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Palestinian killed as Israel searches for missing West Bank teenagers
June 16, 2014 - 14:21 AMT
PanARMENIAN.Net - Israeli forces searching for three teenagers believed to have been kidnapped swept into a second West Bank city on Monday, June 16 touching off street confrontations in which they killed a Palestinian, witnesses and hospital officials said, according to Reuters.
The bloodshed near the de facto Palestinian capital of Ramallah marked an escalation in a dragnet targeting Hamas, an Islamist group which earlier this month agreed to form a unity government with U.S.-backed Palestinian President Mahmoud Abbas.
Witnesses said Palestinians threw rocks at soldiers conducting house-to-house searches in al-Jalazoun refugee camp, outside Ramallah, before dawn. Army gunfire killed a 20-year-old Palestinian and wounded another, hospital officials said.
The military, which had announced plans to step up its West Bank operations to locate the three Israeli teens who disappeared after leaving a Jewish settlement on Thursday, said it was checking reports on the al-Jalazoun incident.
Israel accuses Hamas militants of abducting the three youths and has rounded up scores of Palestinians in Hebron, a West Bank city where support for the Islamist faction is strong.
The military said on Monday troops had detained 40 Palestinians across the West Bank overnight, "including Hamas leadership and operatives", bringing up to 150 the number of arrests since the search operation began.
Among the detainees were several Palestinian lawmakers from Hamas, including parliament speaker Aziz Dweik, witnesses said.
Israeli Deputy Foreign Minister Tzachi Hanegbi said the search was being conducted in the wider Hebron area and that forces have not yet zeroed in on a particular neighborhood.
"Time is always a negative factor, the more goes by the less positive it is, but our working assumption ... is that the boys are alive and we are exerting every effort to reach them," Hanegbi told Israel Radio.
The crisis is a severe test for Abbas. His security forces have sought to help Israel's search, drawing censure from Hamas.
Israeli Prime Minister Benjamin Netanyahu called off meandering U.S.-sponsored peace talks with Abbas in response to the Palestinian unity deal, which he says emboldened Hamas and its belligerence toward Israel.
"I believe that the dangers of this pact should now be abundantly clear to all. We've seen since the signing of that pact an increase in terrorist activity emanating from the West Bank," Netanyahu said on Sunday, blaming Hamas for abducting the three teenagers and holding Abbas responsible for their return.
Hamas has neither confirmed nor denied Israel's allegation. Some Palestinians close to Abbas accused Netanyahu, who champions Jewish settlement of occupied West Bank land where they seek statehood, of seeking a pretext for further hostility.
On Saturday and Sunday, several rockets were fired into Israel from the Gaza Strip, a Palestinian territory where Hamas holds sway. Israel launched air strikes at training camps used by Hamas and Islamic Jihad, another Palestinian militant group.
There were no serious casualties on either side.
Photo: Menahem Kahana/AFP/Getty Images
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Radiohead teases new music on Twitter, social media Earlier this week saw the band return to the internet to tease fans with new music after erasing their online presence.


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Jerome M. MauroWrong Jerome M. Mauro?
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Music labels file online piracy lawsuits in UK
Record companies in Britain are filing their first ever lawsuits against five people accused of illicitly sharing music online, after settling out of court with dozens of others.
The lawsuits come as the global music industry fights to control online piracy by suing users of illicit file-trading networks, while also promoting legal music services like Apple's iTunes Music Store.
"Music fans are increasingly tuning into legal download sites for the choice, value and convenience they offer," said Peter Jamieson, chairman of the British Phonographic Industry trade group.
"But we cannot let illegal filesharers off the hook. They are undermining the legal services, they are damaging music and they are breaking the law." More than 60 BPI lawsuits have already been settled, with users paying up to 6,500 pounds each in compensation. The BPI first contacted the users in April.
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Octa-core Cortex-A53 hacker SBC sells for $60
FriendlyARM's $60, open spec "NanoPC-T3" SBC runs Android or Linux on an octa-core Cortex-A53 SoC packed with wireless and media interfaces, plus 8GB eMMC. The over-caffeinated board builders at Guangzhou, China-based FriendlyARM have shipped their highest-end hacker board yet. The NanoPC-T3 is almost identical to the NanoPC-T2 board, but swaps out the quad-core, Cortex-A9 Samsung S5P4418 SoC for a layout-compatible S5P6818 with eight Cortex-A53 cores that can be clocked dynamically from 400MHz to 1.4GHz. Last month, FriendlyARM' unveiled an $11, quad-core NanoPi M1 single board computer with similarly open source hardware and Android and Linux software.
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Veggie Bean Burgers
Serve this vegetarian main dish with a side of shredded carrots tossed with a squeeze of lime and a sprinkling of black pepper.
Total Time:
Level: Moderate
Yield: 4 main-dish servings
Serves: 4
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- 2 c. Home-Cooked Beans
- 2 tbsp. light mayonnaise
- ⅓ c. fresh cilantro leaves
- 1 tbsp. plain dried bread crumbs
- 1 tsp. ground cumin
- 1 tsp. cayenne pepper sauce
- salt
- nonstick cooking spray
- 1 tbsp. olive oil
- 4 lettuce leaves
- 1 large tomato
- 4 Hamburger buns
- In large bowl, with potato masher or fork, mash beans with mayonnaise until almost smooth (some lumps of beans should remain). Stir in cilantro leaves, bread crumbs, ground cumin, hot pepper sauce, and 1/4 teaspoon salt until well combined. Divide bean mixture in quarters; with lightly floured hands, shape each into a 3-inch round patty. Lightly spray both sides of each patty with nonstick cooking spray.
- In 12-inch nonstick skillet, heat olive oil on medium 1 minute. Add bean patties, and cook about 10 minutes or until lightly browned on both sides and heated through.
- Arrange lettuce and tomato slices on bottoms of buns; top with patties and bun tops.
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20 year old recently got hooked on adderall. started taking it for all the wrong reasons. the most i've taken within 48 hours is 150mgs. couldnt eat or sleep for almost 4 days. ended up picking at my skin a lot too. and now having severe back pains. what should i do? what could happen if i do that much often?
Is 100mgs of adderall too much at one time?
- Posted:
- 26 Oct 2009 by Anonymous
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- adderall
Answers (1)
30 May 2010
Get some help as soon as possible all that you had said does not sound good at all. When your coming off it you might need some vicodin to control the pain in you back. Basically in your whole entire body it will make you hurt. Please be careful with this drug it is very dangerous.
Further Information
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15 days increased on Zoloft and still having anxiety 50 mg to 100mgs when should I hope to see a change
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Italian Prime Minister Silvio Berlusconi, right, gestures as he gives a speech next to mayoral candidate for Naples Gianni Lettieri, left, during a convention of The People of Freedom Party in Naples on Saturday.May 16, 2011FULL STORY
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Career Opportunities
Currently accepting applications for positions listed below, please click here to submit an application for employment. All applications submitted for positions other than those listed will not be considered.
Current Positions Available:
JOB LOCATION: First State Bank Nebraska - Thompson Creek
- Review residential loan application file, verifies application data is complete and meets secondary market standards, including type and amount of mortgage, borrower assets, liabilities, length of employment and other criteria as required by correspondent investors.
- Transcribe or compose letters, memos and other material related to processing loans. This requires the ability to write exceptionally well, while maintaining the highest standards of professionalism.
- Maintain well-organized, uniform and complete files using checklists and following lending regulations. File all documents in a timely manner. Record collateral (if any).
- Process and verify documents/information received from customers by calling employers, arranging for appraisals, etc.
- Order abstract updates and appraisals.
- Submit mortgage loan application files for underwriting approval.
- Request and gather documentation from customers, businesses and others. Review information and loan documentation prior to submission to underwriting.
- Prepare mortgage loan files for settlement.
- Prepare HMDA data sheets.
- Responsible for MERS Tracking.
- Submit closed loan package to secondary market investors for funding.
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- Adhere to underwriting and quality control requirements in preparing file, maintain investor standards for compliance to policies and guidelines
- Prepare checklist specific to loan program.
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cleveland browns - Page 2
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On Wednesday night the Cleveland Browns traded a bright spot in their roster to the Indianapolis Colts. Does the addition of running back Trent Richardson turn the Colts into a real championship contender?
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Coaching in the NFL is a tough gig. You only have two or three years no matter the team, front office and quarterback to make things happen if you enter a new head post. Who has the toughest jobs this year as rookie NFL head coaches? Here are my Top 5:
NFL Hall of Famer Joe DeLamielleure Talks With The Team
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Posts Tagged 'Wakefield Daily Item'
By MARK SARDELLA WAKEFIELD — The scenario is this: Wakefield Police receive a call reporting a disturbance at Acme Corp., a company of 50 employees located at the end of a cul-de-sac in Wakefield. The company is headquartered in Israel and has been threatened in the past by radical Islamic groups. The threats have come […]
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Red and white blues
It's happening everywhere. The forces of political correctness have been picking off one innocent tradition after another. It hit Wakefield this week. The School Department announced that for this year's High School graduation ceremonies, graduates will wear "gender neutral" gowns instead of the traditional red for boys and white for girls. No, this is not […]
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Debatable questions
The recent candidates debates at WCAT once again proved to be a valuable tool in informing the voters about the candidates and issues in advance of the April 26 Town Election. I was happy once again to have had the privilege of serving on the press panel that posed questions, in two separate debates, to […]
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Tags: Ann McGonigle Santos, Board of Selectmen, Bronwyn Della-Volpe, cable, candidates, Dan Benjamin, David Watts Jr., debate, election, Mark Sardella, Peter May, Phyllis Hull, Politics, Television, Tony Longo, Town Clerk, TV, Wakefield Civic League, Wakefield Daily Item, Wakefield MA, WCAT, William Carroll
by MARK SARDELLA For nearly two hours, Anthony Amore entertained the packed audience at The Savings Bank Theater with tales of art theft and the sometimes colorful but often inept characters that perpetrate such crimes. Amore was the opening speaker in the 2016 Sweetser Lecture Series in Wakefield, Massachusetts. As head of security and chief […]
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Tags: Anthony Amore, Art, art crime, Isabella Stewart Gardner Museum, Mark Sardella, Massachusetts, paintings, Rembrandt, Stealing Rembrandts, Sweetser Lecture Series, The Art of the Con, The Savings Bank Theater, Vermeer, Wakefield Daily Item, Wakefield MA, Worcester Art Museum
Thanks to 'Wakefield Main Streets' program By MARK SARDELLA WAKEFIELD — You've seen the flower barrels currently along Main Street in the downtown filled with colorful plantings from spring through summer. Starting in May, look for some new additions to that downtown beautification effort. The Wakefield Main Streets program will be providing four new self-watering […]
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Tags: Board of Selectmen, downtown beautification, flower barrels, John Ross, Main Street USA, Mark Sardella, Massachusetts, National Trust for Historic Preservation, Paul DiNocco, self-watering planters, Wakefield Daily Item, Wakefield MA, Wakefield Main Streets
Make Main Street one-way
Sometimes the solutions to our problems are so close we overlook them. I am speaking of course of the new "Wakefield Walk" proposal that would make Main Street one-way heading north from the Melrose line to Lowell Street. The northbound lane would remain open to vehicular traffic with no changes. The southbound lane would become […]
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by MARK SARDELLA When it comes to larceny, people seem far more fascinated with art theft and fraud than with other types of robberies and scams. Part of the intrigue likely stems from the myth of the gentleman art thief, according to security expert Anthony Amore, who will kick off the 2016 Sweetser Lecture Series […]
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Tags: Anthony Amore, Art, Art of the Con, art theft, artist, Degas, fraud, Isabella Stewart Gardner Museum, Manet, Mark Sardella, Massachusetts, Rembrandt, Stealing Rembrandts, Sweetser Lecture Series, The Savings Bank Theater, Vermeer, Wakefield Daily Item, Wakefield MA


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Italy's Fincantieri, whose initial public offering started on Monday, will not pay dividends in the medium-term, the shipmaker's Chief Financial Officer Fabrizio Palermo said at the roadshow before the listing.
Fincantieri's Chief Executive Giuseppe Bono explained the company would not pay dividends for the next three years.
The company, which is wholly owned by Italian state lender Cassa Depositi e Prestiti (CDP) through its Fintecna unit, said in a statement on Friday it would offer a stake of up to 38.2 percent stake, mostly made up of new shares, in a price range of 0.78-1.0 euros per share.
CDP's Chairman Franco Bassanini said a further placement of the company could not be ruled out.
(Reporting by Elisa Anzolin, writing by Francesca Landini)
Maritime Today
The Maritime Industry's original and most viewed E-News Service
Louisiana shipbuilder Bollinger Shipyards announced it has secured a contract to build Phase II of the Sentinel Class Fast Response Cutters (FRC) for the United States Coast Guard (USCG).
Another massive reduction in the Korean shipbuilding workforce may come as most shipyards are still struggling with falling orders and mounting losses, reports Yonhap quoting industry sources.
South Korean shipbuilder Daewoo Shipbuilding & Marine Engineering Co. posted a first-quarter loss after incurring more costs to finish some offshore projects.
As the prolonged slump in energy prices continues to drag on a number of oil and gas and maritime players, word has it that Harkand Group has succumbed, according to staff reports and a report on www.
Agricultural commodity traders Louis Dreyfus Co B.V. and Amaggi Group have hired HSBC Holdings Plc to sell part or the entire 25 percent stake they hold in a terminal at the Brazilian port of Itaqui,
International Transport Intermediaries Club (ITIC) says it continues to deal on a regular basis with claims resulting from errors by agents involving transhipment cargoes.
The U.S. Coast Guard announced last week that state-calibrated scales already in use at the Port of Savannah meet a new requirement of the international Safety of Life at Sea (SOLAS) Convention.


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Real news. Real funny.
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text:
Lake Chelan School District is seeking
applicants for the
following positions:
2016-2017 school year
• Middle School/
High School Counselor
• CTE Woodshop Teacher
• ELL Intervention
• Holden Village
• AFTERS leaders
• High School Girls
Basketball Assistant Coach
• High School Volleyball Assist Coach
• 8th Grade Football Coaches
Year-round positions
• Substitute Teachers
& Paras
• Substitute Custodians
• Substitute Food
• Substitute Bus Drivers
Detailed job postings and online application process are available at:
For assistance, call 509-682-3515
Heidleburger Drive-In now hiring full-time cook/ fry cook. Need to have experience. Ñeed to be available on weekends and nights. Fast paced work environment, excellent pay plus tips. Come in and ask for application. 12708 Hwy 2, Leavenworth.
Heidleburger Drive-in now hiring for part-time/ full-time counter person for summer. Needs to be available on weekends. Come in and talk to Niki. 12708 Highway 2, Leavenworth.
Cascade School District is seeking qualified applicants for the following positions:
• Kindergarten Teacher
• Elementary Bilingual
Translator/ Assistant
Fast Track application process and additional information can be found on our website at:
Wapato Point is recruiting for the following
Maintenance Techs:
1 Full-time & 2 Seasonal
Maintenance Pool Techs:
2 Seasonal
Recreation Associates:
1 Full-time & 3 Seasonal
Front Desk Associates:
1 Part-time/ Year-round
& 2 Seasonal
Grounds/ Driftwood:
2 Seasonal
Position descriptions and application packets for all positions are located on our website at
http://www.wapatopoint.com .
For questions, please call
687-9511, x307
Manson School District is seeking applicants for the following positions for the 2016-2017 school year positions:
• 1 year leave replacement Certificated Elementary Teacher
Detailed job posting and online application process are available at: http://www.manson.org EOE
The City of Brewster has an opening for a full time, year round water/ utility worker. As this is a union position, wages and benefits are dictated by union contract. Please see the citys website for a full job description.
Interested individuals can pick up application packets at City Hall, 105 S. 3rd St. or visit the Citys website: cityofbrewsterwashington.org A cover letter and resume will need to be provided along with the completed application packet. Applications are due by Friday May 13th at 4:00 p.m.
Sunset Bar in Manson is looking for immediate hires of cook, dishwasher, bartender and server positions, part-time and full-time. Weekly pay and 401K offered. Must be 18 for dishwasher and 21 for other positions. Deliver or email resume to firstname.lastname@example.com
Staff for new wine tasting room in Manson. Open 12-5 Friday- Sunday. Staff needed for retail hours, plus set up and clean up time. Must be 21 or older. Must obtain or hold a current alcohol servers permit. Background checks performed for this position.
For application, visit
Cascade School District is seeking qualified applicants for the following position:
• Payroll Specialist
Fast Track application process and additional information can be found on our website at:


text:
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Route Sales Support (CDL-B) - Full Time - Peoria, IL - 52 hours weekly - $16.49 hourly
Peoria, IL
Route Driver
Airgas - Driver Careers
Bloomington, IL
Logistics Manager- Bulk Midwest Region
Morton Salt
Chicago, IL
Internal Medicine: General - Physician - Physicians Only Apply - Perm
The Delta Companies
Olney, IL
12T Technical Engineer
National Guard
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Technical Engineer
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PHOENIX — The Phoenix Citizens Transit Commission unanimously approved a proposal for the Police Department to switch to a private security company to monitor the passengers for the Phoenix stretch of the 19-mile light rail system, according to The Arizona Republic. Staffing constraints due to budget issues have made it challenging for police to attain passenger inspection goals set by Metro, according to police officials.
The other two cities the system runs through — Mesa and Tempe — already use private security companies. The measure will go to the Transportation, Infrastructure and Sustainability Subcommittee and the City Council, which are expected to approve it later this month. For the full story, click here.
Applicants can request funds for safety improvements to railroad infrastructure, including railroad crossings, track, tunnels, bridges, yards and other areas.
Service has been hampered since overhead catenary wires were yanked down when a dump truck lowered its bed two days ago. There is no timetable for the repair of the wires.
Passengers aboard the train described a tense atmosphere, with smoke in some of the railcars, flames visible outside the train and the odor of electrical smoke evoking memories of the Jan. 12, 2015, L'Enfant Plaza Metro station incidnet that left one rider dead and scores sickened
Collaborated with Network Rail to develop an interlocking solution based on Alstom's Smartlock range that will be ready for ETCS installation allowing trains with ETCS capability to operate on that section of the line.
The contract outlines a $10 million budget to construct the streetcar line.The city wants the money to come from property owners near the streetcar line, but they rejected it in a vote last year.
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Memory Bank Computers(MBC) in Trinidad and Tobago was established over 23 years ago. We are in the business of Information Systems Technology (IST) where our portfolio covers Service Support, Sales and supplies. Our range of products in the I.T. field includes the following;
LAN Workstations and Personal Computers (PCs)
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Laptops / Mobiles.
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...other peripheral hardware (e.g. Digital Cameras, Projectors, etc.)
In the Technical services arena, we provide the following;
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text:
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A growing number of colleges are cutting tuition or speeding up the rate at which students can attain a degree in order to boost enrollment -- and their bottom line.
|Runway Injustice: How the modeling industry exploits young workers
|Chris Matthews' Melania Trump remarks caught on hot mic
|Apple has killed one of Steve Jobs' favorite projects from 1996
|Donald Trump: 'I'm the king of debt'
|Famed investor sounds the crisis alarm on U.S., China


text:
From parliament to poster: BSP hoarding shows Mayawati as Kali...BJP state spokesman Vijay Bahadur Pathak said his party had taken offence with the BSP ridiculing Hindu gods DNA, 6 days ago
BJP criticises Mayawati over BSP's poster depicting her as 'Goddess Kali' - Equilibrio Informativo, 4 days ago
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Akhilesh only talking, not acting ..
Attacking Akhilesh Yadav, Bharatiya Janata Party's state spokesman Vijay Bahadur Pathak said if th e chief minister felt so strongly about the graft cases during the BSP regime between 2007-2012, why has there been no action against the tainted ...Samaylive, 1 week ago UP graft cases: BJP slams Akhilesh for all talk and no action Firstpost.com, 1 week ago Akhilesh only talking, not acting against graft: BJP Prokerala, 1 week ago Akhilesh Yadav only talking, not acting against graft cases during BSP regime: BJP Economic Times, 1 week ago
More from: IANS Live, IANS Live...and 6 other sources
BJP accuses Akhilesh of taking cre..
State spokesman Vijay Bahadur Pathak said the drought relief material which the state government was distributing in Bundelkhand was of the National Disaster Relief Fund (NDRF). Around 75 percent share of the relief fund was of the union ...Samaylive, 3 weeks ago BJP attacks Akhilesh on CAG report.. Samaylive, 1 month ago BJP attacks Akhilesh on CAG report on unspent budget money Prokerala, 1 month ago
Shame for Swachh Bharat: BJP spokesperson caught urinating in Ganga!
Allahabad, Feb 23: In a major embarrassment to the BJP, a top bureaucrat Vijay Bahadur Pathak was caught peeing in the holy river Ganga, shortly after addressing an event over need of toilets in Uttar Pradesh. His video of urinating in public went viral on ...One India, 2 months ago
KC new NBA president
Kathmandu, April 8 Advocate Sher Bahadur KC of democratic panel became new president of the Nepal Bar Association, as he polled 3,798 votes, defeating his nearest rival representing the progressive panel Bijay Kanta Mainali, who got 3,615 votes. ...Himalayan Times, 3 weeks ago
BJP targets govt over Deoria jail violence
The article below represents a preview only and is not meant for reuse or republishing. Lucknow, April 27 -- The BJP has claimed that the Deoria jail clashes were a result of corruption as the police and jail officials were trying to fleece the ...HT Syndication, 4 days ago
PM to launch Pradhan Mantri Ujjwala Yojna on may 1
e on the Dalit vote bank, Prime Minister Narendra Modi will launch the Pradhan Mantri Ujjwala Yojna (PMUY) from politically-sensitive Ballia onMay 1. There he is expected to announce giving 5 crore free LPG connections to the Below Poverty Line ...New Delhi Pioneer, 5 days ago Mayawati attacks PM Modi's 'Stand Up India',says BJP wooing Dalit vote bank Samaylive, 3 weeks ago Stand Up India scheme an eyewash, PM Narendra Modi just wants Dalit votes, says Mayawati Financial Express, 3 weeks ago Mayawati Calls PM Modi's 'Stand Up India' an Eyewash New Indian Express, 3 weeks ago
UP polls: Team Keshav likely to take shape by May 10
LUCKNOW: Team Keshav to take UP BJP into Vidhan Sabha election is expected to be announced in three weeks of time from now. Home work is complete, said BJP UP in charge Om Mathur. However, when asked about the date, he said 'sooner than expected'. ...Times of India, 5 days ago
UP BJP presiden to hold first meeting with old office bearers tomorrow
Lucknow, Apr 26 (UNI) The first meeting of the state office bearers of Uttar Pradesh BJP after the appointment of new president Keshav Prasad Maurya would be held here at the state party headquarters tomorrow. Party spokesperson Vijay Bahadur ...United News of India, 5 days ago
After BJP Leader As Krishna Now Posters Showing Mayawati As Godess Kali Surface In UP
An FIR has been registered by Uttar Pradesh Police after a poster, depicting BSP supremo Mayawati as Goddess Kali surfaced at a rally in Hathras district on Sunday. Hindustan Times The poster showed the BSP chief holding the severed ...Indiatimes, 5 days ago After BJP Leader As Krishna, Now Posters Showing Mayawati As Godess Kali Surface In UP Indiatimes, 5 days ago
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text:
|Publication number
|Publication type
|Application number
|Publication date
|Aug 30, 2005
|Filing date
|Sep 23, 2002
|Priority date
|Oct 18, 2001
|Fee status
|Also published as
|Publication number
|Daniel W. Viitala
|Original Assignee
|Terumo Cardiovascular Systems Corp.
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (6), Referenced by (7), Classifications (11), Legal Events (3)
|External Links: USPTO, USPTO Assignment, Espacenet
This is a Continuation-In-Part of U.S. Ser. No. 09/978,699, filed Oct. 18, 2001, now abandoned.
This invention relates to venous drainage catheters, and especially to multi stage venous catheters.
A venous drainage catheter is used during cardiac surgery to remove blood from or near the patient's venous system. The removed blood is conducted to heart lung equipment which treats the blood, e.g., by removing carbon dioxide, infusing oxygen, heating, cooling, etc. before returning the treated blood to the patient.
The catheter includes drainage openings for conducting blood from the right atrium and/or vena cava.
During introduction of the catheter into the patient's body, or during subsequent adjustment of the catheter, the catheter may become bent, which tends to produce kinking that will undesirably reduce blood flow. Consequently, it is conventional to reinforce the catheter to prevent such bending.
For example, U.S. Pat. No. 4,639,252 discloses a catheter reinforcement in the form of a cylindrical plastic sleeve embedded in the plastic body of the catheter, with drainage openings punched through the body and sleeve.
In U.S. Pat. No. 5,769,828 a catheter reinforcement is disclosed which is comprised of axially extending beams spaced circumferentially apart. Alternating pairs of adjacent beams are interconnected at their forward or rearward ends by a circumferentially extending connecting piece. There is thus provided a reinforcement which is capable of being expanded over a larger diameter. Drainage holes are punched through the body of the catheter in spaces formed between adjacent beams.
Reinforcement for a catheter disclosed in U.S. Pat. No. 6,152,911 comprises a coil spring defining spaces between successive turns of the coil. Drainage openings are formed in those spaces.
Common to each of the above-described reinforced catheters is the creation of a uniform reinforcement along a section of the catheter. Although such uniform reinforcement resists the tendency for kinking to occur in that section, it also resists the bending of the catheter thereby considerably limiting the flexibility of the section.
It would be desirable to provide a venous drainage catheter with reinforcement which produces minimal resistance to bending thereof while effectively resisting kinking.
The present invention relates to a venous drainage catheter which comprises a flexible elongated tubular plastic body having distal and proximal ends and an interior lumen extending from the distal end to the proximal end along a longitudinal access of the body. The interior lumen has a plurality of longitudinally spaced drainage openings formed in a reinforced opening-containing section of the body. Each opening extends from the outside of the body to the interior lumen for providing fluid communication between the interior lumen and the exterior of the catheter. Reinforcement is embedded in the plastic body within the reinforced opening-containing section. The reinforcement comprises a plurality of annular elements oriented substantially perpendicularly to the longitudinal access of the body, wherein at least one of the drainage openings is disposed between and spaced from an adjacent pair of the annular elements. No portion of the reinforcement interconnects the annular elements.
Alternatively, the annular elements could be formed by a continuous wire which is wound a few turns to form each annular element and includes a connecting section extending helically from one annular element to the next.
The reinforced opening-containing section of the body could extend rearwardly from the distal end of the body, or be disposed only in an atrial basket region which is spaced rearwardly from the distal end.
The objects and advantages of the invention will become apparent from the following detailed description of a preferred embodiment thereof in connection with the accompanying drawings in which like numerals designate like elements and in which:
The present invention is applicable to flexible venous drainage catheters having drainage openings formed therein which communicate with a central lumen for draining blood from a patient.
For example, depicted in
Front and rear elongated main helical reinforcing coils 23, 25 are embedded in the body 12 on opposite sides of an atrial basket region 24 of the body, in a conventional way. The atrial basket region 24 constitutes a reinforced opening-containing section of the catheter body. Formed in the atrial basket region 24 is a series of drainage openings which extend radially into communication with the lumen 20. The size, number, shape, and relative location of those openings can vary. Depicted are front elongated drainage openings 26 f, rear elongated drainage openings 26 r, and circular intermediate drainage openings 26 m.
During use of the catheter, the distal end section is positioned in the inferior vena cava of the heart, and the atrial basket region 24 is positioned in the right atrium of the heart. Thus, blood is drained from the inferior vena cava through the distal openings 18 and the lumen 20, and blood from the right atrium is drained through the openings 26 f, 26 m, 26 r and the lumen 20.
In order to resist kinking as the catheter is being bent while maneuvered into position, the catheter is provided with flexible reinforcement. That reinforcement includes: the front main coil 23 positioned in front of the atrial basket region 24 in a transition region 27 of the catheter, the rear main metal coil 25 situated behind the atrial basket 24, and an atrial basket reinforcement to be discussed. The front main coil 23 gradually increases in diameter toward the atrial basket region 24, whereas the rear main coil 25 is of uniform diameter. As can be seen in
The atrial basket reinforcement comprises a pair of separate annular elements, or ringlets, 42, 44 each of which has an outer diameter D and a very short length dimension L in the axial direction of the catheter. The diameter D is substantially longer than the length as can be seen in FIG. 3. Also, an axial spacing S between adjacent annular elements is greater than the length L as can be viewed in FIG. 2. The ringlets 42, 44 are spaced axially apart from one another along the axis 14 and are spaced axially from each of the front and rear main reinforcing coils 23, 25 (see FIG. 3). Each of the annular elements 42, 44 is preferably in the form a helical metal coil which comprises at least one helical turn, but no more than a few closely wound helical turns, e.g. fewer than five turns, preferably about two and one-half turns. No portion of the ringlets 42, 44 extends parallel to the center longitudinal axis of the catheter, as is evident from FIG. 3.
The atrial basket region 24 is thus subdivided in the axial direction into no fewer than three axially spaced sections, i.e. a front section 50 a, an intermediate section 50 b, and a rear section 50 c (see FIG. 2). An annular row of openings is formed in each of those sections 50 a-c. That is, a row of the circumferentially spaced openings 26 f is formed through the body in the front section 50 a, each of which openings 26 f being elongated in the axial direction of the body. A row of the circumferentially spaced openings 26 m is formed through the body in the intermediate section 50 b. A row of the circumferentially spaced openings 26 r is formed through the body in the rear section 50 c, the openings 26 r being elongated in the axial direction of the body. The opening 26 f, 26 m, 26 r can be of any size and shape (e.g., circular, oval, triangular, etc.) and in any combination of sizes and shapes.
It will be appreciated that the spacing of the ringlets 42, 44 from one another in the axial direction of the body means that the sections 50 a, 50 b, 50 c will be non-reinforced and thus capable of freely bending according to the flexibility of the body itself (see FIG. 5). Thus, the atrial basket is provided with minimal reinforcement, i.e. reinforcement occurs only at axially spaced points. The rest of the atrial basket is non-reinforced and capable of free, uninhibited bending. There is thus no continuous resistance to bending along the entire atrial basket as occurs in the above-described U.S. Pat. Nos. 4,639,252; 5,769,828; and 6,152,911, which resistance limits the maximum bending angle. The catheter 10 functions to drain blood from the inferior vena cava and the superior vena cava of a patient's heart, as described earlier, except that the catheter is able to bend, without kinking, in the atrial basket 24, to a greater extent than the above-described patents.
The ringlets 42, 44 are embedded in the plastic material of the body 12 (e.g., plastisol, or polyvinylchloride, etc.). The manner of embedding the ringlets 42, 44 can be the same as that used to embed the reinforcement in the three above-mentioned patents, the disclosures of which are incorporated by reference herein. That is, a mandrel-and-drip process can be used wherein a mandrel is first dipped in liquified plastic material. Then, the main coils 23, 25 and the ringlets 42, 44 are disposed around the plastic, whereafter the mandrel is re-dipped to embed the coils in the body 12.
The ringlets 42, 44 need not comprise helical coils. Rather, they could comprise other types of annular members, such as rigid circular rings, although coils are preferred.
In accordance with the invention, the problem involving the atrial basket being inadequately bendable is avoided, while ensuring that the atrial basket cannot bend to such an extent that kinking occurs.
Depicted in
Depicted in
The distal section 60 is shown as being of forwardly tapering shape, wherein the ringlets 42 are of progressively diminishing diameter in the forward direction. However, instead of being tapered, the distal section could be of constant diameter, i.e., cylindrical as shown in another embodiment of a catheter 80 depicted in FIG. 8. In the catheter 80, the distal section 82 in which the drainage openings are formed is of somewhat shorter length than that of
In the reinforcement formed by the ringlets 42 of the above-described catheters 10, 60, 80, the ringlets 42 are not interconnected by any portion of the reinforcement. However, in a somewhat modified catheter 90, depicted concept, shown in
Common to each of the catheters 10, 60, 80 and 90 disclosed herein is a reinforced drainage section having reinforcement in the form of a plurality of annular reinforcing elements 42 or 42 a each arranged perpendicularly to a longitudinal center axis of the catheter, and no portion of the reinforcement extending parallel to the longitudinal axis A.
Although the present invention has been described in connection with a preferred embodiment thereof, it will be appreciated by those skilled in the art that additions, deletions, modifications, and substitutions not specifically described may be made without departing from the spirit and scope of the invention is defined in the appended claims.
|Cited Patent
|Filing date
|Publication date
|Apr 5, 1985
|Jan 27, 1987
|Research Medical, Inc.
|Venous return catheter
|Jun 13, 1996
|Jun 23, 1998
|Medtronic, Inc.
|Two-stage venous cannula with expandable reinforcing member
|Jun 2, 1995
|Sep 15, 1998
|Kenda; Rajko
|An implantable catheter having intermediate length section of greater flexibility than remaining lengths
|Aug 27, 1998
|Nov 28, 2000
|Chase Medical, Inc.
|Venous return catheter having multiple helical support members
|Jan 19, 1999
|Jul 29, 1999
|Heartport, Inc.
|Cannula and method of manufacture and use
|Nov 7, 2000
|May 17, 2001
|Edwards Lifesciences Corporation
|Venous return cannula with enhanced drainage
|Citing Patent
|Filing date
|Publication date
|Apr 24, 2008
|Nov 19, 2013
|Terumo Cardiovascular Systems Corp.
|Even-flow multi-stage cannula
|Jun 25, 2010
|May 27, 2014
|Coloplast A/S
|Urinary catheter
|Feb 22, 2005
|Aug 24, 2006
|Schneiter James A
|High flow diffusion catheter
|Mar 13, 2007
|Sep 20, 2007
|Goldenberg Alec S
|Aspiration needles
|Apr 24, 2008
|Oct 29, 2009
|Terumo Cardiovascular Systems Corporation
|Even-Flow Multi-Stage Cannula
|May 21, 2009
|Apr 22, 2010
|Td.Jam Medical Technologies , Llc
|Devices for Superficial Femoral Artery Intervention
|Jun 25, 2010
|May 31, 2012
|Coloplast A/S
|Urinary Catheter
|U.S. Classification
|604/525, 604/508
|International Classification
|Cooperative Classification
|European Classification
|Nov 22, 2002
Owner name: TERUMO CARDIOVASCULAR SYSTEMS CORPORATION, MICHIGA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:VIITALA, DANIEL W.;REEL/FRAME:013522/0069
Effective date: 20021119
|Dec 29, 2008
|Fee payment
Year of fee payment: 4
|Jan 25, 2013
|Fee payment
Year of fee payment: 8


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Anyone else's LOs not interested in toys? My DS watches me play a bit but won't reach for them, even when just out of his reach. If I put a block or link in his hand he may pass it between hands but drops it quickly. Sometimes I have difficulty getting him to grasp the toy even! :(
Toy time = bore time
Posted 02/01/2013
Moo 05.08.12 (oYo)
Moo 05.08.12 (oYo)
Bug 04.14.14 (oYo)
Bean EDC 08.07.16
Comments (2)
Posted 02/02/2013
My lo was like that for a bit. Then I would put lots of different kinds of toys (blocks, links, stuffed animals, noise makers, balls, cars, etc) around lo. See which kinds of toys interest him. I would also leave books scattered around too. My living room usually looks like the toy chest threw up. I would lay with lo and read books or play with a toy next to lo. Sometimes lo watched me. Other times she would be listening to me read or playing/reaching for toys. You are doing the right thing by offering him the toys. Keep doing it. Teach him to play. Soon he will be playing on his own.
Posted 02/02/2013
My guy was like this for awhile. He just considered his hand and feet to be way more fun than toys. He also had a phase where he preferred fabrics and blankety things. His toy interest seems to be picking up though...
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Mobile ESPN, a national mobile phone service designed for sports fans, now offers a variety of new features for subscribers to follow the 2006 Major League Baseball season. Subscribers have one-touch access to personalized text and video coverage of their favorite teams and players, as well as complete mobile access to their ESPN.com fantasy baseball teams.
Mobile ESPN wireless network voice and data services are provided on the Nationwide Sprint PCS Network. High-speed data services are available in the Sprint wireless high-speed data (EVDO) coverage areas. Where available, "EVDO" provides broadband-like download speeds, enabling extremely fast access to Mobile ESPN's sports content, Internet searching and certain downloads.
Rate plans start at $34.99 a month, and include voice minutes and all ESPN sports content, text messages and wireless Internet access. Handset prices start at $99.
Mobile ESPN is available through Best Buy stores nationwide at www.mobileespn.com.
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Life as Art: 'Mapplethorpe: Look at the Pictures' Follows the Photographer's Gaze
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This Profile Piece Just Might Inspire You to Leave Your Desk Job


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Well met at Audiko, where you may download killer ringtones for your smart phone. Today we have a ringtone of "The Big Blue Overture" by Eric Serra as well as 272 other ringtones by Eric Serra. "The Big Blue Overture" is one of the best tracks from the "Le Grand Bleu" album that was issued by Eric Serra at their recording studio together with other 29 tracks. You can listen to all 4 Eric Serra – "The Big Blue Overture" ringtone variations available here and download it for free to your PC. You can also get other 6 albums produced by Eric Serra for all time. "The Big Blue Overture" is referred to Soundtrack, and we have a huge amount of Soundtrack tracks absolutely for free. And finally, we have collected lyrics for this track and you can view it here as well. So feel free to browse, listen, download ringtones at Audiko.net. Make your phone sound cool!
Eric Serra The Big Blue Overture Ringtone
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Physiological Adaptations for Breeding in Birds is the most current and comprehensive account of research on avian reproduction. It develops two unique themes: the consideration of female avian reproductive physiology and ecology, and an emphasis on individual variation in life-history traits. Tony Williams investigates the physiological, metabolic, energetic, and hormonal mechanisms that underpin individual variation in the key female-specific reproductive traits and the trade-offs between these traits that determine variation in fitness. The core of the book deals with the avian reproductive cycle, from seasonal gonadal development, through egg laying and incubation, to chick rearing. Reproduction is considered in the context of the annual cycle and through an individual's entire life history. The book focuses on timing of breeding, clutch size, egg size and egg quality, and parental care. It also provides a primer on female reproductive physiology and considers trade-offs and carryover effects between reproduction and other life-history stages. In each chapter, Williams describes individual variation in the trait of interest and the evolutionary context for trait variation. He argues that there is only a rudimentary, and in some cases nonexistent, understanding of the physiological mechanisms that underpin individual variation in the major reproductive life-history traits, and that research efforts should refocus on these key unresolved problems by incorporating detailed physiological studies into existing long-term population studies, generating a new synthesis of physiology, ecology, and evolutionary biology.
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Additional Info
|University Press Group Ltd
|Publication date
|3 Aug 2012
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SDPD sgt.'s racism case to go forward
Judge rejects city attorney's bid to keep evidence from public
Dorian Hargrove 3:30 p.m., April 29
I took this photo a couple of weeks ago while walking on the Oceanside Pier.
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Posted January 26, 2014
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The media is often criticized for showing violent and disturbing imagery. Movies, TV, video games, tabletop RPGs, comic books, and various other things have all gone through periods where they're blamed for exposing children to dark and unsettling things. But as these fine art examples prove, violent and disturbing imagery is nothing new.
(Obviously, this article contains some disturbing content.)
1. Peter Paul Rubens - Massacre of the... READ ON
With record-breaking temperatures sprouting up everywhere this summer, there's no better time to cool off with a nice refreshing milkshake. Of course, while some people are content with strawberry, chocolate or vanilla, others want more variety. Here are some of the weirdest milkshake flavors you're likely to ever come across.
1. Foie... READ ON
Eugenol, the active ingredient in clove oil, is the culprit. Clove oil has been used to numb toothache pain since Medieval times. The ancient Chinese also routinely chewed cloves to freshen their breath before talking to the emperor.Cloves are the unopened, dried buds of the myrtle tree. The bud oil is the premium product and is used as a food seasoning and in perfumes. The leaf oil is not usually used in its crude form, but is further processed to isolate the eugenol. Eugenol is still used as a... READ ON
"I Don't Like Mondays"
Written by Bob Geldof (1979)
Originally sung by The Boomtown Rats
The Music
It may be the catchiest murder ballad of all time. Laced with baroque piano flourishes and a call-and-response style chorus, the song is an earworm that makes you feel a little guilty for singing along. After all, you are echoing the words of a convicted killer. "I Don't Like Mondays" was born in January 1979, when Bob Geldof, lead singer of Irish pop band... READ ON
Good luck solving today's mentalfloss.com Brain Game Monday Math Square challenge:
Place the digits 1 through 9 in the white blanks so that the mathematical equations work both across and down. Each digit 1 through 9 should appear only once in the main grid (the red square).
Here is the SOLUTION.
NOTE: These puzzles rarely (but occasionally) have alternate solutions that fit the rules. If you find one of these, first make sure that you've followed the instructions to the letter, then pat... READ ON
Back to School Boot Camp. Pay attention: do not eat paste, and do not take your pants off.
Fight Songs: Eleven Great Musician-Politician Campaign Feuds. Before selecting your campaign music, better check out the politics of the musicians.
Finally, an honest trailer for The Hunger Games. I learned more about the story from this than I ever did from my kids.
Tips for backing up your Gmail, Facebook, and Twitter accounts, and why that's something people should do.
A couple of three-week-old... READ ON
This week, Nintendo released "New" Super Mario Bros. 2. But "Old" Super Mario Bros. 2 isn't what you think it is. Here's the odd story of how Nintendo crammed Mario into places he was never meant to be.
Super Mario Bros. 1... READ ON
An interesting article as the NFL season starts to rev up about why it's getting harder and harder to watch and support football. As a die-hard Falcons fan, it's a difficult question to wrestle with. Though overall I think its dominance in our culture is underestimated in this article.
Cool stuff here -- "The Guardian Eyewitness app for iPad has seen nearly a million downloads since its launch in April 2010. As the app relaunches, we list the top 10 most popular and most shared images from the past... READ ON
"How does light look in slow motion?" asks Ramesh Raskar in this brief TED Talk, demonstrating his "femto-photography," a slow motion technique that achieves one trillion frames per second. He proceeds to show us: the camera captures so many frames that you can SEE LIGHT TRAVELING THROUGH WATER. You can see light moving across the surface of a tomato. It's frickin' insane.
Oh, by the way, this technology can also see around corners. It's not perfect but, you guys, it took me like a whole... READ ON
In 1865, six-year-old Teddy Roosevelt watched Abraham Lincoln's funeral procession in NYC.


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The Castro theater is the oldest theater in California, the seats are cramped, the sound is marginal and the screen is smaller than modern ones - yet the experience of seeing ANY film at the Castro beats any other movie-going experience available! Get that popcorn with REAL...more butter and enjoy the experience of a movie at the Castro! I simply cannot describe how extraordinary this theater is!view less
Downtown Amc Movie Theaters
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1. AMC Metreon 16
135 4th St Ste 3000San Francisco, CA 94103
From Business: Screen Count: 16
2. AMC Van Ness 14
1000 Van Ness AveSan Francisco, CA 94109
From Business: Screen Count: 14
3. AMC Van Ness 14
Great theater! Great parking - convenient, but a tad expensive. Also, the gym I used to belong to, I believe, is at the same building. I say used…
4. AMC Theatres - CLOSED
1881 Post StSan Francisco, CA 94115
5. AMC Emeryville 16
Theater #9 @ 8:00PM is very dirty inside.
6. Amc Bay Street
5614 Shellmound StEmeryville, CA 94608
7. AMC Bay Street 16
This movie theater is not bad. The seats are comfortable and the floors seemed clean. I hate sitting in a theater with sticky floors. The prices are…
8. AMC Theaters
45200 Industrial DrFremont, CA 94538
9. Amc Kabuki Cinemas
1881 Post StSan Francisco, CA 94115
10. AMC NewPark 12
400 Newpark MallNewark, CA 94560
From Business: Screen Count: 12
11. AMC Theatres - CLOSED
983 Grant StBenicia, CA 94510
12. California Film Institute
What a class-act this place is! I'm so glad that San Rafael pieced this place back together to offer such a unique movie-going experience!!
13. Delancey Street Foundation
600 The EmbarcaderoSan Francisco, CA 94107
14. Wharfmasters Inn
785 Port RdPoint Arena, CA 95468
From Business: Perched on a cliff over looking a secluded cove sits the historic Wharf Master's Inn hotel. Stunning ocean views and luxurious accommodations await all who venture …
15. Sonoma International Film Festival
103 E Napa StSonoma, CA 95476
16. MetreonMenu
This is one of the main places I come to see movies in San Francisco. They always have a wide selection of movies and times, so it's great for a spo…
17. Marina Theatre
good place. good seating. great concessions great food good people. great movie selection. nice neighborhood theatre. always enjoy seeing movies he…
18. Vogue Theatre
3290 Sacramento StSan Francisco, CA 94115
From Business: Screen Count: 1
19. Off-Market Theater
965 Mission StSan Francisco, CA 94103
20. eightCinematic
1459 Clayton StSan Francisco, CA 94114
From Business: Screen Count: 1
21. Foreign CinemaMenu
Knock on wood I've been almost a dozen times and have yet to have a bad experience. They make it look so easy! My only complaint is that it is a lit…
22. Roxie Cinema
I belive five star is a stamdard of good ranlk
23. Cinemark San Francisco 9
865 Market St # 502San Francisco, CA 94103
From Business: 6 - 10 Screens
24. Asian American Theater Co - CLOSED
690 5th St # 211San Francisco, CA 94107
25. Flying Actor Studio
40 1st St # 300San Francisco, CA 94105
26. Actors Theatre
855 Bush StSan Francisco, CA 94108
27. Sundance Kabuki
After sifting through many movie theatre reviews we chose the Sundance Kabuki Cinema in Japantown mostly because it gave us the choice to choose our…
28. Melzer Bill - CLOSED
730 11th AveSan Francisco, CA 94118
29. San Francisco Theater Festival
21 Columbus AveSan Francisco, CA 94111
30. Peerless Entertainment
3290 Sacramento StSan Francisco, CA 94115
Great deal NOW- all films at all times at $3.50 thats right -They are now playing what I would call second run films. Those that have been released to the public and now are at the end of thier run- if you can wait go see it here and Tuesday nights are $2.00 popcorn night ...more! view less
Saw Connie Francis here last year. It's still a grand old theater. I hope she's still around when I'm old. The only minus is the parking -- very difficult to find in the Castro/Market Street area.


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Virulence factors are molecules expressed and secreted by pathogens (bacteria, viruses, fungi and protozoa) that enable them to achieve the following:
* colonization of a niche in the host (this includes adhesion to cells)
* Immunoevasion, evasion of the host's immune response
* Immunosuppression, inhibition of the host's immune response
* entry into and exit out of cells (if the pathogen is an intracellular one)
* obtain nutrition from the host.
Virulence factors are very often responsible for causing disease in the host as they inhibit certain host functions.
Adherence Factors: Many pathogenic bacteria colonize mucosal sites by using pili (fimbriae) to adhere to cells.
Invasion Factors: Surface components that allow the bacterium to invade host cells can be encoded on plasmids, but more often are on the chromosome.
Capsules: Many bacteria are surrounded by capsules that protect them from opsonization and phagocytosis.
Endotoxins: The lipopolysaccharide endotoxins on Gram-negative bacteria cause fever, changes in blood pressure, inflammation, lethal shock, and many other toxic events.
Exotoxins: Exotoxins include several types of protein toxins and enzymes produced and/or secreted from pathogenic bacteria. Major categories include cytotoxins, neurotoxins, and enterotoxins.
Siderophores: Siderophores are iron-binding factors that allow some bacteria to compete with the host for iron, which is bound to hemoglobin, transferrin, and lactoferrin.
Source; NCBI
The roles of the zinc finger transcription factors XlnR, ClrA and ClrB in the breakdown of lignocellulose by Aspergillus niger.
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Change Factors in Group Therapy: Development and Validation of a Questionnaire.
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Walking beyond preferred transition speed increases muscle activations with a shift from inverted pendulum to spring mass model in lower extremity.
The triggers for the transition of gait from walking to running during increasing speed locomotion have been attributed to an energy conservation strategy or a relief of excessive muscle activation. W...
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Mandibular retrognathism may be the result of a developmental abnormality or the unfavorable positional relationship of developing jaws. Several lines of evidence suggest that muscles are known to hav...
The prevalence of celiac disease in patients with geographic tongue.
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Scientists double number of known genetic risk factors for endometrial cancer
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ZURICH, May 3 (Reuters) - The Swiss blue-chip SMI was seen opening flat at 7,976 points on Tuesday, according to premarket indications by bank Julius Baer.
NORDIC STOCKS - Factors to watch on May 3
The following stocks may be affected by newspaper reports and other factors on Tuesday:
Swiss stocks - Factors to watch on May 3
ZURICH, May 3 (Reuters) - The following are some of the main factors expected to affect Swiss stocks on Tuesday:
German stocks - Factors to watch on May 3
BERLIN/FRANKFURT, May 3 (Reuters) - The following are some of the factors that may move German stocks on Tuesday:
PharmaRoth Labs Announces Integration of HSBC Credit Facilities
LAS VEGAS, NV -- (Marketwired) -- 05/03/16 -- PharmaRoth Labs, Inc. (OTC PINK: ROTH), the exclusive producer, marketer, and distributor of Sucanon®, an oral Type-II Diabetes treatment, today announc...
Global RNA recognition patterns of post-transcriptional regulators Hfq and CsrA revealed by UV crosslinking in vivo
The molecular roles of many RNA-binding proteins in bacterial post-transcriptional gene regulation are not well understood. Approaches combining in vivo UV crosslinking with RNA deep sequencing (...
Elucidating the DDK-dependent step in replication initiation
By phosphorylating specific replication factors, cell cycle kinases ensure that eukaryotic DNA replication is initiated once and only once per mitotic cell division. New work in The EMBO Journal now r...
Telephus Medical, located in San Diego, California, is developing a suite of monoclonal antibody products designed to neutralize key staphylococcal enzymes used to attach to host ...
Design SHIFT is a Menlo Park-based product design firm founded in 2009 with the simple idea that with passion and focus, small teams can deliver breakthrough products on a global ...
Integra ServiceConnect® connects people to services they need to improve their health. With the recognition that 80% of health outcomes are driven by non-clinical social factor...
Conceivable is the first modern fertility program that radically improves a womanâs natural ability to get and stay pregnant. The Conceivable program helps women identify, un...
Tenet Healthcare Corporation and Health Net, Inc.
This release contains âforward-looking statementsâ â that is, statements that relate to future, not past, events. In this context, forward-looking statements often ...
N of One: Autism Research Foundation
N of One: Autism Research Foundation was founded in 2014, with a mission to facilitate and sponsor breakthrough autism medical research. N of One emphasizes research that treats t...
Stemedica Cell Technologies, Inc.
Stemedica Cell Technologies, Inc. (www.stemedica.com) is a specialty biopharmaceutical company that is committed to the development and manufacturing of best-in-class adult stem cells and stem cell fa...
Founded in Epalinges, Switzerland, in 2008, Stemedica International S.A. is a global biotechnology company that develops therapeutic applications for the treatment and prevention ...
Angiocrine Bioscience is a privately held biotech company focused on applying vascular biology to new therapeutic applications. Angiocrineâs VeraVecTM technology platform is ...
Ocugen is advancing novel biologicals discovered based on endogenous proteins with well understood biology at the molecular, cellular, and whole animal level to treat eye diseases...
Early Detection of Lung Cancer With Low-dose Multislice Computed Tomography
Lung cancer is one of the leading causes of cancer-related death in Taiwan. Early diagnosis of lung cancer may improve cancer survival. Low-dose computed tomography (LDCT) was thought to b...
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This study takes place in rural Mam-Mayan communities of Guatemala characterized by high rates of childhood stunting. It aims to characterize women's exposure to nutrition, infection and p...
Severe Male Factor Infertility Management
This study is the first to evaluate the effect of oral supplementation with antioxidants combined with lifestyle modification for severe male factor partners of couples undergoing ICSI.
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Along with the improvement of living standard, the prevalence of Lower extremity arterial occlusive disease (LEAOD) is also increasing, which has become an important cause of lower extremi...
Predicting Severe Toxicity of Targeted Therapies in Elderly Patients With Cancer
In order to assess the important issue of the safety of antiangiogenic TKI in geriatric population we set up this project which aims to identify, among clinical, biological, pharmacokineti...
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This single-center, cross-sectional survey and sensory examination is conducted to determine the prevalence, sensory characteristics and risk factors of PPSP in patients who underwent cyst...
The Effect of Vitamin D Supplementation on Cardiovascular Risk Factors
Six-hundred subjects with vitamin D deficiency will be randomized to vitamin D 3000 IU per day versus placebo for 4 months, with effects on cardiovascular risk factors as main endpoint
This is a naturalistic study of 100 migraineurs and 75 post concussive headache patients who will be asked to record their headaches, medications, sleep and other behaviors in a smartphone...
Risk Factors Related to Metabolic Syndrome in School-aged Children Who Were Born Preterm
This is a follow-up cohort study of 8 years old children born preterm at Seoul National University Children's Hospital in Korea from 2008-2009. The children will visit outpatient clinics ...
The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.
Pertussis Toxin
One of the virulence factors produced by BORDETELLA PERTUSSIS. It is a multimeric protein composed of five subunits S1 - S5. S1 contains mono ADPribose transferase activity.
Adenylate Cyclase Toxin
One of the virulence factors produced by virulent BORDETELLA organisms. It is a bifunctional protein with both ADENYLATE CYCLASE and hemolysin components.
Catheter-related Infections
Infections resulting from the use of catheters. Proper aseptic technique, site of catheter placement, material composition, and virulence of the organism are all factors that can influence possible infection.
Virulence Factors
Those components of an organism that determine its capacity to cause disease but are not required for its viability per se. Two classes have been characterized: TOXINS, BIOLOGICAL and surface adhesion molecules that effect the ability of the microorganism to invade and colonize a host. (From Davis et al., Microbiology, 4th ed. p486)
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Women's Health - key topics include breast cancer, pregnancy, menopause, stroke Follow and track Women's Health News on BioPortfolio: Women's Health News RSS Women'...
Bioinformatics is the application of computer software and hardware to the management of biological data to create useful information. Computers are used to gather, store, analyze and integrate biological and genetic information which can then be applied...
Within medicine, nutrition (the study of food and the effect of its components on the body) has many different roles. Appropriate nutrition can help prevent certain diseases, or treat others. In critically ill patients, artificial feeding by tubes need t...