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|Lined Jacket Contest
August 1- 31 2012
The object of this contest is to create a lined jacket. The jacket must be wearable by a person, and must be lined, without exposed interior seams. The jacket must have sewn in sleeves.
In your review, pictures of both the inside and outside of the garment must be included. Details on the method you used for creating the jacket will be useful to those voting.
A jacket is a garment meant to be worn over another top. It has sewn-in sleeves and may any length from cropped (midriff) to full length (typically worn as a coat at that length). Being lined means at least 2 layers of fabric and no exposed seams. Bound or otherwise finished but exposed seam allowances do not qualify as lined for this contest. Small exposed but finished sections as a result of the lining technique are acceptable.
- Reversible jackets do not count as lined for this contest.
- Cloaks and capes are not jackets.
- Sleeves may be set-in, raglan, or dropped, but may not be cut-on (dolman or kimono).
- Any type of fasteners for the jacket opening can be used (buttons, zippers, frogs, hook and eye, ties) but are not required.
- Lining may be stitched down to the hem as is typical of a tailored jacket, or may be left loose as is typical of a tailored coat.
-Flip and stitched linings are acceptable.
- Jacket does not need to be tailored in style. It just needs to be lined
General Rules for all Contests:
All reviews must be entered for submission by 11:59 PM Eastern Time on the last day of the contest.
2. Patterns MAY be muslined prior to the start of this contest, however, fabric for contest garment may NOT be cut prior to the start of the contest. Fabric may be pretreated before the start of the contest.
3. Items intended for sale, or for which you were or will be paid to make, do not qualify for any contest, but items made for charity are welcome.
4. Unless otherwise stated in the rules, all reviews written for a contest entry must include a picture of the entry, preferably on a live model.
5. Interpretation of rules is subject to the discretion of the contest manager and the contest committee.
Contest Eligibility:
1. Any member of Pattern Review, either paying (FoPR) or non-paying, who's been a registered member on the site for 90 days prior to the start of a contest is eligible to enter.
2. Any member of Pattern Review, either paying (FoPR) or non-paying, who's been a registered member on the site for 90 days prior to the end of a contest is eligible to vote in a contest.
3. Any member who's won first place in a contest on Pattern Review that ended in the previous four-month period is ineligible to win another contest (during that four-month period). For this contest, first-place winners from the following contests are NOT eligible to win:
Pattern Stash 7/31/12
One Pattern, Many Looks 6/30/12
Natural Fabrics End date 5/30/12
One Yard Wonders End Date 5/15/12
Best Patterns End Date 5/15/12
RTW Contest End date 4/30/12
The first- and second-place winners will be decided by member vote.
First prize : Gift from Coats and Clark (worth $100)
2nd prize: Gift from Coats And Clark (worth $50)
Guidelines for Voting on Contests:
Because of the high quality of the garments we're seeing entered in PR Contests, we're setting forth some guidelines that may help you choose when voting. Consider how well the entry fulfills each of the following criteria in order to narrow down your votes:
1. Does the garment clearly reflect the pattern�s line drawing?
2. How well does the garment fit the criteria stated in the contest rules? How well does it fit the spirit of the rules?
3. Are the construction methods, including but not limited to seam finishes, lining techniques, etc, well suited to the design? To the fabric?
4. Is the fabric choice well suited to the design? Are the lining and interfacing choices appropriate?
5. Is the review complete and well written?
6. Taking into account the stated ability level of the entrant, how well does the garment fit?
7. Creative points. You may choose to give extra credit here for an entry that reflects additional creativity (embellishment, fabric choice, etc.) while staying within the nature of the original pattern.
8. Complexity of the project. Relate this to the skill level of the participant. If a participant is a beginner then a princess seam may get the same complexity level as an underarm gusset gets for an advanced sewer. This is purely subjective, but a complex garment might garner more points than a simple one if a tie-breaker is needed.


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Purple Pansies fundraising dinner at Casa Nuova Italian Restaurant in Alpharetta, GA. Event documentary and photography. Includes some information on Pancreatic Cancer. This event raised over $56,000 to research the cure for pancreatic cancer.
I've been involved in photography as an art for over thirty years. In high school, I was influenced by a photography teacher who instilled the purist principles of Edward Weston and Ansel Adams. I developed advanced skills in visualizing the tonal range of a setting and capturing images with available light. In the darkroom I experimented with a variety of chemical and temperature techniques for both film and print processing. At the University of Florida, my conservative and traditional perspective on photography as a visual medium was challenged by the thinking and works of Jerry Uelsmann, one of the early masters of photomontage, and guest lecturers like Robert Heineken (UCLA) whose montages embedded commercial erotica in highly unconventional images. Today my photography focuses on people - fashion, beauty, glamour, and fine art nudes.
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Inicia sesión o crea una cuenta para publicar un comentario.
Purple Pansies Dinner at Casa Nuova 2010 Publicado 22 de octubre de 2011
as i see it... Publicado 26 de agosto de 2011
A True Friendship Publicado 15 de diciembre de 2008
FRANCE IS NOT ITALY ! Publicado 28 de febrero de 2008
dA Love - Final Version Publicado 22 de enero de 2008
In Search of the Perfect Accessory Publicado 25 de diciembre de 2007
Because I Love You! Publicado 19 de diciembre de 2007
France is not Italy! Publicado 12 de diciembre de 2007

subset: commoncrawl


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Buy tickets for shows on performance day for 50% off at Cultural Connection, a project run by WLRN Public Radio and Television and the Theatre League of South Florida.
You must use a credit card and there is a total of $5 in service charges. Click here to see which shows are available at a discount and to buy tickets. The site updates every day at midnight with the next day's offerings. You must buy by 5 p.m. the day of the show.


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LG Connect 4G and Samsung Galaxy Attain 4G announced by MetroPCS
MetroPCS has officially introduced two new Android Gingerbread smartphones: the LG Connect 4G and the Samsung Galaxy Attain 4G. As their names suggest, both handsets feature LTE connectivity.
The LG Connect 4G is MetroPCS' first smartphone to have a 1.2GHz dual-core processor. It also comes with a 4 inch WVGA Nova display covered with Gorilla Glass, Wi-Fi, GPS, Dolby Mobile sound, pre-loaded Rhapsody Unlimited Music service, 5MP rear camera, 720p video recording, and a front-facing camera.
MetroPCS says the LG Connect 4G will be available next month (no word on its price).
As for the Samsung Galaxy Attain 4G, this is just an LTE version of the Samsung Conquer 4G (available at Sprint since last year). The handset features a 3.5 inch HVGA display, Wi-Fi, GPS, 1GHz single-core processor, 3.2MP rear camera, and a 1.3 MP front-facing camera.
MetroPCS will sell the Galaxy Attain 4G starting the coming weeks for $199.99.
Via Press release and Press release


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Halifax Health partners with Disney to improve patient satisfaction
Published: Monday, January 7, 2013 at 8:01 p.m.
Last Modified: Monday, January 7, 2013 at 8:19 p.m.
DAYTONA BEACH — When it comes to navigating health care reform's greater emphasis on pleasing patients, Halifax Health is turning to Mickey Mouse.
More than 4,000 employees will undergo four-hour sessions this month that stress the importance of service, quality standards, safety, compassion and efficiency.
Halifax Health partnered with the Disney Institute, the consulting arm of Walt Disney Co., to develop the program, which it is calling "The Cornerstone."
"We are looking forward to the outcomes," said Jeff Feasel, CEO of Halifax Health. "Part of this is to renew the culture here at Halifax Health and focus on our patients."
The Disney Institute works with companies in a variety of industries to improve customer service.
The health care law places a sharper focus on patient surveys, which will affect how much hospitals receive in future government payouts. The survey includes questions about the attentiveness of doctors and nurses and the cleanliness of the hospital.
Starting this fiscal year, the Centers for Medicare & Medicaid Services is withholding about $1 million from Halifax Health that can be earned back through following core standards of care, avoiding unnecessary readmissions and receiving favorable reviews from patients.
The idea is to reward hospitals that perform well and penalize institutions that do poorly.
The new rules are being phased in, and by the fiscal year 2017, more than $2.5 million will be at stake.
Rude employees could lead to poor survey responses, which is a main driver for why the hospital developed the program, said Ann Martorano, chief marketing officer.
"It's really the right thing to do no matter what, but obviously, it is important from a monetary standpoint because of health care reform," she said.
Not everyone is embracing the move to tie patient survey results to hospital funding. Critics argue that doctors might perform unneeded tests and procedures that could actually prove harmful in a drive to please patients.
"Medicine and customer satisfaction levels do not equal," said Daniel G. Francati, a member of the Halifax Health Board of Commissioners. "You may tell a patient that the best medicine is to lose weight, stop smoking, eat your vegetables and exercise. The patient doesn't want to hear that. He'd rather get a pill."
All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.
Comments are currently unavailable on this article


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huawei e1732 modem firmware update
the firmware update for huawei e 1732 is now available. as i posted the method to unlock huawei e 1732 using sola gsm calc, there were lots of comments on the post regarding troubles they had. so using this firmware update method you can easily unlock your e 1732 modem supplied here by idea. this update works on any huawei e 1732 modem. friends so enjoy your unlocked e 1732 without any hassle.
you can use this firmware update to unlock your huawei e1732. this will help you to use any sim in your huawei e 1732
so here is the step by step guide to unlock your huawei e 1732 by firmware update method.
download the huawei firmware updater for e1732 from here
huawei e1732 firmware updater free download
- open the rar file and run the application (password for rar file is 'freetrics'
- check the accept terms and condition radio button and click next
- wizard will now start to search the connected huawei e1732 modem
- click next to start updating
- at a point the updater asks for a password, here is the steps to generate the password for your huawei e 1732
- download huawei password generator from here
huawei flash code generator free download
- start application
- select the huawei tab in the top row
- enter iemi number of your huawei e 1732
- click generate to generate password for your huawei e1732 modem
- it will produce two codes use the "flash" code as your password
- download huawei password generator from here
- it will take few minutes to finish the update
it is very important that you keep your ups backup full. a power failure during the update may burn your huawei modem e 1732
if you have any problem doing this please dont forget to comment.
new way to unlock huawei e1732 permanently


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Justine Garcia
Top Flames Moment: UIC Volleyball Wins Five-Set Thriller at Cleveland State
UIC fought back from a 2-0 deficit to rally for a 3-2 victory
Top Flames Moment: UIC Volleyball Wins Five-Set Thriller at Cleveland State
UIC fought back from a 2-0 deficit to rally for a 3-2 victory
UIC Student-Athletes Go Through Commencement Services
35 student-athletes received a bachelor's degree in the spring and summer sessions
VIDEO HIGHLIGHTS: 2013 UIC Volleyball Senior Tribute
MaryKate Imrie (5-10, Setter, Orland Park, Ill.) and Justine Garcia (5-5, Defensive Specialist, Chicago, Ill.)
Flames Conclude Season with Four-Set Win Over Wright State
UIC falls one League win short of qualifying for the Horizon League Championship
UIC Volleyball vs. DePaul
UIC Volleyball vs. DePaul Sept. 25, 2013 DePaul 3, UIC 0
2013 UIC Invitational
2013 UIC Invitational (Sept. 6-7)
AS A SENIOR (2013): Saw action in 109 sets and led the team with 352 digs ... ranked ninth in the Horizon League with 3.23 digs per set ... 21 double-digit dig performances, including 11 straight from Sept. 14-Oct. 18 ... Finished with 1,036 career digs ... season-high 19 digs and four aces vs. Elon (Aug. 30) ... 18 digs at Kent State (Sept. 21), 17 at Cleveland State (Oct. 11) and 16 against both Drake (Sept. 13) and Wright State (Oct. 18) ... led UIC with 34 aces and .31 aces per set, ranking third in the Horizon League ... recorded four aces at Iowa (Sept. 14), claiming the League's second best four-set performance.
AS A JUNIOR (2012): One of the team's top defensive players ... she played in all 123 sets during the season ... earned the second-most digs on the team with 350 at 2.85 per set ... logged 21 over-10 dig performances ... collected five over-15 dig matches ... she now has five 20-plus dig performances in her career ... recorded a season-high 22 digs vs. Eastern Michigan on Sept. 1, 2012 ... led her team to a 3-1 victory over Wright State on Sept. 22, 2012 with 21 digs ... had three matches where she logged two service aces ... totaled 18 service aces during the season, the third-most on the team ... collected 17 digs during the 3-2 victory over Loyola during the quarterfinal round of the Horizon League Championship on Nov. 10, 2012 ... a recipient of the kinesiology Achievement Award ... one of three volleyball members named a Chancellor's Student Service and Leadership award winner ... selected as the team's U-I-C (Unity-Integrity-Commitment) Award winner at the team banquet.
AS A SOPHOMORE (2011): Logged 201digs on the season ... posted a season-high 21 digs against Montana State on Sept. 3, 2011 ... the 21-dig match marks her third 20-plus dig performance ... appeared in 93 sets ... ranked fifth on the team in digs ... averaged 2.16 digs per set ... academically, named to the "Bronze" Team, which is a grade-point average between 3.0-3.49.
AS A FRESHMAN (2010): Ranked fifth on team with 2.08 digs per set ... appeared in 64 sets ... collected her second 20-plus dig performance (21) at Saint Louis on Oct.9, 2012 ... tied a season-high with two aces at Saint Louis (10.9.10) ... collected a team-high 23 digs during her collegiate debut vs. DePaul on Aug. 27, 2010 ... earned the starting position as libero in her first college match vs. DePaul (8.27.10).
PREP AND PERSONAL: Three-time letterwinner at Gwendolyn Brooks College Preparatory Academy (Ill.) ... named the Eagles' MVP following her freshman campaign ... became the first player ever from Brooks to sign with an NCAA Division I program ... achieved High Honors in the classroom all four years ... born July 16, 1992, in Chicago, Ill. ... daughter of Jeff and Renee Garcia ... youngest of four children ... has three brothers, Jeff, Jason and Justin ... greatest athletic thrill to date is earning 23 digs against DePaul ... currently enrolled as a Exercise Science/Health Promotion major.
UIC Career-Highs


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Mercy Heart and Vascular Institute offers minimally invasive treatments for varicose veins in one convenient location - the Forest Park Medical Building, located on East Campus, 1000 Fourth Street SW, Mason City.
Visitors and patients of Mercy Heart and Vascular Institute – Vein Center also can take advantage of the free parking valet service on Mercy's East Campus.
Mercy Medical Staff have been treating venous reflux disease for more than 10 years and is now consolidated with the Mercy Heart and Vascular Institute to provide a more comprehensive approach in the diagnosis, treatment and management of vein disease.
About Varicose Veins
Symptoms caused by varicose veins include:
These symptoms can worsen as the day progresses.
Chronic venous disease of the legs is one of the most common conditions affecting people. Approximately half of the nation's population has venous disease - 50 to 55 percent of women and 40 to 45 percent of men.
Risk factors include:
As interventional radiologists, Ryan Holthaus, M.D. and Bryan Navaretti, M.D., and Vascular Medicine Director Ali Mardan, M.D., are trained in performing minimally invasive treatments - Ambulatory Phlebectomy and Saphenous Vein Ablation - using ulta sound imaging guidance. The procedures are very safe, effective and require almost no down time. All of our Vein Center physicians are board-certified.
Benefits of vein ablation treatment include:
Many insurance carriers cover the vein ablation treatment, based on medical necessity for symptom relief. Mercy Heart and Vascular Institute will help verify insurance coverage for potential patients.
Contact the Mercy Heart and Vascular Institute – Vein Center at 641-428-8001 to find out more information.


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How to find a function for calculating the number of well form brackets (for "n" pairs of brackets) using generating function? This is a probably a routine problem for some people, but I haven't got any resource on generating function.
Mathematics Stack Exchange is a question and answer site for people studying math at any level and professionals in related fields. It's 100% free, no registration required.
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If Hans Lundmark is right, you could see Wikipedia on the Catalan numbers, where the generating function is given under "Proof of the Formula" There are also many references in OEIS


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Calling all young emerging designer the LVMH Young Fashion Designer Prize contest is open until Feb 2. LVMH is home to some of the world's largest fashion brands such as Louis Vuitton, Emilo Pucci, Fendi, Givenchy and Marc Jacobs just to name a few.
In 2013 it announced the creation of a major prize for young designers with the prize of a grant of 300,000 euros and 12 months of personalized assistance from a special LVMH team in developing their company for a year after receipt of the LVMH Prize. This support covers all the areas of expertise that are critical to a young fashion brand (intellectual property, sourcing, production and distribution, image and advertising, marketing, etc.).
Here is some of the criteria for those interested in entry
- You are older than 18 and under 40
- You have produced at least two collections
- Your collections are menswear or womenswear (not accessories)
To apply go to http://www.lvmhprize.com/Subscription/Introduction/Type/Designer.sls
Here is the full process on how the winner will be chosen its a three-step selection process to reveal the winning young fashion designer.
To choose ten lucky finalists from among the thirty semi-finalists, forty international fashion insiders have been named. The finalists will present their collections to the final jury. Among the forty: Sarah Andelman, artistic director, Colette (Paris), Tim Blanks, editor at large, Style.com (London), Angelica Cheung, editor in chief, Vogue China (Beijing), Patrick Demarchelier, photographer (New York), Babeth Djian, editor in chief, Numéro (Paris), Lilian Pacce, fashion editor and writer (São Paulo), Sarah Mower, contributing editor, American Vogue (London), Tomoki Sukezane, stylist (Tokyo), Dasha Zukhova, editor in chief, Garage Magazine, and founder of Garage Museum of Contemporary Art (Moscow), and Natalie Massenet, founder and executive chairman of Net-a-Porter (London).
Step 1 : The LVMH Prize committee establishes a shortlist of 30 candidates.
Step 2 :The international committee of experts (comprising journalists, stylists and buyers) selects the ten finalists.
Step 3 : The jury, whose members are Creative Directors of the Group - Nicolas Ghesquière, Marc Jacobs, Karl Lagerfeld, Humberto Leon & Carol Lim, Phoebe Philo, Raf Simons, Ricardo Tisci - and Delphine Arnault, Jean-Paul Claverie, advisor to Bernard Arnault, and Pierre-Yves Roussel, Chairman and CEO of the LVMH Fashion Group chooses the winner of the LVMH Prize in May, 2014.


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Single Form Series 11 - Two Person Practice
Level: ADVANCED
Master Liao demonstrates major two-person practice forms such as: Hands Attaching, Single Hand Push, Both Hands Push, Roll Hands, Four Forms and Ta Lu (dah-lee). Each practice is performed on both right and left sides with instructions on how to move forward and backward, attach and separate. The video concludes with a discussion and demonstration of transferring power (Fa Jing) in eight major forms: Ward-Off, Roll-Back, Press, Push, Roll-Pull, Split, Lean Forward and Elbow.


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10:38, UK, Wednesday 28 May 2008
If your car is covered with a layer of sand or dirt today, it may have come all the way from the Sahara desert.
The UK does not normally receive airstreams coming from Africa - usually they travel in from the Atlantic - but winds today are blowing in from the desert region.
"As wind blows across the Sahara it carries off particles of sand - tonnes of it every day," said Sky News weather presenter Francis Wilson.
"The warm airstream carries the sand thousands of miles, and dust has already fallen over Spain and France.
"There could well be some Saharan dust mixed up in the rain that is going to fall in England and Wales.
"It's a pretty rare event - the dust reaches us only once or twice a year."
The Saharan dust itself is not responsible for the thunderstorms forecast for Britain today, but the hot air from Africa is what will provoke the torrential downpours.
Areas affected by heavy rain may experience localised flooding, the Met Office has warned.
But there is good news for later this week, when the Sun is expected to come out and temperatures are forecast to reach 22C in some parts of Britain.


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Dr. Sasha (Alex) Lessin
& Janet Kira Lessin
Answer Questions
from the More Loving Perspective
Lovers Sarcasm
Question: My girlfriend speaks sarcastically and mocks me with her voice and words. I hate it. She doesn't even realize she's being sarcastic. How can I
make her stop?
Sasha: Sarcasm veils anger but vents it indirectly.
We suggest you and your girlfriend discuss the hurt, fear or insecurity generating the sarcasm.
Next time she's sarcastic, tell her you feel hurt when she speaks that way.
Say, "I imagine speaking that way vents your anger. Under the anger, I'll bet you
feel scared, hurt or insecure, and I'd like to hear about that.
Tell me what you're angry about and I'll actively listen [Listen Actively
Cue Sheets] to you."
Kiss - Gustav Klimt
Set yourself to understand and empathize with her before you react.
Look in her eyes, keep your face neutral and make no reactive gestures or faces.
Every few sentences, ask her to stop, so you can see if you're getting her right.
Tell her what you heard her say and ask, "Is that what you're saying?" until she
agrees you accurately reflect her ideas.
Then say, "Is there more on this you'd like to say?"
When she's said all she chooses on the subject, summarize what she said
and say, "I imagine you felt...".
Then take your turn and respond to her concerns.
Alternate turns as speaker and listener till you work through the issue.
Tell your girlfriend that, from now on, when she's vexed with you, to use active listening instead of sarcasm.
Ask her, when she feels an impulse to be sarcastic, or when she or you notice she's becoming
sarcastic, to say, "I'm feeling (hurt, angry, disappointed).
I need you to listen actively to me; let's find a time so I can work through this feeling and feel close and loving again."
It may take a week or so of practice to get comfortable with this new way of sharing and it may take months for her to break her sarcasm habit.
Your girlfriend learned to communicate her anger through sarcasm long before she knew you, so be patient with her.


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Artist: David Sylvian
Album: Rain Tree Crow
Genre: Rock
David Sylvian
Rain Tree Crow
Black Crow Hits Shoe Shine City
The beat of his wings on the moon never tire
As black crow descends stealing somebody else's fire
Suffering is no cause for pity
As black crow hits shoe shine city
God's burned his wings
Struck dumb for his crimes
A black crow descends on shoe shine city
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text:
University of Cincinnati │College of Education, Criminal Justice, and Human Services
PO Box 210002 │Teachers/Dyer Hall │Cincinnati, Ohio 45221 │ 513-556-4307 | Help@CECH
Our Faculty & Staff
Robert E Harper
Title: Assistant Professor -
Educational Leadership Program
Office: 615 Teachers College
Tel: 513-556-2335
Email: email@example.com
Rob Harper graduated from the Urban Educational Leadership Doctoral Program at the University of Cincinnati in June 2008. His dissertation was titled, "The Professional Development Needs of Urban Principals in Ohio and Their Perceptions of Online Learning". He completed his Master's Degree in Educational Administration at the University of Cincinnati in 2005. Prior to pursuing his graduate level work, Rob was a music teacher for twelve years. His undergraduate work was completed in 1992 at the University of Cincinnati College-Conservatory of Music.
Currently, Rob is an Assistant Professor in the Educational Leadership Program at the University of Cincinnati. His research interests include online education, technology, school leadership preparation, and social justice education. View Curriculum Vitae (pdf)


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Egypt Tyrone Allen
Position: DB
Height: 6-0 Weight: 203 lbs.
Born: July 28, 1964 in Dallas, TX
High School: South Oak Cliff
College: TCU (school history) (Allen college stats)
Weighted Career AV (100-95-...): 2 (11632nd overall since 1950)
Other SR Links: College Football at Sports-Reference.com
Our primary support comes from users like you. Sponsor this page for $5. Your message will replace this ad.
Output includes all games from 1920 to 2015.


text:
Whether you are new to campus or returning for another year, moving into the Residence Halls is always a bit hectic. Be prepared by knowing when the dorms open, what to bring, where to park to unload, and more.
View and print move-in information >>
Ohio Dominican welcomes students to campus during Panther Welcome Weekend, August 14-16, 2015.
Resident students move in, commuters get to know each other, and we all have a fun weekend.
Residence Life Office
Erskine 145Ohio Dominican University1216 Sunbury RoadColumbus, Ohio 43219
Phone: (614) email@example.com


text:
Frank Pasquale
Frank Pasquale
Professor Pasquale joined Seton Hall after practicing law as an attorney at Arnold & Porter LLP, where his work included antitrust and intellectual property litigation. Professor Pasquale's prior experience includes clerking for the Honorable Judge Kermit Lipez of the United States Court of Appeals for the First Circuit and serving as a fellow at the Institute for the Defense of Competition and Protection of Intellectual Property in Lima, Peru.�
During his time at Yale Law School, Professor Pasquale served as a teaching assistant for first year students and as an editor of the Yale Law and Policy Review and the Yale Symposium on Law and Technology before graduating with a J.D. in 2001. He also served as a student director in the clinical program's Disabilities Clinic, focusing on advocacy in the health and benefits fields.
Scholarship & Teaching
Pasquale has focused his scholarship on enriching intellectual property and health law with insights from economics, philosophy, and social science. His work on search engines has been excerpted in Bellia, Post, & Berman's Cyberlaw and delivered to a plenary session of the Intellectual Property Scholars Conference. His work on retainer medicine was selected for presentation at the St. Louis University Health Law Scholars Workshop.
Pasquale teaches Administrative Law, Intellectual Property Law, Health Care Finance, and a seminar entitled Technology, Human Rights, and Equality. He also plans and participates in programs sponsored by the �law school's Gibbons Institute for Law, Science & Technology, and its nationally ranked �Health Law & Policy Program.� He is the Associate Director of the Gibbons Institute.
Outreach & Commentary
Professor Pasquale blogs at Concurring Opinions and Madisonian.net, and has has guest-blogged at Jurisdynamics.� At the Co-Op, his posts focus on methodology in legal scholarship, health law, and IP.� The Madisonian blog has a technology focus. Along with Gaia Bernstein and Jim Chen, Pasquale organized a virtual symposium at Law & Technology Theory.
Pasquale has been quoted in the New York Times, San Francisco Chronicle, Los Angeles Times, and many other publications.� He has appeared on CNN to comment on Google's China policy. He has been interviewed on search engine regulation on David Levine's Hearsay Culture podcast (Jan. 24, 2007) and on National Public Radio's Talk of the Nation.
- State of the Net Conference West 2008 August 6, 2008
Biography last updated July 28, 2008


text:
VFE Pedals White Horse Optical Compressor
Regular Price: $199.00
Special Price: $149.25Combining ultra-premium components, soft touch true bypass, built in overdrive, and a clean blend, the VFE White Horse Optical Compressor will leave your tone alone, or completely transform it depending on how you set it. Learn More
VFE Pedals The Scream Overdrive
Regular Price: $199.00
Special Price: $149.25The Scream from VFE Pedals is a total remake of the classic TS circuit. Designed to give the original tone with more control and options, the Scream from VFE Pedals will please the classic TS lovers as well as the guitarists that need more versatility from their tone. Learn More
VFE Pedals Dark Horse Hard Edge Distortion
Regular Price: $199.00
Special Price: $149.25If you're looking for a distortion pedal that truly runs the gamut from light blues breakup to all-out distorted war, look no further than the VFE Dark Horse. Like its name implies, the Dark Horse is an unexpected box to win it all. Learn More


text:
Select Folder - From Api
This Article Covers
Domino Resources - Part 7
Download this strategic guide on moving Exchange Server transaction logs
Brush up on how log files have changed in Exchange to protect your setup against disaster, discover how to effectively purge transaction logs, and learn how to free up some of the disk space transaction logs have taken up on your drive.
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FOLDER to save files? Well, this piece of code can do that for you. I've put
this and a lot of others functions API functions in a script library, i don't
need to tell you why...
Put the first part in Declarations Section, and the rest as a function, that
returns the path selected. It's perfect when you need to select ONLY A FOLDER,
and not a file.
Have fun...
Type BROWSEINFO
hOwner As Long
pidlRoot As Long
pszDisplayName As String
lpszTitle As String
ulFlags As Long
lpfn As Long
lParam As Long
iImage As Long
End Type
Declare Function SHGetPathFromIDList Lib "shell32.dll" Alias
"SHGetPathFromIDListA" (Byval pidl As Long, Byval pszPath As String) As Long
Declare Function SHBrowseForFolder Lib "shell32.dll" Alias "SHBrowseForFolderA"
(lpBrowseInfo As BROWSEINFO) As Long
Function BrowseFolder (path As String, windowtitle As String) As String
Dim X As Long, bi As BROWSEINFO, dwIList As Long
Dim wPos As Integer
Dim cam2 As String
bi.pszDisplayName = path
bi.hOwner = hWndAccessApp
bi.lpszTitle = title
bi.ulFlags = BIF_RETURNONLYFSDIRS
dwIList = SHBrowseForFolder (bi)
cam2 = Space$(512)
X = SHGetPathFromIDList(Byval dwIList, Byval cam2)
If X Then
wPos = Instr (cam2, Chr(0))
BrowseFolder = Left$ (cam2, wPos - 1)
BrowseFolder = ""
End If
End Function
Sub Click (Source As Button)
Dim session As New notessession
Dim wk As New notesuiworkspace
Dim uidoc As NotesUIDocument
Dim doc As NotesDocument
Dim folder As String
Set uidoc = wk.CurrentDocument
Set doc = uidoc.Document
folder = BrowseFolder (doc.CERT_Destination(0), "Choose the folder to save
ID File:")
If folder <> "" Then
Call uidoc.FieldSetText ("CERT_Destination", folder + "\")
Call session.SetEnvironmentVar ("CERT_Destination", folder + "\")
End If
End Sub


text:
Coach Gimmillaro enters his 30th season as Head Coach.
July 29, 2014
LONG BEACH, Calif. – Season tickets for the 2014 Long Beach State women's volleyball campaign are now on sale. Season ticket packages for every match at the Walter Pyramid this season start at $110, which is less than $7 per home match. Courtside season tickets are also available for the first time ever for just $165 and a $100 donation per seat to the Beach Athletic Club's scholarship fund.
To order, call the Pyramid Ticket Office at (562)985-4949 or purchase online.
With 16 of its 30 matches at home this season and All-Big West first team selection Chisom Okpala back at middle blocker, The Beach is poised for another strong season. The 2014 season will be a special one as Brian Gimmillaro leads the 49ers for his 30th season.
This year's home schedule will feature two home tournaments and eight Big West home matches. The two home tournaments are the Long Beach State Mizuno Invitational and the LBSU/LMU Tournament with each featuring four home matches for LBSU.
Season tickets also guarantee a seat at all of the premier home matches in Big West play. Perennial power Hawai'i visits the Pyramid on Oct. 11 while reigning Big West co-champions CSUN and UC Santa Barabra visit on Oct. 3 and Nov. 15, respectively. The season will wrap up with two heated rivalry matches as UC Irvine and Cal State Fullerton visit on Nov. 28 and 29.
Single game tickets will go on sale on August 11. For more information, please call the Walter Pyramid Ticket Office at (562)985-4949 or visit the TIcket Office online by clicking here.
Sport Links
- Camp Information
- 49er Volleyball Camp
- 49er Camp Flyer
- 49er Women's Volleyball
- Roster
- Weekly Release
- Overall Statistics
- 2015 Quick Facts
- Ticket Information
- Walter Pyramid
- Recruits and Program
- Recruiting Information
- Head Coach Brian Gimmillaro on Straight Talk (Video)
- 2012 Fundraising Dinner
- Related Links
- Volleyball Magazine
- USA Volleyball
- RichKern.com
Media Guides
Section 1Team Information and Opponents
Section 2Long Beach State Record Book
Section 3This Is Long Beach State
Section 4Complete Media Guide
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Big West champion and undefeated Long Beach State swept the top awards from the Big West...


text:
Educators from around southeastern Michigan eagerly marched into Wayne State University's School of Education building, at 8 a.m. Saturday, May 3, to be part of the 4th Annual EdCampDetroit's Unconference. So what's an "Unconference?"
In the best interest of the new student centered education, a new paradigm shift where students have more say in the parts of their discipline they best like to study, the Unconference allowed educators to simply choose what they wanted to present and to whom and what they wished to visit. The process began with a bit of a friendly frenzy as dozens of enthusiastic K-12 and higher education teachers, administrators, and staff, signed up for numerous white board time slots.
After an hour of mingling, coffee, and donuts, the race was on to get settled into the first presentation offerings scattered throughout the basement and first floor. From Using Social Networks for Common Core Writing < my offering, to the Power of Augmented Reality in Education by Drew Minock and Erin Klein, to Using Wonderopolis.org by Nick Lawrence and Jennifer Vivian to Nurturing the Passions of Your Students by Jennifer Bond, the scope of topics all things education, particularly incorporating technology and the Common Core, had everyone wishing they could concurrently visit every session! And for those who simply wanted to understand how to digitally best connect with teachers, Todd Bloch explained the how and whys of #MichED.net.
Sessions ran from 9:30 to 3:30 with an hour lunch break. Planning is already underway for 2015 and "participant driven" organizers: Nick Provenzano, Chris Fritz, Karen Chichester, Mike Kaechele, Melanie Gray, Erin Klein, Cheryl Lykowski, Jennifer Bond, Bethany Beaudrie, Dan Spencer, and Linda Clinton plan to do more publicity and expect more educators to take advantage of the free day. Tickets were available on a first registration basis at EventBright. This was a fabulous event with enormous potential and the networking was priceless.


text:
The Plan
Building Tumaini Academy The plan for the school was developed by the Christian community in Sololo, Kenya with consultation and funding from KCEP in the United States. The Academy was named 'Tumaini'—the Kiswahili word for 'Hope'—because it will give the people of Sololo hope for a brighter future and will help them to know God hears and answers the prayers of His people.
Tumaini does not accept government money so that Christian faith may be expressed in the classroom. Of course, children of all faiths are welcome to attend Tumaini as we seek to provide quality education and hope to the people of Sololo.
Our Dream Our dream is to build new classrooms each year and add to the facility until the school is complete. We will enroll approximately 40 students per grade, bringing the total student body to over 360 children. We are committed to helping construct the necessary school buildings and hiring teachers until we bring quality education to needy students from kindergarten through Primary-seven (7th Grade). If we stay on schedule, we will complete all classrooms by the end of 2015.
A few miles from Sololo in the predominately Christian village of Anona, impoverished children are attending a nursery school in the local dilapidated church building. Tumaini school leadership decided to officially bring in Anona as another nursery school from which children may attend their primary school. Our priority in this partnership is to build a new nursery classroom for these children as we join hands with this neighboring community.
KCEP's dream is to extend our partnership to include other Northern Kenyan communities as well. It would be possible with just ten schools to serve as many as 3,000 children! As financial resources become available, we hope to be able to provide quality faith-based education and extend our influence over a larger geographic area.
To help the poorest of the poor receive this excellent private Christian education, our plan has always been to offer a sponsorship program under the direction of the Anglican Bishop of Northern Kenya and his staff so that children can attend Tumaini Academy regardless of their financial means.
From Dream to Reality The dream is becoming a reality! In December, 2010 construction began on the Nursery/Kindergarten and Primary-One classrooms. On January 10th, 2011, Tumaini opened its doors for the first time, welcoming approximately seventy children in their new uniforms to each classroom and two highly qualified teachers employed from the southern part of Kenya. Since 2011 Tumaini added primary 2 and 3 classroomsand in this year and half, Tumaini has grown to over 200 students!
Financial Support Our ambitious fundraising goal set forth in the fall of 2010 was exceeded and we were able to meet all construction goals! In 2011 we continued our building progress and all financial needs were met thanks to our generous donors!
For 2012 we have set the goal to build a Primary 4 classroom and the Anona nursery classroom to meet the needs of a growing school. The fundraising goal for each classroom is $8,000.


text:
PR # 182 March 19, 2009
Raritan Valley Community College will present a student/staff performance of Eve Ensler?s The Vagina Monologues , Tuesday, April 21, at 7 p.m. The presentation will be held in the Welpe Theatre at the College?s North Branch Campus.
Proceeds from the performance, which is part of the College?s celebration of Women?s History Month, will benefit the Resource Center for Women and Their Families.
The RVCC production will be repeated Tuesday, April 28, at 8 p.m., at the Somerset Valley Playhouse, 689 Amwell Rd., Hillsborough.
The Vagina Monologues is based on playwright Ensler?s personal interviews with more than 200 women about their memories and experiences of sexuality. With humor and grace, the piece celebrates women?s sexuality and strength and gives voice to experiences and feelings not previously exposed in public. The award-winning play has been produced in thousands of colleges, universities, cities, towns and high schools since 1998, with unrivaled success. The Vagina Monologues also has inspired a dynamic grassroots movement across the country?V-Day?to stop violence against women. These events have been responsible for raising millions of dollars for local charities.
The RVCC production is being directed by Jessica Zorn, with assistant directing by Lindsay Zorn. The cast includes: Cassy Kalley, Megan Oates, Kristin Lobby, Sandy Behre, Brionna Castillo, Cassie Clark, Rachel Ignatoff, Kellianne Buschinski, Jenna Meyer, Heather Mussel, Nicky Singer, Krista Sharlin, Carina Metz, Amanda Kohlhepp, Melissa Karnilaw, Ashley Layton, Nicolette Klinger, Margaret Ervin-Willis and Mary Sullivan.
The production is sponsored by RVCC?s Social Justice Club and the Resource Center for Women and Their Families. Tickets cost $10 for students/seniors, $15 for general admission. For information, call the Resource Center for Women and Their Families, 908-359-0003, ext. 220, 9 a.m. to 3 p.m. daily. Visa, MasterCard and American Express are accepted.
RVCC, located on Route 28 and Lamington Road in North Branch, NJ, and serving Somerset and Hunterdon County residents for 40 years, offers more than 90 associate degrees and certificates. For further information, visit www.raritanval.edu .
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text:
Fareed Haque
« Back
Guitar virtuoso Fareed Haque enjoys a career that spans the spectrum of musical styles. Born in 1963 to a Pakistani father and Chilean mother, extensive travels exposed Haque to a variety of music from an early age. This natural eclecticism has become the hallmark of his music. He has performed all of the major guitar concertos, is an active transcriber of baroque, as well as South American music. He has had numerous modern works dedicated to him.
Moving easily between jazz and classical guitar, Haque's versatility has created a demand for him with prominent jazz and classical artists including members of the Vermeer Quartet and many symphony orchestras in the U.S. and abroad. He has also released five recordings as a leader: Voices Rising, Manresa, Sacred Addiction, Opaque, Déjà vu and Singh Song. He has been featured on WTTW's ArtBeat, Ben Sidran's New Visions, Michelob Presents Sunday Night on NBC, his own Lonesome Pines Special for PBS and on BET cable jazz channel. He has twice been selected Talent Deserving Wider Recognition in Down Beat magazine.
In 2001, Haque co-founded the jam super-group Garaj Mahal and joined George Brooks group Summit featuring Zakir Hussein and Steve Smith. He continues to record and tour with the Fareed Haque Group. Most recently he became a staple of the Jamband scene and was voted Most Valuable Player at the 2002 High Sierra Music Festival. He currently is an associate professor in jazz and classical guitar studies at Northern Illinois University.


text:
These sure look delicious. I've never seen them for sale around here.
I wonder if it actually contains any cactus in the candy?
Interesting. And it's in the shape of a cactus.
You can also bookmark this on del.icio.us or check the cosmos
RSS feed for comments on this post. | TrackBack URI
3 Responses
satsumabug Says:
November 29th, 2009 at 3:56 pm
When I was a kid, my aunt used to bring me cactus candy when she went on business trips to Arizona. I always have been a sucker for any kind of gummy sugar-coated fruit candy, and I loved those!! I think they were made from prickly pear juice.
Cactus Says:
November 29th, 2009 at 5:45 pm
They sound delicious. I want some!
Christine Says:
December 1st, 2009 at 5:21 pm
What about Lakerol's cactus flavor? They're popular in Scandinavia. Here's a link to a poster: http://www.advertolog.com/lakerol/print-outdoor/cactus-331601/


text:
Here are a few of the items we are currently stocking in the store. Come by and browse.
War Eagle!!
We custom make appliques! Prices start at $20.00 for tshirts, $22.00 for long sleeve ts, $27.00 for sweatshirts, and $32.00 for hoodies. We use Vera Bradley patterns for the most part, but have other patterns available, or bring in your favorite.


text:
Feb 21, 2012 10:20 AM
We travel once a month to go visit our long-distance boyfriend Down South. It's tough but it is definitely worth it, especially when he cooks all weekend and offers to bring breakfast in bed on Sundays. Because we go so often, we've got our packing routine down to a science. We wear a pair of jeans, pack a nice blouse, two dresses, and a cardigan, toss in some panties, and layer our well-organized travel jewelry and toiletries on top. Eve Lom Travel Essentials ($95) has a permanent place in that luggage puzzle. We can't do without their Morning Time Cleanser and Rescue Mask. We like to be as fresh as the Sunday morning orange juice that is waiting on our bedside table.
If you've got a product or service that you'd like to promote on Outblush, click here to find out about our advertising opportunities.
Outblush is a blog for girls who love to shop. Our staff digs up the best clothes, home stuff, beauty items, and more. New items are posted every day — bookmark us and check out:


text:
Romney joins rival Gingrich in the viper pit, and it's working
Charles Dharapak, Associated Press
» View our political blog, with live updates and analysis of the GOP presidential nomination process.
NAPLES, Fla. — The increasingly negative tone of the GOP presidential primary race here comes as no surprise to Mitt Romney supporter Paul Juster.
"If you're going to get in the ring with the big boys, you've got to be just as bad. If you're in a viper pit, you've got to be a viper," said Juster, who retired to Florida from Massachusetts, where Romney served as governor.
Romney is on the attack and key supporters from Utah are playing a role in helping him take on chief rival Newt Gingrich. With the election only days away, polls show the strategy appears to be working.
Juster said he's trying to ignore the bitter back-and-forth between Romney and Gingrich. "They can shoot each other in the foot all they want," he said. Still, he said it may be what's needed against an opponent like Gingrich, who won the South Carolina primary after hammering Romney on the business dealings that earned him millions.
The loss taught Romney a lesson, Juster said. "It's a shame that it has to be this way."
Rep. Jason Chaffetz, R-Utah, who is campaigning for Romney in Florida, said voters need to hear the tougher talk.
"I think people want him to be more proactive," Chaffetz told the Deseret News. "I think that was one of the challenges in South Carolina."
The newly aggressive Romney campaign is to show he can "take the fight to Barack Obama. That was the concern I heard from people, does he have the fight in his belly. This demonstrates he does," Chaffetz said.
Chaffetz, who first hit the campaign trail for Romney in Iowa, is attending Gingrich campaign events as a Romney surrogate, offering the media an immediate response to any statements made by the former Speaker of the U.S. House of Representatives.
Other Utah political figures helping Romney include former Gov. Mike Leavitt.
"I'm pitching in wherever I can," Leavitt said before leaving Florida on Sunday. "Romney supporters have reason to feel optimistic, but there is little certainty, and all systems are at full throttle."
Frank Ball, another retiree in Naples, said he understands the need for Romney to go on the attack.
"I'd be happier if it wasn't taking place," Ball, a Romney supporter, said. "But I don't think anyone can stand by if the guy is doing that. South Carolina proved that."
Naples resident Stacy Fields said she's not bothered by the negative ads from both Romney and Gingrich that are blanketing the airwaves.
Nor is she concerned when the candidates criticize each other on the campaign trail.
She said she had considered voting for Gingrich. "I liked his toughness, but I just feel Romney would make a better president," Fields said. "But he could be tougher."
The new edge was evident Sunday, when Romney compared Gingrich to Goldilocks, the fairy-tale character who finds fault with everything during a speech to a crowd of some 1,000 mostly retirees gathered at a Naples shopping and entertainment complex.
Romney, who is leading in several polls by more than 10 percentage points over Gingrich, reminded the crowd of his debate performance earlier this week, where he was uncharacteristically aggressive, calling it "a hoot."
He said it may be time for Gingrich "to look in the mirror" rather than make excuses for his slide in support and then slammed the former speaker for "selling influence in Washington."
Later, Romney flaunted his new feistiness when hecklers tried to interrupt a speech outside a restaurant in largely Hispanic Hialeah, near Miami.
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text:
Hardin-Simmons women's basketball head coach Melanie Chonko gives Lindsay Cash a mid-season report on her 3-5 squad.
HSU Women's Basketball Coach Melanie Chonko gives mid-season report
Published On: Dec 29 2013 02:18:54 PM CST
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The views expressed are not those of this site, this station or its affiliated companies. By posting your comments you agree to accept our terms of use, which are located at the bottom of this page.


text:
Dr. Lynn Butterly Honored by American Cancer Society for Colon Cancer Prevention Efforts
November 30, 2007
The American Cancer Society's annual awards celebration, held Thursday, November 15 in Concord, honored New Hampshire volunteers who have spent the past year making a difference in the fight against cancer. Lynn Butterly, MD, Director of Colorectal Cancer Screening for Dartmouth-Hitchcock, was presented with the Singer Family Award for her outstanding achievements in furthering the mission of the American Cancer Society in New Hampshire.
Dr. Butterly first began volunteering for the American Cancer Society seven years ago with a project to educate primary care providers on the need for colon cancer screening. She also conceived and designed the New Hampshire Colorectal Cancer Screening Community Outreach Project, and led a group of volunteers traveling to underserved areas of the state performing screening fairs. In no small measure due to her efforts, the colon cancer screening rate in New Hampshire has risen from 46% to 64% over that seven year time frame.
Dr. Butterly is currently Chairperson of the New Hampshire Comprehensive Cancer Collaboration, a position she has held since the group's inception. In this role, she has been instrumental in the development, implementation, and funding of the cancer plan for New Hampshire, which will lead to fewer cases of cancer, fewer deaths, and improved quality of life for all New Hampshire residents.
Dr. Butterly has served as a highly effective colon cancer spokesperson to both the general public and to her fellow health care professionals. She has volunteered her time to conduct Continuing Medical Education lectures throughout the state, including in our rural, underserved areas, to audiences totaling hundreds of health care providers.
Mark A. Israel, MD, director of Norris Cotton Cancer Center said, "We are deeply appreciative of Dr. Butterly's tireless efforts to improve cancer prevention and care in New Hampshire, particularly through her work on the State Cancer Plan. We are pleased that the American Cancer Society has recognized these efforts by awarding her the Singer Family Award."
The Singer Family Award, named in honor of one of the Society's longtime benefactors, was instituted in 1993 to recognize those who demonstrate an exceptional level of commitment to furthering the mission of the American Cancer Society.


text:
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Sennepin, Alexisa,b,c; Baychelier, Florencea,b; Guihot, Amélied; Nel, Isabelled; Fang, Raphaël Ho Tsongc; Calin, Ruxandrae; Katlama, Christinee; Simon, Annef; Crouzet, Joëlc; Debré, Patricea,b,d; Vieillard, Vincenta,b
aINSERM UMR-S 945, Hôpital Pitié-Salpêtrière Paris
bUniversité Pierre et Marie Curie (Paris-6)
cInnaVirVax SA, Evry
dAP-HP, Département d'Immunologie Hôpital La Pitié-Salpêtrière, Paris
eAP-HP, Service des Maladies Infectieuses, Hôpital La Pitié-Salpêtrière
fAP-HP, Service de Médecine Interne. Hôpital La Pitié-Salpêtrière Paris, France.
Correspondence to Vincent Vieillard, PhD, Laboratoire Immunité and Infection, Université, Pierre and Marie Curie, INSERM UMR-S 945, Hôpital Pitié-Salpêtrière, 83 boulevard de l'Hôpital, Bâtiment CERVI, 75013 Paris, France. Tel: +33 1 42 17 75 24; fax: +33 1 42 17 74 90; e-mail: email@example.com
Received 7 January, 2013
Revised 21 March, 2013
Accepted 27 March, 2013
This work was supported in part by the Institut National de la Recherche Médicale (INSERM), and the Université Pierre et Marie Curie, Paris. Alexis Sennepin is supported by a CIFRE fellowship from the Association Nationale de la Recherche et de la Technologie (ANRT) and InnaVirVax SA (#846/2009)
Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Website (http://www.AIDSonline.com).
Objective: HIV-infected immunological nonresponders (InRs) patients fail to show satisfactory CD4+ T-cell recovery despite virologically effective HAART. We propose that NKp44L, the cellular ligand of an activating natural killer (NK) receptor, expressed only on uninfected bystander CD4+ T cells from HIV-1 infected patients, could play a major role in this phenomenon by sensitizing these cells to NK killing.
Design: Phenotype and multifunctional status of CD4+ T cells, especially the subsets expressing and not expressing NKp44L, were characterized for HIV-infected patients receiving HAART for at least 2 years, during which their viral load remained less than 40 copies/ml; 53 were InRs (CD4 cell count always <350 cells/μl), and 82 immunological responders (CD4 cell count always ≥350 cells/μl). Flow cytometry determined NKp44L expression in association with specific markers of proliferation, maturation, activation, homeostasis, and intracellular cytokine production. Degranulation of NKp44+ determined the functional capacity of NK cells.
Results: InRs exhibited high levels of NKp44L+CD4+ T cells. Compared with NKp44L negative cells, the frequency of naive CD45RA+CCR7+ T cells expressing NKp44L fell (P < 0.001) and their proliferative capacity grew. Moreover, apoptosis and a unique ability to produce multiple cytokines (IL-2, IFN-γ, and TNF-α) without or after phytohemagglutinin or anti-CD3/CD28 stimulation distinguished NKp44L+ T cells.
Conclusion: InR status is associated to a significant expansion of highly differentiated, multifunctional and apoptotic CD4+ T cells expressing NKp44L. This could explain a rapid CD4+ T-cell turnover in InR preventing immune recovery. These data suggest a new target for developing therapeutic strategies to prevent NKp44L expression and then stimulating immune recovery in InRs.
Although HAART induces immune reconstitution in most patients, up to 30% of HIV-infected patients receiving long-term HAART show no marked increase in their CD4+ T-cell count, despite complete suppression of their plasma HIV load. These patients are referred to as discordant or immunological nonresponders (InRs) [1–3]. Their impaired immunological recovery has been associated with variables including older age, therapeutic failure, poor adherence, genetic and virological characteristics, hepatitis co-infection, and low nadir CD4+ T-cell counts. This discordant response is often accompanied by a worse outcome and a faster clinical evolution than seen in full immunological responders [2–6]. In clinical terms, normalization of CD4+ T-cell count and function is a pivotal target in managing HIV infection, as the likelihood of developing non-AIDS comorbidities, including cardiovascular and renal diseases and cancers, is associated with the duration of CD4 cell counts below 500 cells/μl [7].
Despite intensive investigation, the mechanisms explaining this phenomenon remain largely unknown, although low production of new T cells, due to bone marrow or thymus impairment, and increased CD4+ T-cell destruction, revealed by high sensitivity to cell death ex vivo, contribute to InR status [8]. The unbalanced T-cell homeostasis may also be influenced by undetectable, ongoing viral replication, especially in the tissues. Other suggested causes include microbial translocation from the gastrointestinal lumen and adverse effects of antiretroviral drugs at the mitochondrial level [9]. Alternatively, failure of CD4+ reconstitution could be also explained by a CD4+ T-cell sequestration in lymph nodes, or by the potential dysregulation of inflammatory cytokines such IFN-α and IL-6, as well as IL-7 in T-cell homeostasis [10,11].
The CD4+ T-cell loss observed during the chronic phase of infection initially results from the death of productively infected CD4+ T cells, through the cytopathic effects of viral replication and CD8+ cytotoxic T lymphocyte (CTL)-mediated killing [12]. Several studies have demonstrated, however, that most dying cells are uninfected and thus suggest that the death of uninfected bystander CD4+ T cells plays a major role in CD4+-cell depletion [13]. Numerous studies have strengthened this hypothesis; they imply that several HIV-1 proteins, including gp120, Tat, and Nef, activate several disparate pathways to initiate apoptosis in uninfected cells [14]. An alternative proposal is that the high level of immune activation in HIV-infected individuals causes the death of uninfected CD4+ T cells [15]. We have suggested that NKp44L, the ligand of an activating NK receptor that is only expressed on uninfected bystander CD4+ T cells from HIV-1-infected patients, may play a major role in this phenomenon, rendering these cells sensitive to NK killing [16–19]. This mechanism has been thoroughly investigated at the cellular level and the pathway leading to NKp44L expression at the surface of human CD4+ T cells has been deciphered [20]. Experiments in a model of simian-human immunodeficiency virus (SHIV)-infected macaques indicated that in-vivo inhibition of NKp44L expression correlates with prevention of CD4+-cell depletion and emphasized the ligand's critical role [21,22].
In view of the prognostic and functional role of NKp44L and in an attempt to shed light on the lack of CD4+ T-cell recovery during virologically successful HAART, we have characterized the phenotype and multifunctional features of CD4+ T cells in relation to their NKp44L expression in a well characterized cohort of InRs and compared them with those among full immunological responders and healthy donors. Our results lead us to propose a new phenomenon to explain the lack of CD4+ cells recovery in InRs linked to the persistence of NKp44L.
Table 1 summarizes the characteristics of the HIV-infected patients included in this study: 53 InRs and 82 immunological responders at the Pitié-Salpêtrière Hospital, Paris, France.
All recruited HIV-infected patients had been receiving HAART for at least 2 years and had undetectable viral loads (plasma HIV RNA copies <40 per ml). InRs were defined by a CD4+ cell count that remained below 350 cells/μl during the past 2 years, although the immunological responders had CD4+ cell count of 350 cells/μl or above throughout this period. These patients were negative for other infections. The hospital blood center (Etablissement Français du Sang) provided blood samples from 72 anonymous healthy donors as controls. All works were conducted in accordance with the Declaration of Helsinki. All patients provided written informed consent, and the relevant institutional review board (Pitié-Salpêtrière Hospital, Paris, France) approved the study.
CD4+ T cells were analyzed from the peripheral blood. Fresh cells were first incubated with 2 μg/ml of anti-NKp44L mAb (#7.1) [12] for 45 min at room temperature, washed in PBS/BSA 0.5%, and then stained with a 1/50 dilution of rat antimouse IgM-PE (Becton Dickinson) for 30 min [19]. Cells were next labeled with an appropriate combination of antibodies: CD4-FITC or CD4-APC, CD127-FITC, HLA-DR-PeCy7, PD1-PeCy7, CCR7-PeCy7, CD38-APC, CD95-APC from Becton Dickinson), CD45RA-Texas Red (Invitrogen), and CD3-FITC or CD3-ECD (Beckman Coulter). After staining, FACS Lysing Solution (Becton Dickinson) was used to lyse erythrocytes. Acquisition was performed on a Gallios flow cytometer (Beckman Coulter) and analyzed with Kaluza Software.
NKp44L-PE, CD3-ECD, and CD4-APC mAbs were used to stain 5 × 105 PBMCs that were then incubated with annexin V-FITC (Becton Dickinson) for 15 min, according to the manufacturer's recommendations. Cells were analyzed by flow cytometry in the CD3+CD4+ lymphocyte gate.
NKp44L-PE, CD3-ECD, and CD4-APC mAbs were used to stain 5 × 105 PBMCs that were then fixed and permeabilized with the FoxP3 kit (e-biosciences). After washing, cells were stained for Ki67-PECy7 (Becton Dickinson) mAb and washed in PBS before flow cytometry on the CD3+CD4+ lymphocyte gate.
Degranulation of NK cells was performed according to a method previously described [23]. Briefly, freshly isolated nonactivated PBMCs (5 × 105) were resuspended in the presence of anti-CD107a-FITC mAb (H4A3; Beckton Dickinson). After 1 h of incubation, monensin (Sigma–Aldrich) was added at 6 μg/ml for an additional 3 h of incubation before staining with CD3, CD56 and NKp44 mAbs, followed by flow cytometry analysis on the CD3−CD56+ NK-cells gate.
Freshly isolated PBMCs (5 × 105) were or were not stimulated with 4 μg/ml of phytohemagglutinin (PHA-P) (Oxoid) or 6 μg/ml of anti-CD3 (UCHT-1) and 6 μg/ml of CD28 (CD28.2) (Beckman Coulter) antibodies for 5 h at 37°C in the presence of Golgi Stop and Golgi Plug solutions (Becton Dickinson). Cells were then stained for cell-surface markers (NKp44L, CD3, and CD4), fixed (BD Cell Fix, Becton Dickinson), permeabilized with Cytofix/Cytoperm reagent (Becton Dickinson), and stained for intracellular IL-2 (PE-Cy7; MQ1–17H12; Becton Dickinson), IFN-γ (Alexa-Fluor-700; B27; Becton Dickinson), and TNF-α (APC; Mab11; E-Biosciences) expression. Data were analyzed with Flow Jo version 9 (TreeStar, Ashland, Oregon, USA), and the rate of CD4+ T cells positive for 0, 1, 2, or 3 functions was defined with the software's Boolean gate algorithm. Pestle software was used to remove the background. Pie charts generated by Spice software (NIAI freeware) present the frequency of CD4+ T cells positive for 0, 1, 2, or 3 responses (to IL-2, IFN-γ, and TNF-α), while arcs depict the frequency of cells specifically positive for each of these cytokines, as previously described [24].
All statistical analyses were performed with Prism 5 software (GraphPad, San Diego, California, USA). Nonparametric Wilcoxon and Mann–Whitney tests were performed to compare paired data and two independent groups, respectively. The Kruskal–Wallis test with the Dunn post-test for P-value calculation was used for multiple comparisons of independent groups. P-values < 0.05 were considered significant. *P < 0.05; **P < 0.01; ***P < 0.001.
The study included 135 HIV-infected patients with undetectable plasma viral levels (<40 copies/ml): 53 InRs and 82 immunological responders (Table 1). These groups were also compared with the group of 72 healthy donors. The two groups of HIV-infected individuals did not differ significantly for sex, age, or history of AIDS-defining conditions (Table 1). In contrast, at analysis, they differed markedly for their CD4/CD8 ratios and for both the proportion of CD4+ cells and the absolute CD4+ T-cell count. Their median CD4+ T-cell counts differed significantly (P < 0.0001): 253 ± 55 cells/μl for the InRs and 547 ± 122 cells/μl for the immunological responders (Fig. 1a). A significant difference was also observed in their frequency of CD4+ T cells (P < 0.0001) (Fig. 1a).
We have previously shown that NKp44L is expressed on CD4+ T cells during HIV-1 infection and is correlated with their progressive depletion [16]. In line with these data, Fig. 1b shows that NKp44L was expressed in InRs significantly more often (33 ± 23%), than in immunological responders (P < 0.0001) or healthy control individuals (P < 0.0001), both with levels close to background (Fig. 1b and c). Consistently, NKp44L is mainly expressed in CD4+ T cells with CD4 cell count below 350 cells/μl (Fig. 1d). We also assessed the frequency of CD3−CD56+ NK cells and observed similar levels in each subset of individuals (data not shown). However, NK cells from some InRs harbored NKp44, the specific NK cytotoxic receptor of NKp44L, which is only observed on activated cells [25]. Thus, NKp44 was present at the surface of a significant fraction of NK cells from InRs, but not on NK cells from immunological responders or healthy donors (Fig. 1e and f). More importantly, we next assessed the degranulation capacities of NK cells in the whole PBMC, and shown that the frequency of CD107a is significantly higher in InRs, compared with healthy control and immunological responders, in accordance to the frequency of NKp44 expression on NK cells (Fig. 1g and h). Altogether, these data are in line with the sensitivity of NKp44L+CD4+ T cells for activated NKp44+ NK killing [16].
To characterize CD4+ T cells expressing NKp44L more fully in InRs, we first assessed peripheral CD4+ T-cell maturation positive or negative for NKp44L. Figure 2a shows that the frequency of CD4+ naive CD45RA+CCR7+ T cells (CD4+ TN) was significantly lower, and the frequency of CD4+ effector memory CD45RA−CCR7− T cells (CD4+ TEM) higher in NKp44L+, compared with NKp44L negative cells, Thus, CD4+ TN accounted for 12 ± 9% of NKp44L+ cells and 26 ± 13% of the negative subset (P < 0.001) in the InRs, whereas CD4+ TEM accounted for 45 ± 15% and 34 ± 16%, respectively (P < 0.05) (Fig. 2a). Note that in the InR group, these two subsets (NKp44L positive and negative) did not differ for the frequency of CD45RA−CCR7+ central memory CD4+ T cells (CD4+ TCM).
In line with these data, CD38, which is constitutively expressed on phenotypically naive CD4+ T-cells, offsetting its role as an activation marker in the CD4 subset [26,27], was significantly lower in NKp44L+CD4+ T cells (28 ± 14%), than in their NKp44L− counterparts (46 ± 17%; P = 0.0025) (Fig. 2b). Importantly, we found no associations between NKp44L expression and any of our measures of CD4+ T-cell activation, defined by co-expression of CD38 and HLA-DR, or HLA-DR alone (Fig. 2c and data not shown). In addition, the frequency of CD127+ cells is similar related to NKp44L expression (data not shown). Overall, these data indicate that the disruption of T-cell subset maturation that is observed in InRs appears to be associated with NKp44L expression, but independent of the IL-7 pathway, despite the control of viral replication.
We next assessed the proliferative capacities of CD4+ T cells by analyzing expression of the intracellular proliferation-associated antigen Ki67. As expected, the proportion of Ki67+CD4+ T cells was significantly higher in CD4+ T cells expressing NKp44L (39 ± 20%) compared with the negative counterpart (5 ± 4%; P < 0.0001) (Fig. 3a). In contrast, the level of senescent CD4+ T cells expressing programmed-death 1 (PD-1) did not differ substantially in CD4+ T cells according to their expression of NKp44L (data not shown).
Some studies report that HIV-1-induced CD4+ T-cell depletion is mediated by Fas-FasL interactions. Thus, high levels of Fas (CD95) expression found in CD4+ T cells before HAART have been profoundly reduced after treatment [28]. Importantly, we observed significantly higher expression of Fas in NKp44L+ CD4+ T cells (92 ± 6%), than in negative cells (69 ± 16%; P = 0.0004) (Fig. 3b). Consistent with these data, annexin-V staining revealed a significant increase in apoptosis of NKp44L+ T cells (90 ± 8%), but not of NKp44L− cells (5 ± 3%; P < 0.0001) (Fig. 3c).
To gain deeper insight into the functional capacities of CD4+ T cells, intracellular cytokine profiles were assessed both before and after PHA or anti-CD3/CD28 stimulation. Specifically, we investigated the expression of IL-2, IFN-γ, and TNF-α in CD4+ T cells that did and did not express NKp44L. Figure 4a shows that intracellular cytokine expression was significantly higher in NKp44L+ cells, compared with NKp44L− cells. Interestingly enough, in the absence of stimulation, cytokine production remained close to the background level in NKp44L− cells but was sharply higher in NKp44L+ cells (Fig. 4a). After PHA stimulation, a high proportion of NKp44L+ cells, compared with NKp44L− subset, expressed IL-2 (69 ± 15% versus 9 ± 12%, respectively; P < 0.0001), IFN-γ (63 ± 14% versus 10 ± 11%; P < 0.0001), and TNF-α (64 ± 16% versus 10 ± 11%; P < 0.0001). Similar results were obtained after anti-CD3/CD28 antibodies stimulation (Fig. 4a).
We next determined the presence of CD4+ T cells expressing IL-2, IFN-γ, TNF-α or various combinations thereof by a multifunctional assay. Figure 4b shows that cytokine production was observed mainly in NKp44L+CD4+ T cells, with a greater tendency towards multifunctionality; most positive cells expressed some combinations of these cytokines. After stimulation by anti-CD3/CD28 antibodies or even later by PHA, a higher frequency of NKp44L+CD4+ cells expressed all three cytokines, compared with NKp44L− cells that were multifunctional only after PHA stimulation and then only slightly (Fig. 4b).
Up to 30% of HIV-infected patients show an incomplete response to HAART, and become InRs. In addition to the standard characterization based on clinical parameters reported in the Table 1, assessment of a comprehensive panel of immune markers on whole CD4+ T cells (Supplemental Fig. 1, http://links.lww.com/QAD/A347), very consistent with previous reports [2,6,29], confirmed the categorization of the patients in immunological responders and InR groups
This article suggested that InR status is associated with an expansion of highly differentiated, multifunctional CD4+ T cells expressing NKp44L, a cellular ligand for the activating NKp44 NK receptor [16]. Expression of this ligand is specifically induced by a highly conserved motif of the gp41 envelope protein of HIV-1 on CD4+ T cells from HIV-infected patients [16]. It might be mediated by low-level ongoing HIV replication and the subsequent presence of HIV antigens, including gp41, despite HAART, especially in tissues and lymphoid organs, as indicated both by theoretical considerations, and molecular analyses: detection of HIV mRNA in lymphoid tissue of patients on HAART with plasma viral loads less than 50 copies/ml [30–32], and of episomal HIV-1 infection intermediates in patients with undetectable plasma HIV RNA levels during HAART [33]. Notably, longitudinal measures of NKp44L expression before and after HAART clearly showed an inverse correlation between the CD4 cell count elevation and the progressive decrease of NKp44L expression after HAART [16]. Alternatively, an increase of NKp44L expression was associated with the CD4 cell count decrease in macaques infected with the SHIV162P3 [21].
The phenotype of NKp44L+ cells, combined with naive T-cell loss, is likely to reflect accelerated transitional proliferation of naive T cells into more differentiated effector memory cells. This bias toward more mature dysfunctional lymphocytes is in agreement with earlier studies reporting skewed CD4+ T-cell maturation in InRs, with an accretion of effector memory cells and a reduction of unprimed-naive T cells [2]. Thus, we set out to determine whether the differentiated maturation profile of NKp44L+ cells is associated with other major characteristics of CD4+ T cells observed in InRs. In fact, we observed that NKp44L+ cells display a heightened proliferative capacity. However, such effect might not result in higher CD4 cell count in InRs, as more than 92% of the NKp44L+CD4+ T cells were Fas+ and at least 90% stained positive for annexin-V, consistently with higher caspase-3 levels among the discordant patients [6]. In addition, the capacity of NKp44L+CD4+ T cells to secrete multiple cytokines (IL-2, IFN-γ, and TNF-α), compared with their NKp44− counterparts is consistent with the onset of a cytokine storm in InR NKp44L+ cells The abnormal cytokines production of NKp44L+ cells may be related to their important proliferating capacity, consistently with Combadière et al. [34]. Interestingly, patients with an immune reconstitution inflammatory syndrome (IRIS), have also a significantly higher fraction of multifunctional cells linked to increased IL-2, IFN-γ, and TNF-α T-cell responses, associated with a massive increase in the frequency of effector memory cells among CD4+ T cells reactive at the time of IRIS [35]. Thus, our functional and phenotypic results support the conclusion that highly differentiated, multifunctional NKp44L+CD4+ T cells are present in large numbers in some situations of uncontrolled falling T cell counts.
HIV infection was also characterized by high levels of immune activation, which could impair immunological recovery in course of HAART [8,36]. Interestingly, however, when evaluating activation pattern, HLA-DR+ and HLA-DR+CD38+ levels did not vary according to the level of NKp44L, despite trend to higher Ki67 expression. Notably, the proportion of CD4+CD38+ T cells is significantly lower in the NKp44L+ subset. Consistently, Scalza-Inguanti et al.[27] showed that CD4+CD38+ cells exhibit limited proliferation ability and a reduced capacity to produce Th1 cytokines, including IFN-γ, and TNF-α.
In line with our previous in-vitro and in-vivo investigations [12,18], our data on NK degranulation, associating NKp44 expression on NK cells, together with a high percentage of NKp44L on CD4+ T cells, could explain the T-cell depletion observed in such InRs patients. Knowing the sensitivity of NKp44L+CD4+ T cells to NK killing [16], the persistence of NKp44L expression could indicate why CD4+ T cells in those HIV-infected patients fail to revert to the phenotype found in immunological responders, despite 2 years of HAART. This discordant immune response linked to NKp44L, accompanied by the worse outcome and the faster clinical evolution observed in InRs, requires extensive further investigation. The establishment of a link between abnormalities in CD4+ T-cell differentiation, cell death, and NKp44L expression must encourage us to develop new therapeutic strategies to prevent the appearance of NKp44L and then to stimulate immune recovery in InRs.
We thank all of the clinicians and patients who participated in the study. The authors also thank Thibault Roguet, Anaïs Loubiere (Service de Médecine Interne. Hôpital La Pitié-Salpêtrière, Paris, France), Erell Guillerm, and Sophie Rondeau (Département d'Immunologie, Hôpital La Pitié-Salpêtrière, Paris, France) for providing blood samples to develop the assays. We are grateful to Christophe Parizot (Département d'Immunologie. Hôpital La Pitié-Salpêtrière, Paris, France), Dr Assia Samri, and Dr Laura Papagno (INSERM UMR-S 945, Paris, France) for excellent technical support and helpful discussion.
Author contributions: A.S., C.K., A.S., J.C., P.D. and V.V. conceived and designed the experiments; A.S. and F.B. performed the experiments; A.S., F.B., R.H.T.F., C.K., A.S., J.C., P.D. and V.V. analyzed data; A.G., I.N., R.C., C.K. and A.S. enrolled patients; and A.S. and V.V. wrote the article.
V.V. is a researcher from the Centre National de la Recherche Scientifique (CNRS). J.C. is chief executive officer of InnaVirVax, and R.H.F. is an employee of InnaVirVax.
The authors have no other conflicts of interest to disclose.
HIV-1; immunological nonresponders patients; NKp44 ligand
© 2013 Lippincott Williams & Wilkins, Inc.
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Alabama Agent Registration
Agent Policy
Professional Sports Counseling Panel
State of Alabama Registration
Current Student-Athletes
NCAA Rules and Bylaws
Agents Currently Registered with UA
Financial Advisors Currently Registered with UA
The University of Alabama Department of Intercollegiate Athletics seeks to provide its student-athletes every opportunity to succeed in professional sports. As a part of this commitment to the success of our student-athletes, the institution has elected to take a pro-active stance against agent interference, NCAA rules violations and legal issues involving agents and their intermediaries. As a result, we would like to take this opportunity to remind agents seeking future representation of our student-athletes of the following NFLPA regulations, state laws and institutional procedures regarding agent contact with current student-athletes:
The NFLPA has adopted a "Junior Rule," or Section 3(B) 30(a-c) of the NFLPA Regulations Governing Contract Advisors. This rule prohibits certified agents from contacting, directly or indirectly, non-draft-eligible college players or members of their family. Any violation of this rule or any other NFLPA regulation discovered by the University of Alabama will be reported to the NFLPA.
Further, Code of Alabama § 8-26A-4 states that an individual may not act as an athlete agent in this state without holding a certificate of registration issued by the Secretary of State. Code of Alabama § 8-26A-14 further defines prohibited athlete agent conduct. Such action jeopardizes the eligibility of our student-athletes, thus we take all such allegations seriously. Any violation of this statute can result in criminal prosecution, including possible felony charges. Violations will be reported to the Alabama Attorney General's Office for prosecution.
The University of Alabama also has policies and procedures to assist our student-athletes in the agent selection process. The University requires any athlete agent who wishes to represent our student-athletes to complete a Player-Agent Registration Form and submit said form to the Intercollegiate Athletics Compliance Office.
For further information on these programs, please contact either of the following:
Andrew BatteenCompliance AssistantUniversity of Alabama P.O. Box 870323 Tuscaloosa, AL 35487 205-348-3615
Mike WardAssociate Athletic Director - ComplianceUniversity of AlabamaP.O. Box 870323Tuscaloosa, AL 35487205-348-3639
Andrew BatteenCompliance AssistantUniversity of Alabama P.O. Box 870323 Tuscaloosa, AL 35487 205-348-3615
Mike WardAssociate Athletic Director - ComplianceUniversity of AlabamaP.O. Box 870323Tuscaloosa, AL 35487205-348-3639


text:
It was announced on the Raw Pre-Show that Ric Flair will be appearing on tonight's Raw from Richmond, Virginia.
Stay tuned to WrestlingNewsWorld.com for the latest Raw news and results.
Wrestling news, rumors, spoilers and results. We are a leading resource for WWE, TNA and everything related to pro wrestling.


text:
Most New Orleans Saints super fans are visual sensations, expressing their passion through an arresting display of colorful costumes and black and gold face paint.
Al d'Aquin chose a different way to express his lifelong
love of the Who Dats. He made his mark from a stage rather than the stands,
distilling his super fandom through one of
D'Aquin's alter ego, Abdul D. Tentmakur, ranks among the most famous Saints super fans thanks to his regular appearances on WWL-870. His character has become a perennial fan favorite and his songs have become popular rally cries before, during and after home games.
"It's always amazed me that something as simple as a football game could bring a city together like it did," said d'Aquin, 50. "We've always been that way about everything. Look at our food. Look at our culture. Our partying is far above anybody else's in the country. Our food is over the top. Anything we wrap our arms around we go above and beyond. It's the same with the Saints."
A corrosion specialist for British Petroleum Pipeline in
His career as a singing super fan was launched by a phone call to Buddy Diliberto's popular sports talk show on WWL in 1993. The Saints' surprising 5-0 start had stirred fans into a frenzy and prompted Diliberto's now-famous promise to wear a dress if the team earned a berth in the Super Bowl. In his inimitable way, Diliberto kidded that a tent-maker would be needed to construct the dress because of his renowned girth.
D'Aquin called the show as Abdul D. Tentmakur from
Abdul soon joined Sid from Jefferson and Bubba on the Magic Carpet as regular callers on the show. He would religiously call the "Point After" show on game days, whether it was from his car on the post-game commute home, a deer stand in Colorado or offshore in the Gulf of Mexico. He eventually started to pen parody songs about the Saints and play them live on the air.
His first song was "A House Called the Superdome," a riff on the Animals' "House of the Rising Sun," and it was so popular WWL officials asked him to write and perform a new song each week. Eventually he was invited to perform live at Buddy D's pregame show at the New Orleans Centre mall and a star was born.
Six CDs and more than 100 songs later, he's still singing away, usually in shrimp boots signed by former Saints stars Dalton Hilliard, Rickey Jackson and Bobby Hebert and always with his devoted wife of 30 years, Kim, nearby.
"It's great," Kim said. "It's so much fun for us, and I get the fringe benefits without having to do all of the work."
What started as a lark has carried d'Aquin to the stages of some
of the Gulf South's most revered institutions: Tipitina's; Birdie's Roadhouse
in Varnado; and the Flora-Bama Lounge in
His songs range in style from ballads to rock anthems but lyrically lean toward topical parodies of current events surrounding the team. His latest creation, for example, "The Grinch Who Stole Football," is satirical broadside to NFL Commissioner Roger Goodell, public enemy No. 1 among the Saints' faithful for his draconian punishments in the wake of the bounty scandal:
You're a mean one, Mr. Grinch.
Yeah, you have an evil heart
Your stupidity and your ignorance
Are off the freakin' charts.
You make Honey Boo Boo and Snookie look smart.
Well, you're a dumb one, Mr. Grinch
I think Snookie's IQ is higher
Well, you screwed us from the Super Bowl
We couldn't get hired.
Mr. Grinch, you should be fired.
He's written songs about nearly every top player including Willie Roaf, Sammy Knight, Joe Horn, La'Roi Glover, Kyle Turley, Deuce McAllister, Reggie Bush and Drew Brees. "What I Like About Deuce" was a spinoff of The Romantics' "What I Like About You." "Joe Horn Is Dynamite" was a take of Three Doors Down's "Kryptonite."
He counts among his favorites "The Buddy D Song," a eulogy he
wrote on the commute across the Causeway after learning of Diliberto's death in
2005, and "It's Different Down Here," a heartfelt ode to
"It takes certain players standing out or certain coaches
doing things for me to get my material," said d'Aquin, who moved to Vancleave, Miss., in 2008 but
remains heavily involved in the
There have been some twists and turns along the way.
The terrorist attacks of Sept. 11, 2001 forced him to
temporarily change his character name to Al from
In 2002, he was kicked out of a game by Superdome security because of an altercation with a Falcons fan.
And last spring his lighthearted parody of LSU Coach Les Miles landed him in hot water with some Tigers fans after the ugly loss to Alabama in the BCS championship game.
But all in all, the near 20-year-run has far exceeded his humble expectations. D'Aquin said he intends to scale back his public appearances next fall to three or four a season but he plans to keep playing professionally, primarily as a solo acoustic act.
"I've had a blast," he said. "I don't consider myself in any way share or form a celebrity. I'm just a local guy that hit a niche that made a lot of people happy. I was able to do some good."


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Leon Raymond Patry, loving father, grandfather, and companion, died Saturday, December 21, 2013, surrounded by his family. Born a twin in Toledo, on May 25, 1941, and raised in Medina, Leon was the son of the late Nita Arnold Patry and Maurice Patry.
Leon was a graduate of Medina High School in 1959 and attended Case University. After attending college, Leon committed his skills and expertise for more than 25 years at Adjustapost, where he retired as President and General Manager.
Enjoying an early retirement, Leon moved to Sun City in Bluffton, South Carolina, where he spent the winter months, but his heart always led him back to Put-In Bay, Ohio, where he was a life-long, part-time citizen. Following a family tradition spanning generations, from birth, he spent time on the island, and in retirement, he enjoyed every spring and summer there. Lee was a known presence by all, sitting on his porch in his rocking chair greeting passers by and looking out at the boats on beautiful Lake Erie.
Leon was an active member of Medina Morning Kiwanis for more than 25 years. He served as a consultant for numerous boards of directors for companies across the country, and he was active in S.C.O.R.E in both Ohio and Beaufort, South Carolina. Leon enjoyed volunteering at the Bluffton Police Department for 15 years as a liaison between the public and department employees. Leon also contributed to the Department by sponsoring a police dog through purchase of a protective vest.
Surviving are his loving companion of 17 years, Laura Borckardt; two daughters, Sheryl Lynn Patry and Marsha Lee Patry; and granddaughter, Anna Keltner Patry.
A memorial service was held Monday, December 23, 2013, at Sauls Funeral Home in Bluffton, South Carolina. An additional memorial service will be held in June in Put-In-Bay.
In lieu of flowers, memorials may be made to Bluffton Self Help, P.O. Box 2420, Bluffton, SC 29910, and Put-In-Bay Food Pantry, P.O. Box 248, Put-In-Bay, OH 43456.


text:
Teresa and Joe Giudice are both facing serious time behind bars following Tuesday's guilty plea.
Teresa is facing 21 to 27 months behind bars for her crimes, and her husband Joe is facing up to 46 months for his. However, when it comes to serving out their possible sentences, which will be made official on July 8 during their hearing, the Real Housewives of New Jersey couple wants to do their times separately for the sake of their daughters.
"[The Giudices] want to serve their prison terms separately so at least one parent can remain with their 4 children while the other is behind bars," TMZ reported on March 5.
Joe Giudice's attorney, Miles Feinstein, spoke to TMZ, stating that the couple plans to ask the judge to stagger their sentences with one serving their time before the other. Feinstein is confident the judge will grant the request and notes that the particular judge has done so in other cases.
Meanwhile, Teresa's attorney claims he and Teresa are aiming for probation as opposed to a jail sentence.
There have also been discussions of a possible house arrest for Teresa. That would allow her to remain at home with her daughters, ensuring they are cared for, while maintaining her businesses and continuing to film The Real Housewives of New Jersey.


text:
Bachelor of Computer Science
Details of major sequences
Cloud Computing - unit set code MJ-S000063
Burwood (Melbourne)
Cloud Computing is a significant development in the IT industry that is having a major impact on how software solutions are developed, deployed, and delivered over the web. You will undertake a study of the concepts and technologies of cloud computing and acquire the necessary expertise to work effectively in this field, both by exploiting public cloud infrastructure options and through the construction of private cloud infrastructure.
The major sequence incorporates the Cisco Certified Networking Associate (CCNA) curriculum that trains you in the skills needed to construct and maintain network infrastructures to effectively support organisational needs.
Subject areas include: cloud computing and virtualisation, computer security, enterprise network construction and management, system security and research and development in IT.
|Cloud Computing and Virtualisation
|Introduction to Computer Security
|Enterprise Network Construction
|Enterprise Network Management
|Research and Development in Information Technology
|System Security


text:
3 Oct 05:51 2006
Updated: bash-3.1-9
Eric Blake <ebb9 <at> byu.net>
A new release of bash, 3.1-9, is now available, replacing 3.1-8 as the current version. 3.1-6 remains as the previous version. NEWS: ===== Due to complaints on the mailing list, this version attempts to alleviate some of the pain of people who have difficulties working around \r\n line endings in scripts residing on binary mounts. First, if a script is specified with a DOS path instead of a POSIX path (although this is not the recommended behavior in cygwin), bash will ensure that the underlying mount mode is respected, rather than the default cygwin behavior of using binary mode, allowing the use of DOS paths on text mounts the way 3.1-6 behaved. Second, this release adds a new shopt, igncr, which dynamically tells bash to ignore all \r in the input file when it is set; however, it defaults to unset. With this shopt, it is possible to make a bash script work on binary mounts even if it has \r\n line endings, by adding the following line as the first non-comment: shopt -s igncr;# The comment is necessary since bash parses a line at a time before processing shopt, so you want to avoid interpreting the last potential \r literally before the change takes place. If you want your script to be portable to other platforms or shells that don't understand igncr, you can write it as: (shopt -s igncr) 2>/dev/null && eval 'shopt -s igncr';# For now, the igncr shopt is only documented in this mail; I thought it better to get 3.1-9 out the door than to spend time also patching the online documentation and delaying the release. It is also a chance for any feedback to the list to influence whether I need to make 3.1-10 in the near future.(Continue reading)


text:
Tonys 2012: 'Columnist' Star John Lithgow on (Not) Winning
On the red carpet at Sunday's Tony Awards, John Lithgow predicted he would lose in the best play category category to one of his rivals: Philip Seymour Hoffman; James Earl Jones; Frank Langella or James Corden.
(Corden, the relative newcomer from One Man, Two Guvnors, won the trophy in an upset victory over Hoffman.)
But Lithgow, who already has a Tony under his belt, was pleasantly resigned to his fate, raving about his role as a '60s-era political journalist in The Columnist and making plans to do more Shakespeare in the future.


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French bistro fare meets Old World design and contemporary touches at Seth Greenberg and Cameron Grob's new Bastille Kitchen in Boston's Fort Point Channel, a large restaurant at 49 Melcher St. with 11,000 square feet and a separate downstairs bar/club space that can be booked for private events.
There's a lot going on here, from the bistro-style cuisine of Chef Adam Kube, a former sous chef with The Ritz-Carlton Hotel, to the well-designed wine list from GM/Sommelier Michael Adkins to the variety of spaces and settings for dining, networking and drinking.
Somerton Park Interiors' Petra Hausberger, principal, creates a mix of old and new between the portrait of Marie Antoinette, the black, white and burnt crimson orange color touches, and the bench seating, brick walls and iron wall sconces. The black and white herringbone fabrics on a long banquette that creates a focal point in the restaurant pairs well with hard oak European tables and the 11-foor long high-top in the primary dining area, which offers the opportunity for large parties and communal socializing.
Executive Chef Kube, one of Zagat's 30 Under 30 this year, and General Manager and resident Sommelier Michael Adkins bring their talents and backgrounds to the new venture to create a very French menu that offers Bostonians the seafood options they love and a great array of appetizers, plus a selection of choices from Old World-style wine producers from America and Italy. There is a lot to take in at Bastille Kitchen!