text:
Implications for the androgenic regulation of IGFBP-2 in the development of metastatic and androgen independent prostate cancer
2008 2008
Abstract (summary)
The insulin-like growth factor (IGF) axis consists of two ligands (IGF-I and IGF-II), two receptors (IGF1R and IGF2R), as well as a family of closely related IGF binding proteins (IGFBP 1-6). It is generally considered that altered expression in IGF axis members is associated with the development of several cancers. Elevated expression of IGFBP-2 is directly correlated with both the in vitro aggressive behavior and clinical presentation of metastatic ovarian, breast, adrenal, and central nervous system cancers. However, a role, if any, for IGFBP-2 in metastatic androgen independent prostate cancer (AI PCa) is unknown. Additionally, while alterations in IGFBP-2 expression are associated with progression to AI PCa, published reports regarding the influence of androgen treatment on the most commonly utilized androgen sensitive (AS) PCa cell line, LNCaP are contradictory. Therefore, we undertook an analysis of first, the influence of androgen treatment on IGFBP-2 expression in LNCaP, and second, the role of IGFBP-2 in the metastatic nature of AI PCa. In summary, we report the following in regard to the regulation of IGFBP-2 expression in LNCaP human PCa cells following treatment with the synthetic androgen R1881: (1) R1881 treatment produces an initial increase in steady state levels of IGFBP-2 mRNA, followed by a time dependent decrease in steady state levels of IGFBP-2 mRNA, (2) R1881 treatment results in decreased levels of intracellular IGFBP-2 in Triton-x-100 soluble locales, as well as the increased nuclear localization of IGFBP-2, and (3) through the apparent action of an as yet unidentified serine protease, R1881 treatment results in the limited proteolysis of IGFBP-2 and a subsequent decrease in intact extracellular IGFBP-2. Furthermore, we demonstrate that (4) IGFBP-2 is a substrate for androgen-induced proteolysis in PCa cells with a functional androgen receptor (AR), (5) the ability of IGFBP-2 to undergo androgen-induced proteolysis is attenuated greatly with progression to AI and is inversely correlated with in vivo metastatic potential, and (6) androgen-induced IGFBP-2 proteolysis results in decreased binding to IGFs, and thus has functional consequences. In regard to the role of IGFBP-2 in the facilitation of the aggressive phenotype attributed to metastatic PCa, we show that IGFBP-2 treatment (7) increased LNCaP levels of phosphorylated focal adhesion kinase (FAK) in both a concentration and time dependent manner, (8) significantly increased the invasion of LNCaP cells, and (9) increased the migration of non-metastatic, poorly motile LNCaP cells. In summary, our results indicate that IGFBP-2 expression is repressed in AS LNCaP human PCa cells in an androgen containing environment, resulting in a significant decease in extracellular IGFBP-2 levels. Furthermore, our results indicate that decreases in secreted levels of IGFBP-2 achieved via extracellular proteolysis are lost with progression to AI, and this increase in extracellular IGFBP-2 may facilitate the metastatic behavior of AI PCa cells.
Indexing (details)
Cellular biology;
0379: Cellular biology
0719: Physiology


text:
FURNITURE: One of a kind piece, custom refinished in linen blue over deep charcoal chalk paint. Hand aged and distressed solid brass hardware. Features 3 deep bottom drawers and 4 side shelves. Asking $400 but all offers entertained. Hurry - this one will go fast!More info Email a friend
FURNITURE: Olive green and beige sofa and love seat 3 tables included. Will also sell separately for good price. Asking $500 for entire set. $300 sofa, $100 love seat, $100 for 3 tables. Some decor free.More info Email a friend
BARGAINS/SUPER SAVERS ($100 OR LESS): Folding Commide for an Elderly or Handicapped personMore info Email a friend
HOBBIES/COLLECTIBLES: In great condition, this mounted deer head is a collectible or perfect for the sportsman enthusiast. Will take best offer.More info Email a friend
HOBBIES/COLLECTIBLES: In great condition. Legallly hunted. Perfect for the outdoor enthusiast. Will take best offer.More info

subset: commoncrawl


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Sister Does Not Need Ariel Winter's Money (Recap)
Shanelle Gray is married to David Barry Gray ... who is an heir to the Pepsi fortune. His grandfather was one of the founding members of Pepsi Cola.
David's grandfather, Philip Rubenstein, owned 23 of the original Pepsi plants and, with the help of a guy named Al Steele, took the company nationwide. Rubenstein served as the President of Pepsi Cola in the 1950s and amassed a fortune.
As for what happens to the untold millions of dollars ... Rubenstein died in 1997 and was survived by his wife, 2 daughters and 6 grandchildren, one of whom is David. Rubenstein's wife died in 1998. Short story -- David -- an actor - is in line to inherit a big chunk of the family money.
Family money aside, Shanelle and David are doing well with their 2 acting businesses -- Gray Studios in L.A. and Gray Studios in Orange County. The business is so successful, it's expanding to NYC next year.
And Shanelle -- who gave up a fairly successful acting career to raise their 2 daughters -- is now back in the acting game and getting gigs.
It seems Chrystal Workman, the mother of Ariel and Shanelle -- doesn't know much about her older daughter, who was taken away from her years ago and placed in foster care. It would seem she has no idea Shanelle is more financially secure than the entire cast of "Modern Family." - more on this story
TMZ submitted this story.
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Kieran Read turned down a long-term contract extension and sabbatical option, but there are few fears the All Blacks No 8 will take his talents overseas at the end of next year.
Read's recent one-year deal sparked concern he was weighing up offshore options after a number of senior All Blacks committed their immediate futures to New Zealand rugby.
The Sunday Star-Times understands that, during protracted negotiations, the New Zealand Rugby Union placed various offers in front of Read, including an extension through to the World Cup in 2015.
In what is becoming an increasingly familiar scenario, "long-term leave options" granted to All Blacks captain Richie McCaw, Dan Carter and Ma'a Nonu, were also used as an incentive for Read to sign an extended deal.
"It was more about where I wanted to be. I've got a family to look after - it's just the way it worked out that I only signed a one-year deal," a coy Read explained. "All going well, we'll see what happens next year."
Read's leadership is invaluable for the Crusaders and All Blacks and he appears to have shown the same nous off the field.
Rebuffing the NZRU may be an intelligent move from Read's savvy management in the modern climate.
The governing body's lucrative sponsorship deal with AIG is understood to have been a factor in his decision, and with future funds likely to be freed up for the All Blacks' heavy-hitters, Read could be a major beneficiary in his renewed contract next year.
"In today's world sometimes a one-year deal is best for the player because he will back himself to play well, and he will have a stronger bargaining point next time," All Blacks coach Steve Hansen said.
"I don't think Kieran is thinking at all about leaving."
All Blacks management consider Read a future captain and he is likely to take the reins from McCaw against Italy in Rome next weekend, and again when the openside flanker takes six months off next year.
The NZRU's preference was to secure the 27-year-old's services for at least the next two years and they have essentially been forced back to square one.
"We will almost immediately start to negotiate with him for a bit longer," NZRU chief executive Steve Tew said. "His people would prefer to do a one-year deal and come back to the table early in the New Year. We will be ready and welcoming.
"We certainly don't believe there is any danger of him going overseas, but he's only committed for one-year so he's a free agent come the end of 2013. There are no immediate alarm bells."
Tew confirmed Read would be granted "a decent break" in his next contract.
The common trend of New Zealand's top-tier players being offered sabbaticals could soon be a major issue and source of frustration for Super Rugby coaches, who may be without their best talent on a regular basis.
"For our long service players we are flexible about them taking long-term leave, a decent break at some point," Tew said. "Realistically, if we are going to get Kieran through to 2015 and beyond there will have to be some concessions in his playing schedule. That will be individually tailored as they all have. We've done it with Richie, Dan, Ma'a and there will be others."
Tew also warned Read he could be left out of pocket by the keeping his options open.
"We are comfortable with where Reado is. He's got a big future in New Zealand rugby. I'm not going to be picking the next All Blacks captain but he's the favoured option, hopefully that comes to pass. But like all of these things, if you sign a one-year deal and you get a long-term injury, you don't have the same security."
- Sunday Star Times
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PHILIPPINES: Tanduay builds expansion war chest
Tanduay Holdings Inc has earmarked a PHP2 billion to invest in an expansion that may include acquisitions between now and 2007.
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2 cycle oil to gas mix ratio for chainsaw
kgb answers » Home & Garden » Automotive » 2 cycle oil to gas mix ratio for chainsaw
Tags: two-stroke oil, motor oil
Thursday, February 02 2012
Source: http://www.ordertree.com/cms/Poulan+Chainsaw+FAQ/242.html#howdoimixthegasandengineoil
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CLEVELAND – He might not be the Scott Kazmir some Twins remember from his younger days. The problem on Friday night was that he was the Scott Kazmir they remembered from May.
The lefthander shut down the Twins for the second time this season as the Indians rolled to a 5-1 at Progressive Field, halting the Twins' three-game winning streak. Kazmir held the Twins to one run over seven innings while striking out seven.
The Twins entered the game with a little momentum after scoring 22 runs while sweeping the White Sox in a three-game series. The only run the Twins got Friday was Brian Dozier's solo shot off Kazmir in the sixth, his third home run in as many games.
Kazmir beat the Twins for the second time this season and now has a 2.08 ERA against them in two starts. He used to power fastballs reaching 95 miles per hour past hitters with regularity. On Friday, he waited until his final inning to touch 94 on the radar gun.
Was it the same Kazmir, Twins manager Ron Gardenhire?
"He still has velocity, but nothing like he did way back," Gardenhire said. "He used to fire the ball all over the place, keep you off balance and keep you nervous, too. He'd miss here and there and then he would come in with the nasty pitch. Here, he has a little better command of himself on the mound right now."
Twins lefthanded hitters were 1-for-14 against Kazmir, the only hit being a double by Joe Mauer in the first inning. Kazmir (4-4) shut down the next two batters to get out of that inning. The same thing happened in the seventh. Trevor Plouffe hit a one-out double. Kazmir painted the outside corner for strike three against Oswaldo Arcia, then painted the bottom of the strike zone to retire Clete Thomas.
"He looks like he's pretty much back to where he was to me," Twins first baseman Justin Morneau said.
Kazmir, 29, was 55-44 in six seasons with the Rays, but he took such a fall — he went 9-15 with the Angels in 2010 — that he spent last season pitching in the Atlantic League for the Sugar Land Skeeters and in the Puerto Rican winter league with Gigantes de Carolina.
The Indians signed him to a minor league contract with an invite to spring training. It looks like a wise move — especially since the Twins are in the same division.
Cleveland took a 1-0 lead in the second inning when Michael Brantley and Mark Reynolds hit back-to-back doubles.
The Indians' second run came in the third when Drew Stubbs scored on a sacrifice fly to second baseman Dozier, who was in super-short center field when he caught a flare by Jason Kipnis. Dozier dropped the ball while making the exchange from glove to hand, allowing Stubbs to score from third.
Samuel Deduno (3-2) held the Indians into the seventh inning before giving up a leadoff single and walk before being removed. Cleveland got an RBI single by Stubbs and a two-run single by Kipnis to put the game away.
"We needed those clutch hits," Dozier said. "At the same time [Kazmir] did a good job locating the ball, especially inside to righties."
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Grade I winner and millionaire Include was represented by his first winner when his daughter, A Slick Chic, won May 9 at Calder Race Course. Bred in Kentucky by Nancy C. Shuford, A Slick Chic won at two furlongs in :22.09 for owner/trainer George A. Stephens. She is out of the winning Silver Deputy mare Kidnap.Include (Broad Brush--Illeria, by Stop the Music) stands for $12,500 at Brereton C. Jones' Airdrie Stud near Midway, Ky.
A Slick Chic First Winner for Millionaire Include
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Collaboration with Angelia61 stock with the background
3d and photomanip
Horses, textures my own
horse foal sun set rise brown orange animal
Wonderful work Laura!
oh laura, this picture is delightful, a beautiful image, well done,dawnx
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Hello Laura! how's things? I love your picture – beautifully done as always.
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Friday, 26 August 2016
Last updated 2 hours ago
Jan 2 2014 | 1:57pm ET
SAC Capital Advisors is going out on a high note.
The legendary hedge fund, which is returning outside capital after settling criminal insider-trading charges, was up 20.1% through Dec. 27, it told investors Monday. The average hedge fund is up by only single digits this year.
SAC rose 1.88% last month.
SAC agreed to cease managing outside capital and become a family office in November, pleading guilty to insider-trading charges as part of a deal with federal prosecutors.
Aug 25 2016 | 8:55pm ET
The emergence of private credit as a replacement for traditional bank financing...
Aug 24 2016 | 9:59pm ET
Looking for real estate investments but the typical real estate fare isn't cutting...
Aug 9 2016 | 2:39pm ET
The age-old financial concept that higher yields are the result of higher risk and...


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1980 Diesel Citroen HY van Newly built, painted & MOT £19000
picture is of van restored / converted by us
we have for sale 2 x 1960s citroen h vans they are to be restored and converted for food/ promotional use. level of restoration and price is negotiable .....
Please note pictures are of a van previously restored by us -I would be happy to supply pictures of claudette on request
Claudettes story
born in 1969 in Limoges with perfect round rear wheel arches.
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We have h vans and other vehicles for hire, short or long term hire can be adapted to your needs and vinyl wrapped if required.We also renovate, convert and sell vans outright.
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This is a 1985 Citroen HY van, completely rebuilt to a professional catering standard by H Van world. The van itself has no engine and has to .....
Citroen H van from 1970, I imported from the Netherlands in 2013 and since then have been slowly working on a complete overhaul, has a catering hatch put in, replacement diesel engine, the brakes have .....
In 1964 Citroen launched the new model with one big windscreen, instead of the split.
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JUST SOLD SORRY, 1972 Citroen HY van, ford pinto conversion. Raised roof. Just finished this week. SORRY ALREADY SOLD - other vehicles available please contact for more information 01274670742 07908187589.....
Manufactured in 1973. In 2012 was converted to a light catering vehicle and has been used as such since then. The vehicle is tax exempt. It has a UK registration with DVLA.
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Kristofff wrote:Hi,
Toby - I think you should know it - if I try to access www.splocs.com from a chrome web browser, I get warning from Google that the website contains malicious software. Somebody hacked probably and put sth on the server???!
Users browsing this forum: alamos_kiter, foilholio, kitingkt, Teabageppo, tegirinenashi and 23 guests


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Staybridge Suites Opens in St. Petersburg, FL
Thursday May 1st, 2014 - 10:35AM
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ST. PETERSBURG, FL—IHG has opened the Staybridge Suites St. Petersburg here.
The new 119-room hotel is owned and managed by Menna Development & Management, Inc. and is franchised by an affiliate of IHG. The property is the first Staybridge Suites in the city and the second for the brand in the greater Tampa Bay area. The Staybridge Suites St. Petersburg features 4,000 sq. ft. of event space, including a 2,200-sq.-ft. ballroom with floor-to-ceiling windows.
"The Staybridge Suites St. Petersburg is the first new build hotel to open in the downtown St. Petersburg area in over a decade, so today's grand opening celebration is exciting not just for us, but for the entire community," stated Robert Radomski, vp, Brand Management, Staybridge Suites and Candlewood Suites brands.
Tags: Staybridge Suites • St Petersburg • FL • opening • IHG • Hospitality • Brands • Openings •
Technology has transformed travel. It's that simple. From virtual-reality tours to mobile check-in to storing and personalizing guests' preferences, technology is continuing to influence the way we stay and vacay, so to speak. And it's also continuing to impact the way hotels do business. It comes down to this equation: guests' demands + hotel delivery = happy customers.
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More Book Lust
Recommended Reading for Every Mood, Moment, and Reason
Nancy Pearl
This book is available for download with iBooks on your Mac or iOS device, and with iTunes on your computer. Books can be read with iBooks on your Mac or iOS device.
The response to Nancy Pearl's surprise bestseller Book Lust was astounding: the Seattle librarian even became the model for the now-famous Librarian Action Figure. Readers everywhere welcomed Pearl's encyclopedic but discerning filter on books worth reading, and her Rule of 50 (give a book 50 pages before deciding whether to continue; but readers over 50 must read the same number of pages as their age) became a standard MO.
From Publishers Weekly
© Publishers Weekly
- $9.99
- Category: Literary Criticism
- Published: Apr 12, 2005
- Publisher: Sasquatch Books
- Seller: Penguin Random House LLC
- Print Length: 304 Pages
- Language: English


text:
Glenn Greenwald: Regardless of Trump, Journalists Must Do Their Homework and Investigate Clinton
It Takes a Ruling-Class Village to Staff the White House
Football Player Colin Kaepernick Refuses to Stand for the National Anthem Until This Country Changes
Why Hillary Clinton Republicans Matter
'On Contact' With Chris Hedges: Halfway to Freedom With Stanley Cohen
By Ogi Ogas (Author), Sai Gaddam (Author)
AP / Majdi Mohammed
A boycott of goods produced in Israeli settlements in the West Bank gained some heft Saturday when Palestinian President Mahmoud Abbas threw his executive weight behind the campaign, calling on all Palestinians to stop buying settlement-made products.
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text:
"The big stadium and turf field was really exciting. I had never been in a stadium that big before. Running out, I kind of felt like I was in the NFL for the minute," Justin Anderson said.
A pre-game pep talk from an Army General had the Ocilla standout ready to charge the Alamo Dome with a vengeance, but things didn't go quite as he planned.
"I was ready to play from the beginning. A General came in and talked about the people over there fighting for us and that made me just want to go out there and play even more. The first half I was kind of upset though because I didn't play none but I guess I got a little mad in the 2nd half and I came out and just got after it."
Get after it he did. Anderson dominated in the 2nd half helping to open huge running lanes for Ohio State commit Chris Wells that lead to numerous scores in the closing period and helped the East build up a commanding lead.
"Chris Wells is a really good running back and when we started the running the ball I just felt I had to do a little more and go right at them. That's what I know how to do best."
Justin entered the week in San Antonio knowing that he had to improve his pass blocking and he feels as if he's done just that.
"On our team we don't pass block that much and I learned a lot out there with that. I know how to use my feet a little better now as well as my hands. I also can come off the ball a quicker."
Who are Anderson's picks for best OL and DL at the Army Bowl?
"I thought Justin Boren was the best OL. He's really strong. He bench presses 500lbs and he knows how to use it. As for defensive line, I was really impressed with Robert Rose. He's so quick and fast."
If he didn't come away with anything else, Bean says he came away with a sense of pride for the people he played in honor of last Saturday afternoon.
"Well, all the events that we did and just representing the Army was the biggest thing I was proud of. I couldn't have done that anywhere else."
Bean Talks Army Bowl
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новости на русском
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Ecology Ministry says no agreements reached on redirecting course of River Araz
20 November 2012 [18:34] -
There are no agreements on redirecting the course of the River Araz to Lake Urmia, the Azerbaijani Deputy Minister of Environment and Natural Resources Firdovsi Aliyev said on Tuesday.
Azerbaijan itself suffers from a lack of water and in this regard the government acts on the basis of national interests.
"Azerbaijan has joined a number of international conventions in the environmental field and in this issue the country will act according to the requirements of these conventions. Since this is a political issue, the Ministry of Ecology and Natural Resources passed its proposals to the Azerbaijani Foreign Ministry," the deputy minister said.
The use of the waters of the River Araz to fill the shrinking Lake Urmia in Iran will have a negative impact on the environment of Azerbaijan, " the chairman of the State Committee of Land and Cartography Garib Mammadov told Trend on Tuesday.
Changing the course of the River Araz cannot be a topic for discussion, he said. It will negatively affect the areas along the river both from an environmental and agricultural point of view.
"Azerbaijan's water reserves are scarce, so a complete change of water course or reduction will significantly affect the regions located along the river" Garibov said.
Azerbaijan's position on this issue is clear and concrete, he said.
In 2010, during a visit of Iranian President Mahmoud Ahmadinejad and members of the government to Tabriz, the project on directing 600 million cubic meters of water from the River Araz into Lake Urmia was approved. Allocation of some $1.2 billion was planned for this project. In September 2011, the Iranian government allocated $ 900 million for this purpose.
The United Nations Development Programme (UNDP) has allocated $ 135 million to Iran to address environmental issues of the shoaling Lake Urmia.
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This step is noncompulsory but will drastically multiply your chances of receiving views from other daters on the site. Type a little about yourself, your interests and attach any nice photographs of yourself.
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- New custody law for equal time for dads begins today; some question law's relevance (8/28/16)5
- Ex-Southeast student gets probation for placing homemade sex video on porn site without woman's knowledge (8/24/16)13
- Marble Hill fires entire sewer department (8/23/16)5
- Bootheel lawmaker seeks probe into crop damage by illegal herbicide spraying (8/24/16)1
- Former alt-rock frontwoman tells how she found Christianity (8/29/16)2
- Jackson girl stays planted on the farm (8/28/16)2
- Schnucks bans solicitors, including organizations like Salvation Army (8/24/16)39
- Newsmakers 2016: Liz Glastetter (8/15/16)
- Court ruling, state suggest businesses may apply use, sales tax to deliveries (8/24/16)2
- Scott City School District introduces new preschool program (8/26/16)1
Repeal Obamacare monstrosity
Is it a "tax" or is it a "penalty"? Is that really the question everybody should be torn up about? We could call it a "forced donation." The money for Obamacare still comes from taxpayers. The bottom line is we cannot afford another government entitlement program, which is exactly what Obamacare is. We have already spent astronomical amounts of money to set the Obamacare bureaucracy in place and nobody's health care has improved. Government pocketbooks have grown and the taxpayer pocketbooks have shrunk. Common sense will tell people that Obamacare will not bring down costs. Common sense will tell people that rationing by bureaucrats in D.C. will be the way of the future.
The Supreme Court has let us down. Congress has let us down. We the people must get involved to stop this gigantic overreach by our government. Please call your representatives and tell them to repeal this monstrosity and start over with common-sense reforms. Don't expect Congress to do the right thing. They need to hear from all of us.
LINDA REUTZEL, Cape Girardeau


text:
Special AI flights bring back stranded passengers from Leh
New Delhi: Air India today operated three
special flights from Delhi to Leh bringing back 331 passengers
stranded there after the Friday`s cloudburst that left 145
people dead and over 500 missing.
"We operated three special flights on Delhi-Leh-Delhi
sector today and flew back 331 passengers from Leh who were
stranded there due to cloudburst," an Air India spokesperson
The Airline charged a single special fare of Rs 9000
instead of regular fare of Rs 11,661 from the passengers, he
said. The flights had left Leh at 7.50, 11.05 and 11.40 this
Air India has decided to operate four special flights on
Delhi-Leh-Delhi sector tomorrow, and one each additional
flight on Jammu-Leh-Jammu sector and Srinagar-Leh-Srinagar
The flights will leave for Delhi at 5.25am, 5.30am,
8.15am and 9.15am tomorrow and the fare will be Rs 9000 only,
the spokesperson said.
Since the tragedy, Air India has operated six special
flights from Leh out of which five were on Delhi-Leh-Delhi
sector and one on Jammu-Leh-Jammu sector and flew back a total
number of 553 passengers to Delhi and 103 passengers to Jammu.
Yesterday, the airline had deployed two Airbus 320
aircraft to bring passengers from Leh to Delhi and one from
Leh to Jammu.
The Civil Aviation ministry had yesterday asked Air
India, Jet airways and Kingfisher airlines to operate three
flights each to bring back the stranded passengers for today.
The Ministry had also asked them not to charge exorbitant
fare following the complaint from the air travellers.
The Kingfisher airline today operated two flights from
Leh to Delhi and brought back 290 tourists.
"We operated today one scheduled flight and an additional
flight to bring back the tourists. We deployed Airbus 320
aircraft with a capacity of 175 seats but due to load penalty
we could only accommodate 145 passengers in each flights," a
Kingfisher spokesperson said.
Load Penalty is the restrictions followed by the airlines
which operate to Leh airport to carry a certain amount of load
including the passengers and baggages as the airport is
situated at high altitude and does not have a long runway.
Meanwhile, Kingfisher will operate four of its flights --
one scheduled and three additional -- from Leh to Delhi
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text:
|By Business Wire
Article Rating:
|January 31, 2013 09:00 AM EST
Immersion Corporation (Nasdaq:IMMR), the leading developer and licensor of touch feedback technology, today announced that its tactile feedback technology has been incorporated into the gamepad controller for the Razer Edge tablet. The Razer Edge swept every CNET 2013 award for which it was nominated at the recent Consumer Electronics Show: "Best of Show," "People's Voice" (as voted by the CNET audience), and "Gaming."
"As gaming platforms become mobile, we know the gaming community won't compromise on the quality and experience they have come to expect from consoles," explains Robert Lacroix, vice president of engineering at Immersion. "Immersion's tactile effects provide high-quality feedback in hundreds of millions of controllers for PC and console games. The Razer Edge's thoughtful design delivers the power to enjoy the most advanced PC games at full capacity, and ensures the mobile experience will be as immersive as a home console."
By using a Windows 8 operating system with Intel architecture, the Razer Edge ensures that the broadest array of today's most popular PC games will run natively on it without the need to be ported, optimized, or developed anew. By incorporating Immersion's tactile effects for its gamepad controller, the tablet creates an immersive gaming experience while in mobile console mode.
"We used a crowdsourcing approach to develop the Razer Edge, ensuring we delivered all the power and capabilities gamers expect from a mobile platform," explains Min-Liang Tan, Razer co-founder, CEO, and creative director. "That thinking extends to the unprecedented power and striking visual design of the Razer Edge, as well as to the audio and tactile experience. The tactile effects incorporated into the Razer Edge gamepad controller make mobile gaming more lifelike and engrossing."
The Razer Edge will be available in Q1, 2013.
About the Razer Edge
It's a tablet. It's a PC. It's a console. It's all of the above: a full-feature PC and the most powerful tablet in the world. What's more, it has four modes specially designed for gamers and is able to run all PC games and applications. PC gamers helped design the most powerful tablet in the world today, the only system of its kind utilizing technology from both Intel and NVIDIA. Powerful 3rd generation Intel® Core processors will help ensure even the most advanced PC games will function at full capacity, and the NVIDIA GeForce graphics will offer striking visual clarity – a first for tablet gaming and a godsend for the world's 300 million-plus PC gamers.
For more information about The Razer Edge, please visit http://www.razerzone.com/EdgePro.
About Immersion (www.immersion.com)
Founded in 1993, Immersion (NASDAQ: IMMR) is the leading innovator in haptic technology; the company's touch feedback solutions deliver a more compelling sense of the digital world. Using Immersion's high-fidelity haptic systems, partners can transform user experiences with unique and customizable touch feedback effects; excite the senses in games, videos and music; restore "mechanical" feel by providing intuitive and unmistakable confirmation; improve safety by overcoming distractions while driving or performing a medical procedure; and expand usability when audio and visual feedback are ineffective. Immersion's TouchSense technology provides haptics in mobile phone, automotive, gaming, medical and consumer electronics products from world-class companies. With over 1,300 issued or pending patents in the U.S. and other countries, Immersion helps bring the digital universe to life. Hear what we have to say at blog.immersion.com.
Razer™ is the world leader in high-performance gaming hardware. Founded in 1998, with its headquarters in Carlsbad, California, the company has offices in nine cities around the globe. Used by the most demanding professional gamers who compete in global tournaments. Razer provides gamers with the unfair advantage of cutting-edge technology and award-winning design. We live by our motto: For Gamers. By Gamers. ™
Forward-looking Statements
This press release contains "forward-looking statements" that involve risks and uncertainties, as well as assumptions that, if they never materialize or prove incorrect, could cause the results of Immersion Corporation and its consolidated subsidiaries to differ materially from those expressed or implied by such forward-looking statements.
All statements, other than the statements of historical fact, are statements that may be deemed forward-looking statements, including, but not limited to, statements regarding features and performance of the Razer Edge, as well as the statement that the Razer Edge will be available in Q1, 2013.
Immersion's actual results might differ materially from those stated or implied by such forward-looking statements due to risks and uncertainties associated with Immersion's business, which include, but are not limited to: unanticipated difficulties and challenges encountered in product development efforts by Immersion and its licensees; unanticipated difficulties and challenges that may affect the timing of the Razer Edge's launch; adverse outcomes in any future intellectual property-related litigation and the costs related thereto; the effects of the current macroeconomic climate; delay in or failure to achieve commercial demand for Immersion's products or third party products incorporating Immersion's technologies; and a delay in or failure to achieve the acceptance of force feedback as a critical user experience. Many of these risks and uncertainties are beyond the control of Immersion.
For a more detailed discussion of these factors, and other factors that could cause actual results to vary materially, interested parties should review the risk factors listed in Immersion's most current Form 10-Q, which is on file with the U.S. Securities and Exchange Commission. The forward-looking statements in this press release reflect Immersion's beliefs and predictions as of the date of this release. Immersion disclaims any obligation to update these forward-looking statements as a result of financial, business, or any other developments occurring after the date of this release.
The use of the word "partner" or "partnership" in this press release does not mean a legal partner or legal partnership.
Immersion, the Immersion logo, TouchSense and HD Haptics and Integrator are trademarks of Immersion Corporation in the United States and other countries. All other trademarks are the property of their respective owners.
SYS-CON Events announced today that eCube Systems, a leading provider of middleware modernization, integration, and management solutions, will exhibit at @DevOpsSummit at 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. eCube Systems offers a family of middleware evolution products and services that maximize return on technology investment by leveraging existing technical equity to meet evolving business needs. ...
Aug. 25, 2016 09:00 AM EDT Reads: 440
Announcing @TelecomReseller Named "Media Sponsor" of @CloudExpo Silicon Valley | #IoT #Cloud #BigData
SYS-CON Events announced today Telecom Reseller has been named "Media Sponsor" of SYS-CON's 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Telecom Reseller reports on Unified Communications, UCaaS, BPaaS for enterprise and SMBs. They report extensively on both customer premises based solutions such as IP-PBX as well as cloud based and hosted platforms.
Aug. 25, 2016 09:00 AM EDT Reads: 528
The 19th International Cloud Expo has announced that its Call for Papers is open. Cloud Expo, to be held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, brings together Cloud Computing, Big Data, Internet of Things, DevOps, Digital Transformation, Microservices and WebRTC to one location. With cloud computing driving a higher percentage of enterprise IT budgets every year, it becomes increasingly important to plant your flag in this fast-expanding business opportuni...
Aug. 25, 2016 09:00 AM EDT Reads: 3,856
Pulzze Systems was happy to participate in such a premier event and thankful to be receiving the winning investment and global network support from G-Startup Worldwide. It is an exciting time for Pulzze to showcase the effectiveness of innovative technologies and enable them to make the world smarter and better. The reputable contest is held to identify promising startups around the globe that are assured to change the world through their innovative products and disruptive technologies. There w...
Aug. 25, 2016 08:30 AM EDT Reads: 392
Is the ongoing quest for agility in the data center forcing you to evaluate how to be a part of infrastructure automation efforts? As organizations evolve toward bimodal IT operations, they are embracing new service delivery models and leveraging virtualization to increase infrastructure agility. Therefore, the network must evolve in parallel to become equally agile. Read this essential piece of Gartner research for recommendations on achieving greater agility.
Aug. 25, 2016 08:30 AM EDT Reads: 505
Data is the fuel that drives the machine learning algorithmic engines and ultimately provides the business value. In his session at Cloud Expo, Ed Featherston, a director and senior enterprise architect at Collaborative Consulting, will discuss the key considerations around quality, volume, timeliness, and pedigree that must be dealt with in order to properly fuel that engine.
Aug. 25, 2016 08:30 AM EDT Reads: 1,685
To leverage Continuous Delivery, enterprises must consider impacts that span functional silos, as well as applications that touch older, slower moving components. Managing the many dependencies can cause slowdowns. See how to achieve continuous delivery in the enterprise.
Aug. 25, 2016 08:15 AM EDT Reads: 1,475
Enterprises have forever faced challenges surrounding the sharing of their intellectual property. Emerging cloud adoption has made it more compelling for enterprises to digitize their content, making them available over a wide variety of devices across the Internet. In his session at 19th Cloud Expo, Santosh Ahuja, Director of Architecture at Impiger Technologies, will introduce various mechanisms provided by cloud service providers today to manage and share digital content in a secure manner....
Aug. 25, 2016 08:00 AM EDT Reads: 495
Using new techniques of information modeling, indexing, and processing, new cloud-based systems can support cloud-based workloads previously not possible for high-throughput insurance, banking, and case-based applications. In his session at 18th Cloud Expo, John Newton, CTO, Founder and Chairman of Alfresco, described how to scale cloud-based content management repositories to store, manage, and retrieve billions of documents and related information with fast and linear scalability. He addres...
Aug. 25, 2016 07:15 AM EDT Reads: 1,866
Aspose.Total for .NET is the most complete package of all file format APIs for .NET as offered by Aspose. It empowers developers to create, edit, render, print and convert between a wide range of popular document formats within any .NET, C#, ASP.NET and VB.NET applications. Aspose compiles all .NET APIs on a daily basis to ensure that it contains the most up to date versions of each of Aspose .NET APIs. If a new .NET API or a new version of existing APIs is released during the subscription peri...
Aug. 25, 2016 06:30 AM EDT Reads: 1,824
Akana has announced the availability of version 8 of its API Management solution. The Akana Platform provides an end-to-end API Management solution for designing, implementing, securing, managing, monitoring, and publishing APIs. It is available as a SaaS platform, on-premises, and as a hybrid deployment. Version 8 introduces a lot of new functionality, all aimed at offering customers the richest API Management capabilities in a way that is easier than ever for API and app developers to use.
Aug. 25, 2016 06:00 AM EDT Reads: 1,419
SYS-CON Events announced today that Isomorphic Software will exhibit at DevOps Summit at 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Isomorphic Software provides the SmartClient HTML5/AJAX platform, the most advanced technology for building rich, cutting-edge enterprise web applications for desktop and mobile. SmartClient combines the productivity and performance of traditional desktop software with the simp...
Aug. 25, 2016 03:30 AM EDT Reads: 2,123
DevOps at Cloud Expo, taking place Nov 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, is co-located with 19th Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world. The widespread success of cloud computing is driving the DevOps revolution in enterprise IT. Now as never before, development teams must communicate and collaborate in a dynamic, 24/7/365 environment. There is no time to wait for long dev...
Aug. 25, 2016 02:30 AM EDT Reads: 2,148
Personalization has long been the holy grail of marketing. Simply stated, communicate the most relevant offer to the right person and you will increase sales. To achieve this, you must understand the individual. Consequently, digital marketers developed many ways to gather and leverage customer information to deliver targeted experiences. In his session at @ThingsExpo, Lou Casal, Founder and Principal Consultant at Practicala, discussed how the Internet of Things (IoT) has accelerated our abil...
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SYS-CON Events announced today that 910Telecom will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Housed in the classic Denver Gas & Electric Building, 910 15th St., 910Telecom is a carrier-neutral telecom hotel located in the heart of Denver. Adjacent to CenturyLink, AT&T, and Denver Main, 910Telecom offers connectivity to all major carriers, Internet service providers, Internet backbones and ...
Aug. 25, 2016 02:00 AM EDT Reads: 1,786
With so much going on in this space you could be forgiven for thinking you were always working with yesterday's technologies. So much change, so quickly. What do you do if you have to build a solution from the ground up that is expected to live in the field for at least 5-10 years? This is the challenge we faced when we looked to refresh our existing 10-year-old custom hardware stack to measure the fullness of trash cans and compactors.
Aug. 25, 2016 01:15 AM EDT Reads: 1,613
Extreme Computing is the ability to leverage highly performant infrastructure and software to accelerate Big Data, machine learning, HPC, and Enterprise applications. High IOPS Storage, low-latency networks, in-memory databases, GPUs and other parallel accelerators are being used to achieve faster results and help businesses make better decisions. In his session at 18th Cloud Expo, Michael O'Neill, Strategic Business Development at NVIDIA, focused on some of the unique ways extreme computing is...
Aug. 25, 2016 01:00 AM EDT Reads: 1,982
The emerging Internet of Everything creates tremendous new opportunities for customer engagement and business model innovation. However, enterprises must overcome a number of critical challenges to bring these new solutions to market. In his session at @ThingsExpo, Michael Martin, CTO/CIO at nfrastructure, outlined these key challenges and recommended approaches for overcoming them to achieve speed and agility in the design, development and implementation of Internet of Everything solutions wi...
Aug. 25, 2016 12:45 AM EDT Reads: 1,910
With over 720 million Internet users and 40–50% CAGR, the Chinese Cloud Computing market has been booming. When talking about cloud computing, what are the Chinese users of cloud thinking about? What is the most powerful force that can push them to make the buying decision? How to tap into them? In his session at 18th Cloud Expo, Yu Hao, CEO and co-founder of SpeedyCloud, answered these questions and discussed the results of SpeedyCloud's survey.
Aug. 25, 2016 12:30 AM EDT Reads: 2,083
19th Cloud Expo, taking place November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, will feature technical sessions from a rock star conference faculty and the leading industry players in the world. Cloud computing is now being embraced by a majority of enterprises of all sizes. Yesterday's debate about public vs. private has transformed into the reality of hybrid cloud: a recent survey shows that 74% of enterprises have a hybrid cloud strategy. Meanwhile, 94% of enterpri...
Aug. 25, 2016 12:00 AM EDT Reads: 2,983


text:
Like losing a member of any close family, the Park girls' hockey team was shocked and saddened to hear senior captain and Division-I bound defenseman Anna Keys would miss the entire season because of injury.
Keys suffered a severe knee injury in September during a Wolfpack soccer game. The three-sport athlete, who also plays golf, underwent surgery to replace her ACL and repair her MCL.
Fellow captain Emma Waller remembered hearing the news.
"The team didn't know how to take it," Waller said. "She is a strong player, and I know that a lot of us were pretty nervous, because, as a team, we are like a family and having Anna not on the ice with us was a struggle."
Coach Steve Morse echoed Waller's memory. He believes the team has responded well together. After all, there's nothing they can do about it except go out and play the game.
"At first, some of the reactions around the room were 'What are we going to do?' " Morse said. "And the answer is 'We're going to go play and we're not going to feel sorry for ourselves.' The girls have gone about it with a good attitude."
Keys' rehab is progressing well. She had surgery about eight weeks ago and just recently ditched her crutches. She's trying to re-learn how to walk and strengthen her muscles once again.
"It was definitely a tough first couple weeks knowing that I couldn't play my senior year," said Keys, who hopes she can be ready to play golf for the Wolfpack in the spring. "But I started to realize that everything happens for a reason and it gives me a chance to see the game in a different way and learn even more."
Keys is going to make the most of her situation. Outside of her physical therapy sessions, she has remained committed to the Park girls' hockey team since the beginning of tryouts. She carries her helmet around and will be on the bench for games.
"She's going to be everywhere except on the ice," Morse said. "She'll help us on the bench. It may even help her as a player to be on the bench."
Fortunately, Minnesota State University has honored its commitment to Keys. She signed her national letter of intent Wednesday and should be ready to go as a freshman next season.
But what now for the Wolfpack hockey team?
Losing Keys changes the team dynamics. Park still has four returning defensemen, none of whom are seniors. They are young and experienced.
Meg Ackerman brings scoring touch from the back end. Alyssa Wickenhouser, Dani Perry and Sam Anderson return with important varsity experience. Megan Palmquist will join the defensive core this year. Waller and co-captain Paige Hill should provide key leadership.
Park's strong goaltending of recent years should continue with Paige Press, who transferred from East Ridge. Due to Minnesota State High School League rules, she played junior varsity for the Wolfpack last year. She'll start this season as a junior. Press played varsity for two years at East Ridge. Freshman Bryce Boreen is an up and coming talent in waiting.
Waller knows it will take everyone to pick up the slack, but believes that they can handle it together.
"If any of my teammates were gone, just like Anna, it would hurt," Waller said. "It will take the whole team to step up and get used to."
Keys is showing strong confidence in her squad as the season gets underway.
"There is no doubt in my mind that the team can play well, with or without me," she said.
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FZ150 AVCHD playback on HDTV
Started Mar 13, 2014 | Discussions thread
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wjansen • Contributing Member • Posts: 660
FZ150 AVCHD playback on HDTV
Mar 13, 2014
How can I play back AVCHD movies from my FZ150 to my HDTV? Playback is fine on the LCD screen on the camera back, but when I try connecting to my HDTV via my mini HDMI to regular HDMI, I'm not getting any playback on the HDTV. When connecting the mini plug to the camera, the display says to choose between PictBridge (PTP) and PC. Seems like the camera only wants to be connected to a PC or printer. It won't play back a movie at all--only asks for this choice. Maybe I have to save the movie to a PC and then back to the HDTV? Thanks for any help.
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With Galleries La Fayette you cant go wrong. The quality of food is excellent, service is good. Though when the restaurant is really busy service can be slow, however variety of food is top notch!
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With Galleries La Fayette you cant go wrong. The quality of food is excellent, service is good. Though when the restaurant is really busy service can be slow, however variety of food is top notch!
I visit this restaurant very often lately they have improved very much since a while back when I would walk through and walk out as it didn't used to look great .they have an excellent brunch on Friday with good food very reasonable price .they sometimes have seasonal activities for children. I put my kids to play in let petite... 更多
The food is just average and the service is always always slow, they always seem to be overwhelmed. The reason why we choose it is because of the play area for the kids while we eat and some shopping in the mall. We like the venue and the light that floods through from the skylights but unfortunately the food and... 更多
I have never been disappointed with the quality of the food. The service, however, left much to be desired. The waiter failed to communicate "medium rare" to the cook and the meat was served thoroughly over-cooked. He pushed the bottle of water in our direction without actually serving us and our food was served 15 minutes apart. By the time... 更多
We ordered a morroccan plate and a thai curry for my husband and myself. He said the plates cannot come at the same time!!!! We told the waiter we are coming to eat together. His explanation was the tagine plate takes longer so I told him to hold from making the curry till the tagine is ready. I received a... 更多
If you can't decide whether to have some sushi, pasta or steak, this is the place to go! It was my mom-in-law's birthday yesterday and I wanted to have some pasta, but my mom wants some steak and my in law wants to have some Asian food, so I opted Galleries Lafayette, and it didn't disappoint us. Both my mom... 更多
Are here on a non busy mall day, ordered 3 or 4 dishes from the tapas menu. Cod and beef tenderloin were great. Service was very slow, be aware
a wide variety of spanish Tapas and Paellas along with its spanish food retail, Andalus Gourmet, unique point of sales... 更多
In the middle of galeries Lafayette noisy atmosphere but nice for a quick eat. Price reasonable. Chef came to our... 更多
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The mutant crossover of the century,
This review is from: X-Men: Messiah Complex TPB (Paperback)
After M-Day, the world's population of mutants went from the millions to barely numbering in the hundreds, and instead of the usual credo of fighting to protect a world that hates and fears them, all the X-Men are focused on right now is the simple survival of their species. Messiah Complex tells of the first mutant to appear since M-Day and despite being just a baby, is the prize of everyone who wants to see the mutant race continue or be destroyed forever.
Messiah Complex is a great book, a crossover event that features the X-Men, New X-Men, Xavier, Cable, X-Factor Investigations, Sinister and the Marauders, the Purifiers and Predator X, and it perfectly captures the desperation of all factions as they struggle for control of the child that could be the salvation of the dying mutant race. To do this whilst keeping the action flowing and the lulls in combat tense, is a great feat of art and story telling, and the story spans from the present to possible futures to illustrate the high stakes.
After cleaning up the X-Men universe of all the surplus mutants, Messiah Complex reignites the frantic pace of the mutant race just trying to survive in a world that becomes increasingly harder to live in. This is a great product for all X-Men fans, it brings the series back to its roots and with countless cameos, it is a great read.
I highly recommend.
Review Details
(26 customer reviews)
�22.50 �18.29
Top Reviewer Ranking: 84,781


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Carl Cort says he won't shy away from another penalty kick
GEORGETOWN, Guyana, CMC-The striker who squandered a penalty that cost Guyana their world cup qualifier against El Salvador last week says he would not shy away from a chance to shoot from that spot again.
Carl Cort's feeble penalty was saved by Dagoberto Portillo allowing Guyana to suffer a 3-2 defeat at the hands of El Salvador at the national stadium.
The Golden Jaguars came back twice to draw with El Salvador when the two teams met in the first leg in San Salvador a few days earlier.
"I can tell you though if the situation came about again I wouldn't shy away from it" said Cort in an interview at his Florida based, North American Soccer League (NASL) Club, Tampa Bay Rowdies.
"I wish I could go back in time and retake the penalty but that just isn't going to happen. There's several moments in every athletes career where a situations arises like that, sometimes you succeed sometimes you don't".
Guyana's chances of advancing further into the FIFA 2014 World Cup suffered a crushing blow as a result of their loss to the Salvadorans.
Cort was the play maker for Guyana's two goals with his through ball that allowed Gregory Richardson to open the scoring and later his deflected header to Chris Nurse leading to an equalizer.
"For me personally missing the penalty doesn't take away the way I felt about my performance. I wouldn't say the two assists gave me consolation for the penalty miss. I just see it as three separate major moments of the match" said the experienced 34-year front man who has played in the English Premier League and the England Under 21s in a career that started in 1996.
"It's funny because the way some of the public look at it is in black and white. If I scored the penalty I walk off that field a hero. Even with 2 assists and a good performance because I missed the penalty I am now a villain".
Guyana, currently third in group B standings, need to beat Mexico on October 12th to keep their chances alive.
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06/23/2009Provided by Citysearch -
I was at Joe Tecce's for a company holiday party in December 2005. It must have been just before the renovation. While, the party was lovely and the passed Hors D'voures tasty I didnt truly get to experience Joe Tecce's since the menu was already selected for us. I returned this past Friday and to my surprise, the restaurant had outdoor dining, a great roomy bar and a warm inviting italian menu. I was impressed with everyone I met from the valet attendant to the bartender and our waitress. I will most certainly be back to Joe Tecce's sooner rather than later. People should definelty consider this as a pre or post event meal if you have a Celtics or Bruins game or concert at the Garden!


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Shopping experience has been great. Just don't know if will need something else from store.
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Very quick to reply to International customer! Thanks
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Super easy and fast!
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It was wonderful like lots of your items, I no friends and family will ask where i got this item and i will let them no. I am excited to recieve my mask, Thank You
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This cite is awesome and sell very original and authentic merchandise! My wife and I love it!
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I found what I was looking for at a decent price. The fact they paid for shipping was nice, but it was more important to get a tiki that looked like what I thought it would. The one I received certainly did look like what I wanted. It's going to look great in my office.
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A classic Disney fairytale collides with modern-day New York City. In this story, an animated princess is sent into the real world by an evil queen, where she meets a handsome lawyer. Can a storybook view of romance survive in the real world?


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NAB 2016: GRASS VALLEY, CA — AJA (www.aja.com) will make several important announcements at this year's NAB show in Las Vegas, including updates to its Kona and Io products.
April 12, 2016
CHICAGO – SIGGRAPH 2016 has announced the winners — and highlights — of the 43rd annual Computer Animation Festival.
July 8, 2016
GPU Technology Conference 2016 -- NVIDIA CEO Jen-Hsun Huang showed how the company's Iray technology can create interactive virtual worlds with unparalleled fidelity.
Artomatix has developed AI capable of texturing vast terrains in open 3-D worlds in a realistic, non-repetitive way – and fast.