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Oracle OpenWorld 2013 hands on labs: HOL9981, HOL9982 and HOL10003
By Simon Coter-Oracle on Sep 16, 2013
Oracle OpenWorld 2013 will start in a few days. As every year, among the 2000+ sessions presented there will be many Hands on labs.
These labs are a unique opportunity to better understand several Oracle products (applications, database, middleware, OS, virtualization, ...). The idea of these labs is to enable 40 to 50 customers and partners to meet in a room and install/configure/use Oracle products on laptops during 1 or 2 hours, following detailed documentation and being helped by several Oracle experts.
Once again, thanks to Doan Nguyen (Principal product marketing director for Oracle VM), Olivier Canonge, Christophe Pauliat and I will run labs about Oracle VM for X86 virtualization.
This year, we were able to propose 3 labs. See details below.
HOL10003: Deploy and Manage a Private Cloud with Oracle VM and Oracle Enterprise Manager 12c
|Date: Monday September 23, 3:15pm - 4:15pm
Location: Mariott Marquis Hotel, Room Nob Hill CD
Detailed documentation (PDF)
HOL9981: Best Practices for Migrating to Oracle VM and Oracle Linux from VMware and Red Hat
|Date: Monday September 23, 1:45pm - 2:45pm
Location: Mariott Marquis Hotel, Room Nob Hill CD
Detailed documentation (PDF)
HOL9982: Oracle Real Application Clusters 12c: Deploying Four Nodes in Minutes with Oracle VM Templates
|Date: Tuesday September 24, 5:15pm - 6:15pm
Location: Mariott Marquis Hotel, Room Nob Hill CD
Detailed documentation (PDF)
If you attend Oracle OpenWorld and are interested by Infrastructure Cloud or Virtualization, add those labs to your calendar using the Schedule Builder tool.
If you cannot be present, you can still run those labs at office or home using your own X86 machine by following the detailed documents.


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Yarn Profile: Malabrigo Chunky
First Impressions
The primary appeal of Malabrigo—all of the Malabrigo yarns—is the bright, often candylike colors that flicker in subtle variegation. These colors are achieved through a technique the Malabrigo folks call "kettle dyeing." The kettle is really just a large pot into which dye is added but not fully blended. I do not know if more dye is added after the yarn has been suspended into the kettle, but I'd guess so—at least for some colorways. A subtle variegation is achieved by not thoroughly mixing all the dye together. It can also cause significant color differences within the same dyelot, depending on where the skein sat in the dye pot.
If the colors lure knitters to Malabrigo, the soft fibers reel them in. Malabrigo uses extremely soft Merino fibers for most of its yarns. The fibers are spun loosely enough to keep a marvelous halo and decadent softness that really does feel like you're knitting with butter.
But just as butter melts if you work it too much, Malabrigo will pill if you wear it a lot. That's just a fact of life, and the sooner we surrender to this fact, the sooner we can move on and enjoy the yarn for what it is.
Having said that, there are some things that a yarn company can do to fortify its yarn—and adding multiple plies is one. I was curious to see if this is really true, and Malabrigo Chunky gives me a perfect chance to test this theory. It is composed of three plies, each of which is essentially a finer version of Malabrigo worsted. Would the plying really make it more durable? And would it simultaneously introduce any drawbacks that make this yarn less appealing than the single?
Knitting Up
Even on my cast-on row I could tell that this is a happy yarn. It likes to be held in your hands, and it enjoys being manipulated on the needles. The yarn quickly produced a plump, even, and equally happy fabric. Within two rows I was knitting by touch alone, the well-defined tips of my Denise Interchangeables making swift and snagless work of each stitch.
Malabrigo lists two possible needle sizes on the label: US 10 or 11. I urge you to swatch both and decide which fabric feels best to you. The tighter fabric will wear longer, but it will also be much firmer. The looser fabric has more flow and fluidity, but at the expense of wearability. Play with needle sizes as you swatch and find a happy medium that feels good to you—and only then find a pattern to match. If you cram this yarn into too small of a needle, you'll end up with a bulletproof sweater that stands up on its own.
Blocking / Washing
There was no change in stitch or row gauge, or in color. My swatch blocked back to perfect shape, drying to reveal a slight halo over the fabric surface.
In terms of these notorious pills, they began after quite a reasonable amount of sustained friction—more than with the single-ply Malabrigo, and I credit the plies here. Those pills began as very fine flecks that were, thanks to an ever-increasing surface halo, barely distinguishable except from up close. Even as the pills spread, they stayed low and firmly rooted in the fabric.
The reward for your suffering is an extraordinarily soft, plush, and spongy material without one iota of prickle to it. This yarn creates the very definition of "next to the skin" fabric.
A full sweater in Malabrigo Chunky will be exquisite as long as you exercise a little prudent planning. Because of the weight and potential density of the fabric, I'd recommend keeping your sweater relatively form-fitting. Stick with stockinette and ribbing, and avoid too many yarn-hogging cables. A large textured coat out of this yarn will weigh a ton, and the weight may cause the fabric to do funky things along the shoulder seams. On the other side of the coin, you could use this yarn for things you want to be heavy—for example, a decadent cabled throw.
Malabrigo Chunky renders ribbing beautifully, with the Merino keeping the ribbing very snug and bouncy while the well-rounded fullness of the three plies enhances the contrasting knit and purl rib rows. But you can also use this yarn for smaller lace projects that have been scaled to accommodate the larger gauge. One great example is Emilee Mooney's Foliage hat, which only requires one skein of Malabrigo Chunky to complete.
Yarn name
Malabrigo Chunky
Fiber content
100% Merino wool
3 to 3 1/2 stitches per inch on US 10-11 (5-8mm) needles
Average retail price
Where to buy online
Weight/yardage per skein
3.5oz / 104 yards (95m)
Country of origin
Manufacturer's suggested wash method
Hand wash, dry flat.
Review date
Color used in review
Apricot (72)
Wholesale distributor

subset: commoncrawl


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PeerGuardian is Phoenix Labs' premier IP blocker for OS X. PeerGuardian integrates support for multiple lists, list editing, automatic updates, and blocking all of IPv4 (TCP, UDP, ICMP, etc), making it the safest and easiest way to protect your privacy on the Internet.
Required OS: not specified
Tags: internet , utility , p2p , network
8 Opinions
If you look on the PG (mac version) forums, there is an update for Snow Leopard.
But looking through the posts, it seems to be clunkier than ever (people are unable to UNblock some IPs blocked mistakenly).
Use at your own risk. Personally, I haven't reinstalled it since Transmission integrated blocklists.
use www.opendns.com to block what you don't want. PG's lists haven't been updated in forever.
The Transmission nightlies now have built in blocklist support (but if you don't want to use the default, you have to mess with it a bit).
I'm sorry, but this app is just terrible. There's no way to block IPs for a specific application - you either block everything or you block nothing. This means you either a) have to edit your blacklists and whitelists to restore semi-normal internet access, or b) enable PeerGuardian only when you're running that specific application and disable it afterwards.
The problem with a) is that it requires you to spend hours (or even days) monitoring your logs and editing the blacklists and whitelists to get things working properly again. And the problem with b) is that you're still dealing with crippled internet access while it's running. Additionally, PG is set to run at startup and there's no way to disable this. So if you use it infrequently, every time you startup or restart your computer you have to load up the PG app and allow all connections (and disable the helper applications, unless you want to waste resources). Also, good luck trying to get PG completely uninstalled.
The only problem, AFAIK anyway, is that PG is really the only game in town. A couple of apps like Azureus have built-in IP filters, but unless you happen to already be using such an app, there really is no other option for IP filtering. Which sucks. Because I really hate Azureus. And PeerGuardian.
It looks like this might be one of those "lesser of two evils" situations...
Doesn't work yet with Leopard!
@ ahammond:
I use the feature "disable filters" whenevr I'm going to be remainn g on known, safe pages. Google and others get blakclisted because if you pull a P2P seed from them, you are likely to be suspected of somehting illegal and possibly harrassed / arrested / sued.
Other thna that, you can also create your own allow lists. I juts wish the lists could be speicifc for a particular protocol - let me browse to any site I want, block ftp protocols when in doubt. That's where I use Little Snitch.
I was very impressed with the writeup so I decided to install this app. The install was completely painless and easy, which left me greatly impressed. Unfortunately it looks like google is in the block lists loaded by default. Since I'm a huge google fan boy (mail, calendar, rss reader, maps, bookmarks, and obviously search) this was a bit of a problem for me. So I thought I'd just add an allow rule for google stuff. Hmmm... how do I do that? Google will tell me... oh... right. :(
Anyway, the uninstall script worked just as cleanly as the install. I'd love to use this tool, but default blocking of the most useful set of sites on the net kinda ruins things, at least for me.
Combined with Growl this is a perfect package. Runs unobtrusively in the background without the need to keep the actual app running. It's actually a lot better than the Windows-version of this. A monitoring widget is included.


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Used with permission of
Michelin North America, Inc.
December 11, 2007
I am looking for a personalized leather private pilot patch. I bought one several years ago and it looks great on my leather jacket. I now have a leather vest that I would like to put one on. I can't remember the web site I ordered it from. Any direction would be great. Thanks, Wyatt


text:
FiltersShow / Hide
- All Events
- Music
- Comedy
- Theatre & Shows
- Sport
- Cinema
- Festivals
- Days Out
- Edinburgh Fringe
- Anywhere In The UK
- Location: Anywhere in the UK
Radius: ... miles
Wed 27th Feb at 8:00pm
Post War Years
@ Komedia, Brighton
Also appearing: Nightworks
This event has been and gone!
Catch the next one:
Check out the info below for future tour dates, and track them to receive alerts when they tour near you
Never miss another 'Post War Years' show
Post War Years
Leamington Spa's finest, who deliver a unique and invigorating blend of electro, jazz, pop and rock.
Post War Years tour dates
Track this event
- Event has been added to your calendar
- Any important updates will be sent to your email address
- Add to your personal Ents24 calendar
- Sync with iCal, Outlook and others
- Receive important updates
Venue Facts
Venue: Komedia
Website: komedia.co.uk/brighton
Bookings: 0845 293 8480
Disabled Bookings: 0845 293 8480
→ Brighton 7 min walk


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THE BAD: Considering how well the band ripped apart the Bowie, set 2 is filled with somewhat minimal room to improvise (read Wilson, Fluffhead>Possum). Love You is funny, but it sure would've been nice to see more hey-jamming in the meat of set 2 (no complaints though!)
ETC: Several songs from this show appear on Youtube. Trey says hi to folks on the roof of the nearby building, adding "don't fall!". Trey introduces Fish as "a butt with protruding arms and legs" during I Didn't Know. Fish then plays a world-record "sparsest washboard solo ever". After Trey gives congratulations to the fan who makes 2 baskets in BBJ, the band teases R+R part 2. Fish asks if anyone actually knows the lyrics to the song. He also suggests that the band play that (but they don't). Fish calls Trey "Chuck Norris" when he introduces the band. Before Freebird, the band points out the "really big dude" in the front. You can see this guy in Youtube (he must be 6'9").


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I have followed the FAQ down to the letter but I still can't get PSM to show up on my PS3. I had it working before but I recently moved into a new home and I still have the same router but my computer is now hooked up through a switch instead of directly into the router like my PS3. Could that be causing the problem?
Here's my debug log: http://pastebin.com/rprk5bRj


text:
The Kidney Patients Support Group will meet from noon until 1 p.m. Saturday, July 20, at the Blessing Hospital Auditorium, 11th Street entrance.
The topic of the program will be understanding lab results.
Lunch will be provided at no cost. However, RSVP is requested by calling Lana Schmidt (217) 617-2888 or Ruby McGartland (217) 653-5439.
Location, ST | website.com


text:
Gain practical insight into the art of managing others. Obtain guidelines and techniques to successfully develop high-performing teams that get results. Practice management skills in class to reinforce key concepts in this hands-on course based on management models from Alessandra and Hunsaker's The New Art of Managing People and lessons from Buckingham and Coffman's First, Break All the Rules. Get the instruction you need to develop the unique skill set required to manage people effectively. Yields 15 PDUs.
Required textbook: The New Art of Managing People, by Hunsaker and Alessandra
Recommended textbook: First, Break All the Rules, by Buckingham and Coffman.
See our detailed course information including course content, learning objectives, and prerequisites.


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WHAT IS IT? A section of U.S. 61 in Hannibal was reduced to one lane on Thursday while trees were being removed from a steep hillside overlooking the busy highway.
Despite Thursday's rain, Missouri Department of personnel were busy trimming trees near U.S. 61 in Hannibal.
The work was focused near the near Fair Oaks Subdivision. Because MoDOT personnel were on the shoulder, southbound traffic was reduced to one lane from just south of the Steamboat Bend Shopping Center to Highway MM.
"Those trees were starting to lean pretty bad," said Simon Begley, maintenance supervisor. "We just wanted to get them down while the time was right before we potentially had wind or ice that would bring them down. We're being proactive, trying to get those trees that were leaning down safely."
Begley termed the undertaking a "major trimming."
"Hopefully it will last for quite a while," he said.
Begley praised motorists passing through the work zone.
"Traffic behaved very well. I was impressed," he said.
According to Begley, the hillside work will wrap up Friday.
Care to know more about something? Drop us a line at:
phone (573) 221-2800 e-mail email@example.com
fax (573) 221-5800 mail P.O. Box A, Hannibal, MO 63401
Location, ST | website.com


text:
I have many text object that every time I hade to change the contenet
like "company A" to "company B"
Is very time consuming change them 1 by 1 , any script or command I can use ??
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text:
BEST ENTRANCE: Legal Sea Foods Parking Lot
LOCATION IN MALL: Located across from the Nordstrom Wing
(978) 977-0085 | Driving Directions | Brookstone Website |
View Deals | Mall Map
More stores to consider
Be the first to own the latest... The @fitbit Charge 2 is now available for pre-order. https://t.co/lhAM03ILGt https://t.co/2Oqwi0G3SS/p>
Be the first to own the latest and stay motivated! The Fitbit Charge 2 is now available for pre-order. bit.ly/FitBitCharge2
Read More
Cooper doesn't worry about the ruff dog days of Summer https://t.co/JzTRw5MOg7 #nationaldogday https://t.co/yl9eveNtjj/p>
IIN STORES & ONLINE... Buy One, Get One 50% Off.... Limited Time Only... Exclusions Apply... Stay Cool This Weekend!
We want to congratulate Team Brookstone for finishing the Cigna/Elliot Corporate 5K Road Race. You braved the 97° heat with almost 6,000 other runners/walkers yesterday. We're so proud! Great job!
RT @sassyghostgirl: You know you're an adult when you get hyped over buying slippers from Brookstone and all you want to do is go home and…/p>
RT @4cast4you: . @Brookstone thanks! https://t.co/XfN8UocucF/p>
RT @shanrachael: My niece dancing at brookstone in the mall ?? https://t.co/4A1r3jPBdc/p>
We want to hear from you!
#Repost macynavi
I borrowed my friend's #catearheadphones. I think I'm in love. ?? #Cat… https://t.co/ivhQGMrkOH/p>
RT @ivy_saur2016: #NationalGirlfriendDay
Legit, these headphones are life @Brookstone https://t.co/QRkSbDgRr3/p>
RT @juustinne: They say the best things in life are free, for example going to Brookstone and getting a free massage in their massage chairs/p>
Genius ?? https://t.co/l3zWuLPrMU/p>
Transform your journey. Upgrade to first class with Sennheiser's PXC 550. Available EXCLUSIVELY in Brookstone Airports. More info here: http://bit.ly/BrookstonePXC550
RT @ethan_hallberg: only true ballers go to brookstone/p>
RT @BrandonBarash: Valentine's Day shopping is soooooo stressful. @Brookstone #brookstonemassagechairs #ineedone #likenow https://t.co/bq2D…/p>
We want to hear from you! https://t.co/5jUo7wIWcW/p>
RT @haystiplierlov1: #catheadphones https://t.co/p9HNEdT8Qm/p>
RT @CassidyCooley: When the hubby isn't home I steal his @Brookstone shiatsu massager that I got him(me) for Xmas #MerryXmasToMe #ILoveJesu…/p>
BOOM! https://t.co/2RERDeCSUO https://t.co/GaxfvOoqr8/p>
We love BauBax! http://bit.ly/BKSTbaubax
True olympic spirit.
Going up! Our new Brookstone store in Nanjing is on the 7th floor of the Xijinkou Department store—one of the largest department stores in China. Congratulations to everyone!
The 8 Best #Suitcases for the Constant #Traveler || Thanks for sharing @gangsta_leen https://t.co/hi8Nc14CZd via @xojanedotcom #travel #dash/p>
Tough Monday? Check out these products to help ease your pain.
Upgrade to first class with @SennheiserUSA's PXC 550. Available EXCLUSIVELY in Brookstone Airports. #sennheiser https://t.co/cAlP8EhrrP/p>
Upgrade to first class with @Sennheiser's PXC 550. Available EXCLUSIVELY in Brookstone Airports. https://t.co/9FW8l4GHnw/p>
RT @mandibosse: i just walked past brookstone in the mall and they were playing no scrub loudly so i started dancing & an employee started…/p>
RT @netterwald: @Brookstone is excited to launch the @SennheiserUSA pxc550 in #airport locations exclusively! #firstclass #today https://t…/p>
RT @brittailor: Love going to Brookstone just for the massage chairs, kinetic sand, and to charge my phone./p>
RT @iamsimplymina: Shoutout to @Brookstone for giving me a Pokemon Go discount when I forgot headphones for my flight. Amateur hour over he…/p>
Check it out! @markiplier is wearing our #CatEarHeadphones! https://t.co/w7Zj3ORJE0/p>
THIS is why we love @BauBax. Available here: https://t.co/DmyAGkiNYp https://t.co/xhXqmZLzjA/p>
RT @ellen_harvE: Someday I'm gonna be rich enough to buy everything in Brookstone/p>
RT @schenck1227: Just got $5 off at Brookstone because I play Pokemon ??/p>
THIS is why we love BauBax - Available here: bit.ly/BKSTbaubax
This pup has the right idea. How are you ending your #Monday? http://bit.ly/BKSTshiatsu
This is amazing! Thanks for letting us know! https://t.co/4VSe7TJYgj/p>
Cooper doesn't worry about the ruff dog days of Summer because he has his Kai pool float http://bit.ly/KaiPoolFloats
Thank you, Jamie Baran, for putting a smile on our faces with this picture! #NationalDogDay
RT @ASAP_Maki: Brookstone got good taste in music @thatPoppy https://t.co/68BYJlOdf7/p>
Our new Brookstone store in Nanjing is on the 7th floor of the Xijinkou Department store—one of the largest in China https://t.co/lJfmA5JtrZ/p>
It's #NationalRelaxationDay! Try our massage chairs in person at a store near you. Feeling is believing. http://bit.ly/SignatureMassage
You could if you stopped by our store and relaxed in a massage chair. https://t.co/I9UBQGIg3w/p>
We bet you didn't know that today is National #PlayInTheSandDay! Have you tried our Sand? https://t.co/PI8xtdTg3H https://t.co/8vjZGqecAS/p>
20% OFF 48 Hours ONLY! #BackToSchool https://t.co/N2ngSG8OLk https://t.co/UDJpwjttuO/p>
Happy #NationalBeerDay!
Make sure the next round is on someone else... https://t.co/kEBBZc5qZB/p>
...as it should be spent. https://t.co/0xCrnMkT0z/p>
We love @BauBax! https://t.co/e9Xm2taTre https://t.co/h4d1rjbizF/p>
The Eluma Cube is a must have at your next BBQ. Hurry! Get it before the Summer ends! bit.ly/ElumaCube
RT @robertkelly: @UFC @Brookstone mini projector #outside #smoking #cigars https://t.co/Yzcvf9v3kR/p>
RT @fuller_mj: Love the sand from @Brookstone Keeps the kids busy for hours! https://t.co/QBPSOmzYSu/p>
IIN STORES & ONLINE... Buy One, Get One 50% Off.... Limited Time Only... Exclusions Apply... Stay Cool This Weekend! https://t.co/xPhyd09Ryk/p>
We had lots of fun riding on the CityBug2 E-Scooter. Available only at Brookstone: http://bit.ly/CityBug2
Yikes, 1 in 4 marriages today end up without enough luggage. Don't let this happen to yours. http://bit.ly/2bvF7bm
It's #NationalRelaxationDay! Try our massage chairs in person at a store near you. https://t.co/THcsjeqNsT https://t.co/p6yaiFZGKf/p>
Show us your sand sculptures! It's National Play in the Sand Day bit.ly/PlayintheSand
RT @Victoria_Is: The sales associates at @Brookstone in Terminal T at ATL are heroes: throwing a dance party for all the delayed #DeltaDown…/p>
RT @rukes: Which DJ is gonna be the first to use these cat ear headphones on main stage? https://t.co/nnH8r4xTWs/p>
Happy #NationalBeerDay!
Tag someone who owes you a beer...
RT @nickcarter: I was sitting in a massage chair in the mall at @Brookstone doing a Skype chat with a fan from Japan. ?? https://t.co/MdNYX6…/p>
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text:
Category:Fischer, Kurt von
Free public domain sheet music from IMSLP / Petrucci Music Library
|All works by this person are still under copyright in Canada, the EU, Japan, and elsewhere and are thus subject to deletion. The works are also probably copyrighted in the U.S. if first published after 1923. (See public domain.) An exception is if the person or copyright holder allows IMSLP to use the works in a manner similar to a work in the public domain. If this is the case, please choose the "Creative Commons" or "Performance Restricted" license instead of "Public Domain" when submitting the file (or edit it to such, if already submitted). In such cases, it is necessary to put a copyright notice with the copyright type somewhere in the file, to prevent confusion.
Kurt von Fischer(25 April 1913 — 27 November 2003)
→Table of Contents: Top - A B C D E F G H I J K L M N O P Q R S T U V W X Y Z - Chart
xShow works by type/instrument
=Alternative Names/Transliterations: Curt von Fischer
External links
- Detailed biography: None given
- Recordings: None given
Miscellaneous information
As Editor (35)
Works edited by: Fischer, Kurt von
The following 35 pages are in this category, out of 35 total.


text:
Northern Mariana Islands Quarter
The last quarter to be released under the District of Columbia and U.S. Territories Quarters Program is the quarter that honors the Northern Mariana Islands. The 2009 Quarters page explains the images on the coin and gives you some of the history that brought these islands into their status as a territory of the United States.
As Coin of the Month, I'd like to take a look at what's happening "behind the scenes"…or should I say "UNDER the scenes"?
You see, according to the National Aeronautics and Space Administration (NASA), it was underwater volcanoes that formed the Mariana Islands. The islands lie along the edge of a huge patch of Earth's crust called the Philippine plate. East of the Marianas, the Pacific plate (under the Pacific Ocean) meets the Philippine plate. As the two plates collide, the Pacific plate gets pushed down under the Philippine plate, creating the Marianas Trench, the deepest ocean that we know of on the whole planet (more than 35,000 feet deep).
As the plates grind against each other, rock breaks up, causing heat and building pressure. Through cracks in the upper plate, lava rises and bursts through the crust. If this happens under water, the cooled lava creates undersea mountains called "seamounts." The mountains sometimes keep erupting and grow until they get higher than the water's surface. Then you have a volcanic island. All of the Marianas formed in this way.
The 14 islands of the Northern Marianas host nine active volcanoes. One volcano, on the island of Anatahan, was considered dormant (inactive) because there was no record of it erupting…until 2003. Anatahan's volcano has erupted several times since then, which just goes to show: you never know with volcanoes!
Volcanoes can cause much destruction with their falling rock and flowing hot lava, but one force you might not think about is clouds of ash that rise into the air and drift for miles. This ash can damage airplanes that fly through it, causing engines to suddenly stop running and equipment to stop working properly. One of Anatahan's plumes rose 50,000 feet! The ash plume from Anatahan's 2003 eruption was so huge it was photographed from the International Space Station!
Another problem with eruptions is that they're hard to predict. No people have been hurt during Anatahan's eruptions because no one lives on the island anymore, but weather scientists learned something from Anatahan: radar equipment, made to measure clouds, can also measure plumes of ash from volcanoes. Anatahan sent up plumes right before it erupted in 2003, which the radar detected. Because of this, pilots were warned to steer clear of the area, keeping their flights safe.


text:
Hydar Ali
Graduate Group Affiliations
Contact information
Robert Schattner Center
346 Levy Building
240 South 40th Street
Philadelphia, PA 19104
346 Levy Building
240 South 40th Street
Philadelphia, PA 19104
Office: (215) 573-1993
Fax: (215) 573-2050
Fax: (215) 573-2050
Education:Permanent link
University College London, England, 1982.
Ph.D. (Immunology/Pharmacology)
University of London, UK, 1986.
University College London, England, 1982.
Ph.D. (Immunology/Pharmacology)
University of London, UK, 1986.
Description of Research ExpertiseResearch Interests:
Mast Cell Signaling in the Regulation of Allergic Diseases such as Asthma and Anaphylaxis
Research Summary:
Asthma is a chronic inflammatory disease, which is associated with the recruitment of mast cells to the lung and their activation. It is well known that aggregation of high affinity IgE receptors (FcepsilonRI) on mast cells and the subsequent mediator release contributes to the development of allergic asthma. However, emerging evidence suggests that transactivation of G protein coupled receptors (GPCRs) for the complement component C3a contributes to the exacerbation of allergic diseases. The main focus of our laboratory has been to delineate how G protein coupled receptor kinases (GRKs) and the adaptor molecule β-arrestin regulate C3a receptor function in mast cells. We unexpectedly found that GRK2 and β-arrestin2 serve as novel adaptor proteins to promote IgE-mediated mast cell chemotaxis, degranulation and cytokine gene expression. We are currently utilizing both in vitro and in vivo approaches to delineate how GRK2 and β-arrestin2 regulate FcepsilonRI signaling in mast cells to modulate allergic asthma.
Surface epithelial cells, when activated by pathogen-associated molecular patterns (PAMPs) release small cationic antibacterial peptides (AMPs), known as defensins and cathelicidins. These AMPs display potent antimicrobial activity, modulate immune responses and likely participate in the exacerbation of allergic diseases such as asthma and urticaria. Recently, we made the unexpected observation that AMPs activate human mast cells via a novel GPCR (Mas-related gene X2; MrgX2). Most interestingly, we found that unlike C3a receptor, MrgX2 is resistant to regulation by GRK2 or β-arrestin-2. It is noteworthy that unlike human mast cells, murine mast cells do not express MrgX2 and are resistant to activation by AMPs. We are currently engrafting human CD34+ hematopoietic stem cells (HSCs) into severely immune-deficient mice. In addition to human immune system, these "HUMANIZED MICE" develop human tissue mast cells are responsive to AMPs for activation in vivo. We are currently using the humanized mouse model to determine the role of MrgX2 and its signaling on anaphylaxis and asthma in vivo.
Selected PublicationsSubramanian, H. Gupta, K. Parameswaran, N. Ali, H.: Regulation of Fc[epsilon]RI signaling in mast cells by G protein coupled receptor kinase-2 and its RH domain. The Journal of biological chemistry DOI:10.1074/jbc.M113.523969, June 2014.
Subramanian Hariharan, Gupta Kshitij, Lee Donguk, Bayir Arzu K, Ahn Harry, Ali Hydar: β-Defensins activate human mast cells via Mas-related gene X2. Journal of immunology (Baltimore, Md. : 1950) 191(1): 345-52, Jul 2013.
Subramanian Hariharan, Gupta Kshitij, Ali Hydar: Roles for NHERF1 and NHERF2 on the regulation of C3a receptor signaling in human mast cells. PloS one 7(12): e51355, 2012.
Gupta Kshitij, Subramanian Hariharan, Klos Andreas, Ali Hydar: Phosphorylation of C3a receptor at multiple sites mediates desensitization, β-arrestin-2 recruitment and inhibition of NF-κB activity in mast cells. PloS one 7(10): e46369, 2012.
Subramanian Hariharan, Gupta Kshitij, Guo Qiang, Price Ryan, Ali Hydar: Mas-related gene X2 (MrgX2) is a novel G protein-coupled receptor for the antimicrobial peptide LL-37 in human mast cells: resistance to receptor phosphorylation, desensitization, and internalization. The Journal of biological chemistry 286(52): 44739-49, Dec 2011.
Kashem Sakeen W, Subramanian Hariharan, Collington Sarah J, Magotti Paola, Lambris John D, Ali Hydar: G protein coupled receptor specificity for C3a and compound 48/80-induced degranulation in human mast cells: roles of Mas-related genes MrgX1 and MrgX2. European journal of pharmacology 668(1-2): 299-304, Oct 2011.
Subramanian Hariharan, Kashem Sakeen W, Collington Sarah J, Qu Hongchang, Lambris John D, Ali Hydar: PMX-53 as a dual CD88 antagonist and an agonist for Mas-related gene 2 (MrgX2) in human mast cells. Molecular pharmacology 79(6): 1005-13, Jun 2011.
Kashem, SW, Subramanian, H., Collington, S Maggoti, P, Lambris, JD and Ali, H. : G protein coupled receptor specificity for C3a and compound 48/48-induced degranulation in human mast cells: roles of Mas-related genes MrgX1 and MrgX2. Eur. J. Pharm. 668: 299-304, 2011.
Vibhuti, A., Gupta, K., Subramanian, H, Quo, Q and Ali, H. : Distinct and shared roles of β-arrestin-1 and β-arrestin-2 on the regulation of C3a receptor signaling in human mast cells. PLoS ONE 6(5): e19585, 2011.
Guo, Q, Subramanian, H, Gupta, K and Ali, H. : Regulation of C3a receptor signaling in human mast cells by G Protein coupled receptor kinases. PLoS ONE 6: e22559, 2011.
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Last updated: 07/23/2014
The Trustees of the University of Pennsylvania
Last updated: 07/23/2014
The Trustees of the University of Pennsylvania


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A 20-year-old woman is being held in the Jackson County Jail on over $500,000 bail after local and federal police say they caught her smuggling about 3 pounds of methamphetamine through the Rogue Valley inside a fire extinguisher Monday.
Police reported Maria De Jesus Beltran-Leon, 20, no address given, is held in the jail on charges of unlawful delivery and possession of a controlled substance, with bail set at $510,000.
Officials from the Medford Area Drug and Gang Enforcement — MADGE — Team, received a tip about Beltran-Leon's whereabouts, directing police to a public bus passing through Phoenix. The agency received assistance from U.S. Immigrations and Customs Enforcement and Homeland Security Investigations. Police said they found Beltran-Leon on the bus with the fire extinguisher and arrested her after finding the drugs inside the fire extinguisher.
Calls to MADGE were not immediately returned. We'll have more on this story as it becomes available.
— Ryan Pfeil
Location, ST | website.com


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22 December 2014
Gavi and Ebola - FAQ
Gavi and Ebola - Frequently asked questions.
18 August 2014
GAVI HSS Grant Categorisation 2014
This table is intended to provide ideas of HSS activities to applicants and to allow GAVI to analyse its HSS support by type of grants.
01 July 2014
GNI per capita 2013
Gross national income per capita 2013.
31 March 2014
HSS Country ceilings
Country ceilings and maximum annual amounts for budgeting for GAVI Health Systems Strengthening (HSS) grant applications.
10 March 2014
Delivering results in HSS information sheet
Information sheet about measuring results for health system performance and improving data quality.
Guidance on GAVI HSS approach and application process
Health system strengthening approach information sheet.
Performance Based Funding information sheet
Information sheet about GAVI's HSS Performance Based Funding.
Human Papillomavirus vaccines information sheet
Human Papillomavirus vaccines information sheet.
Japanese Encephalitis vaccines FAQ
Japanese Encephalitis vaccines Frequently Asked Questions.
Ethics hotline
Concerned about the misuse of Gavi resources? Report it now.
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Lord Odin from the A5 Operator's Group wrote this well thought out and thorough paintball gun comparison pitting the Tippmann A-5 against the Tippmann 98 Series guns.
The Tippmann A-5 is the next generation of markers after the Tippmann 98 with a few major differences. On average, they cost a bit more, but for about $50, you get a superior marker.
The first major upgrade is the Cyclone feed system built into A-5 marker. Tippmann has done away with the vertical feed and have added a pneumatic force feed system that virtually eliminates jams. Unlike electronic loaders, there are no batteries and force is only applied to the balls when the gun cycles. Due to the large opening of the Cyclone, it eliminates jams in the feedneck that can happen on the 98 Custom and any other small feed neck gun. The Cyclone has a lower profile than traditional hoppers, which is ideal for woodsball because players will mostly pop up over something than off to the side. Reducing your silhouette reduces your chance of getting shot.
Tippmann has also made the gun more accessible by including pushpins for commonly removed items. Rather than completely disassembling the marker like on the 98's, you can now remove pushpins to access your optional E-grip, remove your internals to lubricate or fix a problem, or change stocks. The A-5 lets you completely remove your trigger and grip. This is important if your trigger is malfunctioning or if it starts to rain and you want to switch back to a mechanical grip. The front grip is also removable, which gives you more options of style and placement on the marker.
The internals of the A-5 gun are very similar to the 98 Custom with one major exception. The A-5 now makes use of a tombstone. This is a piece that slides into the gun from the outside and is locked into place but is easily removable. On the 98's, a braided hose was screwed directly into the valve body and was not easily removed unless in the staging area. The Tombstone on the A-5 allows for easier disassembly and gives you more upgrade options. Now you can mount a regulator directly to the gun, move locations of your gas line, or even connect a remote line directly. And all of this is done easily by attaching it to the tombstone with your hands. No tools are necessary to connect components to the tombstone or the tombstone to the gun.
The A-5 now has completely enclosed internals. The 98 Custom had its cocking handle connected to the hammer, which exposed your internals to dirt, paint, and other debris. On the A-5, the cocking handle has been relocated and the internals closed off, which will make your gun operate better and cleaner. Parts such as o-rings will need less replacement, as well.
The A-5 comes with a different barrel threading than the 98 Series guns. One of the complaints of 98 users was the barrel twisting loose on them due to the steep threading. The gradual threading of the A-5 barrels requires more turning to remove the barrel. This creates a tighter fit and it is much less likely to unscrew.
Lastly, manufacturers are producing many more upgrades and accessories for the A-5 instead of the 98 series, which seems to be taking a back seat to the A-5. This gives you many more upgrade options when you choose the A-5 and many of them are easy to install with the quick release pins.
For the little extra money, the A-5 is big step up from the 98 and is well worth price.
-Thanks for the review Lord Odin! An abbreviated version of this comparison has been incorporated in to our Tippmann A-5 Buyer's Guide. TippmannParts.com carries the full line of Tippmann A-5 and 98 Series Paintball Guns in stock at the best prices.


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Samantha Ryan was very excited to ride the Sybian! It didn't take long for her to insert that hard cock into her pretty little pussy and ride. She cranked up the speed and the rotation, because that is how she wanted to cum. She played around with her beautiful perky breasts and nipples as she started to cum... her eyes rolled back in her head! Now that is a little piece of heaven.
Samantha Ryan is dolled up and going to hit the LA scene with her girlfriends. She is looking for a guy to hook up with and I am sure they are always standing in line waiting for her. She doesn't want to go out super horny so she "rubs one out" first with her favorite pink vibrator. NOW she is ready to go out and feeling fine. Sit back and enjoy this super sexy masturbation video!
The blode bombshell Samantha Ryan is horny and is having a hard time keeping her hands off herself!! She touches her hot body to turn you on, make you sweat a little bit. She shakes and slaps that awesome ass in her tight shorts, she asks for a spanking. Her fingers slide inside her panties and she fingers her pussy until she gets nice and wet. Now she is 100 percent ready for your cock to fuck her.


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Gay Marriage Rulings: A Cheat Sheet
Q: Can people in gay marriages now receive the same federal benefits as people in opposite-sex marriages?
Yes. The Supreme Court struck down as unconstitutional a part of the Defense of Marriage Act that denied federal benefits to gay and lesbian couples in states where such unions are permitted.
Here's a partial list of the 1,000-plus provisions of U.S. law in which federal benefits are contingent on marital status, or in which marital status is a factor.
Q: Do today's rulings mean all states have to allow gay marriage?
No. The justices declined to say whether bans on gay marriage are constitutional.
Q: Did the court approve gay marriage in California?
No. The court ruled that it lacked jurisdiction to consider the matter. After a lower court struck down Proposition 8, California's voter-mandated ban on gay marriage, state officials declined to bring an appeal. So proponents of the ballot measure tried to carry the appeal on their own, but the Supreme Court said they couldn't do so.
Q: So what does that mean for the Golden State?
It's complicated. The Supreme Court's ruling means that a 2010 lower federal court ruling invalidating Prop 8 stands. But the California Supreme Court upheld Prop 8 in 2009.
Proponents of Prop 8 could still argue in federal court that the 2010 ruling applies only to the four couples who challenged the ballot measure, but they would run into the same standing issues cited in today's ruling, according to Hunter T. Carter, a partner at Arent Fox LLP and proponent of same-sex marriage.
So, Mr. Carter said, the tension between the two rulings means the fight will continue in state court, where proponents of the ballot measure do have standing.
Mr. Carter predicted that California officials would embrace the Supreme Court's ruling Wednesday and announce that gay marriage in the state is legal. Law Blog is awaiting statements from the governor and attorney general.
Update 2:20 p.m. Gov. Jerry Brown said he would instruct counties to start handing out marriage licenses to same-sex couples as soon as possible.


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ALAMEDA -- The numbers say that Darren McFadden is about half the running back he was a year ago.
Raiders coach Dennis Allen was asked Monday if McFadden looks like the same player he saw on film from 2011.
"Yeah, he does," Allen said. "He's still an explosive player. We've got to do a better job creating room for him to run. We've incorporated a few more of those gap-scheme plays, and I know you can say this on every play, but we're one block here or there from a big run."
In a 26-23 win overtime win over the Jacksonville Jaguars Sunday, McFadden gained 53 yards on 19 carries in what was very close to the norm for him this season. With 324 yards on 103 attempts, McFadden is averaging 17.2 carries and 54 yards per game rushing.
At this point last season, McFadden was the hottest back in the NFL with 111 carries for 610 yards.
But in Week 7 against the Kansas City Chiefs, McFadden carried twice for 4 yards, twisted his foot awkwardly after catching a short pass from Jason Campbell, and was out for the rest of the season with a Lisfranc sprain.
The Raiders (2-4) are facing the Chiefs again in the seventh game, this time in Arrowhead Stadium.
McFadden has politely fielded inquires every week about the struggles of the running game. Other than an 18-carry, 113-yard effort against Pittsburgh, it's been slow going.
Although listed with a shoulder injury, McFadden said he's fine physically. A quick trip to the locker room against Jacksonville was for a bathroom break. He said he's reviewed every carry to see if there is anything he is missing.
"You want to look at every run, so you can know what you did wrong or if you should have stayed with the hole or made an earlier cut," McFadden said. "It's one of those things where you have to go back and re-evaluate yourself."
Given the Raiders commitment to a zone blocking system, the addition of power and gap-scheme runs were a bye-week tweak designed to get McFadden going. Former offensive coordinator Hue Jackson added those running plays in 2010 after conferring with McFadden.
Allen likes what he sees from McFadden getting tough yards, and believes McFadden's breaking a run or two every game will get things back to normal.
"You look at the Pittsburgh game, and his best rushing output and he had an explosive (64-yard) run," Allen said. "That's how you get those big games. You have one or two explosive runs, and all of a sudden you look up and here's a guy with a hundred-and-something yards rushing."
"I don't know how they'll respond to it," Allen said. "I don't see them changing a whole lot as far as philosophically what they're going to do on offense."
Tackle Khalif Barnes (groin) and cornerback Shawntae Spencer (foot) are doubtful to practice, Allen said, but tight end Richard Gordon (hamstring) could return to the field, Allen said.
Cornerback Ron Bartell (broken scapula) is eligible to come off the designated for return injured reserve list Saturday, meaning he'll probably practice next week.


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VINCENT - Warren will be on unchartered hardwood when it plays Akron St. Vincent-St. Mary in an Ohio Division II state semifinal boys' basketball game at Value City Arena on the campus of The Ohio State University at 5:15 p.m. Thursday.
The Warrior cagers, 26-1 overall with a 21-game winning streak, are looking forward to the experience.
"It's just so good to go and play at Ohio State with all the people watching," said Warren junior sharpshooter Evan French. "It's great for the community to go out there and represent them good.
Article Photos
Photo courtesy of Robin Pannell
Warren's Adam Lang, left, and Matt Drayer, third from left, play tight defense against Jackson in an SEOAL game during the regular season. The Warriors are scheduled to play Akron St. Vincent-St. Marys in a state semifinal at Value City Arena Thursday.
Photo courtesy of Robin Pannell
Warren's Reece Patton goes in for a layup against Marietta in a non-conference game during the regular season. The Warriors are scheduled to play Akron St. Vincent-St. Marys in a state semifinal at Value City Arena Thursday.
Photo courtesy of Robin Pannell
Warren's Evan French, left, drives to the basket against Portsmouth in an SEOAL game during the regular season. The Warriors are scheduled to play Akron St. Vincent-St. Marys in a state semifinal at Value City Arena Thursday.
"I love my teammates. They're everything to me, and it just feels so good to be going to state. It's been something we've been working for all year."
Veteran Warriors head coach Blane Maddox added, "It's unbelievable. This is awesome for our community. It's wonderful. The students get out early, I think, Thursday.
"I know that whatever happens, we will represent southeastern Ohio basketball and Washington County with class."
Said Warren senior Dylan Leffingwell, "It's just the greatest feeling that you could ever imagine. I mean, state, Schottenstein (Value City Arena), what's better than that? Nothing."
Warren got to the Final 4 by virtue of its dramatic 49-47 triumph over New Philadelphia in a regional final at the Ohio University Convocation Center in Athens Saturday. Evan Yabs' putback score at the buzzer sealed the deal.
"I was on the right wing, and Dylan attacked (the basket) - and he had a couple of guys going at him," said the 5-foot-9 Yabs of his only two points of the contest. "My man left me, and I was just wide open there for the putback."
Said French, "It actually reminded me of couple of years ago when we were in the district final against Chillicothe. The same thing happened to us.
"I was just so happy when that happened (Yabs' putback). It was great."
French, a recent All-Ohio honoree, paced the Warriors with 21 points. Reece Patton added 15 markers.
Against STVM, Warren's fifth starter is expected to by 6-5 sophomore Michael Hall, who scored a team-high 21 points in the district final win against Vinton County.
Danny Pannell and Adam Lang will be the first Warriors off the pine.
"We have always said all along that we are a team of more than one," Maddox said. "We're a whole unit."
Unlike Warren, St. Vincent-St. Marys (19-9), a private co-ed Catholic prep school, is no stranger to the Final 4 in Columbus. The Irish have claimed seven state titles (1929, 1984, 2000, 2001, 2003, 2009 and 2011) in their storied history on the basketball court.
In 2003, STVM was the USA Today National Champion.
One of the school's most notable alumni is current NBA and Miami Heat super star LeBron James.
"LeBron's old team (St. Vincent-St. Marys)," Leffingwell said. "You know, we're all into that Twitter and stuff. So, we might be tweeting him all day to see if he's going, or just try to get him to respond to see if we can beat his team."
The Dru Joyce II-coached Irish got to state by staging a second half rally to beat the Warrensville Heights Tigers (17-11) 57-48 in a regional title tilt at Canton Memorial Civic Center Saturday.
St. Vincent-St. Marys trailed 27-24 at the intermission, but regained the advantage 33-27 at the end of the third - and never looked back.
STVM was led by 6-6 senior forward Nick Wells, who recorded a double-double with 21 points (15 in the second half) and 13 rebounds. The Lake Erie College recruit also had three swats, one steal and one assist.
VJ King, a 6-7 freshman guard, added 11 points, four caroms and two blocks. Jalen Hudson, a 6-6 junior backcourt player, had seven markers, three boards, two swats, and two steals.
Jarel Woolridge, Travonte Junious, Jordan Hargrove and Fransohn Bickley combined to score 18 points for the Irish winners.
STVM had trouble against Warrensville Height's uptempo offense, especially in the second quarter. But when the Irish switched to a 2-3 zone in the third period, they were able to slow the Tigers down.
Warren is very capable of any style of play on the hardwood, transition or halfcourt. If the Warriors face a 2-3, they have zone-breakers galore, including 6-2 pivot player Leffingwell, who knocked down one three in the win against New Philadelphia.
If it's man-to-man, French, Patton, Hall and Lang are all good one-on-one players. And, Leffingwell is fearless with the ball and will attack the basket no matter who's on him - and that's a good thing, because that's how a player can draw fouls.
Warren probably won't be facing any STVM player in the paint as strong as New Philly's 6-6 Ethan Boose. But the Warriors will still be undersized a little bit in that area as the Irish have good length and at least three shot blockers 6-6 or taller.
The royal blue and white cagers will definitely have to play good help defense, which they do very well anyways, and also box out on the glass.
Warren will also have to take care of the basketball. Against the Quakers, the Warriors had 12 turnovers, including 10 after the break.
"We had too many turnovers against New Philly," Maddox said. "That's what gave them a chance to get back in the game."
Both Warren and St. Vincent-St. Marys are expected to be nervous before the opening tip-off. That's actually normal, but once the game begins, those jitters and butterflies in the stomach should disappear.
A good start in the game is always preferable to a bad one as no team wants to be climbing out of a hole, or in a catch-up mode.
A good start is also good for the confidence.
Warren is counting on its royal blue and white faithful to make lots and lots of noise at Value City Arena. If the fans aren't hoarse at the end of the game...well, let's just say they just can't sit there on their hands. If they can't hear themselves think then they've done their job.
Warren High will be closed Thursday as five busloads of students are expected to be on the highway to Columbus.
The Warriors' spring break has been shortened by one day.
Also helping with the noise level at the arena will be the Warren pep band under the direction of Courtney Clark.
"It'll be the best experience that we'll ever have," said Leffingwell smiling. "It's a great opportunity for southeast Ohio to get out and go see, hopefully, a really good game."


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Market booster
23.04.2013 - Oern Stuge has taken over from Henry Hyde Thomson as Chairman at Phagenesis plc (Manchester) to support the rollout of the company's dysphagia therapy Phagenyx.
Stuge previously served as Senior Executive at Medtronic and Abbott Laboratories. He began his career as a practicing physician. He has an MD from the University of Oslo, as well as an MBA from IMD in Lausanne.http://www.european-biotechnology-news.com/people/bio-people/2013-01/oern-stuge.html


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The National Zoo is involved with cognitive research on great apes, giant pandas, sloth bears, other ursids, as well as variety of other species.
The cognitive research conducted at the National Zoo occupies a unique niche within the Smithsonian Institution as well as within the broader museum and zoological communities. more
Our youngest male elephant, Kandula, is the subject of an exciting cognition study. Elephants are known to have the ability to understand relationships and solve problems based on that knowledge, a trait known as "insight," is so impressive that researchers have been forced to rethink common assumptions regarding elephant intelligence altogether. Elephants have always been considered quite smart, but they've never before shown this ability to researchers in a quantifiable way. Read about the study
A ground-breaking exhibit tackling the complex field of animal cognition, Think Tank challenges us to ponder how primates and other animals process the world around them.
Several different cognitive research projects are occurring with the Zoo's great apes which can be seen in one of the daily research demonstrations at 1:30 p.m. Visitors may learn about metacognition, orangutan memory, or how apes learn to find and modify tools. The cognition research field with great apes is always changing, and Think Tank is the place to learn more about it.
That's one question that Lorie Tarou, Research Assistant for Giant Panda Behavior Studies, is interested in trying to answer. It may sound simple, but because of the pandas' unique categorization as an herbivorous carnivore, the usual assumptions about foraging are impossible to make. Herbivores can often return to certain spots to find food sources, and have adapted with good spatial orientation and memory for foraging.


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Deeplinks Blog posts about Bloggers' Rights
Today mobile software company Carrier IQ withdrew (pdf) a bogus legal threat to a security researcher who published an analysis of the company's software, as well as training materials on which he based his research.
Last week, Trevor Eckhart published a detailed article pointing out that Carrier IQ's software logs a great deal of information about users' activities without their knowledge. Attempting to suppress his research, Carrier IQ fired off a baseless cease-and-desist demand (pdf) claiming that Eckhart infringed the company's copyrights and made "false allegations" about their software.
Last week, security researcher Trevor Eckhart posted an analysis of software produced by Carrier IQ, which describes itself as "the world's leading provider of Mobile Service Intelligence solutions." Eckhart concluded that the software, which comes by default on many mobile devices and runs quietly in the background, logs extensive details about users' activities. Eckhart not only documented the functionality of the software, but learned even more about how it works through training materials posted on the Carrier IQ website. Fearing the company would take the files offline after he posted his analysis, he mirrored the training materials to let others independently verify his conclusions.
In early September, EFF was among the first to report on evidence published by activist collective Telecomix that Blue Coat technology was being used by the Syrian government to conduct surveillance. Following a release of more detailed log files as well as a more detailed report from our friends at Global Voices Advocacy, Mother Jones produced a detailed report, followed shortly by other publications. Prominent security expert Bruce Schneier then offered his take, stating: "Bet you anything that the Syrian Blue Coat products are re
One of the most grave threats to free expression in many countries these days is the intimidation and persecution of bloggers and online journalists. The effects are often far-reaching as bloggers are scared into silence. While the Arab Spring has brought about many positive changes throughout the region, several Middle Eastern countries continue to take measures to silence bloggers. This issue is not, of course, limited to the Middle East. In Thailand, web editor Jiew still faces up to fifteen years in prison, while US-Thai citizen Joe Wichai Commart Gordon pleaded guilty on charges of lèse majesté--a charge that can result in a prison sentence of up to fifteen years--and faces sentencing on November 9. In Mexico, bloggers and online activists may face an even worse fate.
Egypt: Free Maikel Nabil Sanad
EFF has grave concerns about the health of Egyptian blogger Maikel Nabil Sanad, who has now been on hunger strike for 57 days. Sanad's retrial was scheduled for October 13, but was postponed. Sanad, who was sentenced in April by a military court to three years in prison on charges of insulting the military on his blog, has stated that he will boycott any retrial.
We firmly support the statement made by Reporters Without Borders Wednesday, which reads:
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WordPress has so many options that every once in a while I wish I could just simplify things a bit. Well, this post form WordPress can help. By accessing your "Screen Options" you have the ability to choose what options show on your post pages.
See the instructions on this WordPress Post.
Happy Wednesday.


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About the Book
The classic story of Sleeping Beauty has had us believing so for years. Now, spun as if by magic from the threads of the beloved Brothers Grimm fairy tale comes the enchanting memoir of fashion designer Christian Lacroix—the haute couture icon whose creations have invited millions of women to enjoy the fairy princess fashions of their dreams. Sorcery and style combine in this enchanting new twist on a time-honored tale; re-imagined by international bestselling author Camilla Morton, and illustrated by Monsieur Lacroix himself, the spell cast by Christian Lacroix and the Tale of Sleeping Beauty will reawaken every reader's childhood fantasies—reassuring you that dreams really do come true…
About the Fashion Fairy Tale Memoir Series
Each book in this inspired series from fashion writer Camilla Morton inventively reimagines one of our favorite "Once Upon a Time" stories, blending with it the real-life story of a famed fashion designer. Lushly illustrated by the designers themselves, these tales illuminate each iconic individual's creative magic while celebrating his unique life and career. The result is an intriguing combination of whimsy and memoir.
In this contemporary twist on the tale of Sleeping Beauty, Monsieur Lacroix exercises a stunningly diverse array of artistic styles, revealing many more mesmerizing sides to his fertile imagination than those we have already seen in his magnificent fashions.
Educator and Librarian Resources
Product Details
- Imprint: Dey Street Books
- On Sale: 02/01/2011
- Trimsize: 6.25 in (w) x 8.75 in (h) x 0.507 in (d)
- Pages: 112
- List Price: 21.99 USD
- BISAC1: DESIGN / Fashion & Accessories
- BISAC2: BIOGRAPHY & AUTOBIOGRAPHY / Artists, Architects, Photographers


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Share Photo
Sandra Cavender reads to her daughter, Emilia Cavender during a book drive and fundraising event in honor of the Sandy Hook victims. Donated books and money will go to a local childrens charity, the San Diego Center for Children. 11 children's authors were on hand to sign their books.
— James Gregg


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Thanksgiving Recipes
Updated: 11/18/2014 - Check out some tasty recipes to try for your Thanksgiving Day feasts - and a few recipes to try for all those leftovers!
Updated: 11/18/2014 - Check out some tasty recipes to try for your Thanksgiving Day feasts - and a few recipes to try for all those leftovers!
Updated: 11/18/2009 - .
Posted: 09/28/2009 -
Updated: 09/30/2010 - Shop around for spooky tunes and you'll be able to create a great atmosphere for Halloween night.
Updated: 09/30/2010 - none
Updated: 09/30/2010 -
Updated: 09/05/2013 -
Updated: 09/30/2010 - From family favorites to slasher movies, there's something here for everyone to enjoy. If you're looking for some movie ideas for Halloween night, try the list below!
Updated: 09/30/2010 - Before your ghosts and goblins trick or treat this year, parents should keep in mind these safety tips to make sure the only howls are those of fun. What Works for You? Comment Below!
Posted: 05/26/2009 - A visual look at summer fashions for 2009!
Updated: 05/26/2009 - Check out the latest and greatest flicks to hit the big screen this summer!
Updated: 06/17/2011 - Whether you're on a tight budget, staying close to home, or are saving up, there is something for young and old!
Updated: 06/17/2011 - Try some of these mouth-watering recipes from Chef Walter! Lots of them take advantage of all the fresh summer produce or offer something light to eat after a hot summer day.
Updated: 05/26/2009 - Grab a book this summer and head to the beach! What better way to soak up some rays then in the pages of a good read!
Updated: 06/17/2011 - Activities the whole family can enjoy!
Updated: 06/17/2011 - Indoors or outdoors, young and old, crafts are a sure way to keep you busy and entertained for the summer!
Updated: 03/02/2009 - Stay in the game and lose weight in 2009!
Updated: 03/11/2010 - A few springtime craft ideas for the whole family to enjoy!
Updated: 03/02/2011 - Spring getaways for the whole family, just for two, or on a budget.
Updated: 03/02/2011 - Try these light and yummy springtime recipes.
Updated: 03/02/2011 - Spring activities the whole family can enjoy.
Updated: 06/17/2011 - The spring/summer season is the time of year that many begin their battle with seasonal allergies. As flowers and trees begin to blossom, so do their counterparts, like pollen, ragweed, and mold.
Updated: 03/01/2011 - While the skies are clearing up, and the sun is peeking through the clouds a little more, the dust and piles still linger in your home. It's time for that annual event that brings dread to most. But it doesn't have to be an event you hate! With a little help, and a few tips from the experts, spring cleaning can be a piece of cake!
Updated: 10/14/2014 - The Life of Denzel Washington.
Updated: 10/14/2014 - Halle Maria Berry was the first African-American actress to win the Oscar for her lead role in the dark drama, Monster's Ball.


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Women, men, college students and children in more than 170 countries and regions will celebrate World Day of Prayer on Friday, March 6.
The women of Papua, New Guinea have written the World Day of Prayer 2009 service around the theme, "In Christ, there are many members, yet one body."
They welcome all to Papua, New Guinea, a land of many languages, cultures, traditions and beliefs. Though many of its communities experience isolation due to rugged terrain, there is diversity.
The women say, "By God's grace, we are able to be united."
Along with zillions of other people, my daughter, Alison, writes a blog.
As The Neurotic Housewife, Alison writes about her life as a stay-at-home mom, and I've thoroughly enjoyed getting to know this side of her in a horrifying sort of way.
It's like looking into a mirror.
Oscar Wilde once said, "All women become like their mothers. That is their tragedy."
As my girls grew up, I often taunted them with that. Oh yeah? You think I'm a fruitcake? Just wait until you get older and you find yourself doing the exact same things.
Three local congregations will observe the beginning of the Lenten season, the 40 days preceding Easter, with an Ash Wednesday service at 7 p.m. on Feb. 25 at Bethel First Presbyterian Church.
The church is located at 502 E. Main St. in Campbellsville.
St. Thomas Episcopal Church, Fannie Chapel Christian Methodist Episcopal Church, and the host congregation will join in the traditional Ash Wednesday liturgy and imposition of ashes.
Campbellsville University will host The Elizabethtown Area Sacred Community Choir on Friday, Feb. 27, at 7:30 p.m. in the Ransdell Chapel.
The concert is part of CU's Baptist Heritage Series that culminates in the "Celebrating 400 Years of Baptist Heritage" event April 2 at the Louisville campus. The Robertson Worship Endowment is also a sponsor of the concert.
The performance, titled "Honoring Baptists," is free and open to the public.
I promised Gator that I would write about him. His real name is Mike, and he lives in the woods in a camp with some other people.
I only met him briefly, which is par for the course for reporters. We get to know people long enough to get what we need for a story, but often not long enough to care.
I'm talking about myself here, and the truth is I'm not proud of it. But I'm telling you this because God's been chipping away at my uncaring, although he's got a long way to go.
Pleasant Union Baptist Church will host a black history program on Sunday, Feb. 22 at 3 p.m.
Teresa Haskins Smith of Louisville will be the guest speaker. Smith is the daughter of Willie Haskins and the late JoAnn Haskins.
Music will be provided by Campbellsville University's African American Leadership League.
The first thing I asked Sean Gebhard was, "Do people think you're crazy?"
Sean runs the Upper Room Café in Mount Dora, a cute little town about 40 miles east of where I live in central Florida.
I had heard about his "Holy Spirit-filled café" upstairs in the historic Renaissance Building, and the last time we were in Mount Dora I stopped in to see it for myself.
Campbellsville University will host David Garrard, an illusionist who is minister to children at St. Matthews Baptist Church in Louisville, for chapel Wednesday, Feb. 25 at 10 a.m. in Ransdell Chapel. The public is invited to attend this event.
Garrard is in his 32nd year as minister to children at St. Matthews Baptist Church. He has served as an illusionist for 40 years, after having become interested in the business when he was 12 years old.
An organizational meeting for the local World Day of Prayer observance will take place at 2 p.m. Sunday at Our Lady of Perpetual Help Catholic Church.
Those interested in participating in this ecumenical prayer service are invited to attend.
World Day of Prayer will take place at 7 p.m. on Friday, March 6 at OLPH Catholic Church.
For more information, call 465-3966.
Greensburg United Methodist Church will continue taking orders for Angel Food Ministries through February.
This month, the regular menu, which costs $30, consists of 1 1/2 pounds of sirloin strip steaks, 2 pounds chicken breasts, 1 pound boneless pork chops, 2 pounds chicken nuggets, 28 ounces Salisbury steak, 12 ounces sliced bacon, 1 pound hot dogs, 1 pound stir fry, 1 pound carrots, 10 ounces peanut butter, 32 ounces shelf stable milk, 35 ounces French fries, 7 ounces macaroni and cheese, 1 pound rice, 1 pound bean soup mix, dozen eggs and a dessert item.
Copyright © 2016
The Central Kentucky News-Journal is your source for local news, sports, events, and information in Campbellsville, KY and the surrounding area.


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A Hannibal man with a felony warrant was taken into custody Wednesday night without incident in Ralls County.
According to Sheriff Gerry Dinwiddie, at approximately 7:30 p.m. Wednesday he and Chief Deputy Haught observed a vehicle behind a closed business along U.S. 61, just south of Hannibal. While investigating, a person wanted on a felony warrant for $100,000 cash bond was identified as the driver of the vehicle. Christopher Jared Parsons of Hannibal was arrested at the scene.
The Hannibal Police Department's K-9 unit was called to the scene. During a search of the vehicle, narcotics were allegedly discovered, according to Dinwiddie.
In addition to the Hannibal Police Department, the Ralls County Sheriff's Department was assisted by the Missouri Highway Patrol.
Location, ST | website.com


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Hi everyone!
Let me just say, I bought a PS3 solely for 2-3 games I have missed during this gaming generation. And when I heard about this function about using it as a Media Hub, I got incredibly enthusiastic. Having owned a 360 which had so many limitations, made me go crazy about this function.
However, it took A LOT of time to fix. At first, nothing would stream correctly. I tried tweaking the PMS server, I tried converting file formats... Eventually it stopped working all together. I followed loads of help threads, youtube tutorials, etc..
I even bought a cable to connect the PS3 by wire to the router, instead of WLAN. I even set up static adresses for my computer and PS3 (I guess this one should have been done sooner or later anyways)
Now, it works.. Kind of.. I can't stream MKV files.
At first, by WLAN, the MKV file wasn't streaming pretty good at all.. Then when I (somehow) got that fixed, it started jumping at random places in the film. Like, from 1:30, it suddenly got to 4:25. As far as I can see, it wasn't at the same amount of times inbetween, only the same places in every film I was testing it with.
After I now bought a wired cable, reset the PMSconfig to its original factory settings (Without thumbnails) it worked a lot better. Except now, it jumps a bit later, and at smaller distances.
What can I do? Because it feels like I've tried everything..
I did manage to copy one MKV file from my PC to my PS3, over wifi (Before I did all the tweaks) and I would have no problem about doing that in the long run either. But it seems like when I copy the files, the copying instance crashes after a while. No matter what. Gonna try it with a wire tonight, but it would be kinda sweet to stream my films as well!
Currently, my peak bitrate is 30 mb/s (which is more than double what it was over Wifi) and transcoding buffer status is at 100 MB roughly. (I'm guessing it goes up and down)
ANY help is appreciated! And I am fairly average with computers, but I won't understand code stuff without a directive on where to paste them
Also, real sorry if this isn't allowed for posting, or posted in the wrong forum or anything like that.. Just thought that googling a bunch of threads wouldn't help me any more than just asking about my problems directly.


text: I am an old grumpy guy and have really enjoyed the writing and stories of GRRM every since I read Fevre Dream so long ago I can't remember when it was exactly. I found Game of Throne about 4 or 5 years ago and books 1-4 were already written and I was able to pour through them. I loved them! It is an amazing story with a lot of depth and different points of view. This quickly became my favorite series I have ever read, but not to the point that I dote on the the guys every written word (unlike some of the more doe-eyed lovers of Rothfuss' every word for example). Here is what has begun to drive me crazy as I read ADWD (and admittedly enjoyed it a great deal!). In another thread someone mentioned the phrase "Words are Wind" as being used a bit too much in ADWD. I remember thinking... it's a good phrase... I like it. I began to think of it as I listened to members of Congress talk about the national debt. Then I began to read ADWD. After a long and frustrating wait, I have really enjoyed the book but since someone planted that seed I am stuck hating Martin's overuse (IMO) of these things.. 1) "Words are wind" 2) "Little and less" 3) "Much and more" 4) "useless as nipples on a breastplate" My problem is the number of times these are used, but also the wide variety of people... of different parts of that world... of different backgrounds ....different dialects ... high and low born alike.... who use these same phrases. Not saying this should bother anyone else, and I liked the book, just saying these were used too much and that I may not have even noticed if one of you jackwagons here hadn't planted the seed in my mind!


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Police in Asheville, North Carolina have arrested Craig Baldwin, the Aiken man accused of murdering his elderly mother, Dale Baldwin, at their York Street home nearly three weeks ago. Baldwin is booked as inmate number 124907 at the Buncombe County Detention Center, awaiting an extradition hearing.
The Aiken Department of Public Safety issued an arrest warrant Wednesday and a nationwide alert went out to media outlets in and around Lexington, Kentucky, where Baldwin had last been spotted at his daughter's wedding on June 24.
Thursday, at 8:45, in a hotel room in Asheville, North Carolina, U.S. Marshals arrested Baldwin. He was taken into custody without incident by deputies and the Asheville Police Department's SWAT team.
Baldwin was found at the Rock Haven Terrace Motel in Asheville, when a captain with the sheriff's department spotted his car.
According to Sgt. David Turno of Aiken Public Safety, Baldwin will be returned to Aiken, where he will likely stand trial for the murder of his mother, 83-year-old Dale Baldwin.
Baldwin is accused of killing her, wrapping her in a sheet, and leaving her dead body behind bushes in the front yard.
A case that has rattled neighbors for weeks is now one step closer to being solved.
Craig Baldwin was booked into the Buncombe County Detention Center. He is awaiting extradition proceedings.
Baldwin has an extensive criminal history.
His record includes DUI, resisting arrest, disorderly conduct, public intoxication, theft, failure to appear in court, and violating a protective order.


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Clue wrote:Better question, what if a storm hits an area with 3 pools running simultaneously and play is suspended at only 2 of the 3 pools (assuming all pools are same division)......fyi, this happened.
Clue wrote:Does anyone have a picture of captian obvious?
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The first job I had in San Francisco was at a gluten-free wholesale bakery where work days consisted of mixing, baking, and packaging hundreds of really good fudgy brownies. My favorite task was cutting up "brownie favors," irregular pieces that got weighed into bakery bags. It was way too easy to
One year ago:
(Gluten-Free) Über Chocolate Cookies
Two years ago:
White Bean, Kale and Farro Soup with Parsley Pesto
Three years ago:
Breakfast Bars with Tart Cherries, Chocolate and Pecans
Banana Brown Sugar Pecan Scones
Makes one 8 or 9″ cake, 12 small but rich servings
scant 1/2 cup (2 ounces) natural or blanched whole almonds, or 1/2 cup (2 ounces) almond meal
2 tablespoons (3/4 ounce) sweet rice flour (such as Mochiko)
6 ounces bittersweet chocolate with 70-72% cacao mass, roughly chopped (1 1/4 cups)
1/2 cup (3 1/4 ounces) flavorful olive oil, plus extra for serving
1/8 teaspoon salt
4 large eggs, separated, at room temperature
3/4 cup (6 ounces) sugar, divided use
1/4 teaspoon cream of tartar
flaky salt for serving
unsweetened whipped cream, for serving
Position a rack in the center of the oven and preheat to 325º. Grease an 8 or 9″ round springform pan with a bit of olive oil.
If using whole almonds, grind them with the flour in a food processor or clean coffee grinder until powdery. Sift out any chunks and set aside.
Place the chocolate, oil and salt in a large, metal bowl. Place the bowl in a skillet filled with 2″ of barely simmering water, and stir frequently until the chocolate is melted. Remove the bowl from the skillet and whisk in 1/2 cup of the sugar, and the almond mixture (or the almond meal and flour) until combined. Whisk in the egg yolks. If the mixture gets cold, it may start to "seize" or look grainy. In this case, place the bowl back into the warm water and stir until it loosens up again.
Place the egg whites and cream of tartar in the bowl of a stand mixer fitted with the whisk attachment. Whip on medium-high speed until foamy, then gradually pour in the remaining 1/4 cup of sugar, whipping the whites until they hold soft peaks (i.e., when you pull the whisk out and hold it upside down, the peaks of white flop over).
Without delay, use a rubber spatula to stir 1/3 of the whipped whites into the chocolate mixture, then gently fold in the remaining whites until the batter is just combined and no streaks remain.
Immediately scrape the batter into the prepared pan, and smooth the top. Bake the cake until a toothpick inserted in the center comes out with moist crumbs, 40-45 minutes. Let the cake cool completely, then remove the sides of the pan and sprinkle with a bit of flaky salt. Use a large chef's knife wiped clean after each cut to slice the cake into thin wedges.
Serve each slice with a dollop of cream and drizzle of super good olive oil. The cake will keep, covered and at room temperature, for up to three days.


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Though impending federal legislation will soon require all 20-plus-unit chains to post calorie info on menus, many were shocked that McDonald's was one of the first to proactively do so nationwide.
McDonald's, however, sees its move more as a sign of the times, realizing that consumers are more concerned than ever with what and how much they're eating.
"We know our customers want to know more about our food and beverages and our menu," says Molly McKenna Jandrain, director of public relations for McDonald's USA.
She points out that, while McDonald's has been providing nutritional information access to its guests for more than 30 years, this step take it to a whole new level.
"What's different with this is it allows people to see the calories at the point of purchase when they're making their decisions," she says. "We've always been committed to providing the information, and this is just the latest step."
And though McDonald's is excited about and proud of its decision to launch the calorie-labeled menuboards in stores beginning this week, Jandrain says it was an operational challenge the brand had to long prepare for.
"We obviously can't turn things overnight, so we've been planning this for quite a long time in terms of deploying this in our restaurants, working with our suppliers to get the menuboards ready, analyzing and continuing to stay current on all of the nutrition information," she says. "We planned for it and took all the right steps so we could put it in our restaurants in a unified and timely manner."
So far, Jandrain says customers have appreciated the brand's efforts to provide them with more nutritional knowledge. And many guests are shocked—in a good way—over the number of calories in some of their favorite items, she adds.
"Sometimes people expect things might be higher than they really are, and so it's been really positive in terms of people being pleasantly surprised that we have some great choices … that really can fit into their diet," she says.
And McDonald's didn't just stop at posting calorie counts; it's also testing a number of more nutritious and wholesome items to add to its menu. Jandrain says it is continuing to look at seasonal vegetable and fruit options—playing off the success it had recently with blueberries—and may even add a blueberry-pomegranate smoothie to the lineup.
For the breakfast daypart, it's playing with egg-white sandwich options, which Jandrain says are similar to the Egg McMuffin, but made with 100 percent grilled egg whites and white Cheddar cheese. The sandwich rings in around 250 calories and comes on an English muffin with 8 grams of whole grains.
In Chicago, it's also testing McWraps in a number of varieties, including Chicken & Ranch, Sweet Chili Chicken, and Chicken & Bacon. These better-for-you products include produce like spring mix lettuce, tomatoes, and cucumbers.
But whether these items stick around is up to the customers. "With any test, to be successful, our customers have to like them and be purchasing them," Jandrain says, noting that customer feedback has been positive so far.
McDonald's is also trying to get its employees involved in the healthy mission by providing a voluntary nutrition e-learning program for its almost 750,000 crew members.
Jandrain says the company wants its staff to be proud of the food they're serving, as well as be educated on the nutritional information of the items so they can answer any customer questions.
"We feel that it's important that, just as we're trying to educate our customers on the calorie information and the food and the choices that are best for them, we need to do the same thing with our crew," she says. "We want to make sure they're equipped with the right information and really proud to continue serving our food and beverages."
By Mary Avant
Recommended Stories
Thomas replied on Permalink
I think this is an awesome idea.


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- Jul 9:
- Roadshow: Bay Bridge delay gets mixed reviews
- Jul 8:
- Bay Bridge's steel bolt failures reveal inadequate metallurgy expertise, experts say
- Bay Bridge: Opening of new span to be delayed for weeks or months
- Jun 12:
- Bay Bridge: Open new span with or without bolt repairs, experts say
- Jun 2:
- Daniel Borenstein: Bay Bridge officials don't walk the transparency talk
- May 29:
- Will the new Bay Bridge open on time?
- May 28:
- Bay Bridge suspense continues
- Contra Costa Times editorial: Bay Bridge executives failing to produce basic written reports
- May 24:
- Roadshow: I-580's extra lanes leave no median for BART to Livermore
- May 23:
- Bay Bridge bolt maker says report 'exonerates' it from blame
- May 22:
- Details emerge on who picked steel for Bay Bridge that later broke
- May 21:
- Gov. Jerry Brown: Bay Bridge 'not going to open unless it's ready'
- May 8:
- Live coverage: Bay Bridge bolt fix to cost $ 5 million to $10 million
- May 7:
- Bay Bridge: Caltrans to reveal how it will fix bolt problems on span
- California Gov. Jerry Brown breaks silence on cracked Bay Bridge bolts
- Bay Bridge technicians 'listen' for cracking in the steel anchor rods
OAKLAND -- A simple welding mistake led to small bolts that sheared on the new Bay Bridge's bike and pedestrian path railing last year and the bolts were subsequently replaced in early 2013, bridge spokesman Andrew Gordon said Wednesday.
The undetermined number of broken fasteners were discovered where the railing is bolted onto the deck on one side of a series of expansion joints, or small spaces that allow the structure to expand and contract with the temperature.
The contractor mistakenly welded decorative caps directly onto deck plates rather than the tops of the bolts, which are threaded through oval grooves that allow the path to move but keep the railing in place, Gordon said. As the structure heated and cooled, the bolts' movements were restricted and sheared under the unintended load.
Inspectors discovered the glitch last year and the contractor subsequently replaced all the bolts. The decorative caps were eliminated, Gordon said.
Unlike the high-strength steel anchor rods elsewhere on the bridge that snapped in early March due to hydrogen embrittlement, the steel used to make the small bolts that secure the railing to the pathway is not in question, Gordon.
"This was not a steel problem," Gordon said of the pathway repairs. "It was a minor welding mistake and it has been corrected."
Contact Lisa Vorderbrueggen at 925-945-4773, firstname.lastname@example.com, politicswithlisav.blogspot.com or Twitter.com/lvorderbrueggen.