text:
Titration of non-replicating adenovirus as a vector for transducing active TGF-β1 gene expression causing inflammation and fibrogenesis in the lungs of C57BL/6 mice
Version of Record online: 13 DEC 2002
DOI: 10.1046/j.1365-2613.2002.00229.x
International Journal of Experimental Pathology
Volume 83, Issue 4, pages 183–202, August 2002
Additional Information
How to Cite
Warshamana, G. S., Pociask, D. A., Fisher, K. J., Liu, J.-Y., Sime, P. J. and Brody, A. R. (2002), Titration of non-replicating adenovirus as a vector for transducing active TGF-β1 gene expression causing inflammation and fibrogenesis in the lungs of C57BL/6 mice. International Journal of Experimental Pathology, 83: 183–202. doi: 10.1046/j.1365-2613.2002.00229.x
Publication History
- Issue online: 13 DEC 2002
- Version of Record online: 13 DEC 2002
- Received for publication 4 January 2002 Accepted for publication 10 July 2002
- Abstract
- Article
- References
- Cited By
- adenovirus vector;
- cell proliferation;
- collagen;
- fibrogenesis;
- TGF-β1 gene expression;
- lung inflammation;
- pro-α 1 (I)
Investigators have shown that interstitial pulmonary fibrosis (IPF) can be induced in rats by overexpressing transforming growth factor beta1 (TGF-β1) through a replication-deficient recombinant adenovirus vector instilled into the lungs (Sime et al. 1997). We have shown that this vector induces IPF in fibrogenic-resistant tumour necrosis factor alpha-receptor knockout (TNF-αRKO) mice (Liu et al. 2001). The object of our studies is to understand how peptide growth factors, such as TGF-β1, mediate interstitial lung disease (ILD). To do so, we must be able to manipulate the dose of the factor and sort out its effects on multiple other mediators in the lung parenchyma. As a step in this complex process, in the studies reported here, we have determined the concentrations of the recombinant adenovirus vector carrying the gene for porcine active TGF-β1 (AVTGFβ1) that have little apparent effect, cause clear induction of disease, or severe disease. The disease largely resolves by 28 days in all cases, thus providing a valuable model to understand the mechanisms of the IPF that is mediated, at least in part, by TGF-β1. The findings here show that 106 plaque-forming units (pfu) of AVTGFβ1, provide essentially a 'no-effect' dose, but even this amount of TGF-β1 causes a significant increase in whole-lung collagen by day 28 after treatment. In contrast, 108 and 109 pfu cause severe IPF in 4 days, whereas 107 and 5 × 107 are intermediate for all parameters studied, i.e. TGF-β protein, inflammatory cells, cell proliferation, pro-α 1(I) collagen gene expression and whole-lung collagen accumulation, and expression of growth factors such as TGF-β1, TNF-α and PDGF-A and -B. Interestingly enough, TGF-β1, as a potent blocker of epithelial cell proliferation, appears to suppress airway epithelial cell growth that would be expected during the inflammatory phase of IPF. Thus, this model system helps us to understand some quantitative aspects of TGF-β1 biological activity and allows us to manipulate this potent factor as a mediator of interstitial fibrogenesis.


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The new home of
5 reviews
This magnificent converted detached barn on three levels abounds with elegance, style and comfort to provide a peaceful holiday haven in rural tranquillity. Featuring French oak beams, Lake District slate, lots of exposed stonework, and granite work surfaces in the large kitchen, the barn provides masses of space for couples or family groups. Surrounded by pasture land and woods there are many walks direct from the door down to the Edwardian coastal town of Grange-over-Sands, 2 miles, which has all facilities and two golf courses, or across country to the picturesque village of Cartmel, 4 miles, with its 14th-century priory, many pubs and restaurants, and annual horse racing events. Behind the barn are stabled some 'resting' racehorses, which can be seen grazing with sheep and cattle in the 25-acre grounds. Holker Hall, gardens and museum, Sizergh Castle and Levens Hall are within 8 miles, whilst Lake Windermere is just 5 miles with the Lake Cruiser, Aquarium of the Lakes and the Lakeside to Haverthwaite Steam Railway. This southern area of the Lake District National Park hosts a multitude of visitor attractions as well as beautiful Lakes and stunning fells for walking and climbing. This property is under the same ownership as Miller Beck (LN4). Shops and pub 2 miles. This property accommodates a maximum of 8 guests.
Large dining room. Large kitchen with TV, wood-burning stove, electric range, breakfast area, granite work surfaces, feature stained glass window, wooden floor and beams. Second small kitchen. Utility. Double bedroom. Fully tiled shower room and toilet. First floor: Beamed double bedroom with 5ft bed and en-suite bathroom with roll-top bath, shower cubicle, toilet and bidet. Two further double bedrooms, one with en-suite bathroom with toilet and bidet, one with en-suite shower room and toilet (access also from landing). Single bedroom (for alternative sleeping only) with additional pull-out bed (for alternative sleeping only). Open-tread stairs to second floor: Spacious living room with games area and superb views over Morecambe Bay. Four steps down to conservatory with pool table. Maximum occupancy 8 including infants.
4 reviews
Overlooking Clovelly Bay Marina at Mount Batten, this superb holiday property is a stylish townhouse on the waterfront, with the superb Mount Batten Watersports and Activities Centre, and Plymouth Sailing School right on your doorstep. The property boasts two balconies, one off the kitchen/dining room on the ground floor, and the second balcony off the living room on the first floor. Both are fabulous spots in which to sit and watch the boats coming and going. The kitchen is very modern and bold, the bedrooms cool and contemporary and the bathrooms well-equipped with the master bedroom en-suite featuring a spa bath. This is a lovely home for a family wanting to enjoy the local facilities. It isn't just a summer destination but a great base for winter weekends or a spring break.In Mount Batten there are two waterside pubs and a little beach, and Bovisand Beach with cafe and parking is just a 5-minute drive away. The South West Coastal Path runs along the front of the property, and you can walk to Turnchapel, which is a little historic riverside village, or along the cliff path to Jennicliffe, with its popular café perched on the headland with the most spectacular views across Plymouth Sound to Mount Edgecumbe in Cornwall on the far side of the bay. From Mount Batten you can catch a little water taxi across to Barbican, with its cobbled streets, restaurants, bars and shops. Here you will find the marine aquarium and the historic waterfront area of Plymouth Hoe, with its iconic outdoor swimming pool lido and panoramic views. The peninsula at Mount Batten itself is a historic site. It was formerly an RAF station for sea planes and the base in the 1930s for Aircraftsman Shaw, better known as Lawrence of Arabia. Beach 100 yards. Shop 2½ miles, pub 50 yards and restaurant 100 yards.
Ground floor: Dining room/kitchen with patio door. Utility room. 1 single bedroom. Separate toilet. All rooms with wooden floor. First floor: Living room with patio doors. 1 twin bedroom with en-suite shower room and toilet. Second floor: 2 double bedrooms with shared en-suite bathroom with spa bath and toilet, one with stairs to third floor: 1 single bedroom with wooden floor, Velux and en-suite shower room and toilet.
Gas central heating, electricity, bed linen and towels included. Three Freeview TVs (one 42"). DVD and small library. Book library. Gas hob. Electric oven. Washing machine. Tumble dryer. Dishwasher. Fridge/freezer. Wi-fi. Balconies with furniture. Parking (2 cars). No smoking. Couples and family bookings only. NB: Waterfront location.
19 reviews
Set in a picturesque National Trust village
This well-appointed and beautifully presented holiday home is set over three floors and offers a very good level of comfort with attention to detail. It is situated in the stunning NT village of Corfe Castle, which stands at the gateway to the Isle of Purbeck and is dominated by the ruined castle - a delight at any time of year. Family attractions include a model village and interactive exhibition, a steam railway and many interesting shops. Corfe Common is found at the edge of the village, with the Purbeck Way walking route passing through it to reach Chapman's Pool and the South West Coastal Path. The village itself is constructed almost completely from the local grey Purbeck limestone and a small collection of shops, the post office, church and pubs cluster around the village square, which is just a stroll from the cottage. The Jurassic coastline is a short drive away, with famous Lulworth Cove and Durdle Door. The seaside town of Swanage with its boat trips, Durlston Country Park and steam railway, Monkey World and The Tank Museum are also close by. Beach 4 miles. Shop ½ mile, pub/restaurant ¼ mile.
Ground floor: Living room. Dining room/kitchen with laminate floor. Shower room with toilet. First floor: 3 bedrooms: 1 double, 1 twin, 1 single (4ft). Bathroom (no toilet). Separate toilet. Second floor: 2 bedrooms: 1 double, 1 single, both with Velux.
Gas central heating, electricity, bed linen and towels included. Travel cot. High chair. Satellite TV (basic package). DVD. CD. iPod dock. Gas hob. Electric oven. Microwave. Washing machine. Tumble dryer. Dishwasher. Fridge/freezer. Wi-fi. Enclosed, lawned garden with patio, sitting-out area, terrace and furniture. Children's play area with swing, slide and rocker. Gas barbecue. Parking (3 cars). Cycle store. Welcome pack. No smoking. NB: 3 steps in garden.
7 reviews
Set amidst a wooded valley with a tranquil stream running alongside it, Provender House is the quintessential detached country house, the original mill stone now forms the doorstep and the pretty garden is edged by the stream. A short walk through woods to the beach is highly recommended. The pretty village of Veryan, which sits on the edge of the Roseland Peninsula is minutes away and offers a wonderful local pub serving local ales and food, a gallery and a shop. Along the peninsula visitors can find many beaches including Pendower and Carne, considered to be amongst the prettiest in Cornwall. There are also fishing villages with the day's catch which guests can buy for that special meal or simple barbecue on the beach. The area is renowned for its beauty and dramatic coastline which provides hours of walking with stunning views across the open sea or inland across rolling fields. There is horse riding, golf and cycling within easy reach of the village. Further afield is Fowey, Truro, Padstow, St Ives and Falmouth which can be reached by passenger ferry from nearby St Mawes. The Eden Project and the Lost Gardens of Heligan are easily reached and both well worth a visit. Truro has a theatre, cinema, a museum, plentiful local restaurants and excellent shopping. Falmouth has the historic docks and is home to the National Maritime Museum, with many hands-on exhibits for children of all ages. Pleasure cruises around this picturesque bay can be enjoyed, as can kayaking, river trips to Truro or simply meander the narrow streets. There are many cycle trails in the area many of which are linked and are mainly off road. Cycle hire centres are available and it is possible to cross the county by bike, or cycle through the Cornish industrial heritage sights and marvel at the ancient tin mines. The beaches of the peninsula and Cornwall are second to none and provide the ultimate day out for little cost. Rock pooling, crabbing and fishing as well as lazing on the fine white sand are all recommended. Shops and pub ¾ mile.
Large farmhouse-style kitchen with breakfast area, slate floor and large dining area/conservatory with patio doors to garden and tiled floor. Utility. Bathroom with separate shower cubicle and toilet. Double bedroom with 5ft bed and garden view leading to two single bedrooms. First floor: Large living room with wood-burning stove. Double bedroom with en-suite shower room and toilet. Twin bedroom with 2ft 6in beds (for +2 children).
10 reviews
Two minutes walk from the beach and estuary in Alnmouth, this charming spacious, family-size holiday home with a private terraced garden for relaxing, offers tasteful accommodation in the centre of this charming picturesque village. On the main drive through, and surrounded by friendly pubs and shops in this sought after destination, this elegant and cosy house will delight all ages. The village is widely photographed for its Balamory style houses and stunning estuary location. Alnmouth is on the main heritage coastal route within an AONB with miles of stunning coastline and castles to explore. Nearby Alnwick, the ducal town with its majestic castle used in Harry Potter's Hogwarts, enchanting water gardens and cobbled streets will delight all the family. Close by is Warkworth, another popular village with its castle ruins, tea shops and galleries, which can be reached on foot for enthusiastic walkers (approx 2 miles). Stunning walks can be taken along the coastline on this stretch of the coast, and Bamburgh with its fortress of a castle should not be missed. Littlecroft is centrally located for all the North East attractions and is only 2 minutes from the mainline station and good bus service. Golf course in village. A perfect base for exploring this friendly county. Shop 50 yards, pub and restaurant 10 yards.
Ground floor: Living room. Second living room/dining room/kitchen. Utility room. 1 single bedroom. Separate toilet. First floor: 4 bedrooms: 3 double, one with en-suite bath, one with en-suite shower room and toilet, 1 single. Bathroom with bath and shower cubicle.
Open fire in living room included. Gas central heating, electricity, bed linen and towels included. Travel cot and high chair on request. Two Freeview TVs. DVD. iPod dock. Electric cooker. Microwave. Washing machine. Dishwasher. Fridge/freezer. Wi-fi. Enlcosed terraced garden with patio and furniture. Garage (1 car). Parking (1 car). No smoking. NB: Garden has 6 steps to lawned area then a further 5 steps to top level.
3 reviews
Ground Floor: The property has gas central heating and comprises:Lounge: Large with laminate floor, electric log-effect fire, 32" Freeview TV, DVD player, CD player and Wii console.Open plan living space.Kitchen area: With tiled floor, electric oven, electric hob, fridge/freezer, dishwasher, washing machine, tumble dryer and patio doors.Dining area: With patio doors.Gaming area: With pool table, games and books.Cloakroom: With WC.
First Floor: Bedroom 1: With twin beds.Bedroom 2: With single bed.Bathroom: With shower over bath, WC and heated towel rail.Shower room: With shower, WC and heated towel rail.
Second Floor: Bedroom 3: With double bed.Bedroom 4: With twin beds.Bedroom 5: With single bed.
All gas, electric, bed linen and towels included. Travel cot, highchair and stairgate available on request. Wi-Fi.Small courtyard. Parking permit for 2 cars free of charge. No smoking.
6 reviews
"Sands flanked by rock, with wooded cliffs above – true Devon coastal character . . ."
The wooded cliffs at Bolt Tail form a backdrop to this sandy cove on what is renowned as one of the most beautiful stretches of coastline in the South Hams. These holiday cottages are set within 100 yards of the safe sandy beach – an unrivalled position for enjoying the seaside, but also perfect for fishing, sailing and water-skiing (with a dinghy-launching slip 200 yards away, and facilities for larger boats at nearby Salcombe). The cottages are in the centre of this charming seaside village, with its pretty thatched cottages, inns, restaurants and small shop within a short walk. The South Devon Coastal Footpath winds along the cliffs and through Hope Cove between Salcombe and Thurlestone, with opportunities for magnificent walking amongst glorious coastal scenery.The maritime attractions continue slightly further afield. Salcombe, 4 miles away, is one of the most prestigious sailing centres in the country. It offers extensive sandy beaches, too, and a wide choice of fascinating shops, boutiques and restaurants in its quaintly winding narrow streets. The estuary here is a kaleidoscope of brightly coloured craft of all kinds at their moorings – a paradise for sailing enthusiasts. Thurlestone, 2 miles to the west, can be reached either by car or via the coastal path. It boasts yet more expanses of golden sands, a regular feature of this lovely coastline. But, in addition, it has a superb cliff-top links golf course, edged by sandy coves, tennis courts and picturesque streets of thatched cottages overlooking the bay. Kingsbridge, the 'capital' of the South Hams, has a good choice of interesting shops, a museum and a sports centre with squash, badminton and bowling. Boating and diving trips can be arranged in the Salcombe Estuary, and boats are available for hire. Within easy driving distance are the historic cities of Plymouth and Exeter and Kitley Caves. The wide open spaces and breathtaking scenery of the Dartmoor National Park are less than an hour by car, and there are many National Trust properties, stately homes and interesting gardens within a short drive. Anchor Cottages are set in a little terrace in the village. They have been designed to offer 'upside-down' accommodation, with first floor living rooms. Comfortably furnished, each has a small first floor sitting-out area with furniture. They are ideally located for a Devon holiday by the sea. Shop/P.O. 50 yards.
Entrance hall. Four attractive bedrooms; two twin and two single. Bathroom with over-bath shower and toilet. Open-tread stairs to first floor: Comfortable, open-plan living/dining room with elec fire and doors to the patio. Well-equipped kitchen area with d/washer and m/wave. Double bedroom with en-suite bathroom with electric over-bath shower and toilet. Separate toilet.
3 reviews
Ground Floor: The property has underfloor oil central heating and comprises:Lounge: Spacious with wood floor, multi fuel burner, patio doors and 40" Sky TV.Dining room: Spacious with wood floor and patio doors.Kitchen: Spacious with slate floor, breakfast area, electric oven and hob, microwave, fridge/freezer and dishwasher.Second lounge.Utility room: With washing machine and tumble dryer.Cloakroom: With WC.Bedroom 1: With single bed and en-suite wet room with WC.
First Floor: Bedroom 2: With king size bed, TV and en-suite shower and WC.Bedroom 3: With zip and link super king size bed and en-suite shower with WC.Bedroom 4: With single bed.Bedroom 5: With double bedroom and en-suite with shower and WC. Bathroom: With bath and WC.
All power, bed linen and towels included. First basket of logs for multi fuel stove provided. Travel cot and highchair available. Bike storage available. Large enclosed garden with patio, terrace and garden furniture. Landscaped grounds. Parking for two cars and additional on street parking for one car. Please note: there are several steps and unfenced stream and pond within the garden and grounds.
4 reviews
Ground Floor: Property has gas central heating and comprises; Lounge; With TV/Freeview, DVD, Wi-fi and gas fire with seating for 8. Dining Room: With table and chairs to accomodate 8. Kitchen: With double gas and electric oven, gas hob, microwave, integrated fridge/freezer and dishwasher. Utility: With washing machine Cloakroom; With WC and wash basin.
First Floor: Bedroom 1: With king size bed, TV and en suite shower, wash basin and WC Bedroom 2: With double bed Bedroom 3: With single bed Bathroom: With bath and shower over, WC and wash basin
Second Floor: Bedroom 4: With small 4ft double Bedroom 5: With twin beds
All power, heating and bed linen included.Enclosed garden with garden furniture. Parking available on driveway of property. Although the property has bed spaces for 9, the maximum is 8 and the additional bed space for offering alternative sleeping arrangements.
14 reviews
Ground Floor: The property is heated by gas central heating and comprises:Kitchen: Gas range cooker with side electric oven, gas hob, microwave, fridge/freezer, dishwasher and washing machine.Lounge: TV/Freeview, DVD, radio/CD player and electric fireDining Room, Conservatory and small playroom/music roomBedroom 1: King size bedroom. Bedroom 2: Single bedroom.Bedroom 3: Single bedroom.Bathroom: Bath with shower attachment, basin and WC.
First Floor: Bedroom 4: Double bedroom.Bedroom 5: Twin bedroom.Shower room: With shower, basin and WC.Lounge: With TV.
All heating, bed linen and towels are provided. Cot and Highchair available.Two well behaved pets welcome. Parking for 3 cars.
2 reviews
This semi-detached house is ideally located overlooking the beautiful gardens and boating lakes of Peasholm Park. Wander through the park to the North Bay and stroll along to the South Bay where all the fun of the seaside can be enjoyed with boating trips, fishing trips, a fun fair, amusement parks and donkey rides on the beach or take the open top bus and enjoy breathtaking views. Bring the surf boards and enjoy the waves in the North Bay where the award winning beaches are overlooked by the 12th-century castle ruins and St Mary's Church. Scarborough caters for all ages with an eclectic mix of shopping in the town centre, an 18-hole cliff top golf course, the Stephen Joseph theatre, inns and tea rooms to suit all tastes. The Cleveland Way runs along the cliffs towards Filey and the Bempton RSPB bird sanctuary. The ancient sea port of Whitby, from where Captain James Cook set sail on his epic journey, is home to the North Yorkshire Moors steam train and it's well worth the trip through the moors to the 'Heartbeat' village of Goathland. Take a leisurely drive to the North York Moors and discover pretty villages tucked away deep in the valleys. Cyclists visit Dalby Forest, home to the world mountain bike event, and perfect for a family day out with Go Ape, picnic areas, a visitor centre, play areas and open air music festivals. Lake View really is an ideal location for exploring both the North York Moors and the Heritage Coast of East Yorkshire. Shop and restaurant 200 yards, pub 500 yards. Can be booked with ref 25195 to accommodate up to 14 guests.
Ground floor: Living room. Dining room. Kitchen. Sun room. Games room. Shower room. First floor: 3 bedrooms: 1 double (5ft), 1 twin, 1 single. Bathroom with bath and shower cubicle. Separate toilet. Second floor: 2 bedrooms: 1 double, 1 single.
Electric coal-effect fire in living room included. Electricity pebble-effect fire in dining room included. Gas central heating, gas, electricity, bed linen and towels included. Cot. High chair. Freeview TV. DVD and small library. CD. Halogen hob. Electric oven. Microwave. Washing machine. Tumble dryer. Dishwasher. Fridge/freezer. Wi-fi. Enclosed lawned garden with sitting-out area and furniture. Barbecue. Parking (2 cars). Games room. Welcome pack. No smoking.
14 reviews
"Devon's best kept secret... Just inland from some of Devon's loveliest and most natural beaches lies the village of Tuckenhay set along Bow Creek on the River Dart...."
In a setting of stunning natural beauty, Tuckenhay Mill is the centrepiece of a cluster of country homes and cottages with superb leisure facilities including two indoor and one outdoor pools, making it ideal for a family holiday for all ages.The Mill which once produced some of the finest paper in the land, nestles in the green and shady Bow Creek, a languid inlet of the River Dart where private yachts have replaced the old tall-masted ships and barges. Around the mill are all the buildings which once went to make up a small bustling village port. These listed buildings have been sympathetically restored and converted to a delightful range of holiday properties to suit larger family parties. Awards have been won for the conversion of buildings and the conservation of the area. With so much to do, many holidaymakers return year after year.South Devon awaits you Tuckenhay is only a 20-minute drive from the superb award-winning beach at Blackpool Sands and about 30 minutes from a surfing beach at Bantham, as well as some of the best natural beaches to be found anywhere in the UK.There is also extensive access to the coastal footpath for walking and the wilderness that is Dartmoor for walking, climbing and riding.This is a mecca for ramblers, bird-watchers, swimmers, surfers, horse riders, golfers and those interested in fishing, boating, sailing and windsurfing.In addition, there are many historic NT houses to visit including Agatha Christies's Greenway as well as a local vineyard (with award-winning wines) at Sharpham.Tuckenhay is only 5 miles inland from Dartmouth and 3 from the market town of Totnes. Village shop 3½ miles. Riverside inn and restaurant within walking distance.A superb choice of cottagesEach of the cottages has been individually styled to offer comfortable and spacious accommodation. Great care has been taken to retain the feel of the original buildings and extensive use has been made of traditional materials. Most have garden, terrace or patio. Individual cottage details are shown on the following pages.Many cottages have more than one bathroom and some have an en-suite bathroom to every bedroom. Kitchens are comprehensively equipped: most have dishwashers and all have microwave cookers.Couples and honeymooners will feel snug and comfortable in the small cottages: Mill Leat, Mill Stream and Mill Spring. Families can spread out in Papermaker's or Turbine Cottages, while Mill Lodge, Edgecombe Barn and Tuckenhay Mill House will sleep larger parties in comfort. Of course, combinations of cottages can accommodate bigger gatherings of family or friends.
An attractive detached stone-built house enjoying a delightful position facing west at the entrance to Tuckenhay Mill with a pleasant rural outlook. Entrance hall with oak floor and impressive staircase. Period-style living room with open fire. Conservatory opening on to private garden and patio area with BBQ. Fully fitted kitchen with arch to dining room. Pretty single bedroom with adjacent shower room and toilet. First floor: Double bedroom with en-suite bathroom. Two large twin bedrooms. Single bedroom. Second bathroom. Separate toilet.
THE TUCKENHAY POOLSTuckenhay is renowned for its spectacular award winning indoor pools with glass mosaics and hand-painted silk murals, they combine exotic decoration with the most modern dehumidification and purification equipment and full changing facilities.ROMAN POOLThis dramatic Roman style 32ft pool (4ft 6in deep) has a safe children's bay reached by separate steps. Completing the experience are sauna and steam room (£1 by slot meter), a refreshing cool drench shower fed from the underground spring and a separate Jacuzzi with hydro jets. Open daily from 8.30 am to 8.30 pm. Children must be supervised.WATERFALL POOLThis award winning pool is sculptured in a curved shape over 40ft long (4ft 6in deep), and bounded in part by a natural grotto rock face of tumbling water. It incorporates the ultimate in water movement technology: floor and wall massage jets, water volcanoes, water cannons and swim jets. There are two Jacuzzis - one in the pool - sauna and steam room (£1 by slot meter) and hot and cold spring-fed showers.Separate mother and baby changing facilities with walk-in shower/wet room. Open daily from 8.30 am to 6.30 pm. Adults and children over ten with a swimming adult.The extra charge for use of pools and heating, detailed in the cottage descriptions is all inclusive in the final balance.HEATED OUTDOOR POOL - with heated hot tub with sauna and drench showerThis 60ft pool (3ft - 6ft 6in deep) has landscaped riverside sunbathing terrace and sloping lawn to stream. Open daily 8am to 8pm (1 May–1 Oct). Children must be supervised.
IN SYMPATHY WITH THE ENVIRONMENTTuckenhay Mill has led the way with most of the pools being heated by ground source heat pumps. Awards have been given for energy saving as well as pool design and conversion of buildings. 2008 saw the extension of the 20 acres of stunning natural landscape opening up nearly a mile of footpaths through dells, meadows and woodlands along with a natural waterfall. This is the place to enjoy a personal 'Spring or Autumn Watch' with swallows in the log store, buzzards on the adjacent hillside, owls in the woods and ducks and swans down on Bow Creek. Strolls can be taken with the dog and picnics enjoyed on a bench by the river. Children can stroke the goats and even collect eggs for breakfast from the hens (when laying)!
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Frequency Domain Hybrid Finite Element Methods in ElectromagneticsMorgan & Claypool Publishers 2006; US$ 40.00
This book provides a brief overview of the popular Finite Element Method (FEM) and its hybrid versions for electromagnetics with applications to radar scattering, antennas and arrays, guided structures, microwave components, frequency selective surfaces, periodic media, and RF materials characterizations and related topics. It starts by presenting... more...
Fundamentals of Electromagnetics 1Morgan & Claypool Publishers 2007; US$ 36.00
This book is the first of two volumes which have been created to provide an understanding of the basic principles and applications of electromagnetic fields for electrical engineering students. Fundamentals of Electromagnetics Vol 1: Internal Behavior of Lumped Elements focuses upon the DC and low-frequency behavior of electromagnetic fields within... more...
Fundamentals of Electromagnetics 2Morgan & Claypool Publishers 2007; US$ 32.00
This book is the second of two volumes which have been created to provide an understanding of the basic principles and applications of electromagnetic fields for electrical engineering students. Fundamentals of Electromagnetics Vol 2: Quasistatics and Waves examines how the low-frequency models of lumped elements are modified to include parasitic elements.... more...
Applications of Advanced ElectromagneticsSpringer Berlin Heidelberg 2012; US$ 279.00
Rich with examples and illustrations, this book surveys advances in electromagnetics: electromagnetic?quantum equations in modeling of microwave-quantum integrated circuits, topological methods for analyzing the boundary value problem and many more innovations. more...
EPR of Free Radicals in Solids ISpringer Netherlands 2012; US$ 349.00
In its updated 2nd edition, this book surveys methods and applications of EPR in the study of free radical processes in solids. The focus is on trends in methods for extracting structural and dynamical properties of radicals and spin probes in solid matrices. more...
High Frequency Processes in Magnetic MaterialsWorld Scientific Publishing Company 1995; US$ 128.00
This review volume deals with recent advances in topics of importance to scientists and engineers involved in research and device development utilizing magnetic oxides and multilayers. The subject matter covered includes linear and nonlinear high frequency magnetic excitations and interaction between magnons and photons. In particular, this book contains... more...
Nuclear Acoustic ResonanceElsevier Science 2012; US$ 72.95
Nuclear Acoustic Resonance serves as an introduction to the field of nuclear acoustic resonance and highlights its differences from nuclear magnetic resonance. Topics covered range from the nature of the coupling mechanisms, including dynamic electric quadrupole coupling and dynamic Alpher-Rubin coupling, to experimental techniques. The application... more...
Advances in Magnetic ResonanceElsevier Science 2012; US$ 72.95
Advances in Magnetic Resonance: The Waugh Symposium, Volume 14 is a collection of manuscripts presented at the 1989 symposium on ?High Resolution NMR in Solids, held at the Massachusetts Institute of Technology. The contributors provide 20- to 30-page articles consistent with AMR?s traditional emphasis on quantitative analysis of NMR techniques. Organized... more...
Rare Earth Permanent MagnetsElsevier Science 2012; US$ 72.95
Rare Earth Permanent Magnets presents the discussion of the metallurgy and properties of rare earth permanent magnet alloys. The monograph initially provides the elementary aspects of magnetism to enable the reader sufficient understanding of permanent magnetism. The book then discusses the rare earth elements and their alloys with cobalt, copper,... more...
Relaxation in Magnetic ResonanceElsevier Science 2012; US$ 72.95
Relaxation in Magnetic Resonance contains a series of lecture notes for a special topics course at the University of South Carolina in 1967. This book contains 21 chapters that summarize the main theoretical formulations and experimental results of magnetic resonance relaxation phenomena in several physical systems. This text deals first with the... more...


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LOT #5572 |Sold for: Sign-in or Join (free & quick)
1914-D 10C MS67 NGC....Click the image to load the highest resolution version.
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Colorful Superb Gem 1914-D Dime1914-D 10C MS67 NGC. Lime, apricot-gold, plum-red, and deep green encompass this lustrous Superb Gem. The surfaces are immaculate, the strike is precise aside from the right termination of the wreath. The 1914-D is readily available in most grades but becomes an important type coin at the MS67 level. Census: 7 in 67, 1 finer (11/11).(Registry values: N2998) (NGC ID# 23FU, PCGS# 4866)
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Chem-Dry of Aiken County - North Augusta, SC - Phone: (803) 278-6050
Eubanks Janitorial Service - North Augusta, SC - Phone: (803) 279-9682
Small appliances are small tools which are movable and are generally kept on tabletops, wooden platforms, etc. Like the major appliances, small appliances also assist in making work easier. In North Augusta, maximum small appliances use electricity for their operation. Some appliances also work on batteries. In North Augusta, small appliances like blenders, toasters, juicers, etc, are widely used as they are quite handy to use and make the job at hand to finish off at a fast rate. They are not only used at homes but also for commercial purpose like restaurants, offices, etc. Small appliances are quite cheap and in North Augusta they find their usage in many household.
Governor Cuomo Announces First Solar Schools Project At The New York Institute For Special Education In The Bronx
Governor Cuomo's K-Solar Program Increases Use of Renewable Energy in Schools (New York, NY) Governor Andrew M. Cuomo today announced the New York Institute for Special Education in the Bronx will be the site of the state's first solar schools project and will have solar panel arrays installed thanks to a power purchase agreement with SolarCity. This public-private partnership is..


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Is there any way my graphic card , or any of the sata drives are causing psu to
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Gay Christian group welcomes assurances from Archbishop of Canterbury on Uganda's anti-gay bill
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Reader comments
Whoppee! He's had how long to condemn Uganda's homophobic bill? Don't feel you need to rush, in fact a snail can run the 100 metre dash faster than statements about this issue come out of the Church of England's offices.
Too little too late. The lengthy delay in his condemnation unfortunately still shouts louder than any statement he has now actually issued.
Rowan Williams is a coward, a disgrace and an embarrassment to his church. The proposed new law in Uganda which will legalise genocide needs to be condemned loudly.
Why has that pathetic loser Rowan Williams not instructed the Anglican church in Uganda to condemn it? Oh yeah – because the Anglican bigots in Uganda support it.
Why has that waste of space Williams not told the Anglican hierarchy in Uganda that they will be expelled from the Anglican church unless they condemn the proposed genocidal laws?
Because he values keeping his church together more than he values human life.
Rowan Williams is proof (if any were needed) of the poisonous, 2-faced, murderous attitudes of even so-called 'liberal' religion.
He is contemptible.
Simon, never ever trust as I know you don't, what I call vanilla ice cream liberals. They can talk a good game but never take the field to play it! In the US the Anglicans only get angry at other Anglicans if They get angry, indeed it is the Only transgression that can get you kicked out of the American Episcopal Church. At the moment on this side of the Pond the Anglicans are bitterly fighting over property and the monies it represents. Where your treasure is there is your heart, that is where any groups true values lie no matter what spin or hype may be the contrary!
Simon Murphy,
I totally agree that Rowan williams is a Coward, Homophobic and a disgrace to the office he holds. An academic such as Williams should never be elected or appointed to boss of the Anglican Church. His mind is far too cluttered with Religious fodder to make rational decisions especially towards Gay Rights.
The Catholic church has been strangely silent on this matter as well. I just wonder if the ex Nazi Pope has his hand behind this bill as Uganda is mainly a Catholic country.
Yes good point Abi1975! Its not like the Arch Homophobe of Rome to keep his gob shut is it? Maybe he's just rubbing his beringed hnds in glee that the Ugandan Govt is carrying out His evil plans(!)for him……
Not that I believe in religion, but Dr. Williams has been negotiating with the head of the Anglican Church in Uganda for the last 6 months. The Ugandan Archbishop squarely told Williams that Canterbury needs to stop supporting the ordination of gays and return to the anti-gay "gospel values", otherwise the church in Uganda would formulate its own agenda… but without splitting from Canterbury.
So for the Archbishop of Canterbury to condemn the proposed anti-homosexual bill presently being debated in Uganda is tantamount to condemning the direction the Anglican church has taken in Uganda.
Oh, and Abi and Mike, I do believe ben16 is in the picture; he's laying out the red carpet for the 4,000+ Anglican ministers who have gone over to Rome just recently because of this issue.
There is no doubt where b16 stands regardless of how loudly he denounces the persecution of homosexuals. b16 has refused time and time again to update the RCC's sexual theology, especially in the catechism which is taught to children. Children are not born with hate in their hearts; they are taught to hate by the lovey-dovey persons around them.
Also, it cannot be repeated often enough that the Uganda Gov't is not acting unilaterally on this Bill; Rick Warren's American fundamentalists and members of "The Family" have been fanning the flames of homophobia in Uganda for well over a year, and the strangest thing is that nobody has mentioned the presence of Jihadists in Africa. Can of worms, or what!
Who's wicked? Who's benevolent? Don't ask me!
These comments are un-moderated and do not necessarily represent the views of PinkNews. If you believe that a comment is inappropriate or libellous, please contact us.
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15 of 15 people found the following review helpful
Verified Purchase(What's this?)
This review is from: Timex Women's T2N913 Weekender Mid-Size Slip-Thru Blue Nylon Strap Watch (Watch)
I have a small frame, and this watch manages to look normal sized on me. I am very pleased with it. The nylon strap is starting to wear some, but that is not a big deal. Timex makes multiple straps, so replacements are not only possible, they're opportunities to update your look without spending a bunch of money.
It does tick a little loudly, so if you plan on spending a lot of time along in silence, this may not be the best watch for you.
Review Details
Top Reviewer Ranking: 8,741,762


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Product Description
Do You Love True Crime Books? "Show No Fear" has all the action you need!
Show No Fear Redux
This is as close as the ordinary person will ever get or will ever want to get to the insular, dark and violent world of the nightclub bouncer. This is the real deal, a no holds barred account.
Bill is a good guy in tough world and you will see how the violence begins to alter his mind set.
"A short conversation or argument is generally the precursor to a fight, although sometimes your adversary can just start swinging after very little or sometimes no verbal sparring. There are some real nutters out there." Bill Carson.
So if you are ready grab your baseball bat, pull on your body armour, bite down on your gum shield and follow Bill on his journey and enter the shady, dangerous realm of nightclub bouncers. This book is preordained to be a cult classic, this is a must read, quite simply a bouncer's bible.
˃˃˃ Combat magazine book review. By Editor Malcolm Martin.
In 1993 Bill Carson was a night shift worker into weight training and martial arts, unhappy with his wage packet. That summer he decided to supplement his earnings with some door work, and kept a diary on the job.
What's the book about?
This is the result of that diary, a book that delves into the murky world of the bouncer from Bill's personal perspective. Bill worked the doors for five years and the book collects some of the more 'colourful' incidents during that period.
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If you like Geoff Thompson's earlier biographical work, then this will be right up your street. The book is full of vivid encounters, unsavoury characters and ripe language, told in a personable manner with a measure of wit.
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Goodreads review. Cayle.


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Siemens Gigaset SL565 Bluetooth phone
4.0 stars
Bluetooth, phone memory, stylish looking, colour screen
Paying for the Bluetooth element, colour screen could have been better, no SIM card reader to transfer over contacts
It was only a matter of time before landline handsets started introducing Bluetooth as part of their feature set. First was BT with its rather chav-esque BT Glide, now Siemens has waded in with the rather more stylish looking Gigaset SL565. But is it something we need?
The Siemens Gigaset SL565 is a stylish looking candy bar phone that features a multitude of features most notably the integration of Bluetooth so users can use the phone with one of those handsfree headsets that make you look like an extra out of Star Trek.
While we can fully understand the thinking behind using Bluetooth for a mobile phone we aren't sure that we are ready for it yet on our home phone.
But then the Gigaset SL565 is designed for the office not primarily the home and with that in mind it comes with so many features you may get weary looking or using all of them.
For starters there is its ability to send and receive text messages (service options applying) to four individual boxes with memory for up to 50 messages in each box for different members of your house.
Then there is its ability to store up to 250 contact entries complete with three numbers per entry (work, home and mobile presumably), plus email addresses and appointment details.
If that wasn't enough to convince, like a mobile, you can set specific ringtones or images to certain numbers so you can avoid the wife or the accountant depending on your mood and have them saved on the integrated answer machine which has a digital recording time of up to 35 minutes.
Expandable to up to six handsets all from the same base station the system can expand as you add more staff or rooms.
In use and the phone is easy to use, with a large 65k colour screen that makes reading text messages or numbers easy. It would have been nice to see a better quality screen, certainly as nice as the one in the picture (see right), but then you can't have everything.
Above the keypad, which is also easy to use are a series of quick buttons that allow you to access your messages, and options on the screen in a very similar way to a mobile phone.
Connecting a Bluetooth headset to the device was also easy and involved little effort while the Gigaset SL565 also supports you transferring contacts from another Bluetooth-enabled phone.
Gripes? Not many. We would have like to have seen a better screen, and a SIM card reader to transfer all our contacts from our mobile without having to do them one by one via Bluetooth, although both aren't going to affect you much in day to day operation.
In use call quality both receiving and making calls was very good. As for battery life, this too wasn't a problem as the heavy silver stand doubles as the charging station.
Overall a good performer for the small office with a price that won't break the bank, however you are paying the extra for the Bluetooth capabilities and unless you plan to wear a headset most of the time then there are cheaper better alternatives out there.
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Native Plants
Q. Who is Mr. Smarty Plants?
A: There are those who suspect Wildflower Center volunteers are the culpable and capable culprits. Yet, others think staff members play some, albeit small, role. You can torture us with your plant questions, but we will never reveal the Green Guru's secret identity.
Did you know you can access the Native Plant Information Network with your web-enabled smartphone?
Ask Mr. Smarty Plants is a free service provided by the staff and volunteers at the Lady Bird Johnson Wildflower Center.
rate this answer
Wednesday - July 02, 2014
From: Tacoma, WA
Region: Northwest
Topic: Invasive Plants, Non-Natives, User Comments
Title: Foxglove (Digitalis purpurea)
Answered by: Nan Hampton
QUESTION:Foxglove (digitalis purpurea) is not a native U.S. plant. It was introduced to the U.S. from Europe and is now considered invasive in many parts of the western U.S. It invades our forested wild lands and is beginning to colonize our highway medians. The USDA plant database shows Foxglove is an introduced species. You need to click on their link "View Native Distribution" to see that information. The USDA map that is initially displayed only reports a plant' presence in a state, that does not mean the plant is "native" in a state.
Mr. Smarty Plants wholeheartedly agrees with all your statements above, but is wondering why you have written this to us. Is there somewhere on our webpage that we indicate that the European Digitalis purpurea (Purple foxglove) is a North American native plant?
I searched our Mr. Smarty Plants questions and found six of them that mention Digitalis purpurea (Purple foxglove). In each of those questions (9255, 8606, 8143, 8628, 8579, 8167) we indicate that it is not native. Also, it isn't listed in our Native Plant Database as a native plant. If I have somehow missed it and there is a reference on our webpage that even suggests that Digitalis purpurea is native to North America, please let us know and we will correct it.
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July 21, 2011 - I bought a portulaca in a hanging basket and divided it up and planted it in my garden. It is doing ok..but I have almost entirely orange flowers..maybe two reds. I was hoping for multi-colored..red...
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March 20, 2014 - Still have cabbage weeds that infiltrated Austin awhile back. How did Wildflower Center resolve it?
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March 25, 2014 - What type of clumping bamboo can be grown outdoors in planters in Dallas,TX?
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October 28, 2011 - I have heard that there is a type of herbicide that is to be applied to slashes made in the outer layer of invasive trees such as Paulownia. This type of application is reputed to prevent the little ...
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March 23, 2011 - A week or so ago, I purchased two beautiful pink jasmine vines. The first few days after planting, they did wonderful. Now, some leaves and stems are turning brown and some flowers have fallen off. ...
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[Watch] This is how you Survive in No Man's Sky
Yesterday at 10:45 am | 5 Comments
So over the weekend, the cover box art for Madden NFL 15 emerged. It features Seattle Seahawks' cornerback Richard Sherman -- winner of this year's Madden NFL 15 cover vote -- striking an awkward pose.
While I originally thought Sherman wanted us to "talk to the hand" on the cover, further research revealed that he's actually doing his best "Stop in the Name of Love" impression.
Shortly after winning the fan voting competition, Sherman stated that he preferred the entire "Legion of Boom" join him on the cover of this year's Madden. Maybe it's not too late because this is just plain awkward.
Oh, and in all likelihood Sherman giving us the hand is probably more about showing off the design on his glove.


text:
Thursday, 28 July 2016
Last updated 5 hours ago
Feb 10 2014 | 11:20am ET
The first month of 2014 was highly mixed for the hedge fund industry.
The average hedge fund lost 0.6% in January, according to the HFRI Fund Weighted Composite Index. But that was a much narrower loss than that suffered by the Standard & Poor's 500 Index, which the Hedge Fund Research benchmark trailed badly all of last year.
And while the overall HFRI index lost ground along with most strategies tracked by the suite, a fair number enjoyed gains, especially relative-value funds. Technology and healthcare funds did best in January, rising 1.88%, followed by corporate fixed-income funds at 1.24%, asset-backed funds at 1.18% and convertible arbitrage funds at 1.15%.
Equity-market neutral funds gained 0.72% on the month, yield alternatives funds 0.57%, relative-value funds 0.54%, short-bias funds 0.38%, multi-strategy funds 0.23%, distressed and restructuring funds 0.02% and active-trading macro funds 0.01%.
Emerging markets funds were battered in January, with the HFRI Emerging Markets (Total) Index dropping 2.6%. Latin America funds were hit hard by troubles in Argentina and Brazil, falling 6.15% on the month. Russia and Eastern Europe funds dropped 3.66%, global funds 2.34% and Asia ex-Japan funds 1.12%.
Other losing strategies included energy and basic materials funds, down 2.05%; systematic diversified macro funds, down 1.79%; and macro funds, down 1.13%. Quantitative directional funds were off by 0.77%, equity hedge funds by 0.73%, activist funds by 0.7%, event-driven funds by 0.37%, merger arbitrage funds by 0.14% and discretionary thematic funds by 0.05%.
Funds of hedge funds dropped 0.62% on the month.
"Risk and volatility quickly returned to complacent global financial markets to begin 2014, contributing to and highlighting significant strategic, intra-strategy and exposure-specific categorical performance disparities and correlation deviations," HFR President Kenneth Heinz said. "While beta-oriented emerging markets, equity hedge and quant CTA strategies led declines, fundamentally-based RVA, technology and quantitative equity market neutral posted gains."
Jul 8 2016 | 7:01pm ET
Recent market volatility has investors seeking greater insight into alternative...
Jul 25 2016 | 6:29pm ET
If you are compelled by stories of entrepreneurial vision & drive, or simply...
Jul 22 2016 | 8:44pm ET
When the press reports extraordinarily strong relative or risk-adjusted returns...


text:
Below: The Belle's Car Doom Hula attraction, September 28, 1992, 2:29 p.m.
The Belle's Car Doom Hula line is like a journey through the bad part of Doomtown. The attraction cars are built like Beauty the Cab, and when you drive you can hula them by strangling the steamers.
Beware Zombie Mode
© copyright 2011–2016
A Pants Aflame production


text:
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Fashionable Fitness Gear: Lose Holiday Pounds in Style
With the holiday season over weve added memories in our hearts, clothing to our closets, and, unfortunately, inches to our waists. On average, people gain 7 to 10 pounds during the holiday season, and if youre part of that stat, its time to get your butt back in the gym. Have no fear; you can be stylish while you sweat. Check out our most fashionable fitness gear to wear while shedding those holiday pounds. Work it, girl!
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Jockey sports bras at Kohl's - This women's Jockey wire-free sports bra features removable foam cups, a moisture-wicking fabric bl...end, mesh layer in the back and a seamless design. Style no. 6997. Shop our full selection of women's Jockey apparel at Kohl's. read more
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These plus size capri leggings are a basic that are useful year round. Wear alone or under one of our great tunics no matter how y...ou style these leggings you ll be cool and comfortable. legging silhouette is never too tight, binding or restrictive 18... read more
Hit the gym in style in these women's Phys Ed shorts. Slim fit, all cotton shorts feature a 3'' inseam, a wide elastic waistband w...ith stripe accents, and the school logo printed on the left leg. read more
RBX fade resistant capris feature moisture wicking fabric, a speckled stripe print, and a hidden pocket in the waistband. 21 inch ...inseam. 88% Polyester, 12% Spandex. Machine wash. Tumble dry. read more
This Natalie Bike Short Is Great For Class, Performances, Or Working Out And Can Be Rolled Down In Front For A Trendy Look! 1 Inse...am. Hand Wash In Cold Water. Hang Dry. read more
Find Pants at Target.com! Score essential yoga style with MSC Yoga Leggings. Made of cotton with spandex for stretch, these yoga p...ants are super comfy, stretchy and soft. They have a fold-over waist for a great fit, and they move with you from warm up... read more
RBX offers bold, stylish designs for your active lifestyle. Stretch capris feature a wide elastic waist for comfortable pull-on st...yling., Women > Plus Size Apparel > Activewear read more
43% Polyester, 43% Cotton, 14% Spandex Fabric: NG Yoga pant contrast colored side stripe Pull-on elastic waistband and drawcord Sn...ug fit with a 4-way stretch for freedom of movement Dry wick finish to provide optimum ventilation Hand or machine wash, tumble dry low Inseam: 23 in. Front rise: 8 3/4 in. Back rise: 12 in. read more
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Banded waist, Allover print, Approx. 9 rise, 17 length, Imported
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Old Navy Full panel with elasticized waistband. Smooth, quick drying compression tricot is designed for peak active performance. A...ll over chalk stripe pattern. Flatlock seams prevent chafing; gusseted for ease of movement. Active logo at back waist.... read more
Stylish Gear
If you are looking for a convenient, fun, and easy way to stay in shape, the easyFiT Folding Magnetic 2-in-1 Bike is perfect for y...ou. With the ability to adjust into a wide range of positions, from horizontal to upright, the easyFiT bike gives maximum comfort. Eight magnetic resistance levels give you the ability of taking it easy or going all out. The heart pulse sensor and LCD monitor display allows you to monitor your progress and increase your motivation. You have the ability to track your distance, heart rate, calories burned, speed, and time. Whatever your goal is, you will be sure to be able to reach it. This sturdy bike offers an added level of support with safety straps on the pedals. Able to fit heights ranging from five feet three inches to six feet, the easyFiT bike is great for the family. Space is not an issue either. When you are done, the bike will fold to nearly half its size and has transportation wheels for easy storage. read more
Track your workouts, progress, and sleep patterns with the Polar Loop 2. Shows daily activity, calories burned, steps taken, and s...leep patterns. Provides vibrating inactivity alerts. Waterproof, soft silicone wristband. Compatible with Polar H7 Bluetooth Smart Sensor. Connects to free Polar flow app. read more
Introducing the new Polar M400 GPS Fitness Watch with optional Heart Rate Monitor and built in GPS. The M400 activity tracker brin...gs together style, performance & comfort – with an exceptional blend of a sporty design with advanced training and activity tracking. With the M400 you can easily monitor your speed, pace, distance & monitors heart rate while having real time training guidance and goals. The M400 also tracks 24/7 activity & sleep, providing you with a full view of your day. Incorporating the best of fitness & activity tracking, with true training intelligence you've come to love from Polar. Quick Specs 24/7 activity tracking Activity goal and activity benefit Inactivity alert Sleep duration and quality Built-in GPS Fitness test (heart rate sensor required) Heart rate with Polar H7 heart rate sensor(optional) Personal best rewards after training Training feedback Standard micro USB charging Polar Flow web service and app MyFitnessPal integration (iOS only) Compact GPS Sport Watch with Optional Heart Rate From the Training Experts Please use the drop down menu's to select between the optional heart rate transmitter. Features Training Benefit - Gives feedback of the effect of each training. (Optional HR Transmitter required) Running Index (RI) - Helps to monitor your running performance, both aerobic fitness and running economy. RI score is calculated after every run, based on your heart rate and speed. (Optional HR Transmitter required) Daily Activity - Tracks activity 24/7 and guides how to reach your personal daily activity goal. Helps to understand the benefits from the increased activity and see if your training, daily activity and resting are in balance.å Smart Calories - Smart Calories calculates the number of calories expended in each training and during the day. Target Planning Tool and Polar Training Programs - Easy target setting with Flow's Target Planning Tool. Create targets and sync them into your M400 to guide you through the training, e.g. keep steady pace or phase your training with different intensities. Polar Training Programs help you to improve your performance and train towards your goal, e.g. half marathon. (Optional HR Transmitter required Fitness Test - Follow how your fitness is improving. Test estimates your maximum oxygen uptake. (Optional H7 Heart Rate Monitor Transmitter required) Daily Activity With inbuilt 3D accelerometer - M400 tracks all your activity 24/7 Get you personal daily activity goal and follow progress during the day Goal can be followed from one of the clock faces Get guidance how to reach your goal View daily active time, calories and steps/distance Be notified in case you are inactive too long Activity overview with Flow App Activity goal with guidance for current day Activity benefit for each day Activity intensity levels Total active time Calories Steps/distance Sleep time/index Inactivity alerts Specs Specs Size : Weight 56,6g / Thickness 11,5 mm Display : Sharp high resolution B&W display with plastic window / 128x128 resolution with up to 4 values in training views Integrated GPS : Speed, distance, altitude, route / Faster GPS signal acquisition Activity Sensor : Daily activity / Sleep (Flow App, Flow web service) Laps : Manual laps / Autolaps (time or distance) Audio Alerts Sensors : Bluetooth Smart HR sensors (H7 compatible) Waterproof : WR30 Memory 4MB : 30h training with GPS and HR (depends on the language settings) Rechargeable Battery : 250 mAh Li-pol battery / Up to 9h training time with GPS & sensors, up to 24 days in time mode with daily activity monitoring (tbc) Connectivity : USB cable for data sync with PC or Mac (Connect SW needed) / BT Smart with mobile SW Updateable : New functionalities with free updates or read more
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Monitoring every element of your fitness-fueled lifestyle, the Polar A360 Fitness Tracker is a smart fitness watch with a sleek, e...legant-looking design. The A360's wrist-based heart rate monitor ditches bulky chest monitors and measures your heart rate with flashing LEDs along the underside of the watch, so you're able to exercise at optimal intensity to make the most of every workout. Movement-based metrics provide speed and distance stats when you're walking and running, regardless if you're on the treadmill indoors or jogging through the neighborhood. 24/7 activity tracking counts steps and automatically monitors sleep time and quality. Used with Polar's Flow app, the watch's 24/7 activity tracking supports your daily fitness goals and commitment to better sleep. The Smart Calories function provides an estimate of calories burned, based off your physiological data (weight, height, age, and gender) and is crunched alongside daily activity and heart rate stats. Plus, its waterproof design won't succumb to soaking rains or submersion, so it won't be game over when you get caught out in the rain on your run. Keeping up to date with tech-savvy trends, the A360 connects via Bluetooth with your smartphone, delivering text message updates, incoming calls, and social media notifications directly to your wrist. Smart notifications are incredibly useful for exercising without being tethered directly to your phone. The A360 is compatible with iPhones running iOS7 or later and Android 4. 3 or later smartphones. The included Micro USB cord charges and syncs the A360's data when it's connected to a Mac (OS X10. 6 or later) or PC (Windows XP, 7, 8, or 10). read more
Non-Slip Surface Providing Extra Comfort and Protection During Yoga, Pilates, and Stretching Exercise Routines
Womens Athletic Golf Shoes from New Balance: New Balance NBGW1001 Minimus (Women's) - White. Athletic Cleat . Sizes: 10.5,6,6.5,7,...7.5,8,8.5,9,9.5 Widths: Medium (B). A new kind of golf shoe inspired by the minimalist running shoe trendBreathable, water-resistant mesh upper with welded TPU stability overlaysLace-up closureREVlite cushioning midsole for reduced weightApprox. 4mm heel to toe drop for a natural feel and fitDual-density spikeless rubber sole read more
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Red Lion Heavyweight Wristbands and Headbands. These are heavyweight, plush terry pile.


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sr occupational therapist jobs
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Occupational Therapist
Interim HealthCare - Pueblo, CO
Occupational Therapist Benefits:. Current licensure or certification as an Occupational Therapist in the state of Colorado....
Occupational Therapist / OT
Brookdale - Minneapolis, KS
Successful completion of the National Certification Examination for Registered Occupational Therapist. Bringing new life to senior living....
Occupational Therapist-Home Health, Santa Cruz, CA
Healthy Living At Home, Santa Cruz, CA - Santa Cruz, CA
State Licensed, Joint Commission Accredited, and Medicare Certified Home Health Agency actively recruiting for Occupational Therapists in the Santa Cruz, CA.*....
In Home Occupational Therapist
Outreach Physical and Occupational Therapy and Speech Rehabilitation, PLLC - Manhattan, NY
The Occupational Therapist is responsible for:. Masters degree a minimum for Occupational Therapist (OT)....
Occupational Therapist-Home Health-San Joaquin County
Healthy Living At Home, San Joaquin County area - San Joaquin County, CA
State Licensed, Joint Commission Accredited, and Medicare Certified Home Health Agency actively recruiting for Occupational Therapists in the San Joaquin County...
Occupational Therapist - Full time
Healthy Living at Home - Modesto, CA - Modesto, CA
Healthy Living at Home, is a new State licensed, Joint Commission accredited, home health agency who is actively recruiting Registered Nurses, Licensed...
Occupational Therapist-Home Health
Trinity Management Services Organization - Sacramento, CA
Occupational Therapist License. Healthy Living at Home, Inc. _State Licensed, Joint Commission Accredited, and Medicare Certified Home Health Agency actively...
Kettering Health Network - Dayton, OH
The Staff Occupational Therapist is a skilled professional who provides day-to-day occupational therapy services to patients on the rehab unit....
Occupational Therapist (OT)
Brookdale Healthcare Services - Glendale, CA
The Occupational Therapists responsibilities are:. Brookdale offers our part-time Occupational Therapists (OT):....
Senior Occupational Therapist
The University of Texas Medical Branch - Galveston, TX
Participates in training and supervision of entry-level therapist and mentoring Occupational Therapist. Certified Hand Therapist (CHT) preferred....