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It doesn't look like things are looking good for #RyanLochte after lying about being robbed at gunpoint in #Rio. Despite apologizing on social media and via an interview with #MattLauer, Lochte is…Continue
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The #WallStreetJournal reports, today, #KobeBryant is launching a venture capital fund with investor #JeffStibel.The $100 million dollar fund will invest in media, data and technology companies. The…Continue
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5 Love Lessons From the Latino Couples That Know How to Show the Love
Until a guy says he wants to be exclusive (and you feel the same way), you have the right to play the field. For all you know, he's doing the same thing. Until you have The Talk, there's no reason to tell him you're seeing someone else.
In order to make a good decision, you need to be able to do your own thing. So don't tell either guy where you are all the time. If they're clued in to what you're doing 24/7, it's going to be harder for you to have the space you need to decide on one.

subset: commoncrawl


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URBANA, Ill. – Sophomore Peter Nagy of the Texas A&M-Corpus Christi men's tennis team will take on Mississippi State's Malte Stropp in the opening round of the 2013 NCAA Men's Singles Championship Wednesday at 10:30 a.m. at the Atkins Tennis Center, it was announced today. Nagy, ranked 88th in the nation, is the first Islanders individual to compete in the NCAA Championship. Stropp is currently ranked 57th nationally.
"This is huge, it's the NCAA Championships, the big dance, and we get to see Islanders Athletics in both the team tournament and the singles," Director of Tennis Steve Moore said. "You look at all the big-name schools in the draw, and there's A&M-Corpus Christi. I love our school and I love our city, so it means a lot to me personally to see us get exposure on the biggest stage."
Moore felt Nagy's work ethic was the key component to him reaching the NCAA Tournament and will be the key component in his match tomorrow.
"Peter has worked so hard and his consistency and tenacity in the way he's played earned him this ranking and this spot in the national tournament," Moore added. "Those will be the same keys that we rely on tomorrow. He's one of the elite competitors in the country and he's going to have a great chance to show that.
"It's hot and it's windy right now, and that plays into our style," he continued. "We've got a ton of respect for Mississippi State, but we'll do what we always do and try to focus on the things we can control and out-compete the other guy, one point at a time – play each point separately and with intensity. That's what our program is about and it's certainly what we want to represent on a national stage."
The singles championships, hosted by the University of Illinois, will continue with one round per day through May 27. A live video stream will be available for all of tomorrow's action at FightingIllini.com.
Nagy, a native of Budapest, Hungary, has lost just four matches between the fall and spring seasons, going 16-3 in dual matches in the spring, and losing just once during the fall at the ITA Texas Regionals. He won the Marco & Co. Islanders Open and the Rice Galleria Fall Invite, both ITA-sanctioned events, while reaching the Round of 16 at the ITA tournament. He has lost just once since Feb. 21.
Nagy was an automatic qualifier from the Southland Conference after winning the conference championship at No. 1 singles and being ranked in the top 125 singles players in the nation. He was named the Southland Player of the Year in addition to being a First Team All-Southland selection for both singles and doubles.
For all the latest on Islanders Tennis, like the team on Facebook (IslandersTennis), follow them on Twitter (@IslandersTennis) and visit www.GoIslanders.com.


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Tea Party Benghazi boycot leads to Fox News withdrawl
�I am having withdrawal. I do like Fox News,� said Kevin Avard, a former state lawmaker in New Hampshire who is participating in the boycott. �I have been going to CNN, and to Headline News just to get some kind of fix. I usually probably only watch them once or twice a year.�
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Rev. Harper Holding Community Meeting Today
Published: Thursday, July 18, 2013 at 9:16 a.m.
Last Modified: Thursday, July 18, 2013 at 9:16 a.m.
LAKELAND | The Rev. Alex Harper will hold a press conference and community meeting today at 5:30 p.m. in the parking lot of the First Baptist Institutional Church, 932 Martin L. King Jr. Ave. in Lakeland.
Topics will include concerns about the Voting Rights Act of 1965, the restoration of voting rights after criminal convictions and the verdict in the George Zimmerman case.
On Saturday, which has been designated a Justice for Trayvon National Day of Action, a gathering will take place at 10 a.m. in front of the Polk County Courthouse, 244 N. Broadway Ave. in Bartow.
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.


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In a move to carve a niche for itself in the burgeoning group messaging serviec market, Skype has agreed to takeover start up GroupMe.
Skype is set to face tough competition from Apple, Google and Facebook that are also going to offer group messaging service
GroupMe application allows users to make conference calls and share text with the selected users.
Skype gears up to acquire Start-Up GroupMe
The Start-Up service will compete with the Messenger service from Facebook and the 'Huddle' application of Google+.
Apple is also going to launch a new group messaging service on its smartphones soon
Skype CEO, Tony Bates wrote in his blog that this acquisition could boost their efforts to provide, "a global multi-model and multi-platform communications experience."
He appreciated the efforts of the GroupMe team that has succeeded in creating a cohesive group messaging experience which will perfectly supplement the present video, voice and text services of Skype.
Even analysts believe that it is a good time to sell GroupMe which was only one-year-old.
Insiders say the company has been sold for around $80 million and the deal is expected to be finalized soon.
Emphasizing the importance of the deal for Skype, Bates said, "We think the mobile messaging space is very important. It means furthering the breaking down of barriers to global communications."
GroupMe to operate independently
All the GroupMe's present 20 employees will join skype including the two co-founders, Jared Hecth and Steve Martocci.
Skype indicated that for now GroupMe will be operating independently and its mobile applications will continued to exist, though sometimes in near future the two companies will combined their technical knowhow to create innovative products for their users.
Meanwhile, Microsoft has announced that it will be acquiring Skype for $ 8.5 billion and the deal has been approved by the Federal Trade Commission, but the process of approval is still pending before the European Commission.
Microsoft said that it aims at integrating Skype into its Kinect, Windows Phone, Office 365 and X-Box 360.
The addition of GroupMe means closed group text messaging service will be added to the mobile apps offered in the Windows Phone 7.
GroupMe users send around 100 million messages in a month claimed the company.
The GroupMe team said in their official blog, "This has been a remarkable year for GroupMe and we believe this is a big win. And not just a big win for GroupMe and our amazing investors but also for New York city."


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On Aug. 10 at 11:36 p.m. Ontario County Sheriff's deputies responded to a domestic disturbance at the home of William Gene MacDonald, 20, of 160A S. Main St. in Naples.
While investigating, deputies allege they found MacDonald to be in the possession of marijuana. They said MacDonald, in an attempt to obstruct the investigation, allegedly grabbed a deputy by the wrist, and then fled on foot. Deputies said a taser was used to take MacDonald into custody, at which time they allegedly found him to be in possession of ecstasy, packaged for sale.
Naples Ambulance responded to examine MacDonald after a taser was used, officers said.
He was then charged with fifth-degree criminal possession of a controlled substance — a class D felony, as well as obstructing governmental administration, second-degree harassment, and unlawful possession of marijuana, they said. MacDonald will answer charges in Naples Court at a later date.
Location, ST | website.com


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640 South State StreetDover, Delaware 19901
21 West Clarke AvenueMilford, Delaware 19963
401 North Carter RoadSmyrna, DE 19977
640 S. State StreetDover DE 1990121 West Clarke AvenueMilford DE 19963
301 Jefferson AveMilford, DE 19963
1275 S. State StreetDover, Delaware 19901
Amniocentesis Animation - Amniocentesis can provide valuable information about the health of your baby before it is born. Amniocentesis is a procedure used to obtain a small sample of the amniotic fluid that surrounds the fetus during pregnancy.
Baby Due Date Tool - It is important to know your estimated due date in order to help plan for the baby's birth.
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Ovulation Date Calculator - When a person is attempting to have a baby, fertile times become an important factor. Using information about your cycles will help to predict your more fertile times and when you will ovulate.
Ovulation Date Tool - When a person is attempting to have a baby, fertile times become an important factor. Using information about your cycles will help to predict your more fertile times and when you will ovulate.
Healthy Pregnancy Guide Clinical Wizard - More than 4 million babies will be born in the United States this year alone. Now, more than ever, mothers-to-be have access to current information, advanced technologies, and skilled medical personnel. The Healthy Pregnancy Guide provides an individualized tool to help plan for a healthy pregnancy and childbirth. With medical information and practical tips, you will be well-prepared to recognize the changes that are in store for you and your baby.
Birth Defects Quiz - Here's a tough one: When is an unborn baby most at risk of developing abnormalities?
Breast-Feeding Quiz - Breast-feeding is filled with benefits to your child and you. Do you know what they are?
Contraception Quiz - About half of all pregnancies are unplanned, says the American College of Obstetricians and Gynecologists. But women today have many safe and reliable options to choose from if they want to prevent pregnancy. Test your knowledge of contraception by taking this quiz.
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Heart Quiz for Women Only - As a woman, do you know what your risk is for developing heart disease? You might be surprised. Take this quiz, based on information from the American Heart Association, and see how much you know about heart disease in women.
How To Prevent Preeclampsia Quiz - Certain women are more prone to develop a condition late in pregnancy called preeclampsia. Are you at risk? Find out what you need to know with this quick quiz.
Infant Immunization Quiz - A pregnant woman passes antibodies to her unborn baby through the placenta to protect against certain diseases. How long does this natural immunity last?
Menopause Quiz - Answer this one: A woman is considered to have begun menopause after she has missed how many menstrual cycles?
Smoking and Pregnancy Quiz - Do you know the health risks of smoking? Avoiding them can help you have a healthy pregnancy and baby.
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Common Changes During Pregnancy - Certain changes and discomforts occur during pregnancy - and are perfectly normal. Some of these changes include backache, frequent urination, and constipation. This video describes typical changes, how to safely relieve your discomfort, and what circumstances require a visit to your doctor.
Exercise During Pregnancy - There are benefits to getting regular exercise during pregnancy for most women. Work with your health care provider to develop a safe exercise program you can do throughout your pregnancy. This video discusses the benefits of exercise, as well as recommendations on how to exercise.
Hysterectomy - Hysterectomy is a major surgical procedure in which the uterus and possibly the cervix, ovaries, and fallopian tubes are removed. Fibroids in the uterus are a common reason for a hysterectomy. In this video, you'll find out other medical conditions that may require a hysterectomy and what to expect if you need this procedure.
Labor and Delivery - Labor differs from woman to woman and from pregnancy to pregnancy, but common signs and symptoms can let you know when it is starting. Contractions that increase in strength and frequency are a sure sign you are in true labor. This video discusses the three stages of labor and delivery, as well as types of delivery.
Menopause - Menopause marks the end of a woman's menstrual periods. Menopause officially begins one year after your periods have stopped completely. This video explains what occurs in the time leading up to menopause and what can be done to relieve symptoms such as hot flashes.
Ovarian Cysts - An ovarian cyst is a fluid-filled sac that forms on or in the ovary. Most cysts are harmless and don't cause any symptoms. In this video, you'll learn about different types of ovarian cysts and what treatment may be recommended if you have one.
Bayhealth is Southern Delaware's healthcare leader with hospitals in Dover and in Milford. Bayhealth provides a wide range of medical services, including cardiovascular, cancer, orthopaedics and rehabilitation, pediatrics, respiratory care, sleep care, surgical weight loss and women's services.


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Vaccine producers share many development and manufacturing problems with colleagues who commercialize other types of biopharmaceuticals. Smooth progress through R&D and clinical trials, plus cost-effective production and quick time-to-market are much sought-after. The nature and use of vaccines nevertheless presents some special issues with which producers must contend, particularly regarding scale, affordability, change-of-pace, and safety.The urgent need to increase stocks of the influenza vaccine means that producers face scale challenges that are somewhat different from those seen with other therapeutics. In the advent of a pandemic, currently existing global manufacturing capacity would only suffice to vaccinate the US population.1 This scenario has stimulated the mobilization of billions of dollars of public money and grants, and has motivated influenza vaccine-producing companies to invest in a shift in technology from eggs to cells, and to build additional manufacturing capacity.
A second issue confronting manufacturers is cost. In developing countries, the mortality rate for children as a result of infectious diseases such as pneumonia, malaria, and HIV is extremely high, but even the most basic immunizations cannot be afforded by those who need it most.
Thirdly, new vaccines for cancer or other therapeutic vaccines will open a new, highly competitive, and probably high-price market, where the leader will shape the market so that time-to-clinic and time-to-market will become a very important issue.
Finally, from a technical perspective, vaccine production is much like any other biopharmaceutical production workflow in that it generally requires about six steps: fermentation, clarification, purification, sterilization, formulation, and final filling. All of the steps need to be robust and reproducible, which is a particular challenge in biopharmaceutical manufacture because of the complexities and natural variability of biological systems. One important difference between the production of vaccines and other biopharmaceuticals, however, is the risk and safety considerations related to working with pathogens and pathogenic antigens.
The development of vaccines and manufacturing capability must therefore follow four ground rules:
In the light of these pressures, it is increasingly important to make use of the latest technologies to simplify vaccine development and manufacturing. The following sections offer insight into technology solutions that will address the needs of vaccine manufacturers.
Analytical Method Development That Drives Time-Savings
Process development should always start by defining the required target purity goals and selecting analytical methods with appropriate detection limit that are sufficiently accurate and time-efficient. As with all biomolecules purified from crude biological material, the removal of contaminants, e.g., derivatives from the host cell such as DNA, host cell protein, or leachables, must be documented. The removal or inactivation of adventitious viruses is a special challenge.
Of the in vitro and in vivo assays currently applied to vaccine production processes, some take weeks to run, although the accuracy of others, such as the single radial immunodiffusion (SRID) test used for batch-release, is limited.2


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|2009 Inductee (Football 1948/Football Coach 1959-1962)
Clarence "Sonny" Norrell was born April 24, 1926 in Corpus Christi, Texas. Norrell attended Corpus Christi High School where he was a four year letter winner in football. Upon graduation from High School he served in the United States Navy on the light cruiser, USS Miami in the Pacific. Norrell found his way back to Corpus Christi attending Del Mar College from 1946-1947 before enrolling in the University of Corpus Christi (UCC) in the Fall of 1947. While he only played during the 1948 season for the UCC Tarpons he was a trusted and well respected teammate. He graduated in the second class of UCC in January of 1950.
Norrell began a distinguished teaching career in 1950, which would span an amazing 50 years! His first teaching position was as a first grade teacher at West Oso ISD here in Corpus Christi. A couple years later he began coaching and would lead both the West Oso Football and Track and Field teams from 1952-1953. It should be noted that both Norrell and Pete Blunzer taught first grade at West Oso after serving at starting offensive tackles on the gridiron. After 4 years at West Oso, Norrell accepted a position with the London ISD on the outskirts of Corpus Christi where he taught 7th and 8th grade while coaching basketball.
In the Fall of 1956 he began working for Sundeen Independent School District and the school was at the corner of Airline and South Padre Island Drive today. He taught History and Speech and coached football. The Sundeen School District consolidated with Corpus Christi Independent School District in 1959. Norrell's teaching and coaching career came full circle in 1959 when he accepted a teaching position in the College of Education at UCC as well as a position on the football coaching staff. After four years of coaching, he elected to focus solely on his teaching career. The dedication to his profession was no more evident than the sacrifice he made to complete his Phd. From 1966 through 1968 he commuted back and forth to East Texas State University in Commerce, Texas while teaching a full load of education classes at UCC. He credits then University president, Kenneth Maroney who allowed him to teach at UCC Tuesday through Thursday and then he would drive to Commerce and work Friday through Monday until he earned his Phd. in 1968.
Norrell would officially retire in 2000 with the title professor emeritus having impacted the lives of hundreds of students over a career in education which spanned 50 years. One area that he was especially proud of was the institutions he put in place for teachers of migrant children. A close friend said, "It was a labor of love for Sonny, love for the institution and the teams. He was indeed in the business of building good character and teaching teamwork. He was one of the essential building blocks in the foundation of what is now Texas A&M University-Corpus Christi. There is no one our University could look upon with greater pride than this stalwart builder of our great alma mater." In addition to his academic accolades, Norrell is in the Miller High School Athletic Hall of Fame.
It should come as no surprise that both of his son's, Rick and Ron, followed his professional footsteps in education. Norrell and his wife Jane are enjoying their retirement years in Luling, Texas.


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Californians are counting on Gov. Jerry Brown to give final approval to a proposed new law that would end an ugly chapter in California's management of wildlife - ending the practice of "hounding" and sparing bears, bobcats and dogs the torment and abuse associated with it.
Last month, California legislature passed SB 1221 to outlaw this inhumane, unsporting and high-tech practice of using dogs to chase bears and bobcats, sending the terrified animals up trees to be shot at point-blank range, or subjecting them to long chases and attacks from the dogs who relentlessly pursue the quarry.
This straightforward bill would bring California's statutes in line with those of other states, including Colorado, Montana and Oregon, where the hunting culture long ago turned its back on such a primitive and unacceptable practice.
Adherents of hounding release as many as 20 dogs, often fitted with radio transmitters on their collars, to chase, attack and corner a panting animal with the hope of allowing the shooter a static target. There's no question that the final act of the hunt in which the hunter, following the signal emitting the hounds' collars, mocks the notion of sportsmanship or fair chase. It's more of a high-tech killing than it is a fair-chase hunt.
Spokesmen from the trophy hunting lobby claim that it's actually humane to shoot the cornered animal, since the hunter can just about guarantee a killing shot. That's the same, weak rationale for shooting any kind of animal in a fenced enclosure in a captive hunt, or any animal that is lured to bait.
But what's worse, in my mind, is the run-up to that final, pathetic act - that's the chase and every bad thing that can, and does, happen.
Hound hunters are allowed in the field with their dogs many months of the year, including much of the autumn. The fall is a critical time in the bears' annual lifecycle, where they feed constantly to build fat reserves for their long period of dormancy, or hibernation through the winter. But the houndsmen can chase the bears for hours on end, every day during the season, denying them time to feed and causing them to expend huge amounts of energy as they flee the dogs.
There are no time limits on how long a bear can be chased. Studies in professional wildlife management journals show that typical chases last for more than three hours, and sometimes go as long as 12 hours. The bears, with their large mass and heavy coats, overheat - and researchers note that this lengthy chase can even cause brain-stem damage. Bears can also become separated from their cubs during a lengthy chase that can cover miles.
After some period of being chased, the quarry will sometimes turn and fight the dogs. Just as dogfighting and cockfighting, this bloodsport deserves no state sanction. The bear may be bigger, but he or she can be overwhelmed by the sheer number of dogs turned loose and attacking him or her. And the poor bobcats can be torn to pieces by dogs.
Just about all of us, at one time or another, have felt fear when encountering an aggressive dog, even if it's just lasted for a minute. Put yourself in the position of a bear or bobcat. Imagine being chased and attacked by 20 dogs over a 12-hour period. What fear and anguish the creature must feel.
Is that not obviously and demonstrably inhumane?
Californians outlawed trophy hunting of mountain lions four decades ago, and they've affirmed that in two statewide votes, in part because packs of dogs were employed to chase and torment these noble animals. It's time to outlaw the hounding of bears and bobcats, too.
- Wayne Pacelle is the president and CEO of The Humane Society of the United States and the author of the bestselling book "The Bond: Our Kinship With Animals, Our Call to Defend Them."


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Jordan Retro X Toddler Shoes
Buy Online & Pick Up In-Store
Expecting never to see the man in the game again, the Jordan X was released with a retrospective of MJ's career. The sole of this new AJ listed some of Michael's greatest achievements from each year of his professional career. On March 19, 1995, after months of rumors, Michael ended his retirement and returned to the court.


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About the Book
In this colorful storybook with stickers, Plants vs. Zombies: The Three Little Pigs Fight Back, the famous fairy-tale pigs are thrown into the fun-dead world of Plants vs. Zombies, the award-winning video game.
Instead of the big bad wolf, the brave pigs must escape a mob of fun-loving, brain-eating zombies from the wildly popular game. The pigs will have to think fast and team up with some zombie-fighting plants to stay alive.
The fun never dies in this action-filled adventure for kids with full-color illustrations.
The three little pigs aren't afraid of the Big Bad Wolf—but zombies are another story! The pigs must use the plants in their garden to fight off the fun-dead. Will they be able to plant fast enough to save their brainy-brain-brains?
Educator and Librarian Resources
Product Details
- Imprint: HarperFestival
- On Sale: 08/06/2013
- Trimsize: 8 in (w) x 8 in (h) x 0.05 in (d)
- Pages: 24
- List Price: 4.99 USD
- Ages: 4 to 8
- BISAC1: JUVENILE FICTION / Media Tie-In
- BISAC2: JUVENILE FICTION / Horror
- BISAC3: JUVENILE FICTION / Fairy Tales & Folklore / General


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Version: 1.0 || Release Date: 2006-12-22 || License: Freeware
Developer: John Casasanta |
App Owner: johnred
3 Opinions
It is not available anymore. The download link is broken.
Does anybody know a mirror ?
Good fun in a small app. I just wish that the graphics could be moved around.


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NavyItem #37065_DTGTHS0033A
- Tottenham Forever
$44.99Goal Club Members
$41.19135Goal Club Points
Customization adds additional time to the shipping time of your order, regardless of which shipping method you choose.
Click here for Estimated Ship Date.
Represent the Spurs - the premier club of North London with this cool Tottenham Hotspur hoody. Nothing but love for the Lilywhites!
Classic sweat, ready for customization. 80/20 cotton/poly with fleece lining. Pre-shrunk. Rib collar and cuffs.
The logo on this hoody is distressed, it's meant to look weathered.
NOTE: This product was pretreated to ensure quality and long life-span of the graphic. Please wash and dry before first wearing to remove any residue that may be visible.
Lamentamos que todavia no hay descripción en español para este producto.


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EU regulation has been put in place to ensure that there are common rules around compensation for passengers who have been affected by cancellations or other flight disruption. Find out more about your entitlements and how to claim compensation, a refund or reimbursement.
British Airways, its subsidiaries and franchisees make every effort to operate to their published schedules. There are occasions however, where it is not possible to do so and a flight may be delayed or cancelled. This notification informs you of your rights under EC Regulation No 261/2004 should this happen; it does not give you any additional contractual rights. This law is applicable to all passengers departing from an airport within the EU and to all passengers travelling into an EU Member State on an EU carrier unless they have received assistance in the country of departure. It is the operating carrier's responsibility to meet these requirements. This notification also explains how to claim compensation or a refund or reimbursement under this law in respect of a flight operated by British Airways Plc or a British Airways franchisee operating BA flights in or into Europe.
If you've been on a flight departing from or flying to Israel and you've been denied boarding or your flight is cancelled, delayed or brought forward, you may be entitled to benefits under the Israel Aviation Services Law (Compensation and Assistance for Flight Cancellation or Change of Conditions), 2012.
Passengers whose flight is cancelled, shall have the choice of either:
Re-routing, under comparable transport conditions, to the final destination of the ticket presented at check-in at the earliest opportunity or at a later date at the passenger's convenience, subject to availability; or
A refund payable to the person who purchased the ticket. This applies to the part or parts of the journey not flown.
If your flight is delayed for five hours or more, the purchaser of your ticket is entitled to a refund for the part or parts of the journey not flown.
If a cancellation or delay of five hours or more disrupts a connecting journey for which you hold a through ticket (with a planned connection time of 24 hours or less) and you no longer wish to continue to your destination, the operating carrier will provide a return flight to the original point of departure at the earliest opportunity as well as refunding the parts of the journey not flown. If you choose not to continue with your journey and decide to return to your point of departure, the purchaser of your ticket is entitled to receive a reimbursement for the part(s) of the journey which were flown, providing that you can prove that the journey no longer serves any purpose in relation to your original travel plans. To obtain a reimbursement of a flown sector, the purchaser of the ticket must make the claim at the same time as claiming the refund of the unflown sectors.
If you bought your ticket from a travel agent, you must send your refund request to them. If you bought your ticket on ba.com, visit Manage My Booking for cancellation and refund options.
You will need to provide in writing your name and contact details, ticket number, booking reference, flight number, date and details of the claim you are making and supporting documents (e.g. unused ticket coupons).
Where a flight has been cancelled, or is subject to a long delay, passengers are entitled to refreshments and meals in a reasonable relation to their waiting time as well as means of contacting two people outside the airport. These provisions apply according to the duration of the expected delay and the distance of the flight as follows:
Delay of two hours or more for flights of 1500 km or less
Delay of three hours or more for all flights within the EU of more than 1500 km and all other flights between 1500km and 3500 km
Delay of four hours or more for all other flights.
In addition, the operating carrier will provide hotel accommodation if necessary and provide transport between the airport and place of accommodation. Passengers will be advised of the arrangements for obtaining refreshments, transport and hotel accommodation, by the carrier.
Compensation can be claimed where you are either:
1) Delayed at your final destination by more than three hours and that delay arises from causes within the carrier's control (rather than extraordinary circumstances which could not have been avoided by all reasonable measures).
2) Informed of a cancellation less than fourteen days before the planned departure date that arises from causes within the carrier's control (rather than extraordinary circumstances which could not have been avoided by all reasonable measures), unless you are offered a re-route which allows departure and arrival at your final destination within the following times:
If you are informed of the cancellation between thirteen and seven days before the scheduled time of departure and are offered re-routing, allowing you to depart no more than two hours before the scheduled time of departure and to reach your final destination less than four hours after the scheduled time of arrival; or
If you are informed of the cancellation less than seven days before the scheduled time of departure and are offered re-routing, allowing you to depart no more than one hour before the scheduled time of departure and to reach your final destination less than two hours after the scheduled time of arrival.
The levels of compensation are specified as follows:
EUR 250 for flights of 1500 km or less
EUR 400 for flights within the EU of more than 1500 km and for all other flights between 1500km and 3500 km
EUR 600 for all other flights.
Compensation is reduced by 50% if any re-routing offered to your final destination results in a scheduled arrival time which does not exceed the scheduled arrival time of the original flight by:
Two hours for flights of 1500 km or less
Three hours for all flights within the EU of more than 1500 km and for all other flights between 1500km and 3500 km
Four hours for all other flights.
Please note that passengers are not entitled to compensation if they have been informed of a cancellation fourteen days or more before the planned departure date. Passengers will be informed of cancellations via the contact details given to the operating carrier with the booking by the passenger, the purchaser of the ticket or the travel agent.
To make a claim for compensation (excluding flights operated by SUN-AIR, BA8200-8299) please contact British Airways Customer Relations via the online form. Please remember that the person making the claim must be one of the passengers.
Alternatively, you can write to:
British Airways Customer Relations
EU Compensation Claims
PO Box 1126
United Kingdom
To make a claim for compensation for a flight operated by SUN-AIR, you can write to:
SUN-AIR of Scandinavia A/S
Customer Relations
Cumulusvej 10
Billund DK-7190
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In addition, passengers' rights in respect of a delay only arise if they have presented themselves for check-in in good time. If you do have any complaints regarding your ability to exercise your rights, please contact our Customer Relations department.
In the event that your complaint is still not answered to your satisfaction, please contact the CAA:
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PHOTOS - Ireland's top ten free heritage sites photo gallery
In a bid to make Ireland's beautiful and historic tourist attractions accessible the Office of Public Works (OPW) has introduced free first Wednesdays of every month. This means that from July 2011 Ireland's famous heritage sites will be open to everyone.
According to the RTE report the OPW hopes that their initiative will attract more national and international visitors to the site.
Here is our list of the top ten heritage sites that everyone should go and visit -
1. Kilmainham Gaol, County Dublin
Kilmainham Gaol is now a museum but played an important part in Irish history, as many leaders of Irish rebellions were imprisoned and some executed in the prison by the British and latterly in 1923 by the Irish Free State.
In the period of time extending from its opening in 1796 until its decommissioning in 1924 it has been, barring the notable exceptions of Daniel O'Connell and Michael Collins, a site of incarceration of every significant Irish nationalist leader of both the constitutional and physical force traditions. Its history as an institution is intimately linked with the story of the Irish nationalism.
2. Kilkenny Castle, County Kilkenny
Kilkenny Castle was built in 1195 by William Marshal, 1st Earl of Pembroke. It was a symbol of Norman occupation and in its original thirteenth-century condition it would have formed an important element of the defenses.
In 1967 the property was transferred to the people of Kilkenny for £50.
PHOTOS - Ireland's top ten free heritage sites photo gallery
3. Newgrange, County Meath
Dating back to 3200 B.C the passage tomb at Newgrange is older than the pyramids in Egypt and is officially a World Heritage site.
A large mound, spread over an acre is surrounded by 97, uniquely carved curbstones. The cremated remains of the dead were buried a large stone basins under the mound in a chamber assessable by a narrow passage.
At dawn on the December 21, the shortest day of the year, every year, sunlight shines directly into the central chamber of the tomb. It is believed that this was an ancient way of measuring the passage of time, like a calendar for the ancient farmers, or that the light has some religious significance for those in the afterlife.
Newgrange is part of the Bru na Boinne complex which includes similar tombs at Knowth and Dowth.
4. Dublin Castle, State Apartments, County Dublin
The State Apartments in Dublin Castle are an extensive suite of rooms which were used by the Lord Lieutenant of Ireland for personal accommodation and public entertaining. Most of the rooms date from the era of British rule in Ireland.
Nowadays these richly decorated rooms are used by the Irish Government for official engagements including policy launches, hosting of State Visit ceremonial, and the inauguration of the President every seven years.
Top ten greatest places in Ireland to visit
Top ten places to see in Ireland
The Irish America Hall of Fame officially opens in Ireland - PHOTOS
5. Patrick Pearse Cottage, County Galway
This small restored cottage overlooking the lakes and mountains of Connemara was used by Patrick Pearse (1879-1916) leader of the 1916 Rising, as a summer residence and summer school for his pupils from St Endas, in Dublin.
The interior, although burned during the War of Independence, has been reconstructed and contains an exhibition.
6. Dunmore Cave, County Kilkenny
Dunmore Cave is a limestone cave in Ballyfoyle, County Kilkenny. The cave is particularly well known for its rich archeological discoveries and for being the site of a Viking massacre in 928. It contains almost a quarter of a mile of passages and at its deepest point is 150 foot below the surface. The beauty and magic of its calcite formations as well as its scientific and historical interest make it one of Ireland's most fascinating caves.
7. Ross Castle, County Kerry
Ross Castle is is located on the edge of Lough Leane, in Killarney National Park. It is considered a typical example of the stronghold of an Irish Chieftain during the Middle Ages. The date of its foundation is uncertain but it was probably built in the late 15th century by one of the O'Donoghue Ross chieftains.


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On www.FanFiction.net -- an online archive for those who put their own spins on existing books, TV shows, movies and comic books -- there are hundreds of thousands of "fan fiction" works. Here are the top five genres on this archive alone:
1. The Harry Potter series (627,208)
2. "Twilight" (206,126)
3. "Lord of the Rings" (47,702)
4. "Percy Jackson and the Olympians" (34,453)
5. "The Hunger Games" (28,551)
Contact Angela Hill at firstname.lastname@example.com, read her Sunday Give 'Em Hill column, or follow her on Twitter @giveemhill.


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Top Definition
Man Slip (adjective): To become unable to control sexual release.
When Matt was waiting to go into the club he saw a very attractive man and had a man slip.
viết bởi PW87 12 Tháng hai, 2009
Trending Now
Can you define these popular missing words?
whilst paul lay next to the squirrel he had a manslip
viết bởi rrdwave 19 Tháng mười một, 2009


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Gilbert, Nonnewaug roll to big victories
Tony Ortiz Jr. scored five touchdowns, four by rushing and another receiving, to lead the Gilbert-Northwestern football team to its second straight win, 48-21 over Granby, on Saturday afternoon in Winsted.
Ortiz rushed for 197 yards, had scoring runs of 3, 27, 47 and 5 yards, and also caught a 53-yard scoring pass from John Lippincott.
Seth Dayton had a 30-yard interception return for a touchdown for the Yellowjackets (2-0). Lippincott passed for 157 yards and rushed for 51 yards, including an 8-yard touchdown run.
Nonnewaug 26, Haddam-Killingworth 6: In the season opener, Nick Bordierre scored on runs of 60 and 20 yards to lead the Chiefs in a Pequot Conference game in Woodbury.
Christian Metallo scored on a 55-yard run, Trevor Scappatura added a 65-yard punt return for a score and Mark Violette added a two-point conversion run.
Troy Hardisty, Ryan Gunnoud and R.J. Burke had interceptions, and Burke chipped in with 10 tackles from his middle linebacker position.
Vinal Tech 19, Wolcott Tech 12: Asante Maldon had rushing touchdowns of 85 and 13 yards for the Wildcats in Torrington.
Vinal Tech broke a 12-12 tie with a touchdown run of seven yards wih 2:12 left in the game.
Morgan 48, Housatonic-Wamogo 8: Nick Camardi had a rushing TD and Tyler Sebben added 58 rushing yards for the Mountaineers in Falls Village. Chance Oniel had 84 yards on six kick returns for the Mountaineers (0-2).
Salisbury 47, Taft 21: Denzel Knight rushed for five touchdowns to lead Salisbury in Watertown.
Quentin Harris passed for 306 yards and two TDs for Taft (0-1), and former Naugatuck standout Mick Pernell caught three passes, including a 27-yard touchdown. Alex Huard also caught a 55-yard TD pass.
New Fairfield 46, Oxford 25: On Friday, host New Fairfield scored 26 fourth-quarter points to rally from a 25-20 deficit in an SWC game.
Kyle Chudoba passed for 299 yards and two scores, one to Chris VanKamerik (eight receptions, 89 yards) and another to Kevin Loschiavo, who caught seven passes for 159 yards.
Chudoba, Losciano and Eric Jensen had interceptions. Steve Persson ran for 125 yards for Oxford (1-1).
Brookfield 34, Pomperaug 21: On Friday, Ryan Johannes caught TD passes of 12 and 24 yards from Wade Prajer (16-of-23, 231 yards, three TDs) and Jack Yule caught a third scoring pass for the visiting Panthers (0-2).
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Concord Monitor: Just how well does Scott Brown know New Hampshire?
Brown, a talented and telegenic lawyer, will prove too moderate to win a Republican Party primary in New Hampshire – unless he attempts a dramatic Etch-A-Sketch shakeup of his positions.
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User Reviews & Ratings - Excedrin Back and Body oral
Read user comments about the side effects, benefits, and effectiveness of Excedrin Back and Body oral.
Overall User Ratings18 Total User Reviews
User Reviews
Learn about
User Reviews
Reviewer: justin, 45-54 Male on Treatment for 1 to less than 2 years (Patient)
Ease of Use
I use this when I have kidney stone back pain. It works better than my prescription pain killer that my doctor prescribed.
Reviewer: 55-64 Female on Treatment for 5 to less than 10 years (Patient)
Ease of Use
Reviewer: maria w, 25-34 Female on Treatment for 1 to less than 2 years (Patient)
Ease of Use
this is the only thing that help me with my back n head n more.....<3
Reviewer: 55-64 Female on Treatment for less than 1 month (Patient)
Ease of Use
It works for a short period of time, but during that time it does make it easy for me to get around. I think I need something stronger and lasts longer than a few hours. I take 8 a day for the last 2 weeks.
found this review helpful.
Was this review helpful? Yes | No
Reviewer: 19-24 Female on Treatment for less than 1 month (Patient)
Ease of Use
i used it to get rid of back ache didnt work for me at all took 5 pills in 3 hours did not get any relief
found this review helpful.
Was this review helpful? Yes | No
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Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately.


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Media Rage
This app is just so incredibly packed with features... It pretty much automates anything you need to do with music files.
Renaming based on tags, retagging based on file name/directory name, tag editor, artwork browser, etc...
From the creator:
"Media Rage can read and write information stored in MP3, AAC/MP4, FLAC, AIFF, WAVE, BWF, and Ogg Vorbis audio files. Media Rage can assist you in cataloging, organizing, sorting, and updating thousands of audio files with ease."
Required OS: not specified
Tags: mp3 , flac , aac , ogg , id3 , music , tagger
6 Opinions
I don't mind the interface and love the tools it has to offer. But in Leopard & Snow Leopard it has been buggy for me. The primary issue is that it always crashes when I drag a file or folder onto the dock icon and click in any of the quickedit fields. I have to navigate through the clunky interface to the quickedit tool and then drag the file or folder into the quickedit window. I just want to drag onto the icon and be done with it!
That said, I'm going to try switching to The Tagger It does everything I need it to do (extensive ID3 tag fields, artwork, file renaming, play/preview) and seems to be more frequently updated and maintained. I will miss being able to rename files into folders based on ID3 tag info, but making a new folder is not a big task.
Wow. Where has this been all my life?
very useful for some things. too complex GUI for me.
And why can't I seem to find a way to append a prefix to a tag or remove set number of characters from a tag (e.g. remove the first 3 characters of the title tag which would help me remove a track number and space found in some tracks)
it's very useful, but far from perfect; it's sad that so much work has gone into powerful tools only to hide them under an arcane interface; overall has some annoying gaps and a truly degenerate interface; many parts of the interface that could be dynamic are not; the tag text fields are fixed length and much too short; it doesn't do obviously useful things, like drag & drop text selections among text fields in the tagging panes; it doesn't warn you if you type more text than a tag field will hold (e.g. id3v1 tags) or if you try to save tag info with no tag version set (all tag data is then dumped); QuickEdit (Multiple) is missing a some features from QuickEdit (Single) for no good reason; many of the separate modules could be merged, and the modules have strange hieroglyphic icons
great app. I love it. It's just perfect.
I wanted to like this aplication "A LOT" - but I can't. It does do a lot and looks very powerful. But I just can't get over the small things that bother me about the interface. I like my MP3 taggers in one main window, sort of like iTunes main window. And this seems to me like a collection of many disjointed tools that get launched from a launch pad window.
Some tools are very nice, but even there they are missing little touches. For instance, the art finder only has a few Amazon sites (it missed Canada and France) plus there are a number of other sites for covers that contain much better scans with higher resolutions. The main issue is that the "Search" allows you only to type ONE data field. You can pick bwteen Album name or Artist name but you cannot pick BOTH to search on. So you may end up with a results list that is 100 or more lines long - and now you will have to look at those manually to pick the one you want.
The best taggers that have ever been written (in my opinion) are Tag&Rename along with Dr. Tag. Unfortunately they're both Windows-only. :(


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Quote: I do not know what comes next.Nor do I know what just happened. All I know is that the only relief from this pain is the presence of gratitude. Gratitude that I was able to spend so many beautiful years with Ms. Zeem. Gratitude for my loving friends and family. Gratitude for all the love and abundance in my life. A gratitude that I wish had come sooner, but thank with all my heart that it has finally seen the light of day
wrote: why do you hate me now?
those were four great years.
i hate you!


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Judge Rules for Wynn Amid FCPA Spat
Wynn Resorts Ltd. won a legal test of its move early this year to oust major shareholder Kazuo Okada and former business partner of Chief Executive Steve Wynn, amid dueling accusations between the two over potential violations of a U.S. foreign bribery law.
A Nevada state judge denied a request by Okada to reinstate his shares in Wynn's casino empire ahead of the company's annual meeting next month, The Wall Street Journal reported.
Judge Elizabeth Gonzalez ruled Tuesday that Okada didn't present enough evidence to indicate he would prevail in further legal proceedings. As such, she denied his request for a preliminary injunction overturning the redemption of his 19.6% holding in Wynn, which the company ordered in February.
Attorneys for Okada argued that the court here should issue a preliminary injunction that would reinstate his shares and allow him to participate in board nominations and votes related to the company's annual meeting. Okada, who remains a Wynn director, didn't attend the hearing.
Tuesday's decision denied Okada the "rights to nominate and vote for independent directors willing to stand up to Steve Wynn and promote good corporate governance that puts the interests of shareholders first," said Okada's company, Aruze USA Inc. Aruze said it looked forward to a jury trial on the merits of its case.
Wynn lawyer Robert Shapiro said the company expected to continue to prevail in its protracted legal battles with Okada.
The judge ruled that Okada could obtain some documents he requested from the company as a Wynn director. Okada since January has been in court pursuing the documents, which relate to Wynn's investments in the Chinese gambling enclave of Macau.
Okada alleged that the company may have acted improperly by donating funds to a university foundation in Macau, in potential violation of the U.S. Foreign Corrupt Practices Act. The law bars improper payments to foreign officials for a business advantage.
Wynn denied any impropriety.
Wynn forcibly redeemed Mr. Okada's ownership stake after an investigation conducted for the company concluded that he had engaged in improper practices while developing a casino in the Philippines that violated the FCPA.
Click here to read the full story.


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Yarn Profile: Classic Elite Newport Cotton
First Impressions
Knitting Up
I switched to a pair of dull-tipped Addi Turbo circulars and the snagging subsided somewhat, but I had to be careful.
Snagging aside, stitches appeared even and consistent. The clear stitch definition in this yarn makes it ideal for complicated stitch work.
Blocking / Washing
Stitches tended to lean against one another in uneven waves, and edges didn't want to straighten. The yarn softened and expanded only slightly, and there was no bleeding, fading, or stretching.
After a moderate amount of wear, however, the swatches began to pill. Extensive rubbing caused the stitches themselves to blur and lose their surface definition.
I can imagine that a heavily worn sweater in this yarn would carry you through just one season before showing its age.
If you can get the snagging under control, the yarn knits up at a breezy pace of 4 stitches per inch. Combine that with Classic Elite's gorgeous color selection, and you've got yourself a good warm-weather yarn.Add your comments
Reader Comments
"Why would you knit with a yarn when the samples do not wash well? I think that my choice for cotton for knotting is the Brown Sheep Cotton/wool blend. This is soft, washes well, and lasts -- also their color selection is great!! As this is only 20% wool it's enough to overcome the natural problems of cotton, but not enough to allow the knitter to reap the benefits." Barbara F., 3/10/01
"For a more durable cotton by Classic Elite, I prefer Provence. It is not as soft, but crisp, has beautiful stitch definition, and doesn't pill. It comes in 100g skeins for $11.50. For the extra $.50, I'd go for Provence." Laura T., 3/08/01
"I agree with you 100% on the Newport Cotton. I made a summer sweater in a brocade pattern from their book and the sweater started to pill after the second washing. I would never knit with this cotton again and it's a shame since the outcome is so nice." Ana, 3/08/01
Yarn name
Newport Cotton
Classic Elite Yarns
Fiber content
100% mercerized Pima cotton
4 sts / inch using 5.5mm (US 9) needles
Average retail price
Where to Buy Online
Got Yarn
Weight/Yardage per Skein
50g / 70 yards
Country of Origin
Manufacturer's suggested wash method
Hand wash cold, dry flat.
Review date


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- Home
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A Conversation with Henry Bloch
Thursday, June 11, 2009
8:30pm @ Central Library
To mark the grand opening of the H&R Block Business and Career Center at the Central Library, join us for a public conversation with Henry W. Bloch, co-founder and chairman emeritus of H&R Block. Conducted by Crosby Kemper III, director of the Kansas City Public Library, the program takes place on Thursday, June 11, at the Central Library at 6:30 p.m.
Bloch will discuss how the entrepreneurial start-up he and his brother Richard founded in Kansas City in 1955 grew to become the world's largest tax services company, a publicly-traded corporation that in 2008 served 23.5 million clients at more than 13,000 U.S. retail offices and through its digital tax solutions.
During the course of the conversation, Bloch will touch on many of the highs (and lows) of his storied career as one of Kansas City's most successful entrepreneurs. Among these include the early struggling days of his predecessor firm in the late 1940s called United Business Company that offered bookkeeping and other services to small businesses; the unanticipated effect of an advertisement in The Kansas City Star in January 1955 that uncovered the overwhelming need for tax preparation services; the decision to rename the company H&R Block; the unlikely birth of the H&R Block franchise network in New York; Henry Bloch's role as a consummate television spokesman that made the company one of the most recognized brands in American business; and how the company faced the challenges brought on by the diagnosis that brother Richard Bloch had terminal lung cancer.
Henry Bloch was born July 30, 1922, the second son of a prominent Kansas City lawyer. He attended Southwest High School, began his college career at the University of Kansas City, and later transferred to the University of Michigan, from which he graduated in 1944. During World War II, Bloch served in the U.S. Eighth Air Force as a navigator on B-17 bombers and flew 31 combat missions over Germany. He was awarded the Air Medal and three Oak Leaf Clusters.
Today, Henry Bloch is widely known as a businessman, civic leader, and supporter of the arts and education who works to improve the quality of life in Kansas City. A generous gift to the Nelson-Atkins Museum of Art from Henry and Marion Bloch created the Bloch Building, which houses the museum's contemporary and African art as well as photography and special exhibits, and increased the museum's capacity by 55 percent. His generosity also created the Henry W. Bloch School of Business and Public Administration at the University of Missouri-Kansas City.
The H&R Block Business and Career Center at the Central Library is made possible through the generous support of H&R Block and the H&R Block Foundation.
Admission to A Conversation with Henry Bloch is free. A 6 p.m. reception precedes the event. Click here or call 816.701.3407 to RSVP. Free parking is available in the Library District Parking Garage located at 10th and Baltimore.


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This Emotional Life – Tune In!
This is a guest blog post from our friends at Vulcan Productions and NOVA/WGBH…
On the eve of a new year, as millions of Americans search for more meaning in their lives, Vulcan Productions and NOVA/WGBH have teamed with Harvard psychologist and best-selling author of Stumbling on Happiness, Professor Daniel Gilbert, to produce This Emotional Life.
This Emotional Life is a two-year outreach campaign anchored by a three-part, national broadcast series on PBS (airing Jan. 4-6, 2010) that examines the science behind our emotions, the challenges to our well-being and the keys to leading happier lives. We are so excited to engage the Autism Speaks community in our campaign. Everyone who lives with autism understands what an emotional journey it can be. This campaign aims to provide individuals with resources to make that journey a little easier.
Spearheaded by Microsoft co-founder Paul Allen's Vulcan Productions, the project includes the PBS series – which features compelling personal stories and cutting edge research, along with revealing insights from celebrities including Larry David, Alanis Morissette, Robert Kennedy Jr., Chevy Chase and Richard Gere – a dynamic and content-rich website, a national outreach campaign and educational toolkits created to support topics within the series.
The first show focuses on relationships – how they're built and why they're important to human happiness. One of the stories in this first show is about Jason, a 29-year old man with Asperger's syndrome. Jason discusses his constant struggle reading others' emotions and signals, making it difficult for him to form relationships. He shares his daily struggle to be successful in social situations, a common issue for people with autism spectrum disorders. His story offers viewers a glimpse into the difficulties and frustrations those living with autism often face in their everyday interactions. You can take a look at some of Jason's story here:Vodpod videos no longer available.
The campaign will continue on for two years post-broadcast. Through our website, the distribution of our early childhood attachment and military family toolkits, and several other initiatives, we will continue to promote the mission of this project. We are partnering with great organizations such as the National Alliance on Mental Illness, the Depression and Bipolar Support Alliance, Mental Health America, the Mayo Clinic and the Substance Abuse & Mental Health Services Administration.
You can view the trailer and learn more about the program on the "This Emotional Life" web site.
It is our hope that this campaign will offer you and your families support – whether it is through relating to stories like Jason's, or visiting our website and finding information, resources in your area, or support from people just like you.
For more information, go to www.pbs.org/thisemotionallife.


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via Personal Recipe 1716945:
hahahahaha who ever was in there I hope you tipped it over. ;)
I want a miniature of that sanitary! And if you look inside, I'd like to see written in the WC "Dookie".
dude, tht is cool. where was that.
OMG!!! Cool..! :D
AHAHAH!!! OMG have you tried to call this number??? XD
Hahahahahaha my god xD ok i know i'm crazy but.. someone has to decide this and it was me xD now i decided that December 11th it will be Green Day's international day!!! Just in honour of the coming out of your 11th album!!! Now you can call me a real green day fan xD
True story.


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Saints hire new running backs coach
Published: Saturday, February 16, 2013 at 6:01 a.m.
Last Modified: Sunday, February 17, 2013 at 12:10 a.m.
METAIRIE — The New Orleans Saints have hired Michigan State offensive coordinator Dan Roushar to coach running backs and reassigned Bret Ingalls to overseeing the offensive line.
In a move announced by the team on Saturday, Ingalls takes over an offensive line that had worked since 2008 under Aaron Kromer, who left after the 2012 season to become Chicago's offensive coordinator.
Ingalls has coached the offensive line at several college stops, including his most recent at Northwestern from 2006-08 before joining New Orleans.
Roushar, who spent six seasons at Michigan State, says in a statement released by the school that moving to the Saints is an opportunity he can't pass up, but he also thinks Michigan State is poised to have a "tremendous" 2013 season.
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.


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EU Pioneer honoured
02.07.2012 - Dr. Christian Patermann, the mastermind behind the EU's bioeconomy strategy, has been honoured by the Accademia dei Georgofili in Florence. In a ceremony in the Uffizi at the end of April, Patermann was appointed as a member of the the first public association in Europe dedicated to agrarian studies.
As Programme Director Biotechnology, Agriculture and Food at DG Research of the European Commission, Patermann drafted the EU's knowledge-based bioeconomy plans.http://www.european-biotechnology-news.com/people/bio-people/2012-2/christian-patermann.html


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About the Book
"Gayle Callen is wonderful!"
—Cathy Maxwell
USA Today bestseller Gayle Callen is not only a longtime favorite among avid readers of historical romance the world over, she's a multiple award-winner as well, having won both the Holt Medallion and the Laurel Wreath Award. With Return of the Viscount, she kicks off a wonderfully sexy series set in Victorian England, where the destinies of three battle-scarred soldiers lead them to the women fated to capture their hearts and heal them. Return of the Viscount once again showcases what Romantic Times calls Callen's "forte," her ability to "entangle readers in a tale that's delightfully sexy, fast paced, and filled with engaging characters who hold your interest until the end." Return of the Viscount is an unforgettable marriage of convenience tale that will enthrall fans of Samantha James and Loretta Chase—the story of a breathtaking love affair between a soldier with a debt to pay and a lady on a quest to unravel her family's secrets.
Her marriage of convenience seems far too convenient . . .
Desperation drove Cecilia Mallory to seek a union with a stranger—one who would wed her sight unseen and grant her full access to her inheritance with no expectations whatsoever. She anticipated, perhaps, an older, undesirable, equally desperate husband—never the young, vibrant, and devastatingly attractive man who answered her call. What could such a man really be after?
Unknown to Cecilia, Viscount Michael Blackthorne, a soldier and gentleman, owes a debt of honor to Lady Cecilia's father, and granting her unusual request to wed seemed a worthy way to repay it. But an unseen threat perilously close at hand is convincing Michael thathis true responsibility is to protect the beautiful, warm-hearted lady he has married . . . the woman he is unexpectedly coming to love.
Educator and Librarian Resources
Product Details
- Imprint: Avon
- On Sale: 07/31/2012
- Trimsize: 4.188 in (w) x 6.75 in (h) x 0.96 in (d)
- Pages: 384
- List Price: 7.99 USD
- BISAC1: FICTION / Romance / Historical / General


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The Bishop O'Dowd girls volleyball team pulled out an incredibly competitive first game, taking some of the wind out of Albany's sails, and went on to post a 30-28, 25-21, 26-24 victory over the Cougars in a North Coast Section Division III semifinal on Wednesday.
"I think we did what we needed to do," Bishop O'Dowd coach Chad Salcido said. "We transitioned with consistency, and we were good passing the ball and with serve-receive, which helped us get into our fast offense."
No. 3 Albany (34-6), the defending NCS and Northern California Division III champions, battled back after trailing the entire first game to take leads of 25-24 and 27-26. But No. 2 Bishop O'Dowd righted the ship and took control.
Behind 18 kills from Brianna Karsseboom, who came up with big side-out after side-out, the Dragons (29-6) controlled game two and wiped away a 15-11 deficit in game three.
Kyra Holt had 19 kills for the Cougars.
Bishop O'Dowd will face No. 1 Campolindo, which beat Novato in the other semifinal, in Saturday's section championship. Bishop O'Dowd and Campolindo split its two meetings earlier this season.


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- Oct 8:
- California health insurance exchange reports nearly 1 million visitors in first week; 16,311 households sign up
- Insurance industry says health care website is fixable
- Oct 5:
- South Bay residents get answers to Obamacare questions
- Obamacare's winners and losers in Bay Area
- Oct 4:
- Why do Obamacare costs vary across the country?
- Oct 2:
- 3 measures of health exchanges may take years to assess
- 5 key arguments in the shutdown fight
- Sep 30:
- Young adults have 3 health care options to consider
- Sep 30:
- Obamacare and insurance exchange: 10 essential things to know
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OAKLAND -- With about 55,000 of its low-income residents newly eligible for free public health coverage, Alameda County is looking to hire 185 workers to help get them enrolled.
The county government has set up a call center in downtown Oakland to answer questions by phone about the health coverage changes coming Jan. 1 because of the federal Affordable Care Act, also known as Obamacare.
California is setting up its own health coverage exchange while also expanding the Medi-Cal safety net, allowing most children and adults under 65 to get subsidized coverage if their incomes are at or below 138 percent of the federal poverty level.
"It's a good thing," said Alameda County Social Services Agency Director Lori Cox, since many of those residents are presently uninsured and end up resorting to expensive emergency room services when they are sick.
The Alameda County Board of Supervisors voted Tuesday to approve $8.3 million in funding for about 185 full-time positions in Cox's agency. The amount will be "completely offset" by federal revenues, according to a letter to the supervisors from Cox.
The county has just 25 people operating the call center now, and officials said they received about 580 calls in the first week since the enrollment period began on Oct. 1. Each county is required to have a call center under the new law, but how many people they have answering phones will vary.
Most of the county's new hires will be "eligibility technicians" helping residents find out if they qualify for free health care, as well as food stamps and welfare-to-work benefits.
Covered California, the state's new health exchange, also operates three call centers, one of them in Concord, taking calls mostly from consumers who can afford to buy an insurance plan. But many of the poorest patients who qualify for Medi-Cal, the state's name for the federal Medicaid program, will be forwarded to the county call centers instead.
More than 221,000 Alameda County residents are already covered by Medi-Cal, but the expansion could bring another 55,000 into its safety net.
Public hospital oversight
Also with Obamacare changes in mind, the Alameda County Medical Center changed its name earlier this year to the Alameda Health System and has been expanding its public hospital consortium to better compete with private hospitals for consumers who will have more choices on the state health insurance exchange.
The network that includes Highland Hospital in Oakland and Fairmont Hospital in San Leandro is preparing to add Alameda and other San Leandro hospitals into its fold.
But several supervisors said Tuesday they wanted more say in how the semiautonomous public hospital authority is governed. The supervisors appoint most of the members of the health system's board of trustees, but the health system's board wants all new appointees to come from a pool of people of their own choosing.
"I would be very uncomfortable with relinquishing any of our authority in making appointments," said Supervisor Nate Miley, describing the appointees as the only way of keeping an eye on the public hospital system.
Added Supervisor Richard Valle: "I am very concerned about the accountability."


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Home > Patients & Visitors > Health Library > Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor Treatment (PDQ®): Treatment - Health Professional Information [NCI]
This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.
Dramatic improvements in survival have been achieved for children and adolescents with cancer. Between 1975 and 2010, childhood cancer mortality decreased by more than 50%.[1] Childhood and adolescent cancer survivors require close follow-up because cancer therapy side effects may persist or develop months or years after treatment. (Refer to the PDQ summary on Late Effects of Treatment for Childhood Cancer for specific information about the incidence, type, and monitoring of late effects in childhood and adolescent cancer survivors.)
Primary brain tumors are a diverse group of diseases that together constitute the most common solid tumor of childhood. The PDQ childhood brain tumor treatment summaries are primarily organized according to the World Health Organization classification of nervous system tumors.[2,3] Brain tumors are classified according to histology, but immunohistochemical analysis, cytogenetic and molecular genetic findings, and measures of mitotic activity are increasingly used in tumor diagnosis and classification. Tumor location and extent of spread are important factors that affect treatment and prognosis. For a full description of the classification of nervous system tumors and a link to the corresponding treatment summary for each type of brain tumor, refer to the PDQ summary on Childhood Brain and Spinal Cord Tumors Treatment Overview.
Central nervous system (CNS) atypical teratoid/rhabdoid tumor (AT/RT) is a rare, clinically aggressive tumor that most often affects children aged 3 years and younger but can occur in older children and adults. About one-half of AT/RTs arise in the posterior fossa. The diagnostic evaluation includes magnetic resonance imaging (MRI) of the neuraxis and lumbar cerebrospinal fluid examination. AT/RT has been linked to somatic and germline mutations of SMARCB1, a tumor suppressor gene. There is no current standard treatment for children with AT/RT. Multimodal treatment consisting of surgery, chemotherapy, and radiation therapy is under evaluation.
Based on present biologic understanding, AT/RT is part of a larger family of rhabdoid tumors. In this summary, the term AT/RT refers to CNS tumors only and the term rhabdoid tumor reflects the possibility of both CNS and non-CNS tumors. Unless specifically noted in the text, this summary is referring to CNS AT/RT.
The exact incidence of childhood CNS AT/RT is difficult to determine because the tumor has been widely recognized for only the last decade.
The incidence in older patients is unknown. However, in the Central Nervous System Atypical Teratoid/Rhabdoid Tumor Registry (AT/RT Registry), 12 (29%) of the 42 patients were older than 36 months at the time of diagnosis.[7]
Anatomy of the inside of the brain, showing the pineal and pituitary glands, optic nerve, ventricles (with cerebrospinal fluid shown in blue), and other parts of the brain. The tentorium separates the cerebrum from the cerebellum. The infratentorium (posterior fossa) is the region below the tentorium that contains the brain stem, cerebellum, and fourth ventricle. The supratentorium is the region above the tentorium and denotes the region that contains the cerebrum.
Clinical Presentation
Childhood AT/RT is a clinically aggressive tumor that primarily occurs in children younger than 3 years, but it also can occur in older children and has been reported in adults.[8,9]
In about one-half of patients, the tumor is located in the posterior fossa, although it can occur anywhere in the CNS.[4] Tumors of the posterior fossa may occur in the cerebellopontine angle or more midline. Involvement of individual cranial nerves has also been noted.
Because AT/RT grows rapidly, patients typically have a fairly short history of progressive symptoms, measured in days to weeks. Signs and symptoms are dependent on tumor location. Young patients with posterior fossa tumors usually present with symptoms related to hydrocephalus, including the following:
They may also develop ataxia or regression of motor skills.
Data from the AT/RT Registry suggest that approximately 20% of patients present with disseminated disease.[7] Dissemination is typically through leptomeningeal pathways seeding the spine and other areas of the brain. There are also reports of rare patients with synchronous renal rhabdoid tumor and CNS AT/RT.[10]
Diagnostic Evaluation
All patients with suspected childhood AT/RT should have MRI of the brain and spine. Unless medically contraindicated, patients should also have lumbar cerebrospinal fluid inspected for evidence of tumor. Patients may also undergo renal ultrasound to detect synchronous tumors.
AT/RT cannot be reliably distinguished from other malignant brain tumors based on clinical history or radiographic evaluation. Surgery is necessary to obtain tissue and confirm the diagnosis of AT/RT. Immunostaining for loss of SMARCB1 (INI1, hSNF5) protein expression is used to confirm the diagnosis, especially in children younger than 3 years.[11]
Prognostic factors that affect survival for AT/RTs are not fully delineated.
Known factors associated with a poor outcome include the following:
Most published information on outcomes for patients with AT/RT is based on small series and is retrospective in nature. Initial retrospective studies reported an average survival from diagnosis of only about 12 months.[4,8,14,15,16] In a retrospective report, 2-year overall survival was better for patients who underwent a gross-total resection than for those who had a subtotal resection. However, in this study the effect of radiation therapy on survival was less clear.[14]
There are reports of long-term survivors.[17] Notably, improved survival has been reported for those receiving intensive multimodal therapy.
Childhood central nervous system (CNS) atypical teratoid/rhabdoid tumor (AT/RT) was first described as a discrete clinical entity in 1987 [1] based on its distinctive pathologic and genetic characteristics. Before then, it was most often classified as a medulloblastoma, primitive neuroectodermal tumor, or choroid plexus carcinoma. The World Health Organization began classifying AT/RT as an embryonal grade IV neoplasm in 1993.[2]
Histologically, classic AT/RT is morphologically heterogeneous, typically containing sheets of large epithelioid cells with abundant eosinophilic cytoplasm and scattered rhabdoid cells, most often with accompanying components of primitive neuroectodermal cells (small round blue cells), mesenchymal cells, and/or glial cells.[3]
Immunohistochemical staining for epithelial markers (cytokeratin or epithelial membrane antigen), glial fibrillary acidic protein, synaptophysin (or neurofilament), and smooth muscle (desmin) may help to identify the heterogeneity of differentiation, but will vary depending on the cellular composition.[4] Rhabdoid cells, while not present in all AT/RTs, will express vimentin, epithelial membrane antigen, and smooth muscle actin.
Immunohistochemistry for the SMARCB1 protein is useful in establishing the diagnosis of AT/RT. A loss of SMARCB1 staining is noted in neoplastic cells, but staining is retained in non-neoplastic cells (e.g., vascular endothelial cells).[5,6,7]
AT/RT is a rapidly growing tumor that can have an MIB-1 labeling index of 50% to 100%.[2]
AT/RT is the first primary pediatric brain tumor for which a candidate tumor suppressor gene, SMARCB1 (also known as INI1 and hSNF5), has been identified.[8]SMARCB1 loss causes aberrant activation of the sonic hedgehog pathway and may drive tumorigenesis through the expression of GLI1.[9] In one series of six infants, AT/RTs were thought to arise from the superior medullary velum. Sonic hedgehog signaling through expression of GLI1 is critically involved in morphogenesis of the cerebellar midline structures, suggesting, in part, why tumors arise in this region.[10]SMARCB1 has been found to be abnormal in the majority of rhabdoid tumors, including CNS, renal, and extrarenal rhabdoid malignancies.[8] Alterations (mutations as well as gains/losses) in other genes are very uncommon in patients with SMARCB1-associated AT/RT.[11,12,13]
SMARCB1 is a component of a Switch (SWI) and Sucrose non-fermenting (SNF) adenosine triphosphate–dependent chromatin-remodeling complex.[14] The exact function of the SMARCB1 gene is unknown, but it is likely that a mutation results in altered transcriptional regulation of downstream targets. Rare familial cases of rhabdoid tumors expressing SMARCB1 and lacking SMARCB1 mutations have also been associated with germline mutations of SMARCA4/BRG1, another member of the SWI/SNF chromatin-remodeling complex.[7,15]
In addition to somatic mutations, germline mutations in SMARCB1 have been reported in a substantial subset of AT/RT patients.[8,16] A study of 65 children with rhabdoid tumors found that 23 (35%) had germline mutations and/or deletions of SMARCB1.[5] Children with germline alterations in SMARCB1 presented at an earlier age than sporadic cases (median age, approximately 5 months versus 18 months) and were more likely to present with multiple tumors.[5] One parent was found to be a carrier of the SMARCB1 germline abnormality in 7 of 22 evaluated cases showing germline alterations, with four of the carrier parents being unaffected by SMARCB1-associated cancers.[5] This indicates that AT/RT shows an autosomal dominant inheritance pattern with incomplete penetrance.
Gonadal mosaicism has also been observed, as evidenced by families in which multiple siblings are affected by AT/RT and have identical SMARCB1 alterations, but both parents lack a SMARCB1 mutation/deletion.[5,6] Screening children diagnosed with AT/RT for germline SMARCB1 mutations may provide useful information for counseling families on the genetic implications of their child's AT/RT diagnosis.[5]
Rhabdoid Tumor Predisposition Syndrome (RTPS)
RTPS, related primarily to germline SMARCB1 alterations, has been clearly defined.[8,16] RTPS is highly suggested in patients with synchronous occurrence of renal malignant rhabdoid tumor and AT/RT, bilateral malignant rhabdoid tumors of the kidney, or malignant rhabdoid tumors in two or more siblings.
This syndrome is manifested by a marked predisposition to the development of malignant rhabdoid tumors in infancy and early childhood. Up to one-third of AT/RTs are thought to arise in the setting of RTPS, and the majority of these occur within the first year of life. The most common non-CNS malignancy of RTPS is the malignant rhabdoid tumor of the kidney, which is also noted in infancy.
For more information about RTPS, refer to the Rhabdoid predisposition syndrome section in the PDQ summary on Wilms Tumor and Other Childhood Kidney Tumors Treatment.
There is no defined staging system for childhood central nervous system atypical teratoid/rhabdoid tumor. For treatment purposes, patients are classified as having newly diagnosed or recurrent disease with or without neuraxis dissemination.
There is no established standard treatment for children with central nervous system (CNS) atypical teratoid/rhabdoid tumor (AT/RT). Given the highly aggressive nature of the tumor, most patients have been treated with intensive multimodal therapy. However, the young age of most patients limits the extent of treatment, particularly radiation therapy.
Treatment options for newly diagnosed CNS AT/RT include the following:
Surgery, Chemotherapy, and Radiation Therapy (Multimodal Therapy)
The extent of the surgical resection may affect survival. Data from the Central Nervous System Atypical Teratoid/Rhabdoid Tumor Registry (AT/RT Registry) suggest that patients who have had a complete resection may have a longer median survival, although complete surgical resection is often difficult given the invasive nature of the tumor.[1]
Chemotherapy has been the main adjuvant therapy for very young children with AT/RT. Cooperative group studies that included children younger than 36 months demonstrated poor survival when treated with standard chemotherapeutic regimens alone.[2] The Children's Cancer Group reported a 2-year event-free survival (EFS) of 14% for 28 children younger than 36 months treated with multiagent chemotherapy.[3]
Intensive regimens that utilize varying combinations of high-dose chemotherapy,[4][Level of evidence: 3iA]; [5,6][Level of evidence: 3iiiDi] intrathecal chemotherapy, and radiation therapy have led to prolonged survival for some patients. Thirteen patients in the AT/RT Registry were treated with high-dose chemotherapy with hematopoietic stem cell rescue as part of initial therapy.[1] Four of these patients, two of whom also received radiation, were alive without progressive disease 21.5 to 90 months following diagnosis at last report. Of 15 evaluable children, all younger than 32 months at diagnosis, who were on a chemotherapy Head Start III protocol, 2 survived for more than 47 months.[7][Level of evidence: 3iA]
Radiation therapy appears to have a positive impact on survival for AT/RT patients.
Evidence (multimodal therapy):
Because AT/RT is responsive to radiation therapy, this modality is incorporated into many treatment protocols.[13]
Prospective cooperative group clinical trials for AT/RT are greatly needed to better understand how age and extent of therapy affect survival.
Treatment Options Under Clinical Evaluation
Early-phase therapeutic trials may be available for selected patients. These trials may be available via Children's Oncology Group phase I institutions, the Pediatric Brain Tumor Consortium, or other entities. Information about ongoing clinical trials is available from the NCI Web site.
There is no standard treatment for recurrent childhood central nervous system atypical teratoid/rhabdoid tumor.
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with childhood atypical teratoid/rhabdoid tumor. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.
General information about clinical trials is also available from the NCI Web site.
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.
This summary was reformatted.
This summary was comprehensively reviewed.
This summary is written and maintained by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.
Purpose of This Summary
This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the treatment of childhood central nervous system atypical teratoid and rhabdoid tumor. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions.
Reviewers and Updates
This summary is reviewed regularly and updated as necessary by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of the National Cancer Institute (NCI). The summary reflects an independent review of the literature and does not represent a policy statement of NCI or the National Institutes of Health (NIH).
Board members review recently published articles each month to determine whether an article should:
Changes to the summaries are made through a consensus process in which Board members evaluate the strength of the evidence in the published articles and determine how the article should be included in the summary.
The lead reviewers for Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor Treatment are:
Any comments or questions about the summary content should be submitted to Cancer.gov through the Web site's Contact Form. Do not contact the individual Board Members with questions or comments about the summaries. Board members will not respond to individual inquiries.
Levels of Evidence
Some of the reference citations in this summary are accompanied by a level-of-evidence designation. These designations are intended to help readers assess the strength of the evidence supporting the use of specific interventions or approaches. The PDQ Pediatric Treatment Editorial Board uses a formal evidence ranking system in developing its level-of-evidence designations.
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National Cancer Institute: PDQ® Childhood Central Nervous System Atypical Teratoid/Rhabdoid Tumor Treatment. Bethesda, MD: National Cancer Institute. Date last modified <MM/DD/YYYY>. Available at: http://www.cancer.gov/types/brain/hp/child-cns-atrt-treatment-pdq. Accessed <MM/DD/YYYY>.
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Last Revised: 2014-09-05
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Adventure race set for Thibodaux
Published: Tuesday, December 4, 2012 at 4:35 p.m.
Last Modified: Tuesday, December 4, 2012 at 4:35 p.m.
The Sports Medicine Center of Thibodaux Regional Medical Center is hosting an adventure race at 8 a.m. Saturday.
The adventure race will consist of 10-15 miles of biking, 4-7 miles of trekking or running and many other exciting and unique mystery challenges. The race is designed to take participants through the scenic and historic surroundings of Thibodaux.
The race will accept two-man teams in four divisions in coed, all-male, all-female and masters (average age 55 or older). Teams must consist of at least one adult. The team captain must be 18 years or older, and all racers must be at least 15 years old on race day.
For more information on registration, contact race director Clay Dennig at firstname.lastname@example.com.
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.


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All waiting lists for public housing in Meridian are now closed.
Meridian Housing Authority officials say the demand for public housing in Meridian is staggering.
'We're not taking applications for any bedroom size right now. It closed on April 4th. We had so many applicants that we just had to close the waiting lists.'
Jill Walker is the Tenant Selection and Section 8 Manager for the Meridian Housing Authority. She estimates that there are currently more than 1100 people on waiting lists.
According to Walker, the MHA developments that were recently renovated, such as Carousel Place and Frank Berry Courts, are not the developments with lists that her office has closed. Instead, the waiting lists she's referring to are for MHA's other developments. Those waiting lists were closed in April.
'Our policy states that we try not to have more people than we can serve within a 12-month, or one year period,' says Walker.
The twelve developments that the Meridian Housing Authority owns consist of more than 1200 apartments. Of those, there are currently only 13 vacancies.
'When they apply we tell them it could take six months to a year. There is a need. There's a desperate need for housing,' says Walker.
Last year officials with the Meridian Housing Authority say there was about a 25% increase in demand for public housing within the city.
As for the waiting lists that have closed, next week three of those lists will reopen. The lists for the three, four and five bedroom units will reopen Wednesday, June 27th for people who qualify. Currently, there's no word on when waiting lists for the one and two bedroom apartments will reopen.


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President Franklin D. Roosevelt signs the Migratory Bird Hunting and Conservation Stamp Act into law.
First duck stamp, designed by Pulitzer-prize winning editorial cartoonist, Jay N. "Ding" Darling, issued.
Prairie drought peaks.