text:
Metiphis is not good at identifying bears and that will probably cost him later on in life.
hollaback grandma was raised since birth by MMOs and honestly doesn't know anything about the real world or what lives in it.
Metiphis, can't you see? Your images just hypnotize me.
looking.glass.eyes gives bad directions every time.
It's just a little confusing, is all.
The good news is the republican convention is over. The bad news is if I can escape this police car how do I anull a marriage??
Title of this one pretty much says it all. If it's what you're looking for, then uh, look no further
There is literally nothing sexier than eye contact.
A dandy fop dog gets a rhino piss party and ant enema in the Jungle. Weldcome to Hell.
Photoshop Phriday showcases the tremendous image manipulation talents of the Something Awful Forum Goons. Each week they tackle a new theme, parodying movies, video games, comics, history, and anything else you can think of. If you want in on the action, join us on the Something Awful Forums!
Copyright ©2016 Rich "Lowtax" Kyanka & Something Awful LLC.


text:
|By Marketwired .
Article Rating:
|November 15, 2012 09:07 AM EST
ISELIN, NJ -- (Marketwire) -- 11/15/12 -- eG Innovations, the award-winning provider of automated performance management solutions for virtual, cloud and physical IT infrastructures, today announced its third quarter was highlighted by a record number of new customer wins for management of virtual desktops and applications, product innovation and new strategic partnerships. A report by 451 Research said that eG Innovations is gaining momentum in the application performance management space by building on its steady growth with large enterprise customers.
451 Research noted that eG Enterprise is being used by hundreds of enterprise customers today to provide unprecedented performance visibility, automated cross-silo performance correlation and diagnosis, pre-emptive problem alerting and predictive analytics. These unique capabilities enable companies to accelerate performance diagnosis, reduce operational cost, deliver user satisfaction and unlock the potential of virtual, cloud and physical IT environments.
"Customers are anxious to have a solution that addresses the systemic performance challenges inherent in virtualized environments. Often, these challenges prevent customers from achieving the ROI benefits they envisioned when they embarked on virtualization initiatives," said Srinivas Ramanathan, CEO and founder, eG Innovations. "With eG Enterprise V5.6 our customers will achieve even broader value as we deliver total performance visibility across the virtualized IT infrastructure. Going forward, we will build on our success by focusing on further accelerating the discovery, diagnosis and resolution of critical business service performance issues."
Completing Q3, eG Innovations has achieved these significant results:
Accelerating Customer Growth: Today over 400 enterprise customers use eG Innovations' eG Enterprise to manage their dynamic enterprise IT infrastructures, including VDI, application virtualization, and Citrix XenApp / XenDesktop technologies, besides other conventional IT applications like SAP, Java apps, databases, etc.
Strong Product Innovation: eG Enterprise 5.6 builds on automated correlation and problem diagnosis technology to accelerate performance diagnosis, reduce operational cost, deliver user satisfaction and unlock the true potential of virtual, cloud and physical IT environments. The company was awarded two patents recently. The first one relates to its virtualization-aware automatic root-cause diagnosis technology that correlates application and virtualization performance. A second patent focuses on eG Innovations' In-N-Out monitoring technology for virtual infrastructures that provides correlated outside and inside view of virtual machines.
Strategic Partnerships: eG Innovations and Egenera announced a joint solution that offers customers greater return-on-investment by automating provisioning, performance management and capacity planning. With the joint solution, customers benefit from faster problem identification and resolution, thereby freeing up IT operations time for more strategic initiatives.
eG Innovations announced a partnership with Red Hat whereby administrators can use eG Enterprise to monitor the Red Hat Enterprise Virtualization server and desktop platforms -- including the Red Hat Enterprise Virtualization hypervisor, datastores, virtual networks and Virtual Machines. Additionally, eG Innovations' software has been validated by Microsoft to work with Microsoft System Center Operations Manager (SCOM).
Additional resources
To read more about eG Innovations in the 451 Research Report written by Dennis Callaghan and Karin Kelley entitled: "eG Innovations leaves no performance stone unturned in latest release" click here or follow the link: (https://451research.com/report-short?entityId=74087)
Join the eG Innovations live webinar on November 29 @ 2:00 pm ET: "Application Performance Management -- 5 Steps to Performance Assurance for Dynamic IT Environments" with APM expert Dennis Callaghan, senior analyst, Enterprise Software Group, 451 Research. Register here: (https://www1.gotomeeting.com/register/427030417)
About eG Innovations
eG Innovations provides intelligent performance management solutions that dramatically accelerate the discovery, diagnosis, and resolution of service performance issues in virtual, cloud, and physical service infrastructures. Only eG Innovations offers 360-degree service visibility with automated, virtualization-aware performance correlation across every layer and every tier -- from desktops to applications and from network to storage. This unique approach delivers deep, actionable insights into the true causes of cross-domain service performance issues and enables administrators to pre-emptively detect, diagnose and fix root-cause issues -- before end users notice.
eG Innovations' award-winning performance management and monitoring solutions are trusted by the world's most demanding companies to enable delightful user experiences, keep mission-critical business services at peak performance and deliver on the ROI promise of transformational IT investments. Customers include: JP Morgan Chase, Citigroup, Depository Trust and Clearing Corporation, Cathay Bank, AllScripts, Honeywell, Samsung, Xerox, Marathon Oil and many more. Visit http://www.eginnovations.com for more information.
© Copyright 2012. eG Innovations All rights reserved. All trademarks, service marks and company names are the property of their respective owners. All other company, brand and product names may be trademarks or registered trademarks of their respective holders.
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For basic one-to-one voice or video calling solutions, WebRTC has proven to be a very powerful technology. Although WebRTC's core functionality is to provide secure, real-time p2p media streaming, leveraging native platform features and server-side components brings up new communication capabilities for web and native mobile applications, allowing for advanced multi-user use cases such as video broadcasting, conferencing, and media recording.
Jul. 23, 2016 06:45 AM EDT Reads: 557
IoT generates lots of temporal data. But how do you unlock its value? You need to discover patterns that are repeatable in vast quantities of data, understand their meaning, and implement scalable monitoring across multiple data streams in order to monetize the discoveries and insights. Motif discovery and deep learning platforms are emerging to visualize sensor data, to search for patterns and to build application that can monitor real time streams efficiently. In his session at @ThingsExpo, ...
Jul. 23, 2016 06:30 AM EDT Reads: 583
There will be new vendors providing applications, middleware, and connected devices to support the thriving IoT ecosystem. This essentially means that electronic device manufacturers will also be in the software business. Many will be new to building embedded software or robust software. This creates an increased importance on software quality, particularly within the Industrial Internet of Things where business-critical applications are becoming dependent on products controlled by software. Qua...
Jul. 23, 2016 05:15 AM EDT Reads: 1,135
SYS-CON Events has announced today that Roger Strukhoff has been named conference chair of Cloud Expo and @ThingsExpo 2016 Silicon Valley. The 19th Cloud Expo and 6th @ThingsExpo will take place on November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. "The Internet of Things brings trillions of dollars of opportunity to developers and enterprise IT, no matter how you measure it," stated Roger Strukhoff. "More importantly, it leverages the power of devices and the Interne...
Jul. 23, 2016 04:30 AM EDT Reads: 1,911
Machine Learning helps make complex systems more efficient. By applying advanced Machine Learning techniques such as Cognitive Fingerprinting, wind project operators can utilize these tools to learn from collected data, detect regular patterns, and optimize their own operations. In his session at 18th Cloud Expo, Stuart Gillen, Director of Business Development at SparkCognition, discussed how research has demonstrated the value of Machine Learning in delivering next generation analytics to imp...
Jul. 23, 2016 04:00 AM EDT Reads: 2,331
In addition to all the benefits, IoT is also bringing new kind of customer experience challenges - cars that unlock themselves, thermostats turning houses into saunas and baby video monitors broadcasting over the internet. This list can only increase because while IoT services should be intuitive and simple to use, the delivery ecosystem is a myriad of potential problems as IoT explodes complexity. So finding a performance issue is like finding the proverbial needle in the haystack.
Jul. 23, 2016 02:45 AM EDT Reads: 2,049
The Internet of Things will challenge the status quo of how IT and development organizations operate. Or will it? Certainly the fog layer of IoT requires special insights about data ontology, security and transactional integrity. But the developmental challenges are the same: People, Process and Platform. In his session at @ThingsExpo, Craig Sproule, CEO of Metavine, demonstrated how to move beyond today's coding paradigm and shared the must-have mindsets for removing complexity from the develo...
Jul. 23, 2016 01:15 AM EDT Reads: 1,013
SYS-CON Events announced today that MangoApps will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. MangoApps provides modern company intranets and team collaboration software, allowing workers to stay connected and productive from anywhere in the world and from any device.
Jul. 23, 2016 01:00 AM EDT Reads: 1,151
The IETF draft standard for M2M certificates is a security solution specifically designed for the demanding needs of IoT/M2M applications. In his session at @ThingsExpo, Brian Romansky, VP of Strategic Technology at TrustPoint Innovation, explained how M2M certificates can efficiently enable confidentiality, integrity, and authenticity on highly constrained devices.
Jul. 23, 2016 12:45 AM EDT Reads: 719
SYS-CON Events announced today that LeaseWeb USA, a cloud Infrastructure-as-a-Service (IaaS) provider, will exhibit at the 19th International Cloud Expo, which will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. LeaseWeb is one of the world's largest hosting brands. The company helps customers define, develop and deploy IT infrastructure tailored to their exact business needs, by combining various kinds cloud solutions.
Jul. 22, 2016 11:15 PM EDT Reads: 974
Early adopters of IoT viewed it mainly as a different term for machine-to-machine connectivity or M2M. This is understandable since a prerequisite for any IoT solution is the ability to collect and aggregate device data, which is most often presented in a dashboard. The problem is that viewing data in a dashboard requires a human to interpret the results and take manual action, which doesn't scale to the needs of IoT.
Jul. 22, 2016 11:00 PM EDT Reads: 1,790
Internet of @ThingsExpo has announced today that Chris Matthieu has been named tech chair of Internet of @ThingsExpo 2016 Silicon Valley. The 6thInternet of @ThingsExpo will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA.
Jul. 22, 2016 10:45 PM EDT Reads: 1,824
When people aren't talking about VMs and containers, they're talking about serverless architecture. Serverless is about no maintenance. It means you are not worried about low-level infrastructural and operational details. An event-driven serverless platform is a great use case for IoT. In his session at @ThingsExpo, Animesh Singh, an STSM and Lead for IBM Cloud Platform and Infrastructure, will detail how to build a distributed serverless, polyglot, microservices framework using open source tec...
Jul. 22, 2016 10:00 PM EDT Reads: 2,182
"delaPlex Software provides software outsourcing services. We have a hybrid model where we have onshore developers and project managers that we can place anywhere in the U.S. or in Europe," explained Manish Sachdeva, CEO at delaPlex Software, in this SYS-CON.tv interview at @ThingsExpo, held June 7-9, 2016, at the Javits Center in New York City, NY.
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"My role is working with customers, helping them go through this digital transformation. I spend a lot of time talking to banks, big industries, manufacturers working through how they are integrating and transforming their IT platforms and moving them forward," explained William Morrish, General Manager Product Sales at Interoute, in this SYS-CON.tv interview at 18th Cloud Expo, held June 7-9, 2016, at the Javits Center in New York City, NY.
Jul. 22, 2016 09:30 PM EDT Reads: 1,985
A critical component of any IoT project is what to do with all the data being generated. This data needs to be captured, processed, structured, and stored in a way to facilitate different kinds of queries. Traditional data warehouse and analytical systems are mature technologies that can be used to handle certain kinds of queries, but they are not always well suited to many problems, particularly when there is a need for real-time insights.
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The 19th International Cloud Expo has announced that its Call for Papers is open. Cloud Expo, to be held November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA, brings together Cloud Computing, Big Data, Internet of Things, DevOps, Digital Transformation, Microservices and WebRTC to one location. With cloud computing driving a higher percentage of enterprise IT budgets every year, it becomes increasingly important to plant your flag in this fast-expanding business opportuni...
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IoT is rapidly changing the way enterprises are using data to improve business decision-making. In order to derive business value, organizations must unlock insights from the data gathered and then act on these. In their session at @ThingsExpo, Eric Hoffman, Vice President at EastBanc Technologies, and Peter Shashkin, Head of Development Department at EastBanc Technologies, discussed how one organization leveraged IoT, cloud technology and data analysis to improve customer experiences and effi...
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The Internet of Things will challenge the status quo of how IT and development organizations operate. Or will it? Certainly the fog layer of IoT requires special insights about data ontology, security and transactional integrity. But the developmental challenges are the same: People, Process and Platform and how we integrate our thinking to solve complicated problems. In his session at 19th Cloud Expo, Craig Sproule, CEO of Metavine, will demonstrate how to move beyond today's coding paradigm ...
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Big Data engines are powering a lot of service businesses right now. Data is collected from users from wearable technologies, web behaviors, purchase behavior as well as several arbitrary data points we'd never think of. The demand for faster and bigger engines to crunch and serve up the data to services is growing exponentially. You see a LOT of correlation between "Cloud" and "Big Data" but on Big Data and "Hybrid," where hybrid hosting is the sanest approach to the Big Data Infrastructure pro...
Jul. 22, 2016 08:15 PM EDT Reads: 1,739

subset: commoncrawl


text:
B.Sc., North Dakota State University, 1974
M.Sc., University of Virginia, 1976
Ph.D., Engineering Physics, University of Virginia, 1980
Mechanical Aerospace and Nuclear Engineering
J. W. Beams Laboratory of Physics
Room 106 Mc Cormick Road
University of Virginia
Charlottesville, VA 22901
Research Interests
Our research centers on the development of magnetic stereotaxis and medical magnetic manipulation systems for use in neurosurgical, neuroradiological, and other clinical applications. Magnetic stereotaxis is a technique for using magnetic fields and gradients outside the patient's head as a means of navigating an implanted device such as a drug delivery catheter or an intracerebrovascular probe for thrombosing aneurysms. An important part of this effort is the design and prototyping of novel neurosurgical instruments and technologies used in conjunction with magnetic stereotaxis or in related surgical procedures. Other research includes studies of spinal mechanics and the kinematics of the suboccipital region of the craniomandibular complex, the development of stem cell-based techniques for the treatment of Parkinson's disease, and the development of antisense gene therapy strategies for neoplastic diseases of the central nervous system.
Recent Publications
Safayi S, Miller JW, Wilson S, Shivapour SK, Oelfke TF, Ford AL, Klarmann Staudt A, Abode-Iyamah K, Reddy CG, Jeffery ND, Fredericks DC, Gillies GT, Howard Iii MA
Treadmill measures of ambulation rates in ovine models of spinal cord injury and neuropathic pain.
Reddy CG, Dalm BD, Flouty OE, Gillies GT, Howard MA, Brennan TJ
Comparison of Conventional and Kilohertz Frequency Epidural Stimulation in Patients Undergoing Trialing for Spinal Cord Stimulation: Clinical Considerations.
Safayi S, Jeffery ND, Shivapour SK, Zamanighomi M, Zylstra TJ, Bratsch-Prince J, Wilson S, Reddy CG, Fredericks DC, Gillies GT, Howard MA
Kinematic analysis of the gait of adult sheep during treadmill locomotion: Parameter values, allowable total error, and potential for use in evaluating spinal cord injury.
Hack BJ, Ramon SG, Hagen ZA, Theran ME, Burkhardt JD, Gillies GT
Direct vision in minimally invasive epicardial procedures: preliminary tests of prototype instrumentation.
Gillies GT, Unnikrishnan CS
The attracting masses in measurements of G: an overview of physical characteristics and performance.
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text:
At least two hotels on the coast of Maine are offering discounts for the loonie. Here is a peek at Kennebunkport and East Boothbay. Scenic seaside: Ocean Point Inn & Resort is the quintessential Maine getaway, perched on a picturesque point of land on a rocky shore of the Atlantic. It is a vintage landmark resort, […]
La Galerie B&B is a quick and easy country escape from a hot summer in the city. The water of the Richelieu River laps up against the lawn, crickets chirp and birds sing. La Galerie is an ivy-draped red brick manor house built circa 1850, with a fancy wraparound latticework porch shaded by weeping willows, tall oaks […]
Loonie accepted at par for some rafting deals offered by Northern Outdoors Adventure Resort, which has options for experienced rafters and first-timers
The four-day festival returns to the resort for a fourth year, with creative and active pursuits scheduled for Aug. 11 to 14.
One-stop, morning-until-night family-friendly resort, has children's recreation, golf, waterfront dining, beach shops, tennis centre and live entertainment
The five-star urban resort is connected to the Casino du Lac-Leamy and is the match of glitzy Vegas and Atlantic City hotels.
If its nearly 200-year-old stone walls could talk, The British would dish about royalty, politicians and musicians. The British is a darling boutique hotel that opened in May in the historic Aylmer sector of Gatineau. It is the new hot spot along Aylmer's rue Principale, popping with energy and style after a laborious, five-year restoration of […]
The Hollywood, Fla., resort lives up to Jimmy Buffett's philosophy.
Low budget or high budget: Here's how to go slopeside
Boutique hotel has 12 luxurious accommodations, avant-garde artworks and epicurean dining and wining, all on an outstanding Atlantic Ocean beachfront
The boutique chain's latest property features a dazzling lobby and expanded options for food and drink.
Village by the Sea and other properties offer discounts to prop up our lagging loonie.
The 140-room hotel mixes business and pleasure, with a passageway that connects to Centrexpo Cogeco convention centre
Here are some of the best loonie-friendly deals deals offered by hotels and country inns to Canadians at all prices ranges
June 17 to 19 festival celebrates rich, sea-centric history of Kennebunk, Kennebunkport and Arundel
The tableau of a peaceful country getaway is complete at B and B run by Martin Ménard and Man Li
The Upper Town centrepiece's antique charm has been preserved in an $8-million top-to-bottom transformation.
Dominique Truchon, one of the most prominent chefs in the terroir-rich region of Charlevoix, now is an innkeeper as well. Chez Truchon is a wildly popular fine-dining restaurant known for rich and flavourful French-Quebec cuisine made with local ingredients and served fireside in charming surroundings. The inn's latest attraction is its accommodations – the nine […]
Are you travelling overseas but don't want to be out of touch with those back home while in the air? Well Air Canada has a solution for you. The airline announced Monday that it will offer satellite connectivity on international flights. Air Canada already offered Wi-Fi on its flights across North America. "Air Canada […]
The captivating vacation town of Naples, on Florida's Gulf of Mexico coast, is popping with accessible dollar deals for Canadians. On the list below, only the Naples Grande Beach Resort is beachfront on the Gulf of Mexico. The others are in "downtown" Naples, aka Old Naples, an appealing, walkable district of 50 boutiques and galleries […]


text: Home Topics A to Z Wedding Recipes Wedding Recipes A royal occasion requires a royal menu. Celebrate with these wedding recipes and ideas for your special day. Email Browse Recipes and Ideas 121-130 of 159 Results Scallop Ceviche with Melon, Chili, and Mint Recipe courtesy of Tyler Florence Macadamia Coconut Cookie Bars Recipe courtesy of Rachael Ray Chicken Poppyseed Salad Video | (02:44) Chicken Poppyseed Salad makes scrumptious sandwiches for any occasion. Brie with Strawberries on Brioche Crostini Recipe courtesy of Robert Irvine with Brian O'Reilly Potato Chips with Creme Fraiche and Caviar Recipe courtesy of David Tutera Emeril's Hawaiian-Style Poke Recipe courtesy of Emeril Lagasse Lemon Buttercups Courtesy Gale Gand, "Butter Sugar Flour Eggs" by Gale Gand, Rick Tramonto, Julia Moskin, Clarkson N. Potter Publishers, 1999 Chocolate Dipped Strawberries Recipe courtesy of Jill Davie Genoise with Buttercream-Italian Meringue Recipe courtesy of Stanton Ho, Las Vegas, NV Roasted Stuffed Pork Loin with Sweet Potato Puree, Radicchio, and a Molasses Gastrique Recipe courtesy of Jill Davie Previous 1 2 ... 11 12 13 14 15 16 Next


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Independent Living Communities near Phoenix, Arizona
Caring.com offers a free service to help families find senior care. We have thousands of reviews for Independent Living including 80 reviews for Phoenix Independent Living providers. Please explore the information on this page to get contact information and learn about options, amenities, and events.
Olive Grove Assisted Living and Memor...
Phoenix, AZ 85016
Beatitudes Campus
Phoenix, AZ 85021
Madison Meadows
Phoenix, AZ 85020
The Stratford
Phoenix, AZ 85021
Avista Senior Living North Mountain
Phoenix, AZ 85020
Mountain Park Senior Living
Phoenix, AZ 85044
Paradise Village Senior Living
Phoenix, AZ 85028
Phoenix Manor
Phoenix, AZ 85009
The Palazzo
Phoenix, AZ 85015
Fellowship Square of Phoenix, a Chris...
Phoenix, AZ 85029
Paradise Valley
Phoenix, AZ 85028
Liv Ahwatukee
Phoenix, AZ 85048
Brookdale Central Paradise Valley
Phoenix, AZ 85032
LifeStream Complete Senior Living at ...
Phoenix, AZ 85024
Scottsdale Village Square
Scottsdale, AZ 85257
The Springs of Scottsdale
Scottsdale, AZ 85251
McDowell Village
Scottsdale, AZ 85257
Bella Vista Retirement Living
Mesa, AZ 85202
Oasis At Mesa Palms
Mesa, AZ 85201
Avista Senior Living Historic Downtow...
Mesa, AZ 85201
Grand Court Mesa
Mesa, AZ 85201
Casa Del Rio
Peoria, AZ 85381
Atria Chandler Villas
Chandler, AZ 85224
Vista del Rio
Peoria, AZ 85381
The Woodmark at Sun City
Sun City, AZ 85373
The Groves, A Merrill Gardens Community
Goodyear, AZ 85395
More Information About Independent Living
Dreamy Senior Living: Retirement Options You Never Imagined
Article: Senior living options are changing -- and some of the options available are downright dreamy. Don't put off your senior living planning. Get inspired by continuing care communities and independent living options.
Nursing Home, Assisted Living, or Independent Living?
Article: Compare senior housing options such as assisted living, nursing homes, and independent living to see which one's best for your loved one's needs.
The Dangers of Loneliness
Article: Research shows that loneliness can be deadly. Here, 6 tips to help you buffer the negative effects of loneliness.
Senior Living Nearby
Business owner? Claim Caring.com Listing


text:
|Publication number
|Publication type
|Application number
|PCT number
|Publication date
|Sep 6, 2011
|Filing date
|Sep 26, 2006
|Priority date
|Sep 26, 2006
|Fee status
|Also published as
|Publication number
|Alexander G. VILLER, Andrey Buryakov
|Original Assignee
|Viller Alexander G, Andrey Buryakov
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (6), Classifications (14), Legal Events (1)
|External Links: USPTO, USPTO Assignment, Espacenet
This application is a U.S. National Phase of PCT/RU2006/000496, filed on Sep. 26, 2006, the entire contents of which are hereby incorporated by reference.
The invention relates to medicine, namely to methods of endovascular drug therapy, and, in particular, to methods of locally increasing a concentration of drugs in the walls of arteries and veins, in particular for prevention of coronary restenosis.
A number of drugs require intravenous or intra-arterial infusion, by passing the digestive system, so as to preserve the drugs from degradation by catalytic enzymes in the digestive tract. Also, application of a drug with high toxicity in high concentration requires accurate control of their delivery. Moreover, a delivery agent, not being an active pharmacological agent, can still boost the activity of the delivered drug by mediation of its therapeutic activity.
At present, the role of a delivery agent is usually played by a stent with a drug coating. The active substance (paclitaxel, sirolimus, zotarolimus) is dissolved in the polymeric coating of the stent, and is then gradually released, preventing proliferation of smooth muscle cells of an arterial wall, thus preventing evolution and occurrence of restenosis of the stented arteries. At the same time, the drug eluting stents induce an inflammation and can even result in subsequent thrombosis owing to secondary hypersensitivity in some patients, and also owing to a slowdown of endothelization process (see N. Malik et al., "Phosphorylcholine-coated stents in porcine coronary arteries: in vivo assessment of biocompatibility," J Invasive Cardiol. 13 (2001), pp. 193-201, A. V. Finn et al., "Differential response of delayed healing and persistent inflammation at sites of overlapping sirolimus- or paclitaxel-eluting stents," Circulation 112 (2005), pp. 270-278, R. Virmani et al., "Localized hypersensitivity and late coronary thrombosis secondary to a sirolimus-eluting stent: should we be cautious?" Circulation 109 (2004), pp. 701-705). The polymeric coating extends the stage of thrombogenesis and of acute inflammation. All existing intravascular stents used in a clinical practice, have paramagnetic properties, except for diamagnetic nitinol self-expandable stents.
There are alternate ideas of a drug delivery to a vascular wall, in particular, by using composite super-paramagnetic nanoparticles, the ferromagnetic or paramagnetic stents and an exterior magnetic field. At the same time, some data are available about negative biological effects on humans of the impact of a permanent magnetic field with the intensity over 1 Tesla (see Y. Kinouchi, "Electromagnetic Mechanisms of Biomagnetic Effects," The Journal of the Japanese Society of Magnetic Applications in Dentistry, (1997) Vol. 6, No. 1, pp. 13-17). Several comprehensive reviews have attempted to postulate human exposure limits and recommends a level of 0.02 T for continuous exposure. The apparent basis for the 0.02 T recommendation derives from the fact that lowest exposure level which no effect was reported was 0.008-0.01 T (see E. E. Ketchen et al., "The Biological Effects of Magnetic Fields on Man," Am. Ind. Hyg. Assoc. J., 39:1-11 (1978) and Z. N. Nakhilnitskaya, "Biological Effects of Permanent Magnetic Fields," Space Biology and Aerospace Medicine, 8(6): 1-25 (1974)). Two general types of effects from exposures to magnetic fields are postulated as a result of theoretical calculations: magnetomechanical and electromagnetic. Magnetomechanical forces could produce translation and rotation of particles (molecules, cells, etc.), and electromagnetic forces could produce induced voltages and flow modification.
A magnet-controlled system of the targeted drug delivery to destination places, associated with magneto-sensitive particles (see U.S. Patent Publication No. 2006/0041182), where an intravascular magnetized device (for example, a stent made of a paramagnetic material) is implanted, in advance, by a catheter, in the area of interest of the blood vessel, then a polymeric magneto-sensitive carrying agent prepared in the form of particles containing a drug, is injected into the blood vessel, and thereafter, a magnetic field from an exterior source is activated, whereby a gradient magnetic field is generated in the area of interest of the blood vessel, attracting particles of the magneto-sensitive carrying agent.
However, this method cannot be used in organs and vessels with an intensive blood flow. In particular, the aorta and coronary arteries of heart have such high parameters of volumetric velocity of a blood flow, that particles of the carrying agent with size range 0.01 to 1.0 microns will only concentrate in the field of interest in case of the magnetic field induction in excess of 1.0 Tesla. This is unpredictable for the cardiac electrophysiology, for functioning of pace-makers of heart rhythm and carries a risk generating life-threatening arrhythmias. Also, the unpredictable Theological effects caused by concentration of erythrocytes are possible in the area in question. For the particles containing drug with size range 2 to 10 microns, i.e., comparable to size of the blood cell components, concentration on magnetosensitive implants under the force of an exterior magnetic field can result in magneto-induced thrombogenesis. Also, a strong exterior permanent magnetic field has an impact on the central nervous system.
A conventional method of use of a ring catheter (see U.S. Pat. Nos. 5,951,566 and 5,851,218), intended for slow expansion of walls at vasoconstriction without blocking a fluid stream and/or the drainage of sediments on the walls of blood vessels, is known. The method consists of an introduction of a catheter with a conductor of a magnetic field and an inductance coil, and delivery to the area of interest, along with the catheter, of a stent coated with activatable adhesives and provided with elements containing permanent magnets. Interacting of magnetic fields of the inductance coil and of the permanent magnets allows to expand the stent and to intensify the process of implantation of adhesive specimens in the walls of the blood vessel. However, in such an arrangement, the magnetized micro-carrying agents will be attracted to an element with the maximum magnetic intensity, i.e., to the catheter and its components (to the coil core and/or to the ring permanent magnet), instead of the stent on walls of the blood vessel. Thus, it will not be possible to use these micro-carrying agents for intensification of treating the walls of the blood vessel with the drugs. This known method is inapplicable to processing intravascular areas with magneto-sensitive carrying agents containing a drug.
The claimed invention is intended to eliminate the above drawbacks.
The technical result, achieved by application of the claimed method, consists in increased reliability, efficiency and safety of delivery of drugs to a vascular wall and adjoining tissues in the vessels with an intensive stream of blood in the area of implantation of the stent, both at the time of stent implantation, and at a substantially later time, and in particular, in coronary arteries.
Still another technical result of the claimed method consists in lowering the risk of restenosis of arteries in the area of the implanted stent owing to more effective drug administration.
Also, the proposed method is aimed at controlling concentration of the drugs in a vascular wall by means of adjustment of the magnetic field parameters.
The proposed method includes that, for endovascular delivery of a drug in a vascular wall and adjoining tissues in the area of implantation of a stent with paramagnetic properties, a polymeric magneto-responsive carrying agent in the form of particles, containing a drug, is injected. At this moment, a gradient permanent magnetic field is generated and adjusted by means of at least one temporary catheter containing at its distal end, a permanent magnet and/or a solenoid with the core, connected to an electric power source, where the temporary catheter is introduced into the right auricle, and/or into ventricles of heart, and/or into a coronary sinus and/or into a coronary vein, and the maximal gradient of the magnetic induction density is located in the stented arterial segment, thus providing improved settling and deduction of magnetosensitive particles to the inner wall of the blood vessel in the area of the paramagnetic stent implantation.
It is preferable to use, for efficient control of the magnetic field gradient, a solenoid with a core of cylindrical shape, covered by a conical cap, or a permanent magnet of the same shape.
The level of the magnetic induction density of the volumetric gradient magnetic field is adjusted by varying the electric current parameters in the solenoid or by selection of proper permanent magnets.
The effective aiming of the magnetic gradient is implemented by controlled positioning of the inner magnetic sources regarding the stent. Shaping of a three-dimensional permanent gradient magnetic field is also possible.
The stent is made of a paramagnetic material, such as commonly used paramagnetic alloys: steel 316L, cobalt-chromium alloy, cobalt-nickel alloy, etc. Application of biodegradable stents with paramagnetic properties is also possible.
The size of particles of a polymeric magneto-responsive carrying agent is, preferably within the range 0.01 to 1.0 micron.
At the distal end of the temporary catheter, a cylindrical permanent magnet with the typical length range 1 to 50 mm is used.
At the distal end of the temporary catheter, a cylindrical solenoid with the length range 1 to 50 mm can be used, as another alternative.
For better understanding of the claimed invention, its detailed description with corresponding drawings follows.
The claimed method is carried out as follows:
Before stent implantation, the catheter (not shown in the figures) is introduced in that area of the vascular wall which is assigned for the local drug treatment affecting, the catheter carries an intravascular mesh implant, i.e., stent 4 made of a paramagnetic material, for example—steel 316L or other alloys, in particular, cobalt-chromium alloys, cobalt-nickel alloys, and other materials with paramagnetic properties, and also composite materials. Practically any of stents commonly used in a clinical practice can be used in this method.
After installation of stent 4 the catheter is removed, and, through the right atrium and coronary sinus 7, at least one temporary catheter 3 with the permanent magnet or the solenoid affixed at its distal end is introduced in coronary vein 6 and/or in right ventricle 8. The role of such permanent magnet is played by a cylindrical or conical piece of iron, cobalt, nickel, or their alloys, rare earth, magnetic ceramics or polymers filled with particles of the above materials. It is preferable to use the neodymium permanent magnets (NdBFe). In another alternative, the distal end of catheter 3 can carry a solenoid with a core, connected to electric power source 2. The core also can have a shape of a cylinder or can be provided with a conical cap, and the intensity of the gradient magnetic field is controlled by adjustment of the electrical current in the solenoid.
Thus, an endovascular source of a gradient permanent magnetic field, temporarily located in cardiac chambers or/and in the cardiac veins, is created, thereby distance h2 between the source and stent 4 made of magneto-responsive material is substantially reduced and, accordingly, distance between the source and the intravascular area of drug treatment. Experiments confirmed that the optimal alternative consists in designing the distal end of the temporary catheter in the shape of a cylindrical permanent magnet or a solenoid with length range of 1 to 50 mm, thereby achieving an essential decrease (reduction) of working magnetic field intensity to the safety level for a patient.
The distance between the distal end of the temporary catheter and the intravascular stent can thus be reduced to 1 mm. Furthermore, the magnetization of the intravascular stent is maintained only during presence of the gradient permanent magnetic field with the induction level not exceeding 1 Tesla. By means of the controlled current source, it is possible to control the parameters of the magnetic field induced by a solenoid in the area of local drug administering, and, accordingly, to control the level of adhesion of drugs to a vascular wall in the area of implantation of the paramagnetic stent.
At the final stage of the method a magneto-responsive polymeric carrying agent, i.e., the suspension of particles whose size is, preferably, within the range 0.1-1.0 micron, containing a drug, is injected into a vascular channel. Under the force of a gradient permanent magnetic field, the magneto-responsive polymeric particles are concentrated in the area of the stent, thus rendering the targeted drug treatment of the arterial wall, as shown in
Having thus described a preferred embodiment, it should be apparent to those skilled in the art that certain advantages of the described method and apparatus have been achieved. It should also be appreciated that various modifications, adaptations, and alternative embodiments thereof may be made within the scope and spirit of the present invention. The invention is further defined by the following claims.
|Cited Patent
|Filing date
|Publication date
|Jun 11, 1997
|Jul 13, 1999
|Light Sciences Limited Partnership
|Internal magnetic device to enhance drug therapy
|May 2, 2003
|Sep 5, 2006
|Boston Scientific Scimed, Inc.
|Energetically-controlled delivery of biologically active material from an implanted medical device
|Mar 26, 2001
|Nov 29, 2001
|Stanley Satz
|Radioactivatable composition and implantable medical devices formed therefrom
|Aug 22, 2005
|Feb 23, 2006
|Forbes Zachary G
|Magnetically-controllable delivery system for therapeutic agents
|Title not available
|Title not available
|U.S. Classification
|International Classification
|Cooperative Classification
|European Classification


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LANHAM, Md. (CBSDC) — Despite the ongoing controversy surrounding its team name, the Washington Redskins are more valuable than ever.
In Forbes' annual list of the NFL's most valuable teams, Washington is ranked third in the league at $2.4 billion. Only the Dallas Cowboys (1st; $3.2 billion) and New England Patriots (2nd; $2.6 billion) are worth more than the Redskins, according to Forbes.
Dan Snyder's team brought in $395 million in revenue in 2013 and had an operating income of $143 million.
Forbes valued the Redskins at $1.7 billion in last year's rankings.
The Redskins' NFC East New York Giants are worth $2.1 billion — good enough for fourth in the NFL.
The Baltimore Ravens also ranked in the league's top 10 at $1.6 billion. The team made $304 million in revenue in 2013 and had an operating income of $57 million.
"The Ravens inked a 10-year extension to its stadium naming rights sponsorship with M&T Bank in May worth $60 million and will run through the 2027 season," Forbes says.
The average NFL team is currently worth $1.43 billion, the highest value in the 17 years Forbes says it has tracked professional football team finances.
"The $1.43 billion average is 23 percent more than a year ago, the biggest year-over-year increase since 1999," Forbes says.
Redskins News And Rumors
- Colt McCoy Sends Gift of Coffee, Donuts to Police in Texas
- Redskins WR Josh Doctson not Concerned About Achilles Injury — Yet
- Josh Norman Ranked Top Cornerback in Madden NFL 17
- McVay: 'We've Got a Chance to Win Every Game' with Cousins


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P. O. Box 6603 Lincoln, NE 68506 June 20, 2013
President Barack Obama The White House 1600 Pennsylvania Ave NW Washington, D.C. 20500 Mr. Rex W. Tillerson Exxon Mobil Corporation 5959 Las Colinas Blvd. Irving, Texas 75039 Re: Citizens of York, Nebraska Heat Up Dear President Obama and Mr. Tillerson,
This photo was taken at the Bold Nebraska Pipeline Fighter meeting in York this evening (posted on Bold Nebraska's Facebook page with the caption: "Citizens organizing to press their local elected officials to pass county resolutions against Keystone XL." One comment: I still don't understand why you haven't fought the hundreds of other pipelines including the first Keystone XL pipeline. I also don't understand why you are not following up on the hundreds of pipelines that have been decommissioned poorly with much of their infrastructure left in place rusting with who knows what in them. That is much more invasive than a new well maintained pipeline. I replied: I think that all pipelines need to be decommissioned and refineries need to be retired and dismantled, but you gotta start with one ... one highly visible and most symbolic pipeline and refinery. Shut down one refinery and there is no need for Keystone XL. Join me in my http://TellRex.com campaign AND kill Keystone or another piece of the infrastructure. Start with just one. Barack and Rex: Which of you will be Charles Grant?
I challenge the both of you to share the honor. We must quickly begin to abandon fossil fuels You must take bold, courageous action It's time you create your legacy Reduce the infrastructure Retire the refineries
All we want is . . . Clean energy! Carbon-free! Carbon fee Rebate to me Retire the refineries
cc: Secretary John F. Kerry
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Translation of "keep to sth" - English-Traditional Chinese dictionary
(Translation of "keep to sth phrasal verb, verb (SUBJECT)" from the Cambridge English-Chinese (Traditional) Dictionary © Cambridge University Press)
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the activity of knitting something, or a thing that is being knitted


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On Hallowe'en patrol with the police
6.22pm Monday 2nd November 2009
THE County Gazette went on Hallowe'en patrol with the police
Hallowe'en high spirits in Taunton
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Reverend Timothy MacDonald - to part-time Chaplain of Father Luke M. Powers High School, Flint.
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Santa Claus Is Coming To Town Christmas Ornament
Personalized Christmas Ornament
Dimensions: 4" diameter
Material: Glass Ball
This brightly colored blue glass ball is painted in red on the back the words SANTA CLAUS IS COMING TO TOWN. On the front you can see Santa's sleigh completely full with his sack full of toys for good little girls and boys and Rudolph with his bright shiny red nose harnessed up to guide that sleigh through the wintery night. There are added snowflake decorations around the image for an added touch. This makes a great gift for a child that you want to remind Santa is watching to see if he or she makes the Nice List this year and doesn't end up on the Naughty List. A personalized Santa and Rudolph ornament is a great gift for a holiday open house or hostess gift too!
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11/15/2015 - "Have been an OrnamentShop customer for years snd have always been highly satisfied with every aspect. Betty H."
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Thoughts And Prayers With Santa Monica This Weekend
Gunfire broke out late Friday morning as an armed man shot and killed four people in Santa Monica, lighting a house on fire with two of his deceased victims inside before fleeing to the nearby Santa Monica College campus and dying in a police shootout.
President Obama was attending a private Democratic fund raiser not far from the scene, though there is no current word on whether or not the shooting was related in any way. The New York Times has an aggregation of reportage from various sources here, as well as a detailed account here.
Our hearts go out to the victims and their families — stay safe, Santa Monica. We'll be thinking of you this weekend.
Image: Via The New York Times.
- Los Angeles | Santa Monica Gunman Shooting Fire Pictures
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Closed no date set for reopening maybe 2013 when the race track down the road opens
Next year
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Portland Days Inn hotels
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- Most bookedDays Inn Portland/Gresham
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"Good hotel for an overnight stay for people visiting Portland."
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"I didn't expect much based on the reviews, but was well worth it. Our room was remodeled, it smelled clean. Very friendly staff. The downside was that it's too close to the freeway, were light sleepers so it was disturbing. "
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"Hotel seemed to be going through some renovations so was pretty messy"
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"My stay there was a pleasant one staff was great it was well lit for security vehicles"
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"We cannot take stairs so we asked for a first floor room. We got it and made the stay much more pleasant. Got to make waffles. Fun and delicious."
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"We attended a function at PIR across the freeway from the hotel. It was convenient to the location of the show and close enough to walk to and from. We chose to stay, even though the website alerted us to ongoing construction in the hotel. due to the renovations, the hotel was not as clean as it ..."
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The love stories collection 2017
The debut collection from Poppy Dover is themed around iconographies of love with delicately embroidered cupid arrows, love hearts, curling roses, love notes, butterflies and swallows
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Crystal Breeze has been designing and manufacturing occasion wear gowns for over two decades, and the new 2017 collection features new fabrics and shades for every taste
Linzi Jay bridesmaid designs
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Podcast: Talking with Hawkeyes' Fran McCaffery
Iowa's fourth-year head coach takes his team overseas this summer
Mar 28, 2014 at 4:44 pm | Print View
Hawkeyes' men's basketball head man Fran McCaffery joined me to talk about his roots in basketball, his team's upcoming trip to play six games in Europe and the overall state of his program.Below is the full audio of the interview in the newest episode of "The Mike Hlas Podcast." You can subscribe to my podcast on iTunes by clicking here and Stitcher Radio by clicking here.
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Mapping hydrocarbon-induced mineralogical alteration in the northern Tian Shan using ASTER multispectral data
Version of Record online: 8 JUN 2007
DOI: 10.1111/j.1365-3121.2007.00739.x
Terra Nova
Volume 19, Issue 4, pages 225–231, August 2007
Additional Information
How to Cite
Fu, B., Zheng, G., Ninomiya, Y., Wang, C. and Sun, G. (2007), Mapping hydrocarbon-induced mineralogical alteration in the northern Tian Shan using ASTER multispectral data. Terra Nova, 19: 225–231. doi: 10.1111/j.1365-3121.2007.00739.x
Publication History
- Issue online: 8 JUN 2007
- Version of Record online: 8 JUN 2007
- Received 21 October 2006; revised version accepted 24 March 2007
- Abstract
- Article
- References
- Cited By
Seepage from hydrocarbon reservoirs can cause a number of chemical and/or mineralogical changes in overlying rocks and soils. These surface changes can be detected by remote sensing imaging systems. The Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) is an advanced multispectral imaging system in the visible and near infrared (VNIR) to shortwave infrared (SWIR) region. Band ratios of ASTER VNIR and SWIR data to detect red bed bleaching and secondary carbonate formation induced by hydrocarbon seepage are proposed through analysis of the spectral properties of rock samples. Results show that ASTER band ratios of 2/1 and 4/8 can discriminate bleached red beds and secondary carbonate minerals due to hydrocarbon seepage in the northern Tian Shan. They are in good agreement with mineral identification using X-ray diffraction. The ratio technique derived from ASTER data may provide a potential approach for hydrocarbon exploration in areas with sparse vegetation cover.


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ISAF World Cup- Gold and Bronze for New Zealand crews
by Jodie Bakewell-White on 27 Apr 2013
Josh Junior (NZL) - Finn class racing at the ISAF Sailing World Cup Hyeres 2013 Thom Touw ©
Alex Maloney and Molly Meech from New Zealand have won gold at ISAF Sailing World Cup Hyeres in the 49erFX class securing the victory today after six days of racing off the French coast. And Josh Junior has taken his first podium finish at a World Cup Regatta with bronze in the Finn.
'We're definitely happy that we won our first World Cup event in Europe,' says Alex Maloney.
Starting the day with a lead of 18 points the young kiwis were mindful that the changing nature of medal race day meant that anything could happen. In the 49erFX class only the top eight placed crews get to take part in the last day of the regatta, sailing three quick-fire ten minute races on a short 'stadium course' with narrow boundaries. Each of the three races carry double points weighting and poor results on day six can unravel a leading margin very quickly.
'It was tough, it was quite stressful out there,' says Maloney talking about today's racing. 'With it being so light and shifty the leaders changed all the time.'
But Alex Maloney and Molly Meech didn't falter at the final hurdle, staying out of trouble and producing a two fifths and a fourth on the race track today which well and truly secured them the victory. The silver medal winners Charlotte Dobson and Mary Rook representing Great Britain finished 14 points behind the kiwis, with Annemiek Bekering and Claire Blom of the Netherlands collecting the bronze.
Hyeres is the final regatta of the 2012-13 ISAF Sailing World Cup Series and this result secures Maloney and Meech the overall series victory in the 49erFX counting Gold in Melbourne, Silver in Palma and now Gold in Hyeres.
The women's skiff is new to the Olympic programme for Rio 2016, and while Maloney and Meech have proven they're the crew to watch, they know there is lot of water yet to pass under the bridge; 'It's just the beginning, most of the girls are really new in the boat so we've all got a long way to go,' says Molly Meech. 'And it's just going to keep getting harder I guess.'
The girls were supported at this regatta, and also at the last round of the ISAF Sailing World Cup by coach Nathan Handley, who was the man behind Jo Aleh and Polly Powrie's Olympic gold medal winning campaign.
For 23 year old Josh Junior who represents Wellington's Worser Bay Boating Club, a bronze medal in the Finn class is a career highlight to date.
Lying fourth heading out today Junior had nothing to lose and all to gain managing to put together two great medal races placing third, then fourth. It was enough to see him get past Postma (NED) on the leader-board and stand on the podium.
'I've had a really good week, there doesn't seem to be much that's gone wrong,' says Junior at the end of the day. 'I've just kept consistent and kept knocking off good results, and then had two good medal races today and managed to finish on the podium, so I'm stoked!'
Sailing in only his second ever medal race stage in the Finn Josh Junior was able to draw on the experience of team-mate Andrew Murdoch (who finished 12th overall) to prepare himself.
'Andrew Murdoch was out there helping me. We talked a little bit about what might happen, and what we were looking for, and then we set a game plan and went for it,' Junior says.
A further three kiwis were in action in today's medal races also returning top eight results for New Zealand in the Laser, 49er and Men's 470 events.
Andy Maloney sailed well on the final day in the Lasers; with a second and a fifth he has finished this regatta in seventh overall.
After a disappointing opening day in the 49er class kiwis Marcus Hansen and Josh Porebski improved throughout the six days of the event making huge gains to wrap things up in seventh place.
And in the Men's 470 Paul Snow-Hansen and Daniel Willcox come away with an eighth overall with more medal race experience under their belt and plenty of positives to build on from here.
Many of the team now return to New Zealand for a break before the next international event on their calendars.
ISAF Sailing World Cup Hyeres, 2013 - New Zealand's Final Results
1st Alexandra Maloney and Molly Meech
3rd Josh Junior
13th Andrew Murdoch (NZL Sailing Team)
7th Marcus Hansen and Josh Porebski - 49er (NZL Sailing Team) (19, 17, 5, 1, 7, 7, 13, 22, 16, 1)
7th Andy Maloney (NZL Sailing Team)
12th Sam Meech (NZL Sailing Team)
23rd Thomas Saunders
50th Andrew McKenzie (2013 NZL Yachting Trust Youth Team)
91st Michael Cate
107th Jack Collinson
8th Paul Snow-Hansen and Dan Willcox (NZL Sailing Team)
31st Francisco Lardies and Luke Stevenson
12th Gemma Jones and Jason Saunders
20th Tomer Simhony and Nicole van der Velden
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Grave sculpture stolen
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Widower Robin Davies is devastated and appalled after the theft of a treasured sculpture from his late wife's grave.
He noticed the piece missing from its usual position next to the headstone at the North Shore Memorial Park cemetery in Albany on February 16.
He says the bullrush flower sculpture, made from galvanised steel and heavy natural stone, was put there after he bought it in 2009 - one year after his wife died.
"My wife was always a very keen gardener which is why I thought it a particularly appropriate piece to place by her memorial."
Mr Davies immediately reported the theft to staff at the cemetery office who have promised to keep a look out in case it has been thrown into bush on the property, rather than stolen.
"The cemetery is an open access place, but is not specifically policed for grave-robbers," he says.
"I'm sure most people would assume that grave-robbing was a thing of the past - obviously not on the North Shore."
No complaints have been made to police, there is no security camera footage and no witnesses have come forward.
"I spend quite a lot of time at the grave site, going there for chats with my wife and particularly to calm myself down at times when my loneliness and sadness overcome me."
Mr Davies says that he will always be reminded of the theft when he visits.
"I will always be conscious of the fact that it has been stolen by some useless scumbag and probably sold via a car-boot sale."
- North Shore Times
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Today, I placed an order at a fast food joint, when the elderly lady behind me cussed me out for ordering the same thing she wanted. She ranted that I was a "dirty thief", while everyone else glared at me as if I was holding up the line. What the fuck? FML
by dirtythief / 07/18/2013 at 12:01pm / Philippines (Batangas) / Miscellaneous
Today, I finally started exercising. I'm a rather obese person and I'm super pumped up to finally get off my lazy butt and lose some weight. Locking myself in my room, I first started with a very simple exercise: jumping jacks. I farted each time I jumped. I jumped 10 times. FML
by thatonesilentkidinclass / 05/04/2013 at 4:11am / Philippines (Batangas) / Health
Today, I joined a small disaster relief group. I remarked to the big, long-haired person beside me that it was surprising that I was the only female in the group. I got a cold stare. Later I asked another volunteer about that person. He answered, "Oh, her? She's my sister." FML
by Blurry / 09/30/2009 at 3:30pm / Philippines (Batangas) / Work
Today, I was sitting in my garden and having a cup of tea while watching some dragonflies. I thought the dragonflies were really pretty, so I ran towards them and tried to catch their tails like I used to when I was a kid. They were exotic wasps. Ouch. FML
by Lala / 09/10/2009 at 9:40am / Philippines (Batangas) / Animals
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Valentine's Hearts 2006
Valentine's Day cake created for my Mom at work. (She runs an Assisted Living Center.) The bottom layer is french vanilla and the top layer is strawberry, it is iced completely in cream cheese flavored buttercream.
Comments (11)
tyty on
Just beautiful, you did a great job.
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