text:
Horse For Sale: 11 year old (2005-04-18), 16.1H, Black ( no marks) Friesian Gelding Reg.name Rykwyn H.F (Vinny). Sired by Lammert 260 X (dam line) Marjanne…$15,000
KJ is a fun, good boy, who has a sense of humor and will make you laugh. He is 15.2 hands and is 12 years old. He listens well and is very good with kids…$2,000
Safe, been there done that pony, good for walk/trot/canter/short stirrup. Steely has been teaching kids how to ride for 16 years, and he knows his job…No Price Listed
Jasper is a flashy 16h gelding, very safe, forward ride, honest to jumps, loves his job & ready for the show season. Some limited dressage training, extensive…No Price Listed
Beautiful 15.1 h, 2002 Morgan mare (Statesmans Signature x Battersea Nica) bay with small white star. Owner going to college and looking an intermediate…No Price Listed
It is with a heavy heart that I must give up my friesian mare. Family situation has changed and I now travel for long periods of time. It breaks my heart…$12,900
Meet little guy a sweet mini who is just a really good boy very loving he's 32 in tall and weigh 200lbs I'm asking 800$800
Keeper is a beautiful 5 yr old ster mare with top bloodlines. She is 16 hands tall and is green broke to ride, doing very well under saddle. Went to her…$25,500


text:
TAMMY699 views
- Deniz
- Mystery
- Northwestern University 2012
GTA Nominee - Actress, Campus Finalist
Description: If you could change something by observing it, what would it be? And how long would it take to change it irreversibly? A movie about a girl who is using the observation effect to try and change herself.
GTA Nominee - ActressCampus Finalist
Cast & Crew

subset: commoncrawl


text:
Fred Meyer has great prices on Organic Produce this week. You can also pick up New York Steaks for $4.99 per pound. They also have an extra Holiday Savings Page where they have sweet baking prices!
Note: Some coupons/coupon values can vary by region.
Don't forget to check the Fred Meyer Coupon Policy before you shop!
They have some rules that could affect your shopping plans:
1. When buying multiples of an item, no more than 5 manufacturer's coupons for that product will be accepted in the same transaction, and only 1 manufacturer's coupon can be applied to each item.
2. Only two Internet coupons per manufacturer, per Customer, per day will be accepted.
Deals with the Blue dollar sign are good prices, not stock-up deals!
If you see any coupons below that our area didn't receive, you can always find them HERE if you would like to order them!
Have a great week!


text:
Fister toyed with American League hitters in the final month of 2011 with an array of fastballs, cutters, changeups and curve balls. In September 2011, Fister was 5-0 with a 0.53 ERA.
His 2012 season though has been sabotaged by a strained left side. Scattered success has been overshadowed by inconsistent performances. Until his last two starts.
"I think he's getting to the point where we want him to be, "his skipper Jim Leyland said. "When he makes quality pitches with that late movement, he gets outs. He's getting his strength back."
There is no doubt that Fister is regaining his dominant form.
Alex Avila caught Fister's start in Baltimore the first game after the all star break. Avila noticed a big difference.
"You can tell he is getting stronger and has more stamina," Avila said. "What you need to realize is that there is a difference between being in shape and being in baseball shape. He is finishing his pitches much better which indicates he has his arm strength back. The only way to really get it back is to pitch innings."
Bullpen sessions don't really count when it comes to building stamina.
"There is an adrenalin associated with pitching in a big league game," Avila said. "You really can't simulate it."
With a brisk, no nonsense pace, Fister's strength is keeping the opponent off balance. He has become a master at handing out a comfortable 0-4.
On Wednesday night, the right hander fanned 10 Angels on his way to eight sparkling innings. He would have come out for the 9th, but stiffened up after he was hit earlier by a batted ball.
"We just didn't want to take any chances," he said. "It was a good call."
In his last two starts, Fister has pitched 15 innings allowing only 5 hits while striking out 18 batters. September –like numbers. Fister hopes to make this September as meaningful as the final month of 2011.
Based on the latest results, Tigers fans have a reason to be excited.


text:
|All Content
|View all podcasts & RSS feeds
Podcasts & RSS Feeds
Connect with Us
Most Active Stories
News & Music Contributors
Evening Jazz Host
Sunday Side Up Jazz Host
Music Director
Business and Labor Reporter
News Director
Online Managing Editor
Morning Edition Host
All Blues Host
Midday Jazz Host
Saturday Jazz Matinee Host
All Things Considered Host
Production Manager/ Jazz & Blues Host
Environment Reporter
Morning Edition Producer
Health & Science Reporter / Assistant News Director
Midday Jazz Host
Youth & Education Reporter
Law & Justice Reporter
Sports with Art Thiel
12:06 pm
Thu September 29, 2011
Preview: Will young talent help Mariners bounce back?
Now that the dismal 2011 season has come to a close, we're looking ahead to what 2012 might hold for the Mariners.
The team added a lot of young talent to the roster this season through trades and the Major League Baseball draft. Will that be enough to help the M's bounce back?
KPLU sports commentator Art Thiel shares his thoughts on the issue tomorrow morning at 5:35 and 7:35 on 88.5 KPLU. Check back here for a blog of our commentary.
Tell us what you think!
Related Content:
Sports with Art Thiel


text:
Product prices and availability are accurate as of the date/time indicated and are subject to change. Any price and availability information displayed on Amazon.com Books at the time of purchase will apply to the purchase of this product.
Get it today!Shop Now
OrAdd to Wish List
A brilliantly insightful and witty examination of beloved and little-known films, directors, and stars by one of America?s most esteemed critics. In his illuminating new work, Gary Giddins explores the evolution of film, from the first moving pictures and peepshows to the digital era of DVDs and online video-streaming. New technologies have changed our experience of cinema forever; we have peeled away from the crowded theater to be home alone with classic cinema. Recounting the technological developments that films have undergone, Warning Shadows travels through time and across genres to explore the impact of the industry?s most famous classics and forgotten gems. Essays such as? Houdini Escapes! From the Vaults! Of the Past, Edward G. Robinson, See,? and? Prestige and Pretension ( Pride and Prejudice )? capture the wit and magic of classic cinema. Each chapter?ranging from the horror films of Hitchcock to the fantastical frames of Disney?provides readers with engaging analyses of influential films and the directors and actors who made them possible.. Price: $7.58
© Copyright 2016 - Christmas.com. All rights reserved and protected by Christmas Spirit


text:
Joyce Hall
|Joyce Hall
Joyce C. Hall founder of Hallmark Cards
|Joyce Clyde Hall
August 29, 1891
David City, Nebraska
|October 29, 1982
(aged 91)
Kansas City, Missouri
|American businessman, founder of Hallmark Cards
|Years active
|George Nelson Hall
Nancy Dudley Houston
Joyce Clyde Hall (August 29, 1891 – October 29, 1982), an American businessman, was the founder of Hallmark Cards.
Born in 1891 in David City, Nebraska, the son of Nancy Dudley Houston and George Nelson Hall, a traveling Methodist minister [3] who provided sparingly for his wife and children. When Hall was seven, his father abandoned the family. Hall worked odd jobs, mostly involving sales, from age 8 on. Hall's response to his father's mantra, "the Lord will provide," was, "It's a good idea to give the Lord a little help." In 1905, Hall and his brothers invested US$540 to buy picture postcards to sell to store owners and other dealers around their area. They also convinced some of the traveling salesmen who came into the Halls' bookstore, which Joyce Hall's older brothers bought with a partner in 1902, to add the postcards to their sales territories.[4] Hall conceived the Norfolk Post Card Company in 1908 in Norfolk, Nebraska.
In 1910, Hall moved to Kansas City, Missouri, with little more than two shoe boxes of postcards. By 1913, he and his brothers were operating a store (which would eventually evolve into Kansas City's Halls department store) selling not only postcards but also greeting cards. The store burned in 1915, and a year later, Hall bought an engraving business and began printing his own cards. It turned into a bigger business than he had had before. In 1928, he began marketing his cards under the Hallmark brand name.[5]
Hall, who objected to the name Joyce and typically went by "J.C.," retired in 1966 and spent his retirement in efforts to revitalize the Kansas City downtown area. One of the results was Crown Center, a combination business/shopping district surrounding the Hallmark corporate headquarters. Hall died in 1982 in Kansas City.
See also[edit]
- ^ http://www.evancarmichael.com/Famous-Entrepreneurs/3481/Making-His-Golden-Greeting-Joyce-Hall-is-Born.html
- ^ http://www.nndb.com/people/270/000164775/
- ^ Ancestry of Joyce Clyde Hall at the Wayback Machine (archived October 21, 2007)
- ^ [Hall, Joyce C. with Curtiss Anderson. When You Care Enough. Kansas City: Hallmark Cards, Inc., 1992. p. 23]
- ^ Hallmark History


text:
There is an issue that I feel I've been silent on too long. I would like to educate everyone on the issue of tipping your server.
My daughter started working as a server when she was in high school and continues to do so while going to college. I knew that work would be hard, but never fully understood how hard until she started waiting tables. I will say, I'm very proud of her. She is an excellent server. Unfortunately, there are a lot of people out there who still only leave $1 or $2 tips.
These servers only make $2.13 an hour. Their tips are their main income. I've even been appalled to learn that some people leave the restaurant without leaving a tip at all. These gals/guys work very hard. It's a job I couldn't do, at least I wouldn't make it past the first day because someone who was nasty to me would be wearing their food. I'm amazed at the patience my daughter has shown people who are nasty and rude.
I admire her for it. So the next time you go out to eat, remember your server doesn't even make minimum wage and leave them a decent tip. Be generous if they have done a good job - they've earned it.
Kelly Toothman
Washington, W.Va.


text:
The Stranger
by Albert Camus
The Stranger Women and Femininity Quotes
How we cite our quotes: Citations follow this format: (Part.Chapter.Paragraph). We used Matthew Ward's translation, published by Vintage International published in 1989.
Quote #10
She shouted again, "You'll get out and we'll get married!" I answered, "You think so?" but it was mainly just to say something. (2.2.7)
Whatever sense of closeness Meursault has developed for Marie was short lived; detachment is now all that is left.
Quote #11
I never thought specifically of Marie. But I thought so much about a woman, about women, about all the ones I had known, about all the circumstances in which I had enjoyed them, that my cell would be filled with their faces and crowded with my desires. (2.2.11)
Why would Meursault think about Marie? To him, she is just a generic woman.


text:
dx on d700
anybody got simple answers to simple Qs. Seems to be a lot of doom around about the DX on FX sensors. I just put my 17-55mm on my FM2 and, hey presto, the vignetting disappears as soon as it reaches its 'digital' or 'true' focal length, i.e. 24mm. Im not trying to outsmart anyone here, i just want answers before i splurge on a d700. So does this mean that all DX lenses will behave in the same way, in which case its no big deal, is it? I mean you just put a little marker at the 24mm or wherever the lens stops vignetting and away you go....this make sense....i mean we all bought the 17-55 knowing we were getting a 24mm-70 something, just turns into a 24mm-55mm on the d700, doesnt it? Id like to know, Rockwell seems to suggest that the whole affair drops to below the resolution of a D40 which it would if you were only limited to the centre 'DX' part of the sensor...but are you? Answers please guys. Many thanks
#1. "RE: dx on d700" | In response to Reply # 0briantilley Nikonian since 26th Jan 2003Thu 24-Jul-08 06:37 AM
It varies from lens to lens. The 12-24mm DX covers the FX frame from about 17-18mm upwards, but many DX lenses do not cover the FX frame at ANY focal length. The 18-200mm DX is one such.
Even if the coverage is there, you'd be using the lens in a way that wasn't intended, and image quality may fall away.
Welsh Nikonian
#2. "RE: dx on d700" | In response to Reply # 1jasonikon Registered since 13th Apr 2008Thu 24-Jul-08 08:45 AM
so in reality, it is probably better to stick with the marvellous d300 and use the dx lenses as they were intended. I often wonder at what point these advances become a little redundant. For sure the d300 was a quantum leap over the d200 but dont you think that beyond a certain point one's photographic skills/styles may begin to counterbalance the advances. I dont know, I might be talking complete rubbish, particularly since I havent even tried a d700 yet, with any lens...just trying to talk myself out of spending a whole pile of dosh on basically a new kit!
#3. "RE: dx on d700" | In response to Reply # 2Spectric Registered since 04th Nov 2004Fri 25-Jul-08 10:30 AM
Hi all
As a serious amateur I have read and studied everything to do with taking pictures & using my camera but you eventually learn that no mater how good you are at using the tools, you have no control over the light and the hardest thing to learn is actually composition.
I used to go on vacation & always take lots of images and then bin most once I got home, then as my knowledge & experience grew I would take more time at the shoot, delete the obvious no hopers there & then & only bring home the better shots. I then reached the stage where I would bring home many good shots but they were good shots of nothing, lacking a focus or point of interest & only I really knew the intentions. One thing I have learnt is that when you see a shot stop & capture it as it's no good saying I will do it on the way back !
Now I spend more time looking at a scene, evaluating it and finding the best point from which to shoot only to be defeated by the weather or light, good old british summertime !
all the best
Visit my Nikonians gallery.


text:
Analysts Stay Quiet Over Ackermann's Exit from Zurich
ZURICH—Equity analysts are often quick to comment on any changes at the companies they cover. But the surprise resignation of Zurich Insurance Group's chairman earlier this week and an investigation into the suicide of its chief financial officer, Pierre Wauthier, has elicited a deafening silence.
On Thursday, Josef Ackermann, one of Europe's top banking figures and a former chief executive of Deutsche Bank, stepped down as chairman of Zurich Insurance's board, saying Mr. Wauthier's family was in part blaming him for the death. he had been partially blamed for the suicide of , the group's CFO. Mr. Ackermann said he was leaving to protect the reputation of the insurer, the world's third largest when measured by sales.
The odd circumstances surrounding the Mr. Ackermann's departure were heightened on Friday, when the company held a conference call with analysts at which it said Mr. Wauthier had left a suicide note that referred to the relationship between the two executives. The company said it would investigate whether undue pressure had been placed on Mr. Wauthier.
Analysts had little to say after the in the wake of the unexpected disclosure.
Nomura International Plc., an arm of the Japanese investment bank, summarized the call for investors but offered little commentary. Nomura said Zurich Insurance needed to strengthen its management team and maintained its neutral rating on insurer.
That was bolder than the rest of the analyst community, which appeared to treat the topic as toxic.
Two local banks — Zuercher Kantonalbank and Helvea – commented Thursday on Mr. Ackermann's resignation. But their analysis was simple: the management change could trigger short-term uncertainty that might weigh on the stock price.
Indeed, shares of Zurich Insurance fell nearly 4% on Thursday, although they pared losses on Friday. In recent trading, Zurich Insurance was up 1.7% at 232.70 Swiss francs ($250.22).
One Swiss analyst, who asked not to be named, said the circumstances required discretion.
"The departure is apparently tied to a personal tragedy and as such is not something I would feel comfortable about evaluating," the analyst said. The situation is shrouded in speculation and will likely remain that way until there is an official explanation, he added.


text:
On top of tanning and summer flings, summer should most definitely be spent on internships. BookRenter recently partnered with InternMatch.com to create a Facebook app to offer students summer internships and extra resources on how to prepare, find, and apply for internships.
I absolutely love internships. As a student who's held multiple summer internships and internships throughout the school year, words cannot describe how valuable that experience is. Internships keep you busy and set yourself apart from others.
Places like InternMatch help students find their focus – whether their passion resides in journalism, biology, art, or theatre. It's budget friendly too – InternMatch is free for students. Students are able to save positions, get updates on various internships, and contact certain employers at no cost.
If you're interested in things like fashion, maybe check out an internship at a fashion publication. For students who are interested in public policy and government, look for internship opportunities for state leaders and political organizations.
Internships don't always have to deal with commuting either. If it's difficult for you to relocate, there are many telecommute and virtual internships available on InternMatch. InternMatch is a great resource to locate and secure virtual internships, some of which are a lot similar to the internships offered at BookRenter.
Here at BookRenter, there are many opportunities for students to thrive. Currently listed are two internships: a video production internship and a merchandising internship. Go apply!
Make your summer fun, all while networking and gaining career experience.
Good Luck!


text:
Author Affiliations: Departments of Thrombosis and Hemostasis (Drs Torn, Cannegieter, van der Meer, and Rosendaal), Clinical Epidemiology (Drs Cannegieter and Rosendaal), Neurology (Dr Bollen), and Cardiology (Dr van der Wall), Leiden University Medical Center, and Leiden Anticoagulation Clinic (Dr van der Meer), Leiden, the Netherlands.
Oral anticoagulant therapy is effective for the prevention of arterial thromboembolism in various patient groups. The increased risk of hemorrhage remains the major drawback to this therapy and is associated with the intensity of anticoagulation. Finding the optimal intensity at which the overall incidence rate of both bleeding and thromboembolic events is minimized represents a way to improve the safety of oral anticoagulant treatment.
We evaluated all patients visiting the Leiden Anticoagulation Clinic with mechanical heart valve prostheses, atrial fibrillation, or myocardial infarction from 1994 to 1998. Untoward events were major thromboembolism and major hemorrhage. We calculated intensity-specific incidence rates of untoward events to assess the optimal intensity per indication of treatment. We enrolled 4202 patients for a total of 7788 patient-years.
A total of 3226 hospital admissions were reported, 306 owing to an untoward event. Incidence rates of untoward events were around 4% per year for all indications: 4.3 (95% confidence interval [CI], 3.1-5.6) for patients with mechanical heart valve prostheses, 4.3 (95% CI, 3.7-5.1) for patients with atrial fibrillation, and 3.6 per year (95% CI, 3.0-4.4) for patients treated after a myocardial infarction. The optimal intensity of anticoagulation for patients with mechanical heart valve prostheses was an international normalized ratio (INR) of 2.5 to 2.9; for patients with atrial fibrillation, an INR of 3.0 to 3.4; and for patients after myocardial infarction, an INR of 3.5 to 3.9.
Our study suggests target INRs of 3.0 for patients with mechanical heart valve prostheses and atrial fibrillation and 3.5 after myocardial infarction as a starting point in future clinical trials.
For over half a century, oral anticoagulant therapy with vitamin K antagonists has proven its value in the primary and secondary prevention of arterial thromboembolism. Patients with mechanical heart valve prostheses are protected from valve thrombosis and ischemic stroke,1 whereas treatment in patients with atrial fibrillation2 or with ischemic heart disease prevents ischemic stroke and (recurrent) myocardial infarction.3- 5 Despite the development of new anticoagulants as direct thrombin inhibitors, vitamin K antagonists remain the keystone of anticoagulant therapy in most patients.
Now that in the aging Western society a growing number of patients are treated with vitamin K antagonists, the necessity to improve the safety of this therapy gains more and more importance. The major drawback of oral anticoagulant therapy is the increased risk of hemorrhage, which is associated with the intensity of anticoagulation and patient characteristics such as age and sex. The incidence of hemorrhage increases with higher intensities of anticoagulation,6,7 whereas the thromboembolic risk increases with lower intensities.8,9 Hence, the intensity level that provides the lowest incidence of all combined bleeding and thromboembolic events is regarded as the optimal intensity for treatment with vitamin K antagonists. The determination and implementation of the optimal intensity represents a way to improve the safety of oral anticoagulant therapy.
We previously developed a method to determine the optimal intensity level in observational studies,10 which was subsequently applied for various indications.11- 14 Some of the studies, however, were ad hoc analyses within randomized trials and could be criticized because of the small numbers of events on which the optimal intensity was based11,15 or the incompleteness of the data.12
We therefore designed a large study among patients using oral anticoagulants because they had mechanical heart valve prostheses, atrial fibrillation, or had experienced a myocardial infarction. We calculated incidences of major hemorrhage and thromboembolism and assessed the optimal intensity of treatment with vitamin K antagonists by calculating international normalized ratio (INR)-specific incidence rates.
In the Netherlands, all outpatients who are treated with vitamin K antagonists are referred to regional anticoagulation clinics to have their treatment monitored. Patients visit the anticoagulation clinic regularly or are visited at home. During each visit, a trained nurse fills in a short medical questionnaire addressing intercurrent diseases, changes in medication, hospital admissions, future interventions, and the occurrence of bleeding and thromboembolic events. A venous blood sample is taken in which the prothrombin time is measured. Prothrombin times are expressed as an INR. Laboratory procedures and materials do not change substantially during follow-up. Specialized physicians subsequently prescribe the anticoagulant dose and determine the date of the next visit. The national target INR ranges at the start of our study were 3.6 to 4.8 (for patients with a mechanical heart valve prosthesis) and 3.0 to 4.5 (for patients who had experienced a myocardial infarction and for atrial fibrillation). In 1996, after the publication of several studies of the optimal intensity oral anticoagulation,9,12,13 the target ranges were adjusted and set at INRs of 3.0 to 4.0 (for those who had a mechanical heart valve prosthesis or myocardial infarction) and 2.5 to 3.5 (for those with atrial fibrillation).
The Leiden Anticoagulation Clinic is a regional clinic in the Netherlands, serving an area with 450 000 inhabitants. The clinic annually treats over 6000 patients. In the period of 1994 to 1998, we included all patients of the Leiden Anticoagulation Clinic who were treated with vitamin K antagonists for mechanical heart valve prostheses, atrial fibrillation, or after a myocardial infarction.
The Leiden Anticoagulation Clinic routinely keeps a computerized medical record for each patient, containing all medical information that is collected through interviews at regular visits and by consulting general practitioners and medical specialists. The following data were retrieved from these records: indication for anticoagulant therapy, date of birth, sex, duration of treatment, all INR measurements with the corresponding date, hospital admissions, and death. In addition, we collected all discharge letters for the reported hospital admissions. When relevant, we also gathered results of laboratory tests, radiographs, computed tomographic (CT) scans, and autopsy reports. In this way, all thromboembolic and bleeding events that required hospital admission were registered.
Major hemorrhage and major thromboembolism were considered outcome events. Definitions of these events were adopted from previous studies.13,16 Major hemorrhage consisted of intracranial, spinal, and extracranial bleeding events. Intracranial and spinal hemorrhage was defined as neurological impairment of sudden or subacute onset, confirmed by CT scan, surgery, or autopsy. Extracranial major hemorrhage was defined as blood loss, inward or outward, leading to hospital admission for observation or treatment, or death. Bleeding events that occurred while the patient was already admitted for a different reason or admissions for diagnostic purposes only were not taken into account.
Major thromboembolism consisted of ischemic stroke, myocardial infarction, and peripheral thromboembolism. The diagnosis of ischemic stroke required an acute neurological deficit confined to the blood supply of a single brain artery and confirmed by CT scan or autopsy. Myocardial infarction was defined by 2 of the following: a history of chest discomfort, a typical rise in the level of specific cardiac enzymes above the upper limit of the reference range, or the development of new Q waves on the electrocardiogram. Peripheral thromboembolism was diagnosed as sudden peripheral ischemia, proven by duplex scanning, angiography, surgery, or autopsy.
To weigh the severity of different untoward events, we adjudicated all outcome events as serious, life threatening, or fatal. Cerebrovascular accidents (ischemic and bleeding) were considered to be life threatening when invasive procedures like surgery or angiography were needed or if they led to a modified Rankin score higher than 2 three weeks after the event occurred. The modified Rankin score measures disability after stroke on a scale of 0 to 5, at which the loss of independence in daily life begins at grade 2.17,18 Extracranial bleeding was considered to be life threatening if surgery or angiography was required or if it led to irreversible damage such as blindness or to 2 of the following: severe blood loss, hypotension (systolic blood pressure, <90 mm Hg) or severe anemia (hemoglobin level, <6.4 g/dL; to convert to grams per liter, multiply by 10.0). Life-threatening myocardial infarctions required thrombolysis or percutaneous transluminal catheter angioplasty, leading to an increase of the creatine kinase muscle-brain (MB) fraction higher than 500 U/L or to heart failure, ventricular rhythm disturbances, or hypotension. Events were considered to be fatal when the patient died as a direct consequence of the event. All other events were considered to be serious.
An expert panel classified all events according to the definitions given herein. The panel members—a neurologist (W.L.E.M.B.), cardiologist (E.E.v.d.W.), internist, and clinical epidemiologist (F.R.R.)—were at all times blinded to the intensity of oral anticoagulation at the time of the event.
The optimal intensity of oral anticoagulation is defined as the INR level that provides the lowest overall incidence of untoward events. We calculated INR-specific incidence rates as the ratio of the number of events that occurred at a certain INR level and the number of patient-years that this intensity level had been reached by the total patient population. The INR-specific incidence rates were computed per INR interval of 0.5, using the method of Rosendaal et al.10 Follow-up of the cases stopped when the event of interest occurred. The 95% confidence intervals (CIs) of the incidence rates were obtained by standard calculations, presuming a Poisson distribution of the number of events. To obtain the INR value most representative of the one at which the untoward events occurred, we collected the INR value from the hospital record on admission. If the INR was not measured on hospital admission or if the test result could not be retrieved, we used the last INR measurement at the anticoagulation clinic if the test had been performed within 8 days before the event. If no INR value was available, the event was disregarded for the calculation of INR-specific incidence rates.
We included 4202 patients who received coumarin therapy at the Leiden anticoagulation clinic for one of the study indications: 483 patients (12%) with a mechanical heart valve prosthesis (1149 patient-years), 2111 (50%) with atrial fibrillation (3476 patient-years), and 1608 (38%) who were treated because of myocardial infarction (3163 patient-years). Most patients (2820 [67%]) were already prescribed vitamin K antagonists when the study started, and 1382 patients (33%) entered the study later on when they started treatment. A total of 542 patients (13%) died during follow-up.
Table 1 presents the main patient characteristics according to the indication for anticoagulant treatment. There was a preponderance of men among patients who were treated because of a myocardial infarction (78% compared with 54% and 55% for the 2 other indications) and an older age in patients treated for atrial fibrillation (63% > 70 years compared with 41% [myocardial infarction] and 32% [mechanical heart valve prosthesis]).
In the follow-up period, 1774 patients were admitted to hospital (3226 admissions in total). Most patients were admitted for internal diseases. About one-third underwent surgery. A minority had neurologic disorders. Complete clinical information could be obtained in 3188 admissions (99%). The expert panel identified 306 outcome events that fulfilled the predefined criteria. We retrieved INRs from the day the event had occurred in 278 cases (91%). Another 10 INRs could be obtained from the medical records of the anticoagulation clinic because they had been measured within 8 days before the event. In 18 cases (6%), no INR had been measured or the test result could not be retrieved.
During the 3 years of follow-up, 122 946 INR measurements were performed at the anticoagulation clinic in the 4202 participating patients. The mean interval between 2 measurements was 3 weeks. Approximately 63% of the total follow-up time was spent within the target range, 19% below this range, and 18% above. A total of 344 person-years (4.4% of the total follow-up time) were not allocated to an INR interval because the duration between 2 measurements exceeded 8 weeks.10
Table 2 presents an overview of the primary outcome events. In patients with a mechanical heart valve prosthesis, the incidence rate of all major outcome events combined was 4.3 (95% CI, 3.1-5.6) per 100 patient-years.
Thirty-eight patients experienced a major bleeding event (3.4 per 100 patient-years; 95% CI, 2.4-4.6) of which 4 were fatal (0.3 per 100 patient-years; 95% CI, 0.1-0.8); all 4 caused by intracranial hemorrhage. The incidence of nonfatal bleeding events was 3.1 per 100 patient-years (95% CI, 2.1-4.2).
Nine patients experienced a thromboembolic event (0.8 per 100 patient-years; 95% CI, 0.4-1.4), of which 2 myocardial infarctions were fatal (0.2 per 100 patient-years; 95% CI, 0.0-0.5). The incidence of nonfatal thromboembolic events was 0.6 per 100 patient-years (95% CI, 0.2-1.2).
Nine of the 34 nonfatal hemorrhages were life threatening (2 intracranial, 7 extracranial), as were 4 of the 7 nonfatal thromboembolic events (2 ischemic strokes, 2 myocardial infarctions). Therefore, the combined incidence of fatal and life-threatening events was 1.1 per 100 patient-years (95% CI, 0.6-1.9) for hemorrhage and 0.5 per 100 patient-years (95% CI, 0.2-1.0) for thromboembolism.
The Figure shows the INR-specific incidence rates of all combined untoward events and their 95% CI per INR level. The lowest incidence was found at an INR of 2.5 to 2.9: 2.0 per 100 patient-years (95% CI, 0.2-5.7). At higher INRs (≤4.5), incidence rates increased only slightly to a maximum of 2.6 events per 100 patient-years for an INR of 4.0 to 4.5. In contrast, incidence rates rose rapidly from 6.7 per 100 patient-years (95% CI, 0.6-19.4) for an INR of 2.0 to 2.4, up to 51.8 per 100 patient-years for an INR of 1.0 to 1.4, and from 4.7 per 100 patient-years (95% CI, 1.4-9.8) for an INR of 4.5 to 4.9, up to 55.3 per 100 patient-years (95% CI, 28.0-91.9) for an INR greater than 5.5.
International normalized ratio (INR) specific incidence rates. Rates are shown for patients with a mechanical heart valve (A), atrial fibrillation (B), and myocardial infarction (C). Dashed lines indicate 95% confidence intervals.
In addition, we calculated INR-specific incidence rates exclusively for the most severe untoward events (life threatening or fatal). As shown in Table 3, the anticoagulant intensity that provided the lowest incidence rate of untoward events remained the same.
The combined incidence rate of all major outcome events in patients treated because of atrial fibrillation was 4.3 events (95% CI, 3.7-5.1) per 100 patient-years (Table 2). Ninety-seven patients had experienced a major bleeding event (2.9 events per 100 patient-years; 95% CI, 2.3-3.5), of which 14 were fatal (0.4 events per 100 patient-years; 95% CI, 0.2-0.6): 11 caused by intracranial bleeding, 3 caused by extracranial bleeding. The incidence of nonfatal hemorrhages was 2.4 events per 100 patient-years (95% CI, 1.9-2.9).
Forty-nine patients experienced a thromboembolic event (1.4 events per 100 patient-years; 95% CI, 1.0-1.9). Nine were fatal, all caused by myocardial infarction (0.3 events per 100 patient-years; 95% CI, 0.1-0.5). The incidence of nonfatal thromboembolic events was 1.2 events per 100 patient-years (95% CI, 0.8-1.5).
Seventeen of the 83 nonfatal hemorrhages were life threatening vs 13 of the 40 nonfatal thromboembolic events. The incidence of fatal and life-threatening events combined was 0.9 events per 100 patient-years (95% CI, 0.6-1.2) for hemorrhage and 0.6 per 100 patient-years (95% CI, 0.4-0.9) for thromboembolism.
We found the optimal intensity of oral anticoagulant treatment in patients with atrial fibrillation to be an INR of 3.0 to 3.4 (Figure). In this intensity range, the incidence rate of untoward events was 2.4 events per 100 patient-years (95% CI, 1.5-3.5). Lower INRs led to higher incidence rates: from 2.6 events per 100 patient-years (95% CI, 1.5-4.0) for INRs of 2.5 to 2.9, up to 32.9 per 100 patient-years (95% CI, 10.1-68.9) for INRs less than 1.5. High intensities yielded incidence rates of 2.6 events per 100 patient-years (95% CI, 1.6-3.9) for INRs of 3.5 to 3.9, 9.0 per 100 patient-years (95% CI, 4.6-14.9) for INRs of 4.5 to 4.9, and up to 42.3 per 100 patient-years (95% CI, 29.2-57.8) for INRs greater than 5. When we excluded myocardial infarction as an outcome event, arguing that patients with atrial fibrillation are treated with anticoagulation agents because of their risk of ischemic stroke, not myocardial infarction, the optimal intensity stayed the same. When we limited the untoward events to life-threatening and fatal cases (Table 3), the incidence rates were lower at INRs of 2.0 to 3.0 (0.6 events per 100 patient-years; 95% CI, 0.2-1.2) compared with an INR of 3.0 to 4.0 (1.0 events per 100 patient-years; 95% CI, 0.6-1.6).
The incidence rate of all untoward events in patients treated after a myocardial infarction was 3.6 (95% CI, 3.0-4.4) per 100 patient-years (Table 2). Fifty-three bleeding events occurred (1.7 per 100 patient-years; 95% CI, 1.3-2.2), of which 5 were fatal (0.2 per 100 patient-years; 95% CI, 0.0-0.3). The incidence of nonfatal hemorrhage was 1.5 events per 100 patient-years (95% CI, 1.1-2.0).
Sixty thromboembolic events occurred (1.9 per 100 patient-years; 95% CI, 1.5-2.4). Thirteen recurrent myocardial infarctions were fatal (0.4 events per 100 patient-years; 95% CI, 0.2-0.7); the incidence rate of nonfatal thromboembolic events was 1.5 per 100 patient-years (95% CI, 1.1-2.0).
Eleven hemorrhages (3 intracranial and 8 extracranial) were life threatening, as were 25 myocardial infarctions. The incidence of life-threatening and fatal events combined therefore became 0.5 per 100 patient-years (95% CI, 0.3-0.8) for hemorrhage and 1.2 per 100 patient-years (95% CI, 0.8-1.6) for arterial thromboembolism.
We found the lowest incidence of untoward events to be an INR of 3.5 to 3.9 INR (Figure), yielding an incidence rate of 1.1 per 100 patient-years (95% CI, 0.5-1.9). Lower intensity levels yielded higher incidence rates, varying from 1.6 events per 100 patient-years (95% CI, 0.9-2.6) for INRs of 3.0 to 3.4, up to 13.7 events per 100 patient-years (95% CI, 0-54.8) for INRs of less than 1.5. Higher intensities led to incidence rates of 3.6 events per 100 patient-years (95% CI, 2.1-5.6) for INRs of 4.0 to 4.4, up to 40.3 per 100 patient-years (95% CI, 27.8-55.0) for INRs of 5 or greater. When we analyzed only life-threatening and fatal events, the position of the optimal intensity did not change (Table 3).
We performed a cohort study among patients of a Dutch anticoagulation clinic to calculate incidence rates of bleeding and thromboembolic events and to identify the optimal intensity of oral anticoagulant therapy for patients with cardiac sources of arterial thrombosis: mechanical heart valve prostheses, atrial fibrillation, and myocardial infarction. The incidence rate of all untoward events was similar for all 3 indications, around 4% per year. To date, these numbers have been stable. The optimal intensity of anticoagulation, at which the overall incidence rate of both bleeding and thromboembolic events is lowest, did not differ much among the 3 indications. It was located at an INR of 2.5 to 2.9 for patients with mechanical heart valve prostheses, at an INR of 3.0 to 3.4 for patients with atrial fibrillation, and at an INR of 3.5 to 3.9 for patients treated after a myocardial infarction.
Before suggesting optimal target levels for oral anticoagulation in daily practice, 2 additional issues have to be addressed. First, it should be assessed whether the protective effects of oral anticoagulants outweigh the introduced bleeding risk because we would otherwise just exchange one risk for the other. Within the ranges with the lowest incidence rates, the incidence of all major untoward combined events was 2.0 per 100 patient-years for patients with mechanical heart valve prostheses, 2.4 per 100 patient-years for patients with atrial fibrillation, and 1.1 per 100 patient-years for patients after a myocardial infarction. The incidences of major thromboembolism in these patient groups without anticoagulant therapy have been estimated at 5.8 per 100 patient-years,1 4.5 per 100 patient-years,2 and 6.9 per 100 patient-years,12 respectively, indicating that the use of oral anticoagulants is beneficial in all 3 indications. It is important to note that the concomitant use of vitamin K antagonists and antiplatelet agents was highly uncommon in the Netherlands because of the increased bleeding risk.
Second, the severity of thromboembolic and bleeding events may not be judged as similar. Therefore, we weighed all outcome events as serious, life threatening, or fatal and separately analyzed the most severe events only. The position of the intensity range with the lowest incidence of these untoward events did not change for patients with mechanical heart valve prostheses or for those after myocardial infarction but tended to be lower for patients with atrial fibrillation.
The data presented herein suggest the following target levels for oral anticoagulation in the prevention of arterial (thrombo)embolism: an INR of 3.0 for patients with mechanical heart valve prostheses, 3.0 for patients with atrial fibrillation, and 3.5 for patients after myocardial infarction.
Still, it is important to realize that the optimal (target) levels we found should be interpreted cautiously because the design of our study has its limitations. Despite the large patient groups and substantial follow-up period of 3 years, the absolute number of untoward events remains relatively small. Although clear patterns are shown, the statistical precision of the outcomes is therefore limited. Another shortcoming of the study design might be that few patient characteristics or individual clinical parameters were taken into account. One might argue, therefore, that although the study results apply to the group as a whole, individual patients may have different risks at different intensities. Although this is undoubtedly true, very large studies would be required to estimate these individual risks. It is highly uncertain if such studies will ever be performed.
Yet, the study design has major advantages as well. The important features are that we used actually achieved INR levels to calculate the optimal target intensities irrespective of the targets used. Furthermore, we performed a study in the routine setting of an anticoagulation clinic, preventing bias from nonroutine, more intense monitoring. For this reason, the study results can easily be applied to day-to-day practice.
Now that we have defined the presumed optimal intensity of oral anticoagulation for patients with mechanical heart valve prostheses, atrial fibrillation, and after myocardial infarction, testing these ranges in new clinical trials should be considered. These trials could compare current target ranges with the optimal intensity levels we found and provide us with a final answer as to which INR level is safest for patients at high risk of arterial thromboembolism.
Correspondence: Frits R. Rosendaal, MD, PhD, Department of Clinical Epidemiology, Leiden University Medical Center, Building 1, C7-P, PO Box 9600, 2300 RC Leiden, the Netherlands (email@example.com).
Accepted for Publication: March 13, 2009.
Author Contributions:Study concept and design: Torn, Cannegieter, van der Meer, and Rosendaal. Acquisition of data: Torn, Bollen, and van der Meer. Analysis and interpretation of data: Torn, Cannegieter, van der Meer, van der Wall, and Rosendaal. Drafting of the manuscript: Torn. Critical revision of the manuscript for important intellectual content: Cannegieter, Bollen, van der Meer, van der Wall, and Rosendaal. Statistical analysis: Torn, Cannegieter, and Rosendaal. Obtained funding: Torn, Cannegieter, and Rosendaal. Administrative, technical, and material support: van der Meer and Rosendaal. Study supervision: Bollen, van der Meer, and Rosendaal.
Financial Disclosure: None reported.
Funding/Support: Funding was provided by the Netherlands Heart Foundation and the Prevention Fund and the Dutch Thrombosis Foundation.
Thank you for submitting a comment on this article. It will be reviewed by JAMA Internal Medicine editors. You will be notified when your comment has been published. Comments should not exceed 500 words of text and 10 references.
Do not submit personal medical questions or information that could identify a specific patient, questions about a particular case, or general inquiries to an author. Only content that has not been published, posted, or submitted elsewhere should be submitted. By submitting this Comment, you and any coauthors transfer copyright to the journal if your Comment is posted.
* = Required Field
Disclosure of Any Conflicts of Interest*
Indicate all relevant conflicts of interest of each author below, including all relevant financial interests, activities, and relationships within the past 3 years including, but not limited to, employment, affiliation, grants or funding, consultancies, honoraria or payment, speakers' bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued. If all authors have none, check "No potential conflicts or relevant financial interests" in the box below. Please also indicate any funding received in support of this work. The information will be posted with your response.
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
The Rational Clinical Examination: Evidence-Based Clinical Diagnosis
Original Article: Does This Patient Have a Hemorrhagic Stroke?
All results at
JAMAevidence.com >
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Need assistance?
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.


text:
Watch A Clip from Pixar's First TV Special 'Toy Story OF TERROR!'
Until he was at the helm of Pixar Animation Studios' first television special "Toy Story OF TERROR!" it never occurred to director Angus MacLane to substitute a 99-cent rubber bat for a computer generated effect.
"If we did CGI, it was going to cost $1 million, and we just didn't have that kind of money for effects," said MacLane. The bat makes a cameo in the 22½ – minute feature "Toy Story OF TERROR!"
The Halloween-themed special takes characters from the studio's "Toy Story" franchise—including Woody (voiced by Tom Hanks), Buzz Lightyear (Tim Allen), Ken (Michael Keaton) and Jessie (Joan Cusack)—and places them in a dumpy motel after a flat tire upset their horror film laden drive to Grandma's house.
The film debuts at 8 p.m. on Oct 16 on ABC, which, like Pixar, is owned by The Walt Disney It also marks the second time in Pixar history (after "Brave") that a female character, Jessie in this case, is the main protagonist in one of the company's movies.
"The story development process actually revealed to us that Jessie was the best candidate to focus on," said Andrew Stanton in an email. "She already had a well-established fear [of being in small, tight places], and that's the core emotion of the horror genre."
Stanton, who co-wrote all three "Toy Story" films, guided MacLane through the storyboarding process and ultimately aided in getting the film green lit.
Watch an exclusive clip from "Toy Story of TERROR!"? Leave your thoughts in the comments.
Follow @alexandracheney for more film and television news.


text:
The 381,600 households in the Hudson Valley could pay almost a half-billion dollars more this winter than last to heat their homes, Sen. Charles Schumer said Wednesday as he announced a plan to dramatically expand the federal Low Income Home Energy Assistance Program.
"You ain't seen nothin' yet," Schumer said, referring to the impact oil prices have had on the average New Yorker. "The price of gas is up, the price of electricity is up, but the price of heating oil is through the roof."
To address the crisis, Schumer is joining with a bi-partisan group of senators introducing new legislation, S.3186, the Warm in Winter and Cool in Summer Act, which would provide $2.53 billion in additional emergency funding to LIHEAP, which provides direct assistance to low-income families and seniors who are struggling to pay their bills. Schumer is also asking President Bush to release an additional $120 million in emergency LIHEAP aid to get the money flowing right away.
In the House, 21 members from the Northeast asked Wednesday to more than triple federal home heating aid this winter. The lawmakers sent a joint letter to House Speaker Nancy Pelosi asking for as much as $9 billion in heating aid to be included as part of a new economic stimulus bills. They also requested up to $1 billion for weatherization programs to help homeowners conserve energy and save money.
Millions of poor and elderly people on fixed incomes rely on LIHEAP to help pay their bills, and Congress appropriated $2.57 billion for low-income home energy assistance last winter.
The House members warned that soaring energy costs will make it difficult for millions of families to pay for both heating their homes and buying enough food, With home heating oil prices already over $4 a gallon, many households in New England will be paying upward of $4,000 to heat their homes this winter, they said.
The U.S. Department of Energy estimates Hudson Valley households will pay almost $275 million more to heat their homes this winter than last, while the New York State Energy Research and Development Authority's figures are even grimmer, estimating the increase at almost a half-billion dollars.
The Associated Press contributed to this story.
Location, ST | website.com


text:
Interesting Stuff – June 27, 2009 Edition
Each week, on Saturday, I'm publishing links to some of the things I've come across over the past week that might (I repeat "might") be of interest to you. These are things that stimulated me in some way related my practice. I'm publishing these links without much comment so you'll have to click on them if they look interesting to you.
Twitter Client Development Success Stories – Kevin O'Keefe has gathered these stories and it's worth checking out if you still question the value of Twitter as a business development tool.
Priming the pump of efficiency – Seth Godin writes about the cost of updating systems. This inspired me to get moving on trashing our old client database system and moving toward something new.
What if the Apple Store billed by the hour? – Well done by post by Jay Shepherd.
How Facebook is Gunning for Google (And Killing SEO) – written by attorney Mike Wasylik about the huge impact Facebook is having on traffic to other websites.
Photo by Jose Luis Mieza


text:
National Heart, Lung, and Blood Institute; Notice of Closed Meeting
Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the following meeting.
The meeting will be closed to the public in accordance with the provisions set forth in sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions could disclose confidential trade secrets or commercial property such as patentable material, and personal information concerning individuals associated with the grant applications, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy.
Name of Committee: National Heart, Lung, and Blood Institute Special Emphasis Panel; Resource-related Application in Congenital Heart Diseases (R24).
Date: April 17, 2012.
Time: 1 p.m. to 3 p.m.
Agenda: To review and evaluate grant applications.
Place: National Institutes of Health, 6701 Rockledge Drive Bethesda, MD 20892, (Telephone Conference Call)
Contact Person: Keary A Cope, Ph.D., Scientific Review Officer, Office of Scientific Review/DERA, National Heart, Lung, and Blood Institute, 6701 Rockledge Drive Room 7190, Bethesda, MD 20892-7924, 301-435-2222, firstname.lastname@example.com
(Catalogue of Federal Domestic Assistance Program Nos. 93.233, National Center for Sleep Disorders Research; 93.837, Heart and Vascular Diseases Research; 93.838, Lung Diseases Research; 93.839, Blood Diseases and Resources Research, National Institutes of Health, HHS)
Dated: March 15, 2012.
Jennifer S. Spaeth,
Director, Office of Federal Advisory Committee Policy.
[FR Doc. 2012-6954 Filed 3-21-12; 8:45 am]


text:
On Mar 20, 3:15 pm, Petry
> Hello,
> I need some information about the system i started to admin recently:
> * Need to map the file system ( name, size, % of use, which are
> storage which are local disk )
> I use df -k, so i get name, size and % of use... but to see if are
> storage or local disk i cant see whith this command..
> * I need to she Hardware information ( i know is a Fujitsu machine,
> but i need to know the model )
> Is it possible to see using a command?
> * I need to see what HBA are installed in the server, and some
> information abou these HBAs installed: Model, Drive and Firmware..
> * OS of the server
> uname -a
> SunOS metrica 5.8 Generic_117350-45 sun4us sparc FJSV,GPUZC-M
> That is all? Maybe FJSV ( Fujitsu ) and GPUZC-M the model ?
> * Cluster software that is installed and version
> I saw on /var/sadm/system/admin/CLUSTER and get the name SUNWCXall..
> is that all? And how i see the version?
> * I need to see which Volume Manager is installed ( model and
> version )
> Tks by now!
You should try downloading a script called cfg2html which basically
will gather all the info about your box creating a HMTL page will all
the information about it.


text:
Weebly Overhauls Website Launching Pad
Websites are starting to seem pretty old school, as businesses rush to use Facebook, Twitter and other newer mechanisms to reach customers. Weebly doesn't see it that way.
The oddly named startup, founded by three Penn State students in 2006, operates one of best-known services to help create sites without complexities like learning HTML. Weebly also hosts those sites; the San Francisco startup counts 15 million of them now, attracting visits from more than 100 million unique visitors a month.
Though seemingly doing pretty well already, Weebly on Thursday is overhauling its service and more forcefully making the case that websites still matter.
"We did a ton of consumer research," says David Rusenko, the company's 27-year-old CEO.
The findings, no surprise, are in line with the company's strategy. Weebly says 56% of consumers who responded in a survey it conducted through Googleid they don't trust a business without a website.
Weebly says it has surveyed three million people who created sites using the service; 98% of respondents said a page on Facebook is no substitute for a site. (Not that the social network might not help customers find you on the Web, of course). Yet 58% of businesses still don't a website, Weebly says, an indicator it has more work to do.
The overhaul Weebly is announcing Thursday–along with a catch phrase, "Start Something"–includes changes that touch on trouble spots for many users. One of them, Rusenko says, is that people simply don't have a vision for what a site should accomplish. It is offering a new site planner to tool to help think through those preliminary steps.
Another addition is a tool that helps customers craft how their sites may look on mobile devices. Though some companies may see a need to create full-featured apps, that approach is simply not feasible for most businesses.
"No one is going to download an application for their local coffee shop," Rusenko says.
While Weebly has many competitors, it boasts some unusual attributes among Web startups. For one thing, the company says it has been profitable since 2009, exploiting the business model known as "freemium." Most of its users pay nothing, but some pay $4 to $8 a month for extra features.
There's also been no turnover at the top. Dan Veltri and Chris Fanini, both 28, still play major roles.
And, while many startups let others like Amazon Web Services run servers for them, Weebly still operates its own systems in a well-connected San Francisco building (along with a backup site in Las Vegas). The Weebly founders say that greater security and reliability of the strategy outweigh any headaches associated with buying and maintaining the machines.


text:
20 Indoor Movement Activities
Physical activity throughout the school day is necessary for children to reenergize themselves and to be able to maintain focus on their school work. Many teachers notice fewer behavior problems when children are provided with many opportunities to move. here are 20 Indoor Movement Activities to help you get your students moving for their health - and yours!
— Submitted by Kathleen Carpenter (Teachers.net), NEA discussion board


text:
Earl of Orford LbNA # 15843 (ARCHIVED)
|Collins Clan
|Placed Date
|Jun 16 2005
|Found By
|Last Found
|Hike Distance
This box has been taken (sadly)...It wasn't in danger of flood waters & was checked afterwards for damage..so until we can replace it, it is currently out of commision. Sorry!
Please do not think this mystery letterbox is completely cheesy, there are many holes in it. Don't get bogged down with all the details. Today, it is still all relative!
One and two make three, Find the town that was granted No. 3 in 1736. If you're keen, head north up one and two, as the heroic U.S. Senator from Massachusetts would have, if the road had been here during the American Revolution.
When you enter Town No.3, you may feel you need a "rest"- Miss Alcott and Miss Dickenson "stop"ped here too.
Look for the "trees" named after the Senators great granddaughter to take a rest. BEWARE!! there are two of these, So stay away from the side of the river! Instead cross the road, go past the rock, and up the stairs, into the woods.
At the top of the stairs take a sharp left, follow the path along the ridge of the hill (Do not take small paths off the sides of it- stay straight!) When the hill starts to go down again, look ahead for a pile of trees (logs about 2 feet in diameter) they will be just in front of a wire fence. Look in the end of the pile of three, behind a piece of bark.
Please rehide in the same place. When you turn around you'll see a short cut back to the parking lot.
This is an easy "Drive By", once you figure out where it is, of course! Have fun....
Please let us know what you think and any problems
The Collins Clan
Please note:
There are some steep areas!! Keep little ones near, the path to the right has a big drop off.That is why we planted it to the left. If you have little ones, stay left. Thanks


text:
Posted: Wed Dec 14, 2011 4:24 pm
Post subject:
hi everyone!!
i hvent been on here for ages as busy being a mummy to Emilia
Charlene i was due 28 oct and had emilia on 4th Nov! at half 4 am xx
Emilia is so long she was only in new born clothes for a few days and is fast out growing her 0-3 clothes !
i am breastfeedubg exclusivly which i am loving althoug on her 'hungry days; can get very tiring
i had the nasty rash come back which was making me miserable and scratching very bad espec at night but with tablets its slowliy going but they may never know what it was
Emilia is gaining weight well and was up to 11.4 last week, we have a sort of routine of feeds/naps in the day but nights are vbery hard. she suffers from colic and is up/dow #n screaming and gets un a right state bett 10n#pm-2am
after that when i finally get her settled she usually sleeps throygh till 8am!
im unable to put her down awake, she sleeps on me while winding/after a feed or needs to be rocked gently to sleep. a bit worried this is bad habit forming what do you think or is it ok as shes so young?
be glad of your opions and thoughts on it all as the health visitor tells me to put her down awake but she getss into some right states crying with her colic and i want to comfort her to get her settled.
how are you all getting on with your babies? i can't beleive shes over a month old already!
looking forward to your family chrismases?
Posted: Wed Dec 14, 2011 7:13 pm
Post subject:
Hi ladies! Well I wasn't meant to be a November mummy, but wanted to let you all know baby George Martin arrived on the 12th of December at 21.05pm, 12 days late weighing 10lb 5 1/2oz and 60cms long. All went brilliantly and we're home and so so contented. He doesn't even mind his big sister bashing drums by his head Hope you're all having good times with your little ones xxx
Posted: Thu Dec 15, 2011 12:54 am
Post subject:
leanne the days do go fast i cant believe hes almost 3weeks but matbe thats because he was 4days old before i got to be a proper mummy and not just look at him through a cot
bunny i know how you feel kieran has colic and a virul infection and if i put him down awake he screams because the pain my health visitor said to give him lots hugs and put him in our bed feeding till he falls asleep, im also fully breast feeding which surprised her due to his birth, i hand expressed my colosum so i could feed kieran myself
charlene congrats on the birth of nathan lovely name hope your recovering well my section was an emergency to
stacey congrats again xx
Posted: Wed Dec 21, 2011 1:33 pm
Post subject:
Where have all you November mummies gone? lol
Well We took Amelia-Rose for her hip scan last Thursday, she was as good as gold when the sonographer scanned one hip but when she turned her over to scan the other one she started really screaming which is a little bit worrying but Amelia-Rose doesn't seem like she's having problems with either of her hips, she really kicks her legs when she gets stressed out lol fingers crossed should get a letter soon with the results.
There was also a set of baby scales in the Mother and Baby room so we weighed her and she weighed just under 9lb so she's putting on weight which is good, she's getting so big though, can't believe she's 6 weeks tomorrow Where has the time gone? We have an appointment on Friday with the clinic to go get her weighed and that there and she has to get her injections from the doctor on 6th January really not looking forward to that although she didn't even flinch when she had her heel prick test so i'm hoping she'll be ok.
Does anyone know if you can combination breastfeed with the Aptamil for hungry babies? i'm not breastfeeding as much as i was as there was a few days i didn't do it due to feeling run down and she's getting more aggitated when she's trying to feed off me due to lack of milk i'm producing as a result of that, I'm scared to use my breast pump as on Friday I used it and about 15 mins after Mark had to call an ambulance as i started getting pains in my chest and couldn't breathe properly, i was taken to hospital and had blood taken, ECG and an x-ray but they couldn't find anything wrong so they think using the breast pump may have triggered spasms in the muscles or something although i'd never had any problems previously. I still want to breastfeed though
Hope all mums and babies are doing well
Posted: Thu Dec 22, 2011 8:00 am
Post subject:
I used to rock tyler to sleep and we managed to get him out of the habit, our babies are so young that it's ok to give cuddles if they need it they won't want them forever! I don't think there is anything wrong with combination feeding either, finlay gets one bottle of expressed breast milk and the rest formula and he's fine.
Posted: Thu Dec 22, 2011 9:47 am
Post subject:
Hi all
Sounds like everybody is doing well. Cleo is now7wks old and 10lb 9oz and 55cm long. She's a happy wee thing and smiles and chuckles all the time. She tells huge big stories too She's sleeping from 10 till about 4 or 6 then i wake her at 10, or she sleeps right through till 8. We have a bedtime routine now but days are pretty hit and miss. Depends on how hungry she is and how much she wants to eat in one sitting.
Is anybody still bleeding? I've been bleeding pretty constantly for 7wks and its really starting to annoy me. I went back on the pill 3wks ago and am on my break. Hope to have a good period so it empties my womb so i don't bleed anymore. Will be going back to the docs after the new year if it hasn't stopped by then. They should scan me to look right????
Anyhoo we're all doing well x
Posted: Thu Dec 22, 2011 2:18 pm
Post subject:
ahhh Dee I can only dream about Finlay going through the night
he's not that bad though getting better.
how the fluff have you managed to sort out a bed time routine? I dont seem to have time to bath Finlay before his last bottle as he always wants a feed between 5 and 8 which is dinner and bath time for Tyler. ugh Im sure it will get easier
7 weeks is a long time to bleed hun have you had your postnatal check? it could be to do with going on the pill though. I stopped bleeding about 2 weeks ago.
Posted: Wed Dec 28, 2011 10:19 pm
Post subject:
Hey Dee I am still bleeding too and Calum is 8wks! But I have gone back on contraceptive inject so think that why-blooming pain though!
We are all doing good, though Calum has been VERY hard work as he is colicky in the evenings. Touch wood we have had 2 good nights in a row though so hopefully there is light at the end of the tunnel!!! He is such a gem when contented but these past few days, if he has been awake, he has been crying. Think he has had the cold to though do that not helped.
Getting into a routine at nigh though which making things easier and he a pretty good sleeper, usually just up the once, sometimes twice.
I do remember though with Iona that this phase passes so quickly that we will all soon be looking back and wondering where our 'baby time' went!!! (although I do look forward to the nights when we dont have to get up!!!!)
Hope you are all well and had nice christmases with your wee ones!
Posted: Thu Dec 29, 2011 9:13 am
Post subject:
Jade - bedtime routine starts at 9pm so Mia's already in her bed by then. They don't do 6wk checks here at all. If i want it i have to make the appointment.
mpat - ooh the injection yuck i would never touch that again. I bled for a constant 13wks on it and never went back for the next one as well as a lot of side effects.
Had a pretty heavy period last week and seem to have stopped bleeding for the past 2 days so fingers crossed it cleared me out. Cleo is growing so fast. She's getting really long now and her toes are starting to go tight in the feet of the sleepsuits. She's got a cute wee chuckle now and a wee personality You can tell what she's saying by how she looks at you now and she loves to shout at you if you don't feed her fast enough. Mia loves her to bits to and keeps sayin hiya to her lol
Christmas was nice and quiet just how i like it and my babies got spoiled rotten. Mummy ate loads of turkey and all the trimmings Diet in the new year for me i think.
Hope your all fab and had a good chriatmas.
Posted: Sat Dec 31, 2011 2:55 pm
Post subject:
We had a great christmas, tyler was really into it this year I can't wait til next year now 7
These past few days finlay has turned into a screamer and doesn't seem to be happy with anything...i think it's just colic but it's still awful to listen to, he also isn't getting any better at night, wanting feeds every 3 hours it's starting to take it's toll now but like mpat said we'll be wondering what happened to our babys before we know it.
Posted: Tue Jan 03, 2012 10:06 pm
Post subject:
Happy new year everyone!
Emilia has her first jabs tomorrow morning I'm not looking firwArd to!
I'm still exclusively breastfeding and her weight up to 12.6 the week before Christmas. She's akeeay in her own cot and room ( in sleeping bag) as kept waking herself up in the moses basket when she stretched as she's so big! I know it's not recommended befire. 6 months but had to be done and we have monitors and I check on her.
We have had some awful colic nights been in tears myself but has started getting better, gripe water has seemed To be the most help.
Starting a bath and feed routine before every bed time frim 8 every night this week, usually takes 2 hr TI get her down asleep then sleeps thu 11-6
Just trying to pull it forward and be able to get her to settle self to sleep any Advice And tips appreciated !!!
Take care everyone xxx
Posted: Wed Jan 04, 2012 5:09 pm
Post subject:
Hi all, been a while since i posted in this thread, i hope you're all ok.
Amelia-Rose has her immunisations tomorrow morning which i'm not looking forward to at all and then i have my post-natal check straight after.
Also, i'm so tired, i'm sleeping most of the day. My OH doesn't get in from work until about 11pm and then we eat dinner when he comes home, by the time we've finished and spent a little time with eachother there's no point going to bed as she feeds between 1-2am and then it takes an hour to feed/wind her so sometimes we don't get to sleep until about 3-ish and if she's being restless sometimes later than that. Her next feed is between 5-6am so we sleep between that feed and then we go back to sleep until her next feed between 9-10am and then again the feed after so i'm not getting out of bed until about 1-2pm, stay awake for a few hours and i'm tired again so end up going back to sleep for a few hours and then the same thing happens all over again.
I'm not getting all my housework done or anything but i just can't stay awake and am tired all the time. I'm on iron levels due to losing half my blood during c-section and then having transfusion. i'm also on anti-depresessents so don't know if that's contributing towards my tiredness...... help
Posted: Sun Jan 08, 2012 10:33 am
Post subject:
Bunny I found with tyler that the more we tried to get him into a routine the more he fought it! He didn't serif settle for a while and it's something you have to teach them! Try the pouch up put down method.pouch up when they cry but as soon as they stop put them back. You can pat and sshhh them to help them go off but should only pick up when they cry and straight back down when they stop.
Lianne it sounds like normal newborn baby tiredness! When she starts sleeping for longer periods of time I'm sure you'll start to feel better
Posted: Tue Jan 10, 2012 3:11 pm
Post subject:
Hi everyone hope ur all ok and babies r doing well. I haven't been on for a while been busy but enjoying it. I had to give up breast feeding at 6weeks as i wasn't producing enough milk no matter wot i tried. I started to get sore and Ethan was starting to get stressed, which i hated as he is such a happy and content baby. Been bottle feeding him completely for 3wks now and it was def best option for us. I would def b/f again but would do wot i did with Ethan and put them on bottle when i can't manage no more.
Anyway i got Ethan weighed the day of our 6wk check he was 9lb2oz then. That was nearly 3wks ago. He has out grown his newborn clothes he is so long but not very chubby How often do u weigh babies now the h/v has stopped coming round to do it? I read once a month is this right?
We had a great 1st christmas together and Ethan was really spoilt. It was the 1st time in 5yrs me and OH spent the whole of xmas day together. Which was lovely
I have got a question not sure if u can help me or where i can put this in the forums. I have been started on a mini pill and i started it the 1st day of my proper period ( I have a left pco) so i ovulated on my own for 1st period which i was worried about as sometimes don't for 3 months or so. I have now been bleeding for 14days but its only been light bleeding the last 7 days. TMI i only use 1 pad or tampax in 24hrs. Is this normal and has anyone else had this? When i took the combine pill for 6yrs i never had this problem it was 7days bleeding that was it.So wondering if its coz i have had a baby?? It does say in leaflet that it can course irregular light bleeding but i haven't taken a pill continuously b4 like this 1. It says with the light bleeding the pill still works!! Im confused about it all. Sorry bout long post xx
Posted: Sun Jan 15, 2012 9:53 pm
Post subject:
hi ladies not been on for ages been so busy hope everyone is ok even though some are having afew probs, kieran is now 7weeks week ago he was 10lbs 6ozs and has grown 3cms lol still in new baby clothes think he refuses to grow lol, we have bedtime routine thats going well except the odd night its bath at 8 then has a feed and off to bed he self soothes and i wake him at 12 for his last feed he then sleeps till 6 - 6.30ish from about 5weeks since we have got his colic sorted hes very clever and bables loads copys people to and likes to hold his arms up and shouts ug think its hug lol xx


text:
The Department of Music is accredited by the National Association of Schools of Music (NASM).
IPFW Wind Ensemble to perform in Carnegie Hall - News-Sentinel
Dr. Hamilton Tescarollo Named Music Teacher of the Year - WBOI
Kevin Eubanks Reflects on Music - arts IN focus, WFWA
Kevin Eubanks Masterclass at IPFW - Journal Gazette
Kevin Eubanks Starts the Day at Conference for Youth - WANE-TV
Carmina Burana at IPFW - WBOI
Monster Piano Concert Strikes a Chord - WBOI
The arts meet many basic human needs: aesthetic appreciation of sound and beautiful objects; expression of artistic feelings and emotions which prompt recognition of inner truths; sharing of accomplishments with others; the joy of discovery; satisfaction in achievement resulting from challenging and disciplined work.
Another basic human need is earning a livelihood. People possessing talent and creative ability are more fortunate than most - they have the option of developing their talents and pursuing careers they will enjoy and that will benefit others. While "art for art's sake" is an important philosophy in the College of Visual and Performing Arts, so is the opportunity to make a good living through one's talents and love of the arts.
When you review the following guides to career in the arts, you will realize that there are many career options available to creative musicians who are following their dream. We hope this information will be helpful as you consider possible careers in the arts and your preparation to contribute to society through your art.


text:
Vayots Dzor
- Home
- /
- Our Imports
- /
- Armenia
- / Vayots Dzor
- /
- Yeghegnadzor
The name of the region means "the valley of canes" in the Armenian language. During Joseph Stalin's time, the city was renamed after Soviet politician Anastas Mikoyan.
Surrounded by dramatic snow-capped mountains, the region of Yeghegnadzor averages 4,600 feet above sea level is recognized as the oldest wine region in the world with the ancient 6,100 year old winery unearthed just recently. The identity of the ancient Armenian wine-makers remains a mystery, but the scientists said they believed the press was used by predecessors of the Kura-Axes people, an early Transcaucasian group. Yeghegnadzor is Armenia's quintessential grape growing region for wines of elegance.
Long dry summers, with remarkably vivid sunlight and high daytime temperatures contrast with cool nights encouraging a lengthy growing season and pushing harvest to the end of October. The rocky soils, rich in limestone, help maintain moisture for the vines during the intense summer heat while the slow ripening ensures the development of natural sugars which balance the fruit's characteristic acidity.


text:
Knott County officials say they are almost back on track with their water supply, but they don't want bad weather to cause any more delays and Wednesday they implemented their own backup plan.
National Guardsmen have been in Knott County since water ran out.
They've been filtering a supply from a creek for nearly two weeks.
"Last time it rained we had to shut down for 24 hours because of the sediment in the water," Sargeant 1st Class Mar Metcalfe said.
They don't want to shut down again because the main tank is already back up to 26 feet.
Emergency officials came up with a backup plan using kids swimming pools.
"We're expecting some rain here on Saturday and that's going to muddy the water so basically what we're going is setting up a sediment basin," Metcalfe said.
"Basically, going from pool to pool until it should be clear enough until we can pump rain or shine," Judge Executive Randy Thompson said.
Water pumped into the pools will be processed so all sediment drains to the bottom...
The pool system might even get them ahead of schedule and officials say the supply can't fill up fast enough.
"When we can get the tanks fulll, the 3 Hindman wells that are dry or depleting, it should give us a chance to test those wells and see what the problem is," Judge Thompson said.
Thompson says the guardsmen will stay in Knott County for at least six more weeks and even though everyone should have running water in their homes, officials urge all residents to conserve.
Judge Executive Randy Thompson says these are only temporary solutions, but he says a long term solution is underway.
He says Knott County was just approved to begin construction on a water treatment plant and that's scheduled to be complete by September 2008.


text:
Game of Thrones is a site for the HBO-series based on George R.R. Martin's A Song of Ice and Fire.
New to the series? Read our spoiler-free review of A Game of Thrones.
Read our Privacy Policy.
HBO has been keeping busy with the HBO Store, adding new shirts, jewelry, steins, and more in the last month. We've compiled most of these at our store page (which benefits the continued maintenance and operation of Westeros.org), but two new items have cropped up that might be interest. First, there's an awesome new shirt featuring Needle and the text, "Stick Them With the Pointy End" (that's going to be popular!), and a poster map featuring the Seven Kingdoms and a bit of the coastline of Essos.
The Westeros network consists of several different sites, including a forum and a wiki, for all your A Song of Ice and Fire needs.


text:
Definición de pacemaker en inglés:
1A person or animal who sets the pace at the beginning of a race, sometimes in order to help a runner break a record: he acted as a pacemaker for Bannister when he broke the four-minute mile
Más ejemplos en oraciones
- That is some record for a horse used primarily in those races as a pacemaker.
- The pair was among seven for the 2,400-meter race, including both their respective pacemakers, Diyapour and High Action.
- He and Chris Chataway were the pacemakers as Bannister became the first man to break the four-minute barrier for the mile.
1.1A person who sets standards of achievement for others: unbeaten Rangers are the surprise pacemakers
Más ejemplos en oraciones
- Even though the automobile industry had also remained the pacemaker when it came to wages and working standards for its employees, it was not without its periods of labor turbulence - nor was it lacking in the desire to find workable and satisfactory solutions to labor problems.
- This is a practice called 'speeding up the line,' for every man down the line must keep up with the pacemaker's pace or he'll be thrown out for another worker.
2A device for stimulating the heart muscle and regulating its contractions.
Oraciones de ejemplo
- The most common forms of heart failure are treated with drugs and electrical devices such as pacemakers and implanted defibrillators, but if symptoms continue to worsen, other therapies are needed.
- For the medical device industry, only ads for risky devices such as pacemakers or artificial hearts must disclose negative side effects.
- Medical devices such as cardiac pacemakers, cochlear implants, and bone growth stimulators are valuable tools in the treatment of patients with multiple medical needs.
2.1The part of the heart muscle (the sino-atrial node) which normally regulates contractions.
Oraciones de ejemplo
- This node is called the pacemaker of the heart because it sets the rate of the heartbeat and causes the rest of the heart to contract in its rhythm.
- The sinus node is a natural pacemaker in your heart that helps your heart beat steadily.
- Sinus dysrhythmia refers to a malfunction of the sinus node, the heart's natural pacemaker.
2.2The part of an organ or of the body which controls rhythmic physiological activity: the brain's circadian pacemaker which regulates our 'biological clock'
Más ejemplos en oraciones
- For this reason, the researchers decided to examine the output of the body's internal clock, called the circadian pacemaker.
- Escape rhythms are the result of spontaneous activity from a subsidiary pacemaker, located in the atria, atrioventricular junction, or ventricles.
- In 1998 the journal Science published a report that indicated that light exposure to the back of the knee may reset the human circadian pacemaker.
pacemaking adjetivo& sustantivo
- Oraciones de ejemplo
- Going into this game two points adrift of the pacemaking Potters, the Saints pulled out all the stops to win in devastating style.
- The Saul side now occupy second spot, one point behind pacemaking Round House with a host of teams lining up behind them.
- At the moment they trail pacemaking Comber Rec by six points, but have two games in hand.
Palabras que riman con pacemakerlacemaker
For editors and proofreaders
Saltos de línea: pace|maker
Definición de pacemaker en:
¿Qué te llama la atención de esta palabra o frase?
Los comentarios que no respeten nuestras Normas comunitarias podrían ser moderados o eliminados.
Muy popular en Reino Unido
Muy popular en Australia
= de moda


text:
Growing pain---
Kansas has dropped three of four games now, including their only two road games back to back. I'd love to have twenty-four turnovers to decide between at Starbucks every morning, but they're quite a bit less palatable on the basketball court and the3 'Hawks couldn't overcome them last night at Florida. That KU was even in the game was testimony to Andrew Wiggins and some typically tough defense, although Florida's lack of hoops IQ didn't hurt.
Never mind that the Gators had problems closing the game at the line where they were woeful, but, with the lead in the last two minutes, they fouled three times to allow KU the opportunity to score with the clock stopped and once a Gator actually forgot (or maybe he just didn't know) that you could move along the baseline after a made bucket. Florida managed to hang on in spite of itself. As for KU….well, they come home for tough games against New Mexico, Georgetown and San Diego State before the start of conference play. The Big 12 opens with a game at one Oklahoma, before a rivalry game with K-State—then it's nationally ranked Iowa State on the road, followed by top ten Oklahoma State and one loss Baylor at home. The bext month and a half are fraught with peril.
As for the 'Cats---
K State had to rally to beat a 3-6 South Dakota at home last night, but they did win their fourth straight including a good home win against Ole Miss. The 'Cats are more of a work in progress than KU, which is bolstered by its talent. Not to say KSU doesn't have talent, it's just going to take longer to see it come to fruition. Still, the 'Cats are 6-3—just like the 'Hawks…ok, not exactly like them…but you get my point.
Mack attack---
The sharks are circling Mack Brown, who continues to deny that he's made a decision to step down at Texas. That may be true, but one has to think that the decision has probably been made for him. Texas has been very average since going to the National Championship game in 2009 and one thing Texans can't stomach…is being average. Actually, it's worse than that---since that title game nearly five years ago---Texas only has the fifth highest winning percentage among division one programs in the Lone Star State. Ouch.
The big question is—who will new Athletic Director Steve Patterson hire? Or, rather, who will the power brokers in the Board of Regents direct him to hire? Remember, this is Texas—I would be surprised if they don't make a serious overture to Nick Saban at Alabama. Sure, he's 62 years old and his legacy is colored Crimson, but he has a transient nature (since 1999: Michigan State, LSU, Miami Dolphins and Alabama) and seems drawn to new challenges. If it's not Saban, would they go after Art Briles, who just inked a long term extension at Baylor? I've hear some Texas complaints (really) that Briles isn't the kind of 'coat and tie' guy they like to have in Austin. Heck, a guy wearing a leisure suit looks pretty good when he's in the top 5 of the BCS.
Swing and miss---
Are the Royals done trying to improve the lineup after Carlos Beltron eschewed nostalgia for a career ending trip to the Bronx? With the acquisition of leadoff hitter Norachicka Aoki from Milwaukee they figure to drop Alex Gordon into the five hole, hitting behind Eric Hosmer and Billy Butler…not exactly Murderers Row—maybe they'll be Manslaugter Alley.


text:
Simon Rec Facilities
The Department of Campus Recreation offers outstanding recreational facilities. Below is a basic list of amenities along with a facility floor plan of the Simon Recreation Center. In addition to drop-in recreational opportunities, scheduled recreational programs and events are available. If you are interested in reserving space for an event, please fill out our facility scheduling request form. Requests must be received at least 10 business days before the event and are subject to the department's facility scheduling policy.
Upper Level
Administrative Offices
Fitness Center
Track 7.5 laps per mile
Multipurpose/Dance Room
Main Level
Member Services
Locker Rooms with Saunas
Indoor Pool
6 Indoor Gymnasium Courts
4 Racquetball/Handball Courts
1 Squash Court
Lower Level
Juice Bar and Lounge
Bouldering Wall
Fitness Center
Locker Rooms
Multipurpose Room 1 & 2
Spinning Studio
Mind/Body Room
Wellness Suite
Outdoors (SLU Ruba)
2 Outdoor Pools
Sand Volleyball
Sunbathing Area


text:
Consumer & Market Insight Manager – FMCG Power Brand
- Recruiter
- Tarsh Lazare Marketing Recruitment
- Location
- Berkshire / London (West), London (Greater)
- Salary
- £52K-£63K Package inc Excellent Bonus & Benefits
- Posted
- 13 Jun 2014
- Closes
- 13 Jul 2014
- Ref
- Business Type
- Agency, In-house / Client-side
- Specialism
- Research
- Contract Type
- Permanent
- Hours
- Full Time
Consumer & Market Insight Manager – FMCG Power Brand
£52K-£63K Package inc Excellent Bonus & Benefits
West of London
Superb research & insight role with a leading multinational FMCG business with a host of high-profile brands. Working with brand marketing and commercial teams across the European region, this is a key role requiring first class ad-hoc and continuous consumer research skills. You'll develop the consumer and market insights program for a major brand across the region, providing in-depth consumer understanding to support and guide decision making on NPD/innovation strategy, brand equity, category management & trade issues, shopper insights, advertising and packaging. This is an excellent opportunity to join a major FMCG business with a huge commitment to building its brands via innovation and big budget A&P activity.
Responsibilities will include:
* Reviewing business objectives with the Brand Director and Trade Marketing team to develop, manage and execute research plans to best support innovation / go-to-market strategy
* Developing a comprehensive understanding of the Brand Communication objectives and using research models to evaluate the effectiveness of the Brand communications
* Providing independent in-depth consumer journey insights across the region that will support brand strategy and NPD & EPD projects.
* Building strong relationships with Global and Area CMI and analytical teams to leverage and contribute to the insights and learning's and development of CMI best practice.
* Ensuring all market dynamics data for the brand across the region is reliable and actionable and cover all RB and competitor brands; strong focus and involvement in managing the business and NPD pipeline
Our Ideal Candidate
Proven experience in a fast-paced and busy FMCG business is key for this challenging role, almost certainly with a robust agency-side training too. You will have been exposed to a wide range of research methodologies and enjoy seeking out new ways to get under the consumer's skin. Your experience will span product/concept testing including volumetrics, brand equity measurement and advertising tests & tracking working in conjunction with local management teams and the global insight team. Ideally you will have worked on multi-country projects and will be happy to travel overseas regularly. Strong commercial nous is key with exceptional influencing and communication skills.
Company Profile
A first-class, blue-chip global FMCG business with a significant portfolio of well-known and trusted brands in the global household, health and personal care sectors, trading in countries across the world. This company invests very heavily in NPD and massive ATL spends and has seen huge growth over recent years. The culture is energetic, entrepreneurial and highly results-driven with opportunities to make a substantial contribution to the business. This is a business in which you'll find plenty of drive and energy, and a direct and open style; a business where you'll be given the freedom to make your mark throughout your career.
Tarsh Lazare is committed to finding the right roles for talented candidates. We are a leading name in marketing recruitment with extensive recruitment experience working with brand management, communications, category management and insight/research specialists. If you would like to discuss this role, or any other roles that might be suitable, please e-mail or call one of the team now on 020 7849 6875
If you don't feel this role is quite right for you, but think you know someone who might be suitable, do please pass this advert on. We do offer a recommend-a-friend scheme and you could receive £200 in John Lewis vouchers should you recommended someone who is offered and accepts the role.


text:
These powerful plugins will allow your visitors to rate or vote upon anything on your blog. Very useful plugins.
Archives Wordpress Feed
WordPress Themes, Plugins and Tutorials
Powering over 25% of all sites on the web, it's safe to say that WordPress is the most popular CMS (Content Management System) for creating websites. Written in PHP, open-source, versatile, powerful and highly extendable. It is the preferred system for web designers and developers, and because it's so easy to use, it's very popular with beginners as well.
Here you will find carefully curated collections of powerful and free WordPress themes and a huge selection of free WordPress plugins that will allow you to add even more functionality to the CMS.
20 Social Bookmaking Plugins for WordPress
There are many, many Social Bookmarking options available for Wordpress, I have tried to sift through as many as I could to give you the best 20.
My favorite is Sociable, which I use on this site. Thats not to say it is the best, the idea is to find the plugin that best fits into the theme and style of your site.
10 WordPress Plugins for Flickr
Flickr, like twitter and YouTube seems to be everywhere nowadays. And just to make things that little bit easier here are 10 WP Plugins to integrate Flickr directly into your blog.
18 WordPress Plugins to add Professionalism to your Blog
Is it time to take your Wordpress Blog to the next level? Has the time come to take your blog up to the level of professionalism that all the top blogs use?
Here are some easy to use but powerful Wordpress plugins that will help you on your way, they range from Newsletters, RSS, Legalities, creating Directories, User Login… I hope they help.
30 Essential and Advanced WordPress Plugins
These are a list of advanced WP plugins that I have used and tested, and have proven to be indispensable. They are not listed by any kind of rank. 1….
10 Security Plugins for WordPress
With every site you build there are going to be security risks and issues, there is no way around this, it is going to happen. All we can do is…
30 Free Resources for WordPress Photoblogging and Image Galleries
If you are wanting to create a photoblog, or even just to display your family and personal images on your blog you will find solutions here. From the intricate to…
The Best Cheat Sheets for Web Designers and Developers
It is pretty hard to remember all the Internet Scripting Languages, luckily we have Cheat Sheets. Below are all the best Cheat Sheets for (almost) every web script available, or…
Free WordPress Theme (The Dark Hut)
This theme has been a change for me, I went for a darker look. I kept to my usual style of using a minimal amount of images, in this case…
The Azure Hut (WordPress Theme)
For this theme I wanted to break away from my usual clean style and come up with something completely different. The idea was to have a split page, with clearly…


text:
Product prices and availability are accurate as of the date/time indicated and are subject to change. Any price and availability information displayed on Shoebuy.com at the time of purchase will apply to the purchase of this product.
Get it today!Shop Now
OrAdd to Wish List
This yoga pant is made from a moisture wicking blend of nylon and Lycra and has a covered stretch elastic waistband, a gusseted crotch, padded knees for comfort while in poses, and a reflective copper logo.. Price: $54.95
© Copyright 2016 - Christmas.com. All rights reserved and protected by Christmas Spirit


text: Fabrice HOSS REPORTERS Canada: A Chinese Eldorado? Canada is a vast, fertile and sparsely populated country, a fact not lost on Chinese immigrants. Many of them are now buying up land and becoming farmers. Our reporter Fabrice… Read more REPORTERS Quebec: the Maple Leaf Mafia For the past few months, the French-speaking Canadian province of Quebec has been gripped by a tale of corruption involving public officials and the construction industry. The… Read more


text:
Definition of data terminal in English:
data terminal
A terminal at which a person can enter data into a computer-based system or receive data from one.
Example sentences
- Even without the bonus of being able to sell more servers and systems, for the likes of HP and Compaq, the mobile data terminal market represents a huge opportunity.
- Image data is transmitted by a steered, 360 degree J-band video data link to the ground data terminal and then by cable to the control station up to 1 km away.
- This capability is a must because data terminal equipment such as laptops, small digital message terminals, digital cameras and other DTE exist in many cases down to the soldier level in our current and future force.
For editors and proofreaders
Syllabification: da·ta ter·mi·nal
Definition of data terminal in:
What do you find interesting about this word or phrase?
Comments that don't adhere to our Community Guidelines may be moderated or removed.
= trending


text:
Community Impact Cabinet
The Community Impact Cabinet oversees United Way's funding and allocation process. They provide both funding recommendations and process regulations to the Board of Directors concerning United Way Oakville's community involvement, investment and long-term strategies that impact the community.
2014-2015 Members
|Peter McAdam
Community Impact Cabinet Chair
Felix Global Corp.
|Wai-Man Kwan
Associate Director Regulatory Affairs,
Gilead Sciences
|Ken Auden
Community Volunteer
|Lisa E. Piccolo
Vice-President, Advancement & External Relations,
Sheridan College
|Lee-Ann Charszewski
Agency Funding Committee Chair
Senior Consultant
Health Systems Group
|Angela Rea-Mahoney
Project Director
Trillium Health Partners
Get Involved!
Members must be team players, with strong analytical skills and exhibit creative-thinking and knowledge of the human and social services sector. CIC members are expected to attend monthly meetings and UWO events.
Contact Anne Smith, Director of Community Impact for more information:
Email Anne or call (905) 845-5571 ext. 230.


text:
Focus Stocks
Close to the 50 Day Moving Average: Baxter International
Published on Friday, 13 April 2012 06:24 Written by TradersHuddle Wire
New York, April 13th (TradersHuddle.com) - Baxter International, Inc. (NYSE:BAX) closed the trading day at $58.71, near its 50 day moving average that is set at $58.29. Baxter's price action is just above this important support level, providing a trading opportunity.
Baxter International Inc. (NYSE:BAX) develops, manufactures, and markets products and technologies related to hemophilia, immune disorders, infectious diseases, kidney disease, trauma and other chronic medical conditions. The healthcare products are used by hospitals, kidney dialysis centers, nursing homes, rehabilitation centers, doctors' offices, and research laboratories.
The peaks and troughs algorithm shows calculated support at $47.55 and calculated resistance at $57.15. These levels should also be evaluated when planning trades, as they provide an insight into the latest price action.
Traders wanting to establish a position on Baxter International should look for evidence of buying near the 50 day moving average, and open this position as close as possible to this important level. Also, they need to consider the latest range defined by the peaks and troughs algorithm for insights on other key levels that might impact an upside or downside move.
Related Articles
- AT&T And America Movil To Provide Deeper National Reach For Advanced Enterprise Services Across Latin America
- AT&T 4G LTE Available In Willimantic
- AT&T 4G LTE Available In Torrington
- AT&T And The University Of Kansas Team Up To Enhance Wireless Coverage On Lawrence Campus
- AT&T 4G LTE Available In Fargo
- AT&T 4G LTE Available In Amarillo
- Benefitfocus Announces Pricing of Initial Public Offering
- Trends of China Gear Industry 2013 Analysis & Reviewed in New Research Report at RnRMarketResearch.com
- Product Launch Formula 4.0 Bonuses Total $5000 at BrianHanson.com
- Datex Presents Motorola Solutions Webinar "Is It 'Smart' to Use Smartphones for the Enterprise?"
Related Partner Headlines
TradersHuddle Search
Stock Search:
Site Search:
Technical Scans
Recent Trading Ideas
Latest Partner Headlines