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News Details
Ecclestone back in Munich court for bribery trial
Formula One boss Bernie Ecclestone is back in a Munich court to answer charges of bribery in a case that could threaten his grip on the series. Two German investigators were to testify on Friday on the second day of the trial of the 83-year-old, who appeared calm as he entered the courtroom with his attorneys. The charges involve a $44 million payment to banker Gerhard Gribkowsky, who's serving an eight and a half year sentence for taking the money, allegedly to facilitate the sale of a Munich bank's stake in Formula One to a buyer of Ecclestone's liking. When the trial opened last week, Ecclestone told the court in a statement read by his lawyers he was blackmailed into the payment by...
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We received very positive feedback from last years trip to Jordan and are excited to run this trip again. The next trip will have an emphasis on single professionals, historic sights, the outdoors and getting into the water!
Note: This is a multi-city/chapter trip. The consolidated event link is here.
1.0 Itinerary
OCT 11 - Friday Evening:
Leave North America/Europe
OCT 12 - Saturday
Arrive in Amman. Visit Citadel. Meet & Greet Dinner.
Night in Amman
OCT 13 - Sunday:
We'll drive north to visit the Roman city of Jerash with its well preserved ruins. Towards the afternoon, we'll visit the tomb of Moses at Mt. Nebo.
Night in Dead Sea
OCT 14 - Monday
Today is an active day – first some easy canyoning in Waji Mujib, and then a visit to float in the Dead Sea. If time permits we'll have some tea and walk the cliff route at Dana Reserve for sunset and arrive Petra late in the evening.
Night in Petra/Dana
OCT 15 - Tuesday
The entire day is yours to explore Petra. We'll organize an introductory guide and you'll be free to explore the vast city at your own pace throughout the day. You might choose to climb to the Monastery or come early and return for Petra at Night.
Night in Petra
OCT 16 - Wednesday
We'll leave Petra late today so you may have a sleep-in or get some laundry done. After lunch we'll arrive at the amazing desert mountains of Wadi Rum. Here we'll begin with a two-hour jeep tour of the valley. After enjoying the sunset from a panorama we will spend the night in a Bedouin camp. Facilities will be basic but this will be an amazing night under the stars.
Night in Wadi Rum
OCT 17 - Thursday
In the morning there will be options for skydiving, ballooning or taking a morning hike. Mid-day we'll make the short journey down to the Red Sea port of Aqaba. There will be time for one afternoon dive or snorkel trip.
Night in Aqaba
OCT 18 - Friday (Aqaba)
Today we are on a boat for about 5 hours visiting two reefs. Divers, snorkeler's swimmers and non-swimmers are all welcome on the boat. Lunch is included. Tonight we will have a Farewell Party at before everyone flies home.
Night in Aqaba.
OCT 19 - Saturday (For Jordan)
Depending on flight times you may go to Amman and tour on your own or relax in Aqaba and go directly to the airport in the evening. We'll organize at least one/two day rooms for a late shower before getting on your flights.
OCT 19 - Saturday (For Israel)
Travel day to Jerusalem. This journey will be by public bus and will take most of the day. An escort will be available on both sides of the border but border crossing is on your own.
Night in Jerusalem
OCT 20 - Sunday (For Jordan)
Most flights leave from Jordan between 12:00am and 7:00am.
OCT 20 - Sunday (For Israel)
Half day tour of Old City in Jerusalem, including Western Wall and various Biblical sights. Afternoon is free to visit museums or other monuments. Evening bus to Tel Aviv.
Night in Tel Aviv
OCT 21 - Monday (For Israel)
Self Tour Tel Aviv.
Flight Home
* Syria Conflict
The Syrian conflict has to date not had any travel impact on Jordan. However DAYS 1/2/3 maybe modified in order or alternate destinations maybe selected. This would be in response to any change in the situation in Syria. The itinerary south of Amman (Petra, Wadi Rum and Aqaba) will not be impacted.
* India Extension
It is possible to fly a triangular route US/EU-JORDAN-INDIA-US/EU at a cost that would be much less than making two separate trips. Anyone that has business or family in India that would like to visit India for a few days after Jordan should contact us on how to get the best fares on these flights.
2.0 Costs
2.1 Jordan Trip:
• Accommodation on a shared basis
• All 3-4 Star hotels plus one night in Bedouin tent
• All transportation
• Most breakfasts
• Dedicated vehicle and driver
• Dedicated activity, meal & assistance Enrouta representative
• Jerash entry and tour
• Petra entry, full lunch and tour
• Canyon Hike
• Dead Sea Float
• Mt. Nebo Visit
• Wadi Rum Jeep Tour
• Wadi Rum Bedouin Dinner
• Aqaba Lunch
• Day tour on Red Sea boat for snorkeling, swimming and relaxing.
• Dives (offered at steeply discounted rate)
• Sky Diving
• Hot Air Balloon
• Cooking Class
• Most Meals
• Last day optional Amman Tour
2.2 Israel Extension:
225GBP Early Booking Rate (Before July 15th)
• Accommodation on a shared basis
• All transportation except last taxi from Tel Aviv to airport (Approximately $40 for 3 People). Last taxi should be paid by cash. Please note portions of this trip will be on public bus.
• Guided tour of Jerusalem
• Arrival representative after border control
Any confirmation requires a 250GBP deposit. To book a spot please email [masked].
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subset: commoncrawl


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Born 3-14-1938 -- Died 3-22-2008
Kenneth Max Pingleton, 70, of Koshkonong, Mo., died March 22, 2008, at his home. He was born March 14, 1938, in Alton, Mo., the son of George and Thelma Pingleton. Max was married to Mary Christine Holman on Nov. 26, 1958.
He was a member of the United Baptist Church. He retired in 1991 from J.I. Case Company after more than 30 years of service. He continued working with farm machinery during summers with the Pro-Harvest Support Team.
Survivors include: his wife, Mary Christine of the home; one daughter, Kristy Fluhr and husband, Chris of Dardenne Prairie, Mo.; one son, Greg Pingleton and wife, Becky of Villa Ridge, Mo.; two grandsons, Michael Pingleton and Tristan Fluhr; and twin granddaughters, Megan and Marissa Fluhr; his siblings, Georgia Wynn and husband, Larry, Don Pingleton and wife, Minnie, and Freda Weber and husband, George; his sisters-in-law, Alice Barton and husband Howard, and Mittie Pingleton; his brother-in-law, Jack Holman; and numerous other nieces, nephews, relatives and friends.
He was preceded in death by: his parents and one brother, Carl Pingleton.
Services were held March 26 at the Clary Chapel in Alton, ?Mo., with interment following in the Huddleston Cemetery. Arrangements were under the direction of the Clary Funeral Home of Alton, Mo.
In lieu of flowers, the family has requested donations be made to the American Cancer Society Hope Lodge or the Juvenile Diabetes Research Foundation.


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Do you enjoy your property rights?
To the Editor:
To residents of Greene County, Indiana; reject government control of private property.
The Greene County Economic Development Corporation, contracted by elected officials, supported by tax dollars, is seeking to impose land use planning and controls/zoning in Greene County, and is now conducting a planning study which, if adopted, will become the legal foundation for ordinances that can take away your property rights forever.
Citizens for Property Rights, a non-profit group formed in response to this threat, invites you to join us. We are an issue-only interest group not affiliated with any political party or other organization and welcome all county citizens as members. We believe in the full, free use, and enjoyment of our property, and that such use should be free from interference, threat, or control from anyone especially, control in any form by the government. We reject all forms of land use controls as a government seizure of private property rights.
Our objective is to provide a unified voice of opposition, recommend candidates for election or defeat, and become a voting block too large to ignore. Only by uniting in opposition, working through the political process and by voting in great numbers for the right candidates, can we stop this assault on our freedoms. Join us, and for once, let the people govern, not misinformed or unresponsive elected officials who think they know better than the voters.
To our retired citizens who have lived your whole life free of government control; help save that freedom for your children and grandchildren. Bring your time, energy, and wisdom to our cause. Volunteers are needed from each city to organize new members. Also needed; legal services/advice, Web services, phone volunteers, and polling place volunteers. Remember, we should not be so busy enjoying our freedoms that we can't take a small amount of time to defend them, or one day when we look, they will be gone forever.
Please join us.
Donations may be made payable to: Otis J. Russell, Chairman, CFPR, R.R. 1 Box 140, Switz City, Ind., 47465.
Otis J. Russell
Switz City
Glenn family
says thank you
To the Editor:
The family of Cecil J. Glenn would like to say thank you to all who showed their love and support with their prayers, phone calls, food, flowers, cards, visits, and momentos we received in memory of Red, my husband, our dad, grandpa, brother, and uncle.
Words can never express the gratitude and love we feel as a result of your many acts of kindness and sympathy extended to our family during this difficult time.
A special thank you goes out to Jim Meng and the Anderson Poindexter Funeral Home, Jack Shelton, Rev. Goodman, the Masonic Lodge 560, Bob and Elizabeth White and the Lincoln Christian Church, Janice Slover, Dr. McDougal, Travis Carpenter and the staff of Greene County General Hospital, Carol Butler and the staff of the Linton Laundry Center, the pall bearers, and all who took time to show us how much you cared by sharing your time with us.
May God's love touch you and richly bless each one of you.
Adah Glenn
Lena Brinson
Melody Souders
Judy Mullis


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Feb 05, 2016 5:20pm
A collection of stories worth knowing about that you may have missed.
Feb 05, 2016 11:00am
When your client wants consumer-grade gear to save money and you insist the business needs a more robust solution, there's an alternative that can satisfy you both.
Feb 05, 2016 11:00am
Don't overlook the chance to upsell profitable hardware such as wireless headsets when you deliver those shiny new PCs.
Feb 04, 2016 12:00pm
The new projectors offer up to 8,000 lumens of color and white light brightness, 4K Enhancement resolution, and motorized lenses.
Feb 04, 2016 12:00pm
The company offers Enterprise LTSB version of Windows 10 on its rugged tablet.
Feb 04, 2016 12:00pm
The fire- and waterproof hybrid BDR 515 solution delivers disaster recovery and protection during Internet outages with near-zero recovery point and time objectives.
Feb 04, 2016 12:00pm
The new ATS PDU series provides 8.6 to 17.3 kW of redundant, reliable power to single- or dual-corded rack loads in a compact form factor, saving in-rack space and reducing hardware costs.
Feb 02, 2016 4:46pm
The new release adds simplified installation and instant recovery capabilities, plus enhanced support for Linux devices.
Feb 01, 2016 11:44am
Our weekly preview of this week's top stories in the SMB channel.
Jan 29, 2016 5:29pm
The new SharePoint intranet portal centralizes access to important business information and apps in Office 365.


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Change Location
ACE Fit Share
Fit Life Articles
You don't have time to be out of commission with a nasty head cold or the aches and fever of the flu. Check out these six ways you can boost your immune system and more effectively fight off the nasty viruses that seem to be lurking everywhere. And if you do happen to get...
Knowing how to measure and use your heart rate is essential if you want to get the best results from your exercise program. Here are some tips for using heart rate to identify the most appropriate exercise intensity for your needs and goals.
If you can't decide if you should follow a low-carb or a high-carb diet, why not just combine the two diets in an effort to address all of your sports-performance and weight-loss concerns? Known as carb cycling, proponents claim this dietary approach offers a wide range of...


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Logitech M570 Wireless Trackball
This is came out in .
This is a improvement over Logitech's previous Logitech Trackman Wheel.
- A scroll wheel! Excellent.
- 2 extra programable buttons. (used for example for next/previous page history for browser) This is extremely convenient.
- Laser tracking tech. (No need to clean the ball anymore.)
- Wireless.
- Thumbnail sized USB receiver.
Overall, it got positive reviews. However, compared to the classic Logitech Trackman Wheel (red ball) , the ball is a bit smaller and is a little more stiff to spin. This is also twice as expensive.
Logitech Wireless Trackball M570 Ball Size
The ball diameter is 34 mm.
For replacement, you can buy at amazon
If you want a WIRELESS trackball, you don't have much alternatives.
There's Elecom Wireless Trackball Mouse. See Best Trackballs
There's Kensington Orbit Wireless Trackball, but it isn't as good.
See: Best Trackballs Comparison.


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Good Techniques: Radish, Asparagus and Feta Salad with Toasted Cumin Vinaigrette
Private Chef Julia Phillips is now helping you practice good techniques in the kitchen! This week …
Cooking with Lauren K: Hot Italian Hummus Dip
Lauren K finishes Hummus Month with a recipe for a Hot Italian Hummus Dip.
National Pretzel Day
Dawn and KC O'Day from WALY 103.9 FM make Salted Beer Pretzel Crescents in honor of National …
Jessie Pierce's Balsamic Salad Dressing
Chef Anne Quinn Corr, author of the cookbook Seasons of Central Pennsylvania and the iCookbook …
Sip & Sauté by DeGennaro: Pe Pa Soup
Join the fun at Sip and Sauté by DeGennaro; a unique cooking demo experience! Chef Janet shares a …
Cooking with Lauren K: Kalamata Olive Hummus
Lauren K continues Hummus Month theme with recipes for a Kalamata Olive Hummus and a Turkey and …
Seared Pepper Trout with Creamed Ramps
Mandisa Horn from Horn O Plenty in Bedford shares her recipe for Seared Pepper Trout with Creamed …
Passover Jerk Chicken
Don Clippinger, author of the cookbook "Real Jewish Men Cook Kosher", shares a recipe for Passover …
What's Cookin' in the Easy Bake? Sponge Cake!
Dawn and KC make Sponge Cake in the Easy Bake!
Cooking with Lauren K: Hummus Month
Lauren K continues Hummus Month theme with recipes for a Roasted Red Pepper Hummus and a Turkey and…


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Active Sailing-Touring Trips for the discerning traveller, all levels of sailing. Take part sailing PWYLL or just relax. Trips designed to suit your interests. Live aboard sailing charters June -September, 2016. RATHERBESAILING ORG
Let us entertain you and show you around the Greek Islands on this superior category classic Beneteau yacht, three double ensuite guests cabins plus separate crew quarters. Italian-Greek Gourmet Chef onboard. CONTACT TODAY FOR ENQUIRIES AND BOOKINGS!
We address people seeking activities that combine getting to know the island's nature, sports and traditional tastes and flavors. We want you to experience a different side of Rhodes, the one we local explorers enjoy.
SMV TRICIA, built in 1938 is your unique holiday accomodation on a tiny Greek Island. Tricia is moored in Lakki Marina, Leros; holiday includes two day sails on S/Y Watson, a 12m dufour & exclusive use of Tricia for 14 days from August 3-16.
Angelika is amphitheatrical builded surrounded by a wonderful garden full of colours.Angelika is the most traditional hotel in leros
Grikos Hotel is a unique, traditional place and a smart choice for your ac-commodation, which combines luxury and tradition on the island of "Revelation", Patmos. Grikos Hotel is situated in the most magnificent bay of Patmos, Grikos.
This retreat is tailored for individuals wanting to connect with their values and strengths, develop more meaning and purpose in life. The retreat includes 10 days single accommodation at Aegialis Spa Resort, all nutritious and delicious meals, daily
Traditional hotel IANTHE is located in VESSA, one of the Medieval villages of Chios, in the centre of island, in distance 19 km of city Chios. The village took his name probably from the Homirian name [bissa]=[valey] .
Just in front of the sea!! Very nice self catering rooms or apartments for relaxing holidays! We have a lot of repeat guests! Heaven on earth!! The quiet simplicity of rooms albeit without any compromise whatsoever as to modern amenities, are what
Welcome to Villa Rose On the most beautiful island of the Cyclades, Santorini, you can find Villa Rose. Villa Rose is a small friendly family run business. It is situated on the lower road in Fira town, Santorini's capital, and is literally 7 minu
Select your destination in Kos Greece. Browse thousands of listings for accommodations, adventures, tours and travel services.


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Mystic Blue Signs opened our shop on Magazine Street in 1996, but we have been specializing in hand lettering and illustration since 1973.
New Orleans has such inspiring architecture and history that it's a natural location for a hand-painted sign shop. We use traditional methods and materials and we draw everything by hand, from logos to lettering to illustration. We hand-cut, hand-carve, hand-paint. We use wood, metal, special sign paint and sign painters' quills, flats and fitches. We use real 23 karat gold leaf sheets on signs and glass transom numbers. We even paint scenes and signs on the sides of buildings. And we ship signs all over the world.
For the last eight years, Mystic Blue has hosted regular art shows in our gallery, featuring local artists. We sell prints, paintings, posters, signs, stained-glass, jewelry and objets d'art made by our artists. Studio/Gallery hours are Tues thru Fri 10:30am-5pm and Sat 10:30am-3pm.
We were mentioned in Seth Kugel's informative and kind New York Times Frugal Traveler's blog on New Orleans. You can view it at this link: NYTimes.com Blog
Hand-writing demo by Yvette at WWL Channel 4 for National Hand-Writing Day.
Visit the NOLAA website: www.neworleanscalligraphy.org
Special Projects We also do a considerable amount of Documents, Marriage Certificates, Wedding Invitations, Murals, Portraits and Illustrations. Here are some samples of our work. Call us at (504)525-4691 if you would like us to help you with that special project!
Center News: § Happy Spring! §
Font Club will meet Saturday, March 19th at 3pm. This meeting will be a work session. Font Club is a free informal group that meets on the 3rd Saturday of every month to work on typeface design. Call Vince or Yvette at (504) 525-4691 for more information. www.fontlab.com § forum.fontlab.com
Visit www.aiganeworleans.org for graphic design info, events, and meetings in New Orleans.
The New Orleans Lettering Arts Association (NOLAA) will meet March 12th at 9:30am at the East Bank Regional Library (4747 West Napoleon Ave., Metairie). Maria Helena Hoksch will share tips to improve your skill with the broad edge nib. This class will be beneficial to beginners and advance calligraphers.
NOLAA meets on the 2nd Saturday of the month. NOLAA is a non-profit organization whose monthly meetings are mini-workshops in a variety of calligraphy techniques, well worth the $25 per year membership fee. For more information visit www.neworleanscalligraphy.org
We are proud to have an exhibit in the gallery of Claire's photographs capturing her unique perspectives of life.
Enter Code: MYSTIC10 for 10%off


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For the most upside, Cramer's looking to State Street (STT Quote), another Action Alerts Plus name. State Street is a custodial bank, which holds money for other banks and has little exposure to the economy as a whole, he said. Second on the list was BB&T (BBT Quote), a bank that raised capital even when it didn't need to, and is now ready for serious acquisitions of smaller, failed banks.
Isn't anyone considering that BBT could be a takeover target?
Thanks! First post I've read that explains in language I can understand why we lost 2/3's of our dividend and took TARP money when the then CEO - JA - said we didn't need it. So we can buy failed banks.


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A number of good points made in the open letter to Parsons, but here is my take.
Parsons must make a ruling that speaks to the future. He cannot award "fantasy" money, as he called it, to PIP.
IMO, he must only award reliance damages. This is simple and speaks to the future. It tells companies if you want protection above and beyond reliance damages in a situation like this, you have to spell out the what if`s in detail in writing. Clear and simple.
Parsons made a bad finding of fact; that the parties would have reached an agreement if not for bad faith. That's why he has to muddle a damages award. The SC pointed this out, indirectly. If it's difficult to fashion a remedy, i.e. if terms of the incomplete contract need to be fabricated by the court, then the premise that there was injury that can be compensated is faulty. PIP can never get the benefit of the bargain because the terms were never defined sufficiently to determine with any certainty what that benefit would be. The economic terms were developed which represent the upside but there was nothing tangible in the LATS that represents the downside. How much would it have cost PIP to bring the drug to market, and was there reasonable certainty that it would get through development? In 2006 no human trials had been completed.
Well, in this damages reward I hope Parsons factors in the risk SIGA was taking at the time they walked away. Another round of testing had to be done.
I still don`t get why PIP is so deserving. The theory they deserve half does not seem fair for the risk they took at the time. I have no doubt PIP would have walked away if the chimps died, SIGA would be bankrupt and there would be no lawsuit to force PIP to buy the remnants of a worthless company.
You are wrong about Parsons findings, as clearly stated by Delaware Supreme Court on page 37 of its decision:
"In this case, the Vice Chancellor made two key factual findings, supported by the record: (1) 'the parties memorialized the basic terms of a transaction in . . .the LATS, and expressly agreed in the Bridge Loan and Merger Agreements that they would negotiate in good faith a final transaction in accordance with those terms' and (2) 'but for SIGA's bad faith negotiations, the parties would have
consummated a license agreement.' The Vice Chancellor's factual conclusions support a finding that SIGA and PharmAthene entered into a Type II preliminary agreement and that neither party could in good faith propose terms inconsistent with that agreement."
How is a finding of fact addressed by Delaware Supreme Court as being "supported by the record" wrong?
Delaware Supreme Court is clearly indicating they lost the benefit of the bargain and agree with Parsons in that regard.
If he does that, every single agreement that includes the legal term "in good faith" is null and void. Either party can screw the other without recourse or significant financial penalty. Without penalty, the any such commitment is meaningless as either party can do the math at some future date and determine that hassle of litigation, which they will win, is worth the trouble.
"Clear and simple"
Nothing, in this world, is clear and simple. In fact most of it is blather and bamboozel.
Why, some may prevail in saying that if the glove don't fit, you gotta acquit. Other may say that's nonsense. Some may prevail in a matter in saying that it all depends upon what the definition of "is" is. Or that a BJ isn't sex. Other may say that's nonsense.
My take? Well, at this point, what difference does it make?
a beaver jamb(BJ) is a folk dance that can possibly lead to sex if done while standing
You can't read a lick can you? The Supremes directed Parsons to award expectancy damages, and that is in fact what he will do.
"and that is in fact what he will do."
....or, not. He may do something that the Supremes will examine and overturn. Like he did the first time.
The other issue is that Parsons will never read it, AND the author bases too much of his opinion on "what if". Again, had PIP negotiated in bad faith, SIGA would have been able to drag them into court and hold them accountible. The case, at this point, is NOT about "well, PIP would have done it too" and "But, they never paid anything".....and IS about the fact that SIGA is liable for not negotiating in GOOD FAITH as they had promised, and what the ACTUAL and APPROPRIATE damages should be for them not doing so. We all know that PIP is full of #$%$-buckets and losers that would have walked had the results been bad, but they weren't and they're not the ones being sued.
Is that Pip did it too but Siga got caught, or they both did it but Parsons was bought? You may think Rose stinks, but this Parsons is about as bad as they get.
I'm with you on that Drod.


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Retractions are on the rise. But reams of flawed research papers persist in the scientific literature. Is it time to change the way papers are published?
Environmental Visionary Dies
September 26, 2011|
Wangari Maathai, a human rights advocate and Nobel Peace Prize Laureate, started a movement to plant more than 30 million trees and generate nearly 1 million jobs.


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Join the 'Oophorectomy' group to help and get support from people like you.
Oophorectomy Support Group
Our support group for Oophorectomy has 12 questions and 14 members. Updated 23 Jun 2015.
Latest News
Early Ovary Removal May Be Tied to Lapses in Memory, Thinking
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Previous Venue Next Venue Venue Description
1. Samui Thai Kitchen 3616 SE Hawthorne Blvd, Portland, OR 97214
Samui is an island in southern Thailand, the region of the country that shares a border with Malaysia. The proximity of the two countries has resulted in a large crossover of cultural particularities, and cooking has certainly been influenced. The people at Samui Thai Kitchen decided to bring their favorite food from home all the way to Portland, turning out American favorites like pad Thai and drunken noodles alongside more authentic dishes like Massaman curry, green curry with beef filet, and soup nuer.


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Day 1 | Day 2 | Download Brochure | Download Exploring Epigenetic Targets Brochure
Histone methyltransferases (HMTs) and demethylases (HDMs) have rapidly emerged within the suite of epigenetic modifiers as new and promising classes of therapeutic targets. Recent genetic discoveries of HMT and HDM anomalies in various cancer types provide unique validation for selective and tumor-specific targeting of these enzymes. Clinical intervention is becoming increasingly feasible, but deciphering their role in complex disease, developing robust screening and hit-finding approaches for inhibitors, and addressing efficacy and safety remain challenging. Join pharmaceutical, biotech and academic researchers for practical solutions to challenges, while exploring the expanding arena of HMT and HDM therapeutics.
1:30 pm Chairperson's Remarks
Abdellah Allali-Hassani, Ph.D., Team Leader, Enzymatic Assays, Structural Genomics Consortium, University of Toronto
1:40 Screening Methods for Identification of Selective Inhibitors of Histone Methyltransferases
Epigenetic regulations of gene expression, including mechanisms dependent on histone methylation, have been implicated in a variety of diseases including cancer. Increasing interest in identifying inhibitors of histone methyltransferases (HMTs) as targets for a new generation of therapeutics, necessitates developing optimized screening methods for these enzymes. Here, we report assay development and screening methods for more than 16 HMTs and their application in discovery of selective inhibitors.
2:10 Development of a Novel Demethylase Assay and High-Throughput Screening for Demethylase Inhibitors
Ji-Hu Zhang, Ph.D., Senior Research Investigator, Center for Proteomic Chemistry, Lead Finding Platform, Novartis Institute for Biomedical Research, Inc.
Histone methylation misregulation has been found to be associated with various disorders. Assays for detecting methylation state changes are very useful tools for studying the function of these epigenetic marks. In this presentation, a sensitive homogeneous assay for demethylase activity at the H3K4 site has been developed in a TR-FRET assay format. The assay was validated for lysine-specific demethylase (LSD1) and demonstrated to be suitable for high-throughput screening.
2:40 Histone Methyltransferase Inhibitor Selectivity Profiling: Effects of Substrate Choice for in vitro Assays and Comparison to the Results of Cell-Based Assays of Histone Methylation States
Konrad T. Howitz, Ph.D., Director, Epigenetics, Reaction Biology Corporation
In vivo, histone methyltransferases (HMTs) target specific histone lysine or arginine residues at particular locations in chromatin. In vitro assays for HMT inhibitor profiling can be performed with peptides, histone proteins or nucleosomes. To better understand the factors that may make in vitro HMT assays predictive of inhibitor effects in vivo, we are profiling selected compounds by in vitro assays with multiple substrates and by cell-based assays of histone methylation.
3:10 Refreshment Break in the Exhibit Hall with Poster Viewing
3:45 Progress Towards Chemical Probes for Epigenetics
Dafydd Owen, Ph.D., Associate Research Fellow, Pfizer, Inc.
Pfizer is a partner in a pre-competitive research collaboration with the Structural Genomics Consortium. This research is focused on the discovery of high-quality chemical probes for emerging targets in epigenetics. These probes will be disclosed publicly and will have no restriction on use. The intention is to provide tools to help understand the potential role, efficacy and safety of targets including those from HMT and HDM classes. Pfizer has programs in both of these areas and will provide an update on our progress.
4:15 High Throughput Methods to Study Methyltransferases and SAM-Binding Site Inhibitors
Levi Blazer, Ph.D., Scientist, Molecular Screening, Cayman Chemical
Methyltransferases are attractive drug targets; however assay methodologies for these enzymes are laborious when compared to most high-throughput assays. Cayman Chemical has developed a small molecule fluorescent probe that simplifies high-through-put screening for methyltransferase inhibitors.
4:30 The Determination of Epigenetic Target Specificity and Identification of Epigenetics-related in vivo Adverse Drug ReactionsManilduth Ramnath, Ph.D., Project Manager, Custom Services & Innovation, CEREP FranceScreening of 1000 compounds from the BioPrint® database for activity against "writers", "erasers" and "readers" of the epigenetic code was performed. Resulting in the identification of epigenetic altering compounds as well as the establishment of relationships between the inhibition of specific epigenetic target and known adverse drug reactions associated with these compounds.
4:45 Toward Chemical Probes of Histone Methyltransferases Altered in Cancer
Drew Adams, Ph.D., Research Scientist, Chemical Biology Program, The Broad Institute
Various histone methyltransferases (HMTs) have recently been implicated in cancer and other disease by unbiased genomics studies. We have initiated probe development efforts against several HMTs that appear to be hyperactive in one or more tumor types. Multiple approaches, including the development of biased chemical libraries and high-throughput screening of compounds synthesized at the Broad Institute, have been employed to identify active compounds.
5:15 Harnessing Structure-Based Drug Design to Accelerate Candidate Drug Identification
Philip Fallon, Ph.D., Senior Medicinal Chemist, Domainex, Ltd.
A good supply of PKMT protein is necessary to develop biochemical assays and obtain crystal structures. The expression of domains of interest can be sufficient to enable these activities. Structural biology enables very efficient "hitfinding" by means of our virtual screening approach. Also, utilization of a range of virtual screening strategies increases the likelihood of identifying hits. Finally, the discovery of a new class of small-molecule inhibitors of G9a and GLP will be discussed.
5:45 End of Day
The exhibit hall was sold out in 2015, so please contact us early to reserve your place. To customize your sponsorship or exhibit package for 2016, contact:
Jon Stroup
Sr. Business Development Manager
Next-Generation Histone Deacetylase Inhibitors
Strategies for Tackling Rare Genetic Diseases
Understanding CRISPR: Mechanisms and Applications
Autoimmunity – Small Molecule Approaches
NK Cell-Based Cancer Immunotherapy
Targeting Histone Methyltransferases and Demethylases
Targeting the Ubiquitin Proteasome System
Targeting the Microbiome– Part 1
GPCR-Based Drug Discovery - Part 1
Advances in Gene Editing and Gene Silencing – Part 1
Gene Therapy Breakthroughs
Antibodies Against Membrane Protein Targets – Part 1
Targeting Cardio-Metabolic Diseases
Targeting Ocular Disorders
Targeting Epigenetic Readers and Chromatin Remodelers
Kinase Inhibitor Discovery
Targeting the Microbiome– Part 2
GPCR-Based Drug Discovery - Part 2
Advances in Gene Editing and Gene Silencing – Part 2
Decoding Cancer Genomics
Antibodies Against Membrane Protein Targets – Part 2
Metabolomics in Drug Discovery
TRAINING SEMINAR: Data Visualization


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The Art of Imagination - Duos for flute & harp by Bax, Doppler, Hilse, Andy Scott & Zamara / Verena Beatrix Schulte, flute; Hanna Rabe, harp
1 CD / TYXart / 2015-11-13Works: Bruno Hilse: Suite, for flute & harp, Op. 6; Arnold Bax: Sonata for flute & harp; Antonio Zamara: Casilda Fantasie, for flute & piano; Andy Scott: Sonata for flute & harp
Ensemble: Queens Duo
The debut CD by the Queens Duo dedicates itself to human fantasy and imagination and the four tracks in the collection enchantingly range from Romantic...continue...
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The Bad Tempered Flute: Music of Andy Scott / Southworth, Findon, Scott, Carey et al.
1 CD / Nimbus Records / 2011-09-01Works: Andy Scott: Three Letter Word, for flute & piano; Nemesis, for saxophone & vibraphone; And Everything Is Still, for flute & piano; My Mountain Top, for solo flute; Sonata for flute & piano; Sonata fo...
Performers: Carey, Tim; Edmund-Davies, Paul; Findon, Andrew; Lawson, Peter; Ogden, Craig [Guitar]; Scott, Lauren [Harp]; Southworth, Clare
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The feeling you get when your best homie seems to have a new best buddy... made up of bro + jealous.
They've known each other for 12 years, but as of late, John spends so much time with his new neighbor that Kyle starts to feel brealous. In fact, he just texted John "I'm so brealous, this bromance is over!"
by ricci-s September 12, 2010


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Welcome to the Utah County Attorney's Office
With twenty-nine attorneys and five detectives, we are the largest law firm in Utah County and have one of the larger detective bureaus. Together with our support staff of more than thirty legal assistants, paralegals and law clerks, we prosecute thousands of adult and juvenile felonies and misdemeanors every year. We also provide legal advice and representation to Utah County Government and investigate a small number of complex crimes and homicides.
Latest News
On Thursday, February 11, 2016, following a three day trial, an eight person jury from Utah County found Robert Alonzo Peraza, 29, guilty of four first degree felonies for Sodomy on a Child.
On October 9, 2015, Joshua Jay Harding pleaded no contest to Child Abuse, a 3rd Degree Felony, and Negligent Homicide, a Class A Misdemeanor.
On April 20, 2015, Ms. Hunstman was sentenced to six life sentences, three consecutive and three concurrent, at the Utah State Prison. The first parole hearing date is scheduled for April 2064, at which time she will be 89 years old.
Newsroom >>


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804 Miles
1294 Km
12 hours 11 mins
659 Miles
1060 Km
1 hours 54 mins
37.22 Gallons
Fuel Needs
0.91 Pounds CO2 fp per miles
Distance from Huntington, WV to Boston, MA is 804Miles or 1294 Km. You can get this distance about 12 hours 11 mins. If you want to planning travel with plane, you can get this distance about 1 hours 54 mins .
A car with an average MPG will needs 37.22 gallons of gas to get the route between these points.
The estimated cost of gas to get between Huntington, WV and Boston, MA is $84.49.
During the route, an average car will release 729.21 pounds of CO2 to the atmosphere. Your carbon footprint is 0.91 pounds of CO2 per mile.
* Average US MPG used for calculations is 21.6 MPG.
* Average US gas price used for calculation is 2.27 per gallon.
* Coordinates of Huntington, WV is 38.419237, -82.4452319 and coordinates of Boston, MA is 42.359824, -71.0598125
All Rights Reserved. © 2010 - 2016 About Feedback


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who IS that chick>!?!?!?!?!?!? LOVE her!!!
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lucy man nice girl mmmmmmm
lucky bitch!..


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The season has come to an end, but before we let these guys quietly sneak out the back door, we feel that it's our civic duty to highlight their worst moments. Because that's what bloggers do best. If you caught every episode of "Real World: New Orleans," then you know we had tons of material to go through. Here's what made the list:
Guilty Party: Eric
Everyone knew–including Eric–that it was only a matter of time before he erupted on his inconsiderate roommate, Ryan. After c—blocking a girl, losing the car (and blaming it on other people) and then stumbling home at 2am, Eric jumped out of bed (in just his skivvies!) and threatened to kick Ryan's booty.
Guilty Party: Ryan
Ah yes, the infamous wiping of the bum with Preston's cigarettes. The best part of this was the fact that Ryan kept denying that he did it (dude, it's on camera!). Can't wait until they get to the bottom (ha!) of it at the Reunion Special (airs next Wednesday at 10/9c)!
Guilty Party: Preston
The ongoing roommate feud took an irreversible turn when Preston stole Ryan's Sonicare toothbrush, scrubbed the toilet bowl with it and then urinated on the bristles. It was really challenging to pick a side after that. At least Presto owned up to his wrongdoing!
Guilty Party: McKenzie
Remember when that McSleazy picked up McKenzie–who goes by "Mary" when she's wasted–at a bar, got her trashed and then tried to take her home? Thankfully, McKenzie had enough sense to jump in a cab and leave, but this was definitely one of Mary's sketchier moments.
Guilty Party: Jemmye
It's hard to remember a time when the Mississippi native wasn't downing shots on Bourbon Street, but the night when she got completely obliterated and collapsed in the shower was scary. 'Course, Knight was there to make sure nothing too bad happened.
Guilty Party: Ashlee
This incident never made it to an episode, but we dug around and found it on the Real World Dailies site (if you're looking for extra hilarious footage, go check it out). Somehow, Ash got completely 'faced to the point where four people had to lift her into bed.
Guilty Party: Sahar
More embarrassing than forgetting the words to her own song was when she let Pablo, her boyfriend from Michigan, blow into town and treat her like crap. On the night of her big performance, he was a drunk, unsupportive douchebag that–somehow–still managed to get the girl!
Guilty Party: Knight
On last week's episode, Knight took his I-don't-care-about-you attitude up a few notches when he told Jemmye "you're only good for one thing"–while she was lying in bed next to him! His insensitive comments drove her to a breaking point, and she punched the kid in the face!
+ What was your favorite moment from the season? Did we miss anything? Sound off in the comments!


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So, I just love to drive around Phoenix in my Ford SUV looking for a black guy to go back to my house so he can fuck me with his huge hard thick black cock until he cums in me with it! Love Black Men & Their Thick Big Black Cocks! mmmm


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Leave Your Favorite '90s Cartoons In The '90s, Where They Belong
- By Adam Bellotto
- @Eat_Sleep_TV
- September 7, 2015
Does the world need (or even want) a crossover movie involving all your favorite Nickelodeon cartoons from the 90s? Doesn't matter, we're getting one anyway....
'Fun Size' Trailer is Halloween Family Fun with a Humping Chicken
- By Scott Beggs
- @scottmbeggs
- June 29, 2012
Josh Schwartz is taking the success he found on TV with shows like The OC and Chuck and translating that into a directorial debut fit for families. It also manages a slutty kitty and a humping chicken. You know, for kids. Fun Size stars Victoria Justice as a teen on...
'Ninja Turtles' Gets a Wonderfully Generic Title
- By Scott Beggs
- @scottmbeggs
- March 26, 2012
Of all the critiques lobbed at the John Carter's marketing problems, one of the more devastating was that the name was boring and meaningless. Where do you go after that? How do you build advertising when your name is terrible (or worse: dull)? So, it's in that spirit that, according...
Channel Guide: Taking a Nostalgic Seat on Nick's Big Orange 90s Couch
- By Merrill Barr
- July 30, 2011
Nickelodeon… It's a name that has become synonymous with children's programming. From the wacky to the heartfelt, what started as a subsidiary of MTV has slowly become a beast of its own. A beast that was spawned in that now distant memory of a decade known as the nineties. From 1990-1999, Nickelodeon OWNED...
Is Shyamalan Out of His "Element" for The Last Airbender?
- By Ashley Demma
- June 10, 2008
Damn it feels good to be an Avatar! (I'm about ten seconds away from grabbing a blue Sharpie and drawing an arrow on my head.)...
Covert Penguins Go Back to Madagascar
- By Joe Ngo
- December 12, 2007
You might remember these lovable guys as the crazy CIA penguins -- now they may be getting their own TV show....


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Welcome to the Foxridge Community Foxridge is a beautiful and well-established community located in the southern part of the Denver metro area, Major streets -- Quebec on the East, Holly on the West, County Line on the South and Dry Creek on the North. In the City of Centennial, Arapahoe County. This web site is managed by the Foxridge Improvement Association Board of Directors. Membership in the FIA is available to all 934 residences.
The Latest News from Your Foxridge Board
The benefits of your voluntary membership include:
-Annual Easter Egg Hunt -Annual Community Garage Sale
-Dumpster Day -Neighborhood Picnic at the Park
-Horse Drawn Holiday Carriage Rides -Covenant Advisor
-Neighborhood Teen Services Listing -Neighborhood Newsletter
-Representation at City of Centennial Meetings and Management of GID Funds


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[quote:Phasesphere:MV83NDYxNDZfMTE0NDY1NDhfNDQ4MDNBMEI=] [quote:Princess Bride] This is just weird. We were at Walmart yesterday when they had an emergency drill or test. It about drove me nuts. It was a constant announcement over the loud peakers telling us to leave our stuff and exit the store in calm orderly fashion. Illinois, also. [/quote] Wonder what happens when you go outside and its not a drill???? [/quote]
Original Message
I picked up this on the www.apfn.net
there is some truth in this report as I live in Oregon. There was some really bizarre weather yesterday. Very strange snow, sleet, hail and rain during the days.
I wouldn't be surprised since the government calls Oregon the "Little Beruit"
Get ready folks in the northwest!!!
Portland 3/11/09 exercises preparing for martial law?
This evening I received the message below from W. Leon Smith, my publisher at The Lone Star Iconoclast. While it is impossible -- without further information -- to evaluate this, it is nevertheless of concern to me. It should be of particular concern to those readers living in the Portland/Seattle area.
As many of you know, I've rated Portland as the tertiary US false flag target, behind Houston and Chicago. For more, search my article "False Flag Prospects, 2008."
A couple of other things come to mind... One is that 3/11, the date identified below as the start day for the exercises, is the fifth anniversary of the Madrid bombings -- and we all know how much the NWO kooks like repeat dates. I just published an article about date coding, easily found with the search phrase "USA 666 WMD"
The other is that NASA is sending up a shuttle on 3/11. The simulated nuke that Ghost Troop documented just south of Houston on 7/28/05 came after the 7/26/05 launch of Space Shuttle Discovery, which was the first shuttle flight after the Columbia explosion three years earlier. The interview transcript should be listening for those who suspect that NASA is a military operation at heart, and that the government can and will do what it wants as the media shuts the matter up: [
link to Do_not_use_this.com
Any feedback related to my thoughts above or Mr. Smith's report and questions below would be most welcome! Thanks, Captain May
--- On Mon, 3/9/09, Iconoclast wrote:
From: Iconoclast
Subject: re: question regarding execises
To: "Captain May"
Date: Monday, March 9, 2009, 6:24 PM
Capt. May,
I have just been told by an anonymous source that U.S. Navy Exercises (NW TRAINING COMPLEX) are being planned to begin on March 11 in the Portland area that will include the states of Washington, California, Idaho, Nevada, Alaska, and other areas, as well, and that these are unpublicized exercises. Also, I was told that the Navy has refused to follow through on considering normal environmental impacts of the weapon tests that are planned.
I was told that contracts have been issued for bottled water, prisons have been established on boxcars, and that there are a lot of Blackwater-type mercenaries in those areas.
Also, I was informed that the weaponry fired will include DU rounds, red, white and yellow phosphorus, CHFF particulates, RDX, and HDX, and MOAS 1, 2 and 3 (I don't know what these last ones are).
The person calling me was female, and claimed to be a teacher, Girl Scout leader, and a wildlife naturalist. She said that as we were speaking it was snowing at her location in Portland and that the consistency of the snow was not normal ("very heavy"). She said that as a longtime resident there she knows a lot about how snow falls and what it looks like and this is not normal. She said, "I know snow." She was concerned about HAARP weather weaponry being used there. She said that she didn't know what they were, but several people have commented about seeing chemtrails.
She said that there are a lot of people there who are worried, but there is no organizing entity for them to share their concerns. Anyone addressing authorities is usually ridiculed.
She said that there are forest areas that previously available to the public are no more, and a lot of road building is taking place in wilderness areas. Prison contractors are going up an down roads building things, she said. Regular hunters and tourists are being scared away from park-type areas due to machine gun fire. Big black helicopters have been involved in starting forest fires, but this is covered up. When patients who have been shot are brought into emergency rooms, doctors are refusing to document the weaponry used.
She said that HUD is selling off its property in Portland and a huge portion of HUD's budget is being redirected for CIA and FEMA. She said that some of the contractors in Portland are the same folks who impoded Building 7.
Bechel (I'm not sure I spelled this right) is being issued no-bid contracts to rebuild bridges, she said.
She said she is also concerned about HR 875, the Food Safety Modernization Act of 2009, which could negative impact the food supply. Also, she said that the National Guard has been removed from this area, which she feels makes Portland residents sitting ducks.
I am wondering if, indeed, there are military exercises gearing up for March 11 in this area, and,if so, is the caller correct in that there could be negative environmental impacts? What is the true nature of these exercises, including the duration and scope, and exactly who are involved? What is the mission and where exactly is this taking place? Where is command HQ, who is in charge, and why are the exercises being conducted? Who authorized them?
What the caller said sounds very severe. We need to learn more. I just now got off the phone with her, so I have not yet been able to follow up, but thought this should go out to others who might already know about this and can answer some of the questions.
W. Leon Smith
The Iconoclast
Captain May is a former Army military intelligence and public affairs officer, as well as a former NBC editorial writer. His political and military analyses have appeared in The Wall Street Journal, The Houston Chronicle and Military Intelligence Magazine.
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Located behind a private stone gate lies this magnificent country estate. This amazing home boasts 4,000 SQ FT of living space, ground floor master suite, 5 bedrooms and 4+ baths. Look outside and you will see breathtaking views from every room of the mountains, valleys and sunsets. This home was built for entertaining from its oversized kitchen to its resort style pool. Priced to sell!
# of Bedrooms: 5 *
First Floor Master
# of Full Bathrooms: 4
# of Half Bathrooms: 2
Fireplace(s): 2
Hardwood Flooring
Bonus Room
Guest Suite
Home Office
Single Family Home
Garage Bays: 2
Deck / Patio
Inground Pool
Hills View
Mountain Views
Valley/Canyon View
Heated Pool
Parking / Garage
Pet Friendly


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Chuck Colson remembers "a true prophet for our postmodern age."
WorldNetDaily is selling beautiful boxed sets of "The Chronicles of Narnia."
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DWS: Hillary was most transparent secretary of state ever (*Disclaimer: If you don't count her secret server)
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Of course: Lawyer for ex-Hillary aides is wife of 'journalist' David Gregory
April 4, 2016 06:16 AM by Doug Powers
Dem Debate open thread: Will Hillary take Andrea Mitchell's advice on how to win New Hampshire?
February 4, 2016 05:32 PM by Doug Powers
Anti-Wall St. crusader Hillary Clinton explains accepting $675k from Goldman Sachs: 'That's what they offered'
February 3, 2016 09:43 PM by Doug Powers
Categories: Media, Corruption, Hillary Clinton, 2016 Campaign


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"Stavros, Akrotiri Peninsula" Crete Island by stefepaul
Crete Island Travel Guide: 1,456 reviews and 3,871 photos
I recommend this as a day trip from Chania or for a longer stay for those of you, like me who love those places in Greece with little to do. You can take a bus from the station in Chania east to Stavros in the Akrotiri Peninsula and swim by 'Zorba's mountain', eat lunch at the small cantina on the beach or have a heartier meal at Zorba's 50 meters from the beach. It is surely not the most beautiful beach in Crete (rather a weekend getaway for locals of Chania) but I love swimming below the mountain and apparently there is good hiking for the more adventurous. There is also another cantina called Sunset Beach a perfect spot from which to do just that, watch the sunset. If anyone is interested in staying there, I know of a great place with modest but comfortable apartments. If you are a Zorba fan and you stay in Stavros, you can take a short bus trip into the mountains to visit the village of Kokkino Chorio where Zorba was filmed. There are also nice places to eat in the neighboring village of Plakka.
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Ministry Today proudly presents Greenelines, a new blog from Dr. Steve Greene.
Dr. Greene writes on a wide range of topics important to leaders, church administrators and young leaders in development.
He has lead business organizations, served as a dean of a college of business and lead as a senior pastor. Greene's primary focus is to equip the leaders of saints.Read Greenelines
7 Traits of Churches With Increasing Per Member Giving
What is your experience in church giving?
How to Handle Betrayal and Rejection From Church Members
By Kurt Bubna
When your "Brutus" sticks his knife in your back, choose to act this way by the grace of God.
Here's a Quick Way to Become an Ineffective Leader
If you try to do this, you will almost guarantee your ineffectiveness.
Jesus Is More Attractive Than Mickey
The kingdom of God is not Fantasy Land.
2 Major But Under-the-Radar Changes in American Churches
"I never would have predicted these changes to take place so rapidly."
Your Landing Page Should Land Visitors
By Dr. Steve Greene
When visitors view your website the first time, do you connect with them?
What Sets Apart the Kids Who Stay in the Church?
There is no formula for it, but it's not completely unpredictable, either.
I Will: 10 Realistic Resolutions for 2016
Rather than set unreachable or self-centered goals for this coming year, perhaps you should live by these standards.
Here's the Best Way to Conclude a Sermon
The conclusion to the sermon lets them know that they have heard from the Lord today.
10 Signs You May Need to Take a Day Off
Do any of these apply to you?
Only Those Who Encounter God Can Lead Others to Him
We must be willing to do this if we want to bring others to Christ.
Is There Secret Sin at Youth Gatherings?
Are we tacitly encouraging this during our youth group outings?
LifeWay Study Reveals Some Encouraging News About God's Church
Christ followers who need some good news should take this to heart.
Kingdom Economics: Does Our Spiritual Foundation Have Cracks?
The economy and the world may have weak, damaged or nonexistent foundations. But we are not of the world.
4 Reasons to Plan a Year of Preaching
Planning ahead is vital for several reasons.
5 Big Goals for Each New Year of Ministry
These should help you achieve one huge goal—to make more disciples more effectively.
How to Review Your Year for a Better New Year
If God is searching your heart and examining your mind, shouldn't you do the same?
Faith of the Candidates: An Interview With Marco Rubio
LifeWay Research Executive Director Ed Stetzer sits down with Republican presidential hopeful Marco Rubio.
Raising PKs to Become Disciples Presents Many Challenges
In this fallen world, bringing children up in the fear and nurture of the Lord to become faithful disciples of Jesus Christ will not happen easily, naturally or accidentally.
How to Talk to Your Ministry Kids About Terrorism
While we may wish we didn't have to talk about terrorist acts with our innocent kids, it's a necessity.
9 Surprises in Worship Services That Made Guests Return
You might want to try these if you want people to come back.
8 Christmas Truths for Church Leaders
Let these truths give you strength even if you're struggling through this season.
3 Questions to Discern What I Announce Sunday
By Ron Edmondson
Where should pastors draw the line in choosing what to promote from the pulpit?
3 Things to Remember This Christmas
Here are three principles we should all remember that will help people experience God's love.
7 Ways Satan Tries to Destroy a Church
The enemy certainly loves to disrupt the work of God's people. Here's what you can do.
Powerful Stuff: The Prayers of a Church Leader
Prayer is not a new idea to you, but perhaps God is inviting you to lean in more.
How to Be a Pastor Who Is a Heroic Hill Taker
Pastor, take the time to pray about what hills your church needs to take in the coming year and how to lead the charge.
Kingdom Economics: Don't Get Distracted
The world may be in turmoil, but we are not of this world. God is in control.
One Prayer That Works Every Time
A powerful truth about the kind of prayer God will always answer.
How You Can Reduce Stress During This Wonderful Time of Year
Clinical psychologist Dr. Stephen Galloza gives some reassuring pointers on how to cope with challenging life situations this Christmas.
If I Could Make One Change in Your Church
A wise leader will find ways to help your congregation members do this.
8 More Trends in American Churches in 2016
As a church, you must adapt to change or die. It is becoming that simple.
There's No Place Like Church for the Holidays
Will you invite someone you to know to church at Christmastime? It might make a bigger difference in their lives than you think.
How to Extend a Public Invitation
What can you do to make this a regular part of your preaching experience?
With ISIS Rising, More Churches Making This Controversial Move
"The Bible tells us to be our brother's protector ... it's just another tool."
Would You Love to Speak for God?
There are certain requirements that come with being a prophet.
Ex-Muslim Pastor: All Christians Should Take This Position Against ISIS
"We are the only ones that can take this position and actually make a difference if the church embraces and plays its position ..."
Is This Missing From Your Life?
Critical thinking is stimulated away from the crowd.
Let Earth Receive Her King!
One cannot contemplate the glory of this season without pondering the music that accompanies this most triumphant time of year.
More US Pastors Seeking Election in 2016
Aiming to motivate conservative Christians, they are focusing on smaller political races, local ballot initiatives and community voter registration drives.
In Which Direction Is Your Influence Moving?
Whether it's increasing or decreasing, you've got work to do.
Are You Consistently Inconsistent?
The narrow path has a predictable outcome.
Church Hit With Criminal Summons for Praising Jesus Too Loudly
"We have been consistently hassled by our neighbors and by the parish officials since the first of August - every single week."
8 Trends in American Churches in 2016
Here are some things you will most likely see in the coming year.
New IRS Rule For Ministries Threatens Social Security Number Leakage
If passed, this could cause chaos for the lives of churchgoers across America. This is very serious.
Beware the Hidden Hypocrite
All things hidden, may be revealed on camera.
Kingdom Economics: Say What You Will Do, and Do What You Say
Jesus did exactly what He said. We should follow our perfect example.
7 Ways in Ministry to Protect Your PKs
Here's how you can help to avoid damaging any child growing up in the ministry world.
Discerning 2 Extremes in the Church Today
"This is the reason many churches are dry, dull and listless."
Ministry Life
- Let's Celebrate All Women on Mother's Day
- Memory as Ministry in the Age of Alzheimer's
- An Open Letter to Worship Pastors
- Ministering in the Midst of the Mess
- 5 Keys to Working Well With Your Spouse in Ministry
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- 6 Benefits of a Church Staff Blog
- Healthy Student Ministries Are Character Transforming
- 6 Reasons Why Your Church Offerings May Be Declining
- How to Pray for Your Church as Paul Did
Ministry Leadership
- Leaders, God Wants to Propel You Forward in the Kingdom
- What Is a Volunteer Leadership Culture?
- What Not to Say to a Preacher's Wife
- What Is the Only True Necessity of the Christmas Season?
- Criticism: The Price of Growth
- Kingdom Economics: Confidence Establishes Success
- Why Your Vision Statement Is Overrated
- 6 Steps to Finishing Well in Life and Leadership
- Majority of Pastors Suffer in Silence over Financial Challenges
- When Do You Stop Developing a Volunteer Leader?
Ministry Facilities
- 7 Steps to Make an Effective Pre-Service Video
- How Your Building Is Killing Your Growth
- Growing and Giving in the Digital Church
- 3 Creative Ways to Kill Creativity and How to Get It Back
- 10 Amazing Unseen Things That Can Happen in Your Church Every Sunday
- Impact Ministry: The More-With-Less Church
- The Digital Gospel Goes Global
- Prayerful Consideration: To Build or Not to Build
- How Your Church Can Get an Internet TV Channel
- 3 Reasons for Not Using a Tablet for Speaking Notes
Ministry Outreach
- How to Think Beyond Local Ministry
- 8 Characteristics of Evangelistic Church Growth Leaders
- What We Must Do to Prepare for the Harvest
- 5 Reasons Why the Large, Single-Site Church Is Dying
- Kingdom Economics: Independent Contractors
- What Laypeople Need to Know About Speaking in 'Big Church'
- The Guide to Better Transitions in Your Weekend Services
- Research: Americans Say Christians Face Increased Persecution
- 7 Situations Where Your Church Should Not Have Greeters
- You're Not Perfect, but Neither Was Moses
- Why God Doesn't Want Us to Fear the Unknown
- Breaking Addiction: A New Kind of Recovery Ministry for Your Church
- Your Ministry Journey: Don't Lose the Wonder
- Oral Roberts: God Is at Your Point of Need
- Ed Stetzer: Defining the Church as Evangelicals
- Spiritual Maturity Reaches Way Beyond Salvation
- 10 Ways to Make Visitors Feel Welcome
- Samuel Rodriguez: Lessons From 2012 Election
- The Danger in Living for the Next Big Thing
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Charisma News
- Did Jerry Falwell Jr. Force a Liberty University Board Member Out?
- How This Family With 10 Kids Saw God Move at Azusa Now
- The Next Employment Crisis Is Here: Job Cuts at US Companies Jump 35 Percent in April
- Third Church Burned Down in 4 Months
- Appalachian Awakening Sees Mass Salvations in West Virginia
- Scientists Explain Why It Is Inevitable That America Will Be Hit by Absolutely Monstrous Earthquakes
- What This Unemployed Coal Miner Did Before Confronting Hillary Clinton
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- Low-Salt Diets: More Harm Than Good?


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CAIR- Texas also received a hate call today."We have asked state and federal law enforcement authorities to ensure that Texas Muslims may participate in political activities without fear of attack or intimidation, and they have agreed to boost security for Muslim Capitol Day participants," said Mustafaa Carroll, executive director of CAIR- Texas's Houston chapter. "We appreciate their swift and professional response to the apparent threats."
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Artist: Hadden Sayers
Album: Hard Dollar
Genre: Country
Too many nights on the highway. Too many days on the road. Between a rock and a hard place and still a long way from home.
I'm burnin' up burnin' up with a fever and baby you're the only cure. I'm burnin' up burnin' up with a fever and everything I want is yours. Hey Hey.
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LifeStyle Music, 503 W. Honey Creek Dr., Terre Haute, will host Lori Graves in concert Tuesday, Oct. 16, at 1 p.m.
Graves, a world-renowned artist, is known for her technical prowess.
She started her musical journey on the organ at the age of 5 while growing up in the western suburbs of Chicago.
She won her first state competition at the age of 6, and at the age of 8, she started her formal piano training and continued her classical musical education in organ and piano throughout her college years, finishing with a bachelor's degree from DePauw University.
Refreshments will be served at the event. RSVP's are requested.
For further information, call 812-841-3790.


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May 1, 2016
CHAPEL HILL, N.C. (AP) -- Dexter Strickland scored a career-high 19 points, and North Carolina had five players reach double figures in an 85-60 rout of William & Mary on Tuesday night.
Tyler Zeller and Leslie McDonald added 14 points apiece for the Tar Heels (8-4), who bounced back from a final-seconds loss to Texas by putting the Tribe away with two notable first-half runs.
Harrison Barnes scored 13 points and fellow freshman Reggie Bullock added 11 for North Carolina, which shot nearly 44 percent and took advantage of some awful early shooting by the Tribe.
Kyle Gaillard scored a career-high 25 points on 11-of-14 shooting for William & Mary (4-7).
The Tribe shot 37 percent, but were held to one field goal during a significant stretch of more than 11 minutes of the first half, then didn't get closer than 20 points after the break and finished with 21 turnovers.
Copyright 2016 by The Associated Press. All Rights Reserved.
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text: « BACK | PRINT RS FRONT PAGE CONTRIBUTOR Tax cuts for the rich (Liberal) By: TobyToons (Diary) | September 14th, 2010 at 08:00 AM | RESIZE: AAA Share on Facebook 1 1 SHARES Cross-Posted: TobyToons Denver to Host 2016 RedState Gathering...click here for more information and to Register Today Share on Facebook 1 1 SHARES Tags: Chevy Volt, electric vehicle, GM, government motors, Tax Cut for the Rich Get Alerts COMMENTSPOSTING RULES | LOGIN TO COMMENT | REGISTER TODAY ADVERTISEMENT Pay attention to the West Virginia *Democratic* Primary, too. By: Moe Lane (Diary) | May 1st, 2016 at 10:30 PM | The Democratic primary in West Virginia will likely give us some interesting data on how badly coal is going to hurt Hillary Clinton. Read More » Water Cooler 5/1/2016 OPEN THREAD – Green Zone Protests, AfD Conference, May Day & Baby Parts By: NightTwister (Diary) | May 1st, 2016 at 06:25 PM | Share on Facebook 1 1 SHARES Iraq Green Zone Protests Sunni Muslims have called off their protests in the Green Zone in Baghdad for the time being. Sunni clerics aren't happy with the current configuration of government, and factions aren't happy with each other. The fear of a rift between Shia factions will stoke instability in Iraq, which is already at war with IS. And | Read More » New York Times Trolls Pennsylvania Delegate Count To Keep Trump Revenue Coming By: streiff (Diary) | May 1st, 2016 at 05:30 PM | Share on Facebook 1 1 SHARES I'm not a pollyanna. Ted Cruz is in a tough fight for the nomination. If he loses on Tuesday in Indiana I think the wind goes out of his campaign and Trump goes to the convention with 1,237 delegates and the momentum necessary to stop any attempt to challenge the credentials of his delegates and, ultimately, ultimately he takes | Read More » No, You're Not Really Moving If Trump Wins By: Kimberly Ross (Diary) | May 1st, 2016 at 05:00 PM | Share on Facebook 1 1 SHARES Every presidential election cycle, celebrities and regular-folk alike claim that if a certain candidate wins, they'll move elsewhere. The temper tantrum may sound good, but no one actually follows through with it. Most recently, actress, producer, Hillary Clinton superfan, and all-around feminist maniac Lena Dunham declared she would indeed move to Canada if Donald Trump became president. As CNN reported: "I | Read More » Donald Trump Says Mike Tyson Is Not A Rapist; Chris Wallace Goes Along With Him (VIDEO) By: streiff (Diary) | May 1st, 2016 at 04:01 PM | Donald Trump calls Ted Cruz a liar for saying Mike Tyson is a rapist. Fox News's Chris Wallace just goes along with him Read More » REDSTATE COMMUNITY ALL COMMENTS POPULAR #RSRH In Which the Conservative Organ NYTimes Anoints Transgenderism with Napalm By: CincoSolas_del_Bronx Ted Cruz's Only Hope for Indiana and Beyond: "The Government didn't build the American Dream…" By: imperfectamerica The Long Con By: Freedoms Truth Let's dispel the notion that we can vote for Trump because "Supreme Court" By: Soandso Is This a Sequel to Idiocracy? By: sdsali Figuring Out Indiana By: davenj1 Transgender Bathrooms By: Joseph Michael Donald Trump's "What difference does it make?" moment with conservatism By: southernconstitutionalist Water Cooler 5/1/2016 OPEN THREAD – Green Zone Protests, AfD Conference, May Day & Baby Parts By: NightTwister Media Power Unhinged By: John Vernon Why a Donald Trump Presidency Might Be Like a Vin Diesel Movie By: blbennett John McCain Promotes SpaceX Rocket Launches Above National Interest By: Dean Chambers Democrisy: Hillary Clinton and #HB2 By: Dana Pico A Look at Last Tuesday's Down Ticket Primary Outcomes By: davenj1 The Media Have Chosen Their Destructor By: evilbloggerlady I hate to say it, but I believe Hillary Clinton will be the next president By: cantenucci04 Eleven Reasons to Dislike Lena Dunham By: davenj1 Transgender Bathrooms and the Two Minute Hate By: sdsali TO: Jay Cost – YouTubify your Storify By: Martin Knight Cruz Positioned to Win California By: sdsali My California Calls for Cruz By: sdsali M-x dissociated-trump By: Finrod Water Cooler 4/30/2016 OPEN THREAD – Trump, Anti-Trump and #NeverTrump By: earhartam Cui Bono? By: Spartan Conservative Stand and Deliver – Paul's Message to Peter By: drrobertowens Gubernatorial Races in 2016- April News By: davenj1 Why does John Boehner hate Ted Cruz? By: evilbloggerlady Conservative Media and The Importance of the Truth By: ArchTriumph Water Cooler 4/29/16 – Carly Fiorina – Cancer Survivor, Business Warrior, Faithful Believer By: apkyletexas Bobby Knight Throws Another Chair By: gopcongress Open Letter to Donald Trump By: Imre Beke The Battle for the Senate in 2016- April News By: davenj1 Dear Trumpsters Will Please Go Back To Being The Principled Conservatives I Know You Are By: Ulysses Arn Hey, Donald: If this Thing is over & Ted is "Eliminated" Why Not Take Your Name off the Ballot in California? 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N. American PET bottle resin prices fall 7 cents
AKRON, OHIO — A recent drop in North American PET bottle resin prices is featured in this week's Material Insights video. Also this week, we report on polyethylene supply issues impacting two material firms, as well as news that sustainable chemicals maker BioAmber Inc. raised $80 million in an initial public offering of its stock.
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noondaywitch Jul 1, 2012 8:10 AM
in response to felitafromchandler
I've asked the mods to relocate this to the MacBook Air forum. This one is for iMacs from 1998 to 2005.
captfred Jul 1, 2012 8:38 AM
in response to felitafromchandler
Look in System Preferences > Displays. If the Arrangement tab is missing then the MBair probably has a bad or improper connection to the TV. If the tab is present then the MBair reconizes the connection. Turn the tv tuner to the proper HDMI input and you should see the "galaxy" wallpaper.
This would be extended desktop mode or a logical extension of the desktop to the right of the MBair monitor. Drag an app off the right side of your screen and it appears on the TV.
Toggle CMD F1 to switch between extended desktop and mirror modes.
HelpMikel Jan 7, 2013 12:40 PM
in response to captfred
help in troubleshooting Macbook to Sony HDMI... I HAVE had the miniport/ HDMI cable connection working - I just plugged it into both ports and it worked - i.e. No fussing with "settings". Now, after kids hooked up Wii game – computer to TV does not work…
My <system preferences> -> Display -> detect displays does not register any connection [alert: the arrangement tab of Display preferences is hidden because you only have a singe display attached to this computer].
Q? is it the computer that does not recognize hookup or is it the TV that does not recognize the hookup?
I have done all the standard go online for answers: reboot both, turn off both, connect cable, check input to HDMI, reset PRAM,
Still no success…
Your suggestions …??