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Katie Hand London, Summer 2011 - UK Today Program
Katie's Posts
The View of London from Indiana
My experiences are so valuable because of how I understand them. The cultural differences between London, the U.K., and England and Indiana, Lawrenceburg, and the United States are what make me appreciate the composition of all of these places even more than before I left.
England, London, London Study London, Post-departure, Returning home, summer
What did I do wrong now?
In this city, I definitely learn something new every day. There have been some surprising cultural differences that I and other people in the IES program have noticed or learned the hard way.
eating, England, London, London Study London, Pubs, restaurants, summer, Tube
I'm studying LONDON, isn't that enough?
It's easy to forget about the "studying" part of studying abroad.
Barcelona, classes, Classwork, England, London, Summer Blogs
Keep Calm and Carry On
My time in London thus far has proven that I am also not a direct enough person: I can now honestly say that I am intensely and strictly unlucky.
Seeing the UK
I've been in London for a week and a half now and I am learning new things about the place every day, hour, trip.
Day trips, England, Field Trips, London, London Study London, summer
Life, Liberty, and the Pursuit of Coffee
Naturally, the significance of my most extraordinary life experience yet did not sink in until I began to worry about where I will be getting my daily coffee.


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Ways Together provides a look through the camera's eye at people interacting in the modern cafe scene. The author questions the influence of communications technology in today's culture — does it push us apart or does it ultimately draw us closer together?
Street photography, color, 7x7 inch, 80 pages. Available hardback or paperback.
A book review by Mark Roberts:
Video of the book signing at ModernBook Gallery, Aug 2, 2012:
My interest is to see the world around me—expressions of people and the artifacts of our modern culture.
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Ways Together Publicado 21 de junio de 2012

subset: commoncrawl


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Simi Garewal show
5 Simi Garewal show Articles
Simi Garewal launches website to connect with fans4 years ago 4
The veteran actor is making her presence felt in the cyber world Though it has been years since Simi Garewal was last seen in a film, she has been… Read Article ▶
Simi Garewal, happy birthday!4 years ago 0
The yesteryear diva who revived her career as an eminent television personality hosting some of the most watched talk shows, celebrates her 65th… Read Article ▶
Priyanka Chopra wants to kiss Deepika Padukone!5 years ago 0
Now that's a dostana we would love to see! Won't you? Priyanka Chopra and Deepika Padukone are two of the most in-demand female actors of… Read Article ▶
Shahrukh Khan can never keep a secret!5 years ago 1
The weekend is full of treats on the telly and we watched one such on the Simi Garewal show when Hiroo Johar talked about her son Karan Johar. Never… Read Article ▶
Bobby Deol is a bully!5 years ago 3
This is what we learned from Abhay Deol as he spoke to hostess Simi Garewal on her talk show... Host Simi Garewal's 'Kiki' antics on India's Most… Read Article ▶


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TV star and best-selling author Dr. Ian Smith said calorie cycling and high-intensity interval training can help you lose weight more quickly than conventional, linear dieting or long, drawn-out cardio workouts.
In an exclusive Eaminer interview, Dr. Smith explained why calorie disruption delivers rapid weight loss, and how his new book, Super Shred: The Big Results Diet, can help you lose 20 pounds in four weeks.
"When your body gets the same amount of calories every day, you increase your body's efficiency at burning calories and decrease calorie burn," said Dr. Smith, a nationally recognized obesity expert and frequent guest on the "Dr. Oz Show."
Calorie Disruption Revs Up Metabolism
Dr. Smith said changing up your caloric intake every day keeps your metabolism stoked. In his "Super Shred" program, dieters consume 900 calories on some days and 1,600 calories on other days during a four-week period. The calorie intake changes daily.
What this does is keep your metabolism revved up by confusing your body so it never gets used to one diet. The result is rapid weight loss in a short amount of time. "This is a program if you want fast results, like if you want to look good before a wedding or a beach vacation," he said.
Dr. Ian outlines the meal plans in his program, so there's no guess work involved. "I do the calorie-counting for you, so you don't have to," said Smith, who said his meals combine a healthy mix of protein, fat and carbohydrates so you feel satisfied.
While low-carb diets have become extremely popular as a way to drop weight quickly, Dr. Smith isn't a fan of extreme carb restriction. "We need carbs, but you should focus on choosing the right carbs," he said.
In addition to calorie disruption, another component of Dr. Ian's program is meal spacing, or eating small meals frequently throughout the day. In "Super Shred," dieters eat four small meals and three snacks spaced two to four hours apart to curb hunger.
"Meal spacing is extremely important because it keeps your hormones and insulin levels even to prevent blood-sugar spikes," said Smith, author of the No. 1 New York Times bestseller, Shred: The Revolutionary Diet. "It also prevents you from gorging on your next meal, which happens a lot on other diets."
HIIT Burns More Calories and Torches Belly Fat
Smith, a Harvard University alum who graduated from Dartmouth Medical School, is also a proponent of high-intensity interval training (HIIT), which has been shown in numerous studies to burn more calories and belly fat than long, drawn-out cardio sessions done at a middling pace.
Dr. Smith, who offers his "Shred 27 Burn Workout" exercise DVD on his website, said HIIT also helps you burn more calories for up to 24 hours after you stop exercising.
"After following my Super Shred program for four weeks, hopefully you will adopt lifestyle changes that will keep you fit and healthy for the rest of your life," he said. "That is my goal."
Yummy butternut squash and apple soup recipe from Super Shred
- 2 tablespoons unsalted butter
- 1 red onion or other sweet onion, peeled and chopped
- 1 large clove garlic, peeled and smashed
- 1/8 teaspoon ground nutmeg
- 1 cup cubed, peeled apple (Fuji or Gala)
- 2 pounds butternut squash, peeled and cubed
- 3 cups low- sodium chicken stock
- 1 teaspoon ground cumin
- ¼ cup fat- free evaporated milk
- Salt and pepper
In a large saucepan or pot, melt the butter over medium heat and add the onion and garlic. Sauté until soft, about 5 minutes. Sprinkle the nutmeg on the apples and add to the saucepan. Stir constantly for 2 minutes.
Add the squash, stock, and cumin, and bring to a boil. Reduce heat and let simmer until the squash is tender. Transfer to a food processor or blender, add the evaporated milk, and purée until smooth. Return to saucepan and let simmer on very low heat for 5 minutes. Add salt and pepper to taste.
Suggested Links
- Dr. Oz reveals inexpensive anti-aging wrinkle creams and weight loss secrets
- Tim McGraw is ripped to shreds at 48: His Paleo diet and CrossFit workout
- Dr. Oz's two week rapid weight loss diet: Lose 9 pounds in 14 days
- Kim Kardashian's ketogenic Atkins diet speeds weight loss and starves cancer
- Ketogenic diet beats chemotherapy for almost all cancers says Thomas Seyfried


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AMA planned a campaign to remind doctors of ethical guidelines limiting their acceptance of gifts from pharmaceutical companies. The campaign was to be sponsored by Eli Lilly Corporation. (USA Today, 4/27/01, Drugmakers bankroll ethics guidelines on 'freebies)
In 1997, the American Medical Association agreed to endorse products made by the Sunbeam Corporation. The five-year agreement would have placed the AMAs logo on a line of thermometers, blood pressure monitors, and other home healthcare products and generated millions of dollars in royalties for the medical group (New York Times, 8/13/97, p. A1). However, the AMA hadnt evaluated the quality and cost of the products (New York Times, 5/17/97, p. D6). As a result of media publicity and concerned AMA members, the deal was scrapped and five of the groups executive leadership left the AMA (New York Times, 9/20/97, p. D2; Chicago Sun Times, 11/1/97, p. A1). Subsequently, Sunbeam sued the AMA for breach of contract and won a $9.9 million settlement. (Medical Industry Today, 8/4/98)
The Chicago Sun-Times reported that in early 1996 Procter & Gamble/olestra, through its PR agency, gave the AMA a check for $800,000 in partial support of an AMA fitness program; the check, which was later returned, came after the AMA issued a statement endorsing the FDAs approval of olestra. (AMA press release, Jan. 1996; Chicago Sun-Times, 11/26/97, p. 70)


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Fort Wayne flourishes along the St. Joseph, St. Mary's and Maumee rivers as the second largest city in Indiana. The Holiday Inn Express® Fort Wayne - East (New Haven) hotel is just off I-469, five minutes from downtown. Historic attractions, museums, parks and dining surround our hotel's property in Fort Wayne, Indiana.
This hotel is close to the highway and near major corporations, including Parker Hannifin and Norfolk Southern.
View More
This hotel is close to the highway and near major corporations, including Parker Hannifin and Norfolk Southern. Stay connected to the office with free high-speed, wireless Internet access in every room and a 24-hour Business Center. We also offer executive-level rooms and meeting facilities for our hotel's valued guests.
In Fort Wayne, Indiana, walk the Rivergreenway Trail, stopping at popular historic sites like Johnny Appleseed's gravesite. Spend an afternoon with a tour of the Fort Wayne Museum of Art, a leisurely stroll through the open-air Jefferson Pointe Shopping Center or a matinee at the restored Embassy Theatre. Stunning river views and impressive architecture create the perfect backdrop for an evening excursion.
Guests love the hotel's friendly, responsive staff and great amenities. Prepare for your day at the complimentary, hot Express Start Breakfast Bar. You can slip into the heated, indoor pool or work out in the well-equipped Fitness Center to melt stress. Join us in Fort Wayne and "Stay Smart" at the Holiday Inn Express® Hotel Fort Wayne - East.
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2014 - Oredigger Classic - CSM Campus
Submitted by David on
Photographers TT
- Sportif Images
- Racer Shots
- Shot William
Results TT
Photographers Crit
- Sportif Images
- Shot William
29 Comments
Race Booth
Submitted by Christopher Agu... (not verified) on
Hello my name is Christopher and I am owner of BambuCycles in Denver and we are interested in being at your event. Please contact us, 303-455-3792.
Points: 37
Where are the results???
Submitted by Father Time (not verified) on
Where are the results???
Points: 62
Race Results
Submitted by Drew Christopher (not verified) on
Check out all this, and every weekend's race results here: coloradocycling.org
Points: 62
It's amazing that pictures
Submitted by Erik (not verified) on
It's amazing that pictures can be released before the results! How can you have a time trial hill climb and not give results at the end of the race.
Points: 38
No results...and, when asked
Submitted by Becca (not verified) on
No results...and, when asked about podiums, the reply was, "Were trying to find the money." Um....did you forget you were sponsoring a race?
Points: 19
Agreed. The organization of
Submitted by fred (not verified) on
Agreed. The organization of this race was poor - it was fiasco to not have any results posted after the race - and still no results yet. It's great to support the CSM cycling team, but you have to do the due diligence if you sponsor a race and collect all of those fees.
Points: 48
I got my Start Money!
Submitted by Former Road Racer (not verified) on
No problems, as I got my Start Money. I feel sorry for you that rely on prize money. Suckers!
Points: 43
$12,000 in the Bank
Submitted by Making Bank (not verified) on
Let's say the organizers make $12,000 GROSS to do a very simple task. close one road, and know how to use a timing system. That is it. Clowns will pay money to simply get a result on the internet. That is all they want, and timely. For $40 each, I will say "start, stop" and give you a time and place. This is the best money-making model yet, and this organizer blew it. I say boycott them forever.
Points: 21
Haha, you guys are whining
Submitted by mjh (not verified) on
Haha, you guys are whining about a college race.
Points: 29
Submitted by boratbuff (not verified) on
I love it when they combine the men's 3's and 4's into one start time. Not. 74 starters, 11 finishers, 63 DNPs. Now that's just awesome.
Points: 67
tuff luv
Submitted by Randy Savage (not verified) on
If you're not on the podium and it's not a "series" race, what difference does it make if you were officially listed as DNP? It just lets folks know you didn't finish on the lead lap. Besides, it's the race experience that matters most, right?
Oh, that's right... you can't brag about it or share your "online" results w/ friends/family/coworkers.
Points: 43
Missing the point
Submitted by boratbuff (not verified) on
My point being, cat 4s should have their own start time, they shouldn't be expected to compete with cat 3s in a crit, or any other race for that matter. Of course cat 4s are going to DNP against cat 3s. That's why there is a distinction between a cat 3 and a cat 4. 4s after all are the largest category. I know, you want to keep the number of start times as low as possible, but if any category deserves it's own start time, it's cat 4. Anything worth doing is worth doing right, so the saying goes.
A few thoughts
Submitted by Stephen Fitzgerald (not verified) on
To Randy Savage - I don't get why so many people are down on folks who want to know how they placed, even if they are way off the podium. They trained, they showed up, they paid up, they didn't quit, and they want to know how they stacked up against their piers. When you are hanging on by a thread it feels great to say that you got whooped but still beat 50% of the field.
Only a small percentage of racers get near the podium but that doesn't mean the efforts of the rest field are worthless. Everyone races for their own reasons. Each individual's efforts makes the overall race a better experience. If people want to brag online about 26th place to their friends and family they certainly earned the right with the $45 they paid didn't they? (Counter point, we all knew there wasn't a finish camera before we started, and should have kept our expectations for accurate results low.)
To Borabuff - I certainly don't argue with 4s having their own race, but I'll bet the turnout expectations were low or the race day schedule was constrained so they merged for the sake of efficiency.
Bonus trivia fact for the 3/4 race: If you toss out the outlier result of the winner who lapped the field and could probably place with the pros, the other top three finishers were in fact cat 4s. The cat 4s showed the 3s a thing or two yesterday.
Points: 73
One more point
Submitted by boratbuff (not verified) on
Well said, Stephen. One point though. Yes, 3 of top 4 were cat 4s, but 7 of the 11 finishers were cat 3s. And Randy Savage, yes it is about the race experience, but I'll tell you it wasn't a fun experience yesterday getting crushed/lapped by a cat 3 halfway through the race. I have a feeling you weren't in that field yesterday as a cat 4 or you'd probably be a little more sympathetic. Ok, I'm done whining, the CU crit this Sunday is also combining the 3s and 4s. I just think that the college race promoters would get even more turnout and thus more money if they gave 4s their own start time. Good luck to the 4s on Sunday, I'll be training on my own trying to compete with the 3s, definitely not paying good money to get crushed by cat 3s.
Points: 47
Here's the thing, I'm not
Submitted by Randy Savage (not verified) on
Here's the thing, I'm not (nor are others, I'd bet) saying that the efforts of the finishers who don't podium aren't meaningful. What I AM saying is that it is the race, not the online posting of results, that matter most. If you finish a race and don't have a sense of how well you did (and I don't mean finishing place) and haven't already felt that sense of satisfaction that you gave your all, then that's on you. When you're really suffering, it feels good to whip half the field. Saying you whipped half the field is self-absorbed/bragging. And no, you don't earn the right to brag about online results just by paying your entry fee.
It seems that the folks who complain about lack of online results are the ones who are diminishing their own efforts as they're the ones who are satisfied only if they can see the proof. Your feelings in the first few meters after the finish line should be all you need. The rest is just gravy.
Points: 59
Same day results are an
Submitted by billy jean (not verified) on
Same day results are an expectation for nearly everyone who pays an entry fee. Anything less than that is not acceptable. Glad that your reasons for racing are important to you.
Points: 36
Glad you can admit they're an
Submitted by Randy Savage (not verified) on
Glad you can admit they're an expectation, but not a right. Do you really find that any time your expectations aren't met, it's unacceptable?
Points: 27
DNP vs. DNF
Submitted by MJ (not verified) on
Mr Savage, the whole point of a "Race" is to see how you stack up against others. Plain and simple. If I didn't care about that, I wouldn't pay ~$40 per race on top of the nearly $100 in annual license fees now. So to not even score/place nearly 90% of the field (all of whom paid to race) is ridiculous. I've been on/off the podium, won races, and even dropped out before. My results should reflect whether I gritted it out for a top 15 finish, won the frickin thing, or dropped out halfway thru. So when the organizers are too lazy and/or disorganized to even try and score the field, people have a right to complain.
They didn't even bother to distinguish between a DNF and a DNP. Meaning, 12th place is viewed the same as a guy who gets pulled or drops out after 2 laps. How is that fair? Unless YOU were born a pro, most amateurs get a sense of accomplishment and pride that comes from a place next to their name after 50 minutes of racing. It's also nice to follow your progression, seeing a 50th/50 turn into a 5th/50..
You say it's the "race" that matters and not the results, but wtf is a race without results?? Maybe in your world that makes sense but I'd venture to say here on planet earth those aren't mutually exclusive bud.
Points: 33
The result matters, seeing
Submitted by Savage One (not verified) on
The result matters, seeing them online is nice, but... declaring a race as a worthless activity without some lame-ass self esteem boosting act of seeing the results online is frankly pathetic.
Points: 25
BRAC Camera?
Submitted by Your name (not verified) on
Too bad BRAC can't sell off part of the chip timing system and buy a few Go-Pro Cameras for promoters to use. They have $300K in assets, so a thousand bucks for a small camera/monitor system would be nice. Riders paid $2.50 each to BRAC for what? Other states do this for less fees.
Points: 15
The Promoters are responsible for results.
Submitted by Cyclist (not verified) on
Promoters are responsible for results. They can hire top notch race results companies or not.
Without Limits is top notch with Race Rite.
Boulder Cup is so CHEAP that a race that should have chip timing does not.
BRAC supply officials to be the impartial arbiter of sport so these events are true competitions.
On the flip side......
BRAC is also around to help the cycling community. BRAC has to play both sides of the coin.
Each Chief Referee should have a small race kit including a camera, recording device, and playback. Pretty cheap over all.
Points: 40
Randy RULES!
Submitted by Old Man (not verified) on
Thanks to Randy for standing up and reminding everyone what mass start bike is all about. That's doing your best to do your job in the race. If your race revolves around an online result, you are sorely missing the point of racing and I would be surprised to see you racing in 5 years. This concept of place matters over execution and experience in races has been degrading local racing here in CO for a decade. Hearing what people are expecting from a bunch of college kids trying to help get their team to nationals clearly demonstrates this lack of understanding of core fundamentals of the sport.
Good luck to all you results seekers. I mean that. If you can someday grasp the difference between results and accomplishment there is some hope for you long term.
Randy I look forward to seeing you on the start line for years to come.
Points: 56
Submitted by Old Man (not verified) on
The fact people keep voting thumbs down on this furthers my point. The new breed of racer seems to run a computer based life that lacks understanding of the importance of time and experience on the bike. Keep voting it down and showing me that your online world (results) is more important than what you do in a race.
Points: 75
Right on, Old Man. And R.
Submitted by Cooter Brown (not verified) on
Right on, Old Man. And R. Savage. Back in the day, IF you were at a fairly big race, you MIGHT see your name in the printed results in the back of Velonews or Winning magazine, a month or more after the race happened. Wasn't any such thing as online results for at least the first 15 years I raced. These days, I admit I check online results of races I have done in the past and didn't do this year, or check races in areas where I've lived/raced before, just to see how old friends are doing. As for checking online for my results of races I did yesterday, I truly could not give a rat's ass about that. I know how I raced and within a general range, how I placed. The experience is the thing, the online results, meh... not so much.
another old man, different view
Submitted by chris (not verified) on
You are too old to believe everything you think, ie the thumbs down thing proves your point???, nothing wrong with progress, expecting to see results simply means that, in no way does it refer to rule #5, they take a fee, accurate results are part of it, maybe not the most important part of the race, but a part nonetheless, post em in a timely manner, no excuses
Points: 37
Video from yesterday's 3/4 race
Submitted by Stephen Fitzgerald (not verified) on
Points: 34
Any close calls with the ISLANDS??
Submitted by Cyclist (not verified) on
Interesting that this amateur race had road islands. Nice hazard to keep you on your toes and your head up.
Points: 9
Hey Old Man...
Submitted by MJ (not verified) on
I can't wait to join you and Randy at Ride the Rockies, Elephant Rock, Copper Triangle and all of the other wonderful rides where results don't matter. All 3 of us can ride together for the sake of "accomplishment" and not care who wins or gets last place. (note: there is absolutely nothing wrong with this btw)
My point is, r-e-s-u-l-t-s are primarily what distinguish a race from a ride (fundraiser, group ride, solo ride, etc.). Results keep track of the winners and losers. I'm not saying racing is better than riding (I do both) but my expectation is that when I sign up and pay for a race, I expect to see the results. Otherwise, I might as well have joined in the local group ride or even better, participated in a fundraiser ride (again, nothing wrong with either of these).
Also, when I refer to "results" I mean any medium under the sun that shows 1st - last place and everything in between. I could care less if they're online or taped to a brick wall after the race.
I can almost agree with a
Submitted by Cooter Brown (not verified) on
I can almost agree with a couple of your points. Like you, I don't care if results are online or taped to a wall. But, if it's not a series race where it's important to verify my exact placing (assuming I'm in the points) I don't really care if I know exactly where I finished. 22nd vs 24th vs 29th doesn't matter.
I categorically disagree that results are what differentiate between a ride and a race. There are tons of folks out there who treat rides like races and want to see their exact finish time/place for whatever charity ride they just finished. They may even ride those events as if they're racing the other entrants. What differentiates those events from races is not whether you finished in front of someone, but whether that someone is competing against you and the other entrants. I understand people wanting to know how long a ride took for them, but hey, they can time that themselves. To get a finishing place seems silly to me. If the majority of entrants in a ride are just treating it as a ride, it doesn't matter one bit how many people finished in front or behind you. Who cares if you beat someone who wasn't trying to beat you?
Races are different, as you are trying to beat others who are trying to beat you. Now, I realize this sounds like an argument for full race results down to the last finisher, but it's not. As I said above, the exact placing isn't really relevant to me as long as I gave my best effort,and have a general idea as to where I finished (top third, bottom third, whatever...).
Points: 46


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pssst….cynthia rowley eyewear discount & winners.
thank you so much to all the enthusiastic comments and entries for the cynthia rowley eyewear giveaway!! the two lucky winners are christine from heritage & joy and gina from hello there home. congratulations!
and PSSST….there's a READER DISCOUNT: so you guys still win…because cynthia rowley is offering up a reader discount as a thank you for all who...
Read More »
the better to see you with: a giveaway.
• this giveaway post is in partnership with lookmatic.
it's your lucky friday, because lookmatic is giving away another pair of prescription, non-prescription eyeglasses or sunglasses — you get to take your pick! some of us are glamour girls, and may prefer a fun cat eye like the patti goes to paris, and some of us (ahem) are more nerdy, and like a more bookish...
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tuesday's girl: lookmatic eyeglass giveaway.
• this giveaway post is in partnership with lookmatic.
if you've been following the blog here for a while, you probably know by now that i'm a big fan of eyeglasses. that quote from writer dorothy parker, "men seldom make passes at girls who wear glasses"? i don't believe it for one minute. i think glasses look charming on women, and men as...
Read More »
i got some brand new specs! the very lovely folks at 1800specs offered me a pair of new eyeglasses in return for a sponsored review, and well, i was in serious need of some updated glasses, so i said, "why not?". y'all know i don't do a lot whole lot of sponsored posts around here, but this seemed like a no brainer. plus, i freakin' love these...
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tuesday's girl: girls who wear glasses.
i've always been a big fan of writer dorothy parker, and one of her famous quips: "Men seldom make passes at girls who wear glasses." but i kinda don't believe that. there are loads of women who look fantastic in glasses. this tuesday's girl it's all about the girls in glasses.
asos geeky glasses; grace kelly; marilyn monroe; amanda pearl...
Read More »


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More sales to put you in a good mood this weekend! Junk Food Clothing Co has announced its Easter Sale which run from now through April 20th.
Shoppers will score an extra 30% off items on sale! Shop the sale online at www.junkfoodclothing.com using promo code: JFEASTER at checkout.
Happy Shopping!


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The EcoHat is as typical of the Oxley Woods design as an old-fashioned chimney. The unit is easily accessible from inside the home, allowing for repairs and updates to technology without the need for a cherry picker.
The EcoHat's casing conceals its unsightly gadgetry, while still allowing the solar panels to be angled for maximum efficiency. "Sometimes in environmental housing you have to orientate the houses quite vigorously," says Partridge. "This allows for the house to be orientated in any direction, while the EcoHat always points in the appropriate direction for solar efficiency." To that end, the architects claim that the Ecohat-wearing home can offer up to 50 percent reduction in carbon dioxide emissions.Time will tell whether the EcoHat will be the feature that marks a new generation of British homes, but if it becomes half as ubiquitous as the top hat or the bowler once was, then this piece
of rooftop millinery will undoubtedly be declared a resounding success.


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.Club is a new generic top level domain name ("gTLD") that has been issued to .CLUB DOMAINS, LLC., who is the only applicant for the domain after winning a private auction in June 2013. Now, clubs, membership organizations and others are able to buy .Club names such as book.club, yacht.club, OrangeCountyGolf.club or any other name with the .CLUB extension.
ICANN (the Internet Corporation for Assigned Names and Numbers), the organization that issues the .com, .org., .biz, etc., in January 2012 opened the doors for new top level domain names to be applied for. Nearly 2,000 new names were applied for by companies including Google, Amazon, Nike, and others.
According to the ICANN rules, if more than one company applies for the same name, the parties in contention can have a private auction to decide who gets to proceed with their application for the name. .CLUB DOMAINS, LLC was in contention with two other companies, Donuts Inc. and Merchant Law Group. The auction that included .CLUB was the first private auction held for new gTLD's.
In accordance with the auction agreement, no financial information will be released regarding the auction.
.CLUB DOMAINS LLC is a Fort Lauderdale, Florida based company founded by serial entrepreneur Colin Campbell. The company was formed specifically for the purpose of applying for the gTLD ".CLUB" and to operate the .CLUB registry, as well as build an online social platform for clubs and membership organizations.
As many businesses know, it is often difficult to get the domain name you want, or the domain name that truly best represents your business. New generic TLD's will give individuals and companies new flexibility to find a domain name that best suits their needs. In particular, .CLUB provides the ideal domain name opportunity for any group or membership organization, retailers with affinity and loyalty programs, and really, anyone with a passion.
.CLUB was the first "top 20" generic to come to market and is available now!
.Club is not just another new top level domain name. The word "CLUB" is not like any other "generic" string – "Club" brings immediately recognizable meaning and marketing value to any name to the left of the dot. In addition, .Club is a truly global brand – the word "club" carries the same spelling and meaning all over the world.
There are literally millions of clubs and membership organizations throughout the world, but the market for .Club names is much larger than just existing clubs. Every consumer facing business needs a .club name for their affinity/loyalty/customer community. There are over 600 million Facebook groups and countless groups on LinkedIn, Google and Yahoo, many of which are actually clubs, representing people with hobbies and shared interests and passions. Everyone has a passion. Now everyone can have a .CLUB name.
Yes! .CLUB is a completely open registry with no restrictions or validations required to obtain a name. Whether you are an established organization with thousands of members, or an individual with a passion you want to share, there's a .CLUB name for you.


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Jun 30, 2009
Illustration & Animation by Scott K. MacDonald
Scott K. MacDonald (SMAC) is an illustrator/animator living in Vancouver, BC. His style references comic art and street culture. I'm quite partial to the way he represents fashion in his illustrations, he pays attention to intricacies while maintaining the crisp simplicity that permeates his work. Some highlights include the Tyson 85 Book (which I'd love to get my hands on) and the Cold Kids Series.
Via Signalnoise.com


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When the topic of sports-related concussions is brought up, male football players come to mind. However, a new study reported that an alarming number of concussions were occurring among female middle-school soccer players. The study was reported online on January 20 in the journal JAMA Pediatrics by researchers at the University of Washington in Seattle, Washington.
The study authors note that awareness of sports concussion has increased markedly in recent years; however, research on concussions among middle-school athletes is extremely limited. Therefore, they conducted a study to evaluate the frequency and duration of concussions in young female soccer players; in addition, they evaluated whether concussions resulted in the girl quitting the game and seeking medical attention. The study group comprised 351 female soccer players who were members of soccer clubs in the Puget Sound region of Washington State. From March 2008 through May 2012, girls aged 11 to 14 years, from 33 randomly selected soccer teams were evaluated. Among the players contacted, 83.1% participated and 92.4% completed the study.
The investigators measured the number of concussions that occurred during the study period. In addition, they obtained information regarding the number, type, and duration of concussion symptoms. On a weekly basis, they questioned the girls regarding concussion symptoms and, if present, they inquired regarding the symptom type and duration, the event resulting in symptom onset, and whether the girl obtained medical attention or played while the symptoms were present.
The researchers found that, among the 351 soccer players, 59 concussions occurred during 43,742 athletic exposure hours. The cumulative concussion incidence was 13.0% per season; the incidence rate was 1.2 per 1,000 athletic exposure hours. On average, the symptoms lasted for four days. Heading the ball accounted for 30.5% of concussions. Players with the following symptoms took a longer time to recover than girls without these symptoms: light sensitivity (16.0 vs. 3.0 days), emotional lability (mood swings; 15.0 vs. 3.5 days), noise sensitivity (12.0 vs. 3.0 days), memory loss (9.0 vs. 4.0 days, P = .04), nausea (9.0 vs. 3.0 days), and concentration problems (7.0 vs. 2.0 days). The majority of the players (58.6%) continued to play with symptoms; among that group, 44.1% received medical attention.
The authors concluded that concussion rates in young female soccer players are higher than those reported in older age groups; furthermore, most of the girls who suffer a concussion report playing while the symptoms are present. Heading the ball was a frequent cause of concussions among the study group. The noted that, sadly, awareness of recommendations to not play and seek medical attention is lacking for this age group.


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This week marks the passing of poet Maya Angelou. She was especially beloved in the African American community, but her poetry has a universal quality.
It speaks to many who feel trapped and victimized by our society.
One of her most famous poems, "I Know Why the Caged Bird Sings," perfectly captures the feeling of having something to say or contribute to society, but not being allowed to express it.
It describes the feeling of autism. The cage represents the sensory overload in which autistic people are constantly surrounded.
It represents the social barrier that separates them from neurotypical society.
The song is the creativity, intelligence and self-expression, trying to break out of the cage and into the world.
The clipped wings are the social skills that they lack that prevent them from "flying" with the other "birds" in our society.
The tied feet are the side effects that some have with autism; an inability to speak or communicate in a way that others understand.
In the poem, the reader feels the sadness of the bird, yet its song is drowned out by the much louder birds flying and singing in freedom.
The reader knows that this bird is most likely doomed to die in pain, yet the door to the cage can be opened if someone takes the chance to set the bird free.
It is harder to be free with clipped wings, but it is possible with compassion and support.
The bird sings, with every breath he has, to spread the hope that this might happen.
It can. It is hard, it goes against all we have been taught and against tradition, but it can happen.
From this reporter and the autistic community: Thank you Maya Angelou, rest in peace and always "dare to claim the sky."


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Mar 14, 2012 11:15 AM
We never thought we'd prefer someone regard us as a saucy cow instead of a saucy minx, but Cowshed Saucy Cow Softening Conditioner ($25) has changed our minds on that subject. And on the subject of hair care. We've been using the same shampoo and conditioner for about three years now. But after our recent introduction to this bovine betty, we've become believers in the power of the essential oils from lavender and lemon. Now our hair is softer than a baby's bottom. In fact, it's a soft as a cow's udder, which, if you've never touched one, is surprisingly soft.
If you've got a product or service that you'd like to promote on Outblush, click here to find out about our advertising opportunities.
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Daniel Lamont Franks
Position: TE
Height: 6-6 Weight: 263 lbs.
Born: January 6, 1978 in Riverside, CA
High School: Big Spring
College: Miami (FL) (school history) (Franks college stats)
Drafted by the Green Bay Packers in the 1st round (14th overall) of the 2000 NFL Draft.
Weighted Career AV (100-95-...): 19 (5014th overall since 1950)
3-time Pro Bowler (fine print)
Sponsor this page for $10 and help Pro-Football-Reference.com provide this service. Your message will replace this ad.
Output includes all games from 1920 to 2015.


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Blogs are an excellent way for Long Beach writers and authors to promote their work. Here are a few ideas for using your blog to promote your books, articles and business.
Blog about the writing process
Readers love to "get inside the mind" of their favorite writers. So blogging about your process: how you came up with your idea, the research you've conducted, etc., is an excellent way to build your fan base. You can even share some excerpts from your upcoming works. This can get your fan based engaged and works well for both fiction and nonfiction.
Blog about your expertise
Most writers specialize in one to three topics, whether they write fiction or nonfiction. Your readers will find your knowledge interesting, so you can blog about expansions of, or tangential meanderings from, the main topic of your work.
Doing this gets readers interested in the topic and gives them a taste of your writing style. This strategy is excellent for nonfiction authors, but can be modified to work for fiction authors, as well. (For example, if you write hard science fiction, include posts around the research you've done to add verisimilitude to your work. So, if your forthcoming story features a space elevator, share some information about it that doesn't fit in your story, but give readers a greater understanding of what it is.)
Include your blog audience in the formation of your next work
Getting your readers involved with your next work is great way to create engagement. Having trouble deciding what your next character should be named? Ask your readers! Wondering what subtopics should be covered in your next book? Ask your readers! This strategy not only can help you get past writer's blocks, but it also engages your fans, making them feel a part of something bigger.
Blog about events that you'll be attending, are attending or just came back from attending
Let your readers be a fly on the wall of your travels. When you attend events where fans can meet you, such as conventions, trade shows, book signings and more, blog about them and let your readers know. Mention that you'll be attending such-and-such event and provide your readers with information on how they can attend, too. If the event is multi-day, post a daily summary of the experience. And, once you've returned, you can blog about lessons learned or even fun things that happened. This is a great fan community building strategy.
Tip: Include photos from these events and be sure to take a selfie or two. A selfie (a self-photo taken with your camera phone, is a fun, humanizing way to build rapport with your readers, and is easy to share via social media.
Are you an entrepreneurial author? Do you want to be? Are you ready to build your business and platform so that it expresses your creativity, conveys your worth and message authentically and is profitable? Visit www.carmaspence.com to learn more.
NOTE: Are you a writer, author or editor connected to Long Beach in some way? Please contact me ... and you can be a part of my series of profiles of local writers!


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The word of a reboot to Marvel's Fantastic Four has been circling the movie world for sometime. The movie found its director through Chronicles' Josh Trank, and the film is scheduled to hit theaters on June of 2015. It seems like this reboot is ready to go, except there has been one thing missing: the Fantastic Four themselves. While the movie has been in motion, the film has lack its primary cast. That is until today.
The news broke last night and it is official, The Fantastic Four has its team. The cast is as followed: Miles Teller will play Reed Richards/Mr.Fantastic. Kate Mara dawns the role of Susan Storm aka The Invisible Woman. Chronicles' Michael B Jordan will play Johnny Storm, or better known as The Human Torch. Finally, Jamie Bell will play Ben Grimm, otherwise known as The Thing.
As you can see from the casting, the film is taking a different approach for Marvel's First Family as the movie will be featuring a younger Fantastic Four. What this entails for the story is still up in the air, but more details will no doubt be revealed in the months to come.
The Fantastic Four hits theaters on June 19, 2015


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Mar 9, 2011 8:45 AM
If everyone believed the old adage that says if something is too good to be true it probably is, there would be no such thing as the cosmetics industry. But hope (foolishness?) springs eternal! Enter Tarte's new product, Pure Maracuja Oil ($46). According to the company's literature, the oil is extracted from the "pure miracle" fruit, which was discovered in the jungles of the Amazon. Local women harvest the fruit only once a year and extract the oil by hand, which actually makes the $46 price tag seem a little low for all the work that goes into this product. Tarte did its own study and found the oil to create a bunch of amazing results: everything from reduced wrinkles and improved texture to smaller pores and more even skin tone. After 2 weeks of nightly application, our findings are slightly different: fewer dry spots and smoother texture but stubborn red blotches and fine lines remain. For now, this will replace our current night cream but we'll keep an eagle eye out for the true fountain of youth. Which we know is out there somewhere.... Right?
Full disclosure: Outblush received a free sample of this product.
Maracuja is just the Portuguese word for Passion Fruit. These are ubiquitous in Latin America...
Thanx for an honest review. I worry when everything is super wonderful all the time!
So in other words, this oil is not all that they want to say that it is. I have been trying to find reviews from other sources other than qvc and, there are none! I was tempted to try this oil and now I don't think I will after reading here.
I LOVE this product. I had surgery less than one month ago and use this oil nightly. I have noticed less surgical swelling since using this product. My skin looks more radiant than when I was 18. LOVE this stuff!
If you've got a product or service that you'd like to promote on Outblush, click here to find out about our advertising opportunities.
Outblush is a blog for girls who love to shop. Our staff digs up the best clothes, home stuff, beauty items, and more. New items are posted every day — bookmark us and check out:


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This is a stunning Monique Lhuillier "Miranda" ivory French Alencon lace dress with an ivory silk underlay. There is an ever-so-slight mermaid cut and a deep V in front and back. Measurements are 34/27/36 and I wore flats, so the dress is shorter than many, at about 5'5″ with the gorgeous chapel train (and 3-point hook-and-eye bustle). The champagne sash (about 14 feet) is included.
I have such wonderful memories of this dress, and can't tell you how many people have gushed over it!!! I am only selling it because it seems silly to keep it in a box in my closet forever. I'd rather share it with another blushing bride and give her the opportunity to have similar experiences that I had in this breathtaking gown!
Immediately after the wedding weekend in September 2011, the dress was professionally dry cleaned and boxed to be kept in storage. At the request of a potential buyer, I removed it from the box for detailed photos in July 2013. Because it is not a brand new gown, there is minor wear, most notably a snag on the left side under the bust, although it was directly under where I wore the sash. If you choose to wear the sash as well, I would expect the hole to be covered. Either way, I do believe it could be repaired. Please contact me for more detailed photos.
- Label Size: 6
- Street Size: 4
- Bust: 34
- Waist: 27
- Hips: 36
- Height with Shoes: 5'5
- Alterations:
- Color: Ivory
- Silhouette: Mermaid
- Material: Lace, Silk
- Neckline: V-neck
- Style: Belt/Sash, Not white, Open Back
- Condition: Used
- Original Owner: Yes
- Has Original Receipt:
- Preservation Method: Professionally dry cleaned and boxed, but opened for detailed pictures 7/2013.
- Terms of Sale: All Sales Final
- Location: Indianapolis, IN
- Will Ship to: Anywhere at Owner Expense
- Payment Methods Accepted: Escrow.com
Please read our BUYER'S GUIDE before purchasing a dress online.


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Narrow year range (drag arrows to filter):
The new 2015 BMW Alpina B6 xDrive Gran Coupe offers more performance than the 650i xDrive, but more luxury than the M6 Gran Coupe. Alpina, by the way, is a 3rd-party high-performance BMW tuner, working so closely with BMW that its cars are sold in BMW dealerships.
Drivers who love engaging their left foot will rejoice that M6 performance variants can be had with a 6-speed manual transmission in lieu of the 7-speed double-clutch automatic. For just 100 buyers, there is a limited Frozen Brilliant White Edition convertible. All 2014 BMW 6 Series models receive updates to their navigation systems.
New 2013 6 Series Gran Coupes debuted in spring, 2012 offering the same features and powertrains as the coupes and convertibles, and the 650i models' TwinPower turbo V8 is upgraded to 445 horsepower and 480 lb-ft of torque, 45 more horses and 30 more lb-ft than in 2012. The M6 Coupe and Convertible boast BMW's most powerful production engine ever, a 560-hp 4.4-liter TwinPower turbo V8, up five hp with the same 500 lb-ft of torque as the V10 it replaces, and 25 percent more fuel efficient.
The 2012 BMW 6 Series is about as all-new as an all-new model can be. Aside from an overwhelming list of new features and technologies, the 6 Series lineup will now include a 6-cylinder turbo engine option (640i Coupe and 640i Convertible) and available all-wheel drive (650i xDrive Coupe and 650i xDrive Convertible). Later we'll see a high-performance M6 model and a first-ever 4-door 6 Series in the spirit of the Mercedes-Benz CLS and Audi A7.
Save for adding Carbon Black Metallic paint to their exterior color palettes and adding the newest iteration of iDrive, both the 2009 BMW M6 Coupe and Convertible are pure carryover offerings from 2008.
The M6 is derived from the 6 Series and has a revised front end, a more pronounced integrated rear deck spoiler and Active Head Restraints. A heated leather steering wheel and High Beam Assist join the options list.
The 2015 BMW 6 Series slots between the 5 and 7 Series cars with a coupe, a convertible, and a 4-door that BMW calls a "Gran Coupe," but we all know is really just a sleek sedan. Sleekness is all part of the game though, as the 6 Series is designed to offer eye-catching style over practical transportation. All three models offer plenty of style and performance, with engines ranging from a turbocharged 6-cylinder to a couple different V8 models. With roots that trace back to the late 1970s, the 3rd-generation 6 Series remains a leader in grand touring, even against such tough competitors as the Jaguar XK, Mercedes-Benz E-Class Coupe and Audi S5.


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Kevin Jiggetts - The Prince Georgian Magazine October 2007
International Talent, Local Roots
de The Eic Mitchell Publishing Group, LLC.
Kevin Jiggetts
Award winning and critically acclaimed actor / writer Kevin Jiggetts is a sixteen year veteran of the industry. Although local now, he is still represented by one of New York's top literary and legit agencies. His resume' reflects numerous theatre productions, both local and abroad, to include, Joe Turner's Come and Gone / Kennedy Center, Wedding Dance / The Kennedy Center, Fences / Everyman Theatre, Leaving The Summer Land / Theatre J, Anna Lucasta / Rep Stage, and Tripping Through The Car House / Woolly Mammoth Theatre to name a few. In addition, his guest starring role's on T.V. include Law and Order SVU, Homicide (directed by Kathy Bates), The Wire, Miracle's Boys (directed by Spike Lee), America's Most Wanted and The Cosby Show, and starring roles in such films as The Box Preacher, U Need A Ride, Who's Crazy Here (executive produced and directed), The Date, Naked Man, etc. He has two screenplay's currently under strong consideration with several major Hollywood studios. He is a member, in good standing, of SAG (Screen Actor's Guild), AEA (Actor's Equity Association), and AFTRA (American Federation of Television Radio Artists). Oh and we gottem for the cover of The Prince Georgian Magazine.
See www.IMDB.com or www.Google.com Key words...Kevin Jiggetts
Mr Mitchell is a personal product of Prince George's County. Having seen the many changes in his home town he noticed the lack of print and media that exposed the great and wonderful stories rooted in Prince George's County. During a perfect time of growth, empowerment, and success; we are changing what you 'think' you know about Prince George's County and are certainly changing what you are told. A premium social magazine. Recently voted the most sought after magazine representing the good life of Prince George's County. Enjoy.
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Lima Restaurant & Lounge Publicado 06 de marzo de 2009
Rock Newman - The Prince Georgian December 2008 Publicado 06 de febrero de 2009
Lavar Arrington - The Prince Georgian November 2008 Publicado 03 de febrero de 2009
KAS - The Prince Georgian Magazine March 2008 Publicado 12 de mayo de 2008
Ron Wright - The Prince Georgian Magazine January 2008 Publicado 28 de febrero de 2008
Trevor Otts - The Prince Georgian December 2007 Publicado 11 de enero de 2008
Ean Williams - The Prince Georgian November 2007 Publicado 02 de diciembre de 2007
Mike Lyles - The Prince Georgian September 2007 Publicado 23 de septiembre de 2007


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Outgoing Chadian Ambassador to Cameroon, Yoosem-Kontou Noudjiamlao? has told the press that he is a happy man, going back to his country after spending seven years? two months in a country he describes as beautiful. He was speaking on Friday August 8, 2014? after a farewell audience with Prime Minister, Head of Government, Philemon Yang? on behalf of the Head of State, Paul Biya. Yoosem-Kontou Noudjiamlao was Dean of the Diplomatic Corps in Cameroon for well over three years.
Yoosem-Kontou prides himself for having assisted in State visits between Cameroon and his country. President Idriss Deby Itno has been to Cameroon four times during his tenure. He underlined that he is a living testimony of Cameroon's political evolution and the road to being a middle-income economy by 2035 but regretted threats coming Boko Haram insurgency, tarnishing the image of a peaceful country with its loving people. He was however, sure of the dynamism of Cameroonians, saying he was confident that they will surmount the challenges. Cameroon and Chad are not only neighbours but long-time friends and according to Yoosem-Kontou, strategies are being mapped out to counter insecurity.
On bilateral ties between Yaounde and N'Djamena, Yoosem-Kontous said he was proud to speak of it. In recent years both countries have had to share much. Chad transits its petrol through Cameroon; both countries are constructing a link bridge in Kousseri in the Far North, another one in the pipeline from Yagoua still in the same region to Mbongor in Chad, the road between Ngaoundere and Mondou and the railway linking the two countries.


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Skydiving.com now has a network skydiving location serving Charles City and Floyd County in Iowa. Call Skydiving.com at 1-800-617-7948 for details, free information and specials on skydiving in Charles City, IA today!
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Nov 17, 2009 9:30 AM
Whether you need to do a last makeup check before you leave the house or you're still hoping you'll be able to crawl through to an alternate world one of these rainy days (or, for that matter, if you occasionally need to ask whether you're still the fairest in the land, you narcissist you) you'll need to get a mirror. And the rectangular one stuck to the wall above the sink? Boring. Also probably misted over when you really need it. May we suggest the Trevi Mirror ($258)? We like the graceful curves and points of the frame, since they remind us of flowers much more effectively than a heap of carved and painted roses would.
If you've got a product or service that you'd like to promote on Outblush, click here to find out about our advertising opportunities.
Outblush is a blog for girls who love to shop. Our staff digs up the best clothes, home stuff, beauty items, and more. New items are posted every day — bookmark us and check out:


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Price: $11.95
National Geographic's Cyprus Adventure Map is designed to meet the unique needs of adventure travelers with its durability and accurate information. This folded map provides global travelers with the perfect combination of detail and perspective, highlighting hundreds of points of interest and the diverse and unique destinations within the country.
The front side of the Cyprus map shows the western portion of the island. This side details the regions of Paphos, Limassol, Nicosia, Larnaca, and Kyrenia. The reverse side of the map shows the eastern part of the island. This side details the regions of Larnaca, Kyrenia, and Famagusta. The map includes the locations of cities and towns with a user-friendly index, plus a clearly marked road network complete with distances and designations for major highways, main roads, and tracks and trails for those seeking to explore more remote regions. Every Adventure Map is printed on durable synthetic paper, making them waterproof, tear-resistant and toughcapable of withstanding the rigors of international travel.
Key Features:
Adventure Maps provide global travelers with the perfect tool for navigating cityscapes and more remote attractions. Each title contains accurate topography, up-to-date roads, points-of-interest, and detailed inset maps for major cities, plus a host of important travel tips. Adventure Maps are printed on the same durable, waterproof, and environmentally friendly material as our Trails Illustrated maps, making them ideal for the rigors of international travel.


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Within each category of event professionals, there are always a number of subcategories just to make planning more confusing because many professionals realize they have a specific strength that fits more accurately into a niche market. One such area: event planners and event designers. Both professionals are very different even though they sound similar, and […]Read More
Wedding Designers
Today is a special Thursday! It's special because Thursday Tips is now a series that other bloggers and wedding professionals are taking part in. It's starting out small so far, but I'm hoping it will grow to include many others in the wedding industry who want to share tips and advice with all of you […]Read More


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Apr 23, 2013, 02.17 PM | Source: Moneycontrol.com
Kotak Institutional Equities raised its target price on Mindtree to Rs 900 from 850, saying the stock offered good medium-term opportunity.
Kotak Institutional Equities raised its target price on Mindtree to Rs 900 from 850, saying the stock offered good medium-term opportunity.
The mid-tier software services exporter on Monday reported fourth quarter results . Quarterly net profit was down 20 percent quarter-on-quarter (up 14 percent year-on-year) to Rs 79 crore and revenue rose 4 percent sequentially (17 percent YoY) to Rs 612 crore.
The stock ended down more than 2 percent and further slipped over 2 percent on Tuesday. The street may have given it a thumbs down, analysts say results were largely in line with expectations and still sound bullish, despite the 56 percent surge in the stock price in the last one year.
"The stock is a good medium-term bet, courtesy significant improvement in profile of client base and account management, consistency in delivery and execution and inexpensive valuations," Kotak said, advising investors "add" the stock.
Citigroup Global Markets maintained a "buy" on Mindtree, although it has slightly reduced its target price to Rs 1,010 from Rs 1,045.
Valuations at 9.3 times one year forward EPS (earnings per share) still look reasonable, it says. However, it has high leverage to discretionary spends and so a recovery here is key, it warns.
Religare Institutional Research, meanwhile, advises a "hold" on the stock.
"Given the lack of further margin triggers and limited acceleration in growth rates, we see limited scope for further earnings upgrades," it said, maintaining a target price of Rs 870 on the stock.
At 10:15hrs, Mindtree was down 1.6 percent at 836.55 on NSE.
Nachiket Kelkar
Mindtree stock price
On June 24, 2016, Mindtree closed at Rs 657.10, down Rs 1.7, or 0.26 percent. The 52-week high of the share was Rs 1607.00 and the 52-week low was Rs 601.25.
The company's trailing 12-month (TTM) EPS was at Rs 36.04 per share as per the quarter ended March 2016. The stock's price-to-earnings (P/E) ratio was 18.23. The latest book value of the company is Rs 143.98 per share. At current value, the price-to-book value of the company is 4.56.
Prakash Gaba of prakashgaba.com is of the view tha
Parag Thakkar of HDFC Securities is of the view th
MindTree Ltd has informed BSE that the 17th Annual
Mindtree Ltd has informed BSE regarding Outcome of
Sandeep Wagle of powermywealth.com recommends exit
After Tamil Nadu issued a notification bringing IT


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Freshman Lana Spitler
Sept. 20, 2013
HIGH POINT, N.C. – Playing in its fourth overtime game of the season, the East Carolina women's soccer team was defeated, 1-0, Friday evening at High Point University.
"I think the team is working hard," said head coach Rob Donnenwirth. "I think we're right there in all of our games and now we need to find ways and make plays. They were really good in the air and caused some problems for us with their height."
After two halves and one 10-minute overtime period did not decide a winner, High Point (2-5) scored on a header by Sarah Sermonet off a Brooke Lisson corner kick just four minutes into the second overtime to give the Panthers the victory.
While field conditions were wet, East Carolina (3-4-2) and High Point fought through a physical first half that saw the Pirates hold a 5-4 advantage in shots, while recording two shots on goal. ECU also owned a 3-0 edge in corner kick opportunities, but the scored stood at 0-0 after the first 45 minutes of play. The scoreless first period was the sixth of the season for East Carolina in its ninth match of the season.
The second half saw the Pirates and Panthers exchange very good scoring chances, but both goalkeepers came up big to keep the game scoreless at the end of regulation. Junior goalkeeper Saundra Baron made four big saves in the period to keep High Point off the scoreboard.
"Saundra is definitely a presence in the goal," Donnenwirth said. "She's a good leader as well. She has the ability to make big saves. For us, [taking] 10 corner kicks is something we need to take advantage of."
Both teams recorded 12 shots in the first 90 minutes, while East Carolina owned a 6-4 edge in shots on goal and a 9-4 advantage in corner-kick opportunities.
Freshman Kelsey Reeves led the Pirates with three shots on the evening, while redshirt junior Lexi Miller, junior Kelly Miller and newcomer Caitlin Hite took two shots apiece in the contest.
East Carolina will take a short break before opening its Conference USA schedule next Friday, Sept. 27, when it hosts Colorado College at 7 p.m. The Pirates will then face off against Charlotte on Sunday, Sept. 29 at 2 p.m. Both matches will take place at the ECU Soccer Stadium.
"I feel like we've been in every game and now we need to get a little hungrier and finish the chances that we have," Donneiwirth said. "We're excited to get into conference play."


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Ben Tate is one of the top remaining running backs left in the free agency market. Tate is coming off of his rookie contract from Houston, where he has been sitting on the bench behind Arian Foster. Tate has shown flashes of talent, including last season when Foster went down with an injury and Tate started the rest of the season. Tate is looking for a team to take a chance on him and give him that big contract that he thinks he deserves.
The Cleveland Browns are a team that is looking for a new running back for next season and a front-runner in signing Tate. The Browns' running back position last season was turned upside when the Browns traded Trent Richardson to the Colts. After the trade, the Browns went through multiple running backs including McGahee, Whittaker, and ended with Edwin Baker. The Browns could make a splash in the free agency market or draft a rookie like Carlos Hyde.
Tate has been in Cleveland since Thursday night with the Browns' organization. With no news coming out of the meetings yet, things could be either going great or the groups are still trying to make a deal that is best for both teams. Last night, Tate shot a picture of Tower City. Hopefully they can make the deal happen over the weekend.
The 5'11", 217-pound running back out of Auburn hasn't played a full season, but each year has averaged over 4 yards a carry all three years he has been in the league. He would be a perfect back for the blocking scheme that Kyle Shanahan is bringing in. Tate would be just one of the offensive upgrades in the offensive, as the Browns are looking at the quarterback and wide receiver positions.
The Browns have made huge moves already in free agency, especially on defense. The Browns signed Donte Whitner and Karlos Dansby on Tuesday and special teams cornerback Isaiah Trufant. Tate would be the second signing for the offensive side after the Browns signed tight end, Jim Dray yesterday and are waiting for Cincinnati to not match the offer on restricted free agent, Andre Hawkins.
Look for the Browns to make some more moves considering they have one of the biggest cap space in the NFL. The Browns have been reportedly looking at players such as Julian Edelman, Emmanuel Sanders, and Ben Tate. The Browns are making moves at turning around the sinking ship. The Browns will also have a chance to make a change in the draft with two first round picks, one second round pick, and two third round picks.


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Whitechapel has unleashed their sixth full-length, 'Mark of the Blade', today worldwide via Metal Blade Records! In conjunction with Mark of the Blade's release, Whitechapel has launched a new video for the album track 'Elitist Ones'.Read More
Downfall of Gaia
German extreme metallers Downfall of Gaia have just entered the studio to record their fourth full-length album and follow-up to 2014's acclaimed 'Aeon Unveils the Thrones of Decay'.Read More
Armored Saint
Following their upcoming summer/fall tour dates, the mighty Armored Saint will head back out on the road this November/December as direct support to Queensryche! Midnight Eternal will also join this USA trek.Read More
On July 22nd, Revocation will release 'Great Is Our Sin.' Today, the band has unleashed a third blistering track from the album - check out the lyric video for 'Crumbling Imperium' now via Loudwire.comRead More
Hammers of Misfortune
On July 22nd, Hammers of Misfortune will release their sixth full-length, 'Dead Revolution.' In anticipation of this release, the band has now launched a new track, 'Sea of Heroes', today via Stereogum.comRead More
Denner / Shermann
Denner / Shermann has released a new video for the track 'Son of Satan', taken from their upcoming album, 'Masters of Evil', out June 24th. To watch 'Son of Satan', please visit metalblade.com/dennershermannRead More
Necromancing the Stone
If flaccid, identikit, breakdown-laden 'metal' is the disease, Necromancing the Stone is the cure. With their upcoming debut full-length, 'Jewel of the Vile', the group plans to vanquish 'Breakdownicus Gratuitous.'Read More
If These Trees Could Talk
If These Trees Could Talk has announced a USA headlining tour in support of their new album, 'The Bones of a Dying World'! Kicking off in August in NY, the trek also features Driftoff, Spotlights, and Alexander Turnquist as support.Read More
New Releases
New Releases
Latest News
Denner / Shermann to release full-length album, 'Masters of Evil', on June 24th via Metal Blade Records
- May 5th, 2016 – First single, "Angel's Blood", now...Read More
If These Trees Could Talk premieres new track, "Earth Crawler", via MetalInsider.net
- May 5th, 2016 – On June 3rd, Akron, Ohio's If These Trees Could...Read More
Jim Breuer and the Loud & Rowdy releases new video for "Thrash" via Loudwire.com
- May 5th, 2016 – Comedian Jim Breuer threw a metal show in his garage...Read More
Rivers of Nihil announce North American tour with Beyond Creation, The Zenith Passage
- May 4th, 2016 – This July, Rivers of Nihil will embark on another...Read More
MetalSucks.net reveals line-up for metallic-hardcore trio Poison Headache
- May 3rd, 2016 – Premieres new track, "Conspirator"; album...Read More
Shai Hulud plot US and Canadian dates beginning May 28
- May 3rd, 2016 – Shai Hulud are currently in Europe in support of...Read More
Abnormality streams new album, 'Mechanisms of Omniscience', via RevolverMag.com
- April 29th, 2016 – 'Mechanisms of Omniscience' out now...Read More
Poison Headache streams first single, "Sin Eater", via Noisey.Vice.com
- April 28th, 2016 – Signs worldwide deal with Metal Blade...Read More


text:
Curative Surgery removes the cancerous tumor or growth from the body. Surgeons use curative surgery when the cancerous tumor is localized to a specific area of the body. This type of treatment is often considered the primary treatment. However, other types of cancer treatments, such as radiation, may be used before or after the surgery.
Preventive Surgery is used to remove tissue that does not contain cancerous cells, but may develop into a malignant tumor. For example, polyps in the colon may be considered precancerous tissue and preventative surgery may be performed to remove them.
Diagnostic Surgery helps to determine whether cells are cancerous. Diagnostic surgery is used to remove a tissue sample for testing and evaluation (in a laboratory by a pathologist). The tissue samples help to confirm a diagnosis, identify the type of cancer, or determine the stage of the cancer.
Staging Surgery works to uncover the extent of cancer, or the extent of the disease in the body. Laparoscopy (a viewing tube with a lens or camera is inserted through a small incision to examine the inside of the body and to remove tissue samples) is an example of a surgical staging procedure.
Debulking Surgery removes a portion, though not all, of a cancerous tumor. It is used in certain situations when removing an entire tumor may cause damage to an organ or the body. Other types of cancer treatment, such as chemotherapy and radiation, may be used after debulking surgery is performed.
Palliative Surgery is used to treat cancer at advanced stages. It does not work to cure cancer, but to relieve discomfort or to correct other problems cancer or cancer treatment may have created.
Supportive Surgery is similar to palliative surgery because it does not work to cure cancer. Instead, it helps other cancer treatments work effectively. An example of supportive surgery is the insertion of a catheter to help with chemotherapy.
Restorative Surgery is sometimes used as a follow-up to curative or other surgeries to change or restore a person's appearance or the function of a body part. For example, women with breast cancer sometimes need breast reconstruction surgery to restore the physical shape of the affected breast(s). Curative surgery for oral cancer can cause a change in the shape and appearance of a person's mouth. Restorative surgery may be performed to address these effects.
Cryosurgery technique uses extremely cold temperatures to kill cancer cells. Cryosurgery is used most often with skin cancer and cervical cancer. Depending on whether the tumor is inside or outside the body, liquid nitrogen is placed on the skin or in an instrument called a cryoprobe (which is inserted into the body so that it touches the tumor). Cryosurgery is being evaluated as a surgical treatment for several types of cancers.
Laser Surgery uses beams of light energy instead of instruments to remove very small cancers (without damaging surrounding tissue), to shrink or destroy tumors, or to activate drugs to kill cancer cells. Laser surgery is a very precise procedure that can be used to treat areas of the body that are difficult to reach including the skin, cervix, rectum, and larynx.
Skin cancer and oral cancer are sometimes treated with electrosurgery. This technique uses electrical current to kill cancer cells.
Microscopically Controlled Surgery
This surgery is useful when cancer affects delicate parts of the body, such as the eye. Layers of skin are removed and examined microscopically until cancerous cells cannot be detected.
The term LASER stands for "Light Amplification by the Stimulated Emission of Radiation." Laser light is concentrated so that it makes a very powerful and precise tool. Laser therapy uses light to treat cancer cells. Consider the following additional information regarding laser therapy:
Carbon Dioxide (CO2) Lasers can remove a very thin layer of tissue from the surface of the skin without removing deeper layers. The CO2 laser may be used to remove skin cancers and some precancerous cells.
Neodymium:yttrium-Aluminum-garnet (Nd:YAG) Lasers can penetrate deeper into tissue and can cause blood to clot quickly. The laser light can be carried through optical fibers to reach less accessible internal parts of the body. For example, the Nd:YAG laser can be used to treat throat cancer.
Laser-Induced Interstitial Thermotherapy (LITT) uses lasers to heat certain areas of the body. The lasers are directed to areas between organs (interstitial areas) that are near a tumor. The heat from the laser increases the temperature of the tumor, thereby shrinking, damaging, or destroying the cancer cells.
Argon Lasers pass only through superficial layers of tissue such as skin. Photodynamic therapy (PDT) uses argon laser light to activate chemicals in the cancer cells.
Photodynamic Therapy
Because cancer cells can be selectively destroyed while most healthy cells are spared, photodynamic therapy (PDT) is useful for the treatment of certain cancer tumors. Photodynamic therapy (also called photoradiation therapy or photochemotherapy) is a treatment that uses a combination of a light source and a photosensitizing agent (a medication that is activated by light). The photosensitizing agent collects more in cancer cells than in normal cells. When the laser's light is focused directly on the tumor, the cancer cells absorb the light, and a chemical reaction occurs which destroys the cancer cells.
Chemotherapy is the use of anticancer drugs to treat cancerous cells. Chemotherapy has been used for many years and is one of the most common treatments for cancer. In most cases, chemotherapy works by interfering with the cancer cell's ability to grow or reproduce. Different groups of drugs work in different ways to fight cancer cells. Chemotherapy may be used alone for some types of cancer or in combination with other treatments such as radiation or surgery. Often, a combination of chemotherapy drugs is used to fight a specific cancer. Certain chemotherapy drugs may be given in a specific order depending on the type of cancer it is being used to treat.
There are over 50 chemotherapy drugs that are commonly used. The following table gives examples of some chemotherapy drugs and their various names. It lists some of the cancer types but not necessarily all of the cancers for which they are used, and describes various side effects. Side effects may occur just after treatment (days or weeks) or they may occur later (months or years) after the chemotherapy has been given. The side effects listed below do not comprise an all-inclusive list. Other side effects are possible.
As each person's individual medical profile and diagnosis is different, so is his/her reaction to treatment. Side effects may be severe, mild, or absent. Be sure to discuss with your cancer care team any/all possible side effects of treatment before the treatment begins.
|Chemotherapy Drug
|Possible Side Effects
(Not all side effects are listed. Some of those listed may be short-term side effects; others are long-term side effects.)
Imatinib mesylate
Side Effects
The side effects of chemotherapy depend on the type of chemotherapy and the amount given. Anticipating and managing side effects can help to minimize them and provide the best possible experience for the person receiving chemotherapy.
Hormones are chemicals produced by glands, such as the ovaries and testicles. Hormones help some types of cancer cells to grow, such as breast cancer and prostate cancer. In other cases, hormones can kill cancer cells, make cancer cells grow more slowly, or stop them from growing. Hormone therapy as a cancer treatment may involve taking medications that interfere with the activity of the hormone or stop the production of the hormones. Hormone therapy may involve surgically removing a gland that is producing the hormones.
How does hormone therapy work
Your physician may recommend a hormone receptor test to help determine treatment options and to help learn more about the tumor. This test can help to predict whether the cancer cells are sensitive to hormones.
The hormone receptor test measures the amount of certain proteins (called hormone receptors) in cancer tissue. Hormones (such as estrogen and progesterone that naturally occur in the body) can attach to these proteins. If the test is positive, it is indicating that the hormone is probably helping the cancer cells to grow. In this case, hormone therapy may be given to block the way the hormone works and help keep the hormone away from the cancer cells (hormone receptors). If the test is negative, the hormone does not affect the growth of the cancer cells, and other effective cancer treatments may be given. Always discuss the results of the hormone receptor test with your physician.
If the test indicates that the hormones are affecting your cancer, the cancer may be treated in one of following ways:
The type of hormone therapy a person receives depends upon many factors, such as the type and size of the tumor, the age of the person, the presence of hormone receptors on the tumor, and other factors.
When is hormone therapy given
Your physician may prescribe hormone therapies before some cancer treatments or after other cancer treatments. If hormone therapy is given before the primary treatment, it is called neoadjuvant treatment. Neoadjuvant treatments help to kill cancer cells and contribute to the effectiveness of the primary therapy. If hormone therapy is given after the primary cancer treatment, it is called adjuvant treatment. Adjuvant therapy is given to improve the chance of a cure.
With some cancers, patients may be given hormone therapy as soon as cancer is diagnosed, and before any other treatment. It may shrink a tumor or it may halt the advance of the disease. And in some cancer, such as prostate cancer, it is helpful in alleviating the painful and distressing symptoms of advanced disease. The National Cancer Institute (NCI) states that although hormone therapy cannot cure prostate cancer, it will usually shrink or halt the advance of disease, often for years.
What medications are used for hormone therapy
Hormone therapy may be used to prevent the growth, spread, and recurrence of breast cancer. The female hormone estrogen can increase the growth of breast cancer cells in some women. An example of this type of medication is tamoxifen (Nolvadex®), which works by blocking the effects of estrogen on the growth of malignant cells in breast tissue. However, tamoxifen does not stop the production of estrogen. Men who have breast cancer may also be treated with tamoxifen.
Tamoxifen is currently being studied as a hormone therapy for treatment of other types of cancer. There are several other hormonal agents for breast cancer that work like tamoxifen, including raloxifene (Evista®), toremifene (Fareston®), and fulvestrant (Faslodex®).
Hormone therapy may be considered for women whose breast cancers test positive for estrogen and progesterone receptors.
Newer medications approved by the US Food and Drug Administration (FDA), called aromatase inhibitors, are used to treat advanced breast cancer or to prevent the recurrence of breast cancer in postmenopausal women. These drugs, such as anastrozole (Arimidex®), letrozole (Femara®), and exemestane (Aromasin®), prevent estrogen production.
Another new drug for recurrent breast cancer is fulvestrant (Faslodex®). Also approved by the FDA, this drug binds with the estrogen receptor and eliminates it, rather than than just blocking it, making it less effective in promoting growth of the cancer. Side effects for fulvestrant include hot flashes, mild nausea, and fatigue.
With prostate cancer, there may be a variety of medications used in hormone therapy. Male hormones, such as testosterone, stimulate prostate cancer to grow. Hormone therapy is given to help stop hormone production and to block the activity of the male hormones. Hormone therapy can cause a tumor to shrink and the prostate-specific antigen (PSA) levels to decrease.
What are the side effects of hormone therapy
The following are some potential side effects that may occur with hormone therapy. However, the side effects will vary depending upon the type of hormone therapy that is given. Every person's hormone treatment experience is different and not every person will experience the same side effects. Discuss the potential side effects of your hormone therapy with you physician.
As each person's individual medical profile and diagnosis is different, so is his/her reaction to treatment. Side effects may be severe, mild, or absent. Be sure to discuss with your cancer care team any/all possible side effects of treatment before the treatment begins.
For prostate cancer, either the surgical removal of the testes or hormone drug therapy can improve the cancer. Both surgery and drugs may cause the following side effects:
For breast cancer, some women may experience side effects from tamoxifen that are similar to the symptoms some women experience in menopause. Other women do not experience any side effects when taking tamoxifen. The following are some of the side effects that may occur when taking tamoxifen:
Taking tamoxifen also increases the risk of endometrial cancer (involves the lining of the uterus) and uterine sarcoma (involves the muscular wall of the uterus), both cancers of the uterus. There is also a very small risk of blood clots and stroke, eye problems such as cataracts, and liver toxicities. Tamoxifen should be avoided during pregnancy.
Tamoxifen is used to treat men with breast cancer as well. As each person's individual medical profile and diagnosis is different, so is his/her reaction to treatment. Side effects may be severe, mild, or absent. Be sure to discuss with your cancer care team any/all possible side effects of treatment before the treatment begins.
Men may experience the following side effects:
Biological therapy (also called immunotherapy, biological response modifier therapy, or biotherapy) uses the body's immune system to fight cancer. The cells, antibodies, and organs of the immune system work to protect and defend the body against foreign invaders, such as bacteria or viruses. Physicians and researchers have found that the immune system might also be able to both determine the difference between healthy cells and cancer cells in the body, and to eliminate the cancer cells.
How does the immune system fight cancer
Biological therapies are designed to boost the immune system, either directly or indirectly, by assisting in the following:
The immune system includes different types of white blood cells - each with a different way to fight against foreign or diseased cells, including cancer:
These types of white blood cells - B cells, T cells, natural killer cells, and monocytes - are in the blood and thus circulate to every part of the body, providing protection from cancer and other diseases. Cells secrete two types of substances: antibodies and cytokines. Antibodies respond to (harmful) substances that they recognize, called antigens. Specific (helpful) antibodies match specific (foreign) antigens by locking together. Cytokines are proteins produced by some immune system cells and can directly attack cancer cells. Cytokines are "messengers" that "communicate" with other cells.
What are the different types of biological therapies?
There are many different types of biological therapies used in cancer treatment.
Biological response modifiers (BRMs) change the way the body's defenses interact with cancer cells. BRMs are produced in a laboratory and given to patients to:
BRMs include nonspecific immunomodulating agents, interferons, interleukins, colony-stimulating factors, monoclonal antibodies, cytokine therapy, and vaccines:
Nonspecific immunomodulating agents are biological therapy drugs that stimulate the immune system, causing it to produce more cytokines and antibodies to help fight cancer and infections in the body. Fighting infection is important for a person with cancer.
Interferons (IFN) are a type of biological response modifier that naturally occurs in the body. They are also produced in the laboratory and given to cancer patients in biological therapy. They have been shown to improve the way a cancer patient's immune system acts against cancer cells. Interferons may work directly on cancer cells to slow their growth, or they may cause cancer cells to change into cells with more normal behavior. Some interferons may also stimulate natural killer cells (NK) cells, T cells, and macrophages - types of white blood cells in the bloodstream that help to fight cancer cells.
Interleukins (IL) stimulate the growth and activity of many immune cells. They are proteins (cytokines) that occur naturally in the body, but can also be made in the laboratory. Some interleukins stimulate the growth and activity of immune cells, such as lymphocytes, which work to destroy cancer cells.
Colony-stimulating factors (CSFs) are proteins given to patients to encourage stem cells within the bone marrow to produce more blood cells. The body constantly needs new white blood cells, red blood cells, and platelets, especially when cancer is present. CSFs are given, along with chemotherapy, to help boost the immune system. When cancer patients receive chemotherapy, the bone marrow's ability to produce new blood cells is suppressed, making patients more prone to developing infections. Parts of the immune system cannot function without blood cells, thus colony-stimulating factors encourage the bone marrow stem cells to produce white blood cells, platelets, and red blood cells. With proper cell production, other cancer treatments can continue enabling patients to safely receive higher doses of chemotherapy.
Monoclonal antibodies are agents, produced in the laboratory, that bind to cancer cells. When cancer-destroying agents are introduced into the body, they seek out the antibodies and kill the cancer cells. Monoclonal antibody agents do not destroy healthy cells.
Examples of monoclonal antibody therapy include trastuzumab (Herceptin®) for breast cancer and rituximab (Rituxan®) for lymphoma.
Cytokine therapy uses proteins (cytokines) to help your immune system recognize and destroy those cells that are cancerous. Cytokines are produced naturally in the body by the immune system, but can also be produced in the laboratory. This therapy is used with advanced melanoma and with adjuvant therapy (therapy given after or in addition to the primary cancer treatment). Cytokine therapy reaches all parts of the body to kill cancer cells and prevent tumors from growing.
Vaccine therapy is still an experimental biological therapy. The benefit of vaccine therapy has not yet been proven. With infectious diseases, vaccines are given before the disease develops. Cancer vaccines, however, are given after the disease develops, when the tumor is small. Scientists are testing the value of vaccines for melanoma and other cancers. Sometimes, vaccines are combined with other therapies such as cytokine therapy.
Are there side effects of biological therapies
As each person's individual medical profile and diagnosis is different, so is his/her reaction to treatment. Side effects may be severe, mild, or absent. Be sure to discuss with your cancer care team any/all possible side effects of treatment before the treatment begins.
Side effects of biological therapy, which often mimic flu-like symptoms, vary according to the type of therapy given and may include the following:
Specifically, cytokine therapy often causes fever, chills, aches, and fatigue. Other side effects include a rash or swelling at the injection site. Therapy can cause fatigue and bone pain and may affect blood pressure and the heart.
Bone marrow transplantation (BMT) is a special therapy for patients with cancer or other diseases which affect the bone marrow. A bone marrow transplant involves taking cells that are normally found in the bone marrow (stem cells), filtering those cells, and giving them back either to the patient or to another person. The goal of BMT is to transfuse healthy bone marrow cells into a person after their own unhealthy bone marrow has been eliminated.
Bone marrow transplantation has been used successfully to treat diseases such as leukemias, lymphomas, aplastic anemia, immune deficiency disorders, and some solid tumor cancers since 1968.
What is bone marrow
Bone marrow is the soft, spongy tissue found inside bones. It is the medium for development and storage of about 95 percent of the body's blood cells.
The blood cells that produce other blood cells are called stem cells. The most primitive of the stem cells is called the pluripotent stem cell, which is different than other blood cells with regards to the following properties:
It is the stem cells that are needed in bone marrow transplantation.
Why is a bone marrow transplant needed
The goal of a bone marrow transplant is to cure many diseases and types of cancer. When a person's bone marrow has been damaged or destroyed due to a disease or intense treatments of radiation or chemotherapy for cancer, a marrow transplant may be needed.
A bone marrow transplant can be used to:
The risks and benefits must be weighed in a thorough discussion with your physician and physicians that specialize in bone marrow transplants prior to procedure.
What are some diseases that may benefit from bone marrow transplantation
The following diseases are the ones that most commonly benefit from bone marrow transplantation:
However, patients experience diseases differently, and bone marrow transplantation may not be appropriate for everyone who suffers from these diseases.
What are the different types of bone marrow transplants
There are different types of bone marrow transplants depending on who the donor is. The different types of bone marrow transplant include the following:
Matching involves typing human leukocyte antigen (HLA) tissue. The antigens on the surface of these special white blood cells determine the genetic make-up of a person's immune system. There are at least 100 HLA antigens, however, it is believed that there are a few major antigens that determine whether a donor and recipient match. The others are considered "minor" and their effect on a successful transplant is not as well defined.
Medical research is still investigating the role all antigens play in the process of a bone marrow transplant. The more antigens that match, the better the engraftment of donated marrow. Engraftment of the stem cells occurs when the donated cells make their way to the marrow and begin reproducing new blood cells.
The bone marrow transplant team
The group of specialists involved in the care of patients going through transplant is often referred to as the "transplant team." All individuals work together to provide the best chance for a successful transplant. The team consists of the following:
An extensive evaluation is completed by the bone marrow transplant team. The decision for you to undergo a bone marrow transplant will be based on many factors, including the following:
Preparation for the recipient
For a patient receiving the transplant, the following will occur in advance of the procedure:
The bone marrow transplant procedure
The preparations for a bone marrow transplant vary depending on the type of transplant, the disease requiring transplant, and your tolerance for certain medications. Consider the following:
The days before transplant are counted as minus days. The day of transplant is considered day zero. Engraftment and recovery following the transplant are counted as plus days. For example, a patient may enter the hospital on day -8 for preparative regimen. The day of transplant is numbered zero. Days +1, +2, etc., will follow. There are specific events, complications, and risks associated with each day before, during, and after transplant. The days are numbered to help the patient and family understand where they are in terms of risks and discharge planning.
During infusion of bone marrow, the patient may experience the following:
After infusion, the patient may:
After leaving the hospital, the recovery process continues for several months or longer, during which time the patient cannot return to work or many previously enjoyed activities. The patient must also make frequent follow-up visits to the hospital or physician's office.
Engraftment of the stem cells occurs when the donated cells make their way to the marrow and begin reproducing new blood cells. Depending on the type of transplant and the disease being treated, engraftment usually occurs around day +15 or +30. Blood counts will be performed frequently during the days following transplant to evaluate initiation and progress of engraftment. Platelets are generally the last blood cell to recover.
Engraftment can be delayed because of infection, medications, low donated stem cell count, or graft failure. Although the new bone marrow may begin making cells in the first 30 days following transplant, it may take months, even years, for the entire immune system to fully recover.
How are the stem cells collected?
A bone marrow transplant is done by transferring stem cells from one person to another. Stem cells can either be collected from the circulating cells in the blood (the peripheral system) or from the bone marrow.
Peripheral blood stem cells (PBSCs) are collected by apheresis, a process in which the donor is connected to a special cell separation machine via a needle inserted in the vein. Blood is taken from one vein and is circulated though the machine which removes the stem cells and returns the remaining blood and plasma back to the donor through another needle inserted into the opposite arm. Several sessions may be required to collect enough stem cells to ensure a chance of successful engraftment in the recipient.
A medication may be given to the donor for about one week prior to apheresis that will stimulate the bone marrow to increase production of new stem cells. These new stem cells will be released from the marrow and into the circulating or peripheral blood system.
Bone marrow harvesting involves collecting stem cells with a needle placed into the soft center of the bone, the marrow. Most sites used for bone marrow harvesting are located in the hip bones and the sternum. The procedure takes place in the operating room. The donor will be anesthetized during the harvest and will not feel the needle. In recovery, the donor may experience some pain in the areas where the needle was inserted.
If the donor is the person him/herself, it is called an autologous bone marrow transplant. If an autologous transplant is planned, previously collected stem cells, from either peripheral (apheresis) or harvest, are counted, screened, and ready to infuse
What complications and side effects may occur following BMT
Complications may vary, depending on the following:
The following are complications that may occur with a bone marrow transplantation. However, each individual may experience symptoms differently. These complications may also occur alone, or in combination:
Long-term outlook for a bone marrow transplantation
Prognosis greatly depends on the following:
As with any procedure, such as bone marrow transplant, prognosis, and long-term survival can vary greatly from person to person. The number of transplants occurring for an increased number of diseases and medical developments has greatly improved the outcome for bone marrow transplant in children and adults. Continuous follow-up care is essential for the patient following a bone marrow transplant. New methods to improve treatment and to decrease complications and side effects of a bone marrow transplant are continually being discovered.
Hyperthermia is heat therapy. Heat has been used for hundreds of years as therapy. According to the National Cancer Institute (NCI), scientists believe that heat may help shrink tumors by damaging cells or depriving them of the substances they need to live. There are research studies underway to determine the use and effectiveness of hyperthermia in cancer treatment.
Heat can be applied to a very small area or to an organ or limb. Hyperthermia is usually used with chemotherapy, radiation therapy, and other treatment therapies. The types of hyperthermia are described in the following chart:
|Type of Hyperthermia
|Treatment Area
|Method of Application
|local hyperthermia
|Treatment area includes a tumor or other small area.
|regional hyperthermia
|An organ or a limb is treated.
|whole body hyperthermia
|The whole body is treated when cancer has spread.
Are there any side effects
There are no known complications of hyperthermia. Side effects may include skin discomfort or local pain. Hyperthermia can also cause blisters and occasionally burns but generally these heal quickly.