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How many words can you make with the same five letter choices that come up on the hand held game machine? Tap the letters and give it a twist and make as many words as possible before the timer runs out. You get 3 points for 3 letter words, 5 points for four letter words and 7 points for five letter words. You can play Solo, set it for two players on Turbo, or set it for Party for 2-8 players that gets passed around a circle. If the word is good the machine will play a �you got it� sound. If it�s not good you will see all X�s on the screen. Take this along for waiting games in the car or elsewhere. 8 & up.
Age: Later School Years, Tweens, Teens. Award Year: 2015. Click here to purchase the product on Amazon.com.
They call this a towering game of strategy and luck and that is a good description of a challenging but entertaining fast-paced game. Players try to be first to the top of the tall tower without getting sabotaged by opponents who can send them down or even knock them off. The going back down feels a bit like Candy Land! Our testers and their parents gave this a 5+ rating, which says a lot, since they are regular game testers. It does require a fair amount of sportsmanship when your playing pieces get knocked down, so it may be better to play as teams or play this with the older members of the family. 8 & up. Almost all of our families raved about this toy including: "BEST game we have ever played as a family."
Age: Later School Years, Tweens. Award Year: 2015. Click here to purchase the product on Amazon.com.
A challenging strategy game that calls for visual thinking and planning. Players take turns arranging their color-coded sharks from tail to snout without getting surrounded by other sharks. Players can only place a shark that is pointing to a blank space and not where another shark is pointing. The object is to trap others and keep finding space to swim free. Our older testers loved it. for 2-4 players. 8 & up.
Age: Later School Years. Award Year: 2015. Click here to purchase the product on Amazon.com.
Our testers were hilarious as they played this movable maze game trying to get the hex bug into a trap on their side of the board. Before you can play you do have to set up the maze with moveable forks and spoons; this is a one-time set up but may require adult help. After that you are ready to play as often as you like. Players take turns rolling the die and get to move either a fork or spoon gateway to get the hexbug trapped. There's just one hexbug to the set, but it might be fun to add a few more, should you happen to be very fond of these little buggers that scurry in a hurry. A fast action game that calls for some strategy, a big dose of luck and a lot of laughter. 6 & up
Age: Early School Years, Later School Years. Award Year: 2014. Click here to purchase the product on Amazon.com.
We like this unusual multi-generational game that will be fun for a family occasions since it calls for a lot of talking and sharing of family stories. Players must collect six different colored cards that are drawn randomly from the pile. The tasks on the cards require players to tell about themselves or things they know about other players in the game. For example one task card asks a player to name "all my cousins from oldest to youngest" or to tell "an object I could not live without" or "three places where we have relatives." There are a few picture cards, too, that are supposed to evoke family stories that relate to your family. An uncomplicated game that is likely to produce good laughs and happy memories, this is designed for 3-7 players ages 6-99.
Age: Early School Years, Later School Years, Tweens, Teens, Adult. Award Year: 2015. Click here to purchase the product on Amazon.com.
A game for listening, thinking fast and rapid recall. The game comes with 200 cards with lists and categories. With List cards players race to name three more things that fit the category. With category cards players listen to the list read and try to be the first to name the category. In the Lightening Round players take turns naming things that fall into the category. But be careful, if you guess wrong or name something that was already read on the list, you are out! 8 & up.
Age: Later School Years, Tweens. Award Year: 2015. Click here to purchase the product on Amazon.com.
Need a gift for Grandma or Grandpa for a family celebration? This version of the original game comes with retro cards and money, wooden hotels and houses, and tokens that were used by grandparents, parents and kids from the 30's to the Millennium. A perfect choice for keeping some of the crowd quiet and engrossed at your next family reunion. There is a fancier version of this with golden playing pieces. Game play and playing pieces are otherwise the same. 8 & up.
Age: Early School Years, Later School Years, Tweens, Teens, Adult. Award Year: 2015. Click here to purchase the product on Amazon.com.
The new My Monopoly board game allows you to create a personalized Monopoly game, but, as our testors told us, it's not that easy to do. You can download the free My Monopoly app or visit www.mymonopoly.com to set up an account and personalize property spaces, game tokens, Community Chest and Chance cards to use in the My Monopoly board game. Choose your own photos from your computer or smart device and add captions to the photos. Then, you need to print them out on the sticker sheets, and you are ready to play. Our test families loved the concept, but found doing all these so-called simple steps a real challenge, that took too much stress, time and fun out of the fun. For all but the most savvy computer-able players, stick to Boardwalk.
Age: Later School Years, Tweens, Teens, Adult. Award Year: 2014. Click here to purchase the product on Amazon.com.
This relative newcomer to toyland with over a BILLION dollars in sales has engaged younger kids to the world of gaming with action figures that exist both virtually and as toys. Here's the story: "Kaos has blown up the walls of Cloudcracker Prison and freed notorious villains in Skylands. You and the Skylanders must hunt them down and capture them with magical Traptanium, a powerful material that can harness the Elements. Available for all gaming systems. 6 & up. Editors' Note: While we acknowledge that this is a large and growing segment of toyland, we still wish that the games and technology were less about combat. On the other hand playing these types of games often becomes a social issue - in which case we suggest that you sit down and experience the game play with your child. And as with all "screen" time we suggest you put a time limit on this type of play before you bring the toy home. This type of play should not replace everything else like building, being active and creative in the real world.
Age: Later School Years, Tweens. Award Year: 2014. Click here to purchase the product on Amazon.com.
Our testers found playing against the timer a challenge. Word games are played by laying out a grid of 13 letter tiles, turn the 60 second timer and each player makes a list of as many words as they can see by using letters that connect in any direction. You can ever repeat the same letters, just as long as they continue to connect. When time is up players read their word lists and cross out words that others also found. You get points for any words that you alone were able to find. It's a bit like Boggle without the frame and box and with bonus rings for bonus points. 10 & up.
Age: Later School Years, Tweens, Teens, Adult. Award Year: 2014. Click here to purchase the product on Amazon.com.
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Welcome to the National Academy Championship Horse Show
October 28-30, 2016
Three Days • Three Judges • The Best Academy Riders in the Nation
Download an Entry
Entry forms for our 2015 show are now available. Click here to download our entry pack which contains an entry form for riders, Horse of the Year award form, sponsor form and Good Luck ad form.
Find a Hotel
There are many hotel options for our riders and their families in the Murfreesboro area. Our advice is always to book early. Click here for more information on hotels.
Nominate a Horse
Nominate your favorite horse to win the Academy National "Horse of the Year" Award. All entries are due by September 26, 2015. For an entry form, click here.
Design a Good Luck Ad
Barns, parents and grandparents can help show their support for their riders and the National Academy Championship Horse Show by purchasing a good luck ad. Ads are due by September 26, 2015. Click here for more information.
We're Looking for the Best Academy Riders in the Country
The National Academy Championship Horse Show is one like no other. This is the only 3-day, 3-judge academy show in the nation. Riders from all over the country join us each year in the spirit of competition and to raise money to St. Jude Children's Research Hospital. If you have what it takes to compete with the best, we hope you'll join us October 30-November 1, 2015 in Murfreesboro, TN.
3-Days, 3 Judges ... This is an Academy Show Like No Other
The National Academy Championship Horse Show is unlike any other academy horse show in the nation. Our riders are tested round after round and hope to continue to the final rounds for our biggest prizes. And we're the only show in the nation that has raised over $250,000 to help kids at St. Jude Children's Research Hospital. Come join us and meet other riders with the same passion that you have for horses and for helping others.
Big Competition. Big Prizes.
How would you like to win a new saddle? Or the biggest ribbons you've ever seen?! Our competition is unlike any other. The competition at NACHS may be more than you're ever experienced. More skilled riders to compete against, more to aim for. Come join us and be part of the academy riding event that takes riders to the next level and supports research at St. Jude's. There's no show like this in the nation. And we want you to be part of it.


text: Posted November 23, 2013 Mark Price, one of the best shooters in NBA history is an assistant coach on this team yet charlotte is the worst team in the league in regards to shooting. This is easy. McRoberts is a horrible shooter, and he pretty much negates any double teams that hypothetically Al Jefferson (whose out of shape) should draw. McRoberts, while good at ball handling for a big man and passing presents hardly 0 offensive threat. I can't tell you how much I've seen him miss both 3's and especially lay ups. All his moving without the ball and passes means nothing if he can't make the defense respect him by knocking down shots. So when McRoberts is on the floor it pretty much allows the opposing PF to double down on Jefferson or double Henderson when he tries his elbow jumpers. This is why we drafted Zeller, but he's playing stiff and sort of got a deer in the head lights thing going on right now. He's a rookie so it's understandable but still it's annoying. Ideally we should matchup a mid range PF with some deep ball ability with Al Jefferson (which McRoberts is supposed to be). Because Al Jefferson is primarily an on the block post player, having two low post scorers would pretty much clog offensive passing lanes, create spacing issues for offensive sets, and generally make it easier to collapse on Al when he gets the ball on the low block. All this is forcing our guards and 3 wingers to bear the brunt of the shooting burden. But our guards are asked to do a lot and it's hard for them to shoot over 50% night in and night out especially when defenses know they're our primary scoring option. This is where Clifford has done a good job stressing our guards and forwards to try and get to the charity stripe....which is why we're a .500 team to begin with. After watching this team, especially after tonight against the Suns here is what I think we need to do this coming off season...... *The Al Jefferson signing was a bad signing. We're a team that can run the floor and he can't. We need to let him get his numbers and then try to trade him. *We need to find a way to get McRoberts off the books. *We need to find one more PG since Kemba and Sessions are asked to do a lot. *We need to see if we can lure an athletic big in FA, and I wouldn't be opposed to pulling off some Gettle Magic and double down on big men in the draft. *I think we can all see we're not going to win a playoff series this year. Best case scenario....swept first round as an 8th seed. So it's important to not play ourselves out of the lottery or draft picks this year. Either way we're looking at a highly forgettable season. Might as well have a memorable one next year. Share this post Link to post Share on other sites


text: Mill Plain — Girl Scouts Becca Thompson and Synthia Gifford, who just finished their junior year in high school — Thompson at Mountain View and Gifford at Union — taught cultural art classes about different nations this year to third-graders at Mill Plain Elementary School. Each lesson covered everything from children's lives to traditional food, and the Mill Plain students did an art project of their own in conjunction with each culture. For Brazil, it was Mardi Gras masks. France was stained-glass candleholders, Turkey was mosaics and Australia was painted boomerangs. The effort won Thompson and Gifford their Gold Awards, the highest service award available for Girl Scouts. They hope to do it again next year with more third-grade classes.


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Are you Michiel E Stegenga?Claim your profile
Publications (12)60.41 Total impact
Article: Erythrocyte glutathione concentration and production during hyperinsulinemia, hyperglycemia, and endotoxemia in healthy humans[Show abstract] [Hide abstract] ABSTRACT: In diabetes mellitus and sepsis, low erythrocyte glutathione (GSH) concentrations are found. Whether this is caused by lowered GSH production has not been clarified. To obtain insight in the relationship between erythrocyte GSH concentrations and GSH production, GSH kinetics were measured in healthy male volunteers during 4 different clamps (low-dose or medium-dose insulin [100 or 400 pmol/L] and euglycemia or hyperglycemia [5 or 12 mmol/L]) in a control setting (n = 6; all 4 clamps in the same subject) or after systemic administration of lipopolysaccharide (to mimic sepsis) (4 groups of n = 6; each clamp in a different subject). Hyperinsulinemia decreased erythrocyte GSH concentration (P = .042), but did not affect fractional synthetic rate (FSR) of GSH. Hyperglycemia did not affect erythrocyte GSH concentration, but decreased FSR of GSH (P = .025). Lipopolysaccharide decreased erythrocyte GSH concentration (P < .001), but increased FSR of erythrocyte GSH (P = .035). Depending on the metabolic circumstances, we found either stable GSH concentrations with lower production rates or decreased levels with either no change or an increase in production rate. Based upon these data, it seems inappropriate to infer conclusions about changes in synthesis rate of GSH from changes in its concentration.
Article: Aortic Cross-Clamping and Reperfusion in Pigs Reduces Microvascular Oxygenation by Altered Systemic and Regional Blood Flow Distribution[Show abstract] [Hide abstract] ABSTRACT: In this study, we tested the hypothesis that aortic cross-clamping (ACC) and reperfusion cause distributive alterations of oxygenation and perfusion in the microcirculation of the gut and kidneys despite normal systemic hemodynamics and oxygenation. Fifteen anesthetized pigs were randomized between an ACC group (n = 10), undergoing 45 minutes of aortic clamping above the superior mesenteric artery, and a time-matched sham surgery control group (n = 5). Systemic, intestinal, and renal hemodynamics and oxygenation variables were monitored during 4 hours of reperfusion. Microvascular oxygen partial pressure (microPo(2)) was measured in the intestinal serosa and mucosa and the renal cortex, using the Pd-porphyrin phosphorescence technique. Intestinal luminal Pco(2) was determined by air tonometry and the serosal microvascular flow by orthogonal polarization spectral imaging. Organ blood flow and renal and intestinal microPo(2) decreased significantly during ACC, whereas the intestinal oxygen extraction and Pco(2) gap increased. The intestinal response to reperfusion after ACC was a sustained reactive hyperemia but no such effect was seen in the kidney. Despite a sustained high intestinal O(2) delivery, serosal microPo(2) (median [range], 49 mm Hg [41-67 mm Hg] versus 37 mm Hg [27-41 mm Hg]; P < 0.05 baseline versus 4 hours reperfusion) and the absolute number of perfused microvessels decreased along with an increased intestinal Pco(2) gap (17 mm Hg [10-19 mm Hg] versus 23 mm Hg [19-30 mm Hg]; P < 0.05). In contrast, the kidney showed a progressive O(2) delivery decrease accompanied by a decrease in renal cortex oxygenation (70 mm Hg [52-93 mm Hg] versus 57 mm Hg [33-64 mm Hg]; P < 0.05). Increased systemic and regional blood flow and oxygen supply after ACC does not ensure adequate regional blood flow and microcirculatory oxygenation in all organs.
Article: The thiazolidinedione ciglitazone reduces bacterial outgrowth and early inflammation during Streptococcus pneumoniae pneumonia in mice[Show abstract] [Hide abstract] ABSTRACT: Thiazolidinediones (TZDs) are synthetic agonists for the peroxisome proliferator-activating receptor-gamma receptor and are currently in use as oral glucose-lowering drugs. TZDs have immune-modulating effects in vitro and in vivo. Because patients with type 2 diabetes have an increased risk for pneumonia, we evaluated the influence of ciglitazone, a TZD, on markers of inflammation and outcome during pneumonia caused by Streptococcus pneumoniae. In vivo animal study and in vitro study. University research laboratory. Female C57Bl/6 mice and murine alveolar macrophage-like MH-S cells. C57Bl/6 mice were inoculated with 10 colony-forming units of S. pneumoniae intranasally. The following interventions were studied: 1) vehicle at t = 0; 2) ciglitazone 5 mg/kg intraperitoneally at t = 0; and 3) ciglitazone 5 mg/kg intraperitoneally at t = 0 and 24 hours. Mice were killed at either 24 or 48 hours after infection. Additionally, phagocytosis and killing of S. pneumoniae by MH-S cells were assessed in vitro. Single treatment with ciglitazone reduced bacterial loads at 24 hours but not at 48 hours, whereas repeated ciglitazone treatment did diminish bacterial loads at 48 hours. After 24 hours, cytokine levels in lung homogenate were lower in single-dose ciglitazone-treated mice; however, after 48 hours, there was no difference in lung cytokines between any of the experimental groups. Repeated ciglitazone treatment was associated with less pulmonary inflammation, as judged by histologic examination. On both time points, there was no difference in plasma cytokine levels or lung myeloperoxidase levels between experimental groups. In an additional experiment, ciglitazone treatment (given once daily) tended to reduce mortality. Ciglitazone did not influence phagocytosis or killing of S. pneumoniae by murine alveolar macrophages. Ciglitazone reduces bacterial outgrowth and local inflammation at least during the early stage of S. pneumoniae pneumonia in mice.
Article: Stegenga ME, Vincent JL, Vail GM, et al. Diabetes does not alter mortality or hemostatic and inflammatory responses in patients with severe sepsis[Show abstract] [Hide abstract] ABSTRACT: Diabetes patients have an increased risk of sepsis. Several inflammatory and coagulant pathways that are activated during sepsis are also up-regulated in diabetes patients. We tested our a priori hypothesis that the presence of diabetes adversely affects the outcome of sepsis. Retrospective analysis of a previously published study. Intensive care units of 164 centers in 11 countries. Eight hundred thirty severe sepsis patients who were admitted to the intensive care unit and who received standard critical care treatment. Patients were stratified into diabetic and nondiabetic patient groups. Mortality was assessed after 28 and 90 days, causative microorganisms were evaluated, and markers of coagulation, fibrinolysis, and inflammation were measured at several time points. Diabetes was present in 22.7% of all sepsis patients. Throughout the study, plasma glucose levels were higher in diabetic patients. Mortality was equal in diabetic and nondiabetic patients (31.4% vs. 30.5% after 28 days). Markers of coagulation, fibrinolysis, and inflammation were generally equal in diabetic and nondiabetic patients, although on admission diabetic patients had slightly higher levels of anticoagulation markers. Interestingly, nondiabetic patients with admission hyperglycemia (>11.1 mmol/L; 200 mg/dL) had a higher mortality rate compared to those without admission hyperglycemia (43.0% vs. 27.2%). Although diabetes is a risk factor for sepsis, once established, the outcome of severe sepsis does not appear to be significantly influenced by the presence of diabetes. In nondiabetic patients, however, admission hyperglycemia is associated with an increased mortality.
- [Show abstract] [Hide abstract] ABSTRACT: Sepsis-induced hypoglycemia is a well known, but rare, event of unknown origin. The aim of the study was to obtain insight into the mechanism of sepsis-induced hypoglycemia, focusing on glucose kinetics and insulin sensitivity measured with stable isotopes by using the model of human endotoxemia. Glucose metabolism was measured during two hyperinsulinemic [insulin levels of 100 pmol/liter (low-dose clamp) and 400 pmol/liter (medium-dose clamp)] euglycemic (5 mmol/liter) clamps on two occasions: without or with lipopolysaccharide (LPS). The study was conducted at the Academic Medical Center, Metabolic and Clinical Research Unit (Amsterdam, The Netherlands). Eighteen healthy male volunteers participated in the study. A hyperinsulinemic euglycemic (5 mmol/liter) clamp with LPS (two groups of six subjects; insulin infusion at rates of either 10 or 40 mU.m(-2).min(-1)) or without LPS (n = 6; both insulin infusions in same subjects). We measured hepatic and peripheral insulin sensitivity. Hepatic insulin sensitivity, defined as a decrease in endogenous glucose production during hyperinsulinemia (100 pmol/liter), was higher in the LPS group compared to the control group (P = 0.010). Insulin-stimulated peripheral glucose uptake was higher in both clamps after LPS compared to the control setting (P = 0.006 and 0.010), despite a significant increase in the plasma concentrations of norepinephrine and cytokines in the LPS group during both clamps. These data indicate that shortly (2 h) after administration of LPS, peripheral and hepatic insulin sensitivity increase. This may contribute to the hypoglycemia occurring in some patients with critical illness, especially in the setting of intensive insulin therapy.
Article: Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia, inhibits fibrinolysis during human endotoxemia[Show abstract] [Hide abstract] ABSTRACT: Type 2 diabetes is associated with altered immune and hemostatic responses. We investigated the selective effects of hyperglycemia and hyperinsulinemia on innate immune, coagulation, and fibrinolytic responses during systemic inflammation. Twenty-four healthy humans were studied for 8 hours during clamp experiments in which either plasma glucose, insulin, both, or none was increased, depending on randomization. Target plasma concentrations were 5 versus 12 mM for glucose, and 100 versus 400 pmol/L for insulin. After 3 hours, 4 ng/kg Escherichia coli endotoxin was injected intravenously to induce a systemic inflammatory and procoagulant response. Endotoxin administration induced cytokine release, activation of neutrophils, endothelium and coagulation, and inhibition of fibrinolysis. Hyperglycemia reduced neutrophil degranulation (plasma elastase levels, P < .001) and exaggerated coagulation (plasma concentrations of thrombin-antithrombin complexes and soluble tissue factor, both P < .001). Hyperinsulinemia attenuated fibrinolytic activity due to elevated plasminogen activator-inhibitor-1 levels (P < .001). Endothelial cell activation markers and cytokine concentrations did not differ between clamps. We conclude that in humans with systemic inflammation induced by intravenous endotoxin administration hyperglycemia impairs neutrophil degranulation and potentiates coagulation, whereas hyperinsulinemia inhibits fibrinolysis. These data suggest that type 2 diabetes patients may be especially vulnerable to prothrombotic events during inflammatory states.
Article: Hyperglycemia prevents the suppressive effect of hyperinsulinemia on plasma adiponectin levels in healthy humans[Show abstract] [Hide abstract] ABSTRACT: Adiponectin is a fat-derived hormone with insulin-sensitizing properties. In patients with type 2 diabetes plasma adiponectin levels are decreased. Since these patients are characterized by high plasma insulin and glucose concentrations, hyperinsulinemia and hyperglycemia could be responsible for the downregulation of adiponectin. Insulin decreases adiponectin levels in humans. The effect of hyperglycemia is unknown. To determine the selective effects of insulin, glucose, or their combination on plasma adiponectin, clamps were performed in six healthy males on four occasions in a crossover design: 1) lower insulinemic-euglycemic clamp (100 pmol/l insulin, 5 mmol/l glucose) (reference clamp); 2) hyperinsulinemic-euglycemic clamp (400 pmol/l insulin, 5 mmol/l glucose); 3) lower insulinemic-hyperglycemic clamp (100 pmol/l insulin, 12 mmol/l glucose); and 4) hyperinsulinemic-hyperglycemic clamp (400 pmol/l insulin, 12 mmol/l glucose). Adiponectin concentrations and high-molecular-weight (HMW)-to-total adiponectin ratio were measured at the start and end of the 6-h clamps. After the 6-h study period, total plasma adiponectin levels were significantly (P = 0.045) decreased by 0.63 microg/ml in the lower insulinemic-euglycemic clamp (clamp 1). In both euglycemic groups (clamps 1 and 2) adiponectin concentrations significantly declined (P = 0.016) over time by 0.56 microg/ml, whereas there was no change in both hyperglycemic groups (clamps 3 and 4) (P = 0.420). In none of the clamps did the ratio of HMW to total adiponectin change. We conclude that insulin suppresses plasma adiponectin levels already at a plasma insulin concentration of 100 pmol/l. Hyperglycemia prevents the suppressive effect of insulin. This suggests that, in contrast to glucose, insulin could be involved in the downregulation of plasma adiponectin in insulin-resistant patients.
Article: Transgenic tissue-type plasminogen activator expression improves host defense during Klebsiella pneumonia[Show abstract] [Hide abstract] ABSTRACT: Severe pneumonia is associated with a local inhibition of fibrinolysis in the lung as reflected by strongly reduced pulmonary plasminogen activator activity.Objectives: To study the effect of elevation of local plasminogen activator activity during pneumonia caused by the common respiratory pathogen Klebsiella pneumoniae. Female C57Bl/6 mice were inoculated intranasally with a replication-defective adenoviral vector expressing human tissue-type plasminogen activator or a control vector 24 h before intranasal infection with K. pneumoniae. Mice infected with Klebsiella via the airways developed overt pneumonia, which was accompanied by a downregulation of pulmonary tissue-type plasminogen activator levels at protein and mRNA levels. Pulmonary overexpression of human tissue-type plasminogen activator resulted in increased fibrinolytic activity in the lungs during pneumonia, as indicated by higher D-dimer levels and reduced fibrin deposition. Interestingly, overexpression of tissue-type plasminogen activator markedly improved host defense against pneumonia: mice treated with the tissue-type plasminogen activator vector displayed less bacterial growth and dissemination, attenuated distant organ injury and a reduced mortality. These data demonstrate that local elevation of plasminogen activator activity in the lungs improves host defense against severe gram-negative pneumonia and sepsis.
Article: Effect of acute hyperglycaemia and/or hyperinsulinaemia on proinflammatory gene expression, cytokine production and neutrophil function in humans[Show abstract] [Hide abstract] ABSTRACT: Type 2 diabetes is frequently associated with infectious complications. Swift activation of leucocytes is important for an adequate immune response. We determined the selective effects of hyperglycaemia and hyperinsulinaemia on lipopolysaccharide (LPS)-induced proinflammatory gene expression and cytokine production in leucocytes and on neutrophil functions. Six healthy humans were studied on four occasions for 6 h during: (i) lower insulinaemic euglycaemic clamp, (ii) lower insulinaemic hyperglycaemic clamp, (iii) hyperinsulinaemic euglycaemic clamp, and (iv) hyperinsulinaemic hyperglycaemic clamp. Target levels of plasma glucose were 12.0 mmol/l (hyperglycaemic clamps) or 5.0 mmol/l (euglycaemic clamps). Target plasma insulin levels were 400 pmol/l (hyperinsulinaemic clamps) or 100 pmol/l (lower insulinaemic clamps). Hyperglycaemia reduced LPS-induced mRNA expression of nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor alpha (NFKBIA), interleukin-1 alpha (IL1A) and chemokine (C-C motif) ligand 3 (CCL3), whereas during hyperinsulinaemia enhanced mRNA levels occurred in six out of eight measured inflammation-related genes, irrespective of plasma glucose levels. Combined hyperglycaemia and hyperinsulinaemia led to enhanced IL1A, interleukin-1 beta (IL1B) and CCL3 mRNA levels upon LPS stimulation. Neither hyperglycaemia nor hyperinsulinaemia altered cytokine protein production, neutrophil migration, phagocytic capacity or oxidative burst activity. These results suggest that short-term hyperglycaemia and hyperinsulinaemia influence the expression of several inflammatory genes in an opposite direction, that the acute effects of hyperinsulinaemia on inflammatory mRNA levels may be stronger than those of hyperglycaemia, and that the effects of insulin, in particular, may be relevant in the concurrent presence of hyperglycaemia.
Article: Hyperglycemia Stimulates Coagulation, Whereas Hyperinsulinemia Impairs Fibrinolysis in Healthy Humans[Show abstract] [Hide abstract] ABSTRACT: Type 2 diabetes and insulin resistance syndromes are associated with an increased risk for cardiovascular and thrombotic complications. A disturbed balance between coagulation and fibrinolysis has been implicated in the pathogenesis hereof. To determine the selective effects of hyperglycemia and hyperinsulinemia on coagulation and fibrinolysis, six healthy humans were studied on four occasions for 6 h: 1) lower insulinemic-euglycemic clamp, 2) lower insulinemic-hyperglycemic clamp, 3) hyperinsulinemic-euglycemic clamp, and 4) hyperinsulinemic-hyperglycemic clamp. In the hyperglycemic clamps, target levels of plasma glucose were 12 versus 5 mmol/l in the normoglycemic clamps. In the hyperinsulinemic clamps, target plasma insulin levels were 400 versus 100 pmol/l in the lower insulinemic clamps. Hyperglycemia exerted a procoagulant effect irrespective of insulin levels, as reflected by mean twofold rises in thrombin-antithrombin complexes and soluble tissue factor, whereas hyperinsulinemia inhibited fibrinolysis irrespective of glucose levels, as reflected by a decrease in plasminogen activator activity levels due to a mean 2.5-fold rise in plasminogen activator inhibitor type 1. The differential effects of hyperglycemia and hyperinsulinemia suggest that patients with hyperglycemia due to insulin resistance are especially susceptible to thrombotic events by a concurrent insulin-driven impairment of fibrinolysis and a glucose-driven activation of coagulation.
- [Show abstract] [Hide abstract] ABSTRACT: Leptin is a pleiotrophic protein mainly produced by adipocytes that has been implicated as a link between nutritional status and immune function. Severe bacterial infection is associated with elevated plasma levels of leptin. To determine the role of leptin in the host response to bacterial pneumonia leptin deficient ob/ob mice and normal wild-type (WT) mice were intranasally infected with different doses of the Gram-positive pathogen Streptococcus (S.) pneumoniae or the Gram-negative bacterium Klebsiella (K.) pneumoniae. After infection with lower doses of either pathogen ob/ob mice displayed lower pulmonary levels of proinflammatory cytokines, in particular tumor necrosis factor-alpha and chemokines. However, after infection with a higher dose of S. pneumoniae or K. pneumoniae the lung concentrations of these inflammatory mediators did not differ between ob/ob and WT mice. In addition, the extent and severity of lung inflammation, as assessed by semi-quantitative histopathology scores, were similar in both mouse strains. Finally, leptin deficiency did not impact on the bacterial outgrowth in the lungs during either Gram-positive or Gram-negative pneumonia irrespective of the infective dose. These data suggest that although leptin may play a modest role in the regulation of inflammation during bacterial pneumonia, it does not contribute to host defense mechanisms that act to limit the outgrowth of S. pneumoniae or K. pneumoniae in the lower airways.
Article: The influence of hyperglycemia and hyperinsulinemia on innate immune and coagulent responses
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University of Amsterdam
Amsterdam, North Holland, Netherlands
- Faculty of Medicine AMC


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Thomas Suarez:
Thomas·Suarez: 一名12岁的手机应用开发者
很多12左右的孩子都喜欢玩游戏,而12岁的Thomas Suarez则自学成才,创造游戏。在成功地开发了Bustin Jieber(一款类似于"打地鼠"的游戏)等手机应用之后,他现在开始帮助其他的孩子成为应用开发人员。 (拍摄于ManhattanBeach,TEDx)
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Cape Cod Photographers Specializing in Wedding Photography, Portraits, Fashion, and Fun!
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In addition to wedding photography, we also offer great wedding cinematography, making us one of the only full time studios to offer both of these services here on Cape Cod.


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I'm not 100% sure what the saddle i have is made of but it looks a lot like leather. I'm wondering if anyone has found any totally vegan saddles? If so some links would be awesome, thanks.
I'm not 100% sure what the saddle i have is made of but it looks a lot like leather. I'm wondering if anyone has found any totally vegan saddles? If so some links would be awesome, thanks.
synthetic leather is now the norm, not the exception.
yup guess its better to use more energy, create more waste, use more petrochemicals in the manufacturing of a plastic pleather saddle, than to use readily available leather that is natural. And lets be serious here, do you honestly think your plastic saddle is going to make a difference in the grand scheme of the earth, considering that everyday millions of tons of pollutants, billions of tons of garbage are created are dumped back into the earth. (dont forget to add your plastic saddle to that garbage when it wears out, it wont degrade any, unlike a real leather saddle that will degrade properly)
haha, so true.
though mr. vegan probably has a point with how much food / water / energy / land goes into raising cattle.
by the way i'm vegetarian.
There is of course the option of buying a used leather saddle - it'll already be worked in, doesn't contribute to the cycle in the same way and will, in all likelihood, outlive a synthetic saddle by a longshot.
I'm vegan, have been for about 12 years and I ride on a used Terry Fly which is leather - I never lose sleep over it.
Last edited by MattRennick; 08-21-07 at 10:42 PM.
IN REGARDS TO THE OP: I agree with MattRennick^^^ Makes sense to me. Avoid any potentially harmful chemicals in new materials and supporting any inhumane practices associated with the current leather industry. Plus, 'Reuse' is one of the three "Rs", right?
but i like bitter sarcasm...
there are so many more important things to worry about than sacrificing a cow.
do you know how many grass plants the cows kill when theyre chomping? how many birds they kill when farting?
im sure as hell there aren't cows that don't eat.
or maybe there are... FREE ENERGY
if you are a mac n00b, copy this and paste it into your own signature
My current favorite is the fizik aliante sport. It has a synthetic cover and can be found for ~$50 on ebay.
Takin' the first bus out of Shell Town
Huge portions of rich farmland are set aside to grow Monsanto GM corn, then Petroleum-based pesticides are sprayed on the corn, which are then fed to poorly treated, factory-farmed animals whose waste is hugely polluting to local ground waters and our rivers. Meanwhile, the nitrogen-rich fertilizer (required to grow feed-grade corn season after season) runs off into our rivers, where it floats down stream into the ocean, causing massive "dead-zones," which are seriously threatening a number of plant and animal species with extinction. All of this in ignoring the astonishing amount of energy required to raise one cow from birth to slaughter, as well as the disgusting and dangerous chemicals used in tanning leather.
People continue to act like leather saddles are plucked from the ****ing Saddle Tree, while synthetics come from the Once-ler. At best, the difference between the types of material used to cover your saddle is negligible, and claims to the contrary are wholly without merit.
Last edited by bonechilling; 08-21-07 at 11:52 PM.
I haven't found any faux leather saddles, but if yours is leather don't bother throwing it out just because a critter died. That animal is already dead and it's not like you are actively contributing to the industry by keeping a used item. Nobody is going to think less of your vegan-ness just because you happen to be using a leather saddle, and if they get in your face about it, don't bother talking to them because they're being a pretentious nit.
Take good care of your current saddle as not to waste it or let it get weathered+destroyed, if your concern is for the animal's sake, it would probably be offended knowing that it died just so it could be thrown into a landfill! If you really do feel uncomfortable or that it conflicts too much with your beliefs, donate it to another cyclist and see if you can find a comparible one from a local bike shop.
btw, I am a very strict vegetarian, only thing keeping me from going back to vegan is my insatiable love of cheese :]
Very well stated, bonechilling. I heard somewhere that not too far back meat in this country was something that people had on a once a week or once a month basis...not with EVERY meal like it is now days. Too bad I nearly lose control of my salivary glands every time someone puts a Del Monico steak in front of me.
What would have to be done to qualify as a vegan saddle...just that it doesn't use any animal products in the process? I think going into a LBS and asking which saddles use real leather and which ones do not would yield the best results.
^this may or may not be useful information <--this not so much.
slaughter a redneck meat eater and cure their skin and make a saddle from that. that'll make all of us feel so much better. plus, it's the genuine vegan option: only vegetables harmed in the process.
05 Giant TCR Composite; 83 Colnago Saronni; 81 San Rensho Katana Super Export track #A116-56; 97 GT Zaskar; 89 Zunow Pentaglia: SOLD; 85 Tommasini: SOLD; 83 Guerciotti: SOLD
what you plan to eat your saddle?????
bonechilling ftw
but check out the specialized saddles
most fizik's are synthetic also
so is this sexy little biatch
yes to the Fizik's (though I don't like their look), also the Tioga Spyder that pops up on here every once in a while is plastic and well liked (by some), Kashimax made plastic BMX saddles that the fixie kids like here in Tokyo, you could get a fabric covered one--no names except Selle San Marco spring to mind off hand but there are several varieties of kevlar/cordura/embroidery type saddles floating around.
i've been vegan for almost twelve years, no leather for the first 6, then integrated used pieces to my life (started with a practical motorcycle jacket--save my own skin), and then down the slippery slope to buying any leather good my heart desires. still on the vegan wagon food-wise though.....
I am Vegetarian too, it took me a while to decide to get a leather saddle.
Oh and just because a saddle is not made of leather does not make it vegan.
glue creeps into everything..... or are you talking about something else, level-elph?
glue is probably more synth than not these days. or....is it???


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In an interview about her upcoming full length album, British goth pop starlet Charlotte Aitchison attempts to explain the concept behind her performance alias Charli XCX, saying, "that's what Charli XCX is all about: creating a world to get into." The video for her latest single, "You're The One," gives us a peek into this world in her head. An empty warehouse is brought to life with lights, costume changes, hearts, and a clan of little raver girls draped in attitude and leather–perhaps an allusion to Aitchison's roots as a 14-year old taking over the underground UK rave scene.
In the same interview, Charli XCX discusses some of the challenges she's been facing getting the album together, including the apparent regular realization that she and producer Ariel Rechtshaid need to drop everything and go buy soap and/or tequila shotguns. Fortunately, they're pulling it together and plan to have the still unnamed album out by October. In the meantime, load up your tequila shotgun and check out her recently released EP.
Stream: Charli XCX – "You're The One"


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I recently assembled a new computer and installed Windows XP. Installation went fine without any problem but when I started the system and programs loaded, I received an error message saying:
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There was 3 buttons around this pop i.e. Cancel, Try Again, and Continue. No matter what I click, at the next reboot I get this message again. Any idea what could be the problem and how can I fix it? Many thanks.


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A file photo of Bartholomew is available via www.religionnews.com
NEW ORLEANS (RNS) It is the religious duty of Orthodox Christians to protect an environment harmed by natural disasters and society's modern way of life, Ecumenical Patriarch Bartholomew I said here on Wednesday (Oct. 21).
''We are living in a moment in history when we must work for solutions in faith, in love, in hope, and in responsibility," said Bartholomew, who is spiritual leader of nearly 300 million Orthodox Christians worldwide.
Speaking from a balcony overlooking the Mississippi River, the subject of a week-long conference of religious, political and academic leaders convened by the patriarch, Bartholomew kicked off the event by saying that the river is in need of repair — just as the city is.
''The river is a microcosm of our planet," he said. "In the water we observe many of the world's ecological issues."
It is the eighth time Bartholomew — known as the "green patriarch" because of his interest in the intersection of faith and the environment — has convened a conference on the problems facing major bodies of water. Previous gatherings have centered on issues facing the Aegean Sea, the Danube River and the Arctic Ocean.
Bartholomew's stop here is part of an apostolic visit to the United States that lasts until Nov. 6. He has already visited Memphis, Tenn., and heads to Atlanta, New York and Washington, after New Orleans.
The religious leader, based out of Istanbul, has brought worldwide attention to metro New Orleans' post-Hurricane Katrina recovery. He visited the city just four months after the catastrophic flood and told residents rebuilding and gutting their homes, "Your pain was and is our pain. It was felt by all humanity."
After arriving on Tuesday, Bartholomew issued a statement saying, "We return so that we might bear witness to the hope that is in you, the hope you have manifested through the rebuilding (of) your lives and your community."
The environmental symposium will focus particularly on Louisiana's coastal erosion. The Rev. Canon Sally Bingham, who helped organize the meeting, has said the patriarch recognizes that, "while climate change didn't cause the levees to break," it is causing storms and droughts that are more severe.
In his speech introducing the symposium, Bartholomew said that the natural resource of water has been damaged by the demands of modern culture, citing depletion by irrigation systems and the loss of half of the world's rain forests.
''Without thinking, we have lost so much of the sponges responsible for the delivery of our fresh water," he said.
Bartholomew's call for solutions prompted Archbishop Demetrios, the head of the Greek Orthodox Archdiocese of America, to call Bartholomew the "healing patriarch."
''He tends to the wounds inflicted on the world by human causes and natural catastrophes," the archbishop said.
Pope Benedict XVI sent a message to be delivered to symposium attendees expressing his support for environmental work.
Former Vice President Al Gore, who has championed environmental causes since leaving office and was awarded the 2007 Nobel Peace Prize for his efforts, also sent a message congratulating Christians for focusing attention on an issue he believes is in dire need of action.
Dsb/dea END MINKOFF


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Non-State Actors in World Politics
By Daphne Josselin, William Wallace
Non-State Actors in World Politics
By Daphne Josselin, William Wallace
The involvement of non-state actors in world politics can hardly be characterized as novel, but intensifying economic and social exchange and the emergence of new modes of international governance have given them much greater visibility and, many would argue, a more central role. Non-State Actors in World Politics analyzes a diverse range of economic, social, legal (and illegal), old and new actors, such as the Catholic Church, trade unions, diasporas, religious movements, transnational corporations and organized crime.
Related books and articles
- Books
- Journals
- Magazines
- Newspapers
- Encyclopedia
The Management of Non-Governmental Development Organizations: An Introduction By David Lewis Routledge, 2001
Protecting Human Rights in Africa: Roles and Strategies of Non-Governmental Organizations By Claude E. Welch Jr. University of Pennsylvania Press, 1995
Asia-pacific Diplomacy: Nongovernmental Organizations and International Relations By Lawrence T. Woods University of British Columbia Press, 1993
Cultural Competency, Adaptation and Intelligence: Non-Governmental Organizations' Role in This Globalization Era By Ramón, Denise Krohn Journal of Social Research & Policy, Vol. 4, No. 1, July 2013
Peer-reviewed publications on Questia are publications containing articles which were subject to evaluation for accuracy and substance by professional peers of the article's author(s).
Parliament and Civil Society: Globalization and Other Issues of Importance to the Public Are Prompting Non-Governmental Organizations to Become More Active in Shaping Policy Agendas By Augustine, Jean Canadian Parliamentary Review, Vol. 25, No. 1, Spring 2002
Global Civil Society and Inter-Governmental Organizations: The Role of Non-Governmental Organizations in the World Trade Organization By Pandey, Nimisha IUP Journal of International Relations, Vol. 7, No. 1, January 2013
Non-Governmental Organizations: Arafat and ANC's Tambo Address Geneva Conference on Palestine By Betz, Don Washington Report on Middle East Affairs, Vol. XI, No. 5, November 3, 1992
Grass-Roots NGOs Develop Trade: Non-Governmental Organizations Can Bring Complementary Skills, Knowledge and Commitment to Trade Development Projects, Particularly Those Helping Poor Communities By Hulm, Peter de Sousa, Prema Domeisen, Natalie International Trade Forum, No. 2, April-June 2006
Working with NGOs: Focusing on Development Is the Key to Partnership between Trade Agencies and Non-Governmental Organizations By Domeisen, Natalie Towe, Brian International Trade Forum, No. 2, April-June 2006
Environmental Groups Are Given a Voice as Heads of State Prepare for the Rio "Earth Summit," Non-Governmental Environmental Organizations Prepare for Their Own Meeting to Push for Increased International Efforts in Environmental Protection and Natural Resource Management. WORLD ENVIRONMENT By Brad Knickerbocker, writer of The Christian Science Monitor The Christian Science Monitor, March 27, 1992
Thoughts of the Times; Korea on the Wings of Globalization (I) By Korea Times (Seoul, Korea), May 29, 2000
Globalization Foes Weave Own Web of Recruits By Sands, David R. The Washington Times (Washington, DC), April 7, 2000


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Nice concept
clever composition
yeah, it took me a few seconds to see it correctly, but great shot! Very interesting perspective!
Thank you all so much!
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love it!!!!
Lovely image and composition.
Thank you, Ally, Brian, Guido, tarrby & hannes! Really appreciate it!! :) :)
this is fabulous !!!
Glad you like it, bscv!
Terrific image!
Why, thank you :)
Really cool!
Thanx, Nicklas!
Thank you, Bruce! :)
really interesting image
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Thank you, Nourbese!!
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Reviews - Rustington Manor Hotel4
12 Broadmark Lane, Rustington,, Littlehampton, BN16 2HH
Price FromView Rooms
Customer Reviews
Our reviews are from genuine LateRooms.com customers. We verify that the customer has stayed before leaving a review.
100% would recommend it to a friend
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Perfect stay and the food was of the highest standards.
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I stayed for two nights b&b and were made very welcome. The room was clean and roomy, dressing gowns supplied were really nice touch. Breakfast was sufficient I only had continental but other options were available, I would definately stay again, especially if visiting Brighton, only 40 minutes drive away.
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Rustington Manor Hotel
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The room wasn't overlarge but it was very clean and comfortable. I had a good evening meal. The only issue for me was that I couldn't find someone to check me in when I arrived at 5pm.
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Lovely hotel and very friendly staff
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Owners were friendly and obliging.
Hotel 5 mins from shops and sea walking distance. Lovely thick white towels. Comfortable beds. Very hot during our stay but a fan was put in our room.
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Great hotel in excellent location
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The location was great, the hoteliers were very pleasant and the place was very clean and welcoming. The food on offer was lovely too. Would go back.
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Time to head behind the scened with the devs once again in this new video called The Wastland.
In this latest video, the team at id discuss creating the world of RAGE, its variety of intense missions as well as co-op and multiplayer combat rally racing. I'm still not convinced by the racing element myself, not a huge fan of vehicles in games like RAGE but I'm sure id know what they are doing.
Use your site account, social media or Disqus to comment. Select now.


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The calendar says it is, but can it really be? Can 2014 be here already? What happened to 2013? For that matter, what happened to this past decade?
I remember quite well when we were so very concerned about the coming of Y2K. Would we make it through without catastrophic consequences? That day seems like only yesterday, yet 14 years have come and gone seemingly in an instant.
With the new year comes the traditional resolutions, those promises we make to ourselves to somehow make things better. What will it be this year? Eating healthy? Getting more rest? Helping those less fortunate? Perhaps making a difference at work?
Reaching out to the many people in our county who are struggling might be a start if looking for a way to make a difference in 2014.
Many agencies throughout the county offer ways individuals can offer a lending hand. Perhaps you drive and have a day off during the week. Countless seniors depend on others to take them to medical appointments and could certainly use a ride.
Many agencies around the county use a host of volunteers to sort and organize clothing for those less fortunate. Reading a story to a senior citizen in a nursing home who might not otherwise receive visitors might also prove to be rewarding. And what about helping out at your neighborhood school?
There are countless opportunities out there for anyone who has the desire to truly make a difference. While some locations might require a background check to ensure everyone's safety, many places do not.
There is indeed that special place waiting for all of us if we just look around.
It may be as close as the neighbor down the street who lives alone and recently lost her husband or the young mom on the next block who is trying to learn English.
All we have to do is look. The year 2014 just might be that very special year after all.
Carol Edwards is retired after a 30-year career teaching elementary school students at Greenwood schools. Send column ideas to email@example.com.


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Notice: All Boston.com forums will be retired as of May 31st, 2016 and will not be archived. Thank you for your participation in this community, and we hope you continue to enjoy other content at Boston.com.
posted at 4/20/2009 11:18 AM EDTI know that part of the reason this board is not as active as it could be is because of the flawed re-design . . . at least, that's why I don't post as much as I did when I was on the wedding boards, back in the day. It's so frustrating not to have "flagged" messages, # of new posts since you last read it, having the thread pick up where you left off, and not receiving email notifications of replies.
That said, are you all using the BoMoms forum at all? It seems kind of active, but I have no idea who those women are! Are they "real" women like us, or are they fake posts? I guess I just feel like I kind of "got to know" some of the women on here from the wedding boards; at least, I recognize the screen names. But the folks on BoMoms seems like a whole new crew. Thoughts?
posted at 4/20/2009 11:18 AM EDT[Quote]Honestly...I'm not sure either!! I tend to quickly scan the topics - but a lot of them seem to be advertising for something or other and not real meaningful questions/posts that normally show up on this site.[/Quote]
Yeah ... I tend to agree: seems like advertising for the most part. Or that the questions in the forums are posed by the members of the "Motherboard" - the folks in charge of the site.
posted at 4/20/2009 11:18 AM EDTit'sdefinitely the flawed redesign, which is a very nice way to put it :)
the bomoms site is too much fluff for me. all i would like is a normal message board with normal people!
so no, i'm not on the bomoms site at all. it's seems totally useless to me.
posted at 4/20/2009 11:18 AM EDTNo. The topics on BoMoms are generally droll or ridiculous but really, "BoMoms" the term just makes me want to stab my eyes out.
posted at 4/20/2009 11:18 AM EDTHonestly...I'm not sure either!! I tend to quickly scan the topics - but a lot of them seem to be advertising for something or other and not real meaningful questions/posts that normally show up on this site.
Re: BoMoms?
posted at 5/11/2009 3:29 PM EDTCan someone tell me what happened to the "Ask the Experts" section? Or the "Mom Talk" section? What has happened to BoMoms?
New Moms site
posted at 5/12/2009 1:44 PM EDTHi, grace -- We recently redesigned and renamed BoMoms to simply Boston.com Moms. We are using these message boards rather than the separate system in use before, have added a daily mailbag by Barbara Meltz, and are featuring a blogroll of local parenting bloggers.
As for the Ask the Experts feature: We found that the experts weren't answering the questions quickly enough for the parents who had written in, so we've temporarily suspended that feature until we can line up new experts. We're also interested in whether a feature like that would be of interest; your message seems to indicate it would. Anyone else want to weigh in?
Meanwhile, I would appreciate it if you all could check out the new Moms site and tell us what you think. It's a work in progress, so your suggestions are welcome.
Re: BoMoms?
posted at 5/13/2009 1:49 PM EDTHi BDCDottie,Thanks, I am definitely interested in getting the experts back, but you are right, they really didn't answer fast enough. It would be good to get this back again with more experts. I also would love to see a category or more information for moms of grade school age and teenage kids. I'll bet there are other moms out there who would like to have this kind of info included. I've investigated other blogs, but they mostly seem to cater to moms of infants and toddlers. I know that is a big market, but I also believe there is a market for older moms too. Thanks for your help and good luck with improving the site.
Re: BoMoms?
posted at 5/13/2009 4:20 PM EDTI also would love to see a category or more information for moms of grade school age and teenage kids. I'll bet there are other moms out there who would like to have this kind of info included.
Posted by grace
Grace, I feel the same way! I try to address some of those "older-kid" issues in the Child Caring column; please feel free to email me with some of the subjects you'd like to see posted!
-- Lylah
Re: BoMoms?
posted at 5/13/2009 6:38 PM EDTHi, grace, We do include articles suited to all ages of kids on the site, but you're right; there does seem to be more information available for infants and toddlers. I had started a Teens and Tweens category on this Parents Forum at the request of some mothers when I started these boards more than 2 years ago, but it just didn't get much traffic, so I closed it. Happy to start one again if there's a demand for it. And I will definitely look into ramping up the Ask the Experts feature again.
Re: BoMoms?
posted at 5/13/2009 9:28 PM EDTThanks Lylah and BDCDottie. I just read the "Child Caring column" and think it's great. I may post a question sometime regarding older kids if I need to, I have 3 kids ranging in age from 8 to 13! Thanks.


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Susan Wooldridge MS, LCMHC
|Professions: Mental Health Counseling
|License Status: I'm a licensed professional.
|Primary Credential: LCMHC
|Secondary Credential: LPC
Billing and Insurance
Click here to ask this therapist for billing and insurance information.
See other therapists in Stowe, VT.
My approach to helping others is warm, friendly, and professional. I have learned a fair amount about disorders and diagnoses in school/books/trainings, however, I think that the knowledge base I have developed over the years is often the least helpful tool I have in assisting others through their pain. My ability to be present for others in the moment is often what facilitates change. I am most interested in how individuals connect positively to the world around them and what it is that is blocking them from doing so at this time.
I work well with pre-teens,adolescents,and women of all ages. I specialize in working with eating disorders like; anorexia, binge-eating disorder, bulimia and compulsive overeating. Additionally, I like working with families and couples; "No one can challenge us like those we love!"
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I accept most insurances and I am willing to work on a sliding fee scale to be determined on a case by case basis. I also am a Tricare provider and welcome any veterans or military personnel.
What I Love about Being a Psychotherapist
What I love about being a therapist is really fairly selfish on my part. It makes me feel good on a very basic level. It is my belief that one of the reasons we are here on this planet is to help each other. We all need to find our way of doing this and therapy is mine.
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My role as a therapist is to partner with my clients to assist people out of their own dilemma's. Most of the "problems" we experience in life are merely challenges that encourage us to find a higher level of functioning and a better version of ourselves. You are the only expert in the room. I approach each new person I meet with a fair amount of humility and curiosity. We all have a story to tell and I am interested in each one I am priveleged to read.
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To say that he doesn't care because he has been away is a little rediculous if you ask me. He is in the military, probably working his ass off to support his family. We don't know why he chose military, just that he did. It's a very honorable job and EVERY American should be greatful he is out there serving all of us.
Ok here's my take on it..I personally don't agree with this war we are fighting. We are butting our noses in other country's business. I have respect for men of REAL wars..WW2 veterans, men from the civil war, men who fought for our freedom, not other country's freedom.
Probably will get bashed for that, but idc..war nowadays is not like it used to be. I've heard so many stories from military wives abut how thei husbands cheated on them while on tour, drink and party constantly, etc. So it's not all glory and star spangled banner war action, that I know.
OP it does sound like you're falling out of love with your DH. Ask him if he'lll do counseling? If he's not willing to work on the relationship then at least you tried.
Jen(24), married to Chris (22) on 8/5/11
Reached gold bottles!
Super Soggy working mom to CJ 11-26-11
What do you expect him to do on the weekends when everyone else goes out? I'm certainly not saying he has the right to turn into a raging alcoholic, but seriously, do you want him to sit home alone while everyone else goes out?
Sounds to me like you're looking for a way out of your marriage. Nothing wrong with that, but you need to be upfront about it.
The two of you need a chance to reconnect as a couple and he needs the chance to prove himself as a father. As such, I would go to Italy with these things in mind as well as a contingency plan for if/when you decide to leave him and Italy. Go, and work on your marriage; give him a chance to be a father.
But you need to mean business: he needs to know there are comsequences for his partying; he needs to be a father, and that doesn't include clubbing and gambling.Men respond to action, not words, so if he screws up just once, have a plane ticket ready and SHOW him it's not acceptable to act like a frat boy anymore.
Mama to ♥ Lily ♥ Nov. 2011
not saying that him going out and partying all the time would be ok if he was home with you and lo..but whether korea is a warzone or "frat party" is irrelevant..what else is he supposed to do? why sit at "home" and be sad and lonely and stay away from his friends while he is away from you? i know having a baby is hard work and when you are single its constant--but when you're mom comes to help you, and you get that "break" do you just sit and do nothing? i know when i get a "break" i take that loooong relaxing bath, see a friend i dont' normally see, things that like that. i know it seems weird to compare the two but its essentially the same thing i think. he can't be withyou helping right now whether he wants to or not..so i wouldpersonally see how things are--and actually give him a chance to see how good of a husband and father he is, cause he has no idea yet. 10 days isn't enough, and thats not his fault that thats all he could be there for. the point is, if you loved him, if you loved who he was, well you need to see if thats who he still is i guess, i think you owe him that much! just a chance, thats all. when you are together again, and he doesn't want to help with LO, wants to go out and party all the time and its not something he needs help quiting--like an addiction or something--he just doesn't then you will be able to see that he really has changed into something you don't want to be a part of anymore. like pp's said, we don't know the whole story really, but fromw what you've said, i think he deserves a chance to be a dad and show you that he is there for you.
Bluefireeyes: whether you agree with it or not, we are in war. Have a little respect, saying all men in military cheat and party is not a correct assumption. There are still great guys out there. They are people's husbands, dads, sons, uncles....
My husband, who has never cheated btw, is a sailor and I am damn proud of him and respect him and the other sailors for the sacrifices they make everyday for their families and our country.
OP, please go to community.babycenter.com/groups/a55... for support from other military spouses to help you with your situation.
I agree with pp that it sounds like you have already made your decision.
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16 Angel Crafts to Make: Homemade Christmas Ornaments & Decorations
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Wishing Star Canvas
By: DecoArt
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Create a dazzling decoration with wishful thinking. In Christmas colors, this sign works well as holiday decor, but the message is great all year round.
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Dazzling Metallics
- DA261 - Festive Green --- NEW!!
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- 2 1/4" wood star
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- 4" x 6" flat canvas
1. Refer to photo for color placement and let dry between steps.
2. Paint star Splendid Gold.
3. Basecoat canvas front Festive Green.
4. Use Festive Red and liner brush to write word "wish" on canvas front.
5. Glue star to canvas for dot over letter "i".
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Golf: FAIRWAY THE LAD; EXCLUSIVE Ferrie: It's Shearer First, Then Augusta
Byline: By SIMON BIRD
KEN FERRIE has warmed up for next month's US Masters by playing for a fiver against football stars like Alan Shearer and Shay Given and Olympic triple jump champion Jonathan Edwards.
The Geordie ace is a regular on the course with Edwards and Newcastle keepers Given and Steve Harper.
And he's completing his Augusta preparations with a challenge game against Shearer... but will be giving the strike legend a mean handicap following a couple of below par rounds.
The Ashington-born star, who came close to winning last year's US Open before finishing sixth, revealed that mixing with his new sporting mates has helped him overcome one big problem - doubting he really belonged in the company of Tiger Woods.
Ferrie, one of only a handful of Brits to qualify for Augusta, has spent the winter working on his swing in the North- East and has accompanied Newcastle on their UEFA Cup trips.
He said: "I love getting to know the Newcastle players and Jonathan Edwards. I play a lot of golf with them.
"Some of the players are very good. Harps is very good and Shearer is handy as well. They haven't taken any money off me yet, but it is only a matter of time.
"Shearer has shot four or five under, so I think we will be negotiating his handicap very closely. I don't want him taking any money off me."
The serious business starts this week at the Madeira Open before jetting to the US.
Ferrie, who made a flying visit to Augusta for some practice last week, added: "I qualified for the Masters by finishing sixth in the US Open. …


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text: I have recently install the beta version of Windows 8 on my computer and it is running properly without any issues. When I was searching for some games like Chess Titans in this operating system then I couldnt find it anywhere listed? Does this means that in Windows 8 we will not get this games preinstalled or are we supposed to download it from the microsoft website someplace? Thanks


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Idfu Transportation Tips by Kuznetsov_Sergey Top 5 Page for this destination
Idfu Transportation: 8 reviews and 28 photos
Most RecentBest Rated
- 1
Bridge across the Nile at Edfu
There is a bridge across the Nile in Edfu. I was nearly surprised how low it was! Though our boat wasn't very high with its 4 decks, when it was passing by the bridge a sailor had to incline the aerial that it had not touched the arches of the bridge.
Mode: TO
Type: Ship/Boat
Horse Carriages - Fiacres in Edfu
As the temple is on the distance of several kilometers from the bank of the Nile right after leaving boats tourists may see numerous horse carriages - fiacres. For the majority of tourists it appears a pleasant and unexpected surprise.
You will agree, that the trip by a fiacre is much more attractive, than a trip by a usual excursion bus. East color penetrates you literally during a trip and you become the accomplice of traffic in which besides you tens others horse and donkey carriages participate. The trip lasts about ten minutes - exactly so much to take pleasure and do not get tired.
You may see Egyptian fiacres in Edfu on my Edfu Fiacre 2,20 minute VIDEO CLIP from my YouTube channel .
Mode: TO
Type: Other
Edfu (Idfu) harbor
Cruise boats, which begin their way from Luxor to Aswan, usually make their first stop in Edfu early in the morning.
When we have moored to the bank at Edfu harbor, about ten moored boats already stood there. They are usually moored to each other. Therefore several chains of three - four boats in each were moored along the bank of the Nile. Last come boat becomes the last moored in a chain. Therefore passengers consistently pass by decks of 2-3 boats before to step on the bank. In process of returning tourists after the excursion to their boats, they leave the mooring. Therefore tourists get on the boat from the mooring at once while other boats still wait for the passengers.
Mode: TO
Type: Ship/Boat
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