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Flector Patch Side Effects
Generic Name: diclofenac topical
Note: This page contains information about the side effects of diclofenac topical. Some of the dosage forms included on this document may not apply to the brand name Flector Patch.
In Summary
Common side effects of Flector Patch include: increased liver enzymes. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to diclofenac topical: topical application cream, topical application gel/jelly, topical application patch extended release, topical application solution
In addition to its needed effects, some unwanted effects may be caused by diclofenac topical (the active ingredient contained in Flector Patch). In the event that any of these side effects do occur, they may require medical attention.
Severity: Major
You should check with your doctor immediately if any of these side effects occur when taking diclofenac topical:More common:
- Application site reactions, including skin rash, pain, tingling, or burning sensation
- flu-like syndrome (body ache, headache, fever, with or without chills)
- itching skin
- Blood in the urine
- cough
- dry, itching, or burning eyes
- eye pain
- headaches, including migraines
- increased sensitivity of the skin
- nasal congestion
- pain or tenderness around the eyes and cheekbones
- redness of the skin
- redness or swelling of the eyes
- skin rash other than at the application site
- sore throat
- tightness in the chest
- troubled breathing
- ulcers or sores on the skin, other than at the application site
Severity: Minor
Some of the side effects that can occur with diclofenac topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common:
- Burning skin
- dry skin
- scaly skin
- thickened skin
- tingling skin
- Acne
- back pain
- belching
- bleeding skin
- chest pain
- diarrhea
- heartburn
- indigestion
- joint pain
- lack or loss of strength
- loss or thinning of the hair
- muscle pain
- neck pain
- runny nose
- stomach upset or pain
For Healthcare Professionals
Applies to diclofenac topical: topical cream, topical film extended release, topical gel, topical solution
Local application site reactions have been reported in 75% to 86% of patients and have included rash (35% to 36%), pruritus (31% to 52%), dry skin (25% to 27%), contact dermatitis (19% to 33%), pain (15% to 26%), paresthesia (8% to 20%), exfoliation (6% to 24%), vesiculobullous rash (4%), edema (3% to 4%), hyperesthesia (3%), photosensitivity reaction (3%), acne (1%), alopecia (1% to 2%), erythema (less than 1%), irritation (less than 1%), and papules (less than 1%).
The gel vehicle has also been associated with a high incidence of application site reactions (71% to 86%), including pruritus (45% to 59%), pain (22% to 30%), rash (17% to 20%), dry skin (12% to 17%), exfoliation (4% to 13%), and paresthesia (4% to 20%). Other local reactions have included skin carcinoma, hypertonia, lacrimation disorder, maculopapular rash, purpuric rash, skin hypertrophy, and vasodilation in less than 1% of patients.[Ref]
Dermatologic side effects have included pruritus (4%), rash (2% to 4%), dry skin (3%), contact dermatitis (2%), pain (1% to 2%), skin carcinoma (2%), and skin ulcer (1% to 2%). Other dermatologic side effects have included skin hypertrophy, paresthesia, seborrhea, urticaria in less than 1% of patients, and skin discoloration. The gel vehicle has been associated with acne (1% to 2%), herpes simplex (2%), maculopapular rash (2%), and skin nodule (2%).[Ref]
Cardiovascular side effects have included hypertension (1% to 2%), migraine (1%), and palpitation. The gel vehicle has been associated with phlebitis (2%).[Ref]
Endocrine side effects have included hyperglycemia (greater than 1%).[Ref]
Gastrointestinal side effects have included dyspepsia (2% to 3%), diarrhea (2%), abdominal pain (1% to 2%), dry mouth, gastroenteritis, mouth ulceration, nausea, rectal hemorrhage, and ulcerative stomatitis. The gel vehicle has been associated with constipation (2%).[Ref]
Genitourinary side effects have included hematuria (2%).[Ref]
Hepatic side effects have included elevations in serum transaminases in up to 15% of patients as well as rare cases of hepatitis, jaundice, and fatal fulminant hepatitis. Liver injury is most likely to occur in older females in the first 6 months of use.[Ref]
Immunologic side effects have included infection and flu syndrome (greater than 1%).[Ref]
Metabolic side effects have included increased creatine phosphokinase (4%), increased SGOT (3%), increased SGPT (2%), increased creatinine (2%), hypercholesterolemia (1%), hyperglycemia (1%), and creatinine increased. The gel vehicle has been associated with edema (2%).[Ref]
Musculoskeletal side effects have included myalgia (2 to 3%), arthralgia (2%), arthrosis (2%), and leg cramps.[Ref]
Nervous system
Nervous system side effects have included headache (7%), hypokinesia (2%), depression, dizziness, drowsiness, lethargy, paresthesia, and paresthesia at application site. The gel vehicle has been associated with dizziness (4%) and anxiety (1% to 2%).[Ref]
Ocular side effects have included conjunctivitis (2 to 4%) eye pain (2%), blurred or abnormal vision, cataract, and eye disorder.[Ref]
Respiratory side effects have included asthma, dyspnea, pharyngitis, pneumonia, rhinitis, and sinusitis in 2% of patients.[Ref]
Renal side effects have included increased creatinine (2%).[Ref]
Other side effects have included flu syndrome (1 to 10%), accidental injury (4%), infection (4%), back pain (2 to 4%), asthenia (2%), neck pain (2%), pain (2%), chest pain (1 to 2%), ear pain, and taste perversion.[Ref]
1. "Product Information. Solaraze (diclofenac topical)" SkyePharma, San Diego, CA.
Not all side effects for Flector Patch may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
More about Flector Patch (diclofenac topical)
Consumer resources
- Other brands: Voltaren Gel, Pennsaid, Solaraze
Professional resources
Related treatment guides
Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.


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BBOX Radio, a Brooklyn-based, freeform Internet radio station launched its inaugural fundraising operation today through Kickstarter, an Internet funding platform for creative entrepreneurs. BBOX broadcasts live out of a recycled shipping container at the new Dekalb Market. Read on to get in the know on all things BBOX.
BBOX got its start in Urban Space's "Not Just a Container" competition this past spring, which asked entrants to develop the most creative and innovative use for a shipping container at the Dekalb Market. The creative team that authored the winning BBOX Radio proposal included a museum exhibit designer, graphic artists, and a web engineer, among others. With support from the Brooklyn incubator, 3rd Ward, and countless volunteers and supporters, the BBOX team assembled its bare-bones studio and now broadcasts live to the Dekalb Market.
The aim of the thirty-day-campaign is to raise $15,000, which will help the volunteer-run startup move its operations online and become a freeform Internet radio station that serves Brooklyn and New York City, and broadcasts to the world online at bboxradio.com. BBOX will also be a vibrant cultural hub in the Downtown Brooklyn area. The station boasts a curated gallery and outdoor and tented event space that can accommodate hundreds of people.
The inspiration for the station is the iconic boombox of the 1980s, which, in the group's own words, had the ability to spark "an instant block party" by uniting individuals in the shared public spaces of New York City sidewalks and street curbs. In keeping with that inspiration, BBOX plans to operate as much as a physical destination as it will an online hub. The station will host its own music concerts, art exhibitions and parties out of the salvaged shipping container it now occupies in Dekalb Market.
The startup is developing a wide range of locally sourced, original content including:
- Africa21: A show featuring the full spectrum of 21st century music from the African continent.
- The ZRO Hour: The long-running underground and classic hip-hop podcast from DJ Edaye, who is taking his show to BBOX Radio.
- The Many Shades of Green: An interview-based show that delves into topics of urban sustainability in Brooklyn and beyond.
- Crosswave: A radio dance party presenting 80s, New Wave, Indie and Synthpop sounds.
- Filmwax Radio: A weekly radio component to the Brooklyn-based Filmwax Film Series.
BBOX will also feature programs developed with community partners such as PenTales, a global storytelling network; and Carter Magazine, an organization that provides training and mentorship to Brooklyn high school students interested in journalism.
Funds from the Kickstarter campaign will cover online fees and music royalties, and provide the station with studio and gallery supplies, field recording equipment, and equipment for live events. Additional information about the station and its fundraising efforts can be found on the Kickstarter website.
BBOX will also present an end of Kickstarter concert open to the Brooklyn community on Sunday, October 16th. More information on this concert featuring a broad spectrum of music and local acts will be available in the coming days.
About BBOX:
BBOX Radio is a freeform community radio station and venue in Downtown Brooklyn. Located in Dekalb Market, the station operates out of a recycled shipping container, and provides a forum to celebrate community, foster creativity, and explore the vibrant mix of cultures that is Brooklyn.

subset: commoncrawl


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Seymour Lake Park
Oxford, Michigan 1 course · 18 holes Driving directions
Course reviews
Most votes | Newest first | Oldest first
+0 votes Jeff McGuire › June 29, 2011
+0 votes Taylor Goik -Dirty Mitten Disc Golf- › October 7, 2011
+0 votes Steve Brown › October 9, 2011
I would give it a B if the bridge was up. Could only play 14 holes.
+1 votes Steven Welch › February 19, 2012
Bridge is good to go now. Lots of brush cleared.
+1 votes Brent Mitchell › May 19, 2013
+1 votes American Disc Company › February 24, 2012
More improvements to come...
+0 votes Jeff Bauman › February 26, 2012
+0 votes Jeff "Heyman" Schropp › March 5, 2012
Nice course. Good length. Combination of forehand & backhand holes. A brand new walkway has been built to get from #14 to #15, so you don't have to use the Bog Bridge! Lots of blind shots, but once you've played the course, you know where to go.
+0 votes nicholas eastman › March 15, 2012
-2 votes Luke Fouracre › August 2, 2013
I pissed my pants at Seymour on hole 14
+2 votes Lawrence Leonardi essentialdiscs.com › April 23, 2012
This is a Beautiful course! Great mix of shots, Playable for all skill levels and easy to navigate. If you are going to be in the area this is a MUST PLAY!
+1 votes Jim B › May 7, 2012
Played the course for the first time. I like it. Had a hard time finding 15. Overall its a nice course. Could use some signs on each hole.
+0 votes Adam Mitchell › June 10, 2012
+4 votes Jeffrey Sutherland › June 11, 2012
Course is always nice. Need more people to pick up trash. STOP PAINTING AND WRITING ON EVERYTHING. Disc golf does NOT need to be a graffiti sport.
+0 votes doug granby › June 16, 2012
+1 votes Paul DISC-OR-DIE Holstein › July 4, 2012
As of 07/04/2012 this is a B+ course and suitable for tournaments. It's hard to get past the problems that plagued this course over the past few years, but there are now 18 holes and the bridge is fixed. They have also cleaned the course up, added landscaping, and it's very nice. Hole one still borders on a parking lot that is a recipe for disaster and the pond at hole one rises so far that it interferes with several holes. Other that that, this course is really coming around, Kudos to everyone that helped.
+0 votes Alex Wigand › August 1, 2012
Nice course layout. keep your eye out for the bricks in the ground marking next tee, there are few posts.
+0 votes Andrew Hughes › August 11, 2012
+0 votes Brian Goodmurphy › September 13, 2012
+1 votes Bob Cox › November 11, 2012
+1 votes Andy Smith › March 4, 2013
This is a good course it just needs some fine tuning to be great. I have liked some of the new improvements and I've seen it come along way in some respects.You get a little of everything and some holes are challenging some could be better. Over all a decent place to play. Just not a must.
+1 votes Tony Maccarino › March 13, 2013
Nice course, good mix of open windy holes with water, and some woodsy holes. Good distance on most holes. Pretty fun course, lack of signs can get confusing but there are signs in the ground pointing to next tee. Some holes its tough to tell which way it goes but follows a decent format. Hole 11 I missed and was throwing deep, hole is short to left.
+1 votes JT Reynolds › April 19, 2013
+1 votes Mike A › April 12, 2013
+0 votes Jake Neighbors › May 12, 2013
Liked the design! The holes were fun and varied nicely It took some experience to do well but overall it was good and easy to keep track of your disc. It was missing distances and hole descriptions. With a little work it could one of the best around.
+0 votes Josh Drouillard › June 4, 2013
The fairways were cut from Sunday. Also only had to pick up a few pieces of garbage. Is this course finally turning around?
+1 votes Miles Lawrence › June 17, 2013
The bridge is fixed and is now a solid land bridge through the swamp between 14 and 15 thanks to Tom for the initial spark. The pond issue is being controlled (for now, and looking good) thanks to Ron Davis and the township parks & recs. All 18 baskets now have 24 chains instead of 18 thanks to the Murder Mitten DGC. With more fundraising events from the MMDGC in the future this course is well on its way to being a top notch course. This course is looking better then i have ever seen it before. A now but A+ within a year.
+2 votes Brandon Tolliver › June 17, 2013
Overall a great experience. Good mixture of open baskets and wooded. Played the pond safe, no big deal. Finding the next tee wasn't a task but knowing where the basket was located seemed hard, we sent a spotter on a few. Our club plays everything par 3, birdied a couple baskets. Glad we added this course to our Saturday tour.
+1 votes donny stevens › June 29, 2013
nice place
+1 votes Seth Krueger › July 9, 2013
+1 votes Eric Walker › August 4, 2013
+1 votes Anthony Litts › September 29, 2013
Nice clean course.
+1 votes Evan David › October 11, 2013
+2 votes Aaron Torres › October 13, 2013
The course has had some major improvements over this and previous summers. Foliage has been cleaned up on every fairway, shot lines have been opened up to a more familiar look for those who have played the course over the years. There are waste baskets now at every tee pad to help control the litter, STOP THROWING BOTTLES IN THE ROUGH!! we have trash cans now that are freshly painted. The next tee signs have all been pulled, repainted, clear coated and moved to a location to make it easier to na ...
continue reading ›
continue reading ›
The course has had some major improvements over this and previous summers. Foliage has been cleaned up on every fairway, shot lines have been opened up to a more familiar look for those who have played the course over the years. There are waste baskets now at every tee pad to help control the litter, STOP THROWING BOTTLES IN THE ROUGH!! we have trash cans now that are freshly painted. The next tee signs have all been pulled, repainted, clear coated and moved to a location to make it easier to navigate the course when you come in on the pin on each hole. As Miles said, every basket is now double chained as well, with a beautiful land bridge now between #14 and #15. Course still needs to have tee signs with distances for every hole and an announcement board with course layout on it, both of those are currently in the works to be installed end of fall, beginning of spring. Overall course plays great! excellent variety of shot making and challenges. Give it an A to and A-
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+1 votes David Lewis › March 29, 2014
+1 votes Worm Bothwell › April 7, 2014
Best course around
+2 votes Mike Dodd › April 19, 2014
Need tee markers!!
+0 votes Evan Little › August 11, 2014
+0 votes Christopher Bence › August 16, 2014
Pretty good course!
-2 votes terry m › August 21, 2014
the first three holes very confusing, there is no hole lay out so if your a 1st timer your lost and golfing blind.
+1 votes Jeff Hulet › September 24, 2015
+0 votes Dan Brock › October 11, 2014
+0 votes Joe McConnaughhay › October 17, 2014
+0 votes richard bell › October 6, 2015
One of the best free ones around by far. Well taken care of. Nice cut fairways with some blind tee shots sprinkled in. Garbage cans and benches at almost every tee. No restrooms. Hardly ever see garbage on this course.
+0 votes James Kahn › April 16, 2015
+1 votes Kevin Boynton › April 18, 2015
Just a beautiful golf course. Absolutely loved it! No problems navigating the course, I especially liked the directional signs to the next tee at each basket. Grooming is immaculate, great baskets, nice tee pads, everything is first rate. Outstanding design by the architect. He knocked it out of the park. I will be back a lot. It is worth the trip from Lansing to play Seymour Lake.
+1 votes Jim Hodges › May 16, 2015
+2 votes Matt London › June 5, 2015
Well maintained and close to home! Nice mix of open and wooded holes. Nice basket placement! My new home course!
+1 votes Nathan Brubaker › July 13, 2015
+1 votes Vinnie G › July 14, 2015
+2 votes Zak L › August 11, 2015
+0 votes Bill Murray › August 27, 2015
This course eats discs for breakfast
+2 votes Ron Jacobs › December 12, 2015
This course is awesome. Good mix short long wooded open, bathrooms, practice basket, tee signs and markers. FREE
+1 votes matt w › November 14, 2015
+1 votes Josh Marshall › January 30, 2016
+2 votes David Tomlinson › February 22, 2016
This a great course.
+1 votes Henry Theodoroff › March 19, 2016
Super nice course, threw about every shot I had in my bag. Great variety of short, long, BH or FH. Only con is that there are no markers on the tee sign to show where the basket is from the tee.
+1 votes Dave Heileman › April 19, 2016
+1 votes Chris Trumbull › May 2, 2016
+2 votes Brendan Livingston › May 10, 2016
I really can't see a way to improve this course. It has it all, just maybe getting dated now that it's 15 years old. For first time players I recommend either playing a practice round, walking the course or playing with someone with knows the basket locations well. I would say almost half the tee shots are blind to the basket, which makes for a frustrating first round. This is quite a park and paired with the 20 min drive to Addison Oaks, it makes for a shining area for the disc golf world to visit.
+1 votes Russell Wixom › May 30, 2016
+1 votes Skyler Stoker › June 8, 2016
Decent variety and some elevation change. Overall a fun course to play just wish it was a little more secluded. Errant shots can hit some dangerous areas such as playgrounds and baseball fields.
+0 votes Tom Wagner › August 11, 2016
+0 votes Jordan Bailey › July 21, 2016
Out of Bounds areas are very thick and overgrown, very easy to lose a disc if your shot hooks left or right into the shrubbery.


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Home / News
and Information /
BPC receives $200,000 grant to upgrade McArthur Clinic
By Kelley M. Arnold
Director of News and Public Information
MOUNT VERNON—The Georgia Baptist Health Care Ministry Foundation (GBHCMF) recently awarded a $200,000 grant to Brewton-Parker College for the purpose of updating its on-campus infirmary, the McArthur Clinic – the primary health care provider to the college's students and employees in Mount Vernon.
The grant was formally presented to the college Feb. 7 at a Grantees' luncheon at the Georgia Baptist Missions & Ministry Center in Atlanta.
The grant will be used to fund capital improvements to the clinic, including new carpet, new equipment, added security and repairs to the building, reported Doug Baird, BPC vice president for college advancement.
"The Georgia Baptist Healthcare Ministry Foundation grant will assist Brewton-Parker College to fulfill its mission by (continuing to provide) a caring, Christian health center for students, faculty, staff and some community members, while bringing fine professional healthcare providers to our campus," said Dr. David R. Smith, BPC president. "The McArthur Clinic is a place where members of this community can find physical remedies and be exposed to spiritual solace through the provision of evangelistic materials placed there by the College. We are very grateful for this needed gift that will considerably improve service to our constituents."
According to Baird, "the building housing the McArthur Clinic was donated over 20 years ago to the college to serve the health and spiritual needs of the community. Ten years ago, medical equipment was donated by (then-BPC trustee and retiring physician) Dr. Leonard Durrence of Blackshear to further those pursuits. This clinic is the only medical opportunity for Brewton-Parker faculty, staff, families, and in many cases, the community, for many miles. Without this facility located on campus, the health needs of our community would go untended."
The McArthur Clinic is staffed by local doctors Nancy Elwood and Joseph Foust.
According to its website, the Georgia Baptist Health Care Ministry Foundation is a supporting organization that primarily provides financial support to the health care ministry of the Georgia Baptist Convention within the state of Georgia. Secondarily, the Ministry Foundation will assist Georgia communities and others it serves with worthwhile health care related programs.
Brewton-Parker College is the only accredited four-year Christian college in south Georgia. It is affiliated with the Georgia Baptist Convention.


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In Notizie degli Scavi, prior to January 1897, this house may be described as being in Insula 12 of Reg. VI, afterwards it was changed to Insula 15 of Reg. VI.
In Notizie degli Scavi, January 1897, plan on p.14, this house was numbered as VI.15.3.
In Notizie degli Scavi, May 1897, p.198, it was renumbered as VI.15.2. See Note on Region VI, Insula 15 plan for information.
VI.15.2 Pompeii. December 2005. Entrance doorway.
According to Della Corte, found on the right side of the entrance doorway, between VI.15.2 and 3, was the graffito –
Appuleia cum Mustio vicino f(acit) et Narcissus vos rogat [CIL IV 3527]
See Della Corte, M., 1965. Case ed Abitanti di Pompei. Napoli: Fausto Fiorentino. (p.66 and note 3)
According to Epigraphik-Datenbank Clauss/Slaby (See www.manfredclauss.de) it read -
IIvir(um) i(ure) d(icundo) o(ro) v(os) f(aciatis) Appuleia
cum Mustio vicino f(acit)
et Narcissus vos roga[t] [CIL IV 3527]
VI.15.2 Pompeii. September 2004.
Entrance corridor, looking west from entrance across atrium, through tablinum to garden at rear.


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LANSING - Sex Offenders will have to pay a fee to maintain the sex offender registry in Michigan. On Tuesday Governor Snyder signed into a law a measure that charges registered sex offenders $50 a year for as long as they are required to be on the sex offender registry. The law was sponsored by Senator Rick Jones of Grand Ledge.
"This law will help reduce taxpayer costs to maintain Michigan's sex offender registry," Gov. Rick Snyder said in a statement sent to the media. "By requiring registered sex offenders to pay an annual fee to fund the registry website, law enforcement will be able to direct more of its resources to public safety."
Previously, registered sex offenders only had to pay a one-time fee, which only provided enough revenue to cover about 10 percent of the cost to maintain the state's sex offender registry, according to the Governor's office.


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American English: /ˈbɛn(t)ʃmɑrk/ British English: /ˈbɛn(t)ʃmɑːk/
Translation of benchmark in Spanish:
- 1 (surveyor's mark)Example sentences
- A benchmark is a survey mark made on a monument having a known location and elevation, serving as a reference point for surveying.
- The benchmark is a standard survey ordinance mark, a horizontal line about 500 millimetres long, and with a broad arrow just above it, under a small cliff on the northern face of the island.
- 2 (criterion)Example sentences
- The bidders for the women's prison all tendered below what the Government set as the benchmark for minimum standards - so the corporations were asked to up their bids.
- The baseline then serves as a benchmark for comparing the financial implications of alternative plans.
- The New Zealand Qualifications Authority, the agency that is meant to set the benchmark for standards in education, is saying that it is going to provide credits for picking up rubbish.
- 3 (Computing)also: benchmark testExample sentences
- Our hard drives and optical drives are different between our new and old tests, but those won't affect 3D graphics performance benchmarks.
- The testing continued with the usual motherboard performance simulations and benchmarks.
- We've used the below noted system configuration for all benchmarks with all video cards.
Definition of benchmark in:
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Grammar and usage help for Spanish:
= trending


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Thousands of dollars worth of merchandise will be on display during the LIVE UNITED Kick-Off Auction, which will raise funds for the United Way of Randolph County's 27 partnering agencies.
One of the most anticipated items in the auction will be the United Way quilt, a project which includes many members of the community. This year's quilt was unveiled Tuesday at Citizens Bank of West Virginia in Elkins, where it will remain on display until the day of the auction.
Sue Pifer, owner of the Elkins Sewing Center, said the quilt took nearly a year to complete.
Article Photos
The Inter-Mountain photo by Beth Christian Broschart
The United Way of Randolph County showcases a quilt that will be auctioned off during the LIVE UNITED Kick-Off Auction Aug. 24. The quilt, crafted by several area quilters, will be on display at Citizens Bank of West Virginia in Elkins until the day before the auction. Pictured with the quilt are, from left, Sue Pifer, owner of Elkins Sewing Center; JoBeth Agnor, United Way of Randolph County's executive director; and Kathy Leombruno, board member of the United Way of Randolph County.
"In January, we put together the quilt block kits containing material for the quilt, that people come and purchase," Pifer said. "Quilters throughout the community craft their blocks, that they return to the store in March.
"The completed blocks are put on display and those visiting the store are encouraged to vote for their favorite block. A small gift is given to the quilter of the favorite block."
Pifer said a member of her staff, Denise Kramer, arranges the completed blocks and pieces the quilt. This year, the quilt has been named "Hope Blooms," and will fit a full- or queen-size bed.
"Once the quilt is pieced together, Patsy Turner uses her long-arm quilter to complete the quilt," Pifer said. "When the quilt if finished, we put it on display for everyone to see before the auction."
The LIVE UNITED Kick-Off Auction is slated to begin at 10 a.m. Aug. 24 at the First United Methodist Church in Elkins. The doors open at 9 a.m., and items on the buy-and-go tables will be for sale beginning at 9 a.m.
The auction will begin at 10 a.m. and feature many baskets, tickets, merchandise, gift certificates and hand-made items for sale.
Proceeds from the auction benefit 27 local organizations, including the American Red Cross, Boy Scouts of America, Catholic Charities West Virginia, Energy Express (WVU Extension Office), Foster Grandparent Program, Girl Scouts Black Diamond Council, Helping Hand Clearinghouse, Elkins/Randolph County Library, Helvetia Library, Pioneer Library, Tygart Valley Library, Valley Head Library, Literacy Volunteers of West Virginia, Meals on Wheels, North Central Community Action (Homeless Shelter), Randolph County Cancer Support Group, Randolph County Children's Advocacy Center, Randolph County Domestic Training & Referral, Randolph County Emergency Squad, Randolph County Family Resource Network, Randolph County Humane Society, Randolph County Senior Center, Randolph County Sheltered Workshop (Seneca Designs), Senior Companion Program, Women's Aid In Crisis, Elkins-Randolph County YMCA and Youth Health Services.
The United Way of Randolph County is still accepting donations for the LIVE UNITED Kick-Off Auction. Items can be taken to the office in Elkins, located at 309 Henry Ave. in Elkins. Additional information is available by calling 304-636-0516 or emailing email@example.com.


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Links are a very big deal in Dollywood.
|<IMG height=300
Links & peppers in a giant skillet at the Sausage Works, Dollywood.
*Calling Dr. Seuss: a drunken Welsh chef visiting a pizza parlor assaulted a roofer by hitting him with a rock in a sock. (He got 15 months.) [Daily Post]
*Here's something wild: Taipei's Mr. Baoz, which of course serves all manner of the steamed, stuffed Chinese buns called baozi–some of which the sourpuss reviewer finds "off-putting" or downright "revolting." Check out this video, though. Ai yi! [Taipei Times]
*If you're like me, you just can't get enough of those Mr. Baoz videos. Check this teaser for a new Malaysian location. and this surpassingly strange Japanese production.
*Dunkin' Donuts pulled its ads featuring TV chef Rachael Ray after nut-job critics claimed her fringed paisley scarf resembled a kaffiyeh, (thus supporting terrorism). And wan't that a bogeyman lurking beneath those cherry trees? [Michelle Malkin]
*The roundly disliked Lisa Fernandes on Top Chef gets her own special satanic animation from comedian Max Silvestri. Nice GIF! [maxsilvestri.com] — via Gawker
*Spike Mendelsohn, Top Chef's most recent bootee, gets debriefed. Tidbits: he's buds with Marcel; he and Lisa (gulp) are now working together at Mai House in NYC. [Yumsugar.com]
*Last but not least: world's hungriest kittens await the dinner hour in this entertaining video. [Neatorama]


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The Construction & Surety Law Newsletter features decisions and statutes relating to the practice of torts, insurance and compensation law. Edited by Henry Melchor, Esq., the Construction & Surety Law Newsletter is published by the Torts, Insurance & Compensation Law Section and distributed to Section Members free of charge.
The Newsletter is published as a benefit for members of the Torts, Insurance & Compensation Law Section and is copyrighted by the New York State Bar Association. The copying, reselling, duplication, transferring, reproducing, reusing, retaining or reprinting of this publication is strictly prohibited without permission. © New York State Bar Association.All rights reserved. ISSN 1530-3977 (print) ISSN 1933-8449 (online)
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I have a 2000 WJ 4.0 L. After having Death Wobble I have overhauled a lot in my front suspension, including new tie rods also put in new rotors and brakes. Now I am going to put in a steering stabilizer. I have read many forums on opinions. I currently have one from napa - $41 - sc2962.
I was thinking about taking it back and purchasing a moog, rancho, or monroe from Advance Auto Parts. Thoughts?
Also, this is the first time I have replaced the SS. I read on some forums that they had to drill. Am I going to have to drill to change this?


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DURHAM — Nicole Grote had four goals and seven points as the University of New Hampshire women's lacrosse team beat Binghamton, 18-5, on Saturday at Memorial Field.
The Wildcats improved to 7-7 overall and 2-1 in America East. UNH is 13-0 all-time against Binghamton, which fell to 6-7 (0-3).
Laura Puccia added three goals for UNH and boosted her career total to 100. She also had an assist. Kayleigh Hinkle contributed two goals and five assists, giving her 101 career points.
Marissa Gurello (three goals), Becca Graves (two goals) and Laura McHoul (one goal, one assist) also finished with multiple points. Taylor Hurwitz was credited with six saves.
Renee Kiviat led the Bearcats with three goals.
UNH scored the first nine goals of the game and led 11-2 at halftime.
Location, ST | website.com


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Devils Q&A with Zach Parise
Friday, 08.20.2010 / 10:20 AM ET / Features
By Eric Marin
|Zach Parise led the Devils last season with 82 points (38g, 44a).
"It was unbelievable," said Parise, who was joined by a group that included his brother Jordan, Islanders forward Kyle Okposo, and Sabres forward Drew Stafford. "It was great and that new stadium is sick. Really cool, we had a good time."
Back from the ballpark, Parise took the time to answer the fans for our second installment of Devils Q&A. Questions ranged from his offseason training regimen to the impact that his father – former NHLer J.P. Parise – has had on his hockey career.
With all the new additions that management has made this season, are you more excited for this season, and are expectations high?
Sparta, N.J.
ZP: I think everybody's expectations are high with some of the guys we've got. We improved our team and everybody's looking forward to coming back and starting again. That's quite a few postseasons in a row that we've been pretty disappointing, so we're all looking forward, and we're excited to get back and start playing again.
How will the team adjust and mesh for the upcoming season?
Williamstown, N.J.
ZP: I guess, like you do every season, you have guys that you're familiar with and new guys that you've inserted into different roles. You have Jason Arnott and the new defensemen, Henrik Tallinder and Anton Volchenkov, but it's just like every season, you have to mesh. You don't have a choice if you want to do well. But we've never really had a problem with meshing as a team. We've always had good guys off the ice, so that's never been a problem.
What type of workouts or training do you do during the summer to prepare for the upcoming season?
Toms River, N.J.
ZP: I got a new trainer this year and we do a lot of different things. We lift weights Monday, Wednesday, Friday, and Tuesday, Thursday we do all speed, agility and conditioning. This year it's been a lot different because I've done more conditioning than I've ever done, so it's a different type of workout. But it's been fun, it's been really good and I'm kind of anxious to see how it'll translate over to the ice.
|Parise (r.) and Jamie Langenbrunner (15) celebrate the tying goal.
Ancaster, Ontario
ZP: It was just one of those things that you can't believe happened. Your instincts take over and you forget, almost like you blackout, I guess. I've seen it on film and there's certain things you remember when you're playing, but after it went in, I think I was just too excited and too happy that I don't remember what exactly was going through my mind. Certainly excited that we had a chance to win a gold medal after that goal.
Who do you admire in today's NHL?
Long Branch, N.J.
ZP: Sidney Crosby's tough not to admire. I think he's a great player, and he's consistent. He's always on top of the scoring list, and he's always getting the tightest checking. There's not a lot of room for him out there, but he always seems to end up on the scoresheet making plays and helping his team win.
In what ways has your dad's NHL success influenced and shaped you as a hockey player?
Livingston, N.J.
ZP: You learn from him what it takes to get there, and how hard it is not only to get there, but stay there and be productive. When you have someone that did it and went through it all, he's able to tell you what to expect and help you through when times get times get tough. Having been there, he's able to make sure you don't get too worked up. He's able to teach you things that you can't learn everywhere. My dad always said to me he knows when I know I've played a bad game, and he knows that I don't want to hear about playing a bad game because I know it. I think sometimes you run across where parents kind of give it to their kids if they don't play very well. I don't think that's a productive way to do it. It burns the kids out and they don't enjoy it anymore.
If you could play hockey with or against any retired hockey player, who would it be and why?
Syosset, N.Y.
ZP: I'd like to play with or against my dad; I think that'd be pretty fun. I love the way Joe Sakic played. From what I hear he was an unbelievable leader and just a great player and a great person. I think he would be my choice.
How did your time in Albany (AHL) help your game in the NHL?
Schenectady, N.Y.
ZP: I would say you learn the tough schedule, the 80 games, and the competition's obviously better than at the college level. When I was there [2004-05] most teams had three, four NHL regulars because of the lockout so it made the league a little bit better.
What is your favorite memory of being in Grand Forks and playing at the University of North Dakota?
Grand Forks, N.D.
ZP: Playing in that building [Ralph Engelstad Arena] is pretty awesome. It's a great building to play in. Number one would be when we won the [2004 WCHA] championship at home, so it was pretty cool skating around with the rink with the MacNaughton Cup when we won it. But then, we ended up playing in Minneapolis at the XCel Center in the Final Five championship and I think there were 21,000 people there when we played against the University of Minnesota. The college atmosphere is crazy. The crowd and everything is so much fun. We ended up losing 5-4, but it was an unbelievable game to play in.
Carteret, N.J.
ZP: It just happens. There's times in games where you don't have time to think, you don't have time to analyze anything. It just happened to work out like that. The pass came kind of behind me, so I had to spin to get it and I figured that [Steve] Mason would be thinking that I was just going to take a quick backhand. I held on to it for a second longer. That's all just reaction and instincts.
Did you think, 'Wow this is gonna be on the highlight reel for sure?'
ZP: All the guys were saying it was. I was pretty excited about it because I don't always get the opportunity to get the pretty goals very often.
How do you have such an explosive backhand shot? Tips? Pointers?
Little Ferry, N.J.
ZP: I just practice it. I would say it's just quick. I'm able to lift it quickly. It probably wouldn't break wet toilet paper but it's quick and it can get up under the crossbar quickly.
What was your favorite team as a kid?
Ajax, Ontario
ZP: The North Stars. I didn't really have a favorite team after they moved. I always loved the North Stars and it was tough to switch. It took me a couple years, but once I got over that, I really liked Colorado.
Favorite North Star?
ZP: Either Mike Modano or Neal Broten [former Devil and 1995 Stanley Cup champion]. Either one of those guys; they were awesome to watch.
What is your favorite TV show?
Short Hills, N.J.
ZP: It was Lost until that ended. They did a good job of making you want to watch it the next week or next episode. It was just entertaining. By the last couple of seasons there were so many questions that you wanted answered that you had to keep watching. It was something you looked forward to watching. The finale was amazing... and confusing. I'm still not sure what happened [laughs], but it was crazy, I thought. I just started watching the first few episodes of Rescue Me and I like that a lot, so I'm going to keep watching that one.
Who is your favorite cartoon character?
Somerset, N.J.
ZP: Randy Marsh from South Park, I think he's hilarious.
|Travis Zajac
ZP: Andy Greene is really funny… I think Travis Zajac is funny, but I think I'm one of the few guys that hears him talk. I'd say those two guys.
What is your favorite food?
ZP: I eat so much pasta it's amazing that I don't get sick of it. But my favorite is probably tacos, chicken tacos. It's amazing, with the ground chicken, sour cream and peppers. It's awesome.
If we put your iPod on shuffle, what would we find ourselves listening to?
Dumont, N.J.
ZP: You'd find everything right now: I've got Pearl Jam, Eminem, George Strait, Tim McGraw, Dierks Bentley, Metallica. I think George Strait is my favorite; I don't think I ever get sick of listening to him. "Troubadour" is great, "Run" is unbelievable.
What is one thing most people don't know about you?
Princeton, N.J.
ZP: Probably that I've bungee jumped before. I was visiting a buddy of mine in Colorado, I don't know how many years ago, I had to be around 12 – I was really young. I'm terrified of heights, but we went bungee jumping. I do not like flying, either.
What drives you to just skate so hard whether you are on the puck or not?
Manalapan, N.J.
ZP: I enjoy doing it. I find that that's the way I need to play and what I need to do to score and be effective on the ice. Different guys have different niches, and I feel that's mine and that's when I'm productive, when I'm skating.
Keep visiting the Devils official site this summer for more Q&A sessions with your favorite players!


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Why You Shouldn't Vote for Libertarian Nominee Gary Johnson
Voters of all political persuasions will find something objectionable in the Libertarian nominee's positions
Voters of all political persuasions will find something objectionable in the Libertarian nominee's positions
19 hours ago
Curt Schilling lost his job as an ESPN analyst earlier this year.
21 hours ago
Departure comes almost two months to the day after Corey Lewandowski was fired
5 days ago
"In Hillary Clinton's America, the system stays rigged against Americans," opens Republican nominee's spot targeting swing states
5 days ago
Trump's new campaign manager, Kellyanne Conway, promises to let Trump be Trump.
6 days ago
Filmmaker claims Republican nominee is self-sabotaging campaign he launched as a negotiating tactic
August 16, 2016
Open letter signed by Republican leaders urges Reince Priebus to abandon Donald Trump financially, put party resources behind down-ticket candidates.
August 16, 2016
Donald Trump toned down his rhetoric on Muslim immigrant ban, NATO support in new speech detailing his foreign policy plan.
August 15, 2016
Campaign 2016 won't just have lasting implications for American politics. It's obliterated what was left of our news media
August 15, 2016
Mitt Romney, Jeb Bush, Ted Cruz and Susan Collins are among the Republicans who have come out against Trump.
August 12, 2016
Stephen Rogata attempted to scale 68-story building in order to meet Republican presidential nominee
August 11, 2016
Hillary Clinton's candidacy can be traced back to the New Deal era.
August 11, 2016
"The co-founder would be crooked Hillary Clinton," Trump tells Florida crowd
August 11, 2016
Hillary Clinton continued to attack Donald Trump over comments the Republican candidate made to Second Amendment supporters.
August 10, 2016
His comments about "Second Amendment people" were the product of a violent campaign and Republican Party
August 10, 2016


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Definition of bippy in English:
Entry from British & World English dictionary
noun (plural bippies)informal
A person's buttocks.
Example sentences
- You bet your sweet bippy they do.
- And if that one doesn't fly, you can bet your bippy they'll find a third.
- You bet your sweet bippy that we dream.
1960s: popularized by the US television programme Rowan & Martin's Laugh-In, where it was used as a nonsense word with an air of innuendo but intentionally vague meaning: of unknown origin.
For editors and proofreaders
Line breaks: bippy
What do you find interesting about this word or phrase?
Comments that don't adhere to our Community Guidelines may be moderated or removed.
= trending


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firstname.lastname@example.com changed:
What |Removed |Added
Status|NEW |RESOLVED
Resolution| |WONTFIX
Summary|Rsync --min-size and --max- |Rsync --min-size and --max-
|size filter too late in the |size filter too late in the
|process. |process.
------- Comment #1 from email@example.com 2008-08-31 12:29 CST -------
Those options just affect what files in the file-list may be transferred. If
they actually excluded files from the file-list, the receiving side would not
be able to correctly handle a --delete option.
You should instead sub-set the directory using an exclude, such as
--exclude='dir/[a-m]*' for one run, and --exclude='dir/[n-z]*' for the other
(or something similar).
Configure bugmail: https://bugzilla.samba.org/userprefs.cgi?tab=email
------- You are receiving this mail because: -------
You are the QA contact for the bug, or are watching the QA contact.
Please use reply-all for most replies to avoid omitting the mailing list.
To unsubscribe or change options: https://lists.samba.org/mailman/listinfo/rsync
Before posting, read: http://www.catb.org/~esr/faqs/smart-questions.html


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Welcome to the KnittingHelp forum! ...Introduce yourself!
View Single Post
Casting On
Join Date: Nov 2004
Posts: 1
Thanks: 0
Thanked 3 Times in 1 Post
Brand Spanking New to Knitting
I don't know what got into me today but driving home from a Georgia Tech football game, I decided it would be a great idea to take up knitting so that I can make scarves in the school color for all my friends. This is of course a fad and I should get over it in a week or two but so far I'm still on course. I went by Michaels and picked out my soft yellow and navy yarns, how to knit kit that came with a book, needles and bunch of things I didn't recognize and stood in the check out lane. I then saw Michaels' offers knitting classes for $15.00 which sounded like a better idea and off went the supplies. After I came home, I remembered I have a memory span of about 15 minutes which means I'll have to take a whole lot of the classes at $15 per session. I then ran a goggle search for 'how to knit video' and here I am! What an awsome site!! The videos are incredible for newbies like me. I have viewed every single video under Basic Techniques and feel like I might be able to tackle knitting after all. In fact, I'm heading out the door to the 24 hour Wal-Mart for my supplies so that I can get started. But before I buy out the store, I wanted to let you (Amy) know how appreciative I am for this website. Regardless of how long this fad may last for me, you have at least helped me make the first step. And who knows - I might just surprise and end up being a marathon runner.
Thanks so much (especially for the videos).
The Following 3 Users Say Thank You to eye595 For This Useful Post:
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AP Biology
Exam Practice
Exam Day 2016
May 09
08:00 AMView AP Exam calendar.
The AP Biology Exam is approximately three hours long and has two sections. Section 1 is Multiple Choice and Grid-in questions and Section 2 is Free Response Questions.. Each section is worth 50% of the final exam grade.
Section 1 lasts 1 hour and 30 minutes and contains 63 multiple choice questions and 6 grid-in questions.
Section 2 lasts 1 hour and 30 minutes (which includes a 10-minute reading period), and contains 8 questions consisting of 2 long free-response questions and 6 short free-response questions.
You can find samples of both the multiple choice (pages 128-163) and free response questions (pages 164-168) in the AP Biology Course and Exam Description, which can be found in the blue, Exam Resources inlay to the right. You can also use the free response questions below as you prepare for the AP Exam.
Free Response Questions and Scoring Guidelines
Free Response Questions and Scoring Guidelines: login
The following resources contain the remaining available Free Response Questions and Scoring Guidelines for the AP Biology Exam. To access the files below, you need to log into your College Board account. If you do not have a College Board account, you can create one by selecting 'Sign In' in the header and following the prompts to Sign-Up.


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William Claxton
This is as much book you can get for € 50,00. American photographer William Claxton travelled across the US in the 1960s and documented the jazz scene of those days. His journey brought him from San Francisco to Boston and from Chicago to New Orleans. Of course, New Orleans. "In the old New Orleans funerals, sad music was played on the way to the cemetery, and happy music was played on the way home." That's the atmosphere you will abstract from this book. No matter how miserable, shitty, painful or unjust the situation is, there's always the music. The books comes with a cd with 23 digitally remastered original recordings from the 1960s.
€ 50.00
552 pages
Hardcover with jacket
Including CD
English, French, German
September 2010
247×345×60 mm
4200 grams
The intellectual property rights to the images of the books belong to their respective authors or publishers. These images are used by MENDO with the sole purpose of promoting the books.


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HUNTSVILLE, Ala. – Authorities are investigating the early morning thefts of three 2013 motorcycles from Rocket Harley-Davidson.
The owner of the store told police someone approached from a cotton field on one side of the store and broke in around 2:45 a.m. July 11. Three motorcycles valued at around $30,000 each were missing from a storage unit when employees arrived.
The investigation is ongoing, according to WAFF.
Posted by Holly Wagner


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When Pharmaceutical Technology first appeared in 1977, the US Food and Drug Administration was a much smaller and less well-known government agency in the Department of Health, Education, and Welfare. Donald Kennedy, a prominent neurophysiologist from Stanford University, was the newly named commissioner. FDA was undergoing visible change as it strove to update the drug provisions in the Food, Drug, and Cosmetic Act. The act had been altered considerably by the 1962 Kefauver–Harris Amendments, which were generated in response to the thalidomide crisis that began in 1956. The amendments required drug manufacturers to submit clinical evidence of both safety and effectiveness before marketing a new medicine.
Eight commissioners have led FDA since then, presiding over a period that has witnessed the emergence of user fees, drug advertising, and drug-safety concerns. All these changes have increased the agency's oversight of drug development and market approval. They also have prompted more congressional attention to FDA and industry activities. Today FDA is struggling to assure the public and policymakers that it has the ability to ensure the quality and efficacy of medicines. It also is striving to modernize its regulatory programs and encourage pharmaceutical innovation, thereby addressing many of the challenges facing the pharmaceutical industry today.
During the 1970s and 1980s, FDA launched many key initiatives, including a retrospective review of over-the-counter (OTC) drugs and an increased collection of adverse drug reports, and reorganized and expanded its Bureau of Drugs (see sidebar, "FDA builds drug oversight infrastructure"). Reports of AIDS in the 1980s spurred demands from patient advocates for faster access to promising therapies, prompting a general rethinking of regulatory attitudes. The thalidomide crisis had fostered a cautious approach at the agency, encouraging staffers to move slowly in reviewing new drug applications. The AIDS epidemic, though, spurred agency officials to adopt a less risk-averse attitude, acknowledging that their job was to facilitate patient access to needed treatment as well as to guard against unsafe products. Other important developments are described below. AIDS-influenced regulation. The first reports of AIDS expanded FDA collaboration with researchers and scientists to approve initial immunoassay tests. Several rule changes in the mid-1980s broadened access to experimental drugs for patients with serious diseases and no alternative treatment options. FDA approved AZT (azido-thymidine), the first drug to treat AIDS, in 1987, as well as treatments for opportunistic infections.
Orphan-drug development. Congress passed the Orphan Drug Act in 1983, launching an innovative program that encourages industry to develop treatments for rare diseases, i.e., conditions affecting fewer than 200,000 people in the United States. The law provides extended market exclusivity for such drugs and medical products and awards grants to support orphan-drug clinical trials. These incentives have led to FDA approval of nearly 300 drugs and biological products under this program.


text:
Public and private foundation support is critical to Dana-Farber's lifesaving mission. It provides seed funding for high-risk/high-reward research, ensures that innovative patient care programs are sustained, and furthers educational outreach efforts throughout Greater Boston and around the world.
If you are interested in learning more about how foundations can make an impact at Dana-Farber and help conquer cancer, please contact Allyson Ahern, Assistant Vice President of Corporate and Foundation Relations, at 617-582-7456 or email firstname.lastname@example.com.
Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215 | Call us toll-free:


text:
JUL 07, 2014 - New York Times
A Must Read - Share
Responding to criticism about how she defended a rape suspect in 1975, Hillary Rodham Clinton said she had asked to be removed from the case, but was not.
Editor's Picks
Hey you have no friends!!! Get to work and start inviting friends to help build your Comunitee. Click Here to invite friends.
© 2011 Comunitee, Inc.


text:
Bill Nye Had a Ball on Whose Line Is It Anyway?
The man loves to dance.By Margaret Lyons
The man loves to dance.By Margaret Lyons
He also suggests that watching paint dry could be interesting, because science.By Greg Cwik
"The YouTubes has more science than Bill Nye the Science Guy."By Ray Rahman
Using cornstarch, of course.By Chris Rovzar


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COLDWORKER, the Örebro, Sweden-based band consisting of current and former members of such bands as NASUM, RELENTLESS, CARNAL GRIEF, RUIN and PHOBOS, have entered the studio to begin recording their debut album, entitled "The Contaminated Void". The band is self-producing the effort, which will be mixed by Dan Swanö and mastered by Peter In de Betou. The CD will include 14 tracks, with an as-yet-undisclosed bonus cut set to appear on the Japanese edition.To read the band's latest studio report, click here. For more information, visit Coldworker.com.
COLDWORKER Continue Work On Debut Album: New Studio Report Available
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Which sex is the worst about washing up? Why is it so important? We've got the dirty truth on how and when to wash your hands.
John's Story: Crossing the Smoke-Free Finish Line
John's story
When John Peterson is behind the wheel of his race car, he's doing more than just trying to win a race. With every lap, he's passing on a message to racing fans about not smoking.
John is a race car driver, and his team is Smoke-Free 83. With each lap, fans see John's car covered with information about quitting tobacco, including a nationwide 1-800 number they can call.
Off the track, John travels with his car and talks to fifth graders about why they shouldn't start using tobacco. The kids hear his message, sit in the race car, and even sign their names on the car.
John knows firsthand how hard it is to quit after you start using tobacco. He smoked and chewed tobacco for 16 years before he was able to quit for good.
Like many smokers, John started his habit back in high school. After smoking for 10 years, John tried to quit on his own-but he wasn't ever successful. "I actually thought I'd never be able to quit," John says. Then one day John got an e-mail about a quit-smoking class offered through his employer. He signed up-a step that put him on the right track to kicking his habit. "The class taught me how to get ready to quit," John says. That planning was the key to his success.
Lessons to learn
John had a lot to learn and plan for before he actually quit.
His first step was to understand how the addiction to nicotine worked. "I had never heard of dopamine before. It's the 'feel good' chemical of your body. Normally your body dishes it out regularly to keep you on an even keel. But in my case, my body wouldn't give me dopamine unless I gave it nicotine. My body knew that dopamine was as close as the next cigarette."
In the quit-smoking class, John learned about the destructive path that tobacco and nicotine took while traveling through his body to his brain. "I used to think tobacco only affected my lungs and my lips. I didn't realize that all of those chemicals are flowing through the rest of your body to reach your brain."
WebMD Medical Reference from Healthwise
John's Story: Crossing the Smoke-Free Finish Line Topics
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Kabbalah for the Layman
Not available
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Preview (read now) Add to my own site Add to my wishlist Author's page Publisher's page
Prior to the popularization of Kabbalah, Kabbalist Rav Berg synthesized the wisdom's key concepts into a progressive system, rather than the non-linear manner of exploration previously available. This book is the result. The kabbalistic lineage is inextricably tied to the study of the knowledge itself. To this end, Rav Berg includes historical milestones, as well as insights about master kabbalists whose lives and deaths provide a basis for learning and connection. Kabbalah for the Layman is a profound study of deep kabbalistic concepts made applicable to daily life in the 21 century. At the time of its first printing in 1981, this title was considered a revolutionary portal to expanded consciousness, Kabbalah for the Layman Volumes 1,2, and 3 became classics. Newly edited, this book contains the all three volumes for a comprehensive introduction to Kabbalah.less
Kabbalah Publishing; Read online
Title: Kabbalah for the Layman
Author: Rav Berg
Title: Kabbalah for the Layman
Author: Rav Berg
Buy, download and read Kabbalah for the Layman (eBook) by Rav Berg today!
More Religion
The Purpose Driven Life 2008 US$ 9.99 340 pages
The Wait 2016 US$ 11.99 272 pages
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Man's Search for Meaning 2006 US$ 2.99
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150 years ago, President Abraham Lincoln delivered an address he said at the time people would eventually come to forget.
Tuesday, that very same address was remembered.
The Central Pennsylvania battlefield where lincoln gave his Gettysburg Address was the site again of a ceremony attended by politicians and historians.
And a local historian says the speech has significance here as well.
The Battle of Gettysburg happened at the same time West Virginia officially became a state
"Gettysburg was a pivotal victory for us, so Lincoln said in his speech we must remember what we're doing here, and the task we must endure to finish the task," says Wood County Historian Jim Miracle. "He said we turned the tide of the war, but we weren't done with it yet."
President Lincoln hoped the noticeably brief address would help enerigize a war-torn and weary nation.


text:
Festival of Lights
The Festival is now closed for the season! Thank you for being a part of the record crowd that came out to see everything the 2015 Festival of Lights had to offer.
See you in 2016!
The Largest
Guests are treated to nearly two miles of light displays featuring more than sixty displays!
Park the car and let the holiday magic begin… Stroll the illuminated street and explore each of the buildings for unique holiday activities, shows, and more. Grab a seat for the In Jest Comedy Variety Show or the Milk for Health Kids Game Show. Climb aboard the One Buffalo Express and take a short train ride around the Festival grounds. Kids can stop in to the TOPS Winterland Workshop to make a craft. This and more is included in your carload admission.
Providing some of the most beautiful holiday photo opportunities in the area, the Fairgrounds Festival of Lights invites visitors to wander through Christmas Tree Forest where nearly one hundred trees are illuminated in thousands of twinkling lights.
The centerpiece of the Festival of Lights is the North Pole Experience. This ten thousand square foot walk through adventure leads guests through the North Pole and right to Santa's front
porch. Santa and Mrs. Claus will be greeting guests throughout the Festival as well as posing for photos, so do not forget your camera.
New in 2015! Great Lakes International Ice Carving Competition. 11 International teams will carve more than 2 tons of ice to create incredible frozen masterpieces. Carving takes place November 27-29, but all final pieces will be on display for the duration of the Festival.


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I opened a PMR with IBM and here is the answer.
There are two option:
For managing via the admin Console do the following:
1) In the Server view, double click the server on which the application is being published.
2) The Server Overview editor comes up. In the Publishing section, uncheck the option, "Minimize application files copied to the server"
3) Save the changes (Ctrl+S)
4) Remove your project from the server
5) Add your project to the server for the new changes to take effect
After performing these steps you should be able to change the startup order of your applications.
For managing startup order and other server setting for a Enterprise Project via Rad
IBM has introduce the Concept of the Enhanced Ear file (search help). Anyhow go to your ear's j2ee deployment descriptior aka. {enterprise project}/META-INF/application.xml and open an editor. You will see a tab called Deploy. This is where you can change things like startup order, enter jdbc connections etc. If and only if the keep server config in workspace is checked.
Hope this helps


text:
Senate 'Cliff' Deal Would Push Debt to $20 Trillion by 2017
From Daily Caller
By Neil Munro
The "fiscal cliff" deficit-reduction deal approved by the White House and Senate would leave taxpayers with a national debt of almost $20 trillion by the end of 2016.
The increase to the debt was downplayed in the White House's "victory" statement, which claimed that "together with a strengthening economy these [fiscal cliff] steps will bring down the deficit as a share of the economy over the next five years."
His statement claimed credit for reducing the 10-year deficit by $2.3 trillion.
A March 2012 "baseline" report by the Congressional Budget Office, which assumed that the Bush tax cuts would expire and that deep cuts in military and domestic spending would be preserved, predicted the debt would rise by $2.9 trillion from 2013 to 2022 because of annual deficit spending.
The cliff deal passed by the Senate would increase the 10-year baseline deficit of $2.9 trillion by $4 trillion, says the CBO in a report released Tuesday. That's a nearly $7 trillion increase in debt by 2022.
The deal would increase the deficits during Obama's second term by $1.7 trillion, in addition to the $1.7 trillion deficit already projected by the CBO, creating a four-year deficit of $3.4 trillion.
That $3.4 trillion in new debt by 2017 would increase the current federal debt from $16.4 trillion to almost $20 trillion in January 2017.
That's an debt increase of almost $10 trillion during Obama's two terms. The higher deficits would be primarily due to the extension of lower tax rates, known as the Bush-era rates, for individuals making under $400,000 and couples making under $450,000.
Because of the federal government's huge debt, Wall Street analysts say Obama's $4 trillion target he set in 2011 "grand bargain" talks should have been a minimal goal.
Interest rates are now at historical low levels because the U.S. and European economies are stalled.
But Wall Street analysts say interest-rates could spike if world economies improve or if they worry that U.S. politicians and taxpayers are unable or unwilling to pay the interest payments.
If interest rates reach five percent, taxpayers' annual interest-costs would reach $1 trillion per year, or one third of the federal government' 2012 tax revenues.
That annual cost would force Congress to imposed painful spending cuts or new taxes that would cripple future growth.
Obama's claim of a $2.3 trillion fiscal cliff trim was achieved by adding $620 billion in new fiscal cliff taxes to the GOP-imposed 2011 and 2012 spending cuts worth $1.7 trillion.
If fully implemented, the $2.3 trillion trim leaves the expected 10-year deficit at roughly $7 trillion. That amounts to roughly $25,000 for every one of the nation's working-age population of roughly 240 million.
When added to the current debt of $16.4 trillion, the per-worker debt would rise to roughly $80,000 per person by 2017.
Obama's claimed $2.3 reduction in the 10-year debt is small largely because he GOP opposes his push to grow the size and reach of the federal government.
For example, during the fiscal cliff talks, Obama has pushed to preserve costly spending programs, including subsidies to universities and to wind-energy programs. Overall, the deal includes $15 billion in new spending on Obama's favored programs.
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Budget cuts due to sequestration could have a major negative effect on how well the United States can gather and process intelligence, Federal Times reports.
In a briefing late last week, James Clapper, the director of national intelligence, said that the cuts would lead to the nation "accepting greater risk" and, like most other agencies, cause the need for furloughs.
READ MORE at FederalTimes.com.


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a1 Paediatric and Lifecourse Epidemiology Research Group, School of Clinical Medical Sciences (Child Health), Newcastle University, Sir James Spence Institute, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, UK
a2 Genetics Unit, Westlakes Research Institute, Moor Row, Cumbria CA24 3JY, UK
The extent to which maternal folate and vitamin B12 modulate infant birth weight is unclear. The present study investigated mothers in early gestation (mean 11·5 (sd 5·8) weeks) and neonates, at delivery. Erythrocyte (RBC) folate (mothers: n 683; neonates: n 614) and vitamin B12 (mothers: n 534; neonates: n 614) were measured. Data on smoking habits were available for 44 % of pregnancies (n 443). The relationship between vitamin levels and birth weight standardized for gender and gestational age was investigated, using linear regression and adjusting for possible confounding variables (maternal age, parity). Results are presented as standardized regression coefficients (b). Increasing maternal age was associated with elevated RBC folate (b 0·11 (95 % CI 0·08, 0·15), P<0·001; n 674) and smoking was associated with a decrease in maternal RBC folate (b −1·38 (95 % CI −1·92, −0·86), P=0·001; n 319). Neonatal RBC folate was predicted by maternal RBC folate (b 0·08 (95 % CI 0·04, 0·11), P=0·001; n 315) and maternal vitamin B12 (b 0·08 (95 % CI 0·01, 0·16), P=0·02; n 252). Smoking influenced maternal vitamin B12 status (b −0·88 (95 % CI −1·49, −0·27), P=0·005; n 231). Using univariate regression, smoking significantly influenced infant birth weight (b −2·15 (95 % CI −3·24, −1·04), P<0·001; n 437). However, the effect of smoking on birth weight was statistically non-significant when considered in a multivariate regression model, leaving maternal RBC folate as the only significant predictor of birth weight (b 0·25 (95 % CI 0·08, 0·42), P=0·005; n 145). These findings suggest that maternal folate status is an important determinant of infant birth weight. The combined effects of smoking and reduced RBC status on birth weight require further investigation.
(Received June 09 2004)
(Revised December 09 2004)
(Accepted December 09 2004)
Key Words:
c1 *Corresponding author: Dr Caroline L. Relton, fax +44 (0)191 2023060, email email@example.com


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Definition of product differentiation in English:
product differentiation
noun[mass noun] Economics
The marketing of generally similar products with minor variations that are used by consumers when making a choice.
Example sentences
- For a marketing manager, product differentiation becomes a key to gaining a degree of monopoly power in a market.
- The sachet was an innovative stroke of marketing genius that reduced product differentiation and changed the dynamics of the detergents market.
- Traditionally, medical product companies have relied on product differentiation to achieve market position.
For editors and proofreaders
Line breaks: prod|uct dif¦fer|en|ti¦ation
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= trending


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Fires stay static, but weather could fan flames
As the region's biggest fire complex approaches full containment, firefighters may have more to worry about from the coming week's weather patterns.
The National Weather Service in Spokane calls for hot, dry and unstable conditions Sunday through Friday, with temperatures near 100 degrees on valley floors. Tuesday and Wednesday may see thunderstorms and gusty winds — the twin banes of wildland fire managers.


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The International Relations Club is a lot like the NFL season. It's awesome.
It also has a lot to offer. We host grind nights where the entire club gets great deals at one of the local coffee shops on campus, the Daily Grind. We have tab nights where we pay for food at local restaurants to promote club bonding. We also have an annual beginning of the year BBQ and end of the year banquet.
On top of which, we also are home to the best intramural teams on campus. So lace up your cleats, put on your helmets, and come out and play for the IRC WMDs!
A brief outline of events is provided below.
IRC Fellows
Each Semester a seasoned international relations expert is chosen by the IRC to give an address to the College. The series was kicked off by W. Taylor Reveley, President of W&M, speaking on War powers of the President. The second speaker was Admiral Joseph Prueher, former US Ambassador to China, speaking on developing relations with China. The fellow for spring 2012 will be Chic Dambach, former President and CEO of the Peace Corps Association. The presentation is open to the public and free of charge. An open reception is usually held immediately afterward.
Intramural Sports
The IRC participates in indoor soccer, flag football, floor hockey, outdoor soccer, softball, Frisbee, volleyball, and virtually every other sport offered at the college. Whats better than #winning with a bunch of friends? So lace up your cleats, put on your helmets, and come out and play for the IRC WMDs!
To Better Know a Country
Each general meeting is opened with a member presenting on a country they have lived in or visited. Members studying abroad or friends at international schools (usually met through a MUN conference) have even been known to skype in from exotic locals.
Grind Nights
Once per semester the club descends on The Daily Grind, the campus coffee shop, for great discounts on amazing drinks and food! The only thing that's better is the discussion afterward!
Tab Nights
Returning members are welcomed back to campus in August with a tab at one of the local restaurants. There's no better way to reunite with friends than over some of the best food in town! A second tab night happens just after spring break. Jon Stewart told a club member that his favorite food in Williamsburg were the cheese fries from Paul's Deli. What's your favorite?
Late summer in Virginia has perfect weather, which demands that meals be eaten outside. Beginning the year with a cookout and repeating it again for alumni during homecoming just doubles the fun! The spring has its own fun at the grill too!
The MUNtor-MUNtee program is the new member orientation. Each returning member is paired up with an incoming member in order to introduce them to all of the facets of the IRC. MUNtors and MUNtees attend events together, such as Grind Nights and movie screenings.
End of the Year Banquet
The end of the school year is closed with a BANGquet. Seniors give wills to underclassmen, professors are invited for a screening of photos from the year, and all enjoy delicious Indian food.
The existence of this event can be neither confirmed nor denied, but word on the street (Landrum Drive) has it that the winner of this game is crowned champion of the universe.
Capture the Flag
A tradition in the first decade of the millennium, the club was divided into two teams competing across the steam between Small Hall and Dupont Hall.
Anniversary Formal Ball
Begun in Fall 2011, the Anniversary Ball celebrates the Club's founding on the fifth of November, 1931.
Service Events
The Service Committee puts on a slew of exciting events, from gardening to grow fresh and organic produce for local food shelters, outings to the plethora of local pancake houses, volunteering with Housing Partnerships, curating a silent auction, to hosting international development experts. See the service page for more information.


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New Book: "NetBeans Platform for Beginners"
By Geertjan-Oracle on Dec 29, 2013
Though the book isn't available yet, a sample PDF can already be downloaded, as you can see in the image above. Reading through the preface, it seems all core NetBeans Platform topics will be covered, e.g., System FileSystem, Lookup, Nodes, and TopComponents.
The authors would like to know, on the page above, how much you'd like to pay for the book! So, read the PDF, look at the writing style and content, and at the introduction and preface to see whether it will match your needs. Then let them know what you'd pay for it!
It will be good to have an updated book on all the core NetBeans Platform topics again.


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Belt System Question.
View Single Post
Dojo: University of Ulster, Coleriane
Location: Northern Ireland
Join Date: Oct 2000
Posts: 1,654
Hi Sean,
As far as I am aware the coloured belt system developed to encourage children in what was then becoming a 'sport'. This also helped its export to the US. I think coloured belts are useful for children, especially in aikido where it takes alot of patience to reach some degree of proficiency.
The whole idea of a grade system is a modern invention. Traditionally you would be taught martial arts individually or part of a select few. No grade would be awarded, you would just complete the training and when your teacher felt you were good enough to instruct you might end up with an instructors certificate.
Obviously everything has changed now and martial arts on the whole are taught in classes where anyone can join. Especially in the more sports orientated martial arts and martial arts directed towards childern for health education the grading system assists with competition (so similar level students can compete) and encourages people.
I think grades are useful in aikido because it helps people formalise what they know, and people can work towards gradings and feel confidence in certain techniques once grades have been achieved. However I think in many cases the full knowledge and experience of an instructor is rarely passed over to students now since there are several students at different stages of development, may of whom won't stay with the instructor to the point of being able to teach themselves.
---understanding aikido is understanding the training method---
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Associated Faculty
A. James Link
(609) 258-7191
Engineering Quadrangle, A208, A403
Lab (609) 258-4476
Research Focus
Nature has evolved and designed proteins to perform an exquisite array of tasks, but in the pursuit of biotechnological interests, these proteins must often be improved, altered, or even completely redesigned. In the post-genomic era, protein sequence information is abundant and readily available, and structural biology efforts are rapidly increasing the amount of protein structure information. However, the level of intricacy and complexity of most proteins is still such that rational design efforts are often unsuccessful in imparting an improved or new function to a protein. Fortunately, protein engineers can utilize an experimental algorithm that mimics Darwinian evolution to introduce new functions into proteins. In this algorithm, termed directed evolution, thousands or even millions of protein variants are generated by the introduction of mutations to the gene encoding the protein of interest. The library of protein variants is then screened to identify those members of the population with the highest levels of function or activity: a molecular survival of the fittest. One of the major focuses of the Link group is to apply directed evolution to medically relevant proteins.
Engineering high-affinity inhibitors of anti-apoptotic proteins
The molecular cause of several cancers is an imbalance between pro-apoptotic and anti-apoptotic proteins. It is postulated that the excess anti-apoptotic protein sequesters all of the pro-apoptotic protein thus preventing execution of apoptosis (programmed cell death). One potential treatment for cancers of this type is a high-affinity competitive inhibitor to the anti-apoptotic protein. We are pursuing several different natural proteins as scaffolds for such an inhibitor as well as completely de novo library designs.
Evolving higher efficacy antimicrobial peptides
Some classes of antimicrobial peptides are used by microbes as a defense mechanism against other species. These peptides represent an avenue of treatment for multidrug resistant (MDR) bacterial infections that has not been thoroughly explored yet. We will utilize naturally occurring antimicrobial peptides and apply directed evolution in order to engineer molecules with higher efficacies and broader spectra of activity. Synthetic biology principles are also being investigated in order to generate novel methods of delivering antimicrobial peptides to infection sites.
Biotechnological uses of E. coli: understanding the cellular response
Protein engineers often use host organisms such as E. coli simply as factories with little regard for the physiological state of the cell. We plan to use transcriptional reporters along with genomic and proteomic approaches (including BONCAT) to catalog the response of the cell to biotechnological uses of E. coli such as heterologous protein expression and unnatural amino acid incorporation. The knowledge and insights gained from these large-scale studies will subsequently be used to inform strain engineering experiments to develop host strains of E. coli that are more useful in biotech contexts.
Analyzing differential proteomes with BONCAT (Bio-Orthogonal Non-Canonical Amino Acid Tagging)
Selected Publications
Arnaudo AM, Link AJ, Garcia BA. (2016) Bioorthogonal Chemistry for the Isolation and Study of Newly Synthesized Histones and Their Modifications. ACS Chem Biol. [Epub ahead of print]
Maksimov MO, Koos JD, Zong C, Lisko B, Link AJ. (2015) Elucidating the specificity determinants of the AtxE2 Lasso Peptide Isopeptidase. J Biol Chem. 290(52):30806-12. Pubmed
Zong C, Maksimov MO, Link AJ. (2015)Construction of Lasso Peptide Fusion Proteins. ACS Chem Biol. 11(1):61-8. Pubmed
Link AJ. (2015) Biosynthesis: Leading the way to RiPPs. Nat Chem Biol. 11(8): 551-2. Pubmed
Futran AS, Kyin S, Shvartsman SY, Link AJ. (2015) Mapping the binding interface of ERK and transcriptional repressor Capicua using photocrosslinking. Proc Natl Acad Sci U S A. 112(28):8590-5. Pubmed
Piscotta FJ, Tharp JM, Liu WR, Link AJ. (2015) Expanding the chemical diversity of lasso peptide MccJ25 with genetically encoded noncanonical amino acids. Chem Commun (Camb). 51: 409-12. Pubmed
Futran AS, Link AJ, Seger R, Shvartsman SY. (2013) ERK as a model for systems biology of enzyme kinetics in cells. Curr Biol. 23: R972-79. Pubmed
Maksimov MO, Link AJ. (2013) Prospecting genomes for lasso peptides. J Ind Microbiol Biotechnol. 41: 333-44. Pubmed
Maksimov MO, Link AJ. (2013) Discovery and characterization of an isopeptidase that linearizes lasso peptides. J Am Chem Soc. 135: 12038-47. Pubmed
Maksimov MO, Pelczer I, Link AJ. (2012) Precursor-centric genome-mining approach for lasso peptide discovery. Proc Natl Acad Sci. 109: 15223-28. Pubmed
Zhang S, Long A, Link AJ. (2012) A comparison of two strategies for affinity maturation of a BH3 peptide toward pro-survival Bcl-2 proteins. ACS Synth Biol. 1: 89-98. Pubmed
Abdeljabbar DM, Song HJ, Link AJ. (2012) Trichoderma reesei cellobiohydrolase II is associated with the outer membrane when overexpressed in Escherichia coli. Biotechnol Lett. 34: 91-96. Pubmed
Zhang S, Link AJ. (2011) Bcl-2 family interactome analysis using bacterial surface display. Integr Biol (Camb). 3: 823-31. Pubmed
Abdeljabbar DM, Klein TJ, Link AJ. (2011) An engineered methionyl-tRNA synthetase enables azidonorleucine incorporation in methionine prototrophic bacteria. Chembiochem. 12: 1699-702. Pubmed
Zhang S, Prud'homme RK, Link AJ. (2011) Block copolymer nanoparticles as nanobeads for the polymerase chain reaction. Nano Lett. 11: 1723-26. Pubmed
Pan SJ, Link AJ. (2011) Sequence diversity in the lasso peptide framework: discovery of functional microcin J25 variants with multiple amino acid substitutions. J Am Chem Soc. 133: 5016-23. Pubmed
Zhang SY, Adamson DH, Prud'homme RK, Link AJ. (2011) Photocrosslinking the polystyrene core of block-copolymer nanoparticles. Polymer Chem. 2: 665-71.
Pan SJ, Cheung WL, Fung HK, Floudas CA, Link AJ. (2011) Computational design of the lasso peptide antibiotic microcin J25. Protein Eng Des Sel. 24: 275-82. Pubmed
Ferguson AL, Zhang S, Dikiy I, Panagiotopoulos AZ, Debenedetti PG, Link AJ. (2010) An experimental and computational investigation of spontaneous lasso formation in microcin J25. Biophys J. 99: 3056-65. Pubmed
Mannoor MS, Zhang S, Link AJ, McAlpine MC. (2010) Electrical detection of pathogenic bacteria via immobilized antimicrobial peptides. Proc Natl Acad Sci. 107: 19207-12. PubMed
Cheung WL, Pan SJ, Link AJ. (2010) Much of the microcin J25 leader peptide is dispensable. J Am Chem Soc. 132: 2514-15. Pubmed
Pan SJ, Cheung WL, Link AJ. (2010) Engineered gene clusters for the production of the antimicrobial peptide microcin J25. Protein Expr Purif. 71: 200-06. Pubmed
Abdeljabbar DM, Klein TJ, Zhang S, Link AJ. (2009) A single genomic copy of an engineered methionyl-tRNA synthetase enables robust incorporation of azidonorleucine into recombinant proteins in E. coli. J Am Chem Soc. 131: 17078-79. Pubmed
Sun J, Abdeljabbar DM, Clarke N, Bellows ML, Floudas CA, Link AJ. (2009) Reconstitution and engineering of apoptotic protein interactions on the bacterial cell surface. J Mol Biol. 394: 297-305. Pubmed
Tang Y, Wang P, Van Deventer JA, Link AJ, Tirrell DA. (2009) Introduction of an aliphatic ketone into recombinant proteins in a bacterial strain that overexpresses an editing-impaired leucyl-tRNA synthetase. Chembiochem. 10: 2188-90. Pubmed
Xu LY, Link AJ. (2009) Stress responses to heterologous membrane protein expression in Escherichia coli. Biotechnol Lett. 31: 1775-82. Pubmed
Link AJ, Skretas G, Strauch EM, Chari NS, Georgiou G. (2008) Efficient production of membrane-integrated and detergent-soluble G protein-coupled receptors in Escherichia coli. Protein Sci. 17: 1857-63. Pubmed
Strable E, Prasuhn DE Jr, Udit AK,...Link AJ...Finn MG. (2008) Unnatural amino acid incorporation into virus-like particles. Bioconjug Chem. 19: 866-75. Pumed
Yoo TH, Link AJ, Tirrell DA. (2007) Evolution of a fluorinated green fluorescent protein. Proc Natl Acad Sci. 104: 13887-90. Pubmed
Link AJ, Jeong KJ, Georgiou G. (2007) Beyond toothpicks: new methods for isolating mutant bacteria. Nat Rev Microbiol. 5: 680-88. Pubmed
Link AJ, Vink MK, Tirrell DA. (2007) Synthesis of the functionalizable methionine surrogate azidohomoalanine using Boc-homoserine as precursor. Nat Protoc. 2: 1884-87. Pubmed
Link AJ, Vink MK, Tirrell DA. (2007) Preparation of the functionalizable methionine surrogate azidohomoalanine via copper-catalyzed diazo transfer. Nat Protoc. 2: 1879-83. Pubmed
Link AJ, Georgiou G. (2007) Advances and challenges in membrane protein expression. AIChE J. 53: 752-56.
Dieterich DC, Lee JJ, Link AJ, Graumann J, Tirrell DA, Schuman EM. (2007) Labeling, detection and identification of newly synthesized proteomes with bioorthogonal non-canonical amino-acid tagging. Nat Protoc. 2: 532-40. Pubmed
Link AJ, Vink MK, Agard NJ, Prescher JA, Bertozzi CR, Tirrell DA. (2006) Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acids. Proc Natl Acad Sci. 103: 10180-85. Pubmed
Dieterich DC, Link AJ, Graumann J, Tirrell DA, Schuman EM. (2006) Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT). Proc Natl Acad Sci. 103: 9482-87. Pubmed
Link AJ, Tirrell DA. (2005) Reassignment of sense codons in vivo. Methods. 36: 291-98. Pubmed
Link AJ, Vink MK, Tirrell DA. (2004) Presentation and detection of azide functionality in bacterial cell surface proteins. J Am Chem Soc. 126: 10598-602. Pubmed
Link AJ, Mock ML, Tirrell DA. (2003) Non-canonical amino acids in protein engineering. Curr Opin Biotechnol. 14: 603-09. Pubmed
Link AJ, Tirrell DA. (2003) Cell surface labeling of Escherichia coli via copper(I)-catalyzed [3+2] cycloaddition. J Am Chem Soc. 125: 11164-65. Pubmed
Bradley AZ, Link AJ, Biswas K,...Platz MS. (2000) Hydrogen abstraction on photolysis of a naphthocarborane. Tetrahedron Lett. 41: 8691-94.


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SOLD ~ 8 x 8 inches ~ Oil on Canvas
Orchid-colored roses can have beautifully rich cool shadow colors, warm fuchsia tones, and even reflect a bit of blue from the sky. The rose in this painting is from the lovely rose garden at Denver's City Park (located behind the Museum of Nature and Science). I've spent many hours there photographing roses, and I find the evening light just before sunset to be the best for bringing out rich vibrant colors in the flower petals. The warm light and cool shadows are so exciting! I want to celebrate these hues that are only brought out a few hours each day. While observing roses growing in nature, I've also noticed how differently each flower opens- the petals don't always curl the same way, even with flowers on the same rosebush. While they are all roses, each one has it's own individuality, from the edges of the petals to the ends of the sepals.


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Looking back at some of the key figures in the JFK assassination
Photo: Randy Eli Grothe/Staff Photographer
Sarah T. Hughes: The federal district judge swore in Johnson aboard Air Force One at Love Field. "None of us said anything," she later recalled of the mood aboard Air Force One. "Mr. and Mrs. Johnson had been my friends for many years, but on such an occasion there did not seem to be anything to say. I embraced both of them, for that was the best way to give expression to my feelings of grief." Hughes was 66 when she died of heart failure in Dallas on April 23, 1985. (Notable: She is the only woman to have sworn in a U.S. president.)
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