text:
I am a personal finance and investing blogger. A software designer by profession, I have a passion for economics, business, finance and investing. My personal financial goals are to generate enough passive income to fund my retirement, and along the journey - share my experiences and help the readers.
As I'm a long-term investor, I'll highlight some stockpicks which will have a 5-7 year investment horizon. As I strongly believe a portfolio should consist of a mixture of dividend-paying stocks and growth stocks, my articles will reflect my thoughts on this mixture.
Alasdair started his career as a stockbroker in 1970 on the London Stock Exchange. In those days, trainees learned everything: from making the tea, to corporate finance, to evaluating and dealing in equities and bonds. They learned rapidly through experience about things as diverse as mining shares and general economics. It was excellent training, and within nine years Alasdair had risen to become senior partner of his firm.
Subsequently, Alasdair held positions at director level in investment management, and worked as a mutual fund manager. He also worked at a bank in Guernsey as an executive director.
For most of his 40 years in the finance industry, Alasdair has been de-mystifying macro-economic events for his investing clients. The accumulation of this experience has convinced him that unsound monetary policies are the most destructive weapon governments use against the common man. Accordingly, his mission is to educate and inform the public in layman's terms what governments do with money and how to protect themselves from the consequences.
I hold a Graduate Diploma in Applied Finance and Investment (similar to CFA), and a Graduate Diploma in Financial Planning.
I have 30 years of personal investing experience, and 15 years of professional financial advising experience, including broking experience at ETrade Australia, 7 years as a Senior Financial Planner at Commonwealth Bank of Australia and 8 years at High Net Worth Financial Advising. My business is a mix of young clients growing their wealth, pre-retirees, and retirees wanting income, some growth, and safety.As a global investor I use a macro thematic approach searching for good value and/or high growth. I search the globe for great investments with a focus on Asia, Emerging and Frontier Markets as well as "trend investing". I assess a countries demographics and growth potential. Some trends I currently follow include Chinese shares going global, the rising Asian middle class, Electric Vehicles, Renewable Energy, Energy Storage, Smartphones, 3D printing, and personal robots.
I also love to invest in income producing investments that can grow over time and benefit from compounding....Included here are the near monopoly businesses such as the Stock Exchanges, and the high quality income producers.
I use direct shares, ETFs, mutual funds and some direct property investments.
I am a value investor focused on situations where margin of safety is high including sum-of-the-parts, special situations and operating businesses.
I have an undergraduate degree in mathematics, a post graduate degree in accounting and am a CFA charterholder.
With more than $3 trillion in assets under management and offices around the globe, Vanguard is among the world's largest investment management firms. In serving the needs of financial advisors, individual investors, and institutions, we are guided by one constant: to put clients first.
Dr. Torsten Dennin is chief strategist at Tiberius Asset Management AG in Zug, Switzerland. Additionally, he is founder & ceo of Lynkeus Capital LLC. Prior to joining Tiberius Asset Management AG in 2013, Torsten had been Co-Head Natural Resources at Altira AG / VCH Investments (2010-2013), and Senior Portfolio Manager at Deutsche Bank AG (2003-2010) in Frankfurt am Main, Germany.
Torsten holds a master degree and a PhD in economics; studied at University of Cologne, Germany, Pennsylvania State University, and Schumpeter School of Business and Economics.
Get the highest conviction investment ideas from the world's greatest ideas for $12 per month. The Superinvestor Bulletin builds a portfolio exclusively from the highest conviction investments made by the world's greatest investors. Since the world's greatest investors tend to return 15 to 20 percent per year on average, replicating their best ideas should provide superior returns (without their egregious performance fees).One full investment idea per month (15 to 20 page report) plus weekly updates. Visit our website or contact us directly for a free sample report.
I have more than 7 years experience investing in commodities and hard assets such as gold and silver miners, exploration companies, oil and gas producers, MLPs, and various other sectors.
Analyst & Contributor @ The Morgan Report ( Silver-investor.com) ,
Financial Freedom Fighter looking to quit my day job so that I can live a life worth talking about.
WestPeak Research Association is a capital markets group that aims to create quality equity research while enriching the education of its members through active peer mentorship and structured training seminars.
Investor for some thirty years, sometime partly responsible for investing a large (multi-millions) institutional trust fund. I try particularly to have a global outlook and to concentrate on company fundamentals.
Timothy J. McIntosh serves as the Chief Investment Officer and is the founder of SIPCO. He oversees all aspects of major client accounts and serves as the lead portfolio manager for the firm's U.S. Growth Leaders, U.S. Value Leaders, and U.S. Corporate Bond Portfolios. He acts as the firm's chairman of the investment committee. He served as a Professor of Finance at Eckerd College from 1998 to 2008.
Mr. McIntosh's is the author of The Bear Market Survival Guide and the recently published book The Sector Strategist, which was released by Wiley Publishing in March 2012. He has been featured in such notable publications as the Wall Street Journal, New York Times, USA Today, Investment Advisor, Fortune, and The St. Petersburg Times. He has been recognized as a Five Star Wealth Manager in Texas Monthly magazine and .has also been named to Medical Economics' "Best Investment Advisors for Physicians″ list on a continuous basis since 2004.
Bachelor of Science Degree in Economics from Florida State University
Master of Business Administration (M.B.A) from the University of Sarasota
Master of Public Health Degree (M.P.H) from the University of South Florida
I am a 29 year old father of three, active duty US Marine. I began investing with my retirement in mind and mostly focus on reliable dividend paying companies. I enjoy writing for Seeking Alpha to share my ideas and create discussions with fellow investors. I firmly believe that investing should be made more approachable to the masses and strive to keep my articles simple yet informative. Being on a "fixed" but stable income and lone "breadwinner" in the house creates interesting dynamics and greatly impacts my investing approach. I currently hold in no particular order:
I like writing about all sorts of companies in all sorts of sectors. Recently I've been focusing my writing and even investing dollars on micro/small cap defense facing companies. I will always try to keep it simple and understandable, please hit "Follow" if you would like to read my articles in the future.
DISCLAIMER: I am not an investing professional. As a result anything that I write should not be taken as investment advice as it is my personal opinion at the time. In addition, I am not your fiduciary nor do I understand your personal financial situation. Please perform your own due diligence on any potential investment decisions.
I am an individual securities analyst who seeks for value on the Toronto Stock Exchange (TSX), as well as on the NYSE and NASDAQ exchanges. I am a firm follower of Warren Buffett and his philosophy of investing for the long-term in wonderful businesses with a durable competitive advantage. I am always on the lookout for fantastic businesses priced at a discount to their intrinsic value, from gems hidden in the TSX, to the hottest blue chips on the NYSE. Join me and I will help you find alpha. Portfolio: ATD.B, QSR, AAPL, DIS, TD, TU, SJR, SU, CNI, L, MFC, AVO, CTC.A
A young individual investor from Europe with a focus on building a dividend growth-oriented portfolio to achieve financial independence within the next two decades.
I write primarily about US and European dividend stocks, with the latter one being my main focus at the moment.
My entire career has been spent in industry within the finance and accounting realm. My career started in 1985 and has included exposure to implementing SFASs
I am into dividend growth investing. I started with day trading and segued into investing, which as I understand it is not uncommon.
I'm an individual investor looking to grow my wealth over the long term. I've tried many different styles of investing over the last 25 years and have found that buying dividend growth stocks and reinvesting the dividends is one of the easiest ways to grow wealth over the long term. Over the years, I've owned stocks, options, ETFs, treasury notes, and mutual funds. I operate a blog, HarvestingDividends.com, that provides information on the S&P Dividend Aristocrats and other dividend growth stocks.
My name is Mike McNeil and I'm the author of The Dividend Guy Blog along with the owner and portfolio manager over at Dividend Stocks Rock. I earned my bachelor degree in finance-marketing, own a CFP title along with an MBA in financial services. Besides being a passionate investor, I'm also happily married with three beautiful children.
I started my online venture to educate people about investing and to be able to spend more time with my family.
I used to struggle with the same issues millions of small investors deal with on a daily basis. Which stocks to buy? When to sell them? How to find the time to manage my portfolio? How to diversify? I wasn't into dividend investing until I looked in depth at my portfolio returns and realized I was having difficulty keeping up with the market.
The root of the problem was a very poorly built portfolio that lacked structure and the components required to build a sturdy base. I made good money from the stock market but I was taking unnecessary risk to achieve my investing goals.
From that point on, I was determined to create a portfolio strategy that would allow me to benefit from dividend growth stocks as a solid foundation. Since then, I manage my portfolio with a stress free method that enables me to cash out dividend payments even when the market goes sour.
No information available
Dhierin is the developer of the AeroFuel and Cost Model, which is used in some articles as well and is freely available to premium members on AeroAnalysis. With his Aerospace Engineering background he has a more indepth knowledge about Aerospace products, so most of his articles will be about companies in the aerospace industry or airline industry, comparing products and looking at market outlooks.
Dhierin has accumulated over 650,000 views never failing to spark healthy and thoughtful discussions for investors and aerospace professionals.
AeroAnalysis offers wide variety of services, ranging from providing data and cost models to consultancy possibilities. Check out our website for more information.
Thirty-three year old individual investor building my portfolio towards the goal of retiring with a steady stream of income. Looking for opportunities to learn from others and share my investing endeavors with the SA community.
I am a Civil Engineer, who is married with two young kids. In 2013 I took a more active role in managing my IRA for retirement and decided to publicly share my experiences in building the portfolio as an example for the dividend growth investing strategy.
My interest in investing mostly began in 2005 when I started up an investment club with a few friends from college and has accelerated as I've been reading and learning along the way. Since then, investing and the stock market has become a passion and favorite hobby and I've enjoyed writing about stocks and sharing ideas I have here on Seeking Alpha.
My investing goals are to build a nest egg for retirement and fund college education accounts for my kids. I invest mainly in dividend paying stocks that have shown a history of consistent growth in earnings and dividend payouts.
I am focussed on building passive income through dividend investing. My path to progress is smart saving, sound investing and income through dividends.
My blog can be found at financiallyintegrated.com.
I'm old--not that old--- with a diverse background and mentally sharper than a marble, IE, providing the marble is in one piece..
Retired from a Fortune 500 company with over 40 years investing experience, but still manage to learn something new or different most every day.
I'm an investor and a Chartered Business Valuator (CBV). I have been investing since I was a teenager. I love my work. I manage a private investment company and I specialize in business valuation.
I'm a huge skeptic by nature. If you had to put me in an investment category, I would fall under "contrarian/value" investor. It's not an investment style that I picked but one that reflects my personality.
Regarding my articles, I think to present my ideas present in a neutral light, without any hype or promotion, which is a rare thing these days.
Please note that any articles or comments on Seeking Alpha are not linked to my work, and the opinions or content mentioned are mine personally.
My hobby is investing in stocks and options. I read several investment newsletters and manage a few personal portfolios using different strategies. I blog about my dividend growth portfolio, DivGro, which I started in January 2013.
Retired Pharmacist. Call me Rose. Nose= Knows enough to know I need to keep learning and keeping a great dividend paying nest egg growing upwards.
My 83 stock portfolio is listed here by sector, largest holding by value is listed first.
Consumer Defensive: KO, PM, GIS, MO, TGT, KMB, DEO, PG, PEP, MDLZ, CLX, CL, KHC, HSY, UL.
Consumer Cyclical: MCD, SBUX, GPC, NKE, HAS, MAT, VFC, HOG, HD
Healthcare: JNJ, ABBV, CVS, AMGN, CAH, BDX
Healthcare eREITs : OHI, VTR, HCP, HCN, NHI, CCP.
Energy: XOM, CVX, OXY, VLO,
Tech: AAPL, ADP, CSCO
Tech eREIT: DLR
Industrial: BA, UNP, MMM, CMI, CAT, GWW, NSC, LMT.
Industrial eREIT: STAG
Financial: TROW, MA, V, WFC, MET
Other eReits: WPC, O, XLP, UBA, STWD ,WPG
REIT Hotel: CLDT
mREIT: ARI (very very small position) and NRZ (also small)
BDCs: MAIN, PNNT, HTGC, ARCC, NEWT (small)
Telecom: VZ and T
Utility: SO, XEL, WEC, D, MGEE, DNP, CNP, LNT, FE
DNP is a CEF which predominately holds Utilities.
Updated 6/20//2016
.. boring Progressive, another Atheist, fading Proletarian, yes-LGBTQ, and usual DGIer .. **27 June Long Idea: PM** .. Last week I bought CCE and sold none .. This week I bought KO & PEP and sold ABBV.
> Core: GIS .. KHC .. PG .. CLX .. MO .. PM .. KO .. CCE .. MCD .. JNJ .. XOM .. CVX .. T .. VZ .. SO .. XEL .. SCG .. LNT .. D .. NEP .. HCP .. VTR .. O .. PSA .. MSFT .. QCOM .. UNP .. GE .. COST
> Non-Core: AGNC .. MTGE .. LNCO .. TCRD .. PSEC .. MAIN .. BP .. COP .. KMI .. PAA .. BCE .. TU .. RCI .. SJR
> Core / wife's - not in my Core: NEE .. SRE .. AWR .. CL .. PEP .. HSY .. CVS .. CAH .. ABT .. HCN .. NNN .. WPC .. NSC .. CMI ..
.. Holds the following, from my Core: D .. NEP .. SCG .. SO .. SRE .. T .. VZ .. GIS .. KHC .. KO .. CCE .. PG .. JNJ .. PM .. HCP .. VTR .. KMI .. CVX .. XOM .. UNP .. NSC
-- 28Jun2016: Bought KO & PEP. New full positions for wife's IRA.
-- 27Jun2016: Sold ABBV, in wife's IRA(exposure to Humira and lack of moat-type replacements). +5% cap gains(not div's) for 9 months.
-- 24Jun2016: Bought CCE. New full position for wife's IRA.
-- 06Jun2016: Bought D. Added to my current position. (cash came from CCE special dividend due to merger/buyout)
-- 10May2016: Bought PG. Added to my current position.
-- 28Apr2016: Bought ABT & CAH. New full positions for wife's IRA.
-- 1Apr2016: Bought CVS. New full position for wife's IRA.
-- 28Mar2016: Bought KHC. Added to wife's IRA.
-- 18Mar2016: Bought AWR. New full position for wife's IRA.
-- 17Mar2016: Bought KHC. New full position for wife's IRA.
-- 9Mar2016: Bought NEP. New 3/4x position for wife's Roth.
-- 19Feb2016: Bought NEP. New 3/4x position for wife's IRA and my IRA.
-- 11Feb2016: Bought GIS, JNJ, UNP. Added to my current positions.
-- 9Feb2016: Trimmed MO. Trim from 3.5x to a 2x position. +65% cap gains(not divs) for 2.5 years.
-- 4Feb2016: Bought GIS, PM, D. New full positions for wife's IRA.
-- 3Feb2016: Bought more GIS, PM, D. Added to my current positions.
-- 1Feb2016: Sold STR. Due to cash buyout by D. +28.5% cap gains(not div's) for 43 days.
-- 28Jan2016: Trimmed T. Trim from 3x to a 2x position. +16.5% cap gains(not div's) for 4 years.
-- 4Jan2016: Bought JNJ & STR. Added to my positions.
-- 30Dec2015: Bought D. New full position.
-- 17Dec2015: Bought STR & LNT. New 1/2 positions each.
-- 14Dec2015: Sold WPC(possible split-up of company). -2% cap gains(not div's) for 5 months.
-- 10Dec2015: Sold BAX/BXLT(too low of dividend). +19% cap gains(not div's) for 2 years.
-- 10Dec2015: Sold CCP(too low of credit rating: BB+). +6% cap gains(not div's) for 3 months.
-- 03Nov2015: Bought HSY & NNN. New full positions for my wife's IRA.
-- 02Nov2015: Bought more VTR. These are additional shares to an already full position.
-- 02Nov2015: Bought HCN. New full position for my wife's IRA.
-- 27Oct2015: Bought STR. New full position for my wife's IRA.
-- 12Oct2015: Bought CMI. New full position for my wife's IRA.
-- 05Oct 2015: Bought ABBV. New full position for my wife's IRA.
-- 17Sep2015: Bought PG, NSC. New full positions for my wife's IRA.
-- 15Sep2015: Bought SO, T, VZ, CVX, NEE, VTR, WPC, KMI, SCG. New full positions for my wife's IRA.
-- 10Sep2015: Bought XOM, JNJ, UNP, HCP. New full positions for my wife's IRA.
-- 06Aug2015: Bought more MAIN. These are additional shares to a now full position.
-- 22Jul2015: Bought WPC. This is a new position.
-- 10Jul2015: Bought more UNP. These are additional shares to a now full position.
-- 6Jul2015: Bought KHC on first day of merger of Kraft & Heinz.
-- 6Apr2015: Bought more JNJ. These are additional shares to current position.
-- 26Mar2015: Sold LO(did not want RAI). +50.47% capital gains (not dividends) for 2 years.
-- 28Jan2015: Bought more T. These are additional shares to an already full position.
-- 26Jan2015: Sold NHI(no credit rating). +43% cap gains(not div's) for 2+ years.
-- 8Jan2015: Bought UNP as a new near full position. Added to CCE to make it a full position.
-- 2Jan2015: Sold LTC(failed to raise dividend). +16% cap gains(not div's) for 11 months.
** the sun is a star? we are primates? when I die I'm dead? --- what simplicity. what assurance.
I write about dividend growth stocks on my website www.dividendgrowthinvestor.com.
I am mostly a buyer of high quality dividend stocks, with solid competitive advantages. My holding period is forever, as long as the dividend is at least maintained. I tend to concentrate my efforts on stocks which grow earnings and dividends, which provides outstanding total returns over time. I only focus my attention to stocks with sustainable dividend payments. I am also a firm believer in diversification accross sectors and geographic locations.
I have been focusing my attention particularly to companies that regularly increase dividends to their shareholders on my website. On my blog I share my thoughts on investing in dividend paying stocks that have consistently increased their payments over time and tips on growing my dividend income. I hope that my blog will serve as an inspiration for my readers and that it would change their financial lives for the better.
Visit my website, Dividend Growth Investor (http://www.dividendgrowthinvestor.com/)
Bob is retired from a career in law enforcement including more than 20 years as an instructor of Investigative Interviewing. He is a Dividend Growth investor using dividend yield from low beta stocks for income and preservation of capital. Bob has self managed his portfolio since early in 2011. He hopes to encourage discussion among those already in retirement and receiving income from their portfolios.
My curent portfolio is available here: http://seekingalpha.com/article/3969664-difference-quarter-can-make-1st-quarter-portfolio-review?source=all_articles_title
I believe that everyone needs a portfolio business plan. Here's a copy of ours:: http://seekingalpha.com/article/2426965-our-retirement-portfolio-business-plan-legacy-edition-part-two
A list of Dividend Growth Safety Superstars for the past decade is available here: http://seekingalpha.com/article/2255863-a-review-of-the-dividend-safety-superstars http://seekingalpha.com/article/2266863-a-current-review-of-dividend-safety-superstars-part-two


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1080p fps
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How come most cameras with 1080p Full HD recording capability only has a 24fps rating? Even the newly released iPhone 4S claims to have 1080p 30fps recording camera.
Doesn't make sense.
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Adaptation of a web-based, open source electronic medical record system platform to support a large study of tuberculosis epidemiology
Global health
In 2006, we were funded by the US National Institutes of Health to implement a study of tuberculosis epidemiology in Peru. The study required a secure information system to manage data from a target goal of 16,000 subjects who needed to be followed for at least one year. With previous experience in the development and deployment of web-based medical record systems for TB treatment in Peru, we chose to use the OpenMRS open source electronic medical record system platform to develop the study information system. Supported by a core technical and management team and a large and growing worldwide community, OpenMRS is now being used in more than 40 developing countries. We adapted the OpenMRS platform to better support foreign languages. We added a new module to support double data entry, linkage to an existing laboratory information system, automatic upload of GPS data from handheld devices, and better security and auditing of data changes. We added new reports for study managers, and developed data extraction tools for research staff and statisticians. Further adaptation to handle direct entry of laboratory data occurred after the study was launched.
Data collection in the OpenMRS system began in September 2009. By August 2011 a total of 9,256 participants had been enrolled, 102,274 forms and 13,829 laboratory results had been entered, and there were 208 users. The system is now entirely supported by the Peruvian study staff and programmers.
The information system served the study objectives well despite requiring some significant adaptations mid-stream. OpenMRS has more tools and capabilities than it did in 2008, and requires less adaptations for future projects. OpenMRS can be an effective research data system in resource poor environments, especially for organizations using or considering it for clinical care as well as research.
Peru has the highest incidence of tuberculosis (TB) in South America and the eighth highest burden of multidrug-resistant TB (MDR-TB) in the world
Traditionally, clinical research projects have built custom information systems for each study. Depending on the nature of the study, this approach can be expensive and time consuming, as each system needs to be meticulously tested and documented. In 2008, Lang et al. estimated that proprietary commercial systems for research data management can cost hundreds of thousands of dollars for a medium sized study, cost prohibitive in developing countries
Across study types there are common functional requirements for data collection systems; these include patient-based data collection, cohort analysis, scheduling of appointments or tests, patient identification using bar codes, linking to laboratory information systems, and ensuring security and confidentiality. Software tools created for these requirements can potentially be reused in new studies, reducing time, costs, and quality control issues. Recently, a number of clinical data management tools have become available in developed countries to standardize the management of clinical research data collection
When planning began for this study, we had extensive experience in developing information systems to support the clinical care of MDR-TB in Peru, including management of laboratory data
The epidemiological study
The NIH funded the study ("Epidemiology of multidrug-resistant tuberculosis in Peru") in 2006. This prospective study is designed to improve our understanding of the mechanisms of TB transmission as they relate to drug resistance and other microbial and host factors. It is referred to here by the name used by field staff: "Estudio Epi". The primary study outcome measures are to identify (1) the relative risk of TB infection and disease in household members of TB patients who harbored drug-resistant
Requirements for the system
Design of the information system began in January 2008 as the study protocol was being developed. The goals were to collect demographic and clinical data on 4,000 TB patients and their approximately 12,000 household members. We designed the system considering the following requirements:
• The system would be handling tens of thousands of study subjects and a large number of simultaneous users.
• Data would be collected on paper forms in the field, brought back to the study office, and double entered into the information system.
• Study workers would measure GPS coordinates at each subject's home using hand-held devices containing lists of subjects, with automatic data upload.
• Local developers needed to be able to create multiple data entry forms in a standard manner.
• Reporting tools were needed to support the data center and study staff.
• Data would be de-identified and exported three times per week, and transferred to the research team servers in Boston.
• The system should be supported mostly or entirely by the Peruvian team.
Additional workflow and protocol requirements
Estudio Epi is bound by the requirements of the NIH approved protocol, which includes very strict rules determining who can view identified patient data. Field staff members visiting patients need to have access to names and addresses, but other staff carrying out data entry or other data management tasks should not be able to access identifying data. The protocol includes the use of barcodes for identifying each form and sample in order to speed up data entry and reduce errors. The use of barcodes also offers a reliable way to ensure a patient's records are linked without the use of names.
The national TB guidelines in Peru called for the use of tuberculin skin testing in household contacts younger than 15 years old
We used a software system called OpenMRS—the Open Medical Record System. OpenMRS was founded in 2005 as a collaboration to create common software tools to build EMR systems for use in developing countries
The design of OpenMRS offers a number of advantages for the development of research data management tools. Due to the focus on safe collection, storage, and management of clinical data, it includes auditing of data changes in the main database tables. This feature allows tracking of the history of changes in data items linked to the login of the user (although the original version of OpenMRS did not provide auditing of all required items for the study). There is a strong security system to ensure that only the authorized users have access to the clinical data, with the use of encryption of data transmitted over the web using Secure Socket Layer (SSL) Protocol
Using open source software (see glossary) for this project leveraged the design and programming of a much larger community than the specific developers working on Estudio Epi
Customization of OpenMRS for the study
The core OpenMRS software required limited changes; most additions described below were made in a separate OpenMRS software module.
Encoding of foreign languages
To handle the Spanish translation the core OpenMRS software required improvements to the system for supporting foreign language encoding (technically UTF-8 encoding)
Reconciliation of data entry discrepancies
At the time that we began to design this tailored system, OpenMRS routinely used a proprietary form-creation tool called Microsoft Infopath (Infopath, Microsoft, Inc., Redmond, WA). Double entry of data and reconciliation of errors was achieved by capturing Infopath data submissions and storing them in a holding table rather than allowing OpenMRS to process them immediately. This allows a senior data manager to review both entries and make corrections.
Linking to Global Positioning System (GPS) devices
Links to existing laboratory data
Linking data from the public health laboratory was a priority for the study. The initial plan was to use the existing TB laboratory information system "eChasqui" developed by our team
Role-based security tools and applications
As required by the study protocol, we designed the information system such that the data entry staff never saw a participant's name or address. The OpenMRS user privilege/role architecture was used to define which user could see what information; applications accessible were based on a user's login. The data entry staff members never actually saw any of the "default" OpenMRS interface, just the components of the user interface for the Estudio Epi module that were allowable based on their specific privileges.
Auditing of changes in data entered was mainly achieved using the built-in tools in OpenMRS. Some additional tables had to be added to the database (using the study module) to track data items like patient encounters and some demographic data. This ensured that the system was compliant with FDA 21 CFR Part 11
Reporting tools and data export
Reporting is essential to assist study staff in ensuring that all data have been entered for each participant and in tracking potential data quality problems. We created a tailored reports module to allow the Peru-based programming team to program reports. These were mainly developed for the study coordinator and data managers to help administer the data entry process and to manage data updates.
The statistical analysis of the study data set required a full extraction of the data. The main tool for this purpose was written in SQL (a database language) and SAS (SAS Inc., Cary, NC) by the study staff. This tool is run on a de-identified version of the database that is automatically transferred to Boston three times a week. The end result of this process is a SAS-ready data set for analysis. This was the preferred approach by the statistical team; there are now tools in OpenMRS to automate many types of data export for users less experienced in programming.
IT infrastructure requirements were relatively simple, with a server accessed locally in the study office and over the Internet, standard Windows client computers, and bar code printers and readers for sites where patient registration occurred. Twenty Garmin GPS devices were purchased to track the location of each patient's home and place of work. Data backups were performed nightly both on and off site. The information system was programmed by the lead developer (DT) who spent five months based in Lima, and trained three Peruvian programmers to develop and support the system during that period (including one of the authors, JT).
The OpenMRS system went live in September 2009. Figure
Figure 1
The work flow for data collection in the Estudio Epi System (MSLI stand for the Massachusetts State Laboratory Institute)
The work flow for data collection in the Estudio Epi System (MSLI stand for the Massachusetts State Laboratory Institute).
Figure 2
New patient entry per month in the OpenMRS system
New patient entry per month in the OpenMRS system.
In August 2011 there were 208 direct users comprised of data management staff, field staff, laboratory staff, warehouse staff, and research staff. Figure
Figure 3
A field data collector taking GPS reading in northern Lima
A field data collector taking GPS reading in northern Lima.
Performance and support
Evaluation of the system was based on performance and reliability, as well as its ability to meet study requirements within time and cost constraints. The OpenMRS system launched on time and has run without significant breakdowns since then. Subsequent to the initial development period it required a further two months of support from the senior programmer. The Peruvian programmer worked full time during year one and half time in year two. Extra programming support was required to accommodate several changes in the study protocol that affected the processes for collecting and managing laboratory data as described in the methods. The main cost of implementing the software was the salaries for the programmers who added new functionality to the early version of OpenMRS; however, these adaptations have made the system more accessible for subsequent research studies, as well as more cost effective in the long term. A major workflow challenge identified was ensuring that data collection forms filled out by field-based staff were entered into the system in good time, this was a motivation to look at methods for direct field based data collection.
It is uncommon for a research project of this sort to use an Electronic Medical Record system platform to create the study database. This decision was motivated by the large size and complexity of the project, and by a desire to create stable and flexible tools that would be easily supportable. OpenMRS was able to be effectively tailored to the requirements of this study within the time frame required. The intention was also that the system could be reused for other studies within our organization and more broadly as part of our international development projects, a major benefit of open source software. In 2007 OpenMRS had already been tested in several countries with tens of thousands of patients, and was able to handle the large volume of data collected and managed in Estudio Epi without problems. Key benefits of using an existing software framework like OpenMRS include stability and reliability, availability of expertise and training materials, a wide range of existing functionality in software modules, support for a range of open standards for medical data coding and transmission, and a support network of programmers in our organization and the broader OpenMRS community. It can also result in a shorter time to create the system, especially if specialized functions are required as was the case for this study. Table
OpenMRS has also been used for research data collection in other projects in developing countries. Examples include the NIH funded IEDEA studies in East Africa, which collect data on HIV care in Kenya, Uganda and Tanzania and compare clinical outcomes
Problems and challenges
In order to create the database and system for this study, significant additions to OpenMRS were required initially, partly due to the relatively early stage of development of the overall OpenMRS system framework in 2007. The OpenMRS core worked well and has been successfully upgraded from version 1.4 to version 1.6.3. Almost all functionality was put into an OpenMRS module simplifying support and updates to the study specific enhancements. The lead Peruvian programmer (JT) continues to maintain the system and extends it to support new forms and reports. He identified several challenges with the system, including difficulties with special characters in Infopath forms, and the process of designing the forms to link to the concept dictionary. These issues can now be addressed more easily with the open source "HTML form-entry" module and a new reporting framework. Upgrading to new versions of OpenMRS can also require specialized support depending on which software modules are in use. A need for better technical documentation was also noted, and is being addressed with new training material and videos on the OpenMRS web site
The biggest technical challenge in adapting and using OpenMRS relates to the data model based on the concept dictionary. Despite the many benefits of the design for data collection (as described above), such designs can make data extraction and use more complicated than a custom designed relational database. This complexity is partly due to the need to collect longitudinal clinical data with unspecified numbers of forms, laboratory results or other data etc. Creating the "flat" spreadsheet representations expected by statistical programs such as SAS (SAS inc., Carey, NC, USA) requires considerable transformation, particularly when the concept dictionary data model contains hierarchies that group together data items as OpenMRS does (for example to group results of drug sensitivity testing of mycobacterium by antibiotic type). A new OpenMRS module has recently been created to simplify the export of data sets for statistical analysis. This module creates one or more rows in a spreadsheet format for each instance of a particular form entered for a set of patients, and allows customization of which subjects and data items are exported. We had to create clear policies regarding who can see different types of data or groups of patients, and what tools and elements of data extraction tools should be available for whom and for what purposes. These rules, as well as the work flow and software, had to be updated after the commencement of the study but are proving useful in other PIH projects.
A number of problems have to be overcome to achieve effective data collection and management in resource poor environments
• Infrastructure including hardware, power, networking and often internet access.
• Staff to carry out data entry, data management and quality control, IT support and software support.
• Training for the core staff and other users of the system.
• Leadership and management to ensure that the key aspects of the system are prioritized and supported and problems addressed promptly.
• Software.
Considering the interlinked nature of these five requirements, it is essential for all five to be fulfilled in order for the project to succeed. In developing countries it is particularly important to have software that is stable, easily updated, supported locally and well documented. It is also beneficial to have more than one programmer who knows the system and who can develop local programming and IT capacity. Too often projects rely on foreign technical assistance which can cause long delays and is expensive, especially for projects that are not funded with external grants.
Many research data management systems are dependent on reliable internet access. Internet was available in Lima, but is a major challenge in other parts of Peru and in most developing countries. We needed to use local servers for rapid response and to ensure patient-identifiable data remained in the country. In PIH-supported clinical care projects in Rwanda we have developed a system for intermittent synchronization of data between clinical sites and a master server, which could potentially be used for research studies in sites with unreliable internet.
Alternative research data management systems
At the start of Estudio Epi there were few suitable options available for research data management
Another system with increasingly wide use is Project REDCap, a web-based clinical trial management system developed at Vanderbilt University
As the scale of the Estudio Epi study grew it became clear that the workflow and productivity of field staff would benefit greatly from the ability to enter data directly into mobile devices such as cell phones or PDAs, an approach we had previously validated with laboratory data in Lima
Another area of active development for OpenMRS is improved interoperability with other health information systems, including those for managing laboratory, pharmacy, and genomic data. It is now possible to export data from OpenMRS to i2b2, an open source system that allows users to create queries across multiple clinical and research databases such as EMRs and genomic databases
Developing countries are increasingly implementing policies about who can access and use clinical data for research purposes. The tools and experience gained from the adaptation of OpenMRS for Estudio Epi will help improve the management of data in accordance with these rules in other countries, such as in Rwanda where PIH is currently rolling out this system for a large clinical research study.
The choice of systems for research data collection is now growing with good options for stand-alone clinical studies in sites with reliable internet access. Our experience and that of other users suggests that OpenMRS has a valuable role for research data collection in resource poor environments, especially if there is a need to collect data for both clinical and research purposes, or to link to data sources such as laboratories using coding and data exchange standards. Our team and the OpenMRS community are continuing to improve the tools available. With an installed base in more than forty developing countries, there is great potential for OpenMRS to improve support for clinical research either alone or in combination with other systems.
Availability and requirements
All software, source code, documentation and training materials is available for download at
Written consent was obtained from the person pictured for the publication of the photograph in Figure
Information system: used here to refer to the software to manage data. It can also be used to describe the broader aspects of information collection, flow and use.; Database: a piece of software that is used to store and retrieve data. It is part of the software of an information system.; Open source software: software that is freely shared with all users including the underlying source code that is written by the programmers. Users can examine and modify the code but have to share improvements with the broader community. It includes an open source license which specifies the extent of the code that must be shared and is hosted on a web site that allows downloads of the source code plus documentation and often full working versions. If these rules are not strictly observed organizations may not be confident that they will always have access to the source code.; 21 CFR Part 11: US federal government regulations governing the design, programming, testing and use of software for managing clinical research data. They apply to studies that are regulated by the FDA such as certain clinical trials. A particular focus is the auditing of any changes in the data collected such as edits and who made them to ensure data integrity
Competing interests
The authors declare they have no competing interests.
Authors' contributions
HF conceived of the original plan to use OpenMRS, oversaw the initial stages of the work and led the writing of the paper. DT designed the software modifications for OpenMRS and with JT programmed and implemented the system. He also co-wrote the paper. JT programmed substantial parts of the system, and supported the system on a daily basis. NG designed much of the workflow for the cohort study and co-designed the workflow of the information system. LL led the cohort study in Peru and oversaw the development of the protocols implemented by the information system. MM conceived of the cohort study and provided overall leadership. MB conceived of the cohort study and provided overall leadership, and co-wrote the paper. All authors provided critical comments and ideas for the paper and read the final draft. All authors read and approved the final manuscript.
Authors' information
HF is an assistant professor at Harvard Medical School, a research associate at the Brigham and Women's Hospital, and a co-founder of the OpenMRS project.
DT is a Java programmer and public health specialist with a focus on medical information systems.
JT is a Java programmer at Partners In Health in Peru.
NG is a nurse and study manager at Partners In Health in Peru.
LL is a senior TB specialist at Partners In Health and the local PI of the cohort study.
MM is a professor at Harvard Medical School, Co-PI of the cohort study, and PI of the U19 award.
MB is an epidemiologist and associate professor at Harvard Medical School, Co-PI of the cohort study, and PI of the U01 award.
We are grateful to the following individuals for their help with the OpenMRS system and the preparation of this report: Darius Jazayeri, Michael Seaton, Ben Wolfe, Jerome Galea, Sidney Atwood, Zibiao Zhang, Renee Orser and Jonathan Payne.
The study and the development of the information system was funded by NIH grants numbers U01 AI057786 and U19 AI076217. Some components of OpenMRS described here were developed with the support of the Rockefeller Foundation. The funders had no role in the design of the system or the study, in the writing of the manuscript, or in the decision to submit the manuscript for publication.
Global trends in resistance to anti-tuberculosis drugs. World Health Organization– International Union against tuberculosis and lung disease working group on anti-tuberculosis drug resistance surveillance
Extensively Drug-Resistant Tuberculosis: A Comprehensive Treatment Approach
Could an Open-Source Clinical Trial Data-Management System Be What We Have All Been Looking For?
Heterogeneity prevails: the state of clinical trial data management in Europe - results of a survey of ECRIN centres
Research electronic data capture (REDCap) – a metadata-driven methodology and workflow process for providing translational research informatics support
Informatics tools to monitor progress and outcomes of patients with drug resistant tuberculosis in Perú
Electronic lab system reduces errors in National Tuberculosis Program: Cluster randomized controlled trial
Cooking up an open source EMR for developing countries: OpenMRS – A recipe for successful collaboration
Human factors for capacity building: lessons learned from the OpenMRS implementers network
Open MRS Collaborative Investigators. OpenMRS, a global medical records system collaborative: factors influencing successful implementation
A web-based laboratory information system to improve quality of care of tuberculosis patients in Peru: design, implementation and evaluation methodology
Cohort Profile: The international epidemiological databases to evaluate AIDS (IeDEA) in sub-Saharan Africa
Using Electronic Medical Records for HIV Care in Rural Rwanda
Evaluation of computer-generated reminders to improve CD4 laboratory monitoring in sub-Saharan Africa: a prospective comparative study
Combining vital events registration, verbal autopsy and electronic medical records in rural Ghana for improved health services delivery
Implementing medical information systems in developing countries, what works and what doesn't
On selecting a clinical trial management system for large scale, multi-centre, multi-modal clinical research study
PDAs to collect tuberculosis bacteriology data in Peru reduce delays, errors, workload, and are acceptable to users: Cluster randomized controlled trial
Implementing mobile phone-based data collection in a large cohort longitudinal study in Lima, Peru
Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2)
Pre-publication history
The pre-publication history for this paper can be accessed here:


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The MPEG Industry Forum (MPEGIF) will conduct "The New Television Experience" master class Sunday, April 13, at NAB2008.
The full-day class will explore how new technologies are changing the way digital multimedia is created, compressed, delivered and monetized. Business and technology leaders will share their experiences and insights. The class will feature keynote speakers from Yahoo, the Open IPTV Forum, T-Com and MobiTV.
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Redstone Urges Viacom Directors to Quit Fight
Syndication Ratings: 'Live' Leads Talkers for Third Week in a Row
Patterson: No 'Animal of the Week' for New 'Zoo'
Sling TV Refreshes UI on Roku
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Cedato rolls out Open Video API
Trace acquires Buni.tv
Shahrzad Rafati to give IBC2016 Conference keynote
Short Film Creates Human Snapshot of Refugee Crisis
Research and Development: Blackmagic URSA Mini 4.6K Proves Worth the Wait
10 Days, 2 Cameras, Infinite Possibilities: Creative Production Solutions for 'Be Somebody'


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text: Tuesday, June 28, 2016 - What begins as a casual conversation can quickly turn into a heated debate today. Although you know exactly what needs to be said to make your point, you might become so upset that nothing comes out of your mouth at all. Ironically, this argument could be won by what you don't say. The only sensible response may be to declare the conversation over and let it go. Rather than agreeing to disagree, sometimes it's better to just smile and be quiet.Personalize Your Horoscope


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Some say the blade is cursed and brings despair to any who own it, others believe that it is merely coincidental misfortune.
The bard tuned his lyre for the 5th time. He looked at his reflection in the mirror. Ancient eyes greeted him. This would be his last performance, it had to be perfect.
The jaguar stood at the door of the temple. The smell of blood from within assailed his keen senses. He placed one paw, and then another, over the threshold. The priest walked to the door, as the sun's light faded, and greeted the warrior Tepiltzin.
The party had driven the beasts to the edge of the cliffs, the kill was swift. Tlilpotonqui smiled broad and warm. It had been a fine day. His smile faded as he spied the crescent Moon already hanging delicately in the sky. The west was fading to pinks and golds. In his excitement, he had forgotten the time. He fell back, letting the party get well ahead, and turned towards the cliffs. As the last rays of the Sun faded he dove towards the rocky waters below…
On a certain continent, nearly all kingdoms worship under the same pantheon. However, in the southern reaches the peoples take a much more...liberal stance on their Gods. Statues are nude, and very anatomically correct, and icons are often startlingly brazen. For instance, the icon of (insert name), the goddess of love, is an image of two nude twins embracing in a passionate kiss, signifying the love of both family and partner. This is a source of unending outrage and offense for the Northern churches, whose traditional and modest take on religion is constantly at odds with the near-blasphemous ideals of the Southerners. While this is not enough to provoke outright conflict, there is more than enough simmering discontent and long-held grudges between the two hemispheres.


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Getting to the Bottom of Borax: Is it Safe or Not?
Not one single natural ingredient has me quite as verklempt as borax.
Nearly every "green cleaning" site lists it as a wonder cleaner. Natural beauty books are rife with suggesting it as a hair softener. People put it in lotions all across the world.
And upset commentors have left diatribes and sent consternating emails about my recipes using borax proclaiming it "toxic!" "dangerous!" "harmful!" "poison!"
Not surprising, all of the confusion, given the severe lack of cohesive information out there about the safety of borax. The Borax Council has done a terrible job at educating the public. Probably because I just made the Borax Council up.
I think I've gotten to the bottom of most of it, though, and maybe what I've found will help you make a decision as to whether you want to use it in your green cleaning (and beauty) routine … or not.
What IS Borax?
Borax, also known (most predominately in the way we're talking about right now) as sodium tetraborate, is a boron mineral and salt that's mined directly from the ground.
Borax is not boric acid.
That's where the majority of the online confusion appears. With no surprise; at least half of the studies I've found and citations I've read have listed their testing matter as "either sodium borate or boric acid."
The difference between the two is: Boric acid is produced when borax is reacted with another acid (like sulfuric or hydrochloric acid). The result is an acid structure (pH of 5.0), rather than alkaline, as borax is (9.3 pH). (I'm not going to get into the "is boric acid safe or not" question here, because that's a whole 'nother can of worms.)
Borax and boric acid are found together in many places, especially volcanic areas where the borax has naturally reacted with sulfur. You can also find both compounds in seawater.
Is Borax Safe or Not?
Sad hint: You still have to make up your own mind. I cannot say yes. And I cannot say no.
Let me tell you what some other people say, though:
- The EWG's Skin Deep Database lists it as a 5-6 (or moderate hazard), but trying to find the studies they used for their rating proved difficult, and the ones I did find were the nebulous "borax or boric acid" test studies.
- Looking through the ToxNet studies on the NIH website, I see very few that are concerning for any major danger (unless ingested in high quantities). In addition, the Material Safety Data Sheet lists borax as a health hazard of 1, the same as baking soda and salt.
- However, the FDA banned borax as a food additive, and the European Chemicals Agency added it to their "list of substances of very high concern" a few years ago. From what I could find, that had much to do with the ongoing debate as to whether excess boron in the soil harms crops.
- Borax is classified as non-carcinogenic and a mild skin irritant. The high alkalinity of borax is likely what causes skin irritation (just as excessive use of baking soda would cause irritation). There are also several studies in the ToxNet database that show its only a very mild lung irritant and causes no lasting damage. In addition, it does not penetrate the skin well, and is not considered to be bio-accumulative. (Meaning, repetitive use over time does not mean it builds up in your system.)
- The one concern is with its potential to disrupt the reproductive system. Studies have not been done in humans regarding this; however, potential reproductive issues in mice are suspected from high levels of (ingested) borax.
- Borax is acutely toxic in the same manner that salt is (in rats, it's 4500-5000 mg/kg of body weight, which is A LOT). Ingested in moderate quantities, it causes gastrointestinal upset and nausea. Bottom line: While it may be listed as "poison" on the box, it's only toxic at very, very high levels. (Like salt, baking soda, and even water is.)
You confused yet?
Here's one more bit of info for you:
Boron is an essential mineral that the body needs for bone building, immune function, and brain function. Plants need it to grow. But, like anything, it's needed in small moderation. Much like salt.
Boron is found aplenty in borax. People even take borax as a supplement and swear by it (I am NOT recommending you do this). That's a little extreme, but I use it as a gauge as to how harmful borax really is.
Borax: My Personal Thoughts
Borax is wholly natural. It doesn't cause cancer, accumulate in the body, or absorb through the skin. It is not harmful to the environment. In fact, the largest borax (borate) mine in the world – found in Boron, California – is considered by many to be the most ecologically sound and environmentally sustainable mine in the United States. This is also the mine where 20 Mule Team comes from.
I'm putting to rest my late-night concerns about whether – all along – I've been using some kind of dangerous(!), toxic(!) poison(!).
For me – and this is my personal determination after months of searching, wondering, and compiling information – borax is just fine to use in my household cleaning routine. ESPECIALLY as a laundry detergent. It's also fine to use, occasionally, as a hair treatment … or even in a lotion.
I'll just be keeping it out of the reach of kids and my two cats. Not that any of those beings would want to eat it anyway. Ick.
My only teeny, tiny, miniscule concern still lies in using it in my dishwasher detergent. But, frankly, the only time I ever see any trace of residue on my dishes when I've used homemade dishwasher detergent is while washing the few plastics that still remain in my house.
I know better than to even be using plastics.
So, going forward, I'll still be using my borax and washing soda dishwasher detergent, I'll just be washing my plastics by hand (and little-by-little getting rid of them all together … except my food processor … anything but that).
And, moreover, I now have a compilation of all kinds of fancy information for the people who come down the road, aghast that I recommend using borax.
Ultimately, I don't think it's that big of a deal.
Do you?
Related Posts:
687 Responses to "Getting to the Bottom of Borax: Is it Safe or Not?"
Read below or add a comment...
The Chicken Littles should ring alarms about human saliva, which naturally contains substantial nitrates. How do we ever survive?
This is a really good article. I appreciate the research. Thanks for helping
He didn't do any research. It is all conjecture. Don't use it in the house.
why do you think it shouldn't be used in the house?
I know of a lot of things that an MD will tell you to clean your house with that is not safe. So WHY should we not use a natural product in our house? Because its not from the BIG PHARM?
I have used this stuff for many years and I plan to use it many more.
Such clear and understandable information. Thank you. I love your writing style – light and humorous, not overdone, but strong content!
Thank you for providing useful information! My hubby has cancer and I've been looking for ways to de-toxify our home. Finding any kind of DIY recipes for cleaning supplies that don't include Borax are few and far between…and the few I did find didn't work well. (It makes me wonder if some bloggers have even tried it themselves, sheesh.)
After much searching and head scratching, I came across your blog and my confusion is now informed clarity :D Thanks for keeping it real.
Thank you for the high-quality info in this post! I'm using Borax to kill fleas in my home. I was wondering if I could leave the dog loose in the house while I let the borax sit in the carpet while I was gone. I'm going to rest easy now, knowing that Borax is just a salt, and my dog will be fine because there aren't any piles or clumps of it sitting around that she could eat.
Does this work for my husband's clothes… He works landscaping and I'm having a hard time finding something that works to get the smell out…HRLP!
I have been trying to find a natural emulsifier, and I have finally found one, ysing beeswax and borax. I was concerned about borax, but thanks for putting my concerns to bed
While scrubbing the floor with a mix of borax and an all organic liquid soap one of the parakeets I share the apartment with flew down and landed in the minimal suds. I shooed him away IMMEDIATELY. The next morning, I found him vomitting. Parakeets vomit into each other's mouths as a sign of affection, but this was just him vomitting up seeds repeatedly but still moving about and eating, making his usual sounds. I went to work concerned but figuring he'd make it through. He didn't, while he was alive and yet still vomitting when I returned after my 8 hour shift, he died that late night, approximately 30 hours after landing in a what was a pretty diluted amount of borax. It had to be the Borax. My thought is he got it on his feet then ingested it. While not highly poisonous to rats, it killed my little bird friend. Ultimately it's my fault for thinking it wouldn't be toxic, and allowing the two boy birds to fly about freely while I cleaned with it.
[…] borax is highly poisonous to ants, but is relatively safe for humans, especially compared to most over-the-counter […]
[…] borax is highly poisonous to ants, but is relatively safe for humans, especially compared to most over-the-counter […]
[…] borax is highly poisonous to ants, but is relatively safe for humans, especially compared to most over-the-counter […]
[…] borax is highly poisonous to ants, but is relatively safe for humans, especially compared to most over-the-counter […]


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text:
Police confirm explosive device removed from SkyTrain tracks
CTVNews.ca Staff
Published Friday, November 2, 2012 6:24PM EDT
Last Updated Friday, November 2, 2012 10:48PM EDT
Police confirm the object removed from Vancouver's SkyTrain tracks on Friday evening was an explosive device strapped to three empty tanks.
After a passenger spotted the suspicious item on the train tracks in Surrey Friday afternoon, police shut down a portion of the line as explosives experts removed the device.
"It's very concerning," Transit Police spokesperson Anne Drennan told CTV News. "We have reason to believe this might actually be a very real pipe bomb."
She said the device was strapped to three propane tanks or small fire extinguishers.
Drennan said authorities will now determine what the capacity of the explosive device could have been if it had exploded.
The canisters will also be tested for fingerprints and other forensic evidence after the explosive device is detached and detonated.
The SkyTrain tracks between Scott Road and Gateway stations were shut down for approximately three hours as police investigated. By 5 p.m. local time, authorities had removed the device and re-opened the line.
"It's just been laid precariously, perhaps even tossed onto the SkyTrain tracks," said Surrey RCMP Cpl. Drew Grainger earlier Friday.
One SkyTrain passenger whose commute was snarled by the closure said he didn't understand how the device made its way onto the tracks, which sit high above ground level.
"Somebody must have brought that up. Someone should have seen them," he said.
More News from Canada
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- Civil libertarian cries foul after Nova Scotia man charged for public profanity


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Dr Michelle A.
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Feb. 21, 1976
Cattaraugus County
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Feb. 12, 2005
Erie County
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Michele A. Bartholomew, PT, DPT
Olean -- Michele A. Bartholomew, PT, DPT of King Street died at the Bertrand Chaffee Hospital, Saturday February 12, 2005 as a result of an automobile accident.
Born in Olean, NY on February 21, 1976 she was a daughter of William E. and Catherine E. Kosinski Foss. On July 31, 1999 at Christ United Methodist Church she married Joseph M. Bartholomew who survives.
Michele graduated from Olean High School in 1994. She attended the University of Buffalo where she received a bachelor degree in exercise science in 1998 and a bachelor degree in physical therapy in 2000. Michele recently completed her Doctorate of Physical Therapy at Damon College. She was employed as Director of Rehabilitation Today in Olean and was a member of the American Physical Therapists Association.
Michele gave of herself to others in many ways. She was active with the March of Dimes where she volunteered and helped children in need. Her final unselfish gift was to donate her organs, so others may live.
Michele loved life and enjoyed having fun. She was dedicated to her husband who she loved so dearly. She was an advocate of physical fitness and enjoyed playing softball, running and exercising.
Michele's interests and talents were broad and diverse and included fashion, plants, cooking, traveling and her dogs, Jazmine, Zulu and Zoey.
In addition to her husband Joe, she is survived by her parents Catherine Foss of Olean and William Foss of Olean; a sister Jennifer L. Foss of Olean; Uncles and Aunts, Paul (Margie) Kosinski of Olean and Karen Venetian of Cincinnati, OH; cousins Andrea Kosinski of Florida, Melissa Kosinski of Olean, Ryan Venetian of Cincinnati and Cara Venetian of Houston, TX.
She was predeceased by her grandparents.
Friends will be received on Tuesday February 15, 2005 from 2-4 and 7-9 at the Casey, Halwig & Hartle Funeral Home, 3128 West State Rd., Olean. A funeral service will be conducted on Wednesday February 16, 2005 at 10:00 AM at St. Bonaventure Church, Allegany. Rev. Gregory Brennan, OFM and Rev. Larry Ford, OFM will officiate. Burial will be in St. Bonaventure Cemetery, Allegany, NY.
Memorials may be made to March of Dimes, 385 North French Rd., Buffalo, NY 14228 or to the S.P.C.A in Cattaraugus County, 2944 Olean-Hinsdale Rd., Olean, NY 14760.
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Numerical Simulation of Cardiovascular Dynamics With Left Heart Failure and In-series Pulsatile Ventricular Assist Device
Version of Record online: 7 DEC 2006
DOI: 10.1111/j.1525-1594.2006.00326.x
Artificial Organs
Volume 30, Issue 12, pages 929–948, December 2006
Additional Information
How to Cite
Shi, Y. and Korakianitis, T. (2006), Numerical Simulation of Cardiovascular Dynamics With Left Heart Failure and In-series Pulsatile Ventricular Assist Device. Artificial Organs, 30: 929–948. doi: 10.1111/j.1525-1594.2006.00326.x
Publication History
- Issue online: 7 DEC 2006
- Version of Record online: 7 DEC 2006
- Received March 2006; revised April 2006.
- Abstract
- Article
- References
- Cited By
- Numerical simulation;
- Cardiovascular dynamics;
- Heart failure;
- Ventricular dysfunction;
- Pulsatile;
- Ventricular assist device;
- Heart valve dynamics
Abstract: This article presents a numerical model for investigations of the human cardiovascular circulation system response, where the function of the impaired left ventricle is augmented by the pumping action of a pulsatile ventricular assist device (VAD) connected in series to the native heart. The numerical model includes a module for detailed heart valve dynamics, which helps to improve the accuracy of simulation in studying the pulsatile type VAD designs. Simulation results show that, for the case with left ventricular (LV) failure, the VAD support successfully compensates the impaired cardiovascular response, and greatly reduces the after-load of the diseased ventricle, thus assisting possible recovery of the ventricle from the diseased condition. The effects of these conditions on pulmonary circulation are also shown. To investigate the effect of different pumping-activation functions (VAD motion profiles) on the cardiovascular response, three different VAD motion profiles are investigated. The numerical results suggest that Hermitian type motion profiles (smooth curves skewed toward early systole) have the advantage of requiring minimum power to the VAD, and producing the minimum after-load to the left ventricle, minimum ventricular wall stress, and minimum ventricular work to the diseased ventricle; while sawtooth type motions need slightly more power input, and induce slightly increased aortic pressure in diastole, thus improving coronary perfusion.


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American Masters TV Show Watchlist
Season 26, Episode 3 Harper Lee: American Masters
First Aired: April 2, 2012
A profile of "To Kill a Mockingbird" author Harper Lee, whose childhood in Monroeville, Ala., provided the inspiration for the classic 1960 novel. The documentary also delves into the making of the Oscar-winning 1962 film; Lee's friendship with childhood neighbor Truman Capote; and the impact the novel had and still has on readers. Included: remarks by Lee's sister Alice Finch Lee.
Cast & Details See all »
- Rating: TV-PG
- Premise: An acclaimed series of biographies of artists, writers, filmmakers, musicians and Hollywood stars. Profiles of Alexander Calder, Paul Simon, Charlie Chaplin and music producer John Hammond won Peabody Awards, while films about Edward R. Murrow, Lucille Bal… (more)
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Salted Nut Squares
Total Time
Prep 20 mins
Cook 0 mins
Haven't tried it yet. Looks good though.
Ingredients Nutrition
- 3 cups salted peanuts, divided
- 3 tablespoons butter or 3 tablespoons margarine
- 2 cups peanut butter chips (12 oz.)
- 1 (14 ounce) can sweetened condensed milk
- 2 cups mini marshmallows
- Place half the peanuts in an ungreased 11x7x2 pan; set aside.
- In a saucepan, melt the butter and peanut butter chips over low heat.
- Add milk and marshmallows, cook and stir until melted.
- Pour over the peanuts.
- Sprinkle the remaining peanuts on top.
- Cover and refrigerate.
- Cut into bars.
Most Helpful
This was very good and very rich. I made mine in a 13x9 pan.
Payday is my favorite candy bar so I was anxious to try this recipe. The stirred mixture is quite thick, so when I poured it over the bottom layer of nuts, it all just glumped together. I spread it out as much as I could, but it was not a pretty sight. That aside, we thought the peanut butter chips were overpowering. Maybe adding more marshmallows would help to tone that down, but I will not likely try again.
This is very good and fast to make. I made this a couple of times with in a three day period for holiday quests. I found that you need to drizzle the mixture over the nuts making sure to cover entire layer, this is easy enough to do if the mixture is warm. I prefer to lightly coat the pan first with oil, (just a fear factor for me :-) Also prefer to use almost 2 jars of nuts because I like all of the nugget on the top and bottom completely covered with peanuts just like the salted nut role candy bars. I too used a 13X9 pan. Will be making more soon I am sure!


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StartUpHire is the place to find Development-Manager jobs in and near . Review the list below of Development-Manager jobs. These Development-Manager jobs represent some of the most rewarding careers available. You can refine your job search for Development-Manager jobs in by adding a job title, company name, or keyword to the search box above … or click the "Advanced Search" link for more options. Don't see the employment opportunity you're looking for? Check back soon for more Development-Manager jobs in , or sign up for an email alert (link in upper left) to receive periodic updates on new Development-Manager jobs in , .
Location:Cambridge, MA Job Code:1402 # of openings:1 Description Job Qualifications: Aurora is seeking an experienced HR professional to support its Research & Development Center in Cambridge, MA. This person will support all HR activities at the site including recruiting,5/15/2016 Cambridge, MA Save This Job
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Location:Redwood City, CA Department:Product Management Description We are looking for a world-class visual and interaction designer for our enterprise SaaS platform! As a member of our product team, you will be responsible for designing the smoothest possible user experience4/24/2016 Redwood City, CA Save This Job
Marketing Mountain View, CA Coursera is transforming the lives of people around the world by providing universal access to the world?s best teachers and universities. In four years we?ve brought over 1,400 courses to over 17 million learners worldwide, and we?re just getting4/24/2016 Mountain View, CA Save This Job
Job Code HR200-153 Job Locations US-PA-Bethlehem Posted Date 3/4/2016 Category IT Type Regular Full-Time More information about this job: Overview: GENERAL DESCRIPTION: The Enterprise Operations Center (EOC) Operations Support Technician is a critical role for Synchronoss in3/27/2016 Bethlehem, PA Save This Job
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text:
Chip w/ Dale's Donkeyhouse, a favorite attraction of Lightning McQueen
Nobody is sure what the appeal of Chip w/ Dale's Donkeyhouse is. It once had a ball pit full of snakes, but overprotective parents had it confiscated to make it harder for kids to get exercise.
Ruin everything with Pirate Mode
© copyright 2011–2016
A Pants Aflame production


text:
sales analyst jobs near East Hanover, NJ
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Digital Business Partner Senior Analyst (Position can sit in Mount Olive, NJ or Brentwood, TN)
Mars, Incorporated - Budd Lake, NJ
Understanding of demand side of the business (Marketing, Sales, Merchandising). A strong working knowledge of relevant digital technologies along sales funnel...
Client Services Manager
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Teamwork is key in Client Services and you'll need to work cross-functionally with other Index teams (Platform Services, Publisher Development, Product, and...
Inside Sales Representative
Basware Inc. - Parsippany, NJ
Sales Skills and interest in developing further in sales. Together with the SMB field sales, other direct sales and partner channel ensure better reach of...
Mortgage Loan Processor- Remote
Mortgage Master - Morristown, NJ
Determine deadlines required to ensure loan closes within the Purchase and Sale Agreement, rate lock and Investor delivery requirements....
Business Development Specialist - New York or New Jersey
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Sales and/or marketing experience in an emerging growth technology sector company is a strong plus. This position will enhance and support the business...
Government Rebate Analyst
Alvogen - Pine Brook, NJ
The Government Rebate Analyst reports to the Director, Sales Operations. The Government Rebate Analyst handles all claims in conjunction with both federal and...
Director, Offer Management
Digital Realty - New York, NY
Indirect Sales Enablement:. Supervise pricing analyst team. Working closely with sales, sales management, product, and solution architects, this position will...
Global Trade and Compliance Manager
Troy Corporation - Florham Park, NJ
Director of Treasury and FP&A, Senior Financial Analyst. Finance, Logistics, Legal, Operations, Procurement, Sales, Marketing, Regulatory and Information...
Financial Analyst - Product Marketing Finance
American Standard - Piscataway, NJ
Reporting to the Senior Finance Manager, the Financial Analysts supports the Product Innovation, Sales, Brand Marketing and Engineering teams in delivering the...
Disclosure Analyst
Home Point Financial - Parsippany, NJ
A Mortgage Disclosure Analyst is responsible for verifying all disclosures and fees and ensuring that all prospective loans conform to federal and state loan...


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A Latin set opens today's show popping right on over to Africa for an Afro Beat set followed by classic oldies and Femi Kuti who played the MN Zoo that evening. We closed witha taste of Zap Mama's latest release… and then the 35W bridge fell a few hours later.
SPECIAL GUEST TODAY: Sandra Samuels – FLOW
and…Melinda J – The Capitol City Diva Herself! co-hosting in
delivering a lot of GREAT ole' school tunes
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Pop Culture
Odd Mom Out Returns & Ginnifer Goodwin's Baby NewsBy Gerri Miller
Find out who's guest starring on Odd Mom Out this season and get the scoop on Goodwin's new babe!Go To Pop Culture
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Introduction to Judaism
Half Jewish? Jewish Identity for the 21st Century Part 2
Queering the Mikveh: Waters of Radical Inclusion
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Manufacturing Development & Deployment Engineer
- Preston, England, Lancashire
- Negotiable
Manufacturing Development & Deployment Engineer Would you like to help operate within a multi-disciplined environment working closely with TX, FCAS, JSF, Typhoon, Hawk and other projects to develop, deploy and support new leading edge manufacturing pr
Information Assurance Practitioner
- England, Cumbria, Barrow-In-Furness
- Negotiable
Information Assurance PractitionerWould you like to join a world class defence organisation and develop your skills in Information Assurance? We currently have a vacancy for an Information Assurance Practitioner at our site in Barrow-in-Furness, Cumbria.A
Consultant Engineer - Information Assurance
- Barrow-In-Furness, England, Cumbria
- Negotiable
Consultant Engineer - Information AssuranceWould you like to have a strategic influence on the development of Information Assurance (IA) policies for a national nuclear deterrence programme? We currently have a vacancy for a Consultant Engineer - Informat
Systems Engineer
- Fareham, England, Hampshire
- Negotiable
NATS is a leading air navigation services specialist, handling 2.2 million flights in 2013/14, covering the UK and eastern North Atlantic. NATS provides air traffic control from centres at Swanwick, Hampshire and Prestwick, Ayrshire. NATS also provides ai
- Recruiter: National Air Traffic Services
Software Engineer
- England, Somerset
- Negotiable
Software Engineer Would you like a role which enables you to make a difference to people on the frontline? We currently have a vacancy for a Software Engineer at our site in Yeovil. As a Software Engineer, you will be developing product solutions in Java/
Software Engineer
- England, Hampshire, Portsmouth
- Competitive package
As a Software Engineer, you will be investigating how technology and data can be used to optimise the services we provide to our clients, including the Royal Navy, and will include unique pieces of equipment at the forefront of innovation.
IM&T Manager - (Product Management)
- England, Barrow-In-Furness, Cumbria
- Negotiable
IM&T Manager - (Product Management) We currently have a vacancy for an IM&T Manager - (Product Management) at our site in Barrow. As an IM&T Manager - Product Management you will be working within the planning support group, responsible for a
Electronics Engineer
Premium job
- Tring, Hertfordshire
Nikon Metrology is looking for an Electronics Engineer to join our Electronics Team based in Tring (UK).
- Recruiter: Nikon Metrology Europe
Electrical Training Officer / NVQ 3 Assessor
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- Norwich, Norfolk
- Competitive + Pension + Personal BUPA cover
As a Qualified Electrician, you know what it takes to complete electrical work to exceptional standards of safety and quality.
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Electrical Training Officer / NVQ 3 Assessor
Premium job
- Dorchester, Poole or Bournemouth
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Diesel cars to pay for low emission zone
Polluting diesel cars would have to pay a fee to enter central London
Drivers of diesel cars could be forced to pay a daily fee for entering the ultra-low emission zone, which is to be established in central London by 2020.
The charge for entering the zone, designed to help the UK capital comply with emission reduction targets, is estimated to cost about the same as the current £11.50 congestion charge.
"When it comes to tackling London's air pollution, and protecting the health and well-being of all Londoners, diesel cars are an issue which must be addressed," said Matthew Pencharz, an environment and energy adviser to the Mayor of London Boris Johnson.
"Over recent years the European diesel engine standards have not delivered the emission savings expected, yet governments have been incentivising us to buy them. This has left us with a generation of dirty diesels," Pencharz said, stating it is necessary for the government to stop incentives that keep driving people to opt for diesel cars.
The ultra-low emission zone, proposed last year by the Mayor of London Boris Johnson is still subject to full consultation but it is expected that all diesel cars not meeting the new standards would be subject to the charge.
However, motoring organisations were less than happy with the proposed scheme.
"This isn't quite a miss-selling scandal, but for years ministers took their eye off the ball and encouraged drivers to buy diesels to help fight climate change," said RAC Foundation director Professor Stephen Glaister. "That has come at a cost: local air pollution. Today 10 million cars in Britain are powered by diesel engines - a third of the total."
According to Glaister the major problem is that although in laboratory conditions diesel cars can meet strict criteria, in real life their performance, when it comes to pollution, is far less satisfying.
AA president Edmund King said that by no means are personal cars, even the diesel-powered ones, the major culprit of air pollution in London. Compared with buses, taxis and trucks, personal cars are rather harmless, King believes.
"The first move should be to target the gross polluters and get them off our roads in order to have a greater and more immediate impact on air quality," King said.
"Drivers are confused as to what vehicles to buy due to mixed fiscal messages from governments over the last decade or so. The goal posts seem to have moved from CO2 (carbon dioxide) to NOx (nitrogen oxides) without fully informing the players."
The Mayor of London Boris Johnson has pledged to fight air pollution in London for the sake of the city's inhabitants. Among the concepts put forward to tackle the issue are fleets of zero-emission capable taxis and low-emission, even electric, buses. By 2020, about 300 fully electric buses should be serving in the streets of London.
Boris Johnson said today: "Improving London's air quality is an urgent challenge. It affects the health and well-being of all Londoners, and it simply cannot be put on hold.
"Here at City Hall we are doing everything in our power to address it. At the heart of this are my plans for the world's first ULEZ in central London from 2020. This will be a game-changer, but with just a little more energy, ambition and action from Westminster and from Brussels, London can meet the EU limits for NO2 by 2020. It is possible, and together we can make it happen."
Hybrid taxis using solar power to charge their batteries are among possible options to tackle pollution in London, watch our video:
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"Where would Frankenstein and his creative mind fit into today's workplace? Should we fear technological developments or embrace them?"


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Want to see what CES will be like in 2027? New Robocop teaser gives us a glimpse
Sony Pictures is ramping up the marketing machine for the remake of Robocop in a style reminiscent of that adopted by Fox for Prometheus. A dedicated OmniCorp website is full of excellent clips and details about the products made by the future weapons manufacturer, all presented as if it were a real company.
But the best offering on the site is OmniCorp's CES 2027 keynote speech, presenting the RC-2000 model (yes, that's Robocop to you and us).
A video has been made in the style of a real CES keynote, albeit using fancy graphics and movie scenes, which reminds us a lot of the Ted presentation made for Prometheus. It's rather cool. Oh yes.
The site will also feature a series of in-browser games that can be controlled by mouse or tablet device. There is also a free game now available for iOS and Android devices. You can find more details at omnicorp.com (and check out the awesome return of the ED-209).
Robocop will be released on 7 February in the UK, 12 February in the US.
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