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San Diego CA Real Estate & Homes for Sale
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Courtesy: Coldwell Banker Res. Brokerage Saied Mojabi
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Two buildings on one lot. Original house of 915 Sqft plus a permitted 588 square feet two story studio built in 2006 by award winning architect Petar Perisic designed and built around the tree! This artists retreat has two levels.The lower level has a bathroom & is large enough for any home/consulting/storage business or just a huge studio . Upstairs has an office w/tall ceilings and balcony overlooking a serene canyon great for a painter writer or someone who needs a space for meditation.
$180,000 - $195,000
3677 41 Street UNIT 7 San Diego, CA 92105
Courtesy: Del Rancho Realty, Inc Juan Rodriguez
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Back on the market 03/21/2016. Up and coming area!!Short Sale VERY CLEAN UNIT WITH ONE CAR GARAGE PLUS SPACE. SHOWS WELL. Agents please see confidential remarks.
Courtesy: Ascent Real Estate, Inc Brian Lacklen
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Enjoy this completely remodeled piece of heaven in Fox Canyon! This condo has been tastefully modernized to include new cabinets quartz countertops vanity stainless steel appliances range hood backsplash washer/dryer windows/slider painting flooring ceiling fans electrical upgrade etc. Nestled away yet in the heart of the city; this private location is ideal and ready for the turnkey buyer. This top floor unit comes with a large balcony overlooking the canyon with morning sun.
$280,000 - $300,000
3785 47th San Diego, CA 92105
Courtesy: HomeSmart Realty West Chirag Mehta
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Darling cottage in the heart of San Diego! This home features new tile in the kitchen and bathroom new shower enclosure in the bathroom new windows new sliding glass door new deck on the side of the house the driveway and patio had new concrete poured update appliance New painted inside and out new insulation in the attic granite countertop new sink in the kitchen new cabinets and tankless water heater. Close to all shopping center and freeway. Hurry This home Will not Last Long!
$324,000 - $349,000
4317 Dwight San Diego, CA 92105
Courtesy: First Legacy Fncl. Grp, Inc. Richard Trefflich
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Beautiful completely remodeled cozy home in City Heights. Features include new roof paint kitchen with granite counter tops and stainless steel appliances flooring just to name a few.
Courtesy: Keller Williams Realty Debbie Jacobs
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This manufactured home has 2bed/2bath & is over 960 sq. ft..There are (2)huge bedrooms & 2 large walk-in closets... Only 7 minutes from downtown San Diego.. Bayview Mobile Estates is a family park...Refrigerator range & microwave are included in the sale...Some years ago the kitchen was updated...There is newer galvanized plumbing a new furnace & hot water heater...Seller is offering $1000 carpet allowance. New piers jacks & pads were replaced underneath the home & 2 new sets of stairs were built
$348,000 - $359,000
5229 Wightman San Diego, CA 92105
Courtesy: Initiative Real Estate, Inc. Brenda Bermudez-Sommerma
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Location Location...Cute remodeled home with a large yard and space for boat or RV parking. Some of the features of this lovely home include granite counters; hardwood floors; laundry room; nicely appointed master bedroom and bath with walk in closet. Newer roof and water heater.
4180 39th UNIT 9 San Diego, CA 92105
Courtesy: Keller Williams Realty Ti Cason-Davis
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Priced at $205000 1 CAR GARAGE PLUS 1 ASSIGNED SPACE Updated flooring throughout updated bathroom and spacious bedroom with walk-in closet. Five minute walk from local park. Tenant will stay at investors request. Condo is located in the up-and-coming Corridor neighborhood. Situated between Kensington and South Park with North Park to its West. Area improvements are just beginning...get in on this great opportunity before prices jump. RENOVATION FINANCING AVAILABLE.
Courtesy: Dwell Well Realty Mike Acker
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Affordable Clean Ugraded Top-floor Condo in GREAT walkable neighborhood immediately adjacent to Kensington at Meade Ave. 2 covered parking spaces in attached carport plus storage space! This bright and airy end unit is the only 2 bedroom unit in complex and the only unit with a beautiful working gas fireplace with original 1970s stone facade preserved. HOA pays for gas to operate fireplace! Community laundry is right below unit located and is free of charge.
2866 39th St San Diego, CA 92105
Courtesy: AAAE Realty & Home Loans Lauren Nguyen
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Ideal for a starter or an investor. Three bedrooms and two bath with a good size living room. Two bath rooms and the kitchen were just renovated. Nice and new. Located at the end of the street. Zone 2 and there is a storage room in the back of the house which can be permitted to build the second unit. Seller is very motivated price was reduced
$345,000 - $365,000
2317 Shamrock Street San Diego, CA 92105
Courtesy: Horizon Real Estate Kim Ward
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Spacious top floor condo has balconies with breathtaking views in lovely Azalea Park. Watch the beautiful San Diego sunset or enjoy the open green space of Hollywood Park to the east. This is not your typical condo; there are only three units in the building and they share a large common yard. Nice architectural details including arched doorways and tile flooring. The master bathroom has a walk-in closet. Open concept living/dining room and kitchen. Two-car garage with laundry hookups.
2631 Balsa San Diego, CA 92105
Courtesy: David T. Mejia Lorena Vasquez
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Great family home half block from elementary school close to stores nice back yard with fruit trees perfect for entertaining.
3350 54th San Diego, CA 92105
Courtesy: Doug Ross Real Estate Doug Ross
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Price Reduced Fire Your Landlord ------ Become a Home Owner Now! Beautifully remodeled move-in ready centrally located. Lovely gated front courtyard w/ high hedges for privacy. Open floor plan. New laminate flooring and carpet. Kitchen has brand new stainless appliances granite counters & rich wood cabinets. Double pane low-e Windows and Sliders. Fully permitted 2nd bathroom w/ sleek tiling motion light sensor and humidity sensor switches.
Courtesy: Berkshire Hathaway HomeService Joel Blumenfeld
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Great investment opportunity to own in this centrally located gated complex 1BR/1BA upstairs corner-unit featuring newer hand-scraped wood flooring tiled shower/bathtub dual-pane windows pedestal sink & walk-in closet. All appliances convey. Complex has laundry room. Located near SDSU parks schools public transportation and more. Tenant occupied - Lease runs until 12/1.
4117 Sycamore San Diego, CA 92105
Courtesy: Cramer Consulting Group John Cramer
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Fixer home is in need of a remodel. Perfect for an investor or first time home owner. FHA 203k or conventional renovation financing available. Lot is zoned for 2 units currently and potentially can be split and have the 2nd home built on the proposed legal lot or a 2 unit can be added with current zoning status with applicable permits and fees. Seller is not willing to do any repairs or upgrades to the property.
$399,000 - $439,000
2536 52nd Street San Diego, CA 92105
Courtesy: AAAE Realty & Home Loans Lauren Nguyen
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BOM. The house located in the heart of Oak Park looking over to a beautiful park. House is in good conditions ready to move in. Owner had remodeled the whole house. Garage was converted into a family room and a master bedroom (Permits unknown) but the owner has renovated it and it looks nice and new. Recessed lights in the living room. Brand new kitchen with granite counter top new cabinets and stainless steel appliances. Wall AC in the master bedroom. A huge back yard with a lot of potential.
$299,900 - $349,900
2624 46th San Diego, CA 92105
Courtesy: BHGRE McMillin Realty Patti McKelvey
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Courtesy: Melissa Goldstein Tucci Melissa Goldstein Tucci
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Unique opportunity to own a Mixed Use property in a desireable central location! This property has a huge workshop in the back with alley entrance access for private secure parking.Ideal for store front mechanics machine shop or can be used as single family residence! Possibilities are endless! Traditional sale!
2842 39th UNIT 4 San Diego, CA 92105
Courtesy: Cal State Realty Services Ali Pourrastegar
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Top floor corner unit with laminate and tile flooring. Kitchen with granite counters. Renovated two years ago. Newer dual-pane vinyl windows allow plenty of light while keeping out noise. Close to freeways and minutes to North Park with your own parking space!
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MUMBAI Dec 14 Indian fertiliser shares rallied on Friday after the government approved a new policy to encourage investment in urea manufacturing, in a move seen expediting $6.5 billion in projects that have been held back.
National Fertilizers was up 5.3 percent at 0351 GMT, Rashtriya Chemicals and Fertilizers gained 5.2 percent, while Chambal Fertilisers and Chemicals gained 2.9 percent. For story, see (Reporting by Rafael Nam; Editing by Prateek Chatterjee)
Trending On Reuters
Uber vs Ola
How fight for Indian taxi market ended up in court
A flurry of complaints from Uber drivers about an unusually high number of cancelled bookings was the spark that ignited a bitter legal fight with Ola, Uber's rival for dominance of India's $12 billion taxi market, according to court documents and a source with direct knowledge of Uber's case. Article
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subset: commoncrawl


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Support PDF,DOC,DOCX,TXT,XLS,WPD,HTM,HTML fils up to 5MB
Your career is too important to spend your time looking for a job on a variety of sites. If you were sick you would find the best possible doctor. You should do the same thing with your job site. There is no better job board in the world for legal professionals: LawCrossing shows you jobs from every single employer career page, job website, association website
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StartUpHire is the place to find Software Test Engineer (API and UI) jobs. Review the list of Software Test Engineer (API and UI) career opportunities to the left. These Software Test Engineer (API and UI) jobs represent some of the most rewarding careers available.
You can refine your job search for Software Test Engineer (API and UI) career opportunities by adding a job title, company name, or keyword to the search box above … or click the "Advanced Search" link for more options.
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HOURS: Full time, 40 hours Employer: Akana Jobsite: 12100 Wilshire Blvd, Suite 1800, Los Angeles, CA 90025 Job Duties: Key contributor in building out the latest and greatest technologies for QA testing with an automation-first approach. Work with various2/29/2016 Los Angeles, CA Save This Job
DEPARTMENT Engineering CITY Irvine, CA TYPE Full-Time What you?ll do As a Senior Software Quality Engineer, you will be responsible for embedding quality throughout the software development and product engineering process by engaging with various departments including product3/8/2016 Irvine, CA Save This Job
Technology Mountain View, CA, United States xAd enables real-time, location-based marketing, without the guesswork. Working with xAd, marketers can deliver more relevant, personalized messages to the right people they want to reach, based on the real places they visit everyday.3/31/2016 Mountain View, CA Save This Job
ID 2016-2139 Job Location US-WA-Seattle Posted Date 2/19/2016 More information about this job: Overview: At Accolade, we?re transforming the way people experience healthcare. We believe that conventional approaches are failing American families, and reject the notion that4/19/2016 Seattle, WA Save This Job
HOURS: Full time, 40 hours Employer: Akana Jobsite: 12100 Wilshire Blvd, Suite 1800, Los Angeles, CA 90025 Job Duties: Test the code written by the UI Development team Write test automation using Selenium/Webdriver Develop test automation in parallel with the2/29/2016 Los Angeles, CA Save This Job
Location: Burlington, MA The Senior QA Engineer is responsible for creating and maintaining test plans and test cases, executing formal test plans, and implementing API based regression and performance tests. This position reports to the QA Director. The ideal candidate has2/29/2016 Burlington, MA Save This Job
Location:Boston, MA Job Code:567 # of Openings:1 Description Software Engineer in Test Data Xu seeks a highly motivated software and test engineer to drive the development of advanced test automation for our media decision platform for online advertising. This is an3/2/2016 Boston, MA Save This Job
Req No. REQ109825 Location US-CA-San Francisco Category Information Technology More information about this job: Job Description: Senior QA Automation & Whitebox Test Engineer Location: San Francisco, CA Job Overview ServiceSource International is looking for a Software3/6/2016 San Francisco, CA Save This Job
Tracking Code 2041 Job Description Silver Spring Networks is looking for a Senior Java Engineer to extend our technology leadership in enabling the Smart Grid and the Internet of Things. In this role, you will be responsible for building the core Network Management software2/22/2016 Redwood City, CA Save This Job
Emeryville, CA We are searching for a Sr. Software Engineer to be a part of our overall UI software testing efforts. You will be responsible for verifying different aspects of our ad platform, with a mixture of functional verification and automated test development for the UI2/29/2016 Emeryville, CA Save This Job
Posted: February 1st 2016 The Senior QA Engineer will be a member of a test automation team that is responsible for creating reusable test software aimed to improve functional test coverage, schedule efficiency and reduce manual test dependency. The person filling this position3/15/2016 San Francisco, CA Save This Job
JOB DESCRIPTION: Are you looking for an exciting well-funded, privately-held post start-up opportunity? Do you have experience testing software solutions for the healthcare market? Are you interested in joining a fast growing software company delivering enterprise patient care3/30/2016 Bedford, MA Save This Job
Position Summary Genocea is initiating a project to build a software platform to automate its proprietary vaccine discovery workflows and capture row data and results into a central database to build a data warehouse for data mining and analysis. For this project we are seeking a3/23/2016 Cambridge, MA Save This Job
Job Locations US-NY-New York Category Internship Travel None Level Individual Contributor More information about this job: Overview: One of the largest drivers of growth in our industry is the transition of traditional media into the digital space. MediaMath prides ourselves3/13/2016 New York, NY Save This Job
Job ID 2016-3342 Job Location US-TX-Austin Category Engineering Type Full-Time More information about this job About Bazaarvoice Bazaarvoice is a network that connects brands and retailers to the authentic voices of people where they shop. Each month, more than 500 million4/13/2016 Austin, TX Save This Job
Plastiq (pronounced "Plastic") is a fast-growing tech company changing the landscape of payments, empowering you to use your cards everywhere cards aren?t accepted. Starting with a vision to drive new payment choice for tuition, Plastiq has evolved into a service enabling3/12/2016 San Francisco, CA Save This Job
JUL 21 Full TimeSanta Monica, CAPosted 5 months ago Whipclip WebsitewhipclipWhipclip How many times have you watched something amazing on TV, had a friend in mind and thought ?Did you see this?? We are building an exciting new way to do just that, clip and share the best moments3/1/2016 Santa Monica, CA Save This Job
Chicago Who We Are Opternative is a healthcare technology company building something bigger than a great application; our team has created the online eye exam that science never thought possible. Opternative is looking for more than just skilled and talented individuals. We are4/20/2016 Chicago, IL Save This Job
Quality Assurance Seattle, WA, United States As a SDET2 with NetMotion Wireless, you will use your technical expertise to create, port, and maintain automation in C# and SQL; use automation tools including Selenium, and SOAP based interfaces. This automation will support high4/6/2016 Seattle, WA Save This Job


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Vellore Adithi News
Amazing Adventures in Undergrad ResearchMay 15, 2013
Vellore Adithi loves comic books. Growing up, the Missouri native remembers travelling to India during the summer to visit her family and voraciously reading Archie, Tin Tin, Asterix and Batman. Adithi, a USC Dornsife…
Finding Their MuseApril 29, 2013
When Eric Weintraub's name was announced as first place winner for his short story "La Laguna" at USC's 2013 Undergraduate Writers' Conference, he turned to the student next to him, "Did they just say…
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- In Memoriam: Robert Bils, 85 April 22, 2016
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- USC Dornsife student Shea Rouda develops philanthropic startup April 21, 2016
- USC Dornsife's Everett and St. John elected to the American Academy of Arts and Sciences April 20, 2016
- Frontline Scholar: Justin April 20, 2016


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'I accept that the comments that Ken Livingstone has made make it more difficult for Londoners of Jewish faith to feel that the Labour Party is a place for them,' says mayoral candidate Sadiq Khan.03:33 02.05.16 | 0 comments
Excellent news here. Give him to Germany and I hope they put him away for a decade. A message to Mossad and their arrogant superiors. Your put at risk the citizens of a foreign country by forging the passports of that country. Serous enough crime I believe to put Netanyahu on a most wanted list.


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0521794404 / 978-0521794404 / Financial Markets and European Monetary Cooperation: The Lessons of the 1992-93 Exchange Rate Mechanism Crisis (Japan-US Center UFJ Bank Monographs on International Financial Markets) / Willem H. Buiter, Giancarlo Corsetti, Paolo A. Pesenti
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Geoffrey RogersShared publicly -
Some ppl are just fucking crazy, how u gonna pull a box cutter out on someone who is videoing u? I'm guessing he's not the brightest bulb in the house
A road rage victim's cell phone video was key in arresting the suspect who allegedly smashed her window.
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LMG custom-engineered HD-1, which provides all of the capabilities of a mobile truck in easily shipped containers. As the system's centerpiece, the Kahuna switcher allows HD-1 technicians to intermix HD and SD sources in the same switching system.
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Federal Funding May Be First And Last Resort For Cleantech
Venture capitalists investing in clean technology are closely watching a number of possible government funding sources that could replenish the later-stage capital that has largely evaporated.
"The biggest impact [on cleantech] is the overall financial situation in terms of availability or lack of availability of debt, tax equity, project finance money, later-stage private equity or hedge funds," said Stephan Dolezalek, managing director and head of the cleantech practice at VantagePoint Venture Partners. "Really everything past the venture stage has largely disappeared. It'll take time to come back."
Dolezalek was speaking alongside several other investors in a panel that kicked off the Dow Jones Alternative Energy Innovations conference, which is running today and tomorrow in Redwood City, Calif.
Josh Green, general partner at Mohr Davidow Ventures, said the cleantech industry will benefit from the federal funding allocated by the loan guarantee program, the stimulus bill, and a clean-energy bill that is being considered now. But the exact form all this funding will take is still unclear. He is hoping for a some kind of venture debt program.
"I'm hopeful as a VC who's protective of the capitalization table that it's a debt instrument we end up with," Green said. "Something akin to a super large venture lending instrument where someone takes a higher than normal interest rate with warrant protection and would not destroy the cap table. It's proven that that's something that does pay back investors. The government plays a very important role in the next year or two in that financing gap being filled."
This situation has also changed the role for venture capitalists, who have been dealing much more often with government agencies and politicians – something that would previously be on the bottom of many to-do lists.
"We were conscious in the past to avoid being in the position where you to have to deal with government agencies, for obvious reasons," said Paul Holland, general partner, Foundation Capital. "But in the last eight to ten weeks we had more government interaction – mostly federal – than we've had in seven years prior."
While many firms had at most a vice president of government relations, now many partners have interaction with government on a day-to-day basis.
"Government has become the loaner of last resort and the loaner of first resort for certain cases of financing," Holland said. "Anyone with significant capital requirements going forward…has got to find other sources [of capital]. Right now the government is providing that."
On Tuesday, several groups of venture capital angel investors launched a network to bridge the gap between the "friends and family" funding and later-stage institutional investors.
Partners at Kuwait Petroleum Energy Ventures Inc., CalCEF Clean Energy Angel Fund, and Keiretsu Forum's Cleantech Investment Committee formed a non-binding partnership "to bring together angel investors to exchange deal flow information, improve clean-tech education, and create a bridge between clean-tech entrepreneurs and early-stage investors," the investors said in a statement.
With the strong growth in venture capital investments in clean technology and renewable energy in recent years, and the refocused attention on investment in these areas by the U.S. government, the group said it decided to create a "network of networks" to increase collaboration among investors to increase the chance of promising technologies being funded.
La Jolla, Calif.-based PCG Asset Management, which has invested in CalCEF angel fund and also provided clean technology advisory services for Kuwait Petroleum Energy Ventures, is supporting the new initiative.
"From PCGAM's perspective, the way technology evolves, there has been this gap from the financial and operational support; this is attempting to fill that gap to bring together the capital to commercialize the idea," said Erin I-Ping Kuo, investor relations for the clean technology group at PCG Asset Management.
-With reporting by Mara Lemos Stein


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The new Tucson is a crucial model for Hyundai as it renews its attack on the crossover class, but is it as good to live with as a Nissan Qashqai?
Its twin under the skin, the Nissan Qashqai, is a sales hit, so does this distinctively styled newcomer to our fleet also have the makings of a winner? Let's see
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The fuel economy in our long-term Jaguar XE isn't great — perhaps because the XE is so much fun to drive
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It's already seen off its Mercedes-Benz and BMW rivals during a comparison test, but this junior Land Rover now begins a tougher trial: a year in our hands
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Saudi Arabia's media environment is growing more open despite changes to press laws that have been criticised as restrictive by international rights groups, the prince who runs a leading pro-reform Saudi newspaper said on Sunday.
"The laws with respect to media have been in evolution for the past 40-odd years and just in the 10 years that I've been involved in this industry I've seen it move forward tremendously," Prince Bandar bin Khaled al-Faisal, who is chairman of the daily Al Watan newspaper, said.
Watan is seen by analysts as being towards the progressive end of the kingdom's media spectrum, featuring editorials that broadly support economic and social reforms pushed by King Abdullah and sometimes challenge conservative thinking.
Amnesty International said last week in a report that the world's top oil exporter was cracking down on freedom of expression in the wake of uprisings across the Arab world.
The report cited changes announced in April, when state news agency SPA reported that publications that jeopardised national stability or offended clerics faced fines or even closure under a royal decree.
"The media is severely constrained and those who express dissent face arrest and imprisonment, whether political critics, bloggers or academics," said the report, which also criticised a draft of an anti-terrorism law leaked to the press in June.
The Saudi embassy in London said Amnesty's report was based on inaccurate information.
A 2009 US diplomatic cable released by WikiLeaks said the kingdom's press had grown steadily bolder over the past decade, thanks partly to Abdullah's efforts to push media owners to report more openly on social issues.
Prince Bandar, a son of the governor of Mecca Province and a great-nephew of King Abdullah, said he believed there was no campaign under way to clamp down on media.
"What you need to focus on is what is approved and what is implemented. And if you look at the track record over the past four or so decades, every single (change) that comes in has been a refinement in my point of view that has been positive," he told Reuters in Dubai.
"I have no reason to suspect it would go in any other direction and, honestly, you can't take it in any other direction."
Disclaimer:The view expressed here by our readers are not necessarily shared by Arabian Business, its employees, sponsors or its advertisers.
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text: Analysis Focus: Flexible Working – Now you see me… By The Lawyer 31 January 2010 00:00 17 December 2015 09:37 Sign in or register to continue reading. It's FREE Sign in Email Password Keep me logged in Forgot your password? Not registered? It's FREE! Register now Register with The Lawyer Anonymous 2 February 2010 at 15:33 Clare Maurice provides a few words of advice to female solicitors who want to juggle work and a family. Apparently one of the top tips is to be heterosexual: "If you want a family choose your partner with great care – he must be prepared to share all the responsibilities of parenthood….". Reply Link Name Email Cancel reply Threaded commenting powered by interconnect/it code.


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The top 10 schools for a degree in applied mathematics
This is one of the higher paying majors in the mathematics field.
This is one of the higher paying majors in the mathematics field.
There's a lot to familiarize yourself with — the guide can help.
Looking for a major that practically guarantees a great paycheck upon graduation?
Public health degree majors become leaders who take steps towards managing global health risks.
Great salespeople, brilliant inventors and charismatic leaders are powerless if they can't communicate and organize data.
The rankings are based on athletic competitiveness, academic quality, return on investment and leadership.
These schools are rigorous and have a strong focus on preparing students for a successful career beyond the classroom.
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Yael Patir, Israel director of the left-leaning U.S. Jewish body, sat down with Haaretz to talk about Trump, the gap between U.S. and Israeli Jews, and the growing anger at the Israeli peace camp. Though she concedes boycott efforts by some on the left have a negative effect, she rejects calls to keep peace efforts local.01:12 01.05.16 | 1 comments
Israel changed the rules of the game after the settlers were murdered, which is what started this escalation of exchanges. It needs to ease back a bit - NOT escalate it further with a so call surprise blow. There IS no such thing as the last word!
from the article: Gaza is presenting Netanyahu with the toughest test of his term


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August 27, 2011; Englewood, CO, USA; Seattle Seahawks head coach Pete Carroll hugs Denver Broncos head coach John Fox following the end of the game at Sports Authority Field. The Broncos defeated the Seahawks 23-20. Mandatory Credit: Ron Chenoy-US PRESSWIRE
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Leicester City are just one win away from making Premier League history
You've probably heard by now about Leicester City, the little English club that was almost relegated last year was a 5,000/1 (…)
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Floyd Mayweather says he might come out of retirement for a monster payday
Floyd Mayweather is the best boxer of his era, but all the signs recently have suggested that the Mayweather Era is well and truly (…)
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President Obama channels Kobe to end speech, drops mic and says 'Obama out'
He dropped the mic.
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Penguins' Olli Maatta gets laid out with a high hit to the head from Capitals' Orpik
Late and high.


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Spirit FM News
Local News headlines - Page 8
Football Tribute To Brighton Fan
Supporters will pay their respects to the Brighton fan tonight, who died after Friday's win over Fulham.
Sussex PC Reveals Assault Horror
A series of tweets has detailed an eventful night for one Sussex police officer at the weekend
'Dramatically' Fewer Travellers In Adur & Worthing
There are 'dramatically fewer travellers in Adur and Worthing, according to the councils.
VIDEO: 'Island' Doctor Left In Shock
A Chichester doctor who's starring in The Island with Bear Grylls has spoken of the moment he saw a fellow campmate fall off the side of a cliff.
Beloved Cat Shot Dead In Sidlesham
A family's distraught after discovering their cat shot dead in Sidlesham.
Cash Boost To Fix West Sussex Walkways
West Sussex County Council has committed to spending £5m on repairing footways and pavements across the county over the next two years.
Henfield Man 'Embarrassed' Living With Parkinson's
A West Sussex man has opened up about life living with Parkinson's.
More Controlled Parking In East Worthing
More people in East Worthing could be getting double yellow lines outside their homes.
VIDEO: It's Official - Spring Is On Hold
Forecasters say we should expect a colder start than usual to May, with wintry showers (Brrr)
VIDEO: Police Hunt for Three After Bracklesham Bay Robbery
Police have issued a video of three people they want to want to speak to in relation to a robbery in Bracklesham Bay.
Conductors To Enter Talks With Southern
Talks aimed at averting further strikes by Southern Railway conductors are to be held on Friday, according to union bosses (29th April).
Services To Be Affected By Southern Rail Strike
Conductors on Southern Railway will be walking out today in a dispute over the introduction of Driver Only Operation (Tuesday 25th).


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Welcome to ABC Radio National. Skip to:
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Saturday 10.05am Repeated: Sunday 06.05am
A gardening show with a twist. Talking Plants is a witty and at times provocative discussion show on all things botanical. It provides a platform for informed discussion about plants, gardens, landscape design and other botanical matters - the show incorporates science, the environment, health and art, but offers much more besides.
Friday 5:30pm Repeated: Sunday 11am
Common Knowledge (renamed The List in 2013) unpacks new ideas, trends and obsessions with a smart, discursive and sometimes cheeky look at the zeitgeist.
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In a world marked by wicked social problems, The Minefield helps you negotiate the ethical dilemmas, contradictory claims and unacknowledged complicities of modern life.
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Join RN Breakfast's Fran Kelly and RN Drive's Patricia Karvelas as they discuss the winners, losers, voter issues and all the gossip straight from the corridors of Parliament House.
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...Having majored in Physics in college, I have used many levels of math on an everyday basis, but none more so than Algebra. Algebra 2 focuses on refining math techniques and skills, which I have helped many students do in their coursework in Physics. I have also worked with students in Algebra-l...
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Reviews - Holiday Inn Express BURNLEY M65, JCT.103
55 Pendle Way, Burnley, BB12 0TJ
Price From £65View Rooms
Customer Reviews
Our reviews are from genuine LateRooms.com customers. We verify that the customer has stayed before leaving a review.
Very Good
81% would recommend it to a friend
Customer service
Food quality
Room quality
Holiday Inn Express BURNLEY M65, JCT.10
Very friendly staff and very.
Very surprised
After reading so many negative comments about the hotel I was wary.
I was so wrong. Hotel is excellent. Good food and plentiful. Only ate breakfast following morning. Reception desk very helpful and great idea to pick up a phone for local taxi. Room was clean and very homely.
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Good night sleep
Overall a pleasant stay.
Room was a good standard. clean and well presented. Food ok.
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Grandson starting UCFB
Staff pleasant,room clean and fresh,hairdryer not working,sofa bed extremly uncomfortable,only two cups for three guests.
Response from hotel
Dear Mary Y,
Thank you for your feedback and for staying with us. We realize you have many choices when it comes to lodging, and we sincerely appreciate your business with us. We are very happy to read your positive feedback on the cleanliness of the room received and the pleasant service received.
However, we are truly sorry if your stay was not a complete satisfactory due to the inconvenience the sofa bed and hair dryer may have caused you.
We take all of the reviews we receive very seriously as they allow us to identify areas that may benefit from additional attention. Rest assured that these will be addressed immediately to the hotel management for review to achieve complete guest satisfaction.
Thank you for your feedback and we hope to offer you a more pleasant stay in the future.
IHG Care
Business Stay
Very clean and appropriate accomodation.
Only negative was TV didnt work
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excellent staff
Very friendly and welcoming staff.
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Dear V Pavlova,
Thank you for writing a review about our property. We strive to give great and impressive service to all of our guests. It makes us happy to read we have met your expectations and that our location and amenities were suitable to your needs. We look forward to welcoming you back to our establishment. Once again thank you for the wonderful comments and kind words of praise for our staff.
IHG Care
Clean and efficient
Holiday Inn Express Burnley M65, Jct.10
Staff were friendly & helpful.
The room was nice & clean. Good value for money.
Read More Less
Great service and staff
I had not stayed in the area before and Andy could not not have been a greater help obtaining information re: travel times etc which took away a lot of the pressure.
All staff were a big help and very well mannered
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Not Great
Not enough staff working in Hotel, makes waiting for a drink or something to eat a trial, i honestly wouldn`t stay here again.
Response from hotel
Dear G Lowrie,
Thank you very much for staying with us and writing a review. Our hotel is very proud of its level of service, cleanliness and quality of product. I am sorry to hear about the slow service you received during your stay. Please accept our sincere apologies for any inconvenience it may have caused you. We take all reviews very seriously and your feedback will help us improve for our next guest or your next visit.
We value you as our guest and hope you will continue to choose IHG for your future travel needs.
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Getting Old With a Sense of Humor
2 Responses to "Getting Old With a Sense of Humor"
Kim says:
Oh Marty, that made my day. Thanks for posting it! All too true.
EHOB Inc says:
Hopefully other caregivers find some relief and humor from this video. Thanks for sharing!
Leave a Reply
e all know, even without reading research papers, that music has emotional benefit: it can excite and calm and induce a wonderfully cathartic weeping session. This applies whether you're healthy or sick; whether you have Parkinson's or autism or Alzheimer's.
But studies have found that music can also be of cognitive benefit: it helps people remember things better.
What exactly does this mean, and what specifically does it mean for an Alzheimer's patient? Does it mean that if you play the oldies station in the background all the time, your Mom will wake up one day and remember everything again?
Let's look at the evidence:
First of all, "music" is a pretty general term. Are we talking about singing? Playing a guitar? Listening to Mozart? Listening to Bobby McFerrin's improvisational jazz? Believe it or not, these are all different things.
According to a study reported by Time Magazine,("Music on the Brain")
Different networks of neurons are activated [in the brain], depending on whether a person is listening to music or playing an instrument, and whether or not the music involves lyrics.
In another study, quoted in Neuroscience for Kids,
researchers have recorded neuronal activity from the temporal lobe of patients undergoing brain surgery for epilepsy. During this study, awake patients heard either a song by Mozart, a folk song or the theme from "Miami Vice". These different kinds of music had different effects on the neurons in the temporal lobe.
Also, from Time'"Music on the Brain"
Experimental Audiology in Germany has shown that intensive practice of an instrument leads to discernible enlargement of parts of the cerebral cortex, the layer of gray matter most closely associated with higher brain function.
As you can see, different music affects different parts of the normal brain in different ways.
People are always studying the music-brain connection, trying to understand the mystery of it. There was a particular study done in 1993 that tried to see if music affected memory. The researchers used a song by Mozart for their experiment, and their results seemed to show that this composer's music improved test-taking. This became widely known as The Mozart Effect, and people started playing Mozart to their unborn babies thinking it would give them a head start in learning.
Though later studies failed to duplicate the Mozart Effect (perhaps the only real effect is that Mozart helps relax the body right before a test), that original research sparked further research into music-as-memory-aid. A recent study, for example, found that Alzheimer's patients can remember new information if it is sung to them much better than if it is spoken (as opposed to healthy people who can remember it equally well when sung as opposed to spoken).
We also know without reading studies that music helps trigger old memories. For example, when I hear the song "Dust in the Wind," I am immediately transported back to our family van as we drove across the country in 1977. I remember my oldest sister introducing this song to me, and how it resonated with the angst of my teenage years, etc. A whole cascade of memories brought on by a single song.
In a study reported by the Telegraph in 2009, researchers found that this recall effect is due to the fact that music is processed in the same area of the brain that forms vivid memories. They furthermore found that such memories appear to be immune to the ravages of Alzheimer's. And this could lead to a unique kind of therapy:
Because memory for autobiographically important music seems to be spared in people with Alzheimer's disease, …making a "soundtrack of someone's life" before their mind is too damaged, and playing it back to them could help form a resistance to the disease.
Love the idea! Plus I have a variation on this idea from watching this next video of Bobby McFerrin (at a conference called "Notes and Neurons"), and from observing Mom as I play the piano. First, here's Bobby:
What Bobby is doing here is getting the mind to go in a familiar direction (the pentatonic scale), then leaving an auditory blank and letting the mind fill it in. I mean, aside from jumping around, that's what he's doing. He's giving the mind a puzzle to solve. He's making the mind work. And working the mind is better than not working the mind if you want to keep it.
The next part of my idea came from playing the piano for Mom and watching her reaction. You should know Mom hasn't spoken but a few words in a couple years, and she no longer sings intelligible tunes. You should also know that I don't play the piano. I used to when I was seven, but now my playing is reduced to guessing the notes with my right hand. I can play fast enough for the tune to be recognizable. Barely. Fortunately for Mom, the tune is always a hymn—something she is very familiar with. Unfortunately for Mom, I mangle the tune. And that's where the puzzle comes in.
See, when my finger's can't find the right note, Mom gets exasperated and sings it out loud to help me find the dang thing. I'm even wondering if this puzzle-solving exercise is a factor in Mom's recent awakening.
So here is my variation on the soundtrack idea. Try this exercise (for an Alzheimer's patient) with the following video clip:
Play it once. It will probably be familiar to the listener already, but there are enough repetitions in this piece that parts of it will quickly become familiar if they aren't already. Play the video again, but pause the video every so often. There are a ton of repeated theme snippets. Pause before a theme is repeated and see if the listener is prompted to supply the missing piece. If they do, you've got a good puzzle to use.
Then, if you do this with that "Life Playlist", you should be able to double the benefit in fighting that Alzheimer's monster.
Related Posts:
Music and Caregiving—Pandora to the Rescue
Alzheimer's and Music: Stimulating the Brain into Action
Related articles:
Posit Science Blog, Your Brain on Jazz
American Music Conference, Music and the Brain
So I re-listened to the Fresh Air segment today, then did some quick digging through articles I've seen online on the brain, stirred it all around, let it simmer some more, and here is the reduction I got.
Maybe our addiction to the pursuit of happiness is contributing to brain aging. It's not an umbrella cause, of course. You would never have been able to say that Mom led a hedonistic lifestyle. And Ronald Reagan pursued a lot more things than happiness. But still… The connection between what Dr. Linden was saying and what I've read makes me suspicious.
In David Linden's Compass of Pleasure, he talks about the pleasure area of the brain as being that part that–in response to certain activities or substances–produces dopamine. Dopamine is the "feel good" neurotransmitter in the brain. It is activated when we engage in certain activities or thought processes, but it is also activated when we injest/inject food, alcohol, narcotics.
Some things that produce dopamine are completely healthy. Like a good run, the enjoyment of friends, reading a stimulating book.
Some things are borderline good. Like food. Everybody needs it. The pleasure of good food produces dopamine. But when pleasure is sought after for pleasure's sake, "the brain's dopaminergic circuitry gets blunted. In all cases of producing pleasure in the brain, it takes increasing levels [of a thing] to produce the same level of pleasure" (quoting Dr. L). So with food, you eventually get overweightness if the pleasure of food is pursued beyond the body's need for it. Obesity is contributing to an epidemic of Diabetes, which is strongly linked to brain aging. By indirect means, then, the pursuit of a happy palate can lead to brain aging.
Then there are things that produce dopamine (or cause its production) that are not healthy. Like alcohol, nicotine, cocaine. This falls in with the acetaldehyde hypothesis I wrote about in Does Alzheimer's Take Guts. Alcohol, cocaine, and especially cigarette smoke have–at some point in their metabolic breakdown–the toxic aldehyde acetaldehyde. Very destructive to the brain. Dopamine is produced as the end-process of breaking down harmful aldehydes into harmless acids. It's the brain's "Yahoo!" after saving the day from the bad guys. That "Yahoo!" may be a good thing, but again, in order to get it a second, third, and nth time, you have to increase the attack on the body. [Interestingly, Disulfiram's use to treat alcohol and cocaine addiction works by inhibiting ALDH2 (aldehyde dehydrogenase) which is the enzyme that metabolizes acetaldehyde. It lets the toxin do its full work rather than disabling it by metabolizing it into a harmless acid. So the brain does not get its "yahoo!" And if you get no yahoo, you don't repeat the action.]
The problem with focusing on happiness above all else is that we may end up using the short-cut and more harmful methods of getting that dopamine high.
Dr. Linden's solution? "Try to take your pleasures broadly: exercise, meditate, learn, have moderate consumption of alcohol, moderate consumption of food."
I would add: pursue friendships, do charitable work, tend a garden, read a good book (get more ideas at Changing Aging).
As Captain Kirk once said, "There are a million things you can have and a million things you can't have. Choose the million you can."
See also:
Ethanol and acetaldehyde action on central dopamine systems: mechanisms, modulation, and relationship to stress.
Age-Dependent Neurodegeneration Accompanying Memory Loss in Transgenic Mice Defective in Mitochondrial Aldehyde Dehydrogenase 2 Activity
How much time is enough time? We know we are mortals and we know life is but a breath. In light of eternity, we calculate that 100 years passes as quickly as twenty. Yet, given anything less than 100, and we say we've been "cut off."
My big, strapping brother-in-law lays in the hospital right now, fighting for each new minute after a two-year battle with brain cancer. He is tired, and he is ready to rest. We would prefer the doctors find a cure and make him bounce back, but we want to let him go.
Throughout this whole battle, Ken's mind worked around his brain to bring humor and gratitude to his situation. He firmly believes God's purposes can be worked through the worst tragedies, and it is amazing to hear how his concerns were always for the eternal perspective he could bring to the waiting room, the surgery room, the recovery room.
Ken's life may be cut short in our view, but it has been a life well-lived, and that's more than a lot folks can say. Socrates said that an unexamined life is not worth living; an anonymous person added that an unlived life is not worth examining. I can vouch for Ken that he's had a life worth examining.
April 26, a.m.: Ken had a brain hemorrage last night and is on life support. Awaiting a family gathering to let him go.
April 26, 7 p.m. Goodbye Kenny. From someone who was present at his bedside: " just wanted to write and let you know that Ken's passing was beautiful in the midst of family and hymns and Scripture. The more that Daniel read and Ruth recited the easier his respirations…and soon he just passed on."
We already miss your booming laugh, your exhuberant living, and your unwavering faith. Save us a place at the banquet table, and we'll see you in the morning.
Mom has been pretty much without language for five years now. Three years ago she would occasionally call out "Ken!" (Dad's name) once or twice a week, but other than that, her speech was a non-stop running chatter of "geri geri geri fica fica fica mao mao" and the like. Mostly two syllable experiments in sound. Ah. Also, occasionally–and as far back as 2 1/2 years ago, she would respond to the declaration "I love you" with "too too too too." We wrapped ourselves in that response–a definite sign of comprehension and reciprocity.
Today we don't even get the "too too too." But we do get eye contact and a nod, which is just as good as sign of comprehension.
For all the times I've felt a thrill at the connection still possible with Mom via language, I didn't have a picture of how thrilling it was for her to know that she knew something until one day–about 18 months ago–when I took her to the bathroom. We'd been having a very hard time getting Mom to urinate. She'd hold it for eight, twelve, eighteen hours. We massaged her, waited in the bathroom with her, gave her tons of liquid in hopes of getting her to release the contents of her bladder–to no avail.
One day I sat her down and begged her to go. "Mom, go potty. Let it out. Just let it out, ok?" She leaned over and made a shooing motion with her hand and repeated, "out?" I said, "yes, let it out." She looked at the door, repeated the shooing motion (toward the door) and said "out" with the most excitement I'd seen from her in a long time. She was ecstatic at the small bit of comprehension she possessed at that moment. She knew the word "out!" She knew the word–it's meaning–and it gave her significance.
I suppose it was akin to the feeling Helen Keller had at the comprehension of the word "water." It opened up the world around her; gave her instant availability to connection with other human beings; empowered her to have a "self."
I ache for Mom and her loss of language and all that has gone with it. But thanks to her, I am richer now that I know the power I possess with a vocabulary. Comprehension via language is such a huge gift (sorry to disagree, post-modernists)!
Now, if I can just stall the loss I already feel creeping in…
In continuation of Alzheimer's and Glucose Metabolism: The Niacinamide Experiment Part 1
This post is simply me mulling over things I've read in light of Mom's dementia and my own experience with stress and mental short-circuiting, with the conclusion that in some cases of Alzheimer's, intestinal flora could be greatly to blame. My conclusion also points to the possible way niacinamide could function in correcting one of the malfunctions in the gut-brain axis.
The Gut-Brain Axis
In-depth studies of human intestinal microbes are just now coming into maturity. The Human Microbiome Project is fueled by the increasing belief that the population of bacteria and yeasts that inhabit the human digestive tract is greatly responsible for how the body and mind develop and how they continue to function or malfunction as we tinker with the balance of flora in our gut:
Visionaries are hoping for cures for some forms of obesity and anorexia along with various forms of cancer, asthma, multiple sclerosis, Alzheimer's, lupus, and most of the major psychiatric diseases. In the future, Blaser [of the infectious-disease research lab at New York University] says, pediatricians could help prevent these diseases by infecting babies with a starter kit of friendly bacteria. "Bottom line, humans and our fellow animals have been colonized by microbes for a very long time, going back a billion years. The microbes that we carry have been selected because they are helpful to us. They participate in human physiology. They are a compartment of the body, like the liver or the heart." (1)
When the BP oil spill happened in the Gulf of Mexico, we were all
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In my research on Alzheimer's and glucose metabolism, I ran across a fascinating article about the brain's default system–that part of the brain that is affected in Alzheimer's Disease; that part of the brain that hogs glucose like no other part of the brain.
In The Secret Life of the Brain, Douglas Fox brings together research on the default network beginning with Dr. Sokoloff who, in his attempt to find out why the brain uses so much glucose (20% of the body's supply), discovered that the brain uses as much energy while "at rest" as it does while performing tasks.
Later, a neuroscientist named Marcus Reichle discovered a kind of "brain within the brain" that works its butt off when it's supposedly in "idle mode."
Raichle and Shulman published a paper in 2001 suggesting that they had stumbled onto a previously unrecognised "default mode" – a sort of internal game of solitaire which the brain turns to when unoccupied and sets aside when called on to do something else. This brain activity occurred largely in a cluster of regions arching through the midline of the brain, from front to back, which Raichle and Shulman dubbed the default network (Proceedings of the National Academy of Sciences, vol 98, p 676).
It was found that some parts of this network devoured 30 per cent more calories, gram for gram, than nearly any other area of the brain. Since part of this default system is in constant communication with the hippocampus (which records every day memories), Reichler speculated that its function was to sort, evaluate, and categorize memories in such a way that would allow the brain to use the past as an "inner rehearsal" for considering future actions and choices.
Brilliant. Just when you think daydreaming is a waste of time, it turns out it's crucial for living.
Raichle now believes that the default network is involved, selectively storing and updating memories based on their importance from a personal perspective – whether they're good, threatening, emotionally painful, and so on. To prevent a backlog of unstored memories building up, the network returns to its duties whenever it can.
In support of this idea, Raichle points out that the default network constantly chatters with the hippocampus. It also devours huge amounts of glucose, way out of proportion to the amount of oxygen it uses. Raichle believes that rather than burning this extra glucose for energy it uses it as a raw material for making the amino acids and neurotransmitters it needs to build and maintain synapses, the very stuff of memory. "It's in those connections where most of the cost of running the brain is," says Raichle.
Reichler later attented a lecture by an Alzheimer's specialist and was shown a map of beta amyloid plaques (those clumps found in Alzheimer's autopsies) in the brain. The picture looked exactly like the default network!
Raichle, Greicius and Buckner have since found that the default network's pattern of activity is disrupted in patients with Alzheimer's disease. They have also begun to monitor default network activity in people with mild memory problems to see if they can learn to predict who will go on to develop Alzheimer's. Half of people with memory problems go on to develop the disease, but which half? "Can we use what we've learned to provide insight into who's at risk for Alzheimer's?" says Buckner.
That got me thinking…
Maybe one reason we lose memories is that our lifestyle doesn't allow for much rich idle time like when we would sit on the porch sipping sweet tea on a hot afternoon. So the default network can never do its work of sorting and categorizing memories, and consequently we lose them.
And if this is a problem with the present generation, how much moreso for the upcoming generation. We are consumed with having something to pay attention to all the time. Just look at TV screens these days: not only do you have the main screen, but there's the pop-up ad for the "next show," a caption for what's going on on the screen, and a ticker at the bottom of the screen for what's happening elsewhere.
Maybe part of the solution for AD is the "quiet space" to be incorporated in school, at work, and at home. Hmm, come to think of it, I offered this very solution in a comment to an article in Time Magazine back in 09 (Turn Off, Tune In, Log Out):
I predict that the twitterification of our society is going to lead to an exponential increase in early-onset Alzheimer's. We're increasing the rate of input to our brains and decreasing the time for processing information, and our brains are going to revolt. That, in turn, will lead to the next big industry: de-twitterification rooms where you can sit alone and unconnected, with nothing but a giant aquarium and a beanbag. -Marty
SEE ALSO Language and the Brain's Default Network in Alzheimer's
We already know that a Mediterranean diet helps stave off signs of dementia, but who wants to eat flavorless vegetables all the time?
If you think you have to sacrifice that deeply satisfying taste of butter and meat that you don't typically get in a vegetable-rich diet, you don't know Yum Sauce! This sauce is of Japanese origin and is full of protein, B-complex vitamins (B1, B3, B6, B12), and antioxidants—and best of all, it rounds out the flavor of anything you put it on with a "meatiness" that will satisfy the carnivore in you.
The dish pictured here is a prime example of a Mediterranean diet with a Japanese twist: a bed of baby spinach leaves with sauteed butternut squash, topped with Yum Sauce. Use this sauce on any steamed vegetable, over rice, or even on salad, and you'll be on your way to fighting memory loss!
Yum Sauce
1/2 cup olive oil
1/2 cup water
1/2 cup nutritional yeast
3 packets of lemon or orange-flavored vitamin C
2 Tbsp soy sauce
4 Tbsp almond butter or peanut butter
2 cloves crushed garlic
1/2 cup black beans with juice
1 tsp cumin powder or curry powder
1 tsp white pepper
Throw everything in a blender and puree until smooth. Store in a refrigerator for up to one week.
Here's what happened: I'm not a "from scratch" web coder, so I installed what's called a "theme" for my niece's website and used it as a springboard to create a look that would capture her life and style.
A lot of work goes into designing the look of a website, but it has to pale in comparison to all the work that goes into creating themes, or "platforms" on which creative designs are based. By the time I get my hands on designing a website, all the hard prep work has been done, and I'm presented with a lovely spring board that allows me to jump and flip and fly wherever my creative juices lead.
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Yesterday I finished reading Still Alice. I think the title is meant to be a loaded question. Can I, after losing all memory of others and self, still be considered to be myself? Am I still "me" if I don't have a clue what that me is or was?
The fictional book answers the question affirmatively.
I found myself examining my perceptions of Mom–who obviously no longer knows herself–and thinking the conclusion was absolutely true. I still recognize Mom in this shell of a person. She still has the same mannerisms, exudes the same kind affection, displays the same funny reactions. She's still Mom down to the core.
But not so much with Dad–a victim of Parkinson's. It seems I recognize him less and less. But then, I suppose I'm holding a higher standard of "self" to Dad, giving that I'm assuming he's more "there" than mom. If I were to strip him down to mannerisms alone, I would probably find him to be his old self too. It's a tricky question.
At the very end of the novel, Alice has a moment of lucidy and says, "I miss myself."
That statement struck me to the core. You know why? Because I miss being me too! There is this incredible longing inside me to be "more" or "better" or "fuller" or something. I fall way short of the me I want to be, and I long for (or miss) that. Yet I still want to be treated as though I were fully "me" even though I don't meet my own standard for myself.
Why not, then, treat the Alzheimer's victim as though they were fully themselves, regardless of how short they fall from the perfect version of that self?
Ultimately, our longing is for acceptance, love, safety. Let's just make a pact to offer it unconditionally to each other regardless of where we are on this journey toward the perfect self.
Alzheimer's and the Ego: the Power of No
I saw an old friend yesterday and we caught each other up on our families. I told him I recently lost my brother-in-law to brain cancer. He said he was about to lose his sister to the same. Then he shared how his sister—who has a month or two left to live and is tired as can be—blurted out a couple days ago that "There are just so many fun things left to do." No self-pity; no giving up despite the shortness of time. Her mind is winning over her dying brain.
I am deeply humbled by this woman's attitude. I want to think like her—to take what's left in the glass and drink it! Yet here I am with probably years left to live, claiming to be getting the upper hand on this Alzheimer's caregiving business, but feeling devoid of creative ideas for living, for laughing, for loving.
I need help making a list. I have to have a bunch of small stuff, because the big stuff like going to a play or out to dinner or hang gliding don't work with both parents. I just want some ideas for bringing laughter into our home.
To start, here are some little things that make Mom laugh:
Dancing for her with a feather boa.
Episodes of "I Love Lucy."
Singing raucous songs loudly.
Pretending to eat her up.
Laughing babies (like this youtube one):
Here are some things that make Dad laugh:
Pretending to eat him up.
Episodes of The Colbert Report.
Mom when she's in a funny mood.
And here are some new things I'm going to try:
Wear a fake mustache to the dinner table.
Spray whipped cream on Dad's nose.
Put a fake snake or tarantula in the bathroom before Dad goes in.
Find a DVD of Victor Borge (like this youtube):
I'd love to hear your ideas, and I'll leave you with this fun project: make a muppet like the one in the introductory picture above to add some fun to your Alzheimer's caregiving.
Wait, here's another idea: make these funky glasses. They crack everybody up!
The U.K. recently decided that Aricept and other acetylcholinesterase inhibitor drugs can be prescribed for mild Alzheimer's cases (in addition to moderate cases. See article U.K. Reverses Stance On Alzheimer's Drugs NICE is now recommending that three drugs known as acetylcholinesterase inhibitors—Aricept from Pfizer Inc. and Eisai Co.; Reminyl from Shire PLC; and Exelon from Novartis AG—be considered for use in patients with "mild" forms of Alzheimer's, in addition to the patients with "moderate" forms of Alzheimer's for whom NICE previously endorsed the drugs.). The more obvious reason is that these drugs should be getting cheaper once their patents expire, and therefore easier on the state's prescription coverage budget. The less obvious reason is the relative ignorance Brits have regarding the sport of baseball.
I'll explain:
First, you have to know how neurons and neurotransmitters work. Here is a short animation that shows how neurotransmitters work in the brain:
The cycle is a fantastically efficient one. Neurotransmitters are shocked into action, released into the synapse where they interact with receptors on the other side of the synapse, then swept up to make room for the next wave of neurotransmitters.
In Alzheimer's, the favorite neurotransmitter tagetted by drug companies is acetylcholine because it is crucial for the formation of new memories. In the Alzheimer's brain, there is an increasing shortage of acetylcholine, making it harder and harder for the brain to form new memories. The enzyme that recycles acetylcholine is acetylcholinesterase. What Aricept (an acetycholinesterase inhibitor) does is inhibit this recycling process, so the neurotransmitters hang around longer in the synapse and interact more often with memory-forming receptors.
Here is a video of a different neurotransmitter (serotonin) and its recycling inhibitor. It's a good picture of the process that takes place with acetylcholine and acetycholinesterase inhibitors:
All of this is easier for Americans to grasp, because it can be compared to baseball: in baseball, players are stored in the dugout, called into action on the field, then recycled back into the dugout when their action is no longer called for.
Suppose that a team were to lose all but four of its players. Someone would have to block the dugout so the players wouldn't sit back on the bench but rather take up the bat once more.
The players are the acetylcholine, the rule that sends them back into the dugout is the acetycholinesterase, and the person blocking the dugout when there is a shortage of players is the acetylcholinesterase inhibitor.
This also, by the way, illustrates why Aricept et al eventually fail: the four players get tired of playing the whole game all season long and quit.
Someone must have finally explained baseball to the Brits.
Today a nice physical therapist came to assess a treatment program for Dad—to help him regain his balance and mobility and in so doing help him milk the summer ahead of us.
A couple hours later, while sitting at the table Dad asked me in an unusually clear voice, "What's the agenda?"
I looked up from the computer, slid my glasses down, and asked back, "Agenda for your physical therapy?"
"Agenda for life?" (I thought I'd go for the gusto).
"Yes." He smiled.
"Ah. Well. The agenda for life is to live more fully. You are going to get back to being more fully you. We are going to visit the local museum, go see the natural wonders around us, go to the big city to check out the OMSI exhibit."
He smiled more broadly. We're on the right track.
Shoot, this Parkinson's is going to be a nuisance, but we are going to live one shaky bite, one shuffling step, one tough lesson, one adventurous ride, one grateful day at a time.
One thing Parkinson's can't take away from a man is all he has passed on in his lifetime. Here is Dad, rock-hounding Parkinson's style. The fact that he can't stand up on his own or kneel and claw through the dirt to get to the jasper or petrified wood doesn't detract from the fact that he instilled the love of nature and science in his children. It's in our blood now to visit all the national parks we can and to dig for fossils wherever there be beds.
He's taught his children so many good things, and Parkinson's can't take that away from him.
Here's a short section of a CNN interview of Michael J Fox done by Sanjay Gupta—about living with Parkinson's:
"Liberating" is what Michael calls his Parkinson's! A chance to do something significant with his life! The turning point? The diagnosis. The act of giving a name to his symptoms allowed him to take back control of his life. Wow!
I cried throughout, of course, because Dad's Parkinson's was nothing liberating. But the reason it was such a cage, I think, is that it went undiagnosed until the very end. His shaking was written off as "familial tremors" (like his father and brothers who likewise had hand tremors without Parkinson's) for twenty years, so all his other symptoms—an expressionless face, shuffling gait, forward tilt, drooling, even dementia—weren't blamed on a disease: Dad had to take the blame himself.
I'm sorry, Daddy. How freeing it would have been to know your body was beyond your control. I think it would have helped your mind to gain control over your brain.
I hope this will convince anyone out there who suspects they may have Parkinson's to get a thorough neurological examination. Take control of your disease and don't let it eat up the rest of your life.
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Home > News > Wave-powered 'ducks' could purify seawater
November 8th, 2006
Wave-powered 'ducks' could purify seawater
Ocean waves could provide an energy-efficient way to desalinate seawater, say UK researchers. While conventional purification plants have high energy demands, the rocking motion of floating buoys could be used to drive a pump system for desalination.
These plants drive water through membranes that filter out salt, but their efficiency is limited because they can become clogged (see Desalination may be best hope to slake world's thirst). Nidal and colleagues are researching ways to solve this problem using nanotechnology. "Already the cost of fresh water is down to around 40 US cents per cubic metre," he says. "The next-generation membranes should make that even lower."
New Scientist
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The transmission speed of 40 Gbit/s is the highest commercially-available rate that uses the simple light on/off keying or serial transmission scheme.
What does TS stand for?
TS stands for Transmission Scheme
This definition appears frequently
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Other Resources:
We have 114 other meanings of TS in our Acronym Attic
- Abbreviation Database Surfer
- « Previous
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- Transaction Server
- Transfer Start (memory controllers)
- Transfer Station (waste, shipping, mining)
- Transfer System (various companies)
- Transient State (of a reaction or system)
- Transit Storage
- Transit Switch
- Transition Season
- Transitional Strategy
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Samples in periodicals archive:
com/prnh/20130129/SF49903LOGO) The transmission speed of 40 Gbit/s is the highest commercially-available rate that uses the simple light on/off keying or serial transmission scheme.
95 Hardcover TK5103 Portuguese telecommunication scholars describe transmission schemes suitable for future broadband wireless systems, and propose and study several advances in transmission techniques and receiver design to support emergent wireless needs for fourth-generation wireless communications.
The major projects acquired in Pakistan during the year include West Bank Bypass Project Muzaffarabad, Quick Impact Projects FATA, Prime ministers Southern Punjab Water Supply and Sewerage Schemes Multan, Transmission Scheme for dispersal of water from Neelum-Jhelum Hydropower Project, 500 kV transmission lines 3rd circuit Jamshoro-Moro-Dadu-Rahim Yar Khan and Moro Substation projects.
Other topics explored include a high spectrum efficiency transmission scheme, the application of web mining in distance education platforms, a financial derivatives model using GPUs, an optimized anonymous attestation protocol from bilinear pairing, and implementation of QoS in mobile video surveillance.
In comparison, transmission schemes such as gigabit over copper require compression codices, multiplexed transmission over multiple twisted pairs and higher-frequency cabling like Category 5e or Category 6.
In this paper, we assess the stability of BEB and analyze its performance using a model that closely resembles practical network transmission schemes and therefore is useful for system planning and analysis.
More than 30 transmission schemes, plus several thousands of others designed to improve transmissions, will benefit from the cash injection.


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This Could Be One of the Most Underestimated Employee BenefitsJuly 20, 2015
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Kukla's Korner Hockey
Jere Lehtinen Retires
by Paul on 12/08/10 at 07:48 PM ET
Comments (2)
from Stars.com,
Former Dallas Stars player Jere Lehtinen officially announced his retirement today as a player in the National Hockey League.
Statement from Jere Lehtinen:
"First of all, I wanted to thank Joe Nieuwendyk and the Stars organization for giving me some time to come to this decision. They respected the fact that I wanted to be 100 percent sure prior to making this announcement, and I appreciated that.
It's a tough decision due to the fact that you play hockey your entire life and then must decide to stop playing. However, I choose to focus on all the great times I had playing over the past 15 seasons, understanding that I am very fortunate to have played all those years with one organization. The memories I have playing in Dallas will never be forgotten and I will always be proud of the fact that I finished my career where I started it.
There are so many people that have positively influenced my career, including the entire Dallas Stars organization, the coaches, the players, the trainers, the fans and most importantly, my family. To all of those people I want to say thank you. Everybody that touched my career in some facet, whether small or large, had an impact on me and I will always remember that. Thank you."
Filed in: NHL Teams, Dallas Stars, | KK Hockey | Permalink
Tags: jere+lehtinen
Farewell, fine Finn. You will always be one of the guys that every coach wants.
Posted by Mojo Tooth on 12/09/10 at 02:58 AM ET
Hardworking classy guy like most Finns. Happy retirement to Jere.
Posted by Moq from Denmark on 12/09/10 at 02:45 PM ET
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