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Letter to the Editor 11-22-13
Dear Editor:
I recently learned of some funding administered by the Kansas Department of Transportation, called Safe Routes to School. It apparently pays for, among other things, sidewalk construction! Who knew?
I find this extremely interesting. As I drive 11th Street three or four times each week, about 3:30 every afternoon, I have seen groups of youngsters, mostly boys, walking east in the street because there is no sidewalk! In fact, from the intersection of Highway 81 and 11th Street as far east as one can go, there is no sidewalk!
Numbers of students walking this route is something I've not seen before this fall, probably because fifth and sixth graders are now attending classes in the Junior-Senior High building.
We have a sidewalk from 6th Street south to the Airport Park, and thankfully there are few kids living at the airport park. But there are a lot of kids who do live east of Highway 81 and they cross the highway where there is a traffic light. They have been well taught, they walk on the left side of the street, facing oncoming traffic. They are well behaved and all of them cute, but there is a tremendous amount of traffic going east and west and not a lot of walking room. Of course there is a lot of traffic! The elementary school is located at the far east end of this very same street. Safe Routes to School . . . we need this in Concordia!
Nancy Champlin
Prairie Pondering
Remembering the smoke-filled rooms . . . "The Atlantic" recently ran a lengthy commentary by Jonathan Rauch. It was "How American Politics Went Insane." He got into history with the party bosses, smoke filled rooms, deals made and carried... [More]
Letter to the Editor 7-22-16
Dear Editor, Voting!! As I was lying awake last night, thinking about the day and what Ted Cruz said at the Republican Convention. I realized I had to agree with him. Yes, I agree his timing and choice of place to present his feelings was probably not the best, but... [More]
More Opinions
- Letter to the Editor 7-22-16
- Prairie Pondering
- Letter to the Editor 5-27-16
- Letter to the Editor 5-7-16
- Prairie Pondering
- Letter to the Editor 2-26-16
- In the Mean Time
- Letter to the Editor 2-19-16
Get in the Cloud grants awarded
Four business in Cloud County have been approved to receive Get in the Cloud grant funds. The Cloud County board of commissioners approved Get in the Cloud County grant applications for Moody Hue Studio, Concordia; Old Mill Custom Cabinets, Glasco; Designs 4 U, Concordia; and... [More]
Increasing number of commissioners to appear on ballot
Voters in Cloud County will decide in November if the county board of commissioners will be increased from three members to five members. A petition to increase the number of county commissioners, circulated by Gary Fraser, Concordia, was presented to the County Clerk's Office... [More]
Ribbon cutting ceremony for recently merged banks
A ribbon cutting in Concordia yesterday marked the merger of Peoples Exchange Bank with American State Bank & Trust Company of Great Bend. The two banks are owned by American State Bancshares of Wichita. The merger was effective July 11. James Koch, who currently is... [More]
More News
American Legion drops Osborne to win state title
OSBORNE — Putting up six runs in the top of the fourth inning, the Concordia American Legion knocked off host Osborne 9-3 in the championship game of the Kansas Pee Wee Baseball State Tournament Friday night. The American Legion was clinging to a slim 2-1 lead heading into... [More]
American Legion advances to state title game
OSBORNE — Winning a matchup of two Concordia teams, the American Legion advanced to the championship game of the Kansas State Pee Wee Baseball Tournament. The American Legion shut out 16th Street Car Wash 5-0 in the tournament semifinals on Thursday night. Advancing to... [More]


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Sateen Sunday: Take 15% off 1+ Yards of Organic Cotton Sateen Ultra fabric through 11:59 p.m. EDT July 24th.
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- Audible Audio Edition
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- Publisher: James Somers
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Instead, I will just let you know there are plenty of angels, werewolves, vampires, elves, and yes even zombies. This author has successfully crafted these elements together making an exciting story, and it all fits together well. This story drew me in with its details, its connections to real sites and certain civilizations. At times I was at awe at the daunting premise of this book. It is simply amazing.
Overall, the writing is superb. The sentences flowed well. It does go back and forth between first and third person, but there is a reason why. Also, as a note there is no cursing. So, if you buy the book, keep all of these aspects in mind.
Thank you James Somers for such an exciting read!
If you enjoy fantasy, battles and good verses evil, you will enjoy this story told from the vantage of Brody West, a young man who find himself stranded in London an befriended by angels and others. I'm looking forward to reading Book 2 of the Descendants Trilogy.
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I enjoyed this book very much. This was my first James Somers book and I am looking forward to continuing the series.Published 1 month ago by Kindle Customer
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Had my imagination working overtime! I particularly liked the book biblical references in coordination with the fantasy aspect of the story. On to book 2 immediately.Published 2 months ago by Camara
I loved this book and have just started reading "Descendant," which is book 2 in the series. This book showed me that Christian Sci-fi really exists. Read morePublished 4 months ago by Joy Takala
Was not even remotely what I thought it would be, the writing was all over the place and the storyline would get really good and then awkward things were thrown in. Read morePublished 6 months ago by MeliG
I would consider this a young adult book, but it is a well woven story. I enjoyed reading it.Published 6 months ago by Chel


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Oncology Nurse Practitioner opportunity in Central Illinois.
Sign on and Relocation! Brand new Heart and Vascular Institute!
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...I earned my BA with honors at Emory University in Romance Languages, majoring in Spanish. I spent one year of my university career studying in Madrid, Spain for full academic credit. I earned my MS in Applied Linguistics and Teaching English as a Second Language at Georgia State University with a 4.0 for the degree.
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While you'll continue to find the print editions of The Oracle, Monday through Thursday in yellow boxes on campus, we hope you will also regularly visit our website usforacle.com as we strive to update it as news happens.
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text:
|Publication number
|Publication type
|Application number
|Publication date
|Nov 26, 1985
|Filing date
|Nov 15, 1983
|Priority date
|Nov 15, 1983
|Fee status
|Publication number
|William R. Bronn
|Original Assignee
|Riker Laboratories, Inc.
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (6), Non-Patent Citations (1), Referenced by (5), Classifications (9), Legal Events (5)
|External Links: USPTO, USPTO Assignment, Espacenet
This invention relates to substituted pyridine compounds and a synthetic process which are useful in the preparation of compounds of pharmaceutical interest.
Esters of benzoic acid which are substituted on the aromatic ring by 1,1-dihydroperfluoroalkoxy substituents and exhibit anesthetic activity are described in U.S. Pat. No. 3,655,728. Amides of benzoic acid which are substituted on the aromatic ring by 1,1-dihydroperfluoroalkoxy substituents and exhibit antiarrhythmic activity are described in U.S. Pat. No. 3,719,687. U.S. Pat. Nos. 3,900,481, 4,071,524 and 4,097,481 describe antiarrhythmic agents including, inter alia, N-(piperidylmethyl)benzamides substituted by one or more 1,1-dihydroperfluoroalkoxy groups. Above-mentioned U.S. Pat. No. 3,900,481 discloses the compound 2,5-bis(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)benzamide, a particularly useful antiarrhythmic agent also known as flecainide. An article appearing in the Journal of Medicinal Chemistry, Vol. 20, pg. 821 (1977), discloses many of the compounds of the patents, and also discloses various additional compounds such as 2-(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)benzamides in which the aromatic ring is substituted in the 5-position by a non-functional group, i.e., methyl, chloro or fluoro.
U.S. Pat. No. 4,339,587 discloses 5-hydroxy-2-(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)benzamide and synthetic intermediates useful in the synthesis thereof. This compound is a metabolite of flecainide, and is useful as an intermediate in the synthesis of flecainide and as an antiarrhythmic agent itself.
In one aspect, the present invention relates to compounds of Formula I ##STR1## wherein A is selected from the group consisting of ##STR2## and acid addition salts thereof when A is --CH2 NH2.
In another aspect, the present invention relates to compounds of Formula II ##STR3## wherein Q is selected from the group consisting of --CH2 NH2 and ##STR4## and acid addition salts thereof when Q is --CH2 NH2.
The compounds of Formulas I and II are useful as synthetic intermediates in the preparation of 5-hydroxy-N-(6-oxo-2-piperidylmethyl)-2-(2,2,2-trifluoroethoxy)benzamide (a metabolite of flecainide) and 2,5-bis(2,2,2-trifluoroethoxy)-N-(6-oxo-2-piperidylmethyl)benzamide.
In still another aspect, the present invention relates to a process for preparing 5-hydroxy-N-(6-oxo-2-piperidylmethyl)-2-(2,2,2-trifluoroethoxy)benzamide and 2,5-bis(2,2,2-trifluoroethoxy)-N-(6-oxo-2-piperidylmethyl)benzamide using the above intermediates.
Synthetic 5-hydroxy-N-(6-oxo-2-piperidylmethyl)-2-(2,2,2-trifluoroethoxy)benzamide is useful as a standard for monitoring the metabolism of flecainide in mammals. As for 2,5-bis(2,2,2-trifluoroethoxy)-N-(6-oxo-2-piperidylmethyl)benzamide, it is believed that this compound could be reduced to provide flecainide and that it therefore is a useful synthetic intermediate.
Acid-addition salts of certain of the compounds of Formulas I and II may be prepared by conventional techniques. Typically, such salts are prepared by reacting the respective compound with an equimolar amount of a relatively strong acid, preferably an inorganic acid such as hydrochloric, sulfuric or phosphoric acid in a polar solvent. Isolation of the salt is facilitated by the addition of a solvent in which the salt is insoluble, an example of such a solvent being diethyl ether. Formation of an acid-addition salt may be desirable during purification of the respective compounds.
The following reaction scheme shows the synthetic route by which the compounds of Formulas I and II may be obtained and the manner in which they may be used. In the reaction scheme, B is --CH2 φ or --CH2 CF3 ; and Y is --CH2 CF3 or hydrogen, with the provisos that Y is --CH2 CF3 when B is --CH2 CF3, and Y is hydrogen when B is --CH2 φ. ##STR5##
In step (1) the known compound 2-cyano-6-methoxypyridine (Formula III) is reductively acetylated to provide the novel 2-acetamidomethyl-6-methoxypyridine (Formula IV). The reductive acetylation is carried out catalytically in the presence of hydrogen gas and Raney nickel catalyst. An acetate salt such as sodium acetate is required, preferably in 0.1 to 1.0 molar amounts relative to the compound of Formula III. A large excess of acetic anhydride is used. The reaction occurs readily at moderate (0� to 50� C.) temperatures.
The compound of Formula IV is deacetylated by conventional acid hydrolysis techniques in step (2) to provide novel 2-aminomethyl-6-methoxypyridine (Formula V). It has been found that dilute aqueous hydrochloric acid accomplishes this reaction readily with simple refluxing. The compound is obtained as a hydrochloride addition salt.
In step (3) the 2-aminomethyl-6-methoxypyridine of Formula V is converted to novel 6-aminomethyl-2(1H)-pyridone (Formula VI). This conversion is somewhat slower than the deacetylation of step (2), but it occurs readily also. Indeed, the reaction conditions of step (2), if carried out for several hours, were found to partially achieve the reaction of step (3). Step (3) was completed by heating and refluxing compound of Formula V (or a mixture of IV and V) in 48% hydrobromic acid. The product is obtained as a hydrobromide addition salt.
Step (4) involves the reaction of 6-aminomethyl-2(1H)-pyridone (Formula VI) with 5-benzyloxy-2-(2,2,2-trifluoroethoxy)benzoyl chloride, (Formula VIA), a compound described in U.S. Pat. No. 4,339,587. This reaction can also be carried out between 6-aminomethyl-2(1H)-pyridone and the known compound, 2,5-bis(2,2,2-trifluoroethoxy)benzoyl chloride. This reaction may be carried out in an inert solvent such as acetone with (preferably) or without an acid acceptor such as sodium carbonate.
Compounds of Formula VII wherein B is 2,2,2-trifluoroethyl can be converted directly by catalytic reduction to a novel compound of Formula VIII wherein Y is trifluoroethyl. This reduction is rapidly accomplished as shown in step (5) on a Parr apparatus at about 20� C. using rhodium on alumina (Al2 O3) as catalyst in the presence of hydrogen gas. It is preferred to use a non-reactive solvent such as a lower alkanol, for example, ethanol and/or methanol.
The compound of Formula VII wherein B is benzyl is converted as shown in step (6) to a novel compound of Formula IX by catalytic reduction on a Parr apparatus at about 20� C. The catalyst used is palladium on charcoal. The reduction is carried out in an inert solvent such as a lower alkanol, for example, ethanol and/or methanol.
In step (7), the compound of Formula IX is reduced to provide a compound of Formula VIII wherein Y is hydrogen. This reduction is readily accomplished as shown in the presence of hydrogen gas using rhodium on alumina as catalyst. The reduction occurs rapidly at 20� C. in a nonreactive solvent such as a lower alkanol, for example, ethanol and/or methanol.
The following examples illustrate the preparation of compounds of the invention.
A mixture of 1.0 g (7.46 mmole) of 2-cyano-6-methoxypyridine, 0.37 g (4.48 mmole) of sodium acetate, 25 ml of acetic anhydride and about 1.0 g of Raney nickel was hydrogenated on a Parr apparatus for about 5.5 hours. The mixture was filtered, and then evaporated with warming in vacuo to provide 2-acetamidomethyl-6-methoxypyridine. The structural assignment was supported by infrared spectral analysis.
The crude product, 2-acetamidomethyl-6-methoxypyridine from Example 1, was combined with 10 ml of 6N hydrochloric acid, and the resulting mixture was heated at its reflux temperature for about 16 hours. The mixture was evaporated to provide a tan solid residue. The product was determined by infrared and nuclear magnetic resonance spectral analyses to be a mixture of 2-aminomethyl-6-methoxypyridine hydrochloride and 6-aminomethyl-2(1H)-pyridone hydrochloride.
The crude product from Example 2 was combined with 10 ml of 48% hydrobromic acid, and the resulting mixture was heated at its reflux temperature for one hour. Evaporation to dryness provided 6-aminomethyl-2(1H)-pyridone hydrobromide as a water-soluble solid. The structural assignment was supported by infrared and nuclear magnetic resonance spectral analyses.
To a stirred mixture of the crude product from Example 3, 20 ml of acetone and 4.7 g of sodium carbonate was added dropwise 2.8 g (8.21 mmole) of 5-benzyloxy-2-(2,2,2-trifluoroethoxy)benzoyl chloride in 10 ml of acetone. The mixture was stirred at about 20� C. for about 16 hours. To the mixture was added 50 ml of acetone, and the resulting inorganic residue was separated by filtration and washed with acetone. The filtrate and washings were combined and evaporated. This residue was dissolved in benzene, and the solution was washed sequentially with 10% aqueous sodium carbonate solution, 2% acetic acid, water, saturated aqueous sodium bicarbonate solution and saturated aqueous sodium chloride solution. The organic solution was dried over magnesium sulfate, and then filtered and evaporated. The residue was boiled in carbon tetrachloride, and the mixture was cooled and the solid was separated by filtration. The solid was purified by chromatography on 30 g of silica gel. The column was eluted sequentially with 5% ethyl acetate in dichloromethane and 2% methanol in dichloromethane. The product was obtained as a white solid, 6-[5-benzyloxy-2-(2,2,2-trifluoroethoxy)benzamidomethyl]-2(1H)-pyridone. The structural assignment was supported by infrared and nuclear magnetic resonance spectral analyses.
A mixture of 0.5 g of 6-[5-benzyloxy-2-(2,2,2-trifluoroethoxy)benzamidomethyl]-2(1H)-pyridone, 60 ml of ethanol, 40 ml of methanol and 0.043 g of 10% palladium on charcoal was hydrogenated on a Parr apparatus at about 20� C. for about 16 hours. Filtration followed by evaporation of the filtrate provided a residue which was triturated with acetonitrile. The solid was separated by filtration and washed with acetonitrile to provide 6-[5-hydroxy-2-(2,2,2-trifluoroethoxy)benzamidomethyl]-2(1H)-pyridone. The structural assignment was supported by infrared and nuclear magnetic resonance spectral analyses.
A mixture of 0.16 g (0.468 mmole) of 6-[5-hydroxy-2-(2,2,2-trifluoroethoxy)benzamidomethyl]-2(1H)-pyridone, 0.05 g of 5% rhodium on alumina and 50 ml of methanol was hydrogenated on a Parr apparatus for 50 minutes. The mixture was filtered, the filtrate was evaporated, and the residue was dried to provide 5-hydroxy-N-(6-oxo-2-piperidylmethyl)-2-(2,2,2-trifluoroethoxy)benzamide. The structural assignment was confirmed by comparison of infrared and nuclear magnetic resonance spectra to those of the same compound prepared by an alternative synthetic procedure.
|Cited Patent
|Filing date
|Publication date
|Jul 22, 1970
|Apr 11, 1972
|Riker Laboratories Inc
|N-(2 - dialkylaminoalkylene)-esters of fluoroalkoxy-substituted aryl carboxylic acid and salts thereof
|Jul 22, 1970
|Mar 6, 1973
|Riker Laboratories Inc
|N-(2-dialkylaminoalkylene)amides of 1,1-dihydroperfluoroalkoxy-substituted aryl acids and salts thereof
|Apr 1, 1974
|Aug 19, 1975
|Riker Laboratories Inc
|Derivatives of pyrrolidine and piperidine
|Nov 8, 1976
|Jan 31, 1978
|Riker Laboratories, Inc.
|Derivatives of urea
|Nov 8, 1976
|Jun 27, 1978
|Riker Laboratories, Inc.
|Tertiary amide derivatives of pyrrolidine and piperidine
|Jun 8, 1981
|Jul 13, 1982
|Riker Laboratories, Inc.
|5-Benzyloxy or 5-hydroxy-2-(2,2,2-trifluoroethoxy)-N-(2-pyridylmethyl)benzamide
|Citing Patent
|Filing date
|Publication date
|Feb 3, 1987
|Apr 25, 1989
|Riker Laboratories, Inc.
|Multi-step process for producing 5-hydroxy-N-(6-oxo-piperidyl-methyl)-2-(2,2,2-trifluoro-ethoxy)-benzamide and derivatives
|Apr 29, 2005
|Nov 27, 2008
|Hans-Georg Schwarz
|Azinyl Imidazoazine and Azinyl Carboxamide
|Aug 13, 2008
|Feb 18, 2010
|Bayer Cropscience Ag
|New N-substituted azinylalkyl-azincarboxamide compounds useful e.g. in plant protection, for combating animal pests, arthropods, nematodes and plant diseases, and for protecting industrial materials against attack and destruction by insect
|Feb 11, 2010
|Aug 24, 2011
|Laboratorios Liconsa, S.A.
|Pharmaceutical mini-tablets for sustained release of flecainide acetate
|Dec 29, 2010
|Aug 18, 2011
|Laboratorios Liconsa, S. A.
|Pharmaceutical mini-tablets for sustained release of flecainide acetate
|U.S. Classification
|546/291, 546/300, 546/233
|International Classification
|Cooperative Classification
|European Classification
|Nov 15, 1983
Owner name: RIKER LABORATORIES, INC. A DE CORP.
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:BRONN, WILLIAM R.;REEL/FRAME:004201/0035
Effective date: 19831111
|Feb 13, 1989
|Fee payment
Year of fee payment: 4
|Jun 29, 1993
|Maintenance fee reminder mailed
|Nov 28, 1993
|Lapse for failure to pay maintenance fees
|Feb 8, 1994
|Expired due to failure to pay maintenance fee
Effective date: 19891128


text:
The Alfred Hitchcock Hour TV Show Watchlist
Season 2, Episode 17 The Jar
In this horror tale adapted from a Ray Bradbury short story, a man (Pat Buttram) buys a jar containing a mysterious "thing." Tom: James Best. Clem: Slim Pickens. Gramps: Carl Benton Reid. Thedy: Collin Wilcox. Emmy: Jocelyn Brando.
Guest Cast
Carl Benton Reid Carl Benton Reid Gramps
James Best Tom
Slim Pickens Slim Pickens Clem
Pat Buttram Pat Buttram Charlie Hill
Cast & Details See all »
- Rating: None
- Premise: The classic series switched to an expanded format in 1962 as `The Alfred Hitchcock Hour,' with the twist endings and Hitch's witty introductions intact, and memorable episodes such as the Emmy-winning `The Jar' (written by James Bridges). (more)
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- 1. Rami Malek
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Arizona Cardinals
SI.com's Peter King: Carson Palmer to the Cardinals is 'inevitable'
Over the past week, the Arizona Cardinals have been linked to quarterback Carson Palmer should he be released by the Oakland Raiders.
But according to SI.com's senior NFL writer Peter King, Steve Keim and Co. might not wait for the former Pro Bowler to hit the open market.
In his weekly Monday Morning Quarterback column, King wrote that Arizona would likely have to give Oakland a fourth or fifth-round pick to complete a deal for Palmer, and that it could happen as early as Monday.
Palmer's numbers (8-16 as a starter, 35 touchdowns and 30 interceptions) with the Raiders over the past two seasons weren't reflective of the quarterback he was earlier in his career in Cincinnati, but King seems to believe reports of his demise have been greatly exaggerated.
Let's not be delusional about Palmer. You can't say he's a premier player anymore, but you also can't say he can't play. He threw for 4,018 yards, and his interception percentage (14 picks on 565 attempts, 2.5 percent) was lower than that of Drew Brees and Eli Manning. He wants to play the Arians way. I believe Arians is the best coach in the league for Palmer. I also believe Palmer wouild buy in totally to Arians' plan, and I hear he's excited about a chance in Arizona. A move would allow him to stay close to his southern California home, and to play in a system that wouldn't be a reach for his game. And Palmer would have the kind of reliable deep-threat receiver in Larry Fitzgerald that few quarterbacks have at their disposal.
The Cardinals currently have four quarterbacks (Drew Stanton, Brian Hoyer, John Skelton and Ryan Lindley) under contract, but Palmer would certainly fit the kind of big-armed quarterback Bruce Arians wants to run his offensive system.
Still, King doesn't seem to think the addition of the former Heisman Trophy winner would do much to improve the Cardinals' chances of winning the division next season.
Does that mean Arizona will contend? I doubt it sincerely. The leaky offensive line must be significantly better to give the immobile Palmer a chance to play well. But of all the quarterbacks on the market or in the 2013 draft, Palmer gives the Cardinals the best chance to be competitive as the fourth-best team in a suddenly very good NFC West.
Under his current deal with the Raiders, Palmer is owed $13 million in 2013, however he has previously turned down Oakland's request to take a paycut.
Should a trade between Arizona and Oakland come to fruition, King noted that he doesn't see a new contract being an issue for Palmer, after all who wouldn't welcome the chance to throw passes to Larry Fitzgerald for a living?
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Thanks for clearing that up: Harlem, Georgia's Born Again Independent Baptist Church has a special message for everyone during the holiday season about free speech and two different men in red suits.
Well, he's been modeling for this statue that's (hopefully) gonna be placed next to a Ten Commandments statue on the lawn in front of Oklahoma's state capitol, courtesy of those noted holiday-cheer-spreaders, the Satanic Temple. Vice has hella (sorry) more under-construction pics of the statue, right this way.
Florida Agrees That Satanists Must Have Equal Representation In Capitol
The Satanic Temple scored a free-speech victory in its quest for equal representation among the Florida state capitol building's religious-themed holiday displays.
The Most Convoluted DMCA Takedown Request of All Time
Anti-Gay group Straight Pride UK is abusing the DMCA takedown process to censor work by a journalist. No surprise there—the DMCA is twisted for all kinds of dumb purposes. The inexplicable part? The hate group filed a takedown on... its own press release. How dare you say that we said the words that we wrote in a…
Censored NBC-Slamming Journalist Guy Adams Is Back On Twitter (Updated)
Guy Adams—the journalist banned by Twitter after slamming NBC's Olympics coverage again and again—is back in the game. His Twitter account has been activated again, as this image shows.


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Aircraft parts found in village pond in Beed district
Beed: Parts of a small aircraft which is believed to have crashed 68 years were found in a large pond here in Central Maharashtra.
The aeroplane parts were found in the pond at Rutiiman village under Ashti tehsil of this district during desilting work yesterday, said Sanjay Pawar, the local Tehsildar.
The reservoir, built in around 1938, was a major source of water for the locals. The pond dried up last year due to scanty rainfall and drought-like situation. Hence, the local administration decided to undertake desilting work.
During the work, labourers found a big and 2-3 small parts of what appeared like a plane. The big part looked like the engine of a small aeroplane, may be a two-seater one, Pawar said.
An elderly villager, Raghunath Raut, told visiting mediapersons that they had seen a plane falling into the pond in 1945. There were three eyewitness of to the incident of which Raut is the only one who is alive today.
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Thursday, 28 July 2016
Last updated 1 hour ago
Aug 28 2013 | 11:46am ET
Elena Ranguelova has joined Investcorp's U.S.-based hedge fund business as head of credit and equity strategies.
Ranguelova joins Investcorp from Pioneer Investments, where she was global head of credit and event-driven strategy research. She also served as a member of the board of directors for Pioneer Alternative Investments New York. Earlier, she ran Goldman Sachs' fundamental strategies team in New York. She began her career as a structured credit strategist with Lehman Brothers.
In her new role at Investcorp, Ranguelova will be responsible for supporting the growth of investments in emerging managers and the single manager platform, the firm's hedge fund seeding business.
"Elena has established an exemplary track-record working with credit and equity hedge fund managers throughout her career. Her analytical experience will serve as a great complement to the depth of the Investcorp hedge fund team, and her extensive network on the sell side enhances Investcorp's ability to evaluate new emerging managers," said Savio Tung, CEO, North America, in a statement.
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University of Cambridge > Talks.cam > Category Theory Seminar > Coherence for symmetric monoidal bicategories
Coherence for symmetric monoidal bicategories
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If you have a question about this talk, please contact Julia Goedecke.
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Other listsSpring School 2010 - 'Axon-Glia Biology in Health and Disease' Civil Engineering Talks Camtessential Group
Other talksWhat can gambling machine data tell us about betting behaviour? Controlling Life with Photons Barrier-Aware Warp Scheduling for Throughput Processors Mesembryanthemums Improving techniques and technology for cellular and molecular pathology Lunchtime Talk: Helen's Bedroom


text:
Four Up
By Samantha Anne Carrillo
Whether you're craving a Lou Reed tribute by female Americana musicians, new-school West Coast rap, rediscovered concert compositions or bitchin' Atlantan garage-punk, Four Up has you covered. Now with A/V!
Sonic ReducerPerfect Pussy Say Yes to Love · The Porter Draw The Porter Draw · JoyCut PiecesOfUsWere-LeftOnTheGround
This week we listened to new and forthcoming releases from Perfect Pussy, The Porter Draw and JoyCut. Now with A/V!
EVENT HORIZON (Monday, Aug 1)
Vans Used to be for Skaters, Now They Just Mean You Like to Rock
2016 Vans Warped Tour • Atreyu • Good Charlotte • pop punk • New Found Glory • rock • Mayday Parade • Motionless in White • metal • Waka Flocka Flame • rap
By August March
Good news, everybody! This year's Van's Warped Tour is coming through Burque—albeit the festival's given up its lauded positioning at the big amphitheater south of town for the slightly more placid, arcadian and sometimes floaty atmosphere at Balloon Fiesta Park…
Today's Events
Scotty and the Atomics • rock, reggae, funk at The Palace Restaurant and Saloon
Fallen Prophets • metal • End To End • Ol' Dagger • Sorry Guero! at Launchpad
Alchemie • indie, modern rock at Hotel AndaluzMore Recommended Events ››
Low Life Vids'n'Vinyl • 8.11.2016
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Below: The Suzanna Astro Blasters attraction at park closing
Ride along with Suzanna as she attempts to save a blueprint from the volcanic Emperor Xulr. Your banana is equiped with a laser blaster with which you can blast at amusing targets with the attraction. See if you can get a new native score and send Xulr back to Mexico!
Please don't try Princess Mode
© copyright 2011–2016
A Pants Aflame production


text:
International Internet Magazine. Baltic States news & analytics
Sunday, 24.07.2016, 23:21
Supreme Court orders Kargins and Krasovickis to pay over EUR 2 million to Reverta24.07.2016.
The Supreme Court's Department of Civil Cases today ruled that former Parex Banka owners and board members Valerijs Kargins and Viktors Krasovickis would have to pay more than EUR 2 million to the joint-stock company Reverta, reports LETA.
Keyword tags: Banks, Financial Services, Latvia
24.07.2016.Klaipeda leads Baltic ports by cargo turnover in H1
23.07.2016.Canadian Embassy warns travelers of unauthorized websites offering eTA
23.07.2016.Superbus to discontinue operations in Estonia
23.07.2016.Latvian Constitutional Court opens several cases following complaints about solidarity tax
23.07.2016.Riga Radio and TV Tower included in state protected cultural monuments list
23.07.2016.EU-2020 strategy has shown progress in headline indicators
23.07.2016.Latvia registers EU's 5th largest GDP budget surplus in Q1
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- 20.07.2016Mass migration from eastern Europe has hampered region's growth – IMF note
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- 20.07.2016Economics Ministry proposes energy efficiency fee in Latvia


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Baby born into a bloodbath: President Assad's British-born wife Asma, 37, said to be PREGNANT with her fourth child
- Asma al-Assad, 37, reported to be pregnant by Beirut-based newspaper
- Mother-of-three rarely seen in public, making claims hard to substantiate
- Comes as opposition activists report bodies of at least 65 males executed in a river in Aleppo
Syria's First Lady Asma Al Assad is pregnant according to Beirut-based al-Akhbar newspaper
Syrian President Bashar Al-Assad's British-born wife is pregnant, according to reports.
The dictator is said to have told mysteriously anonymous Arab 'visitors' to Syria, who passed it on to Beirut newspaper al-Akhbar, generally regarded as sympathetic to his regime.
The London-born mother of three, Asma Assad, 37, once described by Vogue magazine as a 'rose in the desert', has not been seen in public in recent months, making the claim hard to substantiate.
Efforts by MailOnline to confirm the report with her father Dr Fawaz Akhras, a Cromwell Hospital and Harley Street cardiologist failed.
The al-Akhbar article focused on Assad's take on the ongoing civil war that has gripped Syria for the last two years and his confidence in his army's ultimate success.
It said: 'On the personal level, the man seems
calm and in control.
'His confidence level stands out. Also there's the
news of the pregnancy of his wife Asma, which could not be dealt with as
a simple personal matter between a couple.'
Though a Muslim, Asma Assad went to a Church of England school, where she was known as Emma.
After studying computer science and French literature at King's College London, she worked as a banker at JP Morgan in the Nineties when she met her future husband.
At the time, Assad was training at a hospital in London to become an eye surgeon.
It is not the first time rumours of the First Lady's pregnancy have circulated.
In November a Syrian news agency called Akhbar Shabab Soriya (Syria Youth News) said she was five months pregnant. Should this be the case the baby would be due in March.
Revelations: Emails show that the First Lady, left, who married Syrian president Bashar al-Assad, right, in 2000, was kept up to date on how the furniture was being laid out in the palace
Earlier this month Assad and his family were reported to be living on a warship guarded by the Russian navy.
The embattled dictator was said to have moved with his family and a select band of aides to the warship off Syria's coast while he travelled by helicopter to Damascus to attend meetings in his presidential palace.
The move was said to have come about after the president lost confidence in his own security detail.
Emails obtained by WikiLeaks and reported in the mainstream media last year revealed that Mrs
Assad, 36, spent £270,000 buying furniture from an exclusive London
store for one of her presidential palaces in 2011 – as Syria was
descending into a bloody civil war.
Her order included five chandeliers costing £8,800 at upmarket furniture store DN Designs in the King's Road, Chelsea, West London.
In September 2011 international condemnation of the Syrian regime grew and sanctions were imposed against the country by the US and the EU, although Mrs Assad was still preoccupied with her furnishings.
The Assads in Paris in 2008. In November a Syrian news agency called Akhbar Shabab Soriya (Syria Youth News) said she was five months pregnant. Should this be the case the baby would be due in March
Hands bound behind them and shot in the head: Merciless executions of 65 people dumped by a river in Aleppo
By Jill Reilly
A horrifying video has been released showing dozens of corpses with their hands tied behind their backs lined up by a river in Syria.
The bodies of at least 65 men and boys, apparently shot
in the head, were found in a district of the
northern Syrian city of Aleppo earlier today.
Blood was seeping from their heads
and some of them appeared to be young, possibly teenagers, dressed
in jeans, shirts and trainers.
A Free Syrian Army captain said that many more bodies were still being dragged from the water.
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text:
I5 Vs I7 Mobile Gaming/Computing Performance
Last response: in Laptop General Discussion
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text:
Twilight movie T-shirts, mugs, tote bags, cards, stickers, and more with black text design that reads "Here Comes the Human!"
Some of the images on our items are from Kathleen's Kollections.com , jersgirl.com, jrett.com, clipartopolis.com, graphicsfactory.com, www.scrappindoodles.com, www.digiscrapkits.com, www.digiwebstudio.com, and raggedyscrappin.com! Please visit their sites and see more of their beautiful work!
Some images are Copyright © Né Metzger ClipartWhimsy.com
Some of the images on our items are Copyright 2001-2003 Hemera Technologies, Inc.,


text:
i sended you the info.
This member has provided no bio about themself...
i sended you the info.
Da hell is going on in the comments section?
What happened to the original Sand of the Death?
Dude, you could make a good messup mod. But with that you said, im afraid that your mod its not going to make it.
You came back in the worst moment, after all the hate with the messup mods, better to not **** it up, or you are having big problems with the community.
It is, this mod is dead.
Oh cool. Thanks for explaning this to me.
Whats up with the "You´re Done" thingy. Can somebody explain it?
No problem ;)
The Rocket Launcher must be a Dardanelles Gun.
Offtopic. For a reason instead of "HLUE" i saw "HUE".
We are giving this troll a lot of attencion, just ignore this mod unti this one gets bannned.
You never learn, right?
Lol dat animation
And what happened to "Hue-Life"?
Try to add some lighting. With light details your maps are going to look a lot better!
Just stop it.
Well, now is definetly dead.
Wait a sec, did you just changed your comment?
Yeah, this is looking cool!
Nevermind, the picture changed.
Nope, i mean the picture that your mod haves as a thumbnail.
How ironic, the thumbnail of the mod it haves a Gordon Freeman with a H.E.V suit.
Pretty cool, seeing my own country on a game makes me have a strange, but good feeling!
I said that in english just to respect the community.
You know the actual made progress of the mod? I mean if this one is for example in 10% progress
"Poor"? Man, i dont know why you feel soo bad about the scientist. They are complete jerks!
Oh i see, you put this one here for your future project with this models.
You know what? This thing is going to be like the other mod that had ferret skins. But beacuse this kind of developers are a kind of lazy. And beacuse the addon section is abandoned. Maybe that is the reason why they put this files in the mod section.


text:
Support System Important for Sauk Rapids Teen
KVSC News Director Chris Duffy interviews a family friend of Jeff Hinkemeyer. In May of 2009, Hinkemeyer was rear-ended by another vehicle as he was waiting to pull in to his apartment complex and was airlifted to a hospital after his car exploded with him inside. Suffering from third degree burns on 90 percent of his body, Hinkemeyer was put in an induced coma. Kim, a friend of the Hinkemeyer family is organizing a spaghetti dinner and silent auction to raise funds for medical expenses. Kim gives us some insight into the type of individual Jeff is and about his struggles since the accident.
Latest News
Detours Will Direct Voters To Sauk Rapids Government Center On Election Day Aug. 9
St. Cloud Tech High School's Varsity Dance Team Volunteers At Local Elementary School
Minn. DNR Is Conducting A Drawdown To Lower The Water Level Of A Sartell Lake
St. Cloud Police To Recognize 33rd Annual National Night Out
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Newsradio Fan Favorites
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- Run Time: 3 hours, 22 minutes
- Video: Color
- Released: September 29, 2009
- Originally Released: 2009
- Label: Sony Pictures
- Encoding: Region 1 (USA & Canada)
- Aspect Ratio: Full Frame - 1.33
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vp finance jobs near Atlanta, GA
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Commercial Finance Manager
CSM Bakery Solutions - Atlanta, GA
MBA in Finance preferred. In conjunction with Director of Finance and Channel VP, provide long term vision for the channel and implement a strategy to achieve...
Analytics and Strategy Lead
UCB S.A. - Atlanta, GA
We have experience in over 15 different industries, including academia, automobile manufacturing, banking, consulting, consumer packaged goods, finance,...
VP Human Resources
First Data - Atlanta, GA
VP Human Resources. First Data's Shared Services organization, which includes the Human Resources, Finance, Legal, Marketing, Communications, Finance, Strategy,...
Corporate Controller
Lucas Group - Atlanta, GA
This role reports to the VP of Finance and is an opportunity to be in a highly visible role. Due to our clients growth, this Controller position is a newly...
VP Sales
First Data - Atlanta, GA
Collaborates with senior leaders across the organization (including finance, legal, sales support, operations) to develop and maintain effective processes for...
Vice President & General Manager
BrightView - Smyrna, GA
Customer Management (partner with Sales VP). Contract Management (partner with Legal & Finance). New Sales (partner with Sales VP). Brighter futures start here....
Events Manager
First Data - Atlanta, GA
First Data's Shared Services organization, which includes the Human Resources, Finance, Legal, Marketing, Communications, Finance, Strategy, Compliance, Legal,...
Business Applications Manager (ERP)
Sterling Talent Solutions - Atlanta, GA
VP Strategic Operations. The Business Application Manager demonstrates strong influence and communications skills to interact successfully and effectively...
VP Finance - Technical Accounting
Synergy Search Group - Atlanta, GA
These duties will require liaising with senior company personnel, including the Corporate Controller, Chief Financial Officer, Senior Finance Officers for the...
Manager, Commercial FP&A - Americas
CP Kelco - Atlanta, GA
The successful candidate will have a Bachelors degree in finance or accounting. O Support preparation and publication of monthly reporting to VP and Executive...


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Welcome to my profile.
Please call me Karasu. I'm married to Itachi Uchiha. I'm also a moderator for the anime and character databases here on Anime-Planet. If you have any questions or concerns, don't hesitate to ask. :)
10,273 total episodes
Change the "Main Male Lead" to "Only Male Present" and we got a best seller!
Sorry to break it to you, but hey, they already defeated me near a decade back during Naruto when the last 70 episodes were filler. Those were some dark times.
Well whadda ya know, same here! Only difference is...I'm playing the hell out of my game which I thought could never have happened. I'll beat it tomorrow on the fourth day playing because 1) it's about 20 hours long and 2) I've been playing it straight after school's been taken care of until bed. I haven't been so immersed in a game for what seems like forever (maybe Atelier Escha)! The battle system is similar to another series I enjoy, except it adds bowling; there are chibi characters which for some inexplicable reason are designs I have always been fond of in video-games (see Mana Khemia, Atelier Iris, etc); I swear what's the cutest romantic scene ever was in this game, and this is not only due to them being chibis (I will remember it always, although I may forget what game it was from because this game is so short lol); and the story is nowhere near generic as I figured it to be. Man, I can't believe I'm about to use this expression, but...what a nice, pleasant surprise Lord of Magna turned out to be.
I don't hate him, I just wish he wasn't created. Dranzer too. Gawd I hate them. Oh wait. I DON'T KNOW ANYMORE.
I could make it into a sitcom titled "How I Met My Not Girlfriend Because That Pickup Line Failed". It will be a classic.
Maybe because Naruto has been in filler hell for what seems like years and I was craving something from it? Naruto Shippuden was back to the main plot for one episode, and guess what? Yep, the fillers are back and they're about Kakashi, Obito, and Rin again. !!! !!!
I didn't know Star Ocean was that high up your list of games to play next. Gamefly just sent me Lord of Magna: Maiden Heaven. There aren't really any new games I wanted right now, so I figured what the heck, I'll try it. I'm looking forward to Lost Dimension next month though.
Kai and I have a long history, but I guess he's more like a rival. My best friend from childhood was obsessed with him and would buy all of the Dranzer beyblades, while Ray was my favorite so I'd get Driger beyblades.
It is now. Sadly, I haven't run into the situation where I could use it. But I'm sure it'll work somehow. And if it doesn't, then that's fine too because the girl needs to understand at least that much humor to catch MY attention.
Borrow? That's what somebody said about my car. I won't be fooled for a 7.5th time!
Yeah! You can even put that on your tombstone! Kinda jealous now...
It was out of my control! The spoilers came out of nowhere! You know how it is: you'll read an article, then your eyes do their wandering trick, and the next thing you know, you're lost in the spoilers with no way back.
I waited for so many seconds, but I knew you'd return! ...Is what I would say if I didn't give up yesterday.
Lol, my captcha had me select which pictures were of food.
Tip: get Crunchy and Netflix. Second Tip: get two more PS3s. Another Tip: trade in your baby for another PS3 (pfft, if they'd let you - heck, they'd probably say, "Woman, please. I'll give you half a PS3 for this...thing." and they may also make you uncomfortable by asking, "However, if you give me your digits, maybe I can add a digit to what we can pay you...eh? Eh?"). Don't get distracted! Just, get it so you can play it, then return to me with good news that both it and I are awesome.
Why didn't you? Everyone was doing it! Except your dad, I guess.
Perhaps I will be interested. Depends on how the anime ends. Honestly, I don't think I can avoid the spoilers. Yesterday I discovered like the entire Naruto cast got randomly married off to one another...no love for Gaara though. =/
Yeah, you're like never on PSN. T_T That makes your PS3 sad. Come on! Have some fun with it! Your Xbox doesn't have to know if you don't say anything... Considering how difficult/time-consuming it is to get achievements in Star Ocean: The Last Hope, you're really better off playing the PS3 "international, slightly-better" version. Thus, this logic translates to you throwing out your Xbox and joining the dark side! Do it, cuz peer pressure and all that.
If I couldn't be bothered to stay up all night or get up early to watch something, I'd record it on VHS. I recorded SO MUCH as a child. I mean, I did it so many times I could go through the many steps it takes on my vcr with my eyes closed! Shows were being recorded daily, nightly, in the past (whoops), in the future, randomly - you name it. It wasn't limited to anime either.
Inb4 the schedule suddenly changes when an episode titled "Naruto's Grandfather! The Stories of an Older Generation!" appears and we get into an infinite loop of past generations, never getting back to the present time. Everything...becomes swallowed by fillers - Obito's true goal (or maybe the Tsukuyomi already happened!) ...I just terrified myself. But hopefully two weeks comes around and BAM!, Naruto is back for ONE episode to wrap EVERYTHING up. It'll be fun to discuss my confusion when/if this happens.


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Chrome Chromebook (beta)
Best-in-class hardware and software, with flashy design that reflects a new generation of the brightest.
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YouTube SnoopaVision (beta)
A revolutionary new way to watch YouTube
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The new fashion range includes an exciting collection of pants abounding with innovative functions. And, boasting an array of unique, contemporary styles that fit just about any lifestyle, these smart wearables are just that… wearable.
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Google Self Driving Bike (dutch)
Geïnspireerd door de techniek achter de self-driving car introduceert Google dit voorjaar in Nederland de zelfrijdende fiets. De introductie gebeurt vanuit Amsterdam, de fietsstad bij uitstek.
(Inspired by the technology behind the self-driving car Google launches this spring in the Netherlands, the self-propelled bicycle. The launch occurs from Amsterdam, cycling city par excellence)
Google Search for your Socks (beta)
We're teaming up with retailers across Australia to launch a new range of Searchable Socks — to organise the world's undergarments and make them universally findable.
Google Cardboard Plastic (beta)
Google Cardboard Plastic combines everything you love about virtual reality headsets with everything you love about reality.
(↬ Google)
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With our new delivery technology, packages will arrive even faster and land anywhere you want them – whether you're at the beach, in the woods, or even on a run.
Duolingo Pillow (beta)
Learn a language overnight. With the Duolingo Pillow, we guarantee language fluency by sunrise.


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Make It Beautiful With Stop Motion Origami
Johnny Miller and Philip Leaman have created a cute and whimsical stop motion animation featuring little origami squares.
It will be featured in the May 2011 iPad issue for Martha Stewart Living.
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TEAMLISTS | #NRL Round 21 teams are in! Get them all here, with lower grades to come throughout the ...
27 hours ago - 1 Likes
The Brisbane Broncos say hooker Barry Berrigan is unlikely to have further surgery on his neck before the upcoming NRL season.
Berrigan has been cleared by team medicos of any damage to the area where two vertebrae were fused during surgery in late 2004. He will visit his spinal surgeon in Brisbane this evening after complaining of pain in the area for the past few weeks.


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These adorable lion Zooties are handcrafted from locally sourced sheep's wool in Kyrgyzstan. They are the perfect natural and environmentally conscious baby shoe. Made for babies up to 12 months. Handmade in Kyrgyzstan Made from 100% felted wool Sized for babies Velcro strap Who made this product? Silk Road Bazaar works with marginalize artisans in Kyrgyzstan. These craftspeople make these felted wool booties by hand using traditional techniques native to their area. Why is it ethical? Zooties are made of natural and eco-friendly materials by artisans whom are paid fair wage to help live a self-sustaining life. Silk Road Bazaar believes in understanding their artist daily workings by living within their communities for extended periods of time. This way Silk Road Bazaar can use education for self-improvement for each individual worker and their community as a whole.
Quirky Bohemian Mama the store! Curated by me - come check it out! Something for everyone - bohemian home decor, clothing, accessories and more!
Yellow & Red Circles African Wax print Toddler Sundress – Wild Dill
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|By Andreas Grabner
Article Rating:
|December 3, 2012 07:30 AM EST
Swarovski - the leading producer of cut crystal in the world - relies on its eCommerce store as much like other companies in the highly competitive eCommerce environment. Swarovski's story is no different from others in this space: They started with "Let's build a website to sell our products online" a couple of years ago and quickly progressed to "We sell to 60 million annual visitors across 23 countries in six languages." There were bumps along the road and they realized that it takes more than just a bunch of servers and tools to keep the site running.
Why APM and why you don't just need a tool
Swarovski relies on Intershop's eCommerce platform and faced several challenges as they rapidly grew. Their challenges required them to apply Application Performance Management (APM) practices to ensure they could fulfill the business requirements to keep pace with customer growth while maintaining an excellent user experience. The most insightful comment I heard was from René Neubacher, Senior eBusiness Technology Consultant at Swarovski: "APM is not just about software. APM is a culture, a mindset and a set of business processes. APM software supports that."
René recently discussed their Journey to APM, what their initial problems were and what requirements they ended up having on APM and the tools they needed to support their APM strategy. By now they reached the next level of maturity by establishing a Performance Center of Excellence. This allows them to tackle application performance proactively throughout the organization instead of putting out fires reactively in production.
This article describes the challenges they faced, the questions that arose and the new generation APM requirements that paved the way forward in their performance journey:
The Challenge!
Swarvoski had traditional system monitoring in place on all their systems across their delivery chain including web servers, application servers, SAP, database servers, external systems and the network. Knowing that each individual component is up and running 99.99% of the time is great but no longer sufficient. How might these individual component outages impact the user experience of their online shoppers? Who is actually responsible for the end user experience and how should you monitor the complete delivery chain and not just the individual components? These and other questions came up when the eCommerce site attracted more customers which was quickly followed by more complaints about their user experience:
APM includes getting a holistic view of the complete delivery chain and requires someone to be responsible for end user experience.
Questions that had no answers
In addition to "Who is responsible in case users complain?" the other questions that needed to be urgently addressed included:
- How often is the service desk called before IT knows that there is a problem?
- How much time is spent in searching for system errors versus building new features?
- Do we have a process to find the root-cause when a customer reports a problem?
- How do we visualize our services from the customer's point of view?
- How much revenue, brand image and productivity are at risk or lost while IT is searching for the problem?
- What to do when someone says "it's slow"?
The Ten Requirements
These unanswered questions triggered the need to move away from traditional system monitoring and develop the requirements for new generation APM and user experience management.
1: Support State-of-the-Art Architecture
Based on their current system architecture it was clear that Swarovski needed an approach that was able to work in their architecture, now and in the future. The rise of more interactive Web 2.0 and mobile applications had to be factored in to allow monitoring end users from many different devices and regardless of whether they used a web application or mobile native application as their access point.
Transactions need to be followed from the browser all the way back to the database. It is important to support distributed transactions. This approach also helps to spot architectural and deployment problems immediately
2: 100% transactions and clicks - No Averages
Based on their experience, Swarovski knew that looking at average values or sampled data would not be helpful when customers complained about bad performance. Responding to a customer complaint with "Our average user has no problem right now - sorry for your inconvenience" is not what you want your helpdesk engineers to use as a standard phrase. Averages or sampling also hides the real problems you have in your system. Check out the blog post Why Averages Suck by Michael Kopp for more detail.
Measuring end user performance of every customer interaction allows for quick identification of regional problems with CDNs, Third Parties or Latency.
Having 100% user interactions and transactions available makes it easy to identify the root cause for individual users
3: Business Visibility
As the business had a growing interest in the success of the eCommerce platform, IT had to demonstrate to the business what it took to fulfill their requirements and how business requirements are impacted by the availability or the lack of investment in the application delivery chain.
Correlating the number of Visits with Performance on incoming Orders illustrates the measurable impact of performance on revenue and what it takes to support business requirements.
4: Impact of 3rd Parties and CDNs
It was important to not only track transactions involving their own Data Center but all user interactions with their web site - even those delivered through CDNs or third parties. All of these interactions make up the user experience and therefore all of it needs to be analyzed.
Seeing the actual load impact of third-party components or content delivered from CDNs enables IT to pinpoint user experience problems that originate outside their own data center.
5: Across the life cycle - supporting collaboration and tearing down silos
The APM initiative was started because Swarovski reacted to problems happening in production. Fixing these problems in production is only the first step. Their ultimate goal is to become pro-active by finding and fixing problems in development or testing-before they spill over into production. Instead of relying on different sets of tools with different capabilities, the requirement is to use one single solution that is designed to be used across the application lifecycle (Developer Workstation, Continuous Integration, Testing, Staging and Production). It will make it easier to share application performance data between lifecycle stages allowing individuals to not only easily look at data from other stages but also compare data to verify impact and behavior of code changes between version updates.
Continuously catching regressions in Development by analyzing unit and performance tests allows application teams to become more proactive.
Pinpointing integration and scalability issues, continuously, in acceptance and load testing makes testing more efficient and prevents problems from reaching production.
6: Down to the source code
In order to speed up problem resolution Swarovski's operations and development teams require as much code-level insight as possible - not only for their own engineers who are extending the Intershop eCommerce Platform but also for Intershop to improve their product. Knowing what part of the application code is not performing well with which input parameters or under which specific load on the system eliminates tedious reproduction of the problem. The requirement is to lower the Mean Time To Repair (MTTR) from as much as several days down to only a couple of hours.
The SAP Connector turned out to have a performance problem. This method-level detailed information was captured without changing any code.
7: Zero/Acceptable overhead
"Who are we kidding? There is nothing like zero overhead especially when you need 100% coverage!" - Just the words from René when you explained that requirement. And he is right: once you start collecting information from a production system you add a certain amount of overhead. A better term for this would be "imperceptible overhead" - overhead that's so small, you don't notice it.
What is the exact number? It depends on your business and your users. The number should be worked out from the impact on the end user experience, rather than additional CPU, memory or network bandwidth required in the data center. Swarovski knew they had to achieve less than 2% overhead on page load times in production, as anything more would have hurt their business; and that's what they achieved.
8: Centralized data collection and administration
Running a distributed eCommerce application that gets potentially extended to additional geographical locations requires an APM system with a centralized data collection and administration option. It is not feasible to collect different types of performance information from different systems, servers or even data centers. It would either require multiple different analysis tools or data transformation to a single format to use it for proper analysis.
Instead of this approach, a single unified APM system was required by Swarovski. Central administration is equally important as they need to eliminate the need to rely on remote IT administrators to make changes to the monitored system, for example, simple tasks such as changing the level of captured data or upgrading to a new version.
By storing and accessing performance data from a single, centralized repository, enables fast and powerful analytic and visualization. For example, system metrics such as CPU utilization can be correlated with end-user response time or database execution time - all displayed on one single dashboard.
9: Auto-Adapting Instrumentation without digging through code
As the majority of the application code is not developed in-house but provided by Intershop, it is mandatory to get insight into the application without doing any manual code changes. The APM system must auto-adapt to changes so that no manual configuration change is necessary when a new version of the application is deployed.
This means Swarovski can focus on making their applications positively contribute to business outcomes; rather than spend time maintaining IT systems.
10: Ability to extend
Their application is an always growing an ever-changing IT environment. Where everything might have been deployed on physical boxes it might be moved to virtualized environments or even into a public cloud environment.
Whatever the extension may be - the APM solution must be able to adapt to these changes and also be extensible to consume new types of data sources, e.g., performance metrics from Amazon Cloud Services or VMware, Cassandra or other Big Data Solutions or even extend to legacy Mainframe applications and then bring these metrics into the centralized data repository and provide new insights into the application's performance.
Extending the application monitoring capabilities to Amazon EC2, Microsoft Windows Azure, a public or private cloud enables the analysis of the performance impact of these virtualized environments on end user experience.
The Solution and the Way Forward
Needless to say that Swarovski took the first step in implementing APM as a new process and mindset in their organization. They are now in the next phase of implementing a Performance Center of Excellence. This allows them moving from Reactive Performance Troubleshooting to Proactive Performance Prevention.
Stay tuned for more blog posts on the Performance Center of Excellence and how you can build one in your own organization. The key message is that it is not about just using a bunch of tools. It is about living and breathing performance throughout the organization. If you are interested in this check out the blogs by Steve Wilson: Proactive vs Reactive: How to prevent problems instead of fixing them faster and Performance in Development is the Chief Cornerstone.
For basic one-to-one voice or video calling solutions, WebRTC has proven to be a very powerful technology. Although WebRTC's core functionality is to provide secure, real-time p2p media streaming, leveraging native platform features and server-side components brings up new communication capabilities for web and native mobile applications, allowing for advanced multi-user use cases such as video broadcasting, conferencing, and media recording.
Jul. 30, 2016 10:45 AM EDT Reads: 1,053
SYS-CON Events announced today that Venafi, the Immune System for the Internet™ and the leading provider of Next Generation Trust Protection, will exhibit at @DevOpsSummit at 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. Venafi is the Immune System for the Internet™ that protects the foundation of all cybersecurity – cryptographic keys and digital certificates – so they can't be misused by bad guys in attacks...
Jul. 30, 2016 10:15 AM EDT Reads: 1,500
ReadyTalk has expanded the capabilities of the FoxDen collaboration platform announced late last year to include FoxDen Connect, an in-room video collaboration experience that launches with a single touch. With FoxDen Connect, users can now not only engage in HD video conferencing between iOS and Android mobile devices or Chrome browsers, but also set up in-person meeting rooms for video interactions. A host's mobile device automatically recognizes the presence of a meeting room via beacon tech...
Jul. 30, 2016 10:00 AM EDT Reads: 502
The cloud market growth today is largely in public clouds. While there is a lot of spend in IT departments in virtualization, these aren't yet translating into a true "cloud" experience within the enterprise. What is stopping the growth of the "private cloud" market? In his general session at 18th Cloud Expo, Nara Rajagopalan, CEO of Accelerite, explored the challenges in deploying, managing, and getting adoption for a private cloud within an enterprise. What are the key differences between wh...
Jul. 30, 2016 10:00 AM EDT Reads: 2,176
It's 2016: buildings are smart, connected and the IoT is fundamentally altering how control and operating systems work and speak to each other. Platforms across the enterprise are networked via inexpensive sensors to collect massive amounts of data for analytics, information management, and insights that can be used to continuously improve operations. In his session at @ThingsExpo, Brian Chemel, Co-Founder and CTO of Digital Lumens, will explore: The benefits sensor-networked systems bring to ...
Jul. 30, 2016 09:15 AM EDT Reads: 1,646
On Dice.com, the number of job postings asking for skill in Amazon Web Services increased 76 percent between June 2015 and June 2016. Salesforce.com saw its own skill mentions increase 37 percent, while DevOps and Cloud rose 35 percent and 28 percent, respectively. Even as they expand their presence in the cloud, companies are also looking for tech professionals who can manage projects, crunch data, and figure out how to make systems run more autonomously. Mentions of 'data science' as a skill ...
Jul. 30, 2016 09:00 AM EDT Reads: 578
Manufacturers are embracing the Industrial Internet the same way consumers are leveraging Fitbits – to improve overall health and wellness. Both can provide consistent measurement, visibility, and suggest performance improvements customized to help reach goals. Fitbit users can view real-time data and make adjustments to increase their activity. In his session at @ThingsExpo, Mark Bernardo Professional Services Leader, Americas, at GE Digital, discussed how leveraging the Industrial Internet a...
Jul. 30, 2016 08:00 AM EDT Reads: 751
Amazon has gradually rolled out parts of its IoT offerings in the last year, but these are just the tip of the iceberg. In addition to optimizing their back-end AWS offerings, Amazon is laying the ground work to be a major force in IoT – especially in the connected home and office. Amazon is extending its reach by building on its dominant Cloud IoT platform, its Dash Button strategy, recently announced Replenishment Services, the Echo/Alexa voice recognition control platform, the 6-7 strategic...
Jul. 30, 2016 07:45 AM EDT Reads: 716
In addition to all the benefits, IoT is also bringing new kind of customer experience challenges - cars that unlock themselves, thermostats turning houses into saunas and baby video monitors broadcasting over the internet. This list can only increase because while IoT services should be intuitive and simple to use, the delivery ecosystem is a myriad of potential problems as IoT explodes complexity. So finding a performance issue is like finding the proverbial needle in the haystack.
Jul. 30, 2016 07:45 AM EDT Reads: 2,398
There will be new vendors providing applications, middleware, and connected devices to support the thriving IoT ecosystem. This essentially means that electronic device manufacturers will also be in the software business. Many will be new to building embedded software or robust software. This creates an increased importance on software quality, particularly within the Industrial Internet of Things where business-critical applications are becoming dependent on products controlled by software. Qua...
Jul. 30, 2016 07:30 AM EDT Reads: 1,688
Big Data, cloud, analytics, contextual information, wearable tech, sensors, mobility, and WebRTC: together, these advances have created a perfect storm of technologies that are disrupting and transforming classic communications models and ecosystems. In his session at @ThingsExpo, Erik Perotti, Senior Manager of New Ventures on Plantronics' Innovation team, provided an overview of this technological shift, including associated business and consumer communications impacts, and opportunities it ...
Jul. 30, 2016 07:30 AM EDT Reads: 484
The 19th International Cloud Expo has announced that its Call for Papers is open. Cloud Expo, to be held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, brings together Cloud Computing, Big Data, Internet of Things, DevOps, Digital Transformation, Microservices and WebRTC to one location. With cloud computing driving a higher percentage of enterprise IT budgets every year, it becomes increasingly important to plant your flag in this fast-expanding business opportuni...
Jul. 30, 2016 05:15 AM EDT Reads: 2,712
IoT is rapidly changing the way enterprises are using data to improve business decision-making. In order to derive business value, organizations must unlock insights from the data gathered and then act on these. In their session at @ThingsExpo, Eric Hoffman, Vice President at EastBanc Technologies, and Peter Shashkin, Head of Development Department at EastBanc Technologies, discussed how one organization leveraged IoT, cloud technology and data analysis to improve customer experiences and effi...
Jul. 30, 2016 04:00 AM EDT Reads: 2,139
The Internet of Things will challenge the status quo of how IT and development organizations operate. Or will it? Certainly the fog layer of IoT requires special insights about data ontology, security and transactional integrity. But the developmental challenges are the same: People, Process and Platform. In his session at @ThingsExpo, Craig Sproule, CEO of Metavine, demonstrated how to move beyond today's coding paradigm and shared the must-have mindsets for removing complexity from the develo...
Jul. 30, 2016 03:00 AM EDT Reads: 1,657
SYS-CON Events announced today that MangoApps will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. MangoApps provides modern company intranets and team collaboration software, allowing workers to stay connected and productive from anywhere in the world and from any device.
Jul. 30, 2016 02:45 AM EDT Reads: 1,497
The IETF draft standard for M2M certificates is a security solution specifically designed for the demanding needs of IoT/M2M applications. In his session at @ThingsExpo, Brian Romansky, VP of Strategic Technology at TrustPoint Innovation, explained how M2M certificates can efficiently enable confidentiality, integrity, and authenticity on highly constrained devices.
Jul. 30, 2016 02:15 AM EDT Reads: 1,196
"delaPlex Software provides software outsourcing services. We have a hybrid model where we have onshore developers and project managers that we can place anywhere in the U.S. or in Europe," explained Manish Sachdeva, CEO at delaPlex Software, in this SYS-CON.tv interview at @ThingsExpo, held June 7-9, 2016, at the Javits Center in New York City, NY.
Jul. 30, 2016 02:00 AM EDT Reads: 1,694
The IoT is changing the way enterprises conduct business. In his session at @ThingsExpo, Eric Hoffman, Vice President at EastBanc Technologies, discussed how businesses can gain an edge over competitors by empowering consumers to take control through IoT. He cited examples such as a Washington, D.C.-based sports club that leveraged IoT and the cloud to develop a comprehensive booking system. He also highlighted how IoT can revitalize and restore outdated business models, making them profitable ...
Jul. 29, 2016 10:15 PM EDT Reads: 2,088
Internet of @ThingsExpo, taking place November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, is co-located with the 19th International Cloud Expo and will feature technical sessions from a rock star conference faculty and the leading industry players in the world and ThingsExpo Silicon Valley Call for Papers is now open.
Jul. 29, 2016 08:00 PM EDT Reads: 2,756
We all know the latest numbers: Gartner, Inc. forecasts that 6.4 billion connected things will be in use worldwide in 2016, up 30 percent from last year, and will reach 20.8 billion by 2020. We're rapidly approaching a data production of 40 zettabytes a day – more than we can every physically store, and exabytes and yottabytes are just around the corner. For many that's a good sign, as data has been proven to equal money – IF it's ingested, integrated, and analyzed fast enough. Without real-ti...
Jul. 29, 2016 07:45 PM EDT Reads: 1,220


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Build up your biceps and triceps with these simple arm exercises from the American Council on Exercise. Learn valuable how-to information and get expert fitness advice that will help you strengthen your arm muscle groups including the biceps, triceps and wrists. We have a wide variety of arm strenghtening exercises from the beginner to advanced level including the dumbbell bench press, triceps kick-backs, bicep curls and more. For full workout routines that feature arm exercises, check out our Workouts section.
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