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Developmental Regulation of Human Embryonic Stem Cells by microRNAs
Stem cells are remarkable cells which have two unique properties: self-renewal (self replication) and pluripotency (the ability to regenate a wide range of tissue-specific cells). These properties and the associated potential to use these cells to cure a wide range of degenerative diseases such as Alzheimer's Disease, Parkinson's Disease, and heart disease, have made stem cells a subject of intense scientific and medical interest. The recent discovery of cancer stem cells implies that stem cell research will also have important implications for cancer therapy, since cancer stem cells must be targeted by cancer drugs to prevent relapse of tumors.
The mechanisms by which stem cells self-renew and differentiate are poorly understood. Several genes have been isolated and are thought to be essential to mammalian stem cell renewal and differentiation. Recent evidence has identified a new and potentially important molecular mechanism for regulating these genes in ESCs. These molecules are small bits of RNA, of approximately 22 nucleotides (nt) in length, and often termed microRNAs (miRNAs).
miRNAs appear to play an important part in regulating gene activity. These small RNAs "turn off" genes by directly binding to them and preventing the production of proteins based on the gene's genetic code. Several recent studies indicate that the types of miRNAs present in stem cells (miRNA "expression profiles") are different from other cells and tissues. We propose to identify candidate miRNAs that are playing key roles in hESCs and to characterize the effects of their actions on self-renewal and differentiation.
Our preliminary data also indicates that miRNA "expression profiles" differ depending on whether a stem cell is differentiating, self-renewing, or quiescent. This project will employ a wide range of techniques in molecular biology, including microarrays, bioinformatics, and bioluminescent reporter gene assays, to determine which specific miRNAs show differential expression between stem cell states and we will identify the genes they target.
Having identified candidate miRNAs that play an important role in determining stem cell fate, we will manipulate their expression levels using biotechnology techniques known as RNA oligos and plasmid or viral expression vectors. We will then determine if these manipulations change the cell's decision-making process in regard to differentiation or self-renewal. This will be done using molecular biology and biochemical assays on undifferentiated and differentiated cells.
Ultimately we will investigate the underlying regulatory mechanisms in hESCs that control miRNA expression. We anticipate that our results will contribute to understanding the transitions between stem cells and differentiated cells, as well as normal and cancer cells. This type of information can be invaluable in designing new therapeutic approaches for stem cell replacement or cancer treatment.
Human embryonic stem cells (hESCs) hold the potential to revolutionize human medicine by making cell replacement therapies, drug delivery, or in vivo modifications of cell populations a reality. In degenerative conditions we may be able to replace dead cells with functional new ones derived from hESCs. This approach could be used to treat Parkinson's Disease, Alzheimer's Disease, heart disease, diabetes, or paralytic spinal cord injuries. There is also potential for new cancer treatments, as cancer stem cells share many properties of hESCs.
This type of medical technology would benefit the citizens of California in several general ways. It could offer hope to Californians suffering from these diseases. It could help relieve the pain and suffering for affected individuals and their families and loved ones. Finally, the economic impact of hESC-based therapies is likely to be significant. Chronic diseases will no longer incapacitate patients and they can return to productive work lives. State government and private expenditures on health care will actually decrease. Companies will organize to commercialize these hESC-based therapies and this will stimulate the California economy by providing new jobs and tax revenue. Most medical economists believe that significant revenues from patents, royalties, and licenses will flow from scientific discoveries pioneered in California based stem cell research centers.
This project will also enhance California's competitive position in biomedical research and push the State to the forefront of research not only in America, but also the world. It will be a reflection of the enormous ongoing investment in science on the part of the state and private institutions, fueled in recent decades by the high-tech and biotechnology industries. All of the research will be done in California. The project focuses on the role of microRNA (miRNA) molecules in controlling the fate of hESCs. miRNAs are recently discovered molecules that play an important part in gene regulation. The expression profiles of miRNAs in stem cells are different from other tissues, and miRNAs may play an essential role in stem cell self-renewal and differentiation. Many potential target genes for miRNAs are essential players in stem cell renewal and differentiation. Some of the most exciting and innovative work on miRNAs has taken place in California and this project will help confirm the State's leading role in miRNA research and California's role as a place where miRNA researchers' specific application to stem cell biology is being studied.


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Mars is the fourth planet from the Sun and the second smallest planet in the Solar System, after Mercury. Named after the Roman god of war, it is often described as the "Red Planet" because the iron oxide prevalent on its surface gives it a reddish appearance. Mars is a terrestrial planet with a thin atmosphere, having surface features reminiscent both of the impact craters of the Moon and the volcanoes, valleys, deserts, and polar ice caps of Earth. Mars is the site of Olympus Mons, the second highest known mountain within the Solar System (the tallest on a planet), and of Valles Marineris, one of the largest canyons.
This article is licensed under the Creative Commons BY-SA License. It uses material from Wikipedia content.

subset: commoncrawl


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The details of Kagen's insults, set forth below, boggle the mind. What kind of person would do something like this? The kind of person that CNN would hire to be a consultant. A quick Googling uncovered the fact that, as per the Democratic Congressional Committee's official web page, Kagen, a doctor, "for seven years was the Allergy Consultant for CNN."
Here is Novak's description of Kagen's vulgar and unseemly actions.
"Newly elected Rep. Steven Kagen, a rich allergist who self-financed his campaign in Wisconsin, by his own account taunted President and Mrs. Bush, Vice President Dick Cheney and presidential adviser Karl Rove during a White House function for new members of Congress in December.
"Kagen told a group of activists that after he found himself in the restroom with Rove, he blocked the White House deputy chief of staff's departure by holding the door closed. According to Kagen, he then said: "You're in the White House and you think you're safe. . . . My name's Dr. Multimillionaire and I kicked your ass."
"The new congressman said he said separately to both Bush and Cheney: "Thank you for coming to Green Bay. I couldn't have won without you coming." Kagen also said he approached Laura Bush and purposely called her Barbara, the name of the president's mother. Kagen's remarks were reported in "The Scene," published in Appleton, Wis."
As per this article in The Scene Online, here's Kagen explaining the how and why of his insult to the First Lady:
Contact Mark at firstname.lastname@example.com
"Then I go to his wife, 'Hi Barbara, how are ya?' I did that because I learned on the campaign that the meanest thing you can say to another gentlemen is, 'he's a fine fellow,' and you then refer to his spouse by a different name.'"


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Siena have been docked another two points in the Serie B table due to financial irregularities for a total of five points.
The Tuscan side was relegated from Serie A in May and narrowly avoided bankruptcy by a matter of hours over the summer.
As the club was in such dire financial straits, it was late in paying certain wages and taxes, which are considered financial irregularities.
Siena had already been docked three points this season for similar issues, but the Disciplinary Commission today ruled they would have another two removed from their tally.
This takes Siena down to just seven points, dropping down to joint 13th place. Click here for the Serie B table.
Follow Football Italia on Facebook and Twitter for the latest Italian football chat


text: hy guys i have tutorial about HDPI device, and i implemented it to MDPI device, success but the button when i hit no action, are this because im using HDPI density pixel on xml ? so the button hit area hiding ? like in HDPI using 48.0 dip and my MDPI device use the same value ? please help me


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Eilean Donan Castle at Night by WaylandscapeWatch
©2011-2016 Waylandscape
Eilean Donan Castle from the same location a little later.
Nice one!
This is unbelievable
Spectacular. I'm afraid words are too cliche to convey scenes like this.
very nice
beautiful place
excellent work
excellent work
national geographic material
Beautiful work! Very Vibrant!
I love opening DA on the newest deviations page to see what stands out and let me tell you this is the only piece that immediately caught my eye! It's beautiful! Well done!


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Better D: South Carolina or LSU?
In a rare matchup of dominant front fours, which team has defensive edge?
Remember those great heavyweight prizefights between Muhammad Ali and Joe Frazier, and Ali and George Foreman? We can't seem to find heavyweight fights like that anymore. They've become extinct.
You know what else is almost extinct? The great front four defensive lines. Deacon Jones and Merlin Olsen of the Fearsome Foursome. Mean Joe Greene and LC Greenwood of the Steel Curtain. They were big, bad guys who got after the quarterback. There aren't enough of those dominant big guys out there anymore, which is one reason why so many teams use the 3-4.
But when the South Carolina Gamecocks meet the LSU Tigers on Saturday night, college football fans will witness something nearly as rare as Halley's Comet: two great front fours on the same field at the same time.
The story of the college football season so far (as it often is in the first half of seasons) has been the huge offensive numbers being put up around the country. But championship-caliber defense, not offense, will become more and more important as we enter the season's stretch run, which is why both South Carolina and LSU remain in the SEC and national title conversation (although LSU will have to win this week to keep its championship hopes alive).
What is it that makes these two units so good? And which one do I think has the edge this weekend and going forward? Let's take a look.
To read the full story comparing the LSU and South Carolina defenses, you must be an ESPN Insider.
Become an insider and get access to all our articles and tools.View Insider Benefits »
Magazine subscribers: activate your Insider account.


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Alzheimer's Prevention as Elusive as Disease Itself
Virginia Stone is worried: Alzheimer's disease seems to run in her family. Her 80-year-old mother, Kazue Storey, was diagnosed seven years ago, and Story's mother died of the disease in the 1970s.
So Stone, 53, watches her diet, and she works out several times a week. She's cut out almost all caffeine; she works puzzles like Sudoku and crosswords.
Her approach sounds like common sense. In fact, many Alzheimer's specialists tell their patients that what is good for the heart -- a healthy weight, daily exercise, no smoking, lots of fruits and vegetables, a network of social connections -- is also good for the brain.
But will a healthy lifestyle help prevent Alzheimer's disease, or at least delay its onset?
As the number of Alzheimer's cases in the U.S. continues to climb, such questions have taken on an urgent feel. The Alzheimer's diagnosis is now shared by 5.4 million Americans, and that number is expected to rise to 16 million by midcentury.
The Alzheimer's Association calls the illness "the defining disease of baby boomers." For them, it's crucial to know whether lifestyle changes will make a difference. But the answer, like so much related to Alzheimer's, is hard to pin down definitively.
Strictly speaking, experts say, the only known risk factor for Alzheimer's is old age. Marked by the death of brain tissue and the resulting erosion of memory and ability to function, the disease is the nation's sixth-leading cause of death and thought to be responsible for 80 percent of dementia cases.
There is no cure, although one medication, Aricept, has been found to delay symptoms in some patients for a year or two.
Unfortunately, research on Alzheimer's -- unlike research on other major killers, such as cancer and heart disease -- remains in its infancy.
Today, scientists know that Alzheimer's begins killing brain cells 10 years or longer before forgetfulness, confusion and other early symptoms appear. By the time memory problems start, the disease is already consuming the brain.
Prevention, or simply finding ways to keep symptoms at bay for another decade into old age, would be a major breakthrough for older adults.
A new UC San Francisco study -- using a sophisticated mathematical model to analyze many years' worth of observational data about the influence of lifestyle on Alzheimer's -- suggests that about half the world's known cases of the disease could be attributable to seven modifiable risk factors. …


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A limited edition 13x16 frame with triple matting under glass features a numbered custom photo of your favorite NBA player as well as a 39mm minted and flashed in gold commemorative team coin and NBA logo coin . An individually numbered certificate of authenticity is matted between both coins. Limited edition of 1000, officially licensed by NBA and proudly made in the U.S.A. by The Highland Mint.
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Steve Houanard suspended
Updated: October 9, 2012, 1:53 PM ETAssociated Press
AIGLE, Switzerland -- The International Cycling Union has provisionally suspended French rider Steve Houanard after he tested positive for EPO.
The UCI says Houanard tested positive for the banned blood-boosting hormone in an out-of-competition urine sample he gave on Sept. 21.
The governing body says Houanard is suspended until the French Cycling Federation completes its disciplinary case.
The Ag2r-La Mondiale rider has the right to attend the analysis of his backup sample.
Read full story
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Crystal Fluttershy WP 1 by AliceHumanSacrifice0Watch
©2012-2016 AliceHumanSacrifice0
very nice
^0^ So pretty!
This wallpaper is very beautifully put together.
This wallpaper is very beautifully put together.
I think this is actually kinda gorgeous ^^
Cwystal Fluttewshy
Such a lovely mane! awwwwww
We need one for Cadence-
aww better than the second one by 100%
wanted to use that cutie mark since forever, the guy is being really nice and making a Pinkie and Twi one for me
Very sweet!


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The Cardinals are closing in on a deal with another of their 2015 draft picks.
It's the final day of Organized Team Activities for the Rams. They are back on the practice field one final time today before breaking until the start of training camp late next... more
Kennys Vargas drilled a two-out, solo homer in the ninth inning to give the Twins at 2-1 win over the Cardinals at Target Field.
The Cardinals and Twins play one more time today. It's the last of four straight Interleague matchups, with the first two at Busch Stadium earlier this week.... more
Tommy Milone tossed seven innings of one-run ball to lead the Twins past the Cardinals, 3-1, at Target Field.
Cardinals ace Adam Wainwright isn't ruling out a return to the field this season. He tells the "Post-Dispatch" he doesn't know if it will happen, but that it is... more
The Cardinals are responding to a FBI investigation into alleged hacking of the Houston Astros database.
The Rams are talking contract extension with new quarterback Nick Foles. Head coach Jeff Fisher says the two sides have had some dialogue about a new deal.
The Washington Senior Legion Baseball Tournament is cancelled. The event was scheduled to get underway today, but the fields are unplayable and rain is in the forecast through the weekend.
The FBI is investigating the Cardinals for allegedly hacking into the database of the Houston Astros.
The KLPW Radio Athlete of the Week is Sophomore Golfer Joshua Jones from Union High School.


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7228 Views 1 Reply Latest reply: Dec 13, 2011 6:50 AM by Demo
Demo Dec 13, 2011 6:50 AM
in response to ecase68
Did you try downloading the updates in iTunes on your computer and them sync them to the iPad? You may just have an available download in iTunes that is preventing the apps from downloading on the iPad. You could launch iTunes on your computer and go to Store>Check for Available Downloads.
Sometimes - signing out of the account on the iPad, restarting the iPad and then signing back in to your account will restart the "waiting" updates. Settings>Store>Apple ID - sign out, restart the iPad and then sign in again. Settings>Store>Sign in.


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I have not been concerned with my cat being around my baby but when people ask if I have a cat they say ohhh be careful. Cats want to curl up with the baby and can smother them. So now, I'm starting to worry. My cat is pretty independent and doesn't really care to cuddle. When my sister in law's baby comes over, she is not interested in the baby because she is moving and being loud and my cat just kind of walks away but I have noticed she likes the carseat and will attempt to get in it. She does not shed so I'm not worried about the hair. I just don't want her to get comfortable around the baby and be too close. Anyone, who has a cat concerned about this for being a first time mommy or anyone with advice who has been through this. A little help would be great!
Anyone worried about having cats?
I have 4 indoor cats. That has never been a problem with either of my kids. Cats don't like loud, unpredictable things....which is a baby. The most they are is curious...and will sniff the baby, but they prefer to keep their distance.
dh (8/99), ds (12/99), 4 miscarriages, LO (5/10), & newb (4/13), 5th m/c (10/14)
I've been worried about the same thing. My cat stays in my room because she doesn't like our newer dog. My cat does like to cuddle though so I'm worried if I let them baby sleep in his bassinet in our room that she might get in there with him.
::Expecting our first baby, Jackson James due April 6th. So Blessed::
I plan to keep the cats out of our room while the baby's sleeping in the bassinet in there with us, and to generally not leave the cats and baby alone and unattended. But otherwise I'm not concerned, and once the baby is big enough to roll over I'll be less concerned about the possibility of them accidentally smothering her.
Here's a picture of Max, almost 3 years ago. This is as close as he got. We have multiple pictures of him getting closer & closer to him...very cautiously. Then that was that...lol :) He wasn't taking any chances that the baby might jump out of the bed at him...
dh (8/99), ds (12/99), 4 miscarriages, LO (5/10), & newb (4/13), 5th m/c (10/14)
i had a cat with my first son, and she would sleep in the crib with him but on the opposite end of the crib... she was such a momma... it was like she was keeping a eye on him or something... i never worried about her smothering him or anything...
Mommy to 3.. William (4/30/02) Dylan (4/26/07) Landon (4/25/13) StepMom to Kaulinand 1 Angel Baby in heaven (2/12) Baby #5 is on the way (due Nov.)
I had a cat but I found her a new home. The baby was only one of the reasons I did this. She was really strange and acted out in ways that made me not trust her to be around my newborn. She's actually a lot happier in her new home. I check in with the new family now and then.
If she had a different personality I might have kept her...but she was just strange and drove me crazy for the four years I had her.
Good luck.
DS Rylan EDD 2/14/99, Born 01/31/99
DD Lyla, EDD 4/02/13, Born 03/18/13
::Expecting our first baby, Jackson James due April 6th. So Blessed::
Learn more
Look how far your child has come.
Review your child's growth milestones.
Read about 35 months : Week 4.
Your growing child
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Your 3-year-old: Learning colors
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Get a glimpse of what's to come.
Read about 3 years 1 month : Week 1.


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Contact Us at (310) 412-1828 or firstname.lastname@example.com
21st Anniversary Breakfast Gala
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Thank you to all who supported our:
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Welcome to our Learning Center where you can access all our content and resources.
Combating obesity (a growing problem for African Americans) helps to fight heart disease and stroke. That is the word from the American Heart Association (AHA), which offers free programs to help fight obesity and other heart disease and stroke risk factors. The programs, which the AHA hopes more blacks will start using, reach people in their homes churches and workplace. While obesity has reached epidemic proportions for all ethnic groups in America, rates are particularly high among blacks: 77.3 percent of non-Hispanic black females are overweight and 28.1 percent are obese.
Obesity is a risk factor for cardiovascular disease.America.s no 1 killer. It occurs when, over time, more calories are taken in by eating than are used up through physical activity. Obesity can end up being the one factor that increases rates of heart disease and stroke in the African American community,. said Augustus Grant, M.D., Ph.D., president of the AHA and professor of medicine at Duke University. .It must be controlled and managed. The one good thing about obesity is that it is preventable, but you have to know how to change your lifestyle. That.s why it is so important for the American Heart Association to provide programs and resources to help people manage their weight and live healthier lives for themselves and their families..
Check Symptoms that apply:
Debbie Allen
Xylina Bean, MD
Holly Mitchell
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Me NOT! :( I love being home with my kids during the summer and all that fun things we did together. I start this Monday... two weeks of training, workshop, prep time etc..
I teach middle school and its my 7th year.
Me NOT! :( I love being home with my kids during the summer and all that fun things we did together. I start this Monday... two weeks of training, workshop, prep time etc..
I teach middle school and its my 7th year.
We start tomorrow with kids. This is my 6th year. I'm ready, but nervous about taking maternity leave the end of Oct. I'm way type-A and have had nightmares about coming back to a chaotic class that hasn't learned anything. DD was born the end of April and I only missed the last 2 weeks of school.
Also, DD is starting preschool (at the school where I teach) and she's been less than thrilled about it. I keep worrying she's just going to cry the whole time (like she did when she and DH visited the end of last year). She just keeps telling me she doesn't like her teacher. She's only met her a couple times. I just tell her she can still have fun, etc. and maybe she'll like her teacher after a while.
I go in next week to set up my classroom but officially start the day after Labor Day. I absolutely am NOT ready to start the year!!! Don't get my wrong... I love my job. I love working with the kids and seeing progress. BUT, I HATE, HATE, HATE having to leave my LO! I really wish I could win the lotto so I could stay home with LO! (Btw, it's my 8th year of teaching).
Proud momma to Jasmin Kristina born 3/3/11
(And a 17 year old... Anaya Dasia)
I started Wed. We survived those first three days of craziness and hoping things settle this week.
Started yr 8 with my 7th graders. Did NOT want to go back thsi year. My babies are so fun (4 and almost 3) ODS starts preK and I won't be able to do ANYTHING with him, not even drop him off/pick him up EVER because he's in the afternoon group. 11:30-2:30. Yeah, cuz that works with my 8:30-3:30 schedule :P
Becky Mama to Joey (5/14/08) and Tommy (10/13/09)
I miss the days when we started after labor day. I went back this last week and the kids start tomorrow. On the plus side, at the end of May we're done.
I'm ready for it. I think I spent more time picking out my outfit than DD did
Mom to two beautiful daughters
YYYSeptember 2001 & July 2008 YYY
Oh man, tomorrow will be the beginning of the 3RD week WITH kids. We went back for "training" on July 30th and kids started August 6th. Early start is all I've ever known since I was a kid even. I wish I lived/worked some place where school started back after the county fair.
Matthew Carson
January 23, 2010
Prudence {P.J.} (30) married to Logan (33)
Lycaeus Anthony 12/22/2010
Prudence Fiona {Fiona} - 6/30/2012
Me (31) + DH (34) = 03/25/03
O born 10/02/11 (.)(.) 23 mo mmc Pascale ^i^ 9/8/13 lost my rose colored glasses Rainbow E born 8/8/14 (.)(.)
Uh, I quickly looked today to see if I brought anything home with me in the spring to help make a few plans....nope. I don't have students until the day after labor day and don't have any paid time at school until the Thursday prior. One day is for our own class prep time and the other day is full of meetings. Fortunately, this will be my 12th year in the same school and I'm teaching grades I've taught before so the first week will be easy enough to get ready over my long weekend in between. It is still summer time with my kids for at least a week and a half anyway :)
Mommy to boy/girl twins born Jan 08!!


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Breast Cancer Health Center
Breast Cancer's Relationship Toll
For many women, the diagnosis of breast cancer represents not only a major physical battle, but also the ultimate emotional challenge -- one that affects every relationship in our life.
Indeed, from friendships to romance, from being a parent to being a daughter, the way you relate to everyone -- and the way they relate to you -- can be affected.
Recommended Related to Breast Cancer
Me and the Girls: Tammy Joyner
WebMD senior writer Miranda Hitti interviewed breast cancer survivors as part of a series for Breast Cancer Awareness Month. The series, called "Me & the Girls," explores the personal stories of these women after they were diagnosed with breast cancer. Breast cancer survivor Tammy Joyner, 49, lives in the Atlanta area. When Joyner was 45 years old, she went to see her gynecologist after noticing some breast changes -- aches and soreness that she wasn't used to. "I said, 'Something's...
Read the Me and the Girls: Tammy Joyner article > >
"I do think cancer has more impact on emotions and emotional relationships than other catastrophic diseases, because with cancer, death is often the first thing people flash on. There's an immediate shock and emotional impact that few other illnesses have," says Katherine Puckett, LCSW, national director of Mind-Body Medicine at the Cancer Treatment Centers of America in Chicago.
Moreover, Puckett says that the uncertainty of the disease itself enhances that impact. "It's the not knowing aspect of breast cancer that increases the emotionality in regard to all your relationships. It heightens anxiety, but it heightens and changes everything in your life," says Puckett.
But the changes, she says, don't have to be negative.
Indeed, for some women, breast cancer can be the catalyst that turns casual friendships into deep and meaningful bonds, that brings couples closer, that helps the family unit become stronger and more cohesive.
For others, however, it can be a lonely and isolating time -- a period of life when people we counted on most seem to all but disappear.
So what is it that determines how breast cancer will affect you and the people in your life? Experts say it's often linked to a willingness to let others share your burden, something that doesn't come easy for many women.
"Women are the caregivers. We are used to taking care of everyone else, so it can be a huge emotional struggle to give up some of that control and let people in. Even with illness, women still want to handle everything on their own," says Gloria Nelson, LSCW, senior oncology social worker at the Montefiore/Einstein Cancer Center in New York City.
Moreover, experts say, many women view asking for help as a sign of weakness, so they won't allow even those who want to help to do so.


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Built in 2008, contemporary style is in heart of close-in Casa Alegre. 3 miles from Plaza, home features luxury upgrades: travertine floors, radiant heat (even in garage!), massage shower in master, & oversized, two-car garage with lots of storage. Green features: insulated casement windows & hot-water circulation pump. Close proximity to parks, shopping, & new trail to downtown.
# of Rooms: 8
# of Bedrooms: 2
# of Full Bathrooms: 2
Fireplace(s): 1
Tile Flooring
Air Conditioning
Hi-Speed Internet Ready
Security System
Single Family Home
Garage Bays: 2
Deck / Patio
Pueblo Revival Style
Single Level (No Stairs)


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American Airlines Posts Adjusted First- Quarter Profit
TheStreet) -- American Airlines (AAMRQ.PK) reported a first-quarter profit, excluding items, for the first time in six years. The carrier, which is operating under bankruptcy court protection, reported net profit of $8 million excluding $349 million in reorganization costs and special items. In the same period a year earlier, the carrier lost $248 million. Including items, American reported a net loss of $341 million, compared with a loss of $1.7 billion. Revenue rose 1% to $6.1 billion, on 1.3% less capacity.During the quarter, consolidated passenger revenue per available seat mile grew 2.6%. Domestic PRASM rose 2.7%, with particular strength in Los Angeles and Chicago. International PRASM grew 2.6%, driven by strong performance in the Atlantic. In Latin America, PRASM was "robust" and the company said "targeted growth in the region will be accretive to earnings." "For the first time in six years, we produced a first-quarter profit, excluding reorganization items and special charges, and our fourth consecutive quarterly operating profit," said CEO Tom Horton, in a prepared statement. "The momentum is building," said Horton, who noted, "Our pending merger with our partners at US Airways (LCC) positions American to be the world's leading airline." American was the first airline to report first-quarter results. Delta (DAL - Get Report) and US Airways are also expected to report first-quarter profits. American said it has completed the majority of its financial restructuring, including reducing debt, renegotiating aircraft leases and facilities agreements, grounding older aircraft, rationalizing the regional fleet, renegotiating supplier relationships. It has also negotiated new labor contracts and reduced depreciation and amortization expenses, which have been offset by the costs related to taking delivery of 36 new leased aircraft during the past 12 months. It will take delivery of 59 aircraft during 2013. On the cost side, consolidated cost per available seat mile decreased 3.2% excluding fuel and special items. Follow @tedreednc -- Written by Ted Reed in Charlotte, N.C. >To contact the writer of this article, click here: Ted ReedDALLAS (
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Hummingbird cake would have to be one of my all time favourite cakes. I love that it's satisfying in it's sweetness, but not overly sickly as chocolate can often be. With the fruit it almost seems a healthy indulgence.
Hummingbird Cake
1 3/4 cups (265g) self-raising flour
1 cup (200g) brown sugar
1/2 cup (45g) desiccated coconut
1/2 cup (55g) coarsely chopped walnuts
1 tsp bicarbonate of soda
1 tsp ground cinnamon
440g can crushed pineapple, drained
2 large over-ripe bananas, mashed
2 eggs, lightly whisked
3/4 cup (185ml) sunflower or vegetable oil
1. Preheat oven to 160°C.
2. Grease a large cake tin.
3. Combine the flour, sugar, coconut, walnuts, bicarb soda, and cinnamon in a large bowl.
4. Mash the banana in a separate bowl and add to the mixture along with the pineapple, eggs and oil. Stir the mixture until combined.
5. Pour the mixture into the greased cake tin and bake for 30 minutes or until a skewer inserted in the centres comes out clean.
6. Set aside on tray to cool completely before icing.
Lemon icing
1 cup (150g) sifted pure icing sugar
1 tsp finely grated lemon rind
1-1 1/2 tbs lemon juice
1. To make the icing, combine the icing sugar, rind and juice, and stir until the mixture is smooth.
2. Pour on to cake and spread with a spatula. Top with some julienned lemon rind to decorate.


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It's Not Enron, It's Facebook
disclosed in SEC documents that of its 900 million users reported in the first quarter, 5% to 6% of them were also false or duplicates, or 55 million to 60 million. As much as I appreciate the company's openness about this issue, I continue to wonder why it insists on reporting figures that include what it knows to be somewhat misrepresented. In this case, it just reported 955 million active monthly users when according to its own investigation the real number is possibly 100 million fewer.The answer is simple. Its business model relies on targeted advertising. The higher the number the more it can charge. As Enron changed the world of auditing and corporate ethics, it seems Facebook will have a similar impact in the way investors view future initial public offerings. What's more, the company has created a much-needed pessimism toward anything that is built up as "larger than life." Facebook's continued stock decline will likely change the way future IPOs are viewed and scrutinized and become public issues in the same way Enron brought corporate change with Sarbanes-Oxley. But that's where the similarities end. Facebook is not Enron. Where it was clear with Enron that criminal acts had taken place, Facebook's only crime in this situation is that it has failed to live up to investors' expectations. Follow @rsaintvilus At the time of publication, the author held no position in any of the stocks mentioned. This article is commentary by an independent contributor, separate from TheStreet's regular news coverage. Richard Saintvilus is a private investor with an information technology and engineering background and has been investing and trading for over 15 years. He employs conservative strategies in assessing equities and appraising value while minimizing downside risk. His decisions are based in part on management, growth prospects, return on equity and price-to-earnings as well as macroeconomic factors. He is an investor who seeks opportunities whether on the long or short side and believes in changing positions as information changes.However, this is not the first time this issue has come up. Prior to going public, the company
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Plus Blog
May 31, 2010
We've all struggled with knots. As anyone who owns an MP3 player or mobile phone knows, anything but the most careful winding of the headphone cord or power cable can result in a hopeless mess of tangles.
Knots are more than simple irritations, they can actually pose a threat to life. A single knot can reduce the breaking strength of climbing rope by up to 50%. Spontaneous knot formation in umbilical cords can quadruple the risk of fetal mortality. Spontaneous knotting in DNA leads to faulty gene transcription and an increase in the rate of potentially dangerous mutations.
Despite this, remarkably little is known about the formation of knots — or how to prevent them. This is why the University of Aston is proposing a mass experiment to fill in some of the gaps in the science of knots and address a mathematical conjecture. Researchers are looking for groups of keen students in schools who want to involve themselves in active data gathering and interpretation and to contribute to a genuine piece of novel science.
Your school's involvement and effort need not be extensive. The experiment can be carried out in school, in a class environment, with minimal resources (several lengths of string), and typically involving an hour or so per week for two or three weeks. It could form part of a national curriculum case study in Key Stage 3 or 4 to use mathematics to solve problems, or as an open ended mathematical investigation.
The results of this major experiment will be announced at an open public talk at the forthcoming British Science Festival hosted at Aston University in September 2010. If you are interested, please register by contacting the Knot Experiment Coordinator, Vicky Bond by email (email@example.com) or post (The Knot Experiment, Aston University, Aston Triangle, Birmingham B4 7ET).
May 23, 2010
Some of Gardner's books, and books inspired by him, have been reviewed on Plus:
May 3, 2010
Two A-level students could win the trip of a lifetime, joining NASA to look for life at the edge of space.
As part of their education programme, NESTA is offering two A-level students the opportunity to take part in a research trip to NASA and the Black Rock Desert in Nevada, USA. They will be joining three NESTA scientists who been working to discover what kinds of life exist at the extreme edge of the atmosphere. Together with a NASA astrobiology team, they will launch a robot 40 kilometres into the stratosphere on a powerful rocket.
Details of the competition challenge and how to enter can be found on the NESTA website. But note that the deadline is tight, due to the amount of time it takes to get security clearance to enter the NASA base the entries need to be back by 24 May 2010. But take this as a good sign — a tight deadline may mean fewer applications and you might have a greater chance of success than you think!
So good luck, and see you in the stratosphere!
April 27, 2010
Did aliens help prehistoric Britons found the ancient Woolworths civilisation? And what does tying your shoe laces have to do with DNA? Find out with this year's popular lectures organised by the London Mathematical Society. Matt Parker of Queen Mary, University of London, will explore how seemingly incredible results can actually be meaningless random patterns, and Dorothy Buck of Imperial College, London, will look at how mathematical knot theory helps to understand DNA.
When and where: 7pm, 30th of June 2010 in London and 6.30pm, 29th of September 2010 in Birmingham
Tickets are free but please book a ticket by the 25th of June and 24th of September respectively from Lee-Anne Parker, London Mathematical Society, De Morgan House, 57-58 Russell Square, London, WC1B 4HS (email: firstname.lastname@example.com).
April 27, 2010
Due to popular demand, we're revisiting our poll to find your favourite fictional mathematician.
It is quite difficult to compile a list of fictional mathematicians. Scientists are often portrayed in films — usually as mad — but there are very few who are specialised mathematicians. Here at Plus, we have come up with a list that we think covers most well-known fictional mathematicians, although it is debatable whether some are even mathematicians at all! We are asking for your opinion — who is your favourite?
Have we missed yours off the list? Please leave a comment and let us know. We will write a biography of the character who wins the poll.
7 comments
March 24, 2010
Wednesday, March 24, 2010
The Abel Prize 2010 has been awarded to John T. Tate from the University of Texas at Austin "for his vast and lasting impact on the theory of numbers". The honour puts Tate on a par with a Nobel Prize winner. In fact, the Abel Prize was established to make up for the fact that there is no Nobel Prize in mathematics.


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Sprint Nextel Corp has recently unveiled its plans of introducing 4G LTE network, which would boost the mobile broadband network services. It has further been informed that initially 100 million Americans would be allowed to experience the new 4G LTE network.
The 4G LTE network plan would be introduced in six cities. 4G LTE network would be available to the iPhone users. There are a few who are of the view that the Sprint's plans of introducing 4G LTE network might not work as its rivals are also gearing up to launch faster broadband services. The Chief Financial Officer of Sprint, Joe Euteneuer said that the company is playing safe by introducing the network to only six cities till midyear.
In the last quarter, iPhone had helped Sprinter in keeping 1.8 million customers and at the same time, it also booked significant revenue. Apple has recently rolled out its 4G LTE-capable iPad tablet computer. Sprint would no doubt be benefited by the launch of the tablet as it requires 4G LTE network.
It is hoped that Sprint Nextel Corp would be able to achieve its goals through the introduction of the 4G LTE network. The shares of Sprint are performing poorly at the moment as they have shed 5 cents.


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Current Residence: not saying...
deviantWEAR sizing preference: ???
Print preference: ???
Favourite genre of music: I can't really specify...
Favourite photographer: none
Favourite style of art: Anthro, preferably...
Operating System: ???
MP3 player of choice: iPod nano
Shell of choice: ???
Wallpaper of choice: I don't got one. Options anyone?
Skin of choice: scaly dragon skin and shark skin
Favourite cartoon character: my own.
Personal Quote: never be afraid to unleash your true self...


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Check out these bargain stocks
Downsizing may be appealing, but consider these first
Join the NASDAQ Community today and get free, instant access to portfolios, stock ratings, real-time alerts, and more!
Chromebook manufacturers are gearing up for their next round
of upgrades. According to
, Acer will release a new 11.6-inch model in July. The new
machine is expected to follow in the footsteps of its
, the C7, and will be geared toward students.
Acer's new Chromebook is set to ship at a time when the firm's
sales have plummeted. Last year, Acer reportedly shipped anywhere
from 150,000 to 200,000 Chromebooks per month. DigiTimes' sources
claimed that shipments plunged in January, with estimates falling
between 20,000 and 30,000 units. This prompted Acer to take
action and release another upgrade.
These shipment figures seem to contradict a previous DigiTimes
report, which claimed that the Chromebook's
lifetime sales
had yet to reach 500,000 units.
To be clear, there is a significant difference between the
number of units that are shipped and the number of units that are
sold. However, if Acer had enough orders to ship 150,000 units
per month before Christmas, one would imagine that the lifetime
sales were higher than previously estimated.
Acer is not the only company set to ship new Chromebooks in
the latter half of the year. Asus, which previously had no plans
to build a notebook for Google (NASDAQ:
), will reportedly release its first Chromebook in 2013.
Lenovo and Hewlett-Packard (NYSE:
) are also expected to release new Chromebooks this year, along
with upgrades from Samsung.
At the same time, Google is reportedly "cooperating" with
Samsung, Asus, Hewlett-Packard and Acer for a series of new
DigiTimes' sources believe that by releasing two entirely
different kinds of laptops, Google -- together with its many
partners -- will force Microsoft (NASDAQ:
) to "take a more cautious approach when making strategies for
licensing fees or entering the hardware business."
While Microsoft had historically produced operating systems
and other software exclusively for its vendors, the company
decided to get into tablet manufacturing last fall when it
released the first Surface.
The second Surface is expected to be released this summer, but
that may not be all that the Windows maker has planned.
Next month Microsoft will unveil its third-generation Xbox.
The console, which is tentatively being referred to as Xbox 720
by the gaming press, is rumored to be released alongside an
Xbox-themed tablet. Microsoft is expected to use the unconfirmed
device to bolster the Xbox brand while strengthening its position
against Sony (NYSE:
) and Nintendo (OTC:
), both of which already produce handheld gaming devices.
Louis Bedigian is the Senior Tech Analyst and Features Writer
of Benzinga. You can reach him at 248-636-1322 or
louis(at)benzingapro(dot)com. Follow him
(c) 2013 Benzinga.com. Benzinga does not provide investment
advice. All rights reserved.
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. Gain access to a streaming platform with all the information
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The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.
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Call (800) 262-8464 Monday-Friday, 8am - 9pm ET Sat, 9am - 6pm ET Sunday, 9am - 6pm ET
The Lugz 2 is similar to the Bubba series from WOW but with an added dimension. The new curved aerodynamic shape gives the riders the option of steering this 2 person towable tube. This boating tube comes with 3 tow points. One for front towing, one for back towing, and one on the bottom for optional steering capability. You can sit, kneel, stand or lay down on this tube. By shifting your weight from left to right you can take control of where you want to go or you can just back and ride it like a regular towable tube for boating. The U-shaped body design slips over the boat wake easily for a fast-action, thrilling ride not found on most other inflatable towables.
|Curved U Shape
|6'2" Length x 5'6" Width
|PVC Bladder Nylon Cover


text:
Researchers at ETH Zurich have developed a modulator that is a 100 times smaller than conventional modulators, so it can now be integrated into electronic circuits. Transmitting large amounts of data via the Internet requires high-performance electro-optic modulators — devices that convert electrical signals (used in computers and cell phones) into light signals (used in fiber-optic cables).
Today, huge amounts of data are sent incredibly fast through… read more


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Hello! This is my first post on here, but I've been reading for the last couple of months. There is some amazing talent on this board, so I'm hoping someone can give me some suggestions.
We live in an old house (built in 1901) and I am having the hardest time with the windows. In our dining room, we have 3 windows right next to each other. The one in the middle is large and the two on the outside are really thing. There is stained glass above the middle one. Would you just use two panels, similar to what you would do with a single large window? Also, in the living room, there is a bay window. Once again, the windows are all right next to each other, and there is a radiator in the center. The middle window has a leaded glass in the top part of it. Any suggestions for this?
I have a TON of other questions about decorating, but I'll start with just one. Thanks. :)


text:
Works as described and is extremely quiet. Highly recommended.
Great Watch winder. fantastic price from overstock. Winder comes with everything that would have been included if purchased from a high end watch dealer. Wolf packaging and dust bag. Great Purchase
I've had the winder for about a month now and I'm very happy with it! The motor is very quiet and not a problem if its in your bedroom while you sleep. I do wish it was real leather, but that's no fault of Overstock. I especially like the storage space on top for my keys and a money clip.
- How did the image on site compare with the actual product? Exact
- How accurate was the sizing? I didn't check the dimensions before buying


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'The Strangers' Director Bryan Bertino Will Force People to Do His Bidding for 'Mockingbird'
- By Scott Beggs
- @scottmbeggs
- January 31, 2012
Bryan Bertino crafted a fantastic home invasion flick with The Strangers. It was environmental and terrifying, but it also seemed fresh while playing off of old standbys in the genre. Now, he'll be joining the handful of directors attempting to breathe life into Found Fauxtage. According to Shock Till You...
Short Film of the Day: Mockingbird
- By Scott Beggs
- @scottmbeggs
- April 16, 2011
Why Watch? Because sometimes it only takes a minute to be scared to death. A father sits at his computer listening to the soothing sounds of his young child on a baby monitor. In the tightest storytelling possible, it goes from sweet to shattering in a short that has to...


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Role-Playing Scenarios
Only a few of the following examples are actually ready-to-run in an undergraduate classroom, but they will provide inspiration and materials for your own role-playing exercises. Many of the scenarios, characters, and assignments need a few added details, which will enable you to tailor them to your course.Help
Show all pages
Earth System Topicsshowing only Hydrology Show all Earth System Topics
Earth System Topics Show all Earth System Topics
- Ground Water 2 matches
- Surface Water 2 matches
Hydrology5 matches General/Other
Results 1 - 6 of 6 matches
Water Wars: A look at Gallatin Valley Water Controversies part of Cutting Edge:Topics:Public Policy:Activities
This virtual field trip explores the science and policy of a ground water dispute in Gallatin Valley Montana. The virtual field trip uses a role-playing activity to explore the geology, hydrology and policy related ...
Learn more about this review process.
Transnational Pollution: Why Are You Dumping on Me? part of Pedagogy in Action:Library:Role Playing:Examples
The purpose of this lesson is to familiarize students with the different types of transnational pollution, by having them role-play in a hypothetical disaster on the Danube River.
Ideas for Resources: Geology Lab Manual part of Pedagogy in Action:Library:Role Playing:Examples
This site offers an overview of role-playing activities and contains a partially-fleshed-out list of questions and situations dealing with water, minerals, and public policy.
Science in the Courtroom: The Woburn Toxic Trial part of Pedagogy in Action:Library:Role Playing:Examples
In this exercise, hydrology students role-play expert witnesses in a mock trial dealing with contamination of groundwater.
The High Plains: Land of Extremes part of Pedagogy in Action:Library:Role Playing:Examples
This lesson plan includes a debate about whether the black-footed ferret should be reintroduced onto public lands and a study of the High Plains habitat.
The Grand Canyon part of Pedagogy in Action:Library:Role Playing:Examples
This interdisciplinary lesson plan deals with the consequences of damming in the Grand Canyon area. The students, role-playing as scientists, write a proposal to try experimental flooding.


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If your company decides to host i-lign inhouse, you may find the following articles useful. They describe the process for installation by the i-lign team, and for self-installation, as well as the technical requirements.
Instructions for installing the i-lign server stack on a Windows 2012 server.
See Server Requirements
The system requirements for servers are only applicable if you are hosting the i-lign server yourself. Please see our Knowledge Base article on Running i-lign In-house for more details.
For externally hosted deployments, only the client requirements apply.
i-lign is a web-based application and users only require a supported web browser to use most of the features.
These are the browsers we support and recommend for the best experience using i-lign:
This article describes one way you can connect IIS to Tomcat on Windows and delegate Single Sign On authentication to IIS.
This example assumes you already have the following:
Restoring a previously hosted database.
It is possible to integrate i-lign into your authentication infrastructure by delegating the authentication to a native web server or reverse proxy installed on the same server as i-lign.
Our standard approach is for the front end web server or proxy to communicate to the Tomcat application server via the AJP binary protocol. There are AJP modules available for web servers like IIS and Apache.
This approach allows you to pick and configure an integration method that suits your network.
When installing another i-lign instance on an existing i-lign server, the process is the same but you will need to take note of the following points:
The following series of articles provides information about installing a production and test instance of i-lign on Windows, and installing databases.


text:
JudasMyGuide Jun 25, 2011 6:14 PM
in response to Dan Gibbons
Hi I had the same problem. But i managed to fix it.
first i reset my network settings on the iphone and turned it off. Then i unplugged my internet router for 20 seconds and let the router reboot. After it rebooted, i turned on the iphone and looked for my wifi connection and entered my password. Lo an behold, I can now get wifi on my 3g. I think the important thing here is dont just reset your router, you need to unplug it for a bit so it resets the ip
steve1989 Jul 3, 2011 9:23 AM
in response to Dan Gibbons
i see all over these forums that its after 3.0 other saying 2.2 and few more. i think alot of people are trying to blame the firmware after a certain time but its alot of different firmware for this to happen to.
i have been switching from firmware to firmware over the past week from 2/3/4 and it seems that i caused this problem from upgrading firmware but not by any paticular one. obviously i don't claim blame for this. apple has forgotten their responsibilities and someone should make this obvious for future apple customers eg: channel 5 new lol.
but back to the point i personnally dont blame a certain firmware but the process of putting a new one on my iphone. i have done alot of changes plus jailbroken my phone with all kinds of software and tried many workarounds. but so far nothing. basically i think you have to take it to a professional and have them replace the wifi chip or do it yourself.
no point wining about spilt milk now cuz ya <edited by host> mother aint gonna come clean it up (thats apple)
do yourself a favour and sell it for spares/repair and buy yourself a blackberry or htc. atleast microsoft try to fix your shiz for you
Mrsfoot Jul 27, 2011 6:51 AM
in response to Dan Gibbons
Oh well, it looks like I am joining the hundreds of you with this stupid update issue.
Daughter has 3g 8gb. From updating it to os 3.1 ifi no longer works.
Emailed cpw (where it was purchased), was told they know of no issue and that Apply do not know of any issue either. Now, either cpw and Apple cant read or they are lying....you choose!
I have spoken to a number of consumer programmes who may be interested in this. So, if you have been affected by this and you are happy for reporter etc to ask you some questions then please email me at firstname.lastname@example.com with your details.
Apple dont know about the issue??...they will soon!
pianoplayerjohn Aug 15, 2011 12:59 PM
in response to Mrsfoot
Hi Mrsfoot, I was having similar issues by the wifi on my iphone being greyed out. I have 2 iphones both 3g one for my wife and one for myself. I jailbroke and unlocked both of them because neither of us like AT&T and wanted to use T-mobile instead. On one iphone, wifi showed up with the network address but the other one did not. Both have been upgraded to 4.2.1 and 6.15 firmware. After hours of seeking a solution by making sure airplane mode was off and restoring the networks and lots of other things without success, I found that indeed my wifi was working when I clicked on Safari and went to my home page and other sites with no problems. Kinda weird but thankful my wifi works.
I thought I'd share this just in case some of you might be in the same boat and have wifi even though the iphone says you don't.
I hope Apple fixes this problem at some point and I thank you for your efforts. Hope this helps someone...
Goodmandeepinside Aug 21, 2011 3:32 PM
in response to pianoplayerjohn
I was having this issue everyday and had to do a hard reset each day to make it recognize wifi.
Got to thinking it started happening only after afew days of installing Facebook app on the phone!
So I removed that, and believe it or not - NO problem since that day- its been aweek now
Me happy again. :)
neverapplicable Sep 23, 2011 10:51 AM
in response to Goodmandeepinside
I wish that was my case. I've tried basically everything and opted out of using any apps other than the basics to see if miraculously it was an app problem.. but no Why does this have to happen to all of my apple touch products.
jimbob18 Dec 18, 2011 8:36 AM
in response to Dan Gibbons
I have a similar problem...but a different explanation. My iPhone 4 with iOS 5 will drop my wifi connection (with 2 strength bars) and try to switch to 3G. When I am at home I turn off 3G so I will get a notification box saying "Cellular Data Is Off". As soon as I go to "Settings" it miraculously picks up wifi again!!!!!
This is obviously a ploy by the carrier to rack up excess data charges. They don't make money when we use wifi and the fact that it picks back up AT THE EXACT MOMENT THAT I GO TO NETWORK SETTINGS is very, very SUSPICIOUS!
I realize that you dedicated Apple types would NEVER accept collusion between Apple and the carriers but 2 months ago you never would have accepted Carrier IQ either.
Cedricsav Dec 24, 2011 10:24 AM
in response to Dan Gibbons
OK so it appears clear that the problem is not an isolated case, that Apple clearly knows that people can't use their phone to connect to the Internet, and that this rotten company refuses to even admit that there is a problem.
Then it is clear that consumers such as myself, even after buying 3 Mac Book Pros and iphones will buy Samsung next.
Thanks for making your own products unusable and making us spread the word that you'd have to be a fool to buy Apple products...
Rightohh Feb 24, 2012 2:47 AM
in response to Dan Gibbons
I have read most of these posts..
I never post but, THIS WORKED for me..
I put the ipone 3g in the deep fridge (on some plastic) left it in there for 15 minutes.
BOOM WIFI worked a couple of minutes later.. But then stopped..when the phone warmed up..
30 minutes later i placed the the iphone outside in the sun (hot sun) wrapping mostly in a white hanky except for the bottom of it, so covered about 2/3rds of the phone with a hanky leaveing the bottom one third exposed to sun rays..That didnt work..But...
Anyway a couple of days after about 1 year of trying everything, and i mean everything..WIFI works all day every day.. Go figure..
Maybe it was the fridge, or combination of both methods.. In any event i HAVE A WORKING WIFI..


text:
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About Me
No more missions, just loving the rest of the ride ;)
I am a traveller, a crazy italian woman with a hunger for life and experiences. I like my parties, the company of good people and everything that is new to me.
I want to learn as much as I can during my time on this wonderful planet, coming as close as possible to wiseness and universal love. I want to be the 70 years old lady rocking up the dancefloor. I want to keep the good energy going. I want what I have :)
Why I'm on Couchsurfing
Send me a message for some tips, a chat over coffe or if you wanna join me and my friends on a night out in the town!
Been hosted by the awesome Anderson Aldrich in his house, enjoyed a crazy CS party involving dozens of amazingly open people, a fair amount of balut eggs, a rooftop pool and more speedos than I would care for.
Playing music around a campfire, singing gospel and rock, dancing salsa, having meaningful conversations, eating delicious food, cooking, drinking red wine, having a good party, walking in the park, scuba diving, horse riding, socializing.
Music, Movies, and Books
J.M. Auel, The valley of the horses.
Alanis Morrissette, Jagged Little Pill
One Amazing Thing I've Done
Taking tick's off my travelbuddy's bum in the Guatemalan jungle on a 6 days horseback trek.
Seing a marine turtle play with my bubblerings while Scuba diving
Splitting my chin open on the bottom of a canyon in Western Australia
Getting rescued by a total stranger who borrowed me 10 bucks on the Mexican border when I was stuck without my credit card
Teach, Learn, Share
Best thing I've ever learned: I know nothing! :)
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DO Corner
What does Unified GME mean for DO students?0
By Ryan Nguyen
In a statement released in late February 2014, the American Osteopathic Association (AOA) and the American Council on Graduate Medical Education (AGCME) announced they have finally agreed to a single accreditation system for graduate medical education. The surprising news comes on the heels of previously failed negotiations in July 2013.
From the official press release:
"From July 1, 2015 to June 30, 2020, AOA-accredited training programs will transition to ACGME recognition and accreditation. There will continue to be osteopathic-focused training programs under the ACGME accreditation system. Two osteopathic review committees will be developed to evaluate and set standards for the osteopathic aspects of training programs seeking osteopathic recognition. DOs and MDs would have access to all training programs. There will be prerequisite competencies and a recommended program of training for MD graduates who apply for entry into osteopathic-focused programs. AOA and AACOM will become ACGME member organizations, and each will have representation on ACGME's board of directors." (more…)
Start Early and Do Lots of Questions: Acing COMLEX and USMLE Prep3
By Ryan Nguyen
Many osteopathic medical students at the beginning of their second year struggle to come up with a game-plan to prepare for the COMLEX Level 1 and USMLE Step 1. With a disturbing number of resources and study plans to choose from, how can students determine what strategy will maximize their board scores?
Early in my second year, I scoured the depths of the internet pouring over the study schedules and tips of past test takers. I was looking for "the one," a study schedule that would get me the scores of my dreams. The dirty secret to success? There was no one study plan that triumphs above all. While they all varied in their day-to-day plans, study plans from top scorers all echoed the same two principles: start preparation early and do lots and lots of practice questions.
This post is dedicated to when to start preparing and how many practice questions to do. (more…)
Audition Rotation: What are they? How do I do well?2
One of the biggest differences between applying for osteopathic residencies compared to allopathic residencies is doing an audition rotation. I was recently on a rotation where the program director told me they had not ranked anyone who hadn't rotated with them in ten years. Audition rotations allow a program to see if you fit into their system. They also allow you the chance to prove you know your stuff. But they can also sink you in a matter of hours. In the osteopathic world, audition rotations are a must, and the first half of your fourth year is going to be filled with high stress rotations.
This post is dedicated to how to schedule your rotations and how to succeed at them.
Searching for Osteopathic Residencies0
While the process of applying to residency can be very stressful, there are resources available through the American Osteopathic Association (AOA®) that make finding residencies a breeze. Researching residencies can be a fun way to kill time. I have found that it gives me something to work for, giving test taking and studying some semblance of purpose. With a fresh batch of third years in the hospitals, I was surprised to see how many didn't know about various web sites and search engines for AOA-approved residencies. So, this post is just a friendly reminder of what resources are available to make your life a little easier.
DO Corner: Using OMT on Rotations0
With COMLEX now behind you, it is time to start learning some clinical medicine. One area in which many osteopathic students have trouble is using OMM in the hospital. Many students are afraid to ask attendings permission to perform simple techniques. So here are a few tips to help you get the ball rolling.
Do Corner: Tips for Tackling the COMAT shelf exams1
Congratulations to most of you on finishing the COMLEX Level One exam. But, just when you thought you could take a break from standardized testing, the COMAT exams are right around the corner. The COMAT exams are the osteopathic version of the allopathic shelf exams. While every school uses COMAT scores differently, the goal of this post is to give you some tips for studying and rotations in general.
DO Corner: COMLEX Test Day Tips1
COMLEX test day is your chance to prove that you have mastered the first two years of medical school. To those of you who have reached this milestone, congratulations! To the rest of you, read on. The goal of this post is to try to give you a couple of tips to make the big day easier.


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Wolf Paw Print by MissionpbWatch
©2009-2016 Missionpb
I have created a wolf print in various sizes. Please feel free to use! I would love to see what you created with it.
Really spiffy tracks! I've used it as a background accent on my blog, The Wolf's Den. You've been attributed here and soon on a permanent page.


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Special Events
Carlsbad Art in the Village: The Carlsbad Village Association's 16th annual art fair will feature more than 100 local and regional artists showcasing their work, along with live music and other activities. 9 a.m. to 5 p.m. today. State Street and Grand Avenue, Carlsbad. Free. (760) 945-9288.
North San Diego Antiques, Art & Collectibles Show: Local vendors with $5 on-site appraisals (early-bird admission at 8 a.m. is $5). 9 a.m. to 3 p.m. today. St. Mark Golf Club, 1750 San Pablo Drive, Lake San Marcos. (760) 580-1505.
Full Moon Poets Summer Poetry Slam: La Paloma Theatre hosts the semiannual gathering of spoken word artists. 7 p.m. today (aspiring poets should be in line by 6 p.m. Names will be drawn for the 17 contestants at 6:30 p.m., when doors open. 471 S. Coast Highway, Encinitas. Free (but donations taken for winning poet). fullmoonpoets.org.
Dinner and a Movie: Leo Carrillo Ranch Historic Park hosts its annual summer dinner show, featuring a barbecue dinner followed by an outdoor screening of Carrillo's "Honolulu Lu." 6:30 p.m. Friday. 6200 Flying LC Lane, Carlsbad. $40 (includes dinner and door prize raffle ticket, silent auction entry and popcorn). (760) 476-1042.
Concert & Movie: Oceanside presents a concert by the Box Canyon Band followed by a screening of "Rio 2" in Mance Buchanon Park. 5 p.m. to 9:30 p.m. Friday. 425 College Blvd., Oceanside. Free. Refreshments sold on-site. (760) 435-5041.
Summergrass San Diego: The 12th annual bluegrass festival in Vista will feature music by Michael Cleveland & Flamekeeper, Special Consensus, Della Mae, Bluegrass Etc., Front Country, Virtual Strangers, Sweet Tidings Gospel Jam, Sonora Dogs, Molly Tuttle & John Mailander, Prairie Sky, Shirt House Band and Rusty Gait, along with live music jams, children's instrument camps and adult boot camps. Friday through Aug. 17. Antique Gas & Steam Engine Museum, 2040 N. Santa Fe Drive, Vista. (858) 679-4854, summergrass.net.
Great Horror Campout: Bates Nut Farm hosts a stop on this touring 12-hour overnight horror adventure with horror film screenings and interactive live scares from costumed monsters and demons all night long. 8 p.m. Friday to 8 a.m. Saturday. 15954 Woods Valley Road, Valley Center. $99 for four-person tent, $129 for two-person tent. greathorrorcampout.com.
Historic Encinitas Bus Tour: The Encinitas Preservation Association and Sea Coast Exclusive Properties present a four-hour bus tour of 50 historical points of interest with scheduled stops at several landmarks. 9 a.m. to 1 p.m. Aug. 16. Encinitas 101 MainStreet, 818 S. Coast Highway 101, Encinitas. $40 ($5 lunch available). (760) 753-4834.
Professional Bull Riding: The ninth annual Del Mar Invitational, a touring pro division event, includes championship bull riding, bull poker, cowboy teeter-totter and more. 7 p.m. Saturday. Del Mar Arena, 2260 Jimmy Durante Blvd., Del Mar. $26-$66. $10 parking. sandiegopbr.com.
Ricardo Lemvo & Makina Loca: Cuban/Afro-pop/salsa band at TGIF Jazz in the Parks. 6 to 8 p.m. Friday. Calavara Hills Community Park, 2997 Glasgow Drive, Carlsbad. Free (bring own seating). carlsbadca.gov/arts.
Big Band & Jazz Hall of Fame Orchestra: Willowbrook Jazz at the Pond summer concert. 4 p.m. Saturday. Willowbrook, 2732 Hutchison St., Vista. $20. (760) 726-8909.
Flip Oakes Dixieland Jazz Party: Willowbrook Jazz at the Pond summer concert. 4 p.m. Aug. 17. Willowbrook, 2732 Hutchison St., Vista. $20. (760) 726-8909.
San Diego Cajun Playboys: French Cajun band. 7 p.m. Aug. 21. Fallbrook Library, 124 S. Mission Road, Fallbrook. Free. (760) 224-1805.
The Mighty Untouchables: Cover dance mix septet at TGIF Jazz in the Parks. 6-8 p.m. Aug. 22. Calavara Hills Community Park, 2997 Glasgow Drive, Carlsbad. Free (bring own seating). carlsbadca.gov/arts.
Speed of Sound: Jazz quartet. 8 p.m. Aug. 22 and 23. PowPAC, Poway's Community Theatre, 13250 Poway Road, Poway. $22. powpac.org.


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Alkaline phosphatase (ALP) is an enzyme naturally present
throughout your body. It comes in many variations called isoenzymes. Each
isoenzyme of ALP is different, depending on where in your body it's made.
Your bones make an isoenzyme called ALP-2. Levels of this enzyme
increase when bones are growing or bone cells are active.
An ALP bone isoenzyme test can detect abnormal levels of bone
growth that may be associated with conditions such as:
Other names for an ALP bone isoenzyme test include:
Doctors order an ALP-2 test if they're concerned you may have a
bone disease.
The symptoms of bone disease include:
An ALP-2 test can also be used to monitor bone disease
Your doctor may tell you not to eat or drink anything for six to
12 hours before the test. You may be asked to stop certain medications before
the test. Follow your doctor's orders carefully. Your test results could be
incorrect if you don't.
Certain drugs may affect ALP-2 levels. These include:
It's important to tell your doctor about all the medicines
you're taking. This includes both prescription and over-the-counter drugs.
The ALP bone isoenzyme test is a blood test.
A nurse or laboratory technician will draw your blood.
A tourniquet will be tied around your upper arm. A vein will be
located for the blood draw. The area around it will be cleaned. A needle will
be inserted, and blood will be drawn into a small vial. You may feel a slight
pinch. Your blood will be sent to a lab for diagnosis.
Sometimes, blood may be taken from a vein on the back of your
hand instead of from one inside your elbow.
The ALP bone isoenzyme range for healthy adults is 12.1 to 42.7.
Children have higher levels of ALP bone isoenzyme. ALP-2 is also
elevated in people with broken bones. In both groups, bone growth is expected
and normal.
Higher than normal levels of ALP bone isoenzyme could indicate a
bone disease such as:
An elevated test result could also indicate serious conditions
such as hyperparathyroidism or leukemia. Both diseases affect your bones as
well as other parts of your body.
Test results below normal are sometimes found in people with malnutrition
or anemia. Results that are below normal can also be found in women who take
estrogen after menopause. However, high levels are much more common than low
The ALP bone isoenzyme test isn't used to diagnose a disease on
its own. It can only narrow down the list of causes for your symptoms.
If you have a positive test, further tests will probably be
necessary. These tests will determine what type of bone disease you may have.
Change your life with these simple tools


text:
Search Swinburne Research Bank
Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/33230
- Title
- Towards the big turn-off
- Author(s)
- Simons, Margaret
- Abstract
- Almost 30 per cent of Australian households now have digital free to air television, according to research released last week, and it is estimated that over 40 per cent of Australian households can receive digital TV if those who get their service piggy-backed with pay television are included. These are vital statistics for those interested in media diversity. On the face of it, the figures are cause for optimism---but there are still plenty of worms in the apple. [Introduction]
- Publication type
- Commentary
- Source
- Creative Economy Online, 07 June 2007
- Publication year
- 2007
- Keyword(s)
- Australia; Commercial television; Digital television; Federal government; Free-to-air; Media diversity; Packer, James, 1967-; Pay television; Technology
- Publisher
- ARC Centre of Excellence for Creative Industries and Innovation
- Publisher URL
- Copyright
- Copyright © 2007 Margaret Simons.


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Carthage senior Chloe Shepherd looks for a shot in Carthage's 69-58 win over the Lady Panthers of Raymore-Peculiar on the opening night of the Nevada Classic tournament Tuesday. [Order this photo]
Republic sophomore Kori Taylor shoots for two over Joplin's Danielle Hollingshead during opening night action at the Nevada Classic tournament Tuesday night. Republic won the game, 70-21. [Order this photo]


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Holden Zuck Jan 30, 2013 2:22 AM
in response to brian sit
I've got the same problem. I've got a powerpc Mac mini that works fine via DVI-HDMI adapter with hp w2207h display. I bought the new mac mini (late 2012) and the hp display flickers a while and shows me a black screen when connected via HDMI cable.
mevanpl May 1, 2013 8:32 PM
in response to Holden Zuck
You can use HDMI cable with HP w2207h directly,No need for other cable. but please follow these step.
1.Find LCD tv to set up first step.
2.Connect HDMI cable to LCD TV(i use Samsung) and adjust to HDMI source.
3.Open Mac mini.
4.Open system preference.
5.Click "display" you will see that the primary setting is :1680*1050 that HP monitor did not support.
6.Unplug HDMI cable from LCDtv (no need to shut down) and plug into HP w2207h.
7.the screen still blinking, it is ok.
8.On HP monitor, Push down button "Select" and "+" and the same time and hold it.
9.Use mouse or down button on keyboard to choose screen resolution to be "1600*900"
10. Then the screen will not blinking and you can use your lovely HP w2207h
if you want a high resolution on screen.
1.Buy new LED monitor that support 1680*1050 resolution.
2.Buy Mini displayport to DVI for digital signal Mini>DVI>HDMI.
Enjoy your MAC. because i am new Mac user with my MAC mini


text:
Login Vulnerability in KDE 3.3.0 through 3.5.7
The KDE Display Manager (KDM) can be exploited to allow users to log in without a password. This would give users the ability to log in as other users or even root.
The threat affects password-protected accounts in specific conditions; for example if auto-login is configured and the function "shutdown with password" is enabled. The vulnerability which as been assigned the CVE ID 2007-4569 was disclosed on the KDE Announce mailing list.
It affects KDE versions 3.3.0 through 3.5.7. Older or newer versions are not affected. Source code patches are available for KDE 3.5.0 through KDE 3.5.7 and for KDE 3.3.0 through KDE 3.4.2 on the KDE project's FTP server.
Issue 25: Raspberry Pi Handbook 4th Ed./Special Editions
Buy this issue as a PDF
Ubuntu 16.04 LTS released
"Xenial Xerus" comes with a new packages format and several improvements for the enterprise.
Microsoft Visual Studio Code v1.0 is Available for Linux!
Linux users can now download and install the Windows code editor
Open Container Initiative announces Image Format Project
New initiative will address security and interoperability concerns around container technology.
Red Hat Lures Developers with Free RHEL and Container Development Kits
Developers can use RHEL as a development platform without a subscription fee.
Microsoft Brings the Linux Command Line to Windows
Windows users will soon have native access to the Bash shell.
Internet Research Group Proposes Better Email Standard
Improvements to SMTP will provide better guarantee of confidentiality
New Nvidia Driver Offers Wayland Support
Graphics vendor embraces new reality in Linux graphics
Inventor of Email Dies
Pioneer Ray Tomlinson bequeathed the @ sign to billions of Internet users
Microsoft Announces Linux Version of SQL Server
Redmond says its classic database tool will run without Windows
Strange New Attack Lets an Intruder Gain Access Through a Mouse Dongle
New intrusion technique affects most non-Bluetooth wireless mice


text:
Absolutely unprofessional management, unprofessional staff, very dirty salon, hairdresser doesn't know her job. After her color I lost my hair.It's terrible. When I had complaint to manager about this, she said just 'SORRY ".Horrible! I never ever go there more. Girls be careful... if you want to save your hair healthy.
Vada Spa
Today:10:00 am - 9:00 pm
387 Avenue Of The Americas,
New York, NY 10014
(917) 338-3348
Business Details
in Business
- BBB Rating:
- Social Links:
- Visit Twitter Page | Visit Facebook Page
- Hours:
Regular Hours
- General Info:
- Vada Spa is a Manhattan day spa that is located in the Heart of New York City's Greenwich Village. At Vada Spa our services will refresh, de-stress, invigorate and refine your appearance. Our services include couples massages, hair removal, facials and many more. Vada means water; pure, natural and essential for every-one's well-being. Our products embrace the true meaning of Vada and are always all natural and pure. The services are performed by seasoned professional aestheticians, technicians and stylists. It is the aim of Vada to re-vitalize, invigorate and create a new and healthy beautiful you. The atmosphere of Vada is relaxed and trendy. Leave your concerns at the door and enter our oasis.
- Extra Phones:
Fax: (718) 747-3238
- Services/Products:
- * Artificial Lash Extensions * Body Hair Trimming & Bleaching * Body Treatments * Ear Candaling * Ear Piercing * Electrolysis * Facials * Gift Certificates * Hair * Hair Removal * Laser Services * Massage * Monthly Specials * Nails * Permanent Make-up * Spa Packages * Threading * Tinting * Waxing
- Brands:
- * Cynosure Elite Laser System * Helen Seward Hair Products * Pevonia Botanical
- Payment method:
- all major credit cards
- Neighborhoods:
- Downtown Manhattan, Greenwich Village
- Languages:
- English, Russian, Spanish
- Other Link:
- Categories:
- Day Spas, Beauty Salons, Hair Removal, Massage Therapists, Health Resorts
- Other Information:
Price Range : Average
I originally came in for a mani and pedi but as I needed a facial badly I got their mini facial as well. On the way out I started talking to the hair stylist who convinced me that I needed a new style, OK got that too.... Total price=== $99. There is no way I could have gotten this anywhere else in the city and I am thrilled with everything. On the way out I made an appointment for a full facial next month and will definitely be back +++
Wow, I was a little nervous about getting laser service. I usually get wax on my legs and this time the girl in the front talked me into trying a laser patch. It didn't hurt! Emily was really good and knew everything. I came back to get the first session, you need 6 according to what they told me, for it to work. I was really shocked at how little pain there was, almost none compared to waxing. Now I see what all the fuss is about, this laser thing is awesome.
I got my back and shoulders waxed and for the first time I did not get a rash and bumps. I would never write about these things. But I was really amazed! Ira really knew what she was doing so I highly recommend her. There is no such thing as a painless wax everyone that tells you that it is painless either is lying to themselves or you. But This was really not as bad as I expected. I wish I knew about this place before. ++++
I had a fabulous spa experience last week . I was in from out of town and going to a special event that evening. I had a facial, manicure, pedicure, hair and style and makeup. I was so impressed by the service, the products (I wish I could order some of the facial treatment stuff), the obvious caring of the staff. Everyone really cared about the job they did, and were so nice to accommodate my time line (I was really pressed for time) by doing things simultaneously. The prices are als...view moreo unbeatable. I felt pampered! Another thing, I hate pancake makeup (it makes me feel clogged and like my face is dirty and usually ends up in the wrinkles and ages me), however, what you used was wonderful, stayed on all night and didn't cake and get gross. The rest of the makeup stayed on all evening too (in spite of having to run 3 blocks and sweating) even the lipstick.
The place is modest in size and not flamboyantly decorated, but the price, service and products well makes up for that.
I give 4.75 stars.view less


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From a legal perspective integration between the European Community1 and third states in Europe may be seen as depending on questions of the adaptability of law originating within the framework of the EC Treaty to the needs of such integration. These are questions 'that . . . hardly can be solved any longer on the basis of traditional distinctions of international, supranational and constitutional law'.2 For example, they have often been approached by the European Court of Justice on the basis of a constitutional-type definition of the 'external relations' powers of the Community. However, as a recent judgment3 suggests, consistent application of any such definition in the face of the demands made on Community law by growing international interdependence may be problematic.4
In the present book these questions are approached on the basis of an examination of the dynamics of integration law -- trade liberalization, harmonization of law and policy and institutional involvement in these processes. For the purposes of the examination, trade is treated as denoting economic activity generally rather than being limited to exchange of goods. For the same purposes, an analytical distinction is made between the terms of the relevant legal provisions and the legal requirements entailed by such provisions. While the former denote the formal meaning of the provisions concerned, the latter denote their operational meaning. It is the latter which determine the effective role of the law in integration.
In particular, it is trade liberalization requirements, as exemplified in the famous ' Cassis de Dijon' ruling of the European Court of Justice,5 which lie at the heart of the distinctive contribution made by the EC Treaty to integration between Member States. Hence, the embodiment of such requirements in agreements between the Community and third states may be critical as to____________________


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02/14/2012 | Amateur Radio Gets Secondary MF Allocation at WRC-12
It's official -- delegates attending the 2012 World Radiocommunication Conference (WRC-12) have approved a new 7-kilohertz-wide secondary allocation between 472-479 kHz for the Amateur Radio Service. Agenda Item 1.23 had both its first and second readings
Learn More
02/03/2012 | WRC Update: How Are Agenda Items Processed at a WRC?
By Rod Stafford, W6ROD IARU Secretary The procedures used by the International Telecommunication Union (ITU) before and during a World Radiocommunication Conference (WRC) seem complicated. They are somewhat complicated, but they are understandable with a
Learn More
02/03/2012 | Amateur Allocation at 472 kHz Moves a Step Closer to Acceptance
While two hurdles still remain to be cleared, the effort to gain a new amateur medium frequency (MF) allocation reached a major milestone on Thursday, February 2 at the 2012 World Radiocommunication Conference (WRC-12) in Geneva, Switzerland. According to
Learn More
03/23/2011 | Amateurs Assist with Ocean Rescue
At 10:04 AM PDT (1704 UTC) on Monday, March 21, Rex Weinheimer, KC5AGO, of Stonewall, Texas -- a member of Maritime Mobile Service Net (MMSN) -- heard and responded to a weak and broken MAYDAY call. The call was from the sailing vessel Gloria Jean, a 30 f
Learn More
Feature01/04/2010 | ARRL In Action: What Have We Been Up to Lately?
This feature -- including convenient Web links to useful information -- is a concise monthly update of some of the things ARRL is doing on behalf of its members. This installment covers the month of December.
Learn More
12/16/2009 | Hams Help Out with Sea Rescue
When Dave Nicholson, N2AWE, was stranded at sea earlier this month off the Bermuda Triangle, he had no fuel and his 47 foot sailboat had sustained severe damage in a storm. When they learned of his predicament, hams with the Maritime Mobile Service Net (M
Learn More
Feature02/22/2009 | Surfin': Joining Our Public Weather Service
This week's Surfin' discusses the variety of Amateur Radio services related to the National Weather Service.
Learn More


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Rafiqan's Group
A caring lady, Rafiqan stays at home and carries out her responsibilities as a housewife. Besides her household work, she also helps her husband in his dairy business. They both get up early in the morning, get milk from the buffalo, and then her husband goes to the community to sell the milk. In this way, they both generate the income to meet the basic needs of the family.
Rafiqan has applied for a loan from Kiva partner Asasah for her husband's dairy business. Through the loan, he will buy another buffalo that will help him increase milk productivity and also sales.
Rafiqan is hopeful that through the loan investment, her husband's business will improve and he will be able to increase his monthly income as well.
Note: In the photo, the lady with a book (called Asasah Passbook) is Rafiqan.
Additional Information
This is a Group Loan
In a group loan, each member of the group receives an individual loan but is part of a larger group of individuals. The group is there to provide support to the members and to provide a system of peer pressure, but groups may or may not be formally bound by a group guarantee. In cases where there is a group guarantee, members of the group are responsible for paying back the loans of their fellow group members in the case of delinquency or default.
Kiva's Field Partners typically feature one borrower from a group. The loan description, sector, and other attributes for a group loan profile are determined by the featured borrower's loan. The other members of the group are not required to use their loans for the same purpose.
About Pakistan
271View loans »
Success!! The loan was 100% repaid
- Repayment Term
- 13 months (Additional Information)
- Repayment Schedule
- Monthly
- Pre-Disbursed:
- Apr 7, 2011
- Listed
- Apr 14, 2011
- Currency Exchange Loss:
- Possible
- Ended:
- Apr 15, 2012


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Who's No. 1? Ford Says Focus, Toyota Says Corolla
TheStreet) -- Ford (F - Get Report) said the Focus is the world's best-selling vehicle nameplate, while Toyota (TM - Get Report) said it's the Corolla. The controversy began Wednesday after a Ford press release, citing data from Polk, declared that worldwide 2012 sales of the Focus totaled 1,020,410 units. Also, Ford said the Fiesta is the best-selling subcompact car, with 723,130 registrations in 2012."Focus and Fiesta represent the culmination of our One Ford global product strategy," said Jim Farley, Ford executive vice president for global marketing, sales and service, in a prepared statement. "Through One Ford, we're able to bring economies of scale and fantastic value to customers all around the world." Following the Ford release, Toyota said Corolla was the world's top-selling car, according to Reuters . Toyota's Tokyo-based spokesman Ryo Sakai said the Japanese carmaker sold 1.16 million Corollas in 2012 and that "Toyota still sees the Corolla as the world's most popular car," Reuters reported. The Corolla sedan accounted for 90% of the sales, Sakai said, with five other Corolla models accounting for the remaining 10%. Polk counted 872,774 Corolla sales, perhaps excluding the non-sedan units. . "Toyota sold 1.16 million Corolla nameplate vehicles globally in 2012," Toyota spokesman Mike Michels said Monday, in an e-mailed statement to Bloomberg. "Corolla registrations attributed to Polk come up short by nearly 300,000 units. This discrepancy is glaring and we have requested clarification." Ford said that market gains for Focus were driven by consumer demand in China and the United States. It said that China registrations rose 51% last year and accounted for one in four global sales. U.S. Focus sales rose 40% to 245,922. "Since its launch in China in late March of last year, Focus sales continue to strengthen, with the car now ranking as the best-selling passenger car in China in 2012 for the first time ever," Farley said. "With additional manufacturing capacity added last year, we now have a tremendous opportunity to further strengthen our global small car sales in 2013, with sales off to a very strong start already." Follow @tedreednc -- Written by Ted Reed in Charlotte, N.C. >To contact the writer of this article, click here: Ted ReedDETROIT (
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