text:
PHILADELPHIA , Nov. 1, 2012 /PRNewswire/ -- Destination Maternity Corporation (Nasdaq: DEST), the world's leading maternity apparel retailer, today announced that it has entered into a new $61 million revolving credit facility with Wells Fargo Bank, N.A. The new credit facility replaces the Company's $55 million revolving credit facility with Bank of America, N.A., which was due to mature on January 13, 2013. The Company also announced that, as of November 1, 2012, it has repaid the remaining principal amount ( $13.4 million) of its senior secured Term Loan, which was due to mature on March 13, 2013.
Destination Maternity Announces New Credit Facility With Wells Fargo
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text:
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subset: commoncrawl


text:
Well, after a long discussion with my mother, we decided that after delivery, while I'm already in pain anyways, I should get my tubes tied.Ā
I agree with this. I personally think that if one has a child that they might not fully be able to support then they shouldn't have any more children until they can, and what better way to do that then ensure that it won't happen? Birth control fails and so do condoms, so I think this is a pretty good route and it can be reversed.Ā
I suppose if something happened to where in the future this procedure couldn't be reversed and I was ready for more children then I would adopt. I never wanted to have children to begin with anyways, I've always wanted to adopt.Ā
I just don't want to make this mistake again. Obviously, I won't be having sex without being on the pill andĀa condom. Lesson well past learned, but my mother was always on birth control/using condoms and somehow she has five children. (Two are deceased.) We're allĀbirth control whoopsies.Ā
I guess I'm writing this for opinions. What do you think about having something like this done? Do you think that this is really as good of an option as I'm seeing it?Ā


text:
If an enzyme name is shown in bold, there is experimental evidence for this enzymatic activity.
|Degradation/Utilization/Assimilation → Carbohydrates Degradation → Polysaccharides Degradation → Glycosaminoglycan Degradation
|Degradation/Utilization/Assimilation → Polymeric Compounds Degradation → Polysaccharides Degradation → Glycosaminoglycan Degradation
Some taxa known to possess this pathway include : Bacteroides thetaiotaomicron, Pedobacter heparinus, Proteus vulgaris, Streptococcus agalactiae
Expected Taxonomic Range:
Chondroitin sulfate and dermatan sulfate are major components of connective tissue matrix (such as skin and cartilage) in animals.
They are both glycosaminoglycan polymers composed of repeating disaccharide units, each containing N-acetyl-β-D-galactosamine linked by a (1,3) or (1,4) linkage to a uronic acid, β-D-glucuronate or α-L-iduronate, with extensive N and O-sulfation. Sulfation occurs to various degrees at position 2 of uronic acid and at positions 4 or 6, or both, of galactosamine. In addition, the amino group of galactosamine is acetylated
Many microorganisms have enzymes that enable them to degrade glycosaminoglycans [Sutherland95]. This ability is particularly important for soil bacteria, which may depend on connective tissues in animal carcasses as a nutrient source.
There are several steps in the degradation process. It starts with the cleavage of the polymer into smaller fragments, initially tetra- and hexasaccharides, but ultimately disaccharides. The process continues with the removal of the sulfate groups, and ends with the final degradation of the disaccharides into individual sugars, a step that has not been characterized yet.
The lyases that break the polymer to smaller fragments are classified based on the position of cleavage as either endo-lyases or exo-lyases. The endolytic enzyme can produce products of several sizes, although the final product tends to be disaccharides. The exo-lyases cleave dissaccharide molecules from the non-reducing end of the polymer chain [Hamai97]. Some lyases, known as chondroitinase AC, can act only on chondroitin sulfate A and chondroitin sulfate C (that contain β-D-glucuronate), some, known as chondroitinase B, can act only on dermatan sulfate (that contains α-L-iduronate), and some, known as condroitinase ABC, can act on both [Tkalec00, Hamai97].
The lyases act by the removal of a relatively acidic C5 proton of the uronic acid (C5 is the carbon linked to the carboxylic group) followed by the elimination of the hexosamine linked to C4, resulting in the formation of an unsaturated C4-C5 bond on the hexuronic acid moiety of the resulting disacchrides.
Chondroitin ABC lyases may help in the regeneration of spinal cord injuries that were thought for a long time to be incurable. Injection of chondroitinase ABC at sites of central nervous system injury, where a glial scar develops, removes the GAG components of ECM chondroitin sulfate proteoglycans and attenuates the inhibitory effects to axon growth [Bradbury02, Bradbury02, Olson02].
The removal of the sulfate groups is catalyzed by specialized sulfatases that can remove the sulfate groups at either the 4 or 6 positions. The sulfatases have been purified from Proteus vulgaris but the genes that encode them have not been identified [Yamagata68].
Created 10-Aug-2010 by Caspi R, SRI International
Bradbury02: Bradbury EJ, Moon LD, Popat RJ, King VR, Bennett GS, Patel PN, Fawcett JW, McMahon SB (2002). "Chondroitinase ABC promotes functional recovery after spinal cord injury." Nature 416(6881);636-40. PMID: 11948352
Hamai97: Hamai A, Hashimoto N, Mochizuki H, Kato F, Makiguchi Y, Horie K, Suzuki S (1997). "Two distinct chondroitin sulfate ABC lyases. An endoeliminase yielding tetrasaccharides and an exoeliminase preferentially acting on oligosaccharides." J Biol Chem 272(14);9123-30. PMID: 9083041
Olson02: Olson L (2002). "Medicine: clearing a path for nerve growth." Nature 416(6881);589-90. PMID: 11948332
Sutherland95: Sutherland IW (1995). "Polysaccharide lyases." FEMS Microbiol Rev 16(4);323-47. PMID: 7654407
Tkalec00: Tkalec AL, Fink D, Blain F, Zhang-Sun G, Laliberte M, Bennett DC, Gu K, Zimmermann JJ, Su H (2000). "Isolation and expression in Escherichia coli of cslA and cslB, genes coding for the chondroitin sulfate-degrading enzymes chondroitinase AC and chondroitinase B, respectively, from Flavobacterium heparinum." Appl Environ Microbiol 66(1);29-35. PMID: 10618199
Trowbridge02: Trowbridge JM, Gallo RL (2002). "Dermatan sulfate: new functions from an old glycosaminoglycan." Glycobiology 12(9);117R-25R. PMID: 12213784
Yamagata68: Yamagata T, Saito H, Habuchi O, Suzuki S (1968). "Purification and properties of bacterial chondroitinases and chondrosulfatases." J Biol Chem 243(7);1523-35. PMID: 5647268
Fethiere99: Fethiere J, Eggimann B, Cygler M (1999). "Crystal structure of chondroitin AC lyase, a representative of a family of glycosaminoglycan degrading enzymes." J Mol Biol 288(4);635-47. PMID: 10329169
Hashimoto99: Hashimoto W, Kobayashi E, Nankai H, Sato N, Miya T, Kawai S, Murata K (1999). "Unsaturated glucuronyl hydrolase of Bacillus sp. GL1: novel enzyme prerequisite for metabolism of unsaturated oligosaccharides produced by polysaccharide lyases." Arch Biochem Biophys 368(2);367-74. PMID: 10441389
Huang01: Huang W, Boju L, Tkalec L, Su H, Yang HO, Gunay NS, Linhardt RJ, Kim YS, Matte A, Cygler M (2001). "Active site of chondroitin AC lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis." Biochemistry 40(8);2359-72. PMID: 11327856
Huang03a: Huang W, Lunin VV, Li Y, Suzuki S, Sugiura N, Miyazono H, Cygler M (2003). "Crystal structure of Proteus vulgaris chondroitin sulfate ABC lyase I at 1.9A resolution." J Mol Biol 328(3);623-34. PMID: 12706721
Jongkees11: Jongkees SA, Withers SG (2011). "Glycoside cleavage by a new mechanism in unsaturated glucuronyl hydrolases." J Am Chem Soc 133(48);19334-7. PMID: 22047074
Latendresse13: Latendresse M. (2013). "Computing Gibbs Free Energy of Compounds and Reactions in MetaCyc."
Maruyama09: Maruyama Y, Nakamichi Y, Itoh T, Mikami B, Hashimoto W, Murata K (2009). "Substrate specificity of streptococcal unsaturated glucuronyl hydrolases for sulfated glycosaminoglycan." J Biol Chem 284(27);18059-69. PMID: 19416976
Nakamichi10: Nakamichi Y, Maruyama Y, Mikami B, Hashimoto W, Murata K (2010). "Structural determinants in streptococcal unsaturated glucuronyl hydrolase for recognition of glycosaminoglycan sulfate groups." J Biol Chem 286(8);6262-71. PMID: 21147778
Pojasek01: Pojasek K, Shriver Z, Kiley P, Venkataraman G, Sasisekharan R (2001). "Recombinant expression, purification, and kinetic characterization of chondroitinase AC and chondroitinase B from Flavobacterium heparinum." Biochem Biophys Res Commun 286(2);343-51. PMID: 11500043
Sato94: Sato N, Shimada M, Nakajima H, Oda H, Kimura S (1994). "Cloning and expression in Escherichia coli of the gene encoding the Proteus vulgaris chondroitin ABC lyase." Appl Microbiol Biotechnol 41(1);39-46. PMID: 7512814
Shaya08: Shaya D, Hahn BS, Bjerkan TM, Kim WS, Park NY, Sim JS, Kim YS, Cygler M (2008). "Composite active site of chondroitin lyase ABC accepting both epimers of uronic acid." Glycobiology 18(3);270-7. PMID: 18227125
Zhang09d: Zhang Z, Park Y, Kemp MM, Zhao W, Im AR, Shaya D, Cygler M, Kim YS, Linhardt RJ (2009). "Liquid chromatography-mass spectrometry to study chondroitin lyase action pattern." Anal Biochem 385(1);57-64. PMID: 18992215
©2016 SRI International, 333 Ravenswood Avenue, Menlo Park, CA 94025-3493
SRI International is an independent, nonprofit corporation. Privacy policy Disclaimer


text:
yokai butsudan by CuboidalWatch
©2012-2016 Cuboidal
needed to have a quick reference of my monster OCs just for future reference
guess you could call him
If you want more Japanese monster ideas, you should check this book called: Yokai Attack! The Japanese Monster Survival Guide. It's a fun book to read and it has illustrations! Love the oni character~~~
Probably the coolest looking OC's I've had the pleasure of laying my eyes on.
Very cool.
I like the characters and there awesome styles.
I like the characters and there awesome styles.
These guys are awesome! Especially Butsu, really digging that getup.
I love your style.


text:
CMCA Thrift Shop at Hillcrest
Business hours Tuesday - Friday 10:00 a.m. to 4:00 p.m.
~ Shop to help ~
Our thrift store is staffed and operated by volunteers. 100% of our proceeds benefit non-profit charitable organizations located in the Tulsa area. The Thrift store is not going to move as soon as we thought. The new location was not safe as is. We have been asked to stay where we are for now. Keep an eye out here so you can know as soon as we do!! Remember Children's Medical Charities Thrift shop when you have items to donate. We count on the public for that.! Hope to see you here!
Children's Medical Charities Association awarded over $77,500 in grants for 2014!!
CMCA's Thrift Ave resale store is located at the SE corner of 11th and Utica.
CMCA sells new and gently used items contributed by individual donors to help fund and support local children's programs.
We have beautiful seasonal items all through the year.
Great Shopping
You will find amazing items from ladies formal wear to country kitchen finds. We also carry children's clothing, books and toys as well as .
Our greeting card section and special books are a favorite. Other household articles such as bedding, dishes, pictures, picture frames and small furniture can be a great find at a super price. Jewelry, jewelry, jewelry!!
Come see our new and lovingly worn jewelry. Our prices are great!!!
Tax Deductable Forms Provided


text:
Dave Van Horn - Aggies Rainout
Arkansas head coach Dave Van Horn talks ...
Arkansas tight end Mitchell Loewen (89) runs into the end zone ahead of Samford defensive back Jaquiski Tartt (6) during the first quarter of an NCAA college football game in Little Rock, Ark., Saturday, Sept. 7, 2013. (AP Photo/Danny Johnston)
FAYETTEVILLE Arkansas tight end Mitchell Loewen will miss spring practice after suffering a torn ACL, Razorbacks coach Bret Bielema said Wednesday.
Bielema said he's hopeful Loewen, a junior, would be available for Arkansas' season opener Aug. 30 at Auburn. Loewen caught 2 passes for 29 yards last season, including a 24-yard touchdown catch against Samford.
The Lahaina, Hawaii native began his career as a walk-on but earned a scholarship prior to last season. He is one of four tight ends with playing experience on the Razorbacks' roster.
Arkansas is scheduled to begin spring practice next Sunday.


text:
Brunei is about to pass a penal code that would allow people to be stoned to death for having gay sex. [2]
The penal code allows stoning for multiple offenses: rape, adultery, sodomy, extra-marital sex, gay sex, insulting the Quran or Hadith, blasphemy, declaring oneself a prophet or non-Muslim, and murder.
Brunei hasn't conducted an execution since 1957, but this is a part of Brunei Sultan Hassanal Bolkiah [3]'s push towards a stricter interpretation of Shariah law [4].
The United Nations and human rights advocates have condemned Brunei's penal code and have asked the sultan to stop its implementation, as it violates international law.
"We urge the Government to delay the entry into force of the revised penal code [5] and to conduct a comprehensive review ensuring its compliance with international human rights standards," said Rupert Colville, UN High Commissioner for Human Rights.
The new penal code will go into effect on April 22.
[1] http://www.syndigate.info
[2] http://lgbtweekly.com/2014/04/14/un-urges-brunei-to-delay-new-law-mandating-stoning-of-gay-people/
[3] http://en.wikipedia.org/wiki/Hassanal_Bolkiah
[4] http://en.wikipedia.org/wiki/Sharia
[5] http://www.pinknews.co.uk/2014/04/15/un-condemns-brunei-over-new-law-allowing-gays-to-be-stoned-to-death/
[6] http://www.upi.com


text:
Scott Speedster S60 flat bar.
Only thing I could afford. What would be the first thing you would replace? Im thinking next year once the parts I have on it start going out I could maybe upgrade the components and replace the flat bar with a racing one.
Also, I feel EVERY single bump in the road with this, is that because of the frame, forks, seat or what? Or a combination of all three?


text:
Should there be an independent review of the administration of cricket in New Zealand?
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Former captain and selector Dion Nash says New Zealand Cricket's problems are worst at the top, where the board is failing in its duty to lead the game in the right direction.
Asked to run the rule over the state of cricket, Nash said the Black Caps' struggles paled in comparison to the board's performance.
He felt David White was an effective chief executive but lacked strong support and direction from chairman Chris Moller's eight-person board, of which Robbie Hart is the only former international player.
"Any board that needs an advisory panel on cricket-specific matters is no board at all," Nash told said.
"What are they there for if they don't know what they're talking about? It's a joke.
"From the outside - and I'm very much on the outside - what's the plan and where are we going? It looks like we're just reacting the whole time and it looks like the Players' Association is driving things and not the board and not NZC."
Nash felt any review in the wake of the Black Caps' dire showing in Sri Lanka, where they tumbled to their fifth consecutive test defeat this week, should be directed at the NZC governance rather than the team.
On the team performance, Nash said it was a simpler fix.
"They just need to score runs. There's a little cultural issue there . . . that if I was in the team, or a few others like Chris Cairns or Stephen Fleming or Nathan Astle, we would just not put up with guys consistently playing the same shots and getting out.
"They're not learning and that needs to be addressed. Just saying 'That's how I play' is not good enough and not acceptable."
Captain Ross Taylor and Brendon McCullum, the side's best two batsmen and senior men, were the most culpable.
Nash said their presidential-style race for the captaincy after last year's World Cup had caused issues that were still hurting the team. He felt it was time for McCullum to take the reins.
"It's one of the sores that's boiling away, that looks from the outside like it's affecting things. Give Brendon a go and see what he's like under the pressure of it all.
"That whole campaign for the captaincy between those two guys was ridiculous. Captaincy is something that gets bestowed upon you. It's an honour, and it's not something you should be seeking out."
Nash felt the right people were in place in the coaching setup but the messages still needed to be rammed home.
"Shane Bond is a huge asset and they've got to give Mike Hesson time to bed in as coach.
"At times I wonder if he's too close to Brendon. He's a fantastic player and a talent but someone needs to get in his ear and tell him he's not performing well enough and he isn't the top batsman in the world. He's not even the top batsman in our team at the moment, and he's got all the potential to be both but he needs to improve. So does Ross Taylor, so does that whole top five.
"When our best players aren't playing well enough, they're the guys you first need to point the finger at and say: 'You can change this, and you should'."
Nash said that when Fleming became captain in the late 1990s he had a leadership group of about eight players who made the transition easier. There was leadership potential in the current side and he saw some evidence of it among the young bowling attack.
"I see Tim Southee leading right now and he's one of the younger guys and he's doing a fantastic job and he's only 23. He's leading the bowling attack through his actions and demeanour. I bet he doesn't say much at the captaincy meetings but he's a leader, he's right up there.
"And Trent Boult is one of the guys with steel in his eyes. I see anger at the way the team is going. That gives me heart. Not only is he bowling beautifully, but any day soon he's going to take a bagful of wickets. Right now you can see he's angry and it's about time someone got angry."
The second and final test in Colombo starts on Sunday.
- Wellington
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Should bouncers be banned from cricket?


text:
I need please help because at WordPress i am a nooby.
A week ago I "created a Network" for my blogger.(Multi site)
I created afterwards a site "bigcitys.nation.com", so when i created it everything went fine but when i clicked the first time "dashboard" this came up "The requested URL /wp-admin/ was not found on this server."
I want to know why is that.


text:
Isaiah 49:1-6
Psalm 139:1b-3, 13-14ab, 14c-15
Acts 13:22-26
Luke 1:57-66, 80
The Liturgy of the Word applies the second song of the Suffering Servant of Isaiah to John the Baptist. During Holy Week, we read all four songs and saw how they were all fulfilled in Jesus Christ. The first song (42:1-7) e…


text:
Illustration by Andrew Saeger, tHE ARTdept. Hey fellow lushes! Of course you're probably aware there's a big holiday on the calendar next week, but Feb.
Illustration by Andrew Saeger, tHE ARTdept.Hey fellow lushes! Of course you're probably aware there's a big holiday on the calendar next week, but Feb. 14 isn't just about chocolate and cards filled with syrupy sentiment.
The Wino likes to celebrate Valentine's Day by uncorking a bunch of red wine and not just because they tend to taste like a little bit of terrific. Wines of a certain hue are also good for you. Don't take my slightly slurred word for it. The Mayo Clinic freaking says so!
There's enough red wine in the world to fill the Puget Sound, so how do you pick something worthy of sipping with your sweetie on Tuesday?
By cultivating a serious relationship with a wine seller, who you grow to trust over time. Like Emile at Champion Wine Cellar or the crackerjack crew at Esquin or Mike Teer at Soul Wine. Tell 'em what you like and how much you're willing to spend and -- wham, bam -- you're walking out the door with a couple fine bottles under your arms.
I think I've got a crush on a new wine merchant, though I've never met the dude, I picked up a bottle that was a featured pick and it was awesome with a capital AWE. And it was a happy accident.
I was happy houring at Daniel's Broiler on Leschi and my buddies mentioned the market across the street and its wonderful wine selection. After I paid my tab, I did some tipsy retailing and was completely jazzed about the selection at the Leschi Market, from the hard-to-find high-end stuff to some amazing deals.
The Spanish Rioja I picked up has the coolest label and is named Cepasantiguas, which means old vines. And everybody knows that when it comes to wine, older almost always means better. The wine was velvety smooth but far from soft. It had lovely berry flavors and little bit of spice. And it was $12. I'm in love.
The Wino's going to give this wine four out of four brown paper bags, tied up in a pretty pink bow.
Follow Voracious on Facebook & Twitter.


text:
Chubby Link by Capital---GWatch
©2014-2016 Capital---G
Thanks for all the nice comments everyone, for anyone who wants to know I used Zbrush to sculpt this little guy and Photoshop to put the finishing touches on him.
I have also uploaded a close up to my gallery!
He looks so optimistic and happy. <3
EEEEEEE, omg I love him. <3
This needs a toy
Es tan <3 adorable!
He's so cute!
This is so adorable, I just can't
Amazing ;A;
Amazing ;A;
omg I laughed so hard my eyes watered! XD That is so damn cute!
*hugs the living crap out of him*
So cute aww!
this is adorable! I love it, nice work!
lol cute
Can't describe how much I adore this. Wonderful work!
Haha! I love it!
Like the Style and it's very well rendered.
Love it.
Love it.
Came here from Kotaku!
Awesome! It makes me love Link even more.
So awesome and chubby!
Wow! That's cute!
it's soooooo flipping adorable
So adorable.
That is the cutes thing I have ever seen!! XD
I can't stop laughing!!
haha it looks like a mix of legend of zelda and adventure time xD very nice ! this piece just inspired me to try out zbrush myself
i laugh
do i even have repeat what everyone else probably thought?...
"that's cute"
Awesome work!!
Fantastic work! Very cute!
Toon Link let himself go apparently... but he really did good with the hair. Awesome art :3
purdy cute lol
I Frickin Love His Smile! He's so Damn Happy!
Great looking design and nice light and cartoonish look you got in this one. Works like this make me thinking about moving Zbrush from Blender.
This is awesome!
Omg so cute!
Thats Awesome


text:
How do you delete a comment in "conversations" if you realize you don't want it up there?
72 votes
Bryan Kramer shared this idea
Jim Barry shared a merged idea: add the option to delete posts. I posted a comment and it didn't appear so I posted it again. Now there are two identical posts up
bob shared a merged idea: you can add an option to delete the post after 15 to 30 minute please we need it
Josh Reed shared a merged idea: Delete a conversation
Allow me to delete conversations or archive them somehow. I did some text conversations and now I can't delete them.
Under Review · Sarah responded
Currently there is no delete function in Conversations. We'll look at the feasibility of adding one in the future. Thanks!
2 comments
Anonymous commented
Why won't facebook allow you to delete conversations on FB mobile apps..
Stephen Heasley commented
In addition to deleting unneeded comments, would be nice feature if the Suggested post itself can be deleted/rejected, or if it somehow changes when action taken. Currently, post appears the same regardless of 1) inaction, 2) rejection, or 3) retweeted or scheduled.


text:
The Power of Independent Thinking
Love Gov Video Series: Presentation at Draper University
Recorded: Tuesday, November 3, 2015
David J. Theroux, Founder and President of the Independent Institute, presents the idea and concept behind Love Gov: From First Date to Mandate, the award-winning, satirical video series that portrays the federal government as an overbearing boyfriend Scott Gov Govinsky who foists his good intentions on a hapless, idealistic college student, Alexis Smith.
To watch the web series, follow this link
Experts: David J. TherouxType: Other EventIssues: Banking and Finance, Bureaucracy and Government, Business, Civil Liberties/ Human Rights, Collectivism, Corporate Welfare, Culture/ Society, Economic Policy, Education, Energy, Fiscal Policy/Debt, Free Market Economics, Freedom, Government Power, Government Secrecy, Government Waste/Pork, Health Care, Housing, Labor and Employment, Political Ideology and Philosophy, Privacy, Property Rights, Public Health/ Consumer Protection, Regulation and Deregulation, Taxes, Trade, Welfare
Myths of Immigration, Ben Powell on Stossel
Recorded: Tuesday, October 6, 2015
Are immigrants taking our jobs and living off the taxes we pay? Are they criminals? Television personality John Stossel (Host of Stossel on Fox Business Network) interviewed Benjamin Powell, Senior Fellow at the Independent Institute, Director of the Free Market Institute at Texas Tech University, and Editor of the book, The Economics of Immigration.
Experts: Benjamin W. PowellType: TelevisionIssues: Business, Civil Liberties/ Human Rights, Crime, Criminal Justice/ Prisons, Culture/ Society, Drugs (Illicit), Government Power, Immigration, Labor and Employment, Politics, Social Security, Taxes, Welfare
Love Gov on Stossel: "Let's Break Up with Government"
Recorded: Friday, September 25, 2015
Television personality John Stossel (host of Stossel on Fox Business) featured our new satirical, YouTube video seriesLove Gov: "From First Date to Mandate" on September 25th, 2015.
Experts: John StosselType: TelevisionIssues: Education, Government Power
Freedom Act, Patriot Act or Status Quo Act
Recorded: Monday, June 8, 2015
Senior Fellow Ivan Eland appears on RTs CrossTalk program to discuss topics surrounding the US Patriot Act and whether or not Edward Snowden was a hero or a traitor. On a panel with other defense analysts, the US war against terror is debated. The panel discusses whether or not the US government is violating the constitutional rights by collecting metadata of phone calls and emails of US citizens.
Experts: Ivan ElandType: TelevisionIssues: Civil Liberties/ Human Rights, Government Power, Government Secrecy, Privacy
C.S. Lewis on Natural Law and Liberty
Inaugural Presentation: Center for Western Civilization, Berkeley, California
Recorded: Sunday, April 26, 2015
Drawing on C.S. Lewiss varied writingsfiction for both adults and children, non-fiction essays and scholarly treatises, poetry, and extensive correspondence with people from all walks of lifeIndependent Institute President David Theroux presents Lewiss highly developed, Judeo-Christian philosophical insights into our relationship with power and human aspirations.
From his declining an offer of knighthood to his keen essays such as The Humanitarian Theory of Punishment, C.S. Lewiss timeless thinking provides rich insights into how to apply natural-law principles to our world and the challenges we all face today.
Experts: David J. TherouxType: Other EventIssues: Civil Liberties/ Human Rights, Collectivism, Constitutional Law, Culture/ Society, Democracy, Education, Free Speech, Freedom, Government Power, Government Secrecy, Government Waste/Pork, History (International), Law Enforcement, Nationalism, Political Ideology and Philosophy, Politics, Privacy, Privatization, Property Rights, Public Health/ Consumer Protection, Regulation and Deregulation, Religion, Science, Technology, Welfare
Stephen P. Halbrook | Oral Argument at Appeal of Heller vs District of Columbia
Recorded: Monday, April 20, 2015
Research Fellow Stephen P. Halbrook, author of Gun Control in the Third Reich, presents oral arguments in the U.S. Court of Appeals for the DC Circuit in the ongoing appeal of the landmark Supreme Court case of Heller v. District of Columbia. The case affirmed the Second Amendment rights of citizens for lawful purposes such as self-defense.
Experts: Stephen P. HalbrookType: Other EventIssues: Bureaucracy and Government, Civil Liberties/ Human Rights, Constitutional Law, Crime, Criminal Justice/ Prisons, Culture/ Society, Freedom, Government Power, Gun Control, Law Enforcement, Litigation, Privacy, Property Rights, Race Issues, Urban Issues
John R. Graham: Shouldn't Healthcare Be Fair?
Recorded: Monday, November 3, 2014
Independent Institute Senior Fellow John R. Graham proposes a major change to Obamacare that would allow a level playing field for everyone.
To purchase copies of John C. Goodman's book "Priceless: Curing the Healthcare Crisis," click here or call Toll Free 1-800-297-8733.
Experts: John R. GrahamType: TelevisionIssues: Bureaucracy and Government, Free Market Economics, Government Power, Government Waste/Pork, Health Care, History (U.S), Labor and Employment, Regulation and Deregulation
Ivan Eland on Ranking US Presidents
Recorded: Sunday, October 26, 2014
Ivan Eland, Senior Fellow at the Independent Institute, appears on Fox & Friends to discuss his updated version of "Recarving Rushmore."
To order copies of "Recarving Rushmore: Ranking the Presidents on Peace, Prosperity, and Liberty," click here.
Experts: Ivan ElandType: TelevisionIssues: Bureaucracy and Government, Civil Liberties/ Human Rights, Culture/ Society, Defense and Foreign Policy, Democracy, Diplomacy and Foreign Aid, Fiscal Policy/Debt, Freedom, Government Power, Government Secrecy, Government Waste/Pork, History (U.S), Nationalism, Political Ideology and Philosophy, Politics, Regulation and Deregulation, Terrorism and National Crises, Trade


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So i'm modding a bunch of stuff on my old 10/22 to rig it out for ground squirrels (it is already okay but im just having fun with it). I need a new scope for it (the one i have is old, small, and low power). Im thinking of getting the Bushnell banner dusk and dawn in 4-12x40mm off cabelas because it seems sufficient for 20-100 yd. ground squirrel and small game hunts. Its also quite cheap (99.99). My one worry is the 3" eye relief, that seems kind of short. The scopes ive used in the past have been low quality but I want a decent one for my modded 10/22. Would the Bushnell be enough for 100 yd. hunting and less? Is it worth more money for a better scope. I dont think i need a 50mm objective and the eye relief is the only spec thats different for 200$ nikon 3-9x40mmAlso, do you think that 4-12 is overkill for those low ranges. I havent used anything higher than 4x ever, which i know is not enough for 50-100 yd.Last question, can i use any 1" scope ring mounts, i already have the mount from the old scope and see no reason to buy a new one if i dont have to.thanks,Epick
Having trouble deciding a 10/22 scope
Started by Epick , Dec 27 2009 06:07 PM
5 replies to this topic
Posted 27 December 2009 - 06:07 PM
Posted 27 December 2009 - 06:30 PM
I've got a Mueller APV 4-14x40mm on a .17 hmr and now another one on a 10/22. Very pleased with the scope for the money, they run about $120. I've heard a lot of good things about them and I'm very happy with mine. Price wise they are a little cheaper than the cheapest Nikon you can find, but I think they are a little better scope. I wouldn't buy anything cheaper. I've learned the hard way that cheap scopes are well, cheap. You get what you pay for. The Mueller is the cheapest scope I'd recommend for anything, and I'd only suggest it for a rimfire gun. They do make other more expensive scopes, but I've not much experience with them. I'm not much of a fan of Bushnell, or Bushnell customer service. I hear on this site that the 3200 and 4200 scopes are good, but they are several hundred bucks or more. Just looked, Windwalker Outdoors still has the Mueller APV for $115, free sunshade and shipping.Give Kurt a call, he'll fix you up, bought mine from him. http://www.windwalke...p?idproduct=785
Posted 27 December 2009 - 08:54 PM
alright ill check it out, i hesitated to buy the bushnell because i read that you definetly get what you pay for with scopes. for somereason i cant connect to the windwalker outdoors site
Posted 27 December 2009 - 08:55 PM
+1 on the Mueller Scopes. I own one on my 10 22 and have shot others - good value.
Posted 27 December 2009 - 09:06 PM
found it on another site for $115. Is it worth buying the polarized lens cap or not?
Posted 28 December 2009 - 06:34 AM
Considering the fact that you will be experiencing significant bullet drop with a 10-22, a scope with a duplex reticle (as on the Mueller scope) may not be the best choice. I am an advertiser here and I can offer you a scope that is an incredible value for the money. A HAWKE SPORT HD 3 X 9 - 50mm RIFLESCOPE WITH MIL DOT RETICLE so you'll be able to consistently make the longer shots. See it here HAWKE Scope. It is presently on sale and features bright, crisp, clear optics. This is a great scope for the money. Other features: Spring gun rated (so you know it is rugged), 1/4-inch M.O.A. Turrets, Fully Coated HAWKE HD Lens System, 1-inch Matte Black, Anti-Glare Body Tube, Waterproof, Shockproof & Fog Proof, HAWKE Worldwide Warranty. This would be the perfect scope for your 10-22. I am an advertiser here and I frequent the forum. If you are not happy with something you purchase from me, it will be common knowledge. I would not recommend something that I did not think would perform for you. This HAWKE scope is a great value and it's not some cheesie piece of junk.If your budget permits, another great option (also with a Mil-Dot Reticle) specifically designed for the .22 caliber is this scope HAWKE Rimfire ScopeThe above are two great scopes that offer the best in features, optics, performance and value. If you have any questions, drop me a note.
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She did it. Sen. Patty Murray got her fourth term thanks to a big ol' box of fuzzy voter love from King County. You're welcome, Senator. Republican challenger Dino Rossi made the concession call around 6pm. Murray had pizza and gave a lots of hugs. So what now?
She'll be dealing with a Tea Party-buzzed House of Representatives that's eager to repeal the health care law, dismantle financial reforms and privatize anything that's not nailed down. And they'll now have the votes to try and do some of it.
She'll have a humbled president, who will likely somehow find a way to compromise more with the GOP than he has every day he's been in office.
And in her own chamber, the Senate, she'll have folks like Senate Minority Leader Mitch McConnell, who, just hours before she won, laid out to the right wing Heritage Foundation what the one goal of the Republican Party will be from now on: defeating Obama in 2012.
But, we assume that between all that she'll be able to help with the whole 9 percent unemployment, broken health care system and under-performing schools thing in Washington.
And just so folks are clear about the dynamic Murray will be returning to, here's a perfectly executed juxtaposition of President Obama's conciliatory "let's work together approach" versus Mr. McConnell's "dump the Prez" message.


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Our mission: to help people access diabetes technology and support from the NHS – including insulin pump therapy, smart glucose meters and continuous glucose monitoring. We can help you find out what's available in the UK, if it might help you and how to access it. INPUT is a UK charity run by insulin pump users and their families.
Click here to find out where we will be exhibiting in 2016
including INPUT Fusion
"INPUT has been a great supporter of appropriate access and support for insulin pumps for people with Type 1 diabetes. I value their contribution to improving diabetes care." Professor Valabhji, March 2015
Professor Jonathan Valabhji is National Clinical Director for Obesity and Diabetes at NHS England. He is a Consultant Diabetologist at St Mary's Hospital, Imperial College Healthcare NHS Trust in West London and so remains highly active at the clinical coalface. As National Clinical Director he works to ensure that good advice is available for commissioning diabetes care, supported by high quality information including that provided by the National Diabetes Audit.


text:
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text:
Dr. Siddique's Experience
- Internal Medicine
- Infectious Disease Medicine
Board Certifications
- Internal Medicine
- Abscess Incision and Drainage
- Bacterial Infections
- Fungal Infections
- HIV (Human Immunodeficiency Virus)
- Infection Due to Mycobacterium Marinum
- Infections
- Pneumonia
- Prosthetic Joint Infections
- Sexually Transmitted Diseases (STDs)
- Ulcer
Background Check for Dr. Siddique
Malpractice Claims not available
- Healthgrades does not collect malpractice information for Oklahoma.
- No sanctions history found for the years that Healthgrades collects data.
0 Board Actions
- No board actions found for the years that Healthgrades collects data.
Awards & Recognitions
Education & Training
Medical School
- Dow Medical College-Civil Hospital Karachi
- Graduated in 2005
Internship Hospital
- Lincoln Med & Mh Ctr
- Complete in 2009
Residency Hospital
- Lincoln Med & Mental Hlth Ctr
- Complete in 2011
Fellowship Hospital
- Drexel University College Of Medicine
- Complete in 2013
Languages Spoken by Dr. Siddique & Staff
- English
- Hindi
- Urdu
10 Steps to Pick the Right Doctor
Whether you need a primary care doctor or a specialist, these 10 steps will ensure you find the right doctor for you. View Slideshow


text:
Bellatrix Exploration Ltd. has re-worked the terms of its latest share sale, proving investors will not lunge at every deal in a hot energy market.
On Tuesday the oil and gas company set out to raise $250-million shares at a price of $9.75 each. One day later, both the size and the price were revamped. Bellatrix is now looking to raise $150-million at $9.50 per share.


text:
CellulitisEn Español (Spanish Version)
Cellulitis refers to an infection of the skin that may spread to tissue just beneath the skin's surface. It may occur anywhere on the body, but most commonly affects the face or lower legs.
Cellulitis is usually caused by a bacterial infection. The infection may come from bacteria that normally lives on the skin or bacteria from other sources. The bacterial infection may be caused by:
- A minor injury to the skin, such as a cut, scratch, blister, puncture, or bite, that becomes infected and spreads into the surrounding skin
- Chickenpox blisters that open up and become infected with bacteria
- Injuries that occur in natural bodies of water that become infected with germs found in the water
- A cut or abrasion that becomes infected by food bacteria while handling fish, poultry, eggs, or meat
- Bacteria that enter the body through surgical wounds or a catheter in a vein
- Infection in a person with diabetes or a weakened immune system
- Bacteria spreading from an upper respiratory or ear infection
- Impaired circulation (tends to cause recurrence of cellulitis)
Puncture Wound
© 2008 Nucleus Medical Art, Inc.
Risk Factors
A risk factor is something that increases your chance of getting a disease or condition.
Risk factors include:
- Insect, animal, or human bites
- Diabetes
- Weakened immune system, such as AIDS
- Alcoholism
- Chronic use of steroids
- Kidney and liver failure
- Surgical procedures
- Poor circulation or peripheral vascular disease
- Swelling or fluid retention
- Intravenous drug abuse
- Burns
- Exposure to fish, meat, hides, shellfish, poultry, or eggs
Symptoms may begin within hours or days and can include:
Skin inflammation that begins in a small area and spreads. This includes:
- Redness
- Pain or tenderness
- Swelling
- Warmth
- A red streak (possibly)
- Swollen lymph nodes
- Fever or chills
- Fatigue
- Headache
- Cellulitis near the eyes may cause pain with eye movements and should be treated urgently
The doctor will ask about your symptoms and medical history, and perform a physical exam. Expect to answer questions about how the wound occurred and exposure to animals or natural bodies of water. Your skin will be closely examined. Using a colored pen on your skin, the doctor can mark the border of the cellulitis to monitor its progress.
Tests may include:
Wound culture—a sterile applicator swabbed across the area and sent to a lab to be tested for bacteria and type of antibiotics to use in treating the infection. (This test is rarely, if ever, performed anymore since the bacteria on the swab will reflect the bacteria that colonize our skin normally and, hence, the test is not useful.)
Blood tests—to help determine the severity of the infection
X-rays , bone scans, or CAT scans—to check for gangrene under the skin or evidence that the infection has spread to the bone
The treatment goal is to eliminate the infection and reduce discomfort. Most cases of cellulitis resolve after a week or two of treatment. An infected wound can be cleaned and any dead tissue removed. If a collection of pus (called an abscess) is present, it can be drained. Severe cellulitis, cellulitis in a diabetic or immune suppressed person, or an infection on the face may require hospital care.
Treatment includes:
Antibiotics may be taken by mouth or injected into a muscle or vein, depending on the severity of the infection. Take the entire prescription as directed until all the medicine prescribed is used. Otherwise, the infection may return.
Supportive Care
This may include resting in bed or elevating the infected area higher than your heart. The doctor might recommend applying warm or cool compresses to the area. Change your dressings as directed by your doctor, and protect your skin from additional injury. Do not scratch or rub the area.
To reduce your risk of getting cellulitis:
- Keep your skin clean
- Moisturize dry skin with lotion
Avoid injury to the skin
- Wear protective gear when participating in sports
- Wear long pants and long-sleeved shirts when hiking
- Wear sandals when at the beach, rather than going barefoot
- Be careful around animals, treat pets with respect to avoid bites
- If you or your child has not had chickenpox, talk to your doctor about getting vaccinated
- Do not swim in natural waters if you have cuts or sores
- Try not to cut yourself during fishing or other water sports
If a small cut, bite, or other injury occurs, carefully tend to the wound.
- Clean cuts or scrapes with soap and water
- Apply antibiotic ointment
- Cover with a bandage or dressing
- Do not scratch wounds
- Call the doctor immediately if the area becomes red or inflamed
- Seek prompt medical care for larger wounds or bites
- If your legs tend to swell, elevate them several times a day and wear support stockings
- Get recommended vaccines for children and adults
American Academy of Dermatology
National Institute of Allergy and Infectious Diseases
Canadian Dermatology Association
Health Canada
American Medical Association website. Available at: http://www.ama-assn.org/ .
Cecil Textbook of Medicine . 21st ed. WB Saunders Company; 2000.
Clinical Dermatology . 3rd ed. Mosby-Year Book, Inc.; 1996.
Conn's Current Therapy 2001 . 53rd ed. WB Saunders Company; 2001.
Griffith's 5-Minute Clinical Consult . Lippincott, Williams and Wilkins; 2001.
Harrison's Principles of Internal Medicine . 14th ed. The McGraw-Hill Companies; 2000.
Principles and Practice of Infectious Diseases . 5th ed. Churchill Livingstone, Inc.; 2000.
Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections. Clin Infect Dis . 2005; 41: 1373-406.
Last reviewed November 2007 by Ross Zeltser, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
Copyright © 2011 EBSCO Publishing All rights reserved.


text:
ProjectsBranding Editorial Exhibition Furniture Graphics Interactive Interior Other Packaging Print Product Retail
Design Art London becomes Pavilion of Arts & Design
This year's Design Art London fair has been renamed the Pavilion of Arts & Design London, and will feature a stronger decorative art element.
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Registration only takes 2 minutes. Enjoy full access to the latest news, views and inspiration from the heart of the design industry.Register now


text:
Editor rating : 8
Price: 56,900
Editor rating : 8
Price: 24,999
Editor rating : 8
Price: 14,999
Editor rating : 7.5
Price: 89,900
Editor rating : 7.5
Price: 39,990
Update: According to a Korea Times report, Samsung is also going to file a patent complaint against Apple's new iPhone. The report says,
"It's true that Samsung Electronics has decided to take immediate legal action against the Cupertino-based Apple. Countries in Europe and even the United States ? Apple's home-turf ? are our primary targets,"said an industry source.
Apple's new iPhone is out tomorrow but the Cupertino tech giant's flagship device could face an import ban if tech company HTC gets its way.
HTC wants the new iPhone and the current 4G LTE iPad banned, because its says Apple infringed an LTE patent owned by HTC. According to The Register, "Apple is subject to an ongoing investigation by the the International Trade Commission (ITC) under Judge Thomas Pender, after Taiwanese company HTC filed a complaint in August 2011."
ZDNet reports that"HTC filed this lawsuit against Apple for infringing on two patents it owns for LTE connection methods. HTC acquired the patents from ADC Telecommunications Incin April 2011."
The new iPhone is likely to come with 4G internet with LTE or Long Term Evolution, which is a standard for wireless communication of high-speed data for mobile phones and data terminals.
According to this Bloomberg report, ITC judge, Pender has refused to quash HTC's patents as invalid, stating that"I don't care if they bought these patents to sue you or not. They are a property right."
Bloomberg's report also says, that initially HTC had alleged that Apple violated five of its patents which it acquired from Google. But "Pender threw out that part of the case, saying HTC didn't have adequate ownership control under the terms of its agreement with Google. "
For all the latest iPhone 5 rumours click here.
4G, Apple Inc., iPad, iPhone 5, TechWars
SMARTPHONES Reviews
Huawei Honor 4X review: Battery life is good, but there are better options under Rs 10,000
Lenovo A6000 review: A good entry level phone with a great display but average camera
HTC Desire 526G+ Review: A good budget smartphone, but competition has the price advantage
NOTEBOOKS Reviews
Asus EeeBook X205TA review: For students on a budget; but low storage and no USB 3.0 port are downers
Asus ROG G551JK review: At Rs 82,999 offers a good package, but there is scope for improvement


text: Galesburg Galesburg Looking to Improve Pension Funding By Rich Egger • Jan 31, 2012 Galesburg Mayor Sal Garza said the city is developing a strategy to avoid the same pension system headaches plaguing the state. Illinois has billions of dollars in unfunded pension liabilities. While Galesburg's obligations are nowhere near those amounts, Garza is concerned that the police and fire pension systems are receiving less than 60% of what they should be getting from the city. The city's IMRF (Illinois Municipal Retirement Fund) is at 90%, and Garza would like to bring the police and fire systems up to that level. Pages« first ‹ previous … 3 4 5 6 7 8 9 10 11


text:
Star of David Wallhanging
Source: Babycenter Community
Mom Rating
Ages: Baby
In: Arts & Crafts , Holidays
Instructions:1. Chanukah is a time when Jewish people give gifts such as gelt (coins), play games, and celebrate a small group of heroes, the Maccabees, who defeated a mighty empire. Find out more about this celebration of lights and its symbols. Then create this Star of David wallhanging for yourself or a friend.
2. Cover your art area with newspaper. Paint 18 large craft sticks using Crayola Washable Kid's Paint and So Big Brushes. Air dry.
3. With Crayola School Glue, attach three sticks together to form a triangle. Mix 5 more triangles the same way. Air dry.
4. To form a six-pointed Star of David, lay one triangle pointing up. Lay the other triangle on top of the first with point facing down. Glue together. Repeat to make two more stars. Air dry.
5. Use your imagination and Crayola Glitter Glue to decorate your three stars. Air dry.
6. Tie ribbon or yarn to the top of one star to form a hanger. Tie your other stars to it with more ribbon. Hang your wallhanging where friends and family can enjoy it!
Tags: arts , arts and crafts , children , creative , decoration , family , hanukah , holiday , star
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text:
Distances given are in a straight line from the centre of Yardley Wood but travel routes may be longer.
1.9 Miles
1 Worcester Way, Off Dog Kennel Lane, Shirley, Solihull B90 4JX
Sunrise of Solihull has a beautiful, homelike interior and a large garden to the rear, with residents enjoying all the comforts of home. The home also offers a wide range of daily activities, including trips to local attractions on the minibus. Residents… more
Group / Provider:
Sunrise Senior Living
Care provided for Alzheimer's
1.1 Miles
326 Haunch Lane, Kings Heath, Birmingham B13 0PN
Cole Valley Nursing Home, located in the Kings Heath area of Birmingham, is a versatile service that welcomes many specialist needs. Care workers have robust qualications in conditions like dementia and sensory impairment, while the interior is suited… more
35 Highfield Road, Hall Green, Birmingham B28 0EU
1.1 Miles
251 School Road, Yardley Wood, Birmingham B14 4ER
0.4 Miles
512/514 Stratford Road, Shirley, Solihull B90 4AY
1.7 Miles
1651/1653 Stratford Road, Hall Green, Birmingham B28 9JB
1.0 Mile


text:
Gameboy Color Games
Trick Boarder Cheats for Gameboy ColorHome / Gameboy Color /
This page contains Cheats for Trick Boarder organized by sections for Gameboy Color. This game has "Sports" as genre, made by Natsume, released on Jun 14, 2000. If you can't find a hint or secret in our list, then please check this page periodically for the latest updates.
Boxshot & Details
- Developer: Natsume
- Publisher: Natsume
- Genre: Sports
- Release: Jun 14, 2000
- ESRB: Everyone
Sorry No Cheats Yet!
If you know cheats, secrets, hints, glitches or other level guides for this game that can help others leveling up, then please Submit Your Cheats and share your insights and experience with other gamers.
Stuck in this game? Set a specific, clearly defined question and let other gamers answer your question or view answers to previously asked questions. If you think you are an expert then please try to help others with their questions.
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text:
Please tell me that my 6 month old is not the only one who is determined to be walking. She is constantly pulling herself up on things and is walking along the sofa as I type this. I keep telling her to roll around on the ground and enjoy being a baby but she is determined to go go go. She was crawling very very early, now this... HELP
surfing the sofa
Wife to Garry and Mom to Gabriel 08-20-08 (T21 + AVSD repair 02/06/09), Isabella 02/17/10
Comments (10)
poor mama. i bet you're tired. my little man is still army crawling. that's plenty for me, i'm constantly racing him to things.
Sara (26) <3 Zach (29)
Tyson (2/22/10) Colt (8/17/12)
We're in the same boat over here. She wants to walk soo bad I think just to keep up with her big sister She's crawling on all fours tummy off the ground and she's fast and now started pulling herself up on anything she can reach.Yesterday she wasen't paying attention chewing away on one of her toys with both hands and just let go and just stodd there for a couple seconds I was speechless..So not ready for the moving baby phase. ODD didnt' walk till like 13 months!!
Oh my gosh, i am so with you. I am exhausted from running after and repositioning my little man. In addition to the sofa, he enjoys using the entertainment center, the bookcase, and anything else he can get his hands on...including me and the dog to pull up on. I have got to get some new toys because I think he is just bored!
He has been crawling for the past month or so and has gotten super fast and sneaky...I call him my little maniac man.
OMG they are so little to be doing that!! Over achievers! Thankfully Elsa is still just rocking on all 4s.
Bre�- mommy to 2 gorgeous girls - Cameryn Mikel (3/9/06) and Elsa Claire (2/12/10)!
My little baby is doing the same thing. She likes to pull up on her toy basket and play with all her toys. It stinks, she is always on the go!
Mommy to Little Miss Anabelle-2/23/2010
My ds is still just army crawling as well but he wants to see what is under the sofa and has gotten stuck a few times!
Mine army crawls as well, on the bed..she walks in her walker forwards and back but we have tile all over the place so Im afraid to put her on the floor and for her to fall and hit her head...I really wish we had carpet.
Erin...priceless photos by the way!!
Thanks, it is nice to know I am not the only one. My son is delayed because of having Down syndrome so it is completely crazy to me that Isabella is trying to walk... it is like having twin 9 month olds around my house. Gabriel learned to walk just after Isabella was born... They are good about running in opposite directions just to keep me on my toes!
Wife to Garry and Mom to Gabriel 08-20-08 (T21 + AVSD repair 02/06/09), Isabella 02/17/10
Learn more
Look how far your child has come.
Review your child's growth milestones.
Read about 6 years 1 month : Week 3.
Your growing child
Your 6-year-old: Power plays
Your 6-year-old: Bedtime battles
Your 6-year-old: Eye problems
Your 6-year-old: Handling accidents
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What's next for your growing child?
Get a glimpse of what's to come.
Read about 6 years 3 months.


text:
Former Natchezian bags 900-pound kudu, trophy fish in Namibia
NATCHEZ — In just 15 years of hunting, Natchez-native Darcel Angelloz has already accumulated a list of trophies that any lifetime hunter would cherish.
In June, Angelloz traveled to Namibia, Africa, and added a kudu and a warthog to a list that already included a red stag, an alligator and a nilgai (an Indian antelope that was brought to Texas).
"I think the sheer size of the animals (that you hunt in Africa) makes it exciting," Angelloz said. "You just don't realize the size."
This summer's trip was the second time Darcel and her husband, A.J., traveled to Namibia, and each time they have come back with wonderful success stories.
"We went five years ago, and we loved it so much we went back," Darcel said. "The first time, we went on a trophy hunt and my husband was able to bring back a zebra and a warthog. I did some me-hunting this time."
The couple stayed with a family that they met on their first trip, Peet and Nadine Vermaak, and Darcel said hunting in Africa is like hunting in another world.
"There are warthogs crossing the road, and we had kudus jump over our truck," she said. "We even saw a spitting cobra. The biggest thing is you are driving down the road and a giraffe can be right on the side of the road."
The couple, who now live in Grosse Tête, La., even hit the rivers and navigated their way through crystal-clear water littered with hippopotami and crocodiles for Darcel to reel in a massive tiger fish.
"It weighed about 17 pounds," she said. "They don't come that big very often, and I didn't even realize what I had on the line. Tiger fish is their trophy fish. It's the main thing you go for, and they don't eat them, they mount them."
One of the benefits of African hunting and fishing is the excellent meals that result from the trophies, Darcel said.
"Kudu tastes better than any piece of meat I've ever had," she said. "They had bream in the Okavango River that weighed 3 to 7 pounds. They were gorgeous and tasted good too."
A.J. introduced Darcel to hunting when they started dating 15 years ago, and the couple started small with squirrel, duck and goose hunts. They moved on to alligator, deer and Darcel killed a red stag on their fifth anniversary.
Darcel compared the terrain of Namibia to that of south Texas.
"There's a wide range of land forms," she said. "There's mountains, rivers and dunes. We hunted game more in the sand dunes. We stalked. We were mostly looking at tracks in the sand to pick out an animal, and then we had a tracker that would track that animal."
But hunting big game in Africa is something that Darcel never expected to do when she was growing up in Natchez.
"I think Africa (is my favorite place to hunt)," she said. "Not in my wildest dreams would I have thought coming from Natchez that I would have gone to Africa not once but twice. The most beautiful thing you can see is an African sky at night. There are not a lot of trees and no pollution, so you see a million stars. It's just breathtaking. We've built a bond of friendship with our African family, and we stay in touch and send packages. We hope to go back in the next year or two."
Darcel said A.J. still has several targets left on his list that he hopes to bag on the next trip.
"My husband wants to get a lion or leopard," she said. "That's what he really wants to go for. Back in 1996, before we met, he killed a cape buffalo. Now he wants to get a lion or leopard — a big cat."


text:
Publicis Healthcare Communications Group Announces Nathalie Le Bos Appointed Chief Financial Officer
NEW YORK, Jan. 17, 2013 /PRNewswire/ -- Publicis Healthcare Communications Group (PHCG), the largest health-oriented agency network in the world, today announced Nathalie Le Bos was appointed Chief Financial Officer. Le Bos assumes the role previously held by Ann Garreaud, who was recently appointed Global Chief Financial Officer, Publicis Worldwide in Paris, France. PHCG is a division of Publicis Groupe and manages top-tier brands including Digitas Health, Saatchi & Saatchi Health, Razorfish Healthware, and Publicis Life Brands that specialize in promoting innovative solutions in healthcare. (Photo: http://photos.prnewswire.com/prnh/20130117/NY44285 )In her new role Le Bos will oversee and strengthen PHCG global financial functions and ensure the network continues its strong growth pattern. A seven-year veteran of Publicis Groupe, Le Bos recently served as Chief Financial Officer, Europe for PHCG. She also served as Operations Control Director for Publicis Worldwide, where she was instrumental in strengthening European operations. Prior to her tenure at Publicis, she worked for TEQUILA (an Omnicom Group company) as Chief Financial Officer and for the Havas Group in several roles. Nick Colucci, President and Chief Executive Officer of PHCG, said, "Nathalie was an outstanding CFO for our European operations during a challenging economy. I am fortunate to have her join my executive leadership team at the PHCG global headquarters. Her unique perspective and experience will prove invaluable as we continue to increase profitability and efficiencies for our clients across the globe." "PHCG continues to transform itself to ensure we offer the very best to our global clients. I look forward to working closely with Nick and the rest of the leadership team to continue PHCG's strong financial performance," Le Bos said. About Publicis Healthcare Communications Group Publicis Healthcare Communications Group (PHCG) is the largest health-oriented agency network in the world. A division of Publicis Groupe, PHCG manages top-tier agencies specializing in promoting innovative solutions in advertising, medical education, sales and marketing, digital, market access, and medical and scientific affairs. PHCG is dedicated to creating experiences that compel action, change lives, and amplify business outcomes. With nearly 5,000 employees, PHCG manages 10 agency brands through 58 offices located in 11 countries. PHCG's global brands are Saatchi & Saatchi Health, Publicis Life Brands, Digitas Health, Razorfish Healthware, Discovery, Medicus International, and Publicis Touchpoint Solutions. Web: www.publicishealthcare.com Facebook: www.facebook.com/publicishealthcare Contact: Rosemary Abendroth Global Communications Director, PHCG Phone: +1.212.468.3438 Mobile: +1.917.650.3567 Email: email@example.com
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Every baker needs to have some good frosting recipes that they can whip up at any time to finish off a batch of cupcakes or a layer cake. Frostings, while they don't often get the spotlight the way the cake recipes do, are a crucial component of a dessert because they add moisture, flavor and give just the right finishing touches to draw someone in ... Read More »
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Making dessert doesn't mean that you always have to turn on the oven and do some baking. There are all kinds of no-bake desserts out there to choose from – and "no-bake" encompases a lot more than a box of Jell-o pudding mix. Bakeless Sweets: Pudding, Panna Cotta, Fluffs, Icebox Cakes, and More No-Bake Desserts is a cookbook that includes all kinds of no-bake desserts, ... Read More »
Bake it in a Cupcake
A cupcake is a treat that delivers a lot of flavor in a small, single-serving package. They're usually dressed up with sprinkles or other pops of color on top, but when there is a surprise inside the cupcake – such as a dollop of chocolate or marshmallow filling – it makes it that much more delicious. In Bake it in a Cupcake, you'll find dozens ... Read More »
Savory Pies
When you think of a pie, you might picture a fragrant apple pie or a rich chocolate cream pie before you think of a chicken pot pie, but savory pies are just as delicious as their sweeter counterparts. Savory pies offer an almost endless number of options for fillings, including meat, cheese and vegetables, and can be adapted to suit any occasion, from appetizers to ... Read More »
Simply Sensational Cookies
The bar for home cooking and baking has been raised in the past several of years, with more and more people starting to bake and cook actively as a hobby, rather than just cooking to eat. People are using more complex recipes, looking for better and bigger flavors and wanting recipes that deliver a "wow" factor of some kind instead of just an "it's ok." ... Read More »
Classic Snacks Made from Scratch
When you walk down the snack aisle in the grocery store, you'll see all kinds of snacks and treats that bring back memories of weekend cartoons and bagged lunches. You might not always buy these treats on a regular basis these days, but you probably still have a soft spot for them because of the memories that they bring up. One of the reasons that ... Read More »
The Secret Lives of Baked Goods
The Secret Lives of Baked Goods is another book from Jessie Oleson Moore, the author of both the book and blog Cakespy, and it features the histories of some of the most beloved baked goods that we make. The stories attached to all of the recipes on the book describe how the recipes and and their components evolved over time into the very recognizable treats ... Read More »
Make Your Own Soda
Simple syrup is a mixture of equal parts water and sugar that many home cooks and bakers are familiar with. It's a versatile syrup that can be used for sweetening all kinds of things in the kitchen, but it is especially useful when it comes to sweetening drinks. The only problem with simple syrup is that it is very plain, so the drinks that you ... Read More »


text:
White Lake Wetlands Conservation Area fishing permits now available
Permits available to 100 anglers, good between March 15 and Aug.
February 06, 2013 at 10:00 am | Mobile Reader | Print
|Courtesy FALSERIVERRAISED on Louisianasportsman.com
Only 100 permits will be granted through the lottery, and they are valid between March 15 and August 15, the LDWF said.
Completed applications must be received by LDWF by close of business on Feb. 22, the LDWF said.
Applications can be obtained by calling 225-765-2812 or online at http://www.wlf.louisiana.gov/refuge/white-lake-wetlands-conservations-area.
There will be a $5 administrative fee for all applicants in form of check or money order made out to the LDWF. Winning applicants will have the opportunity to purchase a $40 permit to fish the WCA.
Only one application per person will be accepted, and submitting more than one application will be considered grounds for disqualification.
Engines used on the property will be limited to 40 horsepower or less. Fishing will only be allowed in the Florence Canal and its associated oil-field location canals. There will be no fishing in the WCA marshes, the main camp canal or any other areas marked "No Fishing." Permitted anglers
will be given a map of the WCA.
Lottery participants can mail there applications to Lake Fishing, P.O. Box 98000, Baton Rouge, LA 70898, or dropped off in to Room 422 at the Department of Wildlife and Fisheries Headquarters Building at 2000 Quail Drive in Baton Rouge.
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Hello everyone,
Recently I did INfushion cloning of a 4.2kb insert into a 8.1kb plasmid.
I picked 6 colonies and did a colony pcr (using the same primers I used for INfushion) and ran the products on a gel.
So for the gel I did not see any bands at 4.2kb, but I do see multiple bands in each lane with the "highest" band I see at 1.0kb and multiple bands below that.
I'm not sure if this means my colony pcr did not work? or if I didn't successfully clone my insert?
Submit your paper to J Biol Methods today!
Cannot see insert with colony pcr
Started by Smog187, Dec 02 2012 05:51 PMColony PCR Cloning
6 replies to this topic
Posted 02 December 2012 - 05:51 PM
Posted 03 December 2012 - 11:20 AM
It sounds like it didn't work. Use the plasmid sequencing primers for confirmation of the insert, it is much more reliable and less likely to pick up unligated insert off the plate.
Posted 03 December 2012 - 03:50 PM
Or use one on the plasmid backbone and a second on the insert. Make sure you are using very small numbers of cells. Touch a tip to the colony, scrape in 100 ul of water, mix, use 1 ul as template in your reaction.
Posted 03 December 2012 - 06:10 PM
Thanks for the replies: When I did the colony PCR I used the same primers I used for the INfushion reaction, so "hopefully" the only product being made is the insert.
Posted 03 December 2012 - 06:14 PM
The problem with this approach is that sometimes there is sufficient PCR product left over from the ligation and transformation to allow PCR to amplify it from the plate, without the colony having a plasmid containing the insert. The vector primers or (my preference) the vector + insert primers will not amplify that fragment. It will only amplify at the correct length a successful ligation.
Posted 04 December 2012 - 08:13 AM
So I didn't pick a colony directly from the plate. I did a re-streak of my colony, and picked a new colony from that plate.
Posted 04 December 2012 - 11:21 AM
In that case, it definitely sounds like the ligation failed.
Also tagged with one or more of these keywords: Colony PCR, Cloning
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text:
Type: Improvement
Status: Closed
Priority: Trivial
Resolution: Won't Fix
Affects Version/s: None
Fix Version/s: 0.6
Component/s: None
The SlopeOneRecommender has by far the best RMS of all of the online recommenders in Mahout (that I've found). Unfortunately the implementation also uses much more memory and is unuseable on my laptop.
This patch optimizes memory (and speed) by folding FastByIDMap<RunningAverage> into one class: FastByIDRunningAverage. This is what it sounds like: a Long-addressable array of running averages (and optionally standard deviation).
- All
- Comments
- Work Log
- History
- Activity
- Transitions
MAHOUT-824.patch includes the whole project.
MAHOUT-824.short.patch includes only additions to the utilities. FastByIRunningAverage and some fixes to FullRunningAverage&StdDev, and unit test enhancements.
The new MemoryDiffStorage2 is revamped to use FastByIDRunningAverage. The problem is that SlopeOneRecommender gives different RMS evaluation numbers on real data. The unit tests match- I've added a bunch more unit tests trying to track down the problem. Only with real data is there a problem.
I'm giving up for the nonce. SlopeOne is so much better that I still think it is worth optimizing, but I've run out of steam.
FastByIDRunningAverage is tight and could be used in other places, so I've packaged it as a separate smaller patch.
I agree that slope-one is surprisingly effective, though storing all item-item diffs is expensive. The good news is that almost all item-item diffs carry virtually no info; they're noise. So, I think there's a much better way to dodge the memory constraint: prune the diffs. That can get you much farther than even optimizing away object overhead.
See the constructors that let you cap the number of diffs stored. It can be reasonably smart; it throws out data based on standard deviation of the diffs.
So, I'd prefer to not yet add such a big amount of copy-and-paste. (And, see below, as you say, I don't think this quite works either, or at least there is some evidence it changes behavior.) I think it's fine work though and worth having in a patch; if it's really popular, well there's nothing terribly wrong with it, just duplicative.
For the rest of the code –
I am happy to add more constructors for the running averages in general, sure, plus tests. I think some of the tests need a fix – for example the copy constructor test doesn't test a copy.
I can add the FastByIDMapTest. The copied keySet/values tests don't test those methods, really but I can remove them.
I am not sure why the slope-one tests would need to be changed – this suggests there's something about the changes that might have introduced a bug. I might have to peel some of that back if it looks like the case.
Likewise, I am not sure why the IR stats eval would have changed; this ought not affect anything there.
I would in general not want changes that make fields public or protected.
Marking "WontFix" but really, part was committed. The rest would have to be fixed up to pass tests first, and we'd probably want more evidence it's justified over the existing pruning methods.
Integrated in Mahout-Quality #1077 (See https://builds.apache.org/job/Mahout-Quality/1077/)
Part of
MAHOUT-824 – some additional tests
srowen : http://svn.apache.org/viewcvs.cgi/?root=Apache-SVN&view=rev&rev=1178133
Files :
- /mahout/trunk/core/src/main/java/org/apache/mahout/cf/taste/impl/common/FullRunningAverage.java
- /mahout/trunk/core/src/main/java/org/apache/mahout/cf/taste/impl/common/FullRunningAverageAndStdDev.java
- /mahout/trunk/core/src/test/java/org/apache/mahout/cf/taste/impl/common/FastByIDMapTest.java
- /mahout/trunk/core/src/test/java/org/apache/mahout/cf/taste/impl/common/RunningAverageAndStdDevTest.java
- /mahout/trunk/core/src/test/java/org/apache/mahout/cf/taste/impl/common/RunningAverageTest.java
- /mahout/trunk/core/src/test/java/org/apache/mahout/cf/taste/impl/recommender/slopeone/MemoryDiffStorageTest.java
Sure, this is fine.
MemoryDiffStorage exposes the fact that it uses the RunningAverage(AndStdDev) classes. This was a vexing implementation leakage, and is why I had to add new constructors for FullRunningAverage(AndStdDev). If I went after it more, I would correct this.
Anyway- is there a paper somewhere that defines the error loss for dropping samples in processOneUser? Is there a better subsampler than 'stop after the first N entries'?
I don't have a paper; I am suggesting however that such pruning can even improve the result. A diff based on 1 user is different than one based on 100 users' data. The pruning indeed appears dumb. Ideally it would at least throw out a "poor" diff in favor of a new one that's better. But, under this scheme, it's low-count diffs that are worst. And so a new 1-count diff is by definition among the worst. So it's as optimal a strategy as anything. Put another way, if you haven't seen an A-B diff at all in millions and millions of users, it's unlikely to be of consequence.
For any method that doesn't have good regularization, trimming helps avoid over-training. Slope-one and all of the correlation methods have zero regularization and are seriously susceptible to coincidence. LLR trimming is kind of the simplest level of regularization. Methods like latent factor log-linear have serious and real regularization and probably don't need trimming.


text:
Nikon D800E holds its ground vs Pentax 645D
Started Dec 4, 2012 | Discussions thread
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spqr_ca • Contributing Member • Posts: 707
Re: Nikon D800E holds its ground vs Pentax 645D
henrikbengtsson wrote:
Interesting to some extent however I think you will find that most potential medium format photographhers and current photographers couldn't care less about the ongoing DR hype on digital forums around the world.
This is true, but that the D800E stacks up with the 645D is big thing because this is the first time a 35mm dSLR could get close to that rarified air. For the medium format set, the question to be asking is how do they scale up that sensor to put into a MF body? Now wouldn't that make you drool?
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I was wondering if anyone else noticed their LO doing this. The last couple of days my DD's chin would quiver. She wasn't upset or hadn't been crying. I'd feel her legs, arms and stomach and they wouldn't be cold. Anyone have any ideas on what this is?
Quivering Chin
Posted 07/23/2009
Comments (4)
Posted 07/23/2009
Yeah, my daughter did this when she was younger; I think around 2 months old. Freaked me out. But I googled it and it turns out it's normal. It's just due to their immature nervous system.
Mom to the Wee Beastie (2008) and Beastie 2.0 (2012)
Posted 07/23/2009
It's just something baby does. It's totally normal.
Ali, peaceful parent� to Olive�breastfed and respected.
It is our choices that show what we really are, far more than our abilities. -Dumbledore
Posted 07/24/2009
Yes it's adorable isn't it? Don't worry unnecessarily this is completely normal all babies have them just enjoy while it lasts, short phase only :(


text:
- 65Promote
Shower Curtain
Slothby Claire Lordon
Customize your bathroom decor with unique shower curtains designed by artists around the world. Made from 100% polyester our designer shower curtains are printed in the USA and feature a 12 button-hole top for simple hanging. The easy care material allows for machine wash and dry maintenance. Curtain rod, shower curtain liner and hooks not included. Dimensions are 71in. by 74in.
Super cute!
Thanks Alexandra!
Thanks Nina's clicks!
Love this little guy! :)
Thanks Daisy!!
Hahaha, love it! There was a family of these in my university in Costa Rica (it was full of trees and green areas), they're so awesome to watch! (not if you're in a rush though, hehe)
Carolina - I'd love to see one in the wild. I've only seen them in zoos! How lucky!
So cute! I love sloths!
Thank you!
So cute!!!! ♥
Its so lovely! fantastic!
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