text:
|Publication number
|Publication type
|Application number
|Publication date
|Sep 21, 1976
|Filing date
|Jan 18, 1974
|Priority date
|Jan 25, 1973
|Also published as
|Publication number
|Matti Antero Reunanen
|Original Assignee
|Matti Antero Reunanen
|Export Citation
|BiBTeX, EndNote, RefMan
|Non-Patent Citations (1), Referenced by (35), Classifications (15)
|External Links: USPTO, USPTO Assignment, Espacenet
The object of the present invention is a method for the radioimmunoassay of small molecules, such as peptide hormones.
In a radioimmunoassay (RIA) the quantity of a component is determined by adding to a sample the radioactive form of the same substance and the antibody of the substance to be studied. Hence, the component subject to investigation and the added radioactive substance react with the antibody, whereby the higher the proportion of the complex that is radioactive, the lower is the concentration of the studied substance in the sample. This results from the fact that so little of the antibody has been added that all of the substance to be studied and of its radioactive form (antigen) cannot react, for which reason the radioactive and the non-radioactive form compete with each other. By measuring the radioactivity of the complex or of the free form or of both, it is possible to calculate the quantity of the component to be studied in the sample.
The most difficult step of work in radioimmunoassays is the separation of the complex and the free antigen from each other with a sufficiently high precision by means of methods suitable for mass working. There are several techniques in use, depending on the antigen and the operator. A brief summary will be given of these methods of separation:
1. Electrophoresis requires a lot of active working contribution and the sample size is limited (maximum limit 200 μl).
2. Gel filtering requires a lot of active work and time.
3. Non-specific precipitation by means of protein precipitants also encloses free antigen inside the precipitate and requires several washing steps.
4. Immunoprecipitation comprises precipitating of the complex by means of an antibody of the antibody. The precipitate produced is difficult to handle carefully enough, i.e. it can be lost with the washing liquids.
5. By means of adsorption onto a solid phase it is possible to remove the unbound hormone out of the sample and to calculate the complex retained in the liquid phase.
6. The antibody in the solid phase is allowed to react with the antigen, and the free component is washed off.
Among the listed methods, the last two listed are becoming increasingly used. They, however, involve certain limitations. For example, in adsorption onto a solid phase the total protein content of the mixture is critical and must be standardized precisely. The methods also require 2 to 3 precise steps of dosage. Moreover, when hormone contents are measured when determining reasons for disturbed states of metabolism, it is often necessary to choose different separation methods for different hormones. There are no standard methods, and for this reason clinical-chemical laboratories must have high and wide-range specialist knowledge.
When radioimmunological methods become more common in routine use, it becomes more and more important to utilize a method that is simpler and that can be applied to as many hormones as possible. The present invention is intended to meet this need. The method in accordance with the present invention is simple for the operator and it is economical and flexible. Most of the work has been transferred to be done in long series at commercial companies, and only such steps which are absolutely necessary are carried out at the operating laboratories.
According to the method in accordance with the invention, the large-molecule antibody of the small-molecule antigen to be determined is placed in a narrow chamber formed between dialysis membranes in a reaction vessel in order to obtain rapid equilibrium, and a predetermined quantity of the radioactive form of the antigen, the sample and the non-radioactive form of the antigen are added into the reaction tank outside the dialysis bag. Incubation then takes place, and the antigen of the sample and the radioactive antigen freely pass through the membrane and partly react with the antibody thus forming a complex that does not pass through the membranes of the bag, and hereafter washing is carried out. The washing liquids are changed and the unreacted antigen freely passes through the membranes and is removed together with the washing liquids, whereby it is possible, by measuring the radioactivity of the complex remaining between the membranes, to determine the antigen-content of the sample in a way known.
According to the method in accordance with the invention, the antibody is pre-measured in dialysis bags, preferably as absorbed into some porous sheet-shaped material, and the radioactive antigen is pre-measured outside the bag, preferably on the bottom of the reaction vessel. The operator need only dose the patient's serum or plasma in the reaction vessel and to take the tanks into the reaction incubator and washing and calculation. Only the dosage of the plasma requires precision and individual handling of the samples, whereas the other steps are only transfer operations.
The invention will be described below in detail as being applied to peptide hormone determination. The method is, however, also suitable for the determination of other small-molecule substances, such as steroid hormones and drugs.
FIG. 1 shows the reaction vessel and dialysis bag as a longitudinal section and FIG. 2 as a cross section.
FIG. 3 shows the reaction vessel with its contents in a cassette at the incubation stage and FIG. 4 at the washing stage.
Referring now to the drawings in detail, the method works in peptide hormone determination as follows:
In the reaction vessel 1, in a space sealed by the cover 2, as absorbed in a porous sheet (e.g. cellulose acetate) 3 and dried, between dialysis membranes (e.g. of cellophane) 4 sealed by an adhesive seam 5, there is the antibody and on the bottom of the vessel 1 the radioactive form 6 of the antigen. The operator doses the plasma of the patient to be examined or a dilute of the plasma into the vessel 1 so that the liquid level 7 is above the top limit of the antibody sheet 3. Hence, liquid penetrates through the membranes 4 and the sheet 3 becomes wet. Since the hormone has a relatively small molecule size, it can pass through the membranes 4 to react with the antibody in the sheet 3, and in the liquid chamber 8 outside the dialysis bag the hormone content is reduced in proportion to the quantity of the hormone bound. At this incubation stage the reaction vessels 1 are with their mouths 9 upwards in the spaces 11 in the cassette 10, and the cassette is on a swaying base so that when the dialysis bag is moved by the force of gravitation to and fro in the vessel 1, liquid flows alternatingly from the chamber 12 into the chamber 13 and vice versa thus producing an efficient agitation in the liquid space 8 and a faster equilibrium. After completed incubation the cassette 10 with its contents is turned 90� so that the mouths 9 of the vessels 1 become directed towards the side, and water is introduced into the cassette container by pulsating so that the water alternatingly fills the vessels 1 and these are alternatingly emptied, an efficient rinsing being produced in this way. The free antigen adhered to the sheets 3 is also dialysed off the sheets, and the dialysis bags can be transferred to the counter.
The dialysis bags with their contents and the reaction vessel with their active hormones are preferably manufactured as one unit, so that the operator will only have to carry out the dosage of the patient's sample. For each species of hormone preferably a tank-bag combination of its own is used.
The following insulin determination is described as a second example of how the method is carried out in detail.
Commercial reagents are suitable or the reagents can be prepared in the laboratory. The antiserum containing the insulin antibody is obtained by immunizing Guinea pigs by several injections of pure insulin. As radioactive insulin, radio-iodinated insulin I-125 is used. Each reagent is closed in 25 μl of a buffer containing per liter of water: 40 mmoles phosphate buffer (NaH2 PO4 and Na2 HPO4), pH 7,4; 5 g cow plasma albumin; 30 mmoles EDTA; and 0,6 mmoles thiomersalate. For the assay three sets of vessels are required: vessels for the actual samples, control vessels and standard vessels.
To the sample vessel is introduced an antiserum dilution dosed on 15 � 15 mm cellulose acetate sheets (3) which after water evaporation are closed between Cellophane dialysis membranes (4). The appropriate dilution is determined in advance by means of an antiserum dilution series such that the dilution that takes up from 50 to 60 % of the radioactive insulin to be dosed. 20 pg of the above mentioned insulin I-125 is dosed to the bottom of the 25�20�2,5 mm reaction vessel (I).
The control vessels are made ready in the same manner except that instead of diluted serum from immunized Guinea pigs it was used serum from unimmunized Guinea pigs in the same dilution ratio and furthermore it is dosed to the bottom of the vessel (6) 100 μl of human serum out of which the insulin has been separated by absorbing to active charcoal. The standard vessels differ from the sample vessels in that it is dosed to them as to the control vessels 100 μl of human serum treated with active charcoal, and furthermore it is introduced to the bottom of vessel (6) non-radioactive insulin dosed according to the following geometric series: 0, 5, 10, 20, 40, 80, 160 and 320 pg.
All the above mentioned reagents are introduced to the vessels as dry and vessels are made ready in great members at a time.
By clinical determinations out of the prepared vessels two sample vessels, two control vessels and one standard series per patient are chosen. 100 μl serum from the patient is introduced to the sample vessels; 100 μl water is introduced to the control and standard series vessels; 900 μl of the above mentioned buffer containing additionally 9 g NaCl per liter is introduced to all the vessels.
Thereafter follows the steps of incubation and washing. The incubation time is 16 hours and the washing time 6 hours. Then, upon completion of the washing step, the radioactivity is counted by means of a gamma counter. The radioactivity of the control vessels shows a binding that is not specific and undependent upon the antibody, and it has to be substracted from all the results. A standard curve is drawn according the results of the standard series and from this curve the concentration of the samples can be obtained in known manner.
|kabat, Structural Concepts in Immunology and Immunochemistry, Holt, Reinhart and Winston, Inc., New York, 1968, pp. 67-81.
|Citing Patent
|Filing date
|Publication date
|Nov 2, 1979
|Jan 19, 1982
|Corning Glass Works
|Radiometric assay of dialysates
|Oct 13, 1981
|May 1, 1984
|Liotta Lance A
|Enzyme immunoassay with two-zoned device having bound antigens
|Jun 23, 1987
|Aug 22, 1989
|The Research Foundation Of State University Of New York
|Disposable antigen concentrator and detector
|Feb 23, 1983
|Dec 17, 1991
|Bio-Metric Systems, Inc.
|Quantitative analysis apparatus and method
|Jul 15, 1993
|Apr 22, 1997
|Unilever Patent Holdings B.V.
|Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
|Jun 1, 1992
|Aug 5, 1997
|Bio-Metric Systems, Inc.
|Chemical analysis apparatus and method
|Sep 15, 1994
|Aug 12, 1997
|Unilever Patent Holdings B.V.
|Test device for detecting analytes in biological samples
|Aug 16, 1996
|Apr 7, 1998
|Landry; Donald
|Detection of organic compounds through regulation of antibody-catalyzed reactions
|Mar 31, 1993
|Mar 2, 1999
|Smithkline Diagnostics, Inc.
|Immunochromatographic assay device
|Feb 10, 1994
|Dec 7, 1999
|Beckman Coulter, Inc.
|Opposable-element assay devices, kits, and methods employing them
|Jun 5, 1995
|Jan 25, 2000
|Beckman Coulter, Inc.
|Assay device
|Jun 1, 1992
|Feb 1, 2000
|Surmodics, Inc.
|Chemical analysis apparatus and method
|Sep 23, 1998
|Nov 28, 2000
|The Regents Of The University Of California
|Simultaneous measurement of free triiodothyronine and free thyroxine by equilibrium dialysis and immunoassay
|May 29, 1991
|Jan 2, 2001
|Beckman Coulter, Inc.
|Multiple component chromatographic assay device
|Jun 7, 1995
|Feb 13, 2001
|Conopco Inc.
|Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
|Jun 7, 1995
|May 8, 2001
|Conopco Inc.
|Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
|Jun 9, 1997
|Mar 5, 2002
|Unilever Patent Holdings B.V.
|Analytical test device for imuno assays and methods of using same
|Feb 28, 2001
|Nov 16, 2004
|Inverness Medical Switzerland Gmbh
|Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
|Feb 12, 2001
|Sep 19, 2006
|Inverness Medical Switzerland Gmbh
|Sep 4, 2001
|Jul 3, 2007
|Inverness Medical Switzerland Gmbh
|Dec 23, 2002
|Jun 10, 2008
|Inverness Medical Switzerland Gmbh
|Dec 23, 2002
|Aug 5, 2008
|Inverness Medical Switzerland Gmbh
|Aug 3, 2010
|Gen-Probe Incorporated
|Instruments and methods for exposing a receptacle to multiple thermal zones
|Aug 24, 2010
|Gen-Probe Incorporated
|Instruments and methods for mixing the contents of a detection chamber
|Dec 12, 2008
|Nov 1, 2011
|Gen-Probe Incorporated
|Gravity-assisted mixing methods
|Nov 8, 2011
|Gen-Probe Incorporated
|Gravity-assisted mixing methods
|Jul 13, 2011
|Jul 9, 2013
|Gen-Probe Incorporated
|Instruments and methods for mixing the contents of a detection chamber
|Mar 7, 2012
|Jul 23, 2013
|Gen-Probe Incorporated
|Instruments and methods for mixing the contents of a detection chamber
|Dec 12, 2008
|May 27, 2014
|Gen-Probe Incorporated
|Methods of concentrating an analyte
|Dec 12, 2008
|Jul 1, 2014
|Gen-Probe Incorporated
|Methods and instruments for processing a sample in a multi-chambered receptacle
|Jun 24, 2013
|Jul 22, 2014
|Gen-Probe Incorporated
|Methods for manipulating liquid substances in multi-chambered receptacles
|Jul 8, 2011
|Sep 9, 2014
|Gen-Probe Incorporated
|Methods for manipulating liquid substances in multi-chambered receptacles
|Oct 1, 2012
|Jul 23, 2014
|Partitioned reaction vessel
|Aug 17, 1981
|Mar 10, 1982
|Gambro Lundia AB
|A method for the recovery of a peptide-containing compound, and an apparatus for the realization of the method
|Oct 1, 2012
|Apr 4, 2013
|Ge Healthcare Limited
|Partitioned reaction vessels
|U.S. Classification
|436/535, 436/817, 436/530, 436/807, 436/542, 436/804, 436/536
|International Classification
|Cooperative Classification
|European Classification


text:
Meek Mill ft. Nicki Minaj, Fabolous & French Montana - Its Me (I Be on That)
Posted 2 years ago
Tags: Meek Mill , Hitmaker , Street Banger
Fresh off lending his flow to Yo Gotti's F**k You, Meek Mill steps back into the spotlight with It's Me (I Be on That), a brand new single off his next mixtape. Though this whip-ready selection is, as the title suggests, a monument to the MMG signee's love of self, Meek leaves enough room for a trio of high-profile guests to jump "on it" beside him; French Montana, Nicki Minaj and Fabolous join the Philly repper over an uncredited beatsmith's eerie, bass-booming street boardwork. For this braggadocious cut, previously-featured single Levels and much more, cop the highly-anticipated Dreamchasers 3 street album when it drops digitally on Sunday, September 29.
Meek Mill Nicki Minaj Fabolous French Montana HitmakerStreet Banger
Written by richard
Posted 2 years ago
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Posted on Sep 29, 2013
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Jason Fabok's 10 Favorite "Justice League" Moments
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Right now in Hollywood, a small army is working on video game movies, hoping to to crack the code and make the elusive good adaptation. Seth Lochhead is now among the ranks. According to The Hollywood Reporter, the writer of Hanna has just signed on to pen a script based on the Sony Playstation 2 game Shadow of the Colossus.
The project was announced in May with Josh Trank (Chronicle) set to direct. he's overseeing the writing process, which began with a script by Justin Marks (Street Fighter: The Legend of Chun-Li). In the video game you play Wander, a dude riding around on Argo in search of 16 giants called colossi. He has to fight and defeat each colossus in order to save a girl named Mono.
Trank is one of the busiest young directors in the business: In addition to this film, he's also working on Fox's Fantastic Four reboot and has also been mentioned in connection with a Venom movie and an adaptation of The Red Star.
As I played this game I felt like I was playing a Miyazaki film.
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Whitford Doubles UK Space With New, Larger Facility
Tuesday November 6th, 2012 - 11:40AM
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Whitford, manufacturer of fluoropolymer non-stick coatings, has moved its UK facility to a larger property to accommodate recent growth as well as provide room for continued expansion.
"With the additional space and new systems we have in place, our efficiency should increase significantly. It's a great step forward for us," said Martin Garnett, managing director of Whitford Ltd.
Located only a few hundred meters from the old facility, the new Whitford building, which is 78,000 square feet is double the size of the size of Whitford's previous facility and features a 70% larger manufacturing space. The laboratory has 90% more space, and the office area has doubled as well.
Whitford has also made significant investments in state-of-the-art equipment in the new laboratory and quality-control areas. Additionally, extra space in the manufacturing area allows for improved efficiency, influenced by Lean Manufacturing Principles and a Kaizen culture, the company said. Updated stock-control systems have been developed to meet expanding customer delivery expectations.
"The new facility reflects the good work Whitford Ltd. has done and continues to do. Here's to more of the same!" Dave Willis, founder and president of Whitford, said.
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Bring a buddy.4.54 / 5.00 9,281 Views
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Vampire Pixel in the Neon City
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Very funny
Great animation, perfect music and very amusing.
Excellent!!! =D
Oh wow, that was excellent! The characters were SO adorable, and the music added so perfectly to the whimsical mood. I laughed so hard when they missed the plane. I absolutely love artsy flash toons like this. I would have liked for the chase to have lasted a bit longer with a few more wacky antics, though.
tune your guitar next time
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Great animation
Character designs accompanied to such a fitting animations makes this a great flash....and I have to admit those little creatures are kinda cute in their own way LOL great work and extra points to uniqueness....


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Car accident damages utility pole, blocks traffic, in 1500 block of Tennessee Street
I was the driver of the car and I am sorry for what happened. I wish I could correct what happened. But alas it is history and all I can do now is accept the punishment meted out to me.
December 26, 2012 at 12:44 a.m. ( permalink | suggest removal )
Car accident damages utility pole, blocks traffic, in 1500 block of Tennessee Street
I was the driver of the car. I regret what happened and will go to court to pay for and be punished for what I rightfully deserve. I am sorry to the community of Lawrence for the trouble I directly or indirectly caused. I am an international student and may be deported due this incident. I also am grateful that Lawrence and KU provided me a great opportunity to learn and gain a new perspective. I have met great people here and they will always be important to me no matter if I get a chance to stay here and finish my studies or if I get deported. Thank you all. Please accept my deepest apology.
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DPReview Live: Interview with Art Wolfe
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If you missed our two-day live streaming event, you'll soon be able to catch up on the discussions, interviews and panels that took place as part of our collaboration with CreativeLive. We'll be posting more videos in the coming days.
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Yum Brands Inc.
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Angus Binney
Bindor Development Pty Ltd
Geoffrey Binney
Gauntt Earl & Binney LLP


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Heads Up: 1921 Hosts Heatwave! Featuring BLORR, Alexander and DJ Mig This Friday
The 1921 club (1921 S. Federal Highway, Fort Lauderdale) decor might remind some of an opium den, but we're just gonna call the spot a den of social stimulants -- a place where so much is happening that blinking is a highly risky behavior.
Come Friday, April 30, BLORR -- which stands for the self-explanatory Bastard Lovechild of Rock 'n' Roll (as illustrated on the subtle T-shirt design to the right) -- and local rockers who probably don't agree with Karl Marx's pejorative "religion is the opium of the people" comment, Alexander, will both rock the 1921 stage for the Heatwave! Doors are at 9 p.m., and cover is a steal at $5.
Crossfade pal DJ Mig Lauderdale -- worthy of more fawning adjectives than this space can possibly allow -- will cap the night with a set guaranteed to raise everyone's body temperature even further.
If you need directions to 1921, watch our helpful video regarding the topic right here.
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Earth Day: Green ideas you can implement now
April 22 is the day to be kind to the planet and start developing Earth-friendly habits.
Apr 21, 2009
April 22 is Earth Day, and groups across the world will participate in environmental awareness activities. Whether you're a green expert or someone who consumes enough energy to power a small town, there's plenty you can do to pitch in. From purchasing compact fluorescent light bulbs to installing solar panels at your hospital, every little bit counts. Click here to visit the Earth Day Network Web site or see the related links below for green inspiration.
Hot topics on dvm360
Is the gold standard the old standard?
May 10, 2016
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May 01, 2016
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Mar 17, 2016


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May 27, 20163:21 AM ET
HIROSHIMA, Japan (AP) — The Latest on U.S. President Barack Obama's visit to Hiroshima, Japan (all times local):
May 27, 20161:48 AM ET
HIROSHIMA, Japan (AP) — Visitors to the Hiroshima Peace Memorial Park on Friday had this to say ahead of U.S. President Barack Obama's visit later in the day. Obama is the first sitting U.S. president to come to Hiroshima, a city devastated by a U.S.-dropped atomic bomb at the end of World War II.
May 27, 20162:45 AM ET
SHANGHAI (AP) — In 2011, a respected anti-counterfeiting coalition in Washington escalated its fight against the Chinese e-commerce giant Alibaba, saying its websites served as a 24-hour market "for counterfeiters and pirates" and should be blacklisted.
May 27, 20163:31 AM ET
COSTA MESA, Calif. (AP) — Brendan De Regla drove three hours and waited in line for half a day to see Donald Trump speak at a rally in Southern California.
May 27, 20163:22 AM ET
WASHINGTON (AP) — Since her use of a private email server was made public last year, Democratic presidential candidate Hillary Clinton has insisted she turned over all work-related emails to the State Department to be released to the public.
May 27, 20161:15 AM ET
OAKLAND, Calif. (AP) — "We ain't going home! We're not going home!" Stephen Curry screamed at the top of his lungs.
May 27, 20162:19 AM ET
PITTSBURGH (AP) — During his first day on the job in mid-December, Mike Sullivan looked around the Pittsburgh Penguins' dressing room and saw a couple of MVPs, a handful of All-Stars and millionaires in abundance.
May 27, 20162:32 AM ET
PARIS (AP) — Two rounds of French Open tennis haven't come close to turning Marco Trungelliti into a millionaire.
May 27, 20162:22 AM ET
A look at what's happening all around the majors today:
May 26, 201611:33 PM ET
Mike D'Antoni is taking his "Seven Seconds or Less" offense to Houston, where James Harden is waiting to give his new coach the kind of weapon that could be a perfect fit for his system.


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26th May 2016
Gold fell by 4%, the lowest level in seven-weeks on Wednesday, as the strong data on New U.S. Single-family Home Sales in April supported the view that the economy may be strong enough for the Fed to hike interest rates soon.
Dollar Stands Tall and Gold Loses Luster
25th May 2016
The USD surged to its highest level in eight-weeks vs. the EUR on Tuesday, amid expectations that the U.S. Federal Reserve could raise interest rates soon. On the other hand, global stock indices rallied, led by shares of financial companies, banks and technology.
Fed Members Insist On Raising Rates
24th May 2016
San Francisco Fed President John Williams said, "The Federal Reserve is on track to raise interest rates in June or July despite risks such as The United Kingdom European Union membership referendum, and will continue with even more hikes next year given U.S. economic strength."


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Jorja Smith Unveils Visuals for Breakthrough Single 'Blue Lights'
Wednesday, March 2, 2016 - 10:55
Jorja Smith dropped her enchanting debut single 'Blue Lights' and from there on, her name was on everybody's lips. Receiving co-signs from the likes of Skrillex and Stormzy and with almost half a million plays on Soundcloud, the 18 year old is definitely making a killer impression within the UK music scene.Back in January,
Speaking on the idea behind the Drew Cox directed visuals, the Walsall native chose to depict a black male who had a choice between three different avenues to take, however "this man is fighting with himself and the perception that society have given him". With such an enigmatic concept, this leaves plenty of room for interpretation with the audience.
You can catch Jorja Smith performing on the main stage at Wildlife Festval this summer on Sunday 12th June! Click here to grab yourself a ticket.
Meanwhile, make sure you check out the visuals for 'Blue Lights' below:
Words: Sarah Malik
Online Edit: Ra'ed Khan
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Blogs Liberty and Power The LockeSmith Institute - new blogAug 29, 2007 6:10 pm
The LockeSmith Institute - new blog
The LockeSmith Institute, which seeks to promote the scholarship of classical liberalism through the exploration of the principles of individualism, private property and the free market, the rule of law, and social toleration, now has a new bag - blog, that is.
Visit The LockeSmith Blog.
Visit The LockeSmith Blog.
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- This Man Spent 25 Years Documenting Every Day of Hitler's Life
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- What About Us, Nagasaki Asks, as Obama's Hiroshima Trip Nears
- Korean Survivors of Atomic Bombs Renew Fight for Recognition, and Apology
- African American museum's fundraising touches deep history among donors


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Mashup: Top20Hotness
Aggregates and visualizes trends on Google, Yahoo and Amazon. It is also a customizable search engine that can be added to your toolbar. Once an account is created, users can maintain a top 20 list and add web clips to their scrapbooks.
Followers (1)
Mashups using the same API (268)
Website analytics and classification mashup Lionyzer analyzes content, environment, current popularity and other parameters, assigns a grade and provides helpful advice to improve a site.
Protect.ly is a software-as-aservice that aims to help developers, designers, and teams to protect digital products from pirates such as site templates, eBooks, plugins, and extensions with the goal...
News stories for everything from the latest current business news, tech news, health news, advertising news, and corporate blogs. All powered by nobosh's algorithms.
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Yahoo BOSS Search API Goes Commercial
Innovation in web service APIs is not always technical, sometimes it's about money. Such is the case with Yahoo's announcement that later this year they will begin charging for usage of BOSS (Build your Own Search Service), their search web service for developers. Given that search revenue is typically ad-driven, and that advertising doesn't typically mesh with APIs, this has meant that search APIs have been one of the most challenging classes of APIs for providers to monetize. So it's notable to see how Yahoo has chosen to tackle this: via a 'utility' pricing model, somewhat akin to how infrastructure services like Amazon Web Services charge by usage.
Shuffler.fm Turns Bloggers Into DJs
Shuffler.fm is a web based music magazine that allows users to browse music on the web through music sites and blogs. It allows them to discover new music and keep an eye on current trends, with the help of those in the know.
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System Integration Channel
Triple output micromodule regulator
Linear Technology Corporation's LTM4634 regulates common intermediate power buses such as 12 V, 5 V and 3.3 V in instrumentation with its combination of wide output voltage range, a thermally efficient package, tight regulation... » more
Analog to digital; now, digital back to analog
Technology Update: Returning to analog instrumentation and controls might offer more than nostalgic benefits. Higher reliability and fewer cyber security risks could result. Should some things that are new be old again? Look at... » more
Information Control Channel
Automation budgets: more than automation
Think Again: When considering an automation, controls, or instrumentation project, look beyond the price of equipment, software, and networks toward many extended, often unquantified, benefits. » more
Does your supplier selection process include these items?
With leaner engineering departments and more options to choose from, selecting the right solution is an ever growing challenge. The selection process should remove bias, avoid conflict, and deliver a fact-based result with these... » more
Process Control Channel
Secrets of effective HMI design
Creating an interface that's effective and efficient, and maybe it will look nice too. » more
Industrial Efficiency - Debunking the Myths: Putting time, money into pumps will pay off
In this third installment of this series, Jack Creamer addresses three common myths regarding the impact of pumps in a facility, energy efficiency, and ROI. » more
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Festo gets Hannover Messe hopping
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An OSHA/legal definition of de minimis and a clearer understanding of – What do employees need to know? will certainly help all companies unfold LOTO for full compliance.
Unfolding Lockout/Tagout (LOTO)!
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Pictured: The Mr. Tinker Bell's Untamed Ride attraction at midday
Mr. Tinker Bell has a reputation as the worst driver in Fantasyland. On this attraction, you act as if you are him, shattering Tinker Bell Hall, upsetting the countryside, being run over by a train, and even going straight to Narnia!
Please don't try Pirate Mode
© copyright 2011–2016
A Pants Aflame production


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I haven't aborted any of my games today so why the punishment
I know, its ridiculous, its telling me the same thing, I liked it better when people aborted games and people didnt get punished because their punishing me for doing nothing...
this same thing happen to me- I don't have a membership so I have little rite to complain but Ive been playing on this. site for yearsan always talk highly of it to friends
No comments not worth the debate
Vintage circa 1890s British Chess Company Set used at Hastings Chess Congress
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Leaving their footprints on the hearts and souls of patients in hospitals and care centers in the Manteca community is what "Paws for Friends" is all about.
High school students are being sought to apply for five vacancies on the Manteca Youth Advisory Commission.
Just who - or what - is depleting the ranks of salmon and steelhead in the Stanislaus River as well as the Delta?
By GLENN KAHL
Surveillance cameras costing $65,000 may be installed at the new Manteca transit station when construction is completed in 2012.
Manteca's oldest community recreation complex - Lincoln Park - is about to get another upgrade.
Half Moon Bay's bold and dubious claim in the 1970s that it is the Pumpkin Capital of the World has helped generate around $1 million for Manteca non-profits.
The chances of pedestrians taking deadly shortcuts across Union Pacific Railroad's main rail line through Manteca between Main Street and Industrial Park Drive has been greatly reduced.
August was the best month in three years for job growth for Manteca residents as 900 people found employment.
The quick action of a Manteca Police officer back in early February, that ended in the arrest of two armed robbery suspects after a foot pursuit, is being lauded by the Manteca City Council.
Manteca's longest running celebration - the annual St. Anthony's Harvest Festival - takes place today and Sunday at the church grounds at Fremont and Sutter streets.
Central Valley Realtors are using their golfing talents to raise money for the South San Joaquin County Food Bank and Turkeys R Us for the upcoming holidays.
LATHROP – A half sales tax could generate $1 million a year to help hire additional firefighters and police for the City of Lathrop.
Armando Cordoba was 3 ½ klicks behind enemy lines on a recon mission in Cambodia when he realized that he was in trouble.
Hundreds of families – including single moms with children – have been kept from living permanently on the streets since the HOPE Family Shelters first opened 19 years ago.
Page 503 of 875
ECHO SUMMIT - A nearly average spring snowpack in the Sierra Nevada will likely prolong tough water conservation measures in drought-stricken California - although the restrictions could ...
Weston Ranch High School senior Mariz Dano learned two important life lessons this year.
Manteca Unified has failed to seek the inclusion of a number of new Manteca housing projects into a Mello-Roos district that's considered crucial to ...
The Second Harvest Food Bank is looking for a dozen good citizens to volunteer in its "Mobile Fresh" food distribution system two days a month ...
If you ask Joe Brocchini what he likes the most about Manteca, you might want to pull up a chair.
The biggest spring shindig in South San Joaquin County is getting bigger.
Diane Lazard is Lathrop's newest planning commissioner.
The "over-the- hill" expression can have so many connotations.
It was a tale of two halves Tuesday with Manteca winning the first half and Sierra the second but neither won the game as the ...
Editor's note: This is part of an occasional series on rivers, lakes, reservoirs, the Delta and the weather that play a key role in ...
Petitioners for a "Change in the Point of Diversion" permit before the California State Water Resources Control Board, on Monday requested a second delay in ...
Winter is historically the slow month for home building.
It's a business that definitely has a stigma attached.
If I drink any more water I'm going to explode.
ISLAMABAD (AP) - A bombing on Easter Sunday killed 65 people in a park in the eastern city of Lahore that was crowded with Christians, including ...
Page 17 of 18
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Virginia Finishes with Seven Picks in 2015 MLB Draft
La Prise, Towns, Pinero selected Wednesday
Return Engagement in Omaha Awaits Surging 'Hoos
By Jeff White (email@example.com)
Virginia Defeats Seton Hall, 4-1, Improves to 9-0
Three UVa pitchers limit Pirates to five hits
Virginia Baseball Will Play for National Championship on Wednesday
Cavaliers even the series against Vanderbilt with 7-2 victory
Virginia Baseball Advances to CWS Finals
Cavaliers defeat Ole Miss 4-1 to advance to finals for first time in program history
Virginia vs. Vanderbilt- College World Series Game 2
Virginia vs. Vanderbilt- College World Series Game 2
Virginia Baseball: 2014 Season in Photos
Relive all of the excitement by browsing some of the best images from the run to the College World Series.
Virginia v. Ole Miss 6/21/14
Virginia beats Ole Miss 4-1 on 6/21/14
Baseball vs. Clemson (by Matt Riley)
Baseball vs. Clemson (by Matt Riley)
Baseball vs. East Carolina (By Kelsey Grant)
Baseball vs. East Carolina 2/23/14
• Selected by Toronto Blue Jays in 19th round of 2015 MLB Draft
• Played in just four games in February while battling injury
• Missed remainder of season after undergoing hip surgery on April 1
• Played in 50 games, including 46 starts (23 at third base, 22 at DH, one at second base)
• Named to Charlottesville Regional All-Tournament Team
• Batted .300 (15-for-50) and started all 12 games in NCAA tournament; was 7-for-13 in regional
• Had four hits in CWS Finals series against Vanderbilt
• Was 3-for-10 in ACC tournament
• Went 3-for-11 with RBI in Georgia Tech series
• Was 3-for-8 in FSU series; hit first career home run in Game 1
• Was 4-for-11 in UNC series
• Cooled off in Clemson series after batting .556 (15-for-27) in previous 10 games
• Was 3-for-3 and reached base in all five plate appearances at James Madison (4/10)
• Started at third and went 2-for-4 with RBI vs. ECU (2/23)
• Had two hits, including RBI double, off bench at William & Mary (2/19)
• Played in 19 games, appearing in nine as pinch hitter
• Earned seven starts, including two in ACC play: May 12 against Duke and May 18 at North Carolina
• Started ACC tournament game against Georgia Tech and had sac fly (5/23)
• Hit two-run triple in 11th inning in win at UNC (5/18)
• Had pinch-hit single, scored run against VCU (5/14)
• Was 1-for-6 in Duke series
• Went 1-for-4 as DH against JMU (4/24)
• Named to All-Southeastern PA Baseball first team in 2012
• Selected as 2012 Bicentennial Athletic League MVP
• Was two-time first-team all-league selection
• Named 2012 team MVP and earned school's 2011 Barry M. Henley Award for baseball
• Earned 2012 Devon Prep Alumni Award for Athletics
• Holds the Devon Prep single-season stolen base, RBI and home run records
• Earned All-Main Line and Daily Local News All-Area first-team honors in 2011
• Coached by Mark Aquilante at Devon Prep
• Also played two years of soccer (center midfield) and three years of basketball (point guard)
• Was a first-team All-Bicentennial Athletic League selection in basketball
• Member of National Honor Society; earned English Award and School Loyalty Award
• Parents are David and Marie La Prise
• Has one sister, Caroline
• Father played soccer at Maine
UVA Athletics Information
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Mihaljevic's Star Continues to Rise at UVATrack & Field, Cross Country5/24/16In junior Filip Mihaljevic, Virginia's track & field team has one of the nation's elite shot putters and discus throwers.Power Surge Contributing to Cavaliers' SuccessBaseball5/21/16Timely home runs helped No. 8 Virginia win the first two games of its series with ACC rival Virginia Tech at Davenport Field.Versatile Doherty Delivers AgainBaseball5/20/16On a night when starter Connor Jones struggled, Kevin Doherty pitched four innings of scoreless relief in No. 8 Virginia win over Virginia Tech at Davenport Field.
Jeff White
Director of News Content
A 1985 graduate of UVA, White worked at the Richmond Times-Dispatch until July 2009. He was honored six times as the state's Sportswriter of the Year.
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The American Academy of Pediatrics recommends breastfeeding for at least 12 months. The longer babies are breastfed, the greater the health effects for both mom and baby. Breastfeeding is good for your employer too - it reduces parent absence for baby's illnesses. Breastfeeding reduces cases of:
• Postpartum bleeding
• Ovarian cancer
• Premenopausal breast cancer
• Obesity (breastfeeding women return to pre-pregnancy weight quicker)
• Broken bones from osteoporosis
Fitting Breast Shields: Determining the Correct Breast Shield Size
Human Milk Microbiome
Modern parenting is beautiful, messy, exhausting and wonderful - And while information is great, real-world wisdom is even better.
2013 Breastfeeding Hall of Excellence Inductees Announced


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It only takes a minute to get started. Fill out our simple sign up form and login to the website.
This step is discretionary but will greatly boost your chances of your profile being viewed by others. Type a little about yourself, your interests and upload any nice photographs of yourself.
Utilise our website's advanced search to pinpoint members who match your desired criteria. Or just look through listings and pinpoint singles that take your fancy.
Located someone who you find interesting? Drop them a line or just a wink and see if they're interested. With a little luck you'll be on your way to an amazing adventure.
It only takes a few minutes


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Lyrics Depot is your source of lyrics to Fruite Bats by Smog. Please check back for more Smog lyrics.
Fruite Bats Lyrics
Artist: Smog
Album: Sewn to the Sky
A symphony of fruite bats
Wrapping on my window pane
I ask them so gently
To go away
Please go away
A symphony of fruite bats
Wrapping on my window pane
You know your
What you're doing to the eye
Do you have a purpose?
Tapping on my window pane
A symphony of fruite bats
Go away
Please go away
Smog Lyrics
Smog Sewn to the Sky Lyrics
More Smog Music Lyrics:
Smog - Butterflies Drowned in Wine Lyrics
Smog - Cold Discovery Lyrics
Smog - Connections Lyrics
Smog - It's Rough Lyrics
Smog - Limited Capacity Lyrics
Smog - Palimpsest Lyrics
Smog - Renee died 1:45 Lyrics
Smog - Stalled on the Tracks Lyrics


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SparkFun will be closed for Memorial Day (5/30). Orders placed after 2pm MT on Friday (5/27) will process and ship out on Tuesday (5/31).
Member Since: July 27, 2006
Country: United Kingdom
Oxford University, Microsoft Research
Java, C, C#, Matlab, PHP,
tracking, navigation, pattern recognition, machine learning, biology
Have done, thanks
We're using a few of these to log RFID via an Arduino Nano - in most cases this is working great, but a couple of the OpenLogs seem to have fallen into an unresponsive state - no serial response, no LEDs, no reset response. Connections look fine, no apparent damage on board. Any thoughts?
What's the difference in weight with and without the antenna shield?
No public wish lists :(


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Les Contes d'Hoffman - LIVE
The story of one man and the three women he loved and tragically lost, Les Contes d'Hoffman is performed live by the Metropolitan Opera with Joseph Calleja in the title role, Anna Netrebko as Antonia and James Levine at the conductor's podium. Tickets are almost sold out for today's performance in New York, but opera fans in Houston won't have trouble finding a seat in one of several theaters broadcasting the live performance (and they won't have to pay the $295 price tag for premium seats, either - ouch!) Noon. Various theaters, including Edwards Houston Marq*E 23 & IMAX, 7620 Katy Freeway. For information, visit www.fandango.com. $16 to $24.
Sat., Dec. 19, 2009
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Sign up for our weekly guide to events in Houston, and never be bored again. With suggestions for every day of the week, our recommendations will keep you busy on any budget.
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Houston Rockets
TicketsThu., May. 26, 12:00am
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TicketsFri., May. 27, 5:30pm
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Measurement and Modeling of Drop Absorption Time for Various Ink-Receiver Systems
Abstract:An inkjet visualization setup was used to measure the drop absorption time of various ink-receiver systems. The drop absorption time is defined as the time required for the receiver to completely absorb the impinging ink drop (i.e., the drop totally penetrates into the receiver and disappears from the receiver surface). The inkjet visualization setup consists of a piezo printhead with drive electronics, an aluminum drum for receiver support, a strobe light, a CCD camera, imaging optics, and image capture system. The drops ejected from the printhead have a volume of about 25 pL and a velocity of about 5 m/s. The receivers used in the measurements include both non-porous and porous receivers. Results indicate that non-porous receivers with swellable polymeric coatings have a much longer drop absorption time (>30 s) than those receivers with porous coatings (∼33.3-100 ms). The difference in drop absorption time between non-porous and porous receivers can be ascribed to the basic difference in the physical mechanisms of ink penetration into the receiver, i.e., diffusion of ink in the polymeric receiver versus capillary flow of ink in the porous receiver. Based on these physical phenomena, simple one-dimensional models have been developed to describe the drop absorption process in the non-porous and porous receivers. The dependence of drop absorption time on the volume of ink drop and physical properties of ink (such as viscosity and surface tension) and receiver (such as diffusion coefficient and porosity) was also derived. Comparison of model results with experimental data will be presented and discussed.
Document Type: Research Article
Publication date: January 1, 2002
For more than 25 years, NIP has been the leading forum for discussion of advances and new directions in non-impact and digital printing technologies. A comprehensive, industry-wide conference, this meeting includes all aspects of the hardware, materials, software, images, and applications associated with digital printing systems, including drop-on-demand ink jet, wide format ink jet, desktop and continuous ink jet, toner-based electrophotographic printers, production digital printing systems, and thermal printing systems, as well as the engineering capability, optimization, and science involved in these fields.
Since 2005, NIP has been held in conjunction with the Digital Fabrication Conference.
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|Filed Under:
|Society & Culture / Men's Interest
|Posts on Regator:
|Posts / Week:
|Archived Since:
|April 29, 2009
Keep your keys from jingling with this elegant EDC from Michael Rahban Design. Made from CNC machined anodized aluminum, it can even hang on your fridge thanks to its neodymium magnets. Choose from black, gunmetal, or silver. Save 15% in The Awesomer Shop.
"Roman coinage? Being wheeled into a sunny spot? Lenses in an hour or less?" HBO shares the outtakes of the Silicon Valley scene where T.J. Miller's insecure douchebag investor character Erlich Bachman meets seasoned CEO Jack Barker...
The happi is a Japanese traditional short coat adorned with bold icons and patterns and usually worn in festivals. Kapital adds a streetwear twist to the happi using cotton fleece with modern prints or upcycled military garments.
Another cool drop from The Awesomer Style collection, these red slip-ons are required wear for an evening of Netflix and whatever else. They feature a comfy and cozy massaging footbed, an anti-abrasion adjustable strap, and a sneaker outsole for outdoor wear.
Welcome to the party, pal! Burger Fiction presents a compilation of scenes in which characters either welcome the audience or other characters to the scene, providing a quick and easy path to exposition.
Mosevic creates its sunglass frames using resin-coated layers of denim, gathered from discarded and damaged jeans. The end result is not only a stunning design, but a great statement on sustainability. Each comes with quality Zeiss polarized lenses.
A fake product that would totally sell millions if it were real, the Bose Shhhh is the creation of Dad Dudes, who envision a gadget which can magically filter out every noise that you find annoying, from kids to coworkers.
Stanley Franks learns that he has a rare condition, in which he can only utter 1500 more words before he dies. Andrew Chaplin's darkly comic short film looks at how Stanley chooses to use his remaining words, after wasting most of them reacting to his condition.
(Flashing lights) CineFix shares its picks of movies whose greatness lay in throwing convention out the window. There are movies that acknowledge the audience, movies that don't have stories, and movies that were made by Andrei Tarkovsky.
Mondo celebrates the 25th anniversary of David Cronenberg's dark sci-fi drama by making its soundtrack available on vinyl for the very first time. The haunting jazz score was composed by Howard Shore, Ornette Coleman and the London Philharmonic Orchestra.
The School of Life talks about the common factors that influence our sense of self-worth. Whatever the cause, it's important to realize that we should accept and love ourselves, and that comparing ourselves to others is pointless.
A record player that streams to Sonos and Airplay devices as well as over Bluetooth. It can even turn your Spotify account into a radio channel by streaming music through the service. The catch? It has no wired output options.
Motor Trend's Head 2 Head compares the world's fastest SUV, the 2017 Bentley Bentayga, with the world's quickest SUV, the 2016 Tesla Model X. It's mostly a sane discussion, except for the silly drag race at 3:31.
A highly customizable trailer for rugged destinations. The Base Camp Trailer is made of steel sheets over a steel tube frame with 15? wheels. Options include a roll out kitchen, storage boxes, a rooftop tent and a heavy duty solar charging system with AC and USB ports.
"She is an it. And it has no rights." Kate Mara plays a "corporate troubleshooter" sent to a remote location to investigate a rapidly evolving genetically engineered being. Also starring Paul Giamatti, and Anya Taylor-Joy (The Witch) as the titular character.
Co-designed by Apartment Therapy founder Maxwell Ryan, Interior Define's Maxwell sofa combines a deep seat, a low-profile height and curved shapes to create a modern take on European sofas. Available with a variety of fabric covers.
"I've gotten to see the world while doing this job. Well, not the world, just the eastern suburbs." A young construction worker talks about the pros and cons of his job in this funny short promo film made for Carpentry Contractors Company.
(PG-13: Language) Chef, restaurateur and reformed party guy Matty Matheson shows us his take on deep fried chicken. You're going to need some pickle brine, buttermilk, spices and one to three days. Oh!
Square Enix borrowed heavily from its hallowed SNES hit Chrono Trigger to make a 90's JRPG for the modern era. I Am Setsuna is about an enchantress who is sent by her villagers to be sacrificed to a monster. Drops 7/19/16 for Windows and PS4.
The earliest known predecessor of the necktie is depicted in Chinese sculptures from 209 BC. But it wasn't widely used until the 1630s, when Croat soldiers brought cravats to France. The tie as we know it today wouldn't come about until the 1920s in New York.


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Air Conditioning and Heating
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Duct Cleaning Atlanta Ga
Is the quality of air in your home less than what it could be? If you haven't had your air ducts professionally cleaned in a while, it might be a lot worse than you think it is. Daffy Ducts offers professional duct cleaning in the Atlanta, GA and surrounding areas. If you'd like to breathe a better quality of air, call Daffy Ducts today at 404-334-3062.
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Looking for a new furnace? Head down to the
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Roofing Company
HYP Construction is your Southern California roofing company. We are licensed, insured, and bonded. We know what it takes to get you the best possible product without all the expense. We make sure that communications are key and keep a clean and organized workspace as this will cut down on time needed and costs for the completion of the job.
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Construction Dictionary
Foundation RebarRebar refers to steel rods, which are put in footings and grade beams in a concrete foundation. Shear PanelHouse Framing Term Shear Panel refers to particular sections of a wall whether it is interior or exterior that is nailed in a particular pattern to create a shear panel or extra bracing depending on the structure or location. Landing or platform - A landing is the area of a floor near the top or bottom step of a stair.
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Daily Archives: 07 December 7, 2009
Miles for Nothing: How the Government Helped Frequent Fliers Make a Mint
Enthusiasts of frequent-flier mileage have all kinds of crazy strategies for racking up credits, but few have been as quick and easy as turning coins into miles. At least several hundred mile-junkies discovered that a free shipping offer on presidential … Continue reading
Posted in Interesting Comments Off on Miles for Nothing: How the Government Helped Frequent Fliers Make a Mint
About to Lose His Eyesight, Cancer Survivor Jake Olson, 12, Gets Support From His Favorite Team
A kid has cancerous tumors in both eyes, one eye was removed and the other eye was saved through treatment. Cancer reappears eigtht times, and he is able to beat it. Cancer comes back yet again, and he must have … Continue reading
Pastor Offers Sex Offenders A 'Miracle': A New Start
On a recent Sunday morning, a few dozen men and just a few women gather at a little country church near Pahokee, Fla. They sing, pray and stand up to testify about the importance of God in their lives. About … Continue reading
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Winter Olympic Tourch Relay
Boston.com's The Big Picture provides a lot of interesting pictures of the travel of the Olympic Torch. Here are two that caught my eye. This is how it all starts, in Greece with use of a solar reflector. And this … Continue reading
Posted in Interesting, Pop Culture 1 Comment
Smart Baby Case
Designer Pouyan Mokhtarani created the Smart Baby Case – a hard case with autocleaning system to use in disasters or poor condition travels and lifestyles )not more than 2 hours per day because babies always need to be tuch by … Continue reading
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Interesting Shoe Tie
Not only did he tie his shoe during play, but he possession of the ball.
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Have yourself a microscopic Christmas
For most children the challenge is trying to build the biggest snowman. Scientists, however, enjoy taking on altogether trickier tasks. They have built the world's smallest snowman, measuring just 0.01mm across – one fifth of the width of the average … Continue reading
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Sketchy Santas
A blog dedicated to all the sketchy Santas out there. Some are sketchier than others. sketchysantas.com
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Bag of Randomness
First off, thank you all so very much for taking the time to answer my baby products question. WifeGeeding and I are thankful for all your input that I know will make our life easier. Thanks for helping us out … Continue reading
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Kudankulam: Fishermen lay siege to Tuticorin Port
Tuticorin (TN): In a new show of resistance, anti-nuclear protesters onboard around 500 boats on Saturday laid siege to the Port here against loading of uranium in Kudankulam atomic power plant.
Around 3,000 fishermen and anti-nuclear activists from Tuticorin, about 100 km from Kudankulam in neighbouring Tirunelveli District, and elsewhere came in mechanised and country boats and blocked the entry channel for nearly two hours, port officials said.
The officials, however, said there was no disruption of any vessel movement since they had rescheduled ship arrivals and departures in advance taking into account the protest.
"Last night itself we hurried vessel loading and unloading operations. Only the piloting operations (bringing the ship and taking them out) were not done, which resumed after the about two-hour long protest," they said.
Coast Guard, Central Industrial Security Force (CISF) and Marine police personnel kept a vigil as the protesters positioned their boats at the entry channel and raised slogans demanding halting of fuel loading which began on Wednesday.
A group of anti-nuclear activists organised a human chain in Tuticorin town also.
Meanwhile, People`s Movement Against Nuclear Energy (PMANE) leaders, including SP Udayakumar, against whom a court has issued a non-bailable warrant, along with fisher folk staged a `Jal Satyagraha` in the sea at Koothakuzhi, ten km from Kudankulam, forming a human chain.
The protesters stood in knee-deep water holding hands, resorting to such form of stir for the second time in a week. Similar protests were conducted in the sea at Kudankulam, Idinthakarai, Perumanal and adjoining coastal hamlets.
Later, they observed a fast in front of churches in their respective hamlets as part of the multi-layered protests since early this month when the regulatory authorities gave the nod for loading nuclear fuel in the first 1000 MW Russian reactor.
Udayakumar, who is evading arrest in a case relating to the anti-nuclear stir, has also given a call to picket Central Government offices in the state on September 25.
The stir took a violent turn on September 10 leading to the death of a fishermen in police firing in this district.
The first unit was scheduled to be commissioned in December last year but had been delayed by the protests by locals on safety concerns.
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