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SANTA CLARA -- Alex Smith doesn't think his sprained middle finger will be an issue when the 49ers host the New York Giants on Sunday.
"It's doing all right. It'll be fine," Smith said Wednesday. "I might tape it for support."
Wearing no splint or bandage, Smith fully participated in Wednesday's practice and showed no ill effects while throwing. He hurt his finger on his right, throwing hand after attempting his final pass in Sunday's 45-3 rout of the Buffalo Bills.
Coach Jim Harbaugh said his fears were alleviated when he saw Smith throw earlier this week, noting: "He says he's doing good, that it's not a big deal."
Meeting President Barack Obama, however, was a big deal Monday night for Smith, who attended a San Francisco fundraiser along with tight end Vernon Davis.
"Very cool. Huge honor," Smith said of fulfilling his childhood dream to meet a president. "He talked ball the whole time. He was down to earth. He knew what was going on with us and knew we'll be playing the Bears (on Nov. 19)."
Smith's sister Mackenzie works for the chair of the Democratic National Committee, Debbie Wasserman Schultz. While Smith and his wife, Elizabeth, posed for pictures with Obama, Davis brought along his 5-year-old son, Jianni.
Davis met Obama earlier this year and even attended the White House correspondents' dinner in April. "I just support him and I like him," Davis said.
In the wake of the 49ers' franchise-record 621 yards against the Bills, Harbaugh said his players "outperformed" his expectations.
Coughlin spoke highly about all facets of the 49ers and says the Giants' first objective is to stop the 49ers' league-leading rushing attack: "Frank Gore is an outstanding player, they have an excellent offensive line, and they're doing the things they want to do: They run it, and they run it and they run it."
For more on the 49ers, see Cam Inman's Hot Read blog at blogs.mercurynews.com/49ers. Follow him on Twitter at twitter.com/CamInman.


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SANTA CLARA -- Dashon Goldson drew his fifth unnecessary-roughness penalty of the season on Saturday night, and the 49ers' hard-hitting safety isn't disputing that it was warranted.
"It was a good call by the ref," Goldson said. "If it was helmet-to-helmet, good call. But it wasn't late."
The 49ers led 21-14 in the second quarter when Goldson drew his penalty while tackling DuJuan Harris at the end of a 3-yard run to the 49ers' 46-yard line. Three snaps later, Aaron Rodgers threw a game-tying touchdown.
The league did not immediately respond to an inquiry on whether Goldson will be fined for his hit.
A month ago, Goldson got fined $21,000 by the league for a crushing hit against the New England Patriots' Aaron Hernandez in the 49ers' Dec. 16 win. Goldson said then that he also had accrued $70,000 in fines for uniform violations.
"I just play football, at the end of the day," Goldson said. "I don't try to hurt anybody."
Goldson also drew two unsportsmanlike-conduct penalties during the regular season. He earned Associated Press All-Pro First Team honors for the first time this season, and he was selected to his second straight Pro Bowl. He was the 49ers' franchise-tagged player last offseason and the team can not sign him to a new contract until after the season.

subset: commoncrawl


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— Delaware Valley Arts Alliance and the Callicoon Theater present first-time director Dustin Hoffman's, Quartet starting Friday, April 5.
At a home for retired musicians, the annual concert to celebrate Verdi's birthday is disrupted by the arrival of Jean, an eternal diva and the former wife of one of the residents.
Starring Maggie Smith, Tom Courtenay, Billy Connolly and Pauline Collins, Quartet is rated PG-13 and will screen Friday, April 5 – Thursday, April 11, nightly at 7:30 p.m., with matinees at 2 p.m. on Saturday and Sunday at the Callicoon Theater, 30 Upper Main Street, Callicoon.
Co-sponsored by Callicoon Theater and Delaware Valley Arts Alliance (DVAA), CineArt brings independent and foreign films to Sullivan County audiences.
A percentage of admissions and $1 per person helps to support DVAA programs in the visual, performing, literary and media arts. Admission is $10 ($8 on Monday night and matinees). Children under 12 are always $7.
For more information call the Callicoon Theater at 887-4460.
Location, ST | website.com


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The following is an excerpt from our 2013 Annual Report: A Recipe for Success.
"Creating private inpatient rooms at Gifford will further enhance patient satisfaction and overall experience in the hospital. We strive very hard to deliver great nursing care, high level hospitalist and ancillary services to the community. Very soon we will have expanded facilities to offer private rooms to our patients, which will allow for less disruption and a greater opportunity to heal. I am extraordinarily impressed and proud of the care we deliver at Gifford, and fortunate to have the opportunity to be part of this great place."
~ Dr. Martin Johns, Hospital Division Medical Director
Here is a complete list of all those who worked at Gifford in 2013:
Bernd Dotzauer, MD
Anthony Fazzone, MD
Dennis Henzig, MD
Jon-Richard Knoff, MD
Nazek Shabayek, MDMadeline
Waid, MD
Andrea Williams, MD
Bruce Andrus, MD
Tim Beaver, MD
Chiropractic Sports Medicine
Hank Glass, DC
Andrea Kannas, DC
Emergency Medicine
Gretchen Andrews, MD
Jared Blum, MD
Steven Fisher, MD
Sarah Johansen, MD
Martin Johns, MD
Marc Keller, MD
Thomas Leeson, DO
Wayne Misselbeck, MD
Todd Morrell, MD
Duane Natvig, MD
Paul Newton, MD
Saul Nurok, MD
Kevin Rodgers, MD
Scott Rodi, MD
Brian Sargent, DO
A. Nicole Thran, MD
Joshua White, MD
Family Medicine
Kenneth Borie, DO
Terry Cantlin, DO
Marcus Coxon, MD
Jonna Goulding, MD
Barbara Lazar, MD
Brian Sargent, DO
Mark Seymour, DO
Sheri Brown, APRN
Tammy Gerdes, PA-C
Emily LeVan, APRN
Tara Meyer, APRN
Megan O'Brien, APRN
Rebecca Savidge, PA-C
Starr Strong, PA-C
General Surgery
Ovleto Ciccarelli, MD
Maury Smith, MD
Laurie Spaulding, MD
Nikki Gewirz, PA-C
Hospitalist Medicine
William "Sandy" Craig, MD
Martin Johns, MD
Joshua Plavin, MD, MPH
Kevin Rodgers, MD
Wendell Smith, MD
Sheri Brown, APRN
Sue Burgos, PA-C
Amanda Flyckt, APRN
Megan O'Brien, APRN
Fred Staples, PA-C
Internal Medicine
Milton Fowler, MD
Mark Jewett, MD
Cristine Maloney, MD
Mary LaBrecque, APRN
Internal Medicine and Infectious Disease
James Currie, MD
Internal Medicine and Pediatrics
David Pattison, MD, MPH
Joshua Plavin, MD, MPH
Mental Health
Cory Gould, LPMA
Robert Vaillancourt, LPMA
Donna Butler, CNM
Ellen McAndrew, CNM
Laureli Morrow, CNM
Kathryn Saunders, CNM
Meghan Sperry, CNM
Tanya Waters, CNM
Naturopathic Medicine
Christopher Hollis, ND
Erica Koch, ND
Robin Schwartz, MD
G. Brent Burgee, MD
Anne Galante, MD
Dina Levin, MD
Ellamarie Russo-DeMara, DO
John Valentine, MD
Christopher Soares, MD
Jesse Hahn, MD
Stephanie Landvater, MD
Jayne Collins, PA-C
Bradford Salzmann, PA-C
Cathy Palmer, MD
Brian Travis, MD
Louis DiNicola, MD
Elizabeth Jewett, MD
Joseph Pelletier, MD
Robert Smith, DO
Pamela Udomprasert, MD
Podiatry and Sports Medicine
Nicolas Benoit, DPM
Kevin McNamara, DPM
Robert Rinaldi, DPM
Paul Smith, DPM
Pulmonary Medicine
Marda Donner, MD
Yvette Bailey, MD
John McIntyre, MD
Scott Smith, MD
Sports Medicine
Peter Loescher, MD
Andrea LaRosa, APRN
Michael Curtis, MD
Richard Graham, MD
Nancy Blessing, PA-C
Vascular Studies
Andrew Stanley, MD
Georg Steinthorsson, MD


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'American Horror Story,' Season 2, Episode 6, 'The Origins of Monstrosity': TV Recap
This week's episode is called "The Origins of Monstrosity." Some of the human monsters' motivations are revealed (nothing on the aliens and their unhappy childhoods, yet).
The framing device returns, as a 911 call summons police to the ruins of Briarcliff. Police find hanging bodies wearing Bloodyface masks.
A little girl, who resembles PattyMcCormack as Rhoda in "The Bad Seed," with long braids, is brought by her mother to Briarcliff. Mrs. Reynolds suspects that her daughter Jenny killed her friend Josie. Jude tells her that Briarcliff lacks a children's ward, but the mother abandons the girl when Jude is not looking.
Thredson's mommy issues are next. Lana wakes up in her own room: but it's not, just a replica Thredson built in the white-tiled dungeon. He's made her tomato soup and a croquet monsieur, which is what he supposes her mother made for her after school. His own mommy never made it for him, because she abandoned him to a strict orphanage when she was Lana's age. Psycho or not, it has to be said that Quinto is hot in the Marlon Brando undershirt. When she praises his act of kindness for the sandwich, he laughs and cries: "You're the one!" Aw, he's a Lost Boy, who wants a Mother. He tells her how in medical school he realized he craved "skin to skin contact." But a cadaver smelled of formaldehyde, and just didn't do it for him, so we see his first woman-flaying.
The Monsignor, we learn, got sucked into the evil that is Gruper by wanting to believe the ends justify the means, and by wanting to be in Rome. Summoned to the hospital to give last rites to a monstrous woman, he recognizes her as Shelley, and he (and we) flashback to 1962 to his first meeting with Arden. The church had bought Briarcliff and Arden was about to be kicked out, but he told the Monsignor about how his experiments on live subjects would be for the greater good, and could even lead to Rome. A successful tempt, for a man who wasn't the devil. In the present, the Monsignor mercy-strangles Shelley with his rosary beads, and confronts Arden.
Arden proudly shows the Monsignor a mutilated man, a new human being who will be able to survive nuclear attacks. Although the Monsignor is horrified, Arden reminds him they are in this together, and have a common enemy.
Meanwhile, Bad Seed Jenny bonds with Sister Mary Eunice, who is chopping up vegetables. Mary Eunice casually admits that she is the devil, that there is no God. She tells Jenny she is special for following her impulses. Flashback to young Mary Eunice (she too kept her own name) at a pool party, tricked into dropping her robe, naked, when every other girl wore a bathing suit. She's humiliated.
The Monsignor tells Jude she's being transferred to a home for wayward girls in Pittsburgh. Jude yells at him that this is about Dr. Arden, and she's right of course. Jude earlier received a call from Goodman the Nazi hunter informing her that Arden was really was an S.S. officer, and a doctor at Auschwitz, who received a Red Cross pass to travel as Arthur Arden. Goodman needs a fingerprint to match the document.
Mary Eunice visits Jude, ostensibly to tell her about Mrs. Reynolds returning to pick up Jenny, but really to pry, and steal Jude's red slip. While Jude is persuading Arden to drink a toast, Mary Eunice dances, hilariously, to Lesley Gore singing "You don't own me." She pretends to be Jude when Goodman calls. Uh oh. Soon Mary Eunice visits Goodman in his motel room. By the time Jude gets there, with a fingerprinted glass, Goodman is twitchily dying. Before he expires, he tells her it was "the nun."
Lana cuts a link on her chain while Thredson answers Kit's phone call from the police. When Kit wises up to Thredson's betrayal, Thredson goes to "Mommy" for comfort. He is outraged when he sees how Lana was about to try to abandon him. He prepares to flay her, wearing the Bloodyface mask, but, with a flash of genius, she forgives him, because a mother's love is unconditional. He weeps and pulls off the mask, then nurses on her breast. She's not into it.
Little Jenny lies to the police that a man with a brown jacket stabbed her brother and sister, and then her mother. We see her mother's been stabbed in the back with the kitchen knife from Briarcliff.
Mary Eunice tells Arden he was handsome, looking at his Red Cross Pass. He hates being called Hans, and wonders why she's protecting him. He knows she's not in love with him. She just tells him to trust him with his whole soul.
The hanging bodies in Briarcliff present are teenagers. Police find Leo's body, and answer a call his severed hand is holding: it's Bloodyface, who tells them he only killed the impostors. A detective says that Leo's sister called to say he was on his honeymoon. In that case, where's the bride?
On a slab about to be tortured.
Who is Bloodyface now?


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ATLANTA (AP) -- Governor Perdue asked the state's schools to take two "early snow days" and cancel classes Monday and Tuesday to help conserve gasoline as Hurricane Rita threatens the nation's fuel supply line.
If all of Georgia's schools close, the governor estimated about 250-thousand gallons of diesel fuel would be saved each day by keeping buses off the road.
The governor also said an undetermined amount of regular gasoline also would be saved by allowing teachers, other school staff members and some parents to stay home those days. Electricity also would be conserved by keeping the schools closed.
*The following public schools have confirmed they will be closed: Lincoln County, Columbia County, Glascock County, Jenkins County, Burke County, Washington County, Jefferson County, Emanuel County, Warren County, McDuffie County, Richmond County, Screven County, Taliaferro County, Warren County and Wilkes County.
*Select private schools will also be closed Monday and Tuesday:
-Hope Christian School
-Burkehaven Christian School in Waynesboro will both be closed.
-Montessori School of Augusta for state-funded students, school is closed Monday and Tuesday, private-funded students still have school.
-Southside Outreach Community Program
-Columbia County Christian Academy
-Hillcrest Baptist Church School-First Baptist Church of Evans Mother's Day Out and Preschool
-Southgate Christian
*Augusta State University will be open on Monday, September 26, and Tuesday, September 27.
*Augusta Tech: Monday and Tuesday, closed for students, instructional
support, and instructors; Monday and Tuesday, open for administrators and staff.
*Due to the Governor's request for voluntary snow days, the Georgia Department of Education makes the following announcements:
- All GaDOE sponsored training and events for Monday and Tuesday have been postponed. This includes Georgia Performance Standards training sessions.
- The administration of the Georgia High School Writing Test will be postponed until Thursday and Friday.
- The second leg of the Georgia Partnership for Excellence in Education's bus trip has been postponed.
Stay tuned to News 12 and wrdw.com for updates.


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NEW: For a prettier blog interface, see the Wordpress version!
|Write the CS21A midterms {{Tasks:332}}
|Download source for wayv {{Tasks:341}}
|Deal with write-file-functions {{Tasks:328}} (E-Mail from Oliver)
|Reply to Doc Oly and try to convince him that playing chess with a girl isn't all that bad ;) {{Tasks:330}} (E-Mail from RAUL A. JAVIER M. D.)
5. Wayv and research potential
strokes-mode? Hmmm. Ooooh, joy, it's right there. I love Emacs!
4. Geek power
Quick thinking and an almost conspiratorial comment may have helped avert an ugly mood; if not that, at least force of will and appreciation of pressure. There will be time for recriminations later, perhaps. Were it up to me there would be no time for recriminations at all, there being so many other ways to gently shape someone's behavior. (Like a bonsai is grown not by slashing off large chunks but rather by persuading little branches to grow certain ways...)
And - oh yes - geek power. One of my father's assistants had spent an afternoon working on the computer as it refused to recognize one of the digital backs we use. Quick, short, discouraging beeps and an unhelpful dialog box were all he got for his efforts. With some Googling and an almost unconscious sense of what might be important, I got the whole thing up and running. Wheeeee. =)
3. Dominique's cousin's mailing address
E-Mail from Dominique Cimafranca
2. Knitting so far
1. Woohoo! Emacspeak back up!
emacspeak-planner.el in ../emacs/emacs-wiki has preliminary support. emacspeak doesn't seem to like invisible text in emacs-wiki. Fix one of these days.
I'd love to hear about any questions, comments, suggestions or links that you might have. Your comments will not be posted on this website immediately, but will be e-mailed to me first. You can use this form to get in touch with me, or e-mail me at email@example.com .


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|Additional Reference
|AVX Wire to Board Poke Home Connector
|Interactive Connector Selector Guide
|Polymer Capacitors - Fast Facts
AVX is a leading worldwide manufacturer and supplier of passive electronic components and interconnect product. The goal of AVX is to provide total customer satisfaction through continuous improvement, cutting edge technological solutions, customized product offerings, and the deepest breadth of capacitors available. Unique product and materials technology, like the award winning OxiCap™, niobium oxide capacitor and the BestCap™ Pulse SuperCapacitor, have helped AVX facilitate superior end product designs for customers. Innovations in low inductance and low ESR capacitors, compliant pin interconnects, as well as circuit protection devices have ensured that AVX products can meet the ever increasing system performance requirements in the market.
Through this site you may search our huge inventory of AVX's passive and interconnect products. The product highlights below capture some of the key new and focus products, but these represent only a small portion of AVX's broad capabilities. Should you need additional assistance, TTI's customer service team is ready to help at 1-877-645-4TTI.


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Welcome to the Silhavy Lab
All cells have subcellular compartments that are bound by lipid bilayers, and this three-dimensional organization is essential for life. If we consider lipid bilayers themselves as compartments, then Gram-negative bacteria, such as Escherichia coli, have four distinct subcellular locations: the cytoplasm, inner membrane (IM), periplasm, and outer membrane (OM). The noncytoplasmic compartments are collectively termed the cell envelope. We wish to understand cellular assembly, in particular, the process of OM biogenesis. The OM is an asymmetric lipid bilayer containing phospholipids in the inner leaflet and lipopolysaccharide (LPS) in the outer leaflet. Membrane spanning outer membrane proteins (OMPs) typically assume a beta-barrel conformation. All OM components are synthesized in the cytoplasm or the IM and therefore, OM biogenesis requires the transport of these molecules across the cell envelope for assembly at their final cellular location. Strikingly, these transport and assembly processes occur in an environment that lacks an obvious energy source such as ATP. We have used a combination of genetics, biochemistry, and bioinformatics to identify the cellular machinery required for the assembly of OMPs and LPS in the OM. Both of these assembly machineries have protein components in every cellular compartment, and this spatial organization suggests the temporal order of component function. Current effort in the lab is directed towards understanding how these machines function in molecular terms, and how the various envelope stress responses maintain cell integrity.


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BARBOURVILLE, Ky. - The Union College softball team fell in two games to Virginia Intermont on Saturday in Appalachian Athletic Conference action at Union Field. The Lady Bulldogs dropped a heartbreaker in game one, 3-2, then lost game two 13-4 in five innings to the visiting Lady Cobras.
With the pair of losses, UC fell to 10-14 overall, 2-6 in the AAC, while VI improved to 21-5, 7-1 in the AAC with the victories.
Game One
In game one, the Lady Bulldogs fell behind VI 2-0 after three innings, but rallied back to tie the game in the fifth after scoring single runs in two straight innings. In the fifth, Danielle Borum had the game-tying hit, an RBI single up the middle that scored Ashley Wojnowski.
The game remained tied at two entering the seventh inning, where VI's Samantha Perry-Shifflet came up clutch, hitting an RBI single with two outs to give the Lady Cobras a one-run lead.
In the bottom of the seventh, UC tried to rally, as Wojnowski led off with an infield single. But, she was stranded at second base, as the game ended after Cameron Campbell had a hard line drive caught in center field for the third out.
Overall, Borum and Campbell each went 2-for-4 to lead the Lady Bulldogs, with Borum picking up an RBI. Both also had doubles in the contest, as well. In the circle, Katie Perkins (7-6) was the hard-luck loser, striking out six, while allowing just two earned runs in the contest. VI's Micalah Sacre (7-1) earned the win, striking out 13 in a complete game victory.
Game One - Turning Point
With the game tied and with runners on first and second with two outs, VI catcher Samantha Perry-Shifflet came to the plate. She came through for the Lady Cobras, knocking home her sister Megan from second base on an RBI, game-winning single into shallow left field.
Game Two
In game two, VI came out and put things away early, exploding for 15 hits in a convincing nine-run victory in five innings.
The Lady Cobras opened a 5-0 lead after two and a half innings, and never looked back. UC did cut the lead to 8-4 entering the fifth after Borum hit a three-run homer in the bottom of the fourth, but VI put UC away in the top of the fifth, scoring five runs to record the big win.
Overall, Borum continued her solid day at the plate in game two, going 2-for-3 with two runs scored, and three-RBI on her home run in the fourth. In the circle, Gianna Schauer (3-7) was the loser for UC, while VI's Rachel Watts (8-0) picked up the victory.
By the Numbers
• Borum completed a very big week at the plate in today's doubleheader. In all, the freshman had eight hits, two home runs, a double, a triple, and nine RBI. Her home run in game two was the third of her season, which is now the team-lead.
• Campbell had three multiple-hits games on the week, and now has seven on the 2013 season.
• Wojnowski scored a run in every game on the week (nine), and has at least one hit in five of the last six games.
Up Next
The Lady Bulldogs host AAC-foe Milligan (Tenn.) in a conference doubleheader at Union Field on Friday. First pitch for game one is scheduled for 2 p.m.


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ARLINGTON, Texas - The Texas A&M - Corpus Christi softball team suffered their fourth consecutive Southland Conference split of the season Saturday, dropping a 2-0 loss to UT Arlington at Allan Saxe Field in Arlington, Texas.
UT Arlington (11-13, 1-1) outhit the Islanders 7-4 and left nine Islanders stranded en route to their first conference win of the season. The Islanders (8-14, 4-4) and Mavericks stayed scoreless through two innings, before UTA scored one in the third and one in the fourth to secure the victory.
Vianca Pesina (1-5) suffered her fifth loss of the season in the circle. The senior tallied one strikeout and didn't give up a walk while facing 25 batters in six innings of work.
Cassie Redman and Hannah Schwarz started things off in the opening frame with walks before the Mavericks defense left the Islanders stranded with one on base.
In the second inning, Valerie Perez tallied the Islanders first hit of the game with a solo shot through first and second with two outs and Callie Collins walked Mickayla Heller to put runners on first and second. The Mavericks were able to get out of the inning though with a groundout.
The Islanders were in scoring position in the third. With Redman on first, Schwarz reached base on a fielder's choice. Schumann then moved Schwarz to second on a rip to left field with one out. Jackson followed suit with a fielder's choice to second to advance Schumann to third. The Mavericks defense once again pulled through to garner the third out of the inning.
The Mavericks tacked on the first run of the game in the bottom of the third when Erica Leflore singled to left center to plate Courtney Zink.
Cassie Carroll started things off for the Islanders in the bottom of the fifth by reaching base before Perez's sacrifice bunt advanced Carroll to second. However, Collins retired the next two Islander batters to pull the Mavericks out of the inning. UT Arlington built a 2-0 lead with another run in the bottom of the fourth.
Courtney Enocksen blasted a shot to left center in the gap of Alejia Cain and Redman. Kaiser then drove her in on a single before Heller pulled the Islanders out of the inning with a throw down to second to get Kaiser out stealing.
The Islanders' bats started to get things going in the fifth. Redman led the inning off with a single and advanced to second on a Schwarz fielder's choice. Schumann followed by reaching base on an error by the second baseman, but the Mavs defense executed leaving two Islanders stranded.
Redman, Schumann, Perez and Cain all tallied one hit apiece for the Islanders.
Collins (6-6) picked up the win for the Mavericks in six innings. She allowed three walks while striking out four.
The Islanders will return home to host Houston Baptist in a non-conference doubleheader on Tuesday, March 27. First pitch is at 2 p.m. at Chapman Field.
For the latest on Islanders Softball, like the team on Facebook (Islanders Softball), follow them on Twitter (@IslandersSB) and visit www.GoIslanders.com.


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J.K. Rowling has announced there will be a new series of Harry Potter spinoff films based on "Fantastic Beasts and Where to Find Them," a fictional textbook used by the students at Hogwarts.
This is where I'm hoping I don't have to explain that Hogwarts isn't real, which might be kind of like telling a Trekkie they should stop crying over Vulcan being destroyed because, after all, Vulcan doesn't really exist (shhh - let them down gently).
According to the Superficial.com, Rowling will write the screenplays herself for Warner Bros. Rowling reportedly wrote on Facebook:
"It all started when Warner Bros. came to me with the suggestion of turning 'Fantastic Beasts and Where to Find Them' into a film. I thought it was a fun idea, but the idea of seeing Newt Scamander, the supposed author of 'Fantastic Beasts', realized by another writer was difficult. Having lived for so long in my fictional universe, I feel very protective of it and I already knew a lot about Newt. As hard-core Harry Potter fans will know, I liked him so much that I even married his grandson, Rolf, to one of my favorite characters from the Harry Potter series, Luna Lovegood.
As I considered Warners' proposal, an idea took shape that I couldn't dislodge. That is how I ended up pitching my own idea for a film to Warner Bros."
Did anyone understand that? I hope so. So what happens to the little kid with glasses?
Rowling also reportedly wrote "Although it will be set in the worldwide community of witches and wizards where I was so happy for seventeen years, 'Fantastic Beasts and Where to Find Them' is neither a prequel nor a sequel to the Harry Potter series, but an extension of the wizarding world. The laws and customs of the hidden magical society will be familiar to anyone who has read the Harry Potter books or seen the films, but Newt's story will start in New York, seventy years before Harry's gets underway."
OK ... so that was the kid with glasses ... right?
No timetable has been set for the films yet, according to reports.
Contact Tony Hicks at Facebook.com/BayAreaNewsGroup.TonyHicks or Twitter.com/insertfoot.


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The ouster of Mt. Diablo school district Superintendent Steven Lawrence will be offered up for public consumption as what is known as a contractual release "without cause."
Loose translation: We'll pay you to leave, so we don't have to pay lawyers to fight you in court.
But you don't need to drill very deep to find a long list of causes. Lawrence was distant and secretive. He made questionable decisions. He never embraced transparency or showed an aptitude for team building.
Trustee Cheryl Hansen, not one to mince words, assessed him this way one year ago: "What I have witnessed from this superintendent is a lack of leadership and a lack of planning, transparency and sensitivity to community, student and employee concerns."
None of his shortcomings ranked as fireable offenses, but the collective effect was to make you wonder whether he was the right guy.
He wanted to make administrative hires without school board approval. He endorsed hiring an elementary school principal who subsequently was learned to have violated federal privacy laws and had a DUI conviction. He met in private with Chevron officials while they were seeking a $68 million bid for a district solar project.
In short, he explored the far reaches of acceptable behavior.
Perhaps the single episode that most brought his qualifications into question was the way he reacted to -- and lobbied against -- Clayton Valley High School's petition for charter status.
Teacher Pat Middendorf, who spearheaded the movement, said the reasons for the move were set in place before Lawrence was hired in February 2010 -- the district had been oblivious to concerns about student misbehavior and academic performance -- but she and her colleagues wanted to alert him of their intentions.
"He said, 'This will make me look bad if you go charter,'" she remembered. "Our reaction was: 'You're kidding! That's what you're worried about.'"
Lawrence subsequently threw every possible hurdle into Clayton Valley's path. He announced that its departure would cost the district $1.6 million. He sent messages to parents and teachers throughout the district explaining the hardships this would mean for other schools. Parents turned against parents, schools against schools. School board meetings turned into shouting sessions.
"I can't imagine that it could have been handled more poorly," Middendorf said. "It's still something that hangs between high schools, and even middle schools, because he told their principals to back him up."
The Mt. Diablo school board rejected Clayton Valley's petition before it won on appeal to the Contra Costa County Office of Education. Lawrence didn't take defeat well. Without approval of his own board -- or notifying the county -- he commissioned a financial analysis of what the charter conversion cost the district. It was the last secretive move of a secretive administration.
Hansen was matter-of-fact in explaining Lawrence's departure. She said that a year ago, when talk of extending his contract came up, she urged postponement until after the November board election.
"A lot of times new boards bring a new philosophy," she said. "We got two new board members with a different perspective. The direction we want is a sense of transparency and communication."
It brings to mind Lawrence's words when he was hired: "I know that when I sit in this chair, everything that's done is my fault."
As much as anything, it's what he didn't do that cost him his job.
Contact Tom Barnidge at firstname.lastname@example.com.


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A SALISBURY school has topped the Government's league tables for GCSEs, English Baccalaureate and A-levels in Wiltshire, according to figures released on Thursday.
South Wilts Grammar School came top in the county for GCSE results, with 99 per cent of pupils achieving five or more A* to C grades including maths and English.
The school was also at the top of the table for the percentage of Key Stage 4 pupils achieving the English Baccalaureate, at 76 per cent, and it also came top for its A-level results, with an average point score of 977.4.
Bishop Wordsworth's School, which came second in the county's list for GCSE results last year, is not included in the this year's tables as its students take iGCSE qualifications instead.
Bishop Wordsworth's, the city's boys' grammar school, came fifth in the county for A-levels with an average point score of 919.8, and The Godolphin School was ninth with 879.2.
Wellington Academy in Ludgershall was among the lowest in the county for GCSE results, with 37 per cent of pupils achieving five or more A* to C including English and maths.
Sarum Academy was also near the bottom of the league, with 50 per cent, while The Stonehenge School was at 57 per cent. Across Wiltshire, more pupils than ever achieved good GCSE and A-level grades.
The performance tables show the number of students achieving five or more A* to C grades at GCSE including English and maths has gone up by 1.7 per cent from 2012 to 2013.
And the number of students in the county achieving any five A* to C grade GCSEs has gone up by 1.1 per cent.
Students have also maintained high levels of achievements in post-16 exam results, with 83.9 per cent achieving two or three A* to E grade A-levels. Laura Mayes, Wiltshire Council's Cabinet member for children services at Wiltshire Council, said: "The number of Wiltshire pupils achieving good grades at GCSE has increased this year and more students than ever are making the right progress from primary to secondary.
"These positive results are not just good news for all the schools involved but for each individual student these results prove an excellent springboard for their future education and careers and I would like to congratulate all these hard working students."
Results based on GCSEs at grades A* to C (of 33 schools ranked in Wiltshire):
South Wilts Grammar School (1)
Leehurst Swan (3)
St Edmund's (8)
St Joseph's (14)
Avon Valley College (15)
Wyvern College (16)
The Trafalgar School (21)
The Stonehenge School (27)
Sarum Academy (29)
The Wellington Academy (33)
Results based on average point score per A-level student (of 28 schools and colleges ranked in Wiltshire):
South Wilts Grammar School (1)
Bishop Wordsworth's Grammar School (4)
The Godolphin School (9)
The Wellington Academy (26)
Avon Valley College (27)
Wiltshire College (28)


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CORPUS CHRISTI – Peter Nagy and Maider Martin have been named the GoIslanders.com Student-Athletes of the Week, presented by Pepsi. Nagy and Martin earned the awards after winning the singles flights in the Marco & Co. Catering Islanders Open, an officially sanctioned Intercollegiate Tennis Association event.
On the men's side, Nagy swept through the bracket, picking up 6-0, 6-0 wins over his two non-Islander opponents. He also took down teammates Guillaume Rauseo and Matt Westmoreland on his run to the title. He earned a hard-fought 6-3, 6-4 win over Westmoreland in the finals to clinch the title.
Martin earned her title in similar fashion, beating three teammates on the way to the title. She earned wins over Islanders Ashley Garza and Sandra Burges before taking a three-set slugfest by a 2-6, 6-4, 10-6 score in the finals over defending champion Stefania Nicolae to win the title.
Next up for Nagy will be play at the Rice Invitational beginning on Sept. 29 in Houston along with other Islanders men's players, while Martin and the women's team will take part in the ITA Texas Regionals on Oct. 20 at the Baylor campus in Waco. The men's team will also participate in the ITA Texas Regionals, with the tournament taking place in Fort Worth on the TCU campus.
Keep up-to-date with GoIslanders.com each week to see who is named the GoIslanders.com Student-Athlete of the week, presented by Pepsi. Also, for the latest information, follow Islanders Athletics on Twitter (@Go_Islanders) and Facebook (Islanders Athletics).
2012-13 GoIslanders.com Student-Athlete of the week, presented by Pepsi Weekly Winners:
9-5-12: Shannon Hullum, Volleyball
9-11-12: Ivy Baresh, Volleyball
9-18-12: Tyger Holt, Volleyball
9-25-12: Peter Nagy, Men's Tennis and Maider Martin, Women's Tennis


text:
100 years ago
Harry Yeunet was given a preliminary hearing and pleaded not guilty to the charge of attacking Agnes Linscott. He pleaded not guilty and awaits a grand jury.
Marietta millinery establishments are holding spring openings and are advertising new, fashionable clothing.
Compiled by Amanda Nicholson, Marietta College Special Collections.


text:
Kids' Jordan Cartoon Tee Shirt
Young Jordan fans can show their love of one of the greatest players of all time in this cozy tee. Made of ultra-soft, 100% cotton, the Kids' Jordan Cartoon Tee Shirt features screen-printing that showcases the great MJ. Perfect when paired with jeans or comfy shorts, this tee is sure to become a go-to in any kid's wardrobe.


text:
Avoiding the Near Occasion of Sin
What Is the Connection Between Hope
and an Anchor?
Now Can My Marriage Be Recognized
by the Church?
Weddings on the Beach?
Does the Church Approve of Scattering a Person's Ashes?
Q: What do you do if a sin keeps reoccurring?
I know that you must
have true sorrow for committing the sin
and that you must make a firm purpose of
amendment not to commit the sin again.
Must a person change the situations or
circumstances that in the past have preceded
that sin? If one does not change the
circumstances that are contributing to a sin,
is the confession of it still a valid one?
Mike, my boyfriend, stops in after we
have been on a date. I live with my parents,
who are asleep by the time we come in. We
haven't had intercourse yet, but we have
moved beyond kissing and are certainly
headed in that direction. Mike says that he
is not trying to sin with me.
Besides going to Confession, what am I
obliged to do under these circumstances?
A: The short answer is that you are
obliged to do what you know is
right and to avoid situations and circumstances
that will make it very difficult
or nearly impossible for you to
accomplish that.
Intercourse between husband and
wife reflects their lifelong commitment
to each other. Couples who are dating
may or may not marry each other. Under
those circumstances, they should
not act as though their level of commitment
to each other is greater than
it truly is. You are rightly concerned
that you are heading where you personally
are not now ready to go.
Without using the word itself, your
question involves the virtue of prudence.
The United States Catholic Catechism
for Adults, published by the
United States Conference of Catholic
Bishops, describes prudence as the cardinal
virtue "by which one knows the
true good in every circumstance and
chooses the right means to reach that
In A Concise Dictionary of Theology (Paulist Press), Gerald O'Collins, S.J.,
and Edward G. Farrugia, S.J., write that
prudence entails "the capacity to translate
general norms and ideals into practice.
Christian prudence is more than a
mere shrewdness that foresees difficulties
and avoids undesirable consequences."
It helps to make "a coherent
whole of one's moral life."
When people act against what they
know to be morally good, they self-destruct
to some extent because they
voluntarily dull their moral instincts. In
doing so, they slightly redefine, always
in their favor, what they consider "no
big deal."
Although this is clearly bothering
you, it apparently does not bother
Mike—at least not as much. If, however,
you always accept his viewpoint
about what conduct is proper,
isn't that a pretty shaky foundation
on which to build a married relationship
that could last half a century
or more?
Can any good come to the two of
you if it requires a lie to oneself from
one of you? Bit by bit, wouldn't that
person be self-destructing, moving
away from making "a coherent whole
of your moral life"? People can express
their love through not doing certain
things, by saying no to themselves and
yes to the person whom they love.
People sin—that's a fact. Confession
enables us to tell the truth to ourselves
and to God—and then make the practical
decisions that will help us live in
a way that reflects our God-given dignity.
The Confessions you describe are
valid. God is merciful and honest: If we
want different results, we must do our
I once taught a high school student
who asked me at the end of class,
"What do love and self-sacrifice have to
do with one another?" Several things
caused me to believe that his was a sincere
request. Before the bell rang, I
managed to reply that, if he looked
very closely, wherever he observed genuine
love he would always find self-sacrifice
as part of it. In our August
2008 issue, Elizabeth Dreyer's article,
"The Holiness of Everyday Life," addressed
the connection between love
and self-sacrifice.
May you and Mike "live the truth
in love" (Ephesians 4:15). Such honesty
will build a strong foundation for your
future relationship with Mike or with
some other man who will recognize
your strong conscience as the gift it is.
Q: Not long ago I received a charm (a
cross, an anchor and a heart) signifying the virtues of faith, hope and charity.
I know that the cross is a symbol of faith
and the heart represents charity. Why is the
anchor a symbol of hope?
A: Christian art has long used an
anchor to symbolize hope because
an anchor symbolizes that ultimately
our trust is not in ourselves but
in God, who alone is steadfast and reliable.
The author of the Letter to the
Hebrews says that, in making a promise
to Abraham, God swore by himself.
"So when God wanted to give the heirs
of his promise an even clearer demonstration
of the immutability of his
purpose, he intervened with an oath,
so that by two immutable things, in
which it was impossible for God to lie,
we who have taken refuge might be
strongly encouraged to hold fast to the
hope that lies before us. This we have
as an anchor of the soul, sure and
firm..." (6:17-19).
Q: When I married a divorced man
over 30 years ago, I knew that
the Catholic Church of which I am a
member would not recognize our marriage.
My husband and I have attended
Mass regularly but have not received Holy
Communion. We raised our children as
My daughter recently saw on the Internet
that my husband's ex-wife has passed
away. I quietly said a prayer for her and told
my husband about it the next day. He and
I are wondering if now we can marry in the
Catholic Church. Any light you can shed on
this will be appreciated.
A: Yes, you should be able to have
your marriage "convalidated"
(regularizing a valid civil marriage as a
sacrament in the Catholic Church) if
there is no other obstacle. Arranged
through your local parish, a convalidation
will require obtaining an official
copy of these civil records: your husband's
first marriage, the divorce
decree, your present marriage and the
death of his ex-wife.
At www.AmericanCatholic.org,
you will find the online version of our
February 2004 article about convalidation.
Once you and your pastor have
prepared for this, the actual celebration
can be as public or as private as
you and your husband wish.
Q: What can I say to my daughter who
says that my granddaughter wants
to be married on the beach rather than
have a church wedding? There is a fee for
the use of the church, but she can well
afford it.
Weddings on beaches and in gardens
are becoming more and more frequent in
our area. When I mentioned to my daughter
the presence of the Blessed Sacrament
in a parish church, she responded that
God is everywhere.
A: Yes, God is everywhere—even
in churches! Although this issue
arises in terms of where the ceremony
will occur, I suspect there is a much
deeper issue. What does this marriage
represent? Is faith in Jesus important to
the bride and groom? Is this marriage
a statement of faith—as well as an expression
of new obligations according
to civil law?
Permission from the local bishop is
needed for a Catholic to marry outside
of a church. This "dispensation from
form" is more readily given if one of
the spouses is not baptized. Having a
wedding in a church can imply something
that is simply not true for this
couple. For couples who are both Christian,
a church building can remind all
who witness the wedding that the faith
community has a stake in the success
of this marriage.
Beaches, gardens, parks, etc., can still
make for wonderful wedding receptions.
Q: I know that cremation is becoming more common, but I am
aghast when family members or friends say that they are going
to have their ashes scattered in rivers, in forests or on hilltops. What
does the Catholic Church teach about this issue?
A: Your question arises often these days. The Catholic Church
teaches that a person's ashes should be given the same respect
that his or her body is given. Burial in the ground or walled
in a columbarium niche shows that type of respect. Scattering to the wind
or over water does not. If you
search "cremation" on this site, you will find my earlier response to this question and
recommended links for further references.
If you have a question for Father Pat, please submit it here.
Include your street address for personal replies enclosing a stamped, self-addressed envelope, please. Some answer material must be
mailed since it is not available in digital form. You can still send questions to: Ask a Franciscan, 28 W. Liberty Street, Cincinnati, OH 45202.


text:
Castleton Cottages
Please find below a selection of personally inspected holiday cottages in Castleton, Derbyshire. If you are looking for self catering cottages to rent in Castleton, Yorkshire, please click here.
Just show me Castleton Cottages
For natural and historical wonders above and below ground,
unwind in one of our Castleton cottages nestling in the High
Peak's breathtaking Hope Valley. The setting is dramatic,
tucked snugly beneath Peveril Castle in the foothills of Mam Tor.
First stop at the Visitor Centre, where you'll find lots of
information, interactive displays and a small museum. Expect
fantastic walking, as well as rock climbing, mountain biking,
hang-gliding, pot-holing and more.
For unforgettable views, trek up to the imposing Norman castle,
protected by English Heritage, or climb the slopes of Mam Tor
crowned with an Iron Age hill fort. Walk the Pennine Way or enjoy
short, circular walks around the valley. If you're travelling
with children or need accessible routes, try the Castleton Geology
Trail or Historic Shopping Trail, with tearooms en-route offering
welcome refreshments.
Spectacular caves close to your Castleton cottage...
Castleton is home to four amazing show caves. The Peak Cavern
and ancient rope works sits in the village centre and boasts the
biggest entrance in Europe. On the slopes down from Mam Tor are
Treak Cliff Cavern, renowned for its Blue John Stone and
extraordinary stalagmites and stalactites, and Blue John Mine, the
deepest of them all and famous for its stone and extensive cave
system. At the foot of Winnats Pass is Speedwell Cavern, where you
can enjoy an exciting boat ride along an underground canal and peer
down a 'bottomless pit'!
Come evening, look forward to relaxing in your Castleton cottage
or treat yourself to a meal out in one of the village's
inviting pubs. Our Peak District
cottages are perfect for families, couples or
individuals, at any time of the year.


text:
New Article on HantavirusJune 26th, 2009
Ever hear of hantavirus? It is extremely deadly, there is no cure, and the most likely place that you'll find it is in homes. Those are pretty good reasons for inspectors to learn about it. Fortunately, it's very rare, and if you know how it is transmitted you will further reduce your chances of being harmed by it. Check out our new article on hantavirus danger in homes to find out more about this virus and how to avoid it.
This blog entry was posted by Rob London.


text:
Mike Judge, the sardonic wise guy who gave the world "Beavis and Butt-head," "Office Space" and "King of the Hill," has some advice for the eccentric billionaires of the high-tech industry: Chill out and get over yourselves.
Judge's latest dose of satirical snark is "Silicon Valley," an HBO comedy series about a group of young computer geeks with big dreams. But while the show mostly focuses on these underdog outsiders, it also takes lots of shots at the superrich CEOs that Judge believes are too full of themselves.
"There's a sense of self-importance that permeates that community," Judge said in a phone chat. "It's not enough that they just make billions of dollars. They also have to proclaim that they're making the world a better place in various ways, and that's kind of funny to me. ... They continually feel the need to shroud their capitalism in altruism."
In "Silicon Valley," which gets a sneak preview Wednesday night at the Fox Theatre in Redwood City and airs beginning Sunday, Judge and collaborator Alec Berg gleefully mock the tech titans. They're depicted as humorless dolts, wealthy enough to hire Kid Rock for their private parties, but too uptight to rock out. They drive goofy cars, wear weird clothes and spout eye-rolling bromides like, "We can only achieve greatness if first we achieve goodness."
Berg, who wrote for "Seinfeld" and "Curb Your Enthusiasm," is convinced there's a "rampant smugness" in the valley that is ripe for skewering.
"It's like the whole Google shuttle thing," he said. "You can gentrify the neighborhood and drive out the middle class, but you get a pass, because, apparently, you're not an (expletive) if you want to make the world a better place and you're playing with house money.
"And all this talk about trying to get everyone online. Sure, that has great global benefits, but aren't you really just trying to get your products in as many places as you can?"
'Lighten up, guys'
Michael Whalen, a professor of communications who studies film and pop culture at Santa Clara University, is a big fan of Judge's work. He compares him to maverick film director Robert Altman, an astute observer of American mores, and believes he's just the guy to do an "irreverent, cutting-edge" sitcom that holds a mirror to the tech world.
"People in the valley can be sensitive, but let's face it, some of them do take themselves a little too seriously," Whalen said. "This is a great way of saying, 'Lighten up, guys.'"
But will it resonate with viewers? In recent years, Hollywood has embraced Silicon Valley with mostly dismal results. While "The Social Network" did earn some Oscar attention, "The Internship," a buddy comedy set at Google, and "Jobs," a biopic about Apple's Steve Jobs, were box office duds.
Earlier duds
On television, the short-lived reality series "Start-Ups: Silicon Valley" was trashed by critics and tech insiders alike. Meanwhile, "Betas," an online-only comedy from Amazon.com, generated decent reviews, but little buzz.
Conversely, "Silicon Valley" seems to have a lot going for it, including Judge's impressive track record and the clout of a premium cable network known for quality TV. Also, early reviews have been positive. After a sneak preview at the South by Southwest festival, critics called the show "searingly funny," "hysterical" and "uncommonly insightful."
Perhaps it helps that Judge and Berg are no strangers to the tech community. After graduating from UC San Diego with a degree in physics, Judge briefly lived in East Palo Alto and worked as a test engineer before realizing he "really didn't fit in." Berg's father was a biophysicist and his brother is an electrical engineer who attended Stanford.
That familiarity, they say, was an impetus for them to work extra hard to capture the rhythms, jargon and inside jokes of the tech culture in their show.
"We were really concerned about getting it right," Judge said. "And it wasn't a matter of trying to get it right just for the sake of avoiding criticism (from techies). It's just a really interesting world and it feels better when you're putting something together that feels believable. We went deep into that world."
So deep that they worked with Stanford grad students to devise what would realistically come off as a groundbreaking compression algorithm developed by the show's lead character, a stressed-out software engineer (Thomas Middleditch). They then had the algorithm mock-pitched to a group of actual venture capitalists to get a feel for the dialogue it would spawn.
Still, the producers admit that it's a daunting challenge to whip up a viscerally engaging show from the world of programmers, coders and investors.
"There's a reason you see a ton of cop shows and hospital shows on TV," Berg said. "They've got lots of interesting stuff going on. But watching people type is not all that fascinating."
Follow Chuck Barney at Twitter.com/chuckbarney and Facebook.com/bayareanewsgroup.chuckbarney.
'Silicon Valley'
When: 10 p.m. Sunday
Where: HBO


text:
Our database lists more than 21,000 currently available products from more than 8,000 companies. The database also offers information on
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text:
Statement by Aerospace Industries Association President and CEO Marion C. Blakey on the passing of Rep. C.W. "Bill" Young (R-Fla.)
Today we mourn the loss of Rep. C.W. "Bill" Young, a true servant of his Florida constituents and the American people.
First elected to Congress in 1970, Young was the senior Republican member of House of Representatives, serving nearly 43 years. Working with eight different Presidents, Young was a tireless advocate on behalf of our military and the industries and people that support our men and women in uniform, whether on active duty, in the reserves or retired.
His perseverance and dedication to the armed services – in which he served for more than a decade – is a shining example to all Americans. Our condolences are with his family; he will be sorely missed.


text:
Topic: Please read Medical Updates:Statistics/Rare Cancers.
I just read this. I'm going to have to read it again to get the full weight of it....
Please read the article so that we can "brain-storm".
Why can not we contact therm? To say "Hey! We're over here---come get us!"
Could not the CC Foundation contact them , ORDR?
I wonder why they have not contacted "Us"/the Foundation------Do they not know of us?
Can we somehow send letters, emails, etc. to this ORDR?
Can we incorporate contacting them with CC Awareness Month?
Lainy, Slittle, Duke-------I know we can come up with something.............
I feel that since you have posted about how you have sent letters in the past, emailed all the TV shows , contacted local news stations in the past and none of them even bothered to reply ............that I won't hold my breath waiting for them to reply to my emails----perhaps after you have read the article in MEDICAL UPDATES under CHOLANGIOCARCINOMA at the top of the page.......maybe we can "Stand Up and be Noticed".


text:
Thursday, 07/02/1998
The Grey Hall, Freetown Christiania, Copenhagen, Denmark
Set 1: BOAFBirds of a Feather, CTBCars Trucks Buses, ThemeTheme From the Bottom, Brian and Robert, Meat[1], Fikus[1], Shafty, Fluffhead, GinsengGinseng Sullivan, PYITEPunch You In the Eye > Character Zero
Set 2: Ghost > Runaway Jim -> CaspianPrince Caspian, YEMYou Enjoy Myself
Encore: Simple
[1] Debut.
Noteworthy Jams: Birds of a Feather, Ghost (highly recommended), Runaway Jim, You Enjoy Myself
Average Song Gap: 4.71
Performers: Trey Anastasio, Page McConnell, Jon Fishman, Mike Gordon
Notes: This show marked the debuts of Meat and Fikus. Fans of stage banter will want to hear this show, as Trey was in a particularly chatty mood.
Song Distribution:
6 The Story of the Ghost
4 Billy Breathes
2 Junta
1 Stash
1 The White Tape
Songs by Debut Year:
This show was part of the "1998 Summer European Tour."
We got a rental car at the airport for 25 beans/day. She knew a little Czech and was fluent in Spanish. I was a French minor, but our German was non-existant. We used The Force to navigate our way N/NW to the German border and into Dresden. Now this used to be East Germany, and was not at all user-friendly as far as road signs go.
So, we motored on up to Berlin and on to the Danish border. Gas was RIDICULOUS in Denmark, so we turned around, crossed back into Germany, filled up, and recommenced towards Christiania. It was 50 beans to simply cross that bridge that took you over to the island where Copenhagen is located.
We camped at what used to be a gun-sight in WWII. Big grassy field right on the edge of the water. Underneath where the showers and laundry were used to be ammunition magazines and bunkers. Crazy history there. Anyways, like a 10 minute drive from the shed.
We pulled up behind Den Gra Hal(The Grey Hall) and parked about 7 cars down from the back dock of the venue. The back dock consisted of a door that you coukd open and drive a tractor inside. Nothing formal. I got out of the car and sure enough, they were soundchecking HaHaHa. I hadn't seen it since 95 I believe, so I remember being excited. The building itself is maybe 3-4 tractor trailers long. I estimate 800 capacity of this place.
The whole one side is a free-for-all graffiti wall for the locals- legally. So there were kids there throwin up some sweet tags all 3 days. I can't remember if the other side(Fish side) was the same. I do know the whole area was like a little park, with buildings scattered about. There was a skateboard half pipe a ways down the cobble stone path that ran in front of the venue. I remember a weed garden directly out front and down a ways that had a sign on the fence that said(in English too) No Pictures Please... We did anyways. I was young, my bad. I was blown away. Chilled outside and drank beers, met some dude who played some mean devil-sticks.
Anyways, the first night was like a "best of" type show, although it is the longest 2 setter I've seen(even longer than the Alladin.) Stash-> Cities was sweet. Moma was fun. Honestly this is the 1 of the 3 I listen to the least.
2nd and 3rd night second sets both start out disgustingly HUGE. Tweezer-> 2001 is 38 minutes of DOOOM!! The Ghost-> Jim from this next night is super HUGE taboot! I believe this Ghost isn't talked about as much because it's not an official release available as a SBD. I personally think this one is equal to the 7/6 version in Praha. Get a copy and hear for yourself. All 3 of these shows have something you should hear. The debuts and banter from this show and 6/30 are especially enjoyable and I find myself smiling each time I relisten.
Good, on-par Phish show.... Until you add this Ghost->Jim into the mix
4 stars
Overall: 1st set was OK, 2nd set other then Ghost was a let down. I would definitely listen to this Ghost you wont be disappointed.


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The Best and Worst of the Season So Far: Week of Aug 19-25
just for fun
91 Days and Love Live Sunshine come surging from behind to leap up the charts! Find out how your favorite shows fared in our weekly user rankings! ― Our team of reviewers are following 30 anime series of the Summer 2016 season and readers are rating each episode as the reviews go up. So let's have a look at what ANN readers consider the best (and worst) of the season. Keep in mind that these ranking...
Vice & Luna Bonus Round + Fanart Gallery
just for fun
Vice's Sword Art Online bluray preorder bonus finally came in, and it's delicious! PLUS: a Vice & Luna fanart gallery! ― Fanart Gallery Welcome to a Vice & Luna hiatus week! During the weeks where life happens or someone on our team needs some time off, we'll have one of these shorter little strips ready for you, and this week we're lucky enough to have some pretty awesome fanart to share. If you ha...
Yowamushi Pedal GN 3
This omnibus volume slows things down a bit from the heady days of the Welcome Race, but its exploration of the cast's emotions proves just as interesting. ― Competitive sports are a divisive pasttime, which is especially strange because they really don't have to be. Very few people are going to get into the sort of burning feud that Red Sox vs Yankees inspires over whether Dairy Queen or Baskin Robi...
Answerman - How Much Anime Can REALLY Fit On A Blu-ray?
Some anime come with 13 episodes (or more) crammed on a single bluray disc - is that really enough space to maintain HD picture quality? Justin gets into it. ― Mike (Toole) asks: How much anime will fit on a single Blu-Ray disc? Is a single BD-50 really enough for 13 episodes of subtitled 1080p anime? How much anime can comfortably fit onto a dual layer Blu-ray in full HD? For those who don't know, ...
Shelf Life - Aquarion Evol
James dives into the wacky, innuendo-filled world of Aquarion Evol and does his best to make sense of it all. Plus, all this week's new releases! ― I spent about twenty bucks on an anime figure last week (Eli from Love Live, in case you're wondering), and now I'm fighting to hold myself back from buying more. I used to buy figures on a regular basis, and nothing quite beats that initial thrill of se...
Please tell me! Galko-chan Episodes 1-12 Streaming
Rose Bridges takes a look at this underrated short gag series from earlier in the year and discovers a surprisingly educational (and filthy) anime like nothing else out there. ― When I was in high school, there was one huge girls' bathroom in the main hallway. For some reason, there was no such equivalent for the guys. This place became a sort of social gathering spot for all the girls in school, reg...
The List - 6 Strange Reinterpretations of Classic Literature
Legends never die, and old stories can always be made new again. Just add robots! Here are a few strange anime takes on memorable classic tales. ― Classic literature is a resource regularly mined for new visual adaptations, whether it's a Jane Austen romance or another mystery starring the unflappable Sherlock Holmes. These stories and their characters are immediately familiar to audiences around th...
Nisekoi 2 Sub.Blu-Ray 2
Nisekoi's second season comes to a close with no romantic resolution in sight, but is the journey more important than the destination? Theron Martin investigates. ― This release covers the second half of the series – episodes 7-12. This run of episodes is average by franchise standards, including both the weakest entries of the season and one of the strongest. Aside from a sad magical girl parody don...


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The FRP-48 from Batko is a universal pedestal pole mounts, 48". It is used for card access and intercom station. The FRP-48 is made up of aluminum and thus it is robust.
- For card access, Intercom station
- All aluminum
- Robust
- 0.125" aluminum base plate
- Locked pole cover at base
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Alexander the Great conquered the world by age 25. Mozart composed his first symphony by age 8. What have you done with your life?
Source: Time Troopers DVD game
Contributed by: Alicia
You kiss the back of my neck
I'm spinning to the ground
You run your strong fingers down my back
I can't hear a sound
You whisper things to me
So sweet I can taste your words
You're so close to me
I can feel our souls touching
You draw circles in my palm
Your love warms me to my toes, this I will never forget.
You loved me even if it was only for a minute
I hold onto that minute every night
You needed me even if only for a moment
I still hold onto that moment inside.
Christina Pagliarulo
Contributed by: Tina
If you look at the map you're only an inch away!
"Somewhere in your make-up there lies sleeping, the seed of achievement which, if aroused and put into action, would carry you to heights, such as you may never have hoped to attain."
Napoleon Hill
Source: Think and Grow Rich
Contributed by: katesanner
You never know how you affect other people.
Linda Shaw
Source: My Momma!
Contributed by: Kate
You have brains in your head. You have feet in your shoes. You can steer yourself in any direction you choose.
Dr. Seuss (1904 - 1991)
Source: Oh! The Places You'll Go!
Contributed by: Stephanie
"success is not a simple plan"
steve harvey
Source: the tyra banks show
Contributed by: miss lashae
Give me somewhere to stand, and I will move the world.
Archimedes (c.. 287 - 212 BC)
Contributed by: Angela
If God is willing to prevent evil, but is not able to
Then he is not omnipotent.
If he is able, but not willing
Then he is malevolent.
If he is both able and willing
Then whence cometh evil?
If he is neither able nor willing
Then why call him God?
Epicurus (c. 341 - c. 270 BC)
Source: The Riddle of Epicurus or Epicurean Paradox
Contributed by: dalaigoat
It's one of the paradoxes of spiritual practice: we need a path to travel where we already are. SAKYONG MIPHAM RINPOCHE explains how to create the causes and conditions for realizing the enlightened nature we already possess.
Each time I leave a meditation retreat, I'm struck by the level of speed and stress in our environment. I'm not just talking about Westerners. Ther first time I went to Tibet, life there was very simple, but when I returned three years later, cell phones were ringing and the distraction was visible, even while I was conducting ceremonies. Something else I've noticed lately is that we're bombarded with bad news. But the people I admire have always focused on the good news: that we have in our mind wisdom, compassion, and all the other elements of enlightenment.While living in stressful times does not ultimately affect our enlightened qualities, it does demand that we become more engaged in awakening them. To transform the environment, we must begin with our mind. We can't expect everyone else to change first. As my father, Chogyam Trungpa Rinpoche, was fond of saying, "It's easier to put on a pair of shoes than to wrap the earth in leather." The process of putting on a pair of shoes is the path of enlightenment.On the ultimate level, enlightenment is already here, but on the relative level we need to engineer its causes and conditions. The mind is a neutral situation, like a cotton sheet that we can dye any color we want, but unless we take hold of it, karmic tendencies--whatever habits we've ingrained in the past--will just take over. The practice of the path is slowly orienting that white cloth and coloring it the way we want. The path consists of three elements: view, meditation, and activity.View is our orientation, and how we orient our life is intimately connected with our motivation. Traditionally, the Buddhist teachings list three kinds of motivation: small, medium, and large. These levels of motivation describe how we evolve on the path of enlightenment. When we wake up in the morning, where is our mind taking us? Whatever it is, from motivation, everything else will arise.
If our motivation is small, we will use our day getting the "stuff" we think will make us happy--food, clothing, and friends. If it's a little bigger, we might add some yoga to make us feel better. We might even expand it further to think about the karmic consequences of our actions--but it's still all about "me". With a medium-level motivation, we're no longer so fixated on our own happiness; the basis of our actions is loving-kindness and compassion. We're maturing. With the largest motivation, we put the happiness of others before our own. This is the motivation of the Buddha. If we get up in the morning and the first thought that comes to mind is, "There are so many sentient beings; even if I amd the last person on earth, I will stay here to help them," that is a very big view. Motivation is just an attitude, and it's free. So why not have a big motivation?
Why is view so important? View is how our mind is oriented, and the way our mind is oriented determines what we get. Our realization is based on the size of our view. The view of enlightenment is that we are taking charge of our own destiny. Unless we take the mind where we want it to go, the environment will take the mind where it wants it to go.
By setting our view every morning, we become very good at supporting ourselves in the second element of the path, meditation. Meditation is essentially a dualistic process in which we place our mind on an object. When we place our mind on something, the mind absorbs its qualities, because we're becoming familiar with it. This isn't particularly a spiritual truth; it's our everyday reality. For example, if the object is the anger you feel toward your spouse, you become more familiar with anger, soaking up its qualities like a sponge. In the end, that meditation leads to action. You yell at your spouse or stomp out of the room.Meditation is a proactive approach to this reality of mind. We practice choosing the object rather than being led by whatever thoughts and emotions randomly beckon. We steep our mind in qualities that lead it forward. We begin with the stabilization technique called sharmtha, "peaceful abiding, " in which we focus on the breath. Through this practice our mind becomes settled and workable. Why is this important? We may have good intentions, but if we can't control our mind, we can never enact them. For example, we want to be compassionate but we get discursive, distracted by our mental ups and downs. Before we can cultivate compassion, we need to possess our mind. That's what we do in stabilizing meditation, where we calm down and experience the space of mind just being there. From that, our mind is much less speedy.The mind resting peacefully has incredible implications. If you're present for the moment, you're present for your life, and you can therefore observe what's going on. If you can observe what's going on, you can make judgements, deciding where you want to go. At this point--known as the present moment--you can change your karma. You can reorient your whole path, because in terms of the future, you're in the driver's seat. You are getting more enlightened. You are waking up.We actively reorient ourselves in contemplation, the second kind of meditation, known as vipashyana, "clear seeing." Now we take a thought as the object of our meditation. For example, we can focus on our motivation, stated very simply: "I want to meditate," "I want to develop compassion," "I want to tread on the path of enlightenment," or "I want to become enlightened, no holds barred." At other times we might contemplate a quality--generosity, exertion, discipline, or patience--that could support our motivation.This is a practice of fabricating our enlightened qualities so that our mind naturally turns in their direction. We know that we're innately compassionate, and we also know that we don't feel right now because there's a blockage. So we contrive our buddhanature in order to reveal it. We call this relative understanding. That understanding may be brief, but we should not be discouraged . By becoming familiar with the view, we are clarifying our future.It's one thing to have the attitude of enlightenment and another thing to act in an enlightened way, which is conduct or activity, the third element of the path. If we have proper understanding of our motivation and are getting used to our enlightened qualities, chances are we can deal with speed and stress more effectively. First we can create space in our mind to see where we are. Then we can reorient ourselves by remembering what we're doing. That allows us to say, "Sure, I'm tired and in a hurry and my phone is ringing again. Yet I can stay on the path by sticking with the ten percent of my mind that really wants to do this." The more we develop the tools to move forward on the spot, the less influence the other ninety percent of our mind will have. Our karmic tendency to drift into agitation and discursiveness will incrementally decrease. View, meditation, and conduct give us a way to remember what we're doing and why we're doing it, and then enact our own enlightenment. As we do that, we are stepping on the path. We're making progress.Sakyong Mipham Rinpoche is the spiritual leader of Shambhala, an internation network of Buddhist meditation and retreat centers. He is the author of Turning the Mind into an Ally and Ruling Your World.
Sakyong Mipham Rinpoche
Source: March 2008 Shambhala Sun Magazine
Contributed by: Bird
Copyright © 2016 Gaiam, Inc.


text:
PBS' This Emotional Life and Autism Speaks Present: "Growing Up With Autism"
TUNE IN – "Growing Up with Autism" webinar
Tuesday, April 27, 1-2 p.m. EDT
Join a panel of scientists, parents, and individuals with an autism spectrum disorder (ASD) to learn what it is like "Growing Up with Autism." Dr. Geraldine Dawson, Ph.D, the Chief Science Officer at Autism Speaks and Research Professor at UNC Chapel Hill will lead a discussion with Connie Kasari, Ph.D. (UCLA), Holly Robinson Peete, and John Elder Robison, to address the challenges that face individuals with an ASD and their families as they are initially diagnosed, navigate peer interactions and age out of services as they enter adulthood.
The panelists will also focus on the different needs and abilities individuals with an ASD have in the hope of generating acceptance and support in the community. This poignant webinar will combine professional experts with personal experience to offer unique insights and perspectives that will be valuable to all who are touched by this increasingly common spectrum of neurodevelopmental disorders.
To register for the free webinar, please visit https://www1.gotomeeting.com/register/563407008.
Stay informed about "This Emotional Life's" on-going webcasting events with thought leaders in the fields of mental health and wellness by signing up for their bi-monthly newsletters.
If you miss the webinar, we will have information soon about how you can view it. Please stay tuned!
April 26, 2010 at 3:45 pm
I am Maltese and have two authistic children. Is it possible to take part?
April 26, 2010 at 5:10 pm
Hello! Is this going to be available to watch at a later time? I have an appointment, but I'm very interested. Thanks
April 26, 2010 at 6:38 pm
Yes I too am interested to know if we can tune in at another time or hear a previously recorded version somehow later?? Thank you, I soooo want to attend/tune in but I would be late to it.
April 27, 2010 at 2:20 pm
I hope to hear how we can view it at a later time. I will be at work but would have loved to watch this. I love Holly and enjoy watching her on Celebrity Apprentice. We were just recently diagnosed with our son and the paperwork to get assistance for therapy, insurance issues and exclusions, the school… it's very overwhelming.
May 1, 2010 at 12:44 pm
We missed the presentation and want to see it. Recording available?


text: "Really nice biz card that stands out from the others! I just wish there were a few more options to personalize a bit more. I received my cards faster than I thought I would, which was REALLY nice! And I love the feel of the cards - nice, quality product. Thank you, tiny prints!"


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POSITION: Left Wing
SHOOTS: Left
BIRTHPLACE: Freiburg, DEU
DRAFTED: ATL: 2000-2 overall
Calder Memorial Trophy (1)
Collected 64 points (26-38=64) in 80 games with San Jose…Added 11 power-play goals and five game-winning tallies…Ranked fourth on team in scoring and T-12th in the NHL in power-play goals…Suspended two games by the NHL (3/16)…Made first appearance in Ottawa (12/2) since being traded and registered an assist while drawing two penalties that led to power play goals…Played in 600th career game at STL (11/4)…Tied career-high with four points (1-3=4) vs. NJ (10/27)…Scored 300th
career goal vs. ATL (10/16)…Notched nine points (3-6=9) in 18 playoff contests…Set a Sharks franchise record for fastest goal, scoring 28 seconds into Game 1 of Western Conference Quarterfinal vs. LA (4/14).
Ranks first in the NHL in power-play goals (128) and game-winning goals (58), third in goals and fifth in points since entering the NHL in 2001…Has collected 689 points (325-364=689) in 669 career contests in nine seasons with Atlanta, Ottawa and San Jose…Winner of the 2002 Calder Memorial Trophy, named to the 2006 NHL Second All-Star Team, the 2007 First All-Star Team and four NHL All-Star Games (2003, 2007, 2008 and
2009)…Has represented Canada at the last two Olympics winning a gold medal in 2010.
Collected 64 points (26-38=64) in 80 games with San Jose…Added 11 power-play goals and five game-winning tallies…Ranked fourth on team in scoring and T-12th in the NHL in power-play goals…Suspended two games by the NHL (3/16)…Made first appearance in Ottawa (12/2) since being traded and registered an assist while drawing two penalties that led to power play goals…Played in 600th career game at STL (11/4)…Tied career-high with four points (1-3=4) vs. NJ (10/27)…Scored 300th
career goal vs. ATL (10/16)…Notched nine points (3-6=9) in 18 playoff contests…Set a Sharks franchise record for fastest goal, scoring 28 seconds into Game 1 of Western Conference Quarterfinal vs. LA (4/14).
Tallied 82 points (39-43=82) in 82 games in first season with San Jose…Ranked eighth in the NHL in goals and T-15th in points…Finished second in the NHL in power-play goals (18) and first in game-winning goals
(nine)…Notched 600th career NHL point with an assist vs. CHI (1/28)…Had a seven-game point streak (5-4=9, 1/6-1/18)…Tied Sharks franchise record for shots in a period with seven in first, including a goal, vs. STL (12/3)…Picked up second hat trick of the season vs. PHI (11/20)…Scored a hat trick (3-1=4) in home debut vs. CBJ (10/8) that included a converted penalty shot and a franchise-tying plus-6 plus/minus rating…Registered 13 points (2-11=13) in 14 playoff games…Posted three assists in Game 2 of Western Conference Semifinals vs. DET (5/2)…Missed one playoff game due to injury (4/18).
One of four Senators to appear in all 82 regular season games…Led team in goals (39), power-play goals (15), game-winning goals (six) and shots (258)…Ranked second with 18 multi-point games and third in scoring…Ranked seventh in the NHL in power-play goals and tied for ninth in goals…Recorded 500th NHL point with an assist vs. DAL (12/20).
Led Ottawa in goals, third in assists and points...Plus-33 rating ranked third in the NHL...Surpassed 40-goal mark (41) for the fourth time in his career...Ranked tied for fourth in NHL with eight game-winning goals...First Senators player to have three consecutive multi-goal games (6-1=7, 12/12-12/15)…Saw consecutive games played streak end at 207 (1/13)…Recorded two four point efforts (1-3=4 vs. MTL, 2/9/08) and (3-1=4 vs. BOS, 3/11/08)…Named to Eastern Conference All-Star Team, but missed game due to injury…Had one assist in four playoff games…Missed 11 games with shoulder injury.
Named to the NHL's First All-Star Team...Set Ottawa team record for most points in a season (105) while tying his own record for most goals (50)…Became first NHLer to record back-toback 50-goal seasons since Florida's Pavel Bure (1999-2000, 2000-01)…Set career-high with 55 assists…Finished second in the NHL in goals and fourth in points…Led Ottawa with 28 multi-point games…Scored 24 points (11-13=24) during season-high 16-game point streak (2/8-3/15)…Notched 22 points (7-15=22) in 20 playoff games as Ottawa advanced to Stanley Cup…Ranked tied for first in NHL in playoff scoring.
Recorded 103 points (50-53=103) in 82 games with Ottawa becoming first Senators player to record 100 points and 50 goals in a season…Had 29 multi-point games…Had a team record 22-game point streak to start season (17-21=38, 10/5-11/29) the second-longest streak in NHL history from start of a player's tenure with a team (23, Wayne Gretzky in 1988-89, Los Angeles Kings)…Recorded career-high four goals at TOR (10/29)…Named to NHL's Second All-Star team...Collected 12 points (3-9=12) in 10 playoff contests including 10 points (2-8=10) in Eastern Conference Quarterfinal series against Tampa Bay.
Tallied 24 points (14-10=24) and 58 PIM in 16 games with Bern (Switzerland)…Missed 14 games due to injury…Had four points (3-1=4) and 22 PIM in 11 games with Ak Bars Kazan (Russia).
Collected 25 points (13-12=25) in 31 games with Atlanta...Missed first 51 games due to injury.
Became first Thrasher player to score 40 goals in a season…Scored first NHL hat trick at PHI (1/13)…Most Valuable Player of 2003 NHL All-Star Game following a four-goal performance…Youngest player in NHL All-Star Game history to score a hat trick and one of only five players to score four regulation goals…Logged careerhigh 29:05 in ice time vs. FLA (3/7).
Won Calder Memorial Trophy and named to NHL All-Rookie Team...He and teammate Ilya Kovalchuk finished first and second in NHL rookie scoring - first time since Rangers Brian Leetch and Tony Granato did it in 1988-89.
Led Wisconsin (WCHA) in goals and assists in 2000-01…Finalist for 2001 Hobey Baker Award…Named to the 2001 NCAA West First All-American Team…Helped Wisconsin win 1999-00 WCHA regular season title...Named 2000 WCHA Rookie of the Year…Led Calgary to Doyle Cup regional junior A championship and was first in scoring with 127 points (70 goals and 57 assists) in 1998-99…Canadian Junior A Hockey League Player of the Year.
Won a gold medal at 2010 Olympics with Canada…Ranked tied for second on team in goals and scoring with seven points (4-3=7) in seven games…Won a silver medal with Canada at 2009 World Championship…Named MVP of 2008 World Championship leading tournament with 12 goals and 20 points in nine games…Canada claimed silver medal…Represented Canada at the 2006 Winter Games for first time...Won gold medals at 2004 World Cup and 2004 World Championship with Canada…Led 2004 World Championship with eight goals and 11 points…Won gold medal at 2003 World Championship…Skated for Canada at 2000 and 2001 World Junior Championship.
Acquired by Minnesota from San Jose in exchange for Martin Havlat, July 3, 2011; Acquired by San Jose along with a 2010 fifth round draft pick from Ottawa in exchange for Milan Michalek, Jonathan Cheechoo and the Sharks 2010 second round draft pick, Sept. 12, 2009; Acquired by Ottawa from Atlanta in exchange for Marian Hossa and Greg de Vries, Aug. 23, 2005; Selected by Atlanta in the first round (2nd overall) of the 2000 NHL Entry Draft.
Dany Heatley is single and resides in Kelowna, B.C. during the offseason…Nicknames are "Heater"
and "Heats"…Enjoys golfing and boating during his time off from hockey…First job was as an electrician's
apprentice…Brother Mark plays hockey professionally in Germany and father Murray played
15 years professionally…Lists the fans as his favorite part of Minnesota…If not for hockey, would
like to be a musician…Enjoys listening to any music teammate Devin Setoguchi chooses before
games…Possesses a hidden talent for cooking…Favorite cuisine is Italian…Lists Major League
as his favorite movie and "Entourage" as his favorite television show…Other than hockey, favorite
sport is baseball…Favorite website is TFLN.com…Involved in Garth Brooks Teammates for Kids.


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Cumberland Valley Animal Shelter will be closed to the public from Jan. 23 to 30 while the organization moves to its new location. No animals will be accepted during that week and no adoptions will be completed.
Antietam Humane Society, 8513 Lyons Road, Waynesboro, will take stray animals for the week CVAS is closed.
CVAS will open at 11 a.m. Thursday, Jan. 31, at 5051 Letterkenny Road West, Chambersburg.
Anyone interested in helping the shelter move should call 263-5791.
Location, ST | website.com


text:
Exceptionalism misunderstood
By Clifford May
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text:
Wednesday Oct 25, 2006
Where spellcheqk is just another word.
Recent Posts
- My last Blog post ever!!!!!!!!!!
- Javascript Pet Peeves
- Typography (not spelling!)
- LA to New York (That's what planes are for)
- Application Express and Oracle Spatial
- Very cool list of CSS tools.
- More prepackaged applications than you can shake a stick at.
- Go Firefox!
- Google Code Search and Me
- You learn something new everyday!


text:
The recent growth in the vaccine market has led to renewed interest in using adherent human cell lines for vaccine production. Traditionally, small-scale adherent cell line production has been carried out in roller bottles or T-flasks. Over the past few years, however, a number of companies have found multi-tray disposable bioreactors an effective method for producing high-quality drug products using adherent cells. These disposable, expandable systems have also facilitated scale up from laboratory to clinical-scale.
Given the use of adherent cell lines in vaccine development in the 1970s, methods to facilitate the scale-up of adherent cell production were needed. First, roller bottles were developed as a logical progression from glass bottles. Roller bottles were then further refined by industry to include various sizes and shapes, and equipment for automated handling and processing was introduced. A significant drawback of a roller bottle, however, is that it is an open system that requires repeated opening and closing of individual bottles. For production, this is not an efficient process and requires increased deployment of labor and equipment. A better approach was needed.
In 1978, scientists at Rentschler Biotechnologie GmbH in Germany described a multi-tray cell-culture system designed to improve efficiencies for producing interferon beta with adherently growing human fibroblasts. In order to scale-up production without changing methods and format, they glued T-flasks together. This invention, referred to as a multi-tray bioreactor, later became a standardized industry device, and has been implemented by many major pharmaceutical manufacturers for the production of vaccines for polio and other diseases.
A Flexible Option
Today, multi-tray bioreactor technology may be a suitable solution for developing vaccines using human cell lines. This flexible, closed-system technology was developed as a way to easily scale up production directly from a single laboratory cell culture flask. An individual tray is similar to a commonly used tissue culture flask, but with an expanded surface area. A single tray can be used exactly like a common 175 cm2 cell culture flask in preclinical work, and then, as more cells are needed, researchers can use the multiple tray versions to scale up adherent cell propagation. The system also facilitates quality control, because cells are easily examined by inverted microscope.
Because no cell line or equipment changes are needed when scaling up production with multi-tray bioreactors, using this technology can speed up new drug development. Cell propagation may be performed on a small- or large-scale, depending on the amount of cell mass required. Another benefit is that multi-tray systems are designed for single-use, and thus eliminate the need for efforts and infrastructure required for cleaning and validation.
Using adherent systems also can facilitate product quality when using human cell lines. Manipulating human cell lines for propagation in a suspension format heightens the risk of inadvertently producing antibodies and other proteins with distorted three-dimensional configurations that render the product useless. This risk is avoided with adherent systems.
Vaccines have been undergoing a resurgence over the past few years. Many institutions and companies are involved, and they must address the ever-present issues of productivity and cost-efficiency. Because preclinical studies can take 5 to 10 years, many companies try to keep multiple drug or vaccine candidates moving through the drug development pipeline at the same time. Multi-tray bioreactor systems provide a flexible and cost-efficient approach to implementing multiple projects simultaneously.
Case Studies: Multi-tray Bioreactors in Production
As the case studies below explain, several companies that are using multi-tray bioreactors have found the method allows for efficient production of high-quality products for preclinical and clinical studies.


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Dear Angie: We just bought a house and found mold in the air ducts. We talked to a few companies about cleaning the ducts. One wants $1,200 and the other $3,600, and the only real difference seems to be that one takes the a/c coils out to clean them and the other does not. Do they need to be taken out? Also, how can we find the true source of the problem to make sure it does not reappear? Would it be better to replace the duct work rather than clean it? If we have mold in the duct work, could we also have it in the walls or under the carpet? That thought scares me to no end. We are having a baby in four weeks, and this has been a nightmare already. What's your advice?
- Clint B., Dallas
Dear Clint: Mold can certainly grow in air ducts, but highly rated air duct cleaning professionals I've spoken with say it's not a common occurrence. Did you have anyone, other than the air duct cleaning company, test first to ensure you have mold?
If not, that's where you should start; and because you live in Texas, you're more likely to get accurate advice from a qualified mold tester. That's because, in 2005, Texas became the first state in the U.S. to regulate the mold remediation industry and require licensing for mold professionals. Now a company that inspects for mold can no longer do the remediation, which poses a huge conflict of interest, as a company that can both test for and remediate mold has incentive to "find" mold. A professional mold test sent to an independent laboratory can identify the type and severity of the mold.
While it's entirely possible that you do have mold in your air ducts, such claims are also a common scare tactic used by some less than scrupulous air duct cleaning companies. That said, if you do have mold in your air ducts, I've been advised by industry professionals that it would be best to remove the components, like the a/c coils, from the HVAC system to perform the most thorough cleaning. The average air duct cleaning job - properly done - takes several hours and costs $350 to $500.
To address your concern about hidden mold, yes, it can also grow in places where you can't see it. In fact, it thrives in dark, concealed areas where it has access to moisture as a food source. So if you have moisture behind walls or under floors, then mold could be a concern there as well. That's why I recommend calling out a mold tester first. He can help determine if mold is in hidden areas and recommend the best course of action. The key to ridding your home of mold is to first identify the source of the problem; typically a water leak. Ridding your home of mold without addressing the issue will just lead to a recurrence of the problem.
This is certainly one job you only want to pay for once, so have your home properly tested and, if necessary, remediated by licensed, reputable companies.
Contact Angie Hicks, creator of the Angie's List website, with your question at firstname.lastname@example.com.
Location, ST | website.com


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NH, nation's healthiest state, not 'investing' enough in anti-smoking campaigns say activists
The state's anti-tobacco program subsisted on just more than $1 million in federal grant money, one of the lowest budgets in the nation. Not one cent of that funding comes from the state. All tobacco taxes are sent back to the state's general fund.
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