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Chief Designer Vladimir Chelomei began development of the UR-100N in 1967 as a replacement for his UR-100, the most widely deployed Soviet ICBM. He conceived of a modernised 8K84M capable of launching six independently-targeted nuclear warheads. Chief Designer Yangel at KB Yuzhnoye was promoting an alternate UR-100 replacement, his MR-UR-100. The competition between the two chief designers led to a drama universally remarked upon in memoirs of Soviet rocketeers. Both design bureaux had powerful supporters in the Soviet leadership, and no consensus could be reached as to which missile to put into production. Chelomei was supported by leadership figures Grechko, Afanasyev, and designers Sergeyev, Barmin, Baryshev and V Kuznetsov. The Yuzhnoye design was supported by Central Committee Secretary Ustinov, head of the VPK Military-Industrial Commission Smirnov, Mozhorin, Tyulin, and designers Glushko, and Pilyugin.
Keldysh headed an expert commission to select a design, but the split within the technical community resulted in a deadlock. Premier Brezhnev finally made the Solomonic but extremely expensive decision at a leadership meeting at Stalin's old dacha at Yalta -- both would be built and deployed.
Decrees authorising full development of the missile and silo were issued on 2 September 1969 and 19 August 1970. The missile was to feature a manoeuvrable post-boost bus for dispensing of warheads and countermeasures on different trajectories; a digital guidance system by V Sergeyev at NII-692; and shock mounting of the missile in the silo to improve survivability and the allow it to ride out an enemy counter-force nuclear attack. The rocket itself was increased in diameter to 2.41 m. The second stage engine was completely 'submerged' in the fuel tank, to allow the maximum missile mass to be packed into the existing UR-100 silos. This nearly tripled payload compared to the original UR-100. Baryshev at TsKBM Filial 2 designed the silo modifications. The new universal missile command point was designed by Krivoshein and Aksyutin at TsKB TM. The miniature nuclear warheads were the product of NII-1011 at Chelyabinsk-70.
Test flights began on 9 April 1973 at Baikonur. The last of 27 test launches were completed in October 1975. During the series tests were made with 1, 4, and 6 warhead configurations. The first regiment became active with the missile at Pervomaisk on 26 April 1975. The missile was formally accepted by the military on 30 December 1975. The first regiment with improved 'super-hardened' silos, able to resist overpressures of up to 450 atmospheres, became operational at Tatischevo on 18 December 1976. By 1979 240 missiles had been deployed. The INS, based on that developed for the R-36M by NPO Kharton, provided an 0.26 km CEP.
In service the missiles received a minor inspection and preventive maintenance visit every three months. A major inspection and maintenance is conducted every three years. The UR-100N was launched a total of 67 times by the year 2000. These included regular service launches to verify the missile's guaranteed life. In November 1994 a missile was launched successfully after 18 years in its storage container. A 10 June 1997 a twenty-year old missile, moved in its container from a silo in Kozelsk, was launched from Baikonur, followed by a 22 year old missile on 7 October 1998. These tests resulted in the missile being certified for 25 years life in 1999, which would allow field use of the UR-100N to 2010. There was every expectation that this could be extended to 30 years.
With the collapse of the Soviet Union, 130 UR-100N's at Khmelnitskiy and Pervomaisk had their warheads removed. The rockets themselves were returned to Russia between 29 August 1996 and February 1999. By September 1998 120 of the Ukrainian silos had been destroyed. The missile remained in service in 160 silos in Kozelsk (70) and Tatishchevo (90).


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Issues For and Questions About the a11yspec Template
General Issues Which Need to Be Addressed for All Specifications
- boilerplate "copyright" and "licensing" verbiage -- get from from LF?
- status: to be resolved 29 January 2008 Does the Creative Commons License, suggested by Dan Kohn, sufficient?
- if issuing software or libraries, use: GNU General Public License, Version 2
- is there a boilerplate LF template?
- no
- should the boilerplate template be Open A11y specific?
- status: yes, to the greatest extent possible
- we obviously want to use the Open A11y logo -- what about the LF logo? is it required?
- status: use of the LF is not, required but appreciated
- is verbiage needed re: trademarks of companies, interested parties, implementors?
- status: no boilerplate text available from LF
- need boilerplate "status of this document" declarations
- status: under consideration
- is any other boilerplate material needed?
- status: under consideration
General Issues Which Have Been Answered
- the feedback address for all Open A11y specifications will be firstname.lastname@example.com
- the feedback address will be included in each specification's Introduction (after verbiage such as "this specification was developed by the LF/Open A11y Keyboard Committee/Subgroup/SIG. To provide feedback, report errors or inquiries, please send email to firstname.lastname@example.com" and in the
ADDRESSsection of the specification.
- the feedback address will be included in each specification's Introduction (after verbiage such as "this specification was developed by the LF/Open A11y Keyboard Committee/Subgroup/SIG. To provide feedback, report errors or inquiries, please send email to firstname.lastname@example.com" and in the
KAFS-specific Issues
- in the auto-generated version of the spec, 'class' is used extensively as a pseudo-semantic attribute -- that practice can be continued, but it is best if the anchors have some meaning in and of themselves rather than an alphanumeric code, as is currently the case. the other options is to use RDFa or simply use the
id/namebinding? i have removed the "emphasis" class from the
Ielements and converted them to
EMtags to which specific styling can be applied; for example the
Ielement was used to demarcate concepts such as StickyKeys, BounceKeys, etc. was classed as "emphasis" -- this should be classed as "spec-term" or "concept" or something similar
- we want to (at least) use dublin core markup in the
HEADvia the meta element, right? (note that empty content fields are those i felt better populated by the editors)
<meta name="DC.Title" content="Keyboard Access Functional Specification, RC2" /> <meta name="DC.Title.Alternative" content="" /> <meta name="DC.Creator.PersonalName" content="Earl Johnson, Sun Microsystems, Inc." /> <meta name="DC.Creator.PersonalName" content="Bill Haneman, Sun Microsystems, Inc." /> <meta name="DC.Creator.PersonalName" content="Mark Novak, University of Wisconsin, Madison" /> <meta name="DC.Creator.PersonalName" content="Willie Walker, Sun Microsystems, Inc." /> <meta name="DC.Subject" content="Functional Specification" /> <meta name="DC.Subject" content="Keyboard" /> <meta name="DC.Subject" content="Keyboard Input" /> <meta name="DC.Subject" content="Alternative Input" /> <meta name="DC.Subject" content="system pointer" /> <meta name="DC.Subject" content="keyboard accessibility support" /> <meta name="DC.Subject" content="keyboard notification" /> <meta name="DC.Subject" content="Configuration and Setting Requirements" /> <meta name="DC.Subject" content="End-User Notification Requirements" /> <meta name="DC.Subject" content="Keyboard Invocation Requirements" /> <meta name="DC.Subject" content="Pointer Emulation Requirements" /> <meta name="DC.Subject" content="Feature Behavior Requirements" /> <meta name="DC.Subject" content="StickyKeys" /> <meta name="DC.Subject" content="MouseKeys" /> <meta name="DC.Subject" content="RepeatKeys" /> <meta name="DC.Subject" content="SlowKeys" /> <meta name="DC.Subject" content="BounceKeys" /> <meta name="DC.Subject" content="ToggleKeys" /> <meta name="DC.Subject" content="Linux Foundation (LF)" /> <meta name="DC.Subject" content="LF" /> <meta name="DC.Subject" content="LF Certified" /> <meta name="DC.Subject" content="X Windowing System" /> <meta name="DC.Subject" content="" /> <meta name="DC.Subject" content="" /> <meta name="DC.Subject" content="" /> <meta name="DC.Description" content="This functional specification defines the support that must be built into the system. The capabilities provided by the features in it define the pointer based events and capabilities that must be emulated by the system as well as how the system should interpret and process a user's keypresses. For the most part, defining and/or specifying the exact user interface[s] these features are presented in is beyond the scope of this specification. The one exception area is keyboard shortcuts that are already considered de facto standards. These shortcuts are explicitly defined." /> <meta name="DC.Publisher" content="Open Accessibility (A11y) Workgroup of the Linux Foundation" /> <meta name="DC.Rights" content="" /> <meta name="DC.Type" content="Text" /> <meta name="DC.Format" content="text/html" /> <meta name="DC.Identifier" content="http://accessibility.linux-foundation.org/a11yspecs/kbd/keyboard-access-func-spec.html" /> <meta name="DC.Language" content="us-en" />
when last this issue was discussed, the closest thing GJR had found to a "stable" reference was an 18 November 1997 date-stamped WayBackMachine archived copy of the original directory, complete with both: allchaps.ps and allchaps.pdf which
can be found at:
Specific MarkUp Issues
- the document-type of Open A11y specifications will be XHTML 1.0 Strict
- all tables used in a specification must contain (at least): a
scopeand a
CAPTION; styling of tables should be handled with CSS, rather than be hard-coded into the
- all tables used in a specification must contain (at least): a
- expansions must be provided for all acronyms and abbreviations
- all Open A11y specifications '''must''' contain an
ADDRESSelement, containing: contact information, means of providing feedback, reporting errors, etc.. The
ADDRESSwill also contain boilerplate Open A11y/Linux Foundation verbiage as far as copyright and permissions are concerned, as is common at the bottom of technical specs
- all Open A11y specifications need a normative references section. For example, to document RFC2119 in the text, the string RFC2119 should point to an entry in the Normative References section. This will assist in the stability, longevity and maintenance of the document, as the links contained in the text will not be broken when a resource moves or a URI changes, but can document when the resource was accessed and make it easier to universally effect a change to a single URI through an accompanying errata document. (a note on the example: this is supposed to be an example of code contained in a
DL, but since the wiki allows certain HTML/XHTML markup without using
HTMLcontainers normally used to insert straight markup into a wiki page, and i have yet to be able to get the markup example to be rendered correctly)
- [RFC2119]

- Key words for use in RFCs to indicate requirement levels,
RFC 2119, S. Bradner, March 1997.
Available at: http://www.rfc-editor.org/rfc/rfc2119.txt

- a unified "look-and-feel" (as well as sounds for aural styling, which can be added later without affecting the spec) needs to be established
- it is strongly recommended that CSS be used for controlling the printed version of the spec when printed from the XHTML document?
Syntaxic Conventions for Open A11y Specifications
- all Open A11y specifications will conforms to RFC2119 to specify declarative, normative keywords, for example:
- The keywords "MUST", "MUST NOT", "REQUIRED", "SHALL", "SHALL NOT", "SHOULD", "RECOMMENDED", "MAY", and "OPTIONAL" in this document are to be interpreted as described in [RFC2119].
- all anchor values must be lower-case
- any anchor
idmust be human-parseable
- when a term is defined, the anchor to that definition should take the form
def-foo, where
foois the concept's name; for example,
- when a term is defined, the anchor to that definition should take the form

subset: commoncrawl


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Global Rating: 4.00 from 1 reviews.
|City State/Province Country
|Runs a little small (4/5)
|Nov 8, 2013
|Carolina Glade
|Alexandria VA US
I got this leotard because I'm a C cup in a small body, so I need extra support and don't feel comfortable with leotards with any support.
I ordered a small size, but it should have been a medium because it fits way too tight at the closure. The good thing is that it can be fixed by using a regular bra extension. That is the only reason why I don't rate it 5 stars. It is very comfy and the fabric fits nicely.
My advice, get one size bigger than your regular leotard size.
Add your own review for this product
Go Back to Capezio Camisole Leotard w/Bratek


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Professor and Neurology Chair
Primary Department Affiliation: Neurology
Primary Research Area: Neurodegeneration and Neurodegenerative Disorders
Neurotransmitter and Neurotrophin Receptors and Cell Signaling
Systems Neuroscience and Vision
Recent Publications
Dr. David Standaert joined our department on July 1, 2006, from the Department of Neurology at Massachusetts General Hospital/Harvard Medical School as the John and Juanelle Strain Professor of Neurology and Director of the newly established Center for Neurodegeneration and Experimental Therapeutics and the Division of Movement Disorders. Dr. Standaert is an internationally renowned physician scientist whose work focuses on understanding the causes of Parkinson's Disease and other Movement Disorders with the goal of developing new treatments. He is also an outstanding Movement Disorder Neurologist and he will have a subspecialty practice in UAB's Kirklin Clinic.
Dr. Standaert brings a very distinguished academic background…Honors graduate of Harvard College, graduate of the Washington University School of Medicine Medical Scientist Training Program with an MD/PhD in Pharmacology, graduate of the University of Pennsylvania Neurology Residency Program, and graduate of a research and clinical Fellowship in Movement Disorders at Massachusetts General Hospital/Harvard Medical School before joining the faculty there.
As Director of the American Parkinson Disease Association Advanced Center for Parkinson Research at Massachusetts General Hospital (MGH), his laboratory was working on understanding both the root causes of Parkinson's disease as well as origin of disabling symptoms appearing after long-term treatment of the disease. He also saw patients in the Parkinson Disease and Movement Disorders Clinic at MGH. Similarly, Dr. Standaert will be continuing with his research and seeing patients with movement disorders at UAB.
Dr. Standaert's laboratory is working on understanding both the root causes of Parkinson disease (PD) as well as the origin of the disabling symptoms that appear after long term treatment of the disease. The lab has a strong translational orientation – our goal is to accelerate the delivery of new therapies for Parkinson disease to the patients who desperately need them
A primary focus of the laboratory is understanding the role of the protein alpha-synuclein in PD pathophysiology, and searching for novel approaches for protecting the brain from the effects of excess alpha-synuclein. We use a variety of cellular and rodent models, and are exploring the effects of several chaperone molecules, including those derived from open-ended screens in simple non-mammalian systems.
A related interest is the role of neuroinflammation in PD. In human PD, there is a marked brain inflammatory response. Recent work in the Standaert lab using mouse models has led to the idea that this inflammation may be triggered directly by the presence of excess alpha-synuclein. The response involves both microglia as well as the adaptive immune system, and both components may be targets of therapies to prevent or retard the disease.
We are also exploring the effect of levodopa on brain function in PD. Levodopa remains the most effective existing treatment, but long-term therapy leads to many unwanted side effects ("wearing off" and "dyskinesia"). The Standaert lab has shown that many of the effects result from abnormal synaptic plasticity in the basal ganglia, and mislocalization of glutamate receptor systems. Recently, we found that the mechanisms responsible for the maintenance of this aberrant plasticity is likely the result of levodopa-induced epigenetic modifications.


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I Am So Lucky That I Get To Ride My Bike: Lessons from the Dirt
Submitted by Cheri Felix on
I went out for a ride the other day with a bunch of girls. It was one of those days where you inhale the dirt and the smell of the pine and you think, "I am so lucky to be out here on my bike." I have those days all of the time because I have certain reminders in my life to remind me of how lucky I am; a mother who had a stroke at age 49 and later died at age 58 from ovarian cancer and a father who is dying of emphysema. Not that he would have ever ridden a bike but he can't for sure now. I guess my point is that I don't have to look far to see the privilege I carry to ride my bike, to have a bike and to have some great trails and some great girlfriends to share my passion. And a super supportive husband I might add.
Mountain biking for me has always been about freedom. It's like I'm a kid again except I'm carefree without a mortgage and a car payment and a grocery bill larger than I'd like to admit. I've done a lot of healing on my bike and I've cried on my bike. I used the bike as a therapy tool when my mom died. I've used it as a means to get back into shape after each of my three babies. I use it when I can't quite seem to shake something out of my head. And I've used it for out and out fun. The other day while on the trail I heard my friends say, "Oh my god, this makes me so happy." Yep. That about sums it up. I've seen some of my women friends transformed by learning to love mountain biking. And when I say "transformed" I mean it. The grace and the humility and the strength that you use and experience in mountain biking carry into each and every part of your life. You are reminded to not take anything too seriously and you are reminded time and time again that you are a) lucky to be alive and b) more amazing than you know.
Now you might be thinking, "Really? You get all of that from riding two wheels on dirt?" You betcha your sweet tire pump I do. And I reckon I'm not alone. I imagine there are a whole bunch of girls out there just like me. Not the fastest, not the best but totally passionate about mountain biking. Lately I've had the pure pleasure of riding with friends who are just now tasting the sweet nectar of mountain biking. Just getting to feel what I'm talking about. It's like watching a toddler take their first steps; it's as exciting as it is frightening. The next time you're feeling down or you feel like it's the same old ride on the same old trail on your same old bike, take a friend with you. Or just remind yourself about how lucky you are.
In the past week I've been reading updates about a young woman who crashed during a ride, I've been taken aback at how affected I am by her situation. I mean don't we all go out for a ride totally expecting to follow it up with a beer, a latte or just some time on the couch. The mother in me catches my breath and chokes with tears every time I read the update from her hospital room. Every ounce of my good thoughts this week goes to her and to her family and to her amazing supportive friends.
I just know some day she'll get to use her bike to work all that out and some day it might be her that says, "Oh my god, this makes me so happy."
News Item:
1 Comment
biking makes me happy too!
Submitted by Shelly (not verified) on
AMEN SISTA! I LOVE the way it clears my head, makes me feel strong, gets me outside with my friends, ... thanks for the reminder that we are so lucky that we get to ride our bikes.
Points: 9


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Cloud Computing
Extend Your Data Center to the Cloud
VMware vCloud Air and VMware vCloud Air Network Service Provider partners are delivering on the promise of hybrid cloud computing, enabling you to seamlessly and securely extend your data center and applications to the cloud. With cloud services built on the trusted foundation of VMware technology, you can provision new or move existing workloads between onsite data centers or internal private clouds to the public cloud, and back again as needed, creating a true hybrid cloud. VMware provides unprecedented flexibility and choice of cloud services on a local basis with vCloud Air and through the vCloud Air Network--the world's largest network of validated cloud services based on VMware technology.
The Advantages of Hybrid Cloud
When you choose cloud services from VMware and our vCloud Air Network Service Providers partners, you don't have to worry about application compatibility or service provider lock-in often associated with other commodity cloud services. You reduce both risks and costs without requiring additional management tools and infrastructure, reinventing your processes or retraining your existing workforce. The benefits of a VMware-based hybrid cloud platform include:
- The ability to write, deploy and manage applications in the cloud the same way you do today, relying on the underlying platform to provide the same level of security, reliability and performance you get from your current VMware infrastructure.
- Administration of the entire hybrid infrastructure—data centers and public cloud together—with a "single pane of glass" management framework. Use the same tools, processes and skills you already have.
- Quickly deploy workloads to the cloud with the flexibility to move them between your on-premises and off-premises environments as your requirements change.
- Global availability and choice of validated cloud services through VMware or our vCloud Air Network service provider ecosystem.
- Data sovereignty through local vCloud Air data centers and vCloud Air Network service providers in 102 countries.
VMware Hybrid Cloud Solutions
VMware vCloud Air
Run any workload, existing or new, with the VMware vCloud Air —a secure, dedicated cloud owned and operated by VMware. Built on the trusted foundation of VMware vSphere, the service delivers unified networking that spans between your existing and new data center capacity, common management and security, with the same reliability and performance you expect from your internal data center.
vCloud Air Network Service Providers
Choose from a broad selection of cloud services built on the industry-leading vSphere virtualization platform. These services are optimized for a variety of use cases, such as seasonal projects, development and testing, disaster recovery and mission-critical applications.


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Joined IHG® Rewards Club at a Hotel?
Joining is easy and free
Earn points at over 4,700 hotels
Redeem points for free rooms and more
Contact your local IHG® Rewards Club Customer Care to source your PIN and to update your profile with your email address. When you receive your PIN you can also update your email address via www.ihg.com/updateemail.
Reward Nights
When redeeming points for a Reward Night, you may only book one room at a time.
Once you complete your Reward Night reservation you will be given the option to duplicate this reservation.
* Requires affiliation in the respective organization.
** Best Available Rate Search does not include affiliation rates.
To book more than 9 rooms for one stay or request a quote, please use our Easy Meetings tool, call 1-800-MEETING (in United States, Mexico and Canada) or contact a Global Sales Office.
Welcome to the Holiday Inn Express® Carson City hotel. Located just off HWY 395 and north of downtown Carson City, our hotel is perfect for business and leisure guests alike. We're also conveniently situated near Virginia City, Reno and Lake Tahoe.
Corporate hotel guests find that we serve their every need. Since we're near downtown, our patrons can easily get to all the major government buildings, including the Nevada State
View More
Corporate hotel guests find that we serve their every need. Since we're near downtown, our patrons can easily get to all the major government buildings, including the Nevada State Capitol Building, Supreme Court of Nevada and the Nevada Legislature Building. We are also less than a mile from the Carson Tahoe Regional Healthcare and Cancer Center. A meeting room large enough for 40 and a well-equipped business center are available, as well.
In addition to being close to Reno and Lake Tahoe, our hotel is near great local attractions, too. The Carson City Nugget, just two miles away, has gambling, live music and fabulous shows. Don't miss the Children's Museum of Northern Nevada or the newly reconstructed, historic V&T Railway going into Virginia City. Stay with us and you'll see why people love to come back to Carson City. Our pet-friendly hotel is equipped to pamper you with an indoor heated pool and whirlpool, and every morning we offer a free, hot breakfast bar. With an extra large parking lot, a 24-hour fitness center and free high-speed, wireless Internet access in every room, you'll soon see why we're one of the best hotels around.


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Robert West memorial service scheduled
Published: Wednesday, June 12, 2013 at 12:19 p.m.
Last Modified: Wednesday, June 12, 2013 at 12:19 p.m.
WILMINGTON | A memorial service for Robert West will be 2 p.m. Saturday, June 22, at the Cameron Museum of Art, 3201 South 17th St. It will be followed by a celebration that he planned at 602 S. Fifth Ave, his home and headquarters of Working Films.
West was co-founder of the Wilmington-based nonprofit Working Films, which uses documentary films as instruments of social change by connecting filmmakers with people motivated to work on the issues.
Those coming from out of town can contact Andy Myers at firstname.lastname@example.com or (910) 342-9000 for information about hotel rooms.
– Si Cantwell
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.


text:
For the more information about the geologic resources of the National Park Service, please visit http://www.nature.nps.gov/geology/.
Email List
The Cave-karst listserve is to be used to "promote collaboration and communication among national park and network staff and collaborators on the topic of monitoring and stewardship of cave and karst resources". As a reminder, this is a listserve that is open to the public for both viewing and membership. As such, we get the opportunity to share what is happening in America's cave and karst parks with the world, but should keep internal NPS communications off this list.
How to subscribe or unsubscribe from the [Cave-karst] email list:
If you are not currently a member of this list and you would like to subscribe, please visit http://webmail.itc.nps.gov/mailman/listinfo/cave-karst and follow the instructions listed to sign up.
If you are currently a member and wish to unsubscribe or edit your options to receive emails in digest mode, please visit http://webmail.itc.nps.gov/mailman/listinfo/cave-karst and follow the instructions listed at the bottom of the page.
Related Links
Last Updated: November 26, 2013


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La Monnaie ¦ Opera ¦ La Dispute ¦ Intro
La Dispute
Benoît Mernier
The inconsistencies of love, do they stem from man or woman? This is the question underlying Marivaux's La Dispute, one of his most disconcerting and incisive plays, which constitutes the core of the libretto of Benoît Mernier's second opera. To finally resolve this burning philosophical issue, a diabolical experiment brings together four youngsters raised in isolation from the world and, before our eyes, discover love and their first betrayals. For this work, the Belgian composer collaborated closely with the librettists Ursel Herrmann and Joël Lauwers. This gives him the opportunity to again grapple with the awakening of desire following on from his Frühlings Erwachen in 2007. Conducted by Patrick Davin, this Dispute is directed by the Herrmanns, taking on a contemporary work for the first time.
World premiere
© Gaétan Charbonneau / Millennium Images, UK


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Photo Information and Commencement Video
Ceremony Webcast
A live and archived webcast of the ceremony will allow family and guests who were unable to attend to watch the ceremony in the comfort of their home.
Graduate Photos
A professional photographer will take pictures of individual graduates as you receive your diploma. The pictures will be made available for order and purchase approximately one week after graduation. Genesee Photo Systems will contact you by mail at your permanent home address. You can also go to the link below, view and order individual photos at www.geneseephoto.com
Ceremony Photos
The Sage Colleges Communications and Public Relations Office will post after the ceremony.


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Companies in mail-heavy markets like finance, insurance, utilities and telecom want improved efficiency and automated workflows but need help getting there
Malvern, PA, April 8, 2013 - Inefficiency, errors and compliance issues often plague companies that print and distribute high volumes of customer-facing transactional mail such as invoices, checks and account statements. These companies often suffer high costs, sluggish cash flow and, in the worst case, angry customers and regulators.To help organizations confront these challenges, Ricoh Americas Corporation today detailed its Document Production Center Optimization services, which help clients reduce costs in transactional printing and distribution while improving accuracy and utilizing its client's existing technology, whenever possible. Ricoh Document Production Center Optimization services transform inefficient print, mail and distribution processes – driven by unwieldy data – into predictable, efficient and highly scalable workflows. The services exemplify Ricoh's Business Information Solutions approach, which tailors custom solutions to clients' most urgent business challenges. Ricoh Document Production Center Optimization services support Gartner's "Automated Document Factory 2.0 (ADF 2.0)" architecture, which is considered the state of the art in transactional printing/mailing. "Large-scale print and mail operations present the face of your brand to your customers and may have a significant impact on your cash flow," said Dominic Pontrelli, Senior Vice President, Marketing, Ricoh Americas Corporation. "Many companies lack the resources to bring the required systems and processes together in an efficient way. We offer operations benchmarking services and powerful workflow solutions based on each client's unique needs whenever possible using the technology they already have." People, processes and technologyRicoh Document Production Center Optimization services combine people, processes and technology to bring this new efficiency to clients' printing and distribution operations. Engagements kick off with an assessment of the current state of the client's printing and distribution. Ricoh's services team employs a unique operations benchmarking service to investigate baseline performance and customer satisfaction. This process helps clients rapidly pinpoint exactly where their systems need optimization. Ricoh's goal is helping to create an efficient, productive printing and distribution operation based on the Automated Document Factory model. Ricoh's ADF solutions automate every stage of production, including data assembly, formatting, printing, finishing and mailing. They offer end-to-end process control, monitoring and reporting that can easily integrate with CRM and marketing campaign systems. Ricoh's modular, scalable ADF solutions let clients see, manage and report on their entire document production center operation from a single dashboard.Ricoh's technology includes a cloud-based ADF solution, an alternative for simple, quick and worry-free workflow optimization without high upfront IT investment. Other key technology includes Ricoh Process Director™ print management software, production print systems and mail automation software. Document Production Center Optimization solutions can support sustainability initiatives and their associated cost savings by helping clients move beyond print and automate electronic delivery. Whether using traditional mail or electronic, communications can employ TransPromo (transactional and promotional) content for increased marketing effectiveness.Ricoh's experienced consultants have been designing, implementing and maintaining ADF Solutions for nearly 20 years, including more than 100 ADF solutions implemented worldwide. Clients include some of the world's largest insurance, financial, telecom and print services companies, as well as departments within the U.S. government. Clients benefitting from Ricoh Document Production Center Optimization services include AIGDirect.com, Blue Cross Blue Shield, Express Scripts, Geisinger Health System, Los Angeles Department of Water and Power and Undurraga. About Ricoh's Business Information SolutionsThrough extensive analysis and experience, Ricoh has identified the major business challenges enterprises are facing today: globalization, increasing employee mobility, new generational work styles, exploding information volumes, mounting cost pressures and rapid IT infrastructure changes. The company directly addresses these challenges with its Business Information Solutions approach, which brings together technologies, services and expertise that can help to measurably improve business performance by optimizing the flow of business information.The Business Information Solutions approach streamlines an organization's entire information workflow by improving:• Input – capturing valuable information from employees, customers and partners.• Processing – creating business value from information. • And Output – distributing the information to the right person at the right time in the right form for productive action.For details on Ricoh's full line of products, services and solutions, please visit www.ricoh-usa.com.| About Ricoh |Ricoh is a global technology company specializing in office imaging equipment, production print solutions, document management systems and IT services. Headquartered in Tokyo, Ricoh Group operates in more than 200 countries and regions. In the financial year ending March 2012, Ricoh Group had worldwide sales of 1,903 billion yen (approx. 23 billion USD).The majority of the company's revenue comes from products, solutions and services that improve the interaction between people and information. Ricoh also produces award-winning digital cameras and specialized industrial products. It is known for the quality of its technology, the exceptional standard of its customer service and sustainability initiatives.Under its corporate tagline, imagine. change. Ricoh helps companies transform the way they work and harness the collective imagination of their employees.For further information, please visitwww.ricoh.com/about/###© 2013 Ricoh Americas Corporation. All rights reserved. All referenced product names are the trademarks of their respective companies.
Contacts:Jill SearlJohn GrecoBrodeur PartnersRicoh Americas Corporation(603) 559-5824(973) firstname.lastname@example.com@ricoh-usa.com
* If you don't have Adobe Reader, you can download free.
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Results tagged ' Korea '
The Japanese Revolution
For all the apathy I have shown towards the World Baseball Classic this year (not commenting on it once on this blog until now), there is one thing that both installments of the tournament have clearly shown me: the Japanese style of baseball is the most effective at winning ballgames.
Now, of course I realize that if the United States team really did choose all our best players, and if guys like Johan Santana and David Ortiz wouldn't bug off the Dominican Republic squad, the tournament may play out much differently. However, even if each team's best possible squad was on the field every day, I think Japan could compete with any of them. Their small-ball, advance-the-runner style of play (plus, nearly every player can run the bases effectively) has really become the sought-after way to win games. I mean, how fitting was it that Ichiro Suzuki (the player who best personifies the Japanese game) got the game-winning hit against Korea?! I've never seen a batter where luck plays as big a role at getting him out. Since he never strikes out, retiring him requires the luck of the ball-in-play being hit right to a defender…that's about it. Pitchers may have learned his tendencies a wee bit, but now he "just" hits .320 every year instead of .350, and has 220 hits instead of 257.
When Jackie Robinson broke the color barrier back in the 1940s, it completely changed the way baseball looked, as it allowed black players to increase the quality of play. What's interesting is that you can almost say that the same sort of thing happened to the Japanese market in 2001 when Ichiro hit the major leagues and brought his much more exciting brand of baseball to a game then bogged-down by steroid oafs. Now, Japan is continuing to get the recognition they deserve, and you can bet that many more single-hitting, base-stealing, wacky-delivery Japanese players will be popping up on rosters all over MLB.


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Brunswick Sheriff's Office needs help identifying car, driver
Published: Thursday, May 9, 2013 at 4:45 p.m.
Last Modified: Thursday, May 9, 2013 at 4:45 p.m.
CALABASH | The Brunswick County Sheriff's Office is asking for the assistance in identifying the vehicle or person in this photo. The person is a possible suspect in the theft of a tractor-trailer from Wayne's Backhoe in Calabash that took place within the past two weeks. Anyone with information should contact Det. John Holman at (910) 253-2777.
– Kate Elizabeth Queram
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The eurozone is battling a financial crisis that has seen several countries unable to repay or refinance their government debt. Five EU member states have so far had to resort to international bailouts to see them through.
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Recent Activity
May 18, 2011
This awards ceremony, honoring the 2011 recipients of the E Pluribus Unum Prizes — a national awards program for exceptional immigrant integration initiatives — featured panel discussions with the awardees and federal officials and remarks by White House Director of Intergovernmental Affairs Cecilia Muñoz and Assistant Secretary of Education Brenda Dann-Messier.
April 26, 2011
The conference offered law and policy analysis and discussion on cutting-edge immigration issues. Featured panelists included high-ranking government officials, academics, advocates, and other immigration experts.
March 30, 2011
Doris Meissner, Director of the U.S. Immigration Policy Program at MPI, offers her knowledge and expertise regarding border security in this testimony before the Senate Homeland Security and Governmental Affairs Committee.
Video, Audio
March 14, 2011
This discussion focuses on the MPI report, "Executive Action on Immigration: Six Ways to Make the System Work Better," which outlines administrative actions that can be implemented to improve the immigration system.
Video, Audio
January 31, 2011
287(g) programs have surged into the public consciousness in recent years. Now operating in 72 jurisdictions, the 287(g) program authorizes state and local law enforcement officers to screen people for immigration status, issue detainers to hold unauthorized immigrants on immigration violations, and begin the process of their removal from the United States.
Video, Audio
December 7, 2011
A discussion on the gains that young adult immigrants or the U.S.-born children of immigrants have made in education and employment, with speakers: Michael Fix, Jeanne Batalova, Andrew P. Kelly, Raul Gonzalez, and Margie McHugh.
October 6, 2011
This is the latest in NCIIP's language access webinar series exploring the policy and program implementation imperatives for government and community agencies serving Limited English Proficient (LEP) populations.
September 21, 2011
LEP Workers & Access to Workforce Services: Perspectives on Current Barriers to Access and Prospects for Improvements Under WIA Reauthorization
In this webinar, experts discuss barriers immigrant and LEP individuals face in accessing the WIA system, how a revitalized WIA could address these barriers, and the extent to which the current Senate Health, Education, Labor, and Pensions (HELP) Committee's WIA reauthorization proposal addresses these barriers.
August 26, 2011
Through the Prism of National Security: Major Immigration Policy and Program Changes in the Decade since 9/11
With the ten year anniversary of the September 11, 2001 attacks approaching, the Migration Policy Institute held a conference call to discuss the most significant changes that have occurred in the immigration arena in the decade since the attacks.
August 3, 2011
Proactive Engagement: Two Strategies for Providing Language Access in Workforce Development Services
This interactive language access webinar, one in a series offered by the Migration Policy Institute's National Center on Immigrant Integration Policy, examines how New York and Illinois have broken down some of these barriers to proactively engage LEP communities to obtain workforce services.
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December 12, 2013
This panel discussion focuses on the circulation of skilled immigrant professionals and the recognition of foreign qualifications in the United States and Europe.


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"The international dimension of the Grande École programme is without doubt a key element in our identity that sets us apart from other manager training programmes in France."
Marie Pfiffelmann and Babak Mehmanpazir
As (respectively) Director of Studies and Deputy Director of the Grande École programme, Marie Pfiffelmann and Babak Mehmanpazir are the specialist advisors for the school's flagship course. As such, they maintain constant contact with students.
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Family-owned company FM Logistic has become a benchmark reference in logistics services for manufacturers and distributors.
Marie-Laure Schreiber
Director of Corporate Culture, Values and Ethics at FM Logistic, Marie-Laure Schreiber is the business mentor for the Grande École programme's 2013-2016 intake.
Managing creativity
"The STABILO Boss highlighter? Who would have thought of that? Today, two of these pens are sold every second around the world. Highlight that!"
Marc Cronimus
Marc Cronimus, Stabilo's European General Manager, is a graduate of EM Strasbourg. Two good reasons no doubt why he accepted to be business mentor for the Grande École programme's 2012-2015 intake.
A Franco-German Master's degree
"As a leading programme in the School's international academic offering, students following the course spend their first year of study at the ESB Business School in Reutlingen, Germany, and the second year here, at EM Strasbourg."
Enrico Prinz
Course Tutor for the Master's degree in European Management Studies, Enrico Prinz also directs the Business administration module for the Bachelor's degree in International Affairs.
Fostering entrepreneurship
"We bring together the School's activities dedicated to entrepreneurship. We offer a platform for experience-sharing with teaching staff and the professional world, and offer support to the School's project developers, whether student or graduate."
Juliane Santoni
Entrepreneurship Project Manager Juliane Santoni implemented the School's entrepreneurial "hothouse". The result: 'La Ruche' was opened in November 2013.
Career progress
"Whilst it certainly adds to my background as an electronics engineer, this Master's degree course is also a great opportunity for learning, for discovering new challenges as well as opening up mindsets about business and companies."
Christophe Michel
In his second year of studies for a Master's degree in Business Engineering, Christophe Michel enrolled for further professional training to expand his knowledge, strengthen his skills base and get better positioned to move up the career ladder.
Student associations coordinator
"Participating in the school's student associations is a way to add value to your degree. The leeway the School allows us for this means we get to do lots of things in these organisations! And that's all part of the training for a future manager."
Nicolas Drouet
Currently a third-year student in the Grande École programme, Nicolas Drouet has headed up all the course's student associations between 2013 and 2014.
Managing knowledge
"It's the interdisciplinary aspects that lend the Chair its originality. Being attached to a business school, its research will tend to focus on the field of business administration whilst maintaining as wide a range of approaches as possible."
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Jean-Philippe Bootz, Chair of Knowledge Management, focuses his research on issues concerning the creation, optimisation and dissemination of knowledge in companies.
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The kitchen is a room that gets a big makeover when baby arrives. Counter tops that were once clean and empty become cluttered with bottles, baby food jars and other random baby items.
This collection of gear will keep your kitchen pulled together and functioning at full-speed even when you have a toddler pulling at your pant leg and a screaming baby on your hip.
Message central is nice to have in every kitchen; however, it becomes a must when a little one comes along. A place to stick appointment cards for the never-ending year of well-checks, grocery lists, and coupons is a must for any new mom. This beautiful, painted wood cord board by Russell & Mackenna is the perfect solution for all your paper organizing needs in the kitchen.
When Charlie first arrived, leaving the house became at least a 30 minute ordeal. Where are my keys? Where is my cell phone? Do we have a pacifier? What about the camera? Boon's Stash is the perfect place to "stash" all the essentials you need in order to leave the house. I keep mine right by the door and it has truly been a transforming piece of baby gear. A kitchen must!
All bottle racks are not created equal. The first bottle rack we had was like the Leaning Tower of Pisa—a big wobbly mess. I finally just resorted to drying bottles one at a time on a paper towel until I found this cool, sleek rack by Skip Hop. I loved what I saw in the picture, but wondered how it would hold up in person. I was ecstatic to find that it was stable and convenient, and the included bottle brush was a huge plus. This will definitely be my bottle rack of choice with our next little one.
I quickly learned that if I didn't give Charlie something to play with in the kitchen, he would find something to play with himself, so cabinets were slammed, magnets were thrown to the floor, and bibs were strewn. I finally set out on a quest to find a toy that would keep Charlie occupied while I completed my kitchen chores. The wonderful toys by LeapFrog were an obvious first choice and one of their newest toys Cook and Play Potsy is ideal! It offers Charlie the chance to mimic Mommy as he blissfully prepares his own yummy, pretend meals in his very own pot. Perfect!
When it came time for Charlie to try his first meal of solids I was determined that I would personally prepare every single morsel that passed through his tiny lips. Well, I eventually realized that the folks at Earth's Best were great cooks and baby food making just wasn't a hobby that I enjoyed. I did however still need a place to store all those tiny jars. The Sassy Pantry Food Organizer was a perfect fit. Leave it on the counter or tuck it into a cabinet for quick easy meals at your fingertips.
After recently melting several sippy cup tops I decided to revisit the idea of a dishwasher basket. When Charlie was tiny, I had a big, bulky, awkward basket that never seemed to be full and was always taking up valuable dishwasher space. Not so with the Flexible Dishwasher Basket by Munchkin. The folks at Munchkin have really thought this one through, with a skinny mesh basket that tucks in any empty, narrow space in the top rack of the dishwasher. So easy!


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Boulder-area companies prepare for NAHBS
Submitted by David on
A bout 15 years ago, Boulder's Dean Bikes founder John Siegrist said he built an even 50/50 split of custom bikes and stock bikes. Now, Siegrist said, 95 percent of the 150-250 bikes he builds each year are custom made.
In the bike business, run-of-the-mill, status quo rides are no longer cutting it -- and local cycling manufacturers are taking note. Cyclists want something unique, built specifically for their bodies, preferred terrain and style.
"People are tired of getting the same old, 'www-dot-com,' watered down stuff that's all the same," said Chad Melis of Oskar Blues Brewery and REEB Cycles. "With the economy being rough, people are really coming to appreciate something that is handmade by a neighbor, by someone who is a part of their community and doing positive things in their community. We've seen an increased awareness of that across the country, in beer and bikes."
Dean Bikes and Oskar Blues/REEB Cycles are among several local companies attending the ninth annual North American Handmade Bicycle Show, a custom bicycle trade show hosted in Denver this year. Since its inaugural year in 2005, the show has grown from 23 exhibitors and 700 attendees to 170 exhibitors and 8,100 attendees in 2012 -- a sign that custom bikes are becoming more popular in the cycling community.


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The LTE variant of Galaxy S4 powered by Snapdragon 600 quad-core processor has recently received a new Android 4.4.2 KitKat stock firmware update with build number I9505XXUFNC8. The I9505XXUFNC8 KitKat build supports a higher change list number than its previous version, which means it is the latest update available for Galaxy S4.
Update Galaxy S4 LTE (Snapdragon 600) to Official I9505XXUFNC8 Android 4.4.2 KitKat Firmware
April 19, 2014 | 0 comments


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Welcome to the Jungle
THE PARTY More than 900 guests donned their best black-tie attire for one of summer's most anticipated events, which raised more than $1 million. THE SCENE With Chandon sparkling wine in hand, the crowd toured zoo grounds, where animals like the Amur leopard and Eurasian lynx were keeping watch. African lions roamed next to a tented canopy of luxe silent auction items, including a signed Patrick Kane Blackhawks jersey and bright teal Vespa. Calihan Catering's seated, three-course dinner was served underneath HMR Designs' tented pavilion, which was speckled in purple- and blue-tinted lights, with lanterns and huge chandeliers hanging over the dance floor and peacock-feather-printed lampshades as part of the tablescapes. "This event has the reputation of the party of the summer, and tonight will surely be a repeat performance," said Peggy White as she introduced co-chairs Jennifer Caruso, Charlotte Monhart and Vasiliki Weiden. THE HIGHLIGHTS Following last year's surprise performance by the Village People, this year's mystery guest KC and the Sunshine Band took the stage during dinner and had guests flooding the dance floor to hits like "Get Down Tonight" and "That's the Way (I Like It)." And frontman Harry Wayne Casey gave just as much of a stand-up performance as a musical one. "Get a good look at me," said the 62-year-old, "because this is what Justin Timberlake is going to look like in 30 years. And Justin Bieber in 100!" To cap off the night, we stopped by the Forever Yogurt cart for some peanut butter soft serve and snagged a to-go bag of Garrett Popcorn's caramel crisp and cheese corn Chicago Mix. Meaning, of course, that we ended the night with those telling orange fingertips—totally worth it. Photography by Robert Carl, AJ Kane, Aanna Stadem and Violet Dominek


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Tyson with the Thunder
This is why it's so important for our guards to get in the lane. We have the size to get those rebounds if layups are missed, plus it draws the defense in.
Good job moving the ball and getting to the line with shotclock low.....closing this one out
Sent from my LG-P999
Nice timeout both teams were looking hideous lol
Knicks winning a game in which they aren't relying heavily on the 3 plus against a good team. What will people find to hate on now?
Seriously though, this Dallas team is just like their owner, way too much to say. Someone tell Dontay Jones to shut the eff up. Also, Felton, hit a friggin free throw.
Felton needs to shut the hell up. If you can't even hit fts please don't talk trash.
Knicks defense is just too dominant, we hold down position and don't give easy shots to team like we have done in the past.
It's a new team guys, get used to it.
Woodson needs to waste a timeout to discipline there guys cause they've lost focus with 3 minutes left
This game is not over. They better stop playing around out there.


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|Third place Vandals head to WAC Tournament
The University of Idaho volleyball team heads to Las Vegas as the #3 seed for the upcoming Western Athletic Conference Tournament. The Vandals will face #6 seed Boise State Monday (Nov. 23) at the Orleans Arena at 5 p.m.
Idaho finished the regular season with a 15-14 overall record and was third place in the WAC standings at 11-5.
Idaho and Boise State split the season series with each team winning on its home court. The Vandals defeated the Broncos 3-0 at Moscow in the final match of the regular season Thursday (Nov. 19).
For tournament information, click here.
For live stats for all tournament matches, click here.


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Finding a LumpThe sun streamed into her hotel room as she stood before the mirror. Darryle Pollack brushed her hair and felt her heart clench like a fist as she watched the long red curls come out in great handfuls. She wondered how much more of this she could take."Losing my hair was worse than losing my breasts," she says. "I had waist-length, wavy, gorgeous thick hair. I loved my hair." Pollack had made some big changes over the years to put her life in order. She'd quit her job as a television reporter in Los Angeles. She'd divorced and remarried and endured a night of terror during the earthquake of 1994, running barefoot over broken glass to rescue her two children. The newly combined family moved to a house in Carmel. After a difficult transition, things had settled down at last. She was doing marketing for her new husband's health-supplement distribution company. Life was good.Then, one bright Friday morning just before the Fourth of July, Pollack was taking a shower, thinking about the busy weekend ahead, her son's 7th birthday party, and there it was. Just like that: a lumpy mass in her right breast, slick with soap beneath her index finger. Something inside her that didn't belong. Where had it come from? How long had it been there? She'd had a mammogram only eight months before. She went to work, thinking, well, it's probably nothing, but it needs checking. She called the only mammography clinic she found in the phone book. To her surprise, they wouldn't see her without a doctor's order. It struck her as ridiculous. She'd moved to Carmel less than a year ago, and didn't have a doctor yet. She needed someone to look at this — now. Pollack went to a neighbor who was an orthopedic surgeon, and he ordered the test. Her son's party didn't give her much chance to worry that weekend. She went to the clinic Monday and thought it odd that they asked for a second film. Still, she felt no real sense of alarm. Only later that night, when she saw her neighbor standing at her front door with the film in his hand did she feel the fear, liquid and trembling, settle in her stomach.Misdiagnosis? They sat on the couch in the family room, and he spread out the films. He said he didn't know much about breast cancer, but if she were his wife, he'd get her to a surgeon. "My immediate feeling was: They made a mistake again." Again meaning her mother, who died of cancer after a malignant melanoma was misdiagnosed. Two days after her mammogram, Pollack was on a plane to Los Angeles, having arranged a surgical biopsy through her former doctor.She found herself sitting on an operating table in the white light of a cold steel room wearing a hospital gown, "and I really didn't have a good feeling about the surgeon," she says. "It was a gut feeling, my personal reaction to him." Pollack didn't like the way he spoke to her husband before addressing her. In less than 48 hours, she felt her body, her autonomy, had been taken from her. Nothing catastrophic happened — not a very good scar, but that wouldn't matter soon: The biopsy was positive; she needed a mastectomy. Still, she resolved that it would be the last time she'd passively allow medical professionals she didn't know or trust to dictate what happened to her. "I'm a good girl," says Pollack, who is now 55. "I always follow the rules." But now there was too much at stake. And it felt good deciding to take charge. It felt right. Finding another surgeon was simple compared with what lay ahead. There were several types of cancer in the same breast, and the disease was clawing into her lymph nodes. Soon she had an oncologist (whom she liked and trusted) telling her what he thought she should do by way of chemotherapy, recommending a slightly higher than normal dose. But there was a debate going on at the time about whether an even higher amount was better, and neither Pollack nor her oncologist could be sure how much would be enough."Almost immediately, I had to become an expert on high-dose chemotherapy," Pollack says. She began calling all over the country to researchers at Duke University, UCLA, Sloan-Kettering, to learn more. "Basically, this was my full-time job."She visited a prominent oncologist at UCLA who looked at her file and recommended that she quickly enter a high-dose program. "He scared me so much. I just didn't like his attitude. He was very condescending." When the doctor left the room, Pollack turned to her husband and said, "I hate this place. I hate this guy. This is bad for me." She remembered the feeling she'd had in the operating room before her biopsy. They didn't even wait for the doctor to return. They just walked out. She had never done anything like that before. "The worst part for me was feeling the burden of making a decision about my treatment when I didn't know anything," she says. "There was always something new to read, another person I could talk to. I just didn't know how to let go of whatever decision I made, and I didn't know how to reach a final decision. Some people can just say, 'Doctor, I'm in your hands.' And I just wasn't that person."She plunged into the literature, worked the phones, even flew around the country to get the best advice — all in a matter of a few weeks. In the end, she settled on the course that the first oncologist had recommended. But her experience of making that decision was far different from what it would have been if she'd simply taken the advice without question. Playing Doctor During her research, Pollack had read that a certain kind of woman — one like her, who was fairly young and still fertile with an estrogen-positive tumor — was at greater risk for a recurrence of the cancer. So she decided to have her ovaries removed. When she asked her doctor at Cedars-Sinai for help, he told her he couldn't let her do that. But if there was even a chance that the estrogen produced by her ovaries was decreasing her chances of survival, she wanted them out. She'd already had two children. And those children needed her alive.Pollack spent days agonizing, meditating, trying to make the decision. She got a second opinion, and it was the same: Don't do it. In the end, she went to the doctor who had arranged the initial biopsy for her. He'd delivered her babies. She trusted him. When she explained what she wanted, he said, "I really think it's overkill, but if you think that it's important for you, I'll do it." Less than a week later, she found herself standing in front of that mirror, brushing the long red hair right off her head and onto the floor. And as she stood there looking at herself — her new self — she said, "Something switched in me at that point. I became my doctor. There were no illusions anymore. I was the doctor."Pollack had no idea that, eight years later, she'd still be her own doctor, nor that her odyssey would come to exemplify two schools of thought — one, a growing movement to ensure that medical decisions are based on the best possible scientific evidence, and another, recognizing the importance of trusting one's own instincts about healing.Will It Work? Before my first wife, Carolyn, had breast cancer, she'd known only the traditional experience of Western medicine, in which she played the role of a supplicant. She'd go to the doctor's office, and it would be crowded. She'd wait. Eventually, the doctor would see her briefly and pronounce what she was to do — or what would be done to her — and that, more or less, was that.When she was diagnosed in 1989, we stopped being passive and became a team. I had the benefit of some scientific training (meaning I understood doctor-speak), and she had the benefit of a strong personality and of being wicked smart. We questioned everything the doctors said. One of the things we always asked when they suggested a treatment of one kind or another — surgical, pharmaceutical, therapeutic — was, "How do you know this is going to work?" Like most people, we had always assumed that there was hard scientific evidence and rigorous testing behind any treatment a doctor would order. But there isn't always such a solid rationale behind a doctor's orders. Tradition, educated guesswork, or "That's what my mentor told me" are often closer to the truth. Doctors may find the evidence confusing or even contradictory. This state of affairs leaves patients like Carolyn and Darryle groping for answers when they desperately need to figure out what's best for them. Doctors vs. Scientists Over the past several decades, a move toward a more organized, integrated approach to medicine has begun to take shape. In the '70s, three British obstetricians began a groundbreaking and monumental project that would be published in 1989, titled The Oxford Database of Perinatal Trials. Using a volunteer workforce to catalog decades of research, it showed which of the many types of care were unequivocally effective during pregnancy and childbirth. Electronically searchable, it gave clinicians, for the first time, the ability to practice what is now being called evidence-based medicine. That effort led in 1993 to the establishment of the Cochrane Collaboration, a vast, multinational project designed to bring the same rigorous standard of evidence to every field of healthcare.The ramifications of such a database for patients are enormous. But the effort is not without controversy. In the fall of 2001, for example, a Cochrane analysis suggested that the available evidence from clinical trials did not show that regular mammograms save lives. "The whole flap about mammography is really a culture clash," says Kay Dickersin, director of the U.S. Cochrane Center and an epidemiologist at Brown University, whose specialties include women's health and issues of bias in scientific research. "It's public-health scientists versus doctors. The scientists rely on data grouped together from populations, such as the percent of women who've had mammograms and survived, while doctors and patients are most interested in how the individual patient fares. And it's very hard for those two cultures to meet, because the individual might say, 'Look, I'll take any chance to have this detected early, and I don't care if your data show that earlier isn't necessarily better.'" That, of course, was the dilemma Darryle Pollack faced. On the one hand, she wanted to know what treatment had been shown to work; on the other hand, she wanted to be in collaboration with someone who respected her right to choose — even when the evidence, and her subsequent treatment choices, seemed to be in conflict. Evidence"Evidence-based medicine is not just practicing on the basis of the evidence," Kay Dickersin insists. She uses the example of tamoxifen, a drug that has been shown to increase the chances of survival for most breast-cancer patients, to explain this seemingly contradictory statement. Logic might dictate that, because the evidence says it works, it's right for everyone. But that would be "cookbook medicine," a phrase used in criticizing the movement by people who fear that once a course of treatment is shown to be effective, everyone will be expected to accept it without question. Evidence, says Dickersin, is simply one element of what she prefers to call "evidence-based healthcare." "Other important components are patient values, physician values, physician knowledge and experience." In other words, a collaboration in which the patient and the doctor both have access to the best clinical evidence for what works and what doesn't, and then decide together what course to take.In fact, Dickersin, now 53, was diagnosed with breast cancer herself in 1986 and was told to take tamoxifen — and refused. Her decision was based on a knowledge of the evidence as well as a knowledge of herself. "At some point I did seriously consider it," she says. "I elected not to do it because … Ahh …" She paused and sighed, as if this were difficult for her to admit. "I don't like to take pills, so I just thought I was likely to become a noncomplier at some point because I did not view myself as, nor did I want to view myself as, a sick person. And I didn't want to go into menopause at 34. Other women may have the same feelings but not make the same decisions. I'm a risk-taker in some situations, and this was one of them." She had come to the heart of the matter: When taking care of your own health, you have to be human and you have to be yourself. A good doctor will respect your feelings and allow you to walk your own path with dignity. Dickersin had such a physician: "My doctor didn't say, 'You're crazy.'" Dickersin had three types of cancer in one breast, which were treated first by lumpectomy and then mastectomy a few weeks later. Her doctor told her that she had the option of "watchful waiting" with the other breast. But Dickersin knew that one of those three types of cancer had a tendency to spread. "And I mean, I was really scared to wait." In the end, she said, "Okay, I've had it. I'm not going to have biopsies forever. I'm too young." Though it showed no sign of cancer, she had her other breast removed.Evidence-based healthcare, then, contains this seeming paradox. Having scientific evidence is, of course, better than not having it. But Kay Dickersin would argue that evidence encompasses more than, say, mortality rates. Psychological factors, such as the debilitating stress from repeated treatments and health scares, can be just as crucial when making a decision. Knowing the evidence is good. Knowing yourself is better. Knowing both is best. Demanding Change Like Kay Dickersin, who is now free of cancer, Darryle Pollack eventually decided to have her other breast removed as a precaution. Both women sought treatments not recommended by their physicians, because these were the paths they felt most confident taking. Being your own doctor can be hard at a time of extreme vulnerability. But believing that you are in control can actually be good for your health. Robert Sapolsky, a MacArthur Fellow famed for his research on stress, points to studies in which two groups were exposed to the same stressful stimulus. One group was led to believe it had some control over the stimulus — a lever to pull, a puzzle to solve — while the other had nothing to do. The stress levels in the first group were far lower, despite the fact that their actions had no real effect. The point was, they were doing something. Dickersin wears a button that shows the yin-yang symbol. On one side of the symbol it says, "Trust me, I'm a doctor." On the other side it says, "Ask me about the evidence." She believes that if the practice of healthcare in this nation is going to change, it will be because people like Pollack demand a better quality of evidence and more control. "I do think the consumer can know enough to understand evidence-based healthcare. And that there's good research and bad research. And to [learn to] ask the doctor questions." This spring she is meeting with consumer groups, her Cochrane collaborators from abroad, and others to design a course that will teach people how to apply evidence-based healthcare principles on their own. When It's OverWomen who have had breast cancer often discover that when the surgery is over, the chemotherapy done, the radiation finished, they face an unsettling void. This is essentially what Pollack encountered when her radiation was finished. "They tell you basically when you're done, well, you can take tamoxifen, and good luck; let's hope you don't have a recurrence, bye-bye."She continued her intensive research, at last finding doctors willing to pick up where the others left off: Mark Renneker, a physician in San Francisco who employs a "patient-directed" approach, and Keith Block, whose oncology practice in Chicago combines traditional therapies with diet, exercise, and other techniques. In addition, the broad net Pollack had cast brought her news of a long-term trial being conducted at Finch University of Health Sciences/The Chicago Medical School (now known as Rosalind Franklin University of Medicine and Science). A doctor named Georg Springer, heir to the German publishing giant Springer-Verlag, was motivated to use his own money to develop a vaccine when his wife contracted breast cancer. He had discovered certain antigens in cancer tissues that don't occur in healthy tissue. By developing a vaccine to produce antibodies against those antigens, he believed, he could stimulate the patient's immune system to prevent a recurrence of breast cancer. That was the aim of the clinical trials he began in 1974 at two locations in Illinois. According to a 1995 report of results, of 19 original patients, all survived for at least five years, and 11 had survived for between 10 and 18 years. The number of women enrolled in the study eventually grew to more than 100, and the U.S. Food and Drug Administration granted the vaccine approval as a Compassionate Investigational New Drug. Still, the trials remained controversial because there was no control group against which to measure results. In other words, the research would not meet the Cochrane standards. But when Pollack read about the trials, she believed that the vaccine might help her survive. Her main concern was that she'd have to fly to Chicago every few weeks to receive the vaccine for the rest of her life. "I really had to think about that, because that was a big commitment." But she read the consent form, and saw that it promised to keep her on the vaccine "ad infinitum." She decided that her own commitment should match theirs. "I thought, if I want to live, what's the big deal? I go to Chicago." She was accepted into the program in May 1996. Pollack's course was set. The intense days and nights of search and research were over. She made changes in her life involving diet and exercise, and felt at last that she had her health back under control. And indeed, it seemed to be for the next seven years. The women in the trial, who were scattered across the country, formed a coalition to keep in touch. For the first time in years, cancer didn't occupy Pollack's every waking thought. She returned to her work and family and made regular trips to Chicago for the vaccine. Her health was good.Then Pollack began to hear rumors that the medical school was not really supporting the vaccine. After Springer died in 1998, the school began laying off the staff of Springer's lab, and by 2003, almost everyone was gone. By the fall, she heard that the program might be cancelled. "I didn't believe it," she said. "There'd been rumors before." But in February 2004, each patient received a letter from the medical school saying that the trial had been cancelled. After three decades, the late Dr. Springer's work was over.Now Pollack and her medical consultant Mark Renneker began trying to figure out how she could get the vaccine. "I'll never know whether or not the vaccine is what's keeping me alive," she says. "But I just want to keep doing it, because I believe it is." Her doctor found a way to have the vaccine made abroad. But she began thinking about the other women. What would they do? Not all of them would be able to afford to go abroad and have the vaccine made. She also felt that this was one of the few protocols that could fill the vacuum left when women with breast cancer finish their chemotherapy and radiation. She decided at that moment to try to get the vaccine back, not just for herself, not just for her group, but for others, as well.Legal ActionThere are some complex issues tied up in Pollack's decision, which was not strictly scientific, not strictly rational, but grew out of a blend of rational and emotional motives. Recent neuroscience has shown that so-called "gut feelings" are real elements of our ability to make good decisions. We can take in large amounts of information — too large to remain in consciousness — and use it to reach valid conclusions, all outside the normal process we call reason. Pollack couldn't prove that the vaccine was effective. But the medical school had promised to provide it indefinitely and, perhaps more important, the vaccine gave those women an answer to the question: What do I do for the rest of my life? In her gut, she knew that she was onto something with the Springer vaccine. She felt that the school officials would listen to her and keep the trials going long enough to let the women find an alternative. Being a TV reporter, she could also envision a group of 50 breast-cancer patients marching with signs in front of the medical school, and thought surely the school wouldn't want that. When the school remained unresponsive, Pollack found a lawyer in Chicago, Robert Cummins, who was willing to negotiate on behalf of the women. When I spoke to him, Cummins said, "When I first heard the story, it seemed incomprehensible. No reputable medical institution could possibly shut the door on these women."Cummins set up a meeting with school officials; they were very cordial, and gave Pollack the impression that they'd strongly consider her proposal. She left the meeting convinced that she'd get her next dose of the vaccine, which was already overdue, within weeks, since there was an unused supply on the shelf. Then she learned that the school had already notified the FDA that they were closing down the program. It was as if Georg Springer and his vaccine had never existed. Going to Court In the summer of 2004, Pollack and Cummins sued the Chicago Medical School (CMS) on behalf of the 50 women in the Springer trial for the right to take over the research and whatever remained of the roughly $18 million Springer had left to support the program. At the time of the suit, Patrick Coffey, a lawyer for CMS, reiterated what numerous doctors and scientists had said of the trials. He told a news service, "There was an absence of information that allowed us to say this was valid science and that it was providing a benefit to those human beings involved." In court that fall, Michael Schrift, a psychiatrist and head of the school's review board, was pressed repeatedly by Cummins about why CMS had shut the research down. Schrift testified that the school had acted properly in canceling the program, and that it did so because the vaccine had not proven effective, nor could its safety be adequately determined. The women, he suggested, had placed false hope in the vaccine, believing "it was treatment, where in fact it was research."Wayne Jonas, MD, director of the Samueli Institute, a nonprofit medical research organization, had his own wife enrolled in the Springer trial, and testified for the plaintiffs. "The science is not perfect, there's no question about it," he says now. "But this is the longest human breast-cancer vaccine trial in the country, and probably in the world." And, according to Jonas, "An independent comparison [found] the overall survival rate for women on the vaccine was 30 percent better than for those who were not." The case settled quickly. "The University believes that the prior decision of its Institutional Review Board regarding the T/tn [Springer] vaccine study was correct," said Robert Vogt, an attorney for the school, in a press release issued at the time. But the school agreed to pay the cost of pursuing FDA approval at another institution, and to turn over all research materials, including the vaccine, to the women, in addition to an undisclosed amount of money from Springer's bequest. (School officials declined to comment directly for this article; their press representatives referred instead to the aforementioned press release.) The women and their lawyer, Cummins, are now seeking a new home for the Springer vaccine trials. But Pollack's long fight left her feeling as if she had so much more she could do for others. "It sounds really hokey," she told me, "but I felt like I've been put in this position where I can do something that could make a difference." She decided to start her own foundation, with the support of Springer's daughter Julia Tolkan, who watched her mother die of breast cancer, to continue and broaden his work and support other research. The idea is in its early stages and she isn't sure what it will encompass, but she wants to give women a stronghold from which to defend the right to control their own healthcare. "I'm not a religious person," Pollack told me. "I'm not even particularly spiritual. But I feel like it was my turn to do something." It was a turning point in her survival story. In her first year after diagnosis, she had to stay in the moment, focused on her physical survival. In her fight to get the vaccine trials continued, she was battling for her group. That victory was behind her. Now she looked forward to a new way to struggle meaningfully for something larger than herself. Because the struggle itself is important. Too much stress can hurt you, but too little can, as well. Even animals know this. The fruit gained through struggle is always the sweetest. In laboratory experiments, they'll choose food they have to work for over what's freely given. The last time I spoke with Darryle Pollack was at her art studio in Carmel. When she was finishing her chemotherapy, facing the unknown, she began painting ceramics in a small shop at a mall near her home. "In school I was always a whiz at history and English, but when it came to art, I was absolutely remedial," she explained. But somehow the clay and glazes just spoke to her as she sat at a workbench with the sunlight streaming in through a big picture window. As she worked over the years, she inevitably broke a few pieces. She saved the fragments and started making mosaics. She liked doing that so much that she began painting ceramic tiles specifically to break them. She rented a vacant shop in the mall and turned it into an art studio. We walked over from the ceramics shop, and she showed me her work — large, impressive pieces with dramatic designs. There were mirrors, tables, and bowls decorated with tile fragments and often with words, such as "lucky," "hope" and "happiness" hidden in the designs. She locked up her studio, and we walked to lunch along the tree-lined, sunlit lanes. I asked her what her artwork meant to her. Although it was clearly marketable, she said she didn't want to sell it in galleries. "I think I like it because it tells so much about my story," she said. "Or anyone's life, for that matter. Life smashes things to bits, and you put it back together and make something beautiful with the pieces." Healthcare Data on Demand?Researching an illness and evaluating your choices can be an overwhelming task. The Cochrane Collaboration, an international nonprofit organization, is reviewing all available medical evidence and working to make that information available to the consumer. What is it? More than 11,000 contributors worldwide — healthcare professionals, researchers, consumer volunteers, and others — comb through medical literature as far back as World War II in more than 50 subject areas ranging from lung cancer to strokes to palliative care. The data is then analyzed to see which treatments are truly effective. More than 2,000 studies are complete (with more in the works), and will be updated as new evidence accumulates. Who can use it: Abstracts are available free online, but to view the full reports, individuals must pay $265 a year for a Cochrane Library subscription (single report views start at $25). Citizens of several countries, including England and Australia, can use the database without charge because their governments subscribe. Most academic medical institutions in America subscribe; the state of Wyoming has purchased a subscription for its residents. Where to find it: Online, www.cochrane.org.
When Illness Strikes: How to Get the Best Medical Care
We can now research our illnesses like never before. But whom do you trust, and where do you stop? Two women, one a cancer patient who took charge of her own drug research, the other a scientist who faced her own health crisis, show how they found their way
By Laurence Gonzales


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hepatitis b vaccine - injection, Engerix-B, Recombivax HB
GENERIC NAME: HEPATITIS B VACCINE - INJECTION (hep-uh-TIE-tuss B)
BRAND NAME(S): Engerix-B, Recombivax HB
Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
USES: This medication is used to help prevent infection from the hepatitis B virus. Hepatitis B infection can cause serious problems including liver failure, persistent hepatitis B infection, cirrhosis, and liver cancer. Preventing infection can prevent these problems.Hepatitis B vaccine is a genetically engineered (man-made in the laboratory) piece of the virus. It does not contain live virus, so you cannot get hepatitis from the vaccine. This vaccine works by helping the body produce immunity (through antibody production) that will prevent you from getting infection from hepatitis B virus. Hepatitis B vaccine does not protect you from other virus infections (such as HIV virus which causes AIDS; hepatitis A, hepatitis C or hepatitis E; HPV virus which causes genital warts and other problems).The vaccine is recommended for people of all ages, especially those at an increased risk of getting the infection. Those at an increased risk include health care personnel, laboratory workers who handle blood and patient specimens, police, fire and emergency medical personnel who give first aid treatment, hemophiliacs, dialysis patients, people who live with or spend much time with people with persistent hepatitis B infections, people with multiple sex partners, men who have sex with men, sex workers, injection drug abusers, and people traveling to high-risk areas.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Need help identifying pills and medications?
Back to Medications Index


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I saw this memo on the official whitehouse.gov website the other day, but I was traveling and never had a chance to post it. I figured it would be too late by now, yet I am still not seeing it being widely discussed. It implies that the Obama Administration may be very worried about the truth getting out about all of their crimes, potentially via leaks from high places. Read it for yourself, but the language is pretty clear. Here are some excerpts:
This Presidential Memorandum transmits the National Insider Threat Policy and Minimum Standards for Executive Branch Insider Threat Programs (Minimum Standards) to provide direction and guidance to promote the development of effective insider threat programs within departments and agencies to deter, detect, and mitigate actions by employees who may represent a threat to national security.
The resulting insider threat capabilities will strengthen the protection of classified information across the executive branch and reinforce our defenses against both adversaries and insiders who misuse their access and endanger our national security.
Oh and this came out the day before Thanksgiving. How cute. As someone said on twitter today, if telling the truth endangers "national security," then we are doing national security wrong.
Full memo here, please read it is very short.
In Liberty,


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Effective, easy-to-use ear miticide drops kill ear mites and ear ticks to help your kitten's or cat's ears stay healthy and comfortable. Ear-Rite Miticide for Cats & Kittens also contains soothing aloe vera and is gentle enough to use in kittens as young as 12 weeks old. Ear-Rite Miticide for Cats & Kittens also helps in the removal of ear wax from your cat's ears. Convenient dropper bottle makes application easy.
Shop all cat ear care products.
Please click on "More Information" for active ingredients, usage instructions, and additional product details.


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Turkish Airlines will open its "Lounge" for Business Class passengers, available after international arrivals in Istanbul.
Turkish Airlines continues to enhance the travel experience for its international Business Class passengers. Turkish Airlines inaugurated its new "Istanbul Arrival Lounge" in a ceremony, designed to provide a space where inbound guests may refresh themselves before exiting the Ataturk Airport. This is the most recent innovation directed at making Business Class travel on Turkish Airlines a uniquely pleasurable experience.
The lounge, which is 250m2, has a capacity of 38 seats and provides a comfortable ambience for passengers to relax and refresh after their flight.
The Lounge offers passengers shower facilities, areas for changing clothes and staff dedicated to ironing clothing items if desired. There are also delicious treats prepared by Turkish DO & CO—all designed to ready passengers for the tasks that await them upon leaving the airport. This service is especially valuable to guests arriving in the early morning when hotel rooms are generally not yet available for check-in.
Also available are daily local and foreign newspapers and magazines, a full wireless internet connection, media walls and charging points for passengers' electronic devices.
The lounge will be open every day to receive arriving passengers from 05:00 - 12:30 (local time) and will be closed each day at 13:00 (local time).
Important details for using the Istanbul Arrival Lounge;
- Only Business Class passengers and Economy or Comfort Class passengers having Elite Plus membership will be able to use the lounge on arrival in Istanbul following their international flights.
- Star Gold members and other Miles & Smiles members--except Elite Plus members - will not be eligible to use the Lounge. Additionally, eligible passengers will not be permitted to bring guests.
Turkish Airlines, Inc.
Media Relations
20.09.2013 Updated


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