text:
|By PR Newswire
Article Rating:
|November 7, 2012 05:30 AM EST
VIENNA, Nov. 7, 2012 /PRNewswire/ -- MOMENTUM 2012 --
News Summary:
- MRC Technology Selects EMC OnDemand, a private cloud deployment model for enterprise-class applications and enabler for accelerating customers' journey to the cloud
- EMC Documentum Platform OnDemand will enable MRCT to manage intellectual property and critical content related to advancing medical discoveries
- EMC OnDemand increases business agility, saves time and costs, and reduces risk
- EMC OnDemand customers can experience 30-60% reduction in total cost of ownership
Full Story:
At Momentum, the EMC Information Intelligence Group's EMEA user conference, EMC Corporation (NYSE: EMC) today announced MRC Technology, a healthcare technology transfer company and charity with its own drug discovery laboratories, has selected the EMC® OnDemand, a private cloud deployment model for enterprise-class applications. A fully-managed service, EMC OnDemand service enables MRCT to focus its resources on managing intellectual property (IP) and medical and scientific documentation, and not on maintaining the technology infrastructure required to support it.
MRCT is committed to translating cutting edge scientific discoveries into commercial products. The company adds value to the discovery process by working with companies, agencies and academic organizations for strategic patent protection and intellectual property licensing. Since its founding, MRCT has filed more than 300 patents, granted more than 400 licenses to its technologies, and generated licensing income in excess of 500 million Pounds Sterling for the UK's Medical Research Council, a government funded organization dedicated to tackling health problems.
MRCT uses the Documentum® OnDemand, EMC's managed hosting service to access, protect and manage the information that runs its business – its IP management, financial documentation and HR records. The repository is globally accessible, and the data center is hosted in Amsterdam.
The underlying technology of EMC OnDemand is a private cloud deployment model for enterprise-class applications, designed to help customers accelerate their journey to the cloud. Developed using a range of best-in-class technologies from VMware, RSA and EMC, the EMC OnDemand infrastructure enables quick provisioning and configuration for rapid deployment.
Customer Quote:
Gordon Bridges, Head of Information Communication and Technology, MRCT
"We understand the value of managing and protecting information, but the expertise required to run such enterprise-grade systems in house was not an option we wanted to pursue. EMC OnDemand allows us to focus our team and resources on other areas of value, providing the agility we need to grow. We integrated our hosted Documentum repository with our on-premise systems for true operational efficiency, and have found the EMC OnDemand service to work exactly as promised."
Follow EMC at Momentum:
- Discover all Momentum News
- Visit the EMC Community Network to follow the Momentum conference online
- Follow the @EMC_Momentum account and join the conversation using #mmtm12 on Twitter
- Stay connected with Momentum on Facebook, YouTube, and LinkedIn
Additional Resources:
- Learn more about EMC OnDemand
- Learn more about EMC Documentum Platform
- Join the EMC Documentum communities on Twitter, Facebook, YouTube, SlideShare, the EMC Community Network
About MRC Technology
MRC Technology is a technology transfer company responsible for adding commercial value to cutting edge scientific discoveries through strategic patent protection, creative licensing of intellectual property (IP), partnered research or further scientific development.
As well as offering technology transfer services to the UK's Medical Research Council the Company has recently broadened its activity to include helping other charitable and academic organisations (such as AICR) with IP management and commercial development of healthcare-related science, thus bringing valuable income back to the organisations to help fund further research.
MRC Technology also has small molecule drug discovery and therapeutic antibody facilities, providing lead-stage therapeutic assets to pharmaceutical and biotechnology companies.
About EMC
EMC Corporation is a global leader in enabling businesses and service providers to transform their operations and deliver IT as a service. Fundamental to this transformation is cloud computing. Through innovative products and services, EMC accelerates the journey to cloud computing, helping IT departments to store, manage, protect and analyze their most valuable asset — information — in a more agile, trusted and cost-efficient way. Additional information about EMC can be found at www.EMC.com.
EMC, Documentum, are registered trademarks or trademarks of EMC Corporation in the United States and other countries. All other trademarks herein are the property of their respective holders.
SOURCE EMC Corporation
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Zachary Holmes
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Megan Gallagher
From being a member of the Redcoat Marching Band to serving on University Council to immersing herself in research, Megan Gallagher, a senior in social work, says her time at UGA "has been an incredible experience in every way."
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subset: commoncrawl


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Hurricane White's Scary Stereotyping, a favorite attraction of Jules Verne
Enjoy a trip simulating the scary halucinations and elating electrocutions from Hurricane White's legend. Invade the eight miners' cave, the haunted woods, and the sauna of the Conceited Witch's man cave. But don't worry -- it will all end up terminally ever after!
We suggest you don't try Princess Mode
© copyright 2011–2016
A Pants Aflame production


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Chapel Hill, North Carolina Patents Lawyers and Law Firms
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|» Step 2: Provide Contact Information & Submit
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HOUSTON – It was a dreadful performance, just dreadful, and yet after it was over, the Houston Rockets were smiling.
A 100-95 victory over New Orleans meant the Rockets kept their position as the eighth seed in the Western Conference, and perhaps ended the Pelicans' chances of reaching the postseason.
In the process, the Rockets made just 3 of 34 shots from 3-point range. Yes, the Rockets set an NBA record by making just 8.8 percent of their 3-point attempts.
This from a team that set the NBA single-season record for 3s last season.
The 31 misses tied for the most in a victory in the past 30 years. It's happened just five times in league history, with Golden State doing it twice last season.
Dreadful, just dreadful.
"We were trying to figure it out if [3-of-34] is the record in a win," said a smiling J.B. Bickerstaff, the Rockets' interim coach, who was just happy to snag a victory. "There were open shots, too. We had a ton of open looks. Those are shots we work on everyday, and to be able to win a game when you shoot eight percent from the 3-point line and turn it over 21 times. There is something we must have done right."
The Rockets missed their first 15 3-point shots and then made two of their next three. Another poor run, 15 consecutive misses, ended when Patrick Beverley knocked down a 3 with 51 seconds remaining to give Houston a 97-95 lead.
Beverley's 3 was set up by James Harden bringing the ball up the floor and finding his man 23 feet out when the Pelicans clogged the paint to try to stop The Beard from driving.
"I saw Anthony Davis closing out on him for the block and Anthony Davis closed out on me again," said Beverley, who missed 4-of-6 from long range. "I just tried to get it up and it went in. You got to give James credit. Defenders always watching him and he made an easy pass play."
The Rockets went 10-for-37 on uncontested shots, with Jason Terry missing four uncontested jumpers, Corey Brewer missing 4-of-5 when alone and Trevor Ariza misfiring on 6-of-8 such shots. Beverley said he has never seen Terry miss that many open looks in his career.
Houston has Harden to save itself. He scored a game-high 39 points in another heavy-minutes night (40) in which he added 12 rebounds, seven assists and four steals. He also committed eight turnovers, most on drives to the basket and on passes, as the Pelicans tried to take him out of the game with double-teams and physical play near the basket.
Harden made 7 of 16 contested shots and was the lone Rockets player to have a nice evening making uncontested shots, going 4-of-8. And with the 3-point shot failing, the Rockets did make 70.2 percent of their 2-point field goal tries, the fourth-best mark this season.
Four other NBA teams won Wednesday night while shooting less than 30 percent from 3-point range. So it can't be all bad.
"It really wasn't frustrating. I think ultimately we played extremely hard," Harden said. "Three-for-34, that's rarely going to happen -- if we knock down 10 of those 3s, it's a different ballgame. We just got to continue to fight through it and grind the game out."


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Schools are teaching pupils all
they need to know about the
biology of sex but place little
emphasis on the importance of marriage
and loving relationships, Ofsted
inspectors warn today.
Sex education lessons are marred by
teachers' embarrassment and a
failure to discuss the possibility that you
can 'say no' to intercourse.
One in three secondary schools is failing to provide good quality teaching in personal, social, health and economic education (PSHE) which includes lessons on sex, drugs and alcohol, Ofsted warns in a report.
Sex education lessons are marred by teachers' embarrassment and a failure to discuss the possibility that you can 'say no' to intercourse
Inspectors criticise a failure in many
schools to consult parents about the
content and timing of lessons despite their
sensitive nature.
Some lessons used 'inappropriate resources' and failed to match work to pupils' maturity, suggesting some are exposed to materials too advanced for their age.
Ofsted suggests that schools use
storylines from popular TV dramas
as a starting point for some
Pupils may need help to
'make sense of ' sensitive scenes
they have seen, it is claimed.
One in five sexually-active teenage girls has been pregnant by the age of 18, shocking figures revealed yesterday.
The first survey of its kind found that 83 per cent of girls have lost their virginity by this age and 18 per cent of these youngsters have been pregnant at least once.
About half chose to keep their babies and more than a third had an abortion, according to the Government survey. A further 18 per cent reported having had a miscarriage.
Incredibly, more than 1,300 18-year-old girls have been pregnant three times.
Previous research has shown that girls feel they are under increasing pressure to have sex before they are ready, partly because of sexy images projected in marketing and teen magazines.
The statistics from this latest study show more than a quarter of girls said they had not waited until the age of consent and 27 per cent of 4,298 girls questioned for the study had lost their virginity by the time they turned 16.
The data once again reignites the controversy over Britain's teenage pregnancy rate, which is the highest in Western Europe, and Labour's decade of failure to tackle the problem.
Figures released earlier this year revealed there were more pregnancies among girls under 18 in England in 2008 than there were in 2001.
Family values campaigners have long warned that easy access to contraception and poor quality sex education which fails to encourage teenagers to say 'no' are fuelling the problem.
The survey shows how education plays an important role for youngsters as they are significantly less likely to have been pregnant by 18 if they did well at school and their parents have degrees.
Children who live with both parents are half as likely to engage in underage sex according to the study, published by the Department for Education.
The research relied on girls answering truthfully and there is no way of verifying their responses.
Many teachers are too
embarrassed or lack the necessary
knowledge to teach sex education convincingly-One teacher wrongly
believed that all changes during
puberty took place between the
ages of 12 and 16.
Some lessons
were 'dull' and 'superficial' and
relied mainly on worksheets.
In good schools, most students had a 'secure knowledge' of contraception and preventing sexually-transmitted diseases, but struggled to discuss other issues.
'To a lesser extent, the students were able to identify and discuss relationships – marriage, parenthood, same-sex relationships and family life – and how these could have an impact on their lives.
'Students' knowledge and
understanding was often good about the
biology of sex but weaker about
relationships,' the report says.
It adds: 'Discussion was
sometimes limited because of the teacher's embarrassment or lack of
'In these schools, the students did not have the opportunity to explore the nature of relationships in any depth.
'They had not discussed managing risks, saying no, negotiation in relationships, divorce and separation or living in reconstituted families.
'Pupils' understanding of sex education was merely satisfactory or weak in more than one in three secondary schools, the report warns.
In primary schools, sex education
was too often 'squeezed out' or left
until after spring SATs tests in
pupils' final year, leaving them with
only a 'partial understanding' of
One in seven primaries was failing to offer good teaching in PSHE.
In a further finding that will alarm
parents, Ofsted said that in 165
primary and secondary schools
visited, 'parents were rarely involved
with or consulted about PSHE
The report went on to raise concerns about drug and alcohol education.
In half of secondary schools visited, pupils' knowledge of the physical effects of alcohol was 'rudimentary'.
Some teachers failed to reinforce that buying alcohol was against the law for under-18s or challenge pupils' boasts about under-age drinking.
Pupils were frequently unaware of
the long-term consequences of drug
and alcohol misuse.
Meanwhile lessons in personal
finance, added to the PSHE
curriculum in 2008, were 'not yet well
established' in many schools.
Ofsted chief inspector Christine Gilbert said 'schools should continue to promote professional development in PSHE education so that teachers strengthen their knowledge and skills'.
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You are here: Homepage » North Carolina » Eden
Plumbers in Eden
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Professional Recognition is a means for teachers in Scotland to engage with Professional Enquiry at a master's level in pedagogical or subject specific areas. Our year-long programme will allow teachers to gain Professional Recognition in an area of expertise which is accredited by Primary Engineer and moderated by the GTCS (General Teaching Council for Scotland). The programme is funded by Skills Development Scotland.
If you have taken part in a Primary Engineer training day you can undertake the Professional Rcognition for free. If you would like to find out more about the programme click on the link below.


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دانلود کلیپ سکسی خفن ایرانی زوری سکس کلیپ های گلشیفته فراهانی While operating on a mythic level �Honeydripper� also wants to create the same kind of top-to-bottom social microcosm found in many of Mr. کلیپ سکس کامل Sonny, an unknown, is passed off as Guitar Sam, a regional blues legend who is a last-minute no-show at the Honeydripper.
دانلود فیلم سوپرخارجی Criticism of his durability intensified when he damaged his knee ligaments while scrambling for a touchdown against the Minnesota Vikings. دانلود فیلم سوپرخارجی While the paper does not indicate the source of the image, Thai police say they believe it is a picture of Carradine`s body taken by a forensics team that examined the Bangkok, Thailand hotel room where his body was discovered last week.Grossman was criticized when he threw a game-ending interception against the Detroit Lions on opening day. دانلود کلیپ سکسی خفن ایرانی زوری سکس Lucky for him he�s resilient and he came back and led us to two scoring drives. کلیپ سکس کامل Jagged Edge, made a lasting impression on Top 10 music charts nationwide and has even earned her a Grammy nomination.
Adam Holland is a DTV answer guy and is offering information at kiosk at Southridge Mall. کلیپ های گلشیفته فراهانی It is possible that the autopsy and death scene photos will be published in Thai paper, sure to cause more frustration to an already grieving Carradine family. کلیپ های گلشیفته فراهانی We`re not pitching you anything.`` He`s giving free information about the conversion from analog to digital television, courtesy of the Federal Communications Commission.``If I didn`t do it, I would`ve been dead,`` she told The Post.


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Articles tagged romany malco
20 Jun 2008 // 2:00 AM
Both frantic and tedious, The Love Guru piles on the slapdash offenses.READ more
It stands as one of the most unusual, and blinkered, boycotts ever. For the last few months, self-proclaimed Indo-American leader Rajan Zed has been wagingREAD more
28 Apr 2008 // 10:59 PM
If May almost tent-poled itself out of existence, June will be even worse. After all, are audiences really ready for 13 major release in less than two months -- with more to come?READ more
If he's not precisely magical in Baby Mama, Oscar (Romany Malco) does function as wise advisor for white women who should know better.READ more
Once more, Mom slips into her "Godmother" persona, wades into the tall weeds of moral ambiguity, ready to make one more compromise, one more sacrifice.READ more
26 Aug 2005 // 1:00 AM
Here, a one-note title evolves into a 3-D landscape of guffaws and awws.READ more
Hazmat Modine "Moving Stones" (video) (premiere) // Music
Derik Hultquist "My New Orleans" (audio) (premiere) // Music
Super Furry Animals "BingBong" (Singles Going Steady) // Music
Jodie Foster's First Great Performance: 'The Little Girl Who Lives Down the Lane'
// Short Ends and Leader
"Why has this low-budget Canadian-French production flown under the radar?READ the article


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Báo Tuổi Trẻ English 1 day(s) ago
LONDON, May 24 - English soccer's biggest club seem to have secured the services of the sport's most colourful manager after Jose Mourinho, according to Sky TV reports, agreed personal terms with Manchester United on Tuesday.
Keywords: MourinhoChelseaFa CupManchester UnitedPremier LeagueJose MourinhoManager
Báo Thanh Niên English 4 day(s) ago
Iraq's army said on Sunday it was preparing to retake the Islamic State stronghold of Falluja and asked residents to get ready to leave, state TV reported.
Keywords: retakeleaveThe IraqiPreparingAl Qaedastatetank
Báo Thanh Niên English 6 day(s) ago
Greek aviation officials say a missing EgyptAir passenger plane with 66 people on board made a sharp swerve in mid-air before disappearing from radar view. Greek TV says plane debris has been found.
Keywords: viewsaypeople
Báo Thanh Niên English 7 day(s) ago
The Authority of Broadcasting and Electronic Information has issued fines totaling VND171 million (US$7,680) against military-run telecom group Viettel for multiple violations in broadcasting.
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Báo Tuổi Trẻ English 1 week(s) ago
Vietnam's state broadcaster has issued a public apology and suspended one of its reporters for fabricating a TV report accusing farmers in a northern province of using dishonest tricks to grow pesticide-free vegetables.
Keywords: VegetablesreportHuongConsumerslookVietnam Television
VietStock FI English 2 week(s) ago
Cambodia based telecommunications and media consultancy Star Digital MUDS TV Co Ltd signed an MoU with Huawei Technologies – a Chinese networking and telecommunications company – yesterday in a move to launch 4G services in the Kingdom.
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Báo Tuổi Trẻ English 2 week(s) ago
A number of Vietnamese dramas will start broadcasting on Myanmar's MW television channel next month.
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Báo Thanh Niên English 1 month(s) ago
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K+, a pay TV joint venture between national broadcaster VTV and France's Canal+, has obtained the rights to broadcast the English Premier League in Vietnam after a group of local networks failed to strike a deal.
Keywords: broadcastRightspaySubscribersdealNetworksThe English Premier League
Báo Đầu Tư English 1 month(s) ago
As the Korean wave continues to spread across Asia, its latest drama series Descendants of the Sun (Hau due mat troi) has gained popularity among young people in several Asian countries. The drama has recently fallen into controversy after a Vietnamese TV channel announced it would broadcast it.
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Báo Dân Trí English 1 month(s) ago
State-owned Vietnam Television (VTV) may divest from K+ paid TV following continuous losses at the satellite TV service.
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Vietnam Television (VTV), which represents the state capital in Vietnam Satellite Digital Television (VSTV) - the joint venture with French pay TV operator Canal+ Group, said it may have to ask for permission from the prime minister to sell its stake, according to newswire vneconomy.vn.
Keywords: LossesleftreportventureCompetitorssellImages
Báo Thanh Niên English 1 month(s) ago
National broadcaster Vietnam Television plans to sell part of its stake in a pay TV joint venture with France's Canal+ Group after the six-year-old business piled up nearly VND2 trillion (US$88.52 million) in losses, local media reported Wednesday.
Keywords: Vietnam TelevisionSubscriberspayLossessell
Vietnam Satellite Digital Television (VSTV), the joint venture between state-owned broadcaster Vietnam Television and French pay TV operator Canal+ Group, would incur huge losses if it's unable to buy the rights to broadcast the English Premier League (EPL) for the 2016-2019 period.
Keywords: RightsbroadcastbuyindividuallyLossesNegotiatingdocument
Báo Tuổi Trẻ English 1 month(s) ago 1 duplicate news
A charity TV show aimed at helping needy farmers in Vietnam has found a new host, after the former one Minh Beo was arrested on child sex charges in the U.S last month.
Keywords: hostThe ShowControversy TheChargesThe U SHouseholdsThroughout Vietnam
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Washington: A new study involving an Indian-origin researcher has suggested that taking a cholesterol-lowering drug called statin before having major elective surgery could potentially reduce serious kidney complications.
Each year, more than 230 million major elective surgeries are performed around the world. Unfortunately, many patients who undergo major operations develop kidney injury soon after surgery, often due to decreased blood flow to the kidneys and/or the effects of inflammation.
Animal studies suggest that statins protect the kidneys from such damage, but whether a similar benefit occurs in humans is uncertain.
To investigate, Amber Molnar, (University of Western Ontario and Lawson Health Research Institute, in London, Canada), Amit Garg, (University of Western Ontario and Lawson Health Research Institute, in London; and the Institute for Clinical Evaluative Sciences, in Toronto, Canada) and their colleagues conducted a population-based retrospective study of all older patients who underwent major elective surgery in the province of Ontario, Canada from 1995 to 2008. Surgeries included cardiac, thoracic, vascular, intra-abdominal, and retroperitoneal procedures.
A total of 213,347 patients from 211 hospitals underwent major elective surgery, and 4,020 patients (1.9 percent) developed postoperative kidney injury within two weeks of surgery. A total of 1,173 patients (0.5 percent) required dialysis within two weeks of surgery, and 5,974 patients (2.8 percent) died within a month of surgery.
Prior to surgery, 67,941 patients (32 percent) were taking a statin. Patients taking a statin were 20 percent less likely to develop kidney injury, need dialysis, and die compared to patients who were not taking a statin. Also, there was evidence of a dose-effect, with patients on higher potency statins having less kidney injury. In addition, statins were beneficial whether they were started greater than 90 days or less than 30 days prior to surgery.
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ABS continues to cultivate industry expertise for the development and modification of Rules and Guides with the formation of The Offshore Technical Committee of ABS.
"ABS once again has taken the lead in working with the offshore industry," said ABS President and CEO Christopher J. Wiernicki. "The Technical Committee of ABS has advised us for many years. The recent division of the committee into Offshore and Marine allows each group to concentrate more fully on its specific area of interest."
The goal of the recent division of The Technical Committee of ABS into separate committees was to refine the focus of each committee to facilitate information exchange for Rule and Guide development and modification. ABS is the first class society to take this approach.
The first meeting of the The Offshore Technical Committee, hosted 3-4 May 2012 in Houston, was attended by a majority of the 40 members elected by The Council of ABS. Attendees included designers, builders, owners, operators and regulators of offshore assets.
The agenda for the inaugural meeting included a review of ABS proposed rule changes followed by a discussion on topics of interest raised by the attending industry experts. The advice garnered from the Committee's discussions will be referred to the Rules Committee of ABS.
"The first meeting of the The Offshore Technical Committee demonstrated that we have made an excellent decision in separating the Marine and Offshore groups," said Todd Grove, ABS Chief Technology Officer. "The value of the feedback on our Rules clearly demonstrates the focused expertise of our members."
The Offshore Technical Committee is scheduled to meet on an annual basis as part of the ongoing ABS rule development cycle, but as technical topics surface during the intervening months, ABS will interface with the committee to gather valuable input.
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Hercules Offshore Inc said it planned to file for prepackaged Chapter 11 bankruptcy, just six months after the rig contractor emerged from bankruptcy protection.
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Home / Meat and Poultry / Can someone tell me what are Protein foods?
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Home > News > World
Sunday, 20 July 2014 | MYT 9:45 PM
KIEV (Reuters) - Twenty-seven more bodies have been found on Sunday along with 20 fragments of bodies at the site where a Malaysian airliner crashed, Ukrainian Deputy Prime Minister Volodymyr Groysman said.
He told a news conference that the bodies of 192 of the 298 people killed when the plane plunged into the steppe in eastern Ukraine on Thursday had been placed in refrigerated train wagons before being sent home for burial.
(Reporting by Natalia Zinets, writing by Elizabeth Piper, editing by Dale Hudson)
Trump, aiming to offset money disadvantage, escalates Clinton attacks
Belgian police detain four on suspicion of belonging to terrorist group
U.N. concerned by rising political tension in Congo ahead of vote
Former Canadian PM Harper to leave politics, reports say
For a hopping great time where else but Kangaroo Island!
Astoria strikes a balance
Tourism M'sia chairman denies causing ruckus at China expo
Puteri Umno members to serve in Sungai Besar parliamentary by-election campaign
Atletico fitter and wiser as they plot revenge for Lisbon
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Wednesday 14th May, 2014
On the last day of this year's Great Escape Festival Robert Luis sat down with CMU editor Chris Cooke for a chat on 'Running A Record Label'. Hear the whole thing in full below.
Read more about it on the CMU website.
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PEOPLE ARE SAYING "i think you need to make a sequel or another one" WELL PEOPLE THERE IS IT IS CALLED BREAKING THE BANK THAT ONE IS TOO SHORT LIKE THIS ONE BUT FOR THAT ONE IS THE SEQUEL ESCAPING THE PRISON THAT ISNT SHORT
thank you for reading i dont wanna say everybody is dum or that im angry... :D but just too help
Yeah no worries. The sequel to Escaping the Prison will be even longer!
black and white - no textures, and too short. But fucking awesome hilarious! Concepts were fantastic - now find and artist who can help you nail a perfect style
Except this is like 5 years old now and I've improved greatly.
mass over kill!!!!!
OMG it was so funny. I loled so hard.
That poor guy(I call him E.F.M Epic Fail Man) he just can't win.
the cannon was probably my faverite. You know for the pole vault/ ramp you think he would've taken the time too measure.
How would he measure if he can't get to the other side? ;)
wow.....he just can't seem to get the hang of that teleporter huh.
Nope, but to be fair it's pretty complicated. It's a teleporter after all.
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The dogs in the Hall County Animal Shelter got a good night's sleep Friday.
Gainesville First United Methodist Church could be Eagle Scout central on Sunday.
When it comes to being a parent, most will do anything to guarantee the happiness of their children.
During years of extreme-drought conditions, most wished for more water. Now that the water has come, some local residents are wishing for less as it has caused more than a couple of problems along some area roads.
The National Weather Service in Peachtree City has issued a winter storm warning for the Gainesville area.
A rabies alert has been issued for East Hall County after a rabid raccoon was confirmed in the area this week.
Gainesville officials are looking to keep skateboards off the downtown square and the city's new downtown parking deck.
Dawson County's longtime clerk of Superior Court has been charged in connection with the theft of more than $119,000 from the county over the last five years.
The Hall County Board of Commissioners decided to go back to the drawing board on two important issues Thursday after taking heat from residents at both ends of the county at its packed board meeting.
In times when some Hall County schools have had trouble just keeping office supplies in stock, West Hall Middle School decided not to go down without a fight - or at least a wrestling match.
The aroma of Haitian dishes on Thursday night wafted across the lobby of the Brenau University's John W. Jacobs Jr. Building.
Gov. Sonny Perdue on Thursday signed a bill authored by local state Rep. James Mills.
A missing Blairsville woman's mother has taken to YouTube with a plea to the writer of an anonymous letter.
Oakwood City Council has approved ornamental street lights for Thurmon Tanner Parkway's final stretch, which is set for a December completion.
JEFFERSON - After months of postponing action, the Jefferson City Council approved a rezoning request from First United Methodist Church of Jefferson during a special called meeting Wednesday.
Page 1275 of 1814
Braving winter weather
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Cross-Region Replication Using DynamoDB Streams
DynamoDB cross-region replication is a client-side solution for maintaining identical copies of DynamoDB tables across different AWS regions, in near real time. You can use cross-region replication to back up DynamoDB tables, or to provide low-latency access to data where users are geographically distributed.
Cross-region replication supports a single-master model. In this model, you create a master table with DynamoDB Streams enabled, and one or more replica tables. Each replica can reside in a different AWS region. When you modify data in the master table, the cross-region replication solution transparently updates all of the replicas, so that all of the tables in the replication group are kept in sync.
The replica tables are intended to serve as read-only copies of the data; however, it is possible to write data to a replica table. If you write data to a replica, those changes will not be propagated to the master, or to any other replicas. In addition, if you modify an item in the master table, that item will overwrite the same item in all of the replicas.
The following diagram provides an overview of a cross-region replication setup.
Cross-Region Replication Overview
You launch a preconfigured AWS CloudFormation stack. This is a one-time operation that takes approximately 20 minutes to complete.
The AWS CloudFormation stack uses AWS Elastic Beanstalk to launch the Replication Coordinator and DynamoDB Connector into the Amazon EC2 Container Service (Amazon ECS).
You use the Cross Region Replication Console to create a replication group.
The Replication Coordinator allocates all of the necessary resources, including metadata tables and replica tables in other regions. This operation can take up to 30 minutes to complete.
The DynamoDB Connector reads and processes incoming records from the stream on the master table in DynamoDB.
The DynamoDB Connector updates the replica table(s).
After the initial setup, the following components are used to perform the replication tasks.
Cross Region Replication Console—a standalone web application that resembles the AWS Management Console. This application allows you to:
Define a replication group, consisting of a master table and at least one replica. The master and the replica(s) must have the same key schema and attribute definition. A replica can be located in the same AWS region as the master, or in a different region.
Launch the replication group. The Cross Region Replication Console communicates with the Replication Coordinator to perform create, delete, and update operations for the replication group.
Monitor the performance of replication groups and their members.
Add and remove replicas from a replication group, or delete a replication group.
Replication Coordinator—an application running on Amazon EC2 Container Service that does the following:
Responds to user requests from the Cross Region Replication Console.
Manages replication states and physical copies of a table.
Creates and maintains the following DynamoDB tables:
One metadata table that keeps track of replication activity and enables recovery from failures.
One KCL checkpoint table for tracking Kinesis Client Library (KCL) processing.
An additional KCL checkpoint table per replication path. For example, if you have a replication group with three replicas, the Replication Coordinator will create three additional KCL checkpoint table. Each additional KCL checkpoint table is created in the same AWS region as its corresponding replica.
Amazon Web Services provides a prewritten AWS CloudFormation template that launches the Replication Coordinator on a customer-provided Amazon ECS cluster.
DynamoDB Connector—an application that contains the low-level processing logic for replication from a source table to a destination table. The DynamoDB Connector does the following:
Reads incoming DynamoDB Streams records for the source table, using the Kinesis Client Library (KCL) and the DynamoDB Streams Kinesis Adapter libraries.
Analyzes each stream record to determine whether that record is necessary for the current replication tasks.
Groups related stream records into batches, based on primary key values. Duplicate stream records are removed.
Issues asynchronous conditional write requests to the replica table, in parallel.


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L e t t e r s t o t h e E d i t o rCombined18F-FDG and Fluoride Approach inPET/CT Imaging: Is There a Clinical Future?TO THE EDITOR:by Iagaru et al. (1) that examined the feasibility of combined18F-FDG and18F-fluoride PET/CT in the management ofpatients with cancer. We congratulate the authors for theirwell-conducted study and would like to share our views on thispromising approach. As mentioned by the authors, Hoegerleet al. (2) previously explored a similar approach with PETmethodology in a prospective study that investigated 30patients with various malignancies who underwent combined18F-FDG and18F-fluoride PET. The result was compared withthat of the control group comprising 30 patients whounderwent only18F-FDG PET. These authors concluded thatcombined18F-FDG and18F-fluoride PET is an advancedmetabolic imaging approach for the evaluation of cancer.There are certain obvious methodologic differences betweenthe previous study and the present one: The previous studyadopted PET, which was the predominant modality at thattime, whereas the present study used PET/CT fusion imaging.In the present study, the same patients underwent separate18F-fluoride PET/CT and18F-FDG PET/CT and combinedFDG–18F-fluoride PET/CT scans; that is, a total of 3 scanswere performed on each patient, whereas in the previous study,2 different patient groups were tested with 2 different scans.Though the first study was conducted in 1998, there wasapparently no further endeavor until the present study, a decadelater, to investigate the potential of this 2-in-1 dual-tracerapproach to PET.This thought-provoking approach raises certain importantquestions in a logical mind with regard to clinical applicability.The foremost obvious question is what the potential clinicalindications will be for this approach. Defining the clinicalsituation in which the combined study will be of advantageover conventional18F-FDG PET/CT or thetechnique appears to be of great importance. One can foreseepromise for skeletal metastatic lesions, an application in which18F-FDG PET demonstrates limited sensitivity. This applica-tion would include detection of osseous metastatic lesions inmalignancies such as prostate or thyroid carcinoma. However,one must be aware of certain practical issues that might beassociated with the combined18F-FDG–18F-fluoride approach:first, one must remember the great potential of18F-FDG indetecting and evaluating marrow metastases—a potential thatrivals MRI in this context (3). It is perceivable that thisadvantage of18F-FDG might be compromised in the combined18F-FDG–18F-fluoride approach when there is normal skeletaluptake of fluoride that can obscure an abnormal18F-FDG–avidfocus in the bone marrow. Also, as observed in this pilot study,therapy with bone marrow–stimulating agents can induceintense18F-FDG uptake in the skeleton that can hamper theinterpretation of18F-fluoride uptake. In addition, after admin-istration of systemic or hormonal therapy, the osseous flareWe read with interest the recent article18F-18F-fluoridewith18F-fluoride may prove to be a confounding factor in theassessment of therapeutic response in18F-FDG–concentratingskeletal lesions. The metabolic flare withsystemic or hormonal therapies, on the other hand, is relativelyshort-lived and is an advantage in treatment monitoring with18F-FDG PET (4). These factors are important in routineclinical PET and must be considered before this approach canbe recommended in this scenario. As the authors rightlyindicate, the use of skeletal18F-fluoride uptake as a surrogatefor anatomic localization of an abnormal focus of18F-FDG isno longer valid in the present era of PET/CT fusion imaging.The above having been said, the combined approach, if usedappropriately, can be of substantial value in certain specificsituations, and these potential clinical indications for thispowerful technique must be defined precisely by the usercommunity to render this approach clinically viable andefficient.18F-FDG afterREFERENCES1. Iagaru A, Mittra E, Yaghoubi SS, et al. Novel strategy for a cocktail18F-fluorideand18F-FDG PET/CT scan for evaluation of malignancy: results of the pilot-phase study. J Nucl Med. 2009;50:501–505.2. Hoegerle S, Juengling F, Otte A, Altehoefer C, Moser EA, Nitzsche EU.Combined FDG and [F-18]fluoride whole-body PET: a feasible two-in-oneapproach to cancer imaging? Radiology. 1998;209:253–258.3. Basu S, Torigian D, Alavi A. Evolving concept of imaging bone marrowmetastasis in the 21st century: critical role of FDG-PET [editorial]. Eur J NuclMed Mol Imaging. 2008;35:465–471.4. Basu S, Alavi A. Defining co-related parameters between 'metabolic' flare withthose of 'clinical', 'biochemical' and 'osteoblastic' flare and establishingguidelines for assessing response to treatment in cancer. Eur J Nucl Med MolImaging. 2007;34:441–443.Sandip Basu*Ramesh Rao*Radiation Medicine Centre (BARC)Tata Memorial Hospital AnnexeParel, Bombay 400012, IndiaE-mail: firstname.lastname@example.com: 10.2967/jnumed.109.066860TO THE EDITOR:tains a paper on the combined use of18F-FDG and18F-fluoridefor dual detection of soft-tissue and skeletal metastatic disease(1). There are 2 comments that I feel should be made about thispaper.First, the authors state ''Combining18F and18F-FDG in a singlePET/CT scan for cancer detection has not been reported to date.''Although it is technically true that this is the first paper to bepublished that has reported combined18F-FDG and18F-fluorideimaging with a combined PET/CT scanner, it is slightlydisingenuous not to mention until well into the ''Discussion''section of the manuscript that these agents have been used inThe April 2009 issue of the journal con-COPYRIGHT ª 2010 by the Society of Nuclear Medicine, Inc.LETTERS TO THE EDITOR165
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