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|By Business Wire
Article Rating:
|November 12, 2012 09:50 AM EST
The OASIS international consortium has launched the Cloud Application Management for Platforms (CAMP) Technical Committee, a project to define the interoperability standard for managing applications in Platform as a Service (PaaS) environments. CAMP will leverage similarities between commercial and open-source PaaS products to produce a simple API that is language-, framework-, and platform-agnostic. Using CAMP, companies will be able to migrate their cloud applications from one PaaS vendor to another by mapping the requirements of applications to the specific capabilities of the underlying platform.
"Companies are starting to experiment with PaaS, but even as they do, it becomes clear that variations between the vendors' application interfaces will make it hard to move applications from platform to platform. That looks a lot like vendor lock-in, and it's putting customers off," said Rachel Chalmers, VP of Research at The 451 Group. "It is encouraging to see that this issue has been grasped by the vendor community and is being addressed within the OASIS framework."
"CAMP's goal is to define a simple standard RESTful API along with a JSON-based protocol, with an extensibility framework that enables interoperability across multiple vendors' offerings. Using CAMP, users can manage their application lifecycles and move applications between clouds easily," said Martin Chapman of Oracle, chair of the OASIS CAMP Technical Committee. "We expect CAMP to foster an ecosystem of common tools, plugins, libraries and frameworks, which will allow vendors to offer greater value-add."
Work on CAMP was initiated in late 2010 by a group of seven companies, Oracle, Red Hat, Rackspace, Cloudsoft, Huawei, CloudBees, and Software AG. They transitioned the project to OASIS in order to ensure CAMP would benefit from broad industry participation in an open, collaborative setting.
"CAMP is one of several new Cloud standardization projects at OASIS that make use of JSON and REST," noted Laurent Liscia, OASIS executive director and CEO. "We see the standardization of CAMP as an important step in guiding the industry into an ecosystem of interoperable and portable cloud systems."
The CAMP Technical Committee is open to all interested parties, and new members are encouraged to join at any time. Archives of the work are accessible to both members and non-members, and OASIS invites public review and comment on the work.
Support for CAMP
"Enterprises are getting serious about hybrid cloud computing – combining their on-premise capability with cloud service provider offerings. Enterprises are also zeroing in on PaaS – cloud middleware if you will – as the most effective way of exploiting cloud. However, to de-risk their hybrid cloud strategy and avoid PaaS lock-in, they view genuine multi-cloud support as absolutely essential and the work of the OASIS CAMP TC as critical, since cloud-agnostic application management is the key to cloud interoperability."
-- Duncan Johnston-Watt, CEO
"Organizations clearly desire better cloud portability, usability and interoperability for PaaS environments. JumpSoft is committed to supporting open standards in our application management products. CAMP provides a standard API for cloud application management solutions to ensure customers will have a choice in their cloud technology and services."
-- David Sawyer, CEO
"As part of the OASIS Technical Committee for CAMP, Oracle looks forward to continuing to help define a simple REST-based approach for management of cloud-based applications. In addition, CAMP can provide a framework for extensibility to support the evolution of products, while enabling portability across clouds and compatibility with PaaS-aware and PaaS-unaware application development environments."
-- Jeff Mischkinsky, senior director, Oracle Fusion Middleware
"As a Sponsor member of OASIS, Software AG welcomes the formation of the CAMP Technical Committee. As a co-author of the CAMP specification, we hope our contributions to this TC effort will serve to advance CAMP as a standard that is broadly adopted, enabling interoperability between vendor products while offering increased choice for customers. We are excited about the emerging standards efforts in the Cloud space, that is expected to transform the way business is done in the future."
-- Prasad Yendluri, VP & Deputy CTO
"Standing Cloud is committed to helping cloud customers avoid lock-in, so that they can leverage the cloud without limiting their future options. Industry standards are the most powerful way to ensure this flexibility for the long term, and we are enthusiastic about our participation in the OASIS CAMP Technical Committee to help realize that vision."
-- David J. Jilk, CEO
Additional information:
OASIS CAMP Technical Committee
About OASIS:
OASIS (Organization for the Advancement of Structured Information Standards) is a not-for-profit, international consortium that drives the development, convergence and adoption of open standards for the global information society. OASIS promotes industry consensus and produces worldwide standards for cloud computing, content technologies, business transactions, security, privacy, SOA, the Smart Grid, emergency management, and other applications. OASIS open standards offer the potential to lower cost, stimulate innovation, grow global markets, and protect the right of free choice of technology. OASIS members broadly represent the marketplace of public and private sector technology leaders, users, and influencers. The consortium has more than 5,000 participants representing over 600 organizations and individual members in 100 countries.
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text:
Is aviane the same thing as lutera?
- Posted:
- 29 Dec 2009 by Princess Haydee
- Topics:
- aviane, lutera
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text:
Begin your adventures in the Galapagos on Baltra Island. Fly into Baltra, an arid, uplifted island dotted with salt bushes, prickly pear cactus, and palo santo trees. Head to the harbor and board your cruise ship.
Journey across to Santa Cruz Island for a visit to Dragon Hill in the afternoon. Located on the northwest side of Santa Cruz, this site features a trail leading to a hyper-saline lagoon, home to a variety of bird species. Take a short walk up the hill and soak in the stunning view of the islands and bay below.
Today begins with a visit to Black Turtle Cove, a small, exclusive destination nestled into the northern side of Santa Cruz. Surrounded by red mangroves, this quiet cove constitutes an ideal nursery for a variety of sharks and rays. No landing sites exist in the cove, so you can either paddle in with a kayak or a panga. Observe large groups of white and black-tip reef sharks, hammerhead sharks, and schools of golden and spotted eagle rays. It is also possible to spot sea turtles, pelicans, and herons in this unique environment.
In the afternoon, journey on to Chinese Hat, a small islet off of Santiago. Named for its distinctive shape, Chinese Hat is a recent volcanic cone that exhibits fascinating lava formations. Admire its lava tubes and flows, and observe its entertaining colonies of sea lions and penguins.
Cruise to Genovesa Island today, beginning at Darwin Bay. Darwin came into existence when Genovesa's crater collapsed into the sea, leaving beautiful white coral sand beaches in its stead. This island is favored by bird-watchers, boasting numerous species including red footed and masked boobies, wandering tattlers, lava gulls, whimbrels, and various herons. A trail takes you across the island and up to a cliff edge. From here, admire the incredible view of the island landscape below.
In the afternoon, ascend the southern plateau of Darwin Bay, known as El Barranco. This area is a popular nesting site for masked and red-footed boobies as well as storm petrels and short-eared owls.
Venture to Bartolomé this morning, an island boasting some of the most beautiful scenery in the archipelago. Bartolomé's landscape consists of a spectrum of features including volcanic cones, lunar-like craters, lava fields, and Toba. Its two breathtaking beaches are home to sea turtles and a rare colony of Galapagos penguins.
This afternoon, visit Santiago Island, located in the west-central part of the Galapagos. It is still volcanically active, spotted with young lava flows and cones visible from many vantage points, including outerspace!
Today get to know Santa Cruz Island, beginning with a tour of the picturesque highlands. Take a trail from Bellavista, through an agricultural area, along the National Park boundary, the Miconia zone, and into the fern and sedge zone. On a clear day, enjoy views of rolling hillsides and extinct volcanic cones.
Journey back to Baltra for your departing flight.
|Galapagos Suite
|Matrimonial Suite
|Sea Star Suite


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Amos Sparks, Sr., 83, died on January 13, 2013 at a local health care facility.
Amos was formerly employed at Mueller Company. He was of Baptist faith. His hobbies include riding motorcycles and traveling.
He was preceded in death by his wife, Idella Sparks; mother, Carrie James.
He is survived by his five children, Amos Sparks, Jr., Chattanooga; Carolyn (Edgar) Dillard, Chattanooga; Carol Lumpkin, Ringgold; Marcus (Bonnie) Sparks, Colonial Beach, VA; Gloria (Willie) Bone, Woodstock, GA; grandchildren, great-grandchildren; sisters, Doris Terrell, Los Angeles; Ruby (Arthur) Murphy, Phoenix; Gladys (General) Winston, West Point, GA, and Jenell (Johnny) Owens, Lanett, AL; a host of nieces and nephews and ex-wife, Margaret Sparks.
Graveside services will be held at 10 a.m. on Friday, Jan. 18, at Forest Hills Cemetery with Pastor Edward Ellis officiating.
The body will lie in state after noon on Thursday, Jan. 17, at John P. Franklin Funeral Home, 1101 Dodds Ave., 622-9995.
May 24, 2016
Terry Griffith, 58, of Rossville, Georgia, died on Monday, May 23, 2016. He had worked for American Manufacturing for 16 years and was a former employee of Fletcher-Bright Realty. He ... (click for more)
Thomas David Gaddy, 56, of Chattanooga, died on Friday, May 13, 2016. Arrangements will be announced by Covenant Funeral & Crematory, Crox family owned and operated, ... (click for more)
Lillie McKamey, 86, of Rossville, Georgia, formerly of Chattanooga, died on Sunday, May 22, 2016. She was born January 14, 1930 in Chattanooga to the late George and Janie Smith. She was ... (click for more)
Terry Griffith, 58, of Rossville, Georgia, died on Monday, May 23, 2016. He had worked for American Manufacturing for 16 years and was a former employee of Fletcher-Bright Realty. He was a member of Glory Road Baptist Church. Terry was preceded in death by his father, Elvin Griffith and step-son, Brandon Smith. Survivors include his wife of 15 years, Trena ... (click for more)
Thomas David Gaddy, 56, of Chattanooga, died on Friday, May 13, 2016. Arrangements will be announced by Covenant Funeral & Crematory, Crox family owned and operated, www.CovenantFuneral.com . (click for more)
Mary Sue Pickens Liner, 71, of Calhoun, Tennessee, passed away Sunday, May 22, 2016 in a Chattanooga Hospital. She was born in McMinn County and grew up in the Claxton Community. She was a member of the Hiwassee Baptist Church. She was preceded in death by her parents, Clyde and Katherine Wilson Pickens; and sisters, Pauline Yarber, Emma Peters, Nellie Dennis, Rachel ... (click for more)
Michael S. Hendricks, 64, of Georgetown, Tennessee, passed away Saturday, May 21, 2016 at Memorial Hospital in Chattanooga. He was the son of the late Walter and Barbara Hendricks; and was also preceded in death by his common law wife, Jessie Huffaker; and step-sons, Ricky "Rocko" Huffaker, Garry Huffaker and Hal H. Huffaker Jr. He is survived by his sister, Susan Bishop ... (click for more)
Police Chief Fred Fletcher said Tuesday that the community will have input on the placement of cameras designed to deter crime. He told the City Council at a budget hearing that the cameras are part of a Real Time Intelligence Center designed to quickly analyze crime patterns so officers and detectives can react faster and with more knowledge about the situation. Chief Fletcher ... (click for more)
A robbery arrest was made after the victim got a new phone and then had pictures from her stolen phone uploaded to the new phone to her Cloud account. Among the pictures uploaded were photos of the robbers. The female victim identified Seth Benjamin Hardnett, 18, of 1703 E. 14th St., as one of the robbers from the incident on April 12. Hardnett was charged with aggravated ... (click for more)


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text:
Laura Branigan Artist Bio and Lyrics
The '80s artist Laura Branigan was born on the 3rd of July 1957 in Brewster, New York. She is perhaps best known for her 1982 hit "Gloria," for which she won a Grammy Award nomination. The following year, she released the Number One hit, "How Am I Supposed to Live Without You." Other well known Laura Branigan hits included "Solitaire," "The Lucky One," "The Power of Love," and "Spanish Eddie." Laura Branigan was of Italian and Irish descent. In addition to her music career, she was also an actress.
At the time of the release of Laura Branigan's second album, Branigan 2, European style synth pop was on the rise, helping her earlier single, "Solitaire," make it to the charts. While she had had an earlier hit in the form of "Gloria," 1983's Branigan 2 would cement her fame and ensure she was not merely a one hit wonder. That album contained "How Am I Supposed To Live Without You," which contained lyrics written by the then unknown singer Michael Bolton. The track would spend three weeks in the top position on the Adult Contemporary charts in the United States.
Laura Branigan died in August of 2004 of a brain aneurysm, which had also caused the deaths of both her father and her paternal grandfather. Laura Branigan was cremated, and her ashes were distributed over the Long Island Sound.
The albums of Laura Branigan include Branigan, Branigan 2, Self Control, Hold Me, Touch, Laura Branigan, Over My Heart, The Best of Branigan, and The Essentials: Laura Branigan.
Random 80's Artist
Vangelis -It was the year 1981 in which Vangelis first rose to international prominence, with his score to the movie Chariots of Fire, which was set in 1924 at the Paris Olympics. Although it has been argued that an electronic music score was not well suited for a period piece, the score to the film did exceptionally well. Chariots of Fire would go on to win...
80's Band Bio Laura Branigan biography and videos.


text:
M.L. Barber
M.L. Barber wrote descriptions of Florida for tourists from other states.
Available Works
Individual Passages
- Ocala to Tampa by Train
- The author describes the route from Ocala to Tampa Bay, focusing on the beauties he sees upon arriving in Tampa.
FCIT. (2016, May 24). M.L. Barber author page. Retrieved May 24, 2016, from http://etc.usf.edu/lit2go/authors/27/ml-barber/
FCIT. "M.L. Barber author page." Lit2Go ETC. Web. 24 May 2016. <http://etc.usf.edu/lit2go/authors/27/ml-barber/>.
FCIT, "M.L. Barber author page." Accessed May 24, 2016. http://etc.usf.edu/lit2go/authors/27/ml-barber/.


text:
LOS ANGELES - An American collector has become an overnight multimillionaire after a set of 65 glass negatives he picked up at a garage sale turned out to be genuine Ansel Adams works, he and his lawyer said Tuesday.
JOHANNESBURG – A 17-month-old tiger escaped from the back of a pick-up truck while it was being driven to a veterinary clinic in South Africa, triggering a helicopter search by police and wildlife experts.
NEW DELHI – An Indian court has slapped a hefty fine on a woman who cited her husband's sexual impotence as grounds for divorce, a report said Tuesday.
DENVER – A black bear attracted by the smell of a peanut butter sandwich managed to open the door of a car, climb in and got stuck, knocking the gear stick into neutral and sending the car rolling down a slope into trees.
GENEVA - Three Polish tourists had to be rescued by helicopter from a Swiss mountain after embarking on a climbing trip wearing only summer shoes and light clothing, police said Monday.
LONDON – A closed order of French nuns have signed an album deal with Universal Music, the record label announced Sunday, after a worldwide search to find the best female singers of Gregorian Chant.
POZNAN, Poland – For Poland's army of vodka tasters, the rules are strict: no smoking, no coffee, and no perfume, not to mention to the 6 a.m. starts.
LONDON – The strongest and most expensive beer ever created sold out within hours Friday, a Scottish brewery said, as they courted controversy by packaging the bottles inside the bodies of stuffed animals.
NEW YORK – The Force was with a man when he robbed a bank wearing a Darth Vader mask and a cape.
NEW YORK - She loves the taste of blood, hates the sun, and, if you ask, will tell you she died in a train accident back in 1892: meet Seregon O'Dalley, a would-be vampire living in New York.


text:
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Dominatrix Audry Hollander tells her submissive partner to undress and then she wraps him in plastic wrap. After toying with him she starts to cut open the plastic and releases him bit by bit. She fingers her ass while he masturbates and then they add on even more kinky fetish action.22 min.


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Welcome to Scotland's Hotels of Distinction
We offer a collection of quality, privately owned, hotels in Scotland, each providing guests from around the world with an authentic and traditional Scottish experience.
Each hotel is unique, independently owned and distinctive in style, yet all offer the hallmark qualities of a warm Scottish Hotel; comfortable rooms, award-winning food and the personal attention of your hosts.
Our hotels are located throughout all areas of Scotland, from the Scottish Highlands and Islands to the Scottish Borders. You can search for hotels in Scotland by region via the locator map.
We have a wide range of short breaks available from romantic getaways to activity breaks such as golf or fishing breaks.
To book your stay at one of our hotels you can check availability and book online direct with the hotels own online booking system, alternatively you can simply fill in our quick enquiry form, this goes dierct to the hotels reception and someone will get back to you.
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Have a question, need some help with finding a hotel, please email Mark at email@example.com
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The Collingwood Arms Hotel
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Grade II Listed, luxury Georgian hotel set in glorious surroundings on the famous River Tweed. A perfect location for touring both sides of the border and Ideal for fishing, shooting, walking, horse riding and golf. For more ...view full property details
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Kukla's Korner Hockey
All Matt Duchene- Video Edition
by Paul on 09/28/10 at 05:38 PM ET
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Matt Duchene of the Colorado Avalanche has a chat with Scott Burnside of ESPN.
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Written on: 06/08/2014 by Kobeq290 (1 review written)
BEWARE, This company could effect your credit rating by their own mistakes.
After months of trying to sort a non delivery issue and asking for the account to be closed they still constantly chase us for the postage amount of this item that they have credited us for any way. Remittance can see the issue but cannot correct it, only customer rude services can, this morning I failed my name, date of birth, my address, or my home phone number that they rang me on in there account holder check and still we cannot resolve it. My credit rating has been clean for 10 years until this. NOT HAPPY!
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Forty years ago this fall, the halls of Butler High School were strangely silent.
As controversy swirls over President Barack Obama's planned televised speech Tuesday to students across the nation, local school districts are deciding how to handle it.
No free man is as closely watched by Hall County authorities as Michael Eugene Cromer.
The following are candidates for Northeast Georgia.
With all of the debates centering around proposed health care reform, it's hard for some people to determine what's truth and what's fiction - especially if they can't read the bill.
Longtime Gainesville school board member Kelvin Simmons may not be on the school board election ballot this fall because of a new state anti-nepotism law.
Professional wrestler A.J. Styles had a busy morning planned, between appearances on two TV sets and a lineup of speaking engagements - all before lunch.
A man who operated a crude methamphetamine lab inside a mobile home a few feet from where toddlers slept was sentenced to seven years in prison Friday.
The Labor Day holiday will have government offices throughout the area closed on Monday, but Hall County workers are taking an extra day off as well.
As the college football season ramps up, local business owners are counting on plenty of rambling and barking fans to ease their recession woes.
Chuck Westfall was named postmaster of Clermont, effective Aug. 29.
A skunk found in the Pea Ridge area of North Hall has tested positive for rabies, according to Gainesville-Hall County Animal Control.
Travel officials predict that Georgia's roads will be clogged with Labor Day holiday travelers, and area law enforcement agencies are preparing to handle the extra traffic.
A cramped South Hall trailer where three young children lived with their parents also was home to a toxic methamphetamine lab, a jury determined Thursday.
Georgia Power President Mike Garrett, directing the state's efforts to settle a water dispute with Alabama and Florida, said Thursday he was "guardingly optimistic that we can do a deal with Alabama."
Page 1374 of 1814
An argument in a Lula man's car preceded three gunshots to the chest and arms, a Gainesville Police investigator testified Thursday.
Braving winter weather
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Newfrontiers Bloggers is proud to welcome a new nation to the Newfrontiers worldwide community of bloggers - King's Church youth group from Christchurch, New Zealand. Please check out their blog and say hi.
If you know of other blogs not listed here or changes, please get in touch and let us know. Thanks
Week 21 miscellany: confusion at Man Utd, during graduation ceremonies, and in 30s and 40s - I went to an event at the Signet Library last week, it's very fancy. How crazy was Louis van Gaal at Manchester United? Not as crazy as Manchester United i...
7 hours ago


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Star Tracks
The Magic Mike hunk leads a flash mob in N.Y.C. Plus: Gwen & Zuma, Katy Perry, Kellan Lutz, Emma Stone and more
Credit: Richie Buxo/Splash News Online
Published: Wednesday Jun 27, 2012 | 05:00 PM EDT
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- Read the Cover Story: Steve Harvey: From Homeless to Having It All
- Search Continues for Missing Japanese Boy Abandoned in Mountains by Parents as 'Punishment'
- Johnny Depp Steps on Stage with Band in Germany Amid Amber Heard Abuse Allegations
- Who are the Hollywood Vampires: All About Johnny Depp's Band


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|Boxing Champions | Boxing Schedule | Boxing Video | Boxing History | Pound For Pound | Lounge | The Wire | Arcade
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No easy way out
Join Date: Jan 2010
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Man that movie sucked....
The hype for it was so ****ing humongous and it turned out to be nothing.
The problem was you don't find it out until the end.
The whole time you're expecting for something mind blowing to happy and nothing happens.
Stritctly UG's friend
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Time's a flat circle
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I liked it more than the first Alien movie. There, I said it.
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If the original Alien was produced today instead of 30years ago, it would have been an even bigger smash.
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But in Prometheus, they were very good. Maybe, the fact we didnt see too much of the Alien in the original movie added to the suspense. Like Jaws. If they had CGI back then they may have shown it too often, and sometimes the more you see, the less scary it becomes.
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Not sure why the black juice had different affect on the guy, seemed to change him into an engineer as to where he was more powerful. But on the girl the squid thing seemed to evolve from the snake thing that attacked the two idiots that got stuck in the cave. Also the black juice seemed like acid that burned helmet and face down but the other scientist was able to digest it and still impregnate a woman.
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Not bad but meh.
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Watched it yesterday... I was very entertained but was left with the same headscratchers as the rest of you.
Another interesting note. The engineeres made the base and created oxygen so they could breathe. Then how could the last engineer step outside of his crashed ship and get to the girl?
One thing I did love was that the film was stating the very act of refuting evolution and you can obviously see it happening with the Aliens. I think that was my favorite part.
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Home > News > Regional
< Back to SMG 45
Sunday, 2 March 2014 | MYT 7:02 PM
PHETCHABURI, Thailand: Thailand's first poll re-runs passed peacefully Sunday following a widely disrupted general election, as pro-government "Red Shirts" stepped up rallies in support of Prime Minister Yingluck Shinawatra's battered administration.
The February 2 election failed to ease a four-month political crisis when protesters seeking to topple Yingluck's government caused the closure of around 10 percent of polling stations, many in opposition strongholds.
The Election Commission said results cannot be announced until polls have been held in all constituencies, setting a late-April deadline for their completion.
Yingluck can only remain prime minister in a caretaker role until then with limited power over policy, further eroding her authority as she handles ongoing street protests and a series of legal challenges against her administration.
Election commissioner Somchai Srisutthiyakorn said around 120,000 people were registered to vote Sunday across more than 100 constituencies in five provinces.
He said the re-runs, the first attempted since February 2, had been held "peacefully... without any problems".
But only a trickle of voters were seen at several polling stations in Phetchaburi, an opposition heartland around 160 kilometres (100 miles) south of Bangkok, according to an AFP reporter.
"I was disappointed that I had the right to vote on February 2 but couldn't," Sangwan Yuusuk, 57, said at a polling station.
Under election law, 95 percent of the 500 seats in the lower house of parliament must be filled to enable the appointment of a new government.
On its website the Election Commission said senators will be elected on March 30.
The main opposition Democrat party, which boycotted the general election, last month lost a legal bid to nullify the poll.
In addition to the protests, Yingluck faces a series of legal complaints against her government, including charges of negligence over a troubled rice subsidy scheme which could see her removed from office.
Reds rally
Pro-government Red Shirts have ramped up their rallies and rhetoric in support of Yingluck and her billionaire brother Thaksin - a former prime minister who lives in exile to avoid jail for a corruption conviction.
Television footage Sunday showed thousands of people grouping in a car park in Khon Kaen - a Red Shirt stronghold in the country's northeast - for an overnight rally, wearing the ubiquitous red and waving flags.
It follows a similar rally on Saturday in the northeast, which together with the rural north has returned Shinawatra-allied governments to power in every election for more than a decade.
They say their votes are a political reward for policies that have funnelled state money to their hard-scrabble regions after years of neglect.
Opponents describe the same policies as a form of vote-buying.
"We are ready to come in Bangkok if the situation is still a mess," Red Shirt spokesman Thanavut Vichaidit told AFP, as he led a convoy of supporters to Khon Kaen.
Thailand has been riven by political divisions since 2006 when Thaksin was ousted in a bloodless military coup, sparking years of political turmoil punctuated by deadly street protests.
The worst violence left more than 90 people dead in the heart of Bangkok in 2010, in an army crackdown on Red Shirt rallies against the then-Democrat government.
Fears of widening civil conflict have surged amid gun and grenade attacks linked to the current rallies, which have killed 23 people - among them four children - and wounded several hundred others.
The violence prompted the head of the nation's coup-prone army to warn that Thailand could slide into civil war.
Anti-government protesters on Sunday began dismantling rally stages at several key intersections in Bangkok after announcing the end of a weeks-long self-proclaimed "shutdown" of the city.
Protesters, whose numbers have dwindled in recent weeks, have moved their tents to Lumpini Park in the city centre.
The movement has denied the retreat marks a defeat, saying it would keep up its struggle to overthrow a government that it sees as corrupt.
Despite their pullback, analysts say Yingluck's hold on power remains precarious, with anti-corruption authorities pressing charges over her role in the controversial rice scheme that could lead to her removal from office and a five-year ban from politics.
Some experts say that behind the scenes a power struggle is playing out to decide who will be in charge of the country when 86-year-old King Bhumibol Adulyadej's more than six-decade reign eventually ends. -AFP
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Injured Ledley named in Wales Euro 2016 squad
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text:
Research Article
The Potential Roles of Cell Surface pHs in Bioactive Peptide Activation
Version of Record online: 7 JUL 2014
DOI: 10.1111/cbdd.12374
© 2014 John Wiley & Sons A/S
Chemical Biology & Drug Design
Volume 85, Issue 2, pages 208–215, February 2015
Additional Information
How to Cite
Chen, L. and Liang, J. F. (2015), The Potential Roles of Cell Surface pHs in Bioactive Peptide Activation. Chemical Biology & Drug Design, 85: 208–215. doi: 10.1111/cbdd.12374
Publication History
- Issue online: 14 JAN 2015
- Version of Record online: 7 JUL 2014
- Accepted manuscript online: 13 JUN 2014 12:26AM EST
- Manuscript Accepted: 4 JUN 2014
- Manuscript Revised: 30 MAY 2014
- Manuscript Received: 16 APR 2014
Funded by
- NIH grant. Grant Number: GM081874
- Abstract
- Article
- References
- Cited By
- aggregation;
- cell surface pH;
- peptide;
- pH sensitive;
- self-assembly
Glycolytic metabolism of cells produces protons that are removed from the cytosol by transport proteins to create a pH difference between the adjacent bulk solution and the cell membrane surface. Therefore, tissue cells have distinct surface pHs because of varied glycocalyx and proton production capability. In this study, we proved the role of cell surface pH in peptide–cell interaction and peptide activation using lytic peptides with pH-dependent activity as probes. Properly, selected peptides could sense the specific pH zones on cells and thus demonstrated varied activity to tissue cells with different surface pHs. For a specific cell, the activity of pH-sensitive peptides changed accordingly as the cell surface pH was tuned up or down by proton channel regulators. Mechanistic studies revealed that cell surface pH directly affected peptide insertion into membranes by altering the secondary structure and aggregation status of membrane-bound pH-sensitive peptides. A pH-sensitive lytic peptide-designed based on the cell surface pH difference between a normal–cancer cell pair showed good selectivity to cancer cells. Therefore, cell surface pHs may present new opportunities to design therapeutic peptides with high cell specificity and selectivity.


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EgnsINVEST Ejd. Tyskland
Simmons First National Corporation
Simmons First Announces Second Quarter Earnings
PINE BLUFF, Ark., July 17, 2008 (PRIME NEWSWIRE) -- Simmons First National Corporation (Nasdaq:SFNC) today announced second quarter 2008 earnings of $6.0 million, or $0.42 diluted earnings per share, compared to $0.49 per share for the same period in 2007. "The decrease in earnings is primarily attributable to an increase in the provision for loan losses and a decrease in the premiums from the sale of student loans," according to J. Thomas May, Chairman and CEO. "The increase in provision for loan losses reflects our anticipated return to more historical levels, and a special provision related to our Northwest Arkansas region. Except for the special provision, second quarter earnings were very close to our expectations, and considering the challenges in the national economy and the banking industry, we are pleased with our earnings and asset quality."
Home BancShares, Inc.
Home BancShares, Inc. Announces Second Quarter 2008 Earnings
CONWAY, Ark., July 17, 2008 (PRIME NEWSWIRE) -- Home BancShares, Inc. (Nasdaq:HOMB) today announced second quarter earnings of $5.7 million, or $0.30 diluted earnings per share for the quarter ended June 30, 2008, compared to earnings of $5.1 million, or $0.29 diluted earnings per share for the same period in 2007. This represents a $593,000, or 11.7% increase in the 2008 earnings over 2007.


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Clipper Round the World Yacht Race - Race 10 re-start on hold
by Clipper Round the World on 18 Mar 2014
Race 10 re-start on hold as thick fog causes unsafe sailing conditions for fleet Clipper 13-14 Round the World Yacht Race
In the Clipper Round the World Yacht Race, the thick fog that caused Race 10 from Qingdao to San Francisco to be ceased yesterday shortly after it started, has gotten worse overnight with visibility currently down to just one boat length (70 foot).
Team Garmin skipper, Jan Ridd knows the course well having also skippered in the Clipper 2009-10 Race and explains the conditions the fleet are currently facing this morning: 'With visibility below 50 metres and an enormous amount of traffic, both cargo vessels and fishing fleets, we have spent most of the morning carefully navigating our way through the traffic.
'We could not have started a yacht race in these conditions, and also it would have been unsafe to bunch all the yachts together for a start with the density of traffic. We are nearly through the worst of the traffic but the visibility is worsening.'
Race Director Justin Taylor says: 'I anticipate that when the wind shifts to more from the west that it will improve and they can begin the Le Mans start. This is looking more likely to be first light tomorrow.'
Race 10 will see the Clipper Race fleet make their first Pacific Ocean crossing, where big seas and downwind conditions are expected to challenge the teams as they cover the 5,800 miles to the California Coast and the highly anticipated San Francisco Golden Gate Bridge finish line.
PSP Logistics will start Race 10 on Tuesday 18 March to provide more time for adequate yacht and crew preparation after its delayed arrival into Qingdao.
Stay tuned to the website and our Twitter feed for further updates to the Race 10
Clipper Round the World
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To commemorate the 100th anniversary of New York's 369th Infantry, join them for a documentary film screening of Men of Bronze (1977), a film about the remarkable African-American men who fought in WWI. Continue Reading →
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|By Business Wire
Article Rating:
|February 17, 2014 02:12 PM EST
Comcast is hosting two very special events this Saturday, February 22 for Jacksonville football fans, as part of the celebration of its newest Xfinity Stores that recently opened throughout the Jacksonville area. At the Jacksonville Jaguars Day events, fans will get the chance to meet, take pictures and get autographs from Jacksonville Jaguars players, cheerleaders and team mascot Jaxson De Ville.
On February 22 from 11:00am through 1:00pm, Jaguars linebacker Geno Hayes is appearing at the Pablo Creek Xfinity Store at 13740 Beach Boulevard. And Jaguars' tackle Cam Bradfield will be appearing on February 22 from 1:00pm through 3:00pm at the South Ortega Xfinity Store located at 6331 Roosevelt Boulevard.
These special fan events are part of the ongoing customer appreciation events in celebration of the opening of four new Xfinity stores in the Jacksonville area. These new stores are designed entirely around the needs of customers, offering consumers an opportunity to explore and interact directly with the latest Xfinity products and services. The new Xfinity stores in Jacksonville also include payment centers where customers can take care of their bill in a more welcoming, efficient and convenient environment.
At approximately 5,000 square feet, the Xfinity stores in Jacksonville feature fully interactive touchscreen displays, an Xfinity Experience Zone, customer lounge and seating area, a 3D TV viewing experience, a Kids Zone with iPads featuring child-friendly apps and content. The new store lets customers try out the newest Xfinity products and services, including the X1 Platform available now for Jacksonville customers. X1 is a first of its kind entertainment platform offering that offers a more personalized and dynamic TV experience. Customers can demo the Xfinity Home security control and energy management system, the Xfinity TV Go app, and the blazing fast Xfinity high-speed internet service. Small and medium-size business customers can learn more about Comcast Business products and services at kiosks throughout the store.
Customers will also appreciate the personalized service from trained and knowledgeable sales consultants and important new time-saving offerings, including a self-service kiosk for quick bill pay and a new queuing system that allows customers to explore the store at their own pace instead of waiting in line for service.
"Our new Jacksonville Xfinity stores provide a destination where our customers can not only experience our innovative products, but can take care of their business in a comfortable, interactive and entertaining environment," said Tom Zemaitis, Comcast's Regional Vice President of Sales and Marketing for Florida. "These stores were designed first and foremost with our customers in mind, to create an improved customer experience for them with the same mindset of innovation, speed and value that our customers love about our products."
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Become a fan of Comcast Florida on Facebook at www.facebook.com/ComcastFlorida and follow us on Twitter @ComcastFL.
About Comcast Cable
Comcast Cable is the nation's largest video, high-speed Internet and phone provider to residential customers under the XFINITY brand and also provides these services to businesses. Comcast has invested in technology to build an advanced network that delivers among the fastest broadband speeds, and brings customers personalized video, communications and home management offerings. Comcast Corporation (Nasdaq: CMCSA, CMCSK) is a global media and technology company. Visit www.comcastcorporation.com for more information.
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