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Home » Under Secretary for Public Diplomacy and Public Affairs » Bureau of Public Affairs » Bureau of Public Affairs: Publications » Photo Gallery » Secretary of State Hillary Rodham Clinton Photos » 2011 Secretary Clinton's Photos » Secretary of State Clinton Photos: August » Photo: Secretary Clinton Speaks on Syria
Secretary Clinton delivered remarks on the situation in Syria today at the State Department. State Department photo by Michael Gross.
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Pressure vessel temperatures at the No.1-3 units
May 31, 2013 (Friday)
The serious situation remains unchanged, in that workers still have to cool nuclear fuel with water at the melted-down No.1 to No.3 units of the Fukushima Dai-ichi Nuclear Power Plant. For your information, this blog continues to record temperatures measured at the lower part of the pressure vessel of each unit. Temperatures between May 25 and May 31 are posted on the following page.(Source: TEPCO)
投稿者:かぶん | 投稿時間:17:33 | カテゴリ:Data of the Fukushima Daiichi
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May 6, 2016
The "side-by-side" shakes split two flavors in one glass. They're the latest in a line of new products from the Indianapolis-based restaurant chain.
New offerings such as peach-flavored milkshakes and shots of hot fudge are among the products, which may help Steak-n-Shake dish up continued sales success.
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Homestead winner and Sprint Cup Series champion Kyle Busch ended the season on top of the Power Rankings.
[WARNING: The following story contains spoilers from Monday's episode of Castle. Read at your own risk.] Christmas came a little early for
[WARNING: The following includes spoilers from Monday's winter finale of Blindspot. Read at your own risk!] The
[Warning: The following contains spoilers for Monday's episode of Jane The Virgin. Read at your own risk!]
They're systematic, hydromatic, ultramatic...why, they're Grease-d lightning! We've finally seen the first images of the cast of Fox's
Here we are: Bindi Irwin and the boys have made it all the way to Part 1 of the
Kristin Cavallari and her husband, Chicago Bears quarterback Jay Cutler, got the biggest and best gift...
Criminal Minds star
Scott (Tyler Posey) and his pack - once he reassembles it - will be battling The Beast when MTV's
[WARNING: The following contains spoilers from Monday's episode ofSupergirl. Read at your own risk!] Lucy Lane may have gotten her man, but her troubles are just beginning. On Monday's
Actor Reid Ewing, who plays
Cheboygan Directory
Business Name
Location, ST | website.com


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The Power of Independent Thinking
The Supreme Court and the Battle for Second Amendment Rights
Recorded: Thursday, July 22, 2010
In June 2008 the U.S. Supreme Court handed down a landmark ruling on the Second Amendment individual right to keep and bear arms with its Heller v. District of Columbia decision. Two years later, in June 2010, a second historic decision squeezed through the highest court in the land.
Experts: Stephen P. Halbrook, Donald E. J. Kilmer Jr.Type: Independent Institute EventIssues: Bureaucracy and Government, Civil Liberties/ Human Rights, Constitutional Law, Criminal Justice/ Prisons, Culture/ Society, Gun Control, History (U.S), Law Enforcement, Litigation, Political Ideology and Philosophy, Race Issues
A Gala for Liberty: The Independent Institutes Gala Reception and Dinner
Recorded: Tuesday, September 16, 2008
On September 16, Archbishop Desmond Tutu, actor and director Andy Garcia, and entrepreneur William K. Bowes, Jr. were honored at the Independent Institutes A Gala for Liberty. Each honoree received the Alexis de Tocqueville Award in recognition of their contributions to advancing the ideas and ideals of liberty, entrepreneurship, innovation, and peace.
Experts: George B. N. Ayittey, Michael J. Boskin, William K. Bowes, Jr., Andy Garcia, Archbishop Desmond M. Tutu, Alvaro Vargas LlosaType: Independent Institute EventIssues: Business, Civil Liberties/ Human Rights, Collectivism, Culture/ Society, Democracy, Diplomacy and Foreign Aid, Economic History and Development (International), Free Market Economics, Free Speech, Freedom, Government Power, History (International), Latin America, Political Ideology and Philosophy, Race Issues, Religion, Taxes, Terrorism and National Crises, Trade


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LINENSAll linens are furnished in all Guest homes. Beds have good quality sheets, blankets, pillows, and bedcover (either classic white cotton throws or handmade quilts by Mrs. Ross). We also have old bedcovers for the four footed bed companions. Many guests comment on how comfortable the beds are and last summer, a 10 year old boy came to the office to tell us "we had the best beds!"TOWELS Towels are provided for the bathrooms and kitchens, enough for the number of people expected and more if needed. Fresh towels are replaced daily. Blue swim towels are in the office, just return your used/wet towel and grab a fresh one. We also provide old towels for the four footed members of the family. DAILY TOWEL SERVICE and TRASH REMOVALDaily towel service is provided for all guests and in all accommodations. Housekeeping comes to the guest homes everyday to remove wet towels from the bathrooms and replace with fresh towels. They also remove the trash to the outside bin, so it can be taken away at 4pm everyday (cuts down on critters knocking over trash cans in the middle of the night). Every 3-4 days there is a sheet change on beds (unless waived by the guest), as well as a cleaning of bathrooms, and replenishment of soaps (hand and dish) and paper products (toilet paper, paper towels, kleenex). We do not provide personal amenities such as shampoo. Most of our guests prefer to not have the interruption of daily bed making, however we are happy to provide daily housekeeping (includes making of beds and cleaning bathrooms) if you prefer, for an additional fee of $23 per bedroom per day. KITCHENSAll kitchens are equipped with refrigerator, toaster, coffee maker and microwave. Full kitchens (available in all but 3 guest homes) have regular range, all dishes, flatware, pots, pans & utensils. Housekeeping does not do dishes. Mini kitchens (in the 3 small guest homes; Aspen, Tamarack, and Butternut), do not have dishes, flatware, or cooking utensils.
FIREPLACESOur fireplaces burn real wood! They are not gas, electric or remote controlled! Unlimited wood for fireplaces is furnished at no charge and is next to the cabin.
OUTSIDE FIRE PITSAlmost all the guest homes have a designated outside fire pit, either next to the cabin or shared with the cabin next door. Please be aware of the area's current fire danger or ask the office. Please always practice responsible fire safety and NEVER leave a fire unattended... just like the boy scout manual tells us.
FANS and AIR CONDITIONINGOnly two of our guest homes have central air conditioning - Whistle Wings (2 bedroom) and Wood Duck (3 bedroom). However, there are many ceiling fans, many floor and window fans and usually a wonderful breeze from the west, across the lake, and good cross ventilation. Our nights are generally cool.
KEYS and LOCKS Ross' Teal Lake Lodge has always been considered a safe and private property. There are locks on the cabins, if you want to lock from the inside, but we do NOT use keys (never have in 100 years). If you have valuables that you are uncomfortable leaving in the unlock cabin, we suggest keeping it in the car, or giving to the office to lock up.TV and VCR/DVDEvery guest home has a TV. However, with the switch to Digital TV, it has left the northwoods with NO local channels. (Sorry, we are 90 miles from the station, and no converter box can reach that far!). We have DIRECT TV available in all public places, for weather and news updates, or to watch the game. The Captains Cabin bar or Golf Gazebo are great places to watch the game. The TV in the Main Lodge is usually turned off, but can be turned on for a quick update on weather and news. We discovered that this seems to work for most of our guests. Fox Den (our 4 bedroom cabin) and the Cinnamon Suite are the only units with Direct TV... so if it is important to your party, let us know.
We do offer FREE rental of DVD's and VCR's, or you may bring your own. We also have a few movies to borrow, but our selection is limited. GRILLSWe supply Weber Charcoal Grills upon request at a charge of $5 per day - you supply the charcoal. Weber "Q" Gas grills are available at a charge of $15 per day - we supply the gas.GUEST LAUNDRY FACILITIES Washer and Dryer are available for guest use in the historic wash house (remodeled of course) near the Main Lodge. Just sign a charge slip for $3/load, and it will be put onto your bill. We do ask that people be considerate to other guests, and not forget about their laundry. BABYSITTINGBabysitting service is usually available, but please give our office 24 hour notice.PETSWell-behaved pets are welcome at Ross' Teal Lake Lodge. see Pets Welcome . There are two guest homes designated as NO PET, for those with allergies; Tamarack and Whistle Wings. However, thanks to our diligent housekeeping staff, it is rare to ever find dog hair in any of the guest homes. ON-PREMISE MANAGEMENT and FRIENDLY STAFFThe Ross Family lives on property and are active in day-to-day operations. This allows us to see our guests everyday and be readily at hand to meet any of requests or concerns. There is also a friendly staff of 25 people, some who live on property, who are always available; whether it be to bring extra towels, gas a boat, or answer questions. COMMUNICATIONS with the outside world - Phones, Web Access, FaxTeal Lake is an escape from the craziness of the outside world, and we try to keep it at an arms length, so guest feel it is a TRUE vacation. For those that need to keep in touch with the outside while on vacation, we do provide 21st century communication, we just keep it hidden. See our Communications link for details.


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Jaeger-LeCoultre is where a woman has her Rendez-Vous with time. With its feminine creations the Joux Valley manufacture crystallizes the meeting of Fine Watchmaking and High Jewellery, dreaming up pieces to accompany daily living, to grace an evening or share exceptional moments. This year, the Rendez-Vous and Reverso collections are putting on a more seductive look. Complicated, ultra-thin, mechanical, they concentrate the freedom of creation and the watchmaking know-how and craftsmanship that have served the Grande Maison for 180 years.
Rendez-Vous Perpetual Calendar
Eternity within your hand's grasp. The Rendez-Vous Perpetual Calendar displays infinite time. Driven by the self-winding movement Jaeger-LeCoultre 868 Calibre, visible through the sapphire case back, its dial lays out the complexity of time with disarming ease. The sober design combines within its 37.5 mm diameter classic elements and the aesthetic inspiration of the Grande Maison. Legibility is perfect.
Rendez-Vous Tourbillon Night & Day
Is your eye drawn to the hypnotic motion of the tourbillon? Or by the gracefully changing Day-Night indication? While the hours and minutes move forward at their leisurely pace, the time is also expressed in these additional complications. Carrying on from the Rendez-Vous Tourbillon models presented in previous years, the new Rendez-Vous Tourbillon Night & Day has chosen to lighten its hour chapter of the normal separations between the numerals inspired by the 1930s in order to better showcase the complications.
Rendez-Vous Tourbillon Wild
Right from the start, the rare crafts of the Grande Maison have striven to beautify the hours displayed on watches. Combining their know-how, pushing the limits of creativity and ingenuity, they have seen the emergence of pieces that would stop time in its tracks. The Rendez-Vous Wild is a new creation that invites several of these age-old crafts to combine their talents to stir up the emotions.
Grande Reverso Lady Ultra Thin Duetto Duo
It features among the 400 patented by the Grande Maison over the past 180 years. The Duetto Duo pushes the limits of design. Reversible, with double aesthetic, double time zone, one single mechanism, and now ultra-thin: the challenge was only equalled by the ingenuity of Jaeger-LeCoultre's watchmakers. Dreamed up exclusively for the female, the Grande Reverso Lady Ultra Thin Duetto Duo brings extreme delicacy to the complexity of its mechanism. Its svelte lines come in three versions - steel, white or pink gold, in a case which elegantly fits onto the slenderest wrists thanks to its curved lugs.
Grande Reverso Ultra Thin High Jewellery
Dressed in pink or white gold, the body of the new Grande Reverso Ultra Thin High Jewellery is sprinkled with over 90 diamonds. Set by hand, the reversible case flaunts its 7.87mm thin profile. It fits like a second skin onto the wrist thanks to its curved lugs. The natural mother-of-pearl dial plays on its iridescent glints. An exquisite setting for the appliqué Arabic numerals whose dancing calligraphy softens the geometry of the case. The white gold model comes with a white alligator skin strap which adds a fresh elegance to the watch's personality. The pink gold version extends onto a gold bracelet whose links offer perfect suppleness to the wearer for a smart contemporary effect.
Reverso Cordonnet Duetto
Decorated by the rare crafts of the Grande Maison, this new High Jewellery creation exalts the Duetto concept in a blaze of over 1250 diamonds. Inspired by a Jaeger-LeCoultre model from 1936, this jewel watch plays a symphony of aesthetics and technique. Fully gem-set, the Reverso Cordonnet Duetto encloses the wrist in its perfectly fluid cord strap. That is the complete beauty of the ultimate in watchmaking magnified by the jeweller's art.
With the passing centuries and passing fashions, woman has determined the aesthetic of the time and how to wear them, yet she has also made her own demands for innovations and complications and married beauty and function, thus letting watchmaking draw from the art of jewellery to emancipate itself. The new Rendez-Vous and Reverso are the proof of this. They in turn write a new episode in the ceaseless creativity of the Grande Maison. Proving that time and its complexity are not just intended for man.


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The Man Behind Santorum: Who Is Foster S. Friess?
To run for president in this election cycle, it seems, you must have the backing of a super PAC, often heavily supported by a single super-wealthy benefactor. We've all learned lately about Newt Gingrich's billionaire sugar daddy Sheldon Adelson. Now it's time to meet Rick Santorum's No. 1 fan, Foster S. Friess.


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There are 171 results - Show results on a map Print this page
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Steeped in history, this former coaching inn enjoys a peaceful rural location close to Windermere. Public areas include a welcoming lounge and a cosy bar where an extensive choice of wines, ales and w...More about The Wild Boar Inn, Grill & Smokehouse
Dating from the 17th century this former inn lies in the town centre. Now a family-run hotel, it provides attractive well-equipped bedrooms with WiFi access. At lunch a menu ranging from snacks to ful...More about Kings Arms Hotel
Sawrey House Hotel was built in 1830 for a vicar who was to become the headmaster of the nearby Hawkshead Grammar School. It's ideally located in the peaceful village of Near Sawrey, next to Beatrix P...More about Sawrey House Hotel
Close to the town centre, Elm Tree Lodge is a tastefully decorated Victorian house that offers a variety of rooms. Bedrooms feature stripped pine, period furniture, crisp white linen and modern en sui...More about Elm Tree Lodge
This stylish house, built in the late 1700s, is situated in 67 acres of grounds and enjoys an elevated position overlooking Lake Windermere. The spacious, beautifully furnished bedrooms and suites, so...More about The Samling
Located on the border between England and Scotland, Premier Inn Carlisle Central makes a good choice to break a long journey. If you have time to spend in the area, shop at Lanes Shopping Centre, visi...More about Premier Inn Carlisle Central
Guests are assured of a warm welcome at this well-maintained property in attractive gardens set back from the road. Bedrooms are sensibly furnished and include a delightful honeymoon suite. The proper...More about Surrone House
Historic photographs commemorate the fact that this delightful house was once the family home of Beatrix Potter. Secluded in landscaped grounds, it enjoys views across the valley and Lake Windermere. ...More about Lindeth Howe Country House Hotel & Restaurant
Skygarth is just south of the village, half a mile from the busy main road. The house stands in a cobbled courtyard surrounded by cowsheds, with gardens to the rear, where red squirrels feed. There ar...More about Skygarth Farm
Nanny Brow provides high quality throughout. Each room is thoughtfully decorated with contemporary furnishings, antique furniture, and original arts and crafts. The property is situated in Clappersgat...More about Nanny Brow


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this wiki
|Come back inside; there's nothing you can do.
|Biographical information
|Physical description
|Circuitry Color
|Other information
|Vehicle maintenance
|Out of universe information
|Reginald VelJohnson (voice)
|TRON: Uprising
Able is a supporting character of TRON: Uprising voiced by Reginald VelJohnson. Beck's "grandfather" type figure, Able owns and runs the garage where Beck, Zed and Mara work. As one of Flynn's first programs, he is the elder statesman of Argon Sector. He is constantly worried about Beck and what the future may hold. Able was murdered by Cyrus at the Dock.
Able was one of the first programs created by Kevin Flynn. He is an elder and statesman of Argon Sector. Able owns a garage, devoting his life to the maintenance of vehicles, but when Clu's forces took over, things changed. Able was upset when one of his employees was derezzed after an argument with a guard, but urged the rest to stay calm, thinking that there was nothing he or anyone could do. He kept this policy even when Zed and Mara were captured by Clu's forces, but was nonetheless relieved when they returned, saved by the Renegade.
Able ran a tight business, scolding Beck for missing work and sending Hopper and Bartik away when they attempted to intimidate his workers. He couldn't refuse repair jobs for General Tesler and his troops, and even delivered a giant tank to Tesler's ship in person, but made it clear that the Occupation's disrespectful behavior was not welcome.
Able recognized the distinctive T symbol worn by both Tron and the Renegade, and, upon being returned to the garage with injuries sustained during one of the Renegade's fights with Tesler, told his employees that it was Tron who saved him. However, after repeated failed attempts to keep Beck out of trouble, he eventually disclosed that he had known for a long time who the Renegade really was. He then contacted Tron, whom he had secretly been helping for a long time to maintain his healing chamber in the Outlands, and threatened to cut off his support if Tron kept involving Beck in the rebellion, insisting that they both knew how this would end and refusing to let Beck become "one of your mistakes." Though Tron would not compromise, he and Able fought back-to-back when a swarm of gridbugs attacked, and Tron lent Able his snowmobile when they parted.


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Clean Power Plan May Yield Billions in Economic Benefits and New Jobs
Earlier this month, the Environmental Protection Agency (EPA) released their proposed Clean Power Plan. As readers of this blog are already aware, the Clean Power Plan proposes carbon emission standards for coal-fired power plants, which are the single largest source of carbon pollution in the U.S., generating approximately one-third of all domestic greenhouse gas emissions. Some specifics are that under the Clean Power Plan, states must expand their energy sources and use solar (photovoltaic and solar thermal), wind, geothermal, sustainably sourced biomass, biogas, and low-impact hydrology in order to decrease their carbon emissions.
Did you know that renewable energy technologies are characteristically more labor-intensive than intensely mechanized fossil fuel technologies? This means that the potential economic benefits may be substantial; not to mention the significant benefits for our climate and health.
The solar industry employed over 100,000 workers in jobs ranging from solar manufacturing and sales to installation according to the Solar Foundation in 2011. Solar jobs grew by 20% percent in 2013 and 2014 is expected to create 22,000 jobs. Furthermore, these statistics were reported before the EPA plan was released, which may further boost the renewable job sector.
Let's look at wind energy. The amount of domestically manufactured equipment used in wind turbines doubled from 35% in 2006 to 70% in 2011 with 560 factories directly employing 75,000 full-time employees.
The hydroelectric power industry also plays a role. Statistics show in 2009 it employed 250,000 people. As many as 700,000 jobs could be generated if the hydropower industry installs a new capacity of 23,000 – 60,000 megawatts (MW) by 2025. Rounding out our look at the renewable energy sector, the geothermal industry directly employed 5,200 people in 2010.
The Union of Concerned Scientists (UCS) estimated in 2009 that a national, renewable electricity standard attempting to cut 25% of carbon emissions by 2025 would generate 297,000 jobs, $263.4 billion in new capital investment, $13.5 billion in income to farmers, ranchers, and rural landowners, and $11.5 billion in new local tax revenues. Remember, the EPA proposed reducing carbon emissions from existing power plants by 30% below 2005 levels by 2030. So the potential economic benefits may increase over the UCS's estimates.
With these figures, we're not even taking into account a complete picture of the potential economic benefits from expanded renewable energy sources. Think about how direct job creation leads to indirect job creation. For example, when you hire additional employees, you may very well need a larger Human Resources staff.
All of this comes at a time when our country could deeply benefit from economic stimulation. The U.S. economy is still anemic, with unemployment rates remaining high, and a disturbing national debt that's expected to reach $20 trillion by 2020. We must embrace win-win scenarios such as these that combine healing our ailing planet with economic recovery. It's past time to forge the path to a low-carbon future.
Much Anticipated Carbon Pollution Standards Proposed
The big news this week is that the Environmental Protection Agency (EPA) released their proposed Clean Power Plan. Environmental groups and climate change activists have been eagerly awaiting these carbon emission standards for coal-fired power plants.
Power plants are the largest source of carbon pollution in the U.S. and generate approximately one-third of all domestic greenhouse gas emissions. The EPA's proposal, released Monday, will help lower carbon emissions from existing power plants by 30% below 2005 levels by 2030.
The proposed rules are the latest under President Obama's Climate Action Plan. The EPA is charged with proposing commonsense approaches to reduce greenhouse gas emissions from new and existing power plants.
Last June, President Obama announced a series of executive actions to reduce carbon emissions, prepare the country for the impacts of climate change and lead international efforts to address global warming. Learn more about the President's Climate Action plan on the White House web site.
For good or ill, climate change continues to be a politically charged issue, often dividing along party lines. However, many companies recognize that global warming is already impacting their daily business operations and that the problem is only going to get worse if we do not take steps now to embrace a low-carbon future.
Sustainability advocacy nonprofit Ceres coordinated letters of support for the EPA's proposed carbon pollution rule to the Obama Administration and Senate and House majority and minority leaders from 125 companies including the likes of Unilever, VF Corporation and Mars. The letters were also signed by 49 investors managing $800 billion in assets.
Read more about the EPA's proposed Clean Power Plan at http://www2.epa.gov/carbon-pollution-standards/clean-power-plan-proposed-rule.


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May 5, 2016
GREENVILLE, N.C. - The scheduled non-conference baseball game today at Old Dominion has been cancelled due to rain and wet grounds Monarch officials announced Wednesday morning. The two teams will attempt to make-up the game at a future date.
ECU (7-4) will be back on the diamond Friday, Mar. 8 when it plays host to Monmouth (2-5) in the first of three games. First pitch is scheduled for 5 p.m. (EST).
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The Lewisville Library provides eight public-access computers.
They access the Internet and Microsoft Office® applications: Excel, Powerpoint,
and Word.
Two Early Literacy Stations are available to children in the children's area. These
computers feature educational games for preschoolers through third grade.
A Digitization Station provides digital conversion equipment for use by our customers.
A special State Library grant funded this additional computer workstation. As a
result, the efforts for Digital Forsyth will continue to add historical treasures
to your family and our community.
Forsyth County Public Library provides computer services and wireless internet access
at all locations for any public use. Review the Internet Use Agreement & Computer Rules.
Specialized workstations and software are available at some locations:
Assistive Technology, nonprofit and grant research,
digital conversion,
genealogy assistance, and much more. Computers can be reserved at Central
Library for research. Let the Library fill many of your computing needs.
6490 Shallowford Road
Lewisville, NC 27023
(336) 703-2940
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10:00 - 9:00 Monday
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For years, I've heard numerous friends wax poetic about David Chang's legendary Momofuku restaurants. Even non-foodie friends have raved to me about it. Alas, I have never been there. And feeling left out, I've tried to get in the act by buying Chang's cookbook and recreating some of his popular recipes. But there was one recipe that I was dying to try, and just never had the opportunity to – until now. Yes, dear readers, I have finally (and successfully) made, drooled over and scarfed down Momofuku's Steamed Pork Buns. And everyone was right. They are incredible!
One of the reasons I'd never tried Chang's recipe was because it's long. Long recipes scare me. They translate to "very complicated", "tedious" and… well…"long". This recipe is really none of those things. Okay, maybe it is a little long, but it isn't complicated or tedious. And once you break it down by component, it's actually quite manageable. While these steamed pork buns would never qualify as a quick, week night dinner, they're definitely worth a go when you have more time to spend.
Another reason I'd never made these buns before is because pork belly is scare around these parts. I can usually find it frozen, but rarely ever fresh. I hate to buy frozen meat. I hate to buy fresh meat and freeze it too. It's just one of my little quirks. Don't judge me.
A few weeks ago, I stopped into Whole Foods to stock up on my favorite yogurt. As I passed by the meat counter, I glanced over to admire the meat, and lo and behold – I saw fresh pork belly. I think my heart skipped a beat. I sidled up to the counter and picked up a few pounds, knowing exactly what I would make with them. Seriously, if I had known then how fab this recipe would turn out, I would have bought more! read more >>
Filed Under: Asian, Cooking, Muffins, Biscuits and Scones, Pork, Recipes


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Best Ever Cutout Cookie Recipe
Posted on November 16 2010
This is hands down our favorite cutout cookie recipe, and one of our top 10 best baking finds! It tastes buttery and delicious, and works well for thin or thickly rolled cookies. Its best feature is that because it's really a shortbread cookie, it holds its shape perfectly through baking. Have you ever made cutout cookies and your Christmas tree cookies end up looking like funny clouds cause they spread so much during baking? That won't happen with this recipe.
Sugar Cookies:
2 sticks unsalted butter, softened
1 cup confectioner's sugar
1 egg
1 tsp vanilla extract (or any other flavoring)
2 1/2 cups flour
1 tsp salt
Cream butter and sugar. Add egg and blend well. Add extract and blend. Mix flour and salt and gradually add. Cover dough with plastic wrap (we usually put ours in a gallon size Ziploc bag) and chill dough for about 2 hours. Working with about 1/3 of the batch at a time, briefly knead the chilled dough and roll about 1/8 inch to 1/4 inch thick. Cut out shapes. Bake cut out cookies on parchment lined cookie sheets at 375 for 12-14 minutes.
You can also freeze the dough. After mixing, put dough in a gallon size Freezer ziploc bag (or wrap well) and freeze. Thaw overnight or for at least a few hours in the refrigerator in the ziploc bag. If too chilled to handle, let sit at room temperature for about 1/2 hour to 1 hour until it's workable. Chilled is good, though, don't let it get too warm and soft.
We found this recipe over at The Decorated Cookie, check out her blog for tons of fun cookie ideas. We are so glad she shared it.. this is our cutout cookie recipe for life!
• • those cute Paper Tags are available in our shop • •
• • Tomorrow • • Just a Little Soft Royal Icing Recipe • •


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ASKA AMP-36GT 36 dB Distribution Amplifier 40-1000 MHz Bandwidth Gain Control FM Trap Aluminum Housing Medium to Large Systems, Part # AMP36GT
The AMP-36G distribution amplifier is designed for use in medium to large distribution systems of 40 - 1000MHz bandwidth. Variable gain control (10dB) and switch-able FM trap (24dB) provides excellent system configuration. Specification engineered to maintain stable and high signal quality signals. Auminum housing and UL listed
Retail Price: $45.95
Our Discounted Price: $34.45


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|February 18, 8:00 AM - 9:00 PM - Add to Calendar
|Visual Performing Arts
|VPA , Visual Performing Arts , Gabbard , VCD , gallery
Most of the people of Cienfuegos live without running water or electricity. In the face of sheer, abject poverty Visual Communication and Design continuing lecturer and photographer James Gabbard has captured a colorful zest for life and the pride of these people surrounded by the rain forests of the Dominican Republic.
Feb. 18 - March 17, 2013
Symposium with Reception: February 21 VA 204
IPFW Visual Arts Gallery
The exhibition is free and open to the public. Gallery hours are 8 a.m.–9 p.m. weekdays and 10 a.m.–5 p.m. weekends. Admission is free for everyone.
For information call the Department of Visual Communication and Design at 260-481-6709 or visit www.ipfw.edu/vcd
There are no related events.


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Justice Design Group CER-0950W-STOA
Agate Marble 13.5" Large Rectangular One Light Exterior Wall Sconce from the Ceramic Collection Rated for Wet Locations
Item # BCI1727669 | Model # CER-0950W-STOA | Ceramic Collection
We still have product details, accessories, replacement parts and reviews below, scroll down to see them!
Questions about Justice Design Group CER-0950W-STOA?
Contact us for advice or more details. Our product specialists are here to help.
Ambiance 13.5" Large Rectangular One Light Exterior Wall Sconce from the Ceramic Collection Rated for Wet Locations
This functional 13.5" wall sconce from the Ambiance Collection is rated for wet locations and exterior use. For your convenience this sconce is offered in a multitude of finishes and the unfinished ceramic finish option (Bisque) is paintable, allowing you to customize this fixture to suit any exterior. The open bottom of this fixture allows light to wash down your walls and the multiple lamping options allow you to design this sconce to fit your lighting needs.
From an elegant lamp atop a contemporary end table to a dramatic sconce illuminating a formal entryway, Justice Design offers a wide array of lighting solutions for residential and commercial settings. Create a mood, complement a theme, or simply add the perfect accent with a Justice Design decorative lighting fixture. With over 200 different shapes and more than 35 different finishes, you can customize our fixtures to suit any decor. From paintable Bisque to faux finished masterpieces hand crafted by skilled artisans, Justice Design offers endless design possibilities for any environment - indoor or outdoor.
- Suitable for Wet Locations
- Closed Top
- Made in the USA
- This item is available in up to 30 hand-painted finishes
- The unfinished ceramic bisque (BIS) is paintable
- Standard Incandescent Lamping: (1) 100W A-19 Max
- Fluorescent Lamping: (1) 26W GU24 Max
- Fluorescent Non-Dimming GU24: 13W Lamp (optional)
- Fluorescent Dimming GU24: 15W Lamp (optional)
- Overall Dimensions: 13.5" High x 7.25" Wide x 6.5" Extension
- Mounting Center: 6.75"
Additional Justice Design Group Links
- View the Manufacturer Warranty
- Browse All Justice Design Group Products
- Justice Design Group Ceramic Collection
This Justice Design Group item can also be referenced by the following color/finish specific model #:
- Justice Design Group CER-0950W-STOA*
Agate Marble
- Justice Design Group CER-0950W-ANTC*
Antique Copper
- Justice Design Group CER-0950W-ANTG*
Antique Gold
- Justice Design Group CER-0950W-PATA*
Antique Patina
- Justice Design Group CER-0950W-ANTS*
Antique Silver
- Justice Design Group CER-0950W-BIS*
- Justice Design Group CER-0950W-CRB*
Carbon - Matte Black
- Justice Design Group CER-0950W-STOC*
Carrara Marble
- Justice Design Group CER-0950W-CKC*
Celadon Green Crackle
- Justice Design Group CER-0950W-BLK*
Gloss Black
- Justice Design Group CER-0950W-WHT*
Gloss White
- Justice Design Group CER-0950W-GRAN*
- Justice Design Group CER-0950W-TRAG*
Greco Travertine
- Justice Design Group CER-0950W-HMBR*
Hammered Brass
- Justice Design Group CER-0950W-HMCP*
Hammered Copper
- Justice Design Group CER-0950W-HMIR*
Hammered Iron
- Justice Design Group CER-0950W-HMPW*
Hammered Pewter
- Justice Design Group CER-0950W-SLHY*
Harvest Yellow Slate
- Justice Design Group CER-0950W-MAT*
Matte White
- Justice Design Group CER-0950W-TRAM*
Mocha Travertine
- Justice Design Group CER-0950W-NAVR*
Navarro Red
- Justice Design Group CER-0950W-NAVS*
Navarro Sand
- Justice Design Group CER-0950W-RRST*
Real Rust
- Justice Design Group CER-0950W-PATR*
Rust Patina
- Justice Design Group CER-0950W-CKS*
Sienna Brown Crackle
- Justice Design Group CER-0950W-STOS*
Slate Marble
- Justice Design Group CER-0950W-TERA*
Terra Cotta
- Justice Design Group CER-0950W-SLTR*
Tierra Red Slate
- Justice Design Group CER-0950W-VAN*
Vanilla (Gloss)
- Justice Design Group CER-0950W-PATV*
Verde Patina
- Justice Design Group CER-0950W-CRK*
White Crackle
*Discontinued model or finish
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Deputies with the Alamance County Sheriff's Office said a shooting case that began as a suicide investigation is now a murder investigation.
That's because, early Wednesday deputies responded to a reported shooting at a house on Sartin Road. When they arrived at the home, officers found 33 year-old Anthony Eric Williams with a gunshot wound to his head. He was taken to Moses Cone Hospital where he died shortly after.
During the preliminary investigation, officers believed the shooting to be a suicide. However, after gathering more evidence, they later determined that Jasmine Camille Kirkland, who was at the home during the shooting was the one who fired the gun at Williams.
Friday, deputies served a warrant charging Jasmine Camille Kirkland with First Degree Murder. She was placed in Alamance County Jail with no bond.


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Make your point with precision!
Sharpie Extra Fine Point Markers feature a precise tip for increased control and accuracy. Available in three bold colors, their quick-drying ink is fade-resistant, water-resistant, and permanent on most surfaces, including many plastic surfaces.
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® Sharpie is a registered trademark of Sanford Corporation.


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niethan is your hero for making this image and getting this theme started.
Buzzsaw's snake lawyer served this image to me and told me I had to post it.
Killgore made this to satisfy his secret inner longings and desires.
This Koobze image looks a lot better after we coated it with acne cream.
This is your typical consumer model throne. If you just want a cheap prop, it's fine. If you want to actually sit like a king, pony up the cash and get yourself a prosumer model. This entry level stuff is more for a duke or baron at best.
Do you wish to know what computers will be doing in the year to come? With a sigh I shall exert the minimal effort it takes to reveal all. Feel free to print out these predictions and share them with your friends via fax.
Chess only has 64 places to stand. BDO has full 3D movement. There's no comparison!
goku hears a wolf howl and joins in for three straight episodes
Airbrush those disgusting wrinkles. Return their flesh to childlike purity.
Photoshop Phriday showcases the tremendous image manipulation talents of the Something Awful Forum Goons. Each week they tackle a new theme, parodying movies, video games, comics, history, and anything else you can think of. If you want in on the action, join us on the Something Awful Forums!
Copyright ©2016 Rich "Lowtax" Kyanka & Something Awful LLC.


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The bone marrow is a spongy material found primarily in the center of long bones and it is where blood cells are produced. Bone marrow is comprised of a variety of cells, which gradually mature to form:
There are a large number of different pathogens, such as bacteria or viruses, which can attack your body. When your immune system fights an infection, it needs to make an antibody that specifically targets the pathogen causing that infection. Each plasma cell can only produce one specific kind of antibody. Individual plasma cells can then divide repeatedly to form copies of themselves, known as clones. This group of clonal plasma cells can produce large amounts of a single kind of antibody to fight a specific infection. There are several thousand different populations of plasma cell clones, which then allow the immune system to make a wide variety of antibodies to target many different kinds of pathogens. Antibodies coat the pathogen that they are built to attack, and thus make it easier for other immune cells to also attack the pathogen.
Multiple myeloma is a cancer of the blood (hematologic cancer) in which one population of clonal (identical) plasma cells starts to reproduce uncontrollably. These cells are known as malignant plasma cells, or myeloma cells. Myeloma cells produce large amounts of one type of antibody, which is known as the monoclonal protein or M-protein. As the number of myeloma cells grows, they begin to overcrowd the bone marrow and prevent normal production of the other blood cell types (red blood cells, platelets, and other white blood cells) in the bone marrow. This also negatively affects the immune system because the bone marrow now predominantly produces only one type of antibody, and can no longer effectively target all pathogens. Thus there is increased risk of infection in patients with multiple myeloma. Anemia results when multiple myeloma prevents the bone marrow from producing enough red blood cells. As the plasma cells continue to multiply, they can invade and damage other organs. The monoclonal protein produced by plasma cells can also damage organs, specifically the kidneys. The acronym "CRAB" is often used to describe symptoms associate with organ damage by multiple myeloma: hyperCalcemia (High levels of calcium in the blood), Renal insufficiency (kidney failure), Anemia (low red blood cell counts), and Bone lesions.
Almost all patients with multiple myeloma evolve from an asymptomatic condition called Monoclonal Gammopathy of Unknown Significance (MGUS). However, since MGUS does not cause any symptoms (asymptomatic), they may not know they have it. People with MGUS have an increased number of clonal plasma cells, but not to the degree seen in multiple myeloma nor do these patients have other symptoms associated with multiple myeloma. However, people with MGUS do have a 1-2% annual risk of developing multiple myeloma or a related blood cancer, such as leukemia or lymphoma. In light of this risk, when someone is first diagnosed with MGUS, it is recommended that blood tests be performed to check for elevated monoclonal protein levels every three months initially.
Some patients may be diagnosed with "smoldering multiple myeloma", which is an early stage of multiple myeloma. Smoldering multiple myeloma meets all the diagnostic criteria for multiple myeloma, but lacks any of the "CRAB" features listed above. The risk of developing symptomatic multiple myeloma is 10% per year for the first 5 years, 3% per year for the next 5 years, and 1.5% per year thereafter. Patients with smoldering myeloma typically do not receive treatment, but are monitored closely for any progression to active myeloma.
Approximately 22,350 people are diagnosed with multiple myeloma a year in the United States. Multiple myeloma comprises approximately 1% of all cancers and comprises about 10% of all "blood cancers", which includes leukemia. The rate of multiple myeloma in blacks is twice that seen in white Americans. Rates appear to be lower in Asians. This disease occurs more commonly in men than in women. The average age at diagnosis is 60 and people under age 40 rarely develop this disease.
At this time, the cause of multiple myeloma is not well established. However, there appear to be several factors which increase the risk of developing multiple myeloma, such as extensive exposure to radiation, chemical resins, organic solvents, pesticides, and herbicides. There is also a herpes virus, Human Herpes Virus 8 (HHV-8), which is thought to be related to the development of multiple myeloma. People with first-degree relatives, such as a mother or brother, who have multiple myeloma, may also be at increased risk for developing the disease. However, a clear genetic mutation related to multiple myeloma has not been discovered.
Unfortunately, because the exact cause of multiple myeloma is unknown, there are no specific guidelines for the prevention of multiple myeloma. Limiting exposure to radiation, chemical resins, organic solvents, pesticides, and herbicides may decrease the risk for developing multiple myeloma.
If you have MGUS or smoldering multiple myeloma, you should see your physician regularly to check for progression to multiple myeloma.
Multiple myeloma is very rare, accounting for only 1% of all cancers diagnosed in the United States, and thus there are no effective screening tests available. However, there are some basic tests which can help with the diagnosis of multiple myeloma. Almost all people with multiple myeloma have monoclonal proteins in their blood or urine, and there are effective tests available to check for them. Other blood tests to check for kidney disease, high calcium levels, and low red blood cell counts (anemia) can also be used to test for the disease. X-rays can be used to detect erosions in bones caused by multiple myeloma.
The increased number of myeloma cells, as well as the high levels of monoclonal protein that they produce, can cause several symptoms in people with multiple myeloma. The symptoms are related either to infiltration of the bone marrow by plasma cells or end-organ damage. Because of advances in routine blood work over the last 20 years, patients are more frequently being diagnosed with asymptomatic disease.
Multiple myeloma increases bone breakdown and decreases formation of new bone, leading to "lytic lesions," or areas where the bone has been "punched out" and looks like holes on the x-ray. Bone pain is the most common presenting symptom, with up to two-thirds of patients having bone pain at diagnosis. The pain is typically in the back or chest, but can occur in the leg or arm bones. It is usually associated with movement and is not commonly present at night, unless the person moves. Multiple myeloma can cause osteoporosis, or generalized weakening of the bone, and weakness at the location of the "punched out" bony lesions. This makes people with multiple myeloma more vulnerable to fractures (broken bones). Often fractures can occur with little or no trauma due to the weakening of the bone. Very commonly, the vertebral bodies (the bones that make up the spine) are affected, leading to "compression fractures." A compression fracture is one where some of the height of the vertebral body is lost and can cause pain or numbness if nerve roots exiting the spinal cord are injured. Multiple myeloma can also cause bone erosions, which occur when small areas of bone are eaten away. On x-ray, erosions can make the bone appear patchy with the areas of bone loss appearing darker. At diagnosis, about 75% of people with multiple myeloma will have evidence of fractures, bone erosions, or osteoporosis on x-ray. Bisphosphonates, a class of medication which strengthens bone, can be used to help improve bone weakness.
Bones have high calcium content and as they are broken down, a large amount of calcium is released into the blood. This condition is also known as hypercalcemia and can occur in up to 30% of people with multiple myeloma. High level of calcium in the blood can cause GI symptoms, such as nausea, vomiting, and constipation. It can affect the urinary system and cause increased urination as well as kidney stones due to the higher calcium concentration in the urine. It can also affect how you feel or act by causing nausea/vomiting, decreased appetite, increased thirst and urination, restlessness and confusion.
About 70% of people with multiple myeloma will have anemia at the time of diagnosis. As the bone marrow becomes overcrowded with myeloma cells, red blood cells cannot be produced in adequate numbers. There are not enough red blood cells in the blood, and this decreases the body's ability to transport oxygen to the tissues and to transport carbon dioxide to the lungs for elimination. Due to this, people with anemia often appear pale and have weakness, fatigue and shortness of breath.
The myeloma cells produce a large amount of monoclonal protein, which can thicken the blood to the point where the blood has problems circulating properly in smaller blood vessels. In general, hyperviscosity is uncommon in multiple myeloma. The most common symptom associated with hyperviscosity syndrome is an increased risk of bleeding. People may have spontaneous bleeding of their gums, nose, or bowel during bowel movements. People may also notice continued bleeding after minor procedures, such as dental work. People may also notice that they bruise easier than they do normally. Symptoms related to the neurological system are also frequently seen in hyperviscosity syndrome. These include changes in vision, such as blurriness or loss of vision, hearing loss, numbness, difficulty with balance, headache, tingling, sleepiness, and even seizures. The thicker blood can also affect the heart and cause symptoms of heart failure, where the heart cannot pump blood well. People with heart failure often have fatigue and difficulty breathing.
The spinal cord communicates with the body through a network of nerves. Nerve roots are large bundles of nerves which conduct signals into and out of the spinal cord. Multiple myeloma can weaken the vertebral bones surrounding the spine, leading to fractures, which in turn can compress the nerve roots. Compression can lead to irritation and inflammation of the nerve roots, which is also known as radiculopathy. These nerves control body movement as well as sensation, thus symptoms of radiculopathy are numbness, tingling, shooting pains, and weakness. The spinal cord, which is protected by the surrounding vertebral bodies, can be compressed by collapsing bone or by the growth of a tumor into the spinal canal. This can occur in 5-10% of patients with multiple myeloma. Compression of the spinal cord is a medical emergency, and immediate medical care is necessary to decompress the cord and prevent permanent damage. Cord compression typically causes severe back pain, leg weakness, urinary retention and/or loss of sensation to the genitals.
Excess proteins can build up and cause irritation to nerves, which can result in a condition called peripheral neuropathy. Peripheral neuropathy typically begins with a tingling and/or numbness in the fingers and toes and can progress to painful sensations and extend into the hands and feet.
Myeloma cell overgrowth in the bone marrow prevents normal plasma cells from producing antibodies. It also prevents adequate numbers of other white blood cells from being formed in the bone marrow. Due to this, people with multiple myeloma are more susceptible to infections, often caused by bacteria such as Streptococcus pneumoniae, which can cause pneumonia, meningitis, and bloodstream infections. Treatments, including steroids and chemotherapy, can further increase one's susceptibility to infection. Infection is one of the most important causes of illness and death in multiple myeloma and should be diagnosed and treated promptly.
A plasmacytoma is a collection of myeloma cells that builds up either in the bone or other tissues. Plasmacytomas can develop in the skin anywhere on the body and may appear as purplish lumps. Reports have shown that about 12% of people can develop plasmacytomas in the ribs. Very rarely, plasmacytomas can develop in the brain.
Kidney failure is a frequent and serious complication of multiple myeloma. Kidney function can be measured by checking the level of a compound called creatinine in the blood. Normally, the kidneys remove creatinine from the body, so high levels of creatinine (detected in a blood test) indicate that the kidneys are not functioning well. About 25-50% of people with multiple myeloma have an increased level of creatinine in their blood, indicating kidney failure. There are many factors that contribute to kidney failure in multiple myeloma. However, the most common is deposition of monoclonal protein (produced by myeloma cells) in the kidney's filtration apparatus. This results in an inability of the kidney to filter appropriately, leading to kidney failure. High blood levels of calcium caused by bone breakdown, use of NSAIDs, certain chemotherapy agents, and bisphosphonates can also cause kidney failure. Caution should be taken when having CT scans, as the "contrast" used in these tests can cause or worsen renal failure in patients with multiple myeloma.
Multiple myeloma cannot be diagnosed with any single test result and your healthcare providers may order a combination of laboratory tests to confirm a diagnosis of myeloma, monitor MGUS or smoldering myeloma, or to monitor the disease's response to treatment. While blood count and chemistry levels are used, there are a few tests that are less common, but often used in myeloma diagnosis and management:
There are a specific set of criteria for the diagnosis of multiple myeloma, to help distinguish it from other blood disorders that have similar characteristics to multiple myeloma, such as MGUS, smoldering myeloma, primary amyloidosis, and metastatic carcinoma. A combination of the tests discussed above may be necessary to make a diagnosis.
For a diagnosis of active (symptomatic) multiple myeloma to be made, all of the following criteria must be met:
If these criteria are not met, a diagnosis of MGUS or smoldering myeloma is considered.
Multiple myeloma is disease that can behave very differently in different individuals. It is critically important to identify those patients at high-risk versus low-risk, and tailor treatment accordingly. There are several factors that can predict how aggressive the multiple myeloma will behave and these are incorporated into staging of the disease.
Staging is a way to give a cancer a sort of "rating" that reflects prognosis and helps guide treatment decisions. Staging for myeloma is different than staging for solid tumors (i.e. breast, lung and colon cancer), which typically uses an I-IV stage rating. There are two staging systems used in multiple myeloma; The Durie-Salmon Criteria and The International Staging System (ISS).
The Durie-Salmon Criteria were initially described in 1975 and incorporate levels of M protein, number of bone lesions, hemoglobin and calcium levels and kidney function. The ISS is a simpler system that incorporates beta-2 microglobulin and albumin levels. The ISS is more commonly used today.
International Staging System (ISS)
Durie-Salmon Criteria
Serum beta2-microglobulin <3.5 mg/L and albumin >3.5 g/dL
All of the following:
Not stage I or III
Not stage I or III
Serum beta2-microglobulin ?5.5 mg/L
One or more of the following:
**Durie-Salmon also classifies the stage as A if the kidney function is normal, or B if there is abnormal kidney function (elevated creatinine).
In addition to the stage, many of the tests discussed above are used to determine prognosis, which is also used to make treatment decisions.
Treatment is not recommended for MGUS, and no intervention (treatment) has been found to delay or prevent MGUS from progressing to myeloma. Patients with asymptomatic or smoldering myeloma (stage I) should be followed closely, without treatment, because research studies have found that treating asymptomatic myeloma does not improve survival. The past decade has seen unprecedented advances in the treatment of symptomatic myeloma, with most patients responding to initial therapy, though curative treatment is still lacking.
There are a number of treatment options for myeloma, including chemotherapy, steroids, targeted therapy and high dose chemotherapy with stem cell transplant. Your oncology team will work with you to determine the best treatment or combination of treatments for your cancer. Below you will find an introduction to the available treatments. Research on the treatment of multiple myeloma has made great strides in recent years. Just 10-15 years ago treatment options for myeloma were limited and now there are several options that can be used to fit each person's unique case. These advances occur because patients participate in clinical trials that help find better treatments. Talk with your oncology team about available clinical trials.
Several clinical trials have shown that in patients who are young (age <65 years) and fit enough, high dose chemotherapy and autologous stem cell transplant (using the patient's own stem cells) is a very good treatment option. This may be used as the first line therapy or after the disease has progressed on other therapies. This treatment is not considered a good option for certain high-risk patients with particular DNA abnormalities (chromosome 13 deletion, chromosome 17 translocation), as this may lead to poorer survival.
There are three phases to stem cell transplant therapy: induction therapy, stem cell transplant and maintenance therapy. In transplant candidates, the goal of the initial chemotherapy – called "induction chemotherapy" - is to kill as many myeloma cells as possible without damaging the stem cells. Patients are given several "rounds" of chemotherapy that typically contains bortezomib combined with dexamethasone and a third agent (thalidomide, lenalidomide, doxorubicine or cyclophosphamide), or lenalidomide and dexamethasone alone.
Following this "induction chemotherapy", patients will undergo a stem cell collection. Stem cells used to be collected from bone marrow, in the operating room. Due to the advances in stem cell collection, they can be taken from the blood, which is done in a photopheresis unit at a hospital using a procedure similar to dialysis. The patient sits in a recliner chair and, using a catheter in the chest or arm, blood is pulled out and passed through a machine that takes out the stem cells and returns the rest of the blood to the patient. These cells are then frozen until the patient is ready to receive them.
The next part of the transplant is typically done in the hospital. The patient is given high doses of chemotherapy to kill as much of the myeloma as possible. This treatment also damages or kills the stem cells in the patient's body. A day or two after completing the chemotherapy, the stem cells are thawed and given back to the patient through a catheter. These cells replace the stem cells that were damaged during the high dose chemotherapy, allowing your body to recover from this chemotherapy. In some institutions, the patient will remain in the hospital during the recovery, while others have an apartment or hotel nearby where patients stay and come to the clinic to be checked every day. Talk to the oncology team about their specific procedure.
After transplant, if remission is achieved, patients may require treatment with "maintenance" chemotherapy. It is not currently clear whether maintenance therapy is needed in all patients and your physician may elect instead for observation without maintenance chemotherapy. This is usually a less intense chemotherapy regimen and its goal is to prolong the period of remission. Preferred maintenance therapy is bortezomib, lenalidomide, or thalidomide.
Some studies are looking at the benefit of a second transplant (called tandem transplant) for patients who do not achieve a full remission after the first transplant. With this therapy, a second transplant is done within six months of the first. Up to half of patients treated with tandem transplants may have a complete response, however this is still being studied. In some cases, allogeneic transplant (stem cells from a donor) may be a treatment option. Allogeneic transplant has significant side effects and the risks and benefits of this therapy need to be discussed with each potential patient (see more below).
Patients older than 65 years or with many multiple other medical problems may not be candidates for stem cell transplant. In other patients, stem cell transplant may be reserved for a future treatment. In those patients, chemotherapy and targeted therapies may be used. There are several regimen options that may include a combination of two or more of these medications:
Some clinicians feel that melphalan therapy should be avoided because it destroys the bone marrow stem cells and carries an increased risk of developing leukemia or other bone marrow disorders, such as myelodysplastic syndrome. After achieving remission, maintenance chemotherapy may be recommended with bortezomib, lenalidomide, or thalidomide.
Almost all patients with multiple myeloma eventually relapse, many within 36 months. Management of relapsed myeloma depends on the initial treatment, length of remission, and persisting toxicities and other medical problems. If the initial therapy resulted in a remission >12 months in duration, that therapy will often be used again to treat the relapse. In general, first relapse is treated with regimens containing bortezomib, while subsequent relapses are treated with lenalidomide-containing regimens. Other agents, which have been recently shown effective in treating relapsed myeloma, include liposomal doxorubicin, carfilzomib, and pomalidomide. In relatively healthy patients who had remission longer than 18 months after transplant, a second stem cell transplant may be considered. Overall, patients who do not respond to initial therapy (especially regimens containing bortezomib) have poor overall prognosis. These patients are excellent candidates for clinical trials to investigate novel therapies, such as vorinostat, panabinostat, daratumumab, and elotuzumab.
Patients with kidney failure at presentation require urgent treatment to improve chances of restoring kidney function. Both bortezomib and lenalidomide have been reported to be effective in reversing kidney damage. Plasmapheresis, a process which separates myeloma cells from the blood, has not been shown to be beneficial.
When there is evidence or suspicion of spinal cord compression, dexamethasone should be started immediately followed by urgent imaging of the spine. A neurosurgeon and/or radiation oncologist should be consulted to consider surgical decompression of the spine or radiation therapy to the spine.
Patients experiencing bone pain due to involvement of myeloma may be treated with low-dose radiation (10-30 Gy) to the bones to relieve pain, improving quality of life. If myeloma involves the bones in the spine (the vertebrae) and a vertebral compression fracture occurs, vertebroplasty or kyphoplasty is recommended. Both procedures involve injecting bone cement into the vertebral body; kyphoplasty also uses a balloon to restore normal height of the bone.
Bisphosphonates are commonly used in patients with myeloma to strengthen bones, prevent fractures and lower calcium levels. Bisphosphonates (pamidronate, zoledronate) inhibit bone breakdown and promote formation of new bone, thus opposing the effects of multiple myeloma on bones. Common side effects of oral bisphosphonates include nausea and esophageal inflammation and erosion, which can be prevented by remaining upright for 30-60 minutes after taking the medication. Intravenous (IV) bisphosphonates often cause a flu-like syndrome the first time the medication is received. Long-term use of bisphosphonates is associated with a small risk of osteonecrosis of the jaw (death of the jaw bone), atrial fibrillation, unusual fractures, and esophageal cancer. Usually the benefits of bisphosphonates outweigh the risks, but it is important to discuss risks and benefits as they pertain specifically to you. In addition, bone health can be improved using the medication denosumab, which prevents further bone damage from cancer cells.
Patients with a solitary plasmacytoma (a solid tumor made of myeloma cells) are best treated with radiation therapy as initial (and potentially curative) treatment. Sometimes, surgery is needed after radiation therapy.
Myeloma increases one's risk of developing a blood clot in the legs, known as a deep vein thrombosis (DVT). The risk of developing a DVT is even further increased when taking thalidomide or lenalidomide. Fortunately, DVT only happens in 1-3% of people on thalidomide. However, when used in combination with dexamethasone, this can increase to 10-15%, and if used in combination with dexamethasone and doxorubicin, (another chemotherapeutic drug), this number can increase to 25%. DVT in the leg is concerning because the blood clot in the leg can travel to the lungs, causing a serious condition called pulmonary embolus. A pulmonary embolus can cause cough, chest pain, shortness of breath, and even death. Due to the risk of DVT and pulmonary embolism, all patients taking lenalidomide with dexamethasone or any thalidomide-containing therapy should receive anticoagulation (blood thinners) to prevent formation of a blood clot. Thalidomide and lenalidomide also cause severe life-threatening birth defects. You should not become pregnant or father a child while taking these medications. Bortezomib can increase one's risk of developing herpes zoster (shingles), so a shingles vaccine is recommended prior to bortezomib therapy. Other side effects of chemotherapy agents include low blood counts, fatigue, constipation, diarrhea and neuropathy (nerve damage, usually manifesting as numbness in the fingers and toes).
There are two types of transplants: autologous transplants, where the stem cells to be transplanted come from the person with multiple myeloma, and allogeneic transplants, where stem cells are harvested from a donor who has been matched with the person with multiple myeloma. The role of allogeneic transplant in myeloma is controversial and still being studied.
One theoretical advantage of allogeneic over autologous transplant is that even after induction chemotherapy, there are often still malignant cells in the blood. Inevitably, during harvesting of stem cells, some of the remaining malignant cells are accidentally collected. Allogeneic cells come from a donor with no malignant cells; hence the collected stem cells contain no cancer cells.
Allogeneic cells also cause graft versus host phenomenon, which can be good and bad. The grafted stem cells form the new immune system for the person receiving the transplant. Unfortunately, this new immune system may perceive the host tissues (the organs of the patient who received the transplant) as foreign and attack them. Typically, the liver, gastrointestinal tract, and skin are most severely affected. However, the new immune system can be used for good since it recognizes the myeloma cells as foreign and can attack any myeloma cells that are left. Graft versus host disease can cause organ failure, and immunosuppression to control graft versus host disease can increase the risk of infection. Hence, there has to be a careful balance when suppressing the new immune system to protect organs, but also allowing the new immune system to destroy any left over myeloma cells.
Another complication of allogeneic transplants is that the donor tissue must be matched to the recipient. Sometimes family members can be donors, but in the event that is not possible, the national registry of bone marrow donors can be searched for a match. Mortality from allogeneic transplant can be as high as 10-20%. Currently, allogeneic transplant as initial therapy should only be considered in the context of a clinical trial.
There is continued investigation of nonmyeloablative transplants ("mini-transplants"), where low doses of chemotherapy are used after stem cell harvest to kill myeloma cells prior to allogeneic transplant. In nonmyeloablative transplants, the goal is to decrease toxicity, but preserve the beneficial graft-versus-myeloma effect. Like other allogeneic transplants, mini-transplants are only recommended when used in the setting of a clinical trial.
Follow up appointments to monitor for recurrence are very important in people with multiple myeloma given the high rate of relapse. Generally, after completion of treatment your doctor may ask you to follow up every one to three months. The follow up visit usually entails a physical exam, x-rays, blood tests and urine tests. X-rays are used to check for bone disease and blood and urine tests are used to check for the level of monoclonal proteins. Blood tests to check kidney function, calcium levels, and cell counts are also done routinely. Repeated bone marrow biopsies may also be needed to check for myeloma cells in the bone marrow.
Multiple myeloma is an area of active research and numerous clinical trials. Currently, clinical trials are investigating new therapeutic agents, new combinations of existing treatments, and different sequencing or timing of treatments. Many promising agents are in the pipeline, some with completely novel mechanisms of action. Some agents under investigation include vorinostat and panabinostat (histone deacetylase inhibitors), daratumumab (a human anti-CD38 monoclonal antibody), anti-cyclin dependent kinase inihibitors, and elotuzumab (an anti-CS1 monoclonal antibody), aplidin, marizomib, and ixazomib. You can learn more about ongoing clinical trials and find those that may be right for you using the OncoLink Clinical Trials Matching Service or online at clinicaltrials.gov.
OncoLink is designed for educational purposes only and is not engaged in rendering medical advice or professional services. The information provided through OncoLink should not be used for diagnosing or treating a health problem or a disease. It is not a substitute for professional care. If you have or suspect you may have a health problem or have questions or concerns about the medication that you have been prescribed, you should consult your health care provider.
Information Provided By: www.oncolink.org | © 2016 Trustees of The University of Pennsylvania


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At Innkeeper's Lodge you'll find accommodation with comfort and character in equal measure, and everything needed for a relaxing stay, from easy check-in and free parking to complimentary breakfast an...More about Innkeeper's Lodge Old Windsor
Premier Inn Heathrow Airport Terminal 5 is so close to the planes you're practically on the runway. If you're just passing through you'll find all you need here - spacious rooms, extra-comfy beds, a s...More about Premier Inn Heathrow Airport Terminal 5
This elegant Georgian manor is set amid beautiful gardens and has been skilfully restored. Character public rooms are pleasing and include a number of air-conditioned conference rooms and an elegant r...More about Taplow House Hotel
A Victorian property situated in a quiet residential area of Windsor, just 200 metres from the River Thames and a 10 minute walk along the riverside into the centre. A warm welcome can be expected and...More about 76 Duke Street B&B
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The Lancaster Hotel & Spa is conveniently located within the grounds of Brunel University London and is the ideal location for visiting the university or for professionals on business. The complex has...More about Lancaster Hotel & Spa
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OI009: Shell Shock!
Revision as of 02:59, March 12, 2013 by Joshuabassett0 (Talk | contribs)
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Episode Plot
Aboard Lapras, the group follows a news crew to an uninhabited island, where a scientific expedition is underway after the discovery of a fossilized Kabuto. A series of natural disasters place our heroes in mortal danger, with only the power of their Pokémon to help them. What is the secret of the Kabuto, and who wants that secret to remain hidden?
- This is the first time we see Nurse Joy in a different outfit other than her nurses uniform.
- Despite having already encountered Kabutos in Kanto, neither Ash or Misty ever mentions this. They even react with shock at the idea of fossilized Kabutos.
- Dexter refers to Kabuto as being "believed to be extinct", despite being present when Ash previously encountered living Kabutos.
- Apparently Professor Oak does not share the information collected from his trainer's Pokedexs, as everyone believed Kabuto to be still extinct. Had he done so, the entire expedition would have been pointless.
- The "Who's that Pokémon?" in this episode is ponyta.
- The idea of an island made of fossils isn't far fetched, no pun intended, the coral reefs take 10,000 years to form. Coral atoll, coral islands, can take up to 30 million years to form. Since Kabutos went extinct 300 million years ago it makes sense that a large island has formed from the fossils that were there.
- It seems from previous episodes and this episode that ancient pokemon appear to have some sort of hibernation ability on a level of stasis where their bodies don't decay or degrade in any way even for millions of years. However it appears inorder to avoid damage the ancient pokemon hibernate in caves for protection and the fact that caves climate stay the same even for millions of years unless geological activity or humans change the cave.
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Please help the Pokémon Wiki by expanding it.
| This article has an incomplete plot or synopsis.
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Threats against schools are being taken very seriously right now, and law enforcement is taking the side of caution. 11 News talked with the El Paso County Sheriff's Office who said they are seeing threats and rumors happen all over the country.
Friday, the Sheriff's Office said they had to step up patrols around the entire county because they said they've had several mentions and rumors about things happening on the day 12/21/12.
In Cañon City, a Harrison Middle School student sent a text message to two other students at two separate Canon City Schools threatening school violence at Harrison School at the close of school today. The violence described a school shooting.
A 13 year-old boy of Cañon City was taken into custody for investigation of charges related to Interference with Staff, Faculty or Students of Educational Institutions. He was later released to his parents.
Earlier this week in El Paso County, deputies were forced to respond with increased patrols to a rumor which turned out to be just that, a rumor.
"But regardless of that, and despite that conclusion that we came to, we did in fact deploy additional resources and school districts throughout the county," El Paso County Sheriff's Lt Jeff Kramer said.
"It was worth at least investigating so yeah, I think it's pretty worth their time to do it, it's just a shame they have to do it," a Springs dad said.
Over the past week, we've seen and heard these instances happen across the country, and those we talked to say right now, there's not a better option for law enforcement
"I think it's smart for the time being for them to adequately stock our school for safety," a local mom told us.
"It's annoying because you're like we're here to learn not to be in danger of something happening," one high schooler said.
In Pueblo, a middle school student claimed to find a note about a bomb inside the school. He later admitted to writing the note and is now in Pueblo's Youth Corrections facing felony charges.
"I think it's unfortunate, what it does, it puts tremendous stress on our local law enforcement," a Springs parent said.
That teen is facing charges of false report of explosives, weapons, or harmful substances; a class 6 felony.
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Quality CareFind out why Mayo Clinic is the right place for your health care. Make an appointment.
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Our general interest e-newsletter keeps you up to date on a wide variety of health topics.
In terms of your overall health, it makes little difference when you stop taking the pill. When you finally do stop the pill, you can expect some bleeding, which may change the rhythm of your menstrual cycle. But you can stop at any time.
Taking the nonactive pills doesn't put you at higher risk of unintended pregnancy. If you're taking your birth control pills exactly as directed, they're 98 to 99 percent effective at preventing pregnancy.
If, however, you've missed a pill — or several pills — during a cycle, you might be at higher risk of unintended pregnancy during that cycle. To be safe, use a backup form of contraception, such as a condom.
Many women think so. But studies have shown that the effect of the birth control pill on weight is small — if it exists at all. Instead, you may be retaining more fluid, which can make you feel as if you've put on weight, particularly in your breasts, hips and thighs. The estrogen in birth control pills does affect fat (adipose) cells, making them larger but not more numerous.
Scientific evidence suggests using birth control pills for longer periods of time increases your risk of some cancers, such as cervical cancer and liver cancer, but it also decreases your risk of other types of cancer, including ovarian cancer and endometrial cancer.
The effect of birth control pills on breast cancer risk isn't quite clear. While some studies have shown a link between pill use and breast cancer, more-recent studies do not show an increased risk of breast cancer with the pill. If you're concerned about your risk of breast cancer, talk with your health care provider about whether the pill is the right contraceptive for you.
Birth control pills can affect cholesterol levels. How much of an effect depends on the type of pill you're taking and what concentration of estrogen or progestin it contains. Birth control pills with more estrogen can have a slightly beneficial overall effect on your blood lipid levels. In general, though, the changes aren't significant and don't affect your overall health.
Birth control pills may slightly increase blood pressure. If you take birth control pills, have your blood pressure checked regularly. If you already have high blood pressure, talk with your doctor about whether you should consider an alternative form of birth control.
Although women older than age 35 used to be told to stop taking birth control pills, these limits no longer apply to healthy, nonsmoking women. However, birth control pills aren't recommended for women older than age 35 who smoke because of the risk of cardiovascular disease. If you're 35 or older and you smoke, you need to quit smoking before you can safely continue using birth control pills.
The effects of antibiotics on birth control pills may be overstated — except in the case of one antibiotic, rifampin. Studies clearly show that rifampin decreases the effectiveness of birth control pills in preventing ovulation. However, rifampin isn't used widely today.
Mayo Clinic is a not-for-profit organization. Proceeds from website advertising help support our mission. Mayo Clinic does not endorse non-Mayo products and services.
Check out these best-sellers and special offers on books and newsletters from Mayo Clinic.
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We comply with the HONcode standard for trustworthy health information: verify here.


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I knew I'd seen this somewhere, and I meant to go looking for it again. In my spare time. Ahem. Fortunately, I just stumbled upon it. The File ID Assistant.
If you're using the digital component of the MRIN Filing System, and you're a Legacy user, there's a quick way to find your next MRIN or your next MRIN-extension. When you go to put a number in the Source Citation Detail Box, click on the magnifier next to the File ID box.
It will bring up the File ID Assistant box, showing a list of all File ID numbers already used. In this example, I'm looking for the next extension for MRIN 107.
Since I've already taken note of what MRIN number I'm presently working on, I type in the MRIN (in the form I actually use the number for source citation file IDs, which is 0107) and click Refresh. It will then show me what extensions are already used. I can click on Select +1 and it will automatically insert the next MRIN+extension in the File ID box. I add the same number to my digital document and move it to my digital Source Library. If I need to use that number for other people being sourced from that same document, it can be done here through the Select button, or simple copy and paste.
If you're renumbering MRINs as you go, you could also be looking for the next one to use. If you don't type in anything but just click Refresh List, at the bottom of the list it will show you the last one used. Here it's 5047.
This works the same over at the Master Source File ID location.
You can also filter your list to show only certain numbers. Source Citation file IDs when you're working with MRINs and Master Source file IDs when you're working with Master Sources, obviously. Maybe both, depending on how you use numbering.
I had been using a more awkward method of keeping several windows open at once, clicking back and forth between my database, the document I was sourcing and my Source Library, looking for "next-numbers." This is much easier. (Yes, I did too read my Legacy User Guide, but it was a really long time ago.)


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From Edmunds.com
Different drivers have different priorities when evaluating road trip vehicles. For some, a roomy and comfortable cabin is important; all the better for hauling the gaggle of friends — or the spouse and kids — who'll be coming along for the ride. Drivers with an enthusiast bent are more likely to favor a vehicle sporty enough to make the journey a thoroughly engaging one. And frugal-minded folks might value fuel efficiency most of all.
We asked our Edmunds editors to cull their road trip favorites. Here are their picks, listed in alphabetical order.
Copyright Edmunds.com, Inc. All rights reserved. First published on www.edmunds.com and excerpted with permission. http://www.edmunds.com/car-reviews/top-10/top-10-best-road-trip-vehicles-for-2011.html


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Broncos QB Peyton Manning, who completed 28-of-43 passes (65.1%) for 290 yards with three touchdowns and two interceptions (88.3 rtg.) against Baltimore, tied Brett Favre for the second-most completions (481) in NFL postseason history and tied Dan Marino for the fourth-most passing touchdowns (32) in playoff annals.
Click Here to access the online Public Inspection File
Viewers with disabilities can get assistance accessing this station's FCC Public Inspection File by contacting the station with the information listed below. Questions or concerns relating to the accessibility of the FCC's online public file system should be directed to the FCC at 888-225-5322, 888-835-5322 (TTY), or firstname.lastname@example.com.


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Nursing staff responsible for caring for individuals with diabetes. This is a high-level course primarily designed for Registered Nurses. Although other professions are welcome, the course material requires participants to have a strong knowledge of nursing, human anatomy and physiology and capability to understand the diabetic pathology presented.
To see more detailed information and register:
October 2, 2013 - 9:00 AM - 4:00
Murray Developmental Center
Conference Room #3
1535 West McCord Street
Centralia, Illinois 62801
(618) 532-1811
Parking: Lot around building. Enter main gate and watch for signs to Administration building for directions to Conference Room #3.
DM Training Course Offerings - Select a training date for location and other training course information when available.
No events for May


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The Power of Independent Thinking
Bush, Obama, and Presidential Power
Recorded: Wednesday, January 7, 2009
Part 1 |
Part 2
Part 3
Was George W. Bush the worst president ever? Ivan Eland examines Bushs presidency and those of his predecessors to determine if their policies promoted peace, prosperity, and liberty while upholding the Constitution they swore to protect.
Experts: Ivan Eland, Ron Paul, Richard ShenkmanType: Independent Institute EventIssues: Banking and Finance, Bureaucracy and Government, Civil Liberties/ Human Rights, Constitutional Law, Culture/ Society, Defense and Foreign Policy, Democracy, Economic History and Development (U.S.), Economic Policy, Freedom, Government Power, History (U.S), Nationalism, Political Ideology and Philosophy, Politics, Privacy, Terrorism and National Crises
Private Solutions for Reducing Road Congestion, Fuel Costs, Travel Time, and Waste
Recorded: Thursday, September 28, 2006
Part 1 |
Part 2
Part 3
Part 4
Part 5
Part 6
Part 7
Part 8
Part 9
Part 10
Congestion is not a fact of life, declared Mr. Mineta, We need a new approach, and we need it now. Such an approach is presented in the new Independent Institute book, Street Smart: Competition, Entrepreneurship and the Future of Roads.
Experts: Daniel B. Klein, Gabriel Roth, Alexander T. TabarrokType: Independent Institute EventIssues: Privatization, Transportation


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September 18, 2011
Josh Helmholdt
Rivals.com Football Recruiting
Cameron Burrows and some of the top junior prospects in Ohio this weekend and they did not disappoint. Here's a closer look at the top performers. ...More... To continue reading this article you must be a member. Sign Up Now!
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STMicroelectronics Makes Leading-Edge MEMS Technology Available for Prototyping through CMPInitiative sets to advance new application developments in motion sensing
ST's long-term success in MEMS (Micro-Electro-Mechanical Systems) sensors has drawn upon Company-developed industry-leading manufacturing processes. The 0.8-micron, surface micro-machining THELMA (Thick Epitaxial Layer for Micro-gyroscopes and Accelerometers) process combines variably thick and thin poly-silicon layers for structures and interconnections. This enables the integration of linear and angular mechanical elements in a single chip, delivering significant cost and size benefits to customers.
The CMP multi-project wafer service allows organizations to obtain small quantities--typically from a few dozens to a few thousand units--of advanced ICs manufactured using the same process technologies as would be used on much higher-volume products. The THELMA process design rules and design kits are now available for universities and microelectronics companies and the first requests are already being answered.The introduction of ST's MEMS manufacturing process in CMP's catalogue builds on the successful collaboration that has allowed universities and design firms to access ST's semiconductor manufacturing processes from the 130nm CMOS, introduced in 2003, up to the 28nm FD-SOI technology, released for prototyping in late 2012, which enables the efficient design of next-generation mobile devices that simultaneously require high performance and low power consumption.
"The small-scale availability of our industry-leading MEMS process alongside CMOS technologies including the game-changing FD-SOI, complemented with CMP's advanced service capabilities, offers unprecedented access to state-of-the-art in chip manufacturing for start-ups and R&D labs looking to design intelligent sensor systems," said Benedetto Vigna, Executive Vice President, General Manager, Analog, MEMS & Sensors Group, STMicroelectronics. "With leading-edge industrialized processes at their fingertips, innovators can now concentrate on developing new products rather than investing time and resources in developing technologies."
"Anticipating huge development in MEMS, CMP was the first silicon brokerage service in the world to offer MEMS technologies as early as in 1995," said Bernard Courtois, Director of CMP. "Today, CMP is expanding the very successful ST partnership to the THELMA process, offering both the CMOS part and the MEMS part from a single manufacturer. Going beyond inertial sensors, pressure sensors, microphones, e-compasses etc., the ST-CMP partnership will allow CMP customers to move towards complex, embedded systems, addressing more and more societal needs, as components of the Internet of Things."
Perspectives on Smart Systems for the Internet of Things will be presented later today by ST's Benedetto Vigna in his opening keynote address at the DATE (Design, Automation & test in Europe) event in Grenoble, France. (http://www.date-conference.com/).About STMicroelectronics
ST is a global leader in the semiconductor market serving customers across the spectrum of sense and power and automotive products and embedded processing solutions. From energy management and savings to trust and data security, from healthcare and wellness to smart consumer devices, in the home, car and office, at work and at play, ST is found everywhere microelectronics make a positive and innovative contribution to people's life. By getting more from technology to get more from life, ST stands for life.augmented.
In 2012, the Company's net revenues were $8.49 billion. Further information on ST can be found at www.st.com.About CMP
CMP is a broker in ICs and MEMS for prototyping and low volume production. Circuits are fabricated for Universities, Research Laboratories and Industrial Companies. Advanced industrial technologies are available in CMOS, BiCMOS, SiGe BiCMOS, High Voltage, FD-SOI down to 20nm, pHEMT GaAs, and MEMS etc. CMP distributes and supports several CAD software tools for both Industrial Companies and Universities. Since 1981, more than 1000 Institutions from 70 countries have been served, more than 6,000 projects have been prototyped through 700 runs, and 60 different technologies have been interfaced. For more information, visit: http://cmp.imag.fr
Bernard Courtois
+33 4 76 57 46 15


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Colorado ski resorts say they learned a lesson last season when snow levels fell to half of normal.
Arapahoe Basin built a 700-foot snow fence at the top of the ski area to capture snow that groomers can use to cover thin spots.
Keystone has five new fan snow guns and 30 low-energy stick guns that will help reduce energy and water use, making it last longer.
According to the Denver Post, ski resorts are worried about a continuing drought that has reduced creek levels.
Copyright 2016 Associated Press. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.
KKTV firmly believes in freedom of speech for all and we are happy to provide this forum for the community to share opinions and facts. We ask that commenters keep it clean, keep it truthful, stay on topic and be responsible. Comments left here do not necessarily represent the viewpoint of KKTV 11 News.
If you believe that any of the comments on our site are inappropriate or offensive, please tell us by clicking "Report Abuse" and answering the questions that follow. We will review any reported comments promptly.powered by Disqus
Click Here to access the online Public Inspection File
Viewers with disabilities can get assistance accessing this station's FCC Public Inspection File by contacting the station with the information listed below. Questions or concerns relating to the accessibility of the FCC's online public file system should be directed to the FCC at 888-225-5322, 888-835-5322 (TTY), or firstname.lastname@example.com.


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Knock Boxes
Espresso Machine Knock Boxes
Knock! Knock! Who's there? It is no joke…Knock boxes are handy to have and easy to use. Turn your portafilter upside down and give it a good smack against the inner bar or side of the box to loosen the spent espresso puck. Keep the mess in the box, and the flavor in the cup. We stock many knock box designs and sizes to choose from the most utilitarian plastic container to hand crafted maple masterpieces.
Learn More about Knock Boxes
JoeFrex Basic Knock BoxSmall, but imminently sturdy, the JoeFrex Basic Knock Box comes in an unassuming gray or an in-your-face red. Made of space age plastic, the silicone covered knock bar is easy to remove and both pieces can be tossed in the dishwasher for fast cleaning. Unlike the rest, this item's knock bar is shock absorbing and made of food safe silicone. The knock box can take plenty of mucky espresso pucks and it will stay in place with a rubber buffer on the bottom. Learn More$22.90
Out of stock