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Co-Sourcing Improves Pharmaceutical Laboratory Productivity
Capitol Hill Critics Second-Guess Agencies Using...
Loss of Lives in Clinical Trials...
From our August issue: Clinical-Style Validation,...
Phase III trial data has demonstrated that treatment using the oral immunomodulatory candidate laquinimod leads to significant reductions in annualized relapse rates in patients with relapsing-remitting multiple sclerosis (MS), Teva Pharmaceuticals reports. The drug also led to significant reductions in disability progression, as measured by the Expanded Disability Severity Scale.
The pivotal placebo-controlled Allegro trial involved 1,106 MS patients in 24 countries, and evaluated the safety and efficacy of once-daily laquinimod in comparison with placebo. The primary efficacy outcome was the number of confirmed relapses. Secondary measures included confirmed disability progression and changes in MRI-evaluated active lesions.
Allegro was the first of two Phase III studies with laquinimod in MS patients. Results from the completed Bravo trial are expected during the latter part of 2011. This placebo-controlled trial in 1,332 patients compared the safety, efficacy, and tolerability of laquinimod therapy with treatment using interferon beta-1a. Laquinimod is separately undergoing Phase II development for the treatment of Crohn's disease and lupus nephritis.
Teva negotiated exclusive worldwide rights to develop, register, manufacture, and commercialize laquinimod from Active Biotech in 2004. Under terms of the deal Active received an up-front fee of $5 million, and could be eligible to development, regulatory, and sales milestones of $92 million, plus double-digit sales royalties. Teva is responsible for carrying out and funding all clinical development of the drug. Laquinimod received fast-track designation from the FDA in 2009.
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text:
Original Article
Detection of Clinically Relevant Pain Relief in Cats with Degenerative Joint Disease Associated Pain
Version of Record online: 10 FEB 2014
DOI: 10.1111/jvim.12312
Copyright © 2014 by the American College of Veterinary Internal Medicine
Journal of Veterinary Internal Medicine
Volume 28, Issue 2, pages 346–350, March/April 2014
Additional Information
How to Cite
Gruen, M.E., Griffith, E., Thomson, A., Simpson, W. and Lascelles, B.D.X. (2014), Detection of Clinically Relevant Pain Relief in Cats with Degenerative Joint Disease Associated Pain. Journal of Veterinary Internal Medicine, 28: 346–350. doi: 10.1111/jvim.12312
Publication History
- Issue online: 15 MAR 2014
- Version of Record online: 10 FEB 2014
- Manuscript Accepted: 26 DEC 2013
- Manuscript Revised: 20 NOV 2013
- Manuscript Received: 26 AUG 2013
Funded by
- Boehringer Ingelheim Vetmedica, Inc
- NIH. Grant Number: T32OD011130
- Abstract
- Article
- References
- Cited By
- Client-specific outcome measures;
- Degenerative joint disease;
- Osteoarthritis
Detection of clinically relevant pain relief in cats with degenerative joint disease (DJD) is complicated by a lack of validated outcome measures and a placebo effect.
To evaluate a novel approach for detection of pain relief in cats with DJD.
Fifty-eight client-owned cats.
Prospective, double-masked, placebo-controlled, stratified, randomized, clinical study. Enrolled cats were 6–21 years of age, with owner-observed mobility impairment, evidence of pain in at least 2 joints during orthopedic examination, and overlapping radiographic evidence of DJD, and underwent a 2-week baseline period, 3-week treatment period with placebo or meloxicam, and 3-week masked washout period. Outcome measures were evaluated at days 0, 15, 36, and 57.
Both groups significantly improved after the treatment period (day 36) on client-specific outcome measures (CSOM) and feline musculoskeletal pain index (FMPI) (P < .0001 for both); there was no difference between the groups on CSOM or FMPI score improvement. After the masked washout period, more cats that received meloxicam during the treatment period had a clinically relevant decrease in CSOM score (P = .048) and FMPI score (P = .021) than cats that received placebo.
Conclusions and Clinical Importance
Using both a client-specific and a general clinical metrology instrument, owners of cats with DJD were able to detect evident recurrence of clinical signs after withdrawal of active medication than after withdrawal of placebo, and that this study design might be a novel and useful way to circumvent the placebo effect and detect the efficacy of pain-relieving medications.


text:
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FerroHotel, Ragusa (province)
- Free WiFi and free parking
Main amenities
- 21 guestrooms
- Restaurant and bar/lounge
- Breakfast available
- Childcare
- 24-hour front desk
- Coffee/tea in a common area
- Front desk safe
- Meeting room
- Multilingual staff
- Free newspapers in the lobby
- Tour/ticket assistance
- TV in a common area
What's around
- Church of San Pietro (0.1 mi / 0.2 km)
- Castello dei Conti (0.2 mi / 0.4 km)
- Cathedral of San Giorgio (0.7 mi / 1.2 km)
- Ispica Cave (5.7 mi / 9.1 km)
- Old Portale di San Giorgio (9.2 mi / 14.7 km)
For families
- Babysitting or childcare
- Rollaway/extra beds available
- Refrigerator
- Hair dryer
- Elevator/lift
- In-room climate control (air conditioning)
FerroHotel, Ragusa (province)
Hotel Info: 866-539-8117from $67
- Superior Double Room Single Use
- Standard Double Room
- Standard Double Room Single Use
- Superior Double Room
- Quadruple Room
- Triple Room
Also popular with travelers from the USA
At a glance
Key facts
Hotel size
- This hotel has 21 rooms
- This hotel is arranged over 3 floors
- Check-in time starts at 2 PM
- Check-out time is 11 AM
- Express check-in/out
Required at check in
- Credit card or cash deposit required
- Government-issued photo ID required
Travelling with others
- Babysitting/childcare
- Pets allowed
- Restrictions apply *
Extra people
- Roll-away beds available, charges may apply*
- Free WiFi in public areas
- Free WiFi in rooms
- Free self parking
Nearby Four Star Ragusa (province) hotels
In the hotel
- Breakfast (surcharge)
- Restaurant
- Bar/lounge
- Room service (during limited hours)
- Coffee/tea in a common area
- One meeting room
- 24-hour front desk
- Tours/ticket assistance
- Free newspapers in lobby
- Multilingual staff
- Number of buildings/towers - 1
- Elevator/lift
- Safe-deposit box at front desk
- Television in common areas
In the room
- In-room climate control (air conditioning)
- Hair dryer
- Satellite TV channels
- Desk
- Free WiFi
- Refrigerator
Top Ragusa (province) hotels
Recently reviewed hotels in Ragusa (province)
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Special features
DiningTrack 4 - This restaurant specializes in regional cuisine and serves breakfast only.
FerroHotel, Ragusa (province)'s small print
Also known as
- FerroHotel
- FerroHotel Hotel
- FerroHotel Hotel Modica
- FerroHotel Modica
- FerroHotel Modica, Sicily
Cash transactions at this property cannot exceed EUR 2999.99, due to national regulations. For further details, please contact the property using information in the booking confirmation.
Pet-friendly rooms can be requested by contacting the property at the number on the booking confirmation.
Mandatory fees
You'll be asked to pay the following charges at check in or check out:
- A tax is imposed by the city: EUR 1.50 per person, per night, up to 7 nights. This tax does not apply to children under 18 years of age.
Optional extras
Breakfast is offered for an extra charge of EUR 7 per person (approximately)
We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.
Is the description of this hotel not correct? Tell us


text:
Release Date:
June 7, 2005
His unmistakable coonskin cap has served as a symbol of pioneer life for generations of adventurous youngsters, and now the story of frontiersman Davy Crockett comes to life as never before in this installment of the acclaimed children's series Shelley Duvall's Tall Tales and Legends. No one epitomizes courage quite like Davy Crockett, and whether facing down a bear or a giant comet, Davy always stick by his tried-and-true motto, "Make sure you're right, then go ahead." From wartime hero to beloved congressman, it seems that there's nothing Davy Crockett can't accomplish when he puts his mind to it, so why not join a legend in the making as one of America's greatest folk heroes sets out on the journey of a lifetime? ~ Jason Buchanan, Rovi
- Genre: Kids and Family
- Category Family-Oriented Adventure
- Studio: Koch Vision
- Run Time: 50 min
- Language: English
- Release Date: June 7, 2005
other Info.
- Online Item #: 11522404
- Store Item Number (DPCI): 246-03-0753
- Made in the USA or Imported


text:
|Publication number
|Publication type
|Application number
|Publication date
|Aug 9, 1994
|Filing date
|Nov 13, 1992
|Priority date
|Nov 13, 1991
|Fee status
|Publication number
|Yuuji Kuriyama, Shoji Sakaida, Hikaru Ando, Masao Ando, Kazumi Ichimaru, Kazutoshi Sakamoto
|Original Assignee
|Toyoda Gosei Co., Ltd.
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (9), Referenced by (39), Classifications (6), Legal Events (3)
|External Links: USPTO, USPTO Assignment, Espacenet
1. Field of the Invention
This invention relates to an air bag device. More particularly, this invention relates to an air bag device being equipped in a vehicle instrument panel.
2. Description of Related Art
A cover of an air bag device is generally fixed to an opening for an instrument panel, and has a hinge or a break-away portion as described, for example, in U.S. Pat. No. 5,096,221 and Japanese Utility Model JIKKAISHO 63-111353.
However, by use of the hinge or breakaway portion, the number of composite parts increases, and it requires much time and labor to install these parts to the cover.
An object of the present invention is to provide an air bag device wherein a cover is easily fixed to an opening of an instrument panel, and is lighter in weight because of a reduction in the number of the composite parts of a hinge or break-away portion.
Another object of the present invention is to provide an air bag device for which a cover opens smoothly.
Other objects, features, and characteristics of the present invention, as well as the methods and operation and functions of the related elements of the structure, and to the combination of parts and economies of manufacture, will become apparent upon consideration of the following description and the appended claims with reference to the accompanying drawings, all of which form a part of this specification, wherein like reference numerals designate corresponding parts in the various figures.
FIG. 1 shows a cross-sectional view of an air bag device according to a first embodiment of this invention.
FIG. 2 shows a cross-sectional view of an air bag device according to the second embodiment of this invention.
FIG. 3 shows a partial perspective view of an air bag device according to the second embodiment of this invention.
As shown in FIG. 1, an air bag device 10 is equipped in an instrument panel 12, for example on the passenger side of the front seat of a vehicle. A case 16 including an air bag 14 and an inflator 58 is fixed to a body (not shown), and a cover 26 is held at an opening 24 of a surrounding wall 18 of the case 16. The cover 26 includes a base portion 28 and a surface layer 34 and has an "L" shaped cross-section the lower leg of which includes bracket 30.
The base portion or layer 28 is made of TPO (thermoplastic olefin). The base portion may be made of PPF (fiber reinforced polypropylene), polyester, polymer alloy material of PPO (polyphenylene oxide) and polyamide or polyethylene. The surface layer 34 includes an outer skin layer 36 made of TPO and an inner sponge layer 38 made of PP (polypropylene). The skin layer 36 may be made of PVC (polyvinyl chloride) or urethane, and the sponge layer 38 may be made of PVC foam or urethane foams. From an adhesive point of view, when the sponge layer 38 is made PP foam, the material of the base portion is preferably PPF or TPO. When the sponge layer 38 is made of PVC foam, the material of the base portion 28 is preferably polyester.
A hinge 40, which extends the full length of cover 26 and forms a rotation axis for cover 26 when air bag 14 is inflated, is integral with bracket 30 of the cover 26. The hinge 40 is a semicircular or inverted U-shape hump portion. The base portion 28 and net 42 also of inverted U-shape at the hinge fit into a recess formed by removing at least a portion of the sponge layer 38 at the hinge hump portion. A net 42 made of polyamide (6 nylon) is partially embedded in the base portion 28. The net 42 reinforces cover 26 throughout as well as hinge 40 and prevents destruction of the hinge when the bag is inflated. Net 42 also reinforces bracket 30. Bracket 30 also has fixing holes 32.
Break away portion 44 is connected to the cover at the side opposite hinge 40. The break-away portion 44 is made of synthetic resin like a polyester so as to be breakable easier than the material of the base portion 28, and includes a flat flange portion 46 inserted in the base portion 28, a neck portion 48 extending from the flange portion 46, and a fixing portion 52 having a fixing hole. The neck portion 48 has a thin portion 50 in order to be breakable. The break-away portion 44 is made of TPO (Sumitomo TPE 3885). As examples, the tensile strength of the break-away portion 44 is 95Kg/cm2, and that of the base portion 28 (made of TPO: Sumitomo TPE 3255) is 200Kg/cm2 by tensile test according to JIS K 6301/No. 2 Dambel 50 mm/min tensile speed.
At hinge 40, the cover 26 is fixed to the case 16 by any convenient means, such as, for example, screws 54 which engage with holes 20 in wall 18 through the fixing holes 32 of the bracket 30. On the opposite side of the case, adjacent break-away portion 44, the cover 26 is fixed with screws 56 to the fixing portion 22 through the fixing portion 52, and is disposed to close the opening 24.
The cover 26 is produced as follows. The surface layer 34 is vacuum molded to the shape of the cover 26. The surface layer 34 is arranged, together with the net 42 and the break-away portion 44 in a mold which molds the base portion 28. The base material 28 is produced by a stamping mold or injection mold.
The air bag device 10 is installed in the vehicle after the cover 26 is fixed to the case 16 which contains the folded air bag 15 and the inflator 58. In the air bag device 10, the air bag 14 is deployed by the gas from inflator 58, and the break-away portion 44 is broken at the thin portion 50 by the deployment force of the air bag 14, causing cover 26 to open rotationally around hinge 40. Since the break-away portion 44 is connected as an insert in the synthetic resin cover 26 and is secured in place at the same time as the molding of cover 26, there is no need to use screws to fix the break-away portion 44 to cover 26, and the number of parts can be reduced. Besides, as the break-away portion 44 is made of a material having a strength lower than that of the base portion 28, the break-away portion 44 easily breaks at the time of deployment of the air bag 14. The break-away portion 44 is easily configured and constructed by selecting the material or shape freely.
In the above-described embodiment, cover 26 is fixed to the surrounding wall 18 of case 16; however, hinge 40 of cover 26, and/or the break-away portion 44 may be connected to the instrument panel 12. FIG. 1 shows the flange portion 46 as having a flat shape; however, the flange portion 46 may be changed to an inverted U-shape or the flat shape may have holes which fill with the material of base portion 28 for tighter connection to the base portion.
As shown in FIGS. 2 and 3, an air bag device 110, disposed in an upper portion of an instrument panel 112 in front of a passenger, includes a case 116 made of metal sheet and having an inflator 158, and a cover 126 over an opening 117 of the case 116. The cover 126 which is disposed in an opening 124 of the instrument panel 112 has a base portion 128 and a surface layer 134 and has an "L" shaped cross-section, the lower leg of which includes bracket 130.
The surface layer 134 includes an outer skin layer 136 and an inner sponge layer 138 which is bonded to the outer layer 136. At a side portion, cover 126 has a hinge 140 which forms a rotation axis for cover 126 when air bag 114 is inflated. Throughout cover 126 has a reinforcing net 142 made of polyamide (6 nylon) embedded in the base portion or layer 128. As shown, cover 126 has an extended portion which extends beyond hinge 140 (to the left in FIG. 2) away from case opening 117.
Bracket 130 extends from hinge 140 and both are covered by net 142. The bracket 130 has fixing holes 132. Case 116 has a bottom portion having a half columnar shape at the lower portion where an inflator 158 is installed and a rectangular-shaped upper portion having an opening portion 117.
A folded air bag 114 is disposed over the inflator 158. At the bottom, case 116 has a fixing bracket (not shown) by which case 116 is secured to a body (not shown). The case 116 has a sloped or angled wall member 119 narrowing the opening 117 at the side or end wall 118 near the hinge 140, and a channel member 160 made of metal sheet is fixed along the hinge 140 by spot welding or the like. The channel member 160 is "L" shaped in cross-section, having an upper leg 162 and a side leg 164, and legs 162, 164 have respective fin portions 166, 167 welded to the wall member 119.
Bolts 154 which pass through the fixing holes 132 are welded to the side leg 164. The cover 126 is connected to the side wall 118 by the slot 154 and a nut 155 with a fitting plate 168.
Channel member 160 is fixed to wall member 119 so that a space 169 exists between the channel member 160 and the hinge 140.
When the air bag 114 inflates, cover 126 deploys rotationally around hinge 140. If case 116 were allowed to deform, hinge 140 would also deform (bend) and that would prevent cover 126 from opening smoothly. Deformation of case 116 and hinge 140 is prevented, because channel member 160 reinforces wall member 119. When air bag 114 inflates, the base portion 131 of bracket 130 deforms (bends backward) and prevents concentration of stress in hinge 140 because of space 169 between the channel member 160 and hinge 140. Therefore, the rotation axis X--X (FIG. 3) of the cover 126 is maintained linear and stable, and the cover 126 can be opened smoothly.
This embodiment shows wall member 119 reinforced by channel member 160; however, channel member 160 may be connected to the vertical side wall 118 if there is no sloped portion. As there is a space 170 under the position between the hinge 140 and the edge portion 127, cover 126 would rotate smoothly around hinge 140.
While the invention has been described in connection with what is presently considered to be the most practical and preferred embodiments, it is to be understood that the invention is not to be limited to the disclosed embodiments, but on the contrary, is intended to cover various modifications and equivalent arrangements included with the spirit and scope of the appended claims.
|Cited Patent
|Filing date
|Publication date
|Nov 2, 1979
|May 4, 1982
|Daimler-Benz Aktiengesellschaft
|Downwardly foldable covering for a gas cushion
|Jan 13, 1988
|Jun 27, 1989
|Toyota Jidosha Kabushiki Kaisha
|Air bag door fastening structure
|Sep 8, 1988
|Jan 16, 1990
|Tip Engineering Group, Inc.
|Closure for an air bag deployment opening
|Aug 22, 1990
|Nov 19, 1991
|Davidson Textron Inc.
|Instrument panel with airbag deployment door
|Feb 21, 1991
|Mar 17, 1992
|Davidson Textron Inc.
|Air bag door with plural substrates
|Jan 7, 1992
|Oct 27, 1992
|Mayco Plastics, Inc.
|Closure for vehicle trim
|Jun 17, 1991
|May 11, 1993
|Honda Giken Kogyo Kabushiki Kaisha
|Vehicle occupant protection air bag module
|Aug 30, 1991
|Apr 2, 1992
|Toyota Motor Co Ltd
|Oeffnungseinrichtung einer luftsackabdeckung in einem fahrzeug
|Title not available
|Citing Patent
|Filing date
|Publication date
|Mar 14, 1995
|Jul 16, 1996
|Davidson Textron
|Method of manufacturing a trim panel having an air bag door
|Dec 19, 1994
|Aug 13, 1996
|General Motors Corporation
|Supplemental inflation restraint and door arrangement
|Mar 31, 1995
|Oct 15, 1996
|Davidson Textron Inc.
|Motor vehicle instrument panel with flexible tethering hinged air bag deployment door
|Aug 1, 1995
|Mar 11, 1997
|Trw Vehicle Safety Systems Inc.
|Deployment apparatus for an inflatable vehicle occupant restraint
|May 16, 1995
|Mar 25, 1997
|Morton International Inc.
|Break-away fastening system for air bag deployment doors
|Mar 29, 1996
|Feb 10, 1998
|Toyoda Gosei Co., Ltd.
|Skin-covered lid
|Apr 21, 1995
|Sep 8, 1998
|Davidson Textron Inc.
|Method of forming a motor vehicle instrument panel with a flexibly tethered air bag deployment door
|Aug 1, 1996
|Oct 6, 1998
|Textron Automative Company, Inc.
|Trim panel having air bag door
|Aug 8, 1997
|Aug 24, 1999
|General Motors Corporation
|Air bag cover door with tether
|Jul 10, 1997
|Nov 2, 1999
|Davidson Textron Inc.
|Motor vehicle instrument panel with flexible tethering hinged air bag deployment door
|Sep 10, 1997
|Mar 21, 2000
|Trw Occupant Restraint Systems Gmbh
|Gas bag cover
|Feb 17, 1998
|Oct 17, 2000
|Trw Occupant Restraint Systems Gmbh
|Knee restraint device for vehicles
|Aug 26, 1996
|Dec 26, 2000
|The Goodyear Tire & Rubber Company
|Instrument panel passenger side air bag door
|Mar 12, 1999
|Nov 20, 2001
|Sommer Allibert-Lignotock Gmbh
|Instrument panel for a motor vehicle
|Jul 31, 1998
|Oct 8, 2002
|Textron Automotive Company, Inc.
|Method of forming a motor vehicle instrument panel with a flexibly tethered air bag deployment door
|Jul 18, 2001
|Jul 22, 2003
|Faurecia Industries
|Motor vehicle equipment for airbag, corresponding assembly and method for manufacturing it
|Sep 23, 2003
|Aug 22, 2006
|Nihon Plast Co., Ltd.
|Cover body for air bag apparatus
|Mar 19, 2003
|Oct 17, 2006
|Delphi Technologies, Inc.
|Cover for airbag module and method of making
|Jul 6, 2006
|Jun 12, 2007
|Nihon Plast Co., Ltd.
|Cover body for air bag apparatus
|Feb 23, 2010
|Amsafe, Inc.
|Inflatable personal restraint systems and associated methods of use and manufacture
|May 4, 2007
|Aug 10, 2010
|Nihon Plast Co., Ltd.
|Cover body for air bag apparatus
|Jul 19, 2011
|Amsafe, Inc.
|Inflatable personal restraint systems having web-mounted inflators and associated methods of use and manufacture
|Jul 29, 2011
|May 14, 2013
|Amsafe, Inc.
|Inflator connectors for inflatable personal restraints and associated systems and methods
|Apr 13, 2011
|Jun 25, 2013
|Amsafe, Inc.
|Stitch patterns for restraint-mounted airbags and associated systems and methods
|Mar 19, 2012
|Sep 3, 2013
|Amsafe, Inc.
|Structure mounted airbag assemblies and associated systems and methods
|Jun 23, 2011
|Nov 26, 2013
|Hyundai Motor Company
|Door hinge structure for passenger airbags
|Oct 2, 2014
|May 31, 2016
|Amsafe, Inc.
|Active positioning airbag assembly and associated systems and methods
|Aug 29, 2014
|Jul 12, 2016
|Faurecia Innenraum Systeme Gmbh
|Lining part for mounting on a vehicle body part with an airbag module, airbag system with a body part and with such a lining part and method for the production of the lining part
|Mar 19, 2003
|Dec 25, 2003
|Schenck David P.
|Cover for airbag module and method of making
|Sep 23, 2003
|Mar 25, 2004
|Nihon Plast Co., Ltd.
|Cover body for air bag apparatus
|Jul 6, 2006
|Nov 9, 2006
|Nihon Plast Co., Ltd.
|Cover body for air bag apparatus
|Dec 12, 2005
|May 10, 2007
|Hyundai Motor Company
|Airbag door structure for vehicular passenger seat
|May 4, 2007
|Sep 6, 2007
|Nihon Plast Co., Ltd.
|Cover body for air bag apparatus
|Jun 23, 2011
|May 3, 2012
|Hyundai Motor Company
|Door hinge structure for passenger airbags
|Aug 29, 2014
|Mar 5, 2015
|Faurecia Innenraum Systeme Gmbh
|Lining Part for Mounting on a Vehicle Body Part with an Airbag Module, Airbag System with a Body Part and with Such a Lining Part and Method for the Production of the Lining Part
|Apr 24, 2015
|Aug 13, 2015
|Johnson Controls Technology Company
|Airbag deployment system for a fabric wrapped vehicle interior planel
|Jun 2, 2001
|Jan 2, 2002
|Bayerische Motoren Werke Aktiengesellschaft
|Passenger airbag cover
|Mar 8, 1996
|Oct 3, 1996
|Davidson Textron Inc.
|Motor vehicle instrument panel with flexible tethering hinged air bag deployment door
|May 22, 1997
|Jan 8, 1998
|Georg Kaufmann
|Process and device for making movable units of a plastic component
|U.S. Classification
|280/728.3, 280/732
|International Classification
|Cooperative Classification
|European Classification
|Jan 12, 1993
Owner name: TOYODA GOSEI CO., LTD., JAPAN
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNORS:KURIYAMA, YUUJI;SAKAIDA, SHOJI;ANDO, HIKARU;AND OTHERS;REEL/FRAME:006417/0524
Effective date: 19921225
|Aug 9, 1998
|Lapse for failure to pay maintenance fees
|Oct 20, 1998
|Expired due to failure to pay maintenance fee
Effective date: 19980809


text:
Maritime Today
The Maritime Industry's original and most viewed E-News Service
Elomatic Ltd and Deltamarin Ltd have signed a tri-party engineering contract with shipbuilder MV Werften for the design of Star Cruises' new Global Class "mega passenger ship,
In the next few years, demand for bandwidth on the high seas will grow, in no small part due to technology that is making operations more efficient and keeping crews and passengers healthy,
Bored with palm-fringed beaches and turquoise seas? Then the gigantic oil platforms of the North Sea beckon. The first ever "rig-spotting" cruise just ended off the coast of Norway,
The Athens, Greece-based Safe Bulkers Inc. (SB) has reported a loss of $9 million in its second quarter. It had a loss of 15 cents per share.
Net revenue for Q2 of 2016 decreased by 18% to $26.
Owners anchoring ships rather than fix at low rates. W. Australia-China capesize rates hit over two-month low.
Freight rates for large capesize dry cargo ships
USA-Monaco based bulk carrier Scorpio Bulkers has reported a loss of $24.7 million in its second quarter of 2016, pushing the carrier's deficit up to $ 83 million.


text:
"Shelly" and her family sat down to dinner when the phone rang. Before she answered the call, Shelly looked at the caller ID and saw her own name and phone number! She answered the call and heard a recording that offered to lower her credit card interest rate. Shelly hung up and reported the call to her phone company.
At the first Senate E-12 Education Policy and Budget Committee hearing of the year, members heard dozens of great recommendations on everything from technology to school facilities to mental health. As Chair of the committee, I felt we needed to hear from our education partners and stakeholders to begin session with a clear idea of what's needed in our public schools across the state.
$2090. That's the amount of money my deceased grandma had in an old TCF bank account that none of us knew about until I checked the State of Minnesota's unclaimed property list.
Did you know the State of Minnesota is holding over $606 million in unclaimed property? This averages out to about $120 per person for each of Minnesota's roughly five million residents.
With the state in the midst of a particularly tough influenza season, health officials are urging Minnesotans to protect themselves and others by staying home when they are ill.
Thirteen years ago last week from a high school in southwestern Ohio, Pre
Now that the holidays are upon us, many people dream of taking a tropical vacation or spending time near a popular attraction. If you're shopping for a getaway, you may have considered a timeshare, an arrangement that generally gives you the right to stay at a certain property for a specified amount of time each year. There are more than 1,500 timeshare resorts in the United States, according to the American Resort Development Association, and the average sales price for a unit is more than $20,000. If you're thinking of spending your free time at one of them, the Minnesota Society of CPAs offers this advice.
I've always said producing a newspaper would be easier if I could just make up the news. And every Christmas, I prove myself right.
Last week I sent out this year's edition of the Bromley Blab. It's a family Christmas newsletter written in the style of The Onion. For example, one year a story about my son was headlined, "Drew: Penn State or state pen?"
What's beautiful about the Blab is that I get to make everything up. Sure, all the news stories are based on fact, but as reporter/editor/publisher/circulation manager, I'm allowed to take liberties. This is a fun change from my day job, which frowns on the fabrication of quotes by made-up sources.
As shoppers start making their holiday lists, the Minnesota Department of Commerce reminds families to stay vigilant about toys and product safety.
Shoppers should check recall lists and use common sense, selecting age-appropriate toys, observing manufacturer's warnings regarding safety hazards, and monitoring use when necessary.
A selection of toy and child product recalls, numbered by date, include:
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North St. Paul, MN 55109
Phone: (651) 777-8800
Fax: (651) 777-8288
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photography in grenada
Jun 21, 2012
i will be holidaying in grenada for a week at the beginning of july and will be keen to explore the photographic possibilities there. will take my usual travel kit of nikon d300, 17-50 vc, 70-300mm vr and fisheye.
i'd be grateful for any hints and tips anyone has to offer about photo opportunites on grenada. my only real matter of concern is the effect of humidity on my gear if we visit the central jungle area. how bad is this at the this time of year, am i likely to need to take any special precuations?
any replies appreciated.
djwuk's gear list:djwuk's gear list
Olympus Tough TG-2 Nikon D200 Nikon D300 Nikon D7200 Nikon AF DX Fisheye-Nikkor 10.5mm f/2.8G ED +7 more
Nikon D300
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My poor baby is only level 35. Haven't visited her for 5498123468 years, my gosh. Her outfit is even worse.
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Posted on 11 April 2013
- 08:26
It was the final preparation for tonight's Europa League quarter-final, second leg against the Swiss champions. Kick-off is 9.05m local time, 8.05pm UK.
As usual, Fitness Coach Jose Mario Rocha took care of the warm-up before Andre Villas-Boas and the coaching staff put the squad through a number of football exercises, ending in a match over half the pitch.
There was a Spurs legend in the stadium as well - Martin Chivers, third in our all-time goalscoring list and our top European marksman.
30 May 2016
With the deadline looming for international bosses to name their final 23-man squads for Euro 2016, a number of our players have been working hard as usual in training over the Bank Holiday weekend.
9 March 2016
The players stepped into the impressive Signal Iduna Park for the first time for training this evening (Wednesday, March 8).
29 February 2016
The players returned to the Hotspur Way training pitches today (Monday, February 29) after getting the better of Swansea City at White Hart Lane on Sunday.
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Staff Council (brochure.pdf) serves as the voice for staff at Carnegie Mellon University through policy advocacy and community involvement, providing an organization that enables staff to realize their full potential and impact their quality of life. The chief purpose of Staff Council is to examine matters related to all staff, and to formulate recommendations to the university administration. The responsibility of Staff Council is to represent all persons holding full- or part-time staff appointments at Carnegie Mellon who are not represented by the faculty organization or a bargaining unit.
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Welcome to BaseNav
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Definición de digital en inglés:
1(Of signals or data) expressed as series of the digits 0 and 1, typically represented by values of a physical quantity such as voltage or magnetic polarization. Often contrasted with analogue.
Oraciones de ejemplo
- The digital signal is converted back to an analog one when it reaches its destination.
- The receiving modem translates the analog signals back to digital form.
- Boxes are required to translate the digital binary code back to analog signals for viewing.
1.2Involving or relating to the use of computer technology: the digital revolution
Más ejemplos en oraciones
- On top of this, this whole situation elevates the issue of computer security and thus Internet technology and the digital world.
- With technologies merging and the digital revolution moving in, a closer look at movie-making seems timely.
- Readers have remarked before how some digital technology mavens merely acquire, and never seem to listen to what they hoard.
2(Of a clock or watch) showing the time by means of displayed digits rather than hands or a pointer.
Oraciones de ejemplo
- Is it coincidence that our generation is infatuated with digital watches and clocks?
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3Relating to a finger or fingers.
Oraciones de ejemplo
- The saphenous sometimes provides the medial dorsal digital nerve to the great toe.
- Fifteen percent of colorectal cancers can be detected by digital rectal examination.
- Biopsy rates reflect the intensity of screening with digital rectal examinations as well as prostate specific antigen.
Late 15th century: from Latin digitalis, from digitus 'finger, toe'.
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Thanks for the compliments everyone ,,,fun to show her off! I took down the pics now, as I get nervous about them getting lost out thereĀin eternal BBC cyber-space Ā....Happy Mother's Day!
My Princess
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Beautiful!!! :))
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CD'ing, BF'ing SAHM
Ahhh Thanks ...September, I feel FAR from "hot stuff" (the hat hides a lot, ha ha!) ...I've been telling my Dh that we have to do something to make sure Katharine isn't embarrassed later because her parents "look" so old (we ARE old ...I'm gonna be 42 in June ~ ACK!!) ...it was fun to get dressed up for the Tea Party though! And Katharine is so much fun to dress-up too ...
PS ...I won't keep the pics up for long, just long enough to show Katharine off!
She is getting so big and is just as beautiful as ever.
Liz mom to 5 great kids-Andrea 18yrs, Lea 16yrs, Dominick 13yrs, Bella 9yrs and Benjamin 6yrs.
Married 18yrs to my Brian-I am a twin!
So precious!┬Ā She looks like a china doll!
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mom to B (9/2008) and C(6/2011)
MC 6.7.2010 **always in my heart**
Proud Mommy to my twin boys (J & B)
Blessed beyond measure to be a wife and mother...
Gorgeous, the pair of you! And nine weeks already... Wow...
And "old," my arse. *pfffft* Almost-42 is faaaar from old, woman! And, yes, just accept it: you're gorgeous.
padawan #1 via IVF: Steven, 3/2006
padawan #2 via adoption: Eliza, 6/2016
adoption process started 2/2014; homestudy approved 6/2014; matched 6/22/2016 @ 9 days old - IT'S A GIRL!; placed 6/28/2016
Jaime, mom to Norah ('06), Lucy ('08) and Henry ('11). Baby #4 due mid-August 2016 - it's a girl!
OOOhhhh......KATHARINE is indeed a Princess!!! I┬Ā would expect nothing less!!!┬ĀShe really has the biggest blue eyes......from you GINA??? You are looking good too momma...you both "sparkle"......┬Ā
P.S.I had my last babe when I was pushing forty & was always the oldest of his classmate's moms. But it kept me young┬Ā & "in tune" with┬Ā the times!!!!!┬ĀYou will never be an embarrasment to any of your kiddos...trust me!!!
Glad all seems to be going well for you & the family!!!
Mom to "M" ( 1974), "C" ( 1976), "A" (1985) & "Glamma" to "C" ('2007) & "M" ('2010) & "J" (2012)


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Smells problem
1999 Cadillac Catera 6 cyl Two Wheel Drive Automatic 13500 miles
dEAR Sir
my car smell like gas. I have had a new fuel pump put on. If the car is running and standing still, the fumes are really bad. What could it be
Tuesday, September 8th, 2009 AT 12:27 PM


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Top Definition
When you get punched so hard in the stomach you fart
Veronica walked up to Jenna and gave her a (punch fart) in the gut causing an audible fart to come from Jenna's rear-end.
af Girlygoo 26. januar 2012
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My girlfriend's Neon has a very common issue. She and I are driving along and out of nowhere, the whole intrument panal dies. Every guage is inoperational for about a minute then it all becomes operational again. It's very random and irritating. It's not just the speedometer, its the whole panal. The battery is new and I have checked the fuse. What must I do to fix this?
I also have another question, the car is due for an emissions test and the tabs are long over due because it sat for years, with the new battery the computer had been reset. How do I need to drive it to reset it and how long do you recommend?
Saturday, May 5th, 2012 AT 5:40 PM


text:
Infectious - Beethoven Remix
Credits & Info
- Uploaded
- Jun 30, 2010 | 8:27 PM EDT
- File Info
- Song
- 1 min 1 sec
- Score
- 1.00 / 5.00
Related Content
You might also enjoy:
Licensing Terms
You may not use this work for commercial purposes without making specific arrangements with the artist UNLESS your work is a web-based game or animation, in which case you may use this freely.
- Score:
- Rated 1.00 / 5 stars
- Plays & Downloads:
- 7,029 Plays | 113 Downloads
- Share Links:
- Genres:
- Hip Hop, Rap, R&B - Hip Hop - Modern
- None
Author Comments
Rated 2.5 / 5 stars
I smell a troll, a big fat white-ass troll.
Rated 5 / 5 stars
RE-MIX! Owah!
Something about cereal
*I couldn't hear this part because I was laughing too hard about the last line*
Delicious and nutritious or something
People taste me 'cause I'm infected
Motherfuckin' curb stompin' mother fuckah
After that part i got bored and played Monopoly.
Rated 0 / 5 stars
Beethoven is now rolling in his grave because of this, regardless of him being dead and deaf. You've ruined his name entirely. This is horrible.
Rated 5 / 5 stars
Oh my god.
This is seriously the best thing I have heard in a long, LONG time. This is fuckin' hilarious.
Rated 5 / 5 stars
Hilarious. That is all. Its not good music, its not good rap, its not good lyrics. Its just hilarious.
10*'s for honey bunches of oats, cuz it is very tasty.


text:
First of all, great work indeed. Well done.
For the macro shots, were these at night, or just selective lighting during the day? If so, what where you using for lighting? And for stabilization?
Also, perhaps I'm misremembering, but did you not use to shoot a Canon 1DC before? If so, do you have any thoughts about the differences/similarities between shooting with the two different cameras? Especially when it comes to 4k quality, white balancing, etc.
Thanks Andrei for watching it.
You have it mistaken on the camera. I have always used the 5d. The 1dc was always something I wanted but the price was so out of reach, I was never able to do it. There are good thing and bad things comparing the cameras. Shooting at 60p requires a lot more light than I thought it would. So I ended up shooting much higher ISO than I did on the 5d. Also the crop factor with 4K. I was unable to get the larger critter in with the 100mm. Where shooting with a full sensor 5d I was able to do it. Of course this helped me get the smaller critters better. So it was a trade off. Wb process is easier with the 1dxII, however, actually getting a good wb might be harder. I only did 2 dives with it, and the sites were nots great with poor viz. I should beget a better feel when I go to the Solomon's in July. The dual pixel autofocus of the new camera, is mixed. It helped with some shots, but most of the time the focus hunting would ruin a shot. It's not totally worthless, you just have to get the right situation. Of course I may need to learn how to use it better too.
As for the shooting, yes it is selective lighting, and the ambient light needs to be low. The cuttlefish was in the late afternoon, and deeper. the red fish was at night. I use the solas, 2100 and 8000's to light up a scene if needed. I also tried out the inon lf800n. That has 5 degree beam. As for stability. I use a tripod. Xit404.
Hope that helps.
- dreifish likes this


text:
Jainson Hotel, Mumbai
124,Jain Laxmi Mansion Opposite Navjivan Society Lamington Road, Mumbai
Ranked 862 amongst 1199 hotels in Mumbai
Jainson Hotel Reviews
Best hotel in the world, i have ever seen. I stay there in june 2015 and i enjoyed it very much with my wife. I suggest everyone to go there and enjoy the beach of goa. The hotel have its class originally, very nice staff and coordinating.
"Far from airport, poor room maintenance, good food"
Hotel location was convenient so it was easy to reach there. It was located at 5 mins walking distance from railway station and 15 mins away from bus stand but it was very far from Airport. Inside and outside look of the hotel was okay. It was moderate. Room was not much spacious but well-maintained. Everything was clean there. TV and AC were provi....Read More
"Relax stay with neat rooms, humble staff"
It was relaxing, the staff was courtesy, the approach to the hotel is easy, the meals served in the restaurant were good. The room was neat, clean and fresh. Services provided were excellent. Staff handled request humbly, the entire experience was warm. We would definitely like to revisit the resort and spend our holidays in such a comfort and rela....Read More
Hotel Jain Sons is a small hotel, opposite to Navjiwan Society on Lamington Road, Mumbai Central. It has small rooms with common bathroom or AC rooms with attached bath. The rates are economical, with just basic facilities only. However they have their own eatery on ground floor itself, which sell tea, milk, curd and snacks in a clean environment.
Featured in the HolidayIQ Blog
Authentic Gujarati Food At Shree Thaker Bhojanalay
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Pav Bhaji at Sardar's
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Are you the business owner of Jainson Hotel, Mumbai ?
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Hurry up and claim your property now!Manage your listing > Get more reviews for your property >


text:
I will try to list this as pros and cons. Every person has specific likes and dislikes and I like it when I am just given the facts.
Very beautiful grounds, beautiful pool. The condo is modern with good appliances. Located close to everything. They have the best scuba operation on the island.
Our first night we were kept up by a live band playing until 11pm. For a family resort ,a questionable idea. Then we were woken several more times by a screaming woman. The 2nd night we were woken at 3am and 345 am by loud arguing and talking. I called every time this happened and it only helped a little. I asked for the front desk manager to call me after the first night and the general manager the 2nd night. I was told the general manager was at lunch and couldn't be found, he never called me back. I guess lunch was more important than clients. The front desk tried to convince me this noise was from the beach and they had no control over it. Both times, I looked out and the people were in the resort, by the pool.
The ocean front view that we paid for was actually a palm tree view. I have pictures, the only thing you could see from our balcony was the palm trees, you can't see the ocean at all. THIS IS AN OCEAN FRONT CONDO, WITH A VIEW OF PALM TREES!!!
We were not told that our condo would be so loud or next to party central, nor were we told we wouldn't be able to see the ocean from our "ocean front" room.
Service was inconsistent-at times it was great, other times I would call for something and they would never get back to me.
I tried one more time to contact the management but to no avail. They seem to try to placate you and hope the problem goes away.
With all of this, I would still go back. However, I would strongly check out where the room is and what the view is. They seem to not really care about guest happiness. I think this is because they are currently the best option on Roatan and always full, so they don't have to worry if the guests are happy or not.
- Official Description (provided by the hotel):
- Location: West Bay Beach, Roatan, Bay Islands, Honduras, Central America (15 minutes from airport). Accommodations: Condo, 2 Bedrooms + Convertible bed(s), 2 Baths (Sleeps 4-6)Keywords: Luxurious Condo Resort 2BR/2BA at Infinity Bay Roatan. Planning a vacation now to leave in the fall? Location Location Location. The most beautiful upscale resort which is called Infinity Bay Resort located at West Bay Beach, which is one of the top beaches in Roatan, Honduras and of the Caribbean. The reef is only yards away, which is the second largest coral reef in the world. Swim with the turtles and an abundance of marine life, go diving and discover more, or use our complimentary kayaks. Local activities, include scuba diving, sailing, fishing, canopy tours, horseback riding, and much more. ... more less
- Reservation Options:
- TripAdvisor is proud to partner with Booking.com, Hotwire, Despegar.com, Expedia, Hotels.com, Priceline, Travelocity and Odigeo so you can book your Infinity Bay Spa and Beach Resort reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.
- Also Known As:
- Infinity Bay Spa And Beach Hotel West Bay
- Infinity Bay Hotel And Beach
- Infinity Bay Resort And Beach
- Infinity Bay Spa And Beach Resort Roatan, Bay Islands, Honduras


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Markets |
* Tops sheds 1.4 pct to trade below 1,000 * Exporters suffer after weak U.S. factory data * Real estate firms gain ahead of BOJ meeting this week By Dominic Lau TOKYO, April 2 Japan's Nikkei stock average dropped 1.8 percent to below the 12,000-mark for the first time in three weeks, with exporters like Canon taking a beating after weak U.S. factory data raised concerns about the recovery of the world's biggest economy. The Nikkei was down 213.87 points at 11,921.15 in midmorning trade, breaking below its 25-day moving average of 12,126.59 and extending the previous session's 2.1 percent decline. "People have plenty of profits to take. There are very few shorts out there in the market, so it ... creates a rather nasty fall," a senior dealer at a foreign bank said. The benchmark Nikkei rallied 19.3 percent in January-March, its best quarterly performance in nearly four years, after Prime Minister Shinzo Abe embarked on expansionary fiscal and monetary policies to revive the economy. The Bank of Japan is expected to announce further monetary easing steps after it concludes a two-day meeting on April 4. "You have got people, who have been away for Easter, come back to start selling. We are sellers here today but not enormously. People are taking profit, frightened by the yen," the senior dealer said. The yen rose to a one-month high of 92.96 to the dollar on Tuesday, rebounding from a 3-1/2-year low of 96.71 yen touched on March 12, after U.S. factory activity grew at the slowest pace in three months in March. The weak Institute for Supply Management data suggested the U.S. economy was losing some momentum at the end of the first quarter as the effects of a tighter fiscal policy kicked in. Exporters, which have rallied in recent months on the back of the yen's weakness, bore the brunt of the selling on Tuesday. Canon Inc, Toyota Motor Corp, Honda Motor Co, TDK Corp and semiconductor equipment maker Tokyo Electron lost between 1.6 and 3.8 percent. "The first-quarter performance was quite good, so investors want to take profit ... I am not worried about it too much," said Hisao Matsuura, an equity strategist at Nomura Securities. "I think the Nikkei can go down another 2 to 3 percent from here." He said he expected the Nikkei to test 13,000 by the end of June as the economy was likely to improve while the BOJ would keep its stimulus tap open. The broader Topix index shed 1.4 percent to 986.04, falling below the 1,000-mark for the first time in nearly four weeks. The Topix sank 3.3 percent on Monday, its biggest one-day percentage fall in two years. Engineering firm JGC Corp was a rare gainer, jumping 6 percent, after a consortium of France's Technip and JGC won a tender to build a liquefied natural gas plant on Russia's Yamal peninsula. Real estate and financial companies, which benefit from the government's drive to reflate the economy, also fared well. Mitsubishi UFJ Financial Group rose 0.2 percent and property firm Mitsui Fudosan added 3 percent.
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I'm trying to create a responsive site (resize the browser window to see the changes), but I'm unable to center these checkered divs.
The divs are dynamically created and appended to one of the four 'container' divs (#topLeft, #topRight, #bottomLeft and #bottomRight).
I have tried using margin-left:auto; and margin-right:auto on various elements, but that did not help.
Please help me horizontally center the #topLeft, #topRight, #bottomLeft and #bottomRight divs. I prefer a pure CSS solution, but if it is not do-able, I'm ok with a js tweak as well.