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Chapter 5. Hormones and the Brain
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Melatonin is marketed as a natural sleep aid but it's potentially risky for healthy children to use long term, Canadian pediatricians say. Difficulties settling, falling asleep and staying asleep affect up to 25 per cent of children generally and up to half of those with physical and mental health problems, according to the Canadian Sleep Society. Melatonin is a hormone of darkness that is part of the sleep cycle. People can buy melatonin supplements at pharmacies and health food stores to overcome jet lag or occasional insomnia. But long-term use by healthy, developing children isn't advised, said Dr. Shelly Weiss, a neurologist at the Hospital for Sick Children in Toronto, who is studying the use of melatonin supplements for improving sleep in children with epilepsy. "It's being touted as this magic pill," said Weiss. "There's definitely concern that people are going to use it more widely and not appreciate that their child can learn to sleep better without a hormone being given." Melatonin supplements contain between 25 to 50 times as much melatonin as the body makes at night, Weiss noted. "There's definitely potential risk, mostly to delayed puberty or delayed development in children who have taken it for a long time," said Weiss, who is also president of the Canadian Sleep Society and an associate professor at the University of Toronto. © CBC 2013
Keyword: Sleep; Hormones & Behavior
Link ID: 18354 - Posted: 07.08.2013
A randomized clinical trial of estrogen therapy in younger postmenopausal women, aged 50–55, has found no long-term risk or benefit to cognitive function. The National Institutes of Health-supported study, reported in JAMA Internal Medicine on June 24, 2013, looked at women taking conjugated equine estrogens, the most common type of postmenopausal hormone therapy in the United States. The earlier Women's Health Initiative Memory Study (WHIMS) linked the same type of hormone therapy to cognitive decline and dementia in older postmenopausal women. The new findings come from the Women's Health Initiative Memory Study of Younger Women (WHIMSY) trial and were reported by Mark A. Espeland, Ph.D., Wake Forest School of Medicine, Winston-Salem, N.C., on behalf of the academic research centers involved in the study. The study was funded primarily by the National Institute on Aging (NIA), along with the National Heart, Lung, and Blood Institute (NHLBI), both components of the NIH. "The WHIMS study found that estrogen-based postmenopausal hormone therapy produced deficits in cognitive function and increased risk for dementia when prescribed to women 65 and older," said NIA Director Richard J. Hodes, M.D. "Researchers leading the WHIMSY study wanted to expand on those results by exploring the possibility of a window of opportunity whereby hormone therapy might promote or preserve brain health when given to younger women." "In contrast to findings in older postmenopausal women, this study tells women that taking these types of estrogen-based hormone therapies for a relatively short period of time in their early postmenopausal years may not put them at increased risk for cognitive decline over the long term," said Susan Resnick, Ph.D., chief of the Laboratory of Behavioral Neuroscience, in NIA's Intramural Research Program and a co-author of the study. "Further, it is important to note that we did not find any cognitive benefit after long-term follow-up."
Keyword: Hormones & Behavior; Alzheimers
Link ID: 18310 - Posted: 06.25.2013
By Brigid Schulte, Unlike the male pundits, politicians and even financiers who've opined freely recently about what they consider "natural" roles for mothers and fathers, with mom at home and dad at work, behavioral neuroscientist Kelly Lambert's methodical approach has led her to a much more complicated conclusion. From her perch at Randolph-Macon College in rural Ashland, Va., Lambert has spent years designing elaborate experiments to test nurturing in both male and female rodents. She anesthetizes the animals, carefully removes their brains, firms the brains up with formalin, freezes them, then shaves them into slices thinner than a strand of human hair to study under a microscope. What Lambert's rodent brain slices are revealing is nothing short of revolutionary, challenging the loud pundits and long-held cultural views that only mothers are wired for nurture. Lambert, one of a small but growing number of scientists who study the biology of father behavior, is finding that not just mothers experience surges of hormones associated with bonding and nurturing. The same hormones increase, though not to the same degree, in fathers. Rat mothers are not the only ones whose brains become sharper, making them more efficient foragers and more courageous and level-headed than females without offspring. Lambert has found that the same is true of fathers' brains. Fatherhood makes the male California deer mouse smarter, too. © 1996-2013 The Washington Post
Keyword: Sexual Behavior; Hormones & Behavior
Link ID: 18282 - Posted: 06.17.2013
By Breanna Draxler Is it a coincidence that the word vole is an anagram of love? Probably so, but since prairie voles mate for life, they have since been designated as the unofficial species used to study monogamy in lab animals. And a new study finds that their rare partnerships are cemented by chemical changes on their genes, called epigenetic changes, that result from their sexual encounters. When a prairie vole (Microtus ochrogaster) finds a mate, the two form a strong bond. Not only do they stay together for life and share child care duties, but the lovers will guard their mates aggressively against voles of the opposite sex. Scientists knew from previous studies that this bonding was regulated by neurotransmitters—chemical communicators in the brain such as oxytocin, which is linked to sex and reproduction, and vasopressin, associated with social recognition. However researchers were unsure what the biological basis was for such a sharp behavioral shift after mating. To find out, scientists at Florida State University paired up virgin male and female voles and gave the couples a cage together for a number of hours. Some couples were allowed to mate while others were prevented from doing so. The non-mating female voles instead received drug injections in the nucleus accumbens, a part of the brain's pleasure center. The drugs affected the voles' epigenetics by unwinding their DNA so that genes for vasopressin and oxytocin receptors were more highly transcribed.
Keyword: Sexual Behavior; Hormones & Behavior
Link ID: 18237 - Posted: 06.06.2013
A patient at the Kwong Wah and Queen Elizabeth Hospitals discovered he was also a woman when he came for treatment for a swelling abdomen. Photo: Nora Tam A 66-year-old apparently male patient made a stunning discovery when he sought treatment for swelling in his abdomen. The swelling was a cyst on his ovary and he was in fact a woman. The condition was caused by a very rare combination of two genetic disorders. One, Turner syndrome, causes women to lack some female features, including the ability to get pregnant. Sufferers usually look like women, but in this case the patient also had congenital adrenal hyperplasia (CAH), which boosted the male hormones and made the patient look like a man. The case was reported by doctors from Kwong Wah Hospital and Queen Elizabeth Hospital, who treated the patient. It was published in the Hong Kong Medical Journal yesterday. "The patient, by definition, is a woman who cannot get pregnant. But she also has CAH, which gave her the appearance of a man," Chinese University paediatrics professor Ellis Hon Kam-lun said. "It's an interesting and very rare case of having the two combinations. It probably won't be seen again in the near future." The 66-year-old Vietnam-born Chinese man is an orphan. He has a beard, small penis and no testes. Just 1.37 metres tall, he has decided to continue perceiving himself as a male and may receive male hormone treatment, the report said. © 2013 South China Morning Post Publishers Ltd
Keyword: Sexual Behavior; Hormones & Behavior
Link ID: 18236 - Posted: 06.06.2013
By ANAHAD O'CONNOR The number of middle-aged men with prescriptions for testosterone is climbing rapidly, raising concerns that increasing numbers of men are abusing the powerful hormone to boost their libidos and feel younger, researchers reported on Monday. Testosterone replacement therapy is approved specifically for the treatment of abnormally low testosterone levels, a condition called hypogonadism. The hormone helps build muscle, reduce body fat and improve sex drive. But a study published in the journal JAMA Internal Medicine found that many men who get prescriptions for the hormone have no evidence of a deficiency at all. The new study is the largest of testosterone prescribing patterns to date, involving nearly 11 million men who were tracked through a large health insurer. The report showed that the number of older and middle-aged men prescribed the hormone has tripled since 2001. Men in their 40s represent the fastest-growing group of users. About half of men prescribed testosterone had a diagnosis of hypogonadism, and roughly 40 percent had erectile or sexual dysfunction. One third had a diagnosis of fatigue. The medical group that sets clinical guidelines for testosterone replacement therapy, the Endocrine Society, recommends treatment only in men who have unequivocally low testosterone levels. That finding requires a blood test. But the new report found that a quarter of men did not have their levels tested before they received the hormone. It was also unclear what proportion of men who did undergo testing actually had results showing a deficiency. Copyright 2013 The New York Times Company
Keyword: Hormones & Behavior
Link ID: 18228 - Posted: 06.04.2013
Zoe Cormier Love really does change your brain — at least, if you're a prairie vole. Researchers have shown for the first time that the act of mating induces permanent chemical modifications in the chromosomes, affecting the expression of genes that regulate sexual and monogamous behaviour. The study is published today in Nature Neuroscience1. Prairie voles (Microtus ochrogaster) have long been of interest to neuroscientists and endocrinologists who study the social behaviour of animals, in part because this species forms monogamous pair bonds — essentially mating for life. The voles' pair bonding, sharing of parental roles and egalitarian nest building in couples makes them a good model for understanding the biology of monogamy and mating in humans. Previous studies have shown that the neurotransmitters oxytocin and vasopressin play a major part in inducing and regulating the formation of the pair bond. Monogamous prairie voles are known to have higher levels of receptors for these neurotransmitters than do voles who have yet to mate; and when otherwise promiscuous montane voles (M. montanus) are dosed with oxytocin and vasopressin, they adopt the monogamous behaviour of their prairie cousins. Because behaviour seemed to play an active part in changing the neurobiology of the animals, scientists suspected that epigenetic factors were involved. These are chemical modifications to the chromosomes that affect how genes are transcribed or suppressed, as opposed to changes in the gene sequences themselves. © 2013 Nature Publishing Group
Keyword: Sexual Behavior; Epigenetics
Link ID: 18221 - Posted: 06.03.2013
By Scicurious Aging happens. As you get older, your body slows down, eventually your brain slows down, too. Some things go gradually, and some go suddenly. To many people, this might seem like a pretty random process. We used to think of aging this way, as just…well cells get old, which means we get old, too. DNA replication after a while starts making errors in repair, the errors build up, and on the whole body scale the whole thing just kind of goes downhill. It seems random. But in fact, it's not. There are specific proteins which can help control this process. And one of these, NF-kB, in one particular brain region, may have a very important role indeed. NF-kB (which stands for nuclear factor kappa-light-chain-enhancer of activated B cells, which is why we use NF-kB) is a protein complex that has a lot of roles to play. It's an important starting player in the immune system, where it helps to stimulate antibodies. It's important in memory and stress responses. NF-kB is something called a transcription factor, which helps to control what DNA is transcribed to RNA, and therefore what proteins will eventually be produced. Transcription factors, as you can see, can have a very large number of functions. But in the hypothalamus, NF-kB may have the added function of helping to control aging. The hypothalamus is an area of many small nuclei (further sub areas of neurons) located at the base of the brain. It's been coming more and more into vogue lately among neuroscientists. In the past, we were interested in the hypothalamus mostly for its role in controlling hormone release from the dangling pituitary gland before it, but now we are learning that the hypothalamus can play roles in fear, mood, food intake, reproduction, and now…aging. © 2013 Scientific American
Keyword: Development of the Brain; Hormones & Behavior
Link ID: 18152 - Posted: 05.14.2013
Jo Marchant People with genes that make it tough for them to engage socially with others seem to be better than average at hypnotizing themselves. A study published today in Psychoneuroendocrinology1 concludes that such individuals are particularly good at becoming absorbed in their own internal world, and might also be more susceptible to other distortions of reality. Psychologist Richard Bryant of the University of New South Wales in Sydney and his colleagues tested the hypnotizability of volunteers with different forms of the receptor for oxytocin, a hormone that increases trust and social bonding. (Oxytocin's association with emotional attachment also earned it the nickname of 'love hormone'.) Those with gene variants linked to social detachment and autism were found to be most susceptible to hypnosis. Hypnosis has intrigued scientists since the nineteenth-century physician James Braid used it to alleviate pain in a variety of medical conditions, but it has never been fully understood. Hypnotized people can undergo a range of unusual experiences, including amnesia, anaesthesia and the loss of the ability to move their limbs. But some individuals are more affected by hypnosis than others — and no one knows why. Hormones and hypnotism How susceptible someone is to persuasion is an important factor in how easily they can be hypnotized by someone else. Bryant and his colleagues have previously shown that spraying a shot of oxytocin up people's noses makes them more hypnotizable, and more likely to engage in potentially embarrassing activities such as swearing or dancing at a hypnotist's suggestion. © 2013 Nature Publishing Group,
Keyword: Hormones & Behavior; Attention
Link ID: 18052 - Posted: 04.20.2013
By Luciana Gravotta If cupid had studied neuroscience, he'd know to aim his arrows at the brain rather than the heart. Recent research suggests that for love to last, it's best he dip those arrows in oxytocin. Although scientists have long known that this hormone is essential for monogamous rodents to stay true to their mates, and that it makes humans more trusting toward one another, they are now finding that it is also crucial to how we form and maintain romantic relationships. A handful of new studies show that oxytocin makes us more sympathetic, supportive and open with our feelings—all necessary for couples to celebrate not just one Valentine's Day, but many. These findings have led some researchers to investigate whether oxytocin can be used in couple therapy. The first bit of evidence that points to oxytocin as nature's love glue comes from researchers who measured the hormone in couples. Psychology professor Ruth Feldman at Bar-Ilan University in Israel, spent years studying oxytocin's role in the mother–child bond and recently decided to dive into the uncharted waters of romantic bonds by comparing oxytocin levels in new lovers and singles. "The increase in oxytocin during the period of falling in love was the highest that we ever found," she says of a study she and her colleagues published in Psychoneuroendocrinology. New lovers had double the amount Feldman usually sees in pregnant women. Oxytocin was also correlated with the longevity of a relationship. Couples with the highest levels were the ones still together six months later. They were also more attuned to each other than the low-oxytocin couples when Feldman asked them to talk about a shared positive experience. © 2013 Scientific American,
Keyword: Sexual Behavior; Hormones & Behavior
Link ID: 17796 - Posted: 02.13.2013
By Kate Clancy I tend to go to bed freezing, especially so in the winter, so I pile our flannel sheet, blanket, and down comforter over me when I settle in to sleep. A few times each menstrual cycle, clustered together in the luteal phase between ovulation and menses, I wake up from sleep completely soaked in my own sweat – not a delightful sight or experience. Usually I get up, change pajamas, and try to find a dry spot on the bed to go back to sleep (I promise the sheets eventually get washed, but I'm not about to wake my husband – and sometimes daughter – to change the bed at 3am). These night sweats started when I was still intensively breastfeeding my daughter and was marathon training, when she was under a year old. At first, I thought it was because we were co-sleeping and we slept next to each other. But I never experienced them next to my husband before that point, and he is a six foot four heat generating machine. When the marathon was over and I returned to less strenuous activity, breastfeeding frequency was also starting to decline. I didn't get any night sweats again for quite some time. Then there was roller derby. At first, roller derby was a pastime, a recreational activity where I got to learn something totally new and hang out with women I respected. But of course, being the competitive person I am, it became an obsession, and in addition to roller derby practices I was working out quite a lot on my own time. Over the last year I've made additional nutritional adjustments to further improve my performance, and I've increased the intensity of my off-skates workouts. I work out a minimum of five hours a week, but in the middle of the season it is usually a minimum of nine hours per week. © 2012 Scientific American
Keyword: Hormones & Behavior
Link ID: 17609 - Posted: 12.17.2012
By GRETCHEN REYNOLDS Is playing football like falling in love? That question, which would perhaps not occur to most of us watching hours of the bruising game this holiday season, is the focus of a provocative and growing body of new science examining the role of oxytocin in competitive sports. Oxytocin is, famously, the "love hormone," a brain peptide known to promote positive intersocial relations. It makes people like one another, especially in intimate relationships. New mothers are awash in oxytocin (which is involved in the labor process), and it is believed that the hormone promotes bonding between mother and infant. New-formed romantic couples also have augmented bloodstream levels of the peptide, many studies show. The original attraction between the lovers seems to prompt the release of oxytocin, and, in turn, its actions in the brain intensify and solidify the allure. Until recently, though, scientists had not considered whether a substance that promotes cuddliness and warm, intimate bonding might also play a role in competitive sports. But the idea makes sense, says Gert-Jan Pepping, a researcher at the Center for Human Movement Sciences at the University of Groningen in The Netherlands, and the author of a new review of oxytocin and competition. "Being part of a team involves emotions, as for instance when a team scores, and these emotions are associated with brain chemicals." Copyright 2012 The New York Times Company
Keyword: Hormones & Behavior; Emotions
Link ID: 17517 - Posted: 11.21.2012
By Scicurious Last week, Sci covered a paper on the nematode "version" of oxytocin, nematocin, and its role in learning behavior. We usually think of oxytocin-like peptides (including oxytocin and vasopressin), as being linked with emotion, trust, love, and of course, sex. But oxytocin also tends to get a lot of hype, especially as the "love"' or "trust" hormone. But it's not that. It's much more complicated than that. And understanding the evolution of oxytocin, and its very long history, allows us to understand HOW much more complicated than that. Because while nematodes have an oxytocin-like molecule that has roles in learning behavior…well it also has roles in mating. But I wouldn't go do far as to call nematocin (oxytocin + nematode = nematocin!) the nematode love drug. Unless, of course, you believe nematodes have deep, passionate, trusting, and communicative one-night worm stands which commence upon immediate contact and end immediately after. Hey, you never know. This happens to be an interesting issue of Science, in which TWO papers were published, both identifying nematocin, at the same time. As they both call the new molecule nematocin, I have hopes that the two groups were happily collaborating with each other to further the interests of science (though I know that many times, when two groups find the name new, hot thing, it's often a very bitter race to publish). So what is nematocin? Nematocin appears to be a chemical closely related to oxytocin and vasopressin, those much vaunted chemical in mammals which are making so much press for their role in our emotions and moral behavior. But oxytocin and vasopressin are both more complicated than emotion. Vasopressin, for example, plays a role in water balance. And it appears that the newly discovered nematocin in the nematode C. elegans may be similar, with more than one role in more than one system. © 2012 Scientific American
Keyword: Sexual Behavior; Hormones & Behavior
Link ID: 17512 - Posted: 11.20.2012
By Laura Beil Kotex, the company that first capitalized on the concept of "feminine hygiene" more than 90 years ago, recently gained newfound success after it began targeting an underserved market: girls who start their periods before they start middle school. With hearts, swirls and sparkles, the U brand offers maxi pads and tampons for — OMG! — girls as young as 8, promoted through a neon-hued website with chatty girl-to-girl messages and breezy videos. "When I had my first period I was prepared," reads one testimonial. "It was the summer before 4th grade…." Today it has become common for girls to enter puberty before discovering Are You There God? It's Me, Margaret. Over the second half of the 20th century, the average age for girls to begin breast development has dropped by a year or more in the industrialized world. And the age of first menstruation, generally around 12, has advanced by a matter of months. Hispanic and black girls may be experiencing an age shift much more pronounced. The idea of an entire generation maturing faster once had a strong cadre of doubters. In fact, after one of the first studies to warn of earlier puberty in American girls was published in 1997, skeptics complained in the journal Pediatrics that "many of us in the field of pediatric endocrinology believe that it is premature to conclude that the normal age of puberty is occurring earlier." Today, more than 15 years later, a majority of doctors appear to have come around to the idea. Have a conversation with a pediatric endocrinologist, and it isn't long before you hear the phrase "new normal." © Society for Science & the Public 2000 - 2012
Keyword: Development of the Brain; Hormones & Behavior
Link ID: 17503 - Posted: 11.19.2012
By Melissa Healy, Los Angeles Times If retired Army Gen. David H. Petraeus had gotten an occasional dose of supplemental oxytocin, a brain chemical known to promote trust and bonding, he might still be director of the Central Intelligence Agency, new research suggests. A study published Tuesday in the Journal of Neuroscience has uncovered a surprising new property of oxytocin, finding that when men in monogamous relationships got a sniff of the stuff, they subsequently put a little extra space between themselves and an attractive woman they'd just met. Oxytocin didn't have the same effect on single heterosexual men, who comfortably parked themselves between 21 and 24 inches from the comely female stranger. The men who declared themselves in "stable, monogamous" relationships and got a dose of the hormone chose to stand, on average, about 6 1/2 inches farther away. When researchers conducted the experiment with a placebo, they found no differences in the distance that attached and unattached men maintained from a woman they had just met. Even when an attractive woman was portrayed only in a photograph, the monogamous men who received oxytocin put a bit more distance between themselves and her likeness. But when the new acquaintance was a man, administration of oxytocin did not prompt attached men to stand farther away than single men, the researchers reported. Los Angeles Times, Copyright 2012
Keyword: Hormones & Behavior; Sexual Behavior
Link ID: 17495 - Posted: 11.17.2012
by Andy Coghlan Men with partners increase the space they feel comfortable with between themselves and an attractive woman if exposed to the bonding hormone oxytocin. René Hurlemann at the University of Bonn in Germany and colleagues gave men either a sniff of oxytocin or a placebo before asking them to choose the ideal distance for an interaction with a woman. The distance that they felt was comfortable significantly increased after sniffing oxytocin, but only for men in relationships. The team conclude that oxytocin discourages partnered but not single men from getting close to a female stranger. Journal reference: Journal of Neuroscience, DOI: 10.1523/jneurosci.2755-12.2012 © Copyright Reed Business Information Ltd.
Keyword: Hormones & Behavior; Sexual Behavior
Link ID: 17489 - Posted: 11.14.2012
by Shaoni Bhattacharya Talk about having your cake and eating it. Fasting might not be the only route to a longer life – a hormone seems to work just as well, for mice at least. We know that some animals can extend their lifespan by consuming fewer calories. Engineered mice can get the same effect by simply pumping out high levels of a hormone normally produced during a fast, according to Steven Kliewer and David Mangelsdorf at the University of Texas Southwestern Medical Center in Dallas. Their team found that mice engineered to make higher levels of the hormone, FGF21, increased their lifespan on average by over a third. "What we are seeing is the benefit of caloric restriction without having to diet," he says. Humans have the hormone too, and Kliewer believes FGF21 has the potential to extend the human "health-span" – the time we live healthy lives. The researchers believe FGF21 may act to prolong life by affecting pathways such as the insulin-like growth factor-1 (IGF-1) pathway implicated in ageing. "It blocks growth hormones promoting pathways which are associated with diseases, including cancers and metabolic diseases, and as a consequence these animals live longer," says Kliewer. © Copyright Reed Business Information Ltd.
Keyword: Obesity; Hormones & Behavior
Link ID: 17413 - Posted: 10.24.2012
Researchers in the U.S. have found signs of puberty in American boys up to two years earlier than previously reported — age nine on average for blacks, 10 for whites and Hispanics. Other studies have suggested that girls, too, are entering puberty younger. Why is this happening? Theories range from higher levels of obesity and inactivity to chemicals in food and water, all of which might interfere with normal hormone production. But those are just theories, and they remain unproven. Doctors say earlier puberty is not necessarily cause for concern. And some experts question whether the trend is even real. Boys are more likely than girls to have an underlying physical cause for early puberty.Boys are more likely than girls to have an underlying physical cause for early puberty. (Jennifer DeMonte/Associated Press) Dr. William Adelman, an adolescent medicine specialist in the Baltimore area, says the new research is the first to find early, strong physical evidence that boys are maturing earlier. But he added that the study still isn't proof and said it raises a lot of questions. Earlier research based on 20-year-old national data also suggested a trend toward early puberty in boys, but it was based on less rigorous information. The new study involved testes measurements in more than 4,000 boys. Enlargement of testes is generally the earliest sign of puberty in boys. The study was published online Saturday in Pediatrics to coincide with the American Academy of Pediatrics' national conference in New Orleans. © CBC 2012
Keyword: Development of the Brain; Hormones & Behavior
Link ID: 17401 - Posted: 10.22.2012
By Marcia Malory Ask this question, and you will probably receive one of two responses: Yes. People choose to be gay. They are making an immoral choice, which government should discourage. Or No. Sexual preference is biologically determined. Government should protect gay people from discrimination because homosexuality is an unalterable aspect of their identity. These two answers have something in common: With both of them, the science conveniently supports the moral decision. What if neither answer is right? Perhaps sexual preference can be changed – and people have the right to engage in gay sex and have homosexual relationships if they choose to do so. (The fourth option, that gay people have no choice but to be gay, but should be punished for it anyway, is morally unthinkable.) What does science tell us about sexual preference? We know, from many twin and adoption studies, that sexual preference has a genetic component. A gay man is more likely than a straight man to have a (biological) gay brother; lesbians are more likely than straight women to have gay sisters. In 1993, a study published in the journal Science showed that families with two homosexual brothers were very likely to have certain genetic markers on a region of the X chromosome known as Xq28. This led to media headlines about the possibility of the existence of a "gay gene" and discussions about the ethics of aborting a "gay" fetus. © 2012 Scientific American,
Keyword: Sexual Behavior; Genes & Behavior
Link ID: 17390 - Posted: 10.20.2012
By Tina Hesman Saey New work suggests that a hormone that makes the body think it's starving could prolong life about as long as severely cutting calories does but without the denial. A hormone called fibroblast growth factor-21, or FGF21, lengthened the lives of mice that had been genetically engineered to constantly produce large amounts of the protein, researchers at the University of Texas Southwestern Medical Center at Dallas report online October 15 in eLife. The hormone is normally made by the liver during fasting and may tap into some of the same life-extending biochemical processes as does caloric restriction, a proven longevity booster. Caloric restriction — usually defined as cutting calorie intake to 75 to 80 percent of the amount needed to maintain normal body weight, while still maintaining good nutrition — has been shown lengthen life in a wide variety of species, such as fruit flies and dogs. Minimal calorie consumption turns on many different biological processes that slow aging, says Cynthia Kenyon, a developmental biologist at the University of California, San Francisco. The hormone in the study somehow interferes with a chain reaction anchored by insulin-like growth factor-1 (IGF-1), a process that is also shut down by caloric restriction and thought to be responsible for many of its life-extending effects. In the study, researchers led by UT Southwestern's David Mangelsdorf and Steven Kliewer genetically engineered mice to constantly make five to 10 times as much FGF21 as normal. These engineered mice lived 30 to 40 percent longer than normal mice on a standard diet. Female mice benefitted from the hormone even more than males; about a third of the FGF21-producing female mice still were alive at 44 months old. Average survival for normal mice in the study was about 28 months. © Society for Science & the Public 2000 - 2012
Keyword: Obesity; Hormones & Behavior
Link ID: 17389 - Posted: 10.20.2012


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Water (Aqua), Stearyl Alcohol, Cetyl Alcohol, Stearamidopropyl Dimethylamine, Propylene Glycol, Hydroxycetyl Hydroxyethyl Dimonium Chloride, Isododecane, Fragrance (Parfum), Cyclopentasiloxane, Quaternium-91, Cetrimonium Methosulfate, Cetearyl Alcohol, Isohexadecane, Dimethiconol Quaternium-80, Glycerine, Olive Glycerides, Hydroxyethyl Behenamidopropyl Dimonium Chloride, Synthetic Wax, Polyquaternium-67, Olea Europaea (Olive) Fruit Oil, Vitis Vinifera (Grape) Fruit Extract, Panthenol, Butylene Glycol, Methoxy PEG/PPG-7/3 Aminopropyl Dimethicone, Cinnamidopropyltrimonium Chloride, Helianthus Annuus (Sunflower) Seed Extract, Benzophenone-4, Citric Acid, Disodium EDTA, Phenoxyethanol, Methylparanen, Propylparaben, Yellow 5 (CI 19140), Green 3 (CI 42053).
Best Conditioner I Have UsedI tried many different conditioners. I normally pick from the top ten picks on Folica. This was not on the top ten but thought I would give it a try. Used it with the shampoo to go with it. I have never seen my hair this shiny or hold a curl so well. It had a slip feel to it right a way when I put it in so I knew it was going to help with detangling. I used very little compared to what I normally use. I did need much with this and my hair is long and thick. Worth the price for my dry and normally not very shiny hair. I am impressed and will try the other versions of conditioners as well.
Was this review helpful?(Yes)(No)May 5, 2014LmHAIR TYPEDark Brown / Dry Hair / Curly Hair / Thick or Coarse Hair
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A Decade Of Great ConditionerHave used for a decade and love it. Keeps hair detangled and keeps ends from splitting. Not too heavy, does what it claims it will do.
Was this review helpful?(Yes)(No)Feb 26, 2014Kristen A.
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Hours & Location
Hours of operation and location of Bluford Library.
Spring Semester Hours
(Sun., Jan. 10th, 2016 through Friday, May 13th, 2016, exceptions for Spring Break and holidays)
Closed - Monday, July 4th (Independence Day)
The Bluford Library will be closed Monday, July 4th, 2016 for Independence Day. We will reopen for regular Summer Session hours on Tuesday, July 5th at 7:30am.
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YOU ARE HERE >> Careers > Career Locations > Arizona > Banner Hospice > Banner Hospice
Banner Hospice Careers
Banner Hospice have been providing comfort care for the past 10 years in the Phoenix Metro area.
The goal is to support quality of life, honor the wishes of patients, maintain the dignity of the individual and support the family through their grieving process. Inpatient Home care is also available for respite care and symptom management.
The Banner Hospice Team can provide comfort to the patient and family by alleviating symptoms, by providing meaningful help and by creating an environment to develop lasting final memories. Banner Hospice employs a dedicated team which includes nurse case managers, certified nursing assistants, medical social workers, dietitians and more.
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From 0 ratings
Dramatic foliage
Skill level
This is a recent introduction that makes a quick-growing, flashy, flamboyant show. The new spring shoots burst up through the ground, and reach full height in midsummer when they start branching and the protective, parchment-like sheaths turn white, making it one the most startling bamboos around. Gradually, the sheaths will be shed from the top downwards, though the papery sheaths at the base of the branches hang on and turn red over winter. Good for hedging, screening or as an isolated, eye-catching clump. For better winter colour, choose 'Red Sheath'.
Family: Poaceae
Genus: Fargesia
Species: robusta
Foliage colour: Mid-green
Feature: Dramatic foliage
Sun exposure: Full sun
Soil: Clay/heavy, Moist
Hardiness: Hardy
Skill level: Beginner
Height: 600cm
Spread: 150cm
Time to divide plants: March to March
Be the first reader to review the Fargesia robusta Bamboo!


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In Aurora (a.k.a. Vanishing Waves), what is the meaning of the final scene, when they are running on the beach and he finally overtakes her?
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By Kristine gill
A fleet of colorful bikes was a welcome sight Friday for paint-shop workers at General Motors Lordstown Complex who are used to working with four-wheeled vehicles.
"We gave them all custom paint jobs," joked Phil Bogunia, an alternate shop committee member.
The bikes and the mountain of neatly wrapped gifts behind them were donated — not painted — by employees and will be given to 75 children in the area through the Mahoning Valley Salvation Army. The paint shop also donated $2,100 in the form of an oversized check at a ceremony Friday.
"We have a lot of kids who are going to have an excellent Christmas," said Patricia Surratte, captain of the Youngstown Salvation Army.
It's an effort made yearly by area businesses, and GM has participated for the past eight, but last year's pile of loot was smaller.
"We didn't have as many bikes," lamented paint shop area manager Scott Negley.
Sales were down and paint shop workers were cut down to a single shift. But with Cruze sales this year, more employees were able to donate.
"It's nice to see the bikes back here," said Bob Satterlee, a zone man at the shop. "It's nice to see the big truck back."
Negley agreed. "I know for a lot of us it doesn't really feel like Christmas until we walk out here and see bicycles," he said.
Bikes were just one of the items on children's wish lists this year.
"Zhu Zhu Pets, board games, iPods, PlayStations, play kitchens, Dora the Explorer was big this year and Bob the Builder ... clothes," said Tina Law, paint shop planner.
Each year, GM workers pick out paper angels with a child's wish list, then buy and wrap the gifts.
"We try to give them everything they asked for," Law said.
Surratte was overwhelmed by the donation.
"I can't believe this," she said admiring the display. "This is beautiful."
The Mahoning Valley Salvation Army will serve 3,900 children from 900 families in the area this year. That's 600 more than last year, but case manager Tiffany Colvin said the organization receives more donations even when times are tough financially.
"The harder they're hit, the harder they come back," she said.
The mask is off. Support for the Democratic-Socialist party and/or Unions = support for the continued destruction of America.
"But, clearly, the U.S. has entered a new political moment. Heightened class and democratic struggle, the Great Recession and its aftermath, Obama's ascent to the presidency, the assertive posture of the AFL-CIO, the growth of social networks, the counter-revolt of the extreme right, all have combined to produce an unprecedented situation – and opportunity.
U.S. ideological life is also in flux. A broad radicalization process with its roots in capitalism's deep systemic crisis is at work. As polls repeatedly indicate, a broad left current flows in the streams of public consciousness: fully a third of America's youth have favorable views of socialism.
Anti-communism too is not the force it once was. Just recently in the deep south, a labor council bought an ad for the Illinois People's World annual banquet, congratulating peoplesworld.org and its labor editor, John Wojcik, for a prize-winning article, an inconceivable event in the not too distant past. In Connecticut, state AFL-CIO leaders participate in PW events where the CPUSA anniversary is celebrated; in Cleveland a well-known communist, Rick Nagin, running in a non-partisan race for City Council received the city's AFL-CIO endorsement and nearly won…
It is certainly the case that in the U.S. the real stuff of politics and governance occurs through the two mass political parties. Here is where the action is and it is here, mainly through the vehicle of the Democratic Party, that the peoples' movement fights for its interests. Serious politics cannot stand apart from these struggles…
For the foreseeable future Democratic Party circles will be an area of engagement for those wanting to make a difference."
-Joe Sims, Communist Party USA
Thank You
A worthwhile effort
For what they get paid they can afford to donate.
It's great that there are people in the community that help their neighbor during this Christmas Season.
The American spirit of giving.
What a great collaboration from GM management and the unions at the Lordstown complex to help the community. I am sure most have donated to the Valley in others ways throughout the year.
And thanks to all in the Valley who donate to all the just causes throughout the year.
@ ytowhoh330 .... Jealous? There are a lot of people in the Valley that makes the same or more than the workers at Lordstown.
GM gives Toys for Tots but not Delphi salary retirees? Boycott GM and Toys for Tots until they stop the unethical treatment of Delphi retirees OOPS... I thought I was somebody else. Great job for all the people at GM for always helping our communities.


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American Masters: Finding Lucy (2000)For more than thirty years, Lucille Ball was one of the most recognized and loved entertainers in the world. Known to all simply as Lucy, she portrayed a scatterbrained housewife with the ability to turn simple chores into unparalleled fiascoes. Clumsy and unsophisticated at nearly everything she tried (and she tried nearly everything), the television Lucy won the hearts of average Americans across all social and cultural lines with her wacky schemes. Ironically, it was Ball's wide range of experience and talents that made her such a success in this role.
To Download or Embed this video, go to this link.
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Can US Savings Bonds Be Purchased Without Refund Money?
Original post by Shula Asher Silberstein of Demand Media
For years, parents and grandparents have traditionally purchased savings bonds when children are born or when they reach important milestones so they will have money when they grow up. Savings bonds are an investment in the U.S. government as well as into children's futures. In December 2011, the U.S. government plans to stop offering these bonds for sale at banks and credit unions. However, taxpayers can still continue to purchase them using an online account or their tax refunds.
Online Purchases
As of December 2011, the U.S. Treasury plans to sell savings bonds only online through the Treasury Direct website. You can use your tax refund or a credit or debit card to purchase electronic copies of the bonds.
Paper Bonds
If you want to get a paper bond, you can still do so at banks until December 2011. Starting in 2012, a limited number of paper bonds will be printed. Taxpayers who use their tax refunds to purchase bonds will get a paper bond. All others will get an electronic bond. The bond will be stored on Treasury Direct's servers, and investors will not get a hard copy. Instead, investors can manage their bonds via their Treasury Direct accounts, including redeeming them when they mature.
Replacement of Bonds
If you misplace a paper bond that you purchased prior to the conversion to electronic bonds, you can still get a replacement paper bond after December 2011. You will have the option of getting either a new paper bond or an electronic bond. If the bond is older than its minimum redemption date, you may also redeem the bond rather than requesting a replacement bond.
The U.S. government is saving money by discontinuing the paper-bond program. In addition, converting to only electronic bonds reduces the risk of theft, loss or destruction, as there is no paper bond to steal, lose or damage. The Treasury Department will still offer paper bonds if taxpayers use their tax refunds to purchase them, so people who do not have Internet access can still purchase bonds.
- USA Today: Banks wil No Longer Sell Savings Bonds; Sandra Block; July 2011
- Treasury Direct: Treasury to End Over-The-Counter Sales of Paper U.S. Savings Bonds; July 2011
About the Author
Shula Asher Silberstein has been writing fiction and nonfiction since 2006. He writes about social issues, especially those of concern to the LGBTQ community. He has written a novel, "Shades of Gay." Silberstein holds a Master of Fine Arts in screenwriting and fiction from the University of Southern California.


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Sharing the Income
Each Community Tourism project has its own financial model but, common to all projects, all of your money will go directly to the host family, Village Society, locally-employed staff and, in some cases, a small percentage will go to the local Sarvodaya District Centre and Headquarters.
At the village level, it will be up to the Village Society to decide how their income is used to develop village facilities. At the District and HQ levels, any income will indirectly support the communities by directly supporting Sarvodaya's ongoing costs such as staffing, training, management development, transport, communication, information technology etc.


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No. 19 Men's Hoops Rallies Late For 66-62 Win Over Saint Joseph's
Jan. 8, 2014
Box Score | Notes | Photo Gallery 1 | Photo Gallery 2
An 18-to-5 run to close out the game gave the No. 19 UMass basketball team a 66-62 win over Saint Joseph's in the Atlantic 10 opener for both teams. The Minutemen trailed 57-48 with 6:23 left in the game, but clutch shooting from Chaz Williams, Maxie Esho and Trey Davis pulled UMass back for the win.
Williams led all players with 22 points while Esho scored 12 off the bench including a thunderous dunk late in the game putting UMass (13-1, 1-0 A-10) back ahead for good. Davis finished with six points, but they came on a critical three-pointer during the run and three of four free throws in the final minute of play.
Halil Kanacevic led SJU (9-5, 0-1 A-10) with 19 points and 13 rebounds. Langston Galloway scored 18 points, while DeAndre Bembry netted 16 in the loss.
Saint Joseph's led 31-28 at the intermission, but a quick 7-to-0 run put the Minutemen ahead 35-31 after a three-pointer by Raphiael Putney (11 points) just under two minutes into the second half.
The teams traded leads until an Esho lay-up tied the game at 48 each.
The Hawks began to pull away, however, using a quick 9-to-0 run over a three minute span to take a 57-48 lead with 6:23 remaining in the game.
A pair of free throws from Williams stopped the run and a steal by Derrick Gordon on the ensuing inbounds play set up a three-pointer by Davis pulling UMass back within six, 59-53 with 5:50 to go.
Williams hit a three-pointer and then one-of-three free throws in the next two minutes to pull the Minutemen within two.
The Hawks saw their lead evaporate to just one point, 62-61, before Esho forced the crowd onto their feet with a steal and a thunderous dunk putting UMass back ahead for good with 61 seconds remaining.
Saint Joseph's missed a shot on their next possession with Davis diving underneath three Hawks to secure the rebound and force a jump ball with possession going back to the Minutemen. Davis hit two free throws after being fouled on the inbounds play.
The Minutemen pressured the Hawks into another tough shot on the next SJU possession and Davis hit one of two free throws with four seconds to go. Kanacevic heaved a three-pointer from the left wing as time expired hoping to get fouled, but the shot was long.
The first half saw the Hawks jump out to a 16-7 lead after a Galloway three-pointer with 12:55 to go. In that stretch, the Minutemen were just 3-of-11 from the floor including 0-for-4 from the three-point line.
A 10-to-2 run by UMass culminated in a Williams lay-up at the 9:57 mark whittling the Hawk lead to just one, 18-17. The Minutemen tied the game just over two minutes later after a Gordon lay-up and a steal by Esho on the press turned into a dunk to even things up.
UMass led 26-23 after three free throws from Williams, but Saint Joseph's closed the half on an 8-to-2 run.
The Minutemen shot 43.6 percent for the game hitting 24-of-55 shots including 5-of-15 from beyond the arc. Saint Joseph's hit 48.9 percent of its shots on 23-of-47 shooting and was 6-of-18 from the three-point line. The Hawks outrebounded UMass 35-to-28.
The game featured seven ties and nine lead changes. UMass turned 17 SJU turnovers into 21 points and held an 18-0 edge in bench scoring.
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Year six pupils at Sandy Lane Primary School in Allerton, Bradford, organised some fun in the sun for the rest of the school to mark the end of the academic year.
The youngsters designed and created their own games for an enterprise day, which was enjoyed by parents and younger pupils at the school.
The pupils had been grilled on their designs by school governors at a Dragon's Den-style event before the enterprise day.


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- Final Fantasy XII - The Zodiac Age
Announcement Trailer
- Hard Reset Redux
Gameplay Video
- Yooka-Laylee
E3 Trailer
- Horizon Zero Dawn
Aloy\'s Journey Trailer
- Agents of Mayhem
Announcement Trailer
- LEGO Star Wars: The Force Awakens
BB-8 Gameplay Trailer
- Dangerous Golf
Launch Trailer
Dishonored Cheats
|ON OTHER PLATFORMS: PC, Playstation 3, Xbox360
publisher: Bethesda Softworks
developer: Arkane Studios
genre: Action Adventure
|ESRB rating: M
release date: Oct 09, 12
|» All About Dishonored on ActionTrip
Alive Without Breath (10): You took possession of a fish
An Unfortunate Accident (10): You killed Morgan Pendleton with steam
Art Dealer (50): You collected all the Sokolov paintings
Back Home (10): You grabbed a live grenade and threw it back, killing an attacker
Big Boy (20): You killed a tallboy using only your sword
Bodyguard (10): You protected Callista's uncle, Captain Geoff Curnow
Capturing Genius and Madness (10): You abducted Anton Sokolov, Royal Physician
Child Care (10): You located Lady Emily Kaldwin, heir to the throne
Clean Hands (100): You completed the game without killing anyone
Cleaner (10): You fought 5 enemies at once and none of them survived
Creepy Crawly (10): You used a rat tunnel
Dishonored (5): You escaped Coldridge Prison
Dunwall in Chaos (50): You completed the game in high chaos
Excommunication (5): You eliminated High Overseer Campbell
Faceless (20): After escaping Coldridge Prison, you completed a mission without alerting anyone
Food Chain (10): You assassinated an assassin
Gentleman Caller (10): You completed all the Granny Rags side missions
Ghost (30): You completed all missions after the prologue, alerting or killing no one but key targets
Harm's Way (10): You caused 5 unintentional suicides
Hornets' Nest (20): You killed 4 enemies in less than 1 second using the crossbow
Inhabitant (10): You stayed in possession of others for most of a 3 minute period
Just Dark Enough (50): You completed the game in low chaos
King of the World (10): You reached the top of Kaldwin's Bridge
Lights Out (10): You deactivated at least 5 security systems on Kingsparrow Island
Long Live the Empress (10): You saved Empress Emily Kaldwin
Manipulator (10): You made others kill 5 of their own allies
Merchant of Disorder (20): You acquired 15 equipment upgrades
Mercy is the Mark (10): You spared Daud's life
Mostly Flesh and Steel (50): You finished the game without purchasing any supernatural powers or enhancements, besides Blink
Occultist (20): You collected 10 bone charms
Poetic Justice (30): You neutralized all key targets using indirect means
Political Suicide (10): You brought about the Lord Regent's fall from grace by broadcasting his crimes
Razor Rain (10): You killed 5 characters with Drop Assassination
Regicide (10): You assassinated the Lord Regent, Hiram Burrows
Resolution (100): You completed the game
Rogue (10): You assassinated 10 unaware enemies
Shadow (30): You completed all missions after the prologue without alerting anyone
Specter (20): After escaping prison, you completed a mission, not alerting anyone and killing less than 5 people
Speed of Darkness (10): You traveled 30 meters in less than 1 second
Street Conspiracy (10): You completed all the Slackjaw side missions
Surgical (30): You played from the first mission through Kaldwin's Bridge killing fewer than 10 characters
Tempest (20): You killed 6 enemies in less than 1 second
The Art of the Steal (10): You got the Art Dealer's safe combination for Slackjaw, but robbed the safe first
The Escapist (10): After Coldridge Prison, you eluded 5 pursuers at once without killing them or leaving the map
Thief (20): You pickpocketed items worth a total of 200 coins
This Is Mine (10): You recovered your belongings
Vanished (10): You escaped prison and navigated the sewers undetected
Versatile (20): You killed characters with each weapon and offensive gadget
Wall of Sparks (10): You killed an enemy with the Wall of Light
Well Mannered (10): You completed the Boyle Estate mission without spoiling the party
Dunwall City Trials Achievements
Assassin Vs. Machine (15): Complete Train Runner before the train arrives at the station
By My Hand Alone (15): Get to Wave 13 in Back Alley Brawl killing all combatants personally
Daredevil (15): In Bonfires, perform all the special combination jumps in 1 round
Headhunter (15): Complete Assassin's Run with 100% accuracy using only head shots
Long Way Down (15): Perform a drop assassination of at least 150 meters in the Kill Cascade challenge
Mrs Pilsen's Remorse (30): Find Emily's doll hidden in each of the 10 challenges
Natural Talent (15): Finish Mystery Foe without using any active supernatural powers
Rare Collector (15): Find all of the collectable figurines in Burglar on Expert
Time Management (15): Finish Chain Kill or Bend Time Massacre without failing any wave, including bonuses
Void Star (50): Complete all Normal and Expert challenges with a 3-Stars rating
Dishonored: The Knife of Dunwall Achievements
Cleaner Hands (40): Complete The Knife of Dunwall without killing anyone
Just Business (15): You got the information you needed from the Rothwild Slaughterhouse
Message from the Empress (10): You performed a drop assassination from atop the Empress statue in The Knife of Dunwall
Missing Pieces (15): You obtained Delilah Copperspoon's identity from Thalia Timsh
No Regrets (35): Complete The Knife of Dunwall in High Chaos
Rats and Ashes (10): Attach an arc mine to a rat, resulting in a kill
Redemptive Path (35): Complete The Knife of Dunwall in Low Chaos
Stone Cold Heart (10): You spoke with the statue of Delilah in Timsh's estate
Well Connected (10): Purchase all of the Favors in The Knife of Dunwall
Whisper Ways (40): Complete The Knife of Dunwall without alerting anyone
Thief in Dishonored
Dishonored has really been influenced by the PC classic Thief: The Dark Project. To show the Devs appreciation of the game, the studio included a little easter egg. p> You can find it in Mission 7: "Flooded District" at Daud's Base. Once there, look for the two guards in training. The speech you'll hear is pretty much identical to the tutorial mission from Thief. the Dark Project.
65 or 220
|Click here for more Dishonored cheat codes
|Click here for more Dishonored cheats
|Click here to find more Dishonored cheats
|Click here for more cheat codes


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A Marine's Daughter
member for 14 years, 8 months, 22 days
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Bio and Links
I'm Becky and I'm a friend to all animals and most people. I'm an American, a Montanan, a 911 Dispatcher, an EMT, a writer, a Republican, an aviation and maritime enthusiast, a firearms enthusiast, genealogist, a pianist, an aspiring violinist, and a frustrated Raiders fan.
I have an affinity for lighthouses, airplanes and most shades of purple. I was born in Utah, reared in Montana, and consider myself a Michigander at heart. My favorite states are Montana, Michigan, and Maryland. But, I haven't been to Hawai'i yet!
I believe in God the Eternal Father and in His son, Jesus Christ, and in the Holy Ghost.
I love my country and am PROUD to be an American. I support our military. I thank our veterans and those of our allies. We owe them so much. Thank you seems so small a gesture for those who have given so much so that we could be and stay free.
I am a proud missionary aunt to Anne, who is serving in North Carolina and KayReah, serving in Colorado. I hope to follow their example someday.
There are so many people that I have a deep respect for. My parents, Walter Maurice Warner and Mildred Elnora (Nash) Warner, and my sister, Brenda Lee Warner, are among them. I suppose my favorite person ever would be my Grandma, Mary Etta (Bradley) Nash.
My ancestry includes Mi'kmaq, French, Irish, British, Scottish, French Canadian, Acadian, and others we haven't confirmed yet.
My roots run deep in Michigan, Utah, Georgia, New York, New Jersey, Virginia, Tennessee, South Carolina, Nova Scotia and Quebec.
I have been adding burials from many Southwest Montana cemeteries. I have added burials from the Montana state orphanage at Twin Bridges and the state Children's Home and Hospital in Helena. I have this listed in my virtual cemeteries.
I do this because I believe that every person/being is important and deserves to be remembered. And, if just one person finds a long-lost relative or friend from my efforts, my time has been worth it.
One of my favorite TV shows as a child was The Waltons. In a guest appearance as Martha Corinne Walton, Beulah Bondi said it best, "Neglected graves are a shameful thing." I have seen some very neglected cemeteries. But, neglected veterans' graves upset me the most. I don't believe in "non-perpetual care." I want to make something clear. When I say that neglected graves are shameful, I am talking about physical neglect-- strewn with rubbish, overgrowth, gopher holes, etc. I do not in any way mean that a grave is neglected if loved ones are unable to visit it often. Why anyone would think that is beyond me, but I've gotten enough emails that I felt the need to explain that.
For reasons I don't always understand, some people are offended to find their loved ones listed on a genealogical website. Obviously, they are not genealogists themselves. While I may not always understand their feelings, I do respect them. If a record I've added is of your loved one and you want it removed, let me know POLITELY (unlike one dolt who threatened to kill me and erroneously thought that I didn't have access to enough information about him through a single e-mail to file charges) and I will gladly remove it. I am also happy to transfer ownership to relatives. Also, feel free to use any of the headstone photos I've added for non-commercial genealogical purposes.
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Andrew Daft
Thank you!
Added by
Andrew Daft
on Jun 27, 2016 9:35 PM
Transfer of memorial
Could you transfer Dominick and Catherine Rolando to me. They are my great grandparents. 38635737 and 38635763. Thank you.
Added by
on Jun 25, 2016 12:36 AM
V Olsen
RE: Thank you
Thanks again. I am going to be a pain again. Sorry. I know how good you are about responding to edits. So I know this one got lost in the shuffle, so that's the only reason I am reminding you. It's an edit for my aunt Mary Lou Fisher 12538120 I was hoping to have it linked to my grandparent's Catherine and Iver Olsen. I put the edit in awhile ago if you are not able to find it let me know I will delete it and resubmit it so you get another notification. Thanks again. Hope the classes are going good. Sounds like fun.
Added by
V Olsen
on Jun 23, 2016 3:30 PM
RE: Carrie Garner
You are very welcome, it was my pleasure
Added by
on Jun 22, 2016 2:09 PM
Mary Lou Gilman
Bill Rollman, # 37728223
Thank you for adding his memorial to Find a Grave. Bill was my sister's son, my nephew. He died too young. I do our families genealogy and would appreciate having you transfer his memorial to me, Mary Lou Gilman #47950723.
Your profile and your body of work are truly impressive. Like you, I believe every soul has worth and deserves to be remembered. So many others on Find-a-Grave have assisted me in my search for family. I've seen your contributions for years. Thank you so much for your continued work on behalf of those living and gone.
Added by
Mary Lou Gilman
on Jun 21, 2016 9:22 AM
V Olsen
RE: Robinson
I just appreciate you doing it. I just assumed you were busy with all the other memorials you manage. Thank you so much.
Added by
V Olsen
on Jun 08, 2016 8:01 PM
Lynda Welborn Romers
William Dean Welborn #19874324
Becky, will you please correct William D Welborn Memorial? He is listed as son of James David Potts #104120027 [James David is grandfather]. William Dean Welborn is son of William Robert Welborn #104113790 and Captola M Potts Welborn #104113766. Thank you for your consideration & correction on my family member Memorials, I do very much appreciate your help.
Added by
Lynda Welborn Romers
on Jun 06, 2016 11:53 AM
V Olsen
Thank you
I just wanted to let you know how much your hard work is appreciated. It is so helpful when researching your family tree.
Thank You
Added by
V Olsen
on Jun 02, 2016 9:25 PM
V Olsen
#25846333 Joseph P. Hartmiller
Joseph Hartmiller was the son of Germany immigrants. His father, Mathew Hartmiller was born in Dirmstein, Pfalz, Bavaria. Matthew Hartmiller traveled with his family through France to board a ship to America. Joseph�s mother, Margaret Floersch was born in Worms, Rheinhessen, Hessen, Germany.
Joseph P. Hartmiller was born on June 12 ,1859 in Cleveland, Ohio and moved Montana in 1882 at age twenty-three. He worked in the Bald Butte mine in Marysville and did some placer mining on Poor Man Creek in the Lincoln district.
In 1898 he discovered a vein of silver and lead. He named the mine, the Mike Horse Mine. It is 3 miles up Beartrap Creek from the Blackfoot river. The mine was originally claimed from public land in 1890 by Joseph Hartmiller. Joseph organized the Mike Horse Mining company shortly after the discovery. By 1901 the mine adit was 1,100 ft. long. The mine was sold many times, but developers soon went broke and Joseph would foreclose and get it back.
He was married to Nellie Ellen Robinson on June 8, 1909. Nellie was born on March 20, 1886 in Lincoln, MT. Nellie's parents emigrated to America in 1870 from Stockport, England. Her parents were William Robinson and Elizabeth Davis.
Joseph and Nellie lived in Marysville. They had four daughters. Mary Josephine Hartmiller born July 16 1923 in Helena, MT. Anna Mae Hartmiller born March 30, 1920 Catherine Helen Hartmiller, who was born Sept 26, 1917. Lillie Licebeth Hartmiller, she was born July 7 1912.
Joseph P Hartmiller died of Pneumonia on January 4, 1948 in Marysville, MT. Nellie passed away the year before, March 3, 1947 in Helena.
I would like to add a bio to Joseph's Memorial and link family members.I don't know if you would rather transfer it to me or if you wouldn't mind doing it. I would be greatly appreciative either way. Thank you.
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V Olsen
on May 29, 2016 9:32 PM
Thank you!!
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Without Rhyme Or Reason
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Thunder In The Silence
Love and Loss
Quiet As A Murmur
In Our Time
Heart Attack!
Dear Diary
Nigh On Sixty!
Que Sera, Sera
Right Out Of The Blue
Cosseted In Candlelight
I Feign Consciousness
Delving Deeply Into Life
Pencilled You In
Some Words Fell.....
And By God, I Will
Recuerdame, Mi Amore.
Restless Soul
Hello, Goodbye Again....
For I Believe
If Only I ....
Heart Beats Slowly Unto Death
Love Is Leaving
Land Of The Rising Sun
Save For The Moon
My Scotland, Glencoe & Isle of Skye (video)
Happy To Be One
Writing This
Smother The Thoughts
The Politician Dogs
We Talk ......
Once I Dreamed...
Playing For Time
The Reason I Am Here
Blood Red Rose
Heather Clad Meadows
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The Celtic Spirit
The Welfare State Blues
The Artiste
Dear Love .....
Contentment, Not Love....
The Muse
Only Now.....
Peacefully, alone....
When .....
Lie In Waiting......
Love, Passionate and Free .. A Sonnet
Clock, Ticking Time... A Sonnet
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House With No Windows
Only Time...Haiku
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His Heaven A Heartbeat Away - For Thomas (Samoth)
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Here In My World
Ghosts On Glasgow Green...Ciaran Dorris
Where Willows Weep
No Tears, No Fear ....
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This Night, I Rest ......
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The Healing Heart
And So It Was ..... A Sonnet
Soft, In The Season
I Bid Thee, Heart ....
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In The Dreams, Always
To Find Him Gone...
I Remember, Recalling
Just A Letter ...Home At Last
Dead End Track
Haiku For You!
The Journey
He Sings ......
And So, I Settle....
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The Room Is Silent
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96007 Poems Read.
I Bid Thee, Heart ....
Dear Heart,
I dare not ask, if thou should love,
Seek pity from the moon above,
So oft my nights in fitful sleep,
Mine destiny within thy keep,
Wouldst thou furnish such distress?
Demand of me,
Confess, confess!
Pray tell me, Heart,
Where be thy sin?
Dost thou keep it safe within?
Be cautious, Heart,
Lest ye be weak,
Driven by such thoughts ye speak,
Banish hours; benign desire,
And dampened kindling for thy fire,
Yea, cautious Heart,
Ye seek to fly!
I bid thee, Heart,
Goodbye, goodbye.
Linda Stuart Harnett, ©2008
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Linux Foundation End User Summit Wrap-Up
We have a great sense of timing at the Linux Foundation. Who else would schedule a summit for large Linux users on Wall Street the day after "black Friday"? Actually we were worried that the news of the financial markets would distract our end users from attending the event. Luckily for us, this didn't seem to be the case. (Jim Zemlin lightened the mood with a clever presentation you should check out here.)
Companies who attended included Credit Suisse, CME, AIG, Merrill Lynch, Dreamworks, NYSE, Fidelity, UBS, NYPD, US NAVY, Metlife, Morgon Stanley, JPMorgan Chase, Aetna, NAVTEQ, Goldman Sachs, Citigroup, Mitsubishi UFJ Financial Group (MUFJ) and many more. We were pleasantly surprised to have a full house. Perhaps in these times companies are committed to making the most of their investments, especially open and lower cost investments.
Highlights of the Summit included:
A detailed unveiling of the next generation file system for Linux: BtrFS. Chris Mason of Oracle detailed how BtrFS will solve many of the issues customers are facing with all platforms as the volume of their data continues to increase. BtrFS is currently being worked on by a group of Linux Foundation members. Led by Oracle, this group also includes developers from IBM, Intel, Novell, and other companies. The group hopes to have a version in the kernel by the end of this year. Customers' initial reactions were very favorable on ease-of-use in particular. Ted Ts'o of the Linux Foundation also detailed the new ext4 file system already in the mainline kernel.
Several users are using DM multipathing in production and were very interested in the newly reworked multipathing code that is now upstream (request-based instead of bio-based) which should give better control and insight into error handling. Native device mapper (DM) multipathing was compared with commercial alternatives.
The presentation part of the file system focused more on data integrity features in the IO stack and file systems with an eye towards reducing exposure to possible data loss. Specific features that are new include the SCSI T10 DIF work (allows end to end data integrity checks), checksumming support for data and/or metadata in ext4, BtrFS and XFS, and a substantial improvement in fsck time for ext4.
The developers in attendance learned that one use-case that many large financial customers have is a large number of mid sized nodes in a data center (say 2000 or so) which have relatively little data on local hard disks and rely on network file systems (NFS or AFS today) to supply the critical data. There was interest in the still in-development work on parallel NFS (part of NFS v4.1 and heavily promoted by large storage vendors like EMC and NetApp) and some interest in persistent NFS client caching (again, actively under development, not in upstream).
Community representatives encouraged these large consumers of Linux to advocate for open source drivers from their suppliers so that they can be properly supported.
Also, they were offered help evaluating upstream (non-distro) kernels to give them a chance to validate and suggest fixes or tweaks on the very newest technology. One large bank agreed to begin testing these newer, non-distro kernels and give feedback to the community. On the competitive side, no users were found that had actually deployed ZFS in a production environment.
In the best example of the intention and promise of the event, end users, developers, and vendors met for multiple hours on the topic of systems management in Linux. System management leaders received valuable operational requirements for performance monitoring from customers. As a result of these meetings, the end user council of the Linux Foundation will now create use-cases and other detail that will then be given to community developers and vendors. This type of collaboration is invaluable in advancing the state of the art of the Linux platform. The Linux Foundation will report on results from this collaboration next year.
In other systems and performance management sessions, it was found that users in attendance had experiences and best practices but not always the awareness of the wide variety of tool/community choices. As a result of this meeting, a blueprint or web based knowledge center will be created on the Linux Foundation site. Both the vendor and user advisory councils will contribute to this knowledge center and encourage its use by a wide audience.
Gerrit Huizenga from IBM gave a well received session on Cloud Computing and how Linux is the OS of the cloud. The Linux Foundation will be publishing a paper on cloud computing in the next month.
I want to thank all of our speakers. We had amazing community developer and vendor participation from the likes of IBM, Oracle, Intel, HP, Fujitsu, Novell, Red Hat and many more. You can find slides from many of the sessions here. I actually thought there would be more arguments getting these groups together. I was pleasantly surprised at how everyone worked well together. While there are some things I will change for next year (especially the length of day one) I think overall it was a successful and useful event. I want to thank our members for supporting this effort at enhancing collaboration in the Linux platform.


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Send us your memories of Asbury Park
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Here to Send Us Your Story and Memories of Asbury Park
remember Asbury
Park in its period of decline from about 1984-1988.
Every summer my family would visit my grandparents who had a
house on Shark River. And my sister and I would literally beg
my parents to take us over to Asbury
Park to go on the Ferris Wheel or to the carousel or
the other miscellaneous rides. My Personal favorite memory is
my first trip through the Asbury Park Circus Fun House. That
was probably round 1988 or 87, my last trip there. I remember
my dad commenting how this place would be gone within the next
few years and how we would never come back, sure enough he was
right it was gone in the next 3 years. 2 Years ago, my friends
and I visited the aging Asbury Boardwalk, and I was distressed
at the conditions of the once majestic boardwalk. My friends
had never been to Asbury while it was still opened up so I
pointed out all the former highlights. When I look at the
photos of the desolate boardwalk now I try not to focus on the
bad points but rather I see an area still loaded with promise.
I can see a bustling boardwalk, rides and amusements to rival
seaside. I can see people from all races, creeds, and walks of
life bringing their children there to experience the fun and
beauty of this historic place on the Coast
family vacationed in Ocean Grove from at least 1955 when I
was born until I was 16 or 17 years old. Every night
after a long day on the South End beach we would walk up to
Asbury to go on the rides and walk through the shops.
There are so many things I remember! The gold ring on
the merry-go-round in the Palace, the grouchy old man who
ran the push arm machines in the Palace. They were
enclosed in glass so you could see the prizes spinning round
and round. We would put our fingerprints all over the
glass just to rile him up. Also in the Palace was the
Tilt-a-Whirl, The Funhouse, the Rock-o-Plane, the big Ferris
wheel and of course Ski Ball. In later years the put
up the self propelled cage ride by the lake where the little
motor boats were. After the Palace we would go back
out on the Boardwalk and go up as far as Convention Hall.
Once past Convention Hall there was only one or two more
shops and then deserted Boardwalk. We would head back
home, maybe grab a piece of taffy or a Waffle and Ice Cream.
Just before you got back to OG there was a little nook where
you could buy what seemed like any flavor soda in the world
for a nickel. It was set up like an automat with each
flavor behind its own door. Remember the guy who drew
portraits in a little building in front of the North End
Hotel? (Zad or Zack?) I remember the Casino
being on fire and watching it burn from the beach.
I�d love to hear from any one with more memories. Thanks,
I remember Asbury when it was
alive. I owned the Kingsley Arms Hotel for two years and lived
in Asbury for that time. It was the an amazing two years.
Bruce Springsteen
Asbury Park's Glory Days:
The Story
Of An
American Resort
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text:
ELYRIA – Defense told the story of Elyria Catholic`s 6-1 Division III sectional victory Thursday over Oberlin.
Elyria Catholic (11-5) had it, Oberlin (9-9) didn`t.
None of the Panthers` six runs was earned, helped by a whopping five errors, along with four wild pitches and a passed ball.
Elyria Catholic had no errors plus a fantastic defensive play by Jasmin Filiaggi. The left fielder chased down a low line drive by Nicole Isabell, making a diving, shoestring grab after a long run in the sixth.
"I looked out there and said, 'Oh, my God, she caught it,`" said Lauren Whited, who played a big role as the winning pitcher. "I don`t think I`ve seen a better play, ever. She is so good!
"Overall, we had great defense today."
Whited had a perfect game through four innings when Amari Foster sent a shot to left. But Foster was picked off rounding first by a perfect relay.
Oberlin finally scored in the seventh when Whited gave up a double to Foster and a single to Jessica Dakos.
"I wasn`t getting tired," Whited said. "My pitches suddenly weren`t working as well."
But for most of the game she was very sharp, using her change-up often as she struck out eight and didn`t walk a batter.
Elyria Catholic scored first in the third when Filiaggi beat out a bunt for a hit, was sacrificed to second, went to third on a wild pitch and scored on a throwing error by the catcher. The Panthers made it 2-0 in the fourth on Emily Taylor`s single, a passed ball, stolen base and an error by the third baseman.
The Panthers put it away with four in the sixth as Oberlin committed two more errors.
Elyria Catholic will play at Hillsdale this afternoon in a sectional final.
"They booted the ball," Elyria Catholic coach Brian Daw said. "But that was from us putting runners on base, causing pressure on their defense.
"Lauren was really on her game today. Her change-up was great. "
Of Filiaggi`s catch, Daw added: "That was a fantastic catch. In my 20 years of coaching I`ve never seen a player with that speed."
"Big players step up in big games," said Oberlin coach Rick Twining. "Our players just didn`t step up today. This was by far our worst defensive game of the year. But we only have two seniors, so maybe the players coming back can grow from this."
Contact Jerry Rombach at 329-7135 or firstname.lastname@example.com.
Sectional softball: Elyria Catholic does it with defense
ELYRIA – Defense told the story of Elyria Catholic`s 6-1 Division III sectional victory Thursday over Oberlin.


text:
IMF Executive Board Concludes 2012 Article IV Consultation with RomaniaPublic Information Notice (PIN) No. 12/122
October 23, 2012
Public Information Notices (PINs) form part of the IMF's efforts to promote transparency of the IMF's views and analysis of economic developments and policies. With the consent of the country (or countries) concerned, PINs are issued after Executive Board discussions of Article IV consultations with member countries, of its surveillance of developments at the regional level, of post-program monitoring, and of ex post assessments of member countries with longer-term program engagements. PINs are also issued after Executive Board discussions of general policy matters, unless otherwise decided by the Executive Board in a particular case. The staff report (use the free Adobe Acrobat Reader to view this pdf file) for the 2012 Article IV Consultation with Romania is also available.
On September 28, 2012, the Executive Board of the International Monetary Fund (IMF) concluded the 2012 Article IV Consultation with Romania.1
Following the severe downturn in 2008–09, the Romanian economy has undertaken a large adjustment to restore macroeconomic stability. Under two successive IMF Stand-By Arrangements and with support of the European Commission and the World Bank, significant progress has been made in reversing large external and internal imbalances. Sustained fiscal consolidation, mainly achieved through spending constraints of the wage bill and public pensions, has resulted in a significant reduction of the fiscal deficit. Growth resumed in 2011 and annual inflation has declined to record lows earlier this year. Unemployment remains high, but labor market reforms have contributed to a better-functioning labor market and a recovery in employment. Bank capital buffers have been shored up and contingency plans have been prepared. Structural reforms in the energy and transportation sectors have progressed, albeit slowly. These policy actions have helped to ease financing pressures and allowed Romania renewed access to the Eurobond market.
Nevertheless, the post-crisis recovery remains fragile and the outlook is challenging. With strong trade and financial sector linkages to the euro area, Romania remains vulnerable to the regional economic slowdown. While the economy is expected to grow by 0.9 percent this year, the growth momentum has been weak, and is lagging behind most other European emerging economies. Difficulties in absorbing European Union structural funds and frequent delays in advancing the structural reform agenda are weighing on the economy's potential growth. The weak recovery together with the so far moderate ongoing private sector deleveraging, mainly concerning households, are impacting the banking system as nonperforming loans accumulate, bank profitability continues to be low, and real credit growth remains subdued. Heightened uncertainty owing to political tensions between the ruling coalition and the President has taken a toll on investor confidence, leading to capital outflows and exchange rate depreciation pressures. These developments along with rising inflationary pressures have underscored the need for a prudent monetary policy stance. Strong commitment to achieving fiscal sustainability and judicious implementation of the structural reform agenda remain crucial to anchor policy credibility, ensure macroeconomic stability, and boost inclusive growth.
Executive Board Assessment
Executive Directors commended the Romanian authorities for restoring macroeconomic stability and reducing large external and fiscal imbalances. Directors noted however that the difficult external environment and domestic political uncertainty are weighing on the economy. They welcomed the authorities' continued commitment to the program objectives, stressing the importance of sustained policy discipline and accelerated implementation of structural reforms to reinforce the economy's resilience and boost its growth potential.
Directors commended the sizeable fiscal adjustment undertaken and welcomed the authorities' commitment to stay within the 2012 fiscal target of 3 percent and reach the medium-term objective by 2014. They recognized the significant progress made in reducing current spending and encouraged continued restraint ahead of the upcoming elections. Directors emphasized the importance of prioritizing capital outlays and improving EU funds absorption. They also underscored the need to take remedial measures to reduce outstanding arrears and avoid further accumulation of arrears, in particular at the local government level. Reform of the healthcare system should help address medium-term fiscal pressures, while improving service delivery.
Directors stressed that accelerating the pace of structural reforms is critical to fostering higher and inclusive growth. They welcomed the progress on labor market reform and energy prices but underscored the need for further action in the energy and transportation sectors, while protecting the poor. Deeper reform and privatization of the state-owned enterprises and improvements in the institutional and regulatory frameworks and the business climate are priorities going forward. Directors also called for stepped up efforts to increase the employment rate and reform the education system.
Directors underscored the importance of pursuing a prudent monetary policy stance while maintaining exchange rate flexibility. They encouraged the central bank to limit intervention in the foreign exchange market to smoothing volatility and to stand ready to tighten the policy stance should exchange rate pressures persist. Directors noted that the Romanian banking system maintains significant buffers to deal with the potential adverse effects of tensions in euro area financial markets. They encouraged the authorities to continue to strengthen bank supervision and the financial sector safety net, and mitigate the rise in nonperforming loans.


text:
I use the standard notations. When $x$ is real then by definition $$ I_{\nu}(x)=e^{-\nu\pi i/2}J_{\nu}(ix). $$ I want to define $I_{\nu}$ for complex $z$. Watson (Treatise of the Theory of Bessel Functions, 2nd ed, 3.7, p.77) says it is $$ \begin{cases} I_{\nu}(z)=e^{-\nu\pi i/2}J_{\nu}\left(ze^{\pi i/2}\right), & (-\pi<\arg z\leq\pi/2),\\ I_{\nu}(z)=e^{(3/2)\nu\pi i}J_{\nu}\left(ze^{-(3/2)\pi i}\right), & (\pi/2<\arg z\leq\pi). \end{cases} $$
Q1. $e^{\pi i/2}\neq e^{-(3/2)\pi i}$?
Q2. Why not good to simply put $z$ in place of $x$?
Q3. How was chosen these two cases of argument of $z$? What is the reason?
Watson says "it is usually convenient", but I want mathematical justification.


text: I've written an entirely custom vncserver script that we use internally. One of the customizations we have allows for "global" settings for things like the geometry and color depth and those settings can be overridden by user customizations by looking at parameters inside a ~/.vnc/Xvnc.rc file. - Jeff On Mon, 2004-04-05 at 13:19, William Hooper wrote: > Robert Swan said: > > Does anyone know how to specify the server geometry in a configuration > > file, rather than on the command line? > > Assuming you are referring to a *nix OS, you can edit vncserver (it is a > perl script) and change the default.