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|By Marketwired .
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|March 30, 2014 11:30 AM EDT
WASHINGTON, DC -- (Marketwired) -- 03/30/14 -- The Medicines Company (NASDAQ: MDCO) today reported a presentation of a pooled analysis of 5,800 patients in the EUROMAX and HORIZONS-AMI trials, two international clinical trials comparing Angiomax® (bivalirudin) versus heparin with or without glycoprotein IIb/IIIa inhibitors (GP IIb/IIIa) in patients with ST-segment elevation acute myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI). EUROMAX and HORIZONS-AMI studies were presented and published individually in September 2008 and October 2013, in The Lancet and The New England Journal of Medicine respectively.
The pre-specified patient-level data from the EUROMAX and HORIZONS-AMI trials were presented today at the American College of Cardiology's (ACC) 63rd Annual Scientific Session in Washington, D.C.
Lead author, presenter and primary investigator of the EUROMAX trial Professor P. Gabriel Steg, MD, of Hôpital Bichat in Paris said, "The totality of the findings in this analysis confirm the earlier findings of the EUROMAX and HORIZONS-AMI trials, and support the fact that bivalirudin should remain the preferred anticoagulant of choice for clinicians treating STEMI patients undergoing primary PCI."
The totality of the data in the EUROMAX and HORIZONS-AMI trials of 5,800 STEMI patients undergoing primary PCI showed a significant absolute reduction in cardiac death of 0.9% (2.0% for bivalirudin vs. 2.9% for control; OR 0.70, 95% CI 0.50-0.97, p=0.03); absolute reduction in major non-CABG-related bleeding of 3.6% (4.2% for bivalirudin vs. 7.8% for control; OR 0.53, 95% CI 0.43-0.66, p= < 0.0001); absolute reduction in transfusion of 1.7% (2.1% for bivalirudin vs. 3.8% for control; OR 0.57, 95% CI 0.42-0.77, p=0.0002); and absolute reduction in net adverse clinical events (NACE) of 3.1% (8.8% for bivalirudin vs. 11.9% for control; OR 0.74, 95% CI 0.63-0.86, p= < 0.0001). The analysis also showed an increased risk of stent thrombosis, driven by an increase in acute stent thrombosis absolute risk of 1.0% (1.2% for bivalirudin vs. 0.2% for control; OR 6.04, 95% CI 2.55-14.31, p= < 0.0001). The findings were consistent across all examined subgroups.
"As we had seen in the results of the EUROMAX and HORIZONS-AMI trials when they were first presented and published, this analysis underscores that use of bivalirudin, compared with a combination of heparin and a GP IIb/IIIa inhibitor, is associated with significant absolute reductions in risk for cardiac death and major non-CABG bleeding," said Gregg W. Stone, MD, Professor of Medicine at Columbia University College of Physicians and Surgeons, Director of Cardiovascular Research and Education at the Center for Interventional Vascular therapy at New York-Presbyterian Hospital/Columbia University Medical Center and Co-Director of the Medical Research and Education Division at the Cardiovascular Research Foundation. Dr. Stone is the principal investigator of the HORIZONS-AMI trial.
About Angiox/Angiomax
In the United States, bivalirudin is marketed under the trade name Angiomax and is indicated in patients undergoing PCI with provisional use of GPI and in patients with, or at risk of, heparin-induced thrombocytopenia and thrombosis syndrome (HIT/HITTS) undergoing PCI. In addition, Angiomax is also indicated for use as an anticoagulant in patients with UA undergoing percutaneous transluminal coronary angioplasty (PTCA). Angiomax is intended for use with aspirin. Angiomax is not approved for use in patients with acute coronary syndromes (ACS) not undergoing PCI or PTCA.
In Europe, Angiox currently is indicated as an anticoagulant for adult patients undergoing PCI, including patients with STEMI undergoing primary PCI. Angiox is also indicated for the treatment of adult patients with unstable angina/non-ST segment elevation MI planned for urgent or early intervention. Please see full prescribing information available at http://www.angiox.com.
In clinical trials comparing Angiomax and heparin, the most common adverse reaction for Angiomax was bleeding (28%). Other common adverse reactions were headache, thrombocytopenia and fever. An unexplained fall in blood pressure or hematocrit, or any unexplained symptom, should lead to serious consideration of a hemorrhagic event and cessation of Angiomax administration. Angiomax should be used with caution in patients with disease states associated with an increased risk of bleeding.
In gamma brachytherapy, an increased risk of thrombus formation, including fatal outcomes, has been associated with the use of Angiomax. Angiomax is contraindicated in patients with active major bleeding or hypersensitivity to Angiomax or its components.
Please see full prescribing information for Angiomax, available at http://www.angiomax.com.
About EUROMAX
EUROMAX (EUROpean aMbulance Acs angioX trial) was a 2,218 randomized, controlled, open label, international, multicenter study that compared early administration of bivalirudin, which is marketed as Angiox in the European Union, and Angiomax in the US, to heparins with or without glycoprotein inhibitors (GPI). Patients with ST-segment elevation myocardial infarction (STEMI) who were being transported for primary PCI received either bivalirudin or unfractionated or low-molecular-weight heparin with optional GPI (control group). At 30 days, the primary outcome was a composite of death or major bleeding not associated with coronary-artery bypass grafting (CABG), and the principal secondary outcome was a composite of death, reinfarction, or non-CABG major bleeding. Patients who were assigned to the bivalirudin group received a bolus of 0.75 mg per kilogram, followed by an infusion of 1.75 mg per kilogram per hour, which should be continued for at least 4 hours after PCI. The protocol also specified that the dose during the post-PCI interval should be 0.25 mg per kilogram per hour; however, continuation of the higher dose used during PCI was also permitted. Bailout use of a GPI was allowed in the event of giant thrombus or no-reflow.
About HORIZONS-AMI
HORIZONS-AMI, co-funded by a grant from The Medicines Company, was the largest study to focus on the appropriate use of anticoagulation medications and stents in patients experiencing STEMI and undergoing primary percutaneous coronary intervention (PCI), commonly known as angioplasty. This landmark trial was a prospective, single-blind, randomized, multi-center study conducted in 11 countries. Patients undergoing angioplasty were randomly assigned to receive either Angiomax (bivalirudin) with provisional use of GPI or heparin plus GPI. Patients enrolled in the HORIZONS-AMI trial also were assigned randomly to receive either TAXUS® drug-eluting stents or a bare-metal stent.
The two primary endpoints of the trial were major bleeding and net adverse clinical events, a composite of major adverse cardiovascular events (death, reinfarction, stroke or ischemic target vessel revascularization) and major bleeding at 30 days. The major secondary endpoint was major adverse cardiovascular events at 30 days.
About The Medicines Company
The Medicines Company's purpose is to save lives, alleviate suffering and contribute to the economics of healthcare by focusing on 3000 leading acute/intensive care hospitals worldwide. Its vision is to be a leading provider of solutions in three areas: acute cardiovascular care, surgery and perioperative care, and serious infection disease care. The company operates in the Americas, Europe and the Middle East, and Asia Pacific regions with global centers today in Parsippany, NJ, USA and Zurich, Switzerland.
Statements contained in this press release about The Medicines Company that are not purely historical, and all other statements that are not purely historical, may be deemed to be forward-looking statements for purposes of the safe harbor provisions under The Private Securities Litigation Reform Act of 1995. Without limiting the foregoing, the words "believes," "anticipates" and "expects" and similar expressions, are intended to identify forward-looking statements. These forward-looking statements involve known and unknown risks and uncertainties that may cause the Company's actual results, levels of activity, performance or achievements to be materially different from those expressed or implied by these forward-looking statements. Important factors that may cause or contribute to such differences include whether physicians, patients and other key decision makers will accept clinical trial results and such other factors as are set forth in the risk factors detailed from time to time in the Company's periodic reports and registration statements filed with the Securities and Exchange Commission including, without limitation, the risk factors detailed in the Company's Annual Report on Form 10-K filed with the SEC on March 3, 2014, which are incorporated herein by reference. The Company specifically disclaims any obligation to update these forward-looking statements.
Neera Dahiya Ravindran, MD
Vice President, Investor Relations & Strategic Planning
The Medicines Company
+1 (973) 290-6044
Email Contact
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Veteran Bradley Central boys basketball coach Kent Smith, the school's all-time winningest coach with 400-plus victories, has decided to take a leave of absence for at least a year and complete his rehabilitation from knee replacement surgery.
Smith, 52, has coached the Bears for 17 seasons and made five state tournament appearances with runner-up finishes in 2000 and 2003. His grandfather, Tip Smith, also coached the Bears and influenced Kent to enter the teaching and coaching profession.
"I had total replacement of my right knee on July 30," Smith said Tuesday. "At the time I planned to rehab and be back ready to go for the upcoming basketball season. I underestimated the recovery in the sense that I'm pretty pleased with the physical aspect of it, but mentally I'm not 100 percent ready with practice starting up pretty soon."
Smith met with Turner Jackson, the Bradley Central athletic director, a couple of weeks ago and informed Jackson he was considering resigning. Jackson asked Smith to also consider another option – a leave of absence.
"My principal (Todd Shoemaker), who has always supported me, encouraged me to take a leave of absence," said Smith, whose first year at Bradley was the 1996-97 season. "(Monday) I was miserable and I couldn't ask my players to invest 100 percent in our program if I couldn't do that. I'm just not there yet.
"I busted my rear end, but I'm just not ready to coach and it's more mental than physical."
Smith said he's also being putting off for four of five years needed dental procedures and plans to address that in the days and weeks to come.
Assistant coach Chuck Clark will take over the head coaching duties.
Smith began his career rotating between teaching positions at Oak Grove and Black Fox elementary schools after working briefly as his father's American Uniform business.
"After a month I decided I wasn't going to do that," Smith said. "And I don't think he really wanted me working for him either. I went back to school to get my teaching certification."
Smith attended Cleveland High School and spent two years at Tennessee Wesleyan College in Athens, Tenn. He graduated from Middle Tennessee State University in Murfreesboro.
Smith was asked if he plans to return to coaching for the 2014-15 season.
"I can't answer that," he said. "That's the purpose of doing what I'm doing. When I had the procedure, I was told it would take six months to a year to fully recover. I'm hoping that come April or at least in summer camps I would be all in.
"We'll just see. I could barely walk at the district (5-AAA tournament) championship game last season. Really, I was no good to anybody and that led me to this."
In his time directing the program, Smith produced one Mr. Basketball, Josh Hare, in 2000 and had two other Mr. Basketball finalists – Justin Hare in 2003 and Terrence Oglesby in 2005.
Smith has a 436-145 overall record, a .750 winning percentage. His best single-season record was 37-2 in the 1998-99 season. He also had five other 30-win seasons, including a 36-3 mark in 2002-03.
Tip Smith went 325-58 over 10 seasons and won state titles in 19040 and 1942 and was inducted into the Tennessee Sports Hall of Fame in 1975.
Smith had back-to-back losing seasons in 2007-08 (15-16) and 2008-09 (14-16), but posted winning records in each of the past four seasons. The best won-loss mark in that stretched was a 27-7 two years ago.
The veteran coach is 353-119 in regular season play and 73-30 in the postseason. He has won 82.2 percent of his home games (168-39), is 257-107 on the road and sports a 119-33 district record.
Smith has won nine district tournament titles, including six in a row, and finished runner-up four times. In his trophy case are eight region championships -- he won five straight during one stretch -- and five sub-state titles.
(E-mail Larry Fleming at email@example.com)
May 26, 2016
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Until this spring, Grace Baptist Academy senior Jared Roberts wasn't sure if he would have the opportunity to continue his basketball career in college. Then Golden Eagles' coach Jon ... (click for more)
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MURFREESBORO - The old adage of seventh game is the key game in a set proved true for the Hixson boys doubles team of seniors Alex Condra and Richard Vuong. The Wildcats won the key game in both sets for a 6-2, 6-2 win against Cam Presley-Will Richardson (Trinity Christian, Jackson, Tenn.) and advanced to the Spring Fling state D-I A-AA doubles finals Friday at ... (click for more)
Until this spring, Grace Baptist Academy senior Jared Roberts wasn't sure if he would have the opportunity to continue his basketball career in college. Then Golden Eagles' coach Jon Mattheiss reached out to Bryan College men's coach Don Rekoske, beginning a relatively quick recruiting process that culminated Thursday afternoon with Roberts signing scholarship papers with ... (click for more)
The attorney for advisor to Mayor Andy Berke Lacie Stone said she has been thrust into the spotlight, but said she is "the victim of an unprovoked attack" by her husband, Bobby Stone. Attorney John Cavett said it is ridiculous "to suggest that she was the perpetrator." Mr. Stone is facing charges of domestic assault and vandalism. Attorney Cavett said, "It is unfortunate ... (click for more)
The Cleveland City School board unanimously voted Thursday afternoon to offer the job of director of Schools to Dr. Russell Dyer. Dr. Dyer serves as the chief of staff of schools in Collierville, Tn. If Dr. Dyer accepts the school board's contract, he will be paid $132,500 a year. After contract negotiations, the board plans for Dr. Dyer to start at Cleveland City ... (click for more)
It is interesting that Chief Fletcher would deem the handling of the Mayor's encounter as typical or normal. Is the Chief asking the public to believe that all misdemeanor domestic violence arrests include a 4-hour taped interrogation, and delayed reporting after a visit to the Chief's house. Of course, we believe that Chief Fletcher. April Eidson * * * I ... (click for more)
On this, the week of commencement, junior high graduations, and achievement at every level is displayed, we stand with hope and wonder as the next wave of promising Americans gives our nation the reason we pray for our next tomorrow. On Monday, as Vice President Joe Biden addressed 950 cadets who would become 2nd Lieutenants by the end of the day at the United States Military ... (click for more)


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I first learned about the Stress Index in my undergraduate studies. The Holmes Rahe Stress Scale gives a numeric value to many key life stressors, positive or negative. The study was conducted to determine whether the individual was at risk for developing illness based on their level of stress. In ...
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Remarks by William Bennet
By Editorial Staff
Published April 2, 2008
HOUSTON, Texas – Thank you. Let me start by departing from my text. As a trained philosopher and as a sometimes objective commentator for the news media, I'd like to say I think this is a whole lot more interesting than New York.
This is a diverse party in may ways – intellectually. And we can be very proud of that fact. That other party has nothing on us. It's late Summer in Houston at the Astrodome. We're in the process now of getting our team on the field. And we are in this week determining the nature of the game we're about to play.
Ladies and gentlemen, I am proud to stand before you tonight to renominate Dan Quayle as Vice President of the United States. Dan Quayle – I know Dan Quayle. Dan Quayle is a friend of mine and he's a friend of yours and he's a great public servant. I'm particularly pleased to have the honor today because of Dan Quayle's success in sparking a much needed debate about our most important social issues, the values by which we live and the values we convey to our children.
Remember, nothing – nothing more powerfully determines the shape of a child's life than his values, his internal process, his beliefs, his sense of right and wrong. It is the child's values, more than his race, his class, his sex, his ethnicity, his neighborhood, his genes, his background. It is the values that a child is taught that will more determine that child's fate.
And, consistent with our theme tonight, I remind you of what you already know. It is given to families preeminently to provide those values. Now having been buried beneath the Reagan and Bush landslides of the last three presidential elections, the Democratic Party is now eager to wrap itself in the banner of traditional values. But to be a champion of traditional values requires more than rhetoric.
The American people will judge the two parties not only by what they say but by what they do, by what they stand for, and by what they will fight for. So let the Democratic Party invoke the mantra of a new covenant. Our grand old party will continue to hold to our sacred old covenant and the ideals which they embody. America does not need false prophets bearing new covenants. What we need are men and women of character who adhere to old principles.
Family values represent a great dividing line between the parties. This line, be sure to remember, involves very specific matters of policy. For example, we believe that families should be able to send their children to schools that they choose. Not all teachers are parents but all parents are teachers – children's first teachers, children's all but indispensable teachers. And those parents should be able to send their children to schools that affirm the most deeply held convictions of parents.
Second, we believe that our nation's public schools should not be doing things like handing out condoms to our children. Educators should not be allowed to usurp the authority from parents in this and other sensitive areas. Remember, the child is not a ward given to the state for its nurture. The child is a gift of God, given in trust to his parents. And our schools should treat our young people as gifts of God, not as subjects of social experimentation or as young animals in heat.
On our side of the cultural divide line we believe that our government should not subsidize pornography and obscenity. We do not believe that filth is a cultural achievement worthy of public support. Our culture has become increasingly coarse. It has begun to fray our social fabric. Our children have suffered from this. There are, after all, some things that children simply should not see.
It's bad enough that so much of what passes for art and entertainment these days is the rampant promiscuity and the casual cruelty of the movies and television in much of our popular culture. But to ask us to pay for it is to add insult to injury. We will not be intimidated by putative cultural guardians into accepting either the insult or the injury.
We believe, as well, that more of our children should have the opportunity to be raised with fathers in their lives. Young boys and girls who do not grow up with fathers are far more likely to drop out of school, to become promiscuous, to go on welfare, to use drugs, and to commit crime.
In saying this we do not disparage the good, noble and sometimes great effort of single or divorced mothers. I know of what I speak. My mother was divorced and raised my brother and me. Later in my life a stepmother intervened with love and affection and care.
As Barbara Bush said earlier, it is this idea of the family that we embrace; mothers and fathers, stepmothers and stepfathers, adoptive mothers and fathers, foster parents, grandparents, uncles, aunts, brothers and sisters.
So in talking about the family we will not disparage the noble efforts of good women. But in noting the decline of the American family we will say something to the men of America. And to the men of America we say this, man to man. Fatherhood involves a lot more than getting a woman pregnant. Real men, real fatherhood means love and commitment and sacrifice and a willingness to share responsibility and not walking away from one's children.
Let me, as well, very briefly address the tumultuous issue of alternative lifestyles. Heaven knows there are lots of them. This is a free country. Within very broad limits people may live as they wish. And yet, we believe that some ways of living are better than others. Better because they bring more meaning to our lives, to the lives of others, and to our fragile fallible human condition. Marriage and parenthood should be held up because between marriage between husband and wife and in fatherhood and motherhood come blessings that cannot be won in any other way.
We believe these things and we believe them strongly because we believe the family to be our most important institution. We believe our families to be the first, the best and the original department of health, education and welfare. In our time, efforts must be made to preserve and strengthen the family. Heroic efforts, if necessary. And we, this party, will make those efforts.
Let me be clear about one thing. When we talk about traditional family values we are not using code words. We are not seeking a political wedge issue and we are not speaking to demean or to belittle others. Rather, we're seeking to honor and to affirm what is best in us, what Lincoln has called the better angels of our nation.
But there are differences between our two political parties and the differences are real and the differences have consequences. So we Republicans will continue candidly to address the issue of values. We will be civil but we will not yield. We will not be discouraged from discussing right and wrong without embarrassment. We will not be discouraged from defining religion as the anchor of morality, and we will never stop affirming that all real education is the architecture of the soul.
This understanding of what we hold dear, of what we believe, has far too few defenders in our public life. One of the reasons that's the case is that those who candidly speak out on behalf of these matters become the object of assault and caricature by their critics from the adversary culture.
Judging from the Democratic Convention it may now have become politically correct to say you are in favor of the values of family and personal morality. But what is not so politically correct is to be precise about what you mean. What is not politically correct is to stand up against the critics. What is not politically correct is to say that there are some things that we stand for and there are some things that we will not stand for.
Ladies and gentlemen, it may not come as a great shock to you, but let me say it anyway. I am very proud to tell you that Dan Quayle is not politically correct.
Dan Quayle has stood for family values. Dan Quayle has stood up against his critics. He has been principled. He has been courageous. And in response, he has been belittled. But he has not been silenced. In Dan Quayle we have had a case study in courage under fire. Through it all this good and decent man has demonstrated his grace, his resolve, his resilience. He has earned our respect and we will stand by our man.
Ladies and gentlemen, I am pleased and honored to place in nomination for the Vice Presidency of the United States our friend Dan Quayle.
Forerunner - Home » The Forerunner Newspaper » Pro-family
Your comments are welcome!
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text:
LOVER OF THE OCEANTIDE, submitted by Byrd. This is why all snotfaced kids under the age of 40 shouldn't be allowed to use computers or talk or go out into public or do whatever the hell they do to be so goddamn annoying.
i have always wanted to be a true friend to whoever needed on i have mostly wanted to be surrounded with bodybuilder friends becase a true beautiful muscle man who is on fire for jesus really cry because its just simply a a desire of my heart to pray and interveen and be in agreement for bodybuidlers everyday as well my best friends are kevin / christine / baron / matt / matthew / rob / robert / joey........
God delivered me from homosexuality on august 12,2000 and i am so happy to be free from it forever amen. i have no desire for a man in that reguars for to love as a freind and to hold and hug yes but nothing anal like that b/c i wanna strive to be like jesus all the time and yes there are those who hate me b/c i have changed or those who hold the past against me saying i wont change i cant or its impossible but if jesus can die on a cross to make away out for me then yes i can be free i dont care what anybody says nothing or nobody is worth loosing the relationhip i have with my father in heaven. but i wanted to open up with this so you will have a better view of me but if u have never asked jesus in your heart and you wanna change God with you as you read this write now! and you can be free but remember you will be free in God's timing! to be saved and escape the tribulation as it says in luke 21:36 we must pray that we are accounted worthy to miss the terrible things that is about to happen and that we are able to stand in front of the Son of Man.
i collect telephones / caller ids / shirts (anything that is silk / spandex / polyester / or muscle t-shirts of all colors at walmart for cheap prices / cds / pens / anything that is not normal or common like anybody else does :) i love driving back and forth to see my best friend christine in morgan city,la and 2!!!!!!!!
What the hell is wrong with this braindead gutterball? Nothing that a little drainage pipe across the skull treatment can't fix.
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Wtf are these weird things you people keep posting. are they a kind of pastry
Awful Links of the Day spotlights the worst and weirdest websites on the internet. And we're not talking "weird" in a good way either.
Copyright ©2016 Rich "Lowtax" Kyanka & Something Awful LLC.


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- 2,306 Posts. Joined 8/2013
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Topics Discussed
- productAudio Technica L3000tagged by System, 5/11/11
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Headphone Sightings 2 - Page 656post #9826 of 1231110/14/13 at 12:27pm
Gear mentioned in this thread:
post #9827 of 1231110/14/13 at 12:28pm
- "sound signature is mega fun, and quite surprising for a small supra-aural set of phones""value, sound, modification possibilities, aesthetics"
- "Gorgeous hand crafted design, transparent mids, intimate vocals, sparkly clear highs, deep detailed bass, very open sounding, easy to drive""Great sound, Detailed, Resolution, Warm, "
- wolfetan44
- Trader Feedback: +12
- offline
Quote:post #9828 of 1231110/14/13 at 1:19pm
- 4,449 Posts. Joined 3/2012
- Location: San Francisco
- Select All Posts By This User
- TheJesusGuy
- Trader Feedback: 0
- offline
- 321 Posts. Joined 10/2012
- Location: East Sussex, England
- Select All Posts By This User
Well there's a guy in my college class with V-Moda LP2s. I bring in my M50s every day and when he used them he asked me where the bass is. I said the LP2s have too much and it muds up the mids in anything other than electronic. Not to mention the pads are way too small.post #9829 of 1231110/14/13 at 2:07pm
- ibob4tacoz
- Trader Feedback: 0
- offline
Quote:Welcome to reality.post #9830 of 1231110/14/13 at 2:19pm
- 1,390 Posts. Joined 6/2013
- Location: Arizona, USA
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- lookingforIEMs
- Trader Feedback: 0
- online
post #9831 of 1231110/14/13 at 2:21pm
- 1,184 Posts. Joined 8/2012
- Location: Singapore
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- ibob4tacoz
- Trader Feedback: 0
- offline
post #9832 of 1231110/14/13 at 2:37pm
- 1,390 Posts. Joined 6/2013
- Location: Arizona, USA
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Ok Boys since no-one else is taking charge, I will, our first course of action is to pick a pair of Headphones that we can fully agree kick the arse of those gosh darn "B***s", BTW no M50's since those are basically sibilance-ridden cans that are okay (great imaging capabilities, meh everything else) at their price point.post #9833 of 1231110/14/13 at 2:40pm
my suggestion would be audio technica ws99 as they are very good at mainstream genres, are comfy, and don't cost as much as beats (they go for around 180 on amazon)post #9834 of 1231110/14/13 at 2:51pm
- Magdumper
- Trader Feedback: 0
- offline
At my college I always see beats of all types, one or two m50s, a lot on cheaper sony on ears, some bose ie2, and a bunch of in ears and earbuds(a surprising number of them arent stock phone buds, but 20$ philips etc). Theres this one music producer I talked to because he had dt770 pro 80 ohms and i see him often. Other notable headphones are bose qc15s and ae2s I see somtimes, and Ice seen one b&w p5... not that bad I guess.post #9835 of 1231110/14/13 at 3:06pm
- 141 Posts. Joined 1/2013
- Location: Del Mar, CA
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- Ishcabible
- Trader Feedback: +49
- offline
- 6,303 Posts. Joined 1/2009
- Location: Northern Illinois/Boston
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Just saw someone with a Harman Kardon CL.
And I've always found it great how so many young people have been joining lately. I discovered this place about six years ago when I was 13 and when I joined, I was one of the few(ish) young members, but now I think there are enough young people to actually make up a significant fraction of the active user base.post #9836 of 1231110/14/13 at 4:27pm
- wolfetan44
- Trader Feedback: +12
- offline
- 4,449 Posts. Joined 3/2012
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Nooo! You reminded me of something, but its too late! I was supposed to call AT about the WS99 today..post #9837 of 1231110/14/13 at 4:49pm
- kimvictor
- Trader Feedback: +13
- offline
- 4,174 Posts. Joined 6/2012
- Location: MA, USA
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Saw a friend with M50. That's the second one at school! He hated beats, and he knew how good M50s were.post #9838 of 1231110/14/13 at 8:17pm
- Allucid
- Trader Feedback: +2
- Caution: Incomplete trades.
- offline
Quote:LP2s muddy vocals compared to the M100.Originally Posted by TheJesusGuy
- 834 Posts. Joined 11/2012
- Location: Perth, Australia
- Select All Posts By This User
Well there's a guy in my college class with V-Moda LP2s. I bring in my M50s every day and when he used them he asked me where the bass is. I said the LP2s have too much and it muds up the mids in anything other than electronic. Not to mention the pads are way too small.
Could EQ it. Imho M100 is better in every way than the LP2.post #9839 of 1231110/14/13 at 10:03pm
- BillsonChang007
- Trader Feedback: +3
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- 5,849 Posts. Joined 7/2012
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There are so many reasons I won't buy the GTA 5;
1) I don't have any gaming console that is compatible with GTA 5. My PC is suitable but running out of space... XD
2) if I buy GTA 5, what about headphones? Amp? DAC? DAP? (First audiophile world problem )
3) there's no good headphone in the game
4) I don't play a lot of games and I tend to spend more time with my gears
Yayyyyy! Good to see so many Head-Fiers here around my age
My suggestion for B***s alternative are as follow;
Sennheiser HD439
Ultimate Ears UE4000/6000
Sennheiser Momentum >post #9840 of 1231110/14/13 at 10:18pm
- linglingjr
- Trader Feedback: +7
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GTA 5 needs to hurry up and come out on PC.... Also, another young-ling (get it? Ling?) here I'm 17.
TheJesusGuy your profile picture is amazing. Doge meme lifestyle is by far my favorite.Return HomeBack to Forum: Headphones (full-size)
- Headphone Sightings 2
Gear mentioned in this thread:
- "sound signature is mega fun, and quite surprising for a small supra-aural set of phones""value, sound, modification possibilities, aesthetics"
- "Gorgeous hand crafted design, transparent mids, intimate vocals, sparkly clear highs, deep detailed bass, very open sounding, easy to drive""Great sound, Detailed, Resolution, Warm, "
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2015 SL4 Roubaix Specialized Bike in mint condition. Medium size endurance bike. Shimano Sora groupset. Espoir Elite 700x25c tires. 56cm with 700c wheel size. Accessories included such as helmet pedals riding gloves1 month ago on oodle.com
All carbon frame and fork with Shamono 105 components, Triple crank with ten speed cog makes this bike perfect for climbing hills. Carbon frame creates a comfortable ride especially on longer rides. Very like-new co1 month ago on SpreadMyAd
$1500 OBO. Bike is in great condition. Just replaced the chain and cassette. Upgraded the wheels to Roval Fusee SL from the EL. Comes with a couple different stems. Size 3XL. Look at photos for other specs.Call/Text Allen @801-808-19691 month ago on Local Classifieds
Top quality, perfect condition Specialized Roubaix Elite Apex Compact road bike for sale by a meticulous owner. It comes with all the bells and whistles. You can do some research on this bike. It's the real deal. It1 month ago on SpreadMyAd
Great road bike. Purchased for 1500 originally. New tires and freshly tuned. Ready for you to enjoy. Carbon forks and seat post. Shimano 105 all the way around. Never crashed.1 month ago on Local Bike Trader
Owner is a bike mechanic for a shop. Bought new in early 07' Full carbon frame, fork, seatpost, FSA carbon crankset, Time RSX carbon Ti pedals. Mavic Kysrium ES wheel set w/ bags and tool. includ. extra set of new s1 month ago on US Classifieds
Specialized 2013 Roubaix Sport Base Road Race Bike - 54 - Carbon Color - Like new - Purchased in 2013 - less than 500 mis - Purchased from Erik's Bikes - 1799-New - 9991 month ago on oodle.com
2009 Fuji Roubaix Road Bike (56cm stem) with limited mileage. Shimano 105, Ultegra and Dura Ace components. Carbon forks. This is an excellent performance bicycle for someone who is looking to get started with cycling1 month ago on oodle.com


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Houses to let in Elizabeth Close, West End, Southampton SO30 - 3 bedrooms
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Chalk Hill, West End, Southampton SO18Semi-detached house to rent - 3 bedrooms
**guide price £950 to £975**Available now is this lovely 3 bedroom semi detached house that has undergone some internal renovation having been re decorated throughout with newly installed carpets .The property has gas central heating, full UPVC double ...
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- Bitterne (1.6 miles)
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National Youth Theatre Announces 60th Season - West End Premie...Paul Roseby , Artistic Director and Chief Executive of the National Youth Theatre of Great Britain (NYT) has today announced a new season of work for the company in celebration of their 60th anniversary year. Founded in 1956 the NYT is the ... Broadway World, 1 month ago
Making Southeast Asian Cultures: From Region to World, Apr 22
The aim of this conference, jointly sponsored by the Center for Southeast Asia Studies at UC Berkeley (Director: Prof. Pheng Cheah) and the Center for Southeast Asian Studies at UCLA (Director: Prof. George Dutton), is to reopen the question of ...EnvironmentGuru.com, 1 month ago
A cold fire
Illustration by Abro For most novelists whose first novel is a raging success, the second one is a tough act to follow. Stephen Kelman's first novel Pigeon English was highly acclaimed and nominated for the Man Booker Prize, and his second novel, ...DAWN Group, 2 months ago
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Google Earth Day 2016 Doodle Google has released a doodle celebrating Earth Day 2016. April 22nd is celebrated as World Earth Day and the tech giant has yet again showed why it is one of the most innovative companies in the world. Google Earth Day 2016 Doodle is amazing and it is consisting of 5 …Read more
Maggi Hot & Sweet Ketchup Maggi Hot & Sweet Ketchup has released a TVC featuring Nawazuddin Siddiqui and Javed Jaffery as a wife. This is one of the hilarious video you will see. The combination is quite different just like the tag line of the brand- Its different. Nawazuddin Siddiqui is a husband …Read more
Make your own VR goggle using Coca Cola cardboards Virtual Reality (VR) is the future and many companies are trying hard to make their footprints in the VR industry. Facebook has Oculus, Samsung has VR gear, Google has cardboard etc. But there is another player who has joined the race with free VR goggles and that …Read more
Aaj Tak released "Ankhen Khol De" campaign Aaj Tak claimed to be India's fastest news channel has released launched a campaign of "Ankhen Khol De" to re-assure its positioning as the "sabse tej news channel" (Fastest news channel). The commercials are designed in a hilarious black and white which takes a dig at current …Read more
Airbnb says Don't go There, LIVE There! Airbnb, the world's largest accommodation provider which owns not a single room has come up with this brilliant campaign of "Don't go There, Live There". Airbnb Live There Airbnb launched the campaign "Live There" to focus on localised places rather than a tourist destination. The …Read more
Mauka Mauka – India vs Pakistan ICC WT20 2016 is back Cricket world T20 has already started and people are waiting for the famous Mauka Mauka ad series which jolted the marketing world in the last year's cricket world cup So those people who are waiting for the same, its good news, Star Sports have …Read more
Moto X- Interactive Print Ad in Wired Motorola launched its new Moto X smartphone with a lot of new features and technology updates. One thing which is attracting the customers is its ability to customize the phone's color, engraving, back side etc. So, Motorola is set to become the dell of smartphone. To make sure …Read more
AsiaNet News is making eye balls roll ! AsiaNet News the No 1 news channel in Kerala for more than two decades as proclaimed by them in their latest print ads, they are sure making many eye balls rolls with these amazing ads. They are targeting not the customers but the sponsors this time by …Read more
Amazon Neutralizing Flipkart's BigAppShoppingDays with #AppTreasureHunt Amazon is certainly proving to be the best marketer when it comes to e-commerce category. When the shoppers are giving attention to the BigAppShoppingDays of the Flipkart there is this world's dominate e-commerce player with its #AppTreasureHunt is gaining the attention of the shoppers and killing the flipkart's BigAppShoppingDays. What …Read more
Dove and Twitter join hand to make things positive #SpeakBeautiful In the midst of all negativities in the country from bad loans defaulters to job cuts to appraisal month Dove and Twitter has join hands to develop what it can be a best marketing stunt of the year. Dove and Twitter has developed a tool …Read more
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Kodi 16 has been marked FINAL in git and I've compiled and published the RPM for it. +Mageia.Org
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Stig-Ørjan SmelrorGeneral Discussion -
Unofficial builds of Kodi for your pleasure...
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Kodi 16 has been marked FINAL in git and I've compiled and published the RPM for it. @112506136335565826417
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- Life UniversityLife, 1972 - present
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I'm into a lot of new-age stuff and I'm on a path to enlightenment. Have my ups and downs, like everybody else. Wishing I was special, like everybody else.
Fan of Bashar, Eckhart Tolle, Steve Pavlina, Krishamurti, pornstars and life, the universe and everything.
Anxiety and depression. I have a lot of ideas that I love talking about and while doing it I learn so much.
I love Trance. Infected Mushroom is the favorite at the moment. Listening to Progressive House music from di.fm on my tablet.
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Brian Casel
Founder, Restaurant Engine
Are you taking advantage of the benefits that mobile marketing can offer your restaurant? If so, how is it working for you? Is it helping you bring in more customers, or are you still waiting to see the results?
Many restaurant owners have realized the value that a mobile website offers for their business. However, there are still those who haven't yet jumped on the mobile marketing bandwagon — or they aren't making proper use of this type of marketing. Are you one of them?
Whether you are using mobile marketing, or you haven't started yet, here is a look at 5 mobile mistakes that you need to avoid on your restaurant's website:
1. Not Having a Mobile Site
The biggest mistake restaurant owners can make when it comes to mobile marketing is not having any mobile website at all.
Consider the following statistics regarding mobile use, and if you aren't making use of a mobile website, there is no doubt that you will be wondering why:
What do these statistics mean to your restaurant? It means that mobile devices are quickly becoming the primary way that customers will find you. If don't have a mobile website, you stand to lose a lot of potential business.
2. Separate Mobile and Desktop Sites
Having two separate website designs — one for desktop and one for mobile activity — can impact your success. Instead, you should take advantage of responsive web design.
What is responsive web design? It is an approach to website design that responds to the device that a user is using to view a website. A site that features a responsive design will adjust to the screen size, orientation and the platform that a user is viewing the site on. In other words, the site will seamlessly adjust to use on different mobile devices and on desktops.
3. Using Flash
Under no circumstances should you have a Flash website.
A Flash site has definite disadvantages that can greatly impact the success of your restaurant, especially in regard to your mobile website usability. Why? Well, Flash websites can't be accessed on mobile devices because they don't support Flash. This means that mobile users won't be able to view your website from their mobile device. At all.
Also, Flash websites are difficult or even impossible for search engines like Google to crawl and index. If the search engines can't see or understand the content on your site they won't be able to rank you for your relevant keywords.
If you have a Flash website you're likely missing out on traffic from mobile users and search engine users.
4. Non-Visible Contact Information and Addresses
If your contact information or your address isn't easily visible from your mobile site, how do you expect anyone to be able to find your restaurant? If you want your potential customers to find your restaurant, you have to make sure your contact information and address is visible.
The best recommendation is to include your information, including your address, on every page in the footer of your website. This is a common place for contact information so your website visitors will quickly be able to see how to find you and search engines will find the info as well and they'll list it properly in search results.
5. Having a PDF Menu
If you have a PDF menu, this could pose definite problems. Your customers will have to navigate away from your site, and they'll have to open up a separate PDF document, which means that they either have to zoom in or strain their eyes to read it. This isn't exactly the best user experience.
And again, PDF menus can be difficult for search engines to index. The engines have gotten better and do rank some PDFs now, but web-based menus are still a better option. They're easier for people to use and when you share menu items on social media from web-based menus the social sites will pull in rich information like the image, description and more.
If any of these points apply to your restaurant, you are probably in need of guidance for proper mobile website design and function. We can help you design a mobile site that will allow you to reach more customers, improve their experience with your site and increase your business.
These are some of the common mistakes we see with restaurant websites. Did we miss any? We want to hear your tips in the comments!
Brian Casel is the founder of Restaurant Engine, a website design solution for restaurants. Get a free Restaurant Website Checklist on the Restaurant Engine Blog. Email Casel at email@example.com.
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- Anonym
- Australien, Man, 41+
- Nybörjarnomad
- 3 Recensioner
This is just a lovely place, run by lovely people. If you like courtyard architecture, then this is your kinda place. You are welcomed into the serene family home, essentially, but the place is spacious enough so that you have plenty of privacy. Jacky (Mr Dan) is a man with long experience in the tourist biz in Pingyao, and he knows what people want. I can say no more than that some day soon, I hope, you will see my photos, which I did for free, of the Harmony Hotel on its new website,
- lenamvv
- Australien, Mixad grupp, 25-30
- Globetrotter
- 52 Recensioner
The room itself was fantastic and we absolutely loved the traditional bed. But both the address and the directions to the place were very very wrong and my partner and I spent over an hour and a half trying to find a place that simply wasn't there... (And only did so with the help of a random hotel who informed us that the place we were looking for had moved). We travel a lot and this is the first time something like this has ever happened to us. Needless to say we weren't impressed.
- Anonym
- Nederländerna, Par, 18-24
- Globetrotter
- 22 Recensioner
We stayed in a very nice double room! The room is and the rest of the guesthouse is in old Chinese style and comes with a lovely garden. They do have 2 locations in town, the one we stayed is more like a hotel and the other one has dorms and has a bar. Therefore we don't know anything about the dorms!
- Anonym
- Nederländerna, Man, 25-30
- Nybörjarnomad
- 2 Recensioner
Beautifully restored courtyard hotel with a very friendly staff. The Chinese and English breakfast options are both good.
- Anonym
- Tyskland, Mixad grupp, 25-30
- Nybörjarnomad
- 1 Recension
Very nice Staff, great Location and really beautiful! Best Hostel were we have been in China .
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