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Eric T. Shinohara and Adriana Gonzalez contributed equally to this publication.
Original Article
Nuclear survivin predicts recurrence and poor survival in patients with resected nonsmall cell lung carcinoma
Version of Record online: 1 MAR 2005
DOI: 10.1002/cncr.20951
Copyright © 2005 American Cancer Society
Volume 103, Issue 8, pages 1685–1692, 15 April 2005
Additional Information
How to Cite
Shinohara, E. T., Gonzalez, A., Massion, P. P., Chen, H., Li, M., Freyer, A. S., Olson, S. J., Andersen, J. J., Shyr, Y., Carbone, D. P., Johnson, D. H., Hallahan, D. E. and Lu, B. (2005), Nuclear survivin predicts recurrence and poor survival in patients with resected nonsmall cell lung carcinoma. Cancer, 103: 1685–1692. doi: 10.1002/cncr.20951
Publication History
- Issue online: 4 APR 2005
- Version of Record online: 1 MAR 2005
- Manuscript Revised: 15 DEC 2004
- Manuscript Accepted: 15 DEC 2004
- Manuscript Received: 14 OCT 2004
Funded by
- Vanderbilt Discovery Grant
- Vanderbilt Physician Scientist Grant. Grant Numbers: VICC CCSG5, R01-CA88076, R01-CA89674, NCI P50-CA90949
- Abstract
- Article
- References
- Cited By
- survivin;
- lung carcinoma;
- nucleus;
- tissue array;
- mitosis;
- apoptosis
Survivin, which is a member of the inhibitor of apoptosis protein gene family, regulates both programmed cell death and mitosis. It has been shown that survivin expression and its subcellular localization both have prognostic value for patients with malignant disease. In this study, the authors investigated whether nuclear or cytoplasmic staining of survivin was a prognostic marker for patients with lung carcinoma.
Paraffin-embedded tissue blocks from 144 patients with Stage I and II resected nonsmall cell lung carcinoma (NSCLC) were obtained for immunohistochemical staining. Three specimens from each patient were prepared and stained with a survivin-specific antibody. Nuclear and cytoplasmic staining was graded from 1 to 3 based on intensity.
Patients who had nuclear staining for survivin had a significantly increased risk of disease recurrence (hazard ratio, 2.95; P = 0.0046) and death (hazard ratio, 2.74; P = 0.0086).
The nuclear presence of survivin may be an independent biomarker for disease recurrence and overall survival in patients with resected Stage I and II NSCLC. Cancer 2005. © 2005 American Cancer Society.

subset: commoncrawl


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7 Reviews
delicious and so easy to make! i love the coconut/chocolate/nut plavor. i didn't have macadamias so i used pistachios and peanuts, they tasted great.
These didn't work for me, and it's probably my fault. I could't find chocolate wafers so I substituted Oreos -- huge mistake! They were greasy, way too sweet, and I literally ad to chisel them out of the pan. I'm sure these are good when made with chocolate wafers though.
We call theese congo bars.
Made a double batch for a large group. I used chocolate wafer cookies and put in food processor to make crumbs. I think oreos would also work well. The recipe is very easy and tastes great. Can't wait to serve them to the group.
Loved this recipe! It was very easy and very good! I'll keep making these for a long time to come.
My life is complete now! This was incredible! Thanks!
OMG!!! Love4...these bars are totally amazing... I had frozen Macadamia nuts in my freezer leftover from Christmas and I was looking for someway to use them...I made this with my homemade sweetened condensed milk...made just as directed no changes...these are very decadent, and very habit forming...so delicious...another winner, thanks so much for posting sweets


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"Justice League": Exploring How Superman Returns (Again)
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Dark Horse has provided previews of titles on sale this week, including Torajiro Kishi's "Devil" #2, "Groo: Hogs of Horder" #4, and "Turok: Son of Stone" Archives vol. 5!
The recently exclusive DC superstar offers up his first interpretation of the Dark Knight for the hero's milestone 700th issue, which remains the only creative announcement surrounding the June-shipping book.
Marvel finishes out the week with two more students enrolling in "Avengers Academy's" summer session. Coeds Finesse and Hazmat will be a part of the June-launching series written by Christos Gage and illustrated by Mike McKone.
Courtesy of Zenescope Entertainment, CBR presents an exclusive First Look at the covers for the 50th issue of the publisher's "Grimm Fairy Tales," featuring artwork by Angel Medina, Franchesco and Al Rio.
Courtesy of Marvel Comics, CBR brings you advance looks at new comics on sale next Wednesday, March 17, including "Dark Avengers" #15, "Hercules: Fall of an Avenger" #1, "Siege" #3, the return of Doop in "Nation X" #4, and many more!
Courtesy of Marvel Comics, CBR presents an exclusive preview of "Hulk" #21, featuring the latest chapter in "Fall of the Hulks" as presented by Jeph Loeb and Ed McGuinness. The issue smashes into stores next Wednesday, March 17.
Marvel introduces Fortress to the swelling roster of students enrolled in this June's "Avengers Academy" via a new teaser image. The series launches in June from the creative team of Christos Gage and Mike McKone.
"Blackest Night" #7 leads direct market in a weak February! More on Fantagraphics' manga line and First Second's webcomics! San Diego's love-hate relationship with Comic-Con! Plus much more!
Reptil will be having his picture taken for the "Avengers Academy" yearbook as the "Avengers: The Initiative" character graduates to the new title by Christos Gage and Mike McKone. "Avengers Academy" opens its doors in June.
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INDIA: Remy and Highland cede control of Indian operations
Remy Cointreau and Highland Distillers have ceded control of their loss-making Indian operation DCM Remy to Indian company DCM Shirman Industries (DSIL), their partner in the Indian market.DCM Remy is a 50:50 venture between DSIL and HRI Mauritius, a company floated jointly between Highland Distillers and Remy Cointreau.According to Indian sources the move could be a precursor to the two overseas partners selling out altogether, although a decision has not been reached to this effect.The change in control involves the resignation of the three Highland Distillers and Remy Cointreau nominees on the six-member DCM Remy board. Furthermore, Dinesh Jain, Remy's nomination to the board and the CEO of the company, has also resigned to be replaced by a DSIL nominee.Indian press reports have stated that the new agreement drawn up between the partners will mean that DCM will only be able to sell one Highland brand - Black Bottle - for another three years. The other two brands the foreign partners bought in, Passoa and Cointreau, have been discontinued.According to the Indian source the move was the consequence of a joint agreement between Remy and Highland. They did not want to get into the Indian made foreign liquor segment, which was the area identified for growth by DCM in the future.
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List all words ending with fenthion
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Posted: March 5th, 2009
"We're extremely low-maintenance, we move fast"
Interview & Photo by Lee Bender
When you're young and all you've got is skateboarding, friendships, and music, there seems to be those one or two special bands that pull everything together—from single songs on broken mixtapes to full discographies on repeat through the night. With his song titles etched in griptape and his raspy recorded voice, Chuck Ragan——formerly of Hot Water Music and Rumbleseat—delivers music that's more than driving and more than personal, often about simple subjects that are not only uplifting but real as well.
What did you grow up listening to and reading?
I was born and raised in the Southeast of the US with a Southern Baptist background, alongside my brother Paul. Growing up that way was fine until we reached the age to actually think and decide for ourselves. When those decisions were "out of bounds" as they sometimes were, there was a definite clash. So early on, I always found music through rebellion. Or vice versa. Much of the music in our household and communities were old-time standards like bluegrass and gospel. I enjoyed the harmonies and energies from time to time, but was never in search of it. We moved to Lafayette, LA from Chattanooga, TN in 1985e. Freestyle bikes were out and skateboarding was huge, at least to us and where we lived. We found riding and the music that went with it to be exhilarating beyond belief, and from then on were changed for good. Back then it was bands like GBH, Bad Brains, Germs, Metallica, Creedence Clearwater Revival, and every song on every skate video we ever owned. The music then somewhat scared me. The same with riding. It was foreign and risky at that age and there was always something about it that I could relate to or make sense with. To say the least, I became very much so attached to it.
How soon after you discovered this did it take for you to become more involved with making music?
We moved to Sarasota, FL shortly after our move to Louisiana. I had a guitar then, but it collected dust mostly. I was way more interested in being outside. I did play in some bands and tried to learn the best I could, but it wasn't ever easy. My parents were trying to protect me from getting wrapped up in something dark and negative. At the time I thought they were crazy, but getting older now I can certainly see what frightened them about me and the crowd I was running with. I was reckless and sometimes dangerous, and they blamed the music. I'll agree now that it did add fuel to the fire. I have a great friend by the name of Christian Prather who taught me how to play a barre chord and do homemade tattoos. In those days if we weren't skating, we were inside skipping school, eating MoonPies, drinking RC Cola, giving each other tattoos, and learning Misfits songs. I still think we're all lucky to be alive.
Did you ever think playing music would lead to all of the traveling, and becoming the tight-knit family that it did?
I had no idea and never expected anything of the sort. The majority of the people that I know and love I've met through music. For me it's just a testimony that I was blessed enough to be involved within a community of people who really cared about what we were doing, as well as cared for one another. At least from my perspective. Don't get me wrong, I don't want to make it sound like it's all or was all a bunch of roses and cream. It was growing up and as most of us know, growing up can get excruciatingly messy. I think most families can be dysfunctional at times. The travelling as well was something that I had never dreamed it would be. It was amazing seeing all new places for the first time over land and seas and everywhere in between. As years pass, and you become familiar with the gas stations, clubs, rest stops, hotels, and telephones, the perspective changes. When you get out of a Sprinter in the middle of Bavaria, take one look around and know exactly where you are, where the phone and bathroom are, you change a little. All in all though, we did the best we could and took pride in what we did to get to the point where we are now. The answer is no way, I never thought it would become the family that it is now, but I'm very thankful.
Did you grow up with anyone that skateboarders could connect with these days, or in a past generation of skateboarding?
The skaters that I grew up with an admired the most were all friends. Nowadays they're graphic artists, contractors, writers, or musicians. There were always some great guys out there that I always wanted to skate next to and try to keep up with. The key was to find somebody better than you were to learn what they had to offer. In Lafayette, the Richard family owned a skateshop which was the coolest thing in the world at the time. Still is, really. Our friend Carl's mom and dad were always supportive, either building ramps or taking us hooligans around town to new spots. They bought and opened a shop and put on a demo in the parking lot. We had a big contest and they flew out Mike Vallely. Again, this was late '80s. I remember six or seven of us kids, maybe more, piling into Carl's mom's van to go pick him up at the airport. Mike stepped out of the plane door with a backpack and a skateboard. He looked around, put his trucks on the handrail for a 50-50 and walked down the stairs. When we saw that, we all exploded! Screaming, laughing, and wrestling until we fell down in the airport. Kids are funny. Needless to say, Mike made a huge impression on us, from new tricks to actually taking it seriously and answering our hundreds of questions. I saw him some time ago in LA at an Against Me! show. He was walking away and I stopped him to tell him a little about that time and to thank him for the years. I don't think I could ever really do it justice, though.
Do you still roll?
No question. I can't go as fast or as big as I once did, and the bones and joints aren't what they were some years ago, but I love it. I only ride transition nowadays, and mostly concrete. Not much street skating unless I go pick up our mail or bring the recycling down the road. You're definitely not as risky when you grow up, kids, so enjoy those handrails now!
Where did the name Hot Water Music come from?
We got the name from an old Charles Bukowski short story book. It made sense at the time and just stuck. There was another band called that at one time and we battled their label over the name for quite awhile. At one time we offered to wrestle for it, but they didn't find that too amusing or professional.
Compared to being a part of a family like Hot Water Music, how is it being on more of a solo kick?
Not as different as you would think except there's a hell of a lot less prep time, worry, stress, and drama. Less people equals less all of that. It's usually Jill and I on the road together, along with our fiddle player Jon Gaunt. We're extremely low-maintenance, we move fast, we decide fast, and eliminate a lot of waiting-around time the best we can. Jill has managed everything for the solo tours and does an incredible job, coming from a film production background where they're quite a bit more strict than in the music business. So we still have a family feel, just a bit more close-knit. We still deal with many of the same promoters as HWM did, and many of the same venues.
You mentioned that you and your wife have started your own record label. Did the DIY attitude come from your youth?
We just began our little mom and pop label that we're calling Ten Four Records. We're getting ready to kick off a new webstore over at Chuckraganmusic.com where we'll be putting up limited releases, shirts, and other swag. We always thought it would be cool, but had no idea that it would be happening now. As far as the DIY approach, it just seems right. We're far from finished with working with other labels, though. I'm in the early stages of writing for the next Side One Dummy release, which I'm more excited for than ever. This little label should be fun though, and hopefully will bring in enough to enable me to continue writing music and releasing random records of all sorts in the future. You never know until you give it a shot. We'll do our best!
Download Chuck Ragan from the iTunes store here.
Burger Boogaloo 2016 PhotosBurger Records took over Mosswood park in Oakland, CA, for their annual Boogaloo. The line-up was stacked, the sun was out and good times were had. Check out some photos here.
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Zig Zags' "Giving Up The Ghost" Music VideoZig Zags are back at it again with their heavy metal horror themed skate punk in the video for "Giving Up The Ghost" off the album, Running out of Red, out now on Castle Face records.
Suicidal Tendencies x Mob GripMob is proud to announce the latest collaboration with Dogtown's finest, Suicidal Tendencies.
Nas InterviewNas took the time to talk a little bit about his new projects and the New York state of mind.
Hanni El Khatib's "Mangos and Rice" Music VideoKeith Hufnagel's never before seen footage in Hanni El Khatib's newly released "Mangos and Rice" music video. Check it out.
Punk Rock Bowling AshburyPunk Rock Bowling takes over Ashbury Pary in New Jersey this weekend. Check out the line-up here.
Meltasia Music Festival 2016Here's your chance to live like a free roaming animal in an abandoned zoo and see tons of rad bands. Check it out.
Mix Master Mike InterviewDespite his crazy schedule, Mix Master Mike had some time to discuss groupies, memorable shenanigans with MCA and manifesting your destiny.


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Google Summer of Code 2006 a Success
The projects are in and the mentors have filed their evaluations. In the final tally, it looks like Google's Summer of Code 2006 was a success.
The program, having just finished its second year, provides funding to students and open source organizations for project development.
In 2005, Google accepted 410 projects. In 2006, Google's Summer of Code accepted a whopping 630 projects spread across 102 mentoring organizations. In 2005, there were only 41 mentoring organizations.
Each student who successfully completed their projects over the summer were to receive $4,500 from Google, while each open source organization was to receive $500 per successful student.
Leslie Hawthorn, open source program co-coordinator at Google, told internetnews.com that the program had an 82 percent overall success rate in 2006.
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It's great that Google
It's great that Google values open source. This is a way to help the community and at the same time run the business with the opportunity of advertising and recruitment. The student participants get a chance to explore their potentials and work on their ideas. They also have that kind of exposure that allows them to interact with the higher figures of the industry. This definitely beats a summer job at the burger joint.
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Servo Night Builds Begin, Linux Packages Coming
The Mozilla developers working on the Servo browser layout engine and the Browser.html HTML-based web UI have kept to their goal of making a tech preview available in June. As of last night, the Servo developers hit their tech preview milestone we've been looking forward to seeing for months. Nightly builds of Servo and Browser.html have begun and they are going to be making available Linux packages shortly.
Android Leftovers
Leftovers: OSS


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"One of the fastest growing universities in Egypt"Education expert Ahmed Hamad, President of the British University of Egypt, shares his views on the education sector in the country How is BUE positioned as an educational leader? Starting from our inauguration about 10 years ago, BUE has ... Khaleej Times, 20 minutes ago
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DU to redraft guidelines for ad-hoc appointments
Following protests from teachers against new rules announced by Delhi University for ad-hoc appointments, the varsity has now decided to redraft the guidelines. The varsity had sent a communication to all colleges and departments last week ...Business Standard, 25 minutes ago
Scientists at Junagadh Agricultural University find gold in urine of Gir cows
The famous Gir cows urinate gold, almost literally. After four years of extensive research, scientists of the Junagadh Agricultural University have (JAU) have found traces of gold in the urine of Gir cows. After analyzing urine samples of 400 Gir ...Meri News, 21 minutes ago Gold found in Gir cow urine: Junagadh Agricultural University Scientists New Indian Express, 2 hours ago Junagadh Agricultural University scientists find gold in Gir cow urine Economic Times, 6 hours ago
Ex-Pak President Zardari slams Imran Khan for allocating Rs.300 million to University of Jihad
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Lyrics Depot is your source of lyrics to MR. SOUL by Neil Young. Please check back for more Neil Young lyrics.
MR. SOUL Lyrics
Artist: Neil Young
Oh, hello Mr. Soul, I dropped by to pick up a reason
For the thought that I caught that my head is the event of the season
Why in crowds just a trace of my face could seem so pleasin'
I'll cop out to the change, but a stranger is putting the tease on.
I was down on a frown when the messenger brought me a letter
I was raised by the praise of a fan who said I upset her
Any girl in the world could have easily known me better
She said, You're strange, but don't change, and I let her.
In a while will the smile on my face turn to plaster?
Stick around while the clown who is sick does the trick of disaster
For the race of my head and my face is moving much faster
Is it strange I should change? I don't know, why don't you ask her?
Neil Young Lyrics
More Neil Young Music Lyrics:
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Man complains to police about prostitute price hike
In this photo taken Monday Jan. 10, 2011 a prostitute advertises her wares behind red-lit windows in Amsterdam, Netherlands. Saskatoon council is voting on a bylaw that would allow escort agencies and massage parlours to set up in specific areas. (AP Photo/Peter Dejong)
Published Friday, August 31, 2012 1:10PM EDT
Last Updated Friday, August 31, 2012 9:59PM EDT
ANN ARBOR, Mich. (AP) -- Police in southeast Michigan say a man called to complain that a woman he had agreed to pay for sex unexpectedly increased the price.
AnnArbor.com reports that police were called to an Ann Arbor home late Wednesday on a report of a robbery. Police say the 45-year-old man and a 19-year-old Ohio woman he contacted online had agreed on a price, but that the man claimed she upped the cost after taking his money.
Police say the woman was arrested. The man wasn't taken into custody.
According to investigators, the man and woman gave vastly different accounts of what happened. The case is under investigation and prosecutors will determine any possible charges.
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Ex-Duck McElhinney shuts out Admirals
Curtis McElhinney, who has bounced around since he was traded by the Ducks nearly two years ago, made 35 saves against his former team's top minor-league affiliate Sunday in leading the Springfield Falcons to a 5-0 victory over the Norfolk Admirals.
McElhinney, 29, also shut out Connecticut on Friday and now has a 1.29 goals-against average, a .955 save percentage and four shutouts in 10 games for Springfield, the American Hockey League affiliate of the Columbus Blue Jackets.
The Blue Jackets acquired him from Phoenix last February in the Antoine Vermette trade. McElhinney went 11-10-3 in 31 games with the Ducks over the 2009-10 and 2010-11 seasons but was dealt by Anaheim to Tampa Bay in February 2011 after several ragged performances in place of the ailing Jonas Hiller.
Norfolk (6-5-0) has dropped three games in a row as it caps a four-game road trip Monday at Albany against the Devils. Struggling goalie Igor Bobkov was pulled after one period for the second consecutive night as he allowed four goals on 12 shots.
Nick Drazenovic scored twice while Matt Calvert, Jonathan Audy-Marchesseault and Cam Atkinson also added goals for the Falcons.
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Impressed (X20) :-)
Started Apr 11, 2014 | Discussions thread
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D200_4me • Veteran Member • Posts: 3,875
Impressed (X20) :-)
Apr 11, 2014
Just got my X20 yesterday. I don't have a gallery of images yet, but I did do a quick set of ISO test photos. I have to say, I'm very happy with the performance for a company camera. The test photos are here: http://www.openbloom.com/Other/Fuji-X20-Test-Photos/n-cPFCQ/
Some other shots I took outside yesterday at low ISO were very sharp, detailed and very clean. Better than any point and shoot I've used with this type of a small sensor (or smaller).
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Can Huawei Redefine the Smartphone?
At Huawei's tenth annual Global Analyst Summit, the company shared its plans to conquer the smartphone market, taking down Apple and Samsung along the way.
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Eating In
Vegan or Bacon?
Brussels sprouts swing both ways
By Ari LeVaux
Brussels sprouts with bacon is hardly a new idea, but the combination has taken off lately. Now the pairing is a menu meme, a darling of online recipe searches and food TV. But those green brassica balls also go effortlessly and deliciously, for example, in that most vegetarian of dishes: the leafy salad.
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Two restaurants reach the decade mark
By Christie Chisholm
Annapurna and Thai Crystal celebrate ten years of dishing.
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34 Holiday Ideas for Gifts in a Jar
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Christmas Snow Globe
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Caixin OnlineOpinionEditorial The Limits of State Capitalism
The Limits of State Capitalism
Amid much discussion of China's economy, this much is clear: It has gone as far as it can in its current form
In today's international debate over China's development model, a commonly heard term is "state capitalism,' and one oft-cited example of this is the country's development of high-speed railways.
Yet, in this issue of Caixin we report on exorbitant prices paid for bathroom fixtures on new bullet trains, further evidence if any were needed of the ills of state-led market development. In light of such abuses, a closer look at state capitalism is timely.
- CIC Announces Appointment of Shanghai Vice Mayor as General Manager
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- Shanghai Cracks Down on Illegal Capital Flight
- Unseen Opportunities Created by 'Brexit'
- Points to Ponder when Building China's Future Megalopolis
- Closer Look: Putin's Latest State Visit Highlights Mutual Interests with China
- Shenzhen Bourse Queries Vanke's Hostile Suitors
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- Chinese High Speed Rail Builder Doubts U.S. Partner's Sincerity
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- Investor Pain over Mobile Medical App Strain
- Intensifying Battle over Who Controls Vanke
- Two Top Chinese Steel Makers to Reorganize, May Merge
Latest Issue
On the Cover:
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Issue 102
June , 2016


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This page contains Virtual Villagers 3: The Secret City Hints for PC called "Hint to make food faster" and has been posted or updated on Dec 5, 2012 by Ery.
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At this year's NAB convention, Scientific-Atlanta will showcase new solutions and products designed to help cable operators and broadcasters squeeze more performance from networks to expand services to customers and create new revenue opportunities.
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Rob Burnett Makes a Laugh-Out-Loud Dramedy with 'The Fundamentals of Caring'
New Lifetime Docuseries Focuses on Families of Olympic Hopefuls
FAA's New Drone Rule Gets Mixed Responses


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argv I have to type the file as an argument (ex:
python ex15.py ex15_sample.txt) and when using
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"Airstrip Titty Connoisseur? Damn Rat!" is an anagram of Transport Security Administration.
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When the damned things were nicknamed "pornoscaners" it was done without a lick of sarcasm. Plenty of derision, but absolutely no sarcasm.
I'm surprised there aren't galleries out there yet.
When they first came out, one of the top Bollywood stars found that the security had printed out his pornoscan. I guess he saw a publicity opportunity, because instead of raising hell, he signed copies of it for them.
I'm surprised there aren't galleries out there yet.
You need to spend more time on 4chan.
"You need to spend more time on 4chan."
Now that's advice I never thought I'd see in any context.
Well duh!
From TFA:
"All of our millimeter wave technology units including those in Dallas have been upgraded with additional privacy enhancements that no longer display passenger-specific images," the TSA said in a statement. "To further ensure passenger privacy and anonymity, a privacy filter was applied to blur all images."
Talk about Security Theatre. They've blurred all images and now don't display passenger-specific images. So these scanners are now even more obviously bloody useless than they were before?
It is not clear from the article if the scanner had the privacy upgrades done before or after these incidents. If after, the upgrades may have been in response to these types of complaints. Good.
If the upgrades were done before, it is quite possible she was being sent through repeatedly for exactly the reason you suspect, and not because of any interest on the part of the screener. The "I'm letting her go" comment from the agent may have been due to the lines backing up or the passenger getting agitated.
I've seen those "privacy enhanced" scans in person: Last time I flew to Las Vegas, BWI and McCarran both had it. The image is a generic body outline with boxes indicating areas of unusual density (which is what these scanners are supposed to detect). You can't see anyone's junk, but at the same time you don't get a clear picture of what the scanner is alerting on.
It works exactly like the TSA's info page says it does: (zoom in on the page, it is displayed smaller than actual size) http://www.tsa.gov/approach/tech/ait/privacy.shtm
A lot of the scanners that do this type of scan have the monitor right on the side of the scanner so the agent putting you through is the one that reviews it. So the result is that some agents will send a person through more than once before patting them down in those specific areas. You'd be surprised on what false alarms: For some reason I always seem to get checked under my arms, and women with big hair seem to get patted on the head quite often.
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|By John Cowan
Article Rating:
|February 27, 2012 05:00 AM EST
Abstract: This is Part II in a blog series by 6fusion Co-founder and CEO John Cowan on the emerging trend of Cloud Brokerage and the impact it will have on the technology industry and markets. Be sure to check out Part I of the series here.
Part II – The Cloud Vendor and the Agnostic Intermediary
I gave a presentation a few months back in which I opened with the following statement: The future of cloud computing has little to do with technology. Sounds crazy, right? But before you send me to the virtual nuthouse, let me explain.
What I think is unclear in the emerging Cloud Broker business model is the demarcation point between the business of compute and the technical organization of compute. The era of Cloud Brokerage will see these two concepts treated and considered as two distinct threads. The technical organization of compute is what the myriad of cloud software vendors does today. They are the companies that pitch "hey, buy my software and you too can have a cloud" or "hey, run your apps on our infrastructure and you too can pay for IT like a utility." The role of this vertical in the industry is about the orchestration and management of the compute resources sitting in customer cabinets and cages across the global data center landscape. It is about, as some of the more vocal pundits and talking heads espouse, a complete paradigm shift in the way IT is delivered.
But cloud vendors, despite their impressive efforts to convince us otherwise, are, and never will be, Cloud Brokers.
Cloud Brokers will focus on the business of compute rather than the technical organization of compute. And the business of compute has nothing to do with cloud computing or the technology driving this revolution. The business of compute is about the commoditization of compute, network and storage infrastructure.
There is a big difference.
Analysts and experts measure the market by examining the adoption rates of cloud technologies private and public. Projections vary widely but I think we can all agree we are already in a Total Addressable Market (TAM) in the billions and on a fast track much higher.
That's a lot of dough. But the real TAM for Cloud Brokerage is much, much bigger.
Cloud Brokers will play a catalyzing role in the establishment of a commodities market for computing, just like soybeans, metals or corn. One of the principal advantages of any commodity market is for businesses to hedge their risk. It is difficult to argue that such practices could not or should not extend to information technology needs (specifically computing).
In order to truly see this market one must look beyond the resources that are "in the cloud" today. Businesses in the future will hedge their total risk – the needs of the organization both internally and externally. That is – the sum total demand for compute resources. To this end, existing market sizing reports dealing with cloud are inadequate to represent the total opportunity. Based on publically available data on server and storage shipment tracking I believe the TAM for Cloud Brokerage to be north of $1 Trillion.
As a central figure to the emergence of a commodity market for compute infrastructure, the Cloud Broker must be an entirely agnostic intermediary. The job of the agnostic intermediary will be to connect those that consume infrastructure and those that produce infrastructure. It will not be their job to influence, direct, sell or support what the infrastructure is ultimately used for. Nor will it be their job to influence what infrastructure supplier is used.
Herein lies the demarcation point between those facilitating the future business of compute and those enabling the technological organization of compute.
This may come as a revelation to some, but it won't be players like Amazon, Rackspace and the 'Magic Quadrant' of telcos and co-lo providers that form the commodity market for compute. Yes, they will no doubt be suppliers to the market. But they will not be the true market makers.
Today's leading cloud vendors will learn that you can't be a retail cloud and an intermediary for a cloud market. The very concept would be like being an arms dealer for the war in which you take up arms. It will not work. While important actors in the emerging story, today's cloud vendors are merely proving out that there is room for many suppliers in the market.
In Part III of this post I will take a look at the some of the important technologies that will emerge to create what I call "The Market Unified."
SYS-CON Events has announced today that Roger Strukhoff has been named conference chair of Cloud Expo and @ThingsExpo 2016 Silicon Valley. The 19th Cloud Expo and 6th @ThingsExpo will take place on November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. "The Internet of Things brings trillions of dollars of opportunity to developers and enterprise IT, no matter how you measure it," stated Roger Strukhoff. "More importantly, it leverages the power of devices and the Interne...
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Cloud Expo, Inc. has announced today that Andi Mann returns to 'DevOps at Cloud Expo 2016' as Conference Chair The @DevOpsSummit at Cloud Expo will take place on November 1-3, 2016, at the Santa Clara Convention Center in Santa Clara, CA. "DevOps is set to be one of the most profound disruptions to hit IT in decades," said Andi Mann. "It is a natural extension of cloud computing, and I have seen both firsthand and in independent research the fantastic results DevOps delivers. So I am excited t...
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Apixio Inc. has raised $19.3 million in Series D venture capital funding led by SSM Partners with participation from First Analysis, Bain Capital Ventures and Apixio's largest angel investor. Apixio will dedicate the proceeds toward advancing and scaling products powered by its cognitive computing platform, further enabling insights for optimal patient care. The Series D funding comes as Apixio experiences strong momentum and increasing demand for its HCC Profiler solution, which mines unstruc...
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The Internet of Things will challenge the status quo of how IT and development organizations operate. Or will it? Certainly the fog layer of IoT requires special insights about data ontology, security and transactional integrity. But the developmental challenges are the same: People, Process and Platform and how we integrate our thinking to solve complicated problems. In his session at 19th Cloud Expo, Craig Sproule, CEO of Metavine, will demonstrate how to move beyond today's coding paradigm ...
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Internet of @ThingsExpo has announced today that Chris Matthieu has been named tech chair of Internet of @ThingsExpo 2016 Silicon Valley. The 6thInternet of @ThingsExpo will take place on November 1–3, 2016, at the Santa Clara Convention Center in Santa Clara, CA.
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The cloud market growth today is largely in public clouds. While there is a lot of spend in IT departments in virtualization, these aren't yet translating into a true "cloud" experience within the enterprise. What is stopping the growth of the "private cloud" market? In his general session at 18th Cloud Expo, Nara Rajagopalan, CEO of Accelerite, explored the challenges in deploying, managing, and getting adoption for a private cloud within an enterprise. What are the key differences between wh...
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UAS, drones or unmanned aircraft, no matter what you call them — this was their week. Our news stream was flooded with updates on the newly announced rules and regulations for commercial UAS from the FAA. So, naturally we have dedicated this week's top news round up to highlight some of our favorite UAS stories.
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Basho Technologies has announced the latest release of Basho Riak TS, version 1.3. Riak TS is an enterprise-grade NoSQL database optimized for Internet of Things (IoT). The open source version enables developers to download the software for free and use it in production as well as make contributions to the code and develop applications around Riak TS. Enhancements to Riak TS make it quick, easy and cost-effective to spin up an instance to test new ideas and build IoT applications. In addition to...
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Belk gives work by famous sculptor to commemorate new swimming programs
Irwin Belk gives Jon Hair sculpture to Queens University of Charlotte
Bronze sculpture of a woman diving celebrates new swimming programs
Queens benefactor Irwin "Ike" Belk recently donated a sculpture to Queens University of Charlotte to commemorate the addition of swimming programs.
The sculpture is by artist Jon Hair who also created "Rex," the largest standing lion sculpture in the world which stands at the Queens Sports Complex on Tyvola Road.
"As a former athlete I'm so pleased to see Queens add swimming to its athletics programs and look forward to watching those teams develop," said Belk, who is a former member of the
U.S. Olympic Committee.
The sculpture is now showcased in the office of Queens President Pamela L. Davies who said she's inspired by the graceful form of the female swimmer bending into a back dive.
The gift enhanced the campus-wide celebration about the new programs, said David Marsh, Queens' executive in residence for athletics and high performance.
Sculptor Hair lives at Lake Norman and has earned worldwide acclaim for his massive bronze sculptures at Queens and several other universities, at the U.S. Air Force Academy, Olympic Training Center, in front of Merrill Lynch in Manhattan, and other notable locations.
Queens University of Charlotte is a private, co-ed, Presbyterian-affiliated comprehensive university with a commitment to both liberal arts and professional studies. Located in the heart of historic Charlotte, Queens serves approximately 2,600 undergraduate and graduate students through its College of Arts and Sciences, the McColl School of Business, the Wayland H. Cato, Jr. School of Education, the School of Communication, Hayworth College for Adult Studies and the Andrew Blair College of Health which features the Presbyterian School of Nursing.
Office of Marketing & Community Relations
Queens University of Charlotte
1900 Selwyn Ave.
Charlotte, NC 28274
|Media Contact:
Lisa Noakes
704 337-2452
|Royals Athletics Contact:
Sarah Waple
- Queens Ranked A Best College for Veterans
- STARTALK Summer Program Offers High Schoolers Language Immersion Opportunities
- Faculty-Student Project Produces, Fires Wood Kiln
- Queens Military Students Welcome General Pace, Veterans to Campus
- Dr. Perkins, Queens Students Work with Community to Improve Water Quality
- Communication Student Wins 2016 Outstanding Journalism Award
- MFA Faculty, Alumni Continue Success
- History Students Receive Awards on Research
- Queens Announces Cherie Swarthout as Director of Athletics
- MFA Residency Welcomes Talented Faculty and Students, Congratulates Graduates


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Oscar nominees have to go through a host of interviews before the big night and some are more fun than others. Hangover star Zack Galifianakis has brought the art of the very awkward interview to perfection in his FunnyOrDie series Between Two Ferns.
The actor took the chance to get Jennifer Lawrence, Christoph Waltz, Naomi Watts, Anne Hathaway between his two ferns after the Oscar luncheon last week.
Enjoy this feast of awkwardness:
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Coldplay's Chris Martin got his kids up on stage at Glastonbury to help with a track
Tomas Ford: The DJ who proudly plays all the crap music
Lindsay Lohan and Russian boyfriend make their red carpet debut
TVNZ Breakfast: Sam and Rawdon gag while eating a dried centipede
Comedian destroys sexist heckler in epic takedown
Kiwi actress Kimberley Crossman talks working with Shatner and Smith on E!'s Hashtaggers
The Kardashians are not happy about brother Rob Kardashian's engagement
How Grey's Anatomy star Jesse Williams dominated the BET Awards
Channing Tatum says Stanford swimmer Brock Turner's leninent sentence is 'not right'
Backstreet's Zombie Western trailer drops
Lena Dunham is very disturbed by Kanye's Famous video
Toilet trouble on Breakfast show
Dead man found in cardboard bale at Hamilton business
A building that houses a five-star cat motel in Hamilton is on the market
Moko's killers: Tania Shailer went from mother to killer, overnight
Police find pair from fatal crash mystery car
Hamilton shop's decision to give away free pregnancy tests raises ethical debate
University of California's closer ties with Waikato
Couple hospitalised after car hits power pole
Firearms targeted in rural burglaries
Transforming Hamilton: Steve Hart has his say
School holds special place for principal
Funds squeeze hurts cancer patients
Top five things to do this weekend
Waikato trio succeed despite big setbacks
Police find people from fatal crash mystery car
The top tenth of Kiwis hold well over half of New Zealand's wealth
New Zealander dies after being hit by truck in California
Body found in cardboard bale at Hamilton business
Armed police attend incident in Lower Kaimai, Bay of Plenty
Moko's mum: 'It was premeditated murder'
Masked man scared away after threatening a Hamilton dairy
Gym members fume as doors shut at Hamilton Configure Express
Rumours over Tania Shailer being stabbed in prison untrue - Corrections
Daniel Viliami denied parole 14 years after murdering girlfriend
What happens when a gym shuts and you've paid for a 12 month contract?
'Jigsaw' of movements prior to crash that killed four young people


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Utility EDF Guarantees Supermarket $1.6m Efficiency Savings
Morrisons, one of the biggest U.K. supermarket chains, has struck an unusual deal with its energy provider: utility EDF has guaranteed the grocer savings of £1 million ($1.64 million) a year.
The two companies yesterday announced a three-year contract under which EDF Energy guarantees that its energy-efficiency programs will save Morrisons at least that much, Business Green reports. And the contract also contains incentives to encourage the utility to save Morrisons even more.
"Our energy services team will work hand in hand with the Morrisons Property and Development Department on project delivery, with an aim of saving at least £3.5m during 2011 through new energy-saving initiatives." said Sid Cox, director of business to business at EDF.
The two companies agreed that they will co-operate to improve Morrisons' energy procurement to better manage volatility in wholesale markets, and they also promise to support the design of more energy-efficient stores. They will also work to develop a staff energy-efficiency awareness campaign.
Morrisons has a goal of cutting carbon emissions by 30 percent by 2020, Business Green said.
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Dean Ambrose Gets Stitches After RAW (Photo), Ambrose-Renee Young Dating?
– As seen on Monday night's edition of RAW, Dean Ambrose suffered a pretty bad cut under his chin during the main event of the show. According to the official WWE website, Ambrose required nine stitches to close the wound. You can check out a photo of Ambrose getting stitched up below.
– Speaking of Ambrose, according to a recent article in the UK-wrestling magazine "Power Slam," Ambrose and WWE interviewer Renee Young may be dating. The publication wrote the following:
"One of our spies spotted Renee 'Young' Paquette and Jonathan 'Dean Ambrose' Good "looking very chummy together" on King Street in Toronto on the afternoon of May 8."
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There are 4 Comments
young looks chummy with everyone
He's a big boy, its just a scratch for him. If Dean and Young are truly a couple then kudos to him.
I have a feeling friends w/ benefits is a better definition of what they have. He's not shy admitting he enjoys the company of women. She's a huge fangirl of several of the WWE & eye bangs them all during interviews…. Surprised dirt sheets are just catching up to this… rumours have been circulating since late 2013…