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Creamy Roasted Sweet Potato Soupby theblendergirl I am constantly overwhelmed by the surprising depth of flavor of this ..
Vegan Cream of Spinach Soupby theblendergirl The best thing about this soup? It takes less than half an hour from c..
Raw Vegan Avocado Gazpachoby theblendergirl This quick easy Summer cooler is like "liquid guacamole" that kick..
Turkey and Stuffing Rollsby scottw Stuffed with Thanksgiving turkey, cream cheese, and just the right sea..
Elbows and Broth aka 'I Don't Feel Good' Soupby theadkchick For as long as I can remember when I was sick my mom and grandmother w..
Cheeseburger Soupby onesassy I have read about this soup somewhere along my recipe board travels an..
Butternut Squash Soupby BrownEyedBaker A fabulous butternut squash soup that gets a punch of flavor from dark..
Tuna Noodle Casserole w/ Cheese Crumb Toppingby GourmetMommy This is a childhood favorite of mine..I make it just like my Gram and ..
Cheese Strawsby scottw Crispy and fun to eat, these skinny little morsels are a taste temptin..
SMOKY SOUTHWEST CHICKEN AND WILD RICE SOUPby Canned_Food_Fan Add some fire to a cold day with a smoky, spicy Southwest-style soup. ..
Hearty Tomato Soup with Lemon and Rosemaryby jmgallo From Giada De Laurentiis' Giada's Kitchen
Rich, Creamy Chicken and Noodle Soupby imstuffed Simple, tasty and all around very satisfying soup. This was adapted fr..
Thai Death by Soupby thegoddessmelissa That's what my friend that makes this calls it. I don't know what it'..


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Make this your new stay-young mantra: great skin starts at the sink. Look for a face wash with antioxidants to fight off damaging free radicals, a hydrator to keep skin from feeling stripped, and a chemical exfoliant like alpha hydroxy acid to slough away dead skin. Yes To Blueberries Age Refresh Smoothing Daily Cleanser, $10, has blueberries, coconut oil and apple to cover all three musts.
Courtesy of Yes To
Sometimes, all you need for smoother-looking skin is patience and a dose of the good stuff ... retinol! Derms have called this vitamin A derivative a magic wand for wrinkles, since it helps prevent collagen breakdown. As in, it'll help prevent wrinkles and repair fine lines you have. Look for a gentle formula, like Garnier's $17.99 Ultra-Lift 2-In-1 Wrinkle Reducer Serum & Moisturizer For Wrinkles + Firming, $17.99.
Courtesy of Garnier
Sadly wrinkles aren't the only enemy. Dark spots that pop up because of sun exposure, hormones or irritation can age you—big time. To combat, look for a cream like Vichy Laboratories ProEVEN Daily Dark Spot Corrector, $45, which promises to brighten with vitamin C, an antioxidant that helps skin repair itself, and exfoliate with chemical (not gritty) ingredients like lipohydroxy acid.
Courtesy of Vichy Laboratoires
If you do nothing else for your skin, use broad-spectrum sunscreen every single day. Seriously. UVA rays, which penetrate more deeply into the skin, can sneak through windows. If extra lotion is not your thing, try using a teaspoon daily of a sunscreen that acts as a primer. L'Oréal Revitalift Miracle Blur with SPF 30, $19.99; leaves skin matte, blurs fine lines and can be worn under makeup.
Courtesy of L'Oréal
You know how people pay zillions of dollars to get a peel at the derm? Unless you've got serious signes of aging, don't bother. If you just have fine lines or a little dullness, exfoliate weekly with an at-home glycolic peel to ditch dead cells and leave healthy skin front and center. An awesome option: Boots No7 Glycolic Peel Kit, $25.
Courtesy of Boots
Believe it or not, some of your fine lines (especially the ones that feel like they appeared overnight) could just be a sign of parched skin. Before you hit the pillow, load up on a rich night cream that promises to help skin hold on to its own moisture with ingredients like clary sage. Find it in Burt's Bees Intense Hydration Night Cream, $18, which absorbs in seconds so your skin—not your pillow—gets all the benefits.
Courtesy of Burt's Bees
Not down for spending hundreds to ditch the first signs of crow's feet? Get instant results without the instant debt, with an eye cream such as Physicians Formula SkinConcern Anti Aging Expression Line Freeze Serum, $21.95. It's got a combo of ingredients that instantly tightens and lifts for four hours, as well as peptides and alpha hydroxy acids that prevent and repair the wrinkles you have. It works around your mouth too!
Courtesy of Physicians Formula
Get this: yellow- or gray-looking teeth add years to your look, even if your skin is flawless. But there's no reason to make an $400 appointment with your dentist (then squirm every time you drink something cold for weeks after). Crest 3D White 2-Hour Express Whitestrips, $50, use a peroxide-infused gel to whiten noticeably in two hours. Do it once every three months before you brush at night.
Courtesy of Crest
Since skin on the back of your hands is relatively thin and constantly exposed to UVA and UVB rays, it takes a beating. Use a hand cream with SPF to prevent aging, as well as retinol to repair. Retinol Anti-Aging Hand Cream with SPF 12, $12.99, hydrates without leaving hands clammy.
Courtesy of Retinol
You know that puffy-lipped look that screams "I spend too much money at the derm!"? You don't want that. What you do want is smooth, well-hydrated, wrinkle free lips ... for $3. Blistex Deep Renewal Lip Protectant, SPF 15, $2.99, has hyaluronic filling spheres (aka little balls of moisture) that fill in wrinkles, making lips look fuller, as well as coenzyme Q-10, a flake-erasing lip hydrator.
Courtesy of Blistex
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text: Our Rocker Girl Party Supplies feature rock star images with a girly twist. The words Rock Star along with a purple guitar and a pink heart with wings and a tiara above it are displayed on each piece. Let our Rocker Girl Party Supplies help you make your next birthday party one big rock star party! Add unique decorations and favors for special personalized touches!


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Golden (AP) A 200-ton rock slide spilled onto a mountain highway near Golden this afternoon, injuring a truck driver and closing the roadway. All lanes of U.S. 6 were shut down through Clear Creek Canyon after about 200 tons of rock slid onto the highway about ten miles west of Golden.
Colorado Department of Transportation Spokesman Gene Town says two tractor-trailers were involved in the slide. One of the drivers was injured but his condition wasn't immediately available.
Town says the debris spans 150 feet on the highway and could be up to 30 feet high. Heavy equipment is working to clear to highway, but Town says the highway could remain closed until Wednesday.
The slide was reported around 11:30 Tuesday morning. Motorists are being diverted to Interstate 70.
(Copyright 2005 by the Associated Press. All rights reserved.)
apnp 06-21-05 1309mdt<
© KKCO NBC 11 News - All Rights Reserved


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Enter your stay dates and any discounts you qualify for to see Roy, UT rates found only on HotelPlanner!
Find accommodations in Roy with the hotel list provided below. Find cheap and/or discounted hotel rates in or near Roy, UT for your corporate or personal leisure travel. We list the best Roy Utah hotel rooms. Review the Roy hotel list below to find the perfect lodging. We also have a map of the Roy hotels.
The Roy center point is approximately 2 miles southwest of Ogden Hinckley Airport and 5 miles southwest of Historic Union Station.
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The comedian and author's best selling children's novel will come to life in an open air theatre show in Caversham
Here's all you need to know about the children's festival taking place this May
Fancy starring in the world premiere of this story by David Walliams? Here's all you need to know about how to audition
Waterstones Reading Broad Street and Oracle stores have joined the national wide campaign, Buy Books forSyria, with the goal to help raise one million pounds for Oxfam's Syria Crisis Appeal.
getreading's Hilary Scott has been a judge on Has Reading Got Talent? from the start. Here's her tips and advice for performers
Jon Clegg, who starred as Simple Simon in Jack and the Beanstalk at The Hexagon last December, and will be returning to star in Cinderella this year, will compete in the final this Saturday.
Impressionist Jon Clegg failed to make it through to the final but could a wild card vote see him back in the game?
Jon Clegg, who is playing Buttons in Cinderella at The Hexagon this winter, had the judges in stitches with his hilarious impressions
Were you a fan of Muffin the Mule? Thunderbirds or Thundercats? My Little Pony? Blue Peter? Let us know in our new survey
Muppets and Lady Gaga, John Bishop, Strictly Come Dancing, Dr Who and Downtown Abbey will make our viewing merry and bright
A teenager has raised more than £3,000 to help fulfil his dream of coaching football to children in Rwanda.
Armour: Georges and Anne are retired, cultivated Parisian musicians in their eighties. When Anne suffers a paralysing stroke the couple's touching, substantial bond of love is severely tested.
Celebrities with Reading connections are about to part company after spending much of 2012 together.
The weather outside is frightful so put on your slippers, grab a mince pie and settle down for some fantastic festive telly.
A film adaptation of one of Dickens' finest novels with a stellar cast is about to put a Berkshire stately home on the silver screen.
Britain's favourite dog Pudsey is coming to Reading to sign copies of his autobidography.
Every week our square-eyed reporters take a look at what's on TV – the highlights and the lowlights – and pick what they think you should watch or avoid.
The talented daughter of a music producer behind Buzzcocks and The Stranglers could soon see her own name up in lights after she was chosen to perform with the National Youth Theatre.
Room 101: Extra Storage, BBC, Sunday, 11.10pm: The popular comedy panel show now comes in a bigger 40-minute package, with Frank Skinner as host.
Sport Relief, BBC One and BBC Two, Friday, from 7pm.
With a name like Sport Relief you'd expect a bit of a marathon show and that's exactly what the producers of this year's fundraiser have organised.
Every week our square-eyed reporters take a look at what's on TV – the highlights and the lowlights – and pick what they think you should watch or avoid.
You may not be able to manage a whopping David Walliams-style effort for Sport Relief but a gentler option is on offer in Caversham.
The month started with the tragic news that Reading Royal Marine Sergeant Barry 'Baz' Weston had been killed in Afghanistan.
Rob Brydon is one of our funniest and best-loved comedians. He has starred in some of the most lauded and adored comedies of the last decade, including Marion and Geoff, The Keith Barret Show, Gavin and Stacey, The Trip, Human Remains and Would I Lie to You? He has also fronted his own TV chat show, the imaginatively named Rob Brydon Show.
Funny man David Walliams has made a pit-stop in Sonning this morning as he reaches the half-way point of his mammoth swimming challenge along the Thames.
Reading Post chief reporter Linda Fort reads the lunchtime headlines for Friday 9 September.
A little Briton with a big heart – and strong stomach – reached Reading last night on his mammoth Sport Relief challenge to swim the Thames.
One of the country's top comedians is due to be swimming through the borough this week as part of a challenge to raise thousands for Sport Relief.
Little Britain star David Walliams was met by large cheering crowds as he swam through Goring this morning.
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J. Dev. Biol. 2013, 1(2), 112-125; doi:10.3390/jdb1020112
Epicardium Formation as a Sensor in Toxicology
Department of Pharmaceutical Sciences, University of Wisconsin, 777 Highland Ave, Madison, WI 53705, USA
* Author to whom correspondence should be addressed.
Received: 27 May 2013 / Revised: 12 July 2013 / Accepted: 15 July 2013 / Published: 24 July 2013
(This article belongs to the Special Issue Epicardial Development and Cardiovascular Disease)
View Full-Text | Download PDF [184 KB, uploaded 24 July 2013] |
AbstractZebrafish (Danio rerio) are an excellent vertebrate model for studying heart development, regeneration and cardiotoxicity. Zebrafish embryos exposed during the temporal window of epicardium development to the aryl hydrocarbon receptor (AHR) agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exhibit severe heart malformations. TCDD exposure prevents both proepicardial organ (PE) and epicardium development. Exposure later in development, after the epicardium has formed, does not produce cardiac toxicity. It is not until the adult zebrafish heart is stimulated to regenerate does TCDD again cause detrimental effects. TCDD exposure prior to ventricular resection prevents cardiac regeneration. It is likely that TCDD-induced inhibition of epicardium development and cardiac regeneration occur via a common mechanism. Here, we describe experiments that focus on the epicardium as a target and sensor of zebrafish heart toxicity.
Keywords: epicardium; proepicardium; TCDD; AHR; heart regeneration
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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MDPI and ACS Style
Hofsteen, P.; Plavicki, J.; Peterson, R.E.; Heideman, W. Epicardium Formation as a Sensor in Toxicology. J. Dev. Biol. 2013, 1, 112-125.View more citation formats
AMA Style
Hofsteen P, Plavicki J, Peterson RE, Heideman W. Epicardium Formation as a Sensor in Toxicology. Journal of Developmental Biology. 2013; 1(2):112-125.Chicago/Turabian Style
Hofsteen, Peter; Plavicki, Jessica; Peterson, Richard E.; Heideman, Warren. 2013. "Epicardium Formation as a Sensor in Toxicology." J. Dev. Biol. 1, no. 2: 112-125.
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