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|By Marketwired .
Article Rating:
|January 28, 2013 05:00 PM EST
WINNIPEG, MANITOBA -- (Marketwire) -- 01/28/13 -- Medicure Inc. ("Medicure" or the "Company") (TSX VENTURE:MPH)(PINKSHEETS:MCUJF), a specialty pharmaceutical company, today reported its results from operations for the quarter ended November 30, 2012.
Financial Results
Total net revenue for the three months ended November 30, 2012 was $721,000 compared to $2.2 million for the three months ended November 30, 2011 and $667,000 for the previous quarter ended August 31, 2012. Net revenue from the sale of AGGRASTAT finished product for the three months ended November 30, 2012 was $721,000 compared to $792,000 for the same quarter last year and $667,000 for the previous quarter ended August 31, 2012. The decrease in total revenues compared to the same quarter last year relates to a $1.5 million one-time sale of unfinished AGGRASTAT in the previous year. Sales of AGGRASTAT finished product were consistent with the same period in the prior year and the previous quarter.
Net loss for the quarter was $493,000 or $0.04 per share, compared to net income of $1.1 million or $0.09 per share in the same quarter a year ago and a net loss of $297,000 or $0.02 for the previous quarter. The net income in the previous year quarter primarily relates to a $1.5 million sale of unfinished AGGRASTAT.
At November 30, 2012, the Company had cash totalling $248,000 compared to $1.1 million as of May 31, 2012. Cash flows used in operating activities for the three months ended November 30, 2012 were $178,000, compared to cash flows from operating activities of $1.3 million for the three months ended November 30, 2011. The change in cash from/used in operating activities primarily results from the sale of unfinished AGGRASTAT in the prior year's quarter described above.
Corporate Developments
On November 1, 2012, the Company announced that it completed a consolidation of the Company's common shares ("Common Shares") on the basis of fifteen pre-consolidation Common Shares for each one post consolidation Common Share. Effective with the opening of markets on November 2, 2012, the Company's Common Share's began trading on a consolidated basis.
Product Developments
The primary ongoing research and development activity is the development and implementation of a new regulatory, brand and life cycle management strategy for AGGRASTAT.
On January 8, 2013, the Company announced that it has filed a supplemental new drug application (sNDA) for the high dose bolus (HDB) dosing regimen of AGGRASTAT. The Company also announced that it will receive up to $200,000 in grant funding from the Province of Manitoba Commercialization Support for Business (CSB) Program to complete a renal study evaluating the AGGRASTAT HDB regimen in patients with impaired kidney function. The results of this study will be submitted to the FDA separately to guide appropriate dosing recommendations for the HDB regimen in patients with impaired kidney function.
On September 26, 2012 the Company announced the development of a transdermal delivery formulation of AGGRASTAT's active ingredient, tirofiban. In vivo proof of principle for the transdermal delivery of therapeutic levels of tirofiban was recently established in animal studies conducted in collaboration with 4P Therapeutics, Inc. (Alpharetta, GA). 4P Therapeutics, a world leader in the research and development of novel transdermal products, has entered into an agreement with the Company's subsidiary, Medicure International, Inc., to further develop transdermal tirofiban.
As previously announced, the Company is currently conducting a 600 patient clinical trial of AGGRASTAT entitled "Shortened Aggrastat Versus Integrilin in Percutaneous Coronary Intervention" (SAVI-PCI). The study is evaluating a contemporary dosage regimen that is outside of the product's current prescribing information.
The Company's primary, non-AGGRASTAT research and development activity is TARDOXAL(TM) for the treatment of Tardive Dyskinesia (TD). The Company is currently awaiting interim results from the Phase II clinical study of TARDOXAL, entitled Tardoxal for the Treatment of Tardive Dyskinesia (TEND-TD).
The Company's ability to continue in operation for the foreseeable future remains dependent upon the effective execution of its business development and strategic plans.
All amounts referenced herein are in Canadian dollars unless otherwise noted.
About AGGRASTAT
AGGRASTAT (tirofiban HCl), in combination with heparin, is indicated for the treatment of acute coronary syndrome, including patients who are to be managed medically and those undergoing PTCA or atherectomy. In this setting, AGGRASTAT has been shown to decrease the rate of a combined endpoint of death, new myocardial infarction or refractory ischemia/repeat cardiac procedure. AGGRASTAT has been studied in a setting that included aspirin and heparin.
Bleeding is the most common complication encountered during therapy with AGGRASTAT. Administration of AGGRASTAT is associated with an increase in bleeding events classified as both major and minor bleeding events by criteria developed by the Thrombolysis in Myocardial Infarction Study group (TIMI). Most major bleeding associated with AGGRASTAT occurs at the arterial access site for cardiac catheterization. Fatal bleedings have been reported. AGGRASTAT should be used with caution in patients with platelet count less than 150,000/mm3, in patients with hemorrhagic retinopathy, and in chronic hemodialysis patients. Because AGGRASTAT inhibits platelet aggregation, caution should be employed when it is used with other drugs that affect hemostasis. The safety of AGGRASTAT when used in combination with thrombolytic agents has not been established. During therapy with AGGRASTAT, patients should be monitored for potential bleeding. When bleeding cannot be controlled with pressure, infusion of AGGRASTAT and heparin should be discontinued.
AGGRASTAT is a parenteral non-peptide, reversible GP IIb/IIIa receptor antagonist that is marketed in the United States by Medicure Pharma, Inc. Please see the AGGRASTAT Prescribing Information for approved indications, dosage regimens and safety related information. The AGGRASTAT dosing regimen and the treatment setting studied in the SAVI-PCI study have not been approved by the FDA.
About Medicure Inc.
Medicure is a specialty pharmaceutical company focused on the development and commercialization of novel small molecule therapeutics. The primary focus of the Company and its subsidiaries is the marketing and distribution of AGGRASTAT (tirofiban HCl) for acute coronary syndromes in the United States, where it is sold through the Company's US subsidiary, Medicure Pharma, Inc. For more information on Medicure please visit www.medicure.com.
To be added to Medicure's e-mail list, please visit: http://www.medicure.com/news.html
Forward Looking Information: Statements contained in this press release that are not statements of historical fact, including, without limitation, statements containing the words "believes", "may", "plans", "will", "estimates", "continues", "anticipates", "intends", "expects" and similar expressions, may constitute "forward-looking information" within the meaning of applicable Canadian and U.S. federal securities laws (such forward-looking information and forward-looking statements are hereinafter collectively referred to as "forward-looking statements"). Forward-looking statements are based on the current assumptions, estimates, analysis and opinions of management of the Company made in light of its experience and its perception of trends, current conditions and expected developments, as well as other factors which the Company believes to be relevant and reasonable in the circumstances. Inherent in forward-looking statements are known and unknown risks, uncertainties and other factors beyond the Company's ability to predict or control that may cause the actual results, events or developments to be materially different from any future results, events or developments expressed or implied by such forward-looking statements, and as such, readers are cautioned not to place undue reliance on forward-looking statements. Such risk factors include, among others, the Company's future product revenues, stage of development, additional capital requirements, risks associated with the completion and timing of clinical trials and obtaining regulatory approval to market the Company's products, the ability to protect its intellectual property, dependence upon collaborative partners, changes in government regulation or regulatory approval processes, and rapid technological change in the industry.
Such statements are based on a number of assumptions which may prove to be incorrect, including, but not limited to, assumptions about: general business and economic conditions; the impact of changes in Canadian-US dollar and other foreign exchange rates on the Company's revenues, costs and results; the timing of the receipt of regulatory and governmental approvals for the Company's research and development projects; the availability of financing for the Company's commercial operations and/or research and development projects, or the availability of financing on reasonable terms; results of current and future clinical trials; the uncertainties associated with the acceptance and demand for new products and market competition. The foregoing list of important factors and assumptions is not exhaustive. The Company undertakes no obligation to update publicly or otherwise revise any forward-looking statements or the foregoing list of factors, other than as may be required by applicable legislation. Additional discussion regarding the risks and uncertainties relating to the Company and its business can be found in the Company's other filings with the applicable Canadian securities regulatory authorities or the US Securities and Exchange Commission, and in the "Risk Factors" section of its Form 20F for the year ended May 31, 2012.
Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.
Medicure Inc.
Dawson Reimer
President & COO
[email protected]
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Thursday, August 08, 2013
Hallmark Channel Fall 2013 Preview; 9th Annual PaleyFestPreviews: Fall TV in Beverly Hills and New York City
We can't release the Hallmark Channel Fall 2013 schedule just yet, since it starts in October, but we do have a preview of what is to come. As we previously announced, Home Improvement is joining the Hallmark Channel schedule. The award-winning and much loved comedy, Home Improvement, starring Tim Allen, joins the line-up of TV's classic comedy series on the Hallmark Channel, with a 10-hour Labor Day marathon on Monday, September 2, starting at 10am ET/PT. Follow the trials and tribulations of Tim "The Tool Man" Taylor, the host of the do-it-yourself TV show, "Tool Time," as he balances life with his wife Jill, played by Patricia Richardson, and their three mischievous boys: Brad (Zachery Ty Bryan), Randy (Jonathan Taylor Thomas) and Mark (Taran Noah Smith). Although he is an excellent salesman and TV personality, Tim Taylor is spectacularly accident prone – particularly due to his personal mantra of "More Power!" - often causing massive disasters on and off the set to the dismay of co-workers and family, leading him to regularly seek advice from his loyal co-host Al (Richard Karn) and his know-it-all neighbor Wilson (Earl Hindman). The sitcom will join the regular Hallmark line-up in October and we will announce the timeslots at a late date. Elsewhere, The Daytime Emmy® nominated Home & Family, the most unique, original program on cable television, returns to Hallmark Channel on Monday, September 30 @ 10am/9C for its second season with all new shows. The nationally syndicated series The Better Show is coming to The Hallmark Channel on Monday, September 30 as well and will air weekdays at 1PM. In primetime, catch the drama-filled season finale of Debbie Macomber's Cedar Cove on Saturday, October 12 at 8pm ET/PT, as the series will continue to air every Saturday until then. The potential new primetime series Dead Letters will premiere Saturday, October 5 at 9pm ET/PT starring Eric Mabius. Then the following week will have a new series premiere following the Cedar Grove finale, Hallmark Channel's Newest Original Primetime Series When Calls the Heart will have a 2-hour special extended pilot Saturday, October 12 at 9pm ET/PT. The series will star Lori Loughlin, Maggie Grace, Stephen Amell, and Jean Smart. And finally, movie premieres include: Dear Dumb Diary on Friday, Sept. 6 at 8; Garage Sale Mystery starring Lori Loughlin on Saturday, Sept. 14 at 8; The Watsons Go To Birmingham starring Anika Noni Rose, David Alan Grier on Friday, Sept. 20 at 8; and The Hunters starring Victor Garber, Michelle Forbes, Alexa Vega on Friday, Oct. 25 at 8. Stay with us soon for the full Hallmark Channel Fall 2013 schedule, which will begin in October with the addition of Home Improvement to the line-up. Since we didn't technically give you a Fall 2013 schedule today, we will be back tomorrow with the MeTV Fall 2013 schedule, which we couldn't release today. Come on back! The Paley Center for Media will present the 9th annual PaleyFestPreviews: Fall TV on September 6–13, 2013 at The Paley Center for Media in Beverly Hills, and on September 7-8 at The Paley Center for Media in New York. Citi has been named official card of the week-long festival and TV Guide Magazine returns for the sixth year as the festival's media partner. PaleyFestPreviews: Fall TV, will feature screenings of the most highly anticipated news shows of the fall season, including: CBS: We Are Men, Mom, The Millers, The Crazy Ones, and Hostages; The CW: The Tomorrow People, Reign, The Originals; Fox: Brooklyn Nine-Nine, Sleepy Hollow, Dads, Almost Human, Enlisted; ABC: The Goldbergs, Back in the Game, Trophy Wife, Super Fun Night, Lucky 7; NBC: Ironside, Sean Saves the World, Welcome to the Family, The Michael J. Fox Show, and The Blacklist. The Beverly Hills location will include interactive panel conversations featuring the stars and producers of new series including We Are Men, The Tomorrow People, Brooklyn Nine-Nine, Back in the Game, Trophy Wife and Ironside. Panel conversations will be streamed live globally during each program at paleycenter.org/live. Viewers are invited to follow the conversation and submit questions on Twitter @paleycenter using the hash tag #PaleyFest. Additionally, in Beverly Hills the festival will feature two special programs, a "Fall Farewell" salute to the SHOWTIME® drama Dexter®, on Thursday, September 12, featuring members of the cast & creative team for a screening and conversation; and a "Fall Flashback," Reflections: China Beach 25 Years Later, featuring a reunion of the cast & creative team, on Friday, September 13. Sponsorship for the "Fall Farewell" event is provided by Samsung Smart TV. All programs in Beverly Hills will begin at 7:00 pm PT and are open to the public, with the exception of the Fox program which will begin at 5:30 pm. Tickets to the 2013 PaleyFestPreviews: Fall TV events, as well as to the "Fall Farewell": Dexter® and "Fall Flashback: China Beach 25th Anniversary Reunion" will go on sale to Paley Center Members on Saturday, August 10 at 9:00 am PT, and will go on sale to the general public on Monday, August 12 at 9:00 am PT. For ticket prices and further information on each of the programs please visit the Paley Center website: www.paleyfest.org. Tickets to the 2013 PaleyFestPreviews: Fall TV events in New York are free and open to members and to the general public, but tickets must be reserved in advance. Paley Center Members may RSVP right now, and the general public may RSVP beginning on Friday, August 9 at 12:00 pm ET. For further information on each of the programs please visit the Paley Center website: www.paleyfest.org. You can view the full schedule for both the Beverly Hills and New York screenings on their website as well.
New on DVD/Blu-ray (July/August)
07/08 - The Monkees - The Complete Series (Blu-ray)
07/12 - Grady - The Best of Grady
07/20 - Bob's Burgers - The Complete 5th Season
07/26 - Family Matters - The Complete Seventh Season (WBShop.com)
07/26 - Where's Huddles? - The Complete Series (WBShop.com)
08/02 - Hangin' with Mr. Cooper - The Complete First Season (WBShop.com)
08/09 - Maude - The Complete Final (Sixth) Season
08/23 - Brooklyn Nine-Nine - Season Three
08/23 - Superstore - Season One
08/23 - The Wonder Years - Complete Series (New Slipcase Version)
More TV DVD Releases / DVD Reviews Archive / SitcomsOnline Digest
Sitcoms Airing Tonight
Wednesday, August 24
The Goldbergs - "The Dirty Dancing Dance" (ABC, 8:00PM ET/PT) (Repeat)
Beverly helps Erica plan a "Dirty Dancing" themed dance at school, only to turn on Erica when she realizes it may be inappropriate. Meanwhile, Murray tries to learn dancing with Adam with little luck.
The Goldbergs - "12 Tapes for a Penny" (ABC, 8:30PM ET/PT) (Repeat)
Adam learns about a mail-order music club and sets up a scheme to get as many tapes as possible, but Beverly believes Erica is behind it all. Meanwhile, Barry works on getting the approval of Bill, Lainey's father, but he refuses to budge.
The Goldbergs - "Big Orange" (ABC, 9:00PM ET/PT) (Repeat)
Barry's favorite shirt is hated by Beverly and girlfriend Lainey, so they hatch a plan together to destroy it. Once his shirt goes missing, Barry asks Adam and Erica to investigate. Meanwhile, Murray decides to tear down the family tree house, leaving Adam distraught.
The Goldbergs - "Dungeons and Dragons, Anyone?" (ABC, 9:30PM ET/PT) (Repeat)
Adam convinces Coach Mellor to let him be team captain in gym class. He betrays his friends by picking the jocks first, causing the two rivaling squads to battle it out with the game the nerds know best – Dungeons and Dragons! Meanwhile, Erica decides where she wants to go to college but encounters resistance from both Beverly and Murray.
Modern Family - "Express Yourself" (ABC, 10:00PM ET/PT) (Repeat)
Phil has the crazy idea of going on a spontaneous trip to Paris with Claire; the only problem is that they are both so ridiculously tired but try to push through it. Meanwhile, Jay has taken over their bathroom remodel, which proves to be pretty hazardous for Gloria, Manny and Joe. Cameron's sister Pam is staying at the house after her husband has left her, but her emotional outbursts are driving Mitchell crazy, and he's afraid it's setting a bad example for Lily. And Haley and Andy go on a wild night bender.
black-ish - "Hope" (ABC, 10:30PM ET/PT) (Repeat)
When the kids ask some tough questions in the midst of a highly publicized court case involving alleged police brutality and an African-American teenager, Dre and Bow are conflicted on how best to field them. Dre, along with Pops and Ruby, feel the kids need to know what kind of world they're living in, while Bow would like to give them a more hopeful view about life. When the verdict is announced, the family handles the news in different ways while watching the community react.
Bunk'd - "Dance in My Pants" (Disney Channel, 8:00PM ET/PT)
Tiffany and Zuri are hoping they'll dance with a cute boy at the annual dance; Emma finds out that Lou and Xander have a history.
Sitcom Stars on Talk Shows (Week of August 22)
Wednesday, August 24
- John Krasinski (The Office) - Watch John on The Late Late Show with James Corden at 12:37am on CBS.
- Adam Pally (The Mindy Project/Happy Endings) - Adam appears on The Late Late Show with James Corden at 12:37am on CBS.
- Jason Biggs (Mad Love/Drexell's Class) - Jason is a guest on @midnight on Comedy Central at midnight.
- Cobie Smulders (How I Met Your Mother) - Cobie stops by Conan at 11pm on TBS.
- Marc Maron (Maron) - Maron appears on Chelsea on Netflix.
- Tori Spelling (Mystery Girls) - Tori is a guest on a repeat of The Talk on CBS at 2pm ET/1pm CT-PT.
- Terry Crews (Brooklyn Nine-Nine/Are We There Yet?/Everybody Hates Chris) - Terry guest co-hosts a repeat of The Talk on CBS at 2pm ET/1pm CT-PT.
- Tika Sumpter (The Game) - Tika is a guest on Popcorn with Peter Travers on ABC News.
- Emeril Lagasse (Emeril) - Emeril appears on a repeat of Rachael Ray, so check your local lisitngs.
- Hilary Duff (Younger/Lizzie McGuire) - Hilary teams with Michael Symon to make a Chicken Parmesan Hero on ABC's The Chew at 1pm ET/12pm PT/CT.
- Tia Mowry (Instant Mom/The Game/Sister, Sister) - Tia will be on New York Live on WNBC in New York at 12:30pm ET.
- Casey Wilson (Happy Endings/Marry Me) - Casey talks about One Mississippi on NBC's Today in the 10am hour.
- Sabrina Carpenter (Girl Meets World) - Sabrina dishes on the fate of Girl Meets World Season 4 and the big wedding scene on People Now at 8:30am.
- John Krasinski (The Office), Charlie Day (It's Always Sunny in Philadelphia) and Margo Martindale (The Millers) - The cast of The Hollars will be on People Now at 8:30am.
- Joey Bragg (Liv and Maddie) - Joey is a guest on Good Day New York on WNYW-Fox5 in New York sometime between 7-10am.

subset: commoncrawl


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Bees raise their body temperature to cook an invading hornet. Bees are badass mofos.
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Bad dog. Bad dog. Aw no, don't feel bad.
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Crikey the kookaburra Laughs with the Audience in a Zoo.
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Baby seals frolicking under a waterfall in New Zealand.
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His name should definitely be Ferdinand. He's clearly been hanging out with sheep.
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Is there a way to evolve back into these, please?
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Intelligent mice doing amazing tricks.
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Dog plays with squeaker toy and sing.
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Dog goes back to grass, tumble into faceplant.
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To be fair, the bar for dancing flamingos has been set super low.
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Considering that monkeys are not good pets, this is a surprisingly peaceful duo.
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âPIECE BY PIECEâ - After a decade of working together to overcome everything that stood against them, fractures begin to form between the scientists of the Manhattan Projects. The thrilling FEEL GOOD, BAD SCIENCE series continues in THE MANHATTAN PROJECTS #13: PIECE BY PIECE!
EXCLUSIVE: Deadpool Dons the Venom Symbiote in "Back In Black" #1 First Look
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Beta Culture: New Intro — Part 1
Beta Culture: New Intro — Part 2
Part 1 / Part 2 / Part 3 / Part 4 Full Culture Already described above, full cultures cover everything, every aspect of life, providing both game and gameboard for living. Full cultures have an elaborate social framework that takes into account every aspect of life, with all the details worked out.In New York state where I live, full cultures include the Amish and Hasidic Judaism. However confining or silly they might look to those of us outside them, from the inside they provide a place … [Read more...]
Beta Culture: New Intro — Part 3
Part 1 / Part 2 / Part 3 / Part 4 Values Every culture has a set of core values – its basic concepts of who and what "we" are. What we hold dear, what we're proud of in contrast to all other, lesser cultures. The easy part is finding things to include. The hard part is making it work, deciding on the various traditions and values and making them stick.So what would Beta Culture include?Of course the foundation of Beta Culture – its most basic value – is atheism. Rationality. A reason-b … [Read more...]
Beta Culture: New Intro — Part 4
Part 1 / Part 2 / Part 3 / Part 4 Making It Happen Here's the rub: How do you create an entire culture?But I suspect it would actually take very little effort. At the least prompting, people take on actions and beliefs that become cultural traditions, perpetuating them indefinitely. Some years back the song 'Tie A Yellow Ribbon Round the Old Oak Tree' made a splash on the radio, and though the concept of ribbons to greet long-lost family is older than the song, it triggered a sudden leap on … [Read more...]
Randall Eades: Culture and Chaos
This guest post by Randall Eades follows an online conversation about Beta Culture. ---------------Okay, I've read enough of your Beta Culture to get an idea of where you're going with it. It's interesting. But before I get into that, I'd like to back up a bit to where we began — the end of the world as we know it— to fill in a little history of my point of view.Twenty-five years ago I read a piece by some science fiction writer in which he described some predictions for the future he … [Read more...]
Beta Culture: Culture Itself
In pursuit of my Beta Culture concept, I've been thinking a lot about Culture over the past couple of years, and I've recently been making some interesting connections. I like to think I'm getting close to understanding the meat of it. Here's a recent thought:Your culture offers you Values, Ways, and Place.VALUES are obvious: Honesty is the best policy. People are suckers and deserve what they get. Hard work is the stuff of life. Honor your mother and father. Family above all. Never stop … [Read more...]


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Working on strengthening your relationships with clients and prospects will greatly impact your business development client base. The best perspective to bring with you is viewing your clients as an integral aspect of your activities. The combination of excellent service and a positive relationship sets the stage for future business. Relationships imply the trust factor is there which will make them think of you in the future. If you are truly passionate for learning guitar, then you should find out best GuitarJamz review for your proper guidance.
Leave no stone unturned in your search for new clients because you'll find possibilities in the most unexpected places such as with the colleges you attended. All you have to do is be signed up or join alumni organizations, and then have everyone in your business do the same. What you'll definitely find are prospects, and then you will have a way and reason to make contact with them. But also don't forget to network with other alumni because this is how you create more relationships, and also include social media in this effort.
Never forget that you will have some kind of effect on people you deal with. You will field questions sometimes and not know the answer, and rather than trying to snow them, simply tell them you don't know. The fear with this is you may think they'll view that in a negative way. Naturally you are the expert and think you should never not have a good answer. The best course of action is being sincere about it, and then let them know you will get them the answer. Your clients will not overlook the fact that you were honest.
A great source of leverage with business development is actually social media today. Going well beyond what Facebook and Twitter will do for you, LinkedIn is your best bet for getting professional contacts. Most people get confused with Facebook post-IPO, which makes the latter two not as popular to use. The people you want to connect with for direct development needs probably are not active at Twitter. Finding user groups on LinkedIn is easy, regardless of what industry or expertise you may have. So what you need to do a showcase your expertise and business on a LinkedIn profile to attract the right clientele. There are so many parts of business development that are beyond the realm for the business owner. How well you will do really depends not on marketing methods but rather the details of any business who becomes a client. You're in a tough business that not many can do, but the potential gains for you and your clients are immense.
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The chassis for this car was purchased in 1929 but the body, built separately as was often the case with ultra-luxury cars of its day, wasn't completed until 1931. The hugely wealthy original owner, George Whittel Jr., was heir to a vast family fortune and had been prescient enough to pull out of the stock market just before the crash of 1929.
This car has only ever had five owners -- up to now -- and had been driven only 12,500 miles.
General Motors unveiled a large convertible concept car that shows one possible future for Cadillac.
|AP's Kathleen Carroll defends Clinton investigation
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Written by Jen Finn
Commercial fishing requires a lot more than sea legs and a sturdy boat. I knew this, but I re-learned it first-hand this past week.
I've just returned from several days in the extraordinarily scenic Alaskan fishing town of Cordova, where I got a broad and in-depth perspective of where one of my favorite seafood items – Copper River salmon – comes from and how it's managed by the fisherman and the State of Alaska.
A healthy fishing community DOES take a village.
"People are really letting us take care of their fish," said Mike Poole, part of Cordova's fleet since 1978 and a former member of the Copper River/Prince William Sound Marketing Association's board. "It's the public's natural resource, and we are privileged to fish it."
Interestingly, the chain-restaurant demand for fish and seafood has been growing. A survey in 2011 by the Alaska Seafood Marketing Institute found "a steady increase in consumption at chain restaurants" with 36 percent of consumer respondents saying they ate more than two years before, and 58 percent saying they ate the same amount.
Read the full story at Nation's Restaurant News>>
The Atlantic States Marine Fisheries Commission recently released the preliminary agenda and public comment process for its 75th annual meeting which will be held October 23-27 in Bar Harbor, Maine.
Read more ...
The Obama Administration recently announced that it is looking for candidates to be considered for a sustainable fishing prize.
The White House Champion for Change for Sustainable Seafood designation will honor individuals for "contributing to the ongoing recovery of America's fishing industry and our fishing communities."Read more ...


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Availability Check
Availability check is one of the key functionalities in sales document processing.
The confirmation of delivery of goods to customer while entering a sales
document is carried out on the basis of this check.
Availability check can be carried out on the deadline of goods availability that
would be necessary to consider the picking, packing and shipping time.
Availability check can only be carried out if transfer of requirements take place
for goods from sales to purchase or production.
System provides for three types of Availability check
explained as under:
ATP basis check
Available To Promise (ATP) is calculated from warehouse stock,
planned inward movement of stock (purchase orders, planned orders etc.) &
planned outward movement of stock (sales orders, deliveries, reservations
Check against Product Allocation
Product allocation is used for period based distribution of products
for specified customers or regions. This check is over the normal availability
check. It is carried out in cases where production is low and goods produced
need to be distributed to customers and ensured that first customer is not
allocated complete quantity.
© 2011 SAP AG. All rights reserved. 4
Check against Planning
Check against planning is performed against planned independent
requirements which are generated from a demand planning program.
Replenishment Lead Time (RLT) is time that is needed to
order or produce requested material. RLT is calculated
based on time maintained in master data.
ATP check Including RLT
Availability check is calculated only up to end of RLT. If the material availability
date calculated on basis of current date lies after RLT, system confirms the
item in spite of insufficient stock in the assumption that stock would be
procured or produced by that time. Thus confirmation can be sent to customer
in this case.
Replenishment Lead Time
© 2011 SAP AG. All rights reserved. 5
20 pcs of stock requested by customer can be confirmed if RLT is included
with ATP check because although 20 pcs of stock may not be available on day
requested the date falls after the lead time specified for item and hence stock
would theoretically be available.
© 2011 SAP AG. All rights reserved. 6
ATP check Excluding RLT
If RLT is not included in ATP check system performs a check on the
unrestricted stock and scope of check on inward and outward movement of
Similar example as above excluding RLT check, system would confirm
the item only when stock would actually be available.
© 2011 SAP AG. All rights reserved. 7
Control Parameters of Availability Check in Sales
Following SD specific control parameters need to be maintained.
Checking Group
Checking group forms one of factors for specifying scope of
availability check. It is used for grouping of materials for individual or
collective requirements. It is assigned in material master Sales/Plant view.
Checking Rule
Checking rule forms the other factor in specifying scope and is
assigned to each transaction in sales and distribution. The checking rules are
predefined in system.
Schedule Line Category
Schedule line category had additional check to turn on/off availability
Control Parameters
© 2011 SAP AG. All rights reserved. 8
Following elements can be included in scope of availability
Safety Stock
Stock in Transfer
Blocked Stock
Quality Inspection
Inward/Outward movement of goods
Purchase requisitions & orders
Planned & Production orders
Sales & Delivery requirements
Dependent requirement
© 2011 SAP AG. All rights reserved. 9
Requirements generated in Sales & Distribution need to be
transferred to material requirements planning to ensure the
quantities ordered are available to be delivered on time to
Customer. This is called transfer of requirements (TOR).
TOR are of two types:
TOR with individual requirements
A line for each individual requirement is created in availability
overview for each sales document and schedule line. This helps in tracking the
initiating document. System uses this for special stock scenarios like Make-to-
order stock, project stock etc. It can also be used for standard orders if sales
order volume is not large and requirements need to be tracked at item level
Transfer Of Requirements
© 2011 SAP AG. All rights reserved. 10
TOR with collective requirements.
Collective requirements combine various requirements based on
following criteria:
Storage Location
Transaction &
Requirement class
These requirements can either be created daily or weekly. The
documents initiating collective requirements cannot be directly identified but
can be traced via list of orders for material
© 2011 SAP AG. All rights reserved. 11
Control Elements of significance in TOR are
Requirement type
Requirement class
Checking group
Schedule Line category
TOR needs to be switched on at Requirements class and
Schedule line category level for proper processing.
Plant must be defined at item level in sales document.
Checking group must be defined in material master in
Sales/plant view.
© 2011 SAP AG. All rights reserved. 12
You use backorder processing to track customer sales orders received for which
the stock has not yet been shipped. Normally, this occurs when the available
quantity of the item is insufficient to fill the order. The backorder process
enables you to check the item quantities that are missing. Once received in stock,
you can ship these shortages to your customers
There are two types of Back order processing
1. Manual Backorder
2. Reschedule Backorder
Manual Backorder Processing
In this process we can reduce the confirmed quantity of line item of one sales
order and reallocate that quantity to item of another sales order.
© 2011 SAP AG. All rights reserved. 13
Rescheduling Process.
When it should use:-
- When we reduce the confirmed quantity of one sales order and want to allot to
another sales order automatically on basis of delivery priority rule.
-Or for one few sales orders created during non availability of stock that time
system will provide delivery date to in future date on basis of delivery scheduling
calculation after that stock is available before Delivery confirmation date then
we wants to re-determine the available date and delivery date on basis of
delivery priority rule.
The Delivery priority is taken from the customer master in sales order and can
be used as a sort criterion for orders during rescheduling process.
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Request additional information and/or documentation from Mortgage Loan Processors and Mortgage Loan Originators through appropriate timely feedback....


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Confederations Cup: Spain
Defending World Cup champion Spain looks to maintain its place atop the soccer world at the Confederations Cup.
Video: Star power on display in Brazil | Fans of the Confed Cup
Defending World Cup champion Spain looks to maintain its place atop the soccer world at the Confederations Cup.
Video: Star power on display in Brazil | Fans of the Confed Cup
You've seen the replay by now, especially since we learned Dallas Cowboys quarterback Tony Romo has a fractured vertebrae in his back and will likely miss a significant portion of the season. Romo was sliding down when he was hit by Seattle Seahawks defensive end Cliff Avril from behind, and then Romo writhed around in pain. Cowboys fans noticed and they have let Avril know they didn't like the hit.
(c) 2016 Time Inc. Patrick Reed Wins Barclays, Secures Ryder Cup Spot Patrick Reed was a shot behind Rickie Fowler after 54 holes but rallied to win The Barclays to open the FedEx Cup playoffs.Two things about the Ryder Cup: One, Your team, whichever
With a little over a month to go in the regular season, the Texas Rangers have put themselves in exceptional shape to compete for a World Series title. At 77-54, the club holds an 8.5 game lead in the American League West, and midseason additions of Jonathan Lucroy and Carlos Beltran have strengthened an already solid lineup. The benefit of bringing in a 19-year veteran like Beltran is that he can find a way to inspire his teammates even when he's not in the lineup.
Let's complete our analytics-based positional analysis this fantasy football draft season by focusing on tight ends and market share in order to hopefully find some sleepers and avoid some busts. A key is that the offensive system in place is not different this year, which hurts, for example, the market-share projection for Delanie Walker given that new OC Terry Robiskie is coming from an offense that threw 15.9 percent of passes to Atlanta tight ends last year.
Kyle Larson got his first points win on Sunday (Getty). Kyle Larson sprinted away from Chase Elliott on the race's final restart to grab the first Sprint Cup Series win of his career at Michigan on Sunday. Elliott was the leader on that restart, which came with nine to go.
Bobby Wood celebrates Hamburg's opening goal against Ingolstadt. It'll still be worthwhile checking on Fabian Johnson at Borussia Moenchengladbach, center back John Brooks at Hertha Berlin, the rebirth of Julian Green at Bayern Munich and injury comebacks of strikers Aron Johannsson at Werder Bremen and Terrence Boyd at newly promoted Leipzig.
Sports Illustrated's best photos from the first leg of the 2016 FedEx Cup playoffs at Bethpage Black in Farmingdale, NY.
Most of our readers likely aren't well-versed in the world that is Argentine club soccer. Because of the dominance of the European game, it's not the most popular league in the world, but it doesn't lack quality and is always exciting to watch. Soccer fans may know of clubs like Boca Juniors, River Plate. Maybe even Independiente, San Lorenzo or Racing, but the name Giovani Lo Celso or Rosario Central probably doesn't ring a bell for most. Well, he's a name you'll be hearing more of moving forward. The dynamic Argentine midfielder, playing for for Rosario Central on loan from Paris Saint-Germain, showed off some crazy skills on Saturday that his French club would likely describe as "magnifique."
Paige VanZant made her return to the Octagon at UFC on FOX 21 after her impressive runner-up performance on Dancing With the Stars. Did her brief time under the mainstream spotlight make the 22-year-old soft, or did it help her footwork? Paige looked good early, she was moving well and had sharp leg kicks, but Paige would be overpowered by Bec Rawlings in the clinch, after which Paige would back out and do strange spinning kicks that wouldn't come withing multiple feet of Rawlings.
Victor Cruz suffered a torn patellar tendon in November 2014 and since has battled calf and groin injuries with constant setbacks, false starts and, worse yet, false hope. "It felt great just to be with my teammates and put this 80 jersey back on and to get the love of the crowd and the people again and go out there and be in position to make a few plays as well," Cruz said via NJ.com. New York Giants wide receiver Victor Cruz played in his first NFL game in almost two years (AP).
When another New York Yankees game begins, another Gary Sanchez home run is likely right around the corner. The sensational rookie slugger continued his barrage on Saturday afternoon, connecting for his 11th home run in the Yankees 13-5 win against the Orioles. Gary Sanchez is the fastest player in @MLB history to 11 home runs (23 games).
For two decades, Kobe Bryant saw everyone and everything as an obstacle to overcome: The Pacers, Sixers, Nets, Magic, Celtics, Tim Duncan, Gregg Popovich, Smush Parker, a torn Achilles. It didn't matter. Kobe's work ethic and drive had him rising above it all. His focus hasn't changed now. Kobe was on the Jim Rome show, and the topic of the new-look Warriors with Kevin Durant came up, along with the "woe is me" attitude of some players (and plenty of owners and GMs). "I would have thought less about myself if I looked at that move and said, 'That's unfair,'" he said. "If you're a real competitor, you look at that and say, 'OK, lace 'em up. Let's go. I don't care how many players you have over
If it were anyone other than Vin Scully being honored, this unique tribute by the Los Angeles Dodgers might give us nightmares. Every member of the Dodgers current roster, coaching staff and front office appears to be included in the photos. By our count, which admittedly could be off a Vin or two, there are 105 extra Vins and one real Vin.
Romain Grosjean was left frustrated after an issue with his energy recovery system (ERS) during Sunday's Belgian Grand Prix cost him a possible points finish. Haas Formula 1 driver Grosjean started 11th at Spa, but made a superb start to run as high as fifth in the early stages. However, the decision to pit just three laps before the race was red flagged combined with the ERS issue that cost him straight line speed dropped Grosjean outside of the points. The Frenchman enjoyed a strong final stint, but was unable to finish any higher than 13th for the American team. "Well, it was a very good start and a very good first lap. Unfortunately, I didn't have any top speed in the beginning of the race,"
Nebraska transfer Andrew White has committed to Syracuse, he announced Sunday.
The Tennessee football team will honor one of the university's legends during the 2016 season. Vols coach Butch Jones confirmed Saturday that his team will have a commemorative sticker on their helmets to honor the late Pat Summitt. Summitt, the longtime Tennessee women's basketball coach, died on June 28 from Alzheimer's disease.
Arizona Coyotes GM John Chayka is deftly playing the system when it comes to the salary cap to the point that some might accuse him of exploiting loopholes. If the NHL bristles as such tactics, they're at least not showing it in public. In taking on the absolutely dead money of Chris Pronger and Pavel Datsyuk along with the possibly dead money of Dave Bolland, the Coyotes are getting to the cap floor while saving money in the actual cash they're dishing out. The Score's Ian MacLaren succinctly explains the savings they're enjoying thanks to these clever trades: That's how the league is viewing Arizona taking on the salaries of Chris Pronger, Pavel Datsyuk and Dave Bolland. The cap hits amount
Keith Schlosser, SNY.TV Twitter | Archive Though the New York Knicks look to be much improved on paper following a solid offseason, it's worth recognizing that chemistry takes time to develop. With so many new and/or moving pieces coming together, the team will need to put the work in to get to know one another, both on and off the court, to be successful. Carmelo Anthony, Willy Hernangomez and Mindaugas Kuzminskas are all fresh off the Olympics. They all deserve time to recuperate before even thinking about early team meetings and workouts. But a good chunk of the rest of the squad has gotten a head start on building some of that necessary familiarity and camaraderie with one another. Obviously
One of the most impressive things about the Minnesota Vikings' new stadium was how it looked on television. It looked, for the most part, like the Vikings and San Diego Chargers were playing outdoors. That's not easy to pull off in an enclosed stadium
New York Yankees rookie Gary Sanchez is officially making history while helping lead a team resurgence that few outside the Yankees organization saw coming. In Friday's 14-4 win against the Orioles, Sanchez went 3-for-5 with four RBIs and three runs scored. Overall, Sanchez now has 10 homers in 22 games, which is a power feat only accomplished by two other players.
Watch as Dale Earnhardt Jr. makes a controversial move to earn the win back in 2006 at Michigan International Speedway and Carl Edwards voice his displeasure.
As a Jordan Brand athlete, Russell Westbrook is under the same Nike umbrella as former teammate Kevin Durant. But his latest Jordan spot, released Friday, has a very pointed tagline: "Some run, some make runways." Given the circumstances, it's hard to interpret that as anything other than a reference to Durant signing with the Warriors and Westbrook signing an extension with the Thunder.
CSN Philly's Jim Salisbury reports that a team claimed Phillies starter Jeremy Hellickson on trade waivers, but the two clubs were unable to work out a deal. As a result, the Phillies pulled Hellickson back from trade waivers, which means he's ineligible to be traded for the rest of the season. Hellickson, 29, has had a nice bounce-back season after three poor years from 2013-15. He's 10-8 with a 3.80 ERA and a 131/36 K/BB ratio in 154 innings. The Phillies could attempt to re-sign Hellickson in the offseason. It's also possible the club makes a qualifying offer — estimated to be worth $16.7 million — so that the Phillies will at least get back a compensatory draft pick if Hellickson opts to
A wild Saturday saw Chelsea cruise at home, United battle for three points against Hull and Tottenham and Liverpool finish level at White Hart Lane.
Virginia unveiled new football uniforms Saturday to kick off the first season under Bronco Mendenhall. The Cavaliers will wear a blue jersey with white pants at home and an all-white combination on the road. Additionally, UVA has an alternate orange jersey available for home games to go with its usual white pants.


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'Wow... this reading is amazing, you are amazing. I'm blown away, its so spot on.
Everything about the reading is exactly my cats and what they are dealing with. I'm smiling as I write this as you described them both so well.'
Alana, July 14th, 2016
© Edwina Gustafson 2016


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Mercury invests $20 million in US facilities
by Jonathan Revitt on 12 Nov 2012
Mercury celebrates ground breaking at facility Mercury Marine
To help maintain its position as the world's leading marine engine manufacturer, Mercury Marine is investing $US20 million ($A19.2 million) to further develop facilities at its headquarters in Fond du Lac, Wisconsin, USA.
Two major construction projects are at the heart of the development, which will deliver significant improvements across a range of important areas.
'It's all about growth and commitment to technology and product development,' said Mark Schwabero, President of Mercury Marine.
The investment will see an enhanced capacity in Mercury's product development, engineering, component manufacturing and fabrication.
Product testing is another area to benefit, with Mercury Diesel products being accommodated along with sterndrive and inboard engines.
'All of which will help keep Mercury at the forefront of boating – delivering better products which out-perform and out-last the competition – and that will make our dealers stronger across the ANZP region,' said John Temple, Mercury's General Manager for the Australia, New Zealand and Pacific region.
At the ground breaking ceremony, Mr Schwabero used the same shovel which broke the ground when the Fond du Lac plant was originally built almost 50 years ago.
It's expected the new facilities will be fully operational by the end of 2013.
If you want to link to this article then please use this URL: www.powerboat-world.com/103721
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This year the 16th annual Asia Superyacht Rendezvous will kick off with a sensational opening party aboard the beautiful phinisi-style sailing yacht Dunia Baru.
Posted on 9 Aug
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Independent and incremental prognostic value of left ventricular ejection fraction determined by stress gated rubidium 82 PET imaging in patients with known or suspected coronary artery disease
- Received:
- Revised:
- Cite this article as:
- Lertsburapa, K., Ahlberg, A.W., Bateman, T.M. et al. J Nucl Cardiol (2008) 15: 745. doi:10.1007/BF03007355
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Background. Whether left ventricular ejection fraction (EF) obtained by gated rubidium 82 positron emission tomography (PET) myocardial imaging can identify patients at risk for future cardiac events is unclear.
Methods and Results. Consecutive patients with known or suspected coronary artery disease who underwent dipyridamole stress gated Rb-82 PET imaging were evaluated. Scoring of perfusion was accomplished by use of a 17-segment model. EF was automatically generated. Patients were stratified based on summed stress scores (SSSs) (0–3, 4–8, or >8) and stress EF (>50%, 40%–49%, or <40%). All-cause mortality was determined by use of the Social Security Death Index. Of 1,441 patients, 132 (9.2%) died during mean follow-up of 2.7±0.8 years. Annualized mortality rates across SSS groups were 2.4% for SSS of 0 to 3, 4.1% for SSS of 4 to 8, and 6.9% for SSS greater than 8 (P<.001). Similarly, annualized mortality rates were 2.4%, 6.2%, and 9.2% for the group with EF greater than 50%, group with EF of 40% to 49%, and group with EF lower than 40%, respectively (P<.001). On multivariate analysis, the addition of EF to clinical and perfusion variables significantly increased the globalX2 (73.3 to 107.7,P<.001). Integration of EF with SSS significantly enhanced risk stratification.
Conclusion. EF assessed by stress gated Rb-82 PET imaging provides independent and incremental prognostic information and, hence, should be routinely incorporated in risk assessment.


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Well, Azumanga was a 4 panel manga and was a great anime. But, …
- Tags: Chuunibyou, Little Busters, Moe, Otaku, Rankings, Tari Tari, VIP Quality
Comment on Top 50 Anime of 2012 by Anonymous:
Well, Azumanga was a 4 panel manga and was a great anime.
But, yeah. Kill Me Baby was crap.
Anonymous made other comments on this post:
- Top 50 Anime of 2012:
Oniai beat Acchi Kocchi? Faith in Japanese taste in anime: lost.
- Top 50 Anime of 2012:
kill me baby? pfft. sword art onlin? pfft
- Top 50 Anime of 2012:
acchi kocchi deserver more
- Top 50 Anime of 2012:
I'm glad Sword Art Onlin made the list and Sword Art Online did not.
- Top 50 Anime of 2012:
so much trash, and no ok things like another, sankarea, fate/zero, tasogare otome x amnesia, jormungad, arcana familia, magi?
Recent comments by Anonymous:
- Top 10 Worst Manga-to-Anime Adaptations:
Yeah, the anime for DB added a shit load of plotholes and a lot of the fights were way too drawn out, especially in the Buu saga and the Red Ribbon saga.
- Pokemon Go Road Kill "Japan's 2nd!":
He's still to blame for not being 100% at attention behind the wheel. The cyclist is to blame somewhat, but the driver is still at fault because he was driving while not paying attention.
- Berserk Musou "Dark-Skinned Casca?":
https://i.redd.it/g6u2nyobzn6x.png The new anime fucked it up, I don't know if they fixed it or not, I can't deal with the shit CGI.
- Yamato Futanari Ero-MMD Dancing Lewdly:
Will anyone ever get cum animated right in 3D hentai?
- Pokemon Go Road Kill "Japan's 2nd!":
I can see the headlines… WOMAN KILLED BY a reckless driver charging his phone because he played too much POKEMON GO


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Senator Paul McKinley says he feels it's important to find out what the Knoxville community thinks before the Iowa Senate approves a resolution in regards to the local VA campus.
Keywords: Iowa Senate, Knoxville VA, Paul McKinley, VNRC
49'ers quarterback Colin Kaepernick chose not to stand when "The Star-Spangled Banner" played before a game because he wanted to bring attention to the problems black Americans face. Was that OK?
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call: (641) 842-3161 | (641) 628-8672


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Seibertron.com - The Ultimate Transformers Fansite
Mousesi2k wrote:Very very nice collection mate! Just got a quick question for ya.
In this picture, can you tell me Animated Series Optimus Prime this is? Im trying to find the best looking OP for my animated collection and this one looks really nice.
MemoryOverdrive wrote:Wow! Nice collection they look great must have a whole room dedicated to them.
............Burn wrote:Alpha Bravo...He's a helicopter in a team of jets. That's just dumb.
Return to Share Your Transformers Collection
Registered users: Bing [Bot], Bronzewolf, D-Maximus_Primal, Google [Bot], Google Adsense [Bot], KennethAkfaer, Moonshot, MSNbot Media, paul053, PrymeStriker, Sabrblade, SiameseDream, Sigma Magnus, SJ21, SureShot18, Tyrannacon, william-james88, xMXUx, Yahoo [Bot]


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Coming soon: Training. Have 30 seconds to spare? Help us choose our first course!
Working with cool illustrator to create grunge style website. www.alpo.fi
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The incidence of twinning and higher order multiples has increased dramatically over the last two decades.1 The greatest contributor to this explosion in multiple gestations has been delayed fertility and the use of assisted reproductive technology.1
It is well known that multiple gestation is related to increased risk of perinatal morbidity and mortality and consequently long term health sequelae.1 The impact of multiple gestation on women's health is less known. A few previous studies of the issue suffer from various methodological limitations, including small sample size, inadequate control group and inappropriate outcome measures.2,3
Pregnancy is associated with a number of physiologic changes for adaptation and accommodation of the fetus.2–4 There is a 50% increase in plasma volume and a corresponding increment in cardiac output. This allows for increased blood volume for uterine perfusion for delivery of nutrient and oxygen exchange. There are changes in coagulation factors with an increase in procoagulants and a decrease in anticoagulants.5 This hypercoaguable state has a protective effect to the mother during delivery by decreasing haemorrhage. These physiologic changes, although having inherent advantages for mother and fetus, can lead to adverse maternal outcomes such as venous thromboembolism.
Multiple gestation, having increased placental and fetal mass, is likely to have increased physiologic responses compared with singleton pregnancies.2–4 For instance, stroke volume and heart rate are both increased in multiple gestation suggesting that there is a decrease cardiac reserve. These exaggerated physiologic changes in multiple pregnancies are potentially associated with an increase in adverse maternal outcomes such as pulmonary oedema, venous thromboembolic disease and even death. The objective of this article is to determine whether there is an increase in adverse maternal outcomes in multiple gestation pregnancies.


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Top Trending Hotels Near Vail Ski Resort
Get 200 Nectar points when you book your hotel
Simply enter your Nectar card number when prompted. Your points will be credited 30 days after you return from your trip.
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The Arrabelle at Vail Square, A RockResort
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Iron Maiden's Plane Transports Tourists
Iron Maiden's customized Boeing 757, which is emblazoned with their logo and the flight number 666, is owned by Astraeus airlines, where front man Bruce Dickinson is also registered as a pilot.
The jet is used by the airline as a commercial plane when the group isn't on tour - but staff normally remove the Iron Maiden sign.
But Thomson Airways bosses had to call the vehicle in at the last minute to transport tourists from Edinburgh Airport to destinations in Greece and Turkey after another jet was grounded.
A representative for Astraeus airlines tells The Scotsman, "Normally our planes are always plain white so they can operate for any airline. Iron Maiden have just finished the overseas leg of their world tour and the plane has gone straight into use, as a plane being used by Thomson Airways had some mechanical difficulties and has been taken away for repairs. That's why we haven't had a chance to take the logo off."
A Thomson Airways rep adds, "It has been quite interesting for them, definitely. It's a little different to what you normally see on the Tarmac. We will be using it for the next few days on short-haul flights to destinations such as Paphos in Greece, and Dalaman in Turkey."
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- Early Concept Art of 'Captain America: Civil War' Sees Ant-Man Fighting the Cap


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Is maternal PTSD associated with greater exposure of very young children to violent media?†
- †
This research was supported by the following grants awarded to the first author: NIH grant K23-MH068405, Bender-Fishbein Fund Award, Sackler Institute for Developmental Psychobiology at Columbia University Award. We dedicate this article to the memory of our dear colleague Mark Davies who helped to inspire the research discussed.
This study examined media viewing by mothers with violence-related posttraumatic stress disorder (PTSD) and related media exposure of their preschool-age children. Mothers (N = 67) recruited from community pediatric clinics participated in a protocol involving a media-preference survey. Severity of maternal PTSD and dissociation were significantly associated with child exposure to violent media. Family poverty and maternal viewing behavior were also associated. Maternal viewing behavior mediated the effects specifically of maternal PTSD severity on child exposure. Clinicians should assess maternal and child media viewing practices in families with histories of violent trauma exposure and related psychopathology.


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The Conrad Jupiters Magic Millions Selected Yearling sale continued on a strong note Saturday, with a record track at the sale session which followed the Magic Millions race day at Gold Coast racetrack in Australia.Yearlings sired by the champion ill- fated sire Danehill shared the honor of being the sale topper tonight when each brought final bids of $350,000 (about US$270,550)Magic Millions managing director David Chester said he was "absolutely thrilled" with the night session."Like our first two sessions on Thursday and Friday, tonight saw more strong selling and most importantly a strong clearance rate," Chester reported. "Buyers jumped at their chance to secure a quality yearling tonight and our clearance rate climbed even higher which was just fantastic."Late in the session the sale's most active buyer to date Graeme Rogerson snapped up a three quarter brother to stakes winning sire Springsteen (ex Lake Alexandrina), earlier on the Japonila colt sold to Gregory Pearsall for the same amount.Other appealing yearlings to buyers tonight included youngsters by Snippets, Stravinsky, Redoute's Choice and Fasliyev.Buyers during tonight's session included locals Gerald Ryan, Gillian Heinrich, Kelly Schweida and John Wallace, while others included Gai Waterhouse, Graeme Rogerson, Rick Hore-Lacy, Bill Mitchell, Lee Freedman and Bart Cummings.
Live Now: OBS August Yearling Sale
Magic Millions Sale Topped by Danehill Yearlings
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"I love this series"
I read the books and loved them so I bought the audio books and listened to them and it was like a new story all over again. The narrators were amazing!
"When can we get the next book in the series."
Very well read and a great story.
Different topic - interesting
She is clear, and makes you feel you are in the story yourself.
Dark Fever
"Cover Misleading, Story Still Great"
I have never seen the print version, so I cant compare
At the end of the book where Mac comes into her own when she begins to fight the hourdes of monsters. That is pretty cool.
Not so much as a favorite scene, but I enjoy the insight of Mac and her southern background. She is very down to Earth. She is stubborn and a bit reliant on her girlie things like pink nailpolish and matching sandals, but she has great morals and she cares. She goes into a speech about how you can only live life two ways, with hope or with fear. I thought that speech was so moving, I paused the recording and wrote it down to share with my husband. It was very uplifting.
Georgia Peach Meets the things that go bump in the night.
So, the front cover of the book is a hot, steamy naked couple. Im expecting the usual in this book, a boy girl romance. The girl loves the guy and cant tell him, the guy loves the girl but wont even admit it to himself until its almost too late, a lot of longing then hot sex weaved into a paranormal circumstance. Nope, this is all paranormal circumstance and zero hot sex. Unusual but its true. There is no relationship at all between boy and girl really, but dont let that scare you away. The story is really good and kept me coming back for more. wink. Also, the narration I have to comment on. I am from Georgia just like our heroine, so lets just say Im an authority on a Georgian accent. When I listen to the story, its like Blanch from the Golden girls is reading it. If your clueless as to what that means, well lets just say its a little exagerated. Dont get me wrong, the story was read with correct expression, like I said, its just a bit over exagerated. The Irish accents of the characters are awesome but the tones are little off. The man in the story, Jericho, is supposed to be some really dark handsome, young guy. He sounds like an elderly leprachaun. I have to keep telling myself he is young and good looking even though he sounds like an 89 year old, stumped over nursing home resident! Despite these misgivings. I plan to listen to the entire series. The story really is good.
"Can't get enough of this series"
I would listen to this book again just so I wouldn't miss anything. I have read the whole series and loved it, am now listening to the audios.
I liked the story line and how the main characters interact.
Joyce Bean does an excellent job of narrating. I have listened to other books she narrated and I think she is great. I search for books narrated by her.
I could have listened to this book in one sitting, unfortunately time did not allow.
I am looking forward to the rest of the series on audio.
"Good Story Line"
This book has a great story line.
The unsuspecting twists and turns.
The reader makes Barens sounds like a gravely old guy when he's really in his 30s. That's a bit hard to listen to, but otherwise, I really enjoyed it.
I am a Youth Services Librarian at a public library and I love my job. I am also a runner and I love listening to great books while staying healthy. That's Elsie in the picture...she is my favorite running partner and typically perks her ears up during the tense portions of the books :)
"Different than I thought it would be."
For the most part, I did like the reader. The story was a little different than I thought it was going to be and there was just too much world building in this first one and not really enough story. I was really frustrated with Mac's inability to accept the Fae world that she is now a part of.
I will eventually finish the series, because I think I will like the others better.
Mac was a good character with her Southern drawl.
"Great start"
Great start to the series. Kept me on the edge of my seat often. Great suspense. Joyce Bean does a great job with the different character voices. Wish she was around for books 4 & 5
"to hard on the ears"
the voice was like nails on a chalk board.the leading lady was the one person who will send you screaming the other way.
it took 5 trys to get through this book and i only maid it because i was out of credits.
Dont do it. I tried twice to listen to this book. Thought the first time I wasnt in the mood for this type of book so i gave it another chance. Mistake, it was just as terrible the second chance i gave it. Save your money/credits.
Gina Marie
"Best series ever!"
Great series of books that have everything,romance,mystery,fanstasy.I Love this series of books,as you listen they just keep getting better & better! Have not found anything better.
these audiobooks are very unique,highly recommend them!
The narrators flaws do not distract from the great story line


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Keyword bidding is the most powerful lever you can pull to increase or decrease volume quickly. That's why it's also the most overused lever in paid search campaigns. Campaigns that rely too heavily on tactical bid changes to drive efficiency and volume never reach their complete potential.
It's impossible to discuss bidding without discussing program goals. If you manage a ROI-focused campaign, then your approach to bidding will be vastly different than if you manage an impression-based branding campaign.
Because our experience lies heavily in new customer acquisition and ROI-focused search programs, the theme of this article will assume ROI as the primary success metric.
(Just joining us? Catch up with Part 1 and Part 2.)
Define Business Rules
In a retail environment, the keywords in your program are a reflection of the products you sell. Profit margin defines the level of tolerance retailers will have as it relates to what they are willing to spend to drive a sale.
For example, if a retailer is selling in both the ink cartridge category and the office furniture category, and the ink cartridge category drives a 35 percent greater profit margin than office furniture, that retailer may allow a lower ROI in ink cartridges to maximize volume and bottom-line profit.
Some of the most successful paid search campaigns align these business rules with their paid search programs. Understanding this level of detail allows for clear bidding strategies at a category and product level.
Hyper-bidding: An Infinite Loop
If you've dabbled in computer programming, then you're familiar with the concept of an infinite loop. It's a process that can't stop executing because its conditional expression can never be true. It's like a dog chasing its tail.
Hyper-bidding, or the act of making multiple bid changes per day in reaction to your competition or in an attempt to reach a specific goal, is equally as futile and unproductive.
The SERP and competitive space is too dynamic for hyper-bidding to be effective, with the exception of extremely high-volume keywords that allow for statistically significant decisions to be made quickly. These high-volume keywords are usually the exception and not the rule.
It's important to give keywords, or portfolios of keywords, time to accumulate enough data to allow you to make an informed decision on which way the bid pendulum should swing. Several bid adjustments per week, not day, is usually most productive.
Bid Testing
Google recently rolled out a new beta feature in AdWords named Experiments. You can find it under the Settings tab within a specific campaign.
This easy-to-use tool allows you to split-serve an "experiment" or test bid versus your current control bid. If you've ever wondered how a portfolio of keywords would perform at a $0.50 CPC versus a $0.70 CPC, this tool will make it easy for you to test out your hypothesis in a clean testing environment.
Know Your Peak Hours and Days
In working with one retailer, we achieved optimal ROI between the hours of 3 p.m. and 4 p.m., and that a wider efficiency net was cast between the hours of 11 a.m. and 5 p.m. We took this data and coupled it with bidding strategies to increase CPCs during the hours of the day that we knew would allow for greater spend tolerance.
If your ROI goal is X, and you're achieving 3X at certain times of day, elevate your bids to capture more demand during these times — as long as it holds within your efficiency threshold.
Conversely, we found the largest variance of clicks to orders were occurring between the hours of 8 p.m. and 11 p.m. Decreasing bids and suppressing volume in these scenarios allowed us to move those dollars to support the more efficient days of the week and times of day.
Once you've identified your peak days and times, setting the complementary bid rules is a cinch.
Under the same Google AdWords Settings tab that you found Experiment, you'll also find Ad Scheduling. Within the Bid adjustments feature of Ad Scheduling you can easily throttle your bids based on times of day and day of week.
Vanity Kills
A final word of caution as we close out the bidding discussion. You don't have to be in position 1, or even in premium positions 1 through 3 to be "winning" in paid search. This is even truer on highly focused ROI campaigns.
Rely on the data to dictate your optimal position and CPC. More times than not we find our keywords performing optimally at CPCs that hold ads on the right rail in average positions of 4 through 6. It can be a comfortable place to be, especially if you're the type who likes to be sitting in profits.
Stay tuned for the fourth and final article of this series where we'll cover the critical topic of paid search measurement.
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Even when Google removed the right-side ads in February, it didn't dare touch the highly popular right-side Shopping ad (previously PLAs) unit for shopping results.
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17 useful search marketing stats from Merkle's Q2 2016 report
This morning, Merkle released their quarterly Direct Marketing Report, ahead of Google's own Q2 earnings announcement and it makes for a bumper stat-filled read.


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I would recommend Cabo Transfers to anyone without hesitation.N. A. Blackshear, Philadelphia, PA
Cabo transfers made traveling with children easier and our vacation better.Grant, San Diego
If anyone wants a transfer while in Cabo you guys are the ones to use.Jeff and Shirley Fox, Bend Oregon
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DNV GL successfully completed its due diligence work of the offshore wind farm "Nordergründe" in the North Sea, reviewing and quantifying the technical risks of the project.
Offshore oil and gas operators in the Gulf of Mexico are evacuating platforms and rigs in the path of Tropical Depression No. 9.
The Bureau of Safety and Environmental
The new Barge Master Gangway will be presented at the joint booth of Barge Master and Bosch Rexroth during the international offshore trade exhibition ONS (Offshore Northern Seas) in Stavanger.
Siegfried Schmerer already dreamed of becoming a captain as a young boy. Later, as a sailor on a coaster, he suffered from seasickness. Though he thought about giving up,
Buyout firm Advent International Corp has hired Morgan Stanley & Co and Grupo BTG Pactual SA to advise on the sale of a controlling stake in TCP Terminal de Contêineres de Paranaguá SA,
Samskip has completed the acquisition of Euro Container Lines AS, building on a strategy for growth in the Nordic area to make its largest ever acquisitive move in Norway.