. In that earlier setup, they had essentially tricked the bacteriophages into ejecting their DNA into solution—a task that the phages completed in less than 10 seconds. In that case, once the phage with the longer genome had released enough DNA to make what remained inside the phage equal in length to the shorter genome, the two phages ejected DNA at the same rate. Therefore, Phillips's team reasoned, it was the amount of DNA in the phage that determined how quickly the DNA was transferred.
But Phillips says, "What was true in the test tube is not true in the cell." E. coli cells contain roughly 3 million proteins within a box that is roughly one micron on each side. Less than a hundredth of a micron separates each protein from its neighbors. "There's no room for anything else," Phillips says. "These cells are really crowded."
And so, when the bacteriophages try to inject their DNA into the cells, the factor that limits the rate of transfer is how jam-packed those cells are. "In this case," Phillips says, "it had more to do with the recipient, and less to do with the pressure that had built up inside the phage."
Looking toward the future, Phillips is interested in using the methods he and his team have developed to study different types of bacteriophages. He also wants to investigate various molecules that could be helping to actively pull the viral DNA into the cells. In the case of a bacteriophage called T7, for instance, previous work has shown that the host cell actually grabs onto the DNA and begins making copies of its genes before the virus has even delivered all the DNA into the cell. "We're curious whether that kind of mechanism is in play with the lambda bacteriophage," Phillips says.
The current findings have implications for the larger question of how biomolecules like DNA and proteins cross membranes in general, and not just into bacteria. Cells are full of membranes that divide them into separate compartments and that separate entire cells from the rest of the world. Much of the business of cellular life involves getting molecules across those barriers. "This process that we've been studying is one of the most elementary examples of what you could call polymer translocation or getting macromolecules across membranes," Phillips says. "We are starting to figure out the physics behind that process."
In addition to Phillips, Van Valen, and Wu, the other authors on the Current Biology paper are graduate student Yi-Ju Chen; Hannah Tuson of the University of Wisconsin at Madison; and Paul Wiggins of the University of Washington. Van Valen is currently a medical student at UCLA's David Geffen School of Medicine, and Wu is an intern at the University of Chicago. The work was supported by funding from the National Science Foundation, a National Institutes of Health Medical Scientist Training Program fellowship, a Fannie and John Hertz Yaser Abu-Mostafa Graduate Fellowship, and an NIH Director's Pioneer Award.


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Why doesn't blood sink to your feet?
QuestionOne from my boy – when you do a handstand, all the blood rushes to your head, but when you stand up, it doesn't sink to your feet. Why?
Chris, Bromley
** Definitive **
Name: James O'Brien
Qualification: Mystery Hour legend
Answer: It's because we are designed to be upright. When we go upside down it's unusual, but our heart is designed to pump blood around the body when we are the right way up.
** Scientific Definitive **
Name: Fred, Guildford
Qualification: Bloody good!
Answer: You have one-way valves in your thighs and calves which stop the blood going back up. So when you are upside down, the blood cannot get through those valves.
Do you agree? Send us your answer in the box below…


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Five fun runs & obstacle courses
Step up your fall fitness with the Mud Run, Color Run, Electric Run & more
Del Mar Mud Run at the Del Mar Fairgrounds – October 5
A little dirt never hurt, and at this annual Mud Run, it's a lot of dirt that'll do a body good. Now in its fourth year at the Del Mar Fairgrounds, the course is changing, but the massive amounts of mud will remain. Participants will receive a finisher's t-shirt, a headband, a beer and more sponsor hookups. Brace yourself for the outrageous obstacles, and of course, the awesome after party. $65-$75 for individuals and unlimited teams. delmarmudrun.com
Rugged Maniac Obstacle Race at Lake Elsinore Motorsports Park – October 5
Rugged Maniac might be a bold name, but don't let that intimidate you. This race was meant for anyone who lives for a little competition. This year, the 5K is taking place at Lake Elsinore Motorsports Park with obstacles ranging from crawling tunnels to a cargo climb, a rope ascent, a tire jungle and more. The after party will treat all the maniacs to live bands, food and beer. $73-$78. ruggedmaniac.com
The Color Run at Qualcomm Stadium – October 12
If your runs have been a bit lackluster, shake it up with some color. In this race, participants start by wearing white as a multitude of shades get blasted throughout the course. You'll leave as a vibrant mess of yellow, green, blue, pink and purple. The Color Run is an untimed 5K, so it's really just about having the most fun. $40-$45. thecolorrun.com
Great Urban Race at various locations – November 2
Think you know San Diego inside and out? The Great Urban Race will put you to the test, "Amazing Race" style. Teams are sent throughout the city to solve a series of clues, tackle challenges and race each other for cash prizes. You'll need to be prepared to take on everything from brain teasers to physical feats. $55-$65. greaturbanrace.com
Electric Run at Del Mar Fairgrounds – November 9
Running never looked so bright. This glow-in-the-dark 5K will literally light up the night on the illuminated course, pumped up with dance music and pulsating lights. Participants are encouraged to join in the party by bringing their own glow sticks and electric accessories. $50-$70. electricrun.com


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Posted by Marty on 1/13/2011, 11:21 pm, in reply to "Re: Phil Brown"
I think Phil Brown is the best of the current crop of candidates that we could have got. It's not as if Jose Mourinho or Arsene Wenger expressed an interest. Even the championship managers that are out of work at present, not many would find a club that are rock bottom very appealing.
I think Phil Brown achieved a lot with Hull and even when he got promoted to the Premier League, he didn't spent ridiculously. It seems he has already six new signings in mind and I hope a decent striker is one of them.
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Alabama's 2015 class at No. 2
Published: Monday, February 24, 2014 at 10:00 p.m.
Last Modified: Monday, February 24, 2014 at 10:41 p.m.
The University of Alabama currently sits with the No. 2 recruiting class in the country for the class of 2015, tied with LSU. Texas A&M has sole possession of the No. 1 spot. The Aggies have eight commitments, Alabama has seven and LSU has nine. Alabama and LSU finished with the top two classes in the country in 2014 while Texas A&M finished No. 6. Alabama has put together a great class early in the process, even though the Tide lost a commitment from five-star quarterback Ricky Town who committed to USC.
The Alabama coaching staff has recruited the state of Georgia very well with three commitments. Dallas Warmack, four-star offensive guard from Mays High School in Atlanta, and Jonathan Ledbetter, Rivals100 defensive end from Tucker High School in Atlanta, are recruited by coach Lance Thompson, who takes the area since the departure of former defensive line coach, Chris Rumph. Thompson is very familiar with Georgia since he spent 11 seasons at Georgia Tech. He also recruited the Atlanta area when he was at Alabama in 2008 and 2009. He recruited former Alabama All-American and first round draft pick Chance Warmack, the older brother of the Tide commitment. Mekhi Brown, Rivals100 defensive end and Alabama commitment from Carver High School in Columbus, Ga., is recruited by defensive coordinator Kirby Smart.
The Alabama coaches have several uncommitted targets they will pursue heavily until next February. They also have to continue recruiting the verbal pledges already listed in the class. Ledbetter and Warmack took unofficial visits this past weekend to Auburn. Mekhi Brown revealed four schools of interest outside of Alabama, and plans to take additional visits.
Ledbetter's teammate, Elijah Sullivan, who is a three-star linebacker, committed to Auburn on Saturday. Sullivan will work on the Alabama commitment the next several months to join him.
Warmack is possibly a little tougher to flip. He has been an Alabama fan for several years. Other coaching staffs in the country will talk of the offensive line class Alabama put together in 2014. It's one of the best in a long while with the Tide signing six linemen including the No. 1 high school (Cameron Robinson) and No. 1 junior college lineman (Dominick Jackson).
Brown hasn't taken any trips yet, but he plans to keep a busy schedule in the spring and summer taking a closer look at all options.
"My commitment to Alabama is still solid," he said. "I am 100-percent. I am talking to Alabama pretty steady. I am talking to Coach Smart at least once a week. He is just checking on me. I am definitely still taking visits though. Everyone in my top five has a shot. I am real solid with Alabama. I am just weighing my options. My list can change, but outside of Alabama I am considering Georgia, USC, Stanford and Florida State."
TideSports.com has the in-depth interview.
TideSports.com also has a tremendous amount of content since the Rivals Camp Series, presented by Under Armour, kicked off in New Orleans this past weekend. One of Alabama's commitments participated, and TideSports.com has video highlights and interview of the other schools coming after him.
Andrew Bone is the senior recruiting analyst of TideSports.com. Follow on Twitter @AndrewJBone.
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