text:
|By Marketwired .
Article Rating:
|January 9, 2014 06:15 PM EST
SCOTTSDALE, AZ -- (Marketwired) -- 01/09/14 -- In addition to the preliminary fourth quarter results released previously today by Meritage Homes Corporation (NYSE: MTH) in connection with its previously announced equity offering, management further commented that fourth quarter 2013 margins are expected to show substantial improvement over the prior year. Management expects to report fourth quarter 2013 home closing gross margin increased by 400-425 basis points over the fourth quarter of 2012. The Company expects to report its full fourth quarter and fiscal year results on February 5, 2014.
About Meritage Homes Corporation
Meritage Homes is the ninth-largest public homebuilder in the United States, based on homes closed in 2012. Meritage builds and sells single-family homes for first-time, move-up, luxury and active adult buyers across the Western, Southern and Southeastern United States. As of September 30, 2013, the company had 179 actively selling communities in markets including Sacramento, San Francisco's East Bay, the Central Valley and Orange County, California; Houston, Dallas-Ft. Worth, Austin and San Antonio, Texas; Phoenix/Scottsdale, Green Valley and Tucson, Arizona; Denver, Colorado; Orlando and Tampa, Florida; Raleigh and Charlotte, North Carolina; York County, South Carolina and Nashville, Tennessee.
Meritage has designed and built more than 80,000 homes in its 28-year history, and has a reputation for its distinctive style, quality construction, and positive customer experience. Meritage is the industry leader in energy efficient homebuilding and in 2013 Meritage received the U.S. Environmental Protection Agency's ENERGY STAR Partner of the Year for Sustained Excellence Award, for its innovation and industry leadership in energy efficient homebuilding. Meritage was the first national homebuilder to be 100 percent ENERGY STAR® qualified in every home it builds, and far exceeds ENERGY STAR standards today.
For more information, visit meritagehomes.com.
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements include those regarding the Company's expected improvement in fourth quarter home closing gross margin, which are subject to significant risks and uncertainties. Actual results may differ from those set forth in the forward-looking statements. The Company makes no commitment, and disclaims any duty, to update or revise any forward-looking statements to reflect future events or changes in these expectations.
Meritage's business is subject to a number of risks and uncertainties. As a result of those risks and uncertainties, the Company's stock and note prices may fluctuate dramatically. The risks and uncertainties include but are not limited to the following: weakness in the homebuilding market resulting from an unexpected setback in the current economic recovery; the availability of finished lots and undeveloped land; interest rates and changes in the availability and pricing of residential mortgages; the availability and cost of materials and labor; adverse changes in tax laws that benefit our homebuyers; the ability of our potential buyers to sell their existing homes; cancellation rates and home prices in our markets; inflation in the cost of materials used to construct homes; the adverse effect of slower order absorption rates; potential write-downs or write-offs of assets, including pre-acquisition costs and deposits; our potential exposure to natural disasters; competition; the adverse impacts of cancellations resulting from small deposits relating to our sales contracts; construction defect and home warranty claims; our success in prevailing on contested tax positions; our ability to preserve our deferred tax assets and use them within the statutory time limits; delays and risks associated with land development; our ability to obtain performance bonds in connection with our development work; the liquidity of our joint ventures and the ability of our joint venture partners to meet their obligations to us and the joint venture; the loss of key personnel; changes in or our failure to comply with laws and regulations; our lack of geographic diversification; fluctuations in quarterly operating results; our financial leverage and level of indebtedness; our ability to take certain actions because of restrictions contained in the indentures for our senior notes and our ability to raise additional capital when and if needed; our credit ratings; successful integration of future acquisitions; government regulations and legislative or other initiatives that seek to restrain growth or new housing construction or similar measures; acts of war; the replication of our "Green" technologies by our competitors; our exposure to information technology failures and security breaches; and other factors identified in documents filed by the company with the Securities and Exchange Commission, including those set forth in our Form 10-K for the year ended December 31, 2012 under the caption "Risk Factors," which can be found on our website.
Meritage Homes Corporation has filed a registration statement (including a prospectus and a preliminary prospectus supplement) with the SEC for the offering to which this communication relates. Before you invest, you should read the prospectus (including the preliminary prospectus supplement) in that registration statement and other documents Meritage Homes Corporation has filed with the SEC for more complete information about Meritage Homes Corporation and the offering. You may get these documents for free by visiting EDGAR on the SEC web site at www.sec.gov. Alternatively, copies of the prospectus and preliminary prospectus supplement relating to the offering may be obtained from your sales representative: Citigroup Global Markets Inc., fax: (212) 816-7912; J.P. Morgan Securities LLC, 383 Madison Avenue, New York, New York 10179 (fax: (212) 622-8358; Deutsche Bank Securities Inc., Fax (212) 797-9344; or BofA Merrill Lynch at (866) 500-5408.
Brent Anderson
VP Investor Relations
(972) 580-6360 (office)
[email protected]
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Suncoast Chapter 2016 Leukemia Cup Regatta
We invite you to join us this year as we set sail to cure blood cancers!
St. Petersburg Yacht Club Leukemia Cup Regatta
featuring the Ted Irwin Memorial Trophy
October 7-8, 2016
Register for the SPYC Leukemia Cup Ted Irwin Memorial Fall Bay Race
Suncoast Chapter 2016 Leukemia Cup Regatta
Register for an online fundraising page
Not a sailor?... Not a problem! Register as a "Phantom Sailor" to help fund the fight against blood cancers. Every dollar raised is a dollar closer to cures.
Purchase Tickets
Sponsor the Event
Purchase a ticket to our "Spirit of the Sea" Gala Dinner & Silent Auction, Wing Shooter's Clay Shoot Event, or Spectator Boat Ticket.
Make a donation to a SPYC Leukemia Cup participant
A Sailing Fundraiser
Gary Jobson, National Chairman
Since 1993, participants in The Leukemia Cup Regatta events throughout the country have raised over $54 million in funding for The Leukemia & Lymphoma Society to invest in research to find cures for blood cancers - leukemia, lymphoma and myeloma - and to help improve the lives of patients and families. ESPN commentator and 1976 America's Cup winner Gary Jobson, who is a lymphoma survivor, has chaired The Leukemia Cup campaign since its inception.
The Leukemia Cup is a fundraising Regatta and is for everyone that wants to help find a cure for blood cancers. We would love to have you on our team! Phantom Sailors qualify for all the same great benefits as their on-the-water counterparts.
When you fundraise for the Leukemia Cup Regatta, you're participating in the most important race of all...the race to find cures for blood cancers!
Sailors of all levels, including those interested in our new cruising class and those new to the sport of sailing, can participate in the Leukemia Cup. Our Honorary Skippersand local blood cancer survivors will inspire you and remind you of the LLS mission as you join forces to raise vital funds to support our quest for a cure. Contact Brandy Kovarsky at 813-261-3166 or email@example.com today to start fundraising in support of our Honorary Skippers and qualify for exciting incentive prizes!
Interseted in becoming involved with the 2016 SPYC Leukemia Cup Ted Irwin Memorial Fall Bay Race?
Contact Brandy Kovarsky, Campaign Specialist, at 813-261-3166

subset: commoncrawl


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My father is having difficulty breathing... This has happened before when my son received his synagis... SInce he has MS (low immune system) i want to know if this could be the reason...
If my child recieves synagis will it affect my father who has ms?
- Posted:
- 20 Mar 2012 by jordansmom
- Topics:
- synagis, multiple sclerosis
Answers (1)
Jordan didnt have RSV he just recd the syniges shot... It just seemed weird that my father had problems breathing after Jordan came home
Further Information
- Synagis Information for Consumers
- Synagis Information for Healthcare Professionals (includes dosage details)
- Side Effects of Synagis (detailed)
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- 'American Idiot' at EPAC
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- 'Hello, Dolly!' opens Thursday at EPAC
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What's cooking?Student taste buds decide
By: MICHELLE REIFF Review Staff firstname.lastname@example.com, Staff Writer
Last year's taste-testing of school menu options went so well that Cocalico School District decided to once again let students help choose next year's menu at the Student Council Food Show.
About 125 eager students were provided with an array of new items to try as plates with small samples were set up in the high school cafeteria May 17, complete with a score sheet given to each student to rate the products.
This year's assortment included pork barbecue, corn dogs and a new breakfast option — snack waffles. As requested by students, some Asian choices, teriyaki chicken and tangerine chicken, were available this time along with two new wraps — vegetable and Southwestern, adding some healthy alternatives.
Chris Dunn, director of food service for Cocalico, said he's continuing his goal of offering students as much variety as he can while trying to incorporate healthy choices.
"We're introducing as many whole grains as the manufacturers bring in," said Dunn, who is more than pleased that companies are beginning to make foods that are healthy and still taste good. "Without sodium, things taste flat. They are out at food shows testing and then go back to reformulate, which costs them millions."
In light of trying to open the students' minds, pierogies with a broccoli cheese sauce offered for sampling were actually whole grain. Even though the students were unaware of this while trying them, most preferred the other choices.
The Asian options received mixed reviews, the majority of students liked the corn dogs, waffles and the wraps were a bit hit.
"This event is great for all age levels because all the kids are going to say exactly what they think," said high school senior Erin Hess. "There were a lot of interesting things … surprisingly all delicious."
Riggin Dvarishkis, a Denver Elementary fourth grader, proved that even picky eaters were able to find something they enjoyed.
"There are a lot of things I don't like, but I like the tangerine chicken," he raved. "It just tastes good!"
"I don't usually eat food from many different countries," admitted Lilly Boronow, a second-grader from Reamstown Elementary. "I came here last year, but today they had a lot of new foods."
Boronow said that while the corn dogs and waffles were still her favorite, she also enjoyed the Asian choices.
Kassie Nichols, a Shoeneck fourth grade student, said she liked the waffles "cause they were sweet."
The scores will be tallied, and since the students are anxiously awaiting the results, Dunn plans to let them know which choices will make next year's menu before school ends for the summer. More FOOD, page A11
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Welcome to Holy Spirit Catholic School
Holy Spirit Catholic School (HSCS) resides within the family of Elk Island Catholic Schools (EICS) and is part of Alberta's publicly-funded education system. Holy Spirit Catholic School is an elementary/middle school, providing 21st century, quality Catholic education for students in Kindergarten to Grade 8.
HSCS offers a strong academic program, including state-of-the-art Career & Technology Studies (CTS). In our safe and caring environment, students are encouraged to nurture and develop unique gifts and talents to reach their full potential. Modelling compassion and respect, our dedicated staff strive to meet the diverse needs of all learners. Holy Spirit Catholic School values social justice, community involvement and a commitment to lifelong learning.
This website will provide you with all of the information you will need if you are considering sending your child to Holy Spirit or if you already have a child enrolled. If you are looking for information, pictures, and vidoes about the events taking place at the school, please visit us at our Facebook page located at https://www.facebook.com/holyspiritcathschool
To subscribe to e-mails (SynerMail) sent by the school, please click on the following link: https://www.eics.ab.ca/parents-and-students/email-subscription-management
If you have any questions or comments, please direct them to Mr. Kucy (Principal) or Mr. Coles (Assistant Principal). Please use the e-mail form located under Contact.
School News View All
Safe Arrival - Pilot Project on Student Absences
Posted on Feb 23 2016
Dear Parents, We have been asked to pilot a new tool to report your child's absence. Currently you are able to report your child's absence by leaving a message on the school voicemail, or by emailing us via our school website. This new application…


text:
|Publication number
|Publication type
|Application number
|Publication date
|Mar 23, 1999
|Filing date
|Aug 1, 1997
|Priority date
|Aug 1, 1997
|Fee status
|Publication number
|Alfred J. Smetana, Jon Hayes, Kuo-Chen Yeh, Laura McCulloch
|Original Assignee
|Smetana; Alfred J., Hayes; Jon, Yeh; Kuo-Chen, Mcculloch; Laura
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (26), Non-Patent Citations (2), Referenced by (15), Classifications (14), Legal Events (6)
|External Links: USPTO, USPTO Assignment, Espacenet
1. Field of the Invention
The invention is directed to formulations for treating hypersensitive teeth and to methods for making and using such formulations.
2. Description of Related Art
Hypersensitive teeth can cause pain and discomfort when subjected to changes in temperature, pressure or chemical action. Exposure of the dentin frequently leads to hypersensitivity. Dentin exposure may occur due to recession of the gums, periodontal disease or improper dental care.
A significant breakthrough in the treatment of hypersensitivity came with U.S. Pat. No. 3,122,483 to Rosenthal. This patent reported that certain strontium compounds, especially strontium chloride, acted as desensitizing agents. Later, U.S. Pat. No. 3,863,006 to Hodosh reported that potassium nitrate could act as a desensitizer, and U.S. Pat. No. 4,631,186 and U.S. Pat. No. 4,751,072, both to Kim, reported that potassium chloride and potassium bicarbonate were also satisfactory desensitizers.
Ionic salt desensitizers, such as potassium nitrate and strontium chloride, appear to act by penetrating hypersensitive teeth through "tubules" in the dentin of the tooth. Dentinal tubules are small open tubes in the dentin that facilitate energy and material transfer between the interior and exterior of the tooth. The ionic desensitizers apparently interfere with the operation of the nerve in the tooth, reducing the nerve activity, and thereby reducing the sensitivity of the tooth.
Examples of ionic salts as desensitizers also include U.S. Pat. No. 3,699,221 to Schole et al., issued Oct. 17, 1972. This patent is directed to an early system for desensitizing teeth. The patent is directed to a strontium chelate in dentifrice, tooth powder, or chewing gum form. (A number of ingredients are listed in the toothpaste formulation, including 1% by weight "algin" in two examples. The purpose of the algin is not made clear.)
While the desensitizing properties of ionic desensitizers are excellent, such desensitizers are not "permanent," in that they do not remain in proximity to the tooth nerve forever, and the desensitizer must be reapplied to the tooth continually. In an effort to sustain the administration of an ionic desensitizing salt to the tooth, U.S. Pat. No. 5,188,818 to Merianos et al., issued Feb. 23, 1993, described a strontium salt of a maleic anhydride-methyl vinyl ether copolymer as a desensitizer. The polymer apparently adheres to teeth and releases the strontium over time.
A second class of desensitizing materials has recently been developed. This class of desensitizers acts to occlude or otherwise seal off some or all of the tubules present in the dentin and so reduce material and energy exchange between the interior and exterior of the tooth. These materials may have more or less affinity for the material in the dentin tubule and may exhibit more or less permanence as an occluding agent. Some materials migrate to the tubule quickly and are very prompt in occluding tubules, while other materials take time to develop as occluding agents. The materials may also remain in the tubules for varying amounts of time. Thus, the degree of occlusion of the many tubules found in dentin and the rapidity of the onset and the rate of decline of meaningful occlusion are important aspects of such occluding agents.
An example of an occluding agent is found in U.S. Pat. No. 5,270,031 to Lim et al., issued Dec. 14, 1993. This patent is directed to a tubule occluding desensitizer comprising a polyacrylic acid such as Carbopol� polymeric materials (B.F. Goodrich). Another tubule occluding composition is disclosed in U.S. Pat. No. 5,374,417 to Norfleet et al., issued Dec. 20, 1994. That patent discloses a potassium salt of a synthetic anionic polymer, such as a polycarboxylate.
One important aspect of desensitizing agents, whether ionic salts or tubule occluding agents, is that the agent must not be toxic or otherwise harmful to persons being treated for hypersensitivity. Preferably, a good desensitizing agent should be compatible with other oral care ingredients, such as conventional dentifrice or mouthwash ingredients, so that the agent may be administered in a conjunction with other dental therapies and prophylaxis. The organoleptic qualities of the desensitizing agent should also be pleasant to encourage compliance.
Although alginates have been known for some time as binders in dentifrice applications, we have now discovered that alginate salts are excellent occluding agents and meet all the requirements for a good desensitizing agent.
Alginates are salts of alginic acid, a polysaccharide having a molecular weight of about 240,000 daltons. The polysaccharide is extracted from giant brown seaweed and kelp. Alginic acid has been described as a linear polymer of β-(1-4)-D-mannosyluronic acid and α-(1-4)-L-gulosyluronic acid residues. The exact proportion of the monomers depends on the source of the polymer. The salts, typically sodium salts, of the acid are used as gelling agents and as thickeners in dentifrice applications and ice cream.
The use of alginate in a dentifrice system is demonstrated in U.S. Pat. No. 4,401,648 to Piechota. Jr., issued Aug. 30, 1983. This patent is directed to a dental creme containing a gel system of xanthan and alginate. The ratio of xanthan and alginate in the system is 1:3 to 3:1 and the system comprises 0.2-5% of the dental creme.
Alginates have also been used in conjunction with anti-caries agents as in U.S. Pat. No. 4,775,525 to Pera, issued Oct. 4, 1988. That patent is directed to a composition for reducing dental plaque. The essential ingredient of the patent is a calcium ion chelating agent comprising sodium alginate. Although the patent is directed to caries control, the composition may also contain a desensitizing agent such as strontium chloride.
U.S. Pat. No. 4,855,128 to Lynch et al., issued Aug. 8, 1989, is directed to plaque inhibitory agents in mouthwashes, toothpastes and other oral care systems. These agents are present from about 0.0025% to about 2.000% on a weight to volume basis, and are polysaccharides selected from xanthan gum, gum tragacanth (pectin), guar gum, gum karaya, chondroitin sulfate, polygalacturinic acid, sodium alginate and carrageenans of the kappa/lambda configuration. These ingredients apparently inhibit the coaggregation of bacteria and so inhibit the formation of plaque.
Alginates have been used in dentifice formulations for other purposes as well. The permeability of the enamel surface of teeth was reported in Tung, M. S. and Brown, W. E., "Characterization and Modification of Electrochemical Properties of Teeth," J. Dent. Res. 62(1):60-64 (Jan. 1983). The article reported that the permeability of teeth could be modified by anionic compounds such as phytate and alginate and by cationic compounds such as protamine, polyarginine, and polylysine, or by an alternating coating of these compounds. The purpose of this study was to investigate the behavior of incipient caries, which was reported to form below the enamel surface.
Another occluding agent is found in U.S. Pat. No. 4,645,662 to Nakashima et al., issued Feb. 24, 1987. This patent is directed to an oral composition for treating dentinal hypersensitivity. The composition contains aluminum and a carboxylate compound which combine to form a composition that occludes the dentin tubules. Among the binders that may be used in a dentifrice containing the occluding compounds are: carrageenan, cellulose derivatives (e.g., sodium carboxymethylcellulose, methylcellulose, hydroxyalkylcelluloses and sodium carboxymethyl-hydroxyethyl cellulose), alkali metal alginates (e.g., sodium alginate), alginic acid-propylene glycol ester, gums (e.g., xanthan gum, tragacanth gum, karaya gum, and gum arabic), synthetic binders (e.g. polyvinyl alcohol, sodium polyacrylate, carboxy vinyl polymer, and polyvinyl pyrrolidone), and inorganic binders (e.g., gelling silica, gelling aluminum silica, magnesium aluminum silicate (sold under the trade name Veegum), and synthetic hectorite clays such as Laponite (trade name)). The binder is added in an amount of 0.1 to 10% by weight, and preferably 0.2-5% by weight. The only reported example using an alginate, however, used one percent alginate and obtained unacceptable results. (See Example 2 and formulation #4 in Table 5.)
Despite the presence of occluding agents and other desensitizing agents, the search continues for an occluding agent that has the proper mix of desensitizing and organoleptic qualities to provide a meaningful therapy for treatment and relief of hypersensitivity while maintaining a pleasing "mouth-feel" for the therapeutic product. Alginates have not heretofore been recognized as desensitizing agents, even in desensitizing formulations.
The principal object of the invention therefore is to provide an effective tubule blocking agent and an oral care composition having a high degree of effectiveness in treating and relieving dentinal hypersensitivity, a negligible degree of toxicity, and a high degree of patient acceptance.
It is a further object of the invention to provide methods of delivering the oral care composition to the affected tooth or teeth in a manner to encourage patient compliance with the hypersensitivity control regimen.
It is still another object of the invention to provide methods of preparing the oral care composition in such a manner that the resulting formulation is safe, effective, stable and suitable from an organoleptic aspect.
It is an advantage of the invention that the alginates are compatible with fluorides and other conventional dentifrice ingredients.
Additional objects and advantages of the invention will be set forth in part in the description that follows, and in part will be obvious from this description, or may be learned by practice of the invention. The objects and advantages of the invention may be realized and attained by means of the instrumentalities and combinations particularly pointed out in the appended claims.
To achieve the foregoing objects and in accordance with the purpose of the invention, as embodied and broadly described herein, the invention provides an oral care composition for treating dentinal hypersensitivity comprising an amount of alginate sufficient to treat hypersensitivity when used in a therapeutic regimen.
To further achieve the foregoing objects and in accordance with the purpose of the invention, the invention further provides a method for treating dentinal hypersensitivity by administering to the affected tooth or teeth of a patient having dentinal hypersensitivity an amount of alginate sufficient to treat hypersensitivity when used in a therapeutic regimen.
To further achieve the foregoing objects and in accordance with the purpose of the invention, the invention further provides a method for making a formulation for treating dentinal hypersensitivity by combining a therapeutic amount of alginate with a carrier.
While this specification concludes with claims particularly pointing out and distinctly claiming that which is regarded as the present invention, the objects and advantages of this invention may be more readily ascertained from the following description of the presently preferred embodiments.
Reference will now be made in detail to the presently preferred embodiments of the invention.
The invention comprises a composition containing alginic acid or a derivative thereof for the treatment of dentinal hypersensitivity by application of the composition to teeth via a vehicle such as a dentifrice, mouth rinse, lozenge or chewing gum.
Alginic acid derivatives have long been known in dental applications as a binders, plaque inhibition agents or zinc ion complexing agents to improve associated organoleptic properties. Such derivatives, called alginates herein, include alginic acid itself and salts thereof, preferably alkali alginates and most preferably sodium alginate, potassium alginate, propylene glycol alginates, and ammonium alginates. Other known applications include use as a nontoxic bulking agent in food and a discrete single dosage unit for applications including mouthwash and chewable toothpaste.
The alginate should preferably be combined with a delivery system such as a dentifrice, mouth rinse or mouthwash, creme, lotion, oral gel, wipe or other known oral care delivery system for topical administration to teeth. While an alginate itself will act as a desensitizing agent without a carrier, direct delivery of the alginate is not favored for organoleptic reasons.
Desensitizing alginates may also be delivered in a dentifrice vehicle comprising alginate, abrasive, humectant, flavor, sweetener, detergent, other binders if required, and a fluoridating source if desired. Additional desensitizers, such as strontium and potassium compounds may also be included, but the presence of such additional ionic desensitizers is not expressly preferred at present. Alginates act as tubule occluders that may interfere with the migration of the nerve agents through the tubules. Alternatively, alginates may actually carry desensitizing ions into the tubules and then release the ionic desensitizing agents in the tubule.
Alginates can be used in a mouth rinse with humectant, sweetener, flavor, detergent and other actives as desired, such as anti-caries agents or antimicrobial agents. In a chewing gum alginates may be combined with other binders if required, humectant, sweetener, flavor and dye. Alginates may be used in a lozenge vehicle comprising humectant, sweetener, flavor and dye.
The relative weight percentage of alginate in any delivery system is, of course, a function of the dosage of the alginate and the dosage of the delivery system and the amount of time the delivery system stays in contact with the affected site. In dentifrices, for example, the alginate preferably comprises from about 0.01% to at least about 10% w/w of the dentifrice. Below about 0.01% by weight, the efficacy of the alginate is difficult to perceive, and above about 10% by weight little marginal efficacy is observed. Other than the organoleptic qualities of the dentifrice and the desirability of other dentifrice ingredients, however, there is no reason that a dentifrice could not contain more than 10% by weight alginates.
While a dentifrice containing the alginate may comprise no less than about 0.01% alginate by weight, the dentifrice should preferably contain no less than about 0.02% alginate, more preferably no less than about 0.5% alginate and even more preferably no less than about 1% alginate by weight. More preferably, the alginate should comprise no less than about 2% by weight of the dentifrice, and most preferably the alginate should comprise at least about 5% by weight of the dentifrice.
While a dentifrice containing the alginate may comprise more than 10% by weight alginate, there is little point in such a formulation as little additional occlusion occurs. Other ingredients are generally included in a dentifrice formulation that might suffer from excess alginate. More preferably, a dentifrice containing the alginate should comprise no more than about 8% by weight alginate, and even more preferably, no more than about 7% by weight alginate. As stated above, most preferably, the alginate should comprise about 5% by weight of the dentifrice composition.
A further possible benefit of alginate in oral care compositions such as dentifrices, is that the alginate may play a dual role of desensitizer and binder.
The process for making an alginate desensitizing formulation in accordance with the invention is to combine the ingredients for any conventional oral care delivery system with the alginate of the invention. The alginate may be added along with water or with any hydrophillic ingredient or ingredients in the preparation of the oral care delivery system through simple mixing.
The process for using an alginate desensitizing formulation in accordance with the invention is to use the oral care delivery system containing the desensitizing alginate. Thus, a patient should brush his or her teeth with the desensitizing dentifrice or rinse his or her mouth with a desensitizing alginate mouth rinse. The preferred embodiments of the invention will be set forth in more detail in the accompanying examples.
Prototype dentifrices containing sodium alginate were tested for tubule occlusion properties using an in-vitro model of dentin sensitivity first described by Pashley (J. Periodontology, Vol. 55, No. 9, p.522, September 1984). U.S. Pat. No. 5,270,031 to Lim et al., issued Dec. 14, 1993, also describes this methodology. Both references are incorporated herein by reference.
In this method, intact human molars free of caries or restorations were sectioned perpendicular to the long axis of the tooth with a metallurgical saw (and water lubrication) into thin disc sections about 0.6 to 0.8 mm thick. Sections containing only dentin and free of enamel were retained for testing. These sections were then etched with a EDTA (ethylenediamine tetra acetic acid) solution to remove the smear layer. The dentin discs were then mounted in a split chamber device as reported in Pashley, J. Dent. Research, 57:187 (1978). This special leak proof chamber was connected to a pressurized fluid reservoir containing a tissue culture fluid. By using a mixture of pressurized nitrogen and carbon dioxide gas, the fluid was maintained at physiological pH. To further simulate the intraoral condition, the disks were wetted with human saliva.
An air bubble was injected into a glass capillary tube mounted on a ruler or other measuring instrument, and the fluid in the capillary was placed in contact with the fluid behind the dentin disc. The bubble was displaced as fluid passed through the dentin tubules. By measuring the displacement of this bubble as a function of time, the fluid flow through the dentin disk was measured. (It has been reported that the fluid actually flows out of dentin tubules from the interior of a normal tooth.)
Following measurement of the baseline fluid flow in the dentin disk, the experimental mixture or dentifrice was applied to the external disk surface with a nylon brush. After a defined period of brushing, of about thirty seconds, the experimental material was rinsed off, and the post application hydraulic conductance was measured. In this fashion, the ability of alginates to obstruct fluid flow when used in a dentifrice was determined. The percent flow reduction induced by brushing with experimental materials was then calculated.
The dentin disc was then brushed for one minute with water and the fluid flow was measured. Finally, elevated back pressure was applied to the disc, and the tubules were "purged." The fluid flow was again measured. The purpose of this final test was to evaluate how tenaciously the tubule blocking agent (sodium alginate) maintained its effectiveness.
The formulation set forth in the tables was used to test the hydraulic conductance reducing abiligy of sodium alginate as a function of concentration. The sodium alginate selected was KELTONE LVCR�, a commercial product. The results are set in Tables 1 and 2.
TABLE 1______________________________________Formula CompositionINGREDIENTS WEIGHT PERCENT______________________________________Sodium Fluoride 0.232Sodium Saccharin 0.400Titanium Dioxide 1.500Sorbitol Solution 12.000Glycerin 20.000Silicon Dioxide 2.000Amorphous Silica 10.000KELTONE LVCR (Sodium Alginate) 0-7Sodium cocomethyl acid taurate 1.500Flavor 1.000Purified water Q.S. to 100%______________________________________
TABLE 2______________________________________Fluid FIow Reduction of Examples 1-8 Post Brushing Post Rinsing Post Purging Wt. % Fluid Flow Fluid Flow Fluid FlowExample Alginate Reduction Reduction Reduction______________________________________1 0% 20.6% 8.62% 11.76%2 1% 27.3% 9.46% 7.66%3 2% 57.5% 38.32% 23.44%4 3% 64.2% 40.36% 28.56%5 4% 75.3% 66.58% 42.1%6 5% 82.8% 65.44% 53.9%7 6% 90.6% 87.46% 79.94%8 7% 86.1% 83.1% 72.08%______________________________________
The following dentifrice formulations were prepared in the following manner. Purified water was added into a whipmixer mixer equipped with a vacuum system (a KORUMA mixer may be used for larger, i.e., pilot plant, batches). Key ingredients such as sodium fluoride and Triclosan, as appropriate, were added to the mixer, followed by sodium saccharin, titanium dioxide, and silicon dioxide. The resulting bulk material was mixed for approximately 10-30 minutes (under vacuum) followed by the addition of abrasive, alginate (KELTONE LVCR), premix (humectant and gum), flavor and detergent. Final mixing of 20-30 minutes was conducted under vacuum to deaerate the product. The resulting dentifrices had the compositions set out below.
TABLE 3______________________________________Formulations of Examples 9-16 Ex. Ex. Ex. Ex. Ex. Ex. Ex. Ex.Ingredient 9 10 11 12 13 14 15 16______________________________________Sodium MFP 0.83 -- -- -- 0.31 -- -- --Sodium -- 0.23 0.31 0.23 -- 0.23 0.31 0.23FluorideTriclosan -- -- 0.30 -- 0.30 -- 0.30 --Sorbitol 15.00 12.00 12.00 12.00 12:00 18.00 18.00 12.00SolutionSodium Sacch. 0.40 0.40 0.40 0.30 0.30 0.30 0.30 0.30Titanium 1.00 1.50 1.50 1.00 1.00 1.00 1.00 1.00DioxideAEROSIL 200 2.00 2.00 2.00 -- -- -- -- --Calcium Carb., 18.00 -- -- -- -- -- -- --HeavyGlycerin 12.00 20.00 20.00 10.00 10.00 10.00 10.00 10.00KELTONE 2.40 -- -- -- -- -- -- --HVCRKELTONE -- 5.00 5.00 5.00 5.00 5.00 5.00 4.50LVCRZEODENT 165 -- -- -- 4.00 4.00 3.00 3.00 4.00TIXOSIL 73 -- 10.00 10.00 10.00 10.00 10.00 10.00 10.00TEGO- -- -- -- 2.00 2.00 2.00 2.00 2.00BETAINEZFIGEPON 1.50 1.50 1.50 -- -- -- -- --TC 42Flavor 0.90 1.00 1.00 1.00 1.00 1.00 1.00 1.00Purified Water Q.S. Q.S. Q.S. Q.S. Q.S. Q.S. Q.S. Q.S.______________________________________
Several of the dentifrice formulations were evaluated for reduction of fluid flow. The results are set forth in Table 4.
TABLE 4______________________________________FIow Reduction for Certain ExamplesEx. #Principal Ingredients % Flow Reduction______________________________________ 9 KELTONE HVCR (2.4%); Sodium MFP 78%10 KELTONE LVCR (5%); Sodium Fluoride 83%(0.232%)15 KELTONE LVCR (5%); Sodium Fluoride 94%(0.31%); Triclosan (0.3%)16 KELTONE LVCR (4.5%); Sodium Fluoride 87%(0.232%)______________________________________
A lozenge for delivering the alginate comprised the following ingredients:
______________________________________Ingredient % wt/wt______________________________________Citric Acid 0.2Flavor and Color 0.3Sorbitol Seed 0.2Sodium Alginate 5.0Neosorb Q.S. to 100______________________________________
To form a chewing gum, the following ingredients were mixed:
______________________________________Ingredient % wt/wt______________________________________Chewing gum base (Dreyfus) 24.0Hydrogenated starch 11.5hydrolysateSodium alginate 3.0Water 1.9Flavor color 0.4Glycerin 1.0Lecithin 0.4Calcium saccharin 0.1Sorbitol Q.S. to 100______________________________________
The purpose of the above description is to illustrate some embodiments of the present invention without implying a limitation. It will apparent to those skilled in the art that various modifications and variations may be made in the formulations and methods of the invention without departing from the scope or spirit of the invention.
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|Oct 17, 1972
|Richard S Gubner
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|Jun 21, 1983
|Title not available
|Nov 1, 1973
|Jun 10, 1975
|William P Mlkvy
|Zinc and strontium ion containing effervescent mouthwash tablet
|Dec 3, 1974
|Oct 26, 1976
|Schole Murray L
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|Nov 8, 1977
|Pashley David H
|Desensitizing oxalate dental composition and method of treatment
|May 26, 1978
|Mar 27, 1979
|Reiichi Yamaga
|Pharmaceutical compositions for dental use
|Mar 29, 1982
|Aug 30, 1983
|Colgate-Palmolive Company
|Dental cream composition
|Jul 25, 1985
|Feb 24, 1987
|Lion Corporation
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|Dec 16, 1985
|Oct 4, 1988
|Ivo Pera
|Oral hygiene formulation containing sodium alginate
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|Warner-Lambert Company
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|Mar 30, 1992
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|Isp Investments Inc.
|Toothpaste composition containing strontium salt of maleic anhydride-methyl vinyl ether copolymer
|Nov 25, 1991
|Aug 10, 1993
|G-C Dental Industrial Corp.
|Odontotherapeutical materials
|Oct 17, 1991
|Aug 31, 1993
|Colgate-Palmolive Company
|Desensitizing anti-tartar dentifrice
|Sep 4, 1992
|Sep 14, 1993
|Kao Corporation
|Method of desensitizing hypersensitive dentin
|Dec 20, 1991
|Dec 14, 1993
|Block Drug Company Inc.
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|Oct 6, 1993
|Dec 20, 1994
|Colgate Palmolive Company
|Desensitizing dentifrice
|Jun 12, 1992
|Apr 4, 1995
|Yissum Research Development Company Of The Hebrew University Of Jerusalem
|Dental composition for hypersensitive teeth
|Jan 23, 1995
|Apr 23, 1996
|The Regents Of The University Of California
|Plasma and polymer containing surgical hemostatic adhesives
|Apr 11, 1995
|Dec 31, 1996
|Block Drug Company Inc.
|Dispersible particulate system for desensitizing teeth
|Dec 14, 1993
|Jan 28, 1997
|Block Drug Company Inc.
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|Jan 23, 1995
|Mar 25, 1997
|The Regents Of The University Of California
|Angiographic vascular occlusion agents and a method for hemostatic occlusion
|Aug 8, 1995
|Jul 8, 1997
|Enamelon Inc.
|Chewing gum compositions and the use thereof for remineralization of lesions in teeth
|May 23, 1995
|Aug 5, 1997
|Block Drug Company Inc.
|Dentinal desensitizing compositions
|Feb 2, 1996
|Dec 2, 1997
|Colgate Palmolive Company
|Two component dentifrice for the treatment of dentinal hypersensitivity
|Oct 29, 1996
|Feb 17, 1998
|Block Drug Co., Inc.
|Relief of dentinal hypersensitivity by submicron particles
|Feb 18, 1997
|Aug 11, 1998
|Collagenex Pharmaceuticals, Inc.
|Delivery system for administering dentin-hypersensitivity-ameliorating compositions
|Tung et al "Characterization and Modification of Electrochemical Properties of Teeth" J. Dent. Res. 62 (1) 60-64, Jan. 1983.
|Tung et al Characterization and Modification of Electrochemical Properties of Teeth J. Dent. Res. 62 (1) 60 64, Jan. 1983.
|Citing Patent
|Filing date
|Publication date
|Feb 19, 1999
|Jun 5, 2001
|Block Drug Company, Inc.
|Oral care formulation for the treatment of sensitivity teeth
|Feb 11, 2000
|Oct 1, 2002
|Charles F. Cox
|Acid resistant film forming dental composition and method of use
|Apr 29, 2002
|Dec 31, 2002
|Jeffrey S. Cox
|Acid resistant film forming dental composition and method of use
|Jun 13, 2001
|Jun 3, 2003
|Advantage Dental Products, Inc.
|Dental bonding formulation complexing calcified deposits associated with a dentinal tubule opening
|Apr 29, 2002
|Jun 24, 2003
|Jeffrey S. Cox
|Acid resistant film forming dental composition and method of use
|Dec 15, 2010
|Jul 21, 2015
|Glaxo Group Limited
|Compositions comprising alginates with high guluronic acid/mannuronic acid ratio for use in the treatment of dentine hypersensitivity
|Dec 21, 2005
|Jun 21, 2007
|Lynn Schick
|Taste masking of essential oils using a hydrocolloid
|Feb 25, 2010
|Pitcock Jr William Henry
|Tubule-blocking silica materials for dentifrices
|Jan 29, 2009
|Dec 23, 2010
|Gareth David Rees
|Oral care composition for combating dentine hypersensitivity
|Aug 25, 2011
|J.M. Huber Corporation
|Silica materials for reducing oral malador
|Sep 29, 2011
|Darsillo Michael S
|Antimicrobial Silica Composites
|Dec 15, 2010
|Oct 4, 2012
|Glaxo Group Limited
|Compositions Comprising Alginates with High Guluronic Acid/Mannuronic Acid Ratio for use in the Treatment of Dentine Hypersensitivity
|Jul 20, 2010
|Jan 27, 2011
|Glaxo Group Limited
|Novel composition
|Dec 15, 2010
|Jun 23, 2011
|Glaxo Group Limited
|Compositions comprising alginates with high guluronic acid/mannuronic acid ratio for use in the treatment of dentine hypersensitivity
|Mar 28, 2012
|Oct 4, 2012
|Glaxo Group Limited
|Novel composition
|U.S. Classification
|424/49, 424/448, 424/48, 424/435, 424/440
|International Classification
|Cooperative Classification
|European Classification
|Jul 16, 1999
Owner name: BLOCK DRUG COMPANY, INC., NEW JERSEY
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:SMETANA, ALFRED J.;HAYES, JON;YEH, KUO-CHEN;AND OTHERS;REEL/FRAME:010103/0735;SIGNING DATES FROM 19990622 TO 19990710
|Aug 29, 2002
|Fee payment
Year of fee payment: 4
|Aug 23, 2006
|Fee payment
Year of fee payment: 8
|Oct 25, 2010
|Maintenance fee reminder mailed
|Mar 23, 2011
|Lapse for failure to pay maintenance fees
|May 10, 2011
|Expired due to failure to pay maintenance fee
Effective date: 20110323


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Los Angeles - Michael Jackson's doctor was properly sentenced to four years behind bars in the star's death and should not be released on bail, prosecutors argued on Tuesday in a response to his bid for release while his case is appealed.
Dr Conrad Murray would be a danger to the community and a flight risk if he was released on bail or on his own recognisance with an electronic monitoring ankle bracelet, Deputy District Attorneys David Walgren and Deborah Brazil said.
Murray was convicted of involuntary manslaughter after a trial focusing on use of the anaesthetic propofol as a sleeping medication for the superstar. Jackson died of an overdose of the drug in June 2009.
Murray's four-year jail sentence is the highest term that could be imposed for that crime.
Reversal of conviction
Prosecutors said the sentence was appropriate under the circumstances and noted it was unlikely Murray would serve more than half that time.
"Michael Jackson died because of a totality of circumstances directly attributable to the defendant," the motion said. Murray had practiced "a form of highly dangerous and experimental medicine that directly resulted in Mr Jackson's death," it added.
"Based on his failure to accept responsibility for the decisions he made, his complete lack of remorse and lack of insight into the danger of his criminally negligent conduct, he remains a danger to the community," the motion stated.
It noted that he has many contacts outside the state and out of the country and could flee if released.
The motion also said Murray has not established the existence of any substantial legal question that might result in reversal of his conviction.
Unfair to keep him jailed
His lawyer, J Michael Flanagan, said in a motion last month that Murray knows he cannot work as a doctor but would find other employment. He suggested the sentence and Murray's mode of confinement is extremely severe for a man with no prior criminal record.
Murray is being held in solitary confinement and is chained to a table when he meets with his lawyers, according to Flanagan, who said Murray is extremely sorrowful about Jackson's death.
Flanagan conceded that Murray made some medical misjudgments but said he never intended harm to Jackson.
With Murray's appeal expected to take more than a year to move through the courts, the attorney said it would be unfair to keep him jailed in the interim. His appeal has not yet been filed. Conceivably, he could serve his entire sentence before the appeal is decided.
A hearing on the motion was set for Friday.
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Digital music service Spotify rolled out new features and said it increased the number of active users at a press event that featured a special musical performance by Frank Ocean.
Spotify now has 20 million active users worldwide, up 33 percent in less than six months. The company counts five million people among paying subscribers, a 25 percent increase during the same time period.
Spotify also revealed it has one million paid subscribers in the United States, that it added a Twitter like functionality that allows users to follow one another, and that the rock band Metallica's music was now available on the service.
The company made the announcements at a splashy New York event on Thursday that included a conversation between Spotify backer Sean Parker and Metallica drummer Lars Ulrich.
Ulrich's appearance is notable since his band was one of the leading crusaders against Napster, the digital music sharing company co-founded by Parker more than a decade ago that was a flashpoint for digital rights and artist compensation.
"We have more in common than the whole thing that happened 12 years ago," said Ulrich about Parker.
Ulrich said the decision to join Spotify coincided with the fact the band now owns its entire catalogs of music.
Spotify, which strikes royalty deals with record labels, has paid more than $500 million to the music industry since its launch four years ago - an amount that has more than doubled in the past nine months. It pays roughly 70 percent of its revenue back to rights holders.
"The more music that gets shared the more money goes back to artists," said Daniel Ek, CEO and co-founder of Spotify.
Spotify is a free on-demand streaming music service that is rising in popularity. People can pay to hear music without interruptions from advertising and the ability to play lists and preferences from any device any time.
The company has struck up a partnership with Facebook (FB.O) - Parker is Facebook's founding president - that allows listener's to display their music choices on their personal pages.
Streaming music services such as Spotify and Pandora (P.N) are being carefully watched by the music industry concerned over the royalty payments.
For example, Pandora is pushing the Internet Radio Fairness Act, which would change how royalties are paid to artists. As of now, online streaming music companies like Pandora pay a different rate to license music than say traditional radio companies.
Many of music's most notable names like Billy Joel and Rihanna are opposing the proposed change.
Trending On Reuters
Movie Review: Dishoom
In Rohit Dhawan' "Dishoom", the opening credits roll to a rap song mouthed by two brawny protagonists who describe themselves as "simple" men disappointed in love who prefer home food to eating in five-star hotels. With one disclaimer: these otherwise meek men turn violent if someone doesn't stand up while India's national anthem is playing, criticizes the country or harasses a woman. Full Article
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Jeff Driskel had somewhat of a rollercoaster run with Florida football. He was projected as the "Next Tim Tebow". Driskel started for the Gators as a sophomore and performed with strong statistics. He won 10 games with a 63.7 completion percentage, 12 touchdowns versus five interceptions, and 408 rush yards. …Read More »
Jaguars Pick 5th in Thursday's NFL Draft
From fans, to analysts, to sports writers, and more, everyone has their opinion on who is going where come Thursday's NFL draft. With mock drafts swarming the internet and thousands of opinions and thoughts floating around, it's hard to really know what's going to happen. What we do know, however, …Read More »
Mark Schlereth Talks NFL Offseason
The first two picks of Thursday's NFL Draft likely won't come as any surprise, with quarterbacks Jared Goff and Carson Wentz seemingly destined to go No's. 1 and 2 in some order to the Los Angeles Rams and Philadelphia Eagles. The suspense goes away when two teams with holes at the QB …Read More »
NFL Draft Preview: Cris Collinsworth
'Tis the season for Mock Drafts. While that's definitely not how the song goes, it's hard to deny the truth of the above statement with the 2016 NFL Daft approaching in just two days. Whether by fans or by analysts, mock drafts have taken over the internet and television the …Read More »
NFL Draft Preview: Paxton Lynch
Paxton Lynch has been undervalued his entire football career. Coming out of Trinity Christian Academy in Deltona, Florida, he was under recruited and left to Memphis to play for Justin Fuente and the Tigers. Now, heading into Thursday's NFL Draft, he is considered by many draft experts to be the …Read More »
NFL Draft Preview: The Miami Dolphins
The 2016 NFL Draft has already seen some blockbuster trades made prior to the big event Thursday night. Crunch time is on for the Miami Dolphins with the focus on the running back and cornerback positions with the 13th overall pick. Depth is a concern at the cornerback position with questions of …Read More »
Four-Game Suspension Reinstated for Patriots QB Tom Brady
It's been over a year since the AFC Championship game that started "Deflategate", and the scandal is back in the news with a major plot twist. A U.S. Appeals Court has reinstated the NFL's four game suspension of New England Patriots QB Tom Brady for his supposed role in "Deflategate", in which he allegedly …Read More »
Eagles, Browns Look to Reshape Future With Draft Picks
Howie Roseman can't commit to chocolate or vanilla. He likes both and he's fine with both. The Philadelphia Eagles' executive vice president of football operations spoke on Thursday about the blockbuster trade between his organization and the Cleveland Browns. Now in sudden possession of the No. 2 overall pick of …Read More »
2016 NFL Draft Nears, Deals Made
With the NFL draft kicking off in just eight days, deals continue to be made as teams jockey for draft position. Today, the Philadelphia Eagles swung a trade with the Cleveland Browns that will allow them to have the second pick in this year's draft, and most draft experts believe …Read More »
Current NFL Player Trenton Brown Pursuing College Degree
Trenton Brown… some know him as an offensive tackle, others as a big kid with a kind heart and a sense of humor. Nicknamed Trent by his family and friends the young NFL player with a bright future is so much more. Professional athletes are highly esteemed and looked up to …Read More »


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Welcome to The Pop Culture Network
Thursday, July 28 2016 @ 10:59 PM CDT
Wednesday, September 16 2015 @ 04:21 PM CDT
|This October, Captain America takes up the shield once more. Today, Marvel is pleased to present your new look at SAM WILSON, CAPTAIN AMERICA #1 – the explosive new series from Nick Spencer (Ant-Man) and Daniel Acuña (Uncanny Avengers)! When Steve Rogers was restored to his natural age, he chose only his closest and most trusted ally to take up the mantle of Captain America. Now, as the Marvel Universe charges forward into a new age, the Avenger formerly known as the Falcon stands proud as the one and only Captain America! Yet eight months have passed, and these two former friends now find themselves on opposite sides. What could have happened to divide them? More importantly – who will you stand with? New friends, new foes, and a new beginning for Sam Wilson this October in SAM WILSON, CAPTAIN AMERICA #1!
Wednesday, September 16 2015 @ 04:17 PM CDT
|SPECIAL GUEST PETER (Spy Vs. Spy) KUPER presents the wordless story "One Dollar!" See how one little piece of paper can lead to chaos. Then, actor Gil (Buck Rogers) Gerard accepts a strange role in "Welcome to the Con" by Jeffrey Kaufman! Citizens regret a government sponsored open forum in Paul Bradford's "Unpropitious Fate!" Alien gladiators battle to the death in Troy Vevasis' "The Duel!" In Terry Cronin's "Horse Power G" humans talk about their horses — and the horses talk about them! Street races turn deadly in "Speed Demonz" by Gabe Lamberty! Dark plans place hens in indentured servitude in Rick Bonn's "Farm Noir!" K.J. Murphey's tale relates how a trapper seals his fate in "A Weindigo Curse!" The book with the best story and art from independent comic book creators celebrates it's landmark 10th issue!
Wednesday, September 16 2015 @ 04:04 PM CDT
Thursday, September 10 2015 @ 11:07 PM CDT
Friday, September 04 2015 @ 10:04 AM CDT
Tuesday, September 01 2015 @ 12:51 PM CDT
Monday, August 31 2015 @ 07:33 PM CDT
Monday, August 31 2015 @ 07:04 PM CDT
|This September sees the launch of a brand new mini-series, Bloodthirsty, a visceral revenge thriller that merges the real-world hopes and horrors of a post-disaster community with an engaging thread of political corruption, class divide and blood-curdling terror! Written by screenwriter Mark Landry, and illustrated by Ashley Witter (Interview with the Vampire, Squarriors), the giant-sized debut issue drops in September.
Monday, August 31 2015 @ 06:49 PM CDT
Thursday, August 27 2015 @ 11:15 PM CDT


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Loïc Duval, Tom Kristensen and Allan McNish took the No. 2 Audi R18 E-Tron Quattro to victory at this weekend's Six Hours of Austin at the Circuit of the Americas, marking the 12th victory for the R18 body and the 100th LMP overall victory for Audi since 2000. The milestone victory also saw a second R18, driven by Marcel Fässler, André Lotterer and Benoît Tréluyer, take third place.
Audi's 100th LMP Victory at 6 Hours of COTA
- Volvo shoots for self-drivers by 2021
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- Find Parts & Accessories for your vehicle!
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Hmm just told Aaron is mickeys birthday today, his reply was how old is minnie, i say i dont know so he pipes up well you should have asked her...
Thankyou ste! Im loving the happy birthday notice to!
our little welsh wonder!!
Well done Ste ;):hug2:
I have been lucky enough to see them quite often, living in the far north of scotland if the conditions are right we see them! They are stunning :)

<table width="350" bgcolor="#FFFFFF" cellpadding="1" border="0" cellspacing="0" style="background-color: white;...
ooohhh josh thanks for all that :wave:
not sure yet if we will get or not but in the very early stages of planning, but hey im female i dont take no for an answer lol!!
I have looked...
have heard a few people recommend this so will def take a look, thanks :p015:
hmmm i wonder if i know any welsh people.....;)
Shopping is already on the list :lol:
Hi Guys
Im in the very early stages of planning a possible trip to Ney York next Feb and looking for any advice you can throw at me lol! Where...
*and a big jug of milk...*
*passes round yummy cookies*
mmm just made these...they are very very yummy....:p015:
We arent to bad a bunch are we :yes:
hiya i live up in the highlands and you can rent log cabins for holidays on the edges of loch ness - see if you can spot nessie tho she is a wee...
we saved a bit of cake just for you tink ;)
well the baby has had a fantasic day, the rain held off and his party was fab! talk abotu being spoilt!! he is one very lucky boy.
Cant believe...
My gorgeous wee nephew is 4 today! Cant believe how quickly he is growing up. Was down last night and helped my sister get ready for his party and...
Separate names with a comma.


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Overloaded operators exist when an operator or operation has different meanings in different contexts. This usually applies to variables and sets, but it can be true for people, too. These people try to do the work of many different roles—and usually fail. If you have an overloaded people operator, analyze the work and try to divide it up.
Being aware of risk is good project management common sense. But to address risk quickly and effectively when you encounter it, the best method is to establish clear, agreed-upon, communicated responses to risk before it even happens. Dave Browett suggests some tactics to mitigate and confront risk you can use with your team.
Kanban, a highly effective agile framework, is based on the philosophy that everything can be improved. And it's not just for development teams. The QA team also can use kanban to organize tasks, identify bottlenecks, and make their processes clearer and more consistent.
Think about the common practices of an agile team: daily stand-up meetings, retrospectives after every sprint, pair programming and buddy reviews, collaborating with customers, and more face-to-face time instead of mountains of documentation. What is the agenda behind all these operations? Frequent and open communication.
Status accounting is following the evolution of a configuration item through its lifecycle. Using application lifecycle management along with agile helps prevent mistakes, but lets you have the minimum amount of red tape; the team achieves an acceptable velocity without being unduly burdened with too much process.
While the technical complexity of real-world ALM may be substantial, sometimes the people issues present even more complex challenges. Being able to understand the personalities and work culture of the folks doing the work can help you implement ALM in a comprehensive and effective way.
We know the importance of quick feedback cycles in our builds so we can fail fast, and feedback from the end-user. But sometimes even agile teams forget the importance of feedback from other team members. This article details several methods for eliciting feedback, as well as how to pick what's right for your team.
Many teams think they are agile in their projects, but if you're not receiving and analyzing feedback regularly, you're not really agile. Plotting the feedback you get on a chart throughout your sprints can help you see whether you have a lag. Read on to learn how to gather and use your feedback to be truly agile.
The elves working on Project Santa—you know, the big delivery that happens every December 24—have decided to go agile. But Santa, the product owner, is busy and not always available to answer questions or provide guidance. What kind of suggestions and improvements should they address in their retrospective?
Leaders in agile organizations should consider adding lean techniques to their DevOps practices. Lean thinking can accelerate DevOps delivery by providing a set of processes and principles to help create more beneficial products, save money, boost productivity, reduce waste, and map to value.
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Panasonic GH2 14-140mm F/4.0-5.8 Aspherical O.I.S ED for sale $450 /w Zoom lever
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AttilaTheHun OP • Forum Member • Posts: 63
Panasonic GH2 14-140mm /w Zoom lever Price drop!
In reply to AttilaTheHun • May 16, 2012
Lower price, $420
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Deal of the Day: "M*A*S*H: The Complete Series + Movie" on DD
Today only, save big on this M*A*S*H bundle, which includes all 11 seasons of the hit television show and the feature film. This offer ends at 11:59 p.m. (PT) on Wednesday, July 27, 2016. Learn more
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In terms of visual atmosphere alone this film is an anomoly in the teen romance genre, and it also has a way of capturing casual moments by having participants in a group conversation expressing themselves with body language and facial expressions when others are speaking which creates a great sense of authenticity that I don't think I've seen since Crazy/Beautiful, which is still for my money the most poignantly realistic teen movie ever made. There's a minimal use of one-shots during conversations, and when they are used the transitions from one person to another aren't timed directly with when they start and stop speaking, so there's no reaction shots, it's all fluid. It creates a sense of everyone being in the moment instead of solemnly waiting their turn to speak and emote.
Visually the washed-out color, shaky cameras, and oddly framed shots are the opposite of what you'd expect from an MTV-style film featuring Ashlee Simpson. Actually focussing on the camerawork it seems maybe contrived, but for most of the movie it inconspicuously plays a vital part in adding mood and creating a portrait of the city at night which is as enchanting as anything in Lost In Translation.
Steven Strait's brooding singer-songwriter character is a bit of a caricature and Clea's description of him ("Luke has integrity. He wants to make it, but on his own terms.Read more ›
But everyone has to start somewhere, as the theme of the story points out. The plot is thin - boy meets girl in New York, both craving the entertainment industry, both move to Los Angeles, both get caught up in the negative as well as the positive aspects of the climbing to the top life in LA, both are influenced by friends and family, choices are made, stuff happens. This trickle of dialogue is parceled out between songs by a group of wannabe actors, some better than others. Of the group Kip Pardue shows his more extensive experience and lightens the screen. But the rest is, at best, a series of tryouts told at a pace that assures somnolence. But everyone has to start somewhere.... Grady Harp, December 05
The best part is the skateboard dog and the goods looks of Steven Strait, but if you really wanna enjoy him, i better recommend you THE COVENANT. Is the typical horror flick, but at least, is not so presumptuos that this one.
Ashlee Simpson: Actually surprisingly likeable considering it's her.
Kip Pardue: The most interesting and likeable thing about this entire flick.
Soundtrack: Not too bad, but it isn't my cup of tea despite some strong INXS resemblance.
The Plot: Slow, predictable, and at times really silly. Pell James is pretty, but she looks like any other girl her age, and Steven Strait is trying too hard to be a universally liked Johnny Depp.
My rating: Imagine the sound of the buzzer after three wrong guesses on Family Feud. Sorry, you guys, but this movie just wasn't worth the five bucks I spent when I bought it off the previously viewed rack.
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It's a really cute family friendly movie great music and so funny. I really enjoyed this movie. I will watch it over n over again.Published on March 6, 2014 by Sonja L Hardin
Undiscovered is a great movie. Really funny and the music is great. The DVD was packed great and came in great condition.Published on February 5, 2014 by lenaava21
I loved this movie!! It has everything a girl needs, eye candy, good music, and Steven Strait!! Need I say More?!Published on December 5, 2013 by Amazon Customer
I don't care what you say but this is an awesome movie! I wish they hadn't stopped selling this movie and they came out with it on blueray ;)Published on December 2, 2012 by Shane


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Comment Re:So glad I missed out (Score 4, Funny) 528
I was going to upgrade, just to see what it was like. First I tried to take a clone of hard drive, but somehow, during that process, my motherboard died and so I was without my laptop while it got repaired.
Your computer chose death over Windows 10.