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Discover easy DIY beauty projects and get everything you need to try them at home at Darby Smart.
soap in pvc pipe
Tutorial on how I use PVC Pipe to make embedded cold process circular soaps. Two sizes PVC pipes used to expand on creating round column mold soaps. By Alaiyna B. Bath and Body
DIY Homemade Foot Lotion using inexpensive drugstore products.
How to Clean Your Face Naturally. (someone else said) I started using this (along with witch hazel) exclusively about 2 months ago and my skin looks the best it has ever looked. I haven't had any breakouts and my nose looks much cleaner - pores are clearer and smaller. I've gotten a ton of people that noticed the difference. Definitely recommend. (I have oily skin, so used the 3 castor oil : 1 evvo)
I'm crazy in love with this body serum and I will never use anything else because it has improved the quality of my skin and has helped it to look tan and very, very healthy. It does not make any sense to use chemicals when natural products can do better. This has everything my skin needs for tanning and moisturizing and leaves my legs glowing at night. It even helps with some eczema under my arms… I love it!
I have so much lipstick that I rarely wear.... DIY: Turn it into tinted lipbalm by melting Vaseline and Lipstick together then store in little pot. Genius!
Softest, Silkiest Legs!! I just tried this & cut the recipe in half bc it makes a lot!! & it worked amazingly & I was disgusted at the amount of dead skin I actually had! It's a must try - Brittney Brogdon
Free bath bomb recipes from Natures Garden. #bathbombs
The Homestead Survival | All Purposing Moisturizing Healing Salve Recipe |- Natural Remedies -
DIY Dry Shampoo
Are you looking for a fabulous #detox #bath? Here's a perfect recipe to leave you rejuvenated and refreshed! #DIY #frugal
Homemade Lip Gloss
Make your own "resort quality" liquid hand soap for pennies (One good thing by Jillie) I may not be into diy things yet but oh my gosh if this is from one bar of soap I could have a yr supply for the kitchen. I think I will give this a try next month.
Coconut-Lime Soap - 9 DIY Homemade Soap Recipes
Organic Rose and Shea Butter...Soap Tutorial ~ If you've ever wondered how to make your own #soap, you'll find answers in this interesting #tutorial from @latherandlotion
This complete guide explains step by step on how to make your very own homemade bath bombs in various shapes and colours. Make luscious looking bath bombs and mix and match colours and scents from floral to fresh to fruity! Includes how to make lemon, orange, fresh pine, lavender and rose bath bombs...
I might add some vanilla to make it smell like cupcakes. I'm all about cupcake smell!
MyFridgeFood - Easy Roast Chicken
After a long day or a hard workout, soothe sore muscles with an all-natural rub that gently warms and releases muscle tension. Made with ingredients you have in your pantry and a few essential oils, the sore-muscle salve also makes a nice massage lotion. And it smells a whole lot better than the kind you can buy at the store.
DIY Milk Bath- 1/2 c. oats (blended until finely ground), 2 c. powdered milk, 1/2 c. Epsom salts, 1/4 c. baking soda, 20 drops of essential oil for fragrance (optional). Mix ingredients together, store in resealable container.
Cute gift idea. Sweet Dreams With This DIY Sleep Salve: Tired of lying awake all night stressing over this or that?
DIY Gift Ideas ~ Homemade Lotion Bars: Keep your hands silky smooth with the help of DIY lotion bars that can go with you anywhere.
DIY Foot Soak Recipe + free printable label at TidyMom.net great handmade gift idea!
Homemade Sunscreen with Insect Repellant (Recipe)


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List all words ending with procercoids
Only the word procercoids was found, nothing longer.
Some random words: orle niblick ivermectin ihram kuchen wyandotte mbira
This is not a dictionary, it's a word game wordfinder.
- Help and FAQ - Examples - Home
Privacy and Cookies Policy - Share - © Copyright 2004-2016 Morewords.com - 82.101mS

subset: commoncrawl


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My name is Kathleen. I hold a BS in Mathematics and have seven years of experience tutoring all levels of math up to and including Calculus II. I have worked extensively with all levels of Math including Elementary, Middle, Algebra I, II, Geometry, Trigonometry, Pre-Calculus, Cal I,II, AP CAL AB and BC, FCAT 2.0, End of Course Exams (EOC), SAT, ACT, CPT, GED, and much more.
Hollywood, FLView Tutor
...I maintain currently maintain our company website using dreamweaver. I have also trained my co-workers on how to use several software applications, including Microsoft Office - (Word, Excel, Powerpoint, Access, and Outlook). My hobbies are reading, yoga, traveling and playing the guitar. I am easy-going, and easy to get along with.
Miami, FLView Tutor
...Lastly, I offer online tutoring via Skype... SUBJECTS TUTORING: -Anatomy and Physiology -Biochemistry -Biology -Chemistry, Intro -Chemistry, General -Chemistry, Organic -Genetics -Math -Medical Assistant -Medical School courses -Medical Terminology -Molecular and Cell Biology -Microbiology -...
Boca Raton, FLView Tutor
...My name's Tyler and I'm kind of a math nerd (surprise, surprise). Though I'd always helped to tutor both friends and family, I began professionally educating on mathematics during my final year of college. I began as a college lab instructor, tutor, and T.A. for a variety of college courses rang...
Deerfield Beach, FLView Tutor
Proficient in most areas of math such as: pre-algebra, algebra, algebra 2, geometry, precalculus, calculus, trigonometry, and data analysis/functions. Experienced for 11 years in tutoring for the FCAT, PSAT, SAT, ACT, TACHS, ISEE and GED examinations; specifically, my students have increased their ...
Homestead, FLView Tutor


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Apple job listings hint at future public transit integration for MapsA pair of job listings showed up on Apple's website this week looking for engineers qualified to implement new public transit-based features for the company's Maps app, which is now a part of iOS and OS X Mavericks.
Apple Maps as seen in OS X Mavericks.
The two Jobs at Apple postings, first spotted by MacRumors, seek a "Maps Public Transit Engineering Manager" and a "Maps C++ Software Engineer - Public Transit." Both listings were published on Monday.
Apple is expected to offer some sort of public transit information in a future build of Maps as it builds out the in-house mapping service. Competing navigation apps, including Google Maps, have had the feature for years.
As noted in one job description:
As a member of the Transit Routing team, you will work on one of the most anticipated features of Apple Maps. You will design and implement functionality that will be used by millions of users worldwide. Being part of a small team, you will have an influence on the future product.
Monday's job advertisements come two months after it was announced that Apple acquired Embark, an app and service company that offers public transit information for a number of metropolitan cities. The app was also highlighted by Apple as a stop gap solution for public transit directions after the company moved away from Google Maps.
In addition to the Embark buy, Apple earlier this year also purchased HopStop, an app that provides transit information for over 300 major cities, along with walking, car and bicycle routing.
Since Apple launched Maps with iOS 6, the service has come under fire for not being up to snuff when compared to the competition. Shortly after launching, users complained of erroneous information, UI bugs and other issues, prompting Apple CEO Tim Cook to issue a personal apology to customers, promising that the service would become more robust over time.
To that end, Apple has been constantly improving the app, the results of which can be seen in a more stable and feature-rich version that launched with iOS 7.
On Topic: General
- First look: Brooklyn celebrates the grand opening of its first Apple Store
- This week on AI: Q3 beats forecasts, 'Apple Car' leadership changes, augmented reality plans & more
- Apple urges Supreme Court to end long-running Samsung patent case
- Apple CEO Tim Cook, VP Lisa Jackson to host Clinton fundraising event
- Microsoft lays off 2,850 more people in continued retreat from phones


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Videos tagged "assmilk"
Tyler the Creator LIVE U Street Music Hall 3/18/201308:33
Tyler the Creator LIVE U Street Music Hall, Washington DC 3/18/2013 LIVE EXCLUSIVE CONCERT FOOTAGE!!!! Filmed by: Marcus Charles @OhhthatsMC Amazing show, Tyler did so many great songs! Like…+ More details
Tyler The Creator- "Assmilk" Music Video Feat. Earl Swatshirt04:06
Tyler The Creator raps about how much he hates kids like us.+ More details
Music video for "Earl." From The Album Earl. Download It At Oddfuture.com Directed by AG Rojas (www.whatupag.com)+ More details
Us doing hits, a popular thing to do on CBs, from the mod San Andreas Multiplayer.+ More details
What are Tags?
Tags are keywords that describe videos. For example, a video of your Hawaiian vacation might be tagged with "Hawaii," "beach," "surfing," and "sunburn."


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SIGN the petition to ban assault-style rifles in America
Assault rifles have been involved in countless mass shootings in America. They must be banned for sale.
Assault rifles have been involved in countless mass shootings in America. They must be banned for sale.
Philando Castile was murdered by police in front of his fiancé and 4 year old daughter
In wake of the largest mass shooting in American history, it's time to ban all assault rifles. Just. Ban. Them. NOW.
Media continues to under-report Bernie's support and push Hillary as the Democratic nominee. It's not fair or accurate.
Donald Trump is the nominee & his hate-filled speech will consume the event. AT&T needs to stand up for what is right.
In 2016, the Court will make major decisions that'll impact our environment, immigration, and even the right to vote.
Michigan Gov. Rick Snyder is hiding information about the decision to use contaminated water in Flint.
While all 6 officers who killed Freddie Gray are out of jail, many protesters face unjust criminal charges and high bail
Everyone deserves a voice in our democracy
One thing about almost all mass shooters: they wanted the fame. We need a media covenant to ignore them.
America's Military Has Kept Americans Free To Make This The Best Country In World History
We have 10 Reasons to Boycott Israel, read more
Facebook is a household name for millions of people around the world who use it to make friends, share pictures, and
To voice our support for those who spoke out against the abuses of the government against the poor and so-called
Native Women have lived under the longest and most violent Act of Cultural Genocide in the History of the World. Native
I wish to express my deepest sympathies to the families of those killed in the mass shooting in Orlando, Florida.
22 veterans die from suicide each day
Police cannot police themselves.
The Dominican Republic plans to purge Haitians, including those born there. Tell Carnival to reject ethnic cleansing.
McKinney Officer Eric Casebolt violently arrested, verbally assaulted and physically attacked Dajerria Becton.
ALEC says its a charity, but it's really a front for corporations to influence lawmakers. Tell the IRS to stop them.
The TPP's a secretive deal, negotiated behind closed doors, contains dangerous provisions that threaten Internet freedom
Tell Obama to appoint a new head of the DEA who will overhaul the DEA and reduce mass incarceration!
The CFPB has returned $5.3 billion to more than 15 million victims of predatory bank schemes and credit card scams.
A NYC Grand Jury refused to indict NYPD Officer Daniel Pantaleo for choking Eric Garner to death.
"Any human has the right to help his fellow man." Feeding The Homeless Is Not A Crime!
Obama's concerns about the humanitarian crisis and safety of US personnel can be solved without dropping bombs.
Racially-motivated police violence has no place in law enforcement.
Tell Target you expect more when it comes to keeping customers and employees safe from the risk of gun violence.
12-year old children can legally work in U.S. tobacco fields. They get nausea, headaches, & dizziness - take action now!
Tell US Fish and Wildlife Service it is the right decision to save wild elephants.
Orca Welfare & Safety Act would make it illegal to "hold in captivity, or use, orcas for performance or entertainment."
These laws endanger public safety and excuse the murder of innocent youth like Trayvon Martin and Jordan Davis.
Tell President Jacob Zuma and the Minister of Environmental Affairs to take action and protect rhinos from poaching
Chevron is using an obscure U.S. law to attack anyone who speaks out against its pollution of the Ecuadorian Amazon.
Taiji dolphin hunters have caught a real prize: A white albino dolphin calf who will die without his mother.
Black males in America are killed and incarcerated at an alarming rate more than any other race just for being black.
Innocent people are being put to death for crimes that they did not commit, this will eventually destroy our society
The Florida State House can no longer sit complacent while innocent people are victimized by 'Stand Your Ground'.
George Zimmerman is a dangerous, violent person and should NOT be licensed to carry a weapon.
Join the movement to pass a constitutional amendment that protects the right to vote for every citizen.
If you are burdened by predatory, exploitative private student loans, or federal student loans, you must sign this
Animal cruelty should be prohibited on Facebook in any shape or form.
If we want the system of law and order to respond ethically to rape and violence on women we will have to force the
Chino was shot and killed in Charlotte, NC on private property by a police officer D BRYAN on December 16, 2012. Ivy was
The federal minimum wage would be $10.76 if it had kept up with inflation over the past 40 years. Instead, it's $7.25.
Luego de ser despojados de sus tierras por hacendados y de que las instituciones judiciales del país no les fueran
The UCSD administration closed the Crafts Center facility on September 26, 2012 without prior notification.
---------------This video was produced in 2008, some statistics have since changed.--------------- The facts: -The
Founded in 1984 by choreographer Jawole Willa Jo Zollar, Urban Bush Women (UBW) seeks to bring the untold and under-told
For 6 years, we at The 50 Million Missing Campaign have been working hard to tell the world about the ongoing female


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|By Marketwired .
Article Rating:
|November 10, 2012 10:00 AM EST
DELHI, ONTARIO -- (Marketwire) -- 11/10/12 -- Seniors in Delhi will soon have new opportunities to get active and improve their health, thanks to support from the New Horizons for Seniors Program (NHSP). The Honourable Diane Finley, Minister of Human Resources and Skills Development, today announced funding for the Delhi Community Health Centre.
"The Harper Government recognizes the diversity of skills, knowledge and experience seniors contribute to our society and the economy," said Minister Finley. "Through the New Horizons for Seniors Program, the Delhi Community Health Centre will be able to continue its support for seniors in Delhi to stay active while contributing to the social and economic well-being of the community."
The Delhi Community Health Centre received $25,000 to create exercise programs and sports sessions for seniors.
"Seniors in Delhi built this community and they still have a lot to contribute, so we are proud to do our part to ensure that they have a high quality of life," added Minister Finley.
The Government invested more than $35.6 million in NHSP funding for almost 2 000 new community-based projects across Canada approved through the 2011-2012 call for proposals. For more information, please visit www.hrsdc.gc.ca/seniors.
This news release is available in alternative formats upon request.
New Horizons for Seniors Program
The New Horizons for Seniors Program (NHSP) is a federal grants and contributions program that supports projects led or inspired by seniors who make a difference in the lives of others and their communities. Through the NHSP, the Government of Canada encourages seniors to share their knowledge, skills and experiences for the benefit of others. Since it began, the Program has funded more than 10 400 projects in hundreds of communities across Canada.
The most recent call for proposals for community-based projects launched on May 8, 2012. It closed on June 29, 2012, in all provinces and territories except Quebec, which closed on September 14, 2012, and coincided with a provincial call for proposals.
Marian Ngo
Office of Minister Finley
Media Relations Office
Human Resources and Skills Development Canada
SYS-CON Events announced today that LeaseWeb USA, a cloud Infrastructure-as-a-Service (IaaS) provider, will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. LeaseWeb is one of the world's largest hosting brands. The company helps customers define, develop and deploy IT infrastructure tailored to their exact business needs, by combining various kinds cloud solutions.
Jul. 25, 2016 09:45 AM EDT Reads: 1,110
Whether your IoT service is connecting cars, homes, appliances, wearable, cameras or other devices, one question hangs in the balance – how do you actually make money from this service? The ability to turn your IoT service into profit requires the ability to create a monetization strategy that is flexible, scalable and working for you in real-time. It must be a transparent, smoothly implemented strategy that all stakeholders – from customers to the board – will be able to understand and comprehe...
Jul. 25, 2016 09:30 AM EDT Reads: 2,089
The cloud market growth today is largely in public clouds. While there is a lot of spend in IT departments in virtualization, these aren't yet translating into a true "cloud" experience within the enterprise. What is stopping the growth of the "private cloud" market? In his general session at 18th Cloud Expo, Nara Rajagopalan, CEO of Accelerite, explored the challenges in deploying, managing, and getting adoption for a private cloud within an enterprise. What are the key differences between wh...
Jul. 25, 2016 09:15 AM EDT Reads: 1,978
SYS-CON Events announced today that 910Telecom will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Housed in the classic Denver Gas & Electric Building, 910 15th St., 910Telecom is a carrier-neutral telecom hotel located in the heart of Denver. Adjacent to CenturyLink, AT&T, and Denver Main, 910Telecom offers connectivity to all major carriers, Internet service providers, Internet backbones and ...
Jul. 25, 2016 08:50 AM EDT Reads: 207
SYS-CON Events announced today that Venafi, the Immune System for the Internet™ and the leading provider of Next Generation Trust Protection, will exhibit at @DevOpsSummit at 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Venafi is the Immune System for the Internet™ that protects the foundation of all cybersecurity – cryptographic keys and digital certificates – so they can't be misused by bad guys in attacks...
Jul. 25, 2016 08:30 AM EDT Reads: 1,262
Large scale deployments present unique planning challenges, system commissioning hurdles between IT and OT and demand careful system hand-off orchestration. In his session at @ThingsExpo, Jeff Smith, Senior Director and a founding member of Incenergy, will discuss some of the key tactics to ensure delivery success based on his experience of the last two years deploying Industrial IoT systems across four continents.
Jul. 25, 2016 06:00 AM EDT Reads: 1,467
There will be new vendors providing applications, middleware, and connected devices to support the thriving IoT ecosystem. This essentially means that electronic device manufacturers will also be in the software business. Many will be new to building embedded software or robust software. This creates an increased importance on software quality, particularly within the Industrial Internet of Things where business-critical applications are becoming dependent on products controlled by software. Qua...
Jul. 25, 2016 05:45 AM EDT Reads: 1,356
SYS-CON Events has announced today that Roger Strukhoff has been named conference chair of Cloud Expo and @ThingsExpo 2016 Silicon Valley. The 19th Cloud Expo and 6th @ThingsExpo will take place on November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. "The Internet of Things brings trillions of dollars of opportunity to developers and enterprise IT, no matter how you measure it," stated Roger Strukhoff. "More importantly, it leverages the power of devices and the Interne...
Jul. 25, 2016 05:00 AM EDT Reads: 2,014
Machine Learning helps make complex systems more efficient. By applying advanced Machine Learning techniques such as Cognitive Fingerprinting, wind project operators can utilize these tools to learn from collected data, detect regular patterns, and optimize their own operations. In his session at 18th Cloud Expo, Stuart Gillen, Director of Business Development at SparkCognition, discussed how research has demonstrated the value of Machine Learning in delivering next generation analytics to imp...
Jul. 25, 2016 04:15 AM EDT Reads: 2,401
In addition to all the benefits, IoT is also bringing new kind of customer experience challenges - cars that unlock themselves, thermostats turning houses into saunas and baby video monitors broadcasting over the internet. This list can only increase because while IoT services should be intuitive and simple to use, the delivery ecosystem is a myriad of potential problems as IoT explodes complexity. So finding a performance issue is like finding the proverbial needle in the haystack.
Jul. 25, 2016 03:45 AM EDT Reads: 2,173
The Internet of Things will challenge the status quo of how IT and development organizations operate. Or will it? Certainly the fog layer of IoT requires special insights about data ontology, security and transactional integrity. But the developmental challenges are the same: People, Process and Platform. In his session at @ThingsExpo, Craig Sproule, CEO of Metavine, demonstrated how to move beyond today's coding paradigm and shared the must-have mindsets for removing complexity from the develo...
Jul. 25, 2016 01:45 AM EDT Reads: 1,237
SYS-CON Events announced today that MangoApps will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. MangoApps provides modern company intranets and team collaboration software, allowing workers to stay connected and productive from anywhere in the world and from any device.
Jul. 25, 2016 01:30 AM EDT Reads: 1,259
Basho Technologies has announced the latest release of Basho Riak TS, version 1.3. Riak TS is an enterprise-grade NoSQL database optimized for Internet of Things (IoT). The open source version enables developers to download the software for free and use it in production as well as make contributions to the code and develop applications around Riak TS. Enhancements to Riak TS make it quick, easy and cost-effective to spin up an instance to test new ideas and build IoT applications. In addition to...
Jul. 25, 2016 12:30 AM EDT Reads: 1,881
The 19th International Cloud Expo has announced that its Call for Papers is open. Cloud Expo, to be held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, brings together Cloud Computing, Big Data, Internet of Things, DevOps, Digital Transformation, Microservices and WebRTC to one location. With cloud computing driving a higher percentage of enterprise IT budgets every year, it becomes increasingly important to plant your flag in this fast-expanding business opportuni...
Jul. 25, 2016 12:15 AM EDT Reads: 2,495
"We've discovered that after shows 80% if leads that people get, 80% of the conversations end up on the show floor, meaning people forget about it, people forget who they talk to, people forget that there are actual business opportunities to be had here so we try to help out and keep the conversations going," explained Jeff Mesnik, Founder and President of ContentMX, in this SYS-CON.tv interview at 18th Cloud Expo, held June 7-9, 2016, at the Javits Center in New York City, NY.
Jul. 24, 2016 11:30 PM EDT Reads: 1,283
"delaPlex Software provides software outsourcing services. We have a hybrid model where we have onshore developers and project managers that we can place anywhere in the U.S. or in Europe," explained Manish Sachdeva, CEO at delaPlex Software, in this SYS-CON.tv interview at @ThingsExpo, held June 7-9, 2016, at the Javits Center in New York City, NY.
Jul. 24, 2016 11:00 PM EDT Reads: 1,514
From wearable activity trackers to fantasy e-sports, data and technology are transforming the way athletes train for the game and fans engage with their teams. In his session at @ThingsExpo, will present key data findings from leading sports organizations San Francisco 49ers, Orlando Magic NBA team. By utilizing data analytics these sports orgs have recognized new revenue streams, doubled its fan base and streamlined costs at its stadiums. John Paul is the CEO and Founder of VenueNext. Prior ...
Jul. 24, 2016 10:45 PM EDT Reads: 1,994
IoT is rapidly changing the way enterprises are using data to improve business decision-making. In order to derive business value, organizations must unlock insights from the data gathered and then act on these. In their session at @ThingsExpo, Eric Hoffman, Vice President at EastBanc Technologies, and Peter Shashkin, Head of Development Department at EastBanc Technologies, discussed how one organization leveraged IoT, cloud technology and data analysis to improve customer experiences and effi...
Jul. 24, 2016 10:00 PM EDT Reads: 1,968
The Internet of Things will challenge the status quo of how IT and development organizations operate. Or will it? Certainly the fog layer of IoT requires special insights about data ontology, security and transactional integrity. But the developmental challenges are the same: People, Process and Platform and how we integrate our thinking to solve complicated problems. In his session at 19th Cloud Expo, Craig Sproule, CEO of Metavine, will demonstrate how to move beyond today's coding paradigm ...
Jul. 24, 2016 09:45 PM EDT Reads: 2,131
Internet of @ThingsExpo, taking place November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, is co-located with the 19th International Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world and ThingsExpo Silicon Valley Call for Papers is now open.
Jul. 24, 2016 09:00 PM EDT Reads: 2,474


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Millennials will leave jobs that use technologies "not up to their standard" and they prefer to have "high-tech perks" than free food and ping pong, according to a global survey commissioned by Dell and Intel.
The Future Workforce Study questioned almost 4,000 employees in 10 countries working at various sized businesses. It found:]]>
- Almost half of global employees believe their current workplace is not smart enough, while 42 percent of millennial employees say they are willing to quit their job if office technologies are not up to their standard.
- More than 50 percent of employees expect to be working in a smart office in the next five years
- More than 80 percent of millennials say workplace tech would have an influence when deciding to take a job
- Half of all employees and three in five millennials believe technology will make face-to-face conversation obsolete in the near future
- More than 60 percent of millennials would rather receive high tech perks at work versus low tech perks like ping pong and free food
Read more here: http://www.dell.com/workforcestudy
Foremski's Take: Asking millennials what they want at work is a pointless exercise because as we all know, when you are young, job choices aren't abundant and in your first jobs you do what you are told to do with the tools available.
And as for millennials wanting better technology at work such as "augmented/virtual reality (AR/VR) and Internet of Things (IoT) than low-tech perks like ping pong, free food, etc," I detect the cynical response of the mischievous millennial mind.
The study does have a spattering of insights but it comes across as very self-serving for Dell and Intel to drum up sales for more tech products. And it is disingenuous to portray the opinions of a tiny number of millennials — a demographic with the least work experience — as experts on workplace technologies.
Millennials predicting technology will soon make obsolete face-to-face conversations in business, is an example of the lack of work experience in this survey group.
Marketers love to say that millennials are "born digital" but doesn't mean "born knowing all digital technologies." It just means they are a little faster at learning game player controls and user interfaces but workplace productivity is the sole responsibility of the employer.
Workplace technologies that deliver high productivity boosts will succeed —regardless of what employees want or not.
Is it OK to use the word "Guys" when addressing a mixed gender group of colleagues? Should women celebrate their feminine qualities or seek to avoid those stereotypes entirely at work?
These were some of the things discussed at a recent event, "The Gender Gap and How to Defeat It," organized by Thomson Reuters and hosted by Blurb, a self—publishing startup in San Francisco. It featured a panel of younger and older women working in the tech sector and primarily aimed at an audience of young women students preparing to enter the workplace.]]> The panelists represented a wide range of experiences of women in tech: Sarah Granger, author and consultant; Rachael O'Meara, sales executive at Google; Judith Basler, Director of Project Management at Blurb; Marine Leroux Thibault, Head of User Experience Design at Thomson Reuters; Donna Boyer, Director of Product at Airbnb; Nono Guimbi, Senior Software Engineer at Jawbone; Kelly Currier, Director Agile Delivery at Salesforce; Nancy Dickenson, consultant. More information on the speakers is here.
Here are some of my notes from the panel discussion:
- Women can manage teams of programmers without having to be coders themselves, said one of the panelists. But they do need to have some knowledge of the technology in order to give the right support to the engineers.
- Women managers tend to look at the psychology of the teams and how to ensure everyone works well together. Some try to "be human" and bring feminine values into the workplace. But this doesn't mean you have to bring home-baked cookies to the office or feel pressure to clean up after meetings, etc. Don't reinforce stereotypes. A woman in the audience said she did not want feminine qualities in the workplace and said she felt pressure to fulfill some of the social stereotypes.
- Just by being the only women in a room can change things for the better. Be authentic.
- Fear was discussed. There were stories of overcoming self-doubt and succeeding. Am I good enough? Do I measure up? Often, women will only apply for a job if they think they fulfill all the qualifications. Advice: Look at the job description as a wish list and still apply for the job (men will apply for jobs when they meet just 60% of the qualifications).
- Some panelists wished for more feedback and mentoring when they were younger because it would have helped their careers and avoid common mistakes.
- Recognition is important but women should ask for power in the workplace as they progress in their careers because that means they will be able to get things done, such as hire more women. Nothing will change unless you make the change happen and for that you need power.
- Ask for help. You don't have to know all the answers at work. Trust yourself.
- Not every tech company is the same. When looking for a job try to visit the company and see "what does it feel like?"
- Women who aren't software engineers can still work in the tech industry in jobs such as product managers, leading teams of specialists. They are good with people.
- A man asked, what are the expectations of men in the workplace? He was told to listen, to take part in the conversation over gender inequality. And to watch language at work. An audience member objected to the word "Guys" when used at work and referring to a mixed group.
- There has to be more women to choose from in the hiring pool because startups want to hire the best they can find regardless of gender.
- A frustration with slow progress. Dialog on workplace issues is not enough, there must be a concerted push for narrowing the gender gap otherwise change will be too slow.
It was an excellent panel discussion and I almost felt like a fly on the wall and listening to a frank discussion between the panelists and the audience on the issues they face as women in the workplace and how they can best support each other.
Is blockchain technology the second coming of the Internet? That seems to be the enthusiastic message from many new startups that I meet with and also from top business consultants such as Don Tapscott, who authored with his son Alex Tapscott, the recently published book, "Blockchain Revolution: How the technology behind Bitcoin is changing money, business, and the world."
Blockchain is a globally distributed ledger -- a platform for reliably clearing transactions without the need of a bank or other third-party. I get the concept behind blockchain, that everyone owns the same ledger and thus it can't be easily altered unless you can gain control of the majority of all the computing resources.]]>
But I don't yet get how this eliminates "middlemen" service fees after all, the startups in this sector are the new middlemen and have plans to make money on their services.
- how it can be scaled up to millions of transactions given the huge computational costs and the time taken to process a single transaction
- how can blockchain escape regulation by governments
- how can small blockchains provide the same levels of trust as the huge Bitcoin blockchain (which is larger than all of Google's server farms combined);
- and why will blockchain challenge giant corporations, as many have said, when giant corporations are the ones sponsoring the blockchain events and conferences, and seem to have the most to gain?
- where are the pain points? Surely, we have solved the problem of clearing transactions? Visa and Mastercard do it all day long and they manage to verify identity and guarantee security for a fairly low fee considering the 30% and more that Internet companies such as Apple and Google charge for handling payments for digital goods .
To find some answers, I turned to a recent event at the NASDAQ Innovation Center in downtown San Francisco that featured father and son Don and Alex Tapscott, followed by a panel discussion with John Wolpert, Global Blockchain Products Director at IBM; Haskell Garfinkel, Partner and FinTech co-lead at PricewaterhouseCoopers; and Ryan Smith, co-founder and CTO of Chain, a startup building blockchain infrastructure for financial institutions.
Above video, Alex Tapscott with his explanation of blockchain.
Below: The panel discussion.
Foremski's Take:I didn't get my questions answered but I did see a slide that appeared for a few brief moments at the end of Don Tapscott's presentation, about all the things that could stop blockchain. Some of my questions were represented as showstoppers on that slide.
Blockchain is certainly fascinating to watch, who will use it and the many new use cases being proposed.
The question is can blockchain overcome the many technical and societal challenges it faces, and emerge as a revolutionary technology that's nearly as important to the global economy as the Internet itself? Too early to call but not too early for the blockchain cheerleaders.]]>
Thomson Reuters and Blurb are hosting a special evening Tuesday June 28 in San Francisco, focused on the topic: Empowering women to work in technology.]]>
Technology is everywhere around us and we all use it, both men and women equally. Yet if men build all the technology, then women's needs won't be considered through technology. We need both men and women to build the technical future of our world. But "I'm not technical", you say? What happens when we go on maternity leave? How do women survive the male dominated tech world? This event will answer all those questions and inspire the most non-technical minded woman to consider a tech job.
There will be a screening of the documentary CODE: DEBUGGING THE GENDER GAP.
A panel discussion:
…with accomplished women leaders from Airbnb, Salesforce, Blurb, Jawbone and consultants. These amazing women will demystify the diversity of tech jobs and uncover various inspiring aspects of their career in technology: what inspired them to work in technology, obstacles they faced in their careers (like maternity), and their advice to young women.
Blurb Inc.
850 California Street @ Kearny
Suite 300
More info here.]]>
This year's Silicon Valley Forum Visionary Awards featured a tribute to the late Andy Grove, the legendary leader of Intel, who helped build the company into the world's most valuable semiconductor company.
Three additional people received a 2016 Visionary Award: Carl Bass, CEO Autodesk; Tom Wheeler, Chairman of the Federal Communications Commission and Jennifer Pahika, founder and Executive Director of Code for America.]]> The Silicon Valley Forum is one of the oldest professional associations in the SF Bay Area (it previously was known as SDForum)
Andy Grove died March 21, 2016 and his is the first posthumous award by the 33-year old organization. It was accepted by Craig Barrett, former CEO and Chairman of Intel. He recited a poem and praised Grove for his mentorship that included himself and many others, some who later became heads of large companies. Grove was an immigrant from Hungary and worked at Intel for more than three decades.
Jennifer Pahlka, founder and executive director of Code for America, was introduced by her husband Tim O'Reilly, founder of the publishing and events company O'Reilly Media, and a 2014 Visionary Award winner. Pahlka gave a passionate speech about government, communities, poverty and social justice.
Carl Bass, president and CEO of Autodesk spoke about the opportunties ahead. Tom Wheeler, the 31st Chairman of the Federal Communications Commission spoke about the importance of broadband infrastructure and net neutrality.]]>
US President George W. Bush is reported to have once said, "The problem with the French is that they have no word for 'entrepreneur.'"
The story about President Bush might not be true, but in many ways the story rings true because France certainly has developed an anti-entrepreneurial image abroad over the past few decades.
And maybe this is why I hear French spoken on the streets here all the time lately, far more than at any time prior, in my 30 years in San Francisco and Silicon Valley.]]> France's anti-entrepreneurial attitude is not easy to shake. A French startup CEO once told me his mother is embarrassed to tell her friends that he runs a startup, she'd be happier if he had a steady government job because business men and their monetary ambitions are distrusted in French society.
So it is not surprising that French entrepreneurs are here and are building new companies because it is a far easier place to do that both culturally and technically: this is the place for the best investment capital, best engineers and the best specialist executives for scaling startups.
I've heard estimates of more than 100,000 French people live and work in San Francisco and Silicon Valley.
I recently attended a gala dinner and awards event organized by the French American Business Association in San Francisco, and I was impressed by the large number of French founder startups that were being celebrated — far more than I remember seeing previously ( I helped judge the startup winners last year.)
Interestingly, at the event there were also awards given to the best new French founded wineries in California. It's great to see that California's expertise in tech and in wine attracts the French!
But it is not only the French that are here, pick almost any a country and you'll find it is represented in some way by local entrepreneurs because here it is quicker, easier and simpler to both start — and very importantly — to close down a business venture. It can take years of legal work to close a failed business in Germany, for example. Fail fast is key here because it means you can move on to the next idea.]]>
John Hennessy, one of Silicon Valley's most connected and successful businessmen, has ended his 16 years as President of Stanford University and nearly 40 years on the faculty.
He greatly expanded endowments and the university's engineering school, which has spawned companies such as Google and Yahoo.]]>
Marc Andreessen, the developer of one of the first web browsers and a top Silicon Valley investor has called Hennessy "Godfather of Silicon Valley." He sits on the boards of Google, Cisco Systems, and Atheros Communications.
Hennessy joined the faculty in 1977 just as Silicon Valley was starting. He co-founded MIPS Computer Systems in 1984, a maker of Reduced Instruction Set Computer (RISC) microprocessor chips and acquired for $333 million by Silicon Graphics in 1992.
As President of Stanford University he has raised massive amounts of money, $1.6 billion in 2015 alone, allowing for the expansion of Stanford's engineering school with a brand new quad, and many other buildings.
His engineering credentials and high profile in Silicon Valley's tech community have critics saying that Stanford is now seen as a tech-oriented school and it's humanities schools have suffered.
Under Hennessy Stanford University became the most exclusive and expensive private university in the US. This year less than 5% of nearly 44,000 student applicants were accepted, and its endowment grew to $21.5 billion.
The explosive demand for computer science (CS) Engineers helped fuel a big expansion of the computer science school at Stanford but it won't be enough to supply all the engineers needed by many industries.
In a recent interview published in "The Communications of the ACM" Hennessy warned,
We're going to struggle to meet the [CS] demand. All institutions are facing this because CS graduates have lots of good opportunities, both within the academy as well as outside it. We're also going to see other fields begin to change, but change takes a long time. Universities change at a very slow pace getting new faculty.
However, I think we can already see the rise of quantitative empirical analytical approaches, for example take a discipline like political science. The action is in doing big data analysis of elections and surveys. It requires a different kind of expertise and background.
…We're going to see a rise of the influence of big data in the social sciences, and they're going to become more quantitative in how we formulate policy.
Please see:
Hennessy's term as President comes to close | Stanford Daily
An Interview with Stanford University President John Hennessy | March 2016 | Communications of the ACM
iCharts founder and CEO Seymour Duncker
The future calls for enterprise apps becoming aggregators of trusted IT micro-services from many sources — does that mean they can become effective data integration platforms? A low-cost path to Big Data's promises of profitable business insights?]]>
Today's announcement by iCharts that its visual intelligence software is now available inside Netsuite Enterprise is an example of how an application can integrate data from many sources both internal and external inside the application. Where better to have insights into the business than inside accounting software?
From the news release:
Powered by the Google Cloud Platform, the new iCharts offering will empower NetSuite customers that rely on external business systems and data sources to visualize their entire business within NetSuite, thereby giving them a true 360-degree view of their business.
In particular, NetSuite customers can visually blend data from sources such as:
-Other business systems (e.g., CRM, Marketing, web analytics)
- 3rd-party market data such as Nielsen and Dun & Bradstreet
- Historical or legacy data if you they are migrating from a legacy ERP system to NetSuite
Winning in Big Data will be all about: which screen are you on? Netsuite users live inside Netsuite screens and that's true for other key users and their apps. Reaching users inside the applications where they work all day also means they have the information they need at precisely the place where they can do something about it.
Here's an iChart user:
"Our live production data resides outside of NetSuite, yet it is important for us to see this data alongside the other key indicators we manage inside of NetSuite," said Brian Krosschell, Finance Director, fairlife, makers of value-added dairy products.
"iCharts has given us the platform to bring this data to life, allowing us to seamlessly integrate external data live for our users directly inside our NetSuite dashboard."
More info here: http://icharts.net


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New Sources, Methods, and Field StrategiesContemporary Chinese Politics: Sources, Methods, and Field Strategies considers how new and diverse sources and methods are changing the study of Chinese politics. Contributors spanning three generations in China studies place their distinct qualitative and quantitative methodological approaches in the framework of the discipline and point to challenges or opportunities (or both) of adapting new
Civil Dispute Resolution in Contemporary ChinaThis volume analyzes whether China's thirty years of legal reform have taken root in Chinese society by examining how ordinary citizens are using the legal system in contemporary China. It is an interdisciplinary look at law in action and at legal institutions from the bottom up, that is, beginning with those at the ground level that are using and working in the legal system. It explores the
The New Institutionalism in Organizational AnalysisLong a fruitful area of scrutiny for students of organizations, the study of institutions is undergoing a renaissance in contemporary social science. This volume offers, for the first time, both often-cited foundation works and the latest writings of scholars associated with the "institutional" approach to organization analysis. In their introduction, the editors discuss points of convergence and
When the People Speak:Deliberative Democracy and Public Consultation
Deliberative Democracy and Public ConsultationAll over the world democratic reforms have brought power to the people-but under conditions where the people have little opportunity to think about the power that they exercise. Do we want a democracy inspired by Madison or by Madison Avenue? A democracy animated by deliberation or by manipulation? This book examines each of the principal democratic theories and makes the case for a democracy in
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$27.99Global governance is here--but not where most people think. This book presents the far-reaching argument that not only should we have a new world order but that we already do. Anne-Marie Slaughter asks us to completely rethink how we view the political world. It's not a collection of nation states that communicate through presidents, prime ministers, foreign ministers, and the United Nations. Nor
The Dialectic of the Global and the LocalComparative Education: The Dialectic of the Global and the Local, Third Edition brings together many of the outstanding scholars in the field of comparative and international education to provide new perspectives on the dynamic interplay of global, national, and local forces as they shape the functioning and outcomes of education systems in specific contexts. Various chapters in the book call for
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Evaluating the Practice and Impact of Deliberative Civic EngagementAlthough the field of deliberative civic engagement is growing rapidly around the world, our knowledge and understanding of its practice and impacts remain highly fragmented. Democracy in Motion represents the first comprehensive attempt to assess the practice and impact of deliberative civic engagement. Organized in a series of chapters that address the big questions of deliberative civic
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Governance and Public ManagementA multidisciplinary analysis of the role of values and virtue in public administration, this book calls for a rediscovery of virtue. It explores ways of enabling the public sector to balance the values that are presently dominant with classic values such as accountability, representation, equality, neutrality, transparency and the public interest.


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Expats In , Nicaragua
If you are looking to connect with expats in Nicaragua, then this page brings together all the latest expat blogs Nicaragua written, any interviews, articles and news items we have here at ExpatsBlog.com.
Latest Blogs by Expats Living in Nicaragua » more expat blogs
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See where my heart leads me
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Hi! I'm Ernesto, and currently living in Sunny Madrid, Spain for almost 2 years. My stay is indefinite, and so, I'll just continue to enjoy all the tapas, tintas, the paellas & bocadillos, and all the attractions this city and beyond offer.
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MASTER OF CEREMONIES Vic Fernandes told Carols By Candlelight fans not to expect any rain, but the rain came. He was so busy spreading cheer that he forgot to tell them to light their candles, but they did anyway. None of these things dampened spirits when the annual event was held last Sunday at Ilaro Court. People had begun trekking into the forecourt for the event, in its 17th year under the Rotary Club of Barbados, more than an hour before the scheduled start, to secure spots for collapsible chairs and spread blankets. Some flowed down the hill, toting their duffel bags and picnic baskets.


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center for transportation safety jobs
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Transportation technical certification or field experience in DOT, IATA, IMDG, and TDG preferred. 3E Company is leading the future in the supply chain and...
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Transport America - Greenwood, SC
Satisfactory safety and employment history. 13 Support Centers across the county. Safety with a CSA score to back it....
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The unique evolution of the programmed cell death 4 protein in plants
Evolutionary developmental biology and morphology
The programmed cell death 4 (PDCD4) protein is induced in animals during apoptosis and functions to inhibit translation and tumor promoter-induced neoplastic transformation. PDCD4 is composed of two MA3 domains that share similarity with the single MA3 domain present in the eukaryotic translation initiation factor (eIF) 4G, which serves as a scaffold protein to assemble several initiation factors needed for the recruitment of the 40S ribosomal subunit to an mRNA. Although eIF4A is an ATP-dependent RNA helicase that binds the MA3 domain of eIF4G to promote translation initiation, binding of eIF4A to the MA3 domains of PDCD4 inhibits protein synthesis. Genes encoding PDCD4 are present in many lower eukaryotes and in plants, but PDCD4 in higher plants is unique in that it contains four MA3 domains and has been implicated in ethylene signaling and abiotic stress responses. Here, we examine the evolution of PDCD4 in plants.
In older algal lineages, PDCD4 contains two MA3 domains similar to the homolog in animals. By the appearance of early land plants, however, PDCD4 is composed of four MA3 domains which likely is the result of a duplication of the two MA3 domain form of the protein. Evidence from fresh water algae, from which land plants evolved, suggests that the duplication event occurred prior to the colonization of land. PDCD4 in more recently evolved chlorophytes also contains four MA3 domains but this may have resulted from an independent duplication event. Expansion and divergence of the PDCD4 gene family occurred during land plant evolution with the appearance of a distinct gene member following the evolution of basal angiosperms.
The appearance of a unique form of PDCD4 in plants correlates with the appearance of components of the ethylene signaling pathway, suggesting that it may represent the adaptation of an existing protein involved in programmed cell death to one that functions in abiotic stress responses through hormone signaling.
Following transcription and processing of an mRNA, the ribosome is responsible for performing protein synthesis. Although the bacterial 30 S ribosomal subunit can identify the initiation codon through base-pairing between the 3′-end of its16 S ribosomal RNA subunit and the Shine-Dalgarno sequence upstream of the initiation codon, the 40 S ribosomal subunit of the eukaryotic 80 S ribosome requires several translation initiation factors (eIFs) for its binding to an mRNA and to identify the initiation codon
eIF4A binds to two regions of eIF4G that fold into HEAT (Huntington, Elongation Factor 3, PR65/A, TOR) domains, characterized by the presence of antiparallel α-helical hairpins known as HEAT repeats
In addition to eIF4G, other proteins containing an MA3 domain have been described. The programmed cell death 4 (PDCD4) protein is characterized by the presence of two tandem MA3 domains that fold into a subtype of HEAT domains. The N- and C-terminal MA3 domains of human PDCD4 contain four and three helical hairpins, respectively, while eIF4G-MA3 contains five helical hairpins
PDCD4 homologs are present in lower eukaryotes and plants although no PDCD4 homolog has been reported in yeast. PDCD4 proteins in higher plants are unique in that they contain four tandem MA3 domains. Higher plants also appear to lack a two MA3 domain PDCD4 homolog. One such four MA3 domain PDCD4 protein (ECIP1) was reported to bind
MA3-domains are present in multiple proteins in plants
eIF4G contains a single MA3 domain which in plants, is present at the C-terminus as plant eIF4G lacks the HEAT-3/Mnk-binding domain found in animal eIF4G (Figure
Figure 1
Domain organization of MA3 domain-containing proteins in
Domain organization of MA3 domain-containing proteins in
In addition to eIF4G, animals express PDCD4, which contains two tandem MA3 domains
Additional file 1
Sequence comparison of the MA3 domains in
Click here for file
Figure 2
Phylogenetic analysis of the MA3 domains of
Phylogenetic analysis of the MA3 domains of
The four MA3 domain PDCD4 protein is unique to plants
PDCD4 homologs are present throughout angiosperm species and the proteins exhibit considerable conservation both in domain organization and primary sequence (Figure
Figure 3
Sequence alignment of plant PDCD4 homologs
Sequence alignment of plant PDCD4 homologs. Alignment of PDCD4 amino acid sequence is shown with amino acid identity relative to
The four MA3 domain PDCD4 protein arose during algal evolution
PDCD4 in animals and many lower eukaryotes, including several algal species, contains two MA3 domains while the PDCD4 homolog in other algal species and land plants contains four MA3 domains. This raises the question of when duplication of the two MA3 domain protein into a four MA3 domain protein may have occurred. Examination of the available genome sequences for algae and algal relatives revealed the presence of four MA3 domain PDCD4 homologs in more recently evolved green algae such as
Additional file 2
Domain organization of PDCD4 homologs in algae and algal relatives. The domain organization of PDCD4 homologs is shown for green algae and algal relatives with the MA3 domains indicated in blue. PDCD4 proteins for green marine algae (
Click here for file
Phylogenetic analysis of MA3 domains 1–2 and MA3 domains 3–4 of
Additional file 3
Sequence analysis of the MA3 domains of PDCD4 homologs in algae and algal relatives suggests domain duplication in at least some chlorophytes. A phylogenetic tree was generated using the sequences comprising MA3 domains 1–2 and MA3 domains 3–4 of the four MA3 domain PDCD4 homologs of chlorophytes
Click here for file
If the four MA3 domain PDCD4 homolog of
Figure 4
Intron positions in the
Intron positions in the
As land plants did not evolve from Chlamydomonadales but rather from charophytes (i.e., fresh water algae), the appearance of a four MA3 domain PDCD4 homolog in
Thus, examination of charophyte PDCD4 homologs might more precisely determine when the four MA3 domain form of the protein appeared during the evolution of land plants. Although little genome sequence information is available for charophytes, a search of the EST database identified a partial PDCD4 cDNA from
Figure 5
Sequence alignment of four MA3 domain PDCD4 homologs in algae and land plants
Sequence alignment of four MA3 domain PDCD4 homologs in algae and land plants. Alignment of PDCD4 amino acid sequence is shown with amino acid identity relative to
The PDCD4 gene family underwent expansion during land plant evolution
The PDCD4 homolog in
Gene divergence often follows gene duplication. To determine how the plant PDCD4 gene family members may have diverged during the evolution of land plants, phylogenetic analysis of the gene family was performed. Because of the poor sequence conservation of the N-terminus, only the region containing the four MA3 domains was used for the analysis. Although the
The single PDCD4 gene family members of
Figure 6
Phylogeny of PDCD4 homologs in higher and lower plants
Phylogeny of PDCD4 homologs in higher and lower plants. Phylogenetic analysis of the aligned sequence comprising MA3 domains 1 to 4 for the four MA3 domain PDCD4 proteins of the plant species indicated. The phylogenetic tree was constructed using the maximum-likelihood method. Numbers on each branch denote percentages of bootstrap support. The MAT5/6/7 subgroup of monocots and dicots is shaded yellow, the MAT8 subgroup is shaded green, the PDCD4 homologs in gymnosperms is shaded purple, while those of early land plants and
These data suggest that the two genes produced from the duplication of the original PDCD4 gene during early higher plant evolution might have been the progenitor genes for MAT8 and the MAT5/6/7 subgroups and the latter subgroup underwent expansion in some species. However, the considerable similarity of the two PDCD4 homologs in
The PDCD4 homologs in
Figure 7
Comparison of basal angiosperm and gymnosperm PDCD4 homologs with other land plants
Comparison of basal angiosperm and gymnosperm PDCD4 homologs with other land plants. Alignment of PDCD4 amino acid sequence is shown with amino acid identity relative to
To examine if the deletions in each MA3 domain affect the same region, the individual MA3 domains from
Figure 8
Comparison of the MA3 domains of
Comparison of the MA3 domains of
As these deletions are not present in the early land plants
Discussion and conclusions
These results suggest that the domain organization of PDCD4 homologs in most lower plants, i.e., algae and algal relatives, is similar to those in animals in that it contains two MA3 domains but it underwent duplication to a four MA3 domain form in some recently evolved chlorophytes such as
The PDCD4 homologs of the angiosperm species examined have diverged into MAT8-like and MAT5/6/7-like subgroups. No MAT8 homolog was identified in gymnosperm or basal angiosperm species, but appeared at or prior to the evolution of species within the Piperales such as
Interestingly, the PDCD4 homologs in early evolved gymnosperm and angiosperm species possess two deletions within each MA3 domain relative to early land plants. The observation that these deletions are present in both early evolved gymnosperm and angiosperm species supports the notion that they occurred prior to the appearance of the distinct gymnosperm and angiosperm lineages. However, the fact that these deletions are not observed in angiosperm species since (and including) the evolution of
These observations collectively raise the question of what advantage does a four MA3 domain PDCD4 protein confer to recently evolved algal species and land plants and what advantage does expansion of the PDCD4 gene family confer to plants as they transitioned from an aquatic to a terrestrial environment? Loss of expression of just one of the four PDCD4 proteins in
Sequence alignment and phylogenetic analysis
MA3-containing sequences obtained from
Additional file 4
Aligned sequences used for the phylogenetic analysis of Figure
Click here for file
Additional file 5
Aligned sequences used for the phylogenetic analysis of Additional file
Click here for file
Additional file 6
Aligned sequences used for the phylogenetic analysis of Figure
Click here for file
ECIP1: EIN2 C-terminal interacting protein 1; eIF: Translation initiation factor; HEAT: Huntington, Elongation Factor 3, PR65/A, TOR; MAT: MA three; PABP: Poly(A) binding protein; PDCD4: Programmed cell death 4.
Competing interest
The authors declared that they have no competing interest.
Authors' contributions
DG conceived of the study and directed its design and coordination. DG, RL, and SC contributed to the sequence alignment, phylogenetic analysis, and preparation of the manuscript. All authors read and approved the final manuscript.
The authors thank D. Soltis, J. Leebens-Mack, Tao Chen, T. Kutchan for sequences from the Onekp project. This work was funded by a grant from the National Science Foundation (DBI-0820047) and the University of California Agricultural Experiment Station.
Starting the protein synthesis machine: eukaryotic translation initiation
The molecular mechanics of eukaryotic translation
The mechanism of translation initiation in eukaryotes
Wheat germ translation initiation factor eIF4B affects eIF4A and eIFiso4F helicase activity by increasing the ATP binding affinity of eIF4A
Modulation of the helicase activity of eIF4A by eIF4B, eIF4H, and eIF4F
Wheat eukaryotic initiation factor 4B organizes assembly of RNA and eIFiso4G, eIF4A, and poly(A)-binding protein
Protein-protein interactions required during translation
Wheat germ poly(A) binding protein enhances the binding affinity of eukaryotic initiation factor 4F and (iso)4F for cap analogues
Eukaryotic initiation factor 4B and the poly(A)-binding protein bind eIF4G competitively
A common function for mRNA 5′ and 3′ ends in translation initiation in yeast
Circularization of mRNA by eukaryotic translation initiation factors
A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery
Two structurally atypical HEAT domains in the C-terminal portion of human eIF4G support binding to eIF4A and Mnk1
Eukaryotic translation initiation factor 4E (eIF4E) binding site and the middle one-third of eIF4GI constitute the core domain for cap-dependent translation, and the C-terminal one-third functions as a modulatory region
Interaction between the NH2-terminal domain of eIF4A and the central domain of eIF4G modulates RNA-stimulated ATPase activity
Characterization of the two eIF4A-binding sites on human eIF4G-1
Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E
The plant translational apparatus
Competitive and noncompetitive binding of eIF4B, eIF4A, and the poly(A) binding protein to wheat translation initiation factor eIFiso4G
PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains
Isolation of a novel mouse gene MA-3 that is induced upon programmed cell death
Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation
A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-ĸB or ornithine decarboxylase transactivation
Downregulation of tumor suppressor Pdcd4 promotes invasion and activates both beta-catenin/Tcf and AP-1-dependent transcription in colon carcinoma cells
DUG is a novel homologue of translation initiation factor 4G that binds eIF4A
The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation
A novel function of the MA-3 domains in transformation and translation suppressor Pdcd4 is essential for its binding to eukaryotic translation initiation factor 4A
Structural basis for translational inhibition by the tumour suppressor Pdcd4
Structural basis for inhibition of translation by the tumor suppressor Pdcd4
Structure of the C-terminal MA-3 domain of the tumour suppressor protein Pdcd4 and characterization of its interaction with eIF4A
EIN2 regulates salt stress response and interacts with a MA3 domain-containing protein ECIP1 in
eIF4G functionally differs from eIFiso4G in promoting internal initiation, cap-independent translation, and translation of structured mRNAs
Deletion of the eIFiso4G subunit of the Arabidopsis eIFiso4F translation initiation complex impairs health and viability
Identification of important regions for ethylene binding and signaling in the transmembrane domain of the ETR1 ethylene receptor of Arabidopsis
Uncovering the evolutionary origin of plant molecular processes: comparison of
Ethylene perception and signaling: an evolutionary perspective
The construction and use of log-odds substitution scores multiple sequence alignment
Phytozome: a comparative platform for green plant genomics
The Norway spruce genome sequence and conifer genome evolution
ExPASy: the proteomics server for in-depth protein knowledge and analysis
Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0
LG: an improved, general amino-acid replacement matrix


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BREAKING >>> Shut the FUCK UP About Voting - WHAT'S WRONG WITH YOU ALL???
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Voters whine and Whiners vote
Grow up and take charge. The Republic is here to preserve and protect your lawful right to live free and live independently from the tyranny of popular public opinion regardless of any vote.
The U.S. Corporation, on the on the other hand is chocked full of benefits and privileges and will give you all kinds of shit in exchange for your submission/vote and your labor under one of their "jobs" most all of them in place to strengthen and enhance their control.
It sees you wanting. It smells you needing. It lures you in and reaches around you to shut the door to your Republic.
And then it screws you and tells you not to worry: Just obey and everything will be okay.
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WIKILEAKS JULIAN ASSANGE Says He Has NEW Emails That Should Indict Hillary…And Why He's A Trump Fan
Undercover Video: Hillary Clinton Delegate Explains Her Deceptive Propaganda to Ban Guns
Is State Dept. Is Protecting Hillary Rotten Clinton's Presidential Bid?
Robots, drones fill police ranks
Companies around globe packing earth orbit with satellites to meet communications demands
Rise of black nationalist groups
Report: Mr. Robot's one-time only VR experience will return next week
'Kill More Cops' Graffiti Mural Appears on Freeway
DNC erects four-mile eight-foot tall fence around Philly convention site
Should the Postal Service Handle Your Loans as Well as Your Mail? Elizabeth Warren Thinks So.
HERE IT IS=> Detailed List of Findings in Wikileaks DNC Document Dump
BREAKING: That Was Fast! Hillary Immediately Brings Disgraced DNC Chair Onto Her Campaign! Do you think that Hillary has something to hide?
According to Soros, there's about to be an all-out class war riots, police state and civil war for America
Torrential Downpour To Kick Off Hillary's #DNC Election Steal
Montel Williams Goes Off On Bill O'Reilly For Flipping The Script On Their Interview
Dennis Miller, "Any Vote for Anyone That is Not Trump Is a Vote for Hillary"
Protester shouting 'DNC Leak!' ejected from Hillary Rally
CNN ASKS BLACK TRUMP SUPPORTER The Wrong Question…They Get Slammed!
If Obama brings armed UN troops into American cities, that might be the next shot heard round the world.
LOL Of The Day - "Hillary for Prison" banner plane spotted over Philadelphia
Congress approves Monsanto Dark Act 2.0, destroying consumers' chances of having on-package labels
Don't let the globalists start a race war!
If you grow food in cinder blocks, you may be poisoning yourself with heavy metals
Doctor at psychiatric hospital accused of experimenting on children with 'truth serum' drug used on soldiers during WWII
Ohio moves towards mandatory vaccines, proposing to eliminate philosophical exemptions entirely
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...I have a B.A. in Mathematics, with a teaching minor in Physics. I am also an online student at Ashford University, working toward a Master's degree in Special Education.Algebra is my specialty. I can explain the concepts in many different ways, and all of the students I have taught have done very well after they've been tutored by me.
Tacoma, WAView Tutor
Beginner or Advanced instruction in AutoCAD, Revit, Inventor and Revit MEP. Adjunct Faculty at local Community College and am a small business owner. I have worked in the Commercial Building Trades 30+ years and enjoy the interaction between fellow CADD (Computer Assisted Drafting & Design)users and the camaraderie that develops.
Port Orchard, WAView Tutor
My BA is in Photo-Illustration. I taught Portrait/Commercial Photography at the community college level, have worked as a commercial photographer and videographer/producer. I am skilled in AfterEffects and Avid Media Composer.
Tacoma, WAView Tutor
...We can work together to set up the best plan for success. As long as there is effort, we can work well together.I am currently teaching Algebra 2 at the high school level. I tutored for multiple years.
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...I am patient and take the time to provide an overall understanding of the subject. We are a very math oriented family - my two sons scored 740 and 800 on the SAT. I am a Native German Speaker and have used my language skills for over 15 years to evaluate and hire German translators and editors as a project manager for international companies.
Kirkland, WAView Tutor


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- Woman sleeping in car accused of attacking Cape officer (7/26/16)13
- Seeking new history: Centurion Development buys former Woolworth building at 1 N. Main St. (7/28/16)5
- Prosecutor says shooting by state trooper was justified (7/24/16)15
- Cape resident gets seven years in prison for shooting at man (7/26/16)1
- Former Scott City mayor refutes claims made about loss of curbside recycling pickup (7/26/16)
- Burglary of trailer leaves its residents homeless (7/27/16)4
- Golden Corral coming to Cape; may hire 100 workers (7/21/16)10
- Police: Child's video revealed stepfather's abuse of sibling (7/28/16)3
- Foot plots provide habitats and nutrition to attract wildlife, grow populations (7/18/16)
- City may spend extra park tax money on Cape Splash, skate park, other projects (7/25/16)10
Central softball team seizes shot at district title
Central earned the chance to repeat as district champs with a 4-2 win over Jackson
The top-seeded Central Tigers were able to get on the board early in their district semifinal matchup against fifth-seeded Jackson when Madison Daum hit a leadoff triple and eventually was driven in by Kadie Orenstein on a fielder's choice in the bottom of the first inning.
Central led until the Indians tied it in the top of the fourth, but the difference came down to one seized and one missed opportunity in the fifth and sixth innings.
It was the Tigers who made the most of their chance as they defeated Jackson 4-2 in a Class 4 District 1 softball semifinal Thursday at Central.
"Well, we knew coming in Jackson was hot," Central coach Amy Blattel said. "They were playing very, very well and they're a much better ball club than their record shows and we have a lot of respect for them and their coaching staff. So we knew it was going to be a battle and we knew we were going to have to play hard the whole game."
Central's lead against the Indians never exceeded three runs, but the Tigers had other opportunities to pull away.
"Honestly, I thought we came in and we played the best team in this district right now," Jackson coach Ashley Litzelfelner said. "We always bring it whenever we come play Cape. It's always a battle. We gave all we could, and they pushed us to our limits. They outhit us today, and that's what won the ballgame."
Central catcher Sarah Kitchen made crucial plays offensively and defensively to help the Tigers secure the victory. With two outs and two runners on in the fifth inning Kitchen doubled to center field to give the Tigers a 4-1 lead.
"I saw runners on and knew I had to relax up at the plate and drive the ball," Kitchen said.
Kitchen threw a Jackson runner out at second on an attempted steal to record the first out of the sixth inning and clear the bases.
Jackson's Mallorie Maintz singled later in the inning before two consecutive errors by Central allowed her to score to cut the lead to 4-2.
Central pitcher Kadie Orenstein's lone walk of the game loaded the bases, but she struck out a batter to end the threat.
"The only thing that was going through my head was, 'Let's do this,' Litzelfelner said. "Hoping and praying that we could get something to push our girls forward, and we got the bases loaded and just couldn't produce."
Central will try to defend its district title when it faces Hillsboro in the district championship at 11 a.m. Saturday at Central.
The Tigers beat Hillsboro 8-6 earlier in the season.
"It's going to be tough," Blattel said. "When you get down to it, those games prior to a district championship really don't mean a whole lot because both teams are different. We saw them very early in the year. ... It's going to be a battle. We're going to have to play ball the way we're capable of playing ball."
Central improved to 16-5, while Jackson's season ended at 10-15.
"This was a good win for us today, but we've got to put this one behind us and come out and do work tomorrow in practice," Orenstein said. "We know we've got to take care of business on Saturday. We still have a lot of work to do."
WP -- Kadie Orenstein. LP -- Sophie Wunderlich. Leading hitters -- Central: Sarah Kitchen 3-3, 2 2B, 2 RBI; Maddie Daum 3-3, 3B; Sydney Tollison 2-3, 2B. Jackson: Erica Gray 1-3, 2B, 1 RBI; Taylor Bauknecht 2-4. Records -- Central 16-5, Jackson 10-15.


text: Win 2,000 Tickets to the Stone Age of ComputersMicah Fitzerman-Blue – Bureau Of Trade8/29/12 6:20pmFiled to: Past PerfectBureau of tradeInternational Business Machines21EditInvite manuallyPromoteDismissUndismissHideShare to KinjaToggle Conversation toolsGo to permalink You saved your vacuum tubes and you still speak fluent FORTRAN. All you need now is this collection of two thousand 1960s-era punchcards from the computer sciences whizzes over at International Business Machines. There's gotta be enough data here to start up a game of PONG.For 21st-century collectors with a taste for retro tech, there is no better stationery, memo pad, letterhead, thank-you note, wedding invitation (check with the bride), or business card material than these historic relics. Intending to put them to multiple use? Fear not: They come in three colors.Reply21 repliesLeave a reply


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Men's Saxx 'Vibe - Topograph' Stretch Boxer Briefs,
A sleek, stretch-fit blend forms sharp briefs featuring an ergonomic comfort pouch and a signature nine-panel build. Patented mesh panels provide ultimate ease by reducing friction and offering reliable support. Color(s): malibu topo, sulphur topo. Brand: SAXX. Style Name: Saxx 'Vibe - Topograph' Stretch Boxer Briefs. Style Number: 1025199_9. Learn More


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March 10, 2013
Chinese,Indian,and Korean,my favorite dish is chicken vindaloo.
Yes I understand and agree.
Hello my name is Leroy McCoy I am a 48 year old foodie and I'm addicted to good healthy vibrant cuisines of all kinds. I'm a single parent of a teenaged son and I love experiment with food learning as I go along.
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so playful :)
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I really like this. :)
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We are greated by a friendly staff. Jason our server came over to us ro take our order. He is great ! Great food . All homemade. Delicious. You will not be disappointed. A must try. You will be back.
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Pope prays at Western Wall in Jerusalem
JERUSALEM - Pope Francis on Monday prayed at the Western Wall in Jerusalem, the holiest site for Jewish prayers, after visiting the nearby Al-Aqsa mosque.
Placing his right hand on the ancient stones, he bowed his head for a few minutes before placing a note in the wall, then sharing an emotional embrace with two close Jewish and Muslim friends travelling with him.
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Photo Special10 Best Celeb Quotes This Week
Donald Trump's pizza party bashing by Jon Stewart, plus more from Justin Timberlake, Blake Lively and other stars
Credit: Courtesy Leann Rimes
Updated: Friday Jun 03, 2011 | 06:00 AM EDT By: Christie LaRusso
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text: Sterling Silver Belt Bangle by Otis Jaxon Silver Jewellery £99.75$178.58€120.32$133.88 In stock £18.50$33.12€22.31$24.83 delivery to United States Receive this item 5-10 working days from dispatch International delivery available jewellery optionjewellery option (required)Sterling Silver bangleDuo banglejewellery option (required)Sterling Silver bangleDuo banglejewellery option (required)Sterling Silver bangleDuo banglejewellery option (required)Sterling Silver bangleDuo bangle quantity by Otis Jaxon Silver Jewellery Location: London, GB read seller's profile see seller's complete range more items from this seller 20% OFF Gold And Sterling Silver Screw Bangle by Otis Jaxon Silver Jewellery £99.75$178.58€120.32$133.88 £79.80$142.86€96.26$107.10 Contemporary Rectangular Solid Sterling Si... by Otis Jaxon Silver Jewellery £289.75$518.73€349.52$388.90 Geometric Pentagon Solid Sterling Silver B... by Otis Jaxon Silver Jewellery £89.75$160.67€108.26$120.46 30% OFF Silver Wire Wrapped White Pearl Stud Earrings by Otis Jaxon Silver Jewellery £29.75$53.26€35.88$39.93 £20.82$37.27€25.11$27.94 Sterling Silver Russian Wedding Band Ring by Otis Jaxon Silver Jewellery £26.75$47.89€32.26$35.90 30% OFF Silver Caged White Pearl Necklace by Otis Jaxon Silver Jewellery £29.75$53.26€35.88$39.93 £20.82$37.27€25.11$27.94 view all you may also like PRODUCT DETAILS CUSTOMER REVIEWS DELIVERY RETURNS ask seller a question save for later Flat wire bands hand-crafted to look like a belt are connected by a hinge mechanism which locks closed the bangle with an ingenious silver buckle. A timeless classic that continues to be a favourite with women of all ages and one our original designs from back when we started out twenty years ago! As this bangle opens and does not have to be slid on over the hand one size fits all! All Otis Jaxon jewellery is designed and assembled in the UK. Otis Jaxon use only exceptionally high quality sterling silver in our designs. We have for many years worked with the same small team of craftspeople who are directly employed by our company and all of whom we know on first name terms. We use Royal Mail 1st Class post to deliver our items, which has a delivery estimate of 1-2 working days. Whilst most items arrive within this timeframe, this cannot be guaranteed – please be patient if your order takes a little longer to get to you. All Otis Jaxon pieces will be beautifully presented in our signature branded packaging. made from: Made from Sterling Silver To keep clean we recommend using only a specialised silver polishing cloth. Never wear silver jewellery when swimming or bathing. dimensions: Approx: 6 cm X 4.3 cm product code: 180852 1 customer review read about our product rating system ratings guide trusted independent customer feedbackforum excellent bad good poor This product is dispatched to you by Otis Jaxon Silver Jewellery. MAINLAND UK order now and receive this item by price Standard Delivery Friday 29 July £2.75$4.92€3.31$3.69 Tracked Two Day Delivery Friday 29 July £6.70$11.99€8.08$8.99 Tracked Next Day 1pm Delivery Thursday 28 July £9.70$17.36€11.70$13.01 Saturday Delivery Saturday 30 July £15.70$28.10€18.93$21.07 NON-MAINLAND UK estimated delivery price Highlands & Islands of Scotland 2-5 working daysfrom dispatch £2.75$4.92€3.31$3.69 Northern Ireland 2-5 working daysfrom dispatch £2.75$4.92€3.31$3.69 Other UK Islands 2-5 working daysfrom dispatch £2.75$4.92€3.31$3.69 INTERNATIONAL DELIVERY estimated delivery price Western Europe 2-5 working daysfrom dispatch £11.50$20.58€13.87$15.43 Rest of Europe 5-10 working daysfrom dispatch £11.50$20.58€13.87$15.43 USA & Canada 5-10 working daysfrom dispatch £18.50$33.12€22.31$24.83 Asia & Australasia 5-10 working daysfrom dispatch £19.50$34.91€23.52$26.17 Rest of the world 5-14 working daysfrom dispatch £19.50$34.91€23.52$26.17 You have 28 days, from receipt of cancellable goods, to notify the seller if you wish to cancel your order or exchange an item. Please note: goods that are personalised, bespoke or made-to-order to your specific requirements, perishable products and personal items sold with a hygiene seal (cosmetics, underwear) in instances where the seal is broken are non-refundable, unless faulty. Read more about our returns policy.Should you choose to return or exchange your order you will need to deliver the item(s) to the UK, where this seller is based. Otis Jaxon Silver Jewellery's return policy Please see notonthehighstreet.com's returns policy.


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Position has an emphasis in print graphic design, web design, and marketing tools. Job Summary for the Graphic Designer- Digital and Print Media*....
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Excellent writing and communication skills. This position works closely with the New York Executive team and Marketing Coordinator in a fast-paced,...
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Social Media Marketing. We are a fast-growing Clearwater based technology company seeking a full-time, experienced graphic designer....
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Coordinate written and visual communication needs with graphic designer; Writing & Editing*. Writing, editing and publishing;...
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The Graphic Designer is solely responsible for conceptualizing, writing, designing, producing, and maintaining a portfolio of creative print and digital...
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Collaborate with Business Analysts, internal Account Executives, Copywriters and Graphic Designers to help formulate marketing strategy....
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Velocity Merchant Services - Downers Grove, IL
This position is perfect for a marketing student! An energetic, smart, motivated, creative entry-level marketing professional to support our marketing...
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Graphic Design & Brand Development. Minimum 5+ years experience as a Graphics designer, writer or creative and/or similar role in corporate communications,...


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