text:
New Emphasis in Cancer Drug Tests: The Elderly
By GINA KOLATA
Published: February 15, 2000
Every winter in the frigid town of South Bend, Ind., Dr. Rafat Ansari notices a definite increase in the number of his breast cancer patients who choose to have mastectomies rather than lumpectomies. The reason, he says, is quite simple.
While the two treatments are equally effective in early breast cancer, there are considerations that go beyond the medical, Dr. Ansari said. With a mastectomy, in which a woman's entire cancerous breast is removed, once the surgery is completed the treatment is done.
But women who have lumpectomies, in which just the cancerous tumor is taken out, must have six weeks of radiation treatments. For many of Dr. Ansari's patients, elderly women, living alone and afraid to go out on the icy roads, the thought of the daily trek to a radiation center is simply too much. They choose to have the breast removed instead.
''These little old ladies will tell you, 'Six weeks of radiation treatments? I'm not driving,' '' said Dr. Ansari, a cancer specialist in private practice in South Bend.
It is a complication hardly dreamed of in the 1980's, when cancer researchers triumphantly announced that many women with small tumors did not need to have mastectomies. But then again, the large national study that established this, like nearly every other cancer study until now, had virtually no patients over 65.
Now, in what they say is an unprecedented initiative, cancer researchers are designing studies specifically for older people. The new approach, these researchers say, is forcing them to ask a different sort of question. Instead of seeking the most aggressive treatments, intended to keep cancer at bay for decades, they are looking for the mildest treatments for people whose life expectancy may be no more than 10 years. That means asking whether radiation after lumpectomy extends life for older women with breast cancer, whether chemotherapy is helpful for elderly patients with colon cancer, lung cancer or breast cancer, and whether a mild chemotherapy treatment is helpful for elderly lung-cancer patients.
Cancer researchers say there is a great need for studies focusing on the elderly. The typical cancer patient is not a parent with school-age children, but a grandmother or grandfather living alone or in a nursing home. For example, while a woman of 35 has a 1 in 2,500 risk of developing breast cancer in the next year, a 75-year-old woman's risk is closer to 1 in 300, noted Dr. Hyman Muss, a professor of medicine at the University of Vermont.
''With the aging of our population, the average cancer patient is going to be 70 years old,'' said Dr. Bruce Chabner, the clinical director of the cancer center at the Massachusetts General Hospital in Boston. ''But the average patient in clinical trials is 45 or 50.''
Younger patients often want, and can tolerate, extremely aggressive treatments. With decades of life before them, they have every incentive to go to any length to try to wipe their cancers out. That was why many sought bone marrow transplants, a regimen that used doses of poisonous chemotherapy drugs so high that only the youngest and healthiest patients could survive them. It was not a suitable treatment for an 80-year-old woman with heart disease or kidney disease or emphysema. Nor was it in demand among the elderly.
''Often people in this age group do not want aggressive treatment,'' said Dr. Jeffrey Abrams, who coordinates breast cancer trials at the National Cancer Institute.
One of the first attempts to address the needs of elderly cancer patients was a study, sponsored by the cancer institute, that was designed to help patients like Dr. Ansari's: if a patient is 70 or older when breast cancer is discovered, can she get away with just a lumpectomy and hormonal therapy with the antiestrogen drug tamoxifen? Are those six weeks of radiation really necessary?
Another study, in which Dr. Chabner is participating, involves lung cancer patients who are 70 and older, testing a mild chemotherapy regimen with the drug taxol. ''It's relatively easy to take and nontoxic,'' Dr. Chabner said.
But the breast cancer trial showed the way, cancer experts said. Dr. Abrams said that an impetus for the trial was the cancer institute's own data. Elderly women just were not having lumpectomies.
Some researchers thought doctors were encouraging mastectomies because they did not think old women cared about their breasts. But Dr. Abrams said that often the women themselves were refusing lumpectomies because of the problem of getting to a radiation therapy center or other medical problems that made radiation therapy difficult for them.
Esther Rahfeldt, an 84-year-old widow who lives alone in La Porte, Ind., said she refused to consider radiation therapy when she discovered a lump in her breast last December. It was not just the inconvenience of radiation treatments, she said. She also worried about her pacemaker. She did not want to have it removed and reset after the radiation therapy. Her doctor told her that her only option then was a mastectomy. ''I told him that if it came to that and it would be my life, then to take the breast,'' she said.


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Bernie Ecclestone in Formula 1 bribe probe
- 20 July 2011
- From the section Business
Formula 1 supremo Bernie Ecclestone has been named by prosecutors in Germany as allegedly bribing a former banker during the sale of the sport in 2006.
Gerhard Gribkowsky, in charge of the sale of BayernLB's stake in F1, stands accused of taking a $44m (£27m) bribe.
In return, prosecutors allege, Mr Ecclestone received $41.4m in commissions from the bank, as well as a large payment to a family trust.
Mr Ecclestone said he expects to be cleared of any wrongdoing.
A court will now decide whether Mr Gribkowsky will stand trial on the charges.
The allegations revolve around the sale of BayernLB's stake in Formula 1 to private equity group CVC Capital Partners, which still owns the commercial rights to the sport.
CVC said it had no knowledge of any alleged payments to Mr Gribkowsky.
The firm bought majority control of F1 from Bernie Ecclestone's family trusts and a group of investment banks.
Mr Ecclestone remains F1's chief executive and retains a large shareholding in the sport.


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There are plenty of different types of people. There are also some international students every somester from different parts of the world to add diversity to it
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It a small campus and I do not socialize with other people besides athletes.
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If you hang out with people you can relate to, you'll enjoy your experience. And always have a diverse group, don't be clique-ey!
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Just as diverse as the culture here on campus is, so is the dress. We have girls who rock things that I can't, or wouldn't want too.. but it's them. Most people don't look at you weird hardly ever. The typical student's look for girls is jeans, pretty shirts or graphic tees and tennis. At UIW it's very laid back, we're here for school not to impress anyone. But you'll meet people on all sides of the spectrum and many inbetween.
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There are different groups, there are gamers, music nerds, anime people, drama geeks, kind of like high school but more accepting of intermerging friends.
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UIW has more women than men, but that does not stop the student population from looking for potential significant others. Sure, UIW is a Catholic university, but that does not stop students from hooking up, whether it is on campus in a dorm room or off campus at a party. You will also see more serious relationships as well. The serious relationships heard about more than the hookups.
The typical dress code on campus is casual. You will often see guys wearing basketball shorts and girls wearing Victoria's Secret sweats, and of course, you will also see girls sometimes looking very glamorous. UIW students are not trashy or nerdy looking. They look relaxed and casual, not too over the top, but sometimes you will spot someone in their pajamas, which is understandable because sometimes college life can get quite busy and hectic.
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terrific tour guide and bus driver....
the trip was exactly as advertised and met our expectations. I would highly recommend this trip if you have 1 day to journey outside the city.
A wonderful experience with such great local knowledge. Our tour guide was excellent! The moment from departure to return was effortless and run with professional efficiency and service. Girona is unforgettable, Figueres fascinating and the Dali Museum mind blowing. Highly recommended for the tour guide alone, let alone the stunning scenery, intriguing history and cultural experience.
This tour was amazing!
Tour was well organized, tour guide was knowledgeable. Girona,Figueres and Dali museum are well kept with full of teaching points.
Highly recommend this tour! Girona is incredibly beautiful, the Dali museum is as cool as I hoped it would be, our tour guide was awesome, knowledgeable and very, very patient with a huge group of people, many of which asked the same questions over and over. God bless him! I'm looking into another tour because this experience was so great. Good job
Great tour
This tour was amazing!
Great trip and would highly recommend. Guide did well.
Great guides. Fun! Definitely worth the $.
Great if you're looking to get out of Barcelona for the day. The guides are very knowledgeable.
Girona is beautiful and if you're a Game Of Thrones nut, you'll enjoy the novelty of knowing the town was used to film some King's Landing scenes for season 6.
Dali theatre is a unique experience however if you're wanting to see an extensive Dali collection, you won't find it here. The theatre holds more of Dali's personal art collection rather than his work.
Make sure you make time to head next door to Dali Joies and view the amazing jewellery Dali designed.
Excellent day tour and well run.
VIRGI A United States of ...
Wonderful tour!! Our tour guide was very well informed and pleasant, taking the time to answer all our questions and sharing her knowledge of the various sights. Viator gave excellent instructions on where to meet, length of trip/tour and approximate return time, so it was easy planning. The Dali Museum were so very interesting, well worth the visit and Figueres was charming. The City of Girona was very beautiful with a rich history and lovely people. This tour was great and we highly recommend it.
Fantastic trip. Girona being Game of Thrones filmimg location was an enexpected surprise and our giude was able to show us exact filming spots. Dali Museum is a must for art lovers.
Love love love this tour. Best museum that I have ever been to. Only negative is that it is a huge bus with 40pax. Next time, I will look for a small group tour.
Convenient to visit two cities in one day. I got plenty of time to visit the Dali Museum.
excellent tour
We enjoyed a relaxing bus ride to Girona and Figueres. The tour was informative,comprehensive and enjoyable. Both Girona and Figueres were well worth visiting and we were glad we did.
The only way to visit these sites for our vacation itinerary. Very well planned and guided experience.
Girona is a beautiful old city, the day we spend there they were celebrating the flower festival, it was an amazing experience.
Excellent...Our tour guide, Dina on the bus was wonderful as well as our tour guide, Ann in Gerona. She was a little difficult to hear on the busy streets in Gerona without a microphone, however. Gerona was so beautiful and Figueres and the Dali Museum extremely good. I loved every minute!
We thought the guide who traveled with us was just excellent - so professional, completely bilingual, and very knowledgeable. Outstanding.
We thought the guide who traveled with us was just excellent - so professional, completely bilingual, and very knowledgeable. Outstanding.
Love to Travel United States of ...
Highly recommended. Too many things to see and too little time. It's a whole day trip and we were very tired at the end. You'll have two different guides. They are all very knowledgeable and accommodating. The bus doesn't have bathroom but you can ask the driver to stop at a pit stop.
It was our tour guide's first day--she was really wonderful.
Very knowledgeable tour guides, great tour!
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One police van - MH-02-A- 4084, four cops, one night, one job, one hell of a ride, is what Hriday Shetty's new directorial film titled 'Chaalis Chauraasi', in one line. Produced by MAASK Entertainment Pvt. Ltd. in association with Filament Glo (India) Pvt. Ltd, Chaalis Chauraasi stars extremely talented and experienced actors like Naseeruddin Shah, KK Menon, Atul Kulkarni and Ravi Kishan. The film is written by Yash-Vinay and the music in the film is by Lalit Pandit.
Language: Hindi
Status: Released
Rajesh Sharma, Zakir Hussain, Naseeruddin Shah, Atul Kulkarni, Kay Kay Menon, Ravi Kissen
Editor: Bunty Nagi
♦ View complete cast & credits
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$ 89.99 SALE: $ 62.99 Not Eligible For Return
You'll gain fashion points in the Extra Credit by Chinese Laundry. This cute and fierce flat features a tan leather upper with leopard print fur at the pointed toe. Edgy spikes trim the back for a bold expression.
G by Guess
Gennie - Gold LL
G by Guess
Gennie - Black SY


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100 percent CNC machined aluminum, single pin sight features A.R.M.O.R sight pin technology, and yardage dial for rapid adjustment to the yard from 20-80 yards. Yardage scales are marked in one yard increments, and only require sighting in at 20 and 60 yards to select one of the included 52 color coded tapes. Comes with a 1 5/8" sight housing with 3 ft. of wrapped fiber optic. Tool-free micro adjust windage. Green sight ring for quick target acquisition . Includes DS tapes and Mathews Harmonic Dampers. Accepts lens kit B and HHA blue burst light.
Portable full-body elk decoy that folds up to fit in your pack. Sets up quickly with poles or string and clip hanging system. Head on cow elk visual pulls bulls in close. Includes Fred Eichler DVD with tips for decoying elk. Dimensions: 47"x30" (unfolded), 19"x12" (folded).
Mid-weight gloves constructed of a polyester interlock outer fabric, accent orange spandex panel for flexibility and a micro-fleece inner fabric. Features an inner wrist opening that allows for wearing over a release, touch tech finger tips for touch screen devices, silicone printed palm for a secure grip, carbon alloy technology for odor adsorption, DWR treated to help repel light moisture and a wicking treatment for moisture management.
Features S3 and MicroWick technology. 4 Direction Stretch ensures superior comfort. Made with merino wool. System Layer One.
The largest cutting diameter broadhead in the Slick Trick line. Offers exceptional holes and performance. Blade Thickness: .035", Cutting Diameter: 1 1/4".
Features S3 and MicroWick technology. 4 Direction Stretch ensures superior comfort. Made with merino wool. Pullover style with ¼ zip front. Has a vertical zippered chest pocket. System Layer One.


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A mid-weight wool blend structures a modern, casual blazer with soft construction.
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- Approx. length from shoulder: 28 1/2".
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DOD officials are not following all the steps they're supposed to before signing the check for a sole-source contract, GAO finds. (Stock image)
The Government Accountability Office found that defense acquisition officials often fail to justify sole-source awards to small, disadvantaged companies even though a new law requires written justification when the contracts are worth more than $20 million.
The Defense Department made eight such awards between March 2011, when the new rule took effect, and March 2012. DOD officials did not meet the new justification requirement on six of those contracts. The Air Force awarded the two contracts that complied with the requirement.
GAO said the other contracting officials were unaware of the requirement or were confused about the type of justification needed. On two Army contracts, for example, officials prepared justifications but based them on the Competition in Contracting Act of 1984.
Under the new rule, officials must address five specific elements, including showing why the sole-source contract is in the agency's best interest and ensuring that it is paying a fair price.
The law does not specify at which stage an agency needs to justify its decision, but it should happen before contract negotiations begin.
In December 2012, GAO recommended that the Office of Federal Procurement Policy issue guidance clarifying the justification rule.
DOD officials had no comments to add to GAO's report.
About the Author
Matthew Weigelt is a freelance journalist who writes about acquisition and procurement.
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In the latest issue: grid security, agile development, BYOD and more!
Get the full issue
The latest version of the Defense Department-wide Enterprise Service Management Framework places more emphasis on managing IT risk.
Despite GSA's efforts to accelerate the FedRAMP approval process, the lack of agency reciprocity puts the program's central goals at risk.
Got some early-career colleagues who are doing great things in federal IT? Nominate them for FCW's 2016 Rising Star awards.
The agency software inventories required under the draft category management policy will be treasure maps that lead to efficient, effective, streamlined buying and unprecedented savings.
As experts warned of the "dire" threats posed by outdated federal technology, lawmakers grilled top feds, debated workforce issues and inched closer to backing a $3.1 billion fix-it fund.
The agency is making strides in developing and deploying border technologies but still has some weaknesses.
Agencies have spent almost $23 billion on legacy IT over the past three years, according to reports to Congress. Is a revolving fund the answer?
The United Kingdom will go live with its governmentwide digital identity platform, GOV.UK Verify, in the coming days. The U.S. government will need a little more time.
What contracting officer representatives really think is needed to fix contract management.
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JFK Website (0)
Digital Archives (2)
Common Search Term: Sharp
Papers of John F. Kennedy. Pre-Presidential Papers. Presidential Campaign Files, 1960(1)
Papers of John F. Kennedy. Presidential Papers. White House Staff Files of Harris Wofford(1)
Political campaign, 1960(1)
African Americans(1)
Sharp, Nolan, 1920-2002(1)
This folder contains suggestions for campaign songs including: "If Anybody Can Kennedy Can," by Vince Rago; "Kennedy for President," by James A. Waters; and "The Kennedy Song," lyrics by Evelyn Gianfala and music by Sharp and Arnold.
Search powered by Oracle Endeca ®.
JOHN F. KENNEDY PRESIDENTIAL LIBRARY AND MUSEUMColumbia Point, Boston MA 02125 (617) 514-1600


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Hours: 6:00pm- ~9:30pm;
Listing short-URL: http://meetu.ps/rw7n ;
Official event URL says
just across the street from the campus after Saturday sessions. As always it's free food and drinks (2) for the first 150 attendees to Code Camp so please check in early and get a ticket at registration. It's a great way to relax and chill with friends and presenters after a marathon of sessions.
"Text LFSM1F: This is a sub-event of [masked](Sat)-30(Sun) SoCalCode Camp (at CSF): OCAndroid's visit --you need to read that discussion thread for details applying to this & every sub-event, including for (how to RSVP to this particular sub-event: point LFSKXT)."
(LTBKIT=Welcome!, Android Developers, Users, & Entrepreneurs
of the US.California.SoCal.Orange County area!
Since 2009, we are Your oldest & largest professional community group
and we are Here to Serve You!
where OCAndroid&more do admin&tech discussion&articles 2011-now,so JOIN!
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I have built two firewood sheds for seasoning and storage of fuel wood using pallets and sheeting I found in free wood piles at a nearby industrial park. The used corrugated roofing is from a barn that was being dismantled and moved. I caulked the old nail holes to make the roofing waterproof.
I positioned the woodsheds with their backsides facing the prevailing winds to keep the rain and snow from blowing in, while also providing maximum airflow to dry the wood.
Mark Jacobson
Spokane, Washington
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I have an ASP.NET MVC 3 .NET application under Visual web developer Express 2010.
By default it is build as 'Any CPU'. When tested, Environment.Is64BitProcess always returns false (I have Windows 7 64 bit). I tried Stack Overflow question Change target CPU settings in Visual Studio 2010 Express for both x86 and x64, but it always results in an error, something along the lines of:
Cannot load type 'MyApp.UI.MvcApplication'.
and points to the
global.asax file with only one line:
<%@ Application Codebehind="Global.asax.cs" Inherits="MyApp.UI.MvcApplication" Language="C#" %>
How could I fix it?


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Blogs Liberty and Power Cliopatria Awards (Nominations Open): Best Blog in HistoryOct 31, 2005 11:13 am
Cliopatria Awards (Nominations Open): Best Blog in History
Make your nominations here. The rules allow bloggers who are not academic historians to be nominated. Let's hope that Liberty and Power makes a good showing.
The nominations for Liberty and Power's award contest for best classical liberal academic blog are now closed and the official contest will begin in a few days. More later.
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Once a week, Stack delivers a mix of the most interesting new music on the web, handpicked by the Hype Machine team. Here's a recent mix.
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Check them out!
All information on this page is available in RSS and JSON formats for non-commercial, attributed use (CC) by developers.


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Fit Life Articles
Learning how to do two classic foundational exercises—the push-up and the hip hinge—can help you build get fit, strong and flexible for life. Begin by mastering these two oldies but goodies, watch your strength, fitness and flexibility skyrocket while you avoid injuries.
Maintaining a healthy weight can be challenging and, for some people, even more difficult than losing weight. The good news is that achieving lasting weight maintenance is possible. Use these 13 tips to help you succeed at maintaining your weight-loss goals.
Most snacking calories come from high salt, high fat and high calorie processed foods. These snack foods are cheap and convenient, yet they don't offer much in the way of nutrition. It's time to spring clean your kitchen and your diet by tossing these three food products...


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Definition from Wiktionary, the free dictionary
Scottish Gaelic[edit]
From Middle Irish fúasclaid ("releases, delivers; redeems; relieves, assuages; solves"), a late form of fúaslaici, fúasailci ("looses, opens, sets free; releases, delivers; redeems; loosens; dissolves, annuls") formed by metathesis, probably from Old Irish do·fuasailci ("loosens, relaxes; sets free, releases; dissolves, resolves (into constituent elements); unsheathes; solves (a question, etc.); relaxes, remits (bondage, an obligation, etc.); dissolves, destroys"), through loss of the first preverb.
fuasgail (past dh'fhuasgail, future fuasgailidh, verbal noun fuasgladh, past participle fuasgailte)


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Single or married, life can be challenging and we want to come alongside you with biblical truth as you navigate life's challenges. While studying the Word of God, we often need help living it.
Men of the Word and Women of the Word are 9-week mentorship programs for students aspiring to serve the church.
The Ministry Leaders Internship trains men and women for their unique leadership roles in ministry. Ministry Leadership Interns will work under the office of Student Life to promote a culture of discipleship.
At Southern Seminary, we recognize the vital role that women play in God's Kingdom. To that end, we've created a variety of special programs and ministries to address women's needs and equip them for whatever calling God has placed on their lives.
Grow in community, communication, and spirituality with other students at Southern.Learn More
New Student Orientation will lay the foundation for your time at Southern Seminary and give you a smooth transition into the Southern Family. Orientation is required for all new Louisville-area M.A. and M.Div. students.Learn More
The seminary community gathers to worship in Alumni Memorial Chapel on Tuesday and Thursday at 10 a.m. All offices will be closed during this time.See the Preaching Schedule


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When it comes to the care of your clients, you have high expectations. And we have high expectations of ourselves.
From our office staff to direct caregivers, we do everything we can to live our mission for our clients and to fulfill our promises to them:
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From the Blog
Are Men's Brains Smaller Than Women's?Jul 26, 2016 Read Full Entry »
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I'm trying to set up a simple blog for the remainder of my semester so I can write about music and movies. I know I don't have to create any type of special design, but I want it to look at least somewhat impressive.
The problem I'm currently having is an issue with my NAV element. I can define the width and background color, but the bar remains black outside of the defined areas. I'd like to have a transparent.
The other issue I'm having is with the border-radius declaration in IE9. It renders appropriately in Firefox, but not IE9 for whatever reason. Any help with these two issues would be greatly appreciated. Many thanks beforehand.
URL: www.musingsofaweirdguy.blogspot.com


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Tech Tip
If you often have multiple putty, terminal, ssh or screen sessions connected to various remote servers, one good way to organize them is to have a small script that places the name of the remote server in the title bar:
#!/usr/bin/perl -w $name = $ARGV[0]; unless ($name) { $name = `/bin/hostname` } print "\033]0;$name\007";
Save this, and make it executable. If, for example, you save it as name, you simply can run name to place the name of the current server in the title bar of your current session.
If you want to label the session with something besides the hostname of the server, just specify the label on the command line:
# name "Mail Server"
Tech Tip
Most Linux distros come packed with documentation in the /usr/share/doc directory, but rarely is there an easy way to get an overview of what's there. The following script creates a master index of all the index.html files in /usr/share/doc and outputs it as index.html in the user's home directory:
#!/bin/bash input_dir=/usr/share/doc output_file=~/index.html cat >$output_file <<EOF <html> <head> <title>$input_dir</title> </head> <body> EOF find $input_dir -iname 'index.html' | \ sed 's/[^ ]*/\<br\>\<a href="file:&"\>&\<\/a\>/' \ >> $output_file cat >>$output_file <<EOF </body> </html> EOF
Tech Tip
The script command is used to log an entire session. Type the command script at the command prompt, and script then copies everything you type and its response to the file typescript. Script starts a sub-shell; when you want to stop saving the session, end the sub-shell (normally with Ctrl-D or by typing exit).
A very useful feature of the script command is that it can output timing information to a separate file. The script and the timing information then can be used to replay the script.
The following example creates a script and timing data (timing data is always written to standard error):
$ script -t 2> timinginfo Script started, file is typescript $ ls Desktop test scripts redbooks $ pwd /home/jagadish $ hostname homepc $ exit exit Script done, file is typescript
The entire terminal session then can be replayed later (with exact timing) using the scriptreplay command:
$ scriptreplay timinginfo $ ls Desktop test scripts redbooks $ pwd /home/jagadish $ hostname homepc $ exit exit
Script is a useful tool for training and educational purposes.
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One of the best things about the UNIX environment (aside from being stable and efficient) is the vast array of software tools available to help you do your job. Traditionally, a UNIX tool does only one thing, but does that one thing very well. For example, grep is very easy to use and can search vast amounts of data quickly. The find tool can find a particular file or files based on all kinds of criteria. It's pretty easy to string these tools together to build even more powerful tools, such as a tool that finds all of the .log files in the /home directory and searches each one for a particular entry. This erector-set mentality allows UNIX system administrators to seem to always have the right tool for the job.
Cron traditionally has been considered another such a tool for job scheduling, but is it enough? This webinar considers that very question. The first part builds on a previous Geek Guide, Beyond Cron, and briefly describes how to know when it might be time to consider upgrading your job scheduling infrastructure. The second part presents an actual planning and implementation framework.
Join Linux Journal's Mike Diehl and Pat Cameron of Help Systems.
Free to Linux Journal readers.View Now!
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- Stunnel Security for Oracle
- The Firebird Project's Firebird Relational Database
- Murat Yener and Onur Dundar's Expert Android Studio (Wrox)
- SUSE LLC's SUSE Manager
- Managing Linux Using Puppet
- My +1 Sword of Productivity
- Non-Linux FOSS: Caffeine!
- Google's SwiftShader Released
- SuperTuxKart 0.9.2 Released
- Doing for User Space What We Did for Kernel Space
Geek Guides
With all the industry talk about the benefits of Linux on Power and all the performance advantages offered by its open architecture, you may be considering a move in that direction. If you are thinking about analytics, big data and cloud computing, you would be right to evaluate Power. The idea of using commodity x86 hardware and replacing it every three years is an outdated cost model. It doesn't consider the total cost of ownership, and it doesn't consider the advantage of real processing power, high-availability and multithreading like a demon.
This ebook takes a look at some of the practical applications of the Linux on Power platform and ways you might bring all the performance power of this open architecture to bear for your organization. There are no smoke and mirrors here—just hard, cold, empirical evidence provided by independent sources. I also consider some innovative ways Linux on Power will be used in the future.Get the Guide


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- Manufacturer reference: 6558B001K
- Date first available at Amazon.ca: June 18 2012
- Average Customer Review: 1 customer review
- Amazon Bestsellers Rank: #388,283 in Electronics (See Top 100 in Electronics)
Canon EOS T4i DSLR Camera with 3 Canon Lens Pro Pack: Includes - Canon EF-S 18-55mm f3.5-5.6 IS - Canon EF-S 55-250mm f/4-5.6 IS Autofocus Lens - Canon EF 50mm f1.8 II Autofocus Lens, 3 Piece Pro Filter Kit and much more... 6558B001
We don't know when or if this item will be back in stock.
- STM Lens Support for Quiet AF in Movies
- 18.0MP APS-C CMOS Sensor
- DIGIC 5 Image Processor
- 3.0" Vari-Angle Touch Screen LCD
- ISO 100-12800, Expandable to 25600
Product Details
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Product Description
The Canon EOS Rebel T4i Digital Camera (Body Only) is an ideal camera for any level photographer; combining both high quality imaging power and a wealth of functions that enable you to create beautiful imagery with ease. This 18.0 megapixel DSLR features an APS-C-sized CMOS sensor and a DIGIC 5 image processor for fast operation and tremendous low light performance to an expanded ISO of 25600. A quickened 5.0fps continuous shooting ability and fast 9-point cross-type AF system are also supported by the performance of the DIGIC 5 processor. This combination of technologies also results in tremendous image quality with smooth color gradations and clarity for both images and videos.
Sunset Electronics Package Includes
Canon EOS T4i Digital SLR Camera
Canon EF-S 18-55mm f/3.5-5.6 IS Lens
Canon Zoom Telephoto 55-250 IS
Canon EF 50mm f1.8 II Autofocus Lens
2 Replacement LP-E8 Batteries
Battery Charger for Canon LP-E8
0.45x Wide Angle Lens
2x Telephoto Lens
3 Piece Pro Filter Kit (UV,CPL,FLD)
Gold Plated HDMI Cable
32GB Hi Speed SD Memory Card
Hi Speed SD Card Reader
Carrying Case
Tuplip Lens Hood
Table Top Tripod
LCD Screen Protectors
Cleaning Kit
Exclusive Sunset Electronics Cleaning Cloth


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Regular Board Meeting Agendas, Attachments and Minutes
The District Office is located at 721 Cliff Drive, Santa Barbara, CA. It is wheelchair accessible. The following services are available when requests are made by 4:00 p.m. of the day before the Board meeting: American Sign Language interpreters or use of a reader during a meeting; large print agenda or minutes in alternative format; assistive listening devices. Please contact the Office of the Superintendent/President at (805) 730-4011 if you need assistance in order to participate in a public meeting or if you need the agenda and public documents modified as required by Section 202 of the American with Disabilities Act.
The Office of the Superintendent/President, Room A 110 in the MacDougall Administration Center is the location where documents that are public records relating to any item under discussion on a Board agenda (including documents distributed with the agenda and those distributed to all or a majority of the members of the Board within 72 hours prior to a Board meeting) are available for public inspection.
7/14/2016 - Agenda and attachments
6/23/2016 - Agenda and attachments
6/23/2016 - Minutes
6/9/2016 - Agenda and attachments
6/9/2016 - Minutes
5/26/2016 - Agenda and attachments
5/26/2016 - Minutes
5/12/2016 - Agenda and attachments
>>Listen to the opening of the meeting
continues on video.
5/12/2016 - Minutes
4/28/2016 - Agenda and attachments
4/28/2016 - Minutes
4/14/2016 - Agenda and attachments
4/14/2016 - Minutes
3/24/16 - Agenda and attachments
3/24/2016 - Minutes
3/10/2016 - Agenda and attachments
>>Listen to meeting of 3/10/2016
3/10/2016 - Minutes
2/25/2016 - Agenda and attachments
2/25/2016 - Public Notice Energy Services Contract (posted 2/11/16)
2/25/2016 - Minutes
2/11/2016 - Agenda and attachments
2/11/2016 - Prioritized Supt/Pres Characteristics
2/11/2016 - Minutes
1/28/2016 - Agenda and attachments
1/28/2016 - Minutes
1/14/2016 - Agenda and attachments
1/14/2016 - Screening Committee Membership
1/14/2016 - The 3 Rs of Equitable and Effective Education
1/14/2016 - Minutes
Prior Years
Prior years have been Archived.
Please contact Angie Esqueda in the Superintendent/President's Office at 805-730-4011 or firstname.lastname@example.com for copies of prior years not yet posted or archived.


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We ate at Das Restaurant Wasserfall during our 2 week tour of Europe and it was our favorite meal of the whole trip! I am still craving the incredible pasta dishes that we ate there! We were looking for a restaurant close to our hotel and ran across this one on Trip Advisor. The food was absolutely exceptional and inexpensive for the quality. There were four of us in the group and 2 individuals got the seasonal pumpkin pasta and the other two ordered more traditional pasta dishes. Each one of the dishes was divine. I have been to many Italian restaurants in the US and in Italy and this was the best pasta that I have ever had. The amount of seasoning was perfect and the pasta literally melted in your mouth. The desserts were very yummy as well. I will return to this restaurant on my next visit to Salzburg.
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Business, Gadgets & Electronics, Telecom & Wireless
D.Phone Acquires 40% Stake In Guangzhou JinjiaxinChinese mobile phone retail chain D.Phone will invest CNY23.53 million to acquire a 40% stake in Guangzhou Jinjiaxin Communications.
Internet, Software, Telecom & Wireless
Chinese Firm Buys Into Mobile Game Data AnalyticsChinese mobile marketing platform Mobvista announced that the company will invest USD11.72 million to acquire a 90.01% stake in GameAnalytics, …
Internet, Telecom & Wireless
Tencent Grabs More Of Your Headspace In ChinaChina Music Corporation and Tencent Group joint announced that they have reached an agreement to implement a digital music business …
Internet, Telecom & Wireless
Hong Kong App Company Gains New InvestmentHong Kong is a financial mecca, but it has few well-funded powerhouse technology companies.
Business, Internet


text:
ZEUS-DO: A Design Oriented CFD-Based Unsteady Aerodynamic Capability for Flight Vehicle Multidisciplinary Configuration Shape Optimization
Award Information
Small Business Information
ZONA Technology, Inc.
9489 E. Ironwood Square Drive, Scottsdale, AZ, 85258-4578
Principal Investigator:
Ping-Chih Chen
Principal Investigator
(480) 945-9988
Principal Investigator
(480) 945-9988
Business Contact:
Jennifer Scherr
Business Official
(480) 945-9988
Business Official
(480) 945-9988
Research Institution:
AbstractCFD-based design-oriented (DO) steady/unsteady aerodynamic analysis tools for Aeroelastic / Aeroservoelastic (AE/ASE) evaluation lag significantly behind other multidisciplinary design optimization (MDO) developments for flight vehicle design. In practically all studies to date involving configuration multidisciplinary shape optimization, dynamic AE/ASE constraints were left out, thus, rendering the design results incomplete. Flutter, gust stresses, vibration, fatigue, ride comfort, handling qualities all extremely important still cannot be accounted for in an automated design process involving configuration shape variations. Proposed here is the creation of a comprehensive design-oriented CFD-based unsteady-aerodynamic methodology to enhance current flight vehicle shape MDO capabilities by the creation of AE/ASE shape sensitivities and efficient approximations tailored for large-scale design optimization. ZONA Technology's proven ZEUS code serves as the aerodynamic base for this development. In Phase II aerodynamic shape sensitivities for AE/ASE shape optimization will be developed for general 3D configurations made of lifting surfaces and bodies. The subsonic, transonic, supersonic, and hypersonic flight regimes will be covered. Integration with shape optimization finite-element structural codes will be demonstrated, covering diverse AE/ASE constraints including flutter and gust response. This new general capability will fit any aerospace vehicle MDO environment, and will provide a critically needed MDO building block.
* information listed above is at the time of submission.
An Official Website of the United States Government


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Kansas City Royals
Kansas City Royals news, rumors and injuries
Royals | Lorenzo Cain to rehab starting Friday
Tue, 26 Jul 2016 00:37:58 -0700
Kansas City Royals OF Lorenzo Cain (hamstring) will begin a rehab stint with Class AAA Omaha on Friday, July 29.
Fantasy Tip: This should put Cain back in the starting lineup in early August, at which point he should go into your lineup. He'll likely play every day upon return.
Comment () | Share: | Source: The Associated Press
Royals | Whit Merrifield, Jarrod Dyson out Monday
Mon, 25 Jul 2016 15:10:10 -0700
Kansas City Royals 2B Whit Merrifield and OF Jarrod Dyson are not in the starting lineup Monday, July 25. 2B Christian Colon is starting at second base and is hitting ninth, while OF Brett Eibner draws into right field and is batting eighth against Los Angeles Angels of Anaheim SP Hector Santiago.
Fantasy Tip: Colon should be a fantasy afterthought with his .250 average, no homer runs and nine RBI in 100 at-bats. Eibner has slightly more appeal as a deep sleeper in DFS and is hitting .254 with three bombs and 10 RBI. Neither project to stuff the stat sheet hitting low in the order, though.
Comment () | Share: | Source: Baseball Press
Royals | Edinson Volquez pitching well
Sun, 24 Jul 2016 16:20:48 -0700
Kansas City Royals SP Edinson Volquez allowed one run on seven hits while walking three and striking out three over six innings in a no-decision against the Texas Rangers Sunday, July 24, and he has posted a 2.87 ERA during the stretch.
Fantasy Tip: Volquez has been pitching well enough to use in AL-only formats, but he isn't a must-own player by any means.
Comment () | Share: | Source: The Associated Press
Royals | Lorenzo Cain expected to run
Sun, 24 Jul 2016 13:43:14 -0700
Kansas City Royals OF Lorenzo Cain (hamstring) was scheduled to do some running Sunday, July 24. Manager Ned Yost said Cain is close to starting a rehab assignment.
Fantasy Tip: Cain probably will need at least one week of rehab games before he is able to return to the starting lineup. He will be an everyday player once he returns from the injury and should be starting option in most fantasy leagues.
Comment () | Share: | Source: The Kansas City Star - Rustin Dodd
Royals | Salvador Perez receives day off
Sun, 24 Jul 2016 10:27:56 -0700
Kansas City Royals C Salvador Perez is not in the starting lineup against Texas Rangers SP A.J. Griffin Sunday, July 24. C Drew Butera will start at catcher and is batting eighth.
Fantasy Tip: Butera is hitting .306 with two home runs and nine RBI in limited playing time this season and can be a starting option in two-catcher leagues.
Comment () | Share: | Source: Baseball Press
Royals | Kansas City eyeing Clay Buchholz
Sun, 24 Jul 2016 08:34:05 -0700
The Kansas City Royals have expressed interest in Boston Red Sox P Clay Buchholz.
Fantasy Tip: Buchholz is 3-9 with a 6.10 ERA through 20 appearances (13 starts) and is currently pitching out of the bullpen. A change of scenery could be beneficial for his career but fantasy owners should take a wait-and-see approach to see how another club uses him if he is traded.
Comment () | Share: | Source: The Boston Globe - Nick Cafardo
Royals | Three-hit game for Paulo Orlando
Sat, 23 Jul 2016 21:29:31 -0700
Kansas City Royals OF Paulo Orlando went 3-for-4 with a run scored Saturday, July 23, against the Texas Rangers, raising his batting average to .323.
Fantasy Tip: Orlando has been a streaky hitter this season, and he is on another roll right now. Orlando has managed two or more hits in three of the past four games while hitting safely in nine of the past 11 outings. He is a must-start fantasy option in AL-only leagues, most rotisserie formats and DFS play at a mid-tier price.
Comment () | Share:
Royals | Cheslor Cuthbert keeps it going
Sat, 23 Jul 2016 21:28:32 -0700
Kansas City Royals 3B Cheslor Cuthbert went 2-for-3 with a double, two walks and a run scored Saturday, July 23, against the Texas Rangers to extend his hitting streak to 12 games.
Fantasy Tip: The Nicaraguan-born Cuthbert has come out of nowhere this season to emerge as a must-start AL-only fantasy option and a solid play in deeper mixed formats, too.
Comment () | Share: | Source: The Associated Press
Royals | Yordano Ventura dropped at home
Sat, 23 Jul 2016 21:26:25 -0700
Kansas City Royals SP Yordano Ventura allowed three earned runs, three hits and four walks with five strikeouts over five innings in a loss Saturday, July 23, against the Texas Rangers. He threw just 52 of his 89 pitches for strikes.
Fantasy Tip: Ventura is just 6-8 with a 4.99 ERA and 1.41 WHIP in 19 starts this season. He is only worth retaining in AL-only fantasy leagues and deeper mixed formats at this point, as he just hasn't shown any consistency this season.
Comment () | Share: | Source: The Associated Press
Royals | Yordano Ventura suffers rib injury
Sat, 23 Jul 2016 18:46:00 -0700
Kansas City Royals SP Yordano Ventura (rib) left his start against the Texas Rangers Saturday, July 23, after suffering a right rib contusion. X-rays came back negative.
Fantasy Tip: Ventura was injured after being hit by a line drive off the bat of 3B Adrian Beltre but is expected to make his next start against the Texas Rangers Thursday, July 28. He allowed three runs on three hits over five innings Saturday, with four walks and five strikeouts.
Comment () | Share: | Source: The Kansas City Star - Rustin Dodd
Royals | Whit Merrifield takes a seat
Sat, 23 Jul 2016 14:44:23 -0700
Kansas City Royals 2B Whit Merrifield is out of the lineup Saturday, July 23, with 2B Christian Colon hitting ninth.
Fantasy Tip: Colon is hitting .253 with nine RBI on the season, and he's not much of an option against Cole Hamels.
Comment () | Share: | Source: Baseball Press
Royals | Danny Duffy stifles Texas
Fri, 22 Jul 2016 20:47:39 -0700
Kansas City Royals SP Danny Duffy allowed one run on four hits while walking two and striking out four over 6 2/3 innings in a win over the Texas Rangers Friday, July 22.
Fantasy Tip: Duffy continues to post impressive numbers, and fantasy owners should feel comfortable using him against any matchup at this point.
Comment () | Share: | Source: The Associated Press
Royals | Lorenzo Cain's rehab pushed back
Fri, 22 Jul 2016 20:42:00 -0700
Kansas City Royals OF Lorenzo Cain (hamstring) had his rehab assignment pushed back to early next week, and manager Ned Yost said it was a case of leg fatigue and not a setback.
Fantasy Tip: Cain is a well-rounded fantasy weapon when healthy, so continue to stash him until he returns.
Comment () | Share: | Source: The Associated Press
Royals | KC interested in Nick Markakis
Fri, 22 Jul 2016 18:40:16 -0700
The Kansas City Royals have expressed interest in Atlanta Braves OF Nick Markakis. However, Atlanta would likely have to eat a portion of the $22 million he is owed through the 2018 season in order to make a deal possible.
Fantasy Tip: The 32-year-old Markakis was batting .260 with five home runs and 47 RBI through 94 games entering play Friday, July 22, and is a viable outfield option for single-universe fantasy leagues. With the Braves clearly in rebuilding mode, Markakis could be moved in order to give more at-bats to OFs Ender Inciarte and Mallex Smith.
Comment () | Share: | Source: MLB.com - Mark Bowman
Royals | Ian Kennedy roughed up by Tribe
Wed, 20 Jul 2016 16:52:12 -0700
Kansas City Royals SP Ian Kennedy endured one of his worst starts of the season Wednesday, July 20, versus the Cleveland Indians. He lasted just 4 1/3 innings, getting knocked around for seven runs on six hits, including a season-high four home runs allowed. Kennedy also struck out eight and walked one.
Fantasy Tip: Well, at least Kennedy was able to provide something for his owners with that strikeout total but other than that, this was a disaster of an outing. It was the third time this season the 31-year-old allowed seven runs, and it ended a streak of solid pitching, as Kennedy had allowed three runs or less in each of his last five outings. Hopefully he can bounce back his next time out.
Comment () | Share: | Source: USA TODAY Fantasy Sports
KFFL: Sports Link of the Day
Kansas City Royals Player News
KFFL: Sports Link of the Day


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The average journey time between Swansea and Reading Station is 2 hours 33 minutes. The fastest journey time is 2 hours 28 minutes. On an average weekday, there are 48 trains per day travelling from Swansea to Reading Station. The journey time may be longer on weekends and holidays.
Yes, it is possible to travel from Swansea to Reading Station without having to change trains. Use our journey planner above to get direct train times from Swansea to Reading Station.
The first train from Swansea to Reading Station departs at . The last train from Swansea to Reading Station departs at . No sleeper services are available. There may also be less services on weekends and public holidays; use the Journey Planner above to search for a specific train on your chosen travel date.
Find journey information for Reading Station to Swansea