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The Childhood and Adolescent Migraine Prevention Study (CHAMP)
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Migraine Disorders
Drug: Amitriptyline
Drug: Topiramate
Drug: Placebo
Phase 3
|Study Type:
|Study Design:
|Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Prevention
|Official Title:
|Amitriptyline and Topiramate in the Prevention of Childhood Migraine
- Reduction in Migraine Frequency (amitriptyline and topiramate) [ Time Frame: 4 week baseline period to last 4 weeks of the 24-week trial ] [ Designated as safety issue: No ]To test if amitriptyline and topiramate are superior to placebo in reducing migraine frequency, as defined by the percentage of subjects with a 50% reduction in the number of migraine days per month, in children and adolescents ages 8-17.
- Reduction in absolute migraine disability score on PedMIDAS [ Time Frame: 4 week baseline period to last 4 weeks of the 24-week trial ] [ Designated as safety issue: No ]To determine if amitriptyline and/or topiramate will result in a decrease in absolute migraine disability score (measured by PedMIDAS).
- Safety and tolerability of amitriptyline and topiramate [ Time Frame: 4 week baseline period to last 4 weeks of the 24-week trial ] [ Designated as safety issue: Yes ]
To determine if amitriptyline and topiramate are well tolerated, and safe for participants and their care givers.
Tolerability will be measured by a determination of the number of participants who are able to achieve the planned maximum dosage of the active study drugs without enduring dosage limiting side effects.
Safety will be measured by the quantitative review of adverse events for all three arms of the study in comparison with placebo and the adverse events profiles reported in the package inserts for the study drugs.
- Occurrence of treatment-emergent serious adverse events [ Time Frame: 4 week baseline period to last 4 weeks of the 24-week trial ] [ Designated as safety issue: Yes ]To determine if amitriptyline or topiramate differ from placebo on the occurrence of treatment-emergent serious adverse events.
- Reduction in absolute migraine frequency days [ Time Frame: 4 week baseline period to last 4 weeks of the 24-week trial ] [ Designated as safety issue: No ]To determine if amitriptyline and/or topiramate will result in a decrease in absolute migraine frequency days.
|Estimated Enrollment:
|Study Start Date:
|June 2012
|Estimated Study Completion Date:
|December 2016
|Estimated Primary Completion Date:
|July 2016 (Final data collection date for primary outcome measure)
|Assigned Interventions
Active Comparator: Amitriptyline
Drug to be administered twice daily.
Drug: Amitriptyline
Amitriptyline will be administered twice daily at home during the 8-week titration period. The morning dose is a placebo pill. Dosing of amitriptyline will be weight-based.
Active Comparator: Topiramate
Drug to be administered twice daily.
Drug: Topiramate
Topiramate will be administered twice daily at home during the 8-week titration period. Dosing of topiramate will be weight-based.
Placebo Comparator: Placebo
To be administered twice daily.
Drug: Placebo
Placebo will be administered twice daily at home during the 8-week titration period.
Detailed Description:
|Ages Eligible for Study:
|8 Years to 17 Years (Child)
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Migraine with or without aura (International Classification of Headache Disorders, 2nd Edition (ICHD-II) or chronic migraine (ICHD-II revised)
- Migraine frequency based upon prospective headache diary of 28 days must be ≥ 4. Migraine frequency defined as any migraine during one day in the 28 day baseline period (1)
- PedMIDAS Disability Score > 10, indicating at least mild disruption in daily activities and < 140, indicating extreme disability that may require more comprehensive, multi-component therapy
Females or males 8-17 years, inclusive
- Migraine frequency is defined as the period from the onset to the stop time of painful migraine symptoms not to exceed 24 hours with the clock starting at midnight. If painful symptoms last longer than 24 hours, this is considered a new and distinct migraine headache. If painful symptoms recur within 24 hours of initial onset, this is considered part of the initial migraine episode and would be counted as one migraine.
Exclusion Criteria:
- Continuous migraine defined as an unrelenting headache for a 28 day period
- Weight less than 30 kg or greater than 120 kg
- Unwilling to avoid taking non-specific acute medication such as NSAIDS (e.g., ibuprofen), more than 3 times per week, or migraine specific acute medications such as triptans more than 6 times per month
- Currently taking other prophylactic anti-migraine medication within a period equivalent to 2 weeks of that medication before entering the screening phase
- Subjects who have previously failed an adequate trial of AMI or TPM for prophylaxis of at least 3 months duration at doses recommended for migraine relief because of lack of efficacy or adverse events(2)
- Current use of disallowed medications/products: opioids, antipsychotics, antimanics, barbiturates, benzodiazepines, muscle relaxants, sedatives, tramadol, nutraceuticals, SSRIs, or SSNRIs
- Known history of allergic reaction or anaphylaxis to AMI or TPM
- Abnormal findings on ECG at baseline, particularly lengthening of the QT interval greater than or equal to 450 msec
- Subject is pregnant or has a positive pregnancy test
- Subject is sexually active and not using a medically acceptable form of contraception
- Diagnosis of epilepsy or other neurological diseases
- History of kidney stones
- Inability to swallow pills after using behavioral techniques if indicated between screening visit and baseline visit(3)
- Present psychiatric disease as defined by the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM IV) (e.g. psychosis, bipolar disorder, major depression, generalized anxiety disorder), alcohol or drug dependence, or documented developmental delays or impairments (e.g., autism, cerebral palsy, or mental retardation) that, in the opinion of the site investigator, would interfere with adherence to study requirements or safe participation in the trial
Any and all other diagnoses or conditions which in the opinion of the site investigator, that would prevent the patient from being a suitable candidate for the study or interfere with the medical care needs of the study subject
(2)"Previously failed an adequate trial of AMI or TPM" is defined as: dosage of 1mg/kg/day of AMI or 2 mg/kg/day of TPM; trial of at least 3 months duration; efficacy of having at least a 50% decrease in migraine frequency in response to drug therapy; or unable to tolerate taking the medication due to treatment-related side effects.
(3)Subjects who cannot swallow pills at the time of the screening visit will be given a training session using behavioral techniques. Upon return for baseline visit, if the subject continues to be unable to swallow pills, the subject will be excluded from the study.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01581281
Show 35 Study Locations
|Principal Investigator:
|Scott W. Powers, PhD
|Children's Hospital Medical Center, Cincinnati
|Principal Investigator:
|Andrew D. Hershey, MD, PhD
|Children's Hospital Medical Center, Cincinnati
|Principal Investigator:
|Christopher S. Coffey, PhD
|The University of Iowa
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|Children's Hospital Medical Center, Cincinnati
|ClinicalTrials.gov Identifier:
|NCT01581281 History of Changes
|Other Study ID Numbers:
|Study First Received:
|December 16, 2011
|Last Updated:
|February 16, 2015
|Health Authority:
|United States: Food and Drug Administration
Keywords provided by Children's Hospital Medical Center, Cincinnati:
Additional relevant MeSH terms:
Migraine Disorders
Amitriptyline, perphenazine drug combination
Headache Disorders, Primary
Headache Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurologic Manifestations
Signs and Symptoms
Neuroprotective Agents
Protective Agents
Physiological Effects of Drugs
Anti-Obesity Agents
Antidepressive Agents, Tricyclic
Antidepressive Agents
Psychotropic Drugs
Analgesics, Non-Narcotic
Sensory System Agents
Peripheral Nervous System Agents
Adrenergic Uptake Inhibitors
Neurotransmitter Uptake Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Adrenergic Agents
ClinicalTrials.gov processed this record on August 29, 2016


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The goal of the Indiana Multi-Agency/Multi Jurisdiction Computer Aided Dispatch/ Records Management System (CAD/RMS) project is to save money and save lives via a standards-based, shared data system accessible to all of Indiana's public safety agencies. Using funds from the federal Recovery Act, Indiana invested in a statewide CAD/RMS system - implementation and subsequent operation/maintenance are based on the highly successful statewide interoperable voice communication system:
For more information about CAD, RMS, Mobile and Jail Tracker, visit the Caliber/Interact website: https://caliberpublicsafety.com/

subset: commoncrawl


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Category:Swiss people
Free public domain sheet music from IMSLP / Petrucci Music Library
The following is a list of people represented on IMSLP from Switzerland.
→ Sort this list by composers, editors, arrangers, librettists, performers, time period and more.
This category has the following 124 subcategories, out of 124 total.


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8 (6 oz.) Marinated Salmon Fillets |
Our moist and flaky Atlantic Salmon fillets are marinated in a mixture of olive oil, garlic, paprika, onion, pepper, and natural grill flavor. This Salmon make a tasty meal that's oh, so easy!
Read what our customers say
fantastic flavor so easy to prepare can't keep enough in the house my family and friends love theseElizabeth M. - Bayonne, NJ
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- National Hispanic Heritage Month Home
- About
- Exhibits & Collections
- Images
- Audio/Video
- For Teachers
- Images Used On This Site
Brought to you by...
The following audio or video presentations are a sampling of the available material related to Hispanic American history available from the Library of the Congress and other partner agencies. These include Webcasts (taped recordings of presentations, lectures, performances and speeches that have taken place at the Library) as well as musical recordings and unique sound artifacts from our collections, such as the stories of Hispanic Americans.
Please note: This list represents only a selection of the digital and physical holdings of the participating agencies.
History and Culture
- Anthony Acevedo donates artifacts to the Holocaust Museum (United States Holocaust Memorial Museum on Facebook) (external link)
- The Art of Power: Royal Armor and Portraits from Imperial Spain (National Gallery of Art)
- An Examination of Hispanic and Latino History (National Archives YouTube Channel) (external link)
- La Quinceanera: A Coming of Age Ritual in Latino Communities (Library of Congress)
- Latino Americans – PBS Documentary (external link) (supported by the National Endowment for the Humanities)
- Mexicans and Americans: Cracking the Cultural Code (Library of Congress)
- Nation and Citizen in the Dominican Republic, 1880-1916 (Library of Congress)
- Professor Ilan Stavans, Professor of Latin American and Latino Culture, Amherst College (Holocaust Memorial Museum)
- Re-thinking Conquest: Spanish and Native Experiences in the Americas (Library of Congress)
- The Storm that Swept Mexico (external link)
A collaboration between the National Endowment for the Humanities and PBS, this film tells the gripping story of the Mexican Revolution of 1910, the first major political and social revolution of the 20th century.
- StoryCorps Historias (external link)
StoryCorps Historias is a project to record the diverse stories and life experiences of Latinos in the United States. StoryCorps is a project of Sound Portraits Productions, in partnership with National Public Radio and the American Folklife Center at the Library of Congress.
- When Worlds Collide (external link)
A collaboration between the National Endowment for the Humanities and PBS, this film traces the origins of today's Latin culture and documents the collision between the Old World and the New World.
Music / Performing Arts (Library of Congress)
- California Gold: Northern California Folk Music from the Thirties (Collection)
- Hispano Music and Culture of the Northern Rio Grande: The Juan B. Rael Collection
Past Hispanic Heritage Month Keynote Addresses (Library of Congress)
- 2006 Keynote Address: Alberto Gonzales, United States Attorney General
- 2003 Keynote Address: Richard H. Carmona, Former U.S. Surgeon General
Poetry & Literature (Library of Congress)
- 450 Years of Spanish Poetry in the United States
- Burnt Sugar Cana Quemada
- Poetry Readings from Clayton Eshleman and Gonzalo Corzo
- Red Hot Salsa: Bilingual Poems on Being Young and Latino in the United States
- Spotlight on U.S. Hispanic Writers
- Teatro de la Luna Poetry Marathon (2008)
- Teatro de la Luna Poetry Marathon (2011)
Politics and Government (Library of Congress)
- The Need for Global Democratic Governance: The Perspective from Latin America
- Prime Minister of Barbados: Owen Seymour Arthur
- Tiburcio Carias: Portrait of a Honduran Political Leader


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41 Opinions
New version of Safari already has this function. It's not as pretty as Inquisitor but having less plugins in Safari means more stability.
Does it work for other web browzers such as Firefox?
I just got a brand new MacBook Pro 2008 (gloating). and since it could not be any newer decided to try out Inquisitor 3.2 (56) again. Sure enough... its broken beyond hell and will not accept any search engine other then Yahoo! for the completion list.
However... the good news is that on build 58.... other search engines do work. Go Figure!!!!
So... for those of you with this problem.. simply update to 3.2. (58) and all will be okay.
Recently Inquisitor has started to freeze safari completely after a few searches. It doesn't just freeze, becuase before this happens Safari is extremely slow as well. It did it so much that I had to switch back to Firefox as Safari would effectively become unusable.
After looking up "inquisitor freezes safari" in google, I found that LOTS of people have this problem and they all had Inquisitor installed.
I have since completely uninstalled it and Safari is lightning fast again :D
I am going to switch to either AcidSearch or Glims now.
P.S. To uninstall this completely, you have to trash the following:
Inquisitor.bundle (in Library/InputManagers/Inquisitor/)
Inquisitor folder (in "user=you"/Library/Application Support/)
inquisitor.pkg (in Library/Receipts/)
inquisitorPreflight.pkg (also in Library/Receipts/)
inquisitor folder (in Library/InputManagers/)
I have replaced this + Saft with Glims. So much happier.
I'm a little skeptical about the Yahoo-thing as well (though I'm "happy" for the author), but I DO get suggestions for Google as I did before.
Nothing suspicous so far, still works like a charm.
Using latest version and I've changed my search to Google and I get site suggestions fine. David Watanabe has stated that no crippling will be done for non-Yahoo search engines.
I recently did an update of Inquisitor... and I too suffered from the non-Yahoo! crippling. I am 1000% offended by the mis-trust. So until they correct this I will NOT use this product. Good Going Yahoo! - what a way to slap us in the face.
new version tries to phone home after installing process finishes
Avoid. Keeps a cache of icons at ~/user/application support/inquisitor. Essentially makes your search history visible to anyone using spotlight. Try out Glims. It's more customisable and doesn't appear leave files on your system either.
Page 1 of 5. 41 entries.


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Eight people are looking for new homes after a fire ripped through their five apartments.
The four-alarm blaze broke out a little before 5 p.m. Sunday at the corner of Esplanade and North Villere.
Fire investigators say a man was on the third floor when the fire started and was able to get out safely.
Eighty-two firefighters fought the blaze as strong winds fanned the flames.


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Drinking soda is so last decade. Well, actually according to a Gallup poll released this July, 48 percent of Americans drink at least one glass of soda per day. But this statistic hasn't stopped a crop of healthier beverage alternatives from popping up in the last few years, attempting to replace coffee and soda as our preferred daily drinks. There are a slew of new liquids on the market, many promising to provide nutrition through supplements and additives. This year the buzzwords on everyone's lips about what the liked to sip are "kombucha," "chia" and "probiotics."
Kombucha is a fermented tea containing amino acids, probiotics and anti-oxidants. High Country Kombucha is made locally in Eagle and sold nationwide. Owner and founder Edward Rothbauer said he started drinking kombucha in the early '90s after becoming paralyzed from a construction accident. He acquired a live culture and started making kombucha at home. Rothbauer believes drinking kombucha helped him recover from his accident and get movement back in his lower region. Rothbauer started High Country Kombucha in 2004 and now the company produces 65,000 cases of kombucha every month.
There are few U.S. studies showing a direct link between drinking kombucha and preventing disease.
Rothbauer said there is research being done in Europe and Asia showing kombucha "protects you against gamma radiation, is anti microbial (and) will build your immune system against any pathogens."
"Locally, I know a lot of people that won't go a day without it because it helps with gout," Rothbauer said. "Right now (kombucha) is being used widespread as a wellness supplement. The people that do drink it understand the benefits."
Not everyone in the alternative health business is a fan of kombucha. Dr. Andrew Weil, well known writer and teacher of holistic health, does not see any health benefits to drinking kombucha and warns against toxins that could arise when making homemade brews of the tea. Eagle Naturopathic doctor and acupuncturist Eliza Klearman thinks kombucha is a healthy drink someone could add to their diet if they wanted to.
"I'm definitely more open to it than (Dr. Weil)," Klearman said. "I would recommend that people drink kombucha ... You have to be careful with how it's brewed, but I think it's a great addition to someone's repertoire when it comes to health."
Gypsum resident and senior at Eagle Valley High School Isaac Burnham started drinking kombucha about a year ago after a friend introduced him to it. Burnham said he now drinks kombucha daily and feels it gives him more energy when running for track and cross country.
"I used to drink a lot of Red Bull, which was very unhealthy," Burnham said. "After drinking Red Bull I would crash and it would make things worse. Now I drink (kombucha) to rejuvenate. It affects your mood too. When you drink it, you know that you're drinking something healthy, so your mood is better."
Another popular drink additive on the market is chia seeds. Brands like Mamma Chia claim to contain high doses of omega-3 fatty acids and be a good source of fiber and antioxidants. Chia seeds are replacing flax seeds as the "it" seed to add to both beverages and baked goods. Klearman said chia seeds are high in fiber and omega-3s, which most people need more of in their diet.
"If there were any supplement I would recommend anybody take, it would be omega-3 fatty acids," Klearman said. "(Omega-3s) are used for every function in the body. They help maintain cell walls, they're really important for brain and neurological functions and they're anti-inflammatory. All diseases start with inflammation and (omega-3s) have that anti-inflammatory component."
Klearman said there are two main types of omega-3 fatty acids, DHA and ETA. Chia seeds are a good source of ETA but not DHA.
"Chia seeds, eating them or drinking them, are great to add into your diet," Klearman said. "But (chia seeds) are not going to replace fish. They're not going to really even replace the need for a good quality fish oil supplement."
Yogurt-based probiotic drinks are also becoming more prevalent. Probiotics contain healthy bacteria and yeast that aid in digestion. Klearman said while probiotic drinks do help with digestion, certain yogurt-based drinks can be loaded with sugar or high fructose corn syrup, which counteracts the benefits.
"I don't think it's bad to eat yogurt," Klearman said. "But I'm fairly picky about what kind of yogurt I want people to eat. (I recommend) whole milk plain yogurt. Making your own fermented foods, like making your own yogurt, is always going to be better than what you can find in the grocery store."
Klearman said the most important thing to remember is that no healthy drink can replace the benefits of eating a well-balanced diet.
"Make sure it's a part of a whole, healthy diet, not just 'I'm drinking my chia seeds,'" Klearman said. "People don't realize that by eating the right foods, we can have an effect on our health."
It's still unclear if the benefits of drinks with nutritional additives will live up to the hype in the long run. But as long as people keep buying them, the trend towards drinks that help rather than hinder your health is here to stay.
"I actually had the former CEO of Budweiser tell me that kombucha was going to be 'the beer of the 21st century,' because of what he felt was people moving toward a healthier (lifestyle)," Rothbauer said.
Perhaps kombucha will never surpass beer, currently America's most popular alcoholic beverage. But just like beer, it does have an acquired taste that tends to grow on people the more they drink it.


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text:
SANTA CLARA -- Striving to force more turnovers, the 49ers defense has created rubber bracelets as a reward. They read: "To It = See It = Get It."
NaVorro Bowman coined that phrase and unveiled one such trophy on his left wrist in advance of their "Takeaway Thursday" practice. "We try to pride ourselves on defense with going after turnovers," Bowman said. "If you do that, you give your team a better chance to win."
Remarkably, the 49ers (9-3-1) have been winning without a cluster of takeaways. Opposing rushers haven't lost a fumble in their past 249 carries, a drought dating back to Toby Gerhart's two fumbles that Ahmad Brooks forced on Sept. 23 at Minnesota.
"We've just got to hit people hard," Brooks said. "Today is 'Takeaway Thursday,' so a lot of guys will be trying to strip the ball."
The 49ers haven't intercepted a pass in their past two games, or in the 92 passes they've faced since Brooks and Donte Whitner returned interceptions for touchdowns at New Orleans on Nov. 25.
On Sunday night, they'll face a New England Patriots team that's committed a league-low 10 turnovers, with five interceptions and five fumbles. Running back Stevan Ridley has lost one fumble in 243 carries (1,082 yards), and quarterback Tom Brady has lost none.
Defensive coordinator Vic Fangio called the Patriots' ball security amazing, adding: "They're a high-octane offense, yet they haven't turned the ball over hardly at all this year. So, when you put those two things together, that's why they're a tough assignment."
Offensive coordinator Greg Roman said he became versed in the pistol formation by visiting Nevada's coaches before the 2010 season while Roman was assisting at Stanford. "That was very valuable time spent," said Roman, who recalled Kaepernick looking "productive" on the films he reviewed.
For each sack this season, Smith announced he will put $5,099 toward the Boys & Girls Clubs in San Francisco and East Palo Alto. He is three sacks shy of Michael Strahan's single-season league record of 22½.
"We are thrilled to be Aldon Smith's charity of choice and greatly appreciate his generosity," said Rob Connolly, president of Boys & Girls Clubs of San Francisco.
Launching the craze, Kaepernick retweeted a fan's picture of his pose with the superimposed headlines: "Score a touchdown. Kiss your tattoo! #KAEPERNICKING." Kaepernick attached a personal message to that image: "Love my tats, even if you don't."
For more on the 49ers, see Cam Inman's Hot Read blog at blogs.mercurynews.com/49ers. Follow him on Twitter at twitter.com/CamInman.


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PIKEVILLE, Ky. – Ninth-ranked University of Pikeville blistered the nets for 59.7 percent shooting and knocked off Shawnee State University 90-71 Thursday night at the East Kentucky Expo Center.
Six Pikeville players reached double figures in the game and the home team was credited with 27 assists in the win.
Pikeville (10-1 overall, 3-1 in the Mid-South Conference) trailed early after Shawnee State opened up with the first five points. It led 11-7 after freshman Nick Gouch scored on a layup. He had eight of his team's points at that juncture with 13:32 to play.
From there, though, UPIKE scored 13 unanswered points. Senior guard Chris Johnson had five in the stretch while senior guard Trevor Setty added four, and when senior guard Jamar Briscoe flipped in a layup with 9:37 left to give him 12 early markers, Pikeville's lead was 20-11.
Pikeville led by 24 twice in the second half before settling for the 19 point margin.
Junior guard Darnell Tubbs paced all scorers with 19 points, leading the bench to 29 in the contest.
The other five double-figures were starters. Setty flipped in 16 while Johnson and Briscoe had a dozen each. Senior forward Terrance Saintil added 11 while junior guard Josh Whitaker flipped in 10.
Johnson added seven assists for the home team while Whitaker and Tubbs tossed out four each.
Junior Brandon Greene came off the bench for 10 rebounds and the nation's leading shot-blocker had two in only 15 minutes of action.
Shawnee State (4-3, 2-1) had one player score double figures as senior Tyler Morgan scored 14 while pulling down 12 rebounds.
The guests had 10 players score and 15 see action in the loss. They sank all 10 of their free throw shots in the game.
Pikeville will remain home on Saturday when it hosts Rio Grande at 4 p.m. Shawnee State will head across the state line to visit U.Va.-Wise at 4 p.m. Saturday.


text:
Southside Drive to be closed for two months
Published: Sunday, March 3, 2013 at 3:30 a.m.
Last Modified: Sunday, March 3, 2013 at 11:32 p.m.
TUSCALOOSA | The Tuscaloosa Department of Transportation says John Plott Co. will be closing Southside Drive beneath the Interstate 359 overpass on Monday for two months. The closure is due to major drainage construction.
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.
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The Moundridge High School Volleyball team went 1-1 to open up the season, picking up a win against Conway Springs and then falling to Hesston in a Triangular Tuesday at MHS.
The Wildcats defeated Conway Springs in straight sets 25-15, 25-20. Moundridge started slow on the blocking game, but picked up by the end of the game, according to head coach Kelsi Chisholm. The Wildcats then started off down to Hesston, but kept competing before falling 19-25. The second set saw Moundridge get down 8-1, which was too much of an obstacle to overcome and they fell 11-25.
"Hesston played well and we couldn't get momentum," Chisholm said.
Brooke Holloway led the team with 14 kills, followed by Mackenzie Suderman and Michelle Schrag, who both had 12.
The Wildcats play Saturday in the Inman preseason tournament. Their first match is against Sedgwick at 9 a.m.
Location, ST | website.com


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Brought to you by and the .Vail official report: 0" new snowVail Daily field report: There's a half inch or so of new snow on the ground.Weather: Overcast, snowing slightlyLiftline status: Not badRun of the day: Anything on Golden PeakBreakdown: With 100 of the best snowboarders in the world in Vail for the Burton US Open, we really lucked out with beautiful weather to welcome them into town yesterday. Today is overcast for day 2 of halfpipe and slopestyle practice, but there's a few snowflakes falling so hopefully with the cloudy skies will come fresh snow for Wednesday. Snowcast: We're supposed to get a couple inches today/tonight, forecasters say.
On the Hill is shot with a GoPro HERO3 Silver Edition.


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So much for my sewing plans; what I forgot when I came up with my timetable was that I was seeing a friend yesterday and needed to sort out the embryonic herb garden my parents gave me for my birthday today, and that as a gardening novice that was almost certainly going to use up most of my energy for today.
Still, after a trip to the garden centre for pots, potting compost and a watering can, and an hour or so's potting (not to mention a fun few minutes smashing a roof-tile up with a hammer so I could put the shards in the bottom of the pots to aid drainage), I have a rather nice little herb garden:
That's bay, chives, mint, rosemary, fennel and sage (more or less from top to bottom). Some thyme might be good, but that seems like a pretty good start.
My mother also gave me two rose campions which I've put on either side of the back door.
I think they'll look lovely when they've grown enough to flower.
The friend I saw yesterday also gave me a sweet little bag designed to look like a vintage sewing pattern:
I think it's rather fun.
I think it was really supposed to be a make-up bag, but I don't wear make-up; my first thought was to keep knitting or sewing oddments in (if there's one thing I've learned over the years, it's that you can never have too many little bags to keep bits and pieces in) but then it struck me that it looked as though it was a very similar size to the Kindle I'd just been eyeing up in Curry's. I love paper books, and have a house full of them (quite a lot of which I haven't read yet, and at least some of which I suspect I'll never read), but over the last few months I've discovered a lot of advantages to ebooks; they're obviously particularly good for holidays or travel, but they also stop me from falling into my usual bad habit of reading in bed when I'm really too tired to concentrate and flipping idly forward through the pages, until I find I've skim-read the whole book and lost interest in finishing it properly. Until now I've been reading on my iPad and occasionally on my phone, but the iPad is a bit cumbersome and certainly not something I'd take out and about regularly, while the phone is a bit on the small side for comfortable reading, so I had been wondering about a Kindle. And when we went back to Curry's we could see that the case was exactly the right size for it; I had to remove the zip (discovering in the process that my seam ripper appears to have vanished – see what I mean about needing little bags to keep bits and pieces in?) to get the Kindle in, but once I had done it fit like a dream.
(And if you recognise what I'm reading, you'll see another reason why ebooks are such a good idea – I haven't re-read it for far too long, because lugging our one-volume paperback around is far too tedious.)


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Holidays Come Early for Accel Partners
Accel Partners got a pair of early Christmas presents last week.
First, eBay Inc. finalized its $800 million acquisition of the mobile payments platform Braintree, which lets people pay each other using mobile devices.
Braintree had raised about $70 million in funding, and Accel was its first institutional investor. The firm in 2011 provided a $34 million Series A round, installed a new chief executive (Bill Ready, a former Accel executive in residence) and ultimately invested about $40 million in Braintree for a 40% stake, which generated a return of nearly 8x, according to a person familiar with the deal.
Then Dealertrack Inc. agreed to acquire Dealer.com Inc. in a deal valued at about $1 billion so the two companies could join forces to automate the automotive retail industry.
Accel Partner Rich Wong declined to specify Accel's return, but said the firm had invested about $39 million in Dealer.com and held a minority stake. (Another beneficiary of this deal is Apax Partners, which acquired a stake in Dealer.com through its purchase of Trader Corp.).
Mr. Wong also points out that Accel still holds a stake in Nimble Storage Inc., which went public last week and now has a market cap of more than $2.6 billion.
Nimble's shares rose more than 60% on the first day of trading, which was December 13, and have continued to rise, closing on Friday at $37.50. Accel's post-IPO stake, according to regulatory filings, is 18.4%.
Write to Deborah Gage at firstname.lastname@example.com. Follow her on Twitter at @deborahgage


text:
3.3-3 Statute of
Limitation Defense - Tolling
Revised to January
1, 2008
law recognizes that there are some
situations in which the period set in a
statute of limitation does not apply, or
in which the date when the period begins
to run is suspended or delayed. These
situations are referred to as "tolling"
the statute of limitations. The time
specified for bringing suit does not run
during a time when the statute of
limitations is tolled.
The plaintiff
has alleged that one [or more] of these
situations is present, and that the
statute of limitation therefore does not
apply in the way the defendant asserts.
The plaintiff has the burden of proving
that the statute of limitation is tolled
for the reason that (he/she) asserts.
Continuing course of conduct
The statute
of limitation is applied differently if
the incident on which the claim is based
is part of a continuing course of
conduct between the parties. The
plaintiff has alleged that <describe
claim> was not an isolated
transaction but was part of a continuing
course of conduct in which the defendant
engaged over a period of time. To
establish a continuing course of
conduct, the plaintiff must present
evidence that the defendant assumed a
duty that remained in existence after
commission of what is alleged to be the
original wrong committed against the
plaintiff. If the incident at issue in
the suit was part of a continuing course
of conduct, then the plaintiff may
prevail on claims resulting from any act
that was part of that continuing course
of conduct, even if the particular act
was outside the ___ year limitation
period. If the incident was not part of
a continuing course of conduct, but a
separate instance of the defendant
undertaking a duty that ended with the
completion of the transaction, the
plaintiff cannot prevail on claims based
on those incidents that were not brought
within ___ years of bringing suit.
In deciding
whether there was a continuing course of
conduct, you must determine what duty
the defendant assumed, and when that
duty terminated. The fact that parties
may in fact have engaged in additional
transactions at a later date may be
evidence of a continuing course of
conduct, or it may be evidence only of a
series of separate transactions,
depending on what duty you find the
defendant assumed in each transaction.
You must decide whether the plaintiff
has proved that the conduct that
occurred outside the time limit for
bringing suit was or was not part of a
continuing course of conduct.
Even where
there is a continuing course of conduct,
the plaintiff's claim is barred if
(he/she) failed to bring (his/her) claim
within ___ years of the most recent part
of that course of conduct.
Grey v.
Stamford Health System, Inc.,
282 Conn. 745, 751-56 (2007);
Blanchette v. Barrett, 229 Conn.
256, 275-77 (1994); Fichera v. Mine
Hill Corp., 207 Conn. 204, 209
B. Special
The plaintiff
has alleged that even though some of the
acts on which (his/her) claims are based
happened more than ___ years before
(he/she) brought suit, they are not
barred by the statute of limitation
because the acts arose from a special
relationship between the parties that
required the defendant to act in
accordance with a continuing duty of
care toward the plaintiff. The
existence of a special relationship must
be proved on the basis of the facts.
You must determine from the facts
whether the defendant had assumed a
relationship of trust and continuing
duty toward the plaintiff that continued
past the date of the incident on which
the claim is based. The fact that a
plaintiff may have had a special
relationship with the defendant (as
_____) at one point in time does not
necessarily establish that there was an
ongoing relationship. It may be that
the parties had a special relationship
that ended, or a series of times or
transactions when the defendant had a
special relationship with the plaintiff
that was not continuous but ended with
the completion of each transaction. If
the defendant had a special relationship
with the plaintiff that required
(him/her) to <describe>, then a
claim is not barred by the statute of
limitations if the plaintiff brought
suit within ___ years of the last date
on which that special relationship
existed. You must consider all the
facts to determine whether the plaintiff
has proved that the defendant assumed a
special relationship with the plaintiff
that subjected (him/her) to a continuing
duty to act in the plaintiff's best
Zielinski v.
279 Conn. 312, 322, 330 (2006);
Blanchette v. Barrett, 229 Conn.
256, 275-76 (1994); Fichera v. Mine
Hill Corp., 207 Conn. 204, 210
Fraudulent concealment
The statute
of limitation period is tolled and does
not bar a claim if the plaintiff proves
that for all or part of the period the
defendant fraudulently concealed the
cause of action from the plaintiff. To
establish fraudulent concealment, the
plaintiff must prove all three of the
following things: 1) that the defendant
was actually aware of facts necessary to
establish the plaintiff's claim; 2) that
the defendant intentionally concealed
those facts from the plaintiff; and 3)
that the defendant's purpose in
concealing the facts was to obtain delay
on the plaintiff's part in filing a
lawsuit based on the incident. If the
plaintiff has failed to prove any of
those things, then (he/she) has failed
to prove the elements necessary to
suspend the application of the statute
of limitation.
The proof
required on this issue is greater than
for most issues in a civil case. The
standard of proof for fraudulent
concealment is not simply "more likely
so than not so"; rather, the plaintiff
must prove fraudulent concealment by
clear, precise and unequivocal evidence.
A party from
whom a claim has been fraudulently
concealed must bring the claim within
___ years of the date when (he/she)
discovered the facts that give rise to
the claim, even if (he/she) proves that
the defendant intentionally concealed
those facts.
Statutes § 52-595; Falls Church
Group, Ltd. v. Tyler, Cooper & Alcorn,
LLP, 281 Conn. 84, 105 (2007);
Bartone v. Robert L. Day Co., 232
Conn. 527, 533 (1995); Connell v.
Colwell, 214 Conn. 242, 250-51
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text:
Barbs of racism, anti-Semitism in NY school clash
SYMBOLIC STAND–Supporters of public schools turn their backs on the East Ramapo school board during a meeting on March 19, in Spring Valley, N.Y. Allegations of racism and anti-Semitism are afflicting the district, where the board is dominated by ultra-Orthodox Jews and the public school children are mostly Black and Hispanic. (AP Photo/Jim Fitzgerald) by Jim Fitzgerald Associated Press Writer SPRING VALLEY, N.Y. (AP) — School board meetings descend into shouting matches. Accusations of racism and anti-Semitism fly. Angry parents turn their backs on board members in a symbolic stand of disrespect.


text:
Elizabeth (Liz) Newfield, 71, of Williams, Ore. passed away Wednesday, April 24, 2013 with her friend, Terry Canavello, and daughter, Mary Holmbeck, at her side.
A potluck celebration of Liz's life will be held at 2:00 p.m., Sunday, May 19, 2013, at the Greyback-Brushriders Clubhouse, Davidson Road, Williams, Ore.
To send an online condolence to the family go to www.grantspassfunerals.com.
Location, ST | website.com


text:
There were 63 bookings at the San Joaquin County Jail in the 24 hours ending at 8 a.m. Thursday. At that time, there were 1,386 people held at the jail, which has an official capacity of 1,411.
Weapons arrest: Community Response Team officers conducted a traffic stop near Hazelton Avenue and McDonnell Avenue about 10:20 p.m. Wednesday. Inside the vehicle, they found crystal methamphetamine and a loaded, stolen handgun, officers reported. Juan Solorio, 21, and Christian Elizondo, 23, were arrested on suspicion of numerous crimes, including drug possession, drug sales and unlawful possession of a firearm.
The California Highway Patrol responded to 13 noninjury accidents and three injury accidents in the 24 hours ending at 8 a.m. Thursday.
The Stockton Fire Department responded to 90 calls for service in the 24 hours ending at 8 a.m. Thursday, including three vehicle accidents, 75 medical calls and two structure fires.
Location, ST | website.com


text:
Friday March 22, 2013
KANSAS CITY – The Southeast Regional champion University of South Carolina Aiken men's basketball team is featured heavily on the 2013 National Association of Basketball Coaches (NABC) Division II Southeast All-District Team.
The NABC released the All-District Teams on Friday, March 22, 2013. The team was selected and voted on by NABC member coaches in NCAA Division II. The 89 student-athletes, from eight districts, are now eligible for the NABC Coaches' Division II All-America teams, selected by the NABC.
Back-to-back Peach Belt Conference Coach of the Year Vince Alexander was tabbed as the Coach of the Year in the district.
Peach Belt Conference Player of the Year, Peach Belt Conference Tournament Most Valuable Player and NCAA Southeast Regional Most Outstanding Player Re'mon Nelson was tabbed to the Southeast All-District First-Team. The senior guard was joined on the First-Team by junior forward Paul Larsen.
Now a two-time district Coach of the Year, Alexander has turned the Pacer men's basketball program into a national power over the course of the last six seasons.
Alexander became the all-time wins leader for the USC Aiken men's basketball program in the Pacers' 108-79 road win over Francis Marion on Monday, Dec. 17, 2012. Alexander is now 239-166 all-time in 14 seasons as a head coach. The eighth-year head coach is 150-92 as the head coach of the Pacer men's basketball team.
Alexander has guided USC Aiken to historic heights during his time in charge. In 2007-08, USC Aiken reached the national rankings for the first time ever before ending the year by winning the Peach Belt Conference regular-season crown. The Pacers, who won a school-record 27 games in the 2007-08 season, were the top seed in the NCAA Division II South Atlantic Regional during the 2007-08 campaign. Alexander was chosen as the 2007-08 South Atlantic Region Coach of the Year in addition to claiming conference Coach of the Year plaudits.
Alexander guided the 2008-09 Peach Belt Conference men's basketball team to its first-ever "Sweet Sixteen." One year later in the 2009-10 season, USC Aiken claimed the Peach Belt Conference Tournament Championship.
USC Aiken has now claimed back-to-back Peach Belt Conference regular-season championships (2011-12 and 2012-13) for the first time in program history.
In the midst of the best season in program history, the 2012-13 season under the guidance of Alexander has seen the Pacers win the Peach Belt Conference regular-season title, the Peach Belt Conference Tournament title and the NCAA Division II Southeast Regional crown.


text:
Cap about 120 M
$94,254,126- does not include Wragge and McDonalds contract or 8 of the 10 rookies whose numbers were not available, the rookies pool number for the niners amount to a max of aprox. 6.9mil total.
Dead money
Unknown whether they count against the 2011 cap
Glen Coffee- $414,122K
Brandon Jones- $2,100,000M


text:
Some changes are being made in my preparation.
Firstly I've begun consulting a professional for advice on my running technique and training tips for Goruck. Hi Sarah! I'm confident that this will greatly reduce my risk of injury and most importantly keep my head in the game during the run. Technique is a big focus for me as well, but as my trainer pointed out, with the weight I'll be carrying I won't be able to worry too much if at all about maintaining perfect form.
I buckled, finally, and got another pair of shoes to be used in training and for the event itself. They are New Balance 890s and I knew I wanted them the moment I took them for a jog outside the store. The fact that they are neutral will help me develop my own sense of my form and not over-influence me in one direction. The weight of the shoe makes a huge difference as well. I was used to trudging along in my RocLites by inov8 which weigh in at 312 grams, or about 11 ounces. The 890s are 9.7 ounces which doesn't seem like a big difference, but it's definitely noticeable. The New Balance website does a good job of illustrating the difference a few ounces can make in the long run--pun very much intended. So my old RocLites will be set aside for trail running and my 890s take the forefront. The only thing left to do is see how they perform in the rain and submersion to judge water-retention, and then to finally break them in after another 15 miles or so.
Speaking of mileage, here are the data from today's run:
My heart rate was generally under control and I felt light and strong for the majority of the run. I wasn't experiencing cardiovascular exhaustion by the end of the run, my desire to stop came mostly from muscle soreness. I did buy a foam roller from the running store as well, so I'll be using that often.
Tomorrow will be a light calisthenic/recovery day then I expect I'll do a light run (4-5 miles) on Friday. My trainer suggested I do 4-5 mile runs on Monday and Friday, and a longer run on Wednesday (6-7 miles) and then progressively increase the Wednesday mileage to a point while keeping the Monday/Friday distance the same. I'm still planning on a weighted run on the weekend, but I might substitute that for some weighted lunges around the block since that seems to be particularly important.
The training advancement of one Marauder in his quest to dominate the Tough Mudder.
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text:
ARLINGTON, Texas -- Jason Hammel is 0-3 in his first three starts for the A's after taking the loss in Oakland's 4-1 defeat to the Texas Rangers on Friday, so it's natural that the name "Tommy Milone" has started to pop up.
Milone was 6-0 with a 2.62 ERA over his previous 11 starts when he got sent down to make room in the rotation and on the Oakland roster for Hammel, who arrived with pitcher Jeff Samardzija in the July 4 blockbuster trade with the Chicago Cubs. Hammel was 8-5 with a 2.98 ERA for Chicago, but he has a 7.11 ERA with the A's, and his reputation for having above-average command has suffered a bit.
All of that is outside the A's clubhouse, mind you. Inside, the players and manager Bob Melvin see Hammel as a boost to the rotation and the roster, these three losses notwithstanding.
"His stuff is there," veteran shortstop Jed Lowrie said after the first-place A's fell to 63-39. "There were a couple of mistakes they took advantage of tonight. I know he's frustrated about it.
"This is a guy who has always been really effective. I think he'll start locating that stuff soon."
Melvin said this start was the best of the three for Hammel, who gave up single runs in the second and third innings, then held the Rangers there until Oakland pulled within a run on Yoenis Cespedes' RBI single in the sixth. Hammel immediately got dinged for two more runs, one unearned.
"It was a better mix for me," Melvin said. "After the first couple of innings, he got the ball down and commanded his fastball better. At times he had a really sharp slider tonight."
So, no, there won't be a quick call to Sacramento to get Milone, who is 1-0 with a 5.40 ERA in three starts for the River Cats. Asked how safe Hammel's job was, Melvin made it clear changes are not being contemplated.
"We traded for him for a reason," Melvin said of Hammel. "He's had a lot of success. We expect him to."
If anything, the performance of the A's offense against Rangers starter Jerome Williams was more surprising than Hammel's struggles. The lineup Melvin put together was a combined 36 for 90 (.400) lifetime against Williams. And in the last month, the veteran had been released by one last-place team (Houston) and picked up by another (Texas). He'd made two starts at Triple-A with an ERA of 6.10.
So when he went out and dominated the team that leads the majors in runs scored, it was at the very least counterintuitive.
"He's a veteran guy and he's smart," A's batting coach Chili Davis said. "He doesn't have the name, but he can sit up there (throwing) 92, 93 mph, and he's got a good changeup and a couple other pitches to go with his fastball."
Hammel wasn't as troubled by his stuff as he was by his execution.
"The easiest thing to do here is to get down on myself, but I'm not going to do that," Hammel said. "There were a couple of times when I needed to make a quality pitch. I've got to do better with quality pitches, make my misses down."
Hammel didn't get much help from his teammates. John Jaso tried to go from first to third on Cespedes' RBI single in the sixth and was thrown out. And Cespedes' throwing error set up the Rangers' final run.
A's (Sonny Gray 11-3) at Texas (Nick Tepesch 3-6), 5:05 p.m. CSNCA