text:
Blogs Home
with Tags: ibmsecurity X
- Sort by:
- Date ▼
- Title
- Likes/Votes
- Comments
- Visits
Storify: IBM Unveils Industry's First Intelligent Cloud Security Portfolio for Global Businesses
LAURA BRUCE firstname.lastname@example.com Tags: enterprise security softlayer iaas global cloud private public ibmcloud ibmsecurity analytics hybrid 1,489 Visits
[ View the story "IBM Unveils Industry's First Intelligent Cloud Security Portfolio for Global Businesses" on Storify ]
from Blog: IBM Cloud Analyst Insights
Top 7 Cloud Security Questions to Ask Community Blog
Marcel Santilli email@example.com Tags: cloud-security ibmsecurity cloud security 3,944 Visits
location.replace("http://securityintelligence.com/top-7-cloud-security-questions-to-ask/"); We've reached the point that most enterprises have moved past "If we deploy a Cloud," to "When we deploy a Cloud." Often...Modified by Marcel Santilli firstname.lastname@example.com
Top reasons why customers still bet their business on the mainframe Community Blog
Marcel Santilli firstname.lastname@example.com Tags: ibm-security cloud mainframe-security mainframe ibmsecurity mobile security business byod 7,140 Visits
This post is written by Anne Lescher , Product Marketing Manager with IBM Security Solutions. It seems like everyone is rushing to keep up with the latest IT innovations supporting our business operations. There is pressure to...Modified by Marcel Santilli email@example.com
A Zen Approach to Security Community Blog
Marcel Santilli email@example.com Tags: network-security security host ibmsecurity ibm_security virtual-environments network networksecurity vikash-abraham 3,969 Visits
Post by Vikash Abraham , Product Marketing Manager for IBM Security Solutions What Zen, Ancient Wisdom and Infrastructure Security Have in Common Ancient wisdom continues to amaze me, and this struck me: Isn't there a...Modified by Marcel Santilli firstname.lastname@example.com
Opportunity begets reality: The evolution of threats on the internet Community Blog
Bryan Casey firstname.lastname@example.com Tags: attacks cybersecurity security ibmsecurity cyber-security ibm-security 2,734 Visits
Today, there is a greater understanding of cyber security risks and challenges than ever before because it is hard to go even a single day without reading a story about an organization that has been breached. For many people the challenges around...Modified by Marcel Santilli firstname.lastname@example.com
Security is a multi-dimensional puzzle
Marcel Santilli firstname.lastname@example.com Tags: data impact2013 ibmimpact cto big-data ibm_security cloud ibm-security mobile-security social mobile-applications nataraj-nagaratnam security ibmsecurity ibm-impact 2 Comments 5,244 Visits
Post by Nataraj Nagaratnam ( @n_nataraj ) We are all witnessing how technology impact business, and how this is shaping up the future of enterprise IT. Current and emerging technologies - mobile, cloud, big data, social - help businesses...
from Blog: Middleware Conversations
Infosecurity Europe 2013: Day 3 Thoughts Community Blog
Marcel Santilli email@example.com Tags: ibmsecurity guardium risk security-intelligence infosececurity infosecurity-uk incident-response securie-coding auditing security qradar siem infosecurity-europe san security-requirements ibm_security infosec13 ips risk-assessment mainframe ibm-security infosec database-security 3,460 Visits
As the third day came to a close on Infosecurity Europe and our stand is now slowly being taken down, I wanted to provide some key highlights of the whiteboarding sessions that happened live on our interactive graffiti wall. How...Modified by Marcel Santilli firstname.lastname@example.com
Infosecurity Europe 2013: Day 2 Thoughts Community Blog
Marcel Santilli email@example.com Tags: infosecurity security infosec ibm_security tom-kendall mobile-security security-intelligence infosec13 europe ibm-security qradar ibmsecurity 2,711 Visits
IBM Security Systems had another great day at Infosecurity Europe, with good attendance at our stand for the hourly interactive graffiti whiteboarding sessions, which covered all the hottest security topics. In our workshops we had...Modified by Marcel Santilli email@example.com
Infosecurity Europe 2013: Day 1 Thoughts Community Blog
Marcel Santilli firstname.lastname@example.com Tags: ibm-x-force xforce infosec13 ibm_security x-force infosec ibmxforce europe tom-kendall ibmsecurity ibm-security big-data infosecurity-europe security infosecurity security-intelligence vulnerabilities byod 3,168 Visits
Wow, the end of a great first day at Infosecurity Europe . Our stand was very bright and impactful and with our industry experts, business partners and action packed agenda, it has been truly engaging day! We had four workshops...Modified by Marcel Santilli firstname.lastname@example.com
Security at IBM Impact 2013
Marcel Santilli email@example.com Tags: ibmimpact ibmsecurity impact2013 ibm-impact security ibm-security 4,104 Visits
Did you know IBM Security offers one of the world's broadest, most advanced and integrated enterprise security product and service portfolios? IBM Security's portfolio, supported by world-renowned IBM X-Force research and...
from Blog: Middleware ConversationsModified by Marcel Santilli firstname.lastname@example.com
Is your application security scanner smarter than a 5th grader? Community Blog
Bryan Casey firstname.lastname@example.com Tags: report x-force security trend xss application ibm 2012 vulnerability appsec ibmsecurity xforce 8,143 Visits
XSS vulnerabilities and security technology that thinks more like you Learning about the world around us and then modifying our opinions and actions as we learn more is a skill that we aspire to teach in every classroom, and it is a process...
New report analyzes and explores latest security threats and trends Community Blog
Marcel Santilli email@example.com Tags: attackers ibm_security hackers data ibm java ibm_mobile ibm-security vulnerabilities xforce ibmxforce x-force report research ibm-mobile ibmmobile ddos ibm-xforce security information-security mobile security-intelligence it ibmsecurity 7,401 Visits
NEW! IBM X-Force 2012 Annual Trend and Risk Report Twice a year since the late 1990s, IBM's X-Force Research and Development team releases a trend and risk report including content collected from dozens of thought leaders across the company. Its...
You may have 'Big Data' and not know it… can you protect it? Community Blog
Marcel Santilli firstname.lastname@example.com Tags: security-intelligence ibmsecurity ibm_security protect ibm-security big-data bigdata security data 7,510 Visits
You may have 'Big Data' and not know it… can you protect it? To many security executives the word "Big Data" seems to being something that someone else has and thus not applicable to ones own enterprise. Many Security managers assume...
Top 3 Basic Considerations to Secure the Cloud Community Blog
Marcel Santilli firstname.lastname@example.com Tags: endpoint-management host-security security security-intelligence data-security vikash-abraham ibm-security data endpoint ibmsecurity cloud-security cloud 13,766 Visits
Post by Vikash Abraham , Product Marketing Manager for IBM Security Solutions While Cloud has been clearly identified as the next step to IT optimization, essential for increased performance and cost reduction, many of us are in a haze when it...Modified by Marcel Santilli email@example.com
"Big Data" - The 2012 Word of the Year Community Blog
Melissa Stevens firstname.lastname@example.com Tags: data-security ibm-security ibmsecurity big-data security 5,362 Visits
This post is contributed by Kim Madia, World Wide Product Marketing Manager for Infosphere. Working at IBM, I have been fortunate enough to be a part of launching big data platforms to clients. Big data is more than simply a matter of size; it is an...
Cloud Security Tips for Small and Mid-sized Organizations Community Blog
Melissa Stevens email@example.com Tags: cloud-security security ibmsecurity 3,537 Visits
This post is courtesy of Ronnie Shelley, IAM Segment Manager for IBM Security. Organizations of all sizes are facing the same dilemma today. The online tools and applications you use to open up communications with customers, enable a mobile workforce, and...
IBM Intrusion Prevention Solutions Lead in Recent Third-party Testing Community Blog
Melissa Stevens firstname.lastname@example.com Tags: vulnerability tolly ibmsecurity ips exploits gx7800 intrusion-prevention 4,894 Visits
This post was contributed by Brian Fitch, Product Manager for Network Protection. The Tolly Group has just released a security efficacy report on the IBM Security Network IPS GX7800. The GX7800 was compared to open source SNORT version 188.8.131.52 and the...
Bigger Information Protection on System z - Extending privacy, audit and compliance for big data initiatives Community Blog
Melissa Stevens email@example.com Tags: ibmsecurity system-z big-data data-security privacy compliance 4,067 Visits
This post is courtesy of Mark Simmonds, Product Marketing for Data Governance and System z . Previously I talked about the security of information and highlighted some of the capabilities among others of the InfoSphere Guardium solution for the System z...
Taking the Rocket Science out of Data Encryption Community Blog
Melissa Stevens firstname.lastname@example.com Tags: data-security encryption ibmsecurity data security 5,343 Visits
This post was written by Anne Lescher, Product Marketing Manager with IBM Security Solutions. One of the biggest challenges is protecting sensitive information, and one of the biggest fears is losing that information to hackers. Who has not worried...
Leveraging the mainframe for cloud computing and consolidated security management Community Blog
Melissa Stevens email@example.com Tags: ibmsecurity cloud-security zsecure security data-security 8,964 Visits
This post is contributed by Glinda Cummings, WW Senior IBM Security Solutions Product Manager for zSecure Remember the good old days when we did our work from a dumb terminal, or worked remotely on the mainframe? Then came the personal...


text:
Crowd behavior: The night Kelvin Sampson took the microphone
I wrote about boorish crowd behavior for the Wednesday Oklahoman. You can read that column here. But I didn't reference a memorable game from 17 years ago when then-OU basketball coach Kelvin Sampson tried to change the culture a little at Lloyd Noble Center.
On Feb. 1, 1997, with the Sooners hosting Texas, the OU crowd repeatedly chanted "Texas sucks." And the crowd in unison laughed when referee Larry Ware tripped over an OU player and into a press table.
Sampson took the public-address microphone and said, "We're not going to stoop down and laugh at people. . . . Let's not say 'Texas sucks' anymore, either."
Sampson drew some criticism from OU fans. OU fans, like most fans, don't like being told what to do. To this day, some Sooner fans boo the pre-game football announcement from president David Boren, asking fans to treat the visitors and opponents with respect.
But it was a quality gesture by Sampson then and in short supply now. The lack of civility in sporting venues is a major problem. I would not take my granddaughters to a men's college basketball game. No way.
Seventeen years ago, after his request to the Lloyd Noble crowd, Sampson told the media, "Let's spend our energy making our team better … You can have a great program, an intense, hard-fighting, scrappy team and still be class, and that's what we want."
You can read my column on Sampson's act here.

subset: commoncrawl


text:
Aleksandar Bojinov was one of Bulgaria's pioneering cartoonists and comic artists. He has lived and worked in Miunhen. He made many cheerful pictures with verse, in the same fasion as 'Max und Moritz'. Among his works are 'Bulgaran' (1904) and the comic-like book 'Azbuka za Malkite' ('Alphabet for Children').
Artwork © 1968 Aleksandar Bojinov
Website © 1994-2016 Lambiek
Laatste update: 2009-07-24
Series en boeken door Aleksandar Bojinov op voorraad in de Lambiek Webshop:
If you want to help us continue and improve our ever- expanding database, we would appreciate your donation through Paypal.


text:
Go to: Sanjjanaa Galrani Home
Use keys to navigate
Sanjjanaa Galrani
Sanjana, is an Indian model and film actress, born and brought up in Bangalore. Though she appeared in quite a few Kannada films, it was the 2008 Telugu film Bujjigadu that brought her to limelight.
Related News
Go to : Wallpapers
Go to : Videos
Box office
Go to: Box office
- X-Men: Apocalypse (E26.06 * Cr
Sarbjit22.09 * Cr
Azhar29.70 * Cr
Buddha In A Traffic0.23 * Cr
Dear Dad0.13 * Cr


text:
A Camas resident said Tuesday, March 27, he will run for the Board of Clark County Commissioners.
Political newcomer Roman Battan, 31, said he will file as a Democrat against Commissioner Marc Boldt, 57, a Hockinson Republican seeking his third term.
David Madore of Vancouver, 60, and a Republican and CEO of U.S. Digital, has also said he'll run for the District 2 seat.
Filing week is May 14-18.
The top-two finishers, regardless of political affiliation, in the Aug. 7 primary will advance to the Nov. 6 general election.
In the primary, the candidates run districtwide. The general election is countywide.
Battan, a graduate of Camas High School and Clark College who has a bachelor's degree in business administration from Washington State University Vancouver, said Tuesday that he's always loved politics but hasn't been directly involved other than voting.
He has been involved with Watershed Stewards, a program of WSU Clark County Extension and the Clark County Clean Water Program. The program trains volunteers on ways to improve watersheds, and Battan has listened to presentations from county employees on environmental challenges such as polluted runoff.
In December, he was laid off from his job as director of sales at Vancouver's Capstone Technology.
Battan said the timing feels right to shift his focus from the private sector to public policymaking.
He said his campaign will focus on government efficiency, transparency and accountability.
"My vision of government is to have everybody feel like you can talk to your county representatives," he said.
And to raise his profile, he plans to do plenty of talking to voters.
"I have four pairs of tennis shoes I plan to wear out between now and August," he said.
He supports the most polarizing issue, the Columbia River Crossing, as a golden opportunity to improve infrastructure and make the county more desirable to employers.
Prior to working for Capstone, Battan paid his way through college by working for Wells Fargo.
District 2 covers east county, including parts of Vancouver east of Interstate 205.
In District 1, Democrats Ron Barca and Joe Tanner are running for the seat held by Commissioner Tom Mielke, a Republican seeking his second term.
District lines were recently redrawn following the release of the 2010 U.S. Census figures. District 1 covers north county and District 3 covers Vancouver and parts of Hazel Dell.
Each district has approximately 142,000 people.
Commissioner Steve Stuart, a Democrat who represents District 3, was re-elected in 2010.
Commissioners serve four-year terms. They currently earn $102,228 a year.


text:
May 28, 2016
Police visited 519 Avon Street in Lansing yesterday to check on the welfare of the two little girls inside, thanks to a tip from a concerned family member.
The parents were not home. Police will only tell us the girls were in the care of another person. The baby girl, seven months old, was dead. Her four-year-old sister was visibly in need of medical care.
Police say they aren't searching for suspects, but are simply waiting for autopsy results to understand how this all came to be. The medical examiner wasn't able to get a conclusive answer with an autopsy Wednesday.
Click Here to access the online Public Inspection File
Viewers with disabilities can get assistance accessing this station's FCC Public Inspection File by contacting the station with the information listed below. Questions or concerns relating to the accessibility of the FCC's online public file system should be directed to the FCC at 888-225-5322, 888-835-5322 (TTY), or firstname.lastname@example.com.


text:
desertification Companies in Texas
United Nations Convention to Combat Desertification (UNCCD)
based in Bonn, GERMANY
The international community has long recognized that desertification is a major economic, social and environmental problem of concern to many countries in all regions of the world.In December 1992, the General Assembly adopted resolution 47/188 which called for the creation of an Intergovernmental Negotiating Committee (INCD) to prepare, by June 1994, a Convention to ...
Society for Ecological Restoration
based in Washington, DISTRICT OF COLUMBIA (USA)
The Society for Ecological Restoration (SER) is a non-profit organization comprised of individuals and partner organizations from around the world who are actively engaged in the repair and recovery of degraded ecosystems utilizing a broad array of experiences, knowledge sets, and cultural perspectives. SER members include scientists, planners, administrators, ...
World Resources Institute WRI
based in Washington, DISTRICT OF COLUMBIA (USA)
World Resources Institute is an independent nonprofit organization with a staff of more than 100 scientists, economists, policy experts, business analysts, statistical analysts, mapmakers, and communicators working to protect the Earth and improve people`s lives. World Resources Institute (WRI) is an environmental think tank that goes beyond research to find practical ...
Renewable Carbon Management LLC
based in St. Cloud, MINNESOTA (USA)
Renewable Carbon Management, LLC (RCM) sells and licenses the NaturTech Composting System for converting organic materials into value added commodities. We also provide strategic partnerships and operating expertise for the lowest cost and highest environmental performance available.
European Inter-University Centre for Human Rights
based in 30126 Venice - Lido, ITALY
The European Inter-University Centre for Human Rights and Democratisation (EIUC) is an interdisciplinary centre of excellence formed by 41 universities from all European Union Member States. It was founded in 2002 on a commitment to the realisation of the values promoted by the EU, the promotion of high-level inter-disciplinary human rights education, research, training ...
Green Power Conferences
based in London, UNITED KINGDOM
Established in 2003, Green Power Conferences was the first to offer professionally organised events focusing on the sustainability sector. Over the last six years, we have welcomed over 13000 delegates from 138 countries and built a global database of 500,000+ contacts. Our expertise lies in producing high quality, interactive conferences that provide ample networking ...
based in Washington, D.C., DISTRICT OF COLUMBIA (USA)
The United States has a long history of extending a helping hand to those people overseas struggling to make a better life, recover from a disaster or striving to live in a free and democratic country. It is this caring that stands as a hallmark of the United States around the world -- and shows the world our true character as a nation. U.S. foreign assistance has always ...
Airius Europe Ltd
based in Ferndown, UNITED KINGDOM
Airius Europe Ltd are specialists in reducing energy by focusing on the process known as thermal destratification through the use of our patented thermal destratification ceiling fans. The Airius destratification method offers substantial annual energy savings on both heating and cooling costs by maximising the performance of existing HVAC equipment.
Bioenergy Crops Ltd.
based in Middlesex, UNITED KINGDOM
As energy crops expand and are being considered as feedstock for new power energy plants, many private organizations and experts are focused just on specific solutions and crops for local conditions they know. It is very difficult today to select an organization with a wider perspective, providing advice and consultancy services independently without looking forward to ...
based in WASHINGTON (USA)
Air to Water Harvest (A2WH) system uses a desiccant to absorb moisture from the air. The higher the humidity the more water our desiccant can absorb per pass which increases production. We use solar heat to drive both the airflow for the absorption process and to provide heat during the regeneration process which extracts the moisture from the desiccant and allows us to ...
Need help finding the right suppliers?
Let the XPRTs do the work for you


text:
Sometimes it is necessary to be able to refer to subexpressions of an equation. In order to do that these subexpressions should be numbered. In standard LaTeX there is no provision for this. To solve this problem Stephen Gildea once wrote subeqn.sty for LaTeX 2.09; Donald Arsenau rewrote the macros and Johannes Braams made them available for LaTeX2e.
Note that this package is not compatible with the package subeqnarray (written by Johannes Braams), but it can be used together with the LaTeX class options leqno and fleqn.
See also subeqnarray.
The authors are Donald Arseneau and Johannes L. Braams.
License: lppl Version: 2.0b Catalogued: 2015-08-03
- Visit
- Download
- Documentation
- Distributions


text:
Redirected from Dragon glass
this wiki
- "The Maesters call it 'obsidian'."
- ―Samwell Tarly
Dragonglass is a common name in Westeros for the substance known as obsidian, a form of volcanic glass. Along with Valyrian steel, it is one of the two known substances capable of killing White Walkers. It is also responsible for transforming men into White Walkers, first performed during the Dawn Age.
Large amounts of dragonglass can be found on Dragonstone.[1]
Season 1Edit
Doreah tells Viserys she's seen a man from Asshai with a dagger of real dragonglass.[2]
Season 2Edit
Grenn, Edd, and Samwell Tarly find a cache of dragonglass spear heads along with an old warhorn buried in the snow on the Fist of the First Men. Sam identifies the material, but is unsure why it would have been left on the Fist by a ranger of the Night's Watch. Edd suggests that whoever it was, they wanted someone else to find the weapons.[3]
Season 3Edit
After escaping Craster's Keep with Gilly, Sam shows her a piece of the dragonglass he had found. She asks what it does, and Sam responds that he isn't sure it does anything. He does remark how beautiful it is however.[4] Sam later uses his dagger to slay a White Walker that was after Gilly's baby. When Sam stabs the White Walker in the shoulder, the creature turns to ice and shatters.[5] Sam provides Bran Stark with a dragonglass dagger and Meera Reed with a set of dragonglass arrowheads for their journey beyond the wall. [6]
Season 5 Edit
Stannis tells Sam that there is dragonglass on Dragonstone. [7]
At Hardhome, Jon Snow gives Sam's dragonglass to the Free Folk he is trying to convince to come South of the Wall with him, telling them Sam's experience of killing a White Walker with dragonglass. Some of the wildlings are convinced, partly due to the dragonglass. Later, during the evacuation, the Night's Watch oversees the collection of dragonglass needed for the defense of the Wall. However when the White Walkers and the horde of wights attacked most of the dragonglass is left behind when they overrun the whole settlement.[8]Wun-wun, a giant at Hardhome who survived the invasion may have kept a dragonglass arrowhead he was examining as the attack began.
Season 6 Edit
Dragonglass is revealed to be the substance that turns men into White Walkers. The first White Walker was created when Leaf and several other Children of the Forest forced a dragonglass dagger through a First Man's heart. When the White Walkers invade the Cave of the three-eyed raven, one of the Children tries to kill a White Walker with a dragonglass spear, but the blade is blocked by his chest armor and he kills her. Meera Reed then kills him by throwing another dragonglass spear into his unprotected neck. [9]
Image GalleryEdit
In the booksEdit
In the A Song of Ice and Fire novels, dragonglass is found in quantity on Dragonstone and in the ruins of Valyria, where it was used to make different kinds of ornaments, including candles. It is also an export from Asshai. According to legend, the Children of the Forest also made use of the substance. Samwell Tarly discovered, by chance, that dragonglass is one of the few materials that can harm or kill Others. According to legend, the Children of the Forest would provide the Night's Watch with weapons made of dragonglass specifically for that purpose.
Stabbing an Other with dragonglass will cause it to melt into a puddle of very cold liquid, not shatter to pieces. Samwell later stabs a wight with a dragonglass dagger, but discovers that it has no more effect on wights than regular swords do.
There are old notes claiming that something called "dragon steel" is also lethal to the Others. Jon and Sam suspect this refers to Valyrian steel, but in the novels, the theory has not been put to test yet.
Dragonglass is sharper than steel, but also more brittle. For this reason it does not make good swords because they might shatter, but smaller daggers are more sturdy and therefore more common. They are also very effective as arrowheads.
In the books, it was Jon Snow who found the buried bundle. In it there were blades, a dozen knives, leaf-shaped spearheads, numerous arrowheads, and a broken warhorn.
Apart from its effectiveness against White Walkers and its use in magic, dragonglass is identical to real-world obsidian, down to its volcanic origins, its overall functional limitations, and its use as a reliable cutting tool by peoples who had yet to develop metallurgy. The World of Ice and Fire directly states that "obsidian" is what maesters officially call this type of volcanic rock, while "dragonglass" is a popular name for it used by the common people. That being said, it is often referred to as "dragonglass" in the novels, except for one or two points when a maester calls it "obsidian" (to point out to readers that "dragonglass" actually is "obsidian") and in A Storm of Swords, Samwell Tarly refers to it as "obsidian" a number of times. The Valyrian word for dragonglass translates as "frozen fire".
See alsoEdit
- Dragonglass on A Wiki of Ice and Fire (major spoilers from the books)
- ↑ Complete Guide to Westeros: Dragonstone
- ↑ "Cripples, Bastards and Broken Things"
- ↑ "The Prince of Winterfell"
- ↑ "The Climb"
- ↑ "Second Sons (episode)"
- ↑ Mhysa
- ↑ Kill the Boy
- ↑ "Hardhome"
- ↑ The Door


text:
You must be logged in to use this feature
Hi, I'm John Marazzi, owner of Brandon Honda. Do you have questions or comments for me? I'd love to hear them! Fill out the form and I will get back to you as soon as possible.
Thank you for visiting
Check us out on


text:
- ParaguayHealthFunding via Fundación Paraguaya
Alegre GroupParaguayClothingFunding via Fundación Paraguaya
HerminiaParaguayAgricultureFunding via Fundación Paraguaya
Valiant Women Of Pirayu Group
The leader of the group is Maria Antonia D.. She is an artisan in Nanduti where she lives with her partner, employed as a security guard, and their three children, all of whom are in school. Antonia is a very humble person and she lives in a small and precarious home but she is very hard working and responsible. She works every day tirelessly to generate more income for her home and to help with the daily expenses.
She will invest all of her loan in the purchase of fabrics and threads to weave Nanduti articles. Thanks to her work and her dedication that she puts into her work she always has many orders and her clients are always very satisfied.
She and her colleagues in the group are very thankful to Fundacion Paraguaya and to Kiva for the important support they are providing them through this loan.
La Presidenta del comité es la Sra. Maria Antonia D., ella se dedica a la Artesanía en Ñanduti (bordados), la misma vive con su pareja que es empleado (Guardia de Seguridad) y sus tres hijos que son estudiantes, doña Antonia es una persona muy humilde, vive en una casita precaria pero aun así es muy trabajadora y responsable, ella trabaja incansablemente todos los días para poder generar más ingresos en su hogar y así ayudar con los gastos diarios.
Ella destina todo su crédito a la compra de telas e hilos para realizar sus tejidos de ñanduti, gracias al empeño y la dedicación que ella le pone a su trabajo siempre tiene muchos pedidos y sus clientes quedan muy satisfechos.
Ella como todas sus compañeras de comité están muy agradecidas con la Fundación Paraguaya y Kiva por el importante apoyo que les están brindando con este crédito.
Additional Information
About Fundación ParaguayaFundación Paraguaya is a financially self-sustaining social enterprise that promotes entrepreneurship in urban and rural areas through microfinance, education programs, and more. Its focus on agriculture has helped many farmers boost their crop yields. And a number of other borrowers have taken out loans to start and grow social businesses that have helped deliver eyeglasses, medicines and other helpful services in their local communities.
This is a Group Loan
In a group loan, each member of the group receives an individual loan but is part of a larger group of individuals. The group is there to provide support to the members and to provide a system of peer pressure, but groups may or may not be formally bound by a group guarantee. In cases where there is a group guarantee, members of the group are responsible for paying back the loans of their fellow group members in the case of delinquency or default.
Kiva's Field Partners typically feature one borrower from a group. The loan description, sector, and other attributes for a group loan profile are determined by the featured borrower's loan. The other members of the group are not required to use their loans for the same purpose.
About Paraguay
47View loans »
Success!! The loan was 100% repaid
- Repayment Term
- 8 months (Additional Information)
- Repayment Schedule
- Monthly
- Pre-Disbursed:
- Feb 22, 2011
- Listed
- Mar 14, 2011
- Currency Exchange Loss:
- Covered
- Ended:
- Sep 15, 2011


text:
"Sölden, Skiing and Party in a great surrounding" Top 5 Page for this destination Sölden by mabu
Sölden Travel Guide: 64 reviews and 142 photos
I joined two friends who planned to go there for their skiing holiday. And what a great time we had!
Sölden is not only a place for some great skiing (or snowboarding if you like...) but the place to go if you like a good apres-ski and a good nightlife after skiing.
- Pros:Great skiing and a great nightlife in a nice Mountain surrounding
- Cons:The empty purse after a week... ;-)
- In a nutshell:Mountains, snow, party...
Reviews (14)
Not only in winter you can go skiing in Sölden. The Rettenbach and Tiefenbach glaciers allow skiing the whole year.... more travel advice
Of course Sölden has got modern chairlifts and cable cars too, realy most of them are prety new. There are some 2 and 4... more travel advice
In Winter you go to Sölden for a good Party and of course for Skiing and Snowboarding. There are lots of different... more travel advice
This is one of the oldest Chairlifts in Sölden, the Chairlift to Hochsölden. Its apparantly about 60years old. Its only... more travel advice
Comments (6)
tootal coole bilder von den alpen!! da bekommt man echt lust auf skifahren!!
a lovely page and great pics ! and that dish " Fuhre Mist " looks great and obviously tasted better than its name ! ;-))
winter wonder land :)
Sieht ja ganz nach Kaiserwetter aus. Merci für die ausführlichen Tips!
Looks lke you had fun :-)
mabu's Related Pages
Sölden Travel Guide
Member Travel Pages
- "Solden"
- "Sölden, Skiing and Party in a great surrounding"
- "The skiers highways"
- "Sölden - perpetual snowy paradise"
- "Soelden,Austria"
- "Solden Party"
- "Solden"
- See All...
- Things to Do in Sölden
- Hotels in Sölden
- Transportation in Sölden
- Nightlife in Sölden
- Restaurants in Sölden
- Warnings and Dangers in Sölden
- See All...
"Travelling is like a cocktail: a mix of new landscapes, new languages, new friends and it makes you feel good!"
- Member Rank:
- 0 1 1 9 7
- Forum Rank:
- 0 1 9 1 1
- 270 Reviews
- 752 Photos
- Add Friend
- Follow
- Send Message
Badges & Stats in Sölden
- 14 Reviews
- 15 Photos
- 0 Forum posts
- 6 Comments
- 2,209PageViews
- See All Stats
- See All Badges (24)
Have you been to Sölden?Share Your Travels
Latest Activity in Sölden
- updated a Sölden Travel Page "Sölden, Skiing and Party in a great surrounding"
- Posted in Travel Switzerland Forum "Re: Buying train tickets from..."
- Wrote a Review Skiing on the Glacier in Sölden Sports & Outdoors
- Uploaded a Photo to "Skiing on the Glacier"
Photos in SöldenSee All Photos (15)
Top 10 Pages
- Top 5 Page for this destination Bern Intro, 32 reviews, 71 photos, 5 travelogues
- Top 5 Page for this destination Taormina Intro, 33 reviews, 58 photos, 3 travelogues
- Switzerland Intro, 16 reviews, 62 photos, 4 travelogues
- Top 5 Page for this destination Bayahibe Intro, 24 reviews, 42 photos, 2 travelogues
- Norway Intro, 5 reviews, 47 photos, 5 travelogues
- Isla de Tenerife Intro, 12 reviews, 38 photos, 3 travelogues
- Majorca Island Intro, 6 reviews, 43 photos, 3 travelogues
- Top 5 Page for this destination Samnaun Intro, 12 reviews, 30 photos, 2 travelogues
- Vienna Intro, 11 reviews, 30 photos, 2 travelogues
- Sardegna Intro, 41 photos, 5 travelogues


text:
Credit : Snooki on Instagram
Celeb Instagram Pics: Snooki's Amazing Post-Baby Abs and More! (PHOTOS)
Our favorite celebrities continue to offer more glimpses into their personal and professional lives through Instagram!
Um, first of all, why does ;Snooki's ;post-baby body look better than our never-had-a-baby body? Dang it! Get ;this May 25 pic ;out of our faces.
Click through for the rest of the snapshots! ;


text:
Log In / Sign-Up | My Account | Customer Service
Log In / Sign-Up | My Account | Customer Service
sendLog In / Sign-Up |
The Polycom® CX500 IP phone features embedded Microsoft® Communicator "14" software, allowing it to be seamlessly deployed within Microsoft Communications Server "14" environments. Its clutter free design and large color display for viewing call and directory information provide the ultimate in calling convenience for common areas, such as lobbies, hallways and break rooms.and robust interoperability with the Communications Server "14" platform maximizing productivity for office and cubicle workers.
The Mitel 6721ip provides a lower cost option for users who require the benefits of a true IP phone, including dual Gigabit Ethernet ports and message waiting light indicator – but do not require the full UC desktop integration capabilities of the Mitel 6725ip. The Mitel 6721ip is an ideal selection for Hot-desking applications and common areas, such as lobbies and meeting rooms.
The Snom 760 features 3.5" color LCD display, support for 12 SIP lines, HD voice, and 2 Gigabit RJ45 ports.
The Mitel 6725ip is a true IP phone that provides the best Lync phone feature set available, including support of Microsoft's "Better Together" desktop link. The Mitel 6725ip allows PC desktop control of phone calling features such as transfer, hold, call park, conferencing and click-to-dial.
The Polycom® CX600 IP phone delivers all the features included in Microsoft® Communications Server "14" environments to provide a cost effective, mainstream. It features Polycom HD Voice™ technology for crystal-clear calls and robust interoperability with the Communications Server "14" platform maximizing productivity for office and cubicle workers.


text:
I and some colleagues (Phil Macnaghten from Durham/Unicamp and Brian Wynne from Lancaster) have been given a grant by the British Council and Fapesp to run a workshop on 'Responsible Innovation and the Governance of Socially Controversial Technologies' in Brazil on 19-21 March 2014.
If you are based in the UK or Brazil, are an early-career researcher (less than 10 years since PhD), have something interesting to say about responsibility and technology and fancy a trip to Brazil, email me (email@example.com) for an application form.
But you'll have to be quick. The deadline is 6th December.
Here's a recent paper that explains some of our thinking. And there's more info on the workshop below…


text:
A dministration of a balanced salt solution throughout the operative period during major abdominal surgery replaces extracellular fluid volume lost as a result of operative trauma.
Another Advantage
Moreover, correction of this volume deficit during surgery avoids postoperative salt intolerance, stated Charles J. Carrico, MD.In a clinical study by G. Tom Shires, MD, and his co-workers at University of Texas Southwestern Medical School, Dallas, C. Dale Coln, MD, and Dr. Carrico, plasma volume, erythrocyte mass, and extracellular fluid volume were followed in patients undergoing abdominal surgery uncomplicated by hypotension.Postoperative changes in extracellular fluid volume, other than that incurred as operative blood loss, could not be demonstrated in patients undergoing minor procedures.In patients undergoing major abdominal surgery, however, there was a decrease in extracellular fluid volume of up to 28% (3,721 cc) in those receiving only small intravenous amounts of 5% dextrose in water; this loss correlated only
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Need assistance?
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.


text:
This lovely young lady has been romantically involved with Middlesbrough defender Seb Hines but that's not important right now. A visual feast awaits.
WAG of the Week #122: Hot Busty British Glamour Model Chanelle Hayes (Sexy Image Gallery)
Use the ← → (arrow) keys to browse pages
Page 1 of 10Next >


text:
The opportunity to enjoy delicious food is closer than you think. Restaurant Jardí de Mar invites you to sample exquisite Mediterranean cuisine with international touches without having to hunt all over the city to find it.
This space in the Vincci Marítimo hotel in Barcelona is welcoming and comfortable. A practical room bathed in light, where you can feel completely at ease. Prepared by expert hands, the dishes include natural, high-quality ingredients, yet it is the passion for detail with which they are served that presents real added value, guaranteeing your utmost enjoyment.
Open to both guests and the general public, the hotel restaurant boasts an excellent location and is the perfect place to unwind after a busy day of sightseeing or shopping, or after a long day at work. And if you are staying in the hotel, it's an unbeatable opportunity to enjoy a delicious dinner just a few metres from your room. Dessert will be the icing on the cake.


text:
Nuclear inspection team highlights failures at San Onofre
A months-long inspection of the sidelined San Onofre nuclear plant found inaccurate computer modeling and construction shortcomings by an equipment manufacturer are behind rapid degradation of steam generator tubes that serve as a crucial barrier to radiation, nuclear safety regulators announced Monday.
A team of inspectors from the Nuclear Regulatory Commission told a packed public meeting in San Juan Capistrano that higher than expected steam flow velocities were rattling tubes within steam generators manufactured by Mitsubishi Heavy Industries.
"The computer simulation used by Mitsubishi to design the steam generators had underpredicted velocities of steam and water in the generators by factors of three and four times," said Greg Werner, a branch chief for the nuclear commission.
He added that manufacturing tolerances left the tubes sitting too loosely within support structures -- a problem that was especially pronounced in the Unit 3 reactor at the plant.
"So essentially the tubes are not held in place securely enough, so it allows them to slide or vibrate," Werner said. A full written report from the inspection team is due out within 30 days.
Original steam generators at the plant's twin 30-year-old reactors were replaced starting in 2009. Evidence of unusual wear on generator tubing turned up in January, with some of the equipment in service for only one year.
Analysis of the tube wear has looked at most conceivable sources of the rapid wear, from the manufacturing practices by Mitsubishi Heavy Industries in Kobe, Japan, to installation and plant operations at San Onofre.
It will next be up to plant operator Southern California Edison to submit a detailed restart plan that can satisfy a long list of safety commitments to regulators.
Werner emphasized that no decision has been made whether or how the plant might be restarted.
"The decision could be no restart," he said.
Edison executives made their own summary presentation Monday, endorsing the basic conclusions by the nuclear commission. Both regulators and the plant operator emphasized that no solution has been engineered yet for the tube wear.
"We are taking as much time as necessary to ensure this is understood and is properly corrected," said Thomas Palmisano, Edison's vice president of nuclear engineering at San Onofre.
Palmisano added that especially dry steam was contributing to vibrations and wear in the problem area, where nearly 10,000 tubes in each generator make a 180-degree turn. More water might otherwise dampen those vibrations.
Regulators and Edison officials, sitting at separate tables at the front of a community center auditorium, both deferred answering questions about the approval process for the generators, saying it was the focus of continued inspections.
When full costs are eventually calculated, recovery from ratepayers "will play out very publicly in front of the California Public Utilities Commission," said Peter Dietrich, Edison's chief nuclear officer at San Onofre.
The inspection team arrived at San Onofre in mid-March to study the extent and cause of tube degradation.
Several citizens' and nuclear activist groups held protests outside the meeting in San Juan Capistrano, several miles north of the San Onofre.
Monday's disclosures focused further attention on a series of alterations to the original equipment design and why the emerging problems went undetected by the manufacturer, plant operator and regulators.
Those alterations include the addition of 400 tubes to each generator and reconfiguring of supports intended to minimize tube wear and vibration.
The plant's four massive generators were designed to qualify as nearly identical equipment and forgo a license amendment that involves a more rigorous technical review.
Friends of the Earth, an international environmental group active on nuclear safety issues, has asserted for months that plant operator Southern California Edison played down the extent of design changes to the generators in order to avoid a license amendment.


text:
- Differential Diagnosis
- Diseases
- Drugs
- More
- Try building your search one term at a time, and be as specific as you can! Search term example: "chronic cough".
- Do not enter multiple findings such as "anemia, chronic cough, weight loss, vomiting" all at the same time.
- After selecting your term from the search results a list of possible diagnoses will be generated. If the list is too long, you will be able to narrow it down by entering additional terms.
- Do not enter values such as "heart rhythm 110" or "sodium 125", instead use "tachycardia" or "hyponatremia".
Sign-in (or register) to check out the new features we've just launched!
Differential Diagnosis For Sister Joseph node/umbilical adenopathy
Available only to registered users.
- Suggest
- 7 possible diagnoses found
- Neoplastic Disorders
- Metastatic malignancy (cancer)
- Adenocarcinoma, colon
- Adenocarcinoma, uterus
- Metastasis, lymph node
- Ovarian Cancer/Carcinoma
- Adenocarcinoma, gastric
- Adenocarcinoma, pancreatic
- Synonyms
- Lymph node cancer metastatic
- Definition
- Be the first to add a definition for Sister Joseph node/umbilical adenopathy
- External Links Related to Sister Joseph node/umbilical adenopathy
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)


text:
Recent Stories
Field cut to 8 teams, Wise wins individualMay 30, 2016 11:51 ET
EUGENE, Ore. -- Oregon sophomore Aaron Wise was crowned the 2016 NCAA individual champion, while the field in the team championship was narrowed to eight teams at the conclusion of the fourth round of stroke pl...
Eight teams advance to match playMay 30, 2016 11:23 ET
Stroke play concluded on Monday with the top teams advancing to match play on Tuesday. Texas earned the No. 1 seed.
DI Men's Golf: Aaron Wise wins the Individual National TitleMay 30, 2016 7:37 ET
Oregon's Aaron Wise wins the DI Men's Golf Individual National Championship at Eugene Country Club in Eugene, Oregon.
Vanderbilt maintains lead through Day 3May 29, 2016 6:01 ET
EUGENE, Ore. – Fifteen teams remain in contention after Sunday's third round of stroke play at the 2016 NCAA Division I Men's Golf Championships at Eugene Country Club, a par 70, 7,014-yard course. Led b...
Vanderbilt vaults into Day 2 leadMay 28, 2016 10:34 ET
EUGENE, Ore. – Vanderbilt put together an even-par round and moved ahead of the pack to lead after Saturday's second round of the 2016 NCAA Division I Men's Golf Championships at Eugene Country Club, a pa...
- Advertisement
- DI Golf ChampionshipMay 27-June 1, 2016Eugene, Oregon
Related Links


text:
Are you G Ciabattoni?Claim your profile
Publications (232)1383.14 Total impact
Article: Exhaled and non-exhaled non-invasive markers for assessment of respiratory inflammation in patients with stable COPD and healthy smokers[Show abstract] [Hide abstract] ABSTRACT: We aimed at comparing exhaled and non-exhaled non-invasive markers of respiratory inflammation in patients with chronic obstructive pulmonary disease (COPD) and healthy subjects and define their relationships with smoking habit. Forty-eight patients with stable COPD who were ex-smokers, 17 patients with stable COPD who were current smokers, 12 healthy current smokers and 12 healthy ex-smokers were included in a cross-sectional, observational study. Inflammatory outcomes, including prostaglandin (PG) E2 and 15-F2t-isoprostane (15-F2t-IsoP) concentrations in exhaled breath condensate (EBC) and sputum supernatants, fraction of exhaled nitric oxide (FENO) and sputum cell counts, and functional (spirometry) outcomes were measured. Sputum PGE2 was elevated in both groups of smokers compared with ex-smoker counterpart (COPD: P < 0.02; healthy subjects: P < 0.03), whereas EBC PGE2 was elevated in current (P = 0.0065) and ex-smokers with COPD (P = 0.0029) versus healthy ex-smokers. EBC 15-F2t-IsoP, a marker of oxidative stress, was increased in current and ex-smokers with COPD (P < 0.0001 for both) compared with healthy ex-smokers, whereas urinary 15-F2t-IsoP was elevated in both smoker groups (COPD: P < 0.01; healthy subjects: P < 0.02) versus healthy ex-smokers. FENO was elevated in ex-smokers with COPD versus smoker groups (P = 0.0001 for both). These data suggest that the biological meaning of these inflammatory markers depends on type of marker and biological matrix in which is measured. An approach combining different types of outcomes can be used for assessing respiratory inflammation in patients with COPD. Large studies are required to establish the clinical utility of this strategy.
- [Show abstract] [Hide abstract] ABSTRACT: Breathomics, the multidimensional molecular analysis of exhaled breath, includes analysis of exhaled breath with gas-chromatography/mass spectrometry (GC/MS) and electronic noses (e-noses), and metabolomics of exhaled breath condensate (EBC), a non-invasive technique which provides information on the composition of airway lining fluid, generally by high-resolution nuclear magnetic resonance (NMR) spectroscopy or MS methods. Metabolomics is the identification and quantification of small molecular weight metabolites in a biofluid. Specific profiles of volatile compounds in exhaled breath and metabolites in EBC (breathprints) are potentially useful surrogate markers of inflammatory respiratory diseases. Electronic noses (e-noses) are artificial sensor systems, usually consisting of chemical cross-reactive sensor arrays for characterization of patterns of breath volatile compounds, and algorithms for breathprints classification. E-noses are handheld, portable, and provide real-time data. E-nose breathprints can reflect respiratory inflammation. E-noses and NMR-based metabolomics of EBC can distinguish patients with respiratory diseases such as asthma, COPD, and lung cancer, or diseases with a clinically relevant respiratory component including cystic fibrosis and primary ciliary dyskinesia, and healthy individuals. Breathomics has also been reported to identify patients affected by different types of respiratory diseases. Patterns of breath volatile compounds detected by e-nose and EBC metabolic profiles have been associated with asthma phenotypes. In combination with other -omics platforms, breathomics might provide a molecular approach to respiratory disease phenotyping and a molecular basis to tailored pharmacotherapeutic strategies. Breathomics might also contribute to identify new surrogate markers of respiratory inflammation, thus, facilitating drug discovery. Validation in newly recruited, prospective independent cohorts is essential for development of e-nose and EBC NMRbased metabolomics techniques.
Article: Bronchodilating Drugs for Chronic Obstructive Pulmonary Disease: Current Status and Future Trends[Show abstract] [Hide abstract] ABSTRACT: Inhaled bronchodilators, including long-acting muscarinic receptor antagonists (LAMA) and long-acting beta2-adrenoreceptor agonists (LABA), are the mainstay of pharmacological treatment of stable chronic obstructive pulmonary disease (COPD). Among approved LAMA, tiotropium bromide, glycopyrronium bromide and umeclidinium bromide, are administered once daily, whereas aclidinium bromide is administered every 12 hours. New LAMA are under development for COPD. Among the approved LABA, indacaterol has a 24-h duration of action, whereas salmeterol and formoterol require twice-daily administration. New once-daily LABA, including vilanterol, olodaterol, milveterol, carmoterol, and abediterol, are in development. LAMA/LABA fixed dose combinations (FDC) provide the convenience of two bronchodilators with different mechanism of action in a single inhaler. Indacaterol/glycopyrronium, umeclidinium/vilanterol and olodaterol/tiotropium FDC, have been approved or are under approval and are likely to become a standard pharmacological strategy for COPD. Dual-pharmacology compounds, combining muscarinic antagonism and beta2-agonism (MABA) in a single molecule, potentially provide additive or synergistic bronchodilation over either inhaled antimuscarinic or beta2-agonist monotherapy.
- [Show abstract] [Hide abstract] ABSTRACT: Techniques are described in detail for the radioimmunological measurement of prostaglandin (PG) E2 and F2α in human urine. 50 ml urine samples are extracted with an organic solvent system and then purified by silicic acid column chromatography. The overall recovery after extraction and purification, calculated with labeled as well as unlabeled compounds, is in the order of 70%. The column eluates are assayed at 1:12–1:60 dilution in the "standard diluent" of the assay: 8 pg PGE2.or PGF2a/ml of whole urine represents the lowest measurable concentration. A urine blank and a solvent blank were evaluated separately, subjecting 50 ml of urine obtained from an indomethacin treated subject ("PG-free" urine) or 50 ml of distilled water, respectively, to the extraction-purification procedures. Both were found not to interfere with the antigen-antibody reaction. Urinary PG-like immunoreactivity (LI) was characterized in terms of immunochemical and thin-layer chromatographic (TLC) behavior. Both urinary PGE2-LI and PGF2α-LI behaved as authentic PGE2 and PGF2α, upon dilution and on TLC. In 33 healthy female subjects (aged 19–58 yr), urinary excretion rates averaged 178 ± 80 (mean ± SD) ng/day for PGE2 and 498 ± 181 ng/day for PGF2α. In a group of 8 healthy men, both PGE2 and PGF2α crexcretion rates were higher and more scattered than the female values. When two healthy women were given indomethacin (200 mg/day), urinary PGE2 and PGF2α dropped to undetectable levels during the 4th day of drug therapy. I ntravenous injection of furosemide (50 mg) in a female volunteer was followed by an immediate rise of urinary sodium, PGE2, PGF2α and PGE2/PGF2α ratio and plasma renin activity. Ina 10 year old girl with Bartter's syndrome, urinary PG excretion rate was elevated with a 3 times higher than normal PGE2/PGF2α ratio. Indomethacin therapy resulted in a prompt drop of PG excretion rate and of plasma renin activity. These results show that a combi nation of adequate purification steps and antisera with optimal characteristics provides a reliable method for measuring PGE2 and PGF2α in urine, and therefore a valuable tool to further our knowledge of the physiology and physiopathology of the renal PG-system.
Article: Exhaled breath condensate, nasal eosinophil cationic protein level and nasal cytology during immunotherapy for cypress allergy[Show abstract] [Hide abstract] ABSTRACT: Interest in cypress allergy is widely rising: an increasing number of studies have pointed out the efficacy of immunotherapy to reduce cypress-related symptoms and drug use. Cypress immunotherapy is well tolerated, but there are few studies dealing with its sub-clinical effects on the airways. The aim of this investigation is to assess the effects of immunotherapy on airways by the analysis of exhaled breath condensate (EBC), nasal lavage fluid (NAL) and nasal cytology. Fifteen mono-sensitized to cypress pollen patients have been observed, among them 9 have been treated with sub-cutaneous immunotherapy (SCIT), 3 with sub-lingual immunotherapy (SLIT) and 3 which were not treated underwent EBC, NAL and nasal cytology out of the pollen season. 8-isoprostane in EBC, Eosinophil cationic protein (ECP) and inflammatory cells in nasal cytology were also evaluated. The median value of 8-isoprostane in EBC was 18.58 pg/ml in patients who did not undergo immunotherapy, 49.38 pg/ml in SCIT patients and 13.41 pg/ml in SLIT subjects. The median value of ECP in nasal lavage was higher in non- treated subjects (27.3 mg/l) than in those treated with SCIT (1 mg/l)(p less than 0,05) or SLIT (2.6 mg/l). All nasal cytology specimens did not show any sign of inflammation. In conclusion SLIT seems to be well tolerated and to reduce significantly the levels of ECP in nasal lavage. In addition the levels of 8-isoprostane in EBC among SCIT patients were unexpectedly high and need to be further evaluated.
Article: Oxidative stress and platelet activation in subjects with moderate hyperhomocysteinaemia due to MTHFR 677 C→T polymorphism[Show abstract] [Hide abstract] ABSTRACT: The methylenetetrahydrofolate reductase (MTHFR) 677 C→T polymorphism may be associated with elevated total homocysteine (tHcy) levels, an independent risk factor for cardiovascular disease. It was the study objective to evaluate in vivo lipid peroxidation and platelet activation in carriers of the MTHFR 677 C→T polymorphism and in non-carriers, in relation to tHcy and folate levels. A cross-sectional comparison of urinary 8-iso-prostaglandin (PG)F2α and 11-dehydro-thromboxane (TX)B2 (markers of in vivo lipid peroxidation and platelet activation, respectively) was performed in 100 carriers and 100 non-carriers of the polymorphism. A methionine-loading test and folic acid supplementation were performed to investigate the causal relationship of the observed associations. Urinary 8-iso-PGF2α and 11-dehydro-TXB2 were higher in carriers with hyperhomocysteinaemia than in those without hyperhomocysteinaemia (p<0.0001). Hyperhomocysteinaemic carriers had lower folate levels (p=0.0006), higher urinary 8-iso-PGF2α (p<0.0001) and 11-dehydro-TXB2 (p<0.0001) than hyperhomocysteinaemic non-carriers. On multiple regression analysis, high tHcy (p<0.0001), low folate (p<0.04) and MTHFR 677 C→T polymorphism (p<0.001) independently predicted high rates of 8-iso-PGF2α excretion. Methionine loading increased plasma tHcy (p=0.002), and both urinary prostanoid metabolites (p=0.002). Folic acid supplementation was associated with decreased urinary 8-iso-PGF2α and 11-dehydro-TXB2 excretion (p<0.0003) in the hyperhomocysteinaemic group, but not in the control group, with substantial inter-individual variability related to baseline tHcy level and the extent of its reduction. In conclusion, hyperhomocysteinaemia due to the MTHFR 677 C→T polymorphism is associated with enhanced in vivo lipid peroxidation and platelet activation that are reversible, at least in part, following folic acid supplementation. An integrated biomarker approach may help identifying appropriate candidates for effective folate supplementation.
Article: Montuschi P, Paris D, Melck D, Lucidi V, Ciabattoni G, Raia V et al.. NMR spectroscopy metabolomic profiling of exhaled breath condensate in patients with stable and unstable cystic fibrosis. Thorax 67: 222-228[Show abstract] [Hide abstract] ABSTRACT: Metabolomics could provide new insights into the pathophysiology of cystic fibrosis (CF) by identifying profiles of endogenous metabolites. To investigate whether metabolomics of exhaled breath condensate could discriminate between patients with unstable CF, stable CF and healthy subjects, and whether selected metabolites were responsible for between-group differences. Twenty-nine patients with stable CF, 24 with unstable CF and 31 healthy subjects (age 9-24 years) participated in a cross-sectional study. Metabolomics was performed with high-resolution nuclear magnetic resonance spectroscopy. Partial least squares-discriminant analysis was used as classifier. The results were validated in a second independent study. Intraclass correlation coefficients for between-day and technical repeatability were 0.93 and 0.96, respectively. Bland-Altman analysis showed good within-day repeatability. Correct classification rate of CF (n=53) vs. healthy subjects (n=31) was 96% (R2=0.84; Q2=0.79). Model validation with a testing sample set obtained from subjects not included in the primary analysis (23 CF and 25 healthy subjects) showed a sensitivity of 91% and a specificity of 96%. The classification rate of stable CF (n=29) vs. unstable CF patients (n=24) was 95% (R2=0.82; Q2=0.78). Model external validation in 14 patients with stable CF and 16 with unstable CF showed a sensitivity of 86% and a specificity of 94%. Ethanol, acetate, 2-propanol and acetone were most discriminant between patients with CF and healthy subjects, whereas acetate, ethanol, 2-propanol and methanol were the most important metabolites for discriminating between patients with stable and unstable CF. Nuclear magnetic resonance spectroscopy of exhaled breath condensate is reproducible, discriminates patients with CF from healthy subjects and patients with unstable CF from those with stable CF, and identifies the metabolites responsible for between-group differences.
Conference Paper: NMR Metabolomic Profiling Of Exhaled Breath Condensate In Children And Adolescents With Stable And Unstable Cystic Fibrosis
Article: Effects of atorvastatin and rosuvastatin on thromboxane-dependent platelet activation and oxidative stress in hypercholesterolemia[Show abstract] [Hide abstract] ABSTRACT: We examined the time-dependent effects of atorvastatin and rosuvastatin on in vivo oxidative stress and platelet activation, to assess whether these phenomena are related to any pleiotropic effect of any statin or to their LDL-lowering effect. We also asked whether the presence of specific allele frequencies in carriers of the 3'UTR/lectin-like oxidized LDL receptor-1 (LOX-1) polymorphism may influence the effect of either statin. We included 60 hypercholesterolemic subjects, previously screened for LOX-1 3'UTR polymorphism, randomized, according to genetic profile (15 T and 15 C carriers for each arm), to atorvastatin 20mg/day or rosuvastatin 10mg/day. After 8 weeks, atorvastatin and rosuvastatin were associated with comparable, significant reductions in LDL cholesterol (40.8% and 43.6%, respectively), plasma hs-CRP (9.5% vs. 13.8%), urinary 11-dehydro-thromboxane (TX) B(2) (38.9% vs. 27.1%) and 8-iso-prostaglandin (PG) F(2α) (39.4% vs. 19.4%). The impact of rosuvastatin or atorvastatin on CRP, 8-iso-PGF(2α), and 11-dehydro-TXB(2) did not differ according to the LOX-1 haplotype. On multiple regression analyses, only CRP and LDL were independent predictors of 11-dehydro-TXB(2), and only LDL was a significant predictor of 8-iso-PGF(2α). Both atorvastatin and rosuvastatin cause comparable reductions of thromboxane-dependent platelet activation, lipid peroxidation and inflammation. The presence of 3'UTR/LOX-1 polymorphism does not affect the changes induced by either statin.
Article: Novel perspectives in the detection of oral and nasal oxidative stress and inflammation in pediatric united airway diseases[Show abstract] [Hide abstract] ABSTRACT: United airway disease (UAD) concept proposed that asthma and rhinitis are both different clinical manifestation of a single inflammatory process. The aim of this study is to assess in upper and lower airways the level of inflammation and oxidative stress and to investigate the relationship between biomarkers in persistent allergic rhinitis (PER) and in concomitant asthma with PER. By a crosssectional study we measured oral and nasal (FENO) and oral and nasal EBC 8-isoprostane, LTB4 and PGE2 in children with PER (n=14) and with PER and concomitant intermittent asthma (IA; n=25), mild persistent asthma (mA; n=28), moderate persistent asthma (MA; n=13) and in Healthy Controls (HCs; n=13). Oral and nasal FENO concentrations were increased in children with PER, IA, mA and MA when compared with HCs. Nasal 8-isoprostane was higher in EBC of children with PER and asthma than in HCs. Oral and nasal LTB4 were higher in EBC of children with PER and mA than in HCs. Oral and nasal PGE2 concentrations were higher in EBC of children with PER than in HCs. Positive correlations between oral and nasal biomarkers were found in IA for LTB4 and PGE2, in mA for FENO, 8-isoprostane, LTB4 and PGE2, and in MA for PGE2. No correlations were observed in children with PER and HCs. Our results suggest that non-invasive markers of inflammation and oxidative stress might be useful to study the relationships between oral and nasal compartments in allergic children with PER and concomitant asthma with the aim of defining the UAD.
Article: Determinants of Thromboxane Biosynthesis in Rheumatoid Arthritis: Role of RAGE and Oxidant Stress[Show abstract] [Hide abstract] ABSTRACT: Thromboxane (TX) biosynthesis by platelets and other cells in response to inflammatory triggers may provide a link between chronic inflammatory disease and atherothrombosis in rheumatoid arthritis (RA). In this study, we investigated the determinants of TX biosynthesis in RA, with particular reference to enhanced oxidative stress, receptor for advanced glycation end-products (RAGE) hyperactivity, and anti-tumor necrosis factor (TNF) treatment. Fifty-four patients with RA and 20 healthy subjects were recruited and a cross-sectional comparison of urinary 11-dehydro-TXB(2), 8-iso-PGF(2alpha), and plasma endogenous secretory RAGE (esRAGE) levels was performed between patients and controls. Urinary 11-dehydro-TXB(2) was significantly higher in RA patients than in healthy controls [425 (309-592) vs 233 (158-327) pg/mg creatinine, P<0.0001]. Furthermore, urinary 8-iso-PGF(2alpha) [323 (221-515) vs 172 (91-292) pg/mg creatinine, P<0.0001] and plasma esRAGE [155 (100-240) vs 377 (195-486) pg/ml, P=0.001] were higher and lower, respectively, in patients than in controls. A direct correlation was found between urinary 11-dehydro-TXB(2) and 8-iso-PGF(2alpha) only in patients not on anti-TNF therapy (r=0.420, P=0.021). Conversely, patients on anti-TNF therapy showed significantly lower urinary 8-iso-PGF(2alpha) [284 (201-373) vs 404 (241-539) pg/mg creatinine, P=0.043] but not 11-dehydro-TXB(2) than anti-TNF-treated subjects, with esRAGE as the only independent predictor of 11-dehydro-TXB(2) in this group of patients (adjusted R(2)=0.496, beta=-0.725, SEM=0.025, P=0.001). In conclusion, we provide biochemical evidence of enhanced TX biosynthesis in patients with RA, driven, at least in part, by lipid peroxidation. Treatment with anti-TNF agents may blunt isoprostane generation in the absence of significant effects on TX biosynthesis. We suggest that RAGE hyperactivity may escape TNF blockade, thus contributing to persistent TX biosynthesis in this setting.
Conference Paper: Biomarkers Of Inflammation And Oxidative Stress In Patients With COPD And Healthy Smokers
Article: Postprandial hyperglycemia is a determinant of platelet activation in early type 2 diabetes mellitus[Show abstract] [Hide abstract] ABSTRACT: Chronic hyperglycemia is a major contributor to in vivo platelet activation in diabetes mellitus. To evaluate the effects of acarbose, an alpha-glucosidase inhibitor, on platelet activation and its determinants in newly diagnosed type 2 diabetic patients. Forty-eight subjects (26 males, aged 61 +/- 8 years) with early type 2 diabetes (baseline hemoglobin A(1c) < or = 7% and no previous hypoglycemic treatment) were randomly assigned to acarbose up to 100 mg three times a day or placebo, and evaluated every 4 weeks for 20 weeks. The main outcome measures were urinary 11-dehydro-thromboxane (TX)B(2) (marker of in vivo platelet activation) and 8-iso-prostaglandin (PG)F(2alpha) (marker of in vivo lipid peroxidation) excretion rate, 2-h postprandial plasma glucose (PPG) after a test meal, and assessment of glucose fluctuations by mean amplitude of glycemic excursions (MAGE). Baseline measurements revealed biochemical evidence of enhanced lipid peroxidation and platelet activation. As compared with the placebo group, patients treated with acarbose had statistically significant reductions in urinary 11-dehydro-TXB(2) and 8-iso-PGF(2alpha) excretion rate as early as after 8 weeks and at each subsequent time point (between-group P < 0.0001 at 12, 16 and 20 weeks), following earlier decreases in PPG and MAGE. Multiple regression analyses in the acarbose group revealed that PPG was the only significant predictor of 11-dehydro-TXB(2) urinary excretion rate (beta = 0.39, P = 0.002) and MAGE the only predictor of 8-iso-PGF(2alpha) urinary excretion rate (beta = 0.42, P = 0.001). Postprandial hyperglycemia is associated with enhanced lipid peroxidation and platelet activation in early type 2 diabetes. A moderate decrease in PPG achieved with acarbose causes time-dependent downregulation of these phenomena, suggesting a causal link between early metabolic abnormalities and platelet activation in this setting.
Article: Diagnostic Performance Of An Electronic Nose, Fractional Exhaled Nitric Oxide And Lung Function Testing In Asthma[Show abstract] [Hide abstract] ABSTRACT: Analysis of exhaled breath by biosensors discriminates between patients with asthma and healthy subjects. An electronic nose consists of a chemical sensor array for the detection of volatile organic compounds (VOCs) and an algorithm for pattern recognition. We compared the diagnostic performance of a prototype of an electronic nose with lung function tests and fractional exhaled nitric oxide (FENO) in patients with atopic asthma. A cross-sectional study was undertaken in 27 patients with intermittent and persistent mild asthma and in 24 healthy subjects. Two procedures for collecting exhaled breath were followed to study the differences between total and alveolar air. Seven patients with asthma and seven healthy subjects participated in a study with mass spectrometry (MS) fingerprinting as an independent technique for assessing between group discrimination. Classification was based on principal component analysis and a feed-forward neural network. The best results were obtained when the electronic nose analysis was performed on alveolar air. Diagnostic performance for electronic nose, FENO, and lung function testing was 87.5%, 79.2%, and 70.8%, respectively. The combination of electronic nose and FENO had the highest diagnostic performance for asthma (95.8%). MS fingerprints of VOCs could discriminate between patients with asthma and healthy subjects. The electronic nose has a high diagnostic performance that can be increased when combined with FENO. Large studies are now required to definitively establish the diagnostic performance of the electronic nose. Whether this integrated noninvasive approach will translate into an early diagnosis of asthma has to be clarified. Trial registration: EUDRACT https://eudralink.emea.europa.eu; Identifier: 2007-000890-51; and clinicaltrials.gov; Identifier: NCT00819676.
Article: Thromboxane and prostacyclin biosynthesis in heart failure of ischemic origin: Effects of disease severity and aspirin treatment[Show abstract] [Hide abstract] ABSTRACT: Thromboembolism is a relatively common complication of chronic heart failure (HF) and the place of antiplatelet therapy is uncertain. We characterized the rate of thromboxane and prostacyclin biosynthesis in chronic HF of ischemic origin, with the aim of separating the influence of HF on platelet activation from that of the underlying ischemic heart disease (IHD). We compared urinary 11-dehydro-thromboxane (TX)B(2), 2,3 dinor 6-keto-PGF(1alpha,) 8-iso-prostaglandin (PG)F(2alpha), and plasma N-terminal pro-brain natriuretic peptide (NT-pro-BNP), asymmetric dimethylarginine (ADMA), and soluble CD40 ligand (sCD40L), in 84 patients with HF secondary to IHD, 61 patients with IHD without HF and 42 healthy subjects. HF patients not on aspirin had significantly higher urinary 11-dehydro-TXB(2) as compared with healthy subjects (P < 0.0001) and IHD patients not on aspirin (P = 0.028). They also showed significantly higher 8-iso-PGF(2alpha) (P = 0.018), NT-pro-BNP (P = 0.021) and ADMA (P < 0.0001) than IHD patients not on aspirin. HF patients on low-dose aspirin had significantly lower 11-dehydro-TXB(2) (P < 0.0001), sCD40L (P = 0.007) and 2,3-dinor-6-keto-PGF(1alpha) (P = 0.005) than HF patients not treated with aspirin. HF patients in NYHA classes III and IV had significantly higher urinary 11-dehydro-TXB(2) than patients in classes I and II, independently of aspirin treatment (P < 0.05). On multiple linear regression analysis, higher NT-pro-BNP levels, lack of aspirin therapy and sCD40L, predicted 11-dehydro-TXB(2) excretion rate in HF patients (R(2) = 0.771). Persistent platelet activation characterizes HF patients. This phenomenon is related to disease severity and is largely suppressable by low-dose aspirin. The homeostatic increase in prostacyclin biosynthesis is impaired, possibly contributing to enhanced thrombotic risk in this setting.
- [Show abstract] [Hide abstract] ABSTRACT: Oxidative stress is functionally involved in the pathophysiology of lung diseases including asthma and chronic obstructive pulmonary disease. 8-Isoprostane, which is derived from free radical-catalyzed peroxidation of arachidonic acid, is one of the most reliable biomarkers of oxidative stress. Exhaled breath condensate (EBC) is a completely noninvasive method for collecting airway secretions. We developed a specific and sensitive radioimmunoassay (RIA) that has been applied to the measurement of 8-isoprostane in EBC. This RIA for 8-isoprostane has been validated using high performance liquid chromatography. Measurement of 8-isoprostane in EBC is a useful noninvasive technique for exploring the role of oxidative stress in lung diseases. This technique might provide important insights into the understanding of the clinical pharmacology of antioxidants and might be useful for monitoring the effects of pharmacological therapy.
Article: The contribution of cyclooxygenase-1 and -2 to persistent thromboxane biosynthesis in aspirin-treated essential thrombocythemia: Implications for antiplatelet therapy[Show abstract] [Hide abstract] ABSTRACT: We tested whether cyclooxygenase 2 (COX-2) expression and unacetylated COX-1 in newly formed platelets might contribute to persistent thromboxane (TX) biosynthesis in aspirin-treated essential thrombocythemia (ET). Forty-one patients on chronic aspirin (100 mg/day) and 24 healthy subjects were studied. Platelet COX-2 expression was significantly increased in patients and correlated with thiazole orange-positive platelets (r = 0.71, P < .001). The rate of TXA(2) biosynthesis in vivo, as reflected by urinary 11-dehydro-TXB(2) (TXM) excretion, and the maximal biosynthetic capacity of platelets, as reflected by serum TXB(2), were higher in patients compared with aspirin-treated healthy volunteers. Serum TXB(2) was significantly reduced by the selective COX-2 inhibitor NS-398 added in vitro. Patients were randomized to adding the selective COX-2 inhibitor, etoricoxib, or continuing aspirin for 7 days. Etoricoxib significantly reduced by approximately 25% TXM excretion and serum TXB(2). Fourteen of the 41 patients were studied again 21 (+/- 7) months after the first visit. Serum TXB(2) was consistently reduced by approximately 30% by adding NS398 in vitro, while it was completely suppressed with 50 microM aspirin. Accelerated platelet regeneration in most aspirin-treated ET patients may explain aspirin-persistent TXA(2) biosynthesis through enhanced COX-2 activity and faster renewal of unacetylated COX-1. These findings may help in reassessing the optimal antiplatelet strategy in ET.
Article: Soluble CD40L in Mediterranean Spotted Fever: Relation to oxidative stress and platelet activation
Article: Acute Effects of Air Pollution on Pulmonary Function, Airway Inflammation, and Oxidative Stress in Asthmatic Children[Show abstract] [Hide abstract] ABSTRACT: Air pollution is associated with respiratory symptoms, lung function decrements, and hospitalizations. However, there is little information about the influence of air pollution on lung injury. In this study we investigated acute effects of air pollution on pulmonary function and airway oxidative stress and inflammation in asthmatic children. We studied 182 children with asthma, 9-14 years of age, for 4 weeks. Daily ambient concentrations of sulfur dioxide, nitrogen dioxide, ozone, and particulate matter < or = 2.5 microm in aerodynamic diameter (PM(2.5)) were monitored from two stations. Once a week we measured spirometry and fractional exhaled nitric oxide (FeNO), and determined thiobarbituric acid reactive substances (TBARS) and 8-isoprostane--two oxidative stress markers--and interleukin-6 (IL-6) in breath condensate. We tested associations using mixed-effects regression models, adjusting for confounding variables. Interquartile-range increases in 3-day average SO2 (5.4 ppb), NO2 (6.8 ppb), and PM(2.5) (5.4 microg/m3) were associated with decreases in forced expiratory flow between 25% and 75% of forced vital capacity, with changes being -3.1% [95% confidence interval (CI), -5.8 to -0.3], -2.8% (95% CI, -4.8 to -0.8), and -3.0% (95% CI, -4.7 to -1.2), respectively. SO2, NO2, and PM(2.5) were associated with increases in TBARS, with changes being 36.2% (95% CI, 15.7 to 57.2), 21.8% (95% CI, 8.2 to 36.0), and 24.8% (95% CI, 10.8 to 39.4), respectively. Risk estimates appear to be larger in children not taking corticosteroids than in children taking corticosteroids. O3 (5.3 ppb) was not associated with health end points. FeNO, 8-isoprostane, and IL-6 were not associated with air pollutants. Air pollution may increase airway oxidative stress and decrease small airway function of asthmatic children. Inhaled corticosteroids may reduce oxidative stress and improve airway function.
Top Journals
Università degli Studi G. d'Annunzio Chieti e Pescara
Chieta, Abruzzo, Italy
- Dipartimento di Medicina e Scienze dell'Invecchiamento
University of MilanMilano, Lombardy, Italy
Sapienza University of RomeRoma, Latium, Italy
Erasmus Universiteit Rotterdam
Rotterdam, South Holland, Netherlands
- Department of Neurology
The Catholic University of AmericaWashington, Washington, D.C., United States
University of FreiburgFreiburg, Baden-Württemberg, Germany


text:
Mariners' Pineda shuts down Phillies
SEATTLE Phillies All-Star Roy Oswalt was no match for Mariners rookie Michael Pineda.
Pineda wriggled out of a jam in the sixth after giving up his first hit, outpitching Oswalt and helping the Seattle Mariners end the Phillies' season-high seven-game winning streak with a 4-2 victory Friday night.
Oswalt (4-5), who has won just once since April 21, went 6 1-3 innings, allowing four runs and eight hits. He walked two and struck out three.
Entering the game, Oswalt had allowed one earned run or fewer in eight if his previous 10 road starts.
"I felt pretty good early," Oswalt said. "I was throwing the normal speed I always throw. I just left the ball over the plate to (Miguel) Olivo and I thought I had (Justin) Smoak popped up on the infield (in the fifth) and it went a little further than I thought it would."
Olivo hit his 11th home run for the Mariners while Victorino had his seventh for the Phillies.
Entering the sixth, Pineda (7-4) had a 3-0 lead and no-hitter but Shane Victorino singled to right with two outs and a runner on. Then Chase Utley followed with an RBI single. That brought up Howard, with 15 home runs and 57 RBIs.
"I did not want to make mistake for him," Pineda said. "I need to make my pitches because he's a good hitter."
He made his pitches so Howard couldn't hit them, walking him on five pitches to load the bases. That allowed Pineda to focus on Placido Polanco. He struck him out on three pitches - a checked swing called by home umpire Doug Eddings.
"He felt like the guy called a check-swing strike and didn't check with another umpire," said Phillies manager Charlie Manuel, who trotted out to break up Polanco's debate with Eddings.
Pineda went six innings, allowing the two hits and one run. He walked three and struck out five.
Ichiro Suzuki, the two-time batting champion, had three hits and has six straight multihit games to raise his average from .252 to .275.
Brendan Ryan had two hits and two RBIs.
Dustin Ackley, the second pick in the 2009 draft, called up before the game, stroked his first big league hit - a single through Roy Oswalt's legs - in his first at-bat in the second inning.
It's the first time a Mariners player had a hit in his first career plate appearance since Wladimir Balentien on Sept. 4, 2007.
Aaron Laffey worked two innings - giving up Victorino's solo shot in the eighth - before yielding to Brandon League in the ninth.
Brandon League earned his 21st save in 24 opportunities. He now leads the majors in saves.
"He (Pineda) was good. He was real good. He was very good," Manuel said. "He looked a little spent at the end. We didn't hit very many balls hard the first five, six innings. He mixed his pitches good and he's big and strong."
Suzuki pestered Oswalt throughout. He reached on a one-out infield single in the third. Ryan then drilled a first-pitch RBI triple into the right-center gap.
In the fourth, Olivo hit a 2-0 pitch over the left-field wall for a 2-0 lead.
Suzuki opened the fifth with a single and Ryan walked. Adam Kennedy advanced both with a sacrifice bunt. Justin Smoak lifted a foul fly down the right-field line. Utley, with his back to home, caught it and Suzuki alertly tagged and scored easily.
"I hollered at him to tag up but he was coming back anyway," third base coach Jeff Datz said. "When Utley caught the ball, yes, we're going to go. If (right fielder) Domonic Brown had caught it, depending on where he was, he has a much better arm and maybe we stay."


text:
Here's a list of some famous and perhaps a few not so famous cat quotes for your entertainment. Cat lovers will instantly have an "ah ha!" moment when reading some of these. I know I did when I first read them.
With over 2 million copies in print, this book is filled with some of
the most famous cat quotes ever, all from lessons taught to Suzy by her
beloved cat, Binky. It's a great book for cat lovers.
Cats and People
Famous Cats
Cat Lovers Only
Like this page
Like us on Facebook
Like us on Facebook
10 Cutest Kitten Moments with Marmalade and Cole
23 Cats Who Love Boxes. "Bonus Belle" is my favorite. What's Yours?
Celebrate the antics and adventures of Buddy and Emma. The 143 comic strips featuring these brother and sister barn cats ran on the internet from 2003
Spike was 16 years old. We got him when he was a baby and he was brought up with my 3 children. He was more than a pet, he was my fourth child. 29th April,
One of our readers is considering purchasing a cat health insurance policy for her three cats. Do you think this is a good investment?
How to Give 7 Maine Coon Kittens an Eye Test
Mama cat adopts orphaned baby bunny
Which Low Cost Cat Food is the Best?
Cat Welcomes Home Soldier with a Meow and a Hug!
Adorable Orange Kitten Stalks Himself on Video
Weatherman Rescues Kitten from Tornado Rubble
Kevin Richardson Snuggles with Lions
Abandoned Puppy + Starving Kitten = ??
Dogs Annoying Cats with Friendship
Shhhhh... Do Not Disturb. Adorable Kitten is So Tired!
These Two Flea Infested Kittens Had No Future, Until This Happened
You've Never Seen a Dog Show This Much Love for Foster Kittens. Until Now.
This Great Dane and Kitten Have a Love Story for the Ages. Tissue Alert.


text:
With less than a month until the Oscars, a host of Hollywood A-Listers gathered at the Beverly Hills Hilton Hotel this afternoon (February 10) for the Academy Awards Nominees Luncheon.
He's all over the place nowadays as his film "Dallas Buyers Club" is up for many accolades, but Jared Leto is fully prepared for this awards season.
Sharing some insight to what goes on behind-the-scenes at the shows that the public may not be aware of, the Oscar-nominated actor explains that they "last for sometimes hours and hours and hours."
Ready to celebrate his immense success, Jared Leto arrived at the 2014 Academy Awards nominees luncheon in Beverly Hills, CA on Monday (February 10).
Celebrating the achievements of some of Hollywood's great talents, stars flocked to the 29th Santa Barbara International Film Festival Virtuosos Awards last night (February 4).
He's getting all kinds of recognition for his role in "Dallas Buyers Club" and last night (February 3) Jared Leto dropped by American Cinematheque for a Q&A with his fans.
The "Requiem For a Dream" hunk looked handsome as he addressed the crowd at the Egyptian Theatre in Hollywood and posed for pictures.
We're deep in the midst of awards season, and Vanity Fair collected a ton of big-name celebrities for their 20th Annual Hollywood Issue.
Stepping out for day two of international promotional duties, Jared Leto dropped by BBC Radio 2 studios in London on Thursday morning (January 30).
The 30 Seconds to Mars frontman stopped to sign autographs and posed for a few snapshots before making his way into the studio to chat about his award winning film "Dallas Buyers Club."
Taking care of some international promotional duties, Jared Leto headed over to BBC Radio One studios in London, England on Wednesday morning (January 29).
The "Kings and Queens" rocker was in the house to chat about his new film "Dallas Buyers Club," (he's up for a Best Supporting Actor Oscar) and gave fans the 'thumbs up' as he exited the building en route to his next stop.


text:
- Text Size:
- ASmall Text
- AMedium Text
- ALarge Text
On Tuesday morning, another bill is on the way to Gov. Steve Beshear's desk, allowing doctors at two Kentucky hospitals to prescribe medicine derived from marijuana oil.
It will be used treat child seizures.
The bill would allow Kentuckians to use it in two cases: A prescription from a doctor at the University of Louisville or UK research hospitals or a trial from the FDA.


text:
Salvador Larroca is a Spanish artist who works for Marvel. He began his career working for the company that published Marvel comics in Spain. He then joined Marvel UK, where he did 'Dark Angel' and 'Death's Head'. Afterwards, he drew 'The Flash' for DC. He worked on 'Ghost Rider' for three years, followed by the 'Excalibur' mini-series. He was a regular artist on the 'Fantastic Four', and he has done pencil work for 'X-Treme X-Men' and 'Uncanny X-Men'.
Artwork © 2016 Salvador Larroca
Website © 1994-2016 Lambiek
Laatste update: 2008-01-18
Series en boeken door Salvador Larroca op voorraad in de Lambiek Webshop:
If you want to help us continue and improve our ever- expanding database, we would appreciate your donation through Paypal.


text:
The browser version you are using is not supported by Kiva. Please use the most recent version of these supported browsers for Kiva to function properly.
Sign in
My Basket
Check out some available loans that are similar to this one!
Meyling Raquel
Funding via MiCredito
Lend Now
Flavia Fran...
Funding via MiCredito
Lend Now
Martha Jacinta
Funding via MiCredito
Lend Now
Chontales, Nicaragua
Loan Overview
Repayment Schedule
Loan Updates
Mr. Agustin is married and is 48 years old. He has worked in the Alcaldia Muncipal of Juigalpa as a guard for 6 years. His wife doesn't work outside the house. She washes and irons during the week. She uses the money she earns for the expenses, and his salary is used to pay his loans and to fund unexpected expenses. Their children are adults and aren't under their responsibility. They have only one child who is in secondary school. This client is requesting his second loan, which will be used to build a bathroom and sanitary services inside her house with the intention of offering security to his family so that they won't have to go out to the patio. This is important because the women are sometimes in the house alone at night when he is working. Some days, he works during the days and other days during the nights. His first loan was used to improve his home, since it is difficult to put together enough money to buy foundation slabs. With the loan, he agrees that each month, after the payment, he has to pay the installment that is already established.
Translated from Spanish
Kiva volunteer
Avni Shah
View original language description ↓
Don Agustin es casado, de 48 años de edd, con 6 años de servicio en la Alcaldia Municipal de Juigalpa como vigilante, su esposa no trabaja fuera de su casa, lava y plancha durante la semana, con el dinero que gana lo utilizan para los gastos de la casa y el salario de el es utilizado para pagar sus creditos y hacer fretne a cualquier imprevisto, sus hijos son adultos y no estan bajo su reponsabilidad solo una hoven quien esta estudiando la secundaria. Este cliente esta solicitando su 2do credito que sera utilizado para construir un baño y los servicios higienicos dentro de su casa con la intencion de brindar seguridad a su familia para no tener que salir al patio, ya que ellas en algunos dias quedan solas por la noche cuando el esta cumpliendo con su trabajo el que lo desarrolla unos dias de dia y otros por la noche. Su primer credito tambien lo utilizo para mejorar su vivenda, ya que platea que es dificil juntar una cantidad para invertirlo en su casa, que con el credito esta consiente que cada mes despues del pago tiene que pagar la cuota que ya esta establecida.
Additional Information
About AFODENIC
This loan is administered by AFODENIC, La Asociación para el Fomento al Desarrollo Nicaragua, a Kiva Field Partner based in Managua, Nicaragua. Founded in 1999, AFODENIC was created to promote the socio-economic and cultural development of sectors that are excluded from commercial banking. Integrating economic and human resources, AFODENIC offers affordable and adaptable financial services aimed at strengthening the family unit of their clients, who include students, producers, and micro- and small entrepreneurs from rural and urban areas. AFODENIC is a socially responsible institution engaged in society and making a positive impact on its professional partners and communities.
Supporting a borrower through AFODENIC contributes to the pursuit of innovation in mitigating poverty in Nicaragua. Visit
AFODENIC's partner page
for more information.
About Nicaragua
Average annual income
View loans »
Nicaragua Loans Fundraising
Funds lent in using Kiva
Nicaragua Cordobas (NIO) = $1 USD
Success!! The loan was 100% repaid
A loan of $350 helped Agustin to build a bathroom and sanitary services.
Find a Loan
Repayment Term
13 months
(Additional Information)
Repayment Schedule
Jan 21, 2009
Feb 1, 2009
Currency Exchange Loss:
Nov 15, 2009


text:
Dr. Jason Berkowitz
Medical Director
Dr. Jason Berkowitz
Medical Director
New to VCA?Try a Free First Exam
In addition to the traditional services you'd expect at an animal hospital, we also have many speciialized services.
We perform both routine and advanced surgical procedures.
We have availability of internal medicine specialists to perform ultrasounds and consult on medical cases.
We have advance diagnostic and monitoring equipement such as EKG, Ultrasound and Digital Radiography.
Dr. Zimra Gordon now offers house calls. Please speak with a receptionist for details and to set up an appointment.
We have a large full service boarding facility with dog runs and kitty condos. You can add special ammenities such as leash walks and spa packages to customize your pet's stay. If your pet has special medical requirements call us to discuss the special care we can provide.
If you aren't sure if we offer a specific service please call and ask or stop by to visit our facility.
VCA Davis Animal Hospital has a diverse staff that is highly skilled in a wide variety of medical interests. We perform medical services ranging from preventative care to geriatric care, critical care, emergency care, internal medicine and advanced surgical procedures. At VCA Davis Animal Hospital, we treat your pets like our own. We making sure their visit is as comfortable and stress-free as possible while we care for them. We are dedicated to becoming your partner in your pets health care, and we are driven to provide the best customer service.
Zimra Gordon graduated with a BA in biology from Wellesley College in 1992. She received her DVM from Tufts University in 1996. After practicing...Read Full Biography
Dr. Shalmalee Kotwal received both her Bachelor of Arts in Economics and Doctor of Veterinary Medicine degrees at the University of Pennsylvania....Read Full Biography
Best Care
Dr. Berkowitz has been taking care of my family (dog & cats) since he was with County Animal Clinic when he moved on to Davis Animal Hospital we followed. We have had first visits, preventive care, senior wellness, grooming over the years. We are very happy with the care he has provided us. Dr. Berkowitz has always discussed our options and the cost of treatments and calls with results of any test done. His staff is exceptional.. WAY TO GO DAVIS KEEP UP THE GOOD WORK
To enroll in VCA CareClub®, call us at
203-327-0300 or request an appointment.
Bring love and laughter into your life by adopting from a local pet shelter. Our Healthy Start Exam gives expert quality care to your newly adopted friend. Now that deserves a smile..Learn More About Pet Adoption
are overweight or obese,* and often
their owners don't realize the danger.
* Association for Pet Obesity Prevention
Join the club. VCA CareClub®.
VCA CareClub® helps pet owners keep their pets as happy and healthy as possible through convenient and affordable monthly payment plans.More About VCA CareClub®


text:
Gym Leaders Are People Too!
View Single Post
February 3rd, 2013 (5:44 AM).
Pokefan for life!! (:
Join Date: Apr 2010
Location: Cincinnati, Ohio
Gender: Female
Nature: Calm
Posts: 175
Its always been this way though...if you ever read the manga, almost everything circles around the gym leaders. They, with the Player fight for a common goal,
Yes, generally. There were quite a few gym leaders who weren't exactly..on your team such as Koga,
Lt. Surge
, Sabrina, and Pryce.
I agree that the gym leaders needed more of a story to them other than what type of pokemon they have or what they supposedly do in their free time, even though they never seem to come out of their gym leaving me to guess that they sleep and relieve themselves in it as well. I really like how they had the gym leaders actually take part in what was going on. It added more realism to the game that should have been there in the first place.
Friend Code: 5171 - 9762 - 4892
Message me, let's exchange codes! (:
"Peace under an illusion is not true peace. It's only meaningful if the real world manages to accomplish it." - Gaara ♥
75% of Pokemon gamers use cheats and specially made codes to make their pokemon battle-worthy. If you are one of the 25% percent that level their Pokemon up legally,
put this in your signature
View Public Profile
Send a private message to Brittani
Find all posts by Brittani
Find threads started by Brittani


text:
Lofty Perch is a global leader in providing cyber security services and technology for mission critical information architectures. With a core focus on SCADA anMore
$5 mil. - $10 mil.in Revenue
20 - 50EmployeesContact people at this company
it security managementMore
Custom Software & Technical ConsultingSoftwareMore
15-505 Hood RoadMarkhamOntarioL3R 5V6Canadaview map
(908) 489-2828
ProPub_Iteration_NT.411[05] SEIDXWK-23


text: Influenza Influenza, also known as the flu, is caused by a virus. Review Date: 1/25/2013 Reviewed By: Harvey Simon, MD, Editor-in-Chief, Associate Professor of Medicine, Harvard Medical School; Senior Physician, Massachusetts General Hospital. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M. content is best viewed in IE9 or above, Firefox and Google Chrome browser.


text:
See All Contributors »
So....when Dan hired Cotton from his short gig at NU, how many of you knew that under Barney's leadership that rushing yards and yards per carry declined under his tenure? That was after he was hired by NU when Solich cleaned house and fired his coordinators and brought in Bo & Barney b/c of poor performance by those units under previous coordinators. While Bo made progress with the D, the rushing game took a step back under Cotton.
That was the red flag for me when he was hired, but I bought into the hype of the tough guy who was going to make mean men out of our oline...should have trusted the stats.
Kansas State rushing did not light up Nebraska tonight either. Their offenses look abiout the same only we scored more last weeek than the single fieldgoal.
Let Prohm's Posse Ride: Hallice, Brady, Stu, Lard, Naz, Deonte, Monte, Matt, Simeon, Jordan, and Babb.
Forum Rules
All content owned by CycloneFanatic.com - All rights reserved 2005-09. By viewing this website you agree to the Terms of Service, Site Rules and Legal Disclaimer. The words, views, images and opinions expressed or provided by users do not reflect the opinions or views of CycloneFanatic.com or Iowa State University. The names, words, symbols, and graphics representing Iowa State University are trademarks and copyrights of the University protected by the trademark and copyright laws of the United States of America and other countries and are used on this web site under license from the University. Original site design, premise & construction by Jeremy Lind.


text: Home > 25973554-500 SEARS Toilet Model # 25973554-500 SEARS Toilet I Own This Add this model to "My Models" for easy access later. Model #25973554500 was saved to your profile You have reached the maximum number of models that can be added to your list. Please Sign In or Register to have unlimited usage Shop Parts Expert Q&A Browse by section: Shop Parts Expert Q&A 25973554-500 SEARS PAK-A-POTTI IV 0934 SEARS Toilet 1061002 Toilet Search by part name Part name is required Do not enter special characters Part description must be at least 3 characters Find part in diagram SEARS Toilet Model # 25973554-500 Unit Parts 25973554500 0934 1061002 Sears Toilet-Parts


text:
Sign in now to view, license and download this image or contact us to see this image without a watermark. Want to embed this image on a non-commercial website or blog? Learn more.
{{ title }}{{ link.name }}
Horses Pull A Carriage Through The Snowy Landscape Stock PhotoAnimal,Animals In The Wild,Color Image,Day,Herbivorous,High Angle View,Horizontal,Horse,Horsedrawn,Meadow,Medium Group Of Animals,No People,Outdoors,Photography,Rural Scene,Snow,Three Quarter Length,Winter,Working AnimalPhotographer Joel SartoreCollection: National Geographic


text:
Wilwood 180-0055 - Wilwood Brake Cotter Pins
Representative Image
Product images may differ from actual product appearance.
Wilwood Brake Cotter Pins
Wilwood Brake Cotter Pins are designed to replace missing, damaged or worn cotter pins that retain the brake pads to the calipers in Wilwood brake systems. They are manufactured from high quality material and sold ten to a package.
Wilwood 180-0055
Brake Hardware Component Type
Cotter pin
Brake Type
Disc brake
Sold as a set of 10
Manufacturer's Part Number: