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The summary below is from the full report titled "Topical Treatment of Pressure Ulcers with Nerve Growth Factor. A Randomized Clinical Trial." It is in the 21 October 2003 issue of Annals of Internal Medicine (volume 139, pages 635-641). The authors are F. Landi, L. Aloe, A. Russo, M. Cesari, G. Onder, S. Bonini, P.U. Carbonin, and R. Bernabei.
When patients are immobilized in bed, friction between the skin and the bed covers may damage the skin, particularly at contact points where there is a bony prominence like the anklebone or heel. Damaged skin may break down, forming an open sore (pressure ulcer). As pressure ulcers develop, they often lead to infections of the soft tissues and bones, complicating care and prolonging hospitalization. Pressure ulcers are difficult to treat. Until recently, the only treatments available were local wound care (such as washing the ulcer with salt water or applying cleaning enzymes and protective coatings) or surgery. Recently, researchers have found that certain tissues of the body produce substances that promote healing by stimulating the growth of cells to replace those that have been damaged or lost. The first of these stimulating substances to be discovered was called nerve growth factor because it caused nerve cells to grow into damaged tissues. When researchers studied nerve growth factor further, they found that it also stimulated skin cells and other cells that helped repair damaged tissue.
To find out whether applying nerve growth factor to pressure ulcers could speed the healing process.
36 nursing home patients with pressure ulcers of the foot.
The size and severity of each patient's pressure ulcer were measured before the patients entered the study. Patients were then divided into 2 groups of 18 patients each. Group assignments were made by chance so that one group was unlikely to differ in any important way from the other. Both groups received standard local wound care. Patients in one group (the treatment group) were also treated with nerve growth factor that was dissolved in salt water and dripped onto the surface of the ulcer every day. The other group (the control group) had only salt water dripped onto the ulcer. Neither the patients nor the doctors knew which liquid was being applied. The size and severity of the ulcers were reevaluated weekly for the next 6 weeks.
After 6 weeks, the treatment group showed significantly faster healing of the ulcers than the control group. Pressure ulcers healed completely in 8 patients in the treatment group and in only 1 patient in the control group.
None of the patients had diabetes or blood vessel disease, both of which are common in patients with pressure ulcers, so the researchers could not evaluate the effectiveness of nerve growth factor in patients with these complications.
Use of nerve growth factor may represent a significant advance in the treatment of pressure ulcers of the foot and may shorten the recovery process.
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Posts tagged DV72185DX
Unboxing of HP DV7-2185DX25
This is my unboxing of my new HP DV7-2185DX! I got it as an exchange for a returned DV7-1285DX, which I got as an exchange from Best Buy because of my accidental damage plan from a DV7-1025nr, which I also got as an exchange from my accidental damage plan from Best Buy from a DV-9260NR. The first HP I got in 2007, and it fell down the stairs because I was using it on my lap, and my brother scared the crap out of me, making me jump up, dropping the laptop down a whole flight of stairs. The second laptop, which I really liked a lot, got ran over by my mom because I left it on the ground when I was looking up instructions on how to install a gyro system on my bike. Then the 3rd laptop had battery problems and a bad resolution, so I returned it to get this. I did make an unboxing for the 3rd laptop, but since I only owned it for 2 weeks, I decided not to put it up. Also, this video is a month old, because I didn't get around to editing it
Video Rating: 4 / 5
UNBEATABLE 50% OFF DISCOUNT! Buy Laptop Battery on www.LaptopBatteryLife.com

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If you enjoy outrageous campy farces, like The Complete Works of Shakespeare Abridged, you're bound to enjoy the Flat Rock Playhouse Downtown production of the hilarious satire of theatrical and literary genres, The Mystery of Irma Vep by Charles Ludlam, playing through September 14. The quick-change, cross-dressing antics of veteran comic actors, Scott Treadway and Preston Dyar, will keep you in stitches as they make fun of and celebrate genres such as Victorian melodrama, Wuthering Heights, and the Alfred Hitchcock film, Rebecca. Ludlam even has fun with the title, which is a character from the 1915 French movie serial, Les Vampires and the subtitle, which refers to the penny dreadful, a fiction publication popular in 19th century Britain that featured off-color serial stories, costing a penny a piece.
The action takes place on a stereotypical dark and stormy night at the estate of Lord Edgar, an Egyptologist (Dyar), and his recently wedded second-wife, Lady Enid (Treadway). As Enid adjusts to her new life in the country, she is concerned that Edgar has yet to recover from the mysterious death of his first wife, Irma Vep, whose portrait still hangs over the fireplace.
Much like the Greater Tuna Series, the actors in The Mystery of Irma Vep take on numerous characters and costume changes as the two actors play eight characters of both sexes. The comedy includes references to (or appearances by) vampires, ghosts, mummies and werewolves and is largely acceptable for younger audiences.
The Mystery of Irma Vep was first produced by Ludlam's Ridiculous Theatrical Company. Opening off-off-Broadway in New York City's Greenwich Village in 1984, the farce, which ran for over two years, originally starred Ludlam and his partner Everett Quinton.
Any further description might give some of the plays puns and sight gags away. Suffice it to say that Treadway steals the show as he infuses his characters with expertly timed pratfalls and eye rolls as he trips effortlessly through the plot. Dyar also draws consistent laughter, acting mostly as a straight man to Treadway's antics. The play's nonstop action is aptly directed by Flat Rock Playhouse guest director, Kenneth Kay, and expertly designed by scenic designer, Dennis Maulden. The show also owes much of its success to the campy costumes designed by Ashli Arnold.
Performances of The Mystery of Irma Vep at the Flat Rock Playhouse Downtown through September 14 will be held Wednesday through Saturday at 8:00 pm, with matinees Thursday, Saturday, and Sunday at 2:00 pm. All tickets are $40 and can be purchased by calling the Playhouse box office at 828-693-0731, toll-free at 866-732-8008 or online at www.flatrockplayhouse.org.
Discounts are available for seniors, AAA members, military personnel, students and groups. The Flat Rock Playhouse Downtown is located at 125 S. Main Street, Hendersonville, NC 28739.


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Ex-Berry Mayor Roy Dobbs to sign copies of his new book
Published: Saturday, March 8, 2014 at 11:00 p.m.
Last Modified: Saturday, March 8, 2014 at 11:10 p.m.
The former five-term mayor of Berry will sign copies of his new book, "Rising Above Mediocrity," from 1 to 3 p.m. March 23 at the Berry Civic Center.
Roy Dobbs, a native of Berry, was a BellSouth retiree when he ran for mayor in 1992.
The Fayette County town was about $100,000 in debt when he took office. When he left office in 2012, Berry had a reserve of more than $1.5 million.
During his tenure, he oversaw the construction of a civic center, a new fire department building, a new water treatment plant and other improvements.
"My book explains that both the good and bad experiences you encounter in life help prepare you for what lies ahead, and often you don't always know what lies ahead," Dobbs said in a news release.
"My life experiences, and especially my 20 years as mayor, taught me that anyone, or any town for that matter, can rise above mediocrity, and I have tried to share my own philosophy for doing that in my book," he said.
Copies of "Rising above Mediocrity" are available on Amazon.com or through Dobbs for $10 each.
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.


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I am reading through Etingof et al's notes on representation theory, and they assert in Exercise 5.4(c) on page 80 that a finite-type quiver has no self-loops. I think the way to show this is to consider the simplest case: a quiver with one vertex and one edge - the self-loop. Representations of this quiver correspond to a choice of vector space $V$ and any linear endomorphism $T: V \to V$. I should be able to simply write down an infinite family of nonisomorphic indecomposable representations, but I'm not very good at seeing which representations are indecomposable/nonisomorphic. Can someone give me a hint?
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Here is one infinite family of pairwise non-isomorphic indecomposables. Take $V$ to be $F^n$ (your base field $F$) a nilpotent matrix with a single Jordan block for $T$: any submodule must contain the (unique up to scalars) vector in the kernel, so these are indecomposable.
Here is another, if the base field is infinite: take for $T$ the scalar matrix $T=a$ for $a \in F$, acting on a one-dimensional $V=F$. These are simple and non-isomorphic. The real issue here is the infinite dimensionality of the path algebra...


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A review of the Castello di Amorosa experience
Here on The Cork Board we've covered Daryl Sattui's brand-new castle winery, Castello di Amorosa, quite extensively–writing about it a couple times before it opened and providing a glimpse of what it looked like the day it officially opened to the public. Today, we're bringing you multiple photos of the "castle of love" (the English translation) and our review of the visiting experience.
Now, before we go any further, let us state for the record we are quite cognizant of the fact that many of the things we experienced on day-one will be ironed out (and probably already have) as the staff get settled into their roles and the winery is done being built. So, lets get to it…
The winery: We drove up the long, slightly winding-driveway past the budding vines and at the crest saw the massive castle, outlined by the brown dirt upon which it sits. Workers were busily planting olive trees around the outside of the castle and working on various other things. There were a few folks milling about in the parking lot (an artist painting a picture of the structure), but as the winery officially opened to the public on a Monday, things were relatively quiet.
As we got out of the car, gathered our things and started to walk toward the castle, we noticed a man sitting in the middle of the stairs leading up to the main entrance. Dressed in blue jeans and a light shirt, the grey-haired man was talking on his cell phone and looking out toward us. We immediately realized we were looking at Dary Sattui, the guy who spent the past 13+ years and millions of dollars building Castello di Amorosa. As we approached, he got up and walked behind the massive wooden doors–disappearing from our view and still talking on the phone. At the top of the stairs we paused to take in the eastward-view across the Napa Valley and to snap a few photos.
Before we knew it, we were having a private, one-on-one conversation with Mr. Sattui, shaking hands and talking about the winery, the opening and how we heard about it. Sattui was kind enough to pose for a photo for us (which we've posted here) right in front of the main entrance.
He was quite welcoming and clearly happy to have finally seen his dream come to fruition. After our chat, we went inside, bought our tickets for the tour and tasting ($25 per person) and set about doing some of our own exploration of the castle.
The tour: While supposed to be no more than 12 people (per the ticket), our tour (the winery's second-ever) included a little more than 20 people evenly divided between locals and tourists. Before we got started, Sattui posed with the group for a picture (taken by our tour guide Lynn) to commemorate the grand opening.
The tour took us all over the 121,000 square foot castle, up and down the seven levels–where we learned about Sattui's obsession with art, architecture and attention to detail (such as the 1,000 pound authentic wooden doors). With such a large group, we found it difficult to hear everything being discussed and had to wait several times for everyone to finish taking pictures and catch-up with the rest of the tour. At a little over an hour in length, the tour focused a bit too much on the structure itself and not enough on the wine and winemaking process for our taste.
We visited the 'Great Hall' with frescos on every wall and learned the castle has an on-site church and steeple, which may someday be available for weddings. The castle was built in an area of the valley originally settled by the Wappo. Apparently the first ten years of construction were focused on building the four underground levels of cellars and caves. This is where the wines are stored and aged and is home to the torture chamber, which includes a 15th century iron maiden, among other frightening items.
The staff: Everyone we encountered was friendly and welcoming. The staff were undoubtedly working out the kinks–figuring out where to position themselves, learning the best routes to navigate the 107-room castle, etc. The tour in particular will certainly only get more polished and informative as time goes on.
The tasting room: The tasting room, like the rest of the castle, was large and roomy and still very much a work in progress (for example, we had to pour our excess wine into plastic cups after each tasting). The room, which gives off a feel of elegance and royalty, is outlined with wine bottles stacked neatly about waist-high. The tasting area features a thick white and black marble countertop underneath large brick arches and offers plenty of room for patrons.
The wine: We had a six-flight tasting of wines that are only sold at the winery or through the wine club. We started with the 2004 Chardonnay Bien Nacido Vineyard ($36). This chardonnay, from vineyards in Santa Barbara, was full-bodied and gave off a strong boquet of toasty oak. On the palate were tropical fruits and a strong buttery taste. Up next was the 2005 Pinot Bianco ($24) from the Carneros region of the Napa Valley. Pinot Bianco is a dry white wine originally from France's Burgundy region–we found it very fruity (banana, apricot) and sweet. The third wine was the 2005 Gewurztraminer "Dry" ($21). Grown in Mendocino County, this wine had citrus and rose on the nose and was surprisingly spicy on the palate.
We then moved onto the reds, starting with Castello di Amorosa's house red–the 2004 'Il Brigante' ($20). The 2003 La Castellana Super Tuscan ($48) is a blend of Cabernet Sauvignon, Sangiovese and Merlot grapes. We enjoyed the hints of black pepper and black cherry on the nose and the long, lingering finish. The final tasting was a 2003 Il Barone Reserve Cabernet Sauvignon ($68) from Napa Valley. Grown on Diamond Mountain (the vineyard on the left as you come up the driveway to the castle), the Il Barone was aged in French oak for two years and is big and bold. With an interesting combination of black olives, herbs and plenty of tannins, this wine was our favorite of the six.
The Cork Board rating: 3 corks (out of 5 possible). If you're looking for a great way to spend a few hours being entertained and educated while sipping a little wine, then a visit to the "castle of love" will be right up your alley. Castello di Amorosa will undoubtedly be a big hit with tourists and anyone looking for a unique place to host an event.
If you're one who visits the Napa Valley with a thirst for wine and wine-alone, then you should have a specific strategy for Castello di Amorosa. With the massive, gorgeous castle staring us in the face at all times, we found it difficult to concentrate on much else (like the wine). While on the tour we heard others mutter the word "Disneyland" at least three times, indicating to us they no longer felt as though they were in the Napa Valley. Personally, we enjoy a quieter place where we can talk to the winemaker, walk the vineyards and focus on the wine. For the wine enthusiast, we might suggest skipping the tour altogether and heading straight for the tasting room to give the wines a try.
The bottom line is the castle is a must-see if for nothing other than the sheer amazement of it.
[techtags: Napa, Napa Valley, Castello di Amorosa, Calistoga, castle winery, wine, winery, Sattui, 94515]


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This is bab #2 for us and I think we may be done. Although we are still young and we aren't making any perminent decisions, I think this may be it. Our reasoning is I hate being pregnant but wanted DD to have a sibling. I think an exception may be if we decide to be foster parents and decide to adopt a child. I have always wanted to do foster care so this is something for some reason have always considered an option for us. Anyone else done? How mae will this make and how do you know your done??
Who is done after his baby?
I always thought we would be done after 2, but now that I am pregnant for the 2nd time I am having a hard time imagining that this will be the last time that I do this... So I really dont know. The first 2 will be 5 years apart, and we are still young (I am 26) so I could still wait another 5 years after this baby and have another if I want to.
Me: 26, DH: 28
DS: May 22, 2008 (. Y .)
DD: May 22, 2013 (. Y .)
this is our second and we plan to be DONE after this one.....the fact I am so sick confirms that is the right choice!
Personally I would like to say how thrilled I am to see a few same sex partners here! I know a little off topic but I have some friends who had two children together about 20-25 years ago and it was very hard for them back then to not only get pregnant (I believe they had a hard time finding a doctor to do IVF) and the judgement they had to deal with was awful. I am very proud that (for the most part) our society has become accepting of same sex coupls raising children.
April & Jesse 6/28/09
Olivia Rose 5/3/10
Our Little Bean Due 5/27/13
DD~ August 2011 DS~ April 2013
Due may 21st! ... Mommy to Chloe ..Soon to be Married <3
This will be #3. I really want to be done after this because I have hypermesis and don't think I can go through this again. Now to tell DH......
"I'm guessing you weren't burdened with an overabundance of schooling." -Capt. Malcolm Reynolds
Mama To Ashlyn Marie 7/30/11 and Aaron Robert 5/8/13
BF'in, AP'in, co-sleepin', gluten free eatin', grad schoolin' mama!
I ROCK my gold boobies!
My little monkey born 4-30-09 and baby turtle born 5-09-13
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Athletics Home
Sports in the News
Eleven Victories In A Row For Women's Basketball
In the past five days, Los Angeles Trade Tech College learned how tough it really is to play in the South Coast Conference North Division for women's basketball. After stringing together a 17-game winning streak to open the season, The Lady Techsters ran into the twin buzzsaw called Pasadena City College and Mt. San Antonio, two teams that have dominated the state the past several seasons.
After Mt. SAC ended Tech's run, 61-50, on January 15, the defending state champion Lancers sent Trade Tech to 0-2 in conference with a 65-60 road victory Wednesday night. PCC extended its current win streak to 11 games and improved to 18-2 overall and 2-0 in SCC North play.
Pasadena sophomore guard Kim Smith is making a serious case for possible regional player of the year honors after another stalwart effort. Smith tied her 2009-10 season-high with 27 points, making 10-for-15 from the field, 5-for-6 from the free throw line, and hitting two 3-pointers. Her two free throws with 19 seconds left put the game away.
The Lancers led 36-24 before a Trade Tech run sliced the lead to 40-35 at halftime. Trade Tech briefly took a lead early in the second half, but PCC controlled most of the final 20 minutes to secure the triumph.
For PCC, frosh center Dominique Scott tallied 13 points, 10 rebounds, 2 blocks and 3 steals. Sophomore guard Melissa Fudge came off the bench for 6 points and 4 steals.
Trade Tech was led by a familiar face in Niauni Brown, who played for PCC three seasons ago as an All-SCC Second Team forward. Brown has become one of LATT's top players as she netted 20 points and 6 rebounds against her former college.
PCC hosts East Los Angeles College Friday, January 22 in a 5:30 p.m. SCC contest at Hutto-Patterson Gymnasium.
Lancer Notes: PCC had held its previous three opponents to under 50 points ... In last season's state title run, the Lancers lost their ninth game against Fullerton College to fall to 7-2, then put together a 16-game winning streak. This season, PCC could be duplicating the pattern, as its last defeat was against Fullerton in the ninth game this season on December 4. The team's record was also 7-2 after that loss, and now the current double-digit win streak. Could this be Deja vu for the Lancers? ... Going back to the start of a 6-year streak of reaching the CCCAA Championship Tournament in the 2003-2004 season, PCC Head Coach Joe Peron's record is an astonishing 194-25, an .886 winning percentage. In now his 14th season, Peron has a career mark of 342-88, a .795 clip.
[Photo--Kim Smith delivers a fake shot then pass during PCC's 65-60 victory at Los Angeles Trade Tech College Wednesday evening. Smith has 49 points in two conference wins, image by Richard Quinton.]
Release Date: 01/20/10
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