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Publications (20)48.84 Total impact
- [Show abstract] [Hide abstract] ABSTRACT: Syndromes with focal overgrowth are sporadic diseases and comprise Proteus syndrome and congenital lipomatous overgrowth, vascular malformations, and epidermal naevi (CLOVE) syndrome, and isolated hemihyperplasia. We describe 3 children classified according to standard criteria with dysregulated growth of various tissues that was excised, together with excess toes, and tumours. Correct classification facilitates diagnosis and operations. Interdisciplinary treatment and follow-up are recommended to prevent disfiguration.
Article: Matrix metalloproteinase inhibition delays wound healing and blocks latent transforming growth factor-β1 promoted myofibroblast formation and function[Show abstract] [Hide abstract] ABSTRACT: The ability to regulate wound contraction is critical for wound healing as well as for pathological contractures. Matrix metalloproteinases (MMPs) have been demonstrated to be obligatory for normal wound healing. This study examined the effect that the broad-spectrum MMP inhibitor BB-94 has when applied topically to full-thickness skin excisional wounds in rats and its ability to inhibit the promotion of myofibroblast formation and function by the latent transforming-growth factor-beta1 (TGF-beta1). BB-94 delayed wound contraction, as well as all other associated aspects of wound healing examined, including myofibroblast formation, stromal cell proliferation, blood vessel formation, and epithelial wound coverage. Interestingly, BB-94 dramatically increased the level of latent and active MMP-9. The increased levels of active MMP-9 may eventually overcome the ability of BB-94 to inhibit this MMP and may explain why wound contraction and other associated events of wound healing were only delayed and not completely inhibited. BB-94 was also found to inhibit the ability of latent TGF-beta1 to promote the formation and function of myofibroblasts. These results suggest that BB-94 could delay wound closure through a twofold mechanism; by blocking keratinocyte migration and thereby blocking the necessary keratinocyte-fibroblast interactions needed for myofibroblast formation and by inhibiting the activation of latent TGF-beta1.
Article: Magnetic Resonance Imaging Monitoring of Peripheral Nerve Regeneration following Neurotmesis at 4.7 Tesla[Show abstract] [Hide abstract] ABSTRACT: The preoperative diagnostic imaging of peripheral nerve lesions and the postoperative monitoring of microsurgically coapted nerves remain unsolved problems. The aim of this study was to investigate peripheral nerve regeneration after complete neurotmesis with magnetic resonance imaging techniques. Study groups included 70 rats. Their right sciatic nerve was either cut and left untreated or epineurially coapted. After postoperative days 3, 6, 10, and 14 and then weekly until postoperative day 84, these rats underwent scanning at 4.7 T. T2 signal intensities of the nerves were analyzed. In parallel, on postoperative days 3, 6, 10, 14, 21, 28, 42, 63, or 84, rats were killed for histologic processing. These findings were related to the corresponding images. After an initial T2 signal increase of the nerves in both groups, the coapted group demonstrated a major T2 signal decrease in the distal part of the nerve after postoperative day 21, whereas in the unrepaired group a signal decrease was not observed until postoperative day 42. Differences between the two groups were significant at postoperative days 3, 6, and 28 and thereafter. The signal decrease in the coapted nerves could be correlated to the ingrowth of regenerating axons observed by histology. Moreover, the continuity of coapted nerves or an explicit gap in the unrepaired group was detectable at every time point. This study presents novel magnetic resonance imaging data regarding regeneration after neurotmesis. High-field-strength magnetic resonance imaging has the potential to diagnose a discontinuity within a nerve of interest and monitor its regeneration after coaptation.
Article: SYNTHETIC MATRIX METALLOPROTEINASE INHIBITIOR DELAYS WOUND CONTRACTION THROUGH REDUCED TRANSFORMING GROWTH FACTOR-beta 1 ACTIVATION
- [Show abstract] [Hide abstract] ABSTRACT: Vaginal reconstruction has been performed for more than a century. Main complications are vaginal stenosis requiring dilatation, dyspareunia, excessive mucus secretion, and poor aesthetic and functional outcome. Here we report a new operation method modified after Baldwin for intestinal vaginoplasty in a patient with pelvic exenteration after spinal cell carcinoma of the vagina. Because of balanced liquid resorption and mucus secretion with sufficient vessel length in the terminal ileum, this intestinal segment was chosen. A J-pouch of distal ileum was constructed pedicled on the ileocolic artery and accompanying nervous plexus, transferred into the lower pelvis and sutured to the vaginal stump. One year follow-up showed a highly satisfied, sexually active patient, with adequate vaginal size, optimal lubrication and no molesting fecal odor. Terminal ileum J-pouch vaginoplasty is an optimal method for vaginal reconstruction providing a sufficient vaginal lumen and lubrication and thereby restoring patients' sexual life and increasing life quality.
Article: Myopathic changes in bilateral hypertrophy of the first dorsal interosseus muscle of the hand[Show abstract] [Hide abstract] ABSTRACT: A 43-year-old healthy man presented with bilateral hypertrophy of the first dorsal interosseus muscles of both hands. Neurophysiologic and laboratory examinations revealed no pathologic findings. Doubled muscle width was found by ultrasound. Myopathic changes were present in muscle biopsy with varying fiber sizes but without inflammatory features. The clinical impression of massive bilateral symmetric enlargement of the first dorsal interosseus muscles was characterized by subtle, non-specific muscular pathology.
- [Show abstract] [Hide abstract] ABSTRACT: The purpose of this study was to evaluate the feasibility, quality, and possible future implications of magnetic resonance imaging (MRI) of the human hand and wrist at 7 T. Images of the left hand of a healthy volunteer were acquired with a 7- and a 1.5-T whole body system and comparatively analyzed. Axial and coronal two-dimensional gradient echo (GRE) images with inflow saturation, coronal 3D GRE images, and time-of-flight angiographies were obtained without averaging. Image details were related to the complex hand anatomy. With the 7-T protocols established in this study, high-quality and high-resolution images of the hand and wrist were obtained. In the 2D GRE images at 7 T, small anatomical structures of the hand were depicted in vivo with superior detail and resolution, compared to 1.5 T and published studies at lower field strength. Signal-to-noise ratios (SNRs) were approximately five times higher at 7 T compared to 1.5 T. Additionally, thin 3D GRE images with good quality of the whole hand were obtained in a short acquisition time. Moreover, time-of-flight angiographies of the small hand arteries have been acquired without the application of contrast agents. Seven-tesla imaging of the hand can be used in vivo with ultra-high resolution and sufficient SNR. It allows for exact delineation of most anatomical structures including nerves, muscles, tendons, ligaments, cartilage, and blood vessels.
- [Show abstract] [Hide abstract] ABSTRACT: The rectus femoris muscle flap is well known for its reliable anatomy, the ease with which it can be harvested, and its great versatility. As a pedicled or free flap, it is used to cover soft-tissue defects and to recreate motor function. Although the muscle is very reliable, it is not well respected because of its assumed donor-site morbidity, such as weakened knee extension force and decreased range of motion of the knee. To date, these clinical assumptions have only rarely been quantified in terms of objective scores, concerning force deficit and functional or aesthetic outcome. From 1995 to 2002, the authors treated 24 patients with pedicled rectus femoris muscle flaps. Fourteen patients were followed up. Follow-up time ranged from 3 to 56 months postoperatively. The results were evaluated by a standard questionnaire in which pain in relation to walking distance, subjective feeling of weakness, sensibility disorders, everyday function, and aesthetic aspects were assessed. Range of motion in the hip and the knee was measured. For objective verification of a decrease of maximal voluntary contraction force of the remaining quadriceps muscle and for detecting differences in true muscular capacity and voluntary activation, 10 patients with unilateral rectus femoris flaps were tested using the twitch interpolation technique. The authors' patients assessed the remaining function and the aesthetic result of the thigh as at least satisfactory. Two patients complained about pain and weakness in the thigh. Eight patients reported hypesthesia in the lateral suprapatellar region. The maximal voluntary contraction and true muscular capacity values were reduced by 21.8 percent and 18 percent, respectively, when compared with the healthy leg. The range of motion in the knee and hip was not influenced by muscle harvesting. The twitch interpolation technique revealed a mild voluntary activation deficit, probably caused by inhibitory regulation in the spinal cord. In conclusion, donor-site morbidity of the rectus femoris muscle flap is evident but well compensated. There is no decrease in active range of motion in the knee and hip. Patient satisfaction with the functional and aesthetic outcome was high.
Article: Host responses after acellular muscle basal lamina allografting used as a matrix for tissue engineered nerve graft[Show abstract] [Hide abstract] ABSTRACT: A nerve gap must be bridged by autologous nerve grafts that serve as scaffold and consist of viable Schwann cells that promote regeneration. Owing to the necessary immunosuppression, nerve allografts remain limited to special cases. Alternatively, tissue engineering of peripheral nerves focuses on the implantation of cultured Schwann cells into suitable scaffolds. We established grafts from Schwann cells and basal lamina from acellular muscles. These grafts offer a regeneration that is comparable to autologous nerve grafts. Using a rat model (DALEW.1W strain), the present study evaluates the host response to acellular muscle allografts by assessing cellular reaction major histocompatability (MHC) class I and II, lymphocytes, macrophages. The results were compared to untreated muscle allografts. Macroscopically, the untreated muscles showed a strong inflammatory reaction as a sign of rejection, whereas the acellular muscle offered only minor reactions in the periphery of the graft. Expression of MHC I and II and invasion of CD4/CD8 positive cells and macrophages was pronounced after grafting the untreated muscles. Only a moderate reaction was noted for these parameters after acellular grafting. The acellular muscle graft is not completely free of cellular response; however the reaction is considered to be moderate and is located only in the periphery. To date, synthetic scaffolds that represent endoneurial tube-like structures and allow sufficient adhesion of Schwann cells and axonal regeneration are not available. The decreased response to acellular muscle allografts offers at least a basis for further experiments.
Article: Influence of Insulin-like growth factor-I (IGF-I) on nerve autografts and tissue engineered nerve grafts[Show abstract] [Hide abstract] ABSTRACT: To overcome the problems of limited donor nerves for nerve reconstruction, we established nerve grafts made from cultured Schwann cells and basal lamina from acellular muscle and used them to bridge a 2-cm defect of the rat sciatic nerve. Due to their basal lamina and to viable Schwann cells, these grafts allow regeneration that is comparable to autologous nerve grafts. In order to enhance regeneration, insulin-like growth factor (IGF-I) was locally applied via osmotic pumps. Autologous nerve grafts with and without IGF-I served as controls. Muscle weight ratio was significantly increased in the autograft group treated with IGF-I compared to the group with no treatment; no effect was evident in the tissue-engineered grafts. Autografts with IGF-I application revealed a significantly increased axon count and an improved g-ratio as indicator for "maturity" of axons compared to autografts without IGF-I. IGF-I application to the engineered grafts resulted in a decreased axon count compared to grafts without IGF-I. The g-ratio, however, revealed no significant difference between the groups. Local administration of IGF-I improves axonal regeneration in regular nerve grafts, but not in tissue-engineered grafts. Seemingly, in these grafts the interactive feedback mechanisms of neuron, glial cell, and extracellular matrix are not established, and IGF-I cannot exert its action as a pleiotrophic signal.
Article: Reconstruction of peripheral nerves using acellular nerve grafts with implanted cultured Schwann cells[Show abstract] [Hide abstract] ABSTRACT: The bridging of nerve gaps is still one of the major problems in peripheral nerve surgery. The present experiment describes our attempt to engineer different biologic nerve grafts in a rat sciatic nerve model: cultured isogenic Schwann cells were implanted into 2-cm autologous acellular nerve grafts or autologous predegenerated nerve grafts. Autologous nerve grafts and predegenerated or acellular nerve grafts without implanted Schwann cells served as controls. The regenerated nerves were assessed histologically and morphometrically after 6 weeks. Predegenerated grafts showed results superior in regard to axon count and histologic appearance in comparison to standard grafts and acellular grafts. The acellular nerve grafts showed the worst histologic picture, but axon counts were in the range of standard grafts. The implantation of Schwann cells did not yield significant improvements in any group. In conclusion, the status of activation of Schwann cells and the stadium of Wallerian degeneration in a nerve graft might be key factors for regeneration, rather than total number of Schwann cells. Predegenerated nerve grafts are therefore superior to standard grafts in the rat model. Acellular grafts are able to bridge nerve gaps of up to 2 cm in the rat model, but even the addition of cultivated Schwann cells did not lead to results as good as in the group with autologous nerve grafts.
- [Show abstract] [Hide abstract] ABSTRACT: Clenbuterol is known to act as a neuroprotective substance in the central nervous system, and also reduces muscle atrophy after denervation. The aim of this study was to evaluate its influence on peripheral nerve regeneration. The rat sciatic nerve model was used in four groups (n = 8 per group). After complete nerve transection and microsurgical coaptation, two groups received a daily oral dose of 100 microg/kg clenbuterol and two served as controls. Regeneration was assessed clinically, histologically, and morphometrically after 4 and 6 weeks. The weight ratios of calf muscles were calculated. Histological examination showed significantly increased axon counts in the clenbuterol group and a better degree of myelination. Muscle weight ratios of the clenbuterol group were significantly increased after 6 weeks, and the animals showed improved function of the hindlimb. Thus, therapy with 100 microg/kg clenbuterol daily after coaptation of a sciatic nerve showed a positive influence on clinical, histological, and morphometrical parameters in the rat model. The underlying mechanism remains unclear.
Article: Tissue Engineering of Peripheral Nerves: A Comparison of Venous and Acellular Muscle Grafts with Cultured Schwann Cells[Show abstract] [Hide abstract] ABSTRACT: Bioengineering is considered to be the laboratory-based alternative to human autografts and allografts. It ought to provide "custom-made organs" cultured from patient's material. Venous grafts and acellular muscle grafts support axonal regeneration only to a certain extent because of the lack of viable Schwann cells in the graft. We created a biologic nerve graft in the rat sciatic nerve model by implanting cultured Schwann cells into veins and acellular gracilis muscles, respectively. Autologous nerve grafts and veins and acellular muscle grafts without Schwann cells served as controls. After 6 and 12 weeks, regeneration was assessed clinically, histologically, and morphometrically. The polymerase chain reaction analvsis showed that the implanted Schwann cells remained within all the grafts. The best regeneration was seen in the control; after 12 weeks the number of axons was increased significantly compared with the other grafts. A good regeneration was noted in the muscle-Schwann cell group, whereas regeneration in both of the venous grafts and the muscle grafts without Schwann cells was impaired. The muscle-Schwann cell graft showed a systematic and organized regeneration including a proper orientation of regenerated fibers. The venous grafts with Schwann cells showed less fibrous tissue and disorganization than the veins without Schwann cells, but failed to show an excellent regeneration. This might be attributed to the lack of endoneural-tube-like components serving as scaffold for the sprouting axon. Although the conventional nerve graft remains the gold standard, the implantation of Schwann cells into an acellular muscle provides a biologic graft with basal lamina tubes as pathways for regenerating axons and the positive effects of Schwann cells producing neurotrophic and neurotropic factors, and thus, supporting axonal regeneration.
Article: Neuroma[Show abstract] [Hide abstract] ABSTRACT: Schwann cells are used in combination with biological matrices as tissue engineered nerve grafts in animal models offering a new therapeutic approach for treatment of lesions of the peripheral nervous system. A high yield of human Schwann cells from adult donors is only achieved by pharmacological stimulation, which should, however, be avoided in clinical therapy. Here, we establish cultures of activated human Schwann cells which were isolated from peripheral nerve neuroma which developed after a median nerve lesion. To allow nerve reconstruction neuroma have to be resected. Such neuroma tissue is virtually predegenerated and shows activation of Schwann cells, implying good adherence and high mitotic activity. This allows, irrespective of donor age, growing within a short time period and without any pharmacological treatment.
- [Show abstract] [Hide abstract] ABSTRACT: The utilization of viable biological nerve graft substitutes and nerve allografts raises the problem of nerve storage. To clarify this, rat sciatic nerve segments were harvested and stored in Dulbecco's modified eagle medium. The segments were divided into three groups. In the first group, no cryoprotectant was added, whereas the second had 10% dimethyl sulfoxide (DMSO) added as cryoprotectant. These two groups of nerve segments were subjected to controlled freezing. In a third group, segments were frozen uncontrolled in liquid nitrogen (-196 degrees C). All nerves were replanted orthotopically. Fresh conventional autografts (fourth group) served as control group. Histologically, freezing did not affect the structural elements such as basal lamina tubes and perineurial tissue. Morphometrically, all cryopreserved grafts had significantly reduced axon counts and less myelinization than did controls. Cryoprotected nerves (group 2) showed no different morphometric parameters compared with the group without DMSO (group 1). Controlled freezing was superior to uncontrolled freezing (group 3). Impaired regeneration was attributed mainly to delayed Wallerian degeneration and slower revascularization. Moreover, decreased survival of resident Schwann cells in the graft may impair regeneration due to the lack of neurotrophic, neurotropic, and attachment factors in early regeneration. Grafts subjected to controlled freezing support axonal regeneration to a certain extent, but further studies are required to assess various cooling patterns, cryoprotectants, and graft revascularization.
- [Show abstract] [Hide abstract] ABSTRACT: PURPOSE: Nerve allografts are highly antigenic and, thus, require the continuous use of immunosuppressive drugs. FK 506 was found to pre-vent rejection successfully. However, clinically neurotoxic complications have been noted in the central and peripheral nervous system although an increased rate of axonal regeneration has also been shown after nerve crush experiments. To investigate whether a possible regeneration pro-moting potency of FK 506 is determined via an influence on Schwann cells, Schwann cells were cultured from the sciatic nerve of the rat. METHODS: The effect of 100 micro M FK 506 administered daily on these cultures was assessed microscopically over a period of seven days and compared to an untreated control group of cultures. Additionally, the changes in intracellular calcium were recorded using a laser scanning microscope. In vivo regeneration of autologous rat sciatic nerve grafts was assessed clinically, histologically and morphometrically after two and six weeks. The animals received a daily administration of 0.6 mg FK 506/kg body weight, the control received saline. RESULTS: In vitro FK 506 increased the Schwann cell number in culture significantly compared to non treated cultures, while the fibrocyte population was decreased. FK 506 caused a transient increase of intracellular calcium levels in cultured cells. In vivo, a significantly higher axon count was observed in the FK 506 treated grafts after two weeks regeneration compared with controls. Good regeneration was noted in all grafts after six weeks regeneration. CONCLUSIONS: The increased axon counts and decreased myelin debris in the FK 506 grafts after two weeks indicate an accelerated Wallerian degeneration and increased axon sprouting into the graft initially. The inhibition of calcineurin activity is not the mediator of the neurotrophic effect. FK 506 promotes axonal regeneration through binding to FKBP-12. The increase of intracellular calcium may induce Schwann cell pro-liferation via calmodulin. The therapeutic relevance for autologous nerve grafting, however, has to be defined in further studies.
- [Show abstract] [Hide abstract] ABSTRACT: Denatured or acellular muscle grafts are known to support axonal regeneration. With increasing gap length, failure of regeneration is evident, due to the lack of viable Schwann cells in the graft. The authors created a biologic nerve conduit, in a rat sciatic nerve model, by implanting cultured Schwann cells into an acellular gracilis muscle. Autologous nerve grafts and acellular muscle grafts without Schwann cells served as controls. After 6 weeks, regeneration was assessed clinically, histologically, and morphometrically. Polymerase chain reaction (PCR) analysis showed that the implanted Schwann cells remained viable within the graft. Good regeneration was noted in the muscle-Schwann cell group, while regeneration in the muscle grafts without Schwann cells was significantly impaired. The muscle-Schwann cell graft demonstrated systematic and organized regeneration, including the proper orientation of regenerated fibers. The number of axons regenerating through the muscle-Schwann cell grafts was significantly increased, compared with the acellular muscle without Schwann cells. Implantation of Schwann cells into acellular muscle thus provided a biologic conduit with large basal lamina tubes, as a pathway for regenerating axons. The positive effects of Schwann cells, producing neurotrophic and neurotropic factors, supported axonal regeneration.
Article: Keilhoff, G., Fansa, H., Schneider, W. & Wolf, G. In vivo predegeneration of peripheral nerves: an effective technique to obtain activated Schwann cells for nerve conduits. J. Neurosci. Methods 89, 17-24[Show abstract] [Hide abstract] ABSTRACT: In vivo predegeneration of peripheral nerves is presented as a convenient and effective method to obtain activated Schwann cells and an enhanced cell yield following in vitro cultivation. The experiments conducted in rats were aimed at clinical use in gaining Schwann cell suspensions for filling artificial conduits in order to bridge peripheral nerve gaps. The rat sciatic nerve used as a model was transected distally to the spinal ganglia. Predegeneration in vivo was allowed to take place for 1, 2, 3 and 4 days and up to 1, 2 and 3 weeks. The nerve was then resected and prepared for cell cultivation. Schwann cells cultivated from the contralateral untreated nerve served as control. Immunostaining for S100, nerve growth factor receptor and the adhesion molecules N-cadherin and L1 was used to characterize the general state of the cultures. Viability was assessed by fluorescein fluorescence staining, and the proliferation index was determined by bromodeoxyuridine-DNA incorporation. The Schwann cells from predegenerated nerves revealed an increased proliferation rate compared to the control, whereas fibroblast contamination was decreased. Best results were obtained 1 week after predegeneration.
- [Show abstract] [Hide abstract] ABSTRACT: Acellular muscle grafts can support axonal regeneration over short gaps. Due to the lack of viable Schwann cells in the grafts, failure of regeneration is evident with increasing gap lengths. To create a biological nerve conduit, Schwann cells were implanted into acellular muscle. The grafts were then incubated in vitro and assessed histologically and morphometrically. For cultivation of the Schwann cells, rat sciatic nerves were allowed to predegenerate to obtain a high cell yield. Rat gracilis muscles were harvested and made acellular by a liquid nitrogen treatment. After Schwann cell implantation, the muscles were incubated in vitro for 2, 5, and 7 days. S100-immunostaining, NGF, and N-cadherin, characterized the Schwann cells within the muscle. Viability was assessed by fluoresceine-fluorescence staining. Proliferation was determined by BrdU-DNA incorporation. Cell implantation did not to affect Schwann cell viability. Cells were seen throughout the entire length of the muscle basal lamina. They aligned and formed a cell column. Immunostained for S-100, implanted cells showed 100 percent staining. N-cadherin and NGF were expressed by all of the S-100 positive cells. Predegeneration is considered to be a highly efficacious method, if a high yield of activated Schwann cells is required. The successful implantation of the cells into an acellular muscle provides the possibility of a biologic conduit, offering the advantage of large basal lamina tubes serving as a pathway for regenerating axons. It also provides the beneficial effects of viable Schwann cells that produce neurotrophic and neurotropic factors to support axonal regeneration. Functional outcomes require evaluation in further in vivo studies.
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Otto-von-Guericke-Universität Magdeburg
Magdeburg, Saxony-Anhalt, Germany
- Clinic for Plastic Surgery, Aesthetic and Hand Surgery


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A legislative panel reviewing state-run attractions now says it will not recommend that an Elizabeth City museum close.
A subcommittee of the Legislature's fiscal management panel also decided Wednesday against recommending that a shrine to North Carolina's first governor close.
Committee staff members had recommended closing of the Museum of the Albemarle and the Richard Caswell Memorial in Kinston.
Both attractions have below-average attendance compared to other state museums and historic sites. But local boosters have opposed closing them, saying it would discourage tourism and economic development in eastern North Carolina and close an eye to state history.
The subcommittee's recommendations now go to the full panel, which will provide guidance to the General Assembly when it makes budget decisions in a few months.

subset: commoncrawl


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Also opening:Bernardo Bertolucci's "Me and You" (Emerging), his first feature in a decade and only his third Italian language film since 1970 opened in two prime New York theaters two years after its Cannes premiere, but no grosses are available.
Last week's openers:
"Begin Again" (Weinstein) - $1,316,000 in 175 theaters (+170); PSA: $7,520; Cumulative: $1,853,000
Taking a significant risk (and adding marketing expense) with this wider-than-usual second week release, Weinstein seems to have succeeded in justifying the benefit-of-the-doubt reaction to their decent if not spectacular initial New York/Los Angeles grosses (which ended up coming in 10-percent less than they estimated). The PSA for this level of theaters puts the film on track for at least a $15-20 million domestic gross, with the potential for much more if word-of-mouth continues to overcome mixed reviews.
TWC's "Quartet," for example, went to 163 theaters on its third weekend with a PSA of $7,110 before getting to $18 million. "Chef," which is heading to $25 million or more, played far fewer theaters its second weekend (with a resulting better PSA) and averaged $8,843. This is ahead of "Enough Said," "The Way, Way Back" and "Belle" at comparable stages. This opened in most of these theaters on Wednesday. Friday showed by far the biggest percentage jump from Thursday of any film in the market and Saturday had a decent improvement on that figure.
This film is in Weinstein's wheelhouse. That doesn't mean it's a guaranteed success. But the high-end marketing/advertising support, the timing (lighter-weight, more general audience appeal film with some sophistication) at a time with little else for adults in the market (particularly older female) and most importantly strong word of mouth are all combining to make this look even more like a strong crossover success than it initially appeared.
This will get to around 800 or so screens (a very quick expansion) this Friday.
"Snowpiercer" (Radius/Weinstein) - $998,325 in 250 theaters (+242); PSA: $3,993; Cumulative: $1,501,844
Last week was no fluke. This quick expansion of Bong Joon-ho's ice-age-survivors-on-a-train story resulted in a very impressive number once again. The numbers are below "Begin Again," but it's astounding considering the normal level of performance of the theaters playing it. The film's Video on Demand availability on July 11 means most of the usual theaters that play top specialized films aren't present -- including the Landmark chain. Within that context, these numbers suggest that had this gone a normal theatrical pattern (with an expedited and well-supported marketing campaign) the potential was there for a $20 million-plus crossover appeal film.
Last summer, Weinstein, after authorizing a reedited cut for US theaters, opened Wong Kar-wai's "The Grandmaster" and went as wide as 800 theaters with a $6.5 million gross. That's impressive for a subtitled film. "Snowpiercer," which Weinstein finally didn't cut, is in English, with a combination of great reviews and some action/genre appeal (both ahead of "Grandmaster") yet seems to have been relegated, at least theatrically, to a second-tier treatment.
The strong opening suggests significant interest, particularly from younger (less typical) specialized moviegoers, exactly the kind of viewers who gravitate to streaming services. And, though it might not have been the intent, the pattern here -- top-drawer film gets attention, even without great theaters, then quickly goes to VOD (which is not the established method -- usually films either go VOD at the same time, or perhaps after one week; third week or soon after is quite unusual) -- could if successful end up being used for other films. That would be risky -- as the playoff here shows, it cut outs many of the best specialized theaters. But this might turn out overall to become one of the most telling releases of the year.


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Barrow Lamb
previously known as Lamb & Flag
Stoney Ln
grid reference TL 772 640
Something we've got wrong about this establishment? Something more you think we should know about it? Please email us
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last updated 21/02/2016
listed building grade II
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CAMRA West Suffolk & Borders branch.
last updated 21/02/2016
Now split into two homes; Old Lamb House and Lamb Cottage.
The building dates from the early 19th century.
(Most pub, location & historic details collated by Nigel, Tony or Keith - original sources are credited)


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Relay on the River set to light up the night
"In the right light, at the right time, everything is extraordinary," Aaron Rose once said.
On Aug. 27, Relay for Life organizers are hoping that the right light produced by hundreds of luminarias will make a local effort to fight cancer extraordinary.
Individuals throughout Tunica County are now selling luminarias that will honor cancer survivors, support those currently battling the disease and remember those who have lost the battle. In addition to serving as a tribute, the small bags, filled with sand and a candle, will be used to light up Rivergate Park when the sun sets.
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River Rd. repair to begin in June "B-lump...b-lump...b-lump."...
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Cut in funding threatens Adolescent Opportunity Program statewide Local Adolescent...
Aerospace entrepreneurs envision 'Silicon Valley of the South' in MS Tunica is slated...
Town greenlights remote read meters Town of Tunica aldermen...
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In this particular live game against a 1600, I could say I have reached a descent level of tactical play. I guess because down on time, my opponent failed to calculate correctly the tactical move that I threw on move 18...Nxe4 and this resulted to a sequence of piece exchanges that favored my side. By move 25, I had to and played sharp and forcing moves, which resulted in a fairly nice mating pattern.
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My Taurus will start and run (rough) with water billowing out the tailpipe. Head Gasket problem. A friend mentioned there is a product I could use like a sealant to fix the problem and maybe get another year or two out of the car. What might this product be and what would it entail? No water in oil.
by beast4th in Vancouver, WA on February 06, 2011


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Related Articles
- India to seek expeditious sharing of bank info from Swiss govt: Arun JaitleyUK firm East India Company honours Sachin Tendulkar with rare gold coinCisco sets up dedicated $40 mn India fund for early-stage companiesBlackBerry Z3: 4 reasons why this affordable phone might be a good buy
Switzerland is on course to share tax-related information with India by August 1 this year. The Swiss government on Monday put up the revised Tax Administrative Assistance Act on its website with the critical assurance that in no Swiss canton (state) has a referendum been called against the bill.
This means the Indian government will now find it easier to access information on Indian account holders in Swiss banks. Earlier on Monday, finance minister Arun Jaitley said in response to a news report that the Swiss were preparing such as list his ministry planned to approach the Swiss government for a list of such account holders.
The referendum deadline will expire on 10 July 2014, and no referendum has been called to date. If that remains the case, the amended act will enter into force on 1 August 2014, the website of the State Secretariat for International Finance Matters (SIF) said.
The Act will make it possible for the Swiss government to override several provisions of secrecy rules that banks in that country deploy to keep the ownership of their account holders a secret from prying countries. The last date for cantons to give a notice for referendum is July 10 but since it requires signatures of at least 50,000 people in a 100-day period, the chances of the Act not going through now are remote.
The country has been under tremendous pressure from the international community to share information on these bank accounts, many of which are often allegedly used by people and institutions to evade taxes in their respective countries.
New Delhi has repeatedly asked the Swiss government to share information on such bank accounts allegedly held by Indian nationals in banks in that country without paying taxes on them. But Bern has pleaded that while it is keen to help India, it cannot transgress its domestic laws to share such information. India, for instance, has asked for information it received on an alleged set of HSBC accounts obtained from third-party sources, but the Swiss government has maintained it cannot act on stolen data. This act will allow Zurich to bypass this restriction.
The Swiss Tax Administrative Assistance Act cleared by its Parliament proposes to amend domestic laws in line with international standards for tax transparency. Through passage of this act Switzerland will comply with the applicable international standard for administrative assistance in tax matters as well as


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The Five-Year plan
Thursday, July 24, 2008
Wow, I haven't done a five-year plan since high school :) This is a good exercise to do every now and then, for many reasons. I distinctly remember when I first started practicing law, I ignored almost everything except for work. One day I looked in the mirror and realized 5 years had gone by. I had gained more than 50 pounds and hated my job. I felt like a bunch of time had been wasted. NEVER AGAIN!!
In the next five years, I will turn 40. Seems hard to believe, but it is true. I always thought that I might go back to school at some point, because I really do enjoy it. It is not about getting another degree; I certainly don't need that piece of paper. But I do enjoy the discourse and exercising my brain. I'm not sure that school is really in my five-year plan, but I do want to remember that it is out there on the horizon.
With that out there, my goal over the next five years is to find a job that is both intellectually satisfying, but also not all-consuming. As I have been doing for the last three years, I am struggling to find the balance between being a wife, a mother, and a professional. As part of this plan, I want to put as much money as reasonably possible towards retirement, so that I can comfortably go back to school when the time is right.
Steps to take for this plan:
1. By the end of 2008, read "Things you can do with a Law Degree" and take a few self-assessment tests. I have been saying I was going to this for years, and now I just need to do it!
2. Start putting at least $500 a month away for retirement NOW.
3. Send out resumes.
4. Go to bar association lunches. Go to my first one by October 1, 2008.
One more thing in my five-year plan -- another baby. I'm not 100% sure that we want another one, but this must be decided within the next five years (We're not getting any younger!)
The steps for this plan are pretty simple:
1. Decide if we want another baby (duh). Have this discussion with dh by January of 2009.
2. GET TO GOAL WEIGHT -- by February 2009.
3. Set out a plan for the best time to get pregnant is within the next five years.
4. Get pregnant
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Jenn I love your five year plan!!!!! If nothing else it makes you think about real possibilities. I absolutely know what you mean by going back to school.......I love that and plan to do that myself. I agree, it is not so much the pieces of paper as the intellectual discussion etc.
One thing you might want to consider just for the fun of it is Babyfit.com which is a sister site of Spark. In the event that a pregnancy is in your future a great place to be while trying to conceive, during pregnancy and directly afterwards is that site. I have met many women who have come into this site after being over at Babyfit. Great site, free and full of info. Lots of professional women trying to juggle everything in there and plenty of exchanges regarding that particular subject.
I think you would have fun networking at the Bar and the functions.......matter of fact between that and maybe the Chamber you just might come up with new and different ways to use your education and experience!!!!!!!
I know whatever your decisions and however you decide to implement them you have a wonderful future ahead!!!!!!!!!!!!!!!!!!!!
2849 days ago
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Wow!1 You've clearly got that analytical mind thing goin'!!
Sounds like a sound plan. S.M.A.R.T. and all of that.
2867 days ago
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KPMG has been recognised for forward-thinking leadership and exceptional commitment to client support.
What start-ups need to consider? Where to get access to information? What events they can consider to attend?
The Global Financial Crisis (GFC) has had a major impact on all parts of the global economy and has called into question some of the fundamentals of our economic system. We are still learning the lessons from a financial crisis that has raised so many questions. A key focus area has, and will continue to be, the quality of Business Reporting (BR), the role it plays in restoring trust in the markets and how it will evolve as a result of lessons learnt.
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The KPMG name and logo are registered trademarks or trademarks of KPMG International.
KPMG International Cooperative ("KPMG International") is a Swiss entity. Member firms of the KPMG network of independent firms are affiliated with KPMG International. KPMG International provides no client services. No member firm has any authority to obligate or bind KPMG International or any other member firm vis-à-vis third parties, nor does KPMG International have any such authority to obligate or bind any member firm.


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Who Is This Man? And Where Does He Work?

Having seen an advance screener of the Top Chef premiere, we're all set and ready to dig in and immerse ourselves in the show's patented straight-faced lunacy this season. But something is getting in the way. The most annoying of the new cheftestants — this season's Howie — is the high-strung Andrew, supposedly a cook somewhere here in New York. But where? His Top Chef bio calls him a "Sous Chef in NYC," but no one seems to be able to give us a hint of where. (One tipster seemed to think that it was at Tocqueville, but the lead was a dead end: Jo Ann Makovitzky, Tocqueville's co-owner, tells us, "He does not look familiar to me.") Have you seen this man? Tell us all about him in the comments. Top Chef Cheftestant Bio: Andrew [Bravo] Related: What to Expect From the New 'Top Chef' Update: The mystery has been solved. An Eater reader has IDed Andrew D'Ambrosi as a sous chef at Le Cirque.
Top Chef Cheftestant Bio: Andrew [Bravo]
Related: What to Expect From the New 'Top Chef'
Update: The mystery has been solved. An Eater reader has IDed Andrew D'Ambrosi as a sous chef at Le Cirque.


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May 31, 2016
A box review by defeated Winston County Sheriff's candidate Ronnie Flake was completed Wednesday.
The final total in the close sheriff's race including affidavit ballots:
Walter Coburn (D) 4094
Ronnie Flake (I) 4070
Flake lost to democrat Walter Coburn, according to certified results from the Nov. 4 election.
Coburn has also now asked to review the boxes. That process will begin Monday.
In addition, Circuit Clerk Glenda Johnson said she received a request for a box review in the district 3 supervisor's race.
Republican Tom Blalock was the winner by a 972 to 911 margin over democrat Joe Louis Jernigan. That process also begins Nov. 24.
Click Here to access the online Public Inspection File
Viewers with disabilities can get assistance accessing this station's FCC Public Inspection File by contacting the station with the information listed below. Questions or concerns relating to the accessibility of the FCC's online public file system should be directed to the FCC at 888-225-5322, 888-835-5322 (TTY), or firstname.lastname@example.com.


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"Can you at least tell me where you want me to take you?" you asked Loki pleadingly.
"No," he replied, smiling at you.
You drummed your fingers on the kitchen table as Loki gobbled up the pasta dish you made for lunch. You weren't as hungry as you thought you were.
"You know, this arrangement hardly seems fair," you said.
"To what arrangement are you referring?" Loki asked.
"The one where you know so much about me and I know next to nothing about you."
"Well, what do you want to know, [name]?"
"Why you're here. Why you're hell-bent on taking over the world. Like I've said twenty times."
"And, as I've said numerous times, I won't tell you just yet."
You made some sort of sound between a groan and the call of a howler monkey. Loki chuckled.
"You'll warm up to me soon enough," he said.
He was about to pat you on the shoulder, but you backed up.
"Right. My apologies, dear."
"And I told you to stop calling me that!"
"It's not very likely that I will, [name]."
Night fell, and in your agitation, your foot tapped wildly against your living room floor. Loki walked into the room, back in his clothing from when he arrived.
"Come," he said softly, gesturing to you.
You stood up and got your keys. You opened the garage door and barked at Loki to get in. Soon, you were off, headed to who-knows-where. Loki gave you turn-by-turn directions for where he wanted to go. After a while, you were traveling down a long, straight road.
"I appreciate your compliance with my wishes, [name]," Loki said, almost kindly.
"You threatened to kill me if I didn't! Resistance isn't exactly an option for me!" you retorted.
"You humans are fascinating. I threaten your life, and you know for a fact that I would kill you, yet you would still sleep while I am in the same house."
"It was four in the morning!"
"Nevertheless, I believe you are beginning to enjoy my company."
"Wow, Loki. Way out of line. I don't like you, I barely tolerate you."
"You're so bad at lying, [name]. I would know. The truth is written all over your face."
He looked up as you swallowed hard.
"Pull over here."
You pulled over into the dirt on the side of the road. Loki got out of the car and walked around to your window.
"I'll be gone shortly," he said. "You needn't wait here for me."
"Wasn't planning on it," you replied flatly.
Loki swiftly took your hand. You saw, very clearly in your mind's eye, a vision of yourself walking down the street last night, when you had seen Loki for the first time. Loki planted a gentle kiss on the back of your hand before walking out toward the flat landscape. The emotional transference was strange this time. You felt something
sweet. You weren't quite sure what it was. You watched Loki walk a ways out, then disappear into a rainbow-colored beam. You blinked in disbelief before turning the engine back on and hauling ass back home.
Loki X Reader-Chapter Four by ReaperRoseWatch
©2012-2016 ReaperRose
I swear, there will be more background in the next chapter. I'm writing it right now. If you're wondering where Loki went, he used the Bifrost to go to Asgard, then catch an immediate connection to New Mexico, where Thor just got taken in for beating the crap out of the SHIELD people to get to Mjolnir ^^
I needed Loki to be stubborn for this one, but he opens up soon. "It is madness, yet there's method in't." -Shakespeare
I needed Loki to be stubborn for this one, but he opens up soon. "It is madness, yet there's method in't." -Shakespeare
This story is suspenseful! YOu didn't make your other story like this. ARGS! Uncool, still a fun story. I'm still reading it. Can't wait to read the next chapter. :-D
Bloody jerk.
Genius..Just..Genius XD
............ um you can't just give that kind of emotional transfer and then just leave you a**!
so I Left him?...............AHAHAHAHAHA THATS SO ME xD
Awesome story so far! I can't wait to read the rest!
For some reason I thought of him saying "I have to pee" when I pulled the car over and after I left he was like "O.O WHHHHHHHHYYYYYYYYYYYY???" and then it started raining XD
*rolls around on floor* I should be studying right now, but this is so much better than Music History....
well that turned out rather well. I thought for a moment he was just going to do away with us and have done!
But then again, that really wouldn't fit into his plans would it?
But then again, that really wouldn't fit into his plans would it?
Guh. Kissing the hand.
-is eagerly awaiting the next chapter already- Damn this is getting intense O_O


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It's Decent
2000 BMW 3 Series
Crutchfield Customer Review (What's this?)
I purchases this for my son and was not that happy with it. The sound, while clear, is not as powerful as I had hoped. I feel like it lacks hit that a subwoofer should have and served more as an expensive amplifier than a subwoofer. After having it for 5 months, we are in the process of selling it and upgrading to a more powerful and effective sub.
Pros: Small, good sound quality
Cons: Not very powerful


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Heyy, I am new to this forum. I would just introduce myself here. I am Ash from Toronto, Canada. I am pretty athletic and love to ride bikes even though i havent had one for like a year now. I am 14 years old, 5'8" and 120 something lbs.
Now, the reason I joined. I found a Peugeot 103 bike. Okay, I love to ride bikes but thats about it. I dont know anything about bikes. I just thought the bike was cool with thin racing tires and stuff so I just bought it along with me.
It is quite rusted but I have checked the brakes and stuff and they are fine. The tires are flat but I dont think theres any leak so no big deal I guess. The brakes are Weinmann and the Derailleur is Simplex. The epdal crank says Custom A and the tire is Tai Yung. And it says Sport on the top tube.
It is in decent condition, there is rus but nto a lot, I could deal with that. But the derailleur is jammed. I tried moving the paddles but they get stuck. I just want to use it for recreational purposes, not really any racing or long distance travelling. So here are my questions-
1. Is it too big for me? I want to keep it.
2. What can I do to fix the derailleur?
3. Is this bike too old?
4. Anything else I should check for or get fixed in the bike?
Thanks a lot guys, I would really appreciate anything you can tell me


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Are you an event planner, or has someone "volunteered" you to organize that ski lodge reservation for all of your friends? Don't fear--Wufoo is here. We've created a pretty fabulous collection of online registration forms and registration form templates to make organizing events a painless process.
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Posts from Sales & Events
Weekend Guide: Sales & Events Calendar
November 22, 2013
Shopping season is officially here and retailers are ramping up savings as we near the pinacle of the shopping calendar, Black Friday (stay tuned for our super-huge Black Friday shopping list next week). Traveling somewhere exotic this holiday? Get a LUXE city guide at half price. Get a jump on big ticket gifts with 15% off all Herman Miller at All Modern or prepare for holiday out-of-towners at The Futon Store's pre-Black Friday sale. All that and more after the jump.
Home Tech & Appliance Deals: Holiday Entertaining Edition
Tech Deals of the Week
Whether you're looking to set the perfect holiday mood with music and lighting, looking to enjoy the Macy's Thanksgiving Parade on a big screen, help overnight holiday guests stay connected and charged, or even setting out to plan a post holiday meal exercise program, we've gathered some of the best sales deals for before, during, and after the day we give thanks...
Weekend Guide: Sales & Events Calendar
November 14, 2013
Lots of deals this week for every room in your home. Save on bedroom essentials at Au Lit, Pottery Barn and DWR, kitchen and bath at Greentea Designs, lighting at Lightology or snap up some cute, colorful carpet tiles on sale at FLOR. All that and more when you read more.
Deals & Discounts: Best Buys for Pet Lovers
Tech Deals of the Week
For many of us, our felines and canines are what make our house a home. So this week's sales calendar focuses on an assortment of pet accessories, furnishings, and home cleaning options all revolving around keeping our pets happy at home, including discounts on automatic pet feeders, laser light games, self-cleaning litter boxes, backyard training/monitoring devices, and much more...
Weekend Guide: Sales & Events Calendar
November 8, 2013
We're inching closer and closer to the holidays so get your home in order with sales on sleep solutions at DWR and Au Lit, as well as cozy decor for your floor (at Flor, naturally). See our NYC finds for National Toy Store Day (it's tomorrow) or attend a humanitarian design workshop aptly named, "Design Like You Give a Damn." All that and more after the jump.
Boost Your Productivity With A Faster Smartphone, Tablet, Laptop, PC, Or Mac
Tech Deals of the Week
It might finally be time to ditch that dinosaur of a PC and upgrade to the latest and greatest. Upgrade the home office with tech to keep you productive and getting things done without having to wait for that darn hourglass to churn. There's much more than just a typical new desktop computer, with new convertibles that transition between laptop and tablet, touchscreens, and even hands free options. Find discounted Apple setups, tablets, smartphones, and more in this week's sales.
Weekend Guide: Sales & Events Calendar
November 1, 2013
Believe it! It's already November so get your house ready for those holiday guests with 20% off bedding at Au Lit, or stock up on discounted wine and dine supplies at Crate & Barrel. In San Francisco this weekend, check out the International Vintage Poster Fair, featuring vintage vendors from around the globe. All that and more when you read more.
Get Organized: Deals & Sales to Help Get Your Whole House in Order
Tech Deals of the Week
As the fall and winter holidays near, now is a good time to get your house in order for guests. This week's sales roundup can help in the home organization and storage department, whether it's your living room, home office, or even your laundry room...anything and everything to hide cables, cords, remotes, and anything else you'd rather keep out of sight!
Weekend Guide: Sales & Events Calendar
October 25, 2013
Plenty of great deals this week on everything from modern furniture at Blu Dot to Ylighting and carpet tiles from Flor. If you're more of a fan of the independent artisan, don't miss the Brooklyn maker's market, Factory Floor, or the Contemporary Craft Market in Los Angeles. All that and more after the jump.
One Room, On Sale: Kitchen Appliances & Accessories
With the arrival of autumn, many of us are now focusing on entertaining at home for the holidays, which means more time in the kitchen. Appliance sales are aplenty, including a big IKEA kitchen sale and numerous discounts on almost every cooking and kitchen prep device, all listed below...


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Varla Jean Merman in The Divine Sister: Charles Busch's Send-up of Nuns in Hollywood
* Additional fees apply. No coupon or promo codes necessary to enjoy the displayed discount price.
The last date listed for The Divine Sister was Saturday November 19, 2011 / 8:00pm.
Currently at Calderwood Pavilion at the Boston Center for the Arts
Romantic Musical Inspired by River Phoenix Film: Dogfight
- Full Price:
- $45.00 - $65.00
- Our Price:
- $22.50 - $32.50
Based on the 1991 film starring River Phoenix and Lili Taylor, Dogfight takes place in 1963, with… More
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Reviews & Ratings
Featured review from Goldstar Member
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The cast was great! Off to a slow start, but soon some very funny spoofing. Would make a good Harvard hasty pudding show. Lots of good one-liners.
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Everyone was fabulous!
star this review starred report as inappropriate
Totally over the top, campy, and fun with moments of unintentional hilarity (when props didn't appear where they were supposed to) adding to the fun.
A great time overall, tho a couple of the actors came across as not very good, not campy --...continued
star this review starred report as inappropriate
Lots of laughs in this rather risque show. Not suited for those who are shocked by off-color language. Many laughs and great acting.
Varla Jean Merman, Paula Plum and Kathy St. George star in The Divine Sister, an inspired homage to nearly every Hollywood film ever made about nuns. Written by Charles Busch, the comic genius behind such classics as Die, Mommie, Die!; Psycho Beach Party, and Vampire Lesbians of Sodom, this gleefully twisted tale tells the story of an indomitable Mother Superior trying to cope with a young postulant experiencing visions, a sensitive schoolboy in need of mentoring, a mysterious nun visiting from Berlin, and a former suitor intent on luring her away from her vows.
About the Ticket Supplier: SpeakEasy Stage
Over the past nineteen seasons, SpeakEasy Stage Company has distinguished itself as Boston's premier theater staging Boston premieres. Year after year, SpeakEasy has won acclaim for presenting top-quality productions of vital, cutting-edge plays.
Recently, SpeakEasy was singled out by Variety, the entertainment newspaper, as a force in regional theater and a champion of small, often overlooked musicals.


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For pattern creation in UV-curable materials from a prestructured stamp to
a substrate.
The EVG620 allows for imprint processes with stamps to substrates ranging
from small chip size pieces up to 150 mm in diameter. Configurations for
nanotechnology applications can include release mechanisms for stamps in
addition to programmable high and low contact force. Uniform contact force
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Customers Have Voted EV Group as one of the World's Best Suppliers in the VLSIresearch 2016 Customer Satisfaction Survey
EV Group Receives Multiple Orders for GEMINI® FB XT Fusion Bonder for 3D Chip Stacking Production Applications
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Historical Narrative
USS Ponchatoula, the sixth tanker in the Neosho-class
of fleet oilers, was laid down in Camden, New Jersey, by the New York
Shipbuilding Corp. on March 1, 1954. The ship was launched on July 9,
1954 and it was commissioned on January 12, 1956.
Although Ponchatoula
was a support vessel rather than a combat ship, it came equipped with
two five-inch guns and 12 rapid-fire three-inch anti-aircraft guns
mounted in several gun tubs.
Ponchatoula had a very long and
distinguished career. In addition to serving the majority of its career
in Southeast Asia, from 1963 through 1967, it assisted in a number of
historic recovery operations for the Projects Mercury and Gemini
spaceflights. During the spring of 1966, Ponchatoula set a Navy record by refueling hundreds of vessels.
Although Ponchatoula
continued to serve successfully in the Western Pacific, newer and more
modern fleet oilers were being added to the Navy's Pacific Fleet. After
43 years of service, Ponchatoula was removed from the Navy's
active duty fleet on August 31, 1992, after having been berthed at the Suisun Bay Reserve Fleet that April..
On May 1, 1999, the Navy
transferred ownership the ship to the Maritime Administration. It remains at Suisun Bay.
Naval History and Heritage Command Dictionary of American Naval Fighting Ships entry on USS Ponchatoula.
No documents for this vessel
Date: 4/2/1992
Vessel entered Suisun Bay Reserve Fleet
Date: 5/1/1999
US Navy transferred title to MARAD
Cleared Historic Review
Date: 6/21/2005
California SHPO cleared the ship for disposal on this date.
Ship Imagery
Status Cards
No documents for this vessel


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Key things you need to know aboutDr. Eggleston III:
Dr. Eggleston III's Experience
Research training, expertise and qualifications
Dr. Eggleston III's Specialties
- Breast Reconstruction Surgery
- View all 4 Specialties and 2 board certifications
Procedures Dr. Eggleston III Performs
- Abdominoplasty
- Arm Surgery
- See all 27 procedures
Conditions Dr. Eggleston III Treats
- Breast Cancer
- Breast Diseases
- See all 5 conditions
More About Dr. Eggleston III's Background
Hospital Quality
The right hospital is as important as the right doctor
- St. David's Medical Center
- 919 E 32nd St
- Austin, TX 78705
- St. David's Georgetown Hospital
- 2000 Scenic Dr
- Georgetown, TX 78626
9 Facts About Hospital Quality
Patients' risk of dying during a hospital stay for heart bypass surgery could be 87.4% lower, on average, at a hospital rated 5 stars compared to a hospital rated 1 star for that procedure. Choosing the right hospital is critical to your health. View Slideshow
Patient Satisfaction
Patients' feedback on their experience with Dr. Eggleston III
Likelihood of recommending Dr. Eggleston III to family and friends is 5 out of 5 5 1 4
See More Survey Results
8 Facts About Patient Satisfaction Surveys
Patient satisfaction surveys provide a standardized way of reporting about healthcare experiences. But there can be more than meets the eye when reviewing scores. Here's what you should know
Appointments & Offices
Check insurance plans, locations and make an appointment
Accepting new patients?
- Yes
- Plastic Surgery Associates
- Breast Reconstruction Associates
- 1015 E 32nd St Ste 306
- Austin, TX 78705
- (512) 815-0123
- Directions
7 Tips to Prepare for Your Appointment
The key to a successful appointment is communication. To get the most out of your visit, prepare ahead of time so you can lead the conversation with your doctor. These 7 tips will get you ready
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4G Americas Publishes a Detailed Report on the Developments in 3GPP Release 11 and 12 Standards
BELLEVUE, Wash. (Feb. 12, 2014) – 4G Americas, a wireless industry trade association representing 3GPP mobile broadband technologies, today published a detailed report on the 3GPP standards in Release 11 (Rel-11) and the work nearing completion in Release 12 (Rel-12). The white paper, titled, 4G Mobile Broadband Evolution: 3GPP Release 11 & Release 12 and Beyond, provides an in-depth look into 3GPP technology standards, including HSPA+, LTE-Advanced and Machine Type Communications (MTC).
"Innovations in 3GPP network architecture have been carefully planned to maximize capacity, efficiency and the user experience at the dawn of the age of the Internet of Things," commented Vicki Livingston, Head of Communications for 4G Americas and co-leader of the 4G Americas working group that produced the white paper. "The global success of HSPA+ mobile broadband and the current explosion of LTE connections can be attributed to the future planning in 3GPP standards work that has set forth the clear roadmap to LTE-Advanced and beyond."
LTE-Advanced, based on 3GPP Release 10, has been commercially deployed by five mobile network operators worldwide: SK Telecom, LG U+ and KT Telecom in South Korea, EE in the U.K. and Saudi Telecom Company in Saudi Arabia. It is expected that the four national service providers in the U.S.—AT&T, T-Mobile USA, Sprint and Verizon— will all deploy LTE-Advanced in 2014. The standards work developed at 3GPP is evolving today's mobile broadband technologies by aiming to address the immense challenge facing mobile network operators in the coming years as the 1000x mobile data challenge draws near.
3GPP Rel-11 standards for HSPA+ and LTE-Advanced were frozen in December 2012 with the core network protocols stable in December 2012 and Radio Access Network (RAN) protocols stable in March 2013. Key features detailed in the paper for Rel-11 include:
- 8-carrier downlink operation (HSDPA)
- Downlink (DL) 4-branch Multiple Input Multiple Output (MIMO) antennas
- DL Multi-Flow Transmission
- Uplink (UL) dual antenna beamforming (both closed and open loop transmit diversity)
- UL MIMO with 64 Quadrature Amplitude Modulation (64-QAM)
- Several CELL_FACH (Forward Access Channel) state enhancements (for smartphone type traffic) and non-contiguous HSDPA Carrier Aggregation (CA)
- Carrier Aggregation (CA)
- Multimedia Broadcast Multicast Services (MBMS) and Self Organizing Networks (SON)
- Introduction to the Coordinated Multi-Point (CoMP) feature for enabling coordinated scheduling and/or beamforming
- Enhanced Physical Control Channel (EPDCCH)
- Further enhanced Inter-Cell Interference Coordination (FeICIC) for devices with interference cancellation
Finally, Rel-11 introduces several network and service related enhancements (most of which apply to both HSPA and LTE):
- Machine Type Communications (MTC)
- IP Multimedia Systems (IMS)
- Wi-Fi integration
- Home NodeB (HNB) and Home e-NodeB (HeNB)
3GPP started work on Rel-12 in December 2012 and an 18-month timeframe for completion was planned. The work continues into 2014 and areas that are still incomplete are carefully noted in the report. Work will be ratified by June 2014 with the exception of RAN protocols which will be finalized by September 2014. Key features detailed in the paper for Rel-12 include:
- Universal Mobile Telecommunication System (UMTS) Heterogeneous Networks (HetNet)
- Scalable UMTS Frequency Division Duplex (FDD) bandwidth
- Enhanced Uplink (EUL) enhancements
- Emergency warning for Universal Terrestrial Radio Access Network (UTRAN)
- HNB mobility
- HNB positioning for Universal Terrestrial Radio Access (UTRA)
- Machine Type Communications (MTC)
- Dedicated Channel (DCH) enhancements
- Active Antenna Systems (AAS)
- Downlink enhancements for MIMO antenna systems
- Small cell and femtocell enhancements
- Machine Type Communication (MTC)
- Proximity Service (ProSe)
- User Equipment (UE)
- Self-Optimizing Networks (SON)
- Heterogeneous Network (HetNet) mobility
- Multimedia Broadcast/Multicast Services (MBMS)
- Local Internet Protocol Access/Selected Internet Protocol Traffic Offload (LIPA/SIPTO)
- Enhanced International Mobile Telecommunications Advanced (eIMTA) and Frequency Division Duplex-Time Division Duplex Carrier Aggregation (FDD-TDD CA)
Work in Rel-12 also included features for network and services enhancements for MTC, public safety and Wi-Fi integration, system capacity and stability, Web Real-Time Communication (WebRTC), further network energy savings, multimedia and Policy and Charging Control (PCC) framework.
All the mentioned enhancements in the standards work are carefully explained in the white paper, outlining the clear road forward in the development of 3GPP mobile broadband standards. The importance of this planning cannot be minimalized in the face of a global interconnection of billions of things today, and an increasing number of devices in the future of the Internet of Things.
"Mobile communications have become such an essential part of our lives that we sometimes take its presence for granted, like air or sunshine," stated Michael Peeters, CTO, Wireless Business Line at Alcatel-Lucent and leader of the 4G Americas working group. "We see it as a key driver to continued human and economic development; with it, access to everything from health information and banking to news and social media stimulates job creation and citizen participation."
4G Mobile Broadband Evolution: 3GPP Release 11 & Release 12 and Beyond, was written collaboratively by members of 4G Americas and is available for free download at: www.4gamericas.org.
About 4G Americas: Unifying the Americas through Mobile Broadband Technology
4G Americas is an industry trade organization composed of leading telecommunications service providers and manufacturers. The organization's mission is to advocate for and foster the advancement and full capabilities of the 3GPP family of mobile broadband technologies, including LTE-Advanced, throughout the ecosystem's networks, services, applications and wirelessly connected devices in the Americas. 4G Americas contributes to the success of 3GPP technologies and their No. 1 place in the region. 4G Americas is headquartered in Bellevue, Wash. More information is available at www.4gamericas.org.
4G Americas' Board of Governors members include: Alcatel-Lucent, América Móvil, AT&T, Cable & Wireless, Cisco, CommScope, Entel, Ericsson, HP, Mavenir, Nokia Solutions and Networks, Openwave Mobility, Qualcomm, Rogers, T-Mobile USA and Telefónica.
Vicki Livingston
4G Americas
+1 262 242 3458
+1 262 242 3458


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Mazda recalled certain models due a problem that could cause the fog light bulb to fall out of the fog light assembly. The repair involved inspecting the fog lights and installing a spring clip to prevent the light bulb from falling out.
RepairPal Verified
Average mileage: (–)
1 model year affected: 2003
1 person reported this problem


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STARmeterSEE RANK
Up 205 this week
Carly Craig (I)
Born and raised in San Diego, California, Carly comes from a large Italian-Irish family that includes two professional baseball players: her father, Rocky Craig, and little brother, Casey Craig. She has one sister and two brothers. Carly is well-known on the internet for her hilarious and disturbingly-edgy songs and improv pieces, most notably "The... See full bio »
More at IMDbPro » Contact Info: View agent, manager, publicist and legal


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The noise seems to be from the rear fan (3rd seat area). It even clicks when the car is not in motion (not running/no key). At first I thought it was only when I was trying to cool the back of the vehicle but now that the weather is cold, the noise comes and go even when trying to heat.
by Swager7 in Ankeny, IA on November 27, 2012


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NCI Dictionary of Cancer Terms
The NCI Dictionary of Cancer Terms features 7,899 terms related to cancer and medicine.
Browse the dictionary by selecting a letter of the alphabet or by entering a cancer-related word or phrase in the search box.
- contrast esophagram
- listen (KON-trast ee-SAH-fuh-gram)
A series of x-ray pictures of the esophagus taken after a patient drinks a liquid containing barium sulfate (a form of the silver-white metallic element barium). The barium sulfate coats and outlines the inner wall of the esophagus so that it can be seen on the x-ray pictures. Also called esophagram.


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Nebula Computer Software in Business / Project Management
NBL Purchasing is a Windows database-driven software designed for soho, small and medium size company, to manage and monitor purchasing process, from receive quotation, issue purchase order, receive material to validate supplier bill. Include feature: Master Editor: Store Supplier, Employee, Organization particular / contact and Material information Issuing: Print, fax Purchase Order or export to pdf file Listing: Query, print or export master data and purchasing data to file for viewing Security: Control user to access the data with user management.
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Tapaculos (Rhinocryptidae)
Vilcabamba Tapaculo (Scytalopus urubambae) - HBW 8, p. 780
French: Mérulaxe de Vilcabamba
German: Vilcabambatapaculo
Spanish: Churrín de Vilcabamba
Taxonomy: Scytalopus magellanicus urubambae J. T. Zimmer, 1939, Cedrobamba, 12,000 feet [c. 3660m], Urubamba Valley, Peru.
Formerly treated as a race of S. magellanicus. Related to S.schulenbergi and S. simonsi, and apparently also to two undescribed species from SC Peru (one at 3450-3650 m in Pasco, one at 3000-4000 m in Apurímac). Monotypic.
Distribution: Andes of EC Peru in S Cordillera Vilcabamba.
- Least Concern Enlarge map
Videos1 video
Male and Adult calling Locality Mollepata, Inca Trail, Cusco Department, Peru
Miguel Lezama 2 January 2015 1 year ago 14 sec 4.8
Photos0 photos
- No photographs available yet
Sounds0 recordings
- No sound recordings available yet


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Parallels Desktop for Mac is simply the world's bestselling, top-rated, and most trusted solution for running Windows applications on your Mac. With Parallels Desktop for Mac, you can seamlessly run both Windows and Mac OS X applications side-by-side without rebooting. Drag-and-drop files between Windows and Mac applications, launch Windows applications from your Mac dock, and do much more with speed, control and confidence.
Filter Results
Outlook on MAC OSX
This review is from: Parallels Desktop for Mac 6
Pros: Runs smoothly on 13" MBP 2010 w/ 8GB RAM 10.6.8. Windows 7 64 runs about as fast as an average windows machine. You can lock a USB device to a specific OS!
Cons: Does not always tab through open windows smoothly. Sometimes have to minimize open windows to see dialog boxes.
Other Thoughts: Parallels 6 ran smoothly for me and did what I needed. I got the free upgrade to Parallels 7 and did not notice any real changes. I don't play games, this is for work. In that regard, if you have USB gear that only works in Windows, this has a great feature that allows you to "lock" a device to a particular OS whenever you connect. This is great for my job as I have to connect to proprietary USB devices that only have Windows configuration software. I remember trying this in Parallels version 3/4 and it never worked...finally it does!
Did you find this review helpful?
Takes too much resources
This review is from: Parallels Desktop for Mac 6
Pros: Able to run Windows without restarting.
Cons: Im running a MB Pro with a 2.7ghz i7 with 8gb of RAM and once I open Parallels the whole computer runs sluggish. I capped the program to only use 2GB of RAM and it keeps eating more and more RAM. When you close the program it does not release the RAM it used until you restart your computer.
Other Thoughts: VirtualBox is free and it runs much smoother than Parallels which I paid for. I heard the memory leaking is fixed in 7 but Im not paying an extra 50 dollars to maybe fix their program issue especially when VirtualBox does all I need to do.
Did you find this review helpful?
Gotta Have
This review is from: Parallels Desktop for Mac 6
Pros: It lets you run windows apps along side OS X
Cons: I have no cons with this software
Other Thoughts: if you're moving from pc to mac this is a gotta have, and even if your all mac but want to enjoy all that Windows goodness, this application makes it as easy as 1, 2, 3.
Did you find this review helpful?
Needs RAM for sure!
This review is from: Parallels Desktop for Mac 6
Pros: Version 6 runs on Lion 10.7 stable. Boots Windows 7 pretty fast. Did I mention its Stable?Running out of Pro's
Cons: Needs plenty of RAM to run well. Also fast CPU above 2.0Ghz core 2 or better. The more you try and do the slower it gets.
Other Thoughts: I upgraded to Lion 10.7 and it required me to upgrade from Parallels 5 to 6. I thought 5 ran pretty well in Snow Leopard even with only 2Gb RAM on my Macbook Air. Trouble is it really requires more in Lion. I think because right off the bat the Macbook Air holds 256MB for Graphics memory in system. Then OS X uses about 700MB running. So Parallels running Windows 7 really zaps all the RAM. I only use a browser in Windows 7( my work requires IE8) But even so I get a few tabs open and it starts slowing down. Considering that Parallels says minimum RAM is 1GB for system but even Microsoft recommends 1Gb of RAM for Windows 2GB is now tpyical for good performance. That tells me that Parallels is really skimping on RAM. My advice is Parallels is good if you have 4GB RAM or better. If you don't, go with Boot Camp.
Did you find this review helpful?
This review is from: Parallels Desktop for Mac 6
Pros: Parallels is a great program and I've been nothing but pleased with the speed and ease with which I've set up my VMs. It's amazing that I'm running my full old Windows machine in a window on my Mac, and running everything well!
Cons: None. So far it's doing exactly what I need it to.
Other Thoughts: This is the first time I've been disappointed in Newegg, everything arrived on time but was shipped in an envelope and the package was pretty thoroughly crushed. Then just now I finally received an email confirming my order had been placed, 4 days after it had been delivered! Not what I'd expect from what used to be the best tech store on the internet.
Did you find this review helpful?
Does what it claims
This review is from: Parallels Desktop for Mac 6
Pros: Installed with no problems, various options such as Coherence mode, full screen and windowed all work fine. Installed Windows 7 home premium 64 bit with no problems. I also installed the Chrome OS virtual machine to see what that looks like!
Cons: none
Other Thoughts: I think the price for upgrades as they become available are on the expensive side.
Did you find this review helpful?
This review is from: Parallels Desktop for Mac 6
Pros: You are not limited to just one additional operating system in case you want to use a version of Linux, Windows, and Snow Leopard on the computer
Cons: Windows 7 is somewhat slower compared to using it on a PC.
Other Thoughts: This is an excellent product. Despite other comments if you follow the directions there should be no problems. Read the directions first.
Did you find this review helpful?
Its like your not even using Windows
This review is from: Parallels Desktop for Mac 6
Pros: easy install. Run windows programs just like its an osx app, its like your not even using windows. Its super easy to use, trust me i'm no computer genius by any means, if i can use this with it being this simple anyone should be able to.
Cons: none so far!
Other Thoughts: Not sure why others are having problems. Installed Parallels 6 with Windows 7 professional on my new macbook pro 13 and haven't had a single problem.
2 out of 3 people found this review helpful. Did you?
Awful outsourced support
This review is from: Parallels Desktop for Mac 6
Pros: If you never have a problem and can find solutions in forums, you will be happy because you will never have to deal with their support.
Cons: Support wasted hours of my time. Either the guy was not listening or did not understand my problem. I stated and re-stated clearly what I needed to do. He remoted in to my computer and poked around and couldn't figure it out (nice job, using the free version of teamviewer for commercial use btw). Then he sent me a follow up message blaming me for the problem I was having and saying that the ticket will be open until I close it as resolved. My only option when I log in is to click "resolved" btw.
Other Thoughts: I wish I had started out using some other virtualization software instead.
3 out of 5 people found this review helpful. Did you?
This review is from: Parallels Desktop for Mac 6
Pros: Runs Windows & smoothly and without issues. You can run Windows in cherence mode su you sont really have to go into Windows to use your programs. The programs just open like they would on your Mac.
Cons: It's a bit slow starting up.
Other Thoughts: Works WONDERFULLY on my late 2009 white MACBOOK!! I'm not sure what the other two guys are doing so that Parallels doesnt work, but it works flawlessly in my Mac..
1 out of 3 people found this review helpful. Did you?
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Purple Iris Dream Kanzashi by SincerelyLoveWatch
©2014-2016 SincerelyLove
Rich, elegant colors and extravagant detail combine to make this design a truly eye-catching statement piece. At its center is a multilayered ayame (iris) flower, one of the most iconic motifs of the month of May. Framing it are three adorable flowers in lavender and light green, two jeweled butterflies, and extra multicolored mizuhiki cord decorations in green and purple and silver. Three long shidare falls trail beneath it in lavender and violet, and the whole piece is finished off with deep violet gems and small tinkling bells. Mounted on an alligator clip for easy wear.
More kanzashi for sale HERE!
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Daily DeviationGiven 2015-03-11
Purple Iris Dream Kanzashi by SincerelyLove ( Suggested by cloe-patra and Featured by Erzsabet )
I love the purple colors nice
Congrats on DD!
So pretty and elegant (:
Nice art
Well done! Congrats on the DD
very pretty! nice job.
This is seriously beautiful! Congrats on the DD
Gorgeous! I adore the colors! Congrats on the DD!
So beautiful!
stunning work
Beautiful! Congratulations on your DD!
I'm always in love with everything you make, I love the little butterflies in this one.
Thank you for your kind words, as always! ^_^ I really really appreciate it, and I'm glad you enjoy my work~
That's so beautiful! I love how you did that. Its amazing!
Another gorgeous piece of work. I like how the petles come down on 3 chains like that. The butterfly's are a great touch too.
Very beautiful. I especially love the detail on the main flower.
It is a wonderful piece, I love all the little details
this is incredibly beautiful and the craftsmanship is exquisite!
Wow that is stunning
So pretty!
Oh my! This is so lovely! Wonderful!
really beautiful!
You are so talented
This is so beautiful! I love the colors used!


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I have the '95 jimmy leaking the coolant,I replaced the heater core, and it's ok. It's leak is coming down from on top of the oil pan somewhere, any ideas would help I'm stupped and having a little bad car luck. Thanks!
by dee27ruby in New Castle, PA on January 29, 2009


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Just add sun. For the soothing sound of water and the joyful beauty of nature in your garden, place this birdbath fountain in direct sunlight and enjoy. Its patented, integral underwater solar panel and pump system recycle water from a hidden reservoir, so there are no wires or operating costs. From Smart Solar.
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M26300 — Solar Powered Birdbath Fountain with Decorative Bird by Smart Solar
To choose your shipping method, add this item to your Shopping Cart, continue to Standard Checkout, and make your selection on the Shipping Method page.
Smart Solar
18' Floral Solar Light String Set by Smart Solar
Decorative 32" Garden Solar Metal Swan by Smart Solar
Duck Family with Umbrella Fountain by Smart Solar
Single Tier Solar Powered Ceramic Fountain by Smart Solar
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Browsing by Subject "open educational resources"
Now showing items 1-8 of 8
COERLL Newsletter: Emerging Practices for an Open World, Spring 2015 (COERLL, 2015-04-22)Features include "Introduction to the TELL Project", "Interviews with the TELL Project Team", and "COERLL Highlights 2010-2014 Infographic."
COERLL Newsletter: Research for an Open World, Spring 2014 (2014-04-01)Features include "Open Research, Analytics and the Future of OER", "An Interview with Rob Farrow of the OER Research Hub", and "Report from ACTFL 2013."
How to Search for Openly Licensed Educational Resources (2014-01-08)The growing body of online educational resources is helping to create universal access to language education. This is a good thing. However, finding openly licensed educational resources (OER)—which can be edited, built ...
Open Educational Resources: The Basics (2014-04-01)This convenient, printable fact sheet contains basic introductory information about Open Educational Resources (OER). It briefly defines OER, explains why open licenses are important to OER, lists the potential benefits ...


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Northbound and Northgate embroiled in battle of the brands
Bites and brews at Northbound brewpub: Who has the right to be true north?
Emily Utne
There's a bit of a battle going on between two local breweries, but oddly enough it's got nothing to do with beer.
Northbound's owners Bryce Strickler, Amy Johnson, and Jamie Robinson write: "We have an obligation to protect our trademark, otherwise we'd lose it. We have only asked that the owners of the yet-to-be-opened Northgate Brewing tweak their name to reduce the number of instances of confusion that have already happened."
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Welcome to Audiko.net! Here is a chance to download a free idan raichel project ringtones for your iPhone or mobile. Suit yourself your favorite moments from your favorite tune - Mi'Ma'amakim, Todas las Palabras, rov hashaot, or any other track. Then download the prepared idan raichel project ringtones to your device, and enjoy Hebrew music by idan raichel project every time your phone rings. If you prefer Hebrew or maybe World and Israeli music, then you will probably like hdag nachash, shlomo artzi, or Idan Raichel as well. For all who want a free idan raichel project ringtone, we also recommend listening to israel, Amharic, and . Here you can have your ringtone both in the MP3 and m4a formats, supported by both mobile phones and iPhones. Just select a track, and choose free idan raichel project ringtones download option.
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227/59 Pattaya-Nuklua Road Soi 16/2 gorkai,Banglamung, Wongamat Beach, Pattaya, Thailand 20150
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Wordpress business website design and development
This project received 123 bids from talented freelancers with an average bid price of $1132 USD.Get free quotes for a project like this
Skills Required
Project Budget$750 - $1500 USD
Total Bids123
Project Description
Design and develop a wordpress site for my business. It's a management consulting business. Pretty simple website - pages for Home, Services, Clients, About and Insight (blog). I would like to take advantage of Wordpress' design capabilities (sliders, portfolio, etc.), and the data-driven content so that I can easily revise/extend, as well as have a blog. It must be responsive (mobile-friendly). I have a very rough wireframe in powerpoint, with most of the copy written. (I will provide this as we get further into the decision process.)
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Chicken Balls Recipe
|Chicken Balls Recipe
|Preparation Time
|10 Minutes
|Cooking Time
|20 Minutes
|Recipe Type
|Non Veg.
- 1 tbsp Vegetable Oil
- 1 small Onion (chopped)
- 455 g Chicken (ground)
- 3 cups Biscuit Baking Mix
- 360 g Colby-Monterey Jack Cheese (shredded)
- 1 tsp Garlic (minced)
- ½ tsp Red Pepper Flakes (crushed)
How to make Chicken Balls:
- Preheat oven to 350 °F.
- Heat oil in a pan and shallow fry onion until transparent.
- Mix fried onion with chicken, biscuit baking mix, cheese, garlic, and red pepper flakes in a large mixing bowl.
- Shape the mixture into 1 inch balls.
- Place the balls in a baking pan and bake for 15-20 minutes, or until brown.
- Serve hot.