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Please remember to follow the manual of style and code of conduct at all times.
Check BNN and Bulbanews for up-to-date Pokémon news and discuss it on the forums or in our IRC channel #bulbagarden on irc.systemnet.info.
Check BNN and Bulbanews for up-to-date Pokémon news and discuss it on the forums or in our IRC channel #bulbagarden on irc.systemnet.info.
Changes related to "User talk:Shinylucario"
From Bulbapedia, the community-driven Pokémon encyclopedia.
This is a list of changes made recently to pages linked from a specified page (or to members of a specified category). Pages on your watchlist are bold.
30 May 2016
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Interior Acoustical PanelsInterior Ceiling Panels
Tectum Ceiling Panels combine a unique textured beauty with superior abuse resistance. These high-impact wood fiber panels combine several functions that truly set them apart for use in commercial, institutional, recreational and industrial buildings. The panels are available in a wide range of sizes. They can be cut easily and shaped with standard woodworking tools, and installed in standard grid systems or direct attached. By using Lay-In, Tonico, Multiplane, V-line and Designer Series Tectum panels, the designer can create a variety of three-dimensional patterns.
Tectum decorative and acoustical panels can take repeated abuse and still retain their appearance. Tectum Ceiling Panels have remained the product of choice for over 50 years for any area where noise is a problem and the ceilings are subject to abuse.
NRC/Mountings - Noise Reduction
Up to 1.00 NRC can be achieved depending on mounting style. Furring strips installed horizontally (when using
vertical panels) are recommended and should be a maximum of 24" o.c. when using 1"-thick panels.
Installation Instructions
- I-11 Tectum Interior Ceiling Panel Installation Instructions (Coming Soon)
- Grid Ceiling Panel Detail (Keep Clip Detail)
- Grid Ceiling Panel Specifications
- Concealed Corridor Ceiling Panel Detail
- Concellico Ceiling Panels Details
- Corridor Spanning System Detail
- Designer Series Ceiling Panel Detail
- Designer Series Plus Ceiling Panel Detail
- Full Span Corridor Details
- Interior Panel Ceiling Screw Attach Detail
- Multiplane Ceiling Panel Detail
- Soft-Look Tonico Ceiling Panel Detail
- Tonico Ceiling Panels Detail
ASTM E-84 - Flame Spread/Smoke Developed
Tectum Interior Ceiling Panels - 0 Flame Spread, 0 Smoke Developed
Tectum Ceiling Panels are available in natural, painted white or custom colors. These panels may be painted or repainted in the field up to six times without reducing their acoustical properties. Tectum Ceiling Panels meet the requirements of ASTM E-1264 Type XIV pattern L Class A.
- 1" - 1.65 lbs./square foot
- 1½" - 2.55 lbs./square foot
- 2" - 3.50 lbs./square foot
- 1.75 per inch of thickness
Tectum ceiling and wall panel measurements are plus or minus
1/8 - 1/4". Thicknesses are nominal. Panels that are to be butted must be beveled and will require field fitting or molding can be used to cover edges.
Tectum Acoustical Panels can be used over swimming pools and in open construction such as breezeways and open garages. They should not be installed where they will come in direct contact with water or condensation. Reveal edge panels (Tonico) should not be used for this purpose.
1" panels should not be used where the relative humidity will exceed 85%. Panels 1½" or thicker are not restricted by humidity conditions.
In all cases, the plenum must provide cross-ventilation to prevent condensation.

subset: commoncrawl


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In this sequel (and prequel) to the bestselling DVD, The Ultimate Gift, daily pressures of running his late grandfather's foundation and being sued by his greedy family mount against Jason Stevens. Also affected is his relationship with his treasured Alexia, who is preparing to depart for a mission trip. After coming across a journal from his late grandfather, Red Stevens, Jason hopes the writings will guide him to live The Ultimate Life.
In The Ultimate Gift, Jason was tasked with completing assignments centered around 12 gifts before he was eligible for "the ultimate gift" from his late grandfather: gifts of work, money, friends, learning, problems, family, laughter, dreams, giving, gratitude, a day and love.


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Admission: Free
Meeting Place: Visitor Center
Rebekah the Reducer talks dirty about the three R's of waste-Reducing, Reusing, and Recyling! In celebration of America Recycles Day, learn some easy ways to reduce and reuse your trash! Let's let Arkansas "Shine" with a few everyday steps.
Explore Hobbs State Park-Conservation Area with our helpful maps and brochures! Just click on an icon to view, or right-click on your mouse to save a
copy to your computer.


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I reckon it would pay you to have a look at the official DCL site Jeff here.Originally Posted by Deafjeff, post: 226672
This will give you full details of all the cruises on offer and loads more info also.
If you can afford it though I would certainly go for a cruise with a minimum of 5 nights duration as it seems as though no sooner are you on the ship than it`s time to leave on the 3 & 4 day cruises.
My DW and I have only done one 3 day cruise, the remainder have been for 7 days or more.
I have always found that DCL respond very quickly to any email requests and you can book a cruise on line.
In addition you can talk to the DCL reps who have a desk at some of the WDW resorts. I dunno exactly which ones they are but there is definately one at the GF which is manned at certain times.
The most cost effective way though is to book your next cruise while on board the ship [if you become hooked on cruisin` that is!], as you get a 10% discount as well as on board credits etc..
Hope this helps but if you need any more info then just holler!


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Cam Elyaf has received the Germanisher Llyod certificate for wind
All News
Cam Elyaf Sanayii A.Ş.
Cam Elyaf San. A.Ş. is a part of ŞİŞECAM GROUP and our business scope covers the production FIBERGLASS for composites (GRP) industry.
We produce "E" glass fiber reinforced materials, please click here
Domestic and International sales network for
For information, please click here
Environmental and Quality Policy and Quality Assurances
click here
Please click here to receive recent information about our company


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Resources requests
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April 26th, 2010 (10:50 PM). Edited April 26th, 2010 by BlackWaltz3.
Join Date: Jul 2009
Gender: Male
Posts: 188
Can i have someone do a front and back battler sprite for me of the fakemon in the attachment? I don't mind if it is scratched, spliced, mutated or whatever. DO NOT do a shiny, it's not necessary. Just a few notes before you do it though:
It is a starter - don't make it too big or small.
It is a sheep - the green fleece however is rather short (unlike mareep's) and as such should not be fluffed up too much
The yellow thing on it's back is a flowerbud and the brown thing on it's head is kind of like a helmet/downed ears.
Also, the pic is an old image i made on inkscape, so it must be known that the toes are supposed to be like chikoritas.
The sprite need not be the same pose, by all means make it more...action-y.
Hopefully someone can help. All credit will be provided where it is due.
Also, magicbus, i have compiled a bunch of graphics into an outside tileset, credits are long and varied (and some belong to me) so if you want it pm me and give credit to all of the people involved.
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- Description
Product Quality
Image Accuracy
Fit Advice
Round 'Em Up Women's Sexy Sheriff CostumeWomen's sexy sheriff fancy dress costume, made by California Costumes. Shoot to thrill in this saucy women's Western costume - you'll put the wild in Wild West at your next Cowboys and Indians fancy dress costume party!
- Vest
- Duster coat
- Holster & belt
- Collar
- Hat
- 2 sheriff badges
- Black polyester duster style coat.
- Sleeveless waistcoat vest with faux suede front, mesh back, back ribbon ties and decorative silver buttons.
- Separate white collar with velcro fastening to the back and a decorative bolo tie.
- Black faux suede cowboy hat.
- Black imitation leather belt and attached holster.
- Two detachable, silver coloured plastic star shaped sheriff's badges.
Boots and pants not included.
- Size Chart
Small Medium Large X-Large Bust 86-92cm 91-97cm 97-102cm 102-107cm Waist 63-69cm 69-74cm 74-80cm 80-85cm Hip 90-95cm 95-100cm 100-105cm 105-110cm Size 8-10 10-12 12-14 14-16
Please note that costumes are tagged in USA Sizing, we have converted to Australian
- Reviews
Service 5 star :50% ( 1 ) 4 star :50% ( 1 ) Quality 4 star :100% ( 2 ) Delivery Speed 5 star :100% ( 2 )
2 Item(s)Excellent costume Review by Joy Varlet
Quality Service Delivery SpeedWas amazed at how quick delivery was Review by Colleen King Quality Service Delivery Speed
- Delivery
Orders placed before 3pm Adelaide time are guaranteed same day postage on business days Monday to Friday. Express post ( $12.95 per order or FREE for orders over $100) will be delivered in 1-3 business days within Australia depending on your location. To check if your postcode is within Australia Posts overnight delivery network click here. For information on International Shipping click here.
- Returns
Party cancelled? Wrong size? Costume made you look silly? If you're not 100% satisfied with your purchase you are more than welcome to return your items for a refund or exchange. Please note that some restrictions do apply. Please follow the instructions and complete the Returns Form which was sent with your order. To download a new Returns Form click here. To find out how to quickly get your order back to us and for our full no fuss returns policy click here.


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|» Products
|» Bucket
|» Stainless Steel Bucket
Stainless Steel Bucket
Stainless Steel Bucket
Product Code : BJP 34
Brand Name : B. J. PRODUCTS
Product Specification
Aided by modern techniques and innovative machinery, we are able to manufacture and supply Stainless Steel Bucket. Made of finest quality stainless steel that is considered to be one of the best, which is available in the market, these products have a flawless finish. With a sturdy construction, these products have the capacity to bear heavy loads. These products are generally used in marriages, temples and social gatherings for serving food. Stainless Steel Bucket can be availed from us in different shapes and sizes as per the needs of the clients.
Gala No. A-1, Harichand Textile Mill Compound, L.B.S. Marg, Vikhroli (W), Mumbai - 400079, Maharashtra, India
Mr. Jayanti Panchal (Proprietor)
Accepts only Domestic inquiries Send Inquiry


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Areas of Law
- Personal Injury
- Workers Compensation
Overall Client Rating4.9 out of 5.0Communication Ability5.0Responsiveness4.5Quality of Service5.0Value for Money5.0
No feedback is available.
- Recommended by 2 Client(s)
- Last reviewed on 04/22/11
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CPC Participates in The "Big 5 Show" in Dubai
Construction Products Holding Company (CPC) is participating in the Big 5 International Building and Construction Show, the largest Construction trade show in the Middle East, currently taking place in Dubai from the 22nd through the 25th of November. As a participant, samples of CPC's construction products in UAE will be showcased, and throughout the construction conference various seminars will be held to discuss topics related to construction projects. During this conference, Dr. Faysal Alaquil, Director of Business Development for CPC International will address the attendees on the importance of Human Capital, retaining staff, recruitment and human resources in construction companies.
Dr. Alaquil is a member of two committees at the Jeddah Chamber of Commerce and Industry, the Construction and Erection committee and the Human Resources committee as well as being the Chairman of the Consultancy committee at the College of Engineering / Effat University.
Top Headlines
- Al Bustan Centre and Residence extends special rates to participants of The Big 5 show
- Imdaad participates at The Big 5 under JAFZA umbrella to throw spotlight on its state-of-the-art FM services
- The Big 5 Show 2003
- Gulf Extrusions showcasing latest architectural application products at Big 5 Show 2010
- Construction Products Holding Company (CPC) is Awarded "Best Company in Industrial Building Materials"


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From Qt Wiki
English Українська Magyar
qmake is a tool that automates the genaration of Makefiles for projects (using Qt or not), i.e., acts as a build system tool. There is a whole section of the official Qt documentation dedicate to this tool. The idea behind this wiki page is to collect some material not present there yet and also tips & tricks that can be useful.
External References
- Undocumented qmake, by Paul John Floyd. Although a little old, there is interesting stuff there.
Pages in category "Tools::qmake"
The following 3 pages are in this category, out of 3 total.


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Video: Cleaning Tips to Help Prolong Your Home's Windows
Information Text:
Matt Swales, A Better View Window Cleaning "It's important to have your windows cleaned because windows left unclean for long periods windows are porous and mother nature the mineral from things flying around can absorb into the pores of the glass and stain it permanently or it could take costly extensive measures to get that staining out of glass. The environment that the house sits in has a lot to do with how often they may want them cleaned. If the house sits in a wooded area or near construction that is blowing dirt across on it may want their windows more cleaned more often than a homeowner whose in a more established neighborhood with not as many trees or forest near it. Cost are determined by an onsite estimate. We walk around the house determine how many upper and lower windows, how hard they are going to be to access maybe the second and even third floor windows on the house and then the actual type of window and how the framing of it is in a house all of those go into to determine what the final cost will be."
Angie Hicks, Angie's List founder: "When interviewing potential companies always ask about a guarantee. Many window washing companies will offer a money-back guarantee if you're not 100% happy. Some will even offer a rain guarantee – so if it rains within a certain amount of time after the windows have been cleaned, they'll clean them again."
Angie's List Tips:
- The type of cleaning solution and equipment you need varies according to the type of windows you have.
- Most homes should get a thorough window cleaning twice a year – ideally in the spring and fall.
- MONEY SAVING TIP: Clean the first floor windows yourself, leaving the second floor to a pro.
Add new comment
1. It's important that I find a good one
2. I'm not an expert enough to know myself who is a good one
3. The industry is full of advertisements and misinformation
4. I wish I knew what experiences other people have had
That's very difficult to answer without seeing the house. As one poster said, the prep is the most important part. On newer homes that don't have a lot of peeling paint, the prep can be very minimal even as low as a couple or a few hundred dollars for the prep labor.
On a 100 year old home with 12 coats of peeling paint on it, then the prep costs can be very high and can easily exceed 50% of the job's labor cost.
A 2100 sq ft two story home could easily cost $1000 just for the labor to prep for the paint job. That number could climb too. Throw in lots of caullking or window glazing, and you could be talking a couple or a few hundred dollars more for labor.
Painting that home with one coat of paint and a different color on the trim could run roughly $1000 or more just for labor. Add a second coat and that could cost close to another $1000 for labor.
For paint, you may need 20 gallons of paint. You can pay from $30-$70 for a gallon of good quality exterior paint. The manufacturer of the paint should be specified in any painting contract. Otherwise, the contractor could bid at a Sherwin-Williams $60 per gallon paint and then paint the house with $35 Valspar and pocket the difference. $25 dollars per gallon times 20 gallons? That's a pretty penny too.
That was the long answer to your question. The short answer is $2000 to $4000 and up, depending upon the amount of prep, the number of coats, the amount of trim, and the paint used.


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14 yr 14.3 Lipizzan gelding He is quiet, quiet, quiet (not super lazy, but more on the laid back/push ride type). Has been ridden by Ammies and older…SOLD
"Winston"Â� is a remarkably safe, trainable stallion who is not at all studish. He has natural talent for collection and the airs, and his gaits are smooth…SOLD


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i owned the previous copies like wild world and the game cube edition one as well. I was hoping to make new friends in this copy need help getting fruits and buying other items please help. Thank you.
Im New to animal crossing new leaf! i want FRIENDS
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text: Anybody please provide necessary suggestion about Skype online support. I have tried all options and searches I could but it made no difference. I would be glad if you all help me with your suggestions. Actually I require Support on line or live chat for Skype. Also let me know where is live chat. Thank you in advance.


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Available for purchase on CengageBrain.com
Available formats and resources for instructors
MCITP GUIDE TO MICROSOFT WINDOWS SERVER 2008, Server Administration (Exam 70-646) prepares the reader to administer networks using the Microsoft Windows Server 2008 operating system and to pass the MCITP 70-646 certification exam. Focusing on updates to the software and in-depth coverage of the administration aspects of Windows Server 2008, this book includes topics such as installing, configuring, managing and troubleshooting. In addition, the book includes fundamental coverage of topics from other MCTS certifications. This full-color book also features a series of activities and readings designed to engage readers and offer real-world operating system experiences to users at any level.
This eBook is provided in VitalSource format. It is accessible on and offline on Mac, PC, Android & iOS.
Teaching supplements and resources are also available as a companion to this title.
It's so much easier when there are resources available to help you teach.
Sampling is only provided to Australia, NZ & Pacific Island locations
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Home > News > Community
Sunday, 20 July 2014
Recognised for effort: Nurfiqah talking to a reporter at the programme in Kuching.
KUCHING: The number of reported telecommunication cable theft cases in the first half of this year has been reduced to half compared to that recorded in the same period last year.
According to Kuching police chief ACP Roslan Bek Ahmad, there were 12 reported cases involving the arrest of 16 suspects from January to July last year.
"In this year's corresponding period, however, we received six cases involving the arrest of five suspects. Although many of these thieves were 'smart' — stealing cables at remote areas so as to avoid being detected — we had our own strategy to take them down.
"We strive to reduce the number of cases down to zero," he told reporters at an appreciation event cum sahur (pre-dawn meal during Ramadan) programme hosted by Telekom Malaysia Bhd (TM) early yesterday to mark the end of an Ops Cantas beat the night before.
ACP Roslan lauded the incentive given by the national telecommunication group to police personnel who had successfully apprehended cable thieves. However he was also quick to remind his men that such move should be seen solely as an encouragement, nothing more.
"We should never depend on any reward when it comes to performing our duties. With or without incentives, we must strive to do our best."
Meanwhile TM Sarawak general manager Sarbini Hamdan said with help from police, it had helped the group reduce its cost, which was in millions of ringgit.
Noting that most of the cases here happened near and around Muara Tabuan, he said cable thefts had adversely affected its customers.
"What if someone needed to make an emergency call but couldn't just because the cable was stolen? It could have been a life-and-death sitation. The restoration process alone would take at least seven days; sometimes it might be delayed as the cables get stolen again after installation," he said.
At the function, Che Nurfiqah Che Othman from Bintawa station was the sole female recipient of the TM Sarawak incentive for her role, together with two fellow police personnel, in trumping a cable theft attempt in Bintawa
on March 4, where they managed to arrest one suspect.
Tags / Keywords:
Courts Crime
Telco cable theft
ACP Roslan
Gamblers turn to illegal bookies since gambling dens have been shut, says SAC
Suspected drug traffickers caught
Indigenous rights leader says family threatened
Teen among gang of thieves nabbed
Cleaner sentenced to jail for cheating and CBT
For a hopping great time where else but Kangaroo Island!
Astoria strikes a balance
A timely partnership
Profound stories behind pieces of art
Doping will be criminal offence in Russia
Copyright © 1995- Star Media Group Berhad (ROC 10894D)(Formerly known as Star Publications (Malaysia) Berhad)


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Prevalence of antiplatelet therapy in patients with diabetes
Miller, Shaun R
Littenberg, Benjamin
MacLean, Charles D
Cardiovascular Diabetology
To determine the prevalence of, and patient characteristics associated with, antiplatelet therapy in a cohort of primary care patients with Type 1 or Type2 diabetes.
Subjects participating in a randomized trial of a decision support system were interviewed at home and medication usage verified by a research assistant. Eligibility for antiplatelet therapy was determined by American Diabetes Association criteria and clinical contraindications. The association between antiplatelet use and patient characteristics was examined using bivariate and multivariate logistic regression.
The mean age of subjects was 64 years (range 31–93). The prevalence of antiplatelet use was 54% overall; 45% for subjects without known CVD vs. 78% for those with CVD; 46% for women vs. 63% for men; and 45% for younger subjects (age< 65) vs. 62% for senior citizens. After controlling for race/ethnicity, income, education, marital status, insurance status and prescription coverage, the following were associated with the use of antiplatelet therapy: presence of known CVD (OR 3.4 [2.2, 5.1]), male sex (OR 2.0 [1.4, 2.8]), and age > = 65 (OR 1.9 [1.3, 2.7]). The prevalence of antiplatelet therapy for younger women without CVD was 32.8% compared to a prevalence of 90.3% for older men with CVD.
Despite clinical practice guidelines recommending antiplatelet therapy for patients with diabetes, there are still many eligible patients not receiving this beneficial therapy, particularly patients under 65, women, and patients without known CVD. Effective methods to increase antiplatelet use should be considered at the national, community, practice and provider level.
Related Articles
Methylenetetrahydrofolate reductase polymorphism 677C>T is associated with peripheral arterial disease in type 2 diabetes
Pollex, Rebecca L
Mamakeesick, Mary
Zinman, Bernard
Harris, Stewart B
Hanley, Anthony JG
Hegele, Robert A
Cardiovascular Diabetology
Individuals with diabetes are twice as likely to develop peripheral arterial disease (PAD), the manifestation of extensive atherosclerosis throughout the lower extremities. One putative determinant of PAD is the 677C>T polymorphism in the gene encoding methylenetetrahydrofolate reductase (MTHFR), which has previously been found to associate with various diabetic complications including retinopathy, nephropathy, atherosclerosis and coronary heart disease. The objective of this study was to investigate a possible role for the MTHFR 677C>T gene polymorphism with PAD in subjects with type 2 diabetes from an isolated aboriginal Canadian population.
The 677C>T MTHFR gene polymorphism was genotyped in 138 subjects of Oji-Cree descent. Participants were selected from a community-wide survey that included PAD assessment by ankle-brachial index (ABI) measurement, and also intermittent claudication assessment by the Rose questionnaire.
MTHFR 677T allele carriers had an increased risk of PAD with an odds ratio of 3.54 (95% CI 1.01, 12.4), P = 0.049, after adjustment for age, sex, duration of diabetes, hypertension, current smoking habits, and use of insulin or oral treatment for diabetes. None of these additional co-variables was significantly associated with PAD. No association was found between MTHFR genotype and intermittent claudication.
The genetic influence of the MTHFR 677C>T genotype on diabetic PAD is modest, yet for the Oji-Cree it is a major risk factor in comparison to other traditional risk factors.
Related Articles
Distinct effects of glucose and glucosamine on vascular endothelial and smooth muscle cells: Evidence for a protective role for glucosamine in atherosclerosis
Duan, Wenlan
Paka, Latha
Pillarisetti, Sivaram
Cardiovascular Diabetology
Accelerated atherosclerosis is one of the major vascular complications of diabetes. Factors including hyperglycemia and hyperinsulinemia may contribute to accelerated vascular disease. Among the several mechanisms proposed to explain the link between hyperglycemia and vascular dysfunction is the hexosamine pathway, where glucose is converted to glucosamine. Although some animal experiments suggest that glucosamine may mediate insulin resistance, it is not clear whether glucosamine is the mediator of vascular complications associated with hyperglycemia. Several processes may contribute to diabetic atherosclerosis including decreased vascular heparin sulfate proteoglycans (HSPG), increased endothelial permeability and increased smooth muscle cell (SMC) proliferation. In this study, we determined the effects of glucose and glucosamine on endothelial cells and SMCs in vitro and on atherosclerosis in apoE null mice. Incubation of endothelial cells with glucosamine, but not glucose, significantly increased matrix HSPG (perlecan) containing heparin-like sequences. Increased HSPG in endothelial cells was associated with decreased protein transport across endothelial cell monolayers and decreased monocyte binding to subendothelial matrix. Glucose increased SMC proliferation, whereas glucosamine significantly inhibited SMC growth. The antiproliferative effect of glucosamine was mediated via induction of perlecan HSPG. We tested if glucosamine affects atherosclerosis development in apoE-null mice. Glucosamine significantly reduced the atherosclerotic lesion in aortic root. (P < 0.05) These data suggest that macrovascular disease associated with hyperglycemia is unlikely due to glucosamine. In fact, glucosamine by increasing HSPG showed atheroprotective effects.
Related Articles
Circadian rhythm of autonomic activity in non diabetic offsprings of type 2 diabetic patients
Fiorentini, A
Perciaccante, A
Paris, A
Serra, P
Tubani, L
Cardiovascular Diabetology
The aim of the present study was to evaluate, by heart rate variability (HRV) with 24-hours ECG Holter (HRV), the circadian autonomic activity in offspring of type 2 diabetic subjects and the relation with insulin-resistance. METHODS: 50 Caucasian offsprings of type 2 diabetic subjects were divided in two groups: insulin-resistant offsprings (IR) and non insulin-resistant offsprings (NIR). Autonomic nervous activity was studied by HRV. Time domain and spectral analysis (low frequency, LF, and high frequency, HF, provide markers of sympathetic and parasympathetic modulation when assessed in normalized units) were evaluated. RESULTS. Time domain showed a reduction of total SDNN in IR (p < 0.001) and NIR (p 0.047) versus controls. Spectral analysis showed a total and night LF higher in IR and NIR than in control group (all p < 0.001). CONCLUSION. In frequency domain, the analysis of sympathetic (LF) and parasympathetic (HF) component evidenced an association between the offspring of type 2 diabetic subjects and a sympathetic overactivity. A global reduction and alteration of circadian rhythm of autonomic activity are present in offspring of type 2 diabetic patients with and without insulin resistance. The data of our study suggested that an autonomic impairment is associated with the familiarity for type 2 diabetes independently to insulin resistance and that an impairment of autonomic system activity could precede the insulin resistance.
heart rate variability; circadian rhythm; insulin resistance
Related Articles
Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons
Tenenbaum, Alexander
Motro, Michael
Fisman, Enrique Z
Cardiovascular Diabetology
There are three peroxisome proliferator-activated receptors (PPARs) subtypes which are commonly designated PPAR alpha, PPAR gamma and PPAR beta/delta. PPAR alpha activation increases high density lipoprotein (HDL) cholesterol synthesis, stimulates "reverse" cholesterol transport and reduces triglycerides. PPAR gamma activation results in insulin sensitization and antidiabetic action. Until recently, the biological role of PPAR beta/delta remained unclear. However, treatment of obese animals by specific PPAR delta agonists results in normalization of metabolic parameters and reduction of adiposity. Combined treatments with PPAR gamma and alpha agonists may potentially improve insulin resistance and alleviate atherogenic dyslipidemia, whereas PPAR delta properties may prevent the development of overweight which typically accompanies "pure" PPAR gamma ligands. The new generation of dual-action PPARs – the glitazars, which target PPAR-gamma and PPAR-alpha (like muraglitazar and tesaglitazar) are on deck in late-stage clinical trials and may be effective in reducing cardiovascular risk, but their long-term clinical effects are still unknown. A number of glitazars have presented problems at a late stage of clinical trials because of serious side-effects (including ragaglitazar and farglitazar). The old and well known lipid-lowering fibric acid derivative bezafibrate is the first clinically tested pan – (alpha, beta/delta, gamma) PPAR activator. It is the only pan-PPAR activator with more than a quarter of a century of therapeutic experience with a good safety profile. Therefore, bezafibrate could be considered (indeed, as a "post hoc" understanding) as an "archetype" of a clinically tested pan-PPAR ligand. Bezafibrate leads to considerable raising of HDL cholesterol and reduces triglycerides, improves insulin sensitivity and reduces blood glucose level, significantly lowering the incidence of cardiovascular events and new diabetes in patients with features of metabolic syndrome. Clinical evidences obtained from bezafibrate-based studies strongly support the concept of pan-PPAR therapeutic approach to conditions which comprise the metabolic syndrome. However, from a biochemical point of view, bezafibrate is a PPAR ligand with a relatively low potency. More powerful new compounds with pan-PPAR activity and proven long-term safety should be highly effective in a clinical setting of patients with coexisting relevant lipid and glucose metabolism disorders.
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Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study: baseline characteristics and short-term effects of fenofibrate [ISRCTN64783481]
Cardiovascular Diabetology
The Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) Study is examining the effects of long-term fibrate therapy on coronary heart disease (CHD) event rates in patients with diabetes mellitus. This article describes the trial's run-in phase and patients' baseline characteristics.
Research design and methods
FIELD is a double-blind, placebo-controlled trial in 63 centres in 3 countries evaluating the effects of fenofibrate versus placebo on CHD morbidity and mortality in 9795 patients with type 2 diabetes mellitus. Patients were to have no indication for lipid-lowering therapy on randomization, but could start these or other drugs at any time after randomization. Follow-up in the study was to be for a median duration of not less than 5 years and until 500 major coronary events (fatal coronary heart disease plus nonfatal myocardial infarction) had occurred.
About 2100 patients (22%) had some manifestation of cardiovascular disease (CVD) at baseline and thus high risk status. Less than 25% of patients without CVD had a (UKPDS determined) calculated 5-year CHD risk of <5%, but nearly all had a 5-year stroke risk of <10%. Despite this, half of the cohort were obese (BMI > 30), most were men, two-thirds were aged over 60 years, and substantial proportions had NCEP ATP III features of the metabolic syndrome independent of their diabetes, including low HDL (60%), high blood pressure measurement or treatment for hypertension (84%), high waist measurement (68%), and raised triglycerides (52%).
After a 6-week run-in period before randomisation with all participants receiving 200 mg comicronized fenofibrate, there were declines in total and LDL cholesterol (10%) and triglycerides (26%) and an increase in HDL cholesterol (6.5%).
The study will show the effect of PPAR-alpha agonist action on CHD and other vascular outcomes in patients with type 2 diabetes including substantial numbers with low to moderate CVD risk but with the various components of the metabolic syndrome. The main results of the study will be reported in late 2005.
Related Articles
Endothelial cell injury by high glucose and heparanase is prevented by insulin, heparin and basic fibroblast growth factor
Han, Juying
Mandal, Anil K
Hiebert, Linda M
Cardiovascular Diabetology
Uncontrolled hyperglycemia is the main risk factor in the development of diabetic vascular complications. The endothelial cells are the first cells targeted by hyperglycemia. The mechanism of endothelial injury by high glucose is still poorly understood. Heparanase production, induced by hyperglycemia, and subsequent degradation of heparan sulfate may contribute to endothelial injury. Little is known about endothelial injury by heparanase and possible means of preventing this injury.
To determine if high glucose as well as heparanase cause endothelial cell injury and if insulin, heparin and bFGF protect cells from this injury.
Cultured porcine aortic endothelial cells were treated with high glucose (30 mM) and/or insulin (1 U/ml) and/or heparin (0.5 μg/ml) and /or basic fibroblast growth factor (bFGF) (1 ng/ml) for seven days. Cells were also treated with heparinase I (0.3 U/ml, the in vitro surrogate heparanase), plus insulin, heparin and bFGF for two days in serum free medium. Endothelial cell injury was evaluated by determining the number of live cells per culture and lactate dehydrogenase (LDH) release into medium expressed as percentage of control.
A significant decrease in live cell number and increase in LDH release was found in endothelial cells treated with high glucose or heparinase I. Insulin and/or heparin and/or bFGF prevented these changes and thus protected cells from injury by high glucose or heparinase I. The protective ability of heparin and bFGF alone or in combination was more evident in cells damaged with heparinase I than high glucose.
Endothelial cells injured by high glucose or heparinase I are protected by a combination of insulin, heparin and bFGF, although protection by heparin and/or bFGF was variable.
Related Articles
Hypertension control: results from the Diabetes Care Program of Nova Scotia registry and impact of changing clinical practice guidelines
Russell, Cory
Dunbar, Peggy
Salisbury, Sonia
Sketris, Ingrid
Kephart, George
Cardiovascular Diabetology
The objective of this study was to determine the rate of blood pressure control according to 4 sets of Canadian guidelines published over a decade in patients with diabetes mellitus attending Diabetes Centres in the province of Nova Scotia.
One hundred randomly selected charts from each of 13 Diabetes Centres audited between 1997 and 2001 were extracted from the Diabetes Care Program of Nova Scotia Registry. Multivariate logistic regression analyses examined the relationship between individual characteristics and self-reported antihypertensive use. Included were 1132 adults, mean age 63 years (48% male), with 9 years mean time since diagnosis of diabetes.
According to the 1992 guidelines, 63% of the patients and according to the 2003 guidelines, 84% of patients were above target blood pressure or receiving antihypertensive medications. Forty-seven percent of patients are considered to be hypertensive and not on treatment according to 2003 guidelines. The results of the multivariate analyses showed that the only factors independently associated with anti-hypertensive use was oral anti-hyperglycemic use.
Hypertension is an additional risk factor in those with diabetes mellitus for macrovascular and microvascular complications. The health and budgetary impacts of addressing the treatment gap need to be further explored.
Related Articles
Serum resistin is associated with C-reactive protein and LDL- cholesterol in type 2 diabetes and coronary artery disease in a Saudi population
Al-Daghri, N
Chetty, R
McTernan, PG
Al-Rubean, K
Al-Attas, O
Jones, AF
Kumar, S
Cardiovascular Diabetology
Resistin is an adipocyte-derived factor implicated in obesity-associated type 2 diabetes (T2DM). This study examines the association between human serum resistin, T2DM and coronary heart disease.
One hundred and fourteen Saudi Arabian patients (male: female ratio 46:68; age 51.4 (mean ± SD)11.7 years; median and range: 45.59 (11.7) years and BMI: 27.1 (mean ± SD) 8.1 Kgm2 median and range: 30.3 (6.3) were studied. Serum resistin and C-reactive protein (CRP), a marker of inflammation CRP levels, were measured in all subjects. (35 patients had type 2 diabetes mellitus (T2DM); 22 patients had coronary heart disease (CHD).
Serum resistin levels were 1.2-fold higher in type 2 diabetes and 1.3-fold higher in CHD than in controls (p = 0.01). In addition, CRP was significantly increased in both T2DM and CHD patients (p = 0.007 and p = 0.002 respectively). The use of regression analysis also determined that serum resistin correlated with CRP levels (p = 0.04, R2 0.045).
The findings from this study further implicate resistin as a circulating protein associated with T2DM and CHD. In addition this study also demonstrates an association between resistin and CRP, a marker of inflammation in type 2 diabetic patients.
type 2 diabetes; Coronary Artery disease; resistin; C-reactive protein
Related Articles
The central role of vascular extracellular matrix and basement membrane remodeling in metabolic syndrome and type 2 diabetes: the matrix preloaded
Hayden, Melvin R
Sowers, James R
Tyagi, Suresh C
Cardiovascular Diabetology
The vascular endothelial basement membrane and extra cellular matrix is a compilation of different macromolecules organized by physical entanglements, opposing ionic charges, chemical covalent bonding, and cross-linking into a biomechanically active polymer. These matrices provide a gel-like form and scaffolding structure with regional tensile strength provided by collagens, elasticity by elastins, adhesiveness by structural glycoproteins, compressibility by proteoglycans – hyaluronans, and communicability by a family of integrins, which exchanges information between cells and between cells and the extracellular matrix of vascular tissues.
Each component of the extracellular matrix and specifically the capillary basement membrane possesses unique structural properties and interactions with one another, which determine the separate and combined roles in the multiple diabetic complications or diabetic opathies.
Metabolic syndrome, prediabetes, type 2 diabetes mellitus, and their parallel companion (atheroscleropathy) are associated with multiple metabolic toxicities and chronic injurious stimuli. The adaptable quality of a matrix or form genetically preloaded with the necessary information to communicate and respond to an ever-changing environment, which supports the interstitium, capillary and arterial vessel wall is individually examined.
Atherosclerosis; Collagen; elastin; proteoglycan; structural glycoprotein; Integrin; oxidative stress; redox stress; MMP; TIMP; remodeling
Related Articles
Statins research unfinished saga: desirability versus feasibility
Fisman, Enrique Z
Adler, Yehuda
Tenenbaum, Alexander
Cardiovascular Diabetology
Drugs in the same class are generally thought to be therapeutically equivalent because of similar mechanisms of action (the so-called "class effect"). However, statins differ in multiple characteristics, including liver and renal metabolism, half-life, effects on several serum lipid components, bioavailability and potency. Some are fungal derivatives, and others are synthetic compounds. The percentage absorption of an oral dose, amount of protein binding, degree of renal excretion, hydrophilicity, and potency on a weight basis is variable. These differences may be even greater in diabetic patients, who may present diabetes-induced abnormalities in P450 isoforms and altered hepatic metabolic pathways. Thus, it is obvious that head-to-head comparisons between different statins are preferable than trial-to-trial comparisons. Such assessments are of utmost importance, especially in cases in which specific populations with a distinct lipid profile and altered metabolic pathways, like diabetics, are studied. It should be specially pinpointed that patients with metabolic syndrome and diabetes constitute also a special population regarding their atherogenic dyslipidemia, which is usually associated with low HDL-cholesterol, hypertriglyceridemia and predominance of small dense LDL-cholesterol. Therefore, these patients may benefit from fibrates or combined statin/fibrate treatment. This policy is not accomplished since in the real world things are more complex. Trials would require very large sample sizes and long-term follow-up to detect significant differences in myocardial infarction or death between two different statins. Moreover, the fact that new compounds are under several phases of research and development represents an additional drawback for performing the trials. Ideally, head-to-head trials regarding clinically important outcomes should be conducted for all drugs. Nonetheless, the desirability of performing such trials, which epitomize modern evidence-based medicine, is frequently superseded by the feasibility dictated by pragmatic and economic circumstances. In the latter case, in absence of solid systematic documentation of comparable health benefits and long-term safety, both researchers and practicing physicians should allude to the weight of scientific endorsement behind the arguments and seek for the possible strengths and weaknesses intrinsic to each specific study. In any case, conclusions based on surrogate endpoints cannot completely substitute head-to-head comparisons regarding patients' outcome.
coronary artery disease; diabetes; hyperlipidemia; statins; trials
Related Articles
Comparison of rosuvastatin and atorvastatin for lipid lowering in patients with type 2 diabetes mellitus: results from the URANUS study
Berne, Christian
Siewert-Delle, Annica
Cardiovascular Diabetology
The Use of Rosuvastatin versus Atorvastatin iN type 2 diabetes mellitUS (URANUS) study compared rosuvastatin with atorvastatin for the reduction of low-density lipoprotein cholesterol (LDL-C) in patients with type 2 diabetes.
After a 6-week dietary run-in, patients aged ≥ 18 years with type 2 diabetes and LDL-C ≥ 3.3 mmol/L were randomised to double-blind treatment with rosuvastatin 10 mg (n = 232) or atorvastatin 10 mg (n = 233) for 4 weeks. Doses were then titrated up to a maximum of rosuvastatin 40 mg or atorvastatin 80 mg over 12 weeks to achieve the 1998 European LDL-C goal (<3.0 mmol/L).
Rosuvastatin reduced LDL-C levels significantly more than atorvastatin during the fixed-dose and titration periods (p < 0.0001). Significantly more patients reached the 1998 LDL-C goal with rosuvastatin 10 mg compared with atorvastatin 10 mg at 4 weeks (81% vs 65%, p < 0.001). At 16 weeks, significantly more patients achieved their LDL-C goal with rosuvastatin compared with atorvastatin (94% vs 88%, p < 0.05) and more patients receiving rosuvastatin remained at their starting dose with reduced requirement for dose titration. At 4 weeks, 65% of rosuvastatin patients had reached their 2003 European LDL-C goal (< 2.5 mmol/L), compared with 33% of atorvastatin patients (p < 0.0001). Both treatments were similarly well tolerated with no unexpected safety concerns.
At the start dose and following dose titration, rosuvastatin was significantly more effective than atorvastatin at reducing LDL-C and achieving European LDL-C goals in patients with type 2 diabetes.
Related Articles
Metabolic effect of telmisartan and losartan in hypertensive patients with metabolic syndrome
Vitale, Cristiana
Mercuro, Giuseppe
Castiglioni, Carlotta
Cornoldi, Alessandra
Tulli, Arianna
Fini, Massimo
Volterrani, Maurizio
Rosano, Giuseppe MC
Cardiovascular Diabetology
Metabolic syndrome is a cluster of common cardiovascular risk factors that includes hypertension and insulin resistance. Hypertension and diabetes mellitus are frequent comorbidities and, like metabolic syndrome, increase the risk of cardiovascular events. Telmisartan, an antihypertensive agent with evidence of partial peroxisome proliferator-activated receptor activity-gamma (PPARγ) activity, may improve insulin sensitivity and lipid profile in patients with metabolic syndrome.
In a double-blind, parallel-group, randomized study, patients with World Health Organization criteria for metabolic syndrome received once-daily doses of telmisartan (80 mg, n = 20) or losartan (50 mg, n = 20) for 3 months. At baseline and end of treatment, fasting and postprandial plasma glucose, insulin sensitivity, glycosylated haemoglobin (HBA1c) and 24-hour mean systolic and diastolic blood pressures were determined.
Telmisartan, but not losartan, significantly (p < 0.05) reduced free plasma glucose, free plasma insulin, homeostasis model assessment of insulin resistance and HbAic. Following treatment, plasma glucose and insulin were reduced during the oral glucose tolerance test by telmisartan, but not by losartan. Telmisartan also significantly reduced 24-hour mean systolic blood pressure (p < 0.05) and diastolic blood pressure (p < 0.05) compared with losartan.
As well as providing superior 24-hour blood pressure control, telmisartan, unlike losartan, displayed insulin-sensitizing activity, which may be explained by its partial PPARγ activity.
angiotensin II receptor blockers; telmisartan; losartan; hypertension; metabolic syndrome
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Oxidative stress and the use of antioxidants in diabetes: Linking basic science to clinical practice
Johansen, Jeanette Schultz
Harris, Alex K
Rychly, David J
Ergul, Adviye
Cardiovascular Diabetology
Cardiovascular complications, characterized by endothelial dysfunction and accelerated atherosclerosis, are the leading cause of morbidity and mortality associated with diabetes. There is growing evidence that excess generation of highly reactive free radicals, largely due to hyperglycemia, causes oxidative stress, which further exacerbates the development and progression of diabetes and its complications. Overproduction and/or insufficient removal of these free radicals result in vascular dysfunction, damage to cellular proteins, membrane lipids and nucleic acids. Despite overwhelming evidence on the damaging consequences of oxidative stress and its role in experimental diabetes, large scale clinical trials with classic antioxidants failed to demonstrate any benefit for diabetic patients. As our understanding of the mechanisms of free radical generation evolves, it is becoming clear that rather than merely scavenging reactive radicals, a more comprehensive approach aimed at preventing the generation of these reactive species as well as scavenging may prove more beneficial. Therefore, new strategies with classic as well as new antioxidants should be implemented in the treatment of diabetes.
Antioxidants; Diabetes; Oxidative Stress
Related Articles
Vascular ossification – calcification in metabolic syndrome, type 2 diabetes mellitus, chronic kidney disease, and calciphylaxis – calcific uremic arteriolopathy: the emerging role of sodium thiosulfate
Hayden, Melvin R
Tyagi, Suresh C
Kolb, Lisa
Sowers, James R
Khanna, Ramesh
Cardiovascular Diabetology
Vascular calcification is associated with metabolic syndrome, diabetes, hypertension, atherosclerosis, chronic kidney disease, and end stage renal disease. Each of the above contributes to an accelerated and premature demise primarily due to cardiovascular disease. The above conditions are associated with multiple metabolic toxicities resulting in an increase in reactive oxygen species to the arterial vessel wall, which results in a response to injury wound healing (remodeling). The endothelium seems to be at the very center of these disease processes, acting as the first line of defense against these multiple metabolic toxicities and the first to encounter their damaging effects to the arterial vessel wall.
The pathobiomolecular mechanisms of vascular calcification are presented in order to provide the clinician – researcher a database of knowledge to assist in the clinical management of these high-risk patients and examine newer therapies. Calciphylaxis is associated with medial arteriolar vascular calcification and results in ischemic subcutaneous necrosis with vulnerable skin ulcerations and high mortality. Recently, this clinical syndrome (once thought to be rare) is presenting with increasing frequency. Consequently, newer therapeutic modalities need to be explored. Intravenous sodium thiosulfate is currently used as an antidote for the treatment of cyanide poisioning and prevention of toxicities of cisplatin cancer therapies. It is used as a food and medicinal preservative and topically used as an antifungal medication.
A discussion of sodium thiosulfate's dual role as a potent antioxidant and chelator of calcium is presented in order to better understand its role as an emerging novel therapy for the clinical syndrome of calciphylaxis and its complications.
atherosclerosis; atheroscleropathy; HDL-C; lipoproteins; osteoatheroitis; oxidative and redox stress; reactive oxygen species; end stage renal disease
Related Articles
Duration of streptozotocin-induced diabetes differentially affects p38-mitogen-activated protein kinase (MAPK) phosphorylation in renal and vascular dysfunction
Chen, Hongmei
Brahmbhatt, Sachin
Gupta, Akanksha
Sharma, Avadhesh C
Cardiovascular Diabetology
In the present study we tested the hypothesis that progression of streptozotocin (STZ)-induced diabetes (14-days to 28-days) would produce renal and vascular dysfunction that correlate with altered p38- mitogen-activated protein kinase (p38-MAPK) phosphorylation in kidneys and thoracic aorta.
Male Sprague Dawley rats (350–400 g) were randomized into three groups: sham (N = 6), 14-days diabetic (N = 6) and 28-days diabetic rats (N = 6). Diabetes was induced using a single tail vein injection of STZ (60 mg/kg, I.V.) on the first day. Rats were monitored for 28 days and food, water intake and plasma glucose levels were noted. At both 14-days and 28-days post diabetes blood samples were collected and kidney cortex, medulla and aorta were harvested from each rat.
The diabetic rats lost body weight at both 14-days (-10%) and 28-days (-13%) more significantly as compared to sham (+10%) group. Glucose levels were significantly elevated in the diabetic rats at both 14-days and 28-days post-STZ administration. Renal dysfunction as evidenced by renal hypertrophy, increased plasma creatinine concentration and reduced renal blood flow was observed in 14-days and 28-days diabetes. Vascular dysfunction as evidenced by decreased carotid blood flow was observed in 14-days and 28-days diabetes. We observed an up-regulation of inducible nitric oxide synthase (iNOS), prepro endothelin-1 (preproET-1) and phosphorylated p38-MAPK in thoracic aorta and kidney cortex but not in kidney medulla in 28-days diabetes group.
The study provides evidence that diabetes produces vascular and renal dysfunction with a profound effect on signaling mechanisms at later stage of diabetes.
NIDDM; thoracic aorta; kidney cortex; kidney medulla; blood flow; nitric oxide synthase; endothelin-1; signaling
Related Articles
Saturated free fatty acids and apoptosis in microvascular mesangial cells: palmitate activates pro-apoptotic signaling involving caspase 9 and mitochondrial release of endonuclease G
Mishra, Rangnath
Simonson, Michael S
Cardiovascular Diabetology
In type 2 diabetes, free fatty acids (FFA) accumulate in microvascular cells, but the phenotypic consequences of FFA accumulation in the microvasculature are incompletely understood. Here we investigated whether saturated FFA induce apoptosis in human microvascular mesangial cells and analyzed the signaling pathways involved.
Saturated and unsaturated FFA-albumin complexes were added to cultured human mesangial cells, after which the number of apoptotic cells were quantified and the signal transduction pathways involved were delineated.
The saturated FFA palmitate and stearate were apoptotic unlike equivalent concentrations of the unsaturated FFA oleate and linoleate. Palmitate-induced apoptosis was potentiated by etomoxir, an inhibitor of mitochondrial β-oxidation, but was prevented by an activator of AMP-kinase, which increases fatty acid β-oxidation. Palmitate stimulated an intrinsic pathway of pro-apoptotic signaling as evidenced by increased mitochondrial release of cytochrome-c and activation of caspase 9. A caspase 9-selective inhibitor blocked caspase 3 activation but incompletely blocked apoptosis in response to palmitate, suggesting an additional caspase 9-independent pathway. Palmitate stimulated mitochondrial release of endonuclease G by a caspase 9-independent mechanism, thereby implicating endonuclease G in caspase 9-indpendent regulation of apoptosis by saturated FFA. We also observed that the unsaturated FFA oleate and linoleate prevented palmitate-induced mitochondrial release of both cytochrome-c and endonuclease G, which resulted in complete protection from palmitate-induced apoptosis.
Taken together, these results demonstrate that palmitate stimulates apoptosis by evoking an intrinsic pathway of proapoptotic signaling and identify mitochondrial release of endonuclease G as a key step in proapoptotic signaling by saturated FFA and in the anti-apoptotic actions of unsaturated FFA.
free fatty acids; microvascular; apoptosis; caspase 9; lipotoxicity; mesangial cells
Related Articles
Isolated low high density lipoprotein-cholesterol (HDL-C): implications of global risk reduction. Case report and systematic scientific review
Hayden, Melvin R
Tyagi, Suresh C
Cardiovascular Diabetology
The importance of low high-density lipoprotein cholesterol (HDL-C), elevated non HDL-C (as part of the metabolic syndrome, prediabetes, and type 2 diabetes mellitus), and an isolated low HDL-C is rapidly emerging. The antiatherosclerotic roles of reverse cholesterol transport and the pleiotropic antioxidant – anti-inflammatory mechanistic effects of HDL-C are undergoing rapid exponential growth.
Case presentation
In 1997 a 53-year-old Caucasian male presented with a lipoprotein profile of many years duration with an isolated low HDL-C and uric acid levels in the upper quintile of normal. He developed an acute myocardial infarction involving the right coronary artery and had percutaneous transluminal coronary angioplasty with stenting of this lesion. He also demonstrated a non-critical non-flow limiting lesion of the proximal left anterior descending coronary artery at the time of this evaluation.
Following a program of global risk reduction this patient has done well over the past 7 years and remains free of any clinical signs and symptoms of atherosclerosis. His HDL-C and uric acid levels are currently in the normal physiological range.
Low HDL-C and isolated low HDL-C constitute an important risk factor for atherosclerosis. Therapies that lead to a return to normal physiologic range of HDL-C may result in the delay of atherosclerotic progression.
Apo A-1; ABCA1; Atheroscleropathy; Atherosclerosis; antioxidant; anti-inflammatory; lipoprotein A; redox stress; fibrates; niacin; ezetimibe; statins.
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House Sitting
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Arlana was warm, attentive, and flexible with her schedule. Definitely recommend!
Arlana came to stay with my Rat Terrier, Minnie and my two cats for a few days. Everyone was well taken care of and our apartment looked great when we got home. Thanks Arlana! We will definitely call on you again when the need arises.
Arlana was great. Oreo was very well cared for.
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Experienced house sitter who loves cats and dogs alike. If you're looking for someone responsible, loving, tidy and reliable I'm your gal.
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Medications, how well they get along with people and other dogs, etc
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As much or as little as you prefer based on my availability. I do have a full time job during the weekdays and will need to be out of the home from 8am-5:30pm. Other than that I have no issue being at your home or taking the dog/s for a walk 1-2 times per day and providing play and quality time.
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Nebraska's production by county is best represented by the map. The darkest areas produced the largest quantities in 2013. Historical numbers are in the following table. Totals can be viewed in the report Natural Gas Production.
Natural gas production has been falling since 2008, which was the year that natural gas production peaked at 3,083,488 thousand cubic feet and the price of natural gas began decreasing.
In 2013, Cheyenne County was the leader in natural gas production of all the counties with Chase County a close second. From 2008 to 2012, Chase County had been the leader .


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Making Love Sustainable is a project of Wendy Strgar, author of the books Love that Works and Sex that Works (forthcoming), a popular guest blogger on the topics of love, sexual health, and positivity, and an award-winning social entrepreneur. She is the founder and CEO of Good Clean Love, a national brand of organic personal lubricants and aphrodisiac products that are sold and endorsed by physicians nationwide for their safety. At Making Love Sustainable, we believe that relationships work when you focus on the love and positivity in your life. Need a reminder? Enter your email to get Wendy's insights on intimacy delivered every week.
Loving the Difficult (Mother)
A few weeks ago I started to feel a heaviness in my lungs that I was sure was pneumonia. I felt run down and my throat got irritated. I will be so sick in a few days, I thought, but then I wasn't. I felt fine again. My mom called to tell me she had pneumonia.I do …Read More
How we all perpetuate Rape Culture & what we can do to stop
In true late adopter fashion, I've finally jumped into watching "Game of Thrones" after, well, years of seeing headline after headline about the epic novel-turned-TV series. I got completely sucked in from the first episode. However, a curious thing happened while I w …Read More
"Let Happiness Search for You"
The title of this post is from an essay by Sparrow, a poet. I love this essay because I think it captures so well how important small, private moments of joy are to our ability to be human. In my experience, searching for big happiness brings more disappointment than pl …Read More
Anal Sex, Oral Sex, and Long-Term Relationships
I visited a friend for a night recently, and as usual we talked about sex. She told me that she and her boyfriend, with whom she has been with monogamously for about a year, started having anal sex after she brought up trying it -- she had accidentally seen a butt plu …Read More
What Do You Need to be Happy?
Maybe you think you need a vacation. Maybe you think you need certain kinds of food, or a certain amount of sleep, or certain clothes, or certain makeup, or certain books or friends or likes. Maybe you think you need a better cell phone or job or spouse in order to be h …Read More
The Importance of Female Friendship
This month, we celebrate both Women's History Month and International Women's Day. Both of these events have gotten me thinking an awful lot about the power of female friendship. Historically, amazing things have happened when women banded together in friendship to …Read More


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Watch out for turtles crossingMay 06,2013The Vermont Fish and Wildlife Department is reminding drivers that reptiles and amphibians are on the move this time of year.
The agency said amphibians migrate by the thousands each spring looking for breeding pools. They can frequently cross roads contributing to high rates of mortality among some species.
The Fish and Wildlife Department has been working to identify stretches of road where migrations take place and is working with the state Agency of Transportation to include culverts and wildlife barriers in road construction plans.
Most amphibian crossings take place on several rainy spring nights. Steve Parren, the departments wildlife diversity program director, said many frogs and salamanders are already well into their breeding season.
He said by late May turtles will start crossing roads to build nests in sandy embankments.MORE IN This Just InAnti-refugee activists are hosting a speaker at the Rutland Free Library tonight. Full StoryA Clarendon man pleaded innocent to his fourth DUI charge and a related charge in Rutland... Full StoryMan denies
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PHOTO: Kandi Burruss Buys Todd Tucker Big Budget Birthday Gift
Kandi Burruss spared no expense when it came to her husband's birthday.
She gifted Todd Tucker with a brand new Corvette over the weekend and proved she's not concerned with rumors her mother's suspicions that he's after her money.
Looks like the couple is enjoying married life now that the reality TV cameras have stopped rolling.
Perhaps Todd needs the new whip to get around Los Angeles as an executive producer of the upcoming series, "Hollywood Divas."
Check out his new ride:
Photo: Getty Images


text:
Iv seen that msg at the top of some plugin pages that says
This plugin hasn't been updated in over 2 years. It may no longer be maintained or supported and may have compatibility issues when used with more recent versions of WordPress.
I'm just wondering if some experienced WordPress developers could comment on this warning message and give us some general guidelines to follow.
Personally i tend to just simply avoid and not use a plugin that is not in active development and that doesn't have a decent number of reviews and downloads but i do have a few questions when i see this warning.
Sometimes i see this warning on a plugin but the support forum seems to be active and other places on the internet seem to be indicating that they use that plugin in tutorials and stuff.
Even if a plugin is fully updated it would be nice to know what experienced WordPress developers look for in a plugin when they decide to use a plugin instead of making one themselves.
I suppose what i really want to know is:
- Do out-dated plugins definitely pose a security risk?
- Is there a way to tell if a out-dated plugin has a security risk?
- besides compatibility issues, is there any reason or signs to look for that might make you decide not to use a plugin?
I know there is some inherent risk with Open Source software but Im interested in learning about and perhaps developing a guide to picking the best free and premium WordPress plugins.
My common sense tells me to steer clear of out dated and poorly rated plugins but I'd appreciate to hear some more specific advice/tips from the horses mouth so to speak, that i could use in writing a guide.


text:
JackalFights: Rin Nakai vs Danielle West
By Fightlinker on September 12, 2011
DJ ThunderElbows
Watching Rin lose the armbar over-and-over is really lame. I know some of it is fighting a bigger opponent who can offset her control of the upper body, but her opponent also hits like a girl.
Being adorable isn't enough for Rin to go anywhere.
Blackula Jonez
This was the first fight I ever seen of Rin's and it pretty much killed my interest in seeing her fight.
She has decent enough takedowns but if all you can do is go for the same failed arm bar why the fuck wouldn't you go for a different sub, like a choke or something.
If West had better striking and takedown defense (she actually was able to stuff/sprawl Rin would of gotten knocked the fuck out.
Back to the kitchen bitches!
you can't make a sandwich there!
DJ ThunderElbows
I gotta disagree Blackula – West punches like a girl. As a fan of WMMA it pains me to say that, but … yeah.


text:
Co-Op game partners list
Co-Op game partners list is what this is.
i wanna bang out the "cheevies" on this one aqap (as quickly as possible).
I am CDEagle147A add me as a friend and try to catch me online.
any one else wanna co-op through this ambitously cheap wooden startup company game?
add yor xbox user name below to do so. cus god knows no one who has the game knows any one in real life that also has it.
anyone else want to beat this one to death with the iron will of a hardcore gamer?
date and time! i'll play! :)
im gettin about one drop-in coop partner per-hour! the amount of peeps playin this one at any one time is very low and i think one of the reasons is cus its been divided into a US version an a Euro version.
so i have an american friend with the game and i compare on his acheevs list which says i Have 600 points on The Cursed Crusade he has -- , but he has 100 on The Cursed Crusade US and i have -- . f*******ing lovely.
Pleeeeeeeeez HELP us cursed crusaders finish this one . i want a get back to deadeyyyeland and my fellow gears! the generals need me!
Co-Op work
I was following the collectible guide till I got stuck on the loading screen of 4-2
I need someone who want to farm everything on the level.
Collectible count for both of us on Co-Op (: no matter who pick the item.
Also I read about the possibilities of doing the rest of the games co-op, if it happens I am ready to do the last 6 chapters in Co-Op.In one session if possible.
GamerTag: Mega Man X9 .
I will erase or Edit the post when done.
need to do 4.2 onwards message me on xbox live
If anyone needs cop-op help let me know, my game didnt glitch on level 4.2.
GT Cousin Jeffrey
Done thanks
Looking to tank this in co-op add me,
anyone looking to co-op this game? add me AzRAEL411
Looking to do chapters 4-2 onwards, finding all collectibles and also completing Nightmare mode for the 1000g ^^
Look me up, thanks!
GT: Darkyman2000
Im stuck at the loading screen for chapter 4-2. I have the US version BTW.
Add Me > EvilAndre
Will play nightmare as well
Looking to co-op weekends work best.
I'm looking for a partner to play nightmare chapter 4-2 with to get around the bug a lot of people are having with this chapter. Gamertage is
Ace Attorney 86
thanks in advance!
I too fell victim to the 4-2 glitch. Looking for someone to complete the game with.
I am looking for a partner to play 4-2 level and finish the game...
Please send me a msg first..
Gamertag: daissu
If anyone is still looking for someone, I just got this game. I would be ahppy to go through the whole thing with someone.
So much for beating this game in one night, got stuck at chapter 4-2 loading screen. I was following the collectible guide, any one interested in doing some co op this week and getting this done?
Gamtertag: Cossack William
need somebody to beat 4-2 with me and a friend were playing co-op and got stuck on 4-2.. we are going to each need to beat it looking to get all collectibles add me : Darkakri
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text:
Reading Room Blog
When New York Times reporter Bill Carter recently broke the story that NBC was planning on gently escorting Tonight Show host Jay Leno out the door for a younger, fresher face, it felt a little like déjà vu. That's because the same decision happened about ten years ago.
Carter's definitely the most qualified person to reveal such information. The news made me seek out his book, The Late Shift. The title is a breakthrough account of the shake-up at NBC after Johnny Carson surprisingly announced his plan to retire within a year. The network famously snubbed their Late Night host, David Letterman by hiring Leno, who had been a successful guest host for the legendary Carson.
I thought that Manhattan Projects was weird, and then the main characters stuck a cybernetic spike into Franklin Roosevelt's head, creating the world's first artificial intelligence.
Woe to anyone hoping that Jonathan Hickman's comic book series would be an accurate retelling of the construction of the atomic bomb. Sure, it gets mentioned from time to time.
The real driving force of Hickman's story, which ended up on many top comics lists last year, is the idea that the atomic bomb is just one of the hideous creations that super-geniuses Robert Oppenheimer, Albert Einstein, and Richard Feynman were working on. The other stuff... it ain't pretty.
What was it that defined the 1960s and made it one of the most important decades of the 20th century? This question is often asked, even by those who lived through its tumultuous events. Many classic novels portrayed and influenced the counterculture of the 1960s, including Hunter S. Thompson's Fear and Loathing in Las Vegas, J.D. Salinger's The Catcher in the Rye, and Ken Kesey's One Flew Over the Cuckoo's Nest. Another classic novel indelibly linked the culture of the 1960s was The Crying of Lot 49, one of Thomas Pynchon's earliest works. Supposedly the story of a woman seeking to sort out the estate of her dead boyfriend's will, The Crying of Lot 49 is a kaleidoscopic narrative that ventures through centuries-spanning conspiracies, bizarre characters, and an American rock band desperately pretending to be part of the British Invasion. One of Pynchon's earliest and shortest novels, The Crying of Lot 49 is a surreal whirlwind of 1960s literature.
Sailor Twain is a graphic novel that is heavy on the novel half of that term. The book draws from the romantic authors of the nineteenth century, from the sirens of the Odyssey, and from the emotional and carnal explorations of modernist literature.
On a riverboat churning through the Hudson, we meet two very different men. One is the serious, contemplative Captain Twain. The other is the more freewheeling boat owner Lafayette. They are about to become ravaged by the same obsession: mermaids.
"Powered by ideas, ideals, and by idealism." This is one of the first few lines in the mission statement of Project Gutenberg, a Web site stating that it is the first—and largest—single collection of free eBooks. Another tidbit worth mentioning is the fact that it is completely run by volunteers, and there are no dues or membership requirements. While they do gladly accept donations and new volunteers, the site makes its main goal clear: "...provide as many eBooks in as many formats as possible for the entire world to read in as many languages as possible."
Meets the second Monday of the month at 7:30 p.m. in the 3rd floor conference room
Current Selection:
Rediscover the timeless, treasured delights of the classics. Read, savor, and engage in lively discourse with our newest Book Group. Meets the 3rd Monday of every month, 7-8 p.m. For more information, please call the Adult Research Desk at 372-1144 ext. 232.
Current Selection:
Meets the first Thursday of the month at 7:30 pm.
Current Selection:
Join other readers to talk about books. The group meets the fourth Tuesday of the month from 7-9 pm.
Current Selection:
Meets the fourth Tuesday of the month at 7pm
Current Selection:


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text: Hello everyone! We are expecting baby #9 in Feb. 2014 :-) I had all vaginal births until baby #8 in April of 2012. I am wondering if anyone else been in my situation. I am considering a VBAC, and am being followed by two doctors. One doctor thinks I'm a good candidate for a VBAC...the other doesn't. I'm confused and unsure of what to do. I'm leaning more toward a repeat c-section because I am so scared of rupture, but the recovery from it last time was terrible. With many other children to take care of, I know an easier recovery from a vaginal birth would be better. Anyone who could offer advice would be very much appreciated! Thanks!


text:
Designed to create features such as metering holes, slots and diffusers, the FH series of six-axis, fast-hole EDM machines offer a full enclosure, 30" of X-axis travel and a tilt rotary table. The machines have a GE Fanuc 16Oi control and "Handyman" remote pendant in addition to a robotic tool changer, electrode dresser and pneumatic tool holder and stabilizers. The FH series machines also are available with the company's Micro-Pulse technology, which is said to virtually eliminate micro-cracking and recast associated with the EDM process that are particularly problematic for the aerospace and land-based power generation industries.
IMTS 2016 is right around the corner!
Now is the time to register for IMTS 2016, which runs September 12-17 in Chicago, Illinois. As the show approaches, please check our IMTS 2016 Zone for new product updates. We will also have information about new technology, pavilions to explore and conference information. In the meantime, check out IMTSTV for segments about the show and what's new in the world of manufacturing technology.
Learn More about IMTS


text:
Python Challenge Returns To South Florida In 2016South Florida's Burmese Python hunt will return after all.
Safety First As Divers Prepare For Start Of Lobster Mini-Season Lobster mini season kicks off Wednesday at 12:01 a.m. prompting local leaders to celebrate as well as authorities to remind the public of the rules.
Exclusive: Huge Python Captured At Shark Valley In Everglades National ParkA giant python captured at Shark Valley in Everglades National Park may be the second largest python ever caught in the State of Florida.
Top Spots To Go Star And Moon Gazing Near South FloridaWith or without a telescope, South Florida has plenty of ways to go stargazing. Join a local club or search out the stars on your own, either way you'll have an amazing experience that you can take with you anywhere.
Tropical, Everglades Parks Make Top 100 For Family FishingAh summer time, the kids are out of school, the weather is great and its time to hit the great outdoors.
Travel Guide To Florida's EvergladesHere's a practical guide for where to stay, where to dine and what to see in the Florida Everglades
Almost 3M People Visited South Florida's National Parks In 2014Almost three million people visited South Florida's national parks, generating over $231 million for the local economy last year, the National Park Service said.
President Designates Marjory Stoneman Douglas Home As Historic LandmarkDuring his visit to Everglades National Park Wednesday, President Barack Obama announced the Coconut Grove cottage of famed conservationist Marjory Stoneman Douglas would be designated as a national historic landmark.
Obama Uses Everglades As Backdrop To Warn Of Damage From Climate NeglectPresident Barack Obama, on Earth Day, put the national spotlight on the country's largest subtropical wilderness—the Everglades.
President Barack Obama To Travel To EvergladesPresident Barack Obama, on Earth Day, will use South Florida's iconic River of Grass as a backdrop to talk about climate change.
Study Suggests Pythons Throwing Off Everglades Food Chain A new study suggests the invasive Burmese Python is throwing off the balance of the food chain at Everglade's National Park.
Top National Parks Near South FloridaExplore America's natural wonders right in your backyard. Visit one of four South Florida national parks and travel north to central Florida to see how Florida does the wildlife, the everglades, history and water sports.


text:
Report: Bengals P Kevin Huber also suffered cracked vertebrae
Bengals punter Kevin Huber lasted just one quarter Sunday night after Steelers linebacker Terence Garvin's vicious helmet-to-chin block during a punt return fractured Huber's jaw. It gets worse: Huber also suffered a cracked veterbrae and is headed to injured reserve, according to ESPN's Chris Mortensen.
The injury came late on Antonio Brown's 67-yard punt return:
Turns out, Garvin's block is illegal, although no flag was thrown on the play.
According to the NFL rules, "It is a foul if a player initiates unnecessary contact against a player who is in a defenseless posture," and that includes "A kicker/punter during the kick or during the return." There's more: "Forcibly hitting the defenseless player's head or neck area with the helmet, facemask, forearm, or shoulder, even if the initial contact of the defender's helmet or facemask is lower than the passer's neck and regardless of whether the defensive player also uses his arms to tackle the defenseless player by encircling or grasping him" is prohibited.
Put another way: Garvin can almost certainly expect to be fined.


text:
Ana María Shua, or Ani, as she is known to her friends, exudes the aura of a
woman who is not afraid of her sensuality or of her maternal inclination.
She has deeply set dark eyes that convey her pragmatic nature. Her smile is
broad and engaging, her voice slow and rhythmical. When surrounded by
her daughters, she is playful. When immersed in her thoughts she becomes
somber, yet her dark side is curbed by her sense of humor and love of life.


text:
Knowing 2009 720p BRrip x264 aac vice(HDScene Release)
seeders: 0
leechers: 0
Added by vicerock18.14K in Movies > Highres Movies
Torrent verified. Downloaded 10 times.
Cast: Nicolas Cage, Matt Boesenberg, Rose Byrne, Terry Camilleri, Danielle Carter, Benita Collings, Janet Foye, Michael C. Gwynne, Karen Hadfield, Markus Hamilton and others
M.I.T. professor John Koestler links a mysterious list of numbers from a time capsule to past and future disasters and sets out to prevent the ultimate catastrophe.
Knowing 2009 720p BRrip x264 aac vice(HDScene Release) (Size: 1.62 GB)
Release Title: Knowing 2009 720p BRrip x264 aac vice(HDScene Release)
Encoded/Released by: Vice @ HDSceneRG
Encode date: UTC 2011-03-21 18:04:21
File size: Size (1.62GB Inclusive of Samples)
IMDB Link: http://www.imdb.com/title/tt0448011/
Storyline:In 1959 a young Lucinda Embry stands in her school's playground staring at the sun, hearing whispers. The school makes a time capsule to be opened fifty years later. Lucinda writes a page full of seemingly random numbers. Lucinda is later found in a closet, her hands bloody from scratching the numbers into the door. In 2009, Jonathan Koestler (Cage), a widower and professor of astrophysics at MIT, discusses life on other planets with his son Caleb. This leads to a discussion of where the boy's dead mother is. Caleb wears a hearing aid and knows sign language because he often hears confusing noises. Caleb attends the same school that Lucinda attended; when the time capsule is opened Caleb receives her page of numbers. He sees a mysterious stranger in the nearby trees and hears voices whispering. Jonathan finds the numbers, notices the sequence 911012996 and realizes it is a reference to the date and number of deaths from the September 11, 2001 attacks (9/11/01/2996). Jonathan finds similar information based on other numbers on Kevin's sheet. The last three dates on the page are in the immediate future. There are numbers between each of the dates that he cannot reconcile. Jonathan learns about Lucinda scratching at the door of the school closet, and that she recently died from a drug overdose. John's sister encourages him to reconcile with their father. Caleb receives more visits from mysterious strangers who give him a small smooth stone, and is shown images of the world on fire.
Genre: Drama | Mystery | Sci-Fi
Release date: 25 March 2009 (UK)
Nicolas Cage
Rose Byrne
Chandler Canterbury
Lara Robinson
Complete name: Knowing 2009 720p BRrip
Format: Matroska
File size: 1625.14 MiB
Duration: 2h 1mn
Overall bit rate: 1 870 Kbps
Container: AVC
Video Codec Type: x264 - core 114 r1913 5fd3dce
Average video bitrate:
Frame Rate: 23.976 fps
Encoding type: 2 Pass
Display Aspect Ratio: 2.35:1
Resolution: 1280x544
Source: Blu-ray
Audio Language: English
Audio Codec: AAC
Bitrate: %Audio_Bitrate%
Channel Count: 6 channels
Sample Rate: 48.0 KHz
GREETZ: To all my fellow HDScene Encoders, DarkScene, blackjesus and all other Releasers we respect....You know who you are.
Info Hash:2A697F7B4C3A53E190A3ACD4456274AA5AEDAB45
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Neophenom432 •
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audio: 10video: 10
Great copy, I only wish I knew a great program to change MKV files to MP4, most program mess up the audio.
jamestom229 •
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I like the idea behind this movie! This okay movie with Nick Cage.. Match Stick Men or Raising Arizona are to Cage movies I'd watch first...
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audio: 10video: 7
Stay away from this one. Quality on par with what I would expect from a 700mb rip, not a 1.6gb rip. Sharp edges with excessive compression artifacts and blurring on smooth surfaces. Video framerate says its 23.97fps but it's slightly choppy in motion sequences and looks like it's much less. Overall just a poorly done rip. Tested on VLC.
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text:
Michelle Stinson Ross has been scribbling and making up wild tales most of her life. For several years she worked at being a respectable adult, earning a Bachelors Degree in Business Communication. But as her three children got older, the drive to create came roaring back. An active blogger and social media addict, Michelle has been feverishly working on several story ideas. Her novella, Revenge of the Siren Song, is soon to be released. Her novel, Where Redemption Lies, will not be far behind.
Mrs. Ross currently resides somewhere near a sundrenched beach in South Florida where she soaks up inspiration with her husband and three daughters.
Location:Lone Grove, Oklahoma
Joined:Jul 17, 2010 10:36PM
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MichelleStinsonRoss Jul 30, 2010 01:23PM
@rachloves2write Can't ask for better than that.View all conversations
Featured work.
The Tale of Angus MacBain
By MichelleStinsonRoss
Social data: 280 reads. 3 votes. 9 comments.
Other Works by MichelleStinsonRoss.
Revenge of the Siren Song
Danger and adventure await in this tale from the Golden Age of Piracy. As deadly as she is beautiful, Ca...
Where Redemption Lies
352 3 8
When April Roberts discovers a mysterious wooden chest in her grandmother's attic, she has no idea that...


text:
"Keeweechic's Northampton / Hutt River Province" Northampton by keeweechic
Northampton Travel Guide: 51 reviews and 95 photos
Northampton is a lovely little historic town is just 52kms north of Geraldton. The town has actually been classified by the National Trust of Australia as a Historical Town. First settlers arrived in the area in the 1840's. The town was first known as Gwalla (after the area's copper mine) and the area was known as Mines Road District but this was all changed in 1871 to Northampton. The name was supposed to be in honour of John Stephen Hampton who was at the time, Governor of Western Australia and also the town, Northampton in England.
During the 1840's lead ore and copper were discovered and within the next thirty years some 4,000 tons of lead and copper were being produced annually.
The town lies in the Mid West region, an area known for its wonderful wildflowers. There is also evidence in cave paintings that Aboriginals also inhabited the area. Northampton was also part of the first government railway line in Western Australia which ran from Geraldton to Ajana and passed through the town.
Just 10kms north of Northampton is the independent sovereign state - Principality of Hutt River. This is really something very unique and the history of this principality being formed is fascinating. Well worth taking the time to pay Prince Leonard a visit and hear his story. Close by is also Horrocks Beach (22kms) which has an ideal beach for fishing, surfing, windsurfing and swimming.
Reviews (39)
Out the back of the memorabilia building is the 'tea rooms'. Certainly not much to look at and I don't think they were... more travel advice
This stone pier has a large piece of yellow ore on the top of it. This came from the mines in the Capricorn Range of... more travel advice
Feeling a need for energizing? You can take yourself inside the Kings Chamber of the 'Pyramid of Hutt'. This is a 5.3m... more travel advice
The chapel was designed by Prince Leonard and it has been used for investitures. The Prince also bestows knighthoods and... more travel advice
Comments (1)
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You are always welcome here at Audiko, where you may use the best ringtones for your iPhone. Today we have a ringtone of "紅" by X-Japan as well as 408 other ringtones by X-Japan. "紅" is a gorgeous track from the "BLUE BLOOD" album that was recorded and mixed by X-Japan at their studios together with other 18 tracks. You can listen to all 6 X-Japan – "紅" ringtone variations available here and download it for free right now. You can also explore other 11 albums produced by X-Japan for all time. "紅" is referred to J-Rock, and you may listen to a huge amount of J-Rock melodies absolutely for free. And finally, we have collected lyrics for this track and you can view it here as well. So feel free to browse, listen, download ringtones at Audiko.net. Make your phone sound cool!
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