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|By Business Wire
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|October 17, 2012 07:37 AM EDT
SPEC's High-Performance Group (SPEC/HPG) has released an updated benchmark for measuring performance using applications based on the OpenMP 3.1 standard for shared-memory parallel processing. The benchmark, called SPEC OMP2012, includes an optional metric for measuring energy consumption.
SPEC members who participated in SPEC OMP2012 development include AMD, Argonne National Laboratory, IBM, Fujitsu, Intel, Oracle, PGI, SGI, Indiana University and Technische Universität Dresden.
Vital tool for HPC community
SPEC OMP2012 replaces SPEC OMP2001, a benchmark that was embraced by the high-performance computing (HPC) community. Nearly 400 results submissions using the benchmark have been published on the SPEC website.
"SPEC OMP2001 proved to be a very useful tool for measuring performance and scalability of parallel computing systems," says Kalyan Kumaran, SPEC/HPG chair. "The new benchmark reflects the industry's hardware and software advances, the latest directives and standards from the OpenMP Architectural Review Board (ARB), and the increasing demand for measuring energy consumption."
Application-based benchmarking
SPEC OMP2012 includes 14 scientific and engineering application codes, covering everything from computational fluid dynamics (CFD) to molecular modeling to image manipulation. The optional energy consumption measurements are based on the SPEC Power and Performance Benchmark Methodology, which provides details on how to integrate a power metric into standardized benchmarks.
Application-based performance tests running under SPEC OMP2012 require 32 GB of memory. A complete series of benchmark runs required for a SPEC submission takes more than 72 hours on an eight-core, 2.7-GHz reference machine.
"We're delighted that SPEC has refreshed its OpenMP-based benchmark suite to reflect our latest standard," says Michael Wong, CEO of the OpenMP ARB. "I expect that SPEC OMP2012 will be used throughout the world to evaluate and advance the performance of systems running OpenMP-based applications."
Available immediately from SPEC
The updated benchmark is available immediately from SPEC for $800 for new customers, $250 for upgrades from SPEC OMP2001, and $250 for qualified non-profit organizations and accredited educational institutions. For more information, visit http://www.spec.org/hpg/omp2012 or inquire through email at [email protected].
About SPEC/HPG
SPEC's High-Performance Group (SPEC/HPG) produces industry-standard benchmarks for comparing high-performance computer systems and accompanying software. Its membership comprises more than 30 leading HPC vendors, national laboratories and universities from around the world.
About SPEC
The Standard Performance Evaluation Corp. (SPEC) is a non-profit organization that establishes, maintains and endorses standardized benchmarks to evaluate performance for the newest generation of computing systems. Its membership comprises more than 130 leading computer hardware and software vendors, educational institutions, research organizations, and government agencies worldwide.
Company, product and service names mentioned herein may be the trademarks of their respective owners.
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January 11, 2011
Ramani Narayan, University Distinguished Professor of chemical engineering and materials science, has received the prestigious Award of Merit from ASTM International. Formerly known as the American Society for Testing and Materials, ASTM is a globally recognized leader in the development and delivery of international voluntary consensus standards.
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Marriage Equality
As of June 26, 2015:
To date: 23 countries have legalized same-sex marriage: Argentina (2010), Belgium (2003), Brazil (2013), Canada (nationwide 2005), Denmark (2012), Finland (eff. 2017) France (2013), Greenland (Oct. 2015) Iceland (2010), Ireland (eff. TBD) Luxembourg (2015), Mexico (nationwide, eff. TBD) Netherlands (2001), New Zealand (2013), Norway (2009), Portugal (2010), Slovenia (eff. TBD), South Africa (2006), Spain (2005), Sweden (2009), Uruguay (2013), Untied Kingdom (England and Wales, 2014), United States and territories (nationwide 2015).
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Ministers seek to invalidate state law on marriage licensesFriday, January 22, 2016A lawsuit filed Thursday notes Tennessee law requires marriage license applicants to be male and female.
Senator seeks protections for same-sex marriage objectorsThursday, January 21, 2016A Georgia lawmaker says religious adoption agencies, schools and other nonprofits should be able to refuse service to same-sex couples.
This news site was being accosted by a vicious antigay troll. Their response is perfect.Thursday, January 21, 2016"Where was the caution or warning for this image?"
Sponsor of anti-gay marriage bill is undaunted by $8.5B costWednesday, January 20, 2016The lawmaker whose bill would bar Tennessee from following the gay marriage ruling doesn't care about the $8.5 billion loss.
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Britain's Anglican Church avoids split over gay rightsSaturday, January 16, 2016Anglican leaders have overwhelmingly decided to stay together at a summit aimed at preventing a split in their fellowship over homosexuality
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We were in St. Louis for 2 1/2 days- mainly to see the Cardinals & tour the stadium- but found there is a surprising amount to do- especially things for kids
If you are there for more than a night - I would stay in Forest Park. There's a lot of restaurants, bars, and many activities are out there. We stayed near the Arch & the Stadium at the Robert Mayfair Hotel. It was awful and unsafe. It's inexpensive but I do not recommend it. I've posted a separate review on that. You really need a car as things are very spread out- especially in Forest Park.
Things to do:
Arch- if you don't do the movie- the whole experience is very quick- you are out in about an hour- the pod elevator that takes you up is very small- and the windows are small when you get up there- you really only spend about 10 minutes up there.
Stadium- we did a tour there which was good and you have to see a game there
City Museum- amazing museum with multilevel slides- great for all ages- even teenagers, on nice days there's an outdoor park on the roof that's supposed to be great
We tried to get to Candy Crown Kitchen- an old soda shop- but there was a long wait on the weekend- try on a weekday
If your child is a train lover- go to the Museum of Transportation in the suburbs. There's a train ride for the kids & many engines for them to climb on & a car exhibit- if you have time- they even have classes for small kids
In Forest Park
St. Louis Zoo was great- it's free- there's a petting zoo you can go to (we didn't have time for) but the train ride & carousel was a huge hit with our two year old
New Cathedral- A beautiful church with great detail- looks like it's out of Europe
We stopped in the Missouri Museum to see an exhibit on the World's Fair and stopped over at the site (the pavilion strangely was built after the World's Fair)
Turtle Park- giant turtle sculptures- fun for the kids to climb on
Jewel Box- the conservatory- was a beautiful little place to pop in and see
We ate at O'Connell's Pub- which we heard had the best burger- but it was just average
Pi - deep dish pizza- Obama had this flown into the White House for a party- go early as there are waits- really great pizza
Ted Dawe's- ice cream custard- good- but nothing to go out of your way for
We had a busy trip but most stops were pretty brief so we were able to see a lot.
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St Louis- with young kids
We were in St. Louis for 2 1/2 days- mainly to see the Cardinals & tour the stadium- but found there is a surprising amount to do- especially things for kids
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Thanks for giving St. Louis such a positive review, I'm glad you had a good time. Sorry the Mayfair wasn't good, I always hesitate to recommend hotels here since I never stay in them. I will look for your other report to read about the issues you had.
Did you see a winning Cards game?
Just few comments if someone uses this thread to plan a trip to St Louis:
Forest Park is a PARK, there are no hotels located within the park.
Turtle Park was designed by Bob Cassilly, who designed and operates the City Museum. There are other Cassilly sculptures in different cities, I know there are nice Hippos in a playground in Riverside Park in NYC.
Interesting article about City Museum in Wall Street Journal on May 1st. http://online.wsj.com/article/SB10001424052702304159304575183463721620890.html
It's the Missouri History Museum, also free in Forest Park.
Ted Drewes, a St. Louis institution. http://www.teddrewes.com/Drewes.asp
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Great trip report julieod. St. Louis is my hometown and I have many fond memories of summers filled with Cardinals baseball, the zoo, and Ted Drewes.
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Nice report - it is nice to read about one's hometown!!
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Science City is also FREE - The Magic HOuse did offer FREE fridays. Grants Farm is free. You can tour the brewery for FREE - kids will even like this -
the Arch - not free but amazing!!
The Hill is the place for italian food
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Author and Publisher - Catholic Online
St. Theophanes Abbot and Confessor MARCH 12 A.D. 818 His father, who was governor of the isles of the Archipelago, died when he was only three years old, and left him heir to a very great estate, under the guardianship of the Iconoclast emperor, Constantine Copronymus. Amidst the dangers of such an education, a faithful pious servant instilled into his tender mind the most generous sentiments of virtue and religion. Being arrived at man's estate, he was compelled by his friends to take a wife; but on the day of his marriage, he spoke in so moving a manner to his consort on the shortness and uncertainty of this life, that they made a mutual vow of perpetual chastity. She afterwards became a nun, and he for his part built two monasteries in Mysia one of which, called Megal-Agre, near the Propontis, he governed himself. He lived, as it were, dead to the world and the flesh, in the greatest purity of life, and in the exercises of continual mortification and prayer. In 787, he assisted at the second council of Nice, where all admired to see one, whom they had formerly known in so much worldly grandeur, now so meanly clad, so modest, and so full of self-contempt as he appeared to be. He never laid aside his hair shirt; his bed was a mat, and his pillow a stone; his sustenance was hard coarse bread and water. At fifty years of age, he began to be grievously afflicted with the stone and nephritic colic; but bore with cheerfulness the most excruciating pains of his distemper. The emperor Leo, the Armenian, in 814, renewed the persecution against the church, and abolished the use of holy images, which had been restored under Constantine and Irene. Knowing the great reputation and authority of Theophanes, he endeavored to gain him by civilities and crafty letters. The saint discovered the hook concealed under his alluring baits, which did not, however, hinder him from obeying the emperor's summons to Constantinople, though at that time under a violent: fit of the stone; which distemper, for the remaining part of his life, allowed him very short intervals of ease. The emperor sent him this message. "From your mild and obliging disposition, I flatter myself you are come to confirm my sentiments on the point in question with your suffrage, it your readiest way for obtaining my favor, and with that the greatest riches and honors for yourself, your monastery, and relations, which it is in the power of an emperor to bestow. But if you refuse to comply with my desires in this affair, you will incur my highest displeasure, and draw misery and disgrace on yourself and friends." The holy man returned for answer: "Being now far advanced in years, and much broken with pains and infirmities, I have neither relish nor inclination for any of these things which I despised for Christ's sake in my youth, when I was in a condition to enjoy the world. As to my monastery and my friends, I recommend them to God. If you think to frighten me into a compliance by your threats, as a child is awed by the rod, you only lose your labor. For though unable to walk, and subject to many other corporeal infirmities, I trust in Christ that he will enable me to undergo, in defense of his cause, the sharpest tortures you can inflict on my weak body." The emperor employed several persons to endeavor to overcome his resolution, but in vain: so seeing himself vanquished by his constancy, he confined him two years in a close stinking dungeon, where he suffered much from his distemper and want of necessaries. He was also cruelly scourged. having received three hundred stripes. In 818, he was removed out of his dungeon, and banished into the isle of Samothracia, where he died in seventeen days after his arrival, on the 12th of March. His relics were honored by many miraculous cures. He has left us his Chronographia, or short history from the year 824, the first of Dioclesian, where George Syncellus left off, to the year 813. His imprisonment did not allow him leisure to polish the style.
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Barbara lived in the 4th century and brought up as a heathen. A tyrannical father, Dioscorus, had kept her jealously secluded in a lonely tower which he had built for that purpose. Here, in her forced solitude, she gave herself to prayer and study, and contrived to ... continue reading
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Farr 30 World Championship 2014 preview
by Farr 30 Class Associationn on 25 Feb 2014
Photo of 2013 event - Groovederci won - Farr 30 World Championship 2014 © Meredith Block/Farr 30 worlds
Farr 30 World Championship 2014 will be hosted by the spectacular city of Copenhagen, Denmark and the Royal Danish Yacht Club (KDY) from August 24 to 30. This storied event returns to Europe after a successful 2012 World Championship sailed in Bastad, Sweden where nineteen teams from seven countries battled it out for the title of World Champion. This year organizers are expecting twenty five entries to showcase their skills in the highly competitive and beloved Farr 30 One Design.
Much to the relief of the fleet, former Class President and three time Farr 30 World Champion, Deneen Demourkas will not be sailing this event however, she will be onsite to offer words of wisdom and to present the Royal Canadian Yacht Club Trophy to the newly crowned World Champion. Demourkas, who has competed in every Mumm-Farr 30 World Championship since 2003 said 'it will be very strange to sit on the sidelines for this World Championship and I'm not a very good observer of sailing, I get quite frustrated simply watching'. When asked why she will sit this one out? 'It's time to open the door. I love this Class, I love this boat and I find nothing more satisfying to sail than the Farr 30 however, its time to pass the torch.'
You can bet Class stalwart Harald Bruening of Germany has his eyes on the prize. He too has been sailing the Farr 30 as long as Demourkas and with a string of top five finishes at World Championships, he has yet to win it. 'This is our year' says Bruening. 'Our boat is perfect, our crew are hungry and we are ready to fight.' Class President Patrick Lindblom is very pleased with the winning bid from KDY stating 'Copenhagen is an ideal location from a geographical point of view, a location that allows for good logistics, but more so, offers a fantastic sailing arena on the waters outside Copenhagen. And with a new fantastic club house, we can be sure to enjoy some great social activities off the water. Conditions on the water offer the challenges you would expect from a World Championship, strong currents and rough seas if the weather conditions allows'.
The NOR will be posted after March 1,
Event Website:
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If you want to link to this article then please use this URL: www.sail-world.com/119610
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Our opinion: Governor needs to oppose gross receipts tax
Advice to Fairview residents: Don't sign the recall petitions
Our opinion: Kate Brown snubs voters and tradition with debate decision
High price will doom Gresham-Barlow bond
Our Opinion: Gross receipts tax would only hurt those it aims to help
Troutdale names officer, citizen of year
The Troutdale Police Department named Sgt. Marc Shrake as the officer of the year, honoring his more than 20 years of service, during the department's annual awards ceremony Wednesday, Feb. 22.
Shrake has been involved in the countywide computer conversion, the emergency radio systems upgrade and the new in-car video systems. He also has taken on a major role in the design of the new police department. Shrake has also served on inter-agency teams including the Major Crimes Team and as a hostage negotiator on the SWAT team.
The department also gave a community award to Kathy Scott, a Neighborhood Watch block captain. Scott was credited with bringing her Neighborhood Watch program back to life. With her help, last summer's National Night Out event was attended by more than 100 people.


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Fast and Furious
"Online ordering a snap and delivery above expectations"
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Great bubble wrap
"Shipment arrived on time as promised and was very well packaged. No after order service required."
Quick delivery, very easy website, good price.
"I would order from them agian."
Sony TV Mom's Bday present
"My mom love her new Sony 32 LED from ABT. It came prompt and was a good deal."
They sent me a used vs new part
"The subzero air filter I ordered did not come in a sealed bag as all other filters I've purchased from other venders did. Rather it came inside an old box and had filter residue and scratches all over it. It looked as though it was used for months and then sent to me as a used item. The phone rep I spoke with was very polite and forwarded a return label. She went on to explain they would forward a new one. I returned the "used" filter on June 17th. As of June 28, I still have not received the new replacement. I'm not impressed. "
A rep from Abt Electronics / ABT, abt-cg, has responded
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Known for Customer Service, didn't get customer service
"Ordered a refrigerator on line. Followed up with Abt Customer Service, requested fridge door to be flipped, so it opens from the other side. Received a response advising there was extra charge for this service. I agreed to the extra charge. Fridge delivered and set up, door opens on wrong side. Can't blame the delivery team, they were above average. "
A rep from Abt Electronics / ABT, abt-cg, has responded
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Impressed and Cooler
"Customer Service rates more than 4 stars!! Emails, phone calls, personal service - Wow! I would certainly order from them again and recommend them highly. Air conditioner arrived in one day,"
Very nice and knowledgeable delivery/installation gentlemen
"Kept me updated on delivery time. Arrived when they said they would. Did an awesome job installing and explaining what they we're doing."
Everything was great!
"I had to return the item because I mis-measured. They were so unbelievably helpful."
"Item was delivered promptly, and as described. Excellent pricing. Would recommend that items be placed in overpack box to minimize risk of damage and wear to retail packaging."
JL Audio speakers
"Excellent price & FAST shipping. Speakers were a big improvement to the speakers that came with the boat. Good bass and excellent sound. "
Very strange Company
"Ordered a Maytag microwave and Maytag Oven, they cancelled order several times -- said were afraid of fraud, finally ordered, delivery ser for today, arranged to meet trucker, got call, order cancelled, no explanation. Called ABT, they said vendor cancelled order and they would figure out what is happening. No return calls, nothing.
I paid for these items 3 weeks ago via Master Card and I have paid my MC bill. I have nothing, crazy!!!!"
Great dreyer!
"Arrived just like promised and had no problems with the machine. This is the second time ordering and am very pleased.
"Great company to do business with!!"


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Bernie3K, that does not look too bad at all, definitely worked on worse so what to do. Rake the biggest lumps off I would not bother getting on my knees to do it, rake as flat as you can manage, dragging a flat edge batten over it tells you where the bumps and dips are.
Right our council dump collects waste plant matter to compost then allows so many free bags, worth a try. If not we can get from local GC's three bags of compost for ten pounds or asking on line can often get some one wanting to get rid of soil. Spread the compost mixed with some washed sand on the garden and level using the batten again the idea being to raise the level where you need a lawn. At this stage you could draw up a plan for some hard standing and some grass up to you though a seating area usually needs some hard standing think about it. You can sow lawn from now until October I once put down a small lawn with grass rolls ten days before Christmas and it thrives well now.
The idea would be do not look on it in dismay, look on it as a clean canvass for you to make your own Eden, if you dragged the best soil to the place you most want grass then used pots of all sizes to make a border plus a seating area it will become manageable. We have all struggled at times though us tough old gardeners shrug and get on with it, do not lose heart, I see a very good working area in progress it just needs you to stand back and make a workable plan. Good luck.
Grew up with Paeonia as I have said before on here a very beautiful but frustrating plant, my garden has several Paeonia Lutea Ludowii, Paeonia Rubra Plena. One came from Dads Garden a huge plant that he thought may have been planted by Great grandma Brown in the 1890's. That took seven years to flower but worth the wait.
You can with great care cut off the newest growth on the outside of the root ball and replant they will take up to five years to flower. Never cover the root ball though I mulch around the root in a circle keeping away from the actual root. They like plenty of water, after flowering I leave them alone, growth dies off but provides some cover for the root against frost in winter then clear all the debris from the root and mulch as above. They will give years of joy, I love them.
Simon, having moved quite a few times with various G/ houses the last move cured all previous mistakes in that I bought a Robinson, a good well made aluminium which for thirty years has worked perfectly. Costly yes, buy cheap you get cheep. In high winds some around lost everything, mine never moved and not a single broken glass, fingers crossed.
one row of slabs up the middle, the south side dug out lined with heavy plastic and small shingle, this holds water so tomato's thrive on it I use twelve inch pots with large holes in the base, half fill them and plant the tomato then top up with compost every couple of weeks. North side are the benches, home made from solid wood and a heated sand bed. Through the years heating a g/house got more expensive and each method of heating has its problems. The sand bed gives bottom heat to start seed then shelving above means they can be lifted up as less heat is needed. Hang a bubble wrap blanket around the sand box to contain the heat. The rest of the bench for pots the potting bench is in my garage so do not need roomto work in g/ house.
We all do things differently so pick and choose from any advice given.
Well done each and all, this is my last before bed.
A neighbour purely by chance
Saw me watering the plants
She said in dismay
No no not that way
Now go and zip up your pants.
Goodnight all,
"Oh Dear"
We have a neighbour Plant Pauper
Up to things she shouldn't ought-er
Now she's up on the roof
Which gives us the proof
She's much madder than we thought-er.
Mr Darcy????? Well I did come out of the North Sea after swimming bare chested. All loose bits vanished including fingers and toe's, chest a mass of goose pimples, knees and face purple and two crabs attached to my ears, but we NE lads are tough I would be back to normal in a week?
It would be more Mr Darcy after swimming in the Suez Canal and we did come out of the Sinai hot sweaty and dirty to find the Cantara bridge was closed, I stripped off the lot and dived in the Canal to my horror hearing female cheers as I went under. The canal is quite narrow there so raising my head found a coach load of WAAF on the other bank. What to do? I enjoyed my swim then boldly got out to a lot more cheering, when in deep s--t do what you have to do as normal, it is too late anyway.
Don't worry "J" my spurs have long since gone.
PP, try the bathroom with a funnel and long pipe.
My compost is something to see
Fresh hot and air flowing free
Something I learned
As it often gets turned
It improves if I go there to pee.
Not to worry "J" I was brought up with horses my Son still has them on the farm. Lazy Mares need a little gentling then a kick with the Spurs, the ones with the sharpened rowels attached.
Don't worry we all do it says he who found a bag of Tulips a year later, mind I was in hospital getting lumps cut off, no excuse really, feeling a bit under should get you out there enjoying the fresh air, very fresh here in the NE.
I would tell the young recruits (lack of knowledge I can forgive, idleness never) they got the message.
Plant Pauper, you are being naughty consider your self spanked. You should read the lazy gardener book there are a lot of laughs but some good advice even for us old hands, problem I cannot remember the Author.
Get a long tray about six inches deep fill with good compost with maybe just a dusting of bone meal, put the large bulbs (if there are any) near the bottom and build the rest up almost touching then water in.
They may only grow leaves, good they will take in the sunshine (if we get any) and fatten the bulb for next year, even if they lay forgotten through winter they will come next year.
I have a mass of Daffodils on the front lawn that have grown in number year on year providing me with a lovely show this year for four weeks, they lay hidden under a tree that over grew so had to go and then_______ lovely. NOW GET YOUR Bottom out there and plant.
Mumble good grief were do we get them from, Frank.


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Wolverine UVF Reg # 6777 (P) (Centenario [Venadito] x Soraya [Jacto]) -2002 15.3 Hh Black Lusitano Stallion -Approved breeding stallion in the APSL…SOLD
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Meet Maggie May. She is a level headed, well started 4 year old Gypsy Vanner/Spotted Draft mare currently standing about 14.3 HH. She has been under saddle…SOLD
~*~For sale on consignment!~*~ Dusty is a handsome 14.1hh 11 year old show hunter pony bought over 6 years ago from a trainer in Aiken. He has been…SOLD
Ellas owner of 7 years has gone to college so she is looking for a new person! Ella recently finished 2nd at the stable view hunter trials, Has done well…SOLD
This guy is as sweet as the come. He Loves the trails and will take care of his rider. Joe is happy to ride out alone or in a group. Go anywhere do anything…SOLD
Video coming soon! Ginger's a 20 year old registered Appaloosa mare, trained with Clinton Anderson techniques. She's awesome on ground work and under…SOLD
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I confess I've had a love affaire with vampires for several years now, especially warrior vampires, the kind found in the books of Sherrilyn Kenyon, Lara Adrian and JR Ward. Though I've been published in Regency Romance under the pseudonym Valerie King--and yes one of my Regency Novellas features a vampire--one day I woke up knowing I had to create my own contemporary world of the warrior vampire.
For some mystical, magical reason, early in the process, my vampires appeared with enormous beautiful wings and it has been the most amazing experience to include flight in my novels, in both battle scenes and scenes involving spectacle.
For more information about my unique take on the vampire mythos, check out my website at carisroane.com and my book release video on YouTube by putting in the search phrase, Caris Roane Ascension.
With every hope you'll enjoy reading my books set in the World of Ascension, All my best, Caris Roane


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Clinical Trials
Cystic Fibrosis | Lung Transplantation | Asthma | Lung Cancer | PCD | Critical Care | Airway Biology | COPD/Chronic Bronchitis/Emphysema | Pulmonary Infections | Pulmonary Hypertension | Sarcoidosis | Bronchiectasis
No current studies at this time.
COPD/Chronic Bronchitis/Emphysema
Idiopathic Bronchiectasis and Dural Ectasia: Is there a correlation? IRB Study #11-1997
Sponsor: UNC NCTRACS
PI: Katherine R. Birchard, M.D.
Co-Investigators: Mike Knowles, M.D., Leigh Anne Daniels, M.D
To determine if there is a connection between idiopathic bronchiectasis and connective tissue disorders, this study will look to see if dural ectasia is more common in patients with idiopathic bronchiectasis, as compared to patients of bronchiectasis of known causes and patients without bronchiectasis.
Contact: Katherine R. Birchard, MD
Cystic Fibrosis
Gene Modifiers in Cystic Fibrosis IRB Study #00-1420
Sponsor: NIH
PI: Mike Knowles, MD
This study has been designed to compare the overall genetic make up of CF patients, in regard to gene modifiers, who are considered to have mild disease versus more severe disease. Blood samples from volunteers will be studied, along with pulmonary function tests and other medical information, in hopes that a connection can be made between genetic make-up and disease severity of CF lung disease.
Contact: email@example.com
Genetic Modifiers of Inherited Liver Disease IRB Study #01-1421
Sponsor: CFF
PI: Mike Knowles, MD
This study has been designed to compare the overall genetic make up of CF patients, in regard to gene modifiers, who are considered to have mild disease versus more severe disease. Blood samples from volunteers will be studied, along with pulmonary function tests and other medical information, in hopes that a connection can be made between genetic make-up and development of CF liver disease.
Contact: firstname.lastname@example.com
Lung Transplantation
No current studies at this time.
Ongoing studies are conducted in the UNC Center for Environmental Medicine, Asthma and Lung Biology.
Lung Cancer
No current studies at this time.
Research Genetic Testing for Primary Ciliary Dyskinesia Using a Panel of Genes (5905), IRB Study #14-1225
Sponsor: NIH
PI: Mike Knowles, MD
Primary ciliary dyskinesia (PCD) is a Mendelian recessive, genetically heterogeneous disorder with defective mucociliary clearance (MCC), chronic oto-sino-pulmonary disease with bronchiectasis, and organ laterality defects in ~50% of patients (Kartagener Syndrome). Despite the need for early diagnosis and expert clinical care in PCD, establishing a diagnosis remains a major challenge, based on the traditional approaches of using electron microscopy and/or ciliary waveform analysis to define abnormalities of ciliary ultrastructure and/or function. The goal for this study is to determine whether a multi-gene (n=30) genetic test panel to confirm a diagnosis of PCD will identify as many as 70% of PCD patients. If this genetic test panel is successful, it will revolutionize the diagnostic approach in PCD, and lead to early identification and initiation of clinical monitoring and treatment.
Contact: Beth Godwin
Longitudinal Study of Primary Ciliary Dyskinesia: Participants 5-18 Years of Age (5901), IRB Study # 05-2997
Sponsor: NIH
PI: Margaret Leigh, MD
Mucociliary clearance (MCC) is the primary defense mechanism for the lung. Inhaled particles (including microbial pathogens) are entrapped in mucus on the airway surface then cleared by the coordinated action of cilia. The volume and composition of airway surface liquid (ASL) influence the efficiency of ciliary function and MCC. Genetic diseases of MCC include disorders in ciliary function (primary ciliary dyskinesia, PCD), and ion transport (cystic fibrosis). The purpose of this longitudinal study protocol is to define age-related prevalence of phenotypic characteristics and the progression of key features of lung disease in subjects with Primary Ciliary Dyskinesia (PCD).
Contact: Beth Godwin
Rare Genetic Disorders of the Airways: Cross-sectional Comparison of Clinical Features, and Development of Novel Screening and Genetic Tests (5902), IRB Study # 05-2979
Sponsor: NIH
PI: Mike Knowles, MD
Mucociliary clearance, in which mucus secretions are cleared from the breathing airways, is the primary defense mechanism for the lungs. Inhaled particles, including microbes that can cause infections, are normally entrapped in mucus on the airway surfaces and then cleared out by the coordinated action of tiny hair-like structures called cilia. Individuals with primary ciliary dyskinesia, variant cystic fibrosis, and pseudohypoaldosteronism have defective mucociliary clearance. The purpose of this study is to collect clinical and genetic information about these three airway diseases to improve current diagnostic procedures.
Contact: Beth Godwin
CTRC-2589 Early Onset and Progression of Primary Ciliary Dyskinesia Lung Disease Prior to 10 Years of Age (5903), IRB Study # 08-0764
Sponsor: NIH
PI: Margaret Leigh, MD
Primary ciliary dyskinesia (PCD), also known as Kartagener syndrome, is a genetic disorder of the cilia, which are microscopic hair-like cells. Cilia work to keep the respiratory system clean by moving mucus that contains debris to the large airways, where it can be coughed out. People with PCD have cilia that do not move properly and therefore are not effective in cleaning the respiratory system. This study will determine when PCD starts and how it changes over time, specifically in terms of how well the lungs work, what germs grow in lung secretions, and how the lungs look on computed tomography (CT) scans.
Contact: Beth Godwin
Cross-Sectional Characterization of Idiopathic Bronchiectasis (5904), IRB Study #10-1523
Sponsor: NIH
PI: Mike Knowles, MD
Bronchiectasis is a type of lung condition in which the lungs' airways are abnormally stretched and widened. This stretching and widening makes it difficult for mucus and other substances to move out of the lungs, encouraging the growth of bacteria and leading to breathing problems or infection. Bronchiectasis can be caused by genetic disorders or diseases such as tuberculosis or rheumatoid arthritis. Researchers are interested in developing better ways to diagnose and treat a lung problem called idiopathic or unexplained bronchiectasis. The goal of this study is to better describe the physical characteristics, radiographic patterns, and airway microbiology of unexplained bronchiectasis and to look for possible genetic links or risk factors.
Contact: Beth Godwin
Critical Care
Statins for Acutely Injured Lungs from Sepsis (SAILS)
Sponsor: National Institutes of Health, ARDS Network
Site Investigators: Shannon Carson, MD & Lydia Chang, MD
The SAILS study is a multicenter, double-blind, randomized, placebo-controlled clinical trial of rosuvastatin versus placebo comparator for the treatment of patients with ALI or ARDS from suspected sepsis. The hypothesis of this study is that rosuvastatin therapy will improve mortality in patients with sepsis-induced ALI.
Modifying the Incidence of Neurologic Dysfunction (MIND-USA)
Sponsor: National Institutes of Health
Site Investigators: Shannon Carson, MD & Lydia Chang, MD
The MIND-USA study is a multi-center, double-blind, randomized placebo-controlled trial investigating the effects of haldoperidol and ziprasidone on delirium in at-risk critically ill patients. The hypothesis is that the administration of these commonly used medications will improve short- and long-term clinical outcomes, including days alive without acute brain dysfunction.
Identifying Effective Strategies to Disclose Prognosis: Physician-Family Communication in Patients with Acute Lung Injury (EC-ALI)
Sponsor: National Institutes of Health
Site Investigators: Shannon Carson, MD & Lydia Chang, MD
The EC-ALI Study is a multi-center, prospective cohort study using both quantitative and qualitative methods to identify effective, acceptable strategies to communicate information about patient care and outcomes to surrogate decision makers. The research plans to determine which communication strategies help accurate understanding and which generate misconceptions about clinical care and outcomes for patients who are critically ill.
Mortality Prediction Model for Prolonged Mechanical Ventilation (PRO-VENT)
Sponsor: UNC
Principal Investigator: Shannon Carson, MD
Patients requiring prolonged mechanical ventilation (PMV) often survive the initial severe stages of their illness, but remain dependent on life support systems. Long-term prognosis is often confusing or uncertain for patients, families, and physicians. In order to help clarify prognosis for these complicated patients, a prognostic model that identifies PMV patients who have a high risk of mortality was developed and validated in a multi-center study. Currently, the study continues to identify variables for this model to predict prognosis earlier on in a patient's stay, as well as predict functional outcomes using both qualitative and quantitative methodology.
Informing Decisions in Chronic Critical Illness (The SIT Study)
Sponsor: National Institutes of Health
Principal Investigator: Shannon Carson, MD
This study is a multi-center, blinded, randomized controlled trial of protocol-driven meetings in which a Supportive Information Team, made up of an interdisciplinary group of palliative care clinicians, provide informational support to families of chronically critically ill patients in order to facilitate communication and decision-making with the ICU physician. The purpose is to learn more about how best to provide support and information to families and evaluate the impact on families of patients on prolonged mechanical ventilation.
Decision Aid for Improving Decision-making for Patients with Prolonged Mechanical Ventilation. (DST)
Sponsor: National Institutes of Health
Site Investigator: Shannon Carson, MD
This study is a multi-center, randomized, controlled trial (RCT) with 6-month follow up to determine how useful the decision aid would be in improving the quality of the decision making process for patients who are critically ill, their families, and the ICU physicians and nurses. The study plans to measure the effect of the decision aid on physician-family concordance, quality of communication and medical comprehension. The study also aims to measure the decision aid's effect on post-traumatic stress among family members, and patients' health care utilization over 6 months.
Airway Biology
Ongoing studies are conducted in the UNC Center for Environmental Medicine, Asthma and Lung Biology.
Pulmonary Infections
No current studies at this time.
Pulmonary Hypertension
A Multicenter, Randomized, Double-Blinded, Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Inhaled Treprostinil in Subjects with Pulmonary Hypertension due to Parenchymal Lung Disease
Sponsor: United Therapeutics Corporation
Principal Investigator: H. James Ford III, MD
The primary of objective of the study is To evaluate the safety and efficacy of inhaled treprostinil in subjects with PH associated with ILD including CPFE.
Contact : Samantha Earnhardt, MPH & Dakota Buhrman
BEAT: A Multicenter, Double-Blind, Randomized, Placebo-Controlled, Phase 3 Study to Assess the Efficacy and Safety of Oral BPS 314d-MR Added-On to Treprostinil, Inhaled (Tyvaso®) in Subjects with Pulmonary Arterial Hypertension
Sponsor: Lung Biotechnology
Principal Investigator: H. James Ford III, MD
The primary objective of this study is to compare the effect of BPS-314d-MR (beraprost) versus placebo added to treprostinil, inhaled (Tyvaso®).
Contact: Samantha Earnhardt, MPH
OPUS: US-based, observational, drug registry of Opsumit® (macitentan) new users in clinical practice
Principal Investigator: H. James Ford III, MD
This study is a prospective observational drug registry developed to characterize the safety profile (including primarily potential serious hepatic risks) and to describe clinical characteristics and outcomes of patients newly treated with Opsumit in the post-marketing setting.
Contact: Samantha Earnhardt, MPH
A Randomized, Double-blind, Placebo-Controlled, Phase II Multicenter Trial of a Monoclonal Antibody to CD20 (Rituximab) for the Treatment of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH)
Principal Investigator: H. James Ford III, MD
This study will compare patients treated with rituximab to those on placebo for change in six minute walk distance (6MWD). The secondary objectives of this study are to compare treatment groups for other measures of clinical disease progression and to determine whether the effects on clinical disease progression are paralleled by changes in selected biomarkers. Additionally, the safety and tolerability of rituximab for the treatment of SSc-PAH in patients receiving stable background medical treatment with prostanoid, endothelin receptor antagonist, PDE-5 inhibitor, and/or guanylate cyclase stimulators therapy will be assessed.
Contact: Samantha Earnhardt, MPH
LIBERTY: A Phase 2, Randomized, Double-BLInd, Placebo-Controlled Study of UBEnimex in Patients with Pulmonary ARTerial HYpertension (WHO Group 1)
Sponsor: Eiger Pharmaceuticals, Inc.
Principal Investigator: H. James Ford III, MD
The primary objectives of this study are to evaluate the efficacy, safety, and tolerability of ubenimex in patients with PAH (WHO Group 1).
Contact: Samantha Earnhardt, MPH & Dakota Buhrman
Pulmonary Hypertension Association Registry
Sponsor: Pulmonary Hypertension Association
Principal Investigator
The goals of the PHAR include 1) measuring and improving quality of care (including assessing differences in adherence to evidence-based guidelines and establishing benchmarks for health outcomes), 2) determining the clinical effectiveness, comparative effectiveness, and cost effectiveness of treatment approaches, 3) understanding risk factors for outcomes and regional/center differences, and 4) facilitating funded clinical trials of new therapies and collaboration with the PAH community at large, including providers, patients, and their caregivers.
Contact: Samantha Earnhardt, MPH & Dakota Buhrman
No current studies at this time.


text:
كس ناعم That`s not accurate.One of the biggest things I`ve missed is my signature Black & Pink racecar paint jobs. كس قحبة Vacuum Kiss - While kissing open-mouthed, slightly suck in as if you were sucking the air from your partners mouth. Angel Kiss - A sweet, comforting kiss. Girls: lean closely into your partners face and as he comes in move and kiss him on the cheek then when he says he wants more kiss him with no tounge.
كسكوس صديقتي جنسية in whatever way you want, knowing that if the news have changed or if you saved your Newsfeed settings since the last time the script was called, it will return the number of news items you specified with the format you specified. Lick Kiss - Just before kissing, gently run your tongue along you partners lip whether it be the top or bottom one depending on the position of your lips.The biggest problem is that too many of the pages on Wikipedia that have to do with our industry start off by saying `This article does not cite any references or sources`. كس مصري PS: Youtube isn`t very good for watching anime. كس قحبة Being one of the most contrasting countries in Southeast Asia, how does Malaysia turn several influencies into indigenous habits, how does it link back to its cultural roots? It`s been a while since we`ve seen you on PSP, Naruto -- and it looks like you`ve grown up. كس مصري The sudden cold blast makes for a sensual explosion, and they will not often try it on you next, as well as get very passionate. كس مصري Belly Ring Kiss This is also only used if your partner has a belly ring.


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text: Close Team Melo vs. Team Philly 0 0 0 More 0 0 0 View Gallery Next Previous Next Reuters Team Melo vs. Team Philly The NBA's latest lockout exhibition pitted Philadelphia's finest against an All-Star squad known as Team Melo, supposedly made up of players from Baltimore but featured stars including LeBron James (Ohio) and Chris Paul (North Carolina). But despite its loaded roster, Carmelo Anthony's team fell 131-122 to the hometown heroes in front of the sold-out Palestra. Click through our gallery to check out the best from Sunday's showcase. 1|12 Reuters Team Melo vs. Team Philly With both teams scoring over 120 points, the game didn't feature much defense, but there were plenty of fouls, as displayed here. Hakim Warrick (pictured left) finished with 19 points and 12 rebounds while Chris Paul scored just six points in a rare off outing. 2|12 AP Team Melo vs. Team Philly The Kings' combo guard dazzled his hometown crowd with an array of moves and finished with 18 points and 18 boards. 3|12 AP Team Melo vs. Team Philly LeBron, Carmelo and CP3 weren't the only players on Team Melo. Kings forward Donte Green flushes home a dunk during the game. 4|12 Team Melo vs. Team Philly LeBron James struggled out of the gate but dominated most of the game, exploding for 43 points and 23 rebounds. 5|12 AP Team Melo vs. Team Philly But it wasn't all smiles for LeBron. In addition to losing the game, The King was booed during introductions and throughout the game. Those Philly fans never let up, do they? 6|12 AP Team Melo vs. Team Philly The namesake of Team Melo, Anthony was drawn to the game after his former Syracuse teammate, Hakim Warrick, convinced him via trashtalking. In a losing effort, Melo finished with 31 points and 17 rebounds. 7|12 AP Team Melo vs. Team Philly The Hornets' superstar struggled with Philly's speedy defenders all night and shot just 3 of 12 from the field. 8|12 Reuters Team Melo vs. Team Philly Carmelo Anthony doesn't look happy as he leaves the floor, but LeBron James was the one to leave the arena afterwards without speaking to reporters. 9|12 Reuters Team Melo vs. Team Philly After being booed in pre-game introductions, LeBron James scored just four of his 43 points in the first quarter. 10|12 Reuters Team Melo vs. Team Philly Chris Paul is hounded -- and fouled -- by pesky Team Philly defender Mark Tynsdale. 11|12 Reuters Team Melo vs. Team Philly Kings center and Philadelphia native Jason Thompson dunks after evading LeBron James' attempt at a block. 12|12 Next up More Sports After taking his fair share of abuse from Floyd Mayweather Jr., the welterweight pug found solace with main squeeze Alexia Garland at a post-beatdown bash at the MGM Grand in Las Vegas. 18 Did You See That? September 23, 2011 0 0 0 0 0 0 0 More Recommended Galleries NBA Brandon Ingram 27 NBA Draft Fashion 2016 0 0 0 0 0 0 0 More NBA A difficult choice among other top picks — including Kareem Abdul-Jabbar, Shaquille O'Neal and Tim Duncan (Oscar Robertson was a territorial pick and LeBron James had a lot more time to improve his body of work and win titles) — but Magic not only won five championships but also rescued the NBA through his West-East rivalry with Larry Bird. He recast the league as an entertainment company led by likable stars. Would the NBA ever have become so popular without him? 30 Best NBA First-Round Picks by Draft Slot 0 0 0 0 0 0 0 More NBA 1952: Minneapolis Lakers 4, New York Knicks 3. George Mikan averaged 21.7 points and 17.4 rebounds, and the Lakers beat the Knicks in seven games. The teams alternated wins and losses in each game. — 1953: Minneapolis Lakers 4, New York Knicks 1. Mikan was dominant again, averaging 20.8 points. The Knicks took Game 1 on the road, but the Lakers won the next four — keyed by two two-point triumphs. 14 NBA Finals Rematches 0 0 0 0 0 0 0 More


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Recipe: Fruit Nigiri
By Hili Sharabani, November 28, 2011
Serves 6
● 100g sushi rice
● 100ml coconut milk
● 50ml milk
● 1 vanilla pod - split lengthways and scrape out the seeds with a knife
● 70g sugar
● 1 tbsp honey
● Sliced mango, kiwis and strawberries
● Rinse rice, then place in a saucepan with the coconut milk, vanilla seeds and pod, sugar and honey.
● Bring to the boil, reduce heat and cook for 15 mins.
● Stir continually until the liquid is well absorbed in the rice.
● When cool, form the rice into small clumps and place sliced fruit on top.
Last updated: 11:19am, November 28 2011
Spiced lamb tagine with currants and giant couscous
A North African tagine typically features slow-cooked, tender, braised meat
A simple Israeli salad
This colourful salad gained popularity on the kibbutz
I converted but now I feel totally rejected
Q I converted to Reform Judaism 14 years ago and got married soon after.


text:
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Collector's Guide to Art Deco: Identification & Values by Mary Frank Gaston
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Hetty Dorval by Ethel Wilson
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About meJust a a middle aged lady who happens to love reading.
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Newly renovated 2BR/1 bth house with appliances (refrigerator, stove) a fenced in yard, attached garage and plenty of occupied dwellings in the vicinity.
SECTION 8 WELCOME!!!! Listing ID 2768187.
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Newly updated 3B/1B house in very quiet neighborhood. Section 8 Welcome! Wont be available until June 1st, 2016 Listing ID 2628482.
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Summer is the perfect time to pick up a book for fun at the Hirsh Library! We have some new books that we've just added to our collection from the New York Times' Best Selling List for Science books. Here's a list of a few new titles that we have out on the shelves:
- David and Goliath: Underdogs, Misfits, and the Art of Battling Giants by Malcom Gladwell
- Brainstorm: The Power and Purpose of the Teenage Brain by Daniel J. Siegal
- Madness: A Bipolar Life by Marya Hornbacher
- Troublesome Inheritance: Genes, Race, and Human History by Nicholas Wade
Is there anything else you're dying to read but we don't have? If so, let us know by recommending a purchase.
Tagged with: new books • science books
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ESPN MLS ExtraTime 2002 sets the new standard for soccer games
Join Winnie the Pooh and his friends on five birthday-themed
All the intensity, pageantry and spirit of college football is
The latest update to EA Sports FIFA Soccer series delivers
Got something to prove? Don't just stand there, bust a move!
Play as Harry Potter In Harry Potter and the Sorcerer's Stone.
Take on the role of your favorite character and join the battle
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Thwarting evil with an arsenal of high-flying attacks against a
Pilot plastic helicopters in a world where the Green Armys
NASCAR Thunder 2003 is a feature-filled racer with a ton of game
Who is the number 1 college football team in the nation? That is
Trigger Man puts you in the shoes of the underworld's toughest
Relive the days when the pinball table was king, but play like
Fans will be able to relive some of the film's most thrilling
Many years ago, King Muscle and the legendary Muscle League
Midway Arcade Treasures 2 features twenty all-time arcade
Tear through 30 Monster events, including brutal stadium
Street Hoops™ is an "in your face" street-style basketball game


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Behind the Scenes of the Rip Curl Mentawai Pro - One of the Best QS Events of All Time
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Horizontal like of rainbow-coloured game pieces on a glossy surface, 3-D illustration
Credit: Simone Brandt
Creative #: 130884586
License type: Royalty-freeRoyalty-free pricing is based solely on the size of the product you need, not the specific use. You don't have to pay any additional royalties on a use-by-use basis. Once you license a royalty-free product, you may use it multiple times for multiple projects without paying additional fees. (Pornographic, defamatory, libelous or otherwise unlawful use of any image is, of course, prohibited.)
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