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|By PR Newswire
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|January 29, 2014 08:05 AM EST
SAN DIEGO, Jan. 29, 2014 /PRNewswire/ -- Organovo Holdings, Inc. (NYSE MKT: ONVO) ("Organovo"), a three-dimensional biology company focused on delivering breakthrough 3D bioprinting technology, today announced that it has performed its first 3D Liver tissue delivery.
The achievement marks the delivery of Organovo's 3D Liver tissue to a laboratory outside of the company to a key opinion leader (KOL) for experimentation, and marks the achievement of a milestone along the pathway to commercial launch of its 3D liver tissue product. Organovo achieved the milestone ahead of its April 2014 target date. Key opinion leaders are generally experts, in this case top research scientists, in a particular field whose opinions and publications will influence practice. Organovo expects KOLs to make recommendations on improvements to the tissue before launch and to influence peers through their reporting of their research results at conferences and through peer reviewed publications.
"This is an important milestone for Organovo R&D," said Organovo Chief Technology Officer and Executive Vice President of Research and Development Dr. Sharon Presnell. "In developing these tissues, we have gone through a careful set of research studies involving many individual tissues, and greatly increased our ability to produce them. By the end of January, we expect to have bioprinted nearly four hundred 3D Liver tissues during the month."
Organovo also introduced updated guidance on the timing of its product launch. Organovo had planned to launch its 3D Liver tissue product by the end of December 2014. It now expects to commence the commercial launch and start generating revenue through a services model prior to December 2014. "As pharmaceutical and biotechnology companies move to continue to outsource their R&D efforts," explained Keith Murphy, Organovo's chief executive officer, "our ability to deliver a service offering in addition to products will be critical to meet their needs and to enter the $7B preclinical research services market." The company anticipates that preclinical toxicology testing services can command prices in the high tens of thousands of dollars per compound for standard screening for liver alone.
Organovo's 3D Liver tissues exhibit several key features that remain stable over time:
- Tissue-like cellular density;
- Multi-layered architecture with multiple cell types positioned relative to one another, reaching up to 500 microns thickness, with tissues comprised of up to 20 cell layers;
- Albumin production 5-9 times greater than matched 2D controls, suggesting superior functionality;
- Stable albumin production for over 40 days, fibrinogen and transferrin production, and inducible cytochrome P450 enzymatic activities, including CYP 1A2 and CYP 3A4;
- Cholesterol biosynthesis, which has been demonstrated for the first time in a multi-cellular 3D human liver system in vitro;
- Evidence of the formation of tight junctions in the liver tissues, demonstrated by cadherin and claudin staining by day 3 of tissue formation; and
- Demonstration of appropriate response to hepatotoxic insults from acetaminophen, acetaminophen in combination with ethanol, and diclofenac.
Organovo plans to release additional data in 2014 on its 3D Kidney tissues and breast cancer tissues now in development. In December, Organovo demonstrated that its NovoGen bioprinted breast cancer tissues retain compartmentalized structures with interaction between stromal and cancer cells, along with formation of endothelial networks and differentiation of adipocytes. NovoGen 3D bioprinted constructs were demonstrated to be less susceptible to tamoxifen-induced toxicity than isolated 2D cancer cells when treated with the same dose of tamoxifen for the same duration, highlighting the potential utility of this model in identifying superior drugs with greater toxicity against complex, multicellular 3D tumor models.
Organovo also reminded investors of the continued availability of Organovo's December 5, 2013 online presentation. Organovo's Chairman and Chief Executive Officer, Keith Murphy, presented in a live interactive online forum that was a recorded event. The online content that can be accessed consists of a 30 min presentation as well as the text of a Q&A session that followed.
LINK: www.retailinvestorconferences.com > click on red "register / watch event now" button
The Company also reminded investors of its guidance to investors regarding "Short and Distort" articles.
About Organovo Holdings, Inc.
Organovo designs and creates functional, three-dimensional human tissues for medical research and therapeutic applications. The Company is collaborating with pharmaceutical and academic partners to develop human biological disease models in three dimensions. These 3D human tissues have the potential to accelerate the drug discovery process, enabling treatments to be developed faster and at lower cost. In addition to numerous scientific publications, the Company's technology has been featured in The Wall Street Journal, Time Magazine, and The Economist. Organovo is changing the shape of medical research and practice. Learn more at www.organovo.com.
Safe Harbor State
Any statements contained in this press release that do not describe historical facts may constitute forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995. Any forward-looking statements contained herein are based on current expectations, but are subject to a number of risks and uncertainties. The factors that could cause actual future results to differ materially from current expectations include, but are not limited to, risks and uncertainties relating to the Company's ability to develop, market and sell products based on its technology; the expected benefits and efficacy of the Company's products and technology; the timing of commercial launch and the market acceptance and potential for the Company's products, and the risks related to the Company's business, research, product development, regulatory approval, marketing and distribution plans and strategies. These and other factors are identified and described in more detail in our filings with the SEC, including the prospectus supplement that we filed with the SEC on November 27, 2013 and the transition report on Form 10-KT for the period ended March 31, 2013 that we filed with the SEC on May 24, 2013 and our other filings with the Securities and Exchange Commission. You should not place undue reliance on these forward-looking statements, which speak only as of the date that they were made. These cautionary statements should be considered with any written or oral forward-looking statements that we may issue in the future. Except as required by applicable law, including the securities laws of the United States, we do not intend to update any of the forward-looking statements to conform these statements to reflect actual results, later events or circumstances or to reflect the occurrence of unanticipated events.
SOURCE Organovo Holdings, Inc.
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Record number of Clemson players picked in the 2016 NFL draftLive 5 News CharlestonMay 01 04:53 AM
Several Clemson Tigers were selected for the National Football League during the 2016 draft.
9 selections in historic 2016 NFL Draft for Clem... - WYFF 4 Greenville
Clemson football could make history in this year... - The Rock Hill Herald
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Lee denounces Clemson's lack of aggressive play after 11-2 loss to FSUThe Post and CourierMay 01 02:53 PM
CLEMSON – It wasn't so much that Clemson lost. It was how the Tigers lost, in Monte Lee's eyes.
Rashan Gary Received Racist Voicemail From Man A... - Bleacher Report
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GT Tops No. 23 Clemson 7-5 - Toledo News Now
9 Clemson players drafted by NFL teamsToledo News NowMay 02 03:09 AM
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Clemson beats 3rd-ranked Florida State - WIS News 10 Columbia
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10 at 10: Venables displeased with Clemson defen... - The Post and Courier
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CLEMSON — Seth Beer and Pat Krall are unquestionably Clemson's most valuable player and pitcher this season.
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Beer, Krall lead Tigers to series clincher over SeminolesThe Post and CourierMay 02 04:52 PM
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|By Business Wire
Article Rating:
|December 10, 2012 03:00 PM EST
AppTap (http://www.apptap.com), the leading mobile app discovery and app advertising network for iPhone, iPad and Android apps, today announced a partnership with Future PLC (http://www.futureplc.com/) an international media group and leading digital publisher. The partnership brings AppTap's contextual app recommendations and advertising platform to readers on Future's top media properties, including TechRadar, ComputerAndVideoGames.com (CVG), T3, PC Gamer, Total Film, and more.
Consumers live in a world in which mobile apps are the primary way they access information, products and services central to their lives. Yet, with over a million apps available across Android and iOS, finding apps that meet an individual's interests is difficult and overwhelming. App developers, too, are struggling to find the right users for their apps. AppTap solves the discovery problem for consumers and app developers, bringing app discovery to consumers where they already spend time online, and using context to target users with app recommendations relevant to their interests in a dynamic, real time environment.
"Apps are central to all aspects of our lives, yet the app store and search paradigm for app discovery is not enough to help consumers and app developers navigate this increasingly crowded space," said Matt Callaway, CEO, AppTap. "Our partnership with Future is another step in our mission to bring app discovery to users everywhere, and to use context and other critical data to deliver the right app, to the right user, at the right time."
AppTap's platform enables publishers, such as Future, to improve their mobile product experience, grow engagement and increase mobile revenue by adding contextual app recommendations, social discovery and app search to their properties. This benefits consumers as they can now easily discover apps relevant to their interests right on their favorite sites, and it helps app developers by targeting promotion of their apps to consumers that are likely to be highly engaged app users.
"As our mobile audience continues to grow, we're very focused on ensuring we're delivering the product experience our users want and optimizing our revenue opportunity," said Nick King, Digital Commercial Director, Future plc. "AppTap's combination of app discovery and app advertising in a single platform strikes the perfect balance of enhancing our product experience while also generating revenue."
AppTap is showcasing its mobile app discovery and advertising platform at APPNATION December 11-12, 2012 in San Francisco. Visit AppTap at Booth B2, Moscone West, or attend their presentation at the APPNATION Developer Bootcamp on December 12 at 10:30 am.
About AppTap
AppTap is a contextual app recommendations and advertising platform for iOS and Android. The company helps consumers find apps relevant to their interests through contextual app recommendations within content on leading media sites. App developers promote their apps on the AppTap Network through targeted sponsored placements. Media companies, carriers and other partners use AppTap to boost user engagement and mobile revenue. Based in Reston, VA, AppTap is funded by Syncom Venture Partners and New Atlantic Ventures. More information can be found at http://www.apptap.com or follow AppTap on Twitter at @apptap.
About Future PLC
Future plc is an international media group and leading digital publisher, listed on the London Stock Exchange (symbol: FUTR). Founded in 1985 with one magazine, today we have operations in the UK, US and Australia creating 200 special-interest publications, apps, websites and events. We hold market-leading positions in Games, Film, Music, Technology, Cycling, Automotive and Crafts. Our most well-known products include T3, Total Film, Classic Rock and Official Xbox Magazine. Our websites include gamesradar.com, bikeradar.com, musicradar.com and techradar.com (the UK's number one consumer technology website). Future sells 2.2 million magazines each month; we attract more than 50 million monthly unique visitors to our websites; and we deliver over 100 digital editions and bespoke apps on tablet. Future exports or syndicates publications to 89 countries, making us the UK's number one exporter and licensor of magazine content. Future was named Consumer Digital Publisher of the Year for the second year running at the Association of Online Publishers Awards 2012 and PPA Digital Consumer Publisher of the Year 2012.
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You deployed your app with the Bluemix PaaS and it's gaining some serious traction, so it's time to make some tweaks. Did you design your application in a way that it can scale in the cloud? Were you even thinking about the cloud when you built the app? If not, chances are your app is going to break. Check out this webcast to learn various techniques for designing applications that will scale successfully in Bluemix, for the confidence you need to take your apps to the next level and beyond.
Apr. 29, 2016 11:15 AM EDT Reads: 1,421
Manufacturers are embracing the Industrial Internet the same way consumers are leveraging Fitbits – to improve overall health and wellness. Both can provide consistent measurement, visibility, and suggest performance improvements customized to help reach goals. Fitbit users can view real-time data and make adjustments to increase their activity. In his session at @ThingsExpo, Mark Bernardo Professional Services Leader, Americas, at GE Digital, will discuss how leveraging the Industrial Interne...
Apr. 29, 2016 10:00 AM EDT Reads: 1,116
Whether your IoT service is connecting cars, homes, appliances, wearable, cameras or other devices, one question hangs in the balance – how do you actually make money from this service? The ability to turn your IoT service into profit requires the ability to create a monetization strategy that is flexible, scalable and working for you in real-time. It must be a transparent, smoothly implemented strategy that all stakeholders – from customers to the board – will be able to understand and comprehe...
Apr. 29, 2016 09:30 AM EDT Reads: 998
Increasing IoT connectivity is forcing enterprises to find elegant solutions to organize and visualize all incoming data from these connected devices with re-configurable dashboard widgets to effectively allow rapid decision-making for everything from immediate actions in tactical situations to strategic analysis and reporting. In his session at 18th Cloud Expo, Shikhir Singh, Senior Developer Relations Manager at Sencha, will discuss how to create HTML5 dashboards that interact with IoT devic...
Apr. 29, 2016 09:00 AM EDT Reads: 850


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ALL TRANSPORTATION METHODS INVOLVE some risk, but corporate/executive business jets enjoy a stellar safety record, with only one fatal accident since 2007. That's according to statistics on U.S.-registered aircraft from Robert E. Breiling Associates, an aviation-safety research firm.
October 1, 2010
October 1, 2010
One of the big advantages bizav has over airline travel is your ability to get more done by hitting multiple stops in a single day. Now, thanks to in-flight Internet services such as Aircell's GoGo Biz, Inmarsat's SwiftBroadband and ViaSat's Yonder Broadband, you can do more on the way, too.
October 1, 2010
Options at the low end of the charter market-single-engine turbine and piston aircraft as well as VLJs (very light jets)-are expanding. That's good news if you've been priced out of larger jets, want to upgrade an automobile or airline trip without busting the bank or are looking to save money on short flights or when traveling without a large group.
August 1, 2010
Embraer entered the light jet market in 2005, promising more for less, and the $8.14 million Phenom 300 delivers. It's fast, has long legs and sports a well-equipped, comfortable cabin with an array of options typically found only in airplanes costing millions more. The Phenom 300 was certified late last year.
August 1, 2010
Applying the language of golf, the Gulfstream IV is a solid par performer. It's a no-drama player that hits straight down the middle, avoids the hazards and posts consistent scores.
August 1, 2010
You've analyzed numerous variables, including where, when and how often you fly. You've determined that a fractional share makes sense for you and figured out which aircraft model best suits your needs. You've even picked a fractional provider. Time to call the company, sign the paperwork and break out the margaritas?
August 1, 2010
Say for a moment that you own an aircraft rather than simply fly on those you charter. Given the direct operating costs and all the other expenses of ownership, how much would you charge a stranger to use your airplane?
August 1, 2010
How would you respond to an in-flight emergency? If your answer involves seeking help from flight attendants, that's not surprising. Passengers typically consider them to be the cabin safety go-to people.
August 1, 2010
Even though I'm a pilot, I still love loading up the car and hitting the highway for a far-off vacation destination. Some of my most relaxing moments have been behind the wheel, with Woody Guthrie's "ribbon of highway" stretched out ahead of the hood ornament.
July 1, 2010
The people who build airplanes believe better times are coming. So do many analysts, who predict that aircraft sales will gain momentum by the middle of next year. When that happens, manufacturers will be ready because they have continued to fund research and development of new airplanes.
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""I've got a list of corporations that have gotten out of their airplanes [because of criticism from politicians]. It is the stupidest thing I've ever seen. When you look at the time and cost savings; it does not make sense not to fly [privately]. You can't let public perception interfere with your business decision to fly. It either is a good business decision or it isn't.""
-business aviation entrepreneur Nick Popovich
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SailNet Community (http://www.sailnet.com/forums/)
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I'm racing!
Today, the fleet captian on Eagle Mountian Lake called and asked me to join their race team. They race every Sunday on a 27 Catalina called "Relentless". There's a picture of the team in action on my blog.
I am SO pumped! Woohooo!
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Sweet Belle! Hey, at some point, tell your skipper about the BFS Global Regatta! Let's see if he can beat the Smacktanic (C27) on a 5 mile speed run.
(Judging by the spin in the picture...I'm screwed.)
I also noticed that these pics my friend sent me are not of "Relentless" but a different boat. I'm just so excited to finally get back on the water. Cmon May 16th!!!
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Great Service! A huge lifesaver when we discovered our hotel restaurant was closed for refurbishment! Already recommended to friends and family. Thank you Garden Grocer!
Have already recommended you on our Disney page.
Excellent, accurate service over two trips with $300+ orders. Extremely responsive customer service. Outstanding reputation from reliable sources (including some guide books and web sites) that is very well deserved. We will continue to use every time we come to the Disney Area. I only wish the service was available back home, too!


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The most populous prison system in the US, facing legal actions and criticism about inmates having to endure oppressive Texas summer heat, is looking to make conditions a bit more bearable at seven locations by installing basic cooling systems.
Texas Department of Criminal Justice officials insist the new devices are not in response to numerous lawsuits alleging that high temperatures inside prison buildings are improperly cruel punishment and have led to inmates' deaths.
A report issued last month by the University of Texas School of Law's Human Rights Clinic found that at least 14 inmates have died from exposure to extreme heat since 2007 in Texas prisons.
Just last week, a federal civil rights lawsuit was filed on behalf of four Texas inmates who contend their health issues are exacerbated by the heat, including an allegation they sleep on concrete floors because their metal bunks are too hot. The suit includes allegations that heat is responsible for 20 prison deaths in Texas since 1998.
Agency spokesman Jason Clark said the medical, psychiatric, education and geriatric areas of prisons are air conditioned, but a cost analysis hasn't been conducted for installing air conditioning in all of Texas' prisons - some of which are more than half a century old.
"But I can tell you it would be extremely expensive to retrofit and air condition," he said
The federal Bureau of Justice Statistics doesn't track heat-related deaths in jails or prisons.
Prison officials won't address the allegations in the lawsuits, saying they don't comment on pending litigation.
Jay Eason, the deputy director of prison and jail operations, said Friday the 28 evaporative coolers are "just something we thought we would try".
The seven units with the cooling systems are part of a 109-unit corrections system that holds about 150,000 inmates.
The actions are no co-incidence, according to Jeff Edwards, a lawyer representing prisoners who find the heat intolerable and families who say their loved ones died behind bars because of high temperatures.
"I'm glad they're taking even a small step," Edwards said. "It's like chiselling granite, that's what happening here. There are eight wrongful death lawsuits pending and a class action lawsuit pending.
"To suggest this is just a co-incidence belies the facts."
Inmates inside a dorm at the Holliday Unit appeared almost oblivious to the sticky heat Friday, laying on bunks in various stages of undress and ignoring a television mounted on a wall above the cooling device. But several said they appreciated the new fan, which blows primarily on prisoners sitting on benches in front of the TV.
"It does its job," said Donald Green, 41, who's serving time for aggravated assault.
Other inmates said prison officers were vigilant about checking on them regularly and ensuring they were hydrated. Some also said they either grew up without air conditioning or were accustomed to the heat because of their work.
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Chalo Raj Bhavan program of Insaaf organization todayHyderabad: National President of Insaaf organization and former CPI MP of Rajya Sabha, Mr. Syed Aziz Pasha will lead the protest rally from Khairtabad Railway Station to Raj Bhavan today to highlight the losses caused to Muslim community due to ... Siasat Daily, 1 week ago
Protest Rally against Modi's Government - HT Syndication, 6 days ago
Atrocities against residents of Ghouse Nagar unfortunate: Aziz Pasha - Siasat Daily, 1 month ago
Rangers allow families to meet detained suspects
KARACHI: Sindh Rangers on Tuesday issued a list of 60 suspects who are under the paramilitary force's preventive detention for 90 days. The Rangers, in a statement on Tuesday, said that the family members of the following 60 suspects can meet ...SAMAA TV, 1 week ago Rangers allow families of 60 suspects to meet them SAMAA TV, 1 week ago
179 x mega cases
Upcoming SlideShare Loading in … 5 1. 179 x Mega Cases 1. On the directions of Honble Supreme Court of Pakistan, a list of 179 cases was submitted before the Court. Later on the same list was uploaded on NAB's website. The original breakup ...SlideShare.net, 1 week ago
Promotion of tax-culture underlined
MAILSI -The Federal Board of Revenue (FBR) is taxpayers-friendly institute and there is no need for the traders to worry. The broadening of tax base and promotion of tax-culture is in the interest of the country and everyone should pay their taxes ...The Nation Pakistan, 2 months ago
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Articles Tagged 'FRA'
Lufthansa adds services from Frankfurt to Alicante and Tirana while Munich gains a new connection to Rzeszow.
A deLUXe FTWA wins this week's trophy
Sending the anna.aero judges a selection of Arch of Triumph images is always going to work out well, as we always choose the best of the bunch for the competition. That's what this week's winner did. Now it can LUXuriate in its glory over the other six competing airports from around the world.
Lufthansa – hats off for Panama City launch
Lufthansa begins five times weekly Jump service to the home of codeshare partner Copa Airlines.
Over 1,200 routes connect Asia to the rest of the world; Mumbai–Dubai is #1; MEB3 hub is also the number one destination from the continent
During the past 12 months, seat capacity between Asia and the rest of the world has grown by 6.2% with Emirates remaining as the largest carrier in the market. With Routes Asia just around the corner, anna.aero thought it would look to see how the world is connecting to the continent, and to highlight some […]
Europe's top 5 airports analysed; Frankfurt, London, Amsterdam, Paris and Istanbul – the FLAPI hubs compared
Europe's five busiest airports handled over 320 million passengers between them last year. We reveal which airlines have been gained (and lost) at these airports and how the number of destinations served compares.
TUIfly consolidates its flying after years of tears; home base Hannover still #1 German airport
Last time we looked at TUIfly was over seven years ago, 18 months after the airline had been created through the merger of Hapag-Lloyd Express and Hapagfly and 30% capacity culls were the order of the day. anna.aero takes a look to see how things have moved on since then.
Istanbul New Airport could help generate over 200 new routes when it opens in 2018; anna.aero reveals over 150 possible new destinations
Last week's ACI Airport Exchange marked the first big public reveal of the details of Istanbul New Airport which is set to open its first phase in 2018. The senior management of both the new airport and Turkish Airlines comprehensively turned out and gave top briefings, while anna.aero unveiled over 200 possible new routes.
Baltimore/Washington boasts with its first Arch of Triumph certificate
Everyone might be busy out Christmas shopping (or doing it all on-line these days), but the world's airports fire crews are still producing FTWAs at a rate that would put Santa's elves to shame. Find out which one of nine global airports has won the penultimate Arch of Triumph title of 2015.
Lufthansa checks-in at Cancún, Malé and Mauritius
Lufthansa's new long-haul off-shoot Jump starts three new leisure services from Frankfurt.
Med-View Airline becomes latest entrant in Nigeria to Europe market; annual growth of 8% includes new Turkish Airlines service to Abuja
Last week the Nigeria to Europe market welcomed a new entrant, as Med-View Airline began a four times weekly service from Lagos to London Gatwick on 20 November. We take a look at the market dynamics over the last 12 months, as well as recent travel habits between Africa and Europe.
Over 2,000 votes cast in W15/16 Cake of the Week competition Part I; Vote for the best Cake of the Week – 13 tasty treats from W15/16 Part II
With over 30% of the votes, Ohio's Akron/Canton Airport saw off the challenge from 18 other global airports, many of which are much bigger than it, to claim the Cake of the Week W15/16 Public Vote Part I. 13 more airports do battle this week to secure the Part II title.
Nearly 1,000 votes cast in W15/16 Fire Truck Water Arch competition Part I; Vote for the best of nine FTWAs in W15/16 launches Part II
With 40% of the votes, Iasi Airport in Romania won the battle against 18 other airports from around the world to claim victory in the Fire Truck Water Arch W15/16 15 Public Vote Part I. Nine more airports take up the challenge this week to secure the Part II title.


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The Bedford Diaries 2006 | TV Show Watchlist
Season 1, Episode 7 Risky Business
First Aired: May 10, 2006
Owen gets jealous when Richard turns to Natalie for comfort after Katrina breaks up with him; Zoe considers losing her virginity to Chris; Lee continues to sink further into gambling; Macklin asks Katrina to go with him to Bermuda; Bonatelle fights to keep the school's clinic open.
Guest Cast
Tom Mardirosian Tom Mardirosian Thaddeus Cole
Aasif Mandvi Kamil Sharif
Dagmara Dominczyk Dagmara Dominczyk Katrina
Cast & Details See all »
- Premiered: March 29, 2006
- Rating: None
- Premise: A New York City college professor presides over a human-behavior and sexuality class in which students videotape their innermost thoughts about their sexual experiences and relationships. (more)
Trending TonightSee all »
The Blacklist9:00 pm | NBCI'll Watch685 Watching
The Big Bang Theory8:00 pm | CBSI'll Watch377 Watching
Bones8:00 pm | FOXI'll Watch317 Watching
Popular Shows
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- 1. Melissa Benoist
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- Cape student sues, accuses school officials of slamming her to ground multiple times (04/28/16)45
- Bob Evans restaurant in Cape Girardeau among chain's 21 closings (04/26/16)9
- Missouri House votes to allow concealed weapons without permits (04/28/16)6
- Two hurt in motorcycle wreck on Interstate 55 (04/25/16)1
- Law firm requests information about Cape's traffic cameras (04/25/16)2
- Local lawmakers split over failed medical marijuana bill; voters may have a say (04/26/16)19
- Police report filed, but no charges in incident at Cape Central (04/29/16)35
- Tanker truck catches fire near Oak Ridge (04/24/16)7
- Local company makes eco-friendly kitty litter that cuts cat-box smell (04/25/16)
- Senator introduces bill for I-57 that would connect Sikeston with Little Rock (04/28/16)4
Southeast Missouri State women's basketball team drops fifth straight OVC game
The Southeast Missouri State women's basketball team appeared poised to take SIU Edwardsville down to the wire and perhaps snap its losing streak.
But a 15-0 run by host SIUE broke a second-half tie and sent the Redhawks to their season-high fifth consecutive defeat, 78-65 Monday night in Edwardsville, Ill.
Southeast fell to 8-13 overall and 2-6 in Ohio Valley Conference play. The Redhawks are 1-10 on the road, including 0-4 in OVC road matchups.
The Redhawks remained fifth in the six-team OVC West Division. They are 10th overall in the 12-team conference halfway through their league schedule. The top eight finishers qualify for the OVC tournament.
SIUE (11-10, 5-4) is tied for third in the West Division.
"I was really proud of the effort we gave tonight. It was outstanding," Southeast coach Ty Margenthaler said after the Redhawks concluded a two-game road trip that began with Saturday's 82-62 loss at Eastern Illinois. "We put ourselves in a position to win, but they go on a 15-0 run and that's the ballgame."
Southeast also hung with OVC power Eastern Illinois before faltering in the second half, which Margenthaler said has been a familiar theme lately.
"Right now we're a 30-minute basketball team. We've got to become a 40-minute basketball team," Margenthaler said.
Monday's game was tight most of the way, with 10 lead changes and 11 ties.
Southeast fell behind 6-0 at the outset but led twice in the first half and entered the intermission down 26-25.
The lead went back and forth for a good part of the second half, the Redhawks going up by three points twice for their biggest advantage of the night.
A basket by Southeast senior guard Bailie Roberts tied the score 53-53 with 9 minutes, 15 seconds remaining, but then the bottom fell out for the Redhawks.
SIUE went ahead 55-53 on two free throws by freshman guard CoCo Moore with 7:54 to play.
Moore's foul shots began the game-deciding 15-0 burst that made it 68-53 with under four minutes left.
The Redhawks missed four shots and committed four turnovers during a five-minute scoreless stretch. Southeast had only 11 turnovers in the game -- well under its average -- but the late miscues were crucial.
"We did a nice job with only 11 turnovers, but we had untimely errors," Margenthaler said. "We had a few silly turnovers. ... We get a little fatigued and that bothers us."
Southeast freshman guard Kara Wright scored a career-high 22 points. That ties the highest-scoring output for any Southeast player this season.
Wright hit 8 of 13 field goals and 5 of 7 free throws. She added five rebounds, two assists and a steal.
Sophomore guard Allyson Bradshaw, a Notre Dame Regional High School graduate, added 17 points for Southeast, which was one off her career high.
Bradshaw tied her career high with 5 3-pointers in 10 attempts. She also had three assists and three steals.
"Kara and Allyson both played really well offensively. They did a really good job," Margenthaler said. "Kara is going to be a special basketball player."
Junior forward Patricia Mack led Southeast with 10 rebounds.
But the Redhawks had no answer for Raven Berry, SIUE's powerful 6-foot-1 senior forward.
Berry poured in a career-high 28 points and grabbed 13 rebounds for her seventh double-double of the season and 31st of her career.
Berry, who entered the night averaging 13.4 points and 9.2 rebounds, became SIUE's all-time rebounding leader Monday. She ranks seventh on the school's career scoring list.
"If not the No. 1 post player in our league, she's definitely in the top two or three," Margenthaler said. "She's a handful. She's strong, she's wide."
It didn't help Southeast that senior forward Courtney Shiffer missed her fifth straight game due to a concussion suffered during practice.
"We're so shallow in our post area and that hurts us," said Margenthaler, who is hopeful that Shiffer will return soon.
It also didn't help the Redhawks that SIUE went 26 of 32 from the free-throw line, while Southeast attempted just seven foul shots, making five. No player other than Wright shot a free throw for the Redhawks.
"It's very interesting, that's all I can say. But I don't think that lost the game for us. We could have done some better things," Margenthaler said.
The Redhawks shot 40.6 percent from the field compared to 43.9 for SIUE. Berry helped SIUE outrebound Southeast 44-29. The Cougars outscored the Redhawks 42-20 in the paint.


text: Wednesday, April 20 Ingrid Fliter joins the San Francisco Symphony, and guest conductor Pablo Heras-Casado to play a Haydn piano concerto in three concerts this week, beginning tonight. The Gilmore Artist Award winning pianist is better known for her Chopin, but brings to her playing a knowledge of the earlier instrument Haydn would have known. There's more information about the concerts, which also include the Beethoven Symphony No. 2, and works by Biber and Rameau at the San Francisco Symphony website. "I love to do this period of music," Fliter says. "I've worked for many years on the fortepiano, and that opened me the doors of a different world… a beautiful rich interesting world to discover... If you don't try those pianos, you don't really know how people played at that time. The way they played, expressively, with their hands, with their body. You have to apply other kind of technique to be able to get from the piano all the voices, all the contrasts, all the colors that at that time they couldn't create with the piano, because it was kind of flat. You cannot use the piano in the way you would use it for Chopin or Rachmaninoff… It's definitely another approach." The challenge is to create the same kind of intimate sound and environment in Davies Symphony Hall, with a modern piano. "I do believe that you can create a very big small world, with intensity, with intention, with ideas, that fly directly to the heart of people. That's what I believe." Tuesday, April 19 The Marin Symphony will present its final Masterworks concerts of this season Sunday afternoon, and the evening of April 26, with a program called Bolero... Music Director Alasdair Neale says the French-themed concert is also 'a tale of two halves,' with a sacred work starting things off before finishing with a couple of orchestral showpieces. There's more information about the concerts at the Marin Symphony website. They'll be joined by soloists, the Marin Symphony Chorus, and San Domenico Singers for the Requiem by Maurice Duruflé, "which is modeled on the Faure requiem, probably the better known of these two pieces," Neale says. "But the Duruflé has an important place in my heart since I first heard it as a student... It's got this feeling of contemplative warmth, and very unique French harmonies. It deserves to be heard more often than it is." For the second half, two French interpretations of the music of Spain. "An entirely different kind of ethos and vibe altogether: excerpts from Carmen, including the Habanera and the Toreador Song, in Bizet's colorful evocation of that whole world… And then at the end, Bolero, and who doesn't love Bolero?" As the work builds over the course of 15 minutes, Neale says his job is to "keep a steady hand on the tiller" as the various wind players are especially featured. "Basically, Ravel takes care of it all. You just do what's on the page, you play the dynamics, and it builds." Monday, April 18 Although it's entirely subjective, and boils down to the choice of the composer, pieces are written in different keys for a reason. Music scholars and composers have weighed in over the centuries about the characteristics of the different keys, and rarely come to a consensus. For F Major, several descriptions include words like 'calm,' 'mild,' and 'contemplative.' There's also a bit of an association with rustic or pastoral scenes, helped along in no small way by Beethoven. Here are the 11 selections used (click and scroll down to make them visible): Beethoven: Symphony No. 6, "Pastoral" Dvorak: String Quartet No. 12, op. 96 "American" Joplin: Solace Mozart: Piano Concerto No. 21, mvt. ii Ravel: String Quartet Vivaldi: 'Autumn' from the Four Seasons, mvt. iii Brahms: Symphony No. 3 Chopin: Ballade No. 2, op 38 J.S. Bach: Brandenburg Concerto No 2, mvt. iii Schumann: Concertpiece for 4 Horns, op. 86 Gershwin: Concerto in F (finale) Friday, April 15 Opera San Jose presents Andre Previn's setting of A Streetcar Named Desire, opening tomorrow night and running through May 1st. Conductor Ming Luke says the Philip Littell libretto was very true to the original text by Tennessee Williams, and Previn used the rhythms of the dialogue in writing the music. There's more information about the production at the Opera San Jose website. The story of Stanley and Stella Kowalski, and what happens when Blanche DuBois joins them in their New Orleans apartment is an iconic part of American popular culture, and much of that has to do with the charged dialogue they exchange. Ming Luke says that's maintained in Previn's opera. " He wants to preserve the cadence of the language as much as possible – and so actually, it's a very difficult job for me, because I have to be following the singers in their natural cadence of speech. Previn was very proud at the premiere when people told him, you know 'I could understand every single word!' He wanted to preserve the directness of the language, and the setting of the language for his audience." As Williams did by using an offstage blues piano, and the dance music (the Varsouviana) that reminds Blanche of a tragedy in her past, Previn accompanies the action with musical ideas that foreshadow and tie together the action. "Previn starts off with the train whistle blaring, and very loud from the full orchestra, and it appears many many times throughout the entire opera as a reminder of Blanche's sordid past. In the very first bars, what you hear directly are the train whistles followed by a clarinet, playing basically a jazz riff. And their alternating between these two major themes happens over and over again. From the very beginning, actually, Blanche's character is waffling between the idealistic past that she tries to maintain, and the reality of her actual very hard life." Thursday, April 14 Two local music series are grateful that pianist Roman Rabinovich was able to come on short notice to substitute for an ailing Nelson Goerner, who was scheduled to play for both the Steinway Society of the Bay Area and Chamber Music San Francisco. The Israeli pianist will bring a program of Haydn, Beethoven, Schumann, and one special work written for him by composer/pianist Michael Brown. There's more information about the performances at the websites of the Steinway Society, and the Chamber Music San Francisco. The Uzbekistan-born Israeli pianist has toured extensively, and takes this kind of substitution in stride: "It happens quite often, you know… people get sick, and their colleagues come and help out. It's quite common, I happened to be free this weekend, and I could do it." He was actually already scheduled to return the following weekend to play with his frequent recital partner, violinist Liza Ferschtman (also through Chamber Music San Francisco) but has to return to New York between the two appearances. His program includes the West Coast premiere of the piece called Surfaces by Michael Brown, which was inspired by another, non-musical passion of Rabinovich: "He wrote a piece for me based on my artwork, loosely based on visual gestures of my paintings. And it was fascinating for me to see the transfiguration of the visual gestures into musical ones... There's a lot of similarity because there's color, there's textures, there's tonalities, both in music and in visual art. But the idea of time is different, because music is… You play a note, and it evaporates. And painting stays. And you can come back to it in a year, and it will be the same. You change, but the painting will stay the same." Wednesday, April 13 The trio called Areon Flutes has been playing together for eleven seasons now, all the while expanding the repertoire for their unconventional grouping of instruments. They've commissioned many new works, and they'll be adding five more to the repertoire this Friday evening when they perform at the Center for New Music through the Guerrilla Composers Guild. There's more information at the websites of Areon Flutes, the Guerrilla Composers Guild, and Center for New Music. The composers who have written works for the performance are Nick Benavides, Patrick Castillo, Eric Choate, Emma Logan, and Ryan Rey. "One of the things we're really excited about with Guerrilla Composers Guild is that they've given us an opportunity and a platform to show more people – not just audience members, but also a group of composers – that this instrumentation is very diverse, and really is legitimate in its own right," Areon's Jill Heinke says. She, with Sasha Launer and Kassey Plaha (who's on maternity leave this season, with Meerenai Shim playing for her) formed the ensemble to build a greater awareness of the possibilites of within the flute family. Audiences sometimes are wary, Heinke says: "When people hear the words 'three flutes' I think that has certain connotations, and people don't want to have their eardrums bleed at the end of the concert. But what we're really capable of is so much more soundscape and beauty with all the different members of the flute family that we utilize in almost every piece... I feel like every composer who was working with us on this project really embraced that and really nailed it, because these are some really gorgeous and exciting pieces." Tuesday, April 12 On an "A-to-Z" edition, a Reflective look at Rachmaninoff's Rhapsody... The not-quite piano concerto that Sergei Rachmaninoff wrote, inspired by the 24th of Niccolo Paganini's Caprices - the theme and set of virtuosic variations originally written for solo violin (allowing the composer to show his prodigious talent). One of the reasons for the continued popularity of Rachmaninoff's Rhapsody on a Theme of Paganini is the beautiful 18th variation, with a melody quite unlike the theme at first glance. It wasn't the first time - nor the last time - the tune would be used by another composer. Liszt adapted the Caprices, and Brahms wrote two books of variations for the piano - just on the 24th alone. It had a lot going for it as a theme, as Paganini demonstrated in his variations, with a strong enough harmony suggested by only the violin, and a form that echoes each four bar phrase, a composer could change a lot, and still remain recognizable, and not make the audience lose its place in the tune. For the 18th variation, Rachmaninoff took the opening theme and inverted it - going down when the theme went up, and vice versa - to discover the memorable lush melody that's so memorable: (The eighteenth variation begins at 14:42 in this performance) Monday, April 11 Oakland Ballet is trying something new - and old - for its next performances. They'll be accompanied only by unaccompanied singers, in a program called A Cappella - Our Bodies Sing. Artistic Director Graham Lustig has choreographed one third of the show, along with Val Caniparoli, the team of Janice Garrett and Charles Moulton, plus three area vocal ensembles. There's more information about the performances, which start in Oakland, and have one show each in San Francisco and Hayward, at the Oakland Ballet website. The three ensembles are Vajra Voices, which specializes in the music of Hildegard of Bingen, and will accompany the Garrett/Moulton dance; the Berkeley Community Chamber Chorus, part of the larger Berkeley Community Chorus and Orchestra, and Nona Brown and the Inspirational Music Collective, an area gospel choir. "It's so wonderfully enriching for our dancers, for our singers, and for our community to be doing something at this scale, at this level," Lustig says. "We actually have 33 singers in this production, 3 musical directors, 4 choreographers, and 12 dancers. We're practically at 50 artists working together. And it's exhilarating. It's just completely overwhelming and beautiful." His own work, called Stone of Hope, is a West Coast premiere, although it includes brand new material for this performance by Nona Brown. The other two works are world premieres. "When we sing, and when we dance, it's very much who we are. It's part of our identity. There's no instrument to be interpreted, you're interpreting yourself. And I think that's the thing that most excited me about the idea of the program." There are performances in Oakland this Thursday through Saturday, and additional performances in San Francisco on the 21st, and Hayward on the 23rd. Friday, April 8 Music that circles and repeats has fascinated composers for hundreds of years... And with repertoire from the middle ages to a world premiere, the San Francisco Girls Chorus joins forces with cellist Joshua Roman for a program called Echoes of the Classics: Canons by Brahms, Franck, and Haydn this Sunday at Herbst Theatre. There's more information about the program at the San Francisco Girls Chorus website. Joshua Roman, who has been friends with SFGC Artistic Director Lisa Bielawa for many years, worked with her and some of the young singers in the episodic opera she's composing for television called Vireo, and they began plans that resulted in this collaboration. He says the repertoire of canons (and near canons) is inspired. "It gives a focus for all of these different pieces throughout the program, and lets the cello become another one of the voices involved. So you get to see all of the different composers, sort of through the lens of this one form, and everyone treats it slightly differently, it's a lot of fun." One of the composers is Roman himself, both in improvisations in some of the works, as well as a new piece called Our Voice, that offers a message of empowerment and possibility for the young singers. "It's kind of about them saying, 'we're in control of who we are, you can't really tell us what to be…' When I first started writing the piece, the idea of a girls chorus, the first thing that comes to mind for me is this angelic sound, these cherubs. And I just wanted to fight that on behalf of them, and help give them a little voice, that they can be that, but they can be a lot of other things as well." Thursday, April 7 Violinist Gil Shaham will be presenting a recital of solo works by J.S. Bach, the Sonatas and Partitas, at Cal Performances on the 14th. The performance will be accompanied by original films by David Michalek. It's repertoire that Shaham shied away from performing live earlier in his career, but he's been playing them over the past dozen years, and recently released them on CD. There's more information about the performance at the Cal Performances website. The solo works for violin are a rite of passage for violin students - like the solo keyboard works, they're challenging, and show what is possible to acheive on the instrument. "This is music that I think violinists like myself, we all know from childhood," Shaham says. "My teacher had it as part of our regular curriculum. All the students played and studied the sonatas and partitas of Bach." But playing them in a lesson and rehearsal setting was a far cry from taking them on stage. "After I finished school, I have to confess, I avoided performing these pieces, and I'm not sure why, looking back. I think I was intimidated. People feel so strongly about this music, and I feel so strongly about this music. I guess I didn't feel confident to present it for an audience. It was 12 years ago when I decided to make a concerted effort (no pun intended) to start playing them in concert. I figured if not now, when, and somehow if I don't start playing them, they're never going to feel more comfortable, they're never going to improve." But as he incorporated them into his concerts, they only grew more important to him: "I discovered what so many other musicians had learned before me. Which is that this is the greatest joy for a musician. There is no greater joy than playing Bach. Nothing is more fulfilling, nothing is more engrossing, nothing is more inspiring, and even today when I go to my practice room, if I'm going to practice some Bach, I'll set aside a maybe half an hour, and then an hour and a half later, I'll be looking at the clock, and where has the time gone? A friend who's a violinist said: 'Whenever I play bach, I feel like I'm a better person that day. I feel like I'm a better violinist that day.' And that's true, that's true, I think Bach's music has this effect on everybody around it – the listeners and the players." Wednesday, April 6 The twelve voices of Stile Antico, the London-based early music ensemble, come to the Bay Area this Sunday afternoon to finish off the San Francisco Early Music Society's 40th anniversary season. They'll sing a program called 'Sacred or Profane,' pairing works for the church that were inspired by secular popular songs or motets. Alto Katie Schofield says this is also an anniversary year for Stile Antico, marking ten years as a professional ensemble. There's more information about the group at the San Francisco Early Music Society's website. The line between the two kinds of music wasn't as clear then as we might think it was, with composers feeling free to borrow and repurpose "earthly" music with more spiritual texts. "That's one prism through which composers of sacred music were able to use secular tunes," Schofield explains. "They were writing for the church, so they were obviously going to set words that had a religious implication, but they wanted to use music that was relevant to people, that people would know. And that was one good way for them to kind of shoehorn popular tunes into their work. People would have known the origin of the music, and... it was done very deliberately." Sometimes it was just a matter of changing a few words. "There are a couple of madrigals, the texts of which have been altered from love poetry that was hugely popular at the time, to kind of the love of Christ for the church, or that kind of religious fervor. It's kind of close to the bone, because it takes all the passion of the madrigals in the context in which they were originally written, and transports that fervor into something which has an overtly religious connotation." Stile Antico presented a 'Tiny Desk Concert' at NPR's Headquarters: Tuesday, April 5 On an "A to Z" edition of State of the Arts, we're stopping at "K" to take a look at the evolution of the Keyboard, from the clavichord to the modern grand piano. As the instruments developed over time, they got bigger, louder, and capable of more nuance. One thing the clavichord is known for is just how quiet it is. It was never meant to be an instrument for performance, beyond a very intimate setting. It was relatively portable, though, and has the distinction of being a keyboard instrument that allows the player to use vibrato - since the "tangent" (the piece of metal attached to the key that makes contact with the string) acts as a finger would on a violin's string, and can be held as the sound fades away, or vibrated. (Although that technique isn't used in this example): The virginal combines the shape of the clavichord with the "plucking" mechanism that's used by a harpsichord. A "plectrum" (usually a bit of a quill feather) and one string per note, gave it a consistent, but still not so loud sound. The harpsichord changed the orientation of the strings - rather than running parallel with the keyboard as on the clavichord and virginal, they go perpendicularly. (Some 'bentside spinets' had strings run at an angle somewhere between) On more elaborate harpsichords, there are multiple strings per key, and sometimes multiple banks of keyboards, which can be mechanically ganged together to create a beefier sound. Bartolomeo Cristofori's invention of the 'Gravicembalo col piano e forte' - which means 'harpsichord with soft and loud' - or piano around 1700 was a breakthrough because it allowed the player to be able to control, note by note while playing, the dynamics of each attack. The mechanism used hammers that would strike the strings and let them ring in a way that previous instruments couldn't. (The music begins :30 into this video): The fortepianos that were fine for Mozart needed to be stronger to withstand the kind of playing and writing that Beethoven demanded, and the science of piano making and the art of music written for the instrument continued pushing eachother on until the the late 19th Century, with the arrival of the modern, metal-framed grand piano we know today. Monday, April 4 Symphony Silicon Valley plays the unforgettable Nino Rota score to The Godfather this weekend, live in performance accompanying the film. It's just the most recent entry in their special films series, which last spring included the sprawling Lord of the Rings saga. Andrew Bales, president and general director of the orchestra says it's a different kind of concert-going experience. There's more information about the performances at the Symphony Silicon Valley website. "What we found from the audience reaction when we did Lord of the Rings is that there is an affinity for movies and the movie culture that is heightened when they hear it with the live orchestra. And that people who really want a special event out of their experience with these films love hearing it with the live orchestra," Bales explains. While this production will be less appropriate for children than some of the other past films they've accompanied (Bugs Bunny and Looney Toons shorts, Fantasia, and earlier this season, Raiders of the Lost Ark) he says as a means of entry into the world of symphonic music, film can't be beat. "There is a willingness to experience the live music with a film that they already have a familiarity to, and having done that, there is this lingering hope that they'll say, 'Hey, that wasn't such a bad thing to do, let's see what else the symphony is doing.' It sort of makes the musicians the stars."


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The explosive dilemma of 'collaboration' with the Nazis in order to save German Jews split the Zionist movement in the 1930s.00:01 01.05.16 | 0 comments
Fifty years ago Jewish students were active in the USA anti-war and civil rights movements. True Judaism has always stood for truth, justice, peace and helping the helpless. These students carryon that tradition. It is Israel that has strayed from Judaism for the sake of nationalism. A piece of land has not sustained Jews through the ages. It is values that have kept us a honored contributor for every host culture we have been fortunate to become immersed.


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I Don't Want to Be Poor Forever
Personal Stories, Advice, and Support 18 People
Financial StabilityI don't want to be rich. Just stable. I'd like to have a small house with a yard large enough for a dog and a garden. I'd like to be able to save some money back for emergencies, and buy the basics that I need, like food, clothing, and other necessities. The rest I would use for...
SpiritOfTheRabbit 31-35, F 3 Responses 1 Oct 4, 2010
Will It Ever Happen?I've seen my parent's house slowly falling down around them over the years as plumbing sprouted multiple leaks, caused water damage in the basement, floors came up, chipped and cut your feet. Mom went on strike and refused to do any more cleaning, leaving enough dirt on the...
warclaw 26-30, F 9 Responses 0 Dec 26, 2010
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But I say have a great journey. You are loved and missed. Be blessed and thank you.
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goodbye to everyone and I wish everyone the best of luck in the future
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