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Atheists Want Your Young Daughters to Lose Virginity (poll)
Why would an adult be against anything that helps keep our children chaste? You would think anyone who is not a sicko would applaud such things, but no, we should have guessed atheists are against such morality.
[poll id="2″]
Even our old "friend" PJ Meyers decided to poke fun at a serious message to young women, which was telling them that their bodies are precious and that they should keep their secret gardens pristine until they are married to their husband. PJ and his little cohort of atheist goons labeled the message "kooks", implying whoever says this stuff is crazy. Just look:
People send me stuff via email, and I browse through it all in the early morning, before I go offline and get to work, and that means I often wake up to some of the most disgusting, revolting, horrible messages: death threats, angry letters, and all kinds of interesting insults. But sometimes the worst comes from people who are on my side, like this message that really ruined my breakfast. It's from a Catholic anti-choice site, full of prim certainties about gods and babies and your reproductive organs, and it has this…this…letter to a young girl, written by Alice von Hildebrand.
Be prepared to hurtle back and forth from hilarity to revulsion.
Let us take off our "secular" eyeglasses, and then we shall be able to see that women, far from being "discriminated" against, are in many ways privileged. And this is the "secret" I wish to share with you. The body of every little girl born into this world is mysteriously sealed by what is properly called the "veil of virginity". That is to say, a "secret" is entrusted to her body, and a secret is always "veiled". According to Christian teaching, this veil closes the entrance to a mysterious garden which belongs to God in a special way, and for this reason cannot be entered into except with His express permission, the permission that God grants spouses in the Sacrament of Matrimony. Any little girl aware of this "mystery" will feel that her body is to be modestly clothed, so that its secret will be hidden from lewd looks.
Little girls, of course, grow up. How beautiful when a bride can say to her husband on their wedding night, "I have kept this garden virginal for you, and now, with God's permission I am giving you its key, knowing that you will enter into it with reverence".
Moreover, when a wife conceives a few hours after her husband has embraced her, God creates the child's soul in her body, (as you certainly know, neither husband nor wife can produce the human soul; God alone can create it.) In other words, there is a personal "contact" between God and the woman which, once again, gives to the female body a note of sacredness. Don't forget that He whom the whole universe cannot contain, was "hidden" in the womb of the Holy Virgin for nine months. Once you realize this, you will be awe-filled for the double mystery that God has confided to you: to conceive a human being made to God's image and likeness, and to give birth to it in pain and anguish. Do not forget that it was also in pain and anguish that Christ re-opened for us the gates of paradise – which had been shut by sin. To women has been granted the awesome privilege of nobly suffering so that a new human being, made to God's image and likeness, might come into the world. Meditate upon this for a moment, and you will feel a deep reverence for your body. It belongs to God, and is not a "play thing" that you can dispose of as you please.
Wow. In a few short paragraphs, she's managed to promote the cult of virginity, insist on magical ensoulment at the instant of conception, belittle the struggle for equality of women, glorify pain, and imply that anyone who doesn't follow Catholic dogma is throwing away their body…and she does it with a kind of Victorian smugness that alone is rather off-putting.
I think I'll go take a shower now.
Now we see someone sent him that letter and as a scholar, I would hope that this Meyers would have used his authority to tell his students that this was a great letter and they should all be teaching these things to little girls. It's just the responsible thing to do.
Instead, we can see it is labeled "kooks" and the comments that are against the letter are not even properly contested or removed.
It is important to teach our children to remain chaste so they don't catch AIDs or herpies or worse. Atheists are a scourge upon humanity and it is nigh time we prayed them into the fringe cult that they are.
These atheists create all these scenarios which lead children away from the purity of childhood into the dark world of secularism, then try to point fingers at everyone else: Christians, blacks, Mexicans and even the poor.
They try to hide behind their pointed fingers and veil racism, when the truth is that they and their liberal laws and anti-God mentality is to blame. A pure heart is a chaste heart, and there is nothing an atheist hates more than chastity in the heart. So let's see the numbers and the stats in the poll so we can make it scientific how these diseased atheists are responsible for the rise in teen afflictions.
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For any non-empty set $S$ and predicate $p$ defined on $S^2$ prove or disprove $\forall x\in S\exists y\in S p(x,y)\to \exists y\in Sp(y,y)$
I'm trying to prove the above. First of all i need to know whether the statement is true or false.. Here how to change $p(x,y)$ to $p(y,y)$?? pretty confused..

subset: commoncrawl


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Yesterday, March 6, 2014, Sony informed us that Jack Tretton, a founding member of Sony PlayStation North America division and it's long time head is stepping down at the end of March. Tretton has been a constant PlayStation figurehead from the start. He helped PlayStation thrive from an upstart to a powerhouse that overthrew Nintendo.
According to a statement Sony issued, the decision not to renew Tretton's contract was mutual. Sony's current Network Entertainment International executive vice president Shawn Layden will take over as prsident and CEO.
Tretton has a solid foundation in selling physical products, Layden however, has spent the last few years developing a digital presence. Could this change represent a shift toward defining a digital dominance?
Tretton's tenur placed him among the longest serving executives in the North American video game industry. So naturally he couldn't leave without a few words of encouragement. "Working at SCEA for the past 19 years has been the most rewarding experience of my career", said Tretton.
"Although I will deeply miss the talented team at SCEA and the passion demonstrated everyday by our fans, I'm very excited about starting the next chapter of my career. I want to thank the employees, partners and customers for their tireless commitment to the PlayStation brand and, of course to our fans, who have pushedusto new heights of innovation and entertainment over the past two decades. I leave PlayStation in a position of considerable strength and the future will only get brighter forPlayStation Nation."
He also took the PlayStation Blog to personally thank PlayStation Nation for their continued support. Does anyone else need a tissue?


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Encina Veterinary Hospital
(925) 937-5000 Ext. 1
2803 Ygnacio Valley Road, Walnut Creek CA 94598
24 Hour Emergency Care
Encina Veterinary Hospital offers 24-hour emergency care if your pet is sick or injured and needs urgent care after hours. A doctor is available 24 hours a day, 7 days a week. If you suspect that your pet is experiencing a medical emergency, call us at 925-937-5000, extension #1.
Our hospital is staffed overnight to provide around-the-clock monitoring and nursing care for all hospitalized patients; your pet is never alone. Having advanced diagnostic equipment and an intensive care unit (ICU) provides lifesaving measures especially when your pet has an emergency and time is of the essence.
Please use care when handling your pet if he or she has been injured. We encourage you to call us at 925-937-5000 before coming in so that we can prepare for your arrival. When you arrive at EVH, your pet will immediately be triaged so that we may determine his or her stability. If your pet needs to be hospitalized, the admitting veterinarian will discuss with you the proposed treatment plan.
There are thousands of pets available from over 100 California rescue organizations, just waiting for your love. Find your match today! Search Adoptions


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"Coconut what?" I asked, a bit confused… "The coconut wireless mate. It's what the locals call it, you know, the rumor mill, the local gossip makin' it's way from busy body to busy body." More on this in a minute…[tell-a-friend id="1″ title="Share this article with a friend!"]Chris and I both rolled into Fiji a couple of days ago. After barely making our flight out of Auckland and then missing our inter-island connection (apparently Chris thinks 30 minutes is easily enough time for a connection off an international flight!) we spent a brief evening in Nadi before heading over to Savusavu to meet up with a few colleagues.
We kept this trip quiet, as we only had a few days, and we didn't want to offend those we just wouldn't have the time to see (Sorry guys!). Too late, as the aforementioned coconut wireless was in high gear. Apparently most of the town knew we were coming before we even touched down! Such is life on a small island.
The agenda for this trip was a quick meet with our JV partner for the resilient, safe-haven development we're working on. He was kind enough to host us and truck us around the property for the last 2 days. We also met up with our farm manager, a heck of a nice guy whom some of you met at our last Meet Up in Fiji.
Chris and I have been a bit nervous about the progress, as this is a big project for us, and development is not our expertise. Of course we couldn't have picked a better partner, a guy with over 35 years of development experience in the South Pacific, he's truly an artist with the land. This last 2 days has convinced us that this project will be very special and unique indeed!
Like our JV partner, our farm manager was also an incredible find. One of the nicest guys you'll ever meet, with a wealth of knowledge that we're already tapping into. He'll be overseeing the rejuvenation of our 2,000 organic vanilla plants and dozens of cocoa trees that were left unattended for the last couple of years. His "canvas" will be over 100 acres of rich, black volcanic soil where we intend to graze cattle, goats, pigs, chickens and duck… not to mention planting everything from avocado to zapallito.
It's our intention to host an open house on the property within the next 3 months. The timing is still a bit uncertain, but we'll be discussing it regularly herein.
If this is all news to you, stay tuned or drop us a line and let us know you have an interest. We're not building a mega-project here, but rather looking for a few dozen folks who think it might be nice to be part of something special in one of the most beautiful places on earth, bar none.
A few more pics to whet your whistle… enjoy!
More on Fiji in a couple of days…
– Mark
"Man can now fly in the air like a bird, swim under the ocean like a fish, he can burrow into the ground like a mole. Now if only he could walk the earth like a man, this would be paradise." – Tommy Douglas
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Dec. 17, 2007 -- Psoriasis is not generally thought of as life-threatening, but it just might be for those with the severest forms of the disease.
People with severe psoriasis had a 50% increased risk of death compared with people without the inflammatory skin disease in a newly reported study.
Men with severe psoriasis died an average of 3.5 years earlier than men without the condition, while women with severe psoriasis died 4.4 years earlier than women without psoriasis.
Having mild psoriasis was not associated with an increased risk of death, and the researchers did not have information on causes of death.
But researcher Joel M. Gelfand, MD, says the findings make it clear that patients with severe psoriasis are at greater risk than has been realized.
"To put this in perspective, this finding suggests that more years of life are lost related to severe psoriasis than to severe hypertension," he tells WebMD.
Psoriasis and Death
As many as 7.5 million Americans have psoriasis, according to the National Institutes of Health.
About 80% to 85% of patients have mild to moderate psoriasis, while 15% to 20% have more extensive skin involvement. These patients generally require treatment with systemic medications like the drugs methotrexate and cyclosporine or newer biologics such as Enbrel, Remicade, and Humira.
Using a national medical records database from the U.K., Gelfand and colleagues from the University of Pennsylvania School of Medicine identified 133,568 patients with mild psoriasis, defined as having a diagnosis of psoriasis but no history of treatment for the condition.
An additional 3,951 patients were identified with severe psoriasis.
For each patient, up to five people without psoriasis who visited doctors for other causes were used for comparison.
During the study period, the death rate among patients with severe psoriasis was almost twice as high as in patients without psoriasis (21.3 deaths per 1,000 individuals per year vs. 12 deaths per 1,000 individuals per year).
During the study period, patients with severe psoriasis had a 50% increased risk of death compared with those without psoriasis. Those with milder psoriasis didn't have an increased risk of death compared to those without psoriasis.
The study appears in the December issue of the Archives of Dermatology.


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Shake Shack supports Waterkeeper Alliance
Shake Shack is a modern day "roadside" burger stand serving the most delivious burgers, friends, hot dogs, frozen custard, beer, wine and more! With fresh, simple, high-quality food at a great value, Shake Shack is a fun and lively community-gathering place with widespread appeal. From their ingredients and hiring practices to our environmental responsibility, design and community investment, Shake Shack's mission is to continually Stand for Something Good®.
" 1% of every bottle of our SHACK2O natural spring water sold goes to the Waterkeeper Alliance, supporting the cleanup of water sources around the globe. Our partnership with the Waterkeeper Alliance, about 3 years strong, is a cornerstone of our commitment to Stand For Something Good®. As we open more Shacks in new areas, we're proud to be spreading the good word about this amazing organization and the work that they do to empower member Waterkeeper organizations in protecting communities, ecosystems and water quality. Inspired by our work with the Waterkeeper Alliance, we also recycle bottles, cardboard, and plastics at the Shack; reuse our cooking oil to produce clean energy; and construct every location with recycled and sustainable materials. We're working hard to lessen our footprint, and promise to keep pushing to make important new strides. In all of our efforts to Stand For Something Good, we're grateful to our guests for standing with us."
Find out what Custard is being featured today at your Shack!


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Soleil Moon Frye was a household name when "Punky Brewster" was on television. The actress with the unique name is all grown up and married with children. Frye is very active on Twitter and often is seen out and about with celebrity friend Melissa Joan Hart. According to a Feb. 11 report from E! Online, Soleil Moon Frye welcomed her third child with husband, Jason Goldberg into the world yesterday. The couple was blessed with a little boy and they have two daughters already at home.
While doing television appearances last year, Soleil Moon Frye announced her pregnancy and the gender of the baby. She admitted to being shocked about the gender because after having two little girls, she was almost sure she was having another daughter. Frye is often talking about parenting or giving advice about it. She has plenty of followers on Twitter and she engages her followers on a regular basis.
The name of the newest addition to the family has not yet been released, fans believe it will be on the unique side of the fence. Soleil Moon Frye is quite the name, and both her girls have off-the-wall names like Poet and Jagger. Fans are sending love and well wishes to the new parents and the big sisters.
To be among the first to receive news from the Chicago Celebrity Examiner, please subscribe here or at the top of the page. It's anonymous and completely free. You can contact the Chicago Celebrity Examiner by emailing email@example.com.
Suggested Links
- Is 'Pretty Little Liars' star Ashley Benson engaged?
- Selena Gomez stands up to bullying fan response on Instagram
- Justin Bieber arrested in Miami: Is rehab the next stop?
- 'Pretty Little Liars' actress Troian Bellisario opens up about eating disorder
- Sophia Bush helps support Chicagoan 'Sole of the Year' winner Sue Naiden


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Bird's Tutorials
TUTORIAL: Easy Ribbon WreathWednesday, April 18, 2012C Riches
Our Spring/Summer magazine has been a HUGE success so far and we've already reached over 360,000 unique page views since Friday, and I only have you guys to thank for helping spread the word!! ;)
But now I'll be taking a little bloggy break this month and slowing down on my posts - I need to re-group myself, catch up on family-time, do the laundry, and work on some new party projects!
But today I'm guest posting over at The Ribbon Retreat Blog, where I show you how to make a ribbon wreath that is super easy!!
I used Holiday colors, but with the same technique and the HUGE selection of ribbons offered at The Ribbon Retreat, I'm sure you could come up with a wreath for each season!!
Hope you like it, and feel inspired to make one too!! Check the full tutorial here.


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"Clinical Pharmacogenetics Implementation Consortium guideline for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants." has been saved, and will be accessible from the My NGC page.
Go to My NGC
Alert me when this guideline summary is updated.
This is the current release of the guideline.
To provide information regarding how to use existing cytochrome P450 2D6 (CYP2D6) and/or CYP2C19 genotyping test results to guide dosing of tricyclics for psychological disorders and pain management, focusing particularly on amitriptyline and nortriptyline
Dosing of tricyclic antidepressant therapy (amitriptyline, nortriptyline) based on cytochrome P450 2D6 (CYP2D6) and CYP2C19 genotype
The guideline authors searched the PubMed® database (1966 to September 2012) for the following keywords: (cytochrome P450 2D6 or CYP2D6) OR (cytochrome P450 2C19 or CYP2C19) AND (tricyclic antidepressants OR amitriptyline OR clomipramine OR desipramine OR doxepin OR imipramine OR nortriptyline OR trimipramine) for the association between CYP2D6 and/or CYP2C19 genotypes and metabolism of tricyclic antidepressant drugs or tricyclic antidepressant-related adverse drug events or clinical outcomes.
The cytochrome P450 2D6 (CYP2D6) and CYP2C19 allele frequency tables are based on previously published Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines. Updates to the CYP2D6 allele frequency table were made by searching the PubMed® database (1995 to June 2012) using the following key words: CYP2D6, CYP 2D6, cytochrome P4502D6, ethnic, ethnicity, race, population, and names of countries and populations (e.g., Spain, Spanish, Brazil, Brazilian). In addition, reports were also identified from citations by others or review articles. Studies were considered for inclusion if: (1) the ethnicity of the population was clearly indicated, (2) either CYP2D6 allele frequencies or genotype frequencies were reported, (3) the method by which CYP2D6 was genotyped was indicated, (4) the sample population consisted of at least 50 individuals with a few exceptions (e.g., smaller cohorts that were part of larger studies) and (5) the study represented an original publication (no reviews or meta-analyses).
Not stated
Levels of Evidence
High: Evidence includes consistent results from well-designed, well-conducted studies.
Moderate: Evidence is sufficient to determine effects, but the strength of the evidence is limited by the number, quality, or consistency of the individual studies; generalizability to routine practice; or indirect nature of the evidence.
Weak: Evidence is insufficient to assess the effects on health outcomes because of limited number or power of studies, important flaws in their design or conduct, gaps in the chain of evidence, or lack of information.
The Clinical Pharmacogenetics Implementation Consortium (CPIC) therapeutic recommendations are based on weighting the evidence from a combination of preclinical functional and clinical data, as well as on some existing disease-specific consensus guidelines. Some of the factors that are taken into account in evaluating the evidence supporting therapeutic recommendations include: in vivo pharmacokinetic and pharmacodynamic data, in vitro enzyme activity of tissues expressing wild-type or variant-containing cytochrome P450 2D6 (CYP2D6) or CYP2C19, in vitro CYP2D6 or CYP2C19 enzyme activity from tissues isolated from individuals of known CYP2D6 or CYP2C19 genotypes, and in vivo pre-clinical and clinical pharmacokinetic and pharmacodynamic studies. The gene-based dosing recommendations in this guideline takes into consideration the effects CYP2D6 or CYP2C19 genetic variants may have on both clinical outcomes and tricyclic plasma concentrations. Because the pharmacokinetic properties of tricyclic antidepressants do not differ between healthy volunteers and patients, the guideline authors evaluated pharmacokinetic data acquired from studies performed on healthy subjects and patients to assist in determining if CYP2D6 or CYP2C19 genetic variants affect tricyclic plasma concentrations.
The therapeutic recommendations are simplified to allow rapid interpretation by clinicians. They have been adopted from the rating scale for evidence-based therapeutic recommendations on the use of retroviral agents found at http://aidsinfo.nih.gov/contentfiles/AdultandAdolescentGL.pdf (see the "Rating Scheme for the Strength of the Recommendations" field.
Strength of Therapeutic Recommendations
Strong: The evidence is high quality and the desirable effects clearly outweigh the undesirable effects.
Moderate: There is a close or uncertain balance as to whether the evidence is high quality and the desirable clearly outweigh the undesirable effects.
Optional: The desirable effects are closely balanced with undesirable effects and there is room for differences of opinion as to the need for the recommended course of action.
A formal cost analysis was not performed and published cost analyses were not reviewed.
The strength of therapeutic recommendations (Strong, Moderate, Optional) is defined at the end of the "Major Recommendations" field.
Genetic Test Interpretation
The cytochrome P450 2D6 (CYP2D6) activity score is used to assign phenotype in this guideline as follows: patients with an activity score of 0 are classified as poor metabolizers, those with a score of 0.5 are intermediate metabolizers, those with a score from 1.0 to 2.0 are extensive metabolizers, and those with a score >2.0 are classified as ultrarapid metabolizers (see Table 1 below and Supplementary Data in the "Availability of Companion Documents" field). Extensive metabolizers are considered to have normal CYP2D6 enzyme activity.
Table 1. Assignment of Likely Phenotypes Based on Diplotypes
Ultrarapid metabolizer (~1–2% of patients)b
An individual carrying duplications of functional alleles
(*1/*1)xN, (*1/*2)xN,
Extensive metabolizer (~77–92% of patients)
An individual carrying two functional alleles or two reduced function alleles or one functional and nonfunctional allele or one functional and reduced function allele
*1/*1, *1/*2, *2/*2, *1/*9,
*1/*41, *41/*41, *1/*5,
Intermediate metabolizer (~2–11% of patients)
An individual carrying one reduced function and one nonfunctional allele
*4/*41, *5/*9, *4/*10
Poor metabolizers (~5–10% of patients)
An individual carrying only nonfunctional alleles
*4/*4, *3/*4, *5/*5, *5/*6
Ultrarapid metabolizer (~5–30% of patients)e
An individual carrying two gain-of-function alleles or one functional allele and one gain-of-function allele
*17/*17, *1/*17
Extensive metabolizer (~35–50% of patients)
An individual carrying two functional alleles
Intermediate metabolizer (~18–45% of patients)
An individual carrying one functional allele and one loss-of-function allele
*1/*2, *1/*3
Poor metabolizers (~2–15% of patients)
An individual carrying two loss-of-function alleles
*2/*2, *2/*3, *3/*3
a See Supplementary Data in the "Availability of Companion Documents" field for additional information about CYP2D6 activity score and its limitations.
b CYP2D6 metabolizer status frequencies are based on data from Caucasians and may differ from other ethnicities.
c xN represents the number of CYP2D6 gene copies.
d Patients with an activity score of 1.0 may be classified as intermediate metabolizers by some reference laboratories.
e CYP2C19 metabolizer status frequencies are based on average multiethnic frequency.
Therapeutic Recommendations
CYP2D6 Dosing Recommendations
For neuropathic pain treatment, in which lower initial doses of tricyclics are used, gene-based dosing recommendations are found in the "Other Considerations" section, below. Table 2, below, summarizes the gene-based dosing recommendations for amitriptyline and nortriptyline based on CYP2D6 phenotype for situations requiring a higher initial dose, such as depression treatment. The recommended starting dose of amitriptyline or nortriptyline does not need adjustment based on genotype for CYP2D6 extensive metabolizers. A 25% reduction of the recommended dose may be considered for CYP2D6 intermediate metabolizers. Because patients with a CYP2D6 activity score of 1.0 are inconsistently categorized as intermediate or extensive metabolizers in the literature, these are difficult to evaluate, resulting in a moderate recommendation classification.
CYP2D6 ultrarapid metabolizers have a higher probability of failing amitriptyline or nortriptyline pharmacotherapy due to subtherapeutic plasma concentrations, and therefore alternative agents are preferred. There are documented cases of CYP2D6 ultrarapid metabolizers receiving large doses of nortriptyline to achieve therapeutic concentrations. However, very high plasma concentrations of the nortriptyline hydroxy metabolite were present, which may increase the risk for cardiotoxicity. If a tricyclic is warranted, there are insufficient data in the literature to calculate a starting dose for a patient with CYP2D6 ultrarapid metabolizer status, and therapeutic drug monitoring is strongly recommended. Adverse effects are more likely in CYP2D6 poor metabolizers due to elevated tricyclic plasma concentrations, therefore, alternative agents are preferred. If a tricyclic is warranted, consider a 50% reduction of the usual dose; therapeutic drug monitoring is strongly recommended.
Table 2. Dosing Recommendations for Amitriptyline and Nortriptyline Based on CYP2D6 Phenotype
If CYP2C19 genotyping results are also available, see Table 3, below, for CYP2C19-based dosing recommendations along with Supplementary Data online (see the "Availability of Companion Documents" field). Dosing recommendations apply only to higher initial doses of amitriptyline or nortriptyline for treatment of conditions such as depression. See "Other Considerations", below, for dosing recommendations for conditions in which lower initial doses are used, such as neuropathic pain. For the dosing guidelines for clomipramine, desipramine, doxepin, imipramine, and trimipramine, see Supplementary Data online.
aPatients may receive an initial low dose of tricyclics, which is then increased over several days to the recommended steady-state dose. The starting dose in this guideline refers to the recommended steady-state dose.
CYP2C19 Dosing Recommendations
Dosing recommendations for neuropathic pain treatment with amitriptyline are discussed in the "Other Considerations" section, below. Table 3, below, summarizes the gene-based dosing recommendations for CYP2C19 and amitriptyline when higher initial starting doses are warranted. The usual starting dose of amitriptyline may be used in CYP2C19 extensive and intermediate metabolizers. Although CYP2C19 intermediate metabolizers would be expected to have a modest increase in the ratio of amitriptyline to nortriptyline plasma concentrations, the evidence does not indicate that CYP2C19 intermediate metabolizers should receive an alternative dose.
Patients taking amitriptyline who are CYP2C19 ultrarapid metabolizers may be at risk of having altered plasma concentrations or adverse events. Although the CYP2C19*17 allele did not alter the sum of amitriptyline plus nortriptyline plasma concentrations, it was associated with higher nortriptyline plasma concentrations, possibly increasing the risk of adverse events. For patients taking amitriptyline, extrapolated pharmacokinetic data suggest that CYP2C19 ultrarapid metabolizers may need a dose increase. Due to the need for further studies investigating the clinical importance of the CYP2C19*17 allele and the possibility of altered tricyclic concentrations, the guideline authors recommend consideration of an alternative tricyclic or other drug not affected by CYP2C19. Because the clinical importance of CYP2C19*17 is currently poorly understood, this recommendation is classified as optional. If amitriptyline is administered to a CYP2C19 ultrarapid metabolizer, therapeutic drug monitoring is recommended.
CYP2C19 poor metabolizers are expected to have a greater ratio of amitriptyline to nortriptyline plasma concentrations. The elevated amitriptyline plasma concentrations may increase the chance of a patient experiencing side effects. Consider a 50% reduction of the usual amitriptyline starting dose along with therapeutic drug monitoring.
Table 3. Dosing Recommendations of Amitriptyline Based on CYP2C19 Phenotype
If CYP2D6 genotyping results are also available, see Table 2, above, for CYP2D6-based dosing recommendations along with Supplementary Data online (see the "Availability of Companion Documents" field). Dosing recommendations apply only to higher initial doses of amitriptyline for treatment of conditions such as depression. See "Other Considerations", below, for dosing recommendations for conditions at which lower initial doses are used, such as neuropathic pain. For dosing guidelines for clomipramine, doxepin, imipramine, and trimipramine, see Supplementary Data online.
CYP2D6 and CYP2C19 Combined Dosing Recommendations
Although specific combinations of CYP2D6 and CYP2C19 alleles are likely to result in additive effects on the pharmacokinetic properties of tricyclics, little information is available on how to adjust initial doses based on combined genotype information. Patients carrying at least one CYP2D6 nonfunctional allele and two CYP2C19 functional alleles had an increased risk of experiencing side effects when administered amitriptyline, whereas patients with at least one CYP2C19 loss-of-function allele and two CYP2D6 functional alleles had a low risk of experiencing side effects. Because there is only sparse clinical evidence for an additive effect of CYP2D6 and CYP2C19 on tricyclic dosing, the recommendations are classified as optional (see online Supplementary Data in the "Availability of Companion Documents" field).
Other Considerations
Gene-based Dosing Recommendations for Neuropathic Pain Treatment
Amitriptyline is often used at lower dosages (e.g., 0.1 mg/kg/day in pediatric patients) for treatment of neuropathic pain than when used for depressive disorders. Because of the lower dosage, it is less likely that CYP2D6 or CYP2C19 poor or intermediate metabolizers will experience adverse effects due to supratherapeutic plasma concentrations of amitriptyline. Therefore, the guideline authors recommend no dose modifications for poor or intermediate metabolizers when prescribed amitriptyline at a lower dose for treatment of neuropathic pain, but these patients should be monitored closely for side effects. If larger doses of amitriptyline are warranted, the guideline authors recommend following the gene-based dosing guidelines presented in Tables 2 and 3, above.
Providing dose recommendations for CYP2C19 ultrarapid metabolizers when amitriptyline is prescribed at lower doses for neuropathic pain treatment is difficult. On the basis of predicted and observed pharmacokinetic data, CYP2D6 ultrarapid metabolizers are at risk of failing amitriptyline therapy for neuropathic pain, and thus alternative agents such as gabapentin should be considered. Although little information is available on how to adjust initial amitriptyline doses based on combined CYP2D6 and CYP2C19 genetic results when treating neuropathic pain, caution should be used when patients have a combination of poor or ultrarapid phenotypes (e.g., a CYP2D6 poor metabolizer also having CYP2C19 ultrarapid or poor metabolism).
Consideration of Drug Interactions and Patient Characteristics
Patients treated for psychiatric disorders often require multiple medications, which can influence tricyclic plasma concentrations, side effects, and therapeutic failure. For example, patients taking amitriptyline in combination with a potent CYP2D6 inhibitor, such as fluoxetine, may have dramatic increases in plasma concentrations. It has been suggested that patients taking strong CYP2D6 inhibitors should be treated similarly to CYP2D6 poor metabolizers. In addition, patients with increased age, liver disease, and reduced renal function may require reduced doses of tricyclics. Drug–drug interactions along with patient characteristics should be considered in addition to the gene-based dosing recommendations presented herein.
Minor Metabolic Pathways of Tricyclics
Other cytochrome P450 enzymes, including CYP3A4 and CYP1A2, metabolize tricyclics to a lesser extent. There is currently no strong evidence supporting gene-based dosing recommendations for other cytochrome P450 enzymes that metabolize tricyclics.
None provided
The evidence summarized in Supplemental Tables S12-18 (see the "Availability of Companion Documents" field) is graded using a scale based on previously published criteria and applied to other Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines (see the "Major Recommendations" field). Every effort was made to present evidence from high-quality original research studies. In addition, the guideline authors took into consideration all available peer-reviewed published literature including other gene-based dosing recommendations.
For patients who have existing cytochrome P450 2D6 (CYP2D6) and/or CYP2C19 genotyping test results, the potential benefit is identifying those patients who are at an elevated risk of experiencing side effects or therapeutic failure. For those patients, dose adjustments can be made or an alternative agent selected.
Caveats: Appropriate Use and/or Potential Misuse of Genetic Tests
The application of genotype-based dosing is most appropriate when initiating therapy with a tricyclic. Obtaining a pharmacogenetic test after months of drug therapy may be less helpful in some instances, given that the drug dose may have already been adjusted based on plasma concentrations, response, or side effects. Similar to all diagnostic tests, genetic tests are one of several pieces of clinical information that should be considered before initiating drug therapy.
Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines reflect expert consensus based on clinical evidence and peer-reviewed literature available at the time they are written; they are intended only to assist clinicians in decision making and to identify questions for further research. New evidence may have emerged since the time a guideline was submitted for publication. Guidelines are limited in scope and are not applicable to interventions or diseases not specifically identified. Guidelines do not account for all individual variations among patients and cannot be considered inclusive of all proper methods of care or exclusive of other treatments. It remains the responsibility of the health-care provider to determine the best course of treatment for a patient. Adherence to any guideline is voluntary, with the ultimate determination regarding its application to be made solely by the clinician and the patient. CPIC assumes no responsibility for any injury to persons or damage to persons or property arising out of or related to any use of CPIC's guidelines, or for any errors or omissions.
An implementation strategy was not provided.
Not applicable: The guideline was not adapted from another source.
National Institutes of Health (NIH)
Authors: JK Hicks, Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee, USA; JJ Swen, Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands; CF Thorn, Department of Genetics, Stanford University, Stanford, California, USA; K Sangkuhl, Department of Genetics, Stanford University, Stanford, California, USA; ED Kharasch, Division of Clinical and Translational Research, Department of Anesthesiology, Washington University in St. Louis, St. Louis, Missouri, USA; VL Ellingrod, Department of Clinical, Social and Administrative Sciences, College of Pharmacy, and Department of Psychiatry, School of Medicine, University of Michigan, Ann Arbor, Michigan, USA; TC Skaar, Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA; DJ Müller, Neurogenetics Section, Centre for Addiction and Mental Health, and Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada; A Gaedigk, Division of Pediatric Pharmacology and Medical Toxicology, Children's Mercy Hospital & Clinics, Kansas City, Missouri, USA; JC Stingl, Division of Research, Federal Institute for Drugs and Medical Devices, University of Bonn Medical Faculty, Bonn, Germany
J.K.H. is supported by NIH/National Institute of General Medical Sciences (NIGMS) Pharmacogenomics Research Network (U01 GM92666 and U01 HL105198) and by ALSAC. C.F.T. and K.S. are supported by NIH/NIGMS (R24 GM61374). E.D.K. is supported by R01 GM63674 and R01 DA14211. T.C.S. is supported by R01 GM088076 and the Agency for Healthcare Research and Quality (R01 HS19818-01). V.L.E. is supported by the NIMH (R01 MH082784). D.J.M. is supported by a New Investigator Salary Award from the Canadian Institutes of Health Research, a New Investigator Fellowship Award from the Ontario Mental Health Foundation, and an Early Researcher Award by the Ministry of Research and Innovation of Ontario. The content is solely the responsibility of the authors and does not necessarily represent the official views of the Agency for Healthcare Research and Quality.
The authors declared no conflict of interest.
Electronic copies: Available from the Pharmacogenomics Knowledgebase Web site .
The following are available:
None available
This NGC summary was completed by ECRI Institute on May 15, 2013. The information was verified by the guideline developer on June 25, 2013.
This NGC summary is based on the original guideline, which is subject to the guideline developer's copyright restrictions.
The National Guideline Clearinghouse™ (NGC) does not develop, produce, approve, or endorse the guidelines represented on this site.
All guidelines summarized by NGC and hosted on our site are produced under the auspices of medical specialty societies, relevant professional associations, public or private organizations, other government agencies, health care organizations or plans, and similar entities.
Guidelines represented on the NGC Web site are submitted by guideline developers, and are screened solely to determine that they meet the NGC Inclusion Criteria which may be found at http://www.guideline.gov/about/inclusion-criteria.aspx.
NGC, AHRQ, and its contractor ECRI Institute make no warranties concerning the content or clinical efficacy or effectiveness of the clinical practice guidelines and related materials represented on this site. Moreover, the views and opinions of developers or authors of guidelines represented on this site do not necessarily state or reflect those of NGC, AHRQ, or its contractor ECRI Institute, and inclusion or hosting of guidelines in NGC may not be used for advertising or commercial endorsement purposes.
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Wednesday, July 27, 2011
Sweet Potato Fries: They're Good, Y'all!
7 comments:
I absolutely adore sweet potato fries!! YUM YUM YUM!! I'll try this recipe - so far my homemade ones arn't all that great (probably b/c I'm not deep frying them). If you ever wanna get frozen ones (hey desperate times call for desperate measures) I have found that the Kroger brand are the BEST! And I think I've just about tried all of them at this point.ReplyDelete
Love that sweet lady, Paula...her magazines are my most-dog-eared ones. Thanks for sharing. :)ReplyDelete
you mean they don't contain a couple sticks of butter? i was pretty sure everything she made did!ReplyDelete
those look great. i'll have to try them!
yeah- Me and that Paula Deen- we are tied at the waist. Butter? Chocolate? Cream? Yep-use them all! There are a few restuarants hee that serve sweet potoato fries on the side. Love them- xo DianaReplyDelete
Hurray for the sweet potato fries! I am a big fan of them myself. Thanks for the link you provided to Paula Deen's recipe.ReplyDelete
I've never been a sweet potato fan (this may be sacrilegious in the south!) but think I'd be much more inclined to splurge on that chocolate cake. It's hard not to love PD though. She's a sweetheart!ReplyDelete
Ahhh look you have Savannah's sweetheart here today.. I wonder how in the world does she cooks all that yummy stuff and still fit into her clothes..I read one of her recipes and gain weight. I'm a big fan of sweet tator's I also like to cut them round and very thin then fry really crisp.ReplyDelete
Have a wonderful weekend and
hugs from Savannah, Cherry
I love hearing from each of you and will do my best to respond! Thanks so much for stopping by. So glad you're here!


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Working it
Thursday, May 16, 2013
Missed a day of logging into Spark, and ruined my 40+ day streak of that. And I've slacked in the water department, and I can definitely see it in skin condition. Yuck! I haven't caved and drank soda though! It's been 51 days without it.
Seriously behind on the wedding stuff however...finished the wedding website last night, and tracked down all but 2 of my invite addresses. Still gotta print the invites and get them ready to go in the mail. Have to make my final dress/veil/flower girl dress payment and set up my fittings too. Yikes. And order bridesmaid gifts, favors and figure out music. SO MUCH TO DO. Oh, so very little time in which to do it.
Honestly, I'm still for getting married when we pick up our marriage license in August (if not sooner than that!). I love my friends and family, and am so thankful that they'll all be there to celebrate with us, but I'm over the idea of having a wedding; I just want to be married.
Phew, okay, now that I've said that out loud, I don't feel so badly.
On to things I CAN control for the most immediate results.
It takes, on average, 21 days to break a habit or build a new one.
For the next 21 days I will:
Drink 8 glasses of water a day, but aim for more.
If I start today (05/16/13) that will bring me to (06.06.13). Yikes! June is really that close?!
I will take the stairs UP to work. That's three flights of stairs if I start on the first floor. I will work up to taking the stairs from the basement. This hurts my knees, but it'll get better with time.
I will take better care of me. This means I will:
Make an appointment with my hair dresser to get my hair under control and discuss wedding hair. (I will do this by the end of the month, and aim for an appointment on June 5th).
Invest in a teeth whitening kit, and use it!
I will look into a spray tan package so that I start building a realistic looking tan before the wedding; nothing too tan, but enough to give me some healthy color-I currently blend into my wedding dress. I'd like to stand out instead.
I think these are reasonable goals for the next 21 days!
I got my eyebrows waxed for the first time in, two months (scary, I know!) the other day, and it's amazing how much better I feel when I look in the mirror. I want to keep feeling good about myself, and for DJ to be proud to be seen out and about with me. Well, that isn't quite true, he IS proud of me, but I want to feel comfortable and put together too.
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I generally improve my water consumption if I fill the designated "adult sippy" (lidded straw cup) with water early on in the day. Sipping and refilling seem to make use of old mindless munching habits.
Great list of wedding preparations, and hope it all turns out lovely. I've had good luck with the "daily" tanner/moisturizers. Every other day for 4 or 5 days seems to be a great look. I'd recommend trying one now, then watching how it fades to decide when you want to get slathered up for the big day.
Finally, I found myself here at your blog because I took a peek into the SparkPeople group of people who started the same week, back in Nov 2010. Wish I'd stuck with it the first time, wish I hadn't slacked off for 6 months recently, but still so very much better off than I was! Hope you feel the same.
1130 days ago
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Smokey BlueIts true! This special version of Oregon Blue Vein is cold smoked for 16 hours over Northwest -grown hazelnut shells. The result is a balance of sweet caramel and hazelnut flavors that contrasts deliciously with the sharp bite of the blue veining. Read More
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Opening Friday, January 24, CAT Theatre will present the world premiere of The Joshua Plant.
The Joshua Plant tells the story of Joshua, a teenage boy with autism, who sees the world in a way most people cannot imagine. This heartwarming, funny and suspenseful play explores the conflict between Joshua, his mother's boyfriend, and Joshua's best friend Sid, the family plant.
The Joshua Plant is CAT Theatre's 2014 contribution to the Richmond Acts of Faith Festival. As part of the Acts of Faith Festival there will be a special talk back sessions with the cast, director and authors following the performances on January 25 & February 2.
Written by Amy Berlin and P. Ann Bucci, The Joshua Plant was the winner of CAT's 50th Anniversary Original Play contest and was chosen from dozens of entries. The Joshua Plant began as a ten-minute play that was a finalist in the 2005 Chicago Dramatist Fall Ten Minute Workshop. Since then, it has had three developmental readings with Phoenix Theatre and a staged reading at the Pandora Festival, as well as a reading at the Richmond Public Library as part of the Richmond Writer's series. CAT Theatre is excited to be bringing the full production of The Joshua Plant to the stage for the first time.
The inspiration for The Joshua Plant began as Bucci watched the son of her friend stare at the ocean. Bucci says, "This teen is quite similar to Joshua; he also has autism and trouble communicating, but when he watched the ocean, he was so calm and at peace, that I began to wonder what it was he saw and felt that I couldn't see."
Berlin continues, "We both were fascinated by this idea and inspired enough to embark on a nearly decade-long journey to bring this story to the stage. Listening to our words come to life in rehearsal is just an amazing experience!"
CAT Theatre cautions that while The Joshua Plant has comedic moments and features a teenager as a principle character, harsh language and simulated violence may make the show unsuitable for pre-teens. Parents and teachers are advised to use their own discretion.
According to the Autism Society, 1 percent of the United States population of children ages 3-17 have an autism spectrum disorder. Autism is the fastest-growing developmental disability.
The Joshua Plant runs through February 9, 2014. CAT Theatre is located at 319 N. Wilkinson Road, Henrico, Virginia 23227.
For more information and for tickets visit the CAT Theatre website at www.cattheatre.com.


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So, Bottomless Brunch Is Legal After All, It Seems
As long as they don't overserve.
Good news follows the week's bad news about bottomless-booze brunches: It seems the practice is, in fact, legal, as long as the booze accompanies a meal and the restaurant doesn't overserve. A State Liquor Authority clarified the law for the NYC Hospitality Alliance: "There is a limited exception in the statute when the service of alcohol is incidental to the event, such as in the case of certain brunch specials." The weekend can be lost once more.


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The Delaware Department of Transportation has announced the closing of Route 1/I-95 northbound March 1-2 for the proposed bridge column.
The work will being at 11 p.m. Friday and will last until 7 a.m. on Saturday. Route 1 northbound will be closed after exit 165B/I-95 northbound to Wilmington and Philadelphia.
All traffic will be detoured to I-95 northbound and exit to Route 141 westbound, then back to I-95 southbound and return to Route 1 northbound. For more information and detours, visit DelDOT.org.
Location, ST | website.com


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The LINGUIST List is dedicated to providing information on language and language analysis, and to providing the discipline of linguistics with the infrastructure necessary to function in the digital world. LINGUIST is a free resource, run by linguistics students and faculty, and supported primarily by your donations. Please support LINGUIST List during the 2016 Fund Drive.
Conference Information
|Full Title:
|Inaugural European Conference on the Social Sciences 2013
|Short Title:
|Brighton, United Kingdom
|Start Date:
|04-Jul-2013 - 07-Jul-2013
|Melissa Choi
|Meeting Email:
|click here to access email
|Meeting URL:
|Meeting Description:
|The International Academic Forum in conjunction with its global partners is proud to announce the Inaugural European Conference on the Social Sciences, at the Thistle Hotel, Brighton, UK from July 4-7, 2013.
Hear the latest research, publish before a global audience, present in a supportive environment, network, engage in new relationships, experience the UK, explore London and the Southeast, and join a global academic community.
Theme: 'Society, Environment and Trust: Towards Sustainable Systems of Governance'
This year's conference will include a variety of presenters representing a wide range of social science disciplines, expressing divergent views, searching for common ground, and creating the synergies that can inspire multi-disciplinary collaborations. In developing these relationships among ourselves, the role of the social sciences is strengthened as we take our place at the table, along with scholars in the STEM disciplines (science, technology, engineering, and mathematics), in seeking solutions to the complex issues and problems of the 21st century. I sincerely hope that we will use this time together, not just for intellectual discovery and discourse, but to establish a common vision and to motivate each other to do our part in the creation of a sustainable world.
|Linguistic Subfield:
|Cognitive Science; Discourse Analysis; Sociolinguistics
|LL Issue:
|Calls and Conferences main page


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'Dogs finish strong, defeat Presbyterian 14-10
Fresno State scored the final seven goals of the game and was led by junior Kyleigh Westgarth's five goals.
Bulldogs wrap up season-opening home stand
All Fresno State women's lacrosse home games include free admission and free parking in the Red Lot.
Lacrosse Begins Camp with Improved Culture, Goals
The Fresno State women's lacrosse team began camp on Monday as it prepares for its season opener on Feb. 12.
'Dogs Cap Season With 129 Combined Academic All-MW Honors
Two of the department's 12 winter and spring sports - baseball and women's swimming and diving - scored 17 selections each.
Eighty-Six 'Dogs Honored to Academic All-MW Teams
Two of the department's 12 winter and spring sports - baseball and women's swimming and diving - scored 17 selections each.
2015 (Senior): Appeared in nine games, starting seven, prior to a wrist injury ending her Bulldog career ... finished career as Fresno State's career record holder in ground balls with 73 ... picked up eight ground balls ... won seven draw controls ... caused six turnovers ... finished with three points on one goal and two assists ... named to 2015 MPSF All-Academic team.
2014 (Junior): Made 12 starts in the midfield for the Bulldogs in her junior campaign ... recorded four goals and five points ... finished tied for first on the team with 22 groundballs ... added nine draw controls and eight caused turnovers ... posted a career-high four groundballs in the win over St. Mary's on April 10 ... added a season-best three draw controls against Marist on March 2 ... currently holds the Fresno State all-time groundball record with 65 in her career ... named Hardest Worker at the end of the year team banquet ... earned a place on the 2014 MPSF All-Academic team.
2013 (Sophomore): In her second season as a Bulldog, Cisneros played in all 15 games and started in 14 ... scored seven goals and recorded two assists ... totaled for nine points ... picked up a team-high 26 groundballs ... finished second on the team with 25 draw controls ... recorded a season-best six draw controls against La Salle, tying the third single-game record ... finished first on the team with 10 caused turnovers ... named Fresno State Midfielder of the Year at the end of the year team banquet.
2012 (Freshman): Appeared in every game and started 11 games ... scored nine goals and recorded three assists ... tallied 12 points on the season ... recorded 23 shots and 17 shots on goal ... won 19 draw controls and 17 ground balls ... caused three turnovers ... scored a season-high three goals against Long Island ... recorded six shots against New Hampshire ... won seven draw controls against Long Island.
High School: Four year letter winner in lacrosse at La Salle Catholic College Prep ... was defense second team all-league her freshman year ... midfield second team all-league her sophomore year ... in 2010 she earned first-team all-league and honorable mention All-American ... in 2011 she was awarded first team all-league and first team All-American.
Personal: Born November 25, in Oregon City, Ore. ... parents are Jean and Jim Cisneros ... has one older brother named Travis ... enjoys horseback riding and photography ... favorite athlete is Mary Lou Retton because she is small but had such an impact in her sport when no one thought she could ... biggest athletic thrill was beating UC Davis in double overtime sudden death ... is a representative on the Student Athlete Advisory Committee ... most admires her family because they have taught her so much and have supported her in everything she does ... also recruited by Navy, UC Davis and St. Mary's ... chose Fresno State because the team and the atmosphere was so welcoming.
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I have a 2D function $f:R\times R \rightarrow R$ that represents periodical axis-aligned spatial bumps at specific spatial periods (frequencies), like $f=\sin^2(2\pi \nu_1 x) \sin^2(2 \pi \nu_2 y)$. I expect the bump frequencies to be clearly visible as maximums on 2D Fourier transform of $F(kx,kx)= Fourier(f)$ at points $kx=2\pi\nu_1, ky=2\pi\nu_2$.
How does $F$ responds to the rotation of the $f$ around the origin? Would I see the maximums of the spatial frequencies on their correct places? Is there any other transformation that is invariant against the rotation and can show the spatially-periodic background of the function $f$?


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David Tousley
Ladies and gentlemen I Would like to introduce to you the "Future of Fitness" next time you see him in the gym on a Monday taking the CrossFit Kids class for a warm up and then the Level I class at 5pm give him a high 5 and yell HOORAA because this kid is a "Firebreather" At 10 years old David plays tackle football for the Scottsdale Firebirds and is in his 3rd week of playoffs with a record 0f 9-0. Having outscored thier oponents 369-0. We started working with him in January and now almost 10 months later all his off season prep work is paying off on and off the field. Both his parents Chris and Devra are also CrossFitter's, my families insurance agent and real estate broker, sister Lauren is a gymnast and they are the best neighbors I have ever had. David's semi final game will be this Saturday Vs the Gilbert Dawgs at 3pm at Chaparral High
Good luck David.


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Confirmed to include several new player skins from a variety of popular gaming franchises, 4J Studios continues to reveal new avatar options coming to the Xbox One and Xbox 360 editions of Minecraft with Skin Pack 6's release. Joining the list of licensed skins that are heading to the game, fans of the Undead Labs' Xbox Live Arcade zombie survival game are in for some good news after the developer announced on June 18 that the next skin pack DLC for Minecraft will feature new playable avatars based on State of Decay survivors.
Undead Labs shared with fans that Skin Pack 6 will offer gamers the opportunity to play Minecraft as iconic characters from the studio's popular zombie title. Included in the add-on are new Minecraft skins representing the first playable survivors from State of Decay's story campaign. Skin Pack 6 will also feature a skin based on State of Decay's well-known "Shark Hoodie Guy" in addition to the starter heroes of Marcus, Maya, and Ed.
The newly announced State of Decay avatar skins are the latest revealed additions of the skin pack DLC that will appear exclusively on Xbox editions of Minecraft. While the Xbox One version of the game won't release until later this summer, 4J Studios has alreadly confirmed that Skin Pack 6 will be available on the new console when the game launches.
Minecraft's next skin pack release will also feature new playable avatars from several other video game franchises in addition to characters from the Xbox Live zombie title. Included in the DLC will be skins representing characters from Killer Instinct, Trials Fusion, and Mirror's Edge: Faith with even more skins expected to be announced soon.
Despite the fact that Minecraft is out now on PS3 and coming soon to the PS4 and PS Vita, Skin Pack 6 will only be available on Microsoft platforms due to the add-on's inclusion of various characters from Xbox exclusive titles like State of Decay and Killer Instinct. A release date has not yet been announced for the new DLC.


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Aug 10, 2010 9:20 AM
For instant decadence that you can pull of no matter your decor, swap your boring white board for a Rococo ChalkBoard ($36). Whether you're sprucing up your kitchen or a dorm room, this detailed decal is sure to add a touch of elegance - and organization!
If you've got a product or service that you'd like to promote on Outblush, click here to find out about our advertising opportunities.
Outblush is a blog for girls who love to shop. Our staff digs up the best clothes, home stuff, beauty items, and more. New items are posted every day — bookmark us and check out:


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There's an old adage that disasters happen in threes, and today's (July 24) announcement of the disappearance of an Air Algerie MD-83 plane carrying 116 people from Burkina Faso to Algeria's capital seems to validate the premise. The newer occurrence comes on the heels of the disappearance in March of Malaysia Airlines Flight 370 and the recent crash of a second Malaysia flight in the Ukraine (both were Boeing 777s).
According to AOL on line and other Internet new sources, "the plane disappeared from radar early Thursday over northern Mali and "probably crashed," according to the plane's owner and government officials in France and Burkina Faso."
Algerian news agency APS reported that air navigation services lost track of the flight about 50 minutes after takeoff from Ouagadougou, the capital of Burkina Faso, at 0155 GMT.
It was also reported by APS that more than 50 French were onboard the plane, that was operated by Spanish airline Swiftair, along with 27 Burkina Faso nationals and passengers from a dozen other countries. The flight crew was Spanish. The last message heard from the pilot was around 0130 GMT (9:30 p.m. EDT), asking Niger air control to change its route because of heavy rains in the area, Burkina Faso Transport Minister Jean Bertin Ouedraogo said.
While the disappearance of Malaysia Airlines 370 remains a mystery, the downing of the carrier's plane in the Ukraine appears to be an act of terrorists who allegedly shot it down with a surface to air missile. In case you missed it, this week U.S. and European airlines began canceling flights to Tel Aviv after a rocket landed near the city's airport. Authorities, so far, do not suspect foul play in the disappearance of the Air Algerie flight. Algerian aircraft have been overflying the region around Gao to try to locate wreckage, said Houaoui Zoheir, spokesman for the Algerian crisis center.
According to Twitter tweets and Facebook postings it appears people are beginning to get jittery about flying, but that usually happens after air disasters as it does when cruise ships catch fire or sink.


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Walker's Pace: Tuesdays in Track Town Returns
Friday, February 25, 2011, 10:30 a.m.
The popular "Tuesdays in Track Town" series will make its 2011 debut this Tuesday (March 1) from 7 p.m. to 8 p.m. at the Bowerman Building on 15th Avenue.
The first gathering of the year will feature heptathlon world record-holder Ashton Eaton of Oregon Track Club Elite, collegiate pentathlon record-holder Brianne Theisen of the University of Oregon and 2011 Reebok Boston Indoor Games mile champion Russell Brown of OTC Elite.
Associate Athletic Director Vin Lananna will also discuss the March 4 single-meet ticket sales launch for the upcoming season, the 2011 USA Track & Field Championships, which Oregon is again hosting this June, as well as highlights from the current collegiate indoor season.
"Tuesdays in Track Town" is free and open to the public. Those attending are reminded that parking is free after 6 p.m. on 15th Avenue, as well as many of the University lots, but be certain to read parking lot signage carefully.
Future "Tuesdays in Track Town" meeting dates are set for April 5, May 3 and a yet-to-be-determined day in June.
Purchase 2011 Oregon Track & Field Tickets.
2011 Oregon Track & Field Multi-Media Guide.
Bookmark From the Press Box or subscribe to an RSS Feed for From the Press Box Blogs


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For the last reporting week of January mortgage rates fell seven basis points to 4.320%. The news came amidst reports from two standard industry housing metrics: New home sales and the Case Shiller index. Both reported numbers down and their impact was one factor for the rate decline.
The benchmark 30 Year mortgage fell as did the popular 15 year mortgage. The data is from the weekly lender survey as reported by secondary giant Freddie Mac (Federal Housing Loan Mortgage Corporation).
For the month rates retreated nearly 20 basis points, as they started 2014 at 4.530%. While rates do bounce around on a daily basis, numbers within 25 basis points are considered normal movement.
The President's minimum wage hike
President Obama's proposed minimum wage hike of $10.10 per hour to new federal workers, may be the life-line millions are looking for in becoming home owners. Of course if other private industries follow suite it could be a rippling affect for those previously shut out.
Housing remains the number one expense for consumers. Assuming one can achieve full-time employment and has decent credit there are programs which allow those on the lower income scale to experience "the American Dream." Yet for some, they may have to cobble together a combination of whatever income is available (as long as it is steady) to meet mortgage qualifying standards, which are based on monthly gross.
As an example based on the new $10.10 hourly rate, which translates into $400 per week or $2,100 per month, a mortgage payment including taxes and insurance of $685 is achievable. Based on current rates, that will yield home prices up to the $90,000 range. For some finding such properties would be like finding a "needle in a haystack" for the many, given the decline in home prices there is plenty of available stock.


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Weusthuis Named UMass Athlete Of The Week
Oct. 1, 2012
AMHERST, Mass. - UMass field hockey freshman defender and midfielder Noralie Weusthuis was named the UMass Athlete of the Week on Monday afternoon. Weusthuis recorded her first collegiate goal on Sunday against No. 24 Maine in UMass' 4-2 victory - their fourth win over a ranked opponent this season.
When facing No. 24 Maine, Weusthuis placed home the third goal of the game against the Black Bears in the two-goal win. Weusthuis' tally marked the eventual game-deciding goal, as Maine went on to rally for a pair of scores late in the contest.
A native of the Netherlands, Weusthuis has started each of the 11 field hockey contests this season, spending time on defense and midfield during her rookie campaign. Weusthuis currently owns three points, including the recent goal and an assist during UMass' 10-1 win over Vermont.
Weusthuis is the second field hockey player to be honored as the UMass Athlete of the Week this season, joining senior midfielder Kim Young, who was honored with the laurel on Sept. 4. The Minutewomen continue their season with a game against No. 5 Connecticut at Garber Field on Wednesday, Oct. 3 at 6 p.m.
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At first it was ancient wisdom which stated that we are one with the universe, that everything is interconnected, that all is one.
Then later modern science caught up with this idea. Now quantum physicists say exactly the same thing – in a subatomic level everything is interconnected.
In the 1970s chemist James Lovelock formulated the famous Gaia hypothesis which proposes that all organisms and their inorganic surroundings on Earth are closely integrated to form a single and self-regulating complex system, maintaining the conditions for life on the planet.
Everyone is talking about the same idea, only from different perspectives. We add one more – a visual perspective.
This symbol is presented like a metaphor of us and our earth. It is a big organism and we, people, are parts of this organism; we are not separate. And the earth is also just a part of an even bigger organism. Our earth is like a tree with roots that extend to the vast cosmos. Everything is interconnected.
A human being is a part of the whole called by us universe, a part limited in time and space. He experiences himself, his thoughts and feeling as something separated from the rest, a kind of optical delusion of his consciousness. This delusion is a kind of prison for us, restricting us to our personal desires and to affection for a few persons nearest to us. Our task must be to free ourselves from this prison by widening our circle of compassion to embrace all living creatures and the whole of nature in its beauty."
– Albert Einstein
You and I are all as much continuous with the physical universe as a wave is continuous with the ocean."
– Alan Wilson Watts
Gaia Democratic School admits students of any race, color, religion, gender, disability, sex, sexual orientation, gender expression, national and ethnic origin to all the rights, privileges, programs, and activities generally accorded or made available to students at the school. GDS does not discriminate on the basis of race, color, religion, gender, disability, sex, sexual orientation, gender expression, national or ethnic origin or any other reason.


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Dave Christensen Announces New Coaching and Administrative Responsibilities for Wyoming Football Staff
Jamar Cain, Jason Gesser and Nick Danielson Join Cowboy Staff as Assistant Coaches
Wyoming Cowboys Host Toledo Rockets in 2012 Home Opener
Saturday's Matchup Will Feature Two Bowl Teams From 2011
Wyoming Cowboys Host Toledo Rockets in 2012 Home Opener
Saturday's Matchup Will Feature Two Bowl Teams From 2011
Derrick LeBlanc Hired as a Defensive Line Coach at Wyoming
Head Coach Dave Christensen announces new coaching staff duties.
Gold Team Defeats White Team 20-7 as Wyoming Football Completes 2012 Spring Drills
Wide Receiver Dominic Rufran Leads Gold Team With Six Receptions for 112 Yards
Gregg Brandon returned to the University of Wyoming Football program in 2011 to lead the Cowboy offense as offensive coordinator and quarterbacks coach. He will be entering his 31st season as a college coach in 2012. In his first year back at UW, the former Cowboy assistant coach and former Bowling Green head coach mentored 2011 Mountain West Conference Freshman of the Year Brett Smith at quarterback. Smith ranked No. 2 in the Mountain West Conference and No. 33 in the nation in total offense and earned First Team Freshman All-America honors from CollegeFootballNews.com.
With Brandon coordinating the Cowboy spread offense, the Pokes ranked No. 33 in the nation in rushing offense, averaging 181.6 yards per game. Wyoming also ranked No. 4 in the Mountain West in both rushing and passing offense (206.8 yards per game). Brandon's 2011 offensive unit was extremely effective at protecting the ball and limiting turnovers. UW's offense ranked No. 20 in the nation in fewest fumbles lost (8) and No. 32 in the NCAA in fewest total turnovers lost (19). He helped guide the Cowboys to the 2011 Gildan New Mexico Bowl, which marked his 10th bowl appearance as a coach in his 30 years as a college coach.
Brandon was the head coach at Bowling Green from 2003-08. During that six-year span, he led the Falcons to three bowl appearances and four winning seasons, including an 11-3 season in 2003, a 9-3 mark in 2004 and an 8-5 campaign in 2007. He won 60 percent of his games as a head coach, posting a head-coaching record of 44-30 at BGSU. In four of his six seasons as head coach, his teams averaged over 400 yards of total offense. Bowling Green defeated Northwestern in the 2003 Motor City Bowl, defeated Memphis in the 2004 GMAC Bowl and played Tulsa in the 2007 GMAC Bowl. The Falcons also earned a berth in the 2003 Mid-American Conference Championship game. His teams at Bowling Green recorded impressive non-conference wins: at Purdue (27-26 in 2003); at Minnesota (32-31 in 2007) and at Pittsburgh (27-17 in 2008). Bowling Green had 33 All-MAC selections and one MAC Player of the Year (Omar Jacobs in 2004) during Brandon's time at BGSU.
"I've known Gregg Brandon for a long time," said UW head coach Dave Christensen. "When we decided to implement the spread offense at Missouri, the person I contacted to teach our staff the spread was Gregg. He is one of the foremost experts on this offense in the country. He served as Urban Meyer's offensive coordinator at Bowling Green prior to becoming the head coach there for six seasons. Gregg, of course, also has ties to Wyoming. He coached here for four seasons with Coach (Paul) Roach, during one of the most successful periods in Wyoming Football history."
"I'm really excited to be back at the University of Wyoming," said Brandon. "I have great memories from here. As all Poke fans know, from `87-'90 we had a great run with back-to-back WAC Championships in `87 and `88 and a 16-0 run in conference. Those were great teams and working for Paul Roach was a tremendous experience. I learned so much football from him.
"I think this is a new era for Wyoming Football with Dave (Christensen). Dave and I have a history from when he was at Missouri and I was at Bowling Green. During those years, we had the opportunity to share ideas and share our offensive philosophies. To now be able to coach with him at a place like Wyoming that has great tradition and is a place where we can get great players and compete for a Mountain West Championship is about everything a coach can ask for. And at the same time to live in a great football community and state like Wyoming, I couldn't be happier."
Brandon's 2004 Falcon team set school and Mid-American Conference records for total offense (averaging 506.3 yards per game to rank No. 2 in the country) and scoring offense (averaging 44.3 points per game to rank No. 4 in the NCAA). That 2004 squad also averaged 338.3 passing yards per game to rank No. 3 in the nation, and had a pass efficiency rating of 165.5, ranking No. 4 in the country. His sophomore quarterback,Omar Jacobs, earned All-America honors, led the nation in touchdown passes with 41 and set an NCAA record for touchdown to interception ratio, throwing only four interceptions compared to his 41 TD passes during the `04 season. Bowling Green defeated Memphis, 52-35, in the 2004 GMAC Bowl.
In his first season as a head coach in 2003, Brandon guided the Falcons to a No. 23 national ranking in both the final Associated Press Poll and USA Today Coaches' Poll. Bowling Green was also ranked No. 24 in the 2003 final BCS standings, and was ranked for a school record eight consecutive weeks. The Falcons captured the Mid-American Conference West Division. BGSU's 2003 offense averaged 496.7 yards of total offense per game to rank No. 3 in the nation, 300.4 passing yards to rank No. 9 in the NCAA and 33.6 points per game to rank No. 20. Bowling Green concluded the season with a 28-24 win over Northwestern in the Motor City Bowl.
He was originally hired as Assistant Head Coach and Offensive Coordinator at Bowling Green in 2001 by Urban Meyer. In his two years in that position, he helped the Falcons post a combined 17-6 (.739) record. His 2002 offense ranked No. 3 in the NCAA in scoring offense (40.8 points per game), No. 8 in total offense (448.9 yards per game) and 15th in rushing (219.1 yards per game). BGSU broke 17 school records and seven MAC records that season.
From 1987-90, Brandon was the wide receivers' coach at Wyoming under head coach Paul Roach. During that four-year span, Wyoming won back-to-back Western Athletic Conference Championships in 1987 and `88 and went undefeated in conference play both years. The Cowboys appeared in the 1987 and 1988 Holiday Bowls. In 1990, UW earned an appearance in the Copper Bowl. Wyoming's combined record during Brandon's time as an assistant was 35-15-0 for a winning percentage of .700, and included records of 10-3 in 1987, 11-2 in 1988 and 9-4 in 1990.
After coaching at UW, Brandon was an assistant coach at Utah State (1991), Northwestern (1992-98), Colorado (1999-2000) and Bowling Green (2001-02), before serving as the head coach at Bowling Green (2003-08). In 2009, he was the offensive coordinator at Virginia, and in 2010 he was on the coaching staff of the Las Vegas Locomotives of the United Football League (UFL).
During his college career, he has helped lead nine teams to bowl appearances, including an appearance in the Rose Bowl at the conclusion of the 1995 season while coaching at Northwestern. Northwestern won the Big Ten title outright in 1995, and tied for the conference championship in 1996.
A native of Colorado Springs, Colo., he played his first year (1974) of college football at Mesa State in Grand Junction, Colo., before transferring to Northern Colorado where he played his final three seasons (1975-77) as a defensive back and wide receiver. He graduated from UNC in 1978 with a bachelor's degree in education.
He and his wife, Robyn, have two sons, Nick and Tim. Brandon will recruit the state of Colorado for the Pokes.


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Posts tagged "cycle in cinema"
February 21st, 2012
Cycle In Cinema
Categories: Entertainment and Sydney. Tags: cycle in cinema, cycling, and taylor square.
Imagine a drive-in cinema with bikes instead of cars. Fixies instead of Falcons. Where you go tandem, not shotgun. Turns out the peeps at Magnificent Revolution (cool name, ...Read more


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It's been a gradual change of seasons with lots of things going on on the Outer Banks. I've participated in the Outer Banks Triathlon as a member of a relay team – I did the bike portion: 13.1 miles starting at the Dare County Regional Airport over the old Manns Harbor Bridge and back. The ride out was smooth and the views were spectacular, but when I made the turn at Mashoes Road, I hit a wall of wind and it took everything in me to get back across the bridge.
This weekend marked the First Annual Bluegrass Festival at Festival Park in Manteo. This was a sell-out event. Unfortunately I didn't get to go, but it's on my calendar for next year. Check out some great photos on Facebook at https://www.facebook.com/OBXBluegrassFestival?fref=ts.
Today marked the 6th Annual Duck Jazz Festival, featuring The Rippingtons with Russ Freeman, Paula Atherton, THE FUZZ BAND, and Emme St. James and Her Jazz Gentlemen.
Today also marked the final day of the 20th Annual Outer Banks Home Builders Parade of Homes. The homes were selected featuring new designs and many incorporate new technologies, best building practices and 'green' features.
There is a plethora of events and activities coming up. My favorite resource for all things is http://www.outerbanks.org/outerbanks-events/.
My favorites include:
- The Colony Lost & Found 5K and Fun Run, October 13 in Manteo
- Outer Banks Seafood Festival, October 20 in Nags Head
- Trick or Treat Under the Sea, October 24 at the Roanoke Island Aquarium
- Outer Banks Marathon, including Half Marathon, 8K, 5K, Southern 6 & more, November 9 – 11
It's a beautiful time of the year to visit the Outer Banks!


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Sideshow Collectibles Pre-Orders
Angry Birds Star Wars
Foam Flyers (Set of 4)
12" Jumbo Figures
Animated Maquettes
Boxed Vehicles & Playsets
AFA Figures
Classics Carded
Classics Carded
Regarding MTMTE #54, not with the fakeout deaths again???!!!figrin bran 12 Hours Ago
You can find it on Youtube. The version I watched was broken up into 6 parts and each part was about 45 minutes long. So it's pretty in depth. In fact,bigbarada 15 Hours Ago
This 2016 series was okay, but it doesn't have a different title, just SW Evolution like the 2001 one: text was interesting (how characters, well, evolvedBel-Cam Jos 18 Hours Ago
A little late, but Romper Room children's show actress Mary Ann King, at 82. :magicmirror:Bel-Cam Jos 20 Hours Ago
I enjoy (but in all honesty, do not love) watching international futbol, but a nil-nil end to a championship match always leaves me feeling a bit empty.Bel-Cam Jos 21 Hours Ago
Are Rogue 1 sets coming? Found this info on a German website.
BigBarada, thank you for your service and thank you for sharing. It would be very interesting to get a better understanding of the circumstances in YugoslaviaTycho 1 Day Ago
At about 7000 pgs. with the 27 books read as of today...
Big Sky Summer by Linda Lael Miller. For this summer's library book program, one
Independence Day: Resurgence. Not a bad action/sci-fi flick. It had a different feel than the original. Maybe if the producers hadn't waited 20 years?OC47151 1 Day Ago
That's both cool and sad, BB. On PBS lately, they've had Ken Burns' National Parks documentaries showing, and I enjoy seeing places I've been before (butBel-Cam Jos 1 Day Ago


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When the term "flautist" came along — 1860, according to Merriam-Webster — the traditionalists, that bunch who'd been using "flutist" since 1603, may have been alarmed. Baltimore-native Candie Cramer falls into the latter bunch, those preferring "flutist." At least, that's the phrase she uses to describe herself.
Candie Cramer
Arguably, she is something of a traditional person, having recorded a CD dedicated to Christmas music.
"It's such a classy, elegantly done CD of Christmas music," she says of A Candie Cramer Christmas, including her flute renditions of old chestnuts such as O Come, All Ye Faithful and Silent Night. But she's also mixed things up a bit with newer offerings including Christmastime is Here and Santa Baby. That's not the limit of Cramer's challenge to tradition, however. After all, how many traditional flutists are transgendered?
"I'm not aware of any other transgendered flutists who are actively performing classical or R&B," offers Cramer, who studied at the Oberlin Conservatory of Music. "I've had extremely good training."
But Cramer's identity is one of few non-traditional twists when it comes to her Christmas sensibilities. Her Christmas joy is downright homespun.
"It's a very special time for me. It's also the time of year my parents gave me my first flute. It was a used flute, but it was very shiny and very special to me."
Following the tradition of many modern Americans, Cramer says that while Christmas is special, it can also be emotionally taxing. She says it may leave her thinking about the birth of Christ on one hand, but of family members who have died on the other, particularly her sister, Geraldine, who died in 2001.
"We were a very tight-knit family and Christmas was the most tightly knit time of year," remembers Cramer, 43, who will be spending this Christmas with her surviving brother's family, and Geraldine's daughter, Christina, to whom Cramer is offering any proceeds from this CD. "The holidays are very difficult for me, but music helps me get through."
A Candie Cramer Christmas is available at Lambda Rising bookstores in D.C., Baltimore and Rehoboth, and online at www.fluteworld.com.
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Alice in Wonderland Adventure Party (23 photos)
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For my daughter's 6th birthday I threw her an Alice in Wonderland party. The party took her and the guests through each scene in the classic Disney movie to help Alice find her way back out of Wonderland and home to eat her cake! As always with my parties I am on a budget and make everything myself.
My daughter was Alice. My son dressed up as a playing card, my youngest daughter as the Queen of hearts, my husband as the Mad hatter, my mother as the cheshire cat, my two friends who helped with the party as Tweedle dum and Tweedle Dee and myself as the White rabbit. When they arrived they had to crawl through a giant "rabbit hole" to enter our house (we drew a giant tree and hung it from our front door with a small "rabbit's hole" to the side for them to crawl through). There was a giant White rabbit to the side of the tree with a huge pocket watch. When they crawled through they came into our entryway where tables were set up to make their own Mad hatter hat (there were bunny ears, mouse ears, string, stickers, paint and colors to decorate them with). When they were done with their hats we went back outside and took a group picture with everyone's hat on.
Then they came back in and the adventure began! On a little table in the entrance way they found an eat me cookie and a drink me bottle to drink. They ate and drank to get to the right size and then they crawled through a miniature door we had drawn and hung on some curtains in our entrance way. Then they went into the first room where they recieved a goodie bag with a tea pot on it to collect their favors along the way and then there was a caucas race (musical chair type game but with Alice characters taped to the ground). Then they moved to the next room where Tweedle Dum and Tweedle Dee told them the story of Alice. Then we went to the flower garden (there were giant paper flowers in real pots all over the room) where they made their own flower pots with a flower in it with a picture of themselves glued to the flower. Then we visited the Cheshire cat and played pin the grin on the cheshire cat. Then they went to the Mad Hatter's tea party and had dinner. The food and drinks were all served in tea cups and pots. I made little Mad Hatter hats for place cards with their names on them. There were heart shaped pizzas, card sandwiches, pocket watch crackers with cheese and other snacks. They drank tea in real tea cups and poured it themselves. After that we divided the girls up and one group went to play flamingo croquet with the Queen and the other played Don't be caught with the roses (fake white roses dipped in red paint and played like hot potato). There were giant inflatable flamingos for the kids and little hedgehog balls and they shot them through giant playing cards I had made from poster board. The groups switched and then we officially made it out of Wonderland, away from the Queen of Hearts and had cake- a Topsy Turvy cake- and presents.
For favors the kids brought home their flower pot which we filled with candy once they had dried, and a goodie bag with a flower ring, a pack of hearts cards with a white rabbit on the front, a shell from the caucas race and their mad hatter place card.
It was a great adventure and the kids had a lot of fun!


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Stock Upgrades: Zynga Can Draw Comfort From Wall Street
Justin Sharon
Wall Street ratings agencies set the tone for today's stock market.
, and Anthony's
, each endured days to forget, but elsewhere it was high-fives all around for investors, with the
S&P 500 Index
(INDEXSP:.INX) advancing for a seventh straight session. The company co-created by Steve Jobs slid 5.44% as a
rash of ratings reductions
, illustrated how far the firm has fallen from its historic high last September. That same month, it turns out, marked the nadir for
(NASDAQ:FB), but its torrid times from 12 months ago are now but a nasty nightmare. Shares surged a further 3.30% to an all-time peak amid speculation that a trip to China by its COO hints at something big. Let's hope so. The last time such fevered speculation accompanied one of the company's key executives abroad, it turned out
Mark Zuckerberg only journeyed to Hungary to check out its dogs
. If Sheryl Sandberg is merely blazing the same tease-worthy trail in Shanghai, she will be in some serious Shih Tzu.
In today's earnings action,
Brady Corp
Lululemon Athletica
NetSol Technologies
(NASDAQ:NTWK), and
Ulta Salon
(NASDAQ:ULTA) are all due to report results.
(NYSE:ALL): Citing a favorable industry backdrop, Wells Fargo moves the insurance outfit to Outperform from Market Perform.
Cardinal Financial
(NASDAQ:CFNL): Shares get upgraded to Outperform from Perform at Keefe Bruyette. The price objective, previously $18, increases to $20.
Cash America
(NYSE:CSH): JMP Securities increases the equity to Outperform from Market Perform.
Constant Contact
(NASDAQ:CTCT): The marketing services name is now Buy from Neutral at Janney.
EnCana Corporation
(NYSE:ECA): RBC Capital Markets raises the oil and gas company to Outperform from Sector Perform.
Harmony Gold Mining
(NYSE:HMY): JPMorgan hoists the commodity company to Overweight from Neutral.
(NASDAQ:PLCM): The video conferencing company gets taken to Outperform from Market Perform at Raymond James.
Portland General Electric
(NYSE:POR): KeyBanc gives the utility a Buy-from-Hold boost.
(NASDAQ:WEN): The fast food firm is hoisted to Buy from Hold with a $10 target at Argus, which has high hopes for both better value offerings and restaurant remodeling.
Zynga Inc
(NASDAQ:ZNGA): Evercore increases the gaming company, whose offerings include
Draw Something
, and
Words With Friends
, to Equal Weight from Underweight. Reasons for optimism include increasing user engagement and shares are, accordingly, showing strength ahead of today's opening bell.
(See also:
New Stock Coverage: Rock-Tenn, Paper Stock, Beats Scissors
Stock Downgrades: Is Netflix Revenue Stream Up a Creek?
No positions in stocks mentioned.
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Permanent URL to this publication: http://dx.doi.org/10.5167/uzh-60446
Käppeli, U; Hächler, H; Giezendanner, N; Cheasty, T; Stephan, R (2011). Shiga toxin-producing Escherichia coli O157 associated with human infections in Switzerland, 2000-2009. Epidemiology and Infection, 139(7):1097-1104.
|Published Version
View at publisher
SUMMARY: Shiga toxin-producing Escherichia coli (STEC), an important foodborne pathogen, can cause mild to severe bloody diarrhoea (BD), sometimes followed by life-threatening complications such as haemolytic uraemic syndrome (HUS). A total of 44 O157 strains isolated from different patients from 2000 through 2009 in Switzerland were further characterized and linked to medical history data. Non-bloody diarrhoea was experienced by 15·9%, BD by 61·4% of the patients, and 29·5% developed HUS. All strains belonged to MLST type 11, were positive for stx2 variants (stx2 and/or stx2c), eae and ehxA, and only two strains showed antibiotic resistance. Of the 44 strains, nine phage types (PTs) were detected the most frequent being PT32 (43·2%) and PT8 (18·2%). By PFGE, 39 different patterns were found. This high genetic diversity within the strains leads to the conclusion that STEC O157 infections in Switzerland most often occur as sporadic cases.
11 citations in Web of Science®
8 citations in Scopus®
Google Scholar™
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|Item Type:
|Journal Article, refereed, original work
|Communities & Collections:
|05 Vetsuisse Faculty > Institute of Food Safety and Hygiene
|Dewey Decimal Classification:
|570 Life sciences; biology
610 Medicine & health
|Deposited On:
|17 Mar 2012 20:15
|Last Modified:
|05 Apr 2016 15:42
|Cambridge University Press
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|Copyright: Cambridge University Press.
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Date: Tuesday, October 23, 2012
Adalisa came right to the right place. She was looking a Fiesta and she found one! Of course the password didnt change so her showing us her juicy perky tits was a MUST. After she passed the test with flying colors it was time to show Adalisa what the fiesta was all about. She would sure not be disappointed!


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2 May 08:04 2008
Nicolas Dudfield's GSoC project
Laura Creighton <lac <at> openend.se>
This showed up on the pygame mailing list. Nicolas cc'd here. ------- Forwarded Message Greetings all, I am a participant in the Google Summer of Code. My application for writing tests for pygame was accepted. The goal, over and above having tests for their own sake, is to make pygame easier to port to new and different platforms and versions of Python. Py3k is due soon, and people have all sorts of ideas for pygame, such as deploying on flash VMs using pypy. Really cool ideas. All of this will be made much easier with more extensive testing in place. A rough estimate for current unittest coverage is about 20%. Ideally, at least 95% would be covered. A brief outline =============== 1. Write unittests for pygame 2. Develop a speed regression framework 3. Develop an interactive testing framework. 1) Write unittests for pygame ============================== Being a student, the fact is that I don't have that much experience(Continue reading)