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Rhabdomyolysis (cont.)
Siamak N. Nabili, MD, MPH
Dr. Nabili received his undergraduate degree from the University of California, San Diego (UCSD), majoring in chemistry and biochemistry. He then completed his graduate degree at the University of California, Los Angeles (UCLA). His graduate training included a specialized fellowship in public health where his research focused on environmental health and health-care delivery and management.
William C. Shiel Jr., MD, FACP, FACR
Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.
In this Article
- Rhabdomyolysis facts
- What is rhabdomyolysis?
- What causes rhabdomyolysis?
- What are the symptoms of rhabdomyolysis?
- What should I do if I think I have rhabdomyolysis?
- How is rhabdomyolysis diagnosed?
- What are the complications of rhabdomyolysis?
- How is rhabdomyolysis treated?
- What is the prognosis for rhabdomyolysis?
What are the symptoms of rhabdomyolysis?
Rhabdomyolysis may not cause any symptoms at all. Muscle aches and pain (myalgia), stiffness, and muscle weakness can occur with rhabdomyolysis, and is especially common with severe muscle damage. Rhabdomyolysis may cause a darkening of the urine color. Myoglobin is released from the muscles when they break down and is excreted into the urine. This can cause a red or cola color of the urine.
What should I do if I think I have rhabdomyolysis?
If you have signs and symptoms suggestive of rhabdomyolysis, your doctor needs to be notified promptly. It is important to realize that these symptoms are not specific for rhabdomyolysis as they may be caused by other conditions.
How is rhabdomyolysis diagnosed?
Rhabdomyolysis is suggested by the history of recent and past events and the physical examination. It is confirmed by blood and urine testing. An important part of diagnosing rhabdomyolysis is a comprehensive medical history and physical examination.
The medical history may include questions about any medication use, drug and alcohol use, other medical conditions, any trauma or accident, etc. Blood tests include a complete blood count (CBC), a metabolic panel, muscle enzymes, and urinalysis.
The diagnosis of rhabdomyolysis is confirmed by detecting elevated muscle enzymes in blood, which include creatine phosphokinase (CPK), SGOT, SGPT, and LDH . The levels of these enzymes rise as the muscle is destroyed in rhabdomyolysis.
While the SGOT, SGPT, and LDH enzymes are found in muscles, they are more frequently associated with the liver. Therefore, elevations of SGOT and SGPT, without elevated CPK, are more typically indications of liver damage.
Of note, CPK is also in heart muscle (cardiac muscle) and brain. The laboratory is usually able to distinguish between the different components of this enzyme. For example, the fraction coming from skeletal muscle is referred to as CK-MM and the one from heart muscle is designated as CK-MB. There are small amounts of the CK-MB component in the skeletal muscle as well.
The levels of myoglobin can be elevated in blood and urine
Women's Health
Find out what women really need.


text:
SON - I am the son of not only Jamie and Janet Prokup but of my
spiritual Father who will guide me in the right direction.
CATHOLIC - being Catholic is not only my religion but a major part
of who I am.
PROPHET - I am a modern prophet of sorts willing, through the
written word, to talk about God to whomever wants to listen.
DISCIPLE - I will always do my best to spread the word of God
through my actions.
BELIEVER - I believe in the goodness of people and in this world
because ultimately I am a believer of God.

subset: commoncrawl


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- Today Cloudy through mid morning, then gradual clearing, with a high near 51. Southwest wind 6 to 15 mph becoming northwest in the afternoon.
- Tonight Mostly clear, with a low around 25. Northwest wind 5 to 9 mph becoming light and variable after midnight.
- Wednesday Mostly sunny, with a high near 48. Light east wind becoming southeast 5 to 10 mph in the morning.
- Wednesday Night A 50 percent chance of showers after midnight. Mostly cloudy, with a low around 38. South wind 8 to 10 mph.
- Thursday Showers likely before noon. Partly sunny, with a high near 49. South wind 7 to 9 mph becoming north in the afternoon. Chance of precipitation is 70%.
- Thursday Night Mostly clear, with a low around 28.
- Friday Sunny, with a high near 43.
- Friday Night Partly cloudy, with a low around 30.
Location, ST | website.com


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Are Macro Changes in Store for Microlending?
New financial tools and technologies are poised to change the way microfinance is practiced, says Suresh Sundaresan.
You open this new book, Microfinance: Emerging Trends and Challenges, by pointing out that the high end of the microfinance ladder has embraced a number of innovations, while the lowest rungs have continued to work largely the same way through the years. What is driving the difference between the high and low rungs?
At the lower end of the spectrum, there are mostly women borrowers, who participate mostly in group lending. The average loan size is fairly small. Big institutions are less interested, because to put together a portfolio of two or three million dollars with an average loan size of 150 dollars, you really need to have thousands of loans. It was not a scalable proposition until very recently.
In the current structure, borrowers still participate in group lending and village banking and are being primarily served by NGOs, which are driven by soft capital. NGOs don't worry about scaling up the same way banks or other largely profit-driven financial institutions do.
What does the future hold in terms of scalability?
There have been two big developments. One is innovation in information technology. The ability to deliver loans through mobile phones means that if a lender can deliver a thousand-dollar loan from point A to point B separated by thousands of miles, that lender can just as easily deliver a 20-dollar loan. The transaction cost is eliminated, so, suddenly there's the possibility of delivering loans through mobile phones into kiosks — very much like the system we have for delivering phone cards. That has already happened in the Philippines and has opened up the possibility for scalability for the lower end of spectrum.
The second innovation is happening with BRAC, the Bangladesh securitization project. It's a Grameen type of system — the loans are very small. Bangladesh is a small country, but it is waterlogged, with a lot of remote corners that are not well connected. BRAC manages by keeping meticulous loan records for every village. The data on loan performance for all these tiny loans were eventually computerized so that they could be aggregated into a fairly large portfolio. That portfolio was then securitized and assured a credit rating, and pension funds and others invested in it. So I think this and similar innovations in financial securitization and information technology hold big hope for scalability.
Given that the credit crisis has been largely driven by securitization and CDOs, that is not exactly comforting. Why should microfinance be any different?
It's true that these are precisely the strategies and instruments that are seen as the main culprits in the credit crisis. But in microfinance, for most of these borrowers, if they default or if they don't service the loans, the outside costs of borrowing will become much, much higher. So they are very incentivized to avoid default. They are responsible to their borrowing group, and their reputation is at stake because their entire village will know if they default.
Contrast that with subprime borrowers, who can walk away from their loan, which is a non-recourse loan; the bank can only take over a home (now worth less) but cannot come after personal accounts or other property. The repayment incentives for a microfinance borrower are much more severe, and so the underlying risk for securitized microfinance products is much more reasonable than what we've seen with mortgage securitizations and CDOs here.
Also, if mobile-phone technology lives up to its promise, securitization might become less important. A poor borrower in Chennai can take delivery of a loan from a lender in Delhi, hundreds of miles away; as long as her credit history is in the mobile-phone system, the credit history can transmitted to Mumbai or wherever she migrates for another job. She can find job opportunities and continue to service the loan, so it is not even necessary to aggregate these loans. We are still far away, but it could easily develop along these lines.
What political and regulatory roadblocks have delayed the expansion of microfinance innovations?
There were problems getting BRAC running. Politicians delayed the project for different reasons. First, infrastructure: the borrowers were dispersed throughout remote villages without computer records, and by the time the information was aggregated — well, it took forever to go to the credit-rating agencies to share the records, to verify that the borrowers were in good standing and so forth. We take that for granted here — we are able to get a decision in just a few weeks. But the basic infrastructure wasn't there.
Nationalized banks and rural branches, which tend to not do as good a job as NGOs when it comes to microlending, don't see the need to spend money to establish infrastructure for NGOs that would allow for improvements in microlending.
Second, the government's stance could be more helpful. One South Asian bureaucrat asked me why anyone would give microloans to one hundred or two hundred women when chances are only 20 or 30 of them are likely to be entrepreneurs. To his mind, the remaining women were not entrepreneurial and therefore wouldn't be able to do much with a loan. Now, this business model might not appear to be a very good one at first glance. But a loan might allow borrowers to buy something that morning, go to the local bazaar and sell them at a margin and by the evening they would have made certain amount of money for themselves. These women may not be highly skilled entrepreneurs, but for a hundred-rupee (two-dollar) loan you can't expect a very high level of entrepreneurial skill. The bureaucrats frame the question as if these women need to have a great deal of skill, but a high level of skill is not really required for the system to work.
Along the same lines, many BRAC investors balked at some of the less-than-standard ways that default and current loans were defined, even though the average default rate was extremely low. Why the resistance despite such impressive results?
A U.S. credit-card company might say if a particular credit-card user is delinquent for one month they might want to write off some part of that loan. But delinquency in microlending is often involuntary. Often, the local lenders know if a borrower is having some genuine problems and know that if she's given extra time she'll be able to pay the loan back. So they won't necessarily flag that as a problem loan.
But the credit-rating agencies (CRAs) won't necessarily take that position. The CRAs would see these delinquencies as a potential for future default and insolvency, forgetting that these borrowers have a great deal of interest in repaying because if they default there is huge community pressure on them. It is group borrowing; they have to go back and live in their village, neighbors will be watching them and there is great deal of pressure.
In fact, that social pressure is a great loan enforcement mechanism, but it has a social cost. Borrowers have committed suicides in some Indian villages, for example, after years of drought left them unable to repay loans. Is it really worth it to claim that there is a 98 percent payment rate when people for reasons well beyond their control end up defaulting on loans and eventually committing suicide?
Microfinance has been viewed, in its relatively short history, as more or less immune to recessions. Given that the credit crisis underlies the current recession — which is undeniably a global one — might that have a bigger effect on the field than past economic downturns?
There will be serious consequences in the sense that soft capital and soft loans that typically go to NGOs and to the poorest of the poor will probably suffer. But while there could be a dip in the aggregate money that flows into the sector over the next couple of years, in the long run, given the momentum that this field has experienced, I'm very optimistic.
But I also want to point out that while it's important to consider what microfinance can achieve, we sometimes focus on microfinance and forget that these families operate under very difficult circumstances. The technology they use is rudimentary — wood stoves, for example — and they live in unhealthy environments and lack access, in many cases, even to primary education.
Microfinance lending is properly viewed as part of an overall strategy in which efforts are made to improve primary education, especially for woman and children, healthcare and improving domestic tools used for day-to-day activities. Parallel work is being done in these dimensions, and at some point they will reach a critical mass where it may be possible to coordinate those efforts.
Suresh Sundaresan is the Chase Manhattan Bank Foundation Professor of Financial Institutions in the Finance and Economics Division at Columbia Business School.
M. Suresh Sundaresan
Suresh Sundaresan is the Chase Manhattan Bank Foundation Professor of Financial Institutions at Columbia University. He has published in the areas of Treasury auctions, bidding, default risk, habit formation, term structure of interest rates, asset pricing, investment theory, pension asset allocation, swaps, options, forwards, futures, fixed-income securities markets and risk management. His research papers have appeared in major journals such as the Journal of Finance...
Read the Research
M. Suresh Sundaresan
"Microfinance: Emerging Trends and Challenges"


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See who's on Silver Singles:
Easy going, down to earth, fun loving, caring, compassionate & loyal person. Love nature and all it has to offer. Have many interests a...
poeticfem is a 66yr-old single woman in Meridian, Idaho
Upbeat /happy /busy /good health/many interests. I love new experiences and new people. I volunteer in my community. I am patriotic an...
eternaloptomist is a 68yr-old single woman in Meridian, Idaho


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This is an excerpt from EERE Network News, a weekly electronic newsletter.
February 23, 2011
USDA Requests Renewable Energy Funds in FY 2012 Budget
Although President Obama's fiscal year (FY) 2012 proposed budget for the U.S. Department of Agriculture decreased to $23.9 billion from the $27 billion level in FY 2010, the budget still invests $6.5 billion to support renewable and clean energy. In particular, the Agriculture and Food Research Initiative is getting an increase of $8.2 million for a research initiative to develop high-quality, cost-effective feedstocks for biofuel production. And the Rural Business-Cooperative Services, which operates a renewable energy loan and grant program for the purchase of renewable energy systems and energy efficiency improvements, will see a combination of mandatory funding and grants for programs at about $57 million above the 2011 total.
The proposed USDA budget provides $6.1 billion for loans for electric programs, with $4 billion used for generation, transmission, and distribution of renewable energy. This sum is down from the estimated FY 2011 funding, but still provides Rural Utilities Services with extensive resources that can be used to purchase or construct peaking units in conjunction with an electric generating plant that produces electricity from solar, wind, or other intermittent source of energy. The loans also can support applicants seeking to switch from fossil fuels to renewable technologies. As further evidence of support for renewables, the Agricultural Research Service (ARS) would see an increase in allocations totaling $58.7 million to conduct research and maintain ARS laboratories to tackle critical issues, including improving the efficiency and reducing the cost for the conversion of agricultural products into bio-based products and biofuels. See USDA Secretary Vilsack's statement, the Office of Management and Budget fact sheet for the USDA, and the USDA budget summary , notably pages 3, 46–48, 96, and 102.


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How to Print Images from Photoshop Elements 11
Open a file in the Photo Editor and choose File→Print.
The Print dialog box that opens contains all the settings you need to print a file. When you want to manage color, print from the Photo Editor and not the Organizer.
Select the orientation of your print. You can choose either Portrait or Landscape. Select the proper orientation in the Page Setup dialog box.
Select your printer from the Select Printer drop-down menu. Set the print attributes. Select the number of copies, position, scaling, and output items you want.


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Bapineuzumab fails phase III
26.07.2012 - Pfizer and Johnson & Johnson report that Bapineuzumab failed the first of four phase III trials.
The monoclonal antibody Bapineuzumab could not outperform a placebo in moderating symptoms of mild-to-moderate Alzheimer's disease. Expectations on an intravenous formulation of the drug to help a group of patients sharing the so called ApoE4 (apolipoprotein E epsilon 4) genotype could not be fulfilled. Pfizer did not release details of the study's outcome, but a principal investigator in the trial, Reisa Sperling, told The New York Times that "there was absolutely no evidence at all of a clinical benefit of treatment on either of the primary measures." The antibody developed by the Irish company Elan and US company Pfizer is tested in a large-scale Alzheimer's Immunotherapy Program for its suitability for treating the most common form of dementia. Meanwhile Johnson & Johnson joined the team for a total of four clinical trials. 1100 patients participated in the trail, all of them carriers of the ApoE4 risk gene. It is possible that patients without this gene modification could gain more profit from the agent. A second study with this group will start in the following weeks, two others are still ongoing.
Bapineuzumab is the follow up agent of AN1792, a vaccine which also failed. AN1792 successfully stimulated the formation of antibodies against beta amyloid – a protein that can exert toxic effects in the brain and is believed to play a central role in the pathology of Alzheimer's disease – in animal studies. But in 2002, a phase II trial had to be stopped because of safety issues. Aseptic meningoencephalitis and leukoencephalopathy were diagnosed in 6 percent of the participants. Nevertheless, some hints were given that the vaccine achieved an effect. The same effects were expected for Bapineuzumab, of course without the negative consequences.http://www.european-biotechnology-news.com/news/news/2012-03/bapineuzumab-fails-phase-iii.html


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Bryan Baker">
News 12 at 6 O'Clock, April 7, 2010
AUGUSTA -- They're out there. Dozens of Richmond County sheriff's deputies direct traffic and keep order during a hectic time around Augusta National.
"Usually a dull, boring kind of week," said Lt. Jimmy Young. "A lull before the storm, sometimes, it gives you a chance to get caught up and catch your breath."
Young isn't talking about the Masters Tournament. He means overall crime, which he says decreases annually during Masters Week.
"The makeup of the city just changes Masters Week, and on the west side of the county where all the tournament action is going on, there's just a heavier police presence," he said.
From March 29-31, Monday through Wednesday last week, there were 295 arrests. This week, also Monday through Wednesday, there were 187 arrests--over 100 fewer. That's despite the fact that thousands more people are concentrated in one area.
Burglaries and other thefts have dropped. But so have violent crimes, like assault.
Then there's soliciting business from the roadway. 46-year-old William Assel, Jr. of New York was charged with it on Washington Road. RCSO says he likely was selling or buying tickets. He posted bond and has been released.
And though the calls and the crimes have slowed down for investigators, they expect there won't be much of a break.
Said Young: "Next week it will go right back to normal."


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Ten Bay Area college basketball milestones on the horizon
Here are 10 targets on the horizon for Bay Area players or coaches:
12 -- Victories coach Mike Montgomery needs to reach 100 in his fifth season at Cal.
15 -- Victories Saint Mary's College coach Randy Bennett needs to reach 250.
19 -- Victories Montgomery needs to become the first coach to win 500 games in the Bay Area.
20 -- Victories by senior point guard Matthew Dellavedova to reach 100 in four seasons at Saint Mary's.
25 -- Coaching victories Johnny Dawkins needs to reach 100 at Stanford.
46 -- Points Santa Clara senior Kevin Foster needs to break the school record of 1,691 by Kurt Rambis (1976-80).
70 -- Points junior Allen Crabbe needs to become the 42nd Cal player to score 1,000 for his career.
151 -- 3-point field-goal attempts needed by Santa Clara's Foster to reach 1,000 for his career.
309 -- Points Foster needs to become the fourth Division I player in Bay Area history to score 2,000 for his career, joining Stanford's Todd Lichti and Adam Keefe and USF's Bill Cartwright.
495 -- Points Dellavedova needs to eclipse the Saint Mary's career record of 1,874 set by Daniel Kickert (2002-06).


text:
|Amount Per Serving
|% Daily Value
|Vitamin C
|250 mg
|22 mg
|Niacin (as Niacinamide)
|30 mg
|Folic Acid
|250 mcg
|Vitamin B12
|35 mcg
|Beta Alanine
|1500 mg
|Creatine Nitrate
|1000 mg
|Arginine AKG
|1000 mg
|Explosive Energy Blend
|741 mg
|Vitamin C (as Ascorbic Acid)
|Caffeine Anhydrous (135mg)
|Mucuna Pruriens (standardized for L-Dopa)
|Bitter Orange (Citrus Aurantium) (fruit) (30% Synephrine) (Advantra Z)
|Folate (as Folic Acid)
|Pyridoxal 5-Phosphate
|Vitamin B12 (as Methylcobalamin)
Directed Use on Training Days: To determine tolerance, begin by taking one serving (1 scoop) mixed with (4-6 oz) of water 20-30 minutes before training. After personal tolerance has been assessed, take one to two servings (1-2 scoops) 20-30 minutes before training begins. Add (4-6oz) of water for each serving. During your workout, it is recommended that you drink plenty of water.
Advantra Z is a registered trademark of Nutratech Inc. under U.S. patents 6,224,873; 6,316,499; 6,340,481; 6,340,482
Important Disclosure: This product may contain legal dietary ingredients that are prohibited by Sports and/or cause a false positive for banned or prohibited substances ("PS"). Due to the unique restrictions of amateur and professional sports organizations, the Armed Forces, law enforcement and other agencies and employers, as well as the possibility of legal dietary ingredients causing a false positive for PS, do not take this product if you are subject to PS testing without the approval and/or authorization of the organization, entity, agency or governing body that requires the testing.
|1 Scoop (5.9g) Contains:
|and more
Servings: 60
Serving Price: $0.84
Sweeteners: Sucralose, Acesulfame-k
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The Ashland City Council on Tuesday unanimously approved cost-of-living adjustments and incentive bonuses for Ashland Police Association members that will cost an estimated $96,664.
Members of the police union have gone without COLA increases in two of the three years of their last contract, which expired June 30.
On Tuesday night, councilors approved a variety of increases in a new three-year contract.
Police will receive a 2 percent raise this fiscal year and 3 percent increases each year in the second and third years of the contract.
Police with an associate degree will get 2 percent raises, those with a bachelor's degree will get 3 percent raises and those with a master's degree will get 5 percent raises.
Police will receive 2 percent raises after attaining 10 years of continuous service and 4 percent raises for achieving 15 years of continuous service.
They can earn an extra $500 in the first year of the contract by achieving fitness targets and $600 each year during the following two years of the contract for reaching those goals.
Earlier this year, the City Council approved pay raises and COLA increases that averaged 3.4 percent for city government employees not represented by unions, such as department heads.
The department heads had gone without COLA increases or pay raises since 2008, when the city's finances were hurt by the recession.
Employees in an electrical workers' union are receiving 2.5 percent COLA increases this year, and workers in a laborers' union are receiving a 2 percent increase.
Staff reporter Vickie Aldous can be reached at 541-479-8199 or email@example.com.
Location, ST | website.com


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People weren't getting their jobs through their friends. They were getting them through their acquaintances. Why is this? Granovetter argues that it is because when it comes to finding out about new jobs -- or, for that matter, new information, or new ideas -- "weak ties" are always more important than strong ties. Your friends, after all, occupy the same world that you do. They might work with you, or live near you, and go to the same same churches, schools, or parties. How much, then, would they know that you wouldn't know? Your acquaintances, on the other hand, by definition occupy a very different world than you. They are much more likely to know something that you don't. To capture this apparent paradox, Granovetter coined a marvelous phrase: the strength of weak ties. Acquaintances, in short, represent a source of social power, and the more acquaintances you have the more powerful you are.
Malcolm Gladwell
Source: The Tipping Point: How Little Things Can Make a Big Difference, Pages: 54
Contributed by: ~C4Chaos
Copyright © 2016 Gaiam, Inc.


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It's difficult to really value the Boston Celtics' recent victory over the Sacramento Kings. Calling the Kings a bad basketball team isn't completely fair, they do have some level of talent in spite of their 17-30 record on the season. However, when they came to TD Garden on Wednesday night, they brought with them some of the worst play that has been on show all season. Highlights of the constant futility were multiple missed open layups, an inability to play team defense and a shooting percentage of 39 that was bloated by a second half of garbage time.
Because of the Kings inability to run an effective team on either end of the floor, despite their advantage in the paint on paper, the Celtics' impressive display and victory must be considered lightly. Yes, Leandro Barbosa, Courtney Lee and Jason Terry played well in Rajon Rondo's absence. Brandon Bass even impressed in his 38 minutes on the floor after an early injury to Jared Sullinger forced him onto the floor. Kevin Garnett and Paul Pierce combined for 19 rebounds, nine assists and 29 points. But no, Lee and Avery Bradley weren't tasked with running the offense against any kind of resiliency in a clutch situation. Terry and Barbosa's ability to defend the perimeter was similarly left unchallenged, while the Celtics' bigs were able to execute for similar reasons.
What was promising, was the fact that the Celtics got contributions from their whole roster. Every healthy body played, with eight players finishing the game with at least seven points. Even though the opposition wasn't playoff caliber, the ability to execute and effort that existed post-Rondo was as impressive as ever. Couple that display with the double over-time victory over the Miami Heat, and Celtics fans could be forgiven for thinking that their season may have more life in it than most think.
The Celtics can't be ruled out from making a run in the playoffs. The fragility of the Eastern Conference puts just three surefire contenders in their way. Along with the Miami Heat, who are clearly the favorites despite their somewhat inconsistent regular season, the New York Knicks and Indiana Pacers will both feel confident of competing for that elusive spot in the NBA Finals. Even with a healthy Rondo, the Celtics would have needed to compensate their lack of individual talent compared to those teams, with intelligence from the coaching staff and team execution on the floor to be competitive.
A blueprint was laid out against the Heat on Sunday night. Fortunately for the Celtics, Rondo wasn't a primary part of the Celtics' defensive gameplan to stop the big three. With Avery Bradley fully healthy after his shoulder issues entering the year, the Celtics have a shutdown shooting guard who can contain Dwyane Wade. Paul Pierce may be a limited offensive weapon at this point in his career, but he has always played good defense against Lebron James. James can't be stopped, but making him earn every point he gets is something few players can do. Pierce does that. The final part of the big three, Chris Bosh, presents the problem of length that should hurt the Celtics significantly. However, because Bosh plays so far from the basket and is much more of a finesse finisher than dominant force, Kevin Garnett has never felt outmatched in their duels.
Beating the Heat in a seven-game-series requires you to do many things. The most important thing to do is contain the big three however. The Celtics have the pieces in place to do that, even if they are overmatched elsewhere. If Jared Sullinger can overcome his back issues and continue to develop into the player he is proving to be, the Celtics would actually match up very well with the Heats' starting five as Courtney Lee and Mario Chalmers finish off both lineups. Surpassed the starters, the Heat have much different styles of players. Ray Allen doesn't need any introduction, while Shane Battier, Rashard Lewis, Norris Cole, Joel Anthony and Mike Miller all offer different difficulties to oppose. For the most part, the Heat have veterans to rely on who have proven themselves repeatedly at this level and in the post-season. The Celtics have less experience, but no less potential.
Even though the Celtics' bench doesn't have the same kind of experience as the Heat's, there is plenty of potential to get quality play on the court. Barbosa and Terry are both proven scorers at any level. Brandon Bass is a former starter, while Chris Wilcox and Jason Collins can both compete with the Heats' bigs. The key for the Celtics is Jeff Green. From a sheer physical abilities perspective, Jeff Green has the ability to take over any team's opposing bench players. However, Green is still adjusting after missing last season for heart surgery. How Green continues to develop over the coming months will be crucial if they find themselves facing the Heat again in the playoffs.


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Game Haiku – 06/11/09 – Cardinals 6, Marlins 5
Pujols' smacks homer
off upper deck. Key hits from
Ankiel seal the win.
Pujols' smacks homer
off upper deck. Key hits from
Ankiel seal the win.
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I'll be on this @ 10 then swap over to Gears when I get bored.
I'll be on this @ 10 then swap over to Gears when I get bored.
Decided to do some searching on region filters and Gears and found out Judgement took away DBNO. So now you just die, no more downing. And the Locust aren't in the campaign at all.
Yep. People are going apeshit on the forums over there.
So, just finished Halo 4. 343i did the impossible: they actually made me care about the Chief as a character. So, there's that.
In other news, I'll be playing MP a fair bit more now. If anyone wants to play, my GT is VoltySquirrel.
I've really grown to hate Haven.
Haven is a good map it's just overplayed to fucking death.
Also, me and rob were on today but Usedtabe needs his sleep to prepare for the jesus dick tomorrow.
Did some digging on Gears3/Halo4 connection issues and it all boils down to Microsoft's cheapness. At Gears launch,they hosted the servers but now they contract them out in "clusters" to other companies. So based on where you live you get put in a "region" which could consist of any number of areas.
Talked with support on Twitter today and dude first tried to act like matchmaking was fine till I pointed him to the 62 page thread on the halowaypoint forums and the twitter tag #Halo4Everyone. Then he tried to suggest amatuer connection troubleshooting like it was my end. So I asked him "if you know of a solution I can do on my end to make it so I only connect to players in the US I'm all ears".
He replied there was no way he knew to do that, therefore acknowleding what everyone who's had to deal with this shit has known, it's MS fucking up,not our connections. I pushed further by stating that this is only a problem on Halo 4 and Gears 3, which coincidentally are governed completely by Microsoft's matchmaking system. His final solution was for me to suggest better regional filtering at a suggestion link.
So this will continue to be an issue for future Microsoft Studios games. Even GOW:J will have the same flaws as Gears 3 because MS will again be "hosting" the servers. My guess is they favor finding a match quicker than they favor finding a better connection for everyone. Bungie had the option in Reach to search by connection and it worked. Microsoft is still rolling with the shitty Halo 2 matchmaking.
I feel really good about the yearly subscription I pay to get sub-PSN quality online gameplay. How would I ever know of the Big Mac without those McDonalds ads choking up my dashboard on loadup?
I'm seriously considering that or just switching to PC gaming. I pay $60 a year to get lumped in with Canada/Mexico because that's what they have my region determined as. Fuck that.
Yeah, PC is the way I see myself drifting towards next gen. The games are cheaper and there's none of this "give-me-money-and-I'll-give-you-advertisements-in-exchange" bullshit.
Sony's doing it right with PS+. You're actually getting content that is worth paying for that you can't get elsewhere for free. Same cost, vastly superior bonuses to the consumer.
We'll see how it ends up but I see myself drifting from MS more and more unless they adopt a set-up similar to PS+. At the VERY effing least remove ads from Gold subscribers. Their little scratch-off thing is a cheap way out of the "well we give free shit too" deal considering maybe 75 people a week manage that.
I blocked their stupid ad server on my router ages ago but the spinning wheel deals are annoying.
Gonna be on this tomorrow night.
They removed King of the Hill. The fuck?
I want to love this game but so many things are fucked about it right now.
I think it's time that me and Master Chief take a trip to Gamestop today, because that is just beyond fucking dumb. I've got too many other shooters competing for my time to dawdle with 343's bullshit.
Maybe I'll use the money to get BLOPS 2 and try out for El Presador's clan. Then I can finally realize my dream of MLG stardom.
I wouldn't trade it in yet. They're (most likely) just doing what should have been done from the beginning, putting all objective gametypes together.
They also cycled Slayer Pro out.
Somewhat infuriating on Legendary this game.


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RICHMOND -- Bruce Beyaert says it takes a village to build a trail -- especially along the long and winding shoreline of this old industrial town.
Friends and supporters, however, credit the tenacious trail advocate and his volunteer group for bringing together a large cast to create the biggest segment so far of a planned 500-mile trail around the entire San Francisco Bay shoreline.
Thirty-two of the 42 planned Bay Trail miles in Richmond are now complete, knitting together a necklace of parks among new waterfront homes and offices and old gray industries, docks and boatyards.
None of the 46 other cities along the Bay Trail has so much trail finished, nor do they have as much shoreline. The whole trail, on which work began in 1987, is about 60 percent done.
It wouldn't have happened so fast if not for Beyaert and his spirited group called TRAC, or Trails for Richmond Action Committee
"Bruce's leadership has been essential to the trail. He is smart, pleasant but tenacious," said Richmond City Councilman Tom Butt, "and TRAC has focused attention on the Richmond shoreline trail like a laser. They just never give up."
The trail is part of a Richmond shoreline renaissance that attracts hikers, joggers, and riders from inside and outside the city to the path.
On a recent sunny weekend morning, several people were riding and hiking the trail, savoring views of the vast Bay, the islands and boats in it, and bridges across it.
"Hiking, jogging and or riding along San Francisco Bay, how can you have it any better?" Beyaert asked as he walked from Point Potrero, a former shipbuilding center, to Ferry Point, a former dock and railroad terminus for ferries crossing the Bay.
"For mental and physical health," he said, "it's really important for people to get in open space and get away from the pressures of urban life."
Beyaert, 77, an avid Richmond hiker and former top environmental manager for Chevron USA worldwide, plays down his own efforts.
He's proud to boast, however, about his group's work.
TRAC has worked with landowners, neighbors, walkers, bike riders, business owners, developers, industry and railroad managers, environmental planners and scientists, politicians and many city, regional, state and regional agencies.
Within Richmond, the city and East Bay Regional Park District oversee the trail construction, but TRAC assists in many ways behind the scenes.
"Planning trails is a group effort," Beyaert said. "It often is not easy. It can take years to get one little section."
To assemble one deal for a trail section near Brickyard Cove, the group talked Santa Fe railroad into selling land to one private land owner so a trail could be financed by yet another shoreline landowner.
When a potential snag emerged, TRAC lined up yet another company to remove and recycle the railroad rails that were in the way.
"We even made a little money for the rail recycling," Beyaert said. "We plowed it right back into our trail work."
TRAC has little money, but it has helped Richmond land more than $7 million in shoreline trail grants by writing grant applications. Another volunteer has written text for history panels on the path.
The diverse group of volunteers in TRAC include an environmental shoreline planner, a retired news editor, a historian, a web designer, boaters and bicyclists.
The trail has grown from a tiny start.
Richmond had just 65 feet of shoreline accessible to the public in the mid-1960s when a public outcry over filling up the Bay for development produced a state law to protect the waterway and provide public access.
Richmond had 12 miles of shoreline trail -- most in a series of parks -- in 1999 when Beyaert decided to found TRAC with the encouragement of several conservation leaders.
"We realized we need to build a constituency for the trail," Beyaert said.
So the group recruited an e-mail list of more than 2,000 people and groups to write, speak out and lobby for projects.
Beyaert's enthusiasm is infectious.
"He motivates by his example and hard work," said Whitney Dotson, an East Bay Regional Park Board member who serves on the TRAC board.
Last month, Beyaert amped up interest in the trail by hosting a group of eight Bay Area travel writers on a tour of the path and attractions on it -- including the Rosie the Riveter National Historical Park
Beyaert said his group's work won't be finished until the last mile of the Bay Trail through Richmond is finished in a few years.
"We have a way to go," he said. "Our group is looking forward to the day when the trail is complete, our mission is accomplished, and we will have put ourselves out of business."
Contact Denis Cuff at 925-943-8267 or email@example.com. Follow him at Twitter.com/deniscuff
Hometown Heroes, a partnership between Bay Area News Group-East Bay and Comcast, celebrates people in the Bay Area who make a difference in their communities. Read about a new Hometown Hero every other week and watch the video on Comcast On Demand at Channel One-Get Local-Hometown Heroes or at ContraCostaTimes.com/hometownheroes. Do you know a Hometown Hero? Let us know about the work they do at email@example.com.


text:
More Information
Nik Wallenda won't train for Grand Canyon walk in Sarasota
Published: Friday, April 12, 2013 at 3:26 p.m.
Last Modified: Friday, April 12, 2013 at 3:26 p.m.
SARASOTA - Nik Wallenda's hopes of hometown rehearsals for his historic June 23 Grand Canyon wirewalk have hit the wall. So it appears as if the popular Sarasota aerialist will be taking his practice sessions on the road.
"Well, it's disappointing — I was so focused on thinking Benderson Park was going to happen, I didn't really have another location picked out," said the 34-year-old high-wire record holder. "I should've paid more attention to that."
Wallenda had been negotiating with Nathan Benderson Park officials to host practice sessions at the end of May or early June. But with construction underway to prepare for the USRowing Masters Championships in August, project overseers said they needed to stay focused on park development.
"It was a little too challenging because of the ongoing construction. Logistically, it's not a safe environment," Mark Chait, Benderson's executive director of planning, said on Friday. "The timing just wasn't right."
Rehearsing for the estimated 1,400-foot-long Grand Canyon cable walk requires enough space to accommodate two cranes, an operation Wallenda says costs $150,000 to rig. His team needed investors to absorb the costs.
"It's really too bad, because Nik has been so good to us and generous to the community," said Virginia Haley, president of Visit Sarasota County. "We could pledge a certain chunk of change, but we needed help from somebody who would value that kind of exposure."
The bulk of that exposure was not anticipated through local fan turnout and regional coverage, but from Discovery Channel — which will televise the Grand Canyon skywalk live — and its potential cable audience of roughly 1 billion viewers.
"We were looking at a later impact," Haley said, "because a lot of the programming will focus on his training."
Wallenda said he wanted to perform at Benderson because "It's a beautiful place, a perfect location with all the water, and a great showcase for Sarasota."
Wallenda, whose Niagara Falls wirewalk drew a time-slot bonanza 13.1 million viewers last year for ABC, is exploring other training options, including the King's Island amusement park outside Cincinnati.
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.


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SMBs stay ahead of the game
The game is always changing for small and midsize businesses. You need to be lean and stay lean, so you never invest a cent more than needed, but scale instantly when required. You need to do business anywhere and be faster and bolder than the competition. And you need to leverage all of your data to its fullest to target the right opportunities and win sales. In each of these areas, Microsoft offers tools and technologies that can help you stay ahead of the game. And when you're ahead of the game, you lead.Download the Windows Server 2012 R2 Essentials trialDownload the Windows Server 2012 R2 trialConnect with your IT provider, or find one at Pinpoint
Be lean and stay lean
In today's business environment, doing more with less has become the new normal. Now it is imperative to get the most out of every investment. Technologies such as virtualization and the cloud can enable you to achieve your business goals more cost-effectively by helping you get more value from IT while reducing or eliminating up-front costs. Microsoft is a leader in the 2013 Gartner Magic Quadrant for Server Virtualization for the third year in a row. Why pay more to virtualize with VMware when you can get a leading virtualization platform built in at no extra cost with Windows Server 2012?
Do business anywhere
As the division between personal and business lives blur, more people are working from home, from the office, and on the road—and using a growing assortment of mobile devices to do this work. This flexibility can create great business benefits by fostering happier, more productive employees.
But it can also create IT management headaches and data security risks. Now, with Windows Server 2012 you can provide your employees with the freedom to do business nearly anywhere they need to be—and have peace of mind from a platform that helps protect your data. Do your employees have the flexibility to do business anywhere?
Tap your data goldmine
Most organizations are sitting on a goldmine of information, from customer purchase histories to product profitability data. Those who can use data to their advantage will win. The challenge is to get visibility into your data—to gain the insights needed to target the most profitable customers and win new sales. Now it is possible to use familiar tools such as Microsoft Excel to get to the data you need, and to use that data to generate the insights that will help you grow your business. Are you using your data to help you stay ahead of the competition?


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Working with The Manchester College, Band on the Wall offers accredited courses for developing the skills needed to work in the music industry.
Band on the Wall's Creative Music Programme, run by our Education partner Brighter Sound includes a range of opportunities for inspiring, non-formal, hands-on learning.


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Budget Could Focus on Teachers & Health Care
Published: Sunday, March 3, 2013 at 12:27 p.m.
Last Modified: Sunday, March 3, 2013 at 12:27 p.m.
TALLAHASSEE | For the first time in six years state lawmakers aren't grappling with billion dollar shortfalls in the state budget.
Florida legislators are expected to pass a new state budget during the 60-day session that does not call for large spending cuts.
Instead the tug-of-war during the session will likely be over how to spend a modest budget surplus. Another big budget question is whether the state will accept federal aid and expand the Medicaid program to cover more Floridians.
Gov. Rick Scott has proposed a $74.2 billion budget that includes an across-the-board pay raise for teachers as well as bonuses for state workers. Scott also supports the Medicaid expansion which is part of the federal health care overhaul.
Legislative leaders have been reluctant to endorse the teacher pay raise proposal.
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.


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Video Rating: 0 / 5
www.jeffjellis.com – Learn how to automate Facebook updates whenever you post to your blog using the "Wordbook" WordPress Plugin as well as the RSS Graffiti Facebook Application.
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Product prices and availability are accurate as of the date/time indicated and are subject to change. Any price and availability information displayed on Shop MLB.com at the time of purchase will apply to the purchase of this product.
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Raloxifene and Rimostil for Perimenopause-Related Depression
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of this study is to evaluate the effectiveness of the drugs raloxifene and rimostil in treating perimenopause-related depression.
Perimenopause-related mood disorders cause significant distress to a large number of women; the demand for effective therapies to treat these mood disorders is considerable. Estradiol replacement therapy (ERT) has demonstrated efficacy in treating perimenopause-related depression. Unfortunately, there are long-term risks associated with ERT. Selective estrogen receptor modulators (SERMS), such as raloxifene, and phytoestrogens, such as rimostil, have estrogen-like properties and may offer a safer alternative to ERT. The effect of SERMS and phytoestrogens on mood and cognitive functioning need to be examined in women with perimenopause-related depression.
Participants in this study will undergo a medical history, physical examination, electrocardiogram (EKG), and blood and urine tests. They will then be randomly assigned to receive one of four treatments for 8 weeks: raloxifene pills plus a placebo (an inactive substance) skin patch, rimostil pills plus placebo skin patch, estradiol skin patch plus placebo pills, or placebo patch plus placebo pills. Participants will have clinic visits every 2 weeks. During the visits, blood will be drawn and participants will meet with staff members and complete symptom self-rating scales. A urine and blood sample will be collected at the beginning and end of the study. At the end of the study, participants who received placebo or whose study medication was ineffective will be offered treatment with standard antidepressant medications for 8 weeks. Non-menstruating women will receive progesterone for 10 days to induce menstrual bleeding and shedding of the inner layer of the uterus, which may have been stimulated by the study medications.
Perimenopausal Depression
Drug: Raloxefine (Evista)
Drug: Rimostil
Drug: Evista, Rimostil, Alora
Phase 4
|Study Type:
|Study Design:
|Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:
|The Efficacy of Phytoestrogens and Selective Estrogen Receptor Modulators in Perimenopause-Related Depression
- Mood Rating Scales [ Time Frame: Every 2 weeks ] [ Designated as safety issue: No ]
- Cognitive Test Measures [ Time Frame: Basaeline and Week 6 ] [ Designated as safety issue: No ]
|Study Start Date:
|February 2002
|Study Completion Date:
|June 2015
|Primary Completion Date:
|June 2015 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: 1
Dose of 60 mg per day for eight weeks
|Drug: Raloxefine (Evista)
Experimental: 2
Dose of 1000 mg twice a day for eight weeks
|Drug: Rimostil
Active Comparator: 3
Dose of 100 micrograms a day by skin patch for eight weeks.
|Drug: Evista, Rimostil, Alora
Detailed Description:
Perimenopause-related mood disorders cause significant distress to a potentially large number of women. The demand for effective therapeutic alternatives to estrogen for treating these mood disorders is considerable, as is the need to define clinical or biologic markers that may predict successful response of mood disturbances to phytoestrogens or selective estrogen receptor modulators (SERMs). Further, the study of potential biological mechanisms underlying both perimenopause-related mood disorders and their response to treatment may offer the possibility of uncovering some etiopathogenic mechanisms involved in these and related mood disorders.
Results of protocol # 90-M-0077 demonstrated the therapeutic efficacy of estradiol therapy (ET) in perimenopausal depression, independent of its effects on vasomotor symptoms. Nevertheless, the long term risks of ET to endometrial and breast tissues continue to deter many women from its use. Recently, selective estrogen receptor modulators (SERMs) and phytoestrogens (plant-derived estrogen-like compounds) have become available and are reported to display both tissue-specific profiles of estrogen agonist and antagonist actions and differential affinities for the two forms of estrogen receptor. For many women, these novel compounds would represent a safer alternative to ET for the prevention of osteoporosis and the treatment of menopausal symptoms. However, the effects of SERMs and phytoestrogens on mood and cognitive function in perimenopausal women remain undetermined.
In this protocol we wish both to investigate the effects of SERMs and phytoestrogens on mood and cognition under placebo controlled conditions and to compare these effects with estradiol therapy. This protocol will address the following questions: 1) Do selective estrogen receptor modulators or phytoestrogens improve mood and cognition in perimenopausal depressed women? 2) Are the mood and cognitive effects of SERMs and phytoestrogens comparable to those of ET? and 3) Do selective estrogen receptor modulators and phytoestrogens improve measures of bone metabolism in perimenopausal depressed women?
|Ages Eligible for Study:
|40 Years to 60 Years (Adult)
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Subjects for this study will meet the following criteria:
- Self-report of the onset of depression associated with menstrual cycle irregularity or amenorrhea;
- A current episode of minor (meeting 3-4 criterion symptoms) or major depression (of moderate severity or less on the Structured Clinical Interview for DSM-IV (SCID) severity scale and not meeting DSM-IV criteria symptom 9 (suicide)) as determined by the administration of the minor depression module of the Schedule for Affective Disorders and Schizophrenia - Lifetime Version (SADS-L). Additionally, to ensure that subjects meet a minimum threshold for severity of depression, subjects will have scores greater than or equal to 10 on either the Beck Depression Inventory (BDI) or the Center for Epidemiologic Studies - Depression (CES-D) Scale during at least three of the four clinic visits during the two month screening phase, as well as a 17 item Hamilton Depression score greater than or equal to 10. Subjects will be excluded if they meet any of the following criteria: major depression of greater than moderate severity, DSM-IV criteria # 9 (suicide), or anyone requiring immediate treatment after clinical assessment or functional impairment ratings of five or six for more than seven consecutive days on daily ratings;
- Evidence of perimenopausal reproductive status;
- Age 40 to 60;
- No prior hormonal therapy for the treatment of perimenopause-related mood or physical symptoms within the last six months;
- No history of psychiatric illness during the two years prior to the reported onset of the current episode of depression;
- In good medical health, and not taking any medication or dietary and herbal supplements on a regular basis (with the exception of multivitamins and calcium supplements).
The following conditions will constitute contraindications to treatment and will preclude a subject s participation in this protocol:
1) Severe major depression with any of the following:
- positive (threshold) response to SCID major depression section item # 9, suicidal ideation;
- anyone requiring immediate treatment after clinical assessment;
- severity ratings greater than moderate on the SCID IV interview;
- functional impairment ratings of five or six for more than seven consecutive days on daily ratings.
2) Current treatment with antidepressant medications. Our main concern is to exclude subjects taking medications that would treat or precipitate depression or adversely interact with reproductive hormones, phytoestrogens (e.g., anticoagulants), or SERMs. Thus, we wish to exclude only women receiving psychotropic medications, medications that have been reported to induce a change in mood or behavior, hormone replacement therapy, oral contraceptive agents, or medications that may have a potential adverse interaction with the compounds employed in this study.
3) History of psychiatric illness during the two years before the reported onset of the current episode of depression.
4) History of ischemic cardiac disease, pulmonary embolism, retinal thrombosis, or thrombophlebitis; any subject with risk factors for thrombo-embolic phenomena including cigarette smokers; varicose veins, patients with prolonged periods of immobilization (including prolonged travel), and active heart disease. The literature suggests that although both smoking and hormone replacement/oral contraceptives have associated risks of thromboembolic phenomena and cardiovascular events, these individual risks do not become significantly greater when combined until greater than 10 cigarettes a day are consumed. Thus we wish to exclude only subjects for this study who smoke greater than 10 cigarettes per day.
5) Renal disease, asthma.
6) Hepatic dysfunction.
7) Women with a history of carcinoma of the breast, or any women with a family history of the following: premenopausal breast cancer or bilateral breast cancer in a first degree relative; multiple family members (greater than three relatives) with postmenopausal breast cancer.
8) Women with a history of uterine cancer, endometriosis, ill-defined pelvic lesions, particularly undiagnosed ovarian enlargement, undiagnosed vaginal bleeding.
9) Patients with a known hypersensitivity to raloxifene, phytoestrogens (including Rimostil, isoflavones, genistein, daidzein, red clover extract and soy-related compounds), estradiol, Alora, medroxyprogesterone acetate, or the excipients (inactive compounds) contained within these medications including: Rimostil -tocopherols, cellulose, calcium hydrogen phosphate, magnesium stearate, silica-colloidal anhydrous; Provera - calcium stearate, corn starch, lactose, mineral oil, sorbic acid, sucrose, talc; Alora - sorbitan monooleate, acrylic adhesive; Evista - anhydrous lactose, carnauba wax, crospovidone, FD& C blue # 2 aluminum lake, hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate, modified pharmaceutical glaze, polyethylene glycol, polysorbate 80, povidone, and titanium dioxide.
10) Pregnant women.
11) Porphyria.
12) Diabetes mellitus.
13) Cholecystitis or pancreatitis.
14) History of cerebrovascular disease (stroke), epilepsy, hypertension, hypercalcemia.
15) Recurrent migraine headaches.
16) Malignant melanoma.
17) History of familial hyperlipoproteinemia.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00030147
|United States, Maryland
|National Institutes of Health Clinical Center, 9000 Rockville Pike
|Bethesda, Maryland, United States, 20892
|Principal Investigator:
|Peter J Schmidt, M.D.
|National Institute of Mental Health (NIMH)
Additional Information:
|Responsible Party:
|National Institute of Mental Health (NIMH)
|ClinicalTrials.gov Identifier:
|NCT00030147 History of Changes
|Other Study ID Numbers:
|Study First Received:
|February 6, 2002
|Last Updated:
|June 24, 2015
|Health Authority:
|United States: Federal Government
Keywords provided by National Institutes of Health Clinical Center (CC):
Gonadal Steroids
Estrogen Receptor
Mood Disorders
Estrogen Response Element
Perimenopausal Depression
Additional relevant MeSH terms:
Depressive Disorder
Behavioral Symptoms
Mood Disorders
Mental Disorders
Estrogen Receptor Modulators
Raloxifene Hydrochloride
Selective Estrogen Receptor Modulators
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs
Hormone Antagonists
Estrogen Antagonists
Bone Density Conservation Agents
ClinicalTrials.gov processed this record on August 29, 2016


text:
JPS 12U will hold tryouts for the summer season 2012. Tryout dates are January 15th from 2:00 - 5:30 and January 22nd from 2:00 to 5:30. We are commited and accepted to Sparkler Jr. and plan to qualify to attend HOF repectively. Practice field located in northwest Houston, the address is 4613 Creekmont Drive. 77091. Will consider all positions and have 10 committed players. We have an immediate opening for a bracket catcher. Contact Cindy Cowart @ 713-864-1550 or firstname.lastname@example.com. for more information. Regular practice days are Tuesday from 5:30 - 7:30 and Sunday 2:00 - 5:30.
Message was edited by: cindy cowart
if you work harder than the rest - you become the best!
looking for aggressive hard workers with a team first mentality.
Go Juice!
Juice Power Softball
Great work ethic ALWAYS outlasts ability alone!
If you train hard, you'll not only be hard, you'll be hard to beat. - Herschel Walker
Every single day I wake up and commit myself to becoming a better player. Some days it happens, and some days it doesn't. Sure, there are games I'm going to dominate and there are going to be games when I struggle. But it doesn't mean I give up.
You have to expect things of yourself before you can do them.
-Michael Jordan
It's a little like wrestling a gorilla. You don't quit when you're tired you quit when the gorilla is tired.
-Robert Strauss
ACTIVE is the leader in online event registrations from 5k running races and marathons to softball leagues and local events. ACTIVE also makes it easy to learn and prepare for all the things you love to do with expert resources, training plans and fitness calculators.


text:
1.2-3 Constitutional Principles
Revised to September 23, 2013
Every defendant in a criminal case is presumed to be innocent and this presumption of innocence remains with the defendant throughout the trial unless and until (he/she) is proved guilty beyond a reasonable doubt.
The burden is on the state to prove the defendant guilty beyond a reasonable
doubt, and that burden of proof never shifts throughout the trial. Unless you
find at the conclusion of all the evidence that the state has proved beyond a
reasonable doubt that the defendant has committed every element of an offense,
you must find (him/her) not guilty of that offense. On the other hand, if you
are satisfied that the evidence establishes the guilt of the defendant beyond a
reasonable doubt, you should not hesitate to find (him/her) guilty.
[<Include only after discussion with and agreement by defense counsel.> The defendant may or may not testify in this case. An accused person has the option to testify or not to testify at the trial. (He/she) is under no obligation to testify. (He/she) has a constitutional right not to testify. You must draw no unfavorable inferences from the defendant's choice not to testify.]


text:
Application and Admission Process
Thank you for your interest in graduate study at Ohio University. Please read our Admission Requirements and the following before proceeding:
Important Information
Application Deadlines
Application deadlines are set by each academic program. Please review the program website for details. If no deadline is posted, applications should be submitted at least six weeks prior to the intended start term. For international students who need to apply for a Visa, submit your application at least eight months prior to your intended start term.
Application Fees
Application fee(s) are NON-REFUNDABLE including applications submitted in error
|Initial/first Graduate Degree (includes MBA/MSA dual degree)
|US Citizens/Permanent Residents
|Non-Degree/Certificate, Transient
|Second/Subsequent, Reapplication
|Reapplication to Complete a Degree
Application information for McNair Scholars
TO APPLY, select the status that applies to you:
Mailing Address
Any mailed documents should be sent to:
Graduate College
1 Ohio University
220 Research & Technology Center
Athens, OH 45701 USA
If you wish to monitor the arrival of mailed documents, we recommend you utilize the tracking services of the company through which documents were sent.
Applications for degree-seeking status may currently be submitted for:
· Summer semester 2016 and Fall semester 2016 (Sept. 15, 2015)
Applications for non-degree seeking status may currently be submitted for:
· Summer semester 2016
· Fall semester 2016 (week of Sept. 21)
Not all programs admit every term. Available terms are listed for individual programs within the on-line application form.


text:
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There are a range of different types of roof cargo carriers and we have all of them so that you can easily carry exactly what you need on your different journeys. We have a wide range of different carriers like specialized ones that allow you to carry bikes or other equipment or the box-type carriers that allow you to add a trunk to your roof so that you never run out of room again. We have the right brands to give you the quality you deserve and we have it all at lower costs that you would imagine!
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What's up Islander fans?!
This weekend your Islanders traveled to Sam Houston State to take on the Bearkats in the second round of conference play.
Friday morning, at 10 a.m we had practice. The bus ride was going to be so long that the coaches decided it would be a better idea for us to practice before we left, and then relax once we got there, and I would have to agree! We left the school at 12 p.m. and had lunch. I ate chicken nuggets. Mmmm Mmmm good! While we were on the bus we watched a movie. I think we watched two movies but I really don't know, I fell asleep before we hit the highway again lol (ya girl has to get her sleep). When I woke up we had stopped at Buc-ee's! I think it's a Texas thing because I've never seen a Buc-ee's anywhere else in the world lol. Once we left there, we watched, "The Temptations." Everyone on the bus thought they were singers when that movie came on lol. Myeisha (aka Mye) and Zoey (aka Zo) stood up on the back of the bus and started wavin their hands in the air like they were at a concert or something (they're silly).
We arrived to the hotel at about 6 p.m. that evening. Once we got there we checked into the rooms and left for dinner at 7 p.m. We went to a Chinese buffet place, it was really good, but I didn't eat much except for General Tso Chicken and Egg Drop Soup (I <3 Egg Drop Soup). Before we left everyone got a fortune cookie, well my table got two cause we asked for more :). My first fortune cookie was little strange, it said, "A modest man doesn't talk to himself." I didn't like that one much, but my second one said, "As long as you do not start anything new, you'll be fine." I analyzed that just a little bit, and came up with the conclusion that it had two meaning:
(1) I'm doing too much right now and I need to stop starting things until I finish doing other things (this was my first thought)
(2) As long as I don't try to do more than I'm capable of doing then I will do fine in the long run. Forcing things cause for problems later which hinders you more than helps you (this was the second thought, I think this pertained to me more on game days)
Sooooooo, I ended up going with my second thought and allowing myself to do what I could and not forcing myself to do what I can't, depending on the situation that presents itself. Being in my faith, "For I can do all things through Christ Jesus who STRENGTHENS me," allows me to press forward through any situation and persevere.
The game started at 2 p.m. which is earlier than normal for us, but we had shoot around at 7:30 a.m. After shoot around we went and ate breakfast. All I ate was biscuits and gravy because I don't eat eggs (they are disgusting to me). Then back to the hotel for a pre-game nap.
Tip-off!!! We were soo energized at the beginning of the game and went up by 14 at the half. But idk what happened after halftime, but it went downhill from there and we never got it back. We ended up losing 75-54. This made it a long quiet bus ride home.
On the way home, we found out that the Queen of Pop and icon Whitney Houston had passed away in her hotel room in Beverly Hills, the afternoon before the Clive Davis pre-Grammy party and the day before the Grammy's! It was a tragic loss in the music industry and to the world. My prayers go out to her 18 year-old daughter Bobbi Kristina and the rest of her family!
On another note, I hope you have a safe and fun Valentine's Day with your loved ones. Shoutout to my other bestie Xinia Zepeda for the Chocolate Covered Strawberries (my favorite), and my best friend Da Da who is going to be my valentine this year lol! Best friends make the best valentines!! Lol
I hope to see you all tomorrow for our Play 4Kay Breast Cancer Awareness game against Texas State, in honor of our athletic academic advisor Jennifer Baker. Wear pink to show your support!! $3 of every single game ticket will benefit breast cancer awareness and patient care. The first 500 fans will receive a Pink drawstring backpack courtesy of CHRISTUS SPOHN. Tip-off is at 7 p.m.!! Can't wait to see you!!!
*Fun Fact* I made a wolf dog today in the University Center for Valentine's Day!! (pic below) Her name is: *drumroll*……………. Twinkle (she has blue eyes)
Well until next time Islander Fans!!
^-_-^ Twinkle


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TEDA appoints 2013 executive committee
Published: Tuesday, November 13, 2012 at 6:38 p.m.
Last Modified: Tuesday, November 13, 2012 at 6:38 p.m.
Terrebonne Economic Development Authority appointed its executive committee for 2013 at its meeting Tuesday.
Vice Chairman Clarence Williams of Technical Marine Maintenance Services Louisiana, LLC will replace Don Hingle of Business First Bank as chairman. TEDA member Katie Sims of Pink Flamingo Properties, LLC will replace Williams as vice chairwoman. Christian Lapeyre of Alford, Staples, Lapeyre & Robichaux Insurance will remain secretary and Stephen Smith of All South Consulting Engineers will remain treasurer.
The member at large is the last position to be filled on the committee and is usually chosen sometime in January by the chairman.
"I'll be looking for someone who is compassionate about what TEDA is about and what TEDA is trying to do, someone who is willing to work with others, someone who has a can-do attitude, someone who respects the fact that we work in a group as a team and not as an individual," Williams said.
TEDA board members are from different businesses and organizations around the area.
"Members are nominated by their organization, and the organization submits their name to the Parish Council. The Parish Council votes on the person they wish to be on our board," said Megan Benoit, TEDA director of communications.
Staff Writer Sable LeFrere can be reached at 985-857-2204 or at email@example.com.
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.


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NC House backs Asheville CTS, Camp Lejeune plaintiffs
Published: Friday, June 13, 2014 at 11:24 a.m.
Last Modified: Friday, June 13, 2014 at 11:24 a.m.
RALEIGH, N.C. — Legislation has moved quickly through the North Carolina House seeking to clarify a judicial rule cited by the U.S. Supreme Court this week in blocking people in Asheville from suing for damages over contaminated water.
The chamber voted unanimously Friday to change what's called the "statute of repose," which bars lawsuits brought more than 10 years after any alleged contamination occurred. The proposal tries to make clear that the 10-year period should not be interpreted as barring personal-injury cases involving certain groundwater contamination.
House members are hopeful the clarification will make it possible for litigation by Asheville homeowners near an electroplating business to move forward, as well as a lawsuit blaming contaminated tap water at Camp Lejeune for illnesses.
The measure goes to the Senate early next week.
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The Louisville Cardinals and the Michigan Wolverines will square off in this year's NCAA men's tournament national championship game to be played Monday in Atlanta.
Title game set: It's Louisville and Michigan
Published On: Apr 09 2013 06:54:48 PM EDT Updated On: Apr 07 2013 12:16:36 AM EDT
The views expressed are not those of this site, this station or its affiliated companies. By posting your comments you agree to accept our terms of use.blog comments powered by Disqus


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It's no secret: the Augusta National is looking for room to grow.
And that means real estate around the famous fairways is a hot commodity these days.
Augusta National is buying up property and losing some of its neighbors as a result.
News 12's Kate Tillotson spoke with an area homeowner.
Heath Drive, on the opposite side of Berckmans Road from the Augusta National, is filled with folks who built their homes in the 40's. Those homes will likely be torn down...but the payoff could be huge.
"People in this neighborhood didn't move in and out, they just came and stayed," says Dorothy Jones, who's lived on Heath Drive for 57 years. "And we've watched the trees grow."
Some of them she planted herself.
But even so, Jones was ready to sell.
"I'm sure the day that they bulldoze the house is going to break my heart, but it's coming. There's nothing we can do about it," she says.
Jones is one of several homeowners who'll be moving this year after selling their property to Augusta National. Her lot is located just west of the course.
The National pushes right up against Berckmans Road, making Heath Drive prime real estate if it were to expand.
"We continue to acquire property outside our boundaries," said Augusta National chairman Hootie Johnson in an interview last week. In the interview, he outlined his plan to help make room for a new practice area slated for 2010.
"Help us accommodate the 3000 cars that we'll have to move from that area for the facility. That's about it," he said.
"They were going to get it eventually," Jones says.
While Jones reflects on decades of memories, she can't deny the domino effect of one house sale after another after another.
And still she's not sure what will come of the home she's built from scratch.
"They won't tell you what they're going to do with it. They know but we don't," she says.
Jones has a great attitude, but she's sworn to secrecy about talking money. She wouldn't say what she got for her home, but she says it was fair.
News 12 spoke with another homeowner who also recently sold to the National. He tells us he got almost everything he asked for, including four lifetime Masters badges and two years of rent-free living.
Sounds like a pretty sweet deal.


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In a bizarre turn for a political convention, Clint Eastwood carried out an imaginary conversation with Barack Obama, represented by an empty stool onstage.
The Dirty Harry actor's performance ranged from biting to rambling, with lots of jokes and a salty touch.
"I've got Mr. Obama sitting here and I was going to ask him a couple of questions," Eastwood told the delegates, gesturing to the stool, before pretending to question Obama about the wars in Iraq and Afghanistan and whether he should have tried to close the Guantanamo Bay prison for terror suspects.
At one point he "listened" to the imaginary Obama lash out at Romney -- leaving the president's side of the conversation to the audience's imagination.
"He can't do that to himself. You're absolutely crazy!" Eastwood reacted. "You're getting as bad as Biden."
Stern-faced Romney aides winced at times as Eastwood's remarks stretched on. On a night where virtually every moment was scripted, Eastwood was among the only speakers not reading from a teleprompter as he spoke. It was blank.


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Chesnee woman charged with driving under the influence and child endangerment
Published: Saturday, February 2, 2013 at 9:41 p.m.
Last Modified: Saturday, February 2, 2013 at 9:41 p.m.
A Chesnee woman is charged with driving under the influence and child endangerment after deputies found her passed out behind the wheel Friday afternoon at a stop sign on South Blackstock Road.
Spartanburg County Sheriff's deputies say a witness called police when she saw Emmie Lou Crocker, of 250 Simmons Drive drive off the road several times. When authorities arrived on scene they found Crocker, 32, slumped over behind the wheel at the stop sign of South Blackstock Road and Highway 11 with a child in the back seat.
According to a deputy's report, Crocker initially told deputies her condition was a result of low blood sugar from diabetes. She voluntarily allowed officers to search her car and one deputy was stabbed with a needle while checking Crocker's purse. Officers also found two spoons in her purse.
The child was put in the custody of another adult and Crocker was taken to Spartanburg County Jail.
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"In order to free the fiction of the sovereign State--in other words, the whims of the chieftains who manipulate it--from every wholesome restriction, all socio-political movements tending in this direction invariably try to cut the ground from under religion. For, in order to turn and individual into a function of the State, his dependence on anything else must be taken from him. Religion means dependence on and submission to the irrational facts of experience. These do not refer directly to social and physical conditions; they concern far more the individual's psychic attitude. But it is possible to have an attitude to the external conditions of life only when there is a point of reference outside them. Religion gives, or claims to give, such a standpoint, thereby enabling the individual to exercise his judgement and his power of decision. It builds up reserve, as it were, against the obvious and inevitable force of circumstances to which everyone is exposed who lives only in the outer world and has no other ground under his feet except the pavement. If statistical reality is the only one, then that is the sole authority. There is then only one condition, and since no contrary condition exists, judgement and decision are not only superfluous but impossible. Then the individual is bound to be a function of statistics and hence a function of the State or whatever the abstract principle of order may be called."
Carl Gustav Jung
Source: Civilization in Transition ((The Collected Works of Carl G. Jung Volume 10)), Pages: Paragraphs 505-506
Contributed by: manofflowerz
Copyright © 2016 Gaiam, Inc.


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HAWLEY - Lake Region Fitness in the Hawley Silk Mill and Designer Body Works in Honesdale have united to host "ID Life," a nutrition program where two towns have one goal to help people get healthy and stay healthy for life.
A 90 day challenge by ID Life, starting June 21 folks can work to improve their health and wellness, while participating in a supplement challenge at either gym. One membership can be used at both gyms at no additional cost.
To take a class at either gym, the cost is $3.00 for members. The June 21 challenge will kick off the summer. As part of the challenge, there will be weigh-ins/measurements during the week of the 16th - 20th at the participants' convenience at either gym. Both men and women will be available for the measurements to ensure participants are comfortable.
The first place winner will receive a vacation of their choice to a destination with $200 towards airfare. Second place will receive a free one year membership to either gym. The third place winner will receive $150 in products. Visit www.LakeRegionFitness.idlife.com for more information.
Location, ST | website.com


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United States Department of Agriculture
Agricultural Research Service
Appalachian Fruit Research Laboratory
1a.Objectives (from AD-416)
Specifically, we will: (1) isolate and identify attractive olfactory stimuli associated with host- and mate-finding for adult plum curculio using gas chromatography coupled with electroantennogram detection (GC-EAD) and mass spectrometry (MS); (2) develop effective deployment strategies for newly identified olfactory stimuli to manipulate host- and mate-finding behavior and promote aggregation of the plum curculio within commercial apple orchards; (3) evaluate efficacy of entomopathogenic nematodes against PC larvae; (4) evaluate efficacy of a multi-life stage approach for management of PC within spatially precise locations within commercial apple orchards; and (5) actively promote outreach and information exchange among interested stakeholders, crop consultants, state IPM research and extension programs, and federal researchers.
1b.Approach (from AD-416)
We will utilize laboratory-based electrophysiological studies and field-based bioassays to identify novel olfactory stimuli for the plum curculio. We will also perform laboratory- and field-based studies to identify effective entomopathogenic nematodes. Final evaluations will be conducted in commercial orchards.
"Specialty Crops Research Initiative".
3.Progress Report


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Simple Definition of typify
: to represent what is normal for (something) : to be a good or typical example of (something)
: to have the usual characteristics of (something) : to be a typical part or feature of (something)
Full Definition of typify
1 : to represent in typical fashion : to constitute a typical mark or instance of <realism…that typified his earlier work — Current Biography>
2 : to embody the essential or salient characteristics of : be the type of
typificationplay \ˌti-pə-fə-ˈkā-shən\ noun
Examples of typify in a sentence
His heroic actions typified the courage of all the firefighters at the scene.
The decor typifies the elegance of royal residences.
He typifies what a professional athlete should be.
Gothic architecture is typified by soaring rooflines and stained glass.
First Known Use of typify
Rhymes with typify
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TYPIFY Defined for Kids
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About the Book
"[An] audacious concept. . . . [A] giddy thrill." —Los Angeles Times
"Weird? Obviously. . . . There's more than stuffing here, though, including questions of good vs. evil, life vs. death, and sanity vs. insanity. Skip that evening Scotch and read this one stone-cold sober—it's plenty trippy as is." —Washington Post on Amberville
A horrific crime sets off a disturbing chain of events in Tim Davy's Mollisan Town. Like George Orwell's Animal Farm, as well as the allegorical worlds of Neil Gaiman and Jasper Fforde, this sinister sequel to Lanceheim and Amberville illuminates our reality through a giddy paradoxical conceit—as in Tourquai, the stuffed animals who populate Mollisan Town will be forced to confront the deepest issues of love and servitude, free will and destiny, life and death.
A horrendous crime sets off a disturbing chain of events that will force the citizens of Mollisan Town to debate profound issues of free will and destiny in this powerful tale from the internationally acclaimed Tim Davys.
In the Tourquai neighborhood of Mollisan Town, Superintendent Larry Bloodhound is the keeper of the peace and ruler of the streets. But there are others more powerful than he—a cadre of wealthy elite, including Oswald Vulture, who live above the law's reach.
When Vulture is found headless in his ornate office atop Mollisan Town's most exclusive building, Bloodhound knows he must take special care in the investigation. But with the head missing and no sign of a break-in or murder weapon, this just may be the perfect crime.
The search for answers leads Bloodhound and his team, Anna Lynx and Falcon Ècu—along with his closest friend, private detective Philip Mouse—deep into the exclusive, secretive world of Mollisan Town's most privileged. Who had the most to gain from Vulture's demise? His slithery and sexy secretary, Emanuelle Cobra? Or his seductive mistress, Jasmine Squirrel? And what about Igor Panda, a desperate gambler whose debts may have pushed him to do the unthinkable? But before he can find the truth, Bloodhound must face his own weaknesses.
As he did in Amberville and Lanceheim, Tim Davys weaves an intricate plot around larger questions of human nature, exploring issues of fate, loyalty, good, and evil. As Bloodhound uncovers the secrets behind the world of stuffed animals, so, too, does Davys reveal greater truths about the world of humans.
Educator and Librarian Resources
Critical Praise
"The combination of stuffed animals and hard-boiled crime fiction is oddly compelling, and entertaining...The characters are fleshed out (plushed out?) with fallible character traits and secrets...Davys has created a unique place that is both strange and familiar." — Boston Globe
Product Details
- Imprint: Harper
- On Sale: 02/15/2011
- Trimsize: 5.5 in (w) x 8.25 in (h) x 1.09 in (d)
- Pages: 336
- List Price: 19.99 USD
- BISAC1: FICTION / General


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Ideal for upending, draining, moving, rotating and storing drums
This handy lift can be used for upending, draining, moving, rotating and storing 30- and 55-gallon drums. Oak handles telescope into channel when not needed. Rollettes permit horizontal drum to be rotated. Stand slides under drum for easy lifting. Drain height is 20". Rolls easily on 1-1/2"Wx5"-dia. polyolefin wheels. Orange color. Weighs 56 lbs. Shipped unassembled. USA made.NOTE: Not recommended for handling poly drums.
2016 Master Catalog: Page 548