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Jan. 18, 2013
TULSA, Okla. -- Almost four hours after play began, Max Manthou capped a Washington comeback as the Dawgs defeated Tulsa on its home court, 4-3. After being dominated in doubles, the Dawgs fought hard in singles, scraping out a huge early-season win over a top opponent.
Manthou played an epic match against Grant Ive, winning 11-9 in a third-set tiebreak to earn the win for Washington. Manthou took care of business in the first set, winning 6-2, but dropped the second set, 6-3. In set three, Manthou and Ive traded rallies, taking the final set into a tiebreak until Manthou finally won the decisive point with his teammates cheering him on.
Also winning singles matches were Kyle McMorrow, Viktor Farkas and Jeff Hawke. McMorrow won No. 79 of his career to move into a tie for eighth all-time at Washington. He defeated No. 34 Japie De Klerk of Tulsa, 7-6, 6-0.
Farkas, playing at No. 3 singles also disposed of a ranked opponent, defeating No. 68 Alejandro Espejo, 6-2, 6-2. Finally, Jeff Hawke defeated Tristan Jackson, 6-2, 3-6, 6-1, playing at No. 6 singles.
Tulsa earned its points in singles by wins at No.2 and No. 5. Clifford Marsland defeated Emmett Egger, 6-2, 6-2, while Carlos Bautista beat Nicholas Kamisar, 6-3, 7-5.
The Dawgs began by dropping the doubles point to Tulsa as the Golden Hurricane's top two teams defeated their UW counterparts. Marsland and Espejo defeated Marton Bots and McMorrow, 8-3, followed by Ive and Jackson beating Egger and Manthou, 8-3.
In the final doubles match de Klerk and Bautista beat Jeff Hawke and Viktor Farkas, 8-3.
Washington will be back at it tomorrow when it faces No. 23 Texas back at the Case Tennis Center. The Dawgs hope to finish a 2-0 weekend against another tough opponent. First serve is set for noon Pacific Time on Saturday.
Washington Men's Tennis
Case Tennis Center - Tulsa, Okla.
January 18, 2013
No. 25 Washington 4, No. 17 Tulsa 3
1. Clifford Marsland/Alejandro Espejo def. Marton Bots/Kyle McMorrow, 8-3
2. Grant Ive/Tristan Jackson def. Emmett Egger/Max Manthou, 8-3
3. Japie De Klerk/Carlos Bautista led Jeff Hawke/Viktor Farkas, 6-3
1. Kyle McMorrow d. No. 34 Japie De Klerk, 7-6, 6-0.
2. Clifford Marsland vs. Emmett Egger, 6-2, 6-2.
3. Viktor Farkas d. No. 68 Alejandro Espejo, 7-5, 6-3.
4. Max Manthou d. Grant Ive, 6-2, 6-3, 7-6 (11-9).
5. Carlos Bautista vs. Nicholas Kamisar, 6-3, 7-5/.
6. Jeff Hawke d. Tristan Jackson, 6-2, 3-6, 6-1.


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UA Mascot Tryouts 2013
Do you have what it takes? If you think you have the skills, passion and swag to be the next Wilbur or Wilma here is your chance!
Wilma Wildcat can't think of any better or more appropiate hands-on (paws-on)way to show her pride and spirit for the university. Wilma loves interacting with the children. "They gaze up into my eyes, tell me they love me, and that im their best friend". She describes it as "a very rewarding feeling to be there for these children". Wilma's most memorable experience was having 2 little boys come up to her, asking her to marry them. According to Wilma, she never encountered anything cuter in her entire life. A lision between the UA community and Tucson, Wilma Wildcat supports various community events. At games, she helps keep crowds and fans motivated with her enthusiasim and strong UA spirit. She attributes her success as a kind, loveable wildcat to the endurence, preperation, and devotion she possesses.

subset: commoncrawl


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Police Report: Jan. 29, 2014
Published: Wednesday, January 29, 2014 at 10:00 p.m.
Last Modified: Wednesday, January 29, 2014 at 10:00 p.m.
Portions of the following information are based on facts provided by the arrested individuals. Those individuals have been booked with, not convicted of, the offenses shown. All accused should be presumed innocent until proven guilty.
Jan. 29, 2014
Lafourche Sheriff's Office
Raven Guidry, 23, 108 St. Peter St., Thibodaux, possession of methamphetamine, possession of marijuana, illegal use of a controlled dangerous substance in the presence of a juvenile.
Carl Miller, 44, 134 Dupre St., Houma, contempt of court.
Alvin Goff, 40, 2544 Lionel Washington, Lutcher, two counts of contempt of court.
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.


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I have to say one of my best investments is going with all recyclable bottles. It's finally summer here in the pacific northwest and that means I'm really starting to carry around extra bottles. I was able to check out Kirkland's products. I personally love the animal print tumbler. They are BPA free and have… [read more]
Archives for June 2011
Monte Carlo: The Must See Summer Movie!
This is a Sponsored post written by me on behalf of Monte Carlo for SocialSpark. All opinions are 100% mine. Moms grab your girls and see the summers hottest movie Monte Carlo. Now as my daughter is a huge Selena Gomez fan I can say she'd enjoy this movie that's truly meant for girls. The… [read more]
Kolcraft's 65th Anniversary – Win Big In The Sweepstakes
Kolcraft has been a part of Brooklin's life since she was born. Looking back Kolcraft has probably been in your child's life at some point. From brands like Jeep, Contours, Sealy, and Sesame Street. Kolcraft is celebrating 65 years of serving families. Kolcraft is so excited because they are the only baby gear & crib… [read more]
My View – How Mom Blogging Came To Be
Back In The Day. I had a conversation with a mom blogging veteran a few weeks ago and we got on to talking about "the old days" where we were learning and teaching small and big brands along with our fellow bloggers how to do this whole blogging business thing especially the "mommy blogging" thing. … [read more]
Portland Family Fun – Portland Fourth of July Festivities & Fireworks
The weather is set, we're going to have a gorgeous Portland fourth of July weekend. If you live within the Portland metro area maybe you're looking for activities. Here's a list of things to do within the Portland metro area this weekend.Our family will be at a fort just across the river, celebrating with a… [read more]
Fun Foods For The 4th – Spice Up Your Burgers With Mini Chicken Burgers
Nothing says BBQÂ without burgers, I'm sure chicken burgers aren't sounding too great right about now but it's such a fun little burger I wanted to inspire you all right before 4th of July. Lets face it, chicken isn't exactly cheap compared to mass produced ground beef. I found these adorable mini burger buns at… [read more]
Are All Foods Created Equal? Why You May Want To Reconsider Organic Foods.
If you keep up with Our Ordinary Life, you know that we are avid supporters of products and foods that are organically grown. Here is a summary of what constitutes organically grown foods. Some people think it is a marketing ploy but the fact simply is that it's far from a ploy. The way something… [read more]
Photography – The Halo Around The Sun on June 26, 2011 – Do you have any Pictures?
Does anyone know what's going on? This is what the sun looks like from outside my house in Beaverton, Oregon. It's hard to look at but you can see the halo around it clear as day. Someone else has to have noticed it too. I have no idea what is going on but while at… [read more]
Portland Family Fun – U Pick Farms Portland and Orchards Near The Metro Area
There's nothing quite like picking your own fresh fruits, berry's and fresh locally grown vegetables. There are so many farms around the Portland metro area and all of them are worth visiting at some point in the year. U Pick Farms Portland and Orchards Near The Portland Metro Area Baggenstos Farm Store – strawberries, raspberries,… [read more]
All-Wheel Drive & A Sandy Beach With A Chevy Girl In Her 2010 Equinox LTZ
The Chevy Equinox is a great vehicle for getting around the city, to driving though Pacific Northwest hills and mountains, to taking scenic drives that require time and a comfortable ride. The Equinox LTZ came equipped with an all-wheel drive (AWD) system and a powerful V6 that has torque making it nimble for its size.… [read more]


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Lawrence D. Pete
Position: NT-DT
Height: 6-0 Weight: 286 lbs.
Born: January 18, 1966 in Wichita, KS
High School: South
College: Nebraska (school history)
Drafted by the Detroit Lions in the 5th round (115th overall) of the 1989 NFL Draft.
Weighted Career AV (100-95-...): 11 (6880th overall since 1950)
Let people know you like this site. Sponsor this page for $5. Your message will replace this ad.
Output includes all games from 1920 to 2015.


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There's a new $.25 Off Vanity Fair Napkins Coupon available, while prints last. Hang onto it for this upcoming deal at Walgreens starting the week of 10/19/14:
Vanity Fair Napkins BOGO @ $2.99
*Use $.25 Off Vanity Fair Napkins Coupon
Earn 2,000 Rewards Points wyb 2
FINAL PRICE = Like getting them for 2/$.74 after coupon and points.
Note: Your initial out-of-pocket expense will be $2.74 plus tax for 2 packs.
Thanks, Couponing For 4!
Plan Ahead: You can pick these up for Thanksgiving or holiday parties!
Remember, this deal doesn't start until 10/19/14 but you may want to grab the coupon now as it could be gone by then!


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By Daniel Severn
This week's exercise is designed to help build better aerobic and anaerobic endurance. It involves short sprints, quick changes of direction, recovery defending and also helps to develop a better focus and awareness. The exercise is played at a very high tempo with the players rotating each time the ball goes dead (goal, turnover in possession, ball out of bounds).
Set Up and Directions
For this exercise you will need 4 goals, a set of soccer balls and a minimum of 8 players divided into 2 teams. Mark out a 20×20 meter area. Set up is shown below (Fig 1).
Ensure each team has a good supply of soccer balls; this will help to keep the rotation fast and intensity high. One point is scored for each goal; with the winning team being offered a reward (providing motivation is very important for good intensity and work rate during practice). For this particular exercise, I will often carry the score over to the scrimmage – providing players with a chance to start the scrimmage with a lead.
Play begins when one of the attacking players dribbles the ball onto the field, the defenders may enter the field as soon as the attacker does so. The attackers must try to score in either goal on the opposite side of the field to which they start. The defenders must try to stop them from scoring by winning the ball from them.
Below we see the attacking player making a pass to his open team mate and a shot on goal (Fig 2.)
The play is over when:
- The attacking team scores
- The ball goes out of bounds
- The defending team steals the ball
As soon as the ball goes dead, the players that were defending move off the field as quickly as possible, the attacking players become the new defending players and the players resting on the original defenders side of the field, become the new attackers – as shown below (Fig 3).
This rotation is continuous. I often put a time limit on the game in order to keep the intensity and work rate. I recommend 3 minute games with 1 minute rest.
A key factor of this exercise is the transition from attack to defense. The players must be alert to this switch from the instant their attack ends. Encourage the pair waiting to attack, that they should start very fast in order to try and catch the defenders out.
Progression – Counter Attacking
Now, when the pair that starts as the defenders steals the ball, instead of the play being over, they now have a chance to counter-attack and score themselves. This allows for a more game-like, continuous play, as opposed to short, fast attacks.
The transition remains the same, with the attacking team becoming the defenders, the defenders rest and a new pair will come in to attack. Just remember who started the play, as now either team can score!
Two or Four goals?
I use four goals for this exercise as this requires the players to develop their awareness. With two goals to defend and two to attack, you have much more to think about whatever your role on the field.
As defenders, if you do not understand your surroundings (i.e. exactly where the goal is that you're defending, where the player is that is running off the ball) then you may make the attackers' job easier. As attackers, it is important to have a good awareness of your surroundings in order to give yourself the best chance to shoot and to take advantage of any poor defensive positioning.
Using two goals is just as fast paced and still very exciting.
Dan Severn, Program and Events Manager – BRASA Brazilian Soccer Academy


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Way Back Showtimes and Tickets
Read Movie Reviews about Way Back Write a Movie Review for Way Back
Release Date: 2011-01-21
Genre: Drama,
Rating: PG-13
Duration: 2hrs 12min
The Way Back begins in Soviet-occupied Poland, as a military officer named Janusz (the film's stand-in for Rawicz, played by the young English actor Jim Sturgess) is interrogated and then sent to Siberia after his wife is tortured into incriminating him. One of the year's most powerful scenes, this stunner of an opening telegraphs the film's merciless, unflinching approach. There's no physical violence on the screen, but Weir punches us in the gut simply by training his camera on Janusz's face as his eyes fill with fear, which turns to horror and then anger. The gulag is torture. Desperately malnourished men fall trees in the brutal cold or slave in poisonous gold mines. The guards inform them that it is not fences, guards, guns or dogs that make up their prison, but the murderous snow-swept isolation of Siberia. Inspired by a fellow political prisoner (Mark Strong) who latter turns out to be all talk, Janusz quickly hatches a plot to cut the electrical wire and, during a snowstorm that will cover their tracks, hoof it thousands of kilometers south to Lake Baikal. A few prisoners who have retained the will to live – including an American expatriot (Ed Harris), a Russian hoodlem with Stalin's face tattooed on his chest (Colin Farrell), a priest (Gustaf Skarsgard), an artist (Alexandru Potocean), and a teenage boy (Sebastian Urzendowsky) come along. Only three men of the med ultimately make it to India.
Cast and Crew
- Starring
Ed Harris, Colin Farrell, Jim Sturgess, Mark Strong, Saoirse Ronan
- Directed by Peter Weir
- Written by Peter Weir, Slavomir Rawicz
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By Tom Morphet
October 3, 2013 | XLIII 39
Carry a bright flashlight and don't talk to an angry moose.
That's the advice of 40-year-resident Deb Marshall after being stomped Sept. 19 near the Paradise Cove beachfront home of George Figdor.
Marshall was walking about 150 yards to Figd...
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Allergy & Immunology Fellowship Training
Work Rounds:
Tuesdays noon R304
A forum for challenging clinical problems and enigmas
Chest Conference/Pulmonary Allergy and Critical Care Grand Rounds:
Wednesdays 4 PM
The entire pulmonary, allergy and critical care division along with several community-based practicing physicians attends the weekly Grand Rounds. At this interactive conference, first year fellows present clinical cases to faculty members. Key elements of the case are discussed. At the end of the discussion, first year fellows present a summary of the relevant literature. The intent is to highlight new and classical literature regarding diagnosis, treatment, or disease mechanisms. During the year, a broad variety of cases is presented, including: usual and unusual sinus and pulmonary infections; usual and unusual issues in asthma diagnosis and management; drug-induced pulmonary disease and other drug allergies; nasal, laryngeal and chest cancer; acute lung injury; interstitial lung disease and vasculitis. In addition, several conferences are devoted to core topics in allergy/immunology, sleep, and exercise physiology.
Journal Club:
Wednesdays 5 PM
Once a month, a journal club follows the case based conference. A fellow and faculty member presents a selected article and oversees the ensuing discussion. The goals are to identify new and interesting clinical findings, and to teach a critical reading of the literature in pulmonary, allergy and critical care medicine.
Senior Fellows' Allergy/Pulmonary Conference:
Thursdays 12-1 PM
This is a weekly conference that is run by senior fellows. Individual senior fellows lead a case-based discussion on a specific topic along with a review of the pertinent literature. The conference varies from reviewing interesting radiography, case management issues, global trends in allergy and pulmonary care, and new treatment strategies. A/I fellows and faculty routinely present overviews of key issues in A/I management in addition to interesting patient-oriented issues.
Pulmonary Immunology Conference:
Thursdays 9-10:00 AM
Lab research conference and journal club
Work in Progress:
Fridays 8:30-9:30 AM
Presentations by faculty and fellows of ongoing research and by Visiting Professors from outside institutions.
Boston City Wide Allergy Immunology and Respiratory Conference:
Second Tuesday of the month
Allergy & Immunology Core Curriculum Outline and Training Program Directors' Reading List
The AAAAI Training Program Directors' (TPD) Core Curriculum Outline is updated every three years by the Core Curriculum Subcommittee of the TPD and is consistent with the requirements of the ACGME Residency Review Committee for training in allergy and immunology. The TPD Core Curriculum outline serves as a guide for our program's curriculum.
The TPD Reading List includes articles that are felt to be the best resources for the topics covered in the Training Program Directors' Core Curriculum. This can be accessed through the AAAAI.org web site for fellows or by clicking here. Fellows will need to fill out an online form to obtain a password.


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I Fall in Love Too Easily
Miles Davis Quintet
Absolutely freeEvery time we post a new video,we'll send you a notice by e-mail.
Davis: May 26, 1926 – September 28, 1991
The Miles Davis Quintet perform "I Fall in Love Too Easily" during a 1967 concert.
The song was composed in 1944 by Jule Styne, with lyrics by Sammy Cahn, and introduced by Frank Sinatra in the 1945 MGM film "Anchors Aweigh." It has since been adopted as a popular jazz standard.
Miles Davis, trumpet
Wayne Shorter, sax
Herbie Hancock, piano
Ron Carter, bass
Tony Williams Karlsruhe, drums
That's how we grow.
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During the May 1 episode of the Dr. Oz Show, Dr Oz along with Pediatrician Alan Greene shared the effects microwave popcorn has on the body. Popcorn itself is a very healthy smack but can be toxic when coupled with the chemicals carried into the body through the popcorn is what makes this popular treat a hazard to the human body.
PFOA carcinogen
Microwave popcorn bags are generally lined with perfluorooctanoate acid (PFOA). PFOA is formed as a byproduct in the production of fluorotelomers. Fluorotelomer coatings are also used in fast food wrappers, candy wrappers, and pizza box liners.
PFOA is used to line the bags to provide a lipophobic effect which prevents the oil from soaking through the bag. An estimated 20% of PFOA can be found in the human body at any time and is a direct result of microwave popcorn.
PFOA is a known carcinogen yet is still approved by the Food and Drug Administration at designated levels. PFOA can inflame the bladder causing the bladder to bleed and may lead to bladder cancer. Also, the effects of PFOA can lead to thyroid disease and respiratory problems.
Diacetyl causing "popcorn lung"
Another highly toxic chemical used in the production of microwave popcorn is diacetyl. Diacetyl is one of two compounds that provide a butter-like flavor to popcorn and other packed foods. Ingesting diacetyl regularly over time can cause lung disease.
People working in factories where microwave popcorn is manufactured may develop what is known as "popcorn lung" due to the exposure of diacetyl. "Popcorn lung" is also known as bronchiolitis obliterans in which the air ways in the lungs become scarred and obstructs breathing.
Trans Fats
The presence of trans fats in food has become a growing problem among the public in recent years. Obesity and diseases directly related to diet has have been linked to unhealthy fats. Trans fats are widely used in packaged foods due to the long shelf life of this fat.
Dr. Oz recommends preparing air-popped popcorn on the stove top or purchasing organic packaged popcorn that clearly states the omission of harsh chemicals.


text: Human Services Sample Schedule/Paradigm A guide for completing your Human Services major+ More The paradigm below is one example of how this major may be completed. Students may use their elective credits to explore other majors or to enroll in skill-building courses in mathematics, reading, writing and/or study skills. With planning, students may use these credits to complete a minor, enroll in a practicum or internship, or study abroad. Freshman Year - Fall LCT140 First Year Seminar 3 E120 English Composition 3 HS111 Introduction to Human Services (Area HS) 3 PY111 General Psychology (Area HS) 3 TA101 Oral Communication 3 Credits: 15 Freshman Year - Spring HS211 Interviewing & Assessment 3 B200/B201 Human Biology & Lab (Area NS) 3 ST132 Reasoning with Statistics (Area QS) 3 General Education Content Area 3 General Education Content Area 3 Credits: 15 Sophomore Year - Fall LCT225 Perspectives (may be taken spring semester) 3 ID160 Artscore 2 HS298 Field Exploration 2 PY211 Developmental Psychology 3 General Education Content Area 3 General Education Content Area 3 Credits: 16 Sophomore Year - Spring HS306 Case Management 3 S250 OR Logic of Analysis 4-3 PY290 Experimental Psychology & Statistics HS298 Field Exploration 2 General Education Content Area 3 General Education Content Area 3 Credits: 16-15 Junior Year - Fall LCT375 Global Issues (may be taken spring semester) 3 S350 Field Methods 4 Human Services Elective - Upper-division 3 Human Services Elective - Upper-division 3 General Education Content Area 3 Credits: 16 Junior Year - Spring HS495 Internship Planning (summer or fall internship) 1 Human Services Elective - Upper-division 3 Human Services Elective - Upper-division 3 General Education Content Area 3 Elective 3 Elective 3 Credits: 16 Senior Year - Fall Study Abroad OR Semester abroad in an approved program 16 HS496 Human Services Internship 6-15 HS498 Internship Integration 2 HS495 Internship Planning (needed previous Spring Semester) OR LCT475 Capstone 3 Elective 3 Elective 3 Elective 3 Elective 3 AND EITHER HS489 Thesis Development 3 OR HS495 Internship Planning (Spring Internship) 3 Credits: 15-17 Senior Year - Spring LCT475 AND EITHER Capstone (if not satisfied fall semester) 3 HS496 Human Services Internship and 6-15 HS498 Internship Integration 2 HS495 Needed previous Fall Semester OR HS490 Research in HS (HS489 needed Fall) 2 Elective 3 Elective 3 Elective 3 Elective 3 Credits: 15-17 The following is recommended: Minimum 400 hours of experiential learning during four years (volunteer work, field exploration, internship, human service employment) and Spanish through the intermediate level. It is the responsibility of the student to complete all major and university requirements. Please refer to the university catalog for additional information regarding this major. Course title and content is subject to change. Not all courses are offered each semester or year. Please consult with your major advisor for the most current information. Students enrolled in the Lasallian Honors Program should consult the program director for the appropriate sequence of courses. Course descriptions + More (From the 2013-15 Catalog) A. Practice Core All of the following: HS111 - Introduction to Human Services (3 credits) Students trace the development of human services as a profession, identify employment options for human services professionals, and examine the various social problems to which human services professionals respond, including but not limited to child abuse, domestic violence, homelessness, immigration, mental illness, needs of the frail elderly, and substance abuse. Students complete 25 hours of service in an assigned local human services agency outside of class for the laboratory component of the course. Offered fall semester. HS211 - Interviewing and Assessment (3 credits) Students practice and demonstrate skills for intentional attending, development of therapeutic rapport, culturally competent interviewing and assessment, and solution- focused intervention planning. Offered spring semester. Prerequisite: HS111. HS306 - Case Management (3 credits) Case management is a vital professional skill. In this course students apply informal and formal assessment strategies to family units, identify and document problems in daily living as experienced by various populations, practice decision-making regarding ethical dilemmas, and document generalist case management services using professional practice standards. This course is also appropriate for psychology or criminal justice/corrections track majors. Offered spring semester. Prerequisite: HS211 or PY410. B. Research Core Three courses from the following: (Either PY290 or S250) PY290 - Experimental Psychology and Statistics (3 credits) This course is designed to give students an opportunity to develop knowledge and skills associated with research, including: reading research, collecting data, interpreting data analysis, and reporting results. Emphasis is placed on experimental design (e.g., comparisons among experimental and non-experimental approaches, threats to internal and external validity), interpretation of statistics (e.g., descriptive statistics, correlation, one and two-way ANOVA), reporting results, and research ethics. Prerequisites: PY111 and either ST132 or ST232. S250 - Logic of Analysis (4 credits) This course examines the major sociological perspectives in conjunction with an instruction in the logic and procedures of gathering information about social phenomena. The course covers topics such as: the logic of the scientific method, research design, hypotheses formation, theory and methods of scaling, and research analysis. Also offered as PS242. Offered every semester. Prerequisites: S110 and either ST132 or ST232. S350 - Field Methods (4 credits) This course offers a working experience in the purpose and tools of qualitative field methods. The course covers rapport, methods of observation, field notes, data coding and analysis, ethnography, focus groups and interviews, as well as an introduction to quasi-experimentation. Offered every semester. Also offered as PS342. ST132 - Reasoning with Statistics (3 credits) This course is designed to develop student facility in the use of statistical methods and the understanding of statistical concepts. The course takes a practical approach based on statistical examples taken from everyday life. Topics include: descriptive and inferential statistics, an intuitive introduction to probability, estimation, hypothesis testing, chi-square tests, regression and correlation. Appropriate technology is used to perform the calculations for many applications, and correspondingly an emphasis is placed on interpreting the results of statistical procedures. Credit is not granted for this course and any of the following: BU215, B392 or ST232. Prerequisite: mathematics competency. C. Human Development Core All of the following: B200 - Human Biology (2 credits) This course is designed for the student with little science in their backgrounds. Basic human biological principles are investigated with emphasis on nutrition, cancer, immunity, reproduction and heredity. Special consideration is given to current advances in medicine and associated bio-social issues. Two lectures are held each week. Offered fall semester and in alternate spring semesters. Concurrent registration in B201 is required. B201 - Human Biology Laboratory (1 credit ) These laboratory sessions are designed to reinforce concepts presented in B200. Emphasis is given to study on the digestive, immune, excretory, circulatory, and reproductive systems. The lab meets two hours once a week. Offered fall semester and in alternate spring semesters. Concurrent registration in B200 is required. PY111 - General Psychology (3 credits) General Psychology provides an overview of the methods, fundamental principles, and major perspectives which define the discipline of psychology. Intrapersonal and/or interpersonal psychological processes involved in the biological basis of behavior, sleeping and dreaming, conditioning and learning, cognition, lifespan human development, abnormal psychology, and psychological treatment. Classical and contemporary research and perspectives including the biological, cognitive, behavioral, psychodynamic, humanistic, sociocultural and evolutionary perspectives are explored. Students are actively involved through application, interactive exercises, simulations, and projects. PY211 - Developmental Psychology (3 credits) This course explores the study of growth and development across the life span. Students are introduced to the reciprocal nature of biological, cognitive, social and cultural factors on the developing person. This is a research- based introduction to understanding the expression of development in everyday life as it extends to family, friendship, youth ministry, school, neighborhood, sports, health care, and social services. Prerequisite: PY111. D. Three upper-division courses approved by the program coordinator from the following courses: B305 - Human Anatomy with Laboratory (4 credits) This course explores the design and structure of the human body. Lectures present cellular and histological features of the body systems. Laboratory dissections explore gross anatomic features and the three dimensional relationships of structures particularly relevant to the health sciences. Body structures forming superficial features, those visualized by diagnostic imaging techniques and those relevant to kinesiology are empathized. The class meets for two lectures sessions and two two-hour labs weekly. Offered fall semester. Prerequisites: B110/111 and B120/121 B306 - Medical Terminology (2 credits) This course is an organ systems approach to learning and understanding medical terms. A word building programmed learning format is utilized to understand Latin and Greek prefixes and root words from which our English medical words originate. Common medical abbreviations and case studies are also incorporated into the course. The class meets for two discussion periods weekly. B313 - Physiology with Laboratory (4 credits) This course explores the functions of the body systems of humans. The interrelationships of organ systems processes to maintain homeostasis are emphasized. Laboratory sessions provide experiences with procedures and instrumentation to gather data that highlight the function of the body systems. Course topics are particularly relevant to the health sciences. The class meets for three lectures and one three-hour lab weekly. Offered spring semester. Prerequisites: B110/111 and B120/121 Recommended: C142/144. CJ302 - Correctional Processes (3 credits) This course examines the history, philosophies, and components of the American correctional system. It provides an overview of the origins of corrections and an introduction to the philosophical ideas with which specific correctional approaches are associated. The history, nature and recent developments of major institutions and programs that make up the current correctional system: jails, probation, intermediate punishments, prison, and parole are explored. Typically offered every spring semester. Prerequisites: CJ111 and S110. CJ352 - Drugs in American Society (3 credits) The primary objective of this course is to provide a comprehensive survey of the use and/or abuse of drugs in the United States and their impact on the criminal justice system. Special attention is given to the historical and sociological contexts in which drug laws have evolved and the implication of those laws on drug prevention policies. Typically offered every fall semester. Prerequisite: CJ111 or S110. H355 - U.S. Womenメs History (3 credits) This course is an examination of the image, roles, status, and activities of American women. In addition, gender issues are explored within their socio-political, cultural, and historical contexts. Special emphasis is placed on a comparative approach to the study of womenメs lives as they interact with race, class, and ethnicity. HS352 - Public Policy (4 credits) This course is devoted to a thorough review, analysis and evaluation of public welfare policy and at least one other topic. These topics may include but are not limited to the following: health care; environmental regulations; energy; consolidation of federal programs; affirmative action, etc. Special emphasis is given to the formulation, adoption, implementation, impact, and evaluation of public policy. Also offered as PS370. HS465-475 - Seminars in Human Services (1-4 credits) Specialized courses are offered in areas of particular interest to students and faculty. Examples include adoption, career and vocational development, immigration, substance abuse, and welfare reform. PH305 - Health Care Ethics (3 credits) This course provides a survey of some of the specific issues in health care ethics that are faced today by patients, providers, insurance companies and other constituencies in the health care arena. Such issues include: access ラ how are limited resources to be allocated? Informed consent - what information must patients possess in order to make reasonable and informed decisions about their health care? What compensatory obligations do providers have in the realm of informed consent? Funding ラ should the quality of health care vary by the means of the payer? Death ラ what is death? Also, should a patient have the right to choose the time and means of his or her death? Procedures and technologies ラ are all possible procedures and technical interventions morally defensible? PS332 - American Constitutional Law (3 credits) This course examines the social, philosophical and legal problems faced by the Supreme Court in translating the abstract language of civil liberties contained in the U.S. Constitution into concrete reality with an emphasis upon current problems and the evolving nature of the process. Offered spring semester. PS370 - Public Policy (4 credits) This course is devoted to a thorough review, analysis and evaluation of public welfare policy and at least one other topic. These topics may include but are not limited to the following: health care, environmental regulations, energy; consolidation of federal programs; affirmative action, etc. Special emphasis is given to the formulation, adoption, implementation, impact, and evaluation of public policy. Also offered as HS352. PY306-309 - Special Topics in Psychology (1 credit) These courses are designed to provide an opportunity to survey and discuss current trends and meet special need of students. Often the course includes both a theoretical and experimental emphasis. Topics vary from year to year depending on student and faculty interest. Prerequisites vary; consent of instructor is required. PY310 - Social Psychology (3 credits) Social psychology is the scientific study of how we perceive people and social events as well as how we influence and relate to one another. Areas covered include social cognition; prejudice, discrimination and stereotyping; the self; interpersonal attraction and close relationships; helping; aggression; attitudes and persuasion; conformity, compliance and obedience. Applications of social psychology to academics, the workplace, the media, and social relations are examined. Prerequisites: PY111, PY290, and either PY211 or PY220. PY370 - Personality Psychology (4 credits) Personality psychology examines the question, モWhat does it mean to be a person?ヤ This course includes historical ways in which we have tried to understand human persons. Classical personality theories including psychodynamic, cognitive, behavioral, trait and humanistic/existential are studied and evaluated. Contemporary research in personality areas such as attachment, temperament, the big five traits, and psychological well-being is studied and integrated with historical and classical approaches. Prerequisites: PY111, PY220, PY305, and PY310. PY470-479 - Seminars in Psychology (1-3 credits) These are courses of particular areas of psychology determined by faculty and student interest. Seminars offerings are predicated upon faculty availability. Topics have included: Psychology of Aging, Health Psychology, Positive Psychology, Psychology of Emotion and Sport Psychology. Prerequisites: PY111 and consent of faculty. S301 - Crime and Delinquency (3 credits) The study of deviant behavior as it relates to the definition of crime, crime statistics, theories of crime causation, and crime typologies are treated. The course covers topics such as criminological research, explanations of crime and delinquency, and the development of criminal justice policies. Offered every fall semester. Prerequisites: CJ111 and S110. S320 - Children and the State (4 credits) This course focuses on the concept of youth in contemporary society in terms of their behaviors, roles, experiences, and treatment. It does so within the context of the evolution and structural development of two major social institutions: the child welfare and juvenile justice systems. The course uses a sociological framework to emphasize the social, economic, and political realities of childhood in American society. Offered spring semester. S365 - Sociology of Aging (3 credits) The course is an attempt to provide an introduction to a field which is rapidly becoming one of the major areas of research in the social sciences and to bring about an awareness and knowledge about the process of aging. Old people and their needs, the impact of growing numbers of old people in our institutions, and the effect of these institutions on the aged is examined. Prerequisite: S110. S407 - Social and Political Movements (3 credits) This course examines the life cycle and impact of social and political movements, focusing on how the process of frame alignment, mobilizing networks and political opportunities shape movements. Also offered as PS334. Offered every other fall semester. Prerequisite: PS102 or S110. S425 - Ethnicity, Class and Gender (3 credits) This course provides numerous theoretical perspectives on ethnicity, class and gender along with a variety of activities which ensure each student an opportunity for developing an experience base with members of various ethnic, social class and gender communities. Also offered as CJ425. Prerequisite: S110. S443 - Sociology of the Family (3 credits) A comprehensive study of the family and associated institutions, theories and research in American family structure and function, cross-cultural comparisons, family interaction dynamics, disorganization, and change is included. Prerequisite: S110. E. Section E or F Both of the following: HS489 - Thesis Development (1 credit) In this course a student begins work on the thesis requirement. The student is expected to select a relevant topic, review relevant scholarly literature and design a research project independently with mentoring by the academic advisor. Prerequisites: completion of research core of the major and consent of the academic advisor. HS490 - Research in Human Services (2 credits) In this course the student is expected to complete the research project designed in HS489. The student develops the project independently with mentoring by the academic advisor. Prerequisite: HS489. F. Section E or F All of the following: HS495 - Internship Preparation (0-1 credit) Taken the semester before the student completes an internship, students work individually and as a group to evaluate internship readiness; identify possible internship sites; initiate interviews with prospective internship supervisors; review the literature about the population to be served; and develop learning contracts for secured internship sites. Students must meet university internship eligibility requirements. Graded pass/no credit. Prerequisites: completion of HS111, HS211 and HS306. HS496/497 - Human Services Internship (1-17 credits) This off-campus experience provides qualified juniors or seniors with opportunities to participate as members of established human services site teams. The studentメs academic advisor, in conjunction with the Universityメs Career Services office and on-site professionals, provides supervision and guidance during the internship. Prerequisites: B200, B201, HS111, HS211, HS306, HS495, PY111, and PY211. Co-requisite: HS498. HS498 - Internship Integration (2 credits) Students engage in evidence-based self-assessment and peer review as they synthesize professional knowledge and skills during the internship. This course is offered with a distance-learning experience to accommodate students completing geographically-distant internships. Co-requisite: HS496/497. A student may complete the internship requirement with an approved semester study abroad program; consult with the program coordinator to discuss options. Human services majors are strongly encouraged to complete at least 400 hours of related service work through volunteering, service learning, field experience and internships, and to achieve basic proficiency in Spanish or American Sign Language.


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Encyclopedia of Jazz Musicians
Ess, Gene (Gene Ichita Shimosato)
Ess, Gene [Gene Ichita Shimosato], guitarist, composer, producer, teacher; b. Taipei, Taiwan, 31 July 1965. Moved to Tokyo, Japan at less than 1 year of age. Grew up on a U.S. Air Force base on Okinawa, Japan. Moved to Virginia, U.S. at 17 years of age. Attended Berklee College of Music in Boston, MA. (1984-1989). Moved to New York City, NY 1991 - current. Became citizen of United States, March 24, 2000. Mother, Kazuko Shimosato (b. 1936) resides in Okinawa, Japan. She is a classical piano instructor. Gene has 2 younger brothers, Kenji Shimosato (b. July 4, 1968) and Kohta Shimosato (b. January 4, 1975). Gene is married to Julia Saiz-Shimosato (b. November 8, 1969) and currently resides in the East Village, NYC.
Ess brings his award-winning musicianship from a very diverse background. He grew up playing the classical piano, due to his mother being a classical pianist and a well known piano instructor on the island of Okinawa; his early years were filled with the classical sounds of Beethoven and Chopin. Simultaneously, Gene was receiving a mix of influences: he was exposed to the indigenous music of the island, and -growing up in a US Air Force Base- to the pop and jazz music coming out of the clubs for the American soldiers. All this amounted for an early obsession with music.
Gene performed in clubs all around Okinawa at the age of 14, and was considered a child prodigy by musicians and by his music instructors. Not satisfied, Gene left to George Mason University, where he pursued classical music studies, after high school graduation. There he studied with Larry Snitzler, a prominent concert guitarist who was once Andres Segovia's disciple. Gene also began studying orchestral composition under Dr. Glenn Smith.
Gene received a scholarship to attend the prestigious Berklee College of Music in Boston, where he continued his musical quest and was heavily influenced by the music of John Coltrane. During those years, Gene continued performing and started leading his own bands that included, among others, pianist Danilo Perez. After studies with Jerry Bergonzi and Charlie Banacos, Gene graduated from Berklee with honors in 1989 and moved to New York in 1991.
Moving to New York in 1991 proved fruitful. Gene's first 'gig' in New York was at Condon's. In the band, together with Gene, were Rashied Ali, Reggie Workman, Eddie Henderson, Antoine Roney, and Sonelius Smith. Gene's collaboration with Rashied Ali has continued to this day. Gene has performed his music in Europe, Asia, and the United States, both as leader of his own group and as a sideman. Some of the musicians he has performed with are Carlos Santana, Rashied Ali, Ravi Coltrane, Danilo Perez, Ray Appleton, Santi Debriano, Gene Jackson, Al Foster, Harvie S, Reggie Workman, Slide Hampton, Greg Tardy, Archie Shepp, Eddie Henderson, Kenny Davis, and Yamashita Yosuke.
GSQ (unissued, recorded 1992); Prayer for September (1995); Sunrise Falling (2003)
As sideperson:
Bob Malone: First Flash of Success (1988); Rashied Ali: No One In Particular (2001)
Spotlight Feature. Guitar Player Magazine. January, 1991.
Auditions Feature. Downbeat Magazine. December, 1990.
Four Star review, Prayer for September CD. Jazz Life Magazine. November, 1995.
Four Star review, Prayer for September CD. Swing Journal Magazine. October, 1995.
Finalist, Reader's Soundpage Competition. Guitar Player Magazine. July, 1989.
Jim Hall Award, Berklee College of Music. 1988 and 1987.
Downbeat Outstanding Classical Soloist Award. Downbeat Magazine, June, 1985 for Gene's performance of Lennox Berkeley's 'Theme and Variations'
Long interview at www.allaboutjazz.com/iviews/gshimosato.htm (2002)
Contact information:
email: email@example.com
tel: 212-375-9848


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Kids on Cholesterol Drugs: American Academy of Pediatrics Goes Bonkers!
Several of these drugs are approved for use in children and data show that increasing numbers are using them.Well, if it wasn't official before. It sure is now! American medicine has gone nucking futs! No doubt, drug companies have their hands in this—it reeks of their stink. Now, I also read about this on the Well blog. Check this out:
"If we are more aggressive about this in childhood, I think we can have an impact on what happens later in life ... and avoid some of these heart attacks and strokes in adulthood," Daniels said. He has worked as a consultant to Abbott Laboratories and Merck & Co., but not on matters involving their cholesterol drugs.
Drug treatment would generally be targeted for kids at least 8 years old who have too much LDL, the "bad" cholesterol, along with other risky conditions, including obesity and high blood pressure.
For overweight children with too little HDL, the "good" cholesterol, the first course of action should be weight loss, more physical activity and nutritional counseling, the academy says.
Pediatricians should routinely check the cholesterol of children with a family history of inherited cholesterol disease or with parents or grandparents who developed heart disease at an early age, the recommendations say. Screening also is advised for kids whose family history isn't known and those who are overweight, obese or have other heart disease risk factors.
The guidelines give no guidance on how long a child should stay on drug treatment. But they do say the first goal should be to lower bad cholesterol levels to less than 160 milligrams or possibly as low as 110 milligrams in children with a strong family history of heart disease or other risk factors like obesity.Clearly there is plenty of merit behind this recommendation—give me a break!
Because statins have been around since only the mid-1980s, there is no evidence to show whether giving statins to a child will lower the risk for heart attack in middle age.
UPDATE: More from Dr. Fuhrman: My Thoughts on Giving Children Cholesterol Drugs.


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with our special guest
Randy E. Barnett
- Austin B. Fletcher Professor of Law, Boston University School of Law
Senior Fellow, Cato Institute.
Friday, February 11, 2005
12:00 noon
Brownstone, 1707 Hillsborough Street, Raleigh, NC
Price: $20
During his second term, George W. Bush will have the opportunity to nominate one or more Supreme Court Justices. The debate surrounding how these nominees will interpret the U.S. Constitution will be fierce.
Join us for a look inside this contentious controversy with one of the nation's leading constitutional law scholars, Randy Barnett.
In his new book, Restoring the Lost Constitution, Barnett, tells us that the U.S. Constitution found in school textbooks and under glass in Washington is not the one enforced today by the Supreme Court.
Barnett argues that since the nation's founding, but especially since the 1930s, the courts have been cutting holes in the original Constitution and its amendments to eliminate the parts that protect liberty from the power of government. From the Commerce Clause, to the Necessary and Proper Clause, to the Ninth and Tenth Amendments, to the Privileges or Immunities Clause of the Fourteenth Amendment, the Supreme Court has rendered each of these provisions toothless. In the process, the written Constitution has been lost.
Before entering teaching, Barnett was a criminal prosecutor for the Cook County State's Attorney's Office in Chicago, where he tried many felony cases. Most recently, he was a lead attorney in Raich v. Ashcroft, the Supreme Court case that considered the legality of medical marijuana.
Register now for this most important discussion!
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The Dinner Party by Judy Chicago
39 Guests and the 999 Women of AchievementPre-History to Decline of Graeco-Roman Civilization
1. PRIMORDIAL GODDESS, symbol of all emergent life representing:
2. FERTILE GODDESS, symbol of fertility representing:
3. ISHTAR, GREAT GODDESS OF BABYLONIA, giver and taker of life representing:
4. KALI, Indian devourer/destroyer goddess representing:
5. SNAKE GODDESS, embodiment of psychic vision and oracular divination representing:
6. SOPHIA, abstract female symbol of Wisdom representing:
7. AMAZON representing:
8. HATSHEPSUT, Egyptian pharaoh of XVIII dynasty representing:
9. JUDITH, Hebrew heroine representing:
10. SAPPHO, Greek poet, fl. 600 B.C. representing:
11. ASPASIA, Greek scholar and philosopher, 470-410 B.C. representing:
12. BOADACEIA (BOUDICCA), British warrior queen, lst c. A.D. representing:
13. HYPATIA, Roman scholar, mathematician, and philosopher, 370-415, representing:
Beginning of Christianity to Reformation
13. MARCELLA, teacher and founder of Christian community of women, 325-410, representing:
16. THEODORA, Byzantine Empress, 508-548, representing:
17. HROSVITHA, German poet and dramatist, 935-1002, representing:
18. TROTULA OF SALERNO, Italian physician, author, professor, d. 1097, representing:
19. ELEANOR OF AQUITAINE, Queen of France and England, 1122-1204, representing:
20. HILDEGARDE OF BINGEN, abbess, scientist, scholar, musician, composer, visionary, 1098-1179, representing:
21. PETRONILLA DE MEATH, burnt as a witch, d. 1324, representing 300,000-9,000,000 (estimates vary) women exterminated as witches 13th-17th C. including:
22. CHRISTINE DE PISAN, professional author 1363-1431, representing:
23. ISABELLA D'ESTE, Renaissance princess, scholar, patron, musician, 1474-1539, representing:
24. ELIZABETH R, queen of England, scholar, poet, 1533-1603 representing:
25. ARTEMISIA GENTILESCHI, painter, 1590-1642 representing:
26. ANNA VAN SCHURMAN, scholar, artist, author, theologian, 1607-1678 representing:
Seventeenth Century-Present
27. ANNE HUTCHISON, midwife, teacher, heretic 1591-1643, representing:
28. SACAJAWEA, guide on Lewis & Clark expedition, 1787-1812, representing:
29. CAROLINE HERSCHEL, astronomer, 1750-1848, representing:
30. MARY WOLLSTONECRAFT, novelist, feminist writer and theoretician, 1759-1797, representing:
31. SOJOURNER TRUTH, abolitionist, feminist, 1797-1883 representing:
32. SUSAN B. ANTHONY, feminist, author, 1820-1906 representing:
33. ELIZABETH BLACKWELL, physician, founder of medical school, 1821-1910 representing:
34. EMILY DICKINSON, poet, 1830-1886 representing:
35. ETHEL SMYTH, composer, 1858-1944 representing:
36. MARGARET SANGER, convener of International Birth Control Congress, president of Planned Parenthood, 1879-1966, representing:
37. NATALIE BARNEY, writer, aphorist, lesbian feminist, 1876-1972 representing:
38. VIRGINIA WOOLF, novelist, critic, feminist theorist, 1882-1941 representing:
39. GEORGIA O'KEEFE, artist, 1887-1980 representing:
|Go to: Links
for Judy Chicago and other Wild Women
Return to: Wild Women of the 20th Century
Return to: LIT 2380


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Posts Tagged 'Hannah Bools'
On This Day … 23 July
1866 – Elizabeth BITTLES was born in Lemont, Illinois 149 years ago to Margaret & Stewart Bittles. (2nd great-grandaunt -p)
1872 – Harriet DAVIS was born in Ypsilanti, Michigan 143 years ago. (wife of John ASSMANN, 1st cousin 4x removed -m)
1876 – Hannah GARLICK Bools died 139 years ago in Lockport, Illinois at 54 years old. (3rd great-grandaunt -p)
1879 – Emma Denna HOENINGHAUSEN (25) married Herman KOEHLER (30) in Detroit, Michigan 136 years ago. (1st cousin 4x removed -m)
1890 – Joseph DETTLOFF (41) married Mary EBNAL (24) in Detroit, Michigan 125 years ago. (2nd great-granduncle -p)
1892 – Catherine HENGSTEBECK Kessler died 123 years ago in Detroit, Michigan at 38 years old. (wife of William KESSLER, 2nd great-granduncle -m)
1914 – Margaret REID Bittles died 101 years ago in Lemont, Illinois at 86 years old. (wife of James BITTLES, 3rd great-granduncle -p)
1946 – Nicholas KAUTHEN died 69 years ago in Bremerton, Washington at 71 years old. (2nd cousin 3x removed -m)
1960 – Elizabeth RAASS Allen died 55 years ago in Detroit, Michigan at 80 years old. (1st cousin 4x removed -m)
If you have information about any of these people or if you would like more information, please contact me!


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Brand new Justin Alexander dress, style 8643. Never worn or altered, still in its original bag! Size 6.
- Alterations: No alterations to dress, no damage. Brand new and clean.
- Preservation Method: Stored in its original bag from the bridal shop.
- Terms of Sale: All Sales Final
- Original Owner: Yes
- Has Original Receipt: Yes
- Location: Wethersfield, CT
- Will Ship to: Anywhere at Buyer Expense
- Payment Methods Accepted: Escrow.com
Please read our BUYER'S GUIDE before purchasing a dress online.


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The LaGrange County 4-H Fair Association has chosen Cleo Hartzler as the grand marshall for the 60th Annual LaGrange County 4-H Fair.
Kristin Witham will be awarded the Waddell and LIFE scholarships at Lakeland High School during an award event scheduled for 7 p.m. on Wednesday, May 22.
Brennen helps team place second at meat evaluation competition
Richard D. Clark, 83, died Sunday, May 12, 2013 at Coventry Meadows in Ft. Wayne, Ind.
Meredeth Ann Wittrig, 79, Topeka, died Saturday, May 11, 2013 at Parkview LaGrange Hospital.
Westview went 1-1 in the Bremen Invitational softball tournament played this past Saturday.
Westview improved to 7-1 in the NECC baseball standings last Thursday night with a 12-3 thrashing of host Churubusco.
The Prairie Heights varsity baseball team smacked 42 hits and scored 46 runs in a doubleheader demolition of host Bethany Christian Saturday.
Prairie Heights went 2-2 in varsity softball action over the weekend, moving its season record to 7-12.
Lakeland and East Noble split a varsity baseball twin-bill Saturday in LaGrange.
Westview took second place in a varsity baseball tournament played Saturday at Culver Academy.
Lakeland placed third out of 12 teams in Saturday's Angola Invitational boys golf tournament held at Glendarin Hills Country Club.
A presentation about one of the Civil War's most daring women will be given during Civil War History Day, set for Aug 10 at the LaGrange County Courthouse.
A multi-agency task force executed search warrants on three homes in LaGrange County Thursday morning, May 9, starting around 6 a.m.


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First Windows Mobile 6.5 images surface
Since Steve Ballmer mentioned it, the 2009 launch of Windows Mobile 6.5 is not a secret anymore. However, Mr. Ballmer said nothing about the goodies that WM 6.5 will bring to us, so for the moment we can't say if it will be a major upgrade from WM 6.1 or just a minor one.
Luckily for the fans of Microsoft's mobile OS, two screenshots with Windows Mobile 6.5 have just leaked on the Web, via Smartphone France.
If we're to judge upon these images only, the look of Windows Mobile 6.5 is definitely nicer than the one of WM 6.1.
There is a hexagonal menu in this WM 6.5, and I don't think there's any other OS / mobile platform to have such a menu.
Of course, these screenshots might actually be fake, especially since that colored Windows logo doesn't look like it's genuine. But the French website mentioned above says that the source of the images is a "reliable" one, so I guess we should, for the moment at least, believe it.
Now, until something more official regarding WM 6.5 comes out, we can only hope that everything about it will be as cool as it looks to be now.


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Forever Paws, a non-profit, no-kill shelter located in Fall River, Mass. began production of a new television show called "Straight from the Paws" to be aired on Fall River Community Television, according to Wicked Local.
The show, which began in March, features episodes about adoption, pet care, grooming, training and the shelter as a whole. "Straight from the Paws" also highlighted the veterinarian assistant program at Bristol Community College and how it helps the shelter.
Other episodes have focused on volunteer opportunities and the Board of Directors.
"Straight from the Paws" airs Wednesday nights, once a month, at 9 p.m. on channel 95 in Fall River. A schedule for Fall River Community Television can be found in the Herald News or at www.frmedia.org. Catch past episodes here.
Forever Paws takes in animals to find them new homes when other shelters are overcrowded. The shelter cares for the homeless, abused and unwanted animals in the Fall River area.
In the news:
Nearly a dozen pit bulls rescued from horrific conditions in Lawrence, MA
Deer dies jumping through window of Cohasset home
Westborough family ordered to take down missing dog signs
Florida man drowns saving his dog's life


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absolutely breaktaking. its really delicious. its light great for a diet and it reminds me of some type of pie or something with a side of icecream all by just adding the grilled peach:
I would recommend to skin the peach and cook it down until soft. It can be really difficult to eat and not cooked enough and will melt the icecream quick while you fight to get the peach out of the skin. skin it and grill til soft then scoop out ice cream.. coconut optional just delicious without.


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At time 0, a cell culture starts with one red cell. At the end of one minute, the red cell dies and is replaced by 2 red cells with probability $\frac{1}{4}$, with 1 red and 1 white cell with probability $\frac{2}{3}$, and with 2 white cells with probability $\frac{1}{12}$. Each red cell lives for one minute and gives birth to offspring in the same way as the parent cell. Each white cell lives for one minute and dies without reproducing.
I need to find a probability generating function for this. I don't have any problems with finding the pgf; however, I am unsure what the offspring distribution is to be used in the pgf summation. What I am thinking is this:
Let $X$ be the number of off-springs. Then $$ \mathbb{P}(X=0) = \frac{1}{12} \qquad \mathbb{P}(X=1) = \frac{2}{3} \qquad \mathbb{P}(X=2) = \frac{1}{4} $$ I am unsure if this is correct because if we have 2 red cells, then won't the total number of offspring be 4? So don't we need an $X=4$ case?
If I am correct with my distribution, then the pgf will be $\frac{1}{12} + \frac{2}{3} s + \frac{1}{4} s^2$.
Thanks for the help.
I am trying to figure out the probability that the entire culture dies out (using the pgf). I am not exactly sure what random variable I need for that...


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NEW YORK (AP) -- Syracuse and Mississippi State both struggled in
the first half. Hakim Warrick made sure Syracuse had a much better
final 20 minutes.
Warrick scored 17 of his 21 points in the second half and the
Orange (No. 6 ESPN/USA Today; No. 5 AP) beat Mississippi State (No. 14 ESPN/USA Today; No. 12 AP) 71-58 Thursday
night in the semifinals of the Coaches vs. Cancer Classic.
"We got him the ball. We made a conscious effort to get him the
ball," Syracuse coach Jim Boeheim said of the difference in
Warrick in the two halves. "We showed patience and got much better
Syracuse (3-0) will play Memphis (No. 23 ESPN/USA Today; No. 24 AP) on Friday night in the
championship game at Madison Square Garden. The Tigers (3-0) beat
Saint Mary's 81-66 in the other semifinal.
Syracuse and Mississippi State (2-1) were tied 25-25 at
halftime. Syracuse had the better shooting half, hitting 29.4
percent to the Bulldogs' 26.5. The Orange were 1-for-8 from 3-point
range, Mississippi State was 1-for-9.
The matchup of preseason All-Americans was even, too, and not
very good. Warrick had four points on 2-for-5 shooting and Lawrence
Roberts of the Bulldogs, playing for the first time this season,
had two points and missed all five of his shots.
Warrick, a 6-foot-8 senior, had six points in Syracuse's 11-0
run to open the second half and the Orange stayed about that far in
front the rest of the way.
"I think once we all got going it was really us," Warrick
said. "That's what got me going."
Gerry McNamara missed his first six 3-point attempts before
hitting two around a dunk by Warrick on his alley-oop pass to give
the Orange a 56-43 lead with 9:18 to play.
Warrick had 10 rebounds and McNamara finished with nine points
and seven assists for the Orange, who went 21-for-31 from the field
in the second half (67.7 percent).
"I thought we executed about as well as we could in the second
half," Boeheim said. "What did we shoot? Sixty-seven percent.
Yeah, that's good. We executed better, got good movement and better
shot selection."
Roberts, the Southeastern Conference player of the year last
season, missed the Bulldogs' opener because of an NCAA suspension
over payment to an NBA pre-draft workout. He missed the second game
recovering from a broken nose in practice last week.
Playing with a face mask, Roberts finished with nine points and
12 rebounds. He was 2-for-9 from the field and never looked
comfortable in his 28 minutes.
"We knew he would play we just didn't know how much,"
Mississippi State coach Rick Stansbury said of Roberts. "He hasn't
practiced and we couldn't expect that much out of him but he still
gets us 12 rebounds. It's his presence out there that helps the
team. He missed some chippies he normally makes. Unfortunately for
us he had to play that much tonight."
Shane Power had 18 points for Mississippi State, which shot 31.3
percent for the game (20-for-64).
"It was that first 4, 5 minutes of the second half. That was a
big spurt," Stansbury said. "In the first half we did a good job
on Warrick and McNamara. Then Warrick changed the emotion and
energy level of their team and we didn't show a lot of poise."
Syracuse is 3-0 all-time against Mississippi State with the last
meeting in the NCAA semifinals in 1996.


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Presently quilting, before that I knitted, before that I was a beader, and in the 70's & 80's I did counted cross stitch, leatherwork, watercolor painting, colored pencil/pastels, needlepoint.....I've never met a craft I didn't want to spend money on!
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The city of Atlanta's Central Park and Renaissance Park are located in the Old Fourth Ward (west) near the Atlanta Civic Center at the intersections of Central Park Place, Pine Street, and Piedmont Avenue.
Central Park provides 17 acres of recreational amenities including walking paths, sport fields, playground, basketball and tennis courts, plus an indoor recreational center.
Renaissance Park offers a 5 acre tree covered canopy, walking paths, and shaded hilltop views.
Escape to the city center.


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More New and Used
from Private Sellers
Note: Supplemental materials are not guaranteed with Rental or Used book purchases.
The Church, Our Story
ISBN13:by Driedger, Patricia Morrison
Ave Maria Pr
Questions About This Book?
Why should I rent this book?
Renting is easy, fast, and cheap! Renting from eCampus.com can save you hundreds of dollars compared to the cost of new or used books each semester. At the end of the semester, simply ship the book back to us with a free UPS shipping label! No need to worry about selling it back.
How do rental returns work?
Returning books is as easy as possible. As your rental due date approaches, we will email you several courtesy reminders. When you are ready to return, you can print a free UPS shipping label from our website at any time. Then, just return the book to your UPS driver or any staffed UPS location. You can even use the same box we shipped it in!
What version or edition is this?
This is the Student edition with a publication date of 10/31/2005.
What is included with this book?
- The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any CDs, lab manuals, study guides, etc.
- The Used copy of this book is not guaranteed to include any supplemental materials. Typically, only the book itself is included.
- The Rental copy of this book is not guaranteed to include any supplemental materials. You may receive a brand new copy, but typically, only the book itself.
- The eBook copy of this book is not guaranteed to include any supplemental materials. Typically only the book itself is included.
Constructed around the themes that represent Church practice and belief, with each theme containing a historical component. Perfect for a semester or year-long study.


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Chicken is an inexpensive choice for dinner and one that is healthier than its counter entrée choices such as beef. Chicken contains fewer calories and is enjoyed by just about everyone in the family. Giving chicken breasts a little facelift from the usual broiled, baked or boiled cooking methods will give chicken a new taste, look and texture to enjoy. The fruity accompaniment adds flavor, a serving of healthy fruit to your diet while the lemon packs a ever so light tang to the dish. Crock pot cooking is so easy; just set it up and forget it until the timer goes off. By then you'll have all the little things you need to do done for the day and have time to make side dishes to join your sweet and tangy pineapple chicken dinner.
- 3 pounds of chicken breasts
- 2 tablespoons of canola oil
- 1 (8 ounce) can of unsweetened crushed pineapple, do not drain
- 1 cup of brown sugar, packed
- ½ cup of honey
- ¼ cup of lemon juice
- ¼ cup of melted butter
- 2 tablespoons of mustard
- 2 teaspoons of soy sauce
- Place the chicken breasts in the crock pot first and cover with the remaining ingredients.
- Cover the crock pot and cook the chicken entrée on low for 3-4 hours or until chicken is cooked through.
- Remove chicken from crock pot when cooked and place it on a serving platter.
- Use a colander to strain the liquid from the crock pot reserving the cooked and crushed pineapple.
- Spread the pineapple over the chicken and serve while hot.
- Enjoy!
- To create a chicken pineapple gravy reserve 1 cup of the liquid and place it in a sauce pan. Heat on a medium heat and stir in 2 tablespoons of corn starch and bring the liquid to a boil. Stir constantly until the fruity gravy thickens and pour into a tureen for anyone who wants a little extra juice on their chicken dinner.
© 2014 Beverly Mucha / All Rights Reserved
Jackson residents can shop at any of these local grocery stores: Pick'n Save or Wal-mart for all the ingredients needed for this recipe.
Never miss another recipe, cooking tip or news story again! Subscribe to Beverly Mucha @ Jackson Cooking Examiner and receive a free notification every time something new is published.
You can also follow Beverly on Facebook, Twitter and Pinterest.
More reading topics from this author:
Happy Reading!


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I resisted this ultra-classic cutie for a long time, despite my own whisperings and the less-subtle persuasion of my good friend Ken Smith, who really enjoys his Argus AF (focusing model). I finally succumbed after a now-retired colleague from work -- and fellow phototgrapher -- found a couple of old Argus cameras in a box in his rafters, relics from the house's previous owner. He asked if I would clean them up so that he could try to use them and of course I agreed. One was an original A and the other an original C. So on a Friday night during a repeat viewing of Men in Black on DVD I carefully removed 40 years of dirt from the two classics, made them pretty and tested them. And then suddenly realized I had to have an A of my own. Small, light, classic Art Deco styling -- what's not to like?
The Argus A's place in history is secure. It was a radio company's inspired foray into consumer-level camera-making, which proved so popular that International Radio Corporation sold off its radio manufacturing business to concentrate on camera-making as 'International Research Corporation', then rebranding to the name of their flagship (pun fully intended) Argus line. The A's runaway success was largely due to its cheap price in tough economic times -- this Leica-A inspired plastic classic (actually bakelite) basically brought 35mm photography to the masses.
The A was updated into other models over the years -- focusing capability was added at one point (AF), an extinction meter at another (A2) -- a few different shutters were used as well, from no-name to Ilex Precise to Prontor. Apparently I'm lucky to have a slightly improved later A that has a double-sprocket guide wheel, the only way to fly. (I didn't know there was any other kind!) A spring-loaded pressure plate would have been nice, though that didn't come till later.
As with many of the old Argi, because of their ubiquity and antiquity, the price is usually still nice -- I won mine in online auction for $5, which included a nice leather case, usually a sign of a well-protected instrument. Emphasis on the "usually". Sure, I could have held out for the more collectible AF (focusing A) but I thought that for convenience's sake I'd be more likely to use a fixed-focus lens. Besides, I can always get another ;)
TURNS OUT though that this isn't the fixed-focus lens I thought it was, it's a zone focus lens in two zones, nominally 6 to 18 feet and 18 feet to infinity according to the manual. HOWEVER that must mean stopped-down because a check with a loupe and glass at the film plane makes it seem more like 5 feet to 10 feet and 10 feet to infinity... wide open anyway. The first zone (NEAR) is with the lens extended and locked in place. The far zone is with the lens extended and NOT locked. Kind of opposite of what you'd expect. Important to know!
Speaking of the lens, this three-element 'Argus Anastigmat' is surprisingly good, despite being uncoated and showing occasional vignetting. My question - where did the design come from? It's one thing for someone with plastic moulding experience to come up with an inspired design for a new camera, but how does a former plastics company come out of the starting gate with a fairly complex and cutting-edge optical formula? Food for thought.
Another odd thought - the manual shows a man holding this camera with the viewfinder ON THE BOTTOM, saying it was the recommended way of holding the camera to 'the bony part of the face'. I don't recommend that myself. Hard enough to hold the thing still while you press the shutter lever!
PS - the rest of the story is that my Argus-endowed colleague paid me in film for my efforts, so of course I had to use some of that (HP5 plus) to break in my own Argus A. Turns out however that it's best to match a slow lens-shutter combination with slow film to avoid gross overexposure, you'd think I would have remembered that from my Adventures with Photax.
Pretty filthy, with tarnished brass, cloudy glass, a missing screw and hardened foam. Gee, what was I expecting for my $5 anyway? Cleaned up all the tarnished metal parts with Circle 7 polishing compound (great stuff!), including the back; cleaned the glass with Windex, and replaced the hardened foam in the back door with a 1cm x 5cm piece of neoprene from a mousepad. Replaced the nameplate screw with one from a busted Petri. The good news: the ancient shutter seems pretty good, the apertures stop down apparently correctly, and the glass looks clear now that it's clean.
Tips & Tricks
See above for info regarding the two-zone focus. My advice is to check the ranges yourself with a loupe and ground glass to make sure the zones are where you think they are. Put a sticky note on the back of the camera if you need to.
The relatively slow lens and shutter mean that this camera is well-suited to slower films like 125 or below; the fact that the lens is uncoated means that colors may lack contrast and lens may be prone to flare. Luckily mine came with a R@RE-L@@K! press-on metal lens hood, that alone is probably worth the $5!
Related Links
- Ah, the manual! Thanks James!
- How to fix the Ilex Precise shutter
- Argus Collector's Group
- Cameraquest's take on this uber-classic
- Another interesting page on the Argus A


text: Overview Etihad Guest's coalition partner Smartax offers our members exciting opportunities to convert VAT refunds into Etihad Guest miles through a seamless process that does away with endless VAT-refund claim paperwork! We are launching our partnership in Ireland and will shortly be introducing this exciting opportunity globally. This partnership is valid at all outlets displaying the above signs.Participating outlets in Ireland: • Reiss. • Skunkfunk. • Kling. • Fat Face. • Eilis Boyle. • MoMuse Jewellery. • Bow. Next destinations for launch: UK and France!How it works:As an Etihad Guest member and a customer at a Smartax participating outlet, you simply pay for goods at the cash counter and your Etihad Guest card will be swiped. That's it! No forms to fill in and no need to worry about losing forms because your purchase history is safely stored on-line. Just keep your receipts safe as you may need them at the airport to show Customs. As an Etihad Guest member you not only save time and effort, the total value of your tax refund will be converted into Etihad Guest miles, bringing you closer faster to your next free flight on Etihad Airways. Note: Smartax has a strict privacy policy where consumer's names will not be sold for marketing mailing lists.


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Danielle Peazer Is A Big Hit On The X Factor Tour
Danielle Peazer is currently taking part in the X Factor UK tour with boyband hotties Union J and District 3, as well as James Arthur, Rylan Clark and more.
Chatting to Heat, she said:
"It's great to have Rylan back with us. He was nervous on the first day back because he was like 'oh my god, I have to learn a whole tour in one day' but he's so on it! He was amazing, he's so professional. He's the best, he works it."
Miss Peazer also said:
"He's tall but he has got the moves. Katie Price has even come down to see the show!"
And it seems that fans are loving her on the tour, with Payne-wife tweeting the following messages to fans over the last couple of days:
@perriesarmy thank you for the card! Lovely meeting u yesterday and again today lots of love xxx
And this…..love it, thank you xx pic.twitter.com/lqk8f2eq
Great time in Cardiff….. And thank you to the girls who gave me these presents! Especially the Lucozade xx pic.twitter.com/H4SQ5rSh
Here's a cool vid of Danielle dancing with James Arthur on the current X Factor UK tour:
And here's another treat for you – it's Danielle again on the X Factor tour, this time with Brit boyband District 3.
Is Danielle the most liked 1D girlfriend?
- http://www.facebook.com/annabeth.chase.3192
- http://twitter.com/TayBOfficial
- http://www.facebook.com/tania.maldonado.7
- http://twitter.com/TayBOfficial
- http://twitter.com/DanielaVelsquez


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Skydiving.com now has a network skydiving location serving Harvard and McHenry County in Illinois. Call Skydiving.com at 1-800-617-7948 for details, free information and specials on skydiving in Harvard, IL today!
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Sign up for our newsletter and receive updatesand specials on skydiving across America!


text:
Legal Writing Tutor
Ronda Fox, J.D./Ph.D.
Legal Writing Tutor
Ronda Fox, J.D./Ph.D.
Legal writing challenges even the most experienced writers entering law school. A J.D./Ph.D. (English)
and veteran Clinical Professor of Legal Writing and Advocacy at the University of Southern California
School of Law and Loyola Law School, I help students master this daunting genre.
Intensive, individualized attention is the best way for students to hone technical and analytical skills
and thus develop confidence as legal writers and future lawyers.
Entirely by email, legal writing assignments can be
• outlined and organized
• revised
• edited and proofread
with extensive comments so that students
not only complete their assignments
but also gain expertise.
The fee is arranged before work begins to
ensure that it fits each student's budget.
Email: email@example.com
Telephone: (310) 559-2522
Students are understood to have consulted school guidelines on obtaining editorial assistance.


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Category Archives: Just Creative
Podcast InterviewPosted on 16
'11 Jun
I was recently interviewed for the 12th episode of the CrueCast podcast show. If you wish to listen to the informal, conversational podcast, you can do so by clicking the previous link or listen to it on iTunes (view in [..]
Stats & Top Posts of 2010Posted on 21
'10 Dec
Last week I featured an article outlining the top 'all time' posts on Just Creative Design however none of the posts featured were actually from 2010. By request, here are the top 10 most popular posts, that were actually written [..]
Top 10 Most Popular Posts as of 2010Posted on 16
'10 Dec
The end of the year brings many round up lists, so here is my version, showcasing the top 10 most popular articles on Just Creative Design for 2010, based on stats from Google Analytics. 30 fonts to last a lifetime [..]
Back In ActionPosted on 26
'10 Jan
Some of you may have noticed this website and my other websites being down the past two weeks. Simply put, my old hosts did a runner on me… all of my websites and email stopped working and there was no [..]
20,000+ Subscribers – Comment To Win!Posted on 16
'09 Sep
© Shutterstock A journey of a thousand miles must begin with a single step. ~ Lao Tzu 20,000 subscribers… it's just another milestone but that's no reason to let it go unnoticed. With help from a few generous sponsors, Just [..]
News & ConnectionsPosted on 27
'09 Aug
Image courtesy of Shutterstock This is a general update of my future plans, articles I've written elsewhere and links to connect with me. It's Official – I'm Moving to NYC! I posted about my new job in NYC at Carrot [..]
Just Creative Design Goes MobilePosted on 22
'09 May
Thanks to the generosity and help from Mobify, Just Creative Design now has a mobile version. This means you can read JCD's articles on your iPhone or mobile device while having the pages & images load up to 7 times [..]


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Heat to have to start going by the numbers?
Erik Spoelstra's preference this season is to let his players play. Run. Pass. Settle into the continuity offense he began to install at Hurlburt Field.
But to play continuity, you have to have continuity. And with LeBron James out for at least another day, Dwyane Wade away from the team for a few days, and Mario Chalmers now saying he might not be back until the season opener, Plan B might become necessity.
That's Plan B as in Spoelstra standing, as he often had the first two years of his coaching career, and signaling in play calls.
"I think we're still going to be able to hit the ground running once we're 100 percent," forward Chris Bosh said after Friday's practice, one that featured neither James nor Wade (or even Chalmers).
"But we're not going to be able to flow into things. We're probably going to have to call more plays than usual."
In essence, that will have the Heat starting the season and, sometime thereafter, restarting the offense.
"Once we're 100 percent," Bosh said, "we'll have that flow in the game and make it a little easier on Spo. He's not going to have to call that many plays.
"He's not going to have to approach us like we're getting together. He'll just put us out there, and we'll take care of the rest."
Like the Heat did in the first three minutes of that first exhibition game, when Wade, James and Bosh all were healthy.
"It's important for team chemistry if we can get a game in together, all of us, that'd be great," James said of an eventuality that almost assuredly will not happen before the regular-season opener. "I would hope our whole 15, 17 guys can get one game in like we started off in the Detroit game."


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The graphic novel is a unique medium that integrates text and graphical representations into a set of panels that collectively convey a story. While the graphic novel is significantly different from the standard text-based novel in terms of content, for purposes of citation the graphic novel's APA reference should follow the standard book citation format.
In-Text Citations
The in-text citation for a graphic novel should follow the same rules as for a standard book. For a parenthetical citation, use the (Author, Year) format. For example: The graphic novel Maus (in italics) (Spiegelman, 1986) is a depiction of the Holocaust using cats as Germans and mice as Jews. A signal phrase should be formatted similarly. For example: In Spiegelman's Maus (in italics) (1986), the story of the Holocaust is depicted using cats as Germans and mice as Jews.
Reference List
A graphic novel reference listing should follow the same conventions as for a text-based novel: Author, A. A. (Year of publication). Title of work (in italics). Location: Publisher. For example: Spiegelman, A. (1986). Maus (in italics). New York: Pantheon Books.
Style Your World With Color
Explore Angelina Jolie's Favorite Color
See if her signature black pairs well with your personal style.View Article
What Does Your Color Choice Say About You?
Understand how color and its visual effects can be applied to your closet.View Article
Stay on Trend This Fashion Season
Explore a range of deep greens with the year's "it" colors.View Article
Emotionally Connect to Your Clothes
Create balance and growth throughout your wardrobe.View Article
- Purdue Owl: Reference List: Books
- Publication Manual of the American Psychological Association, Sixth Edition; American Psychological Association
Photo Credits
- Photos.com/Photos.com/Getty Images


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|UNT System: Resource magazine >> Natural killers
Imagine a future just a decade or so hence when a man hears the devastating diagnosis that he has leukemia.
But instead of being told he faces long months of debilitating chemotherapy and possible death, his doctor says, "Don't worry. We can cure you in a few days."
That's what Porunelloor Mathew, Ph.D., is working toward. An associate professor in the Department of Molecular Biology and Immunology at the University of North Texas Health Science Center at Fort Worth, Mathew believes his work activating the immune system's "natural killer" cells could someday lead to treatments that quickly hunt down and assassinate several kinds of cancers.
"All our work so far points to using one's own immune system to kill cancer cells relatively safely and without side effects," he says.
Mathew is associate director for basic research with the Health Science Center's Institute for Cancer Research. His work has been supported since 1992 by grants from the National Cancer Institute.
He also was named the Health Science Center's Outstanding Graduate Faculty
member for 2000 by the Graduate School of Biomedical Sciences and the
Graduate Student Association. It's the honor of which he's most proud.
A new cancer weapon
Mathew focuses on the 2B4 molecule, a receptor located on the surface of the natural killer, or NK, cells. NK cells are one of the three kinds of lymphocytes, the white blood cells that are a major component of the body's immune system. (The other two are T cells, which also kill virus-infected and tumor cells, and B cells, which produce antibodies.)
He learned that when the antibody to the 2B4 molecule activates the NK cell, the pumped-up killer cell suddenly can attack leukemia, lymphoma and melanoma — in mice and in human tissue cultures, anyway.
He expects to get patent approval for the single B cell antibody in early 2003 and then begin working with pharmaceutical companies on the three to five years of large-scale clinical trials that he hopes will result in NK cell mediated therapy to kill the three forms of cancers.
While emphasizing that nothing is certain until after clinical trials, John Ortaldo, Ph.D., chief of the experimental immunology laboratory at the National Cancer Institute, calls Mathew's work "an interesting approach."
"If it works, it would be a very significant advance in leukemia and lymphoma treatment," Ortaldo says.
Knocking out 'bad guys'
The immune system normally operates quickly and efficiently. NK cells constantly cruise the body, seeking out and destroying viruses, bacteria and parasites. When that isn't enough, backup T cells soon adapt to finish the job.
But cancer grows and spreads because the rogue cells are the body's own cells gone awry — native-born terrorists able to establish beachheads without suspicion, if you will — so the immune system doesn't always recognize them as it does outside invaders. By the time symptoms appear, cells often have spread, or metastasized, to distant parts of the body where they beget new cancers.
"Metastasis is the big problem in cancer," points out Kenneth Brunson, Ph.D., ICR director and research professor in the Health Science Center's Department of Molecular Biology and Immunology. "Very often, the patient already has undetectable spread of the cancer at diagnosis. More cancer patients die of the metastasis than the initial tumor."
Doctors strike back with the blunt weapon of chemotherapy, slaughtering healthy cells along with cancerous; surgery to excise the tumor, hoping cells don't escape; or relatively new anti-angiogenic drugs, which slow the growth of new blood vessels that the cancer needs to nourish itself.
And that's fine, for a while. The patient often goes into remission, but the few remaining cancer cells — those resistant to chemotherapy or those surgery didn't get — may grow to attack again in a few months or years. As Mathew explains, "Surgery or chemotherapy is rarely complete. About 70 percent of the time, you'll get the cancer again."
In fact, some 70 percent (about 21,700 people) of the approximately 30,800 Americans diagnosed with all forms of leukemia each year eventually succumb to the disease, according to American Cancer Society figures. In lymphoma, about 42 percent eventually die, or 25,800 of the 60,900 people diagnosed with new cases each year. Perhaps because it's more easily seen and removed promptly, only about 7,400 people die of melanoma yearly, or approximately 14 percent of roughly 53,600 new cases.
If Mathew's work holds up in clinical trials, his activated natural killer cells "have the potential to help us use the immune system to knock out not only the primary cancer, but also the metastatic cancers, which are the really bad guys of tumors," notes Brunson. The need for chemotherapy and radiation would be greatly reduced.
Of course, that potential is years away. Mathew to date has identified the critical 2B4 molecule, cloned human 2B4, generated an antibody to it and located the receptor molecule, or ligand, on the cancer cell, with which the antibody interacts like a key turning in a lock.
Once 2B4 and its antibody bind, "the NK cell becomes activated and kills cancer cells it normally cannot kill," Mathew says. "It kills quickly, wherever the cancer has spread."
Killing within hours
By "quickly" he means literally a few hours.
"In tissue cultures, the cells are killed in four hours, but the body is much more complex, so it would take longer. It could kill most of the cancer cells in two to three days in a person. This is realistic for some — but not all — cancers."
In practice, he envisions, doctors would draw blood to isolate the patient's own natural killer cells. The 2B4 antibody would be added to the NK cells and the two would be allowed to incubate for several hours so they would bind. The newly activated killer cells then would be injected into the patient on their seek-and-destroy mission.
"The beauty of our method is that it kills hidden cancer cells, and there are no side effects because you use the patient's own cells," Mathew says.
He works with leukemia, lymphoma and melanoma because they have the ligand to which 2B4 binds.
"If the cancer doesn't normally express the ligand for 2B4, this treatment doesn't work," he stresses.
Leukemia and lymphoma are also blood system cancers. Ortaldo says previous clinical studies showed activated killer cells have "minimal effect" on solid tumors, but "very possibly" the effect might be different in the blood system.
Mathew has also cloned two additional NK receptors, dubbed CS1 and LLT1, but hasn't yet identified their ligands and the activation mechanism. The goal is a treatment that targets every necessary cancer receptor.
He's confident his techniques will produce some cures before the decade is out because activated NK cells from healthy people wipe out cancers in human tissue culture.
Brunson adds, "Mathew has identified receptors that may be very effective in turning NK cells on. If you turn on the appropriate receptors, you can make the NK cells much better killers. It's fair to say that his lab is on the cutting edge of research today."
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