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The Odd Even rule has this great feature where a Delhi elite cannot carpool or take public transport without sharing 5 pictures on Twitter.
KYA TUMNE KABHI KISI SE PYAAR KIYA? *crowd goes silent and gets depressed on being reminded of the heartbreak*...
1 Jan 2016: I am going to exercise. 7 Jan 2016: I am going to exercise my right to eat and drink and sleep.
Bhakto ke reaction: 1. When Congress wali Sarkar engages in talks with Pak 2. When BJP wali Sarkar engages with Pak...
बूढा दिसम्बर जवां जनवरी के कदमों मे बिछ गय...
Female subordination in print advertisements...
Khayam Chowk Srinagar – The Street food Gali...
A world of my dreams...
Shweta Taneja is a tantrist masquerading as an author, graphic novelist and journalist. She is known to hex people who annoy her, or order a hit on them through underworld hitmen. Just kidding. She's just a very prolific writer, churning out books, blogs, graphic novels and articles at the speed of light. We suspect that she gets some supernatural help considering the speed and variety in her writing. We probed a little into Shweta Taneja's life with our questions, and this is what we came out with.
Someone who is attracted by faces! He absolutely loves to capture faces and emotions. Most of the pictures on his blog would leave you spellbound! Joshi Daniel, the winner of the Best Blog in the Photo & Video Category interviewed at your Adda!
I believe in cooking according to moods and seasons
Is Conformism the Key to Happiness?
Dare to dream…..
How Far Have You Come?
The parents were right. We screwed up.
While growing up, everyone has ideas and dreams about their first job, their first foray into the professional world. Internships, which were optional a few years back, have now become the norm for youngsters to get the hang of their chosen profession. Your first internship is like being born all over again, as you leave the comfortable world of your college and are thrust into the bright, shiny world of professional adults. Your first internship is a memorable experience, and we're calling all bloggers to relive your internship memories with the #MyInternTheory activity in association with Intern Theory.
Every relationship is different, but there are some essentials that form the foundation for every single one of them. They are love, trust, commitment and promises. Every couple makes some promises to each other, and we're not talking just about wedding vows. These promises are unique to every couple, and that's the beauty of them! So ladies, this is your chance to tell your partner/ future knight in shining armour the kasams you'd like him to make! Participate in the SetWet #SadaSexy activity and get assured vouchers and a chance to win vouchers worth Rs. 1000 each!
We call nature our 'Mother', but do you really think we're treating her like in a way that a mother deserves? Today, we are behaving with Mother Nature with utmost disrespect - using up all her resources, killing off forests, rivers and entire ecosystems in our greed for more money and more products. We keep forgetting that we have only one Earth, and this is the planet that is going to sustain our future generations. The good news is that the power is still in our hands, more specifically in the hands of future generations. Blog about 'How to teach our kids to press Ctrl+S for nature?' for the Shortcut Safaari weekend activity and win movie tickets!
Post Ideas: At times you will just run out of ideas for post not sure what to do. use google and apps like Evernote to note down all that ticks in your mind. Something will surely turn into a new post.
Search engines don't spare any blogger. E-commerce bloggers must keep in mind the search engines in mind while writing blog posts. SEO friendly writing improves the search of your blog content.
E-commerce bloggers must carefully write keeping their audience in mind. Everything you post on your blog will speak for your product or service. Your interaction with bloggers in comments and otherwise will give you a direction.
How many times have you seen yourself in a mirror and wished to see yourself through somebody else's eyes? It's natural to be curious about how we are perceived by people and which of our traits stand out. Are you well versed enough with your traits as to write a WOW post about them?
Grandparents are the charm of almost all families. The transformation from parents to grown children to grandparents of little ones is almost magical. They fill the family with a sense of wisdom and emotional security. A simple talk with them can enrich our lives with cool life lessons which they have gleaned over the years. Let's give an ode to grandparents with this week's WOW prompt, shall we?
There are some things we find mysterious, and some which are spooky. What would you do if a place ignited both curiosity and fear in you? Abandoned places are scary, blank canvasses which your brain can paint with the best or the worst images. Now close your eyes and imagine 'An Abandoned Warehouse'.
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text: December 18. 2015 – April 16. 2016 – 200 original objects from the Lucas Museum of Narrative Art of Chicago create a character-driven adventure into the Star Wars universe. Incorporating and fictional elements help visitors to create their own personal and original Star Wars identity during the exhibition. (1, Austrian Museum of Applied Arts / […]weiterlesen »

subset: commoncrawl


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Gift Premium Subscription To Harry482
Join Date:01-09-2013
Last Activity:05-04-2016 3:27 PM
19 Likes on 10 Posts
- Male
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Posted in thread: all 3 grainfather beers cloudy? on 04-02-2016 at 11:42 PM
A little cold conditioning will clear it right up. If not, then you aren't getting full
conversion and it's time to check your mash ph.
Posted in thread: So who's brewing this weekend? on 04-02-2016 at 11:32 PM
Brewing 12 gallons of a hoppy red ale tomorrow. Upping my batch sizes to make for time for yard
work - wamp, wamp.
Posted in thread: What's Your Lawnmower Homebrew? on 03-17-2016 at 04:36 PM
Maris Otter and east kent golding smash. Mash 10lb mo at 152. 1oz 60 min and 1 oz 20 min. So
easy and so good!
Posted in thread: Want to see your pictures on HBT's Instagram? on 02-23-2016 at 10:51 PM
Brewed a small batch of bitter last weekend. First brew in my brewing area of the new
[email protected]
Posted in thread: Baltimore MD???? on 07-16-2015 at 01:44 AM
I live in Baltimore. I can vouch that Brewers Art is hands down the best brewery in Baltimore!
Check out their website.
Posted in thread: Blichmann Washer Sizes on 07-12-2015 at 06:28 PM
Your best bet would be to just contact Blichmann and get it from them.
Posted in thread: Florida to NY - Good breweries to hit on 05-20-2015 at 11:03 AM
Brewers Art in Baltimore is the best in Maryland. Assuming the city isn't on fire at that time.
Posted in thread: Brew Day Horror Stories on 05-18-2015 at 11:51 PM
I've tried brewing with a buddy before and it always gets me too distracted. I will not so much
as talk to anyone until the chiller goes in! I'm a social person, but friends and brew days
don't mix fo...
Posted in thread: Eye-Catching Safety Tips on 05-10-2015 at 01:52 PM
Don't lift large pots full of hot wort. A pump can be considered a safety item. Sent from my
iPad using Home Brew
Posted in thread: Brewers Art Resurrection on 05-08-2015 at 10:13 PM
Hopefully I'm not posting this in the wrong place...... I'm looking for a clone recipe of
Brewers Art's Resurrection Belgian dubbel brewed in Baltimore. It's an amazing beer and I would
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The Temuka Community Board is opposed to an "at large" elected Timaru District Council.
At last night's board meeting members were clear that Temuka has its own community of interest, and this was best protected through a ward system.
The Timaru District Council voted last week to abandon the ward system in favour of councillors being elected across the whole district, while retaining the three community boards of Temuka, Pleasant Point and Geraldine.
At present these three districts have one councillor each, and Timaru seven.
Board member Noeline Clarke moved that the council reconsider its proposed changes to the voting system.
"Temuka Community Board opposes the council's decision for election at large based on the grounds that Temuka is a geographically identifiable community of interest best served by separate representation.
"I feel our community would be severely disadvantaged if we didn't have local people representing us."
The board agreed that the best combination representing Temuka was to have five elected community board members and two councillors.
Chairman Pat Mulvey said the threat of local representation being taken away from the community was concerning a lot of people.
"The people that have come to me about it have got steam coming from their ears. They are really upset that council appears to be taking away the community of interest's voice, and that's one of the pillars of local government."
- The Timaru Herald
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One person killed, another seriously injured in helicopter crash
District health board complaints increase
Timaru man wins million dollar Queensland home in lottery
Teaching youth the art of graffiti
Attempted Waimate ute attacker Daniel Vickers convicted
World record-holding Geraldine mosaic heads to England
Boosted South Island Masters Games to boost Timaru economy
South Canterbury charities compete for tightening community dollar
Mystery illness blamed as man leaves his rural home
Shortage of dementia beds prompts concern
Potential purpose-built helipad for Timaru Hospital
Opihi River cyanobacteria warning lifted
New measures to address speeding on Derwent St
One person killed, another seriously injured in helicopter crash
Teaching youth the art of graffiti
Timaru man wins million dollar Queensland home in lottery
World record-holding Geraldine mosaic heads to England
Shortage of dementia beds prompts concern
Editorial: Have church, willing to negotiate
Crash victim's body heading home to Jordan
Rising basketball star Bianca Small aims to impress in the US
Residents gradually warming up to idea of home-heating appraisals
More jobs if wool scour firms merge
Charging battery bursts into flames
White crosses mark those who fell in WWI
Dream for Timaru Titans league team fails to get off the ground
Art feeds the soul at Bread of Life
One person killed, another seriously injured in helicopter crash
Timaru man wins million dollar Queensland home in lottery
Double setback for Hayden Paddon as German driver leads Rally Whangarei
Mystery illness blamed as man leaves his rural home
Teaching youth the art of graffiti
Farmers adopt gumboots approach to reduce their effect on local environment
Attempted South Canterbury vehicle attack trial begins
Front expected to bring an end to fine weather just in time for the weekend
Celtic remain unbeaten in romp against Geraldine


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New Music Works 2015 -16 season
music and the spirit of imagination have no boundaries
New Music Works opens its 37th season with its sixth or seventh installment of NIGHT OF THE LIVING COMPOSERS, a concert that celebrates the musical art of eight composers living in Santa Cruz and nearby counties. Following this tribute to indigenous modernism, Concerts Two and Three expand with global confluences that encompass new music form the Middle East, Africa, and Europe.
2-6pm, Sunday, June 5
"The Garden"
2701 Monterey Ave., Soquel
The FULL AZA!! The phenomenal AZA sextet, led by co-founders Fattah Abbou and Mohamed Aoualou, bring the best of Moroccan Berber music to Santa Cruz; The Ariose Singers perform music by Saad Haddad and other works; nMw Ensemble perform chestnuts of the 2015-16 season.
Stay tuned for updates!
Join this event on Facebook to invite friends & support its visibility
Tickets available on Brown Paper Tickets.
AZA unites traditional Tamazight (Berber) music, indigenous to the Atlas Mountains of Morocco, with the global influences of its diverse members. Evocative of Saharan-African blues, yet with an original style that truly defies categorization, AZA's stirring performances feature deep, danceable rhythms, intricate string melodies, and soaring, soulful vocals. Visually dynamic and engaging performers, AZA has been inspiring international audiences for nearly seven years.
Founding members Fattah Abbou and Mohamed Aoualou are Berbers native to the High Atlas mountain region of Morocco, where they played and studied music for over twenty-five years, and are recognized as master musicians. They formed the sextet AZA in Santa Cruz, California, after moving to the United States eight years ago. The unique exchange between the High Atlas and Californian musicians has proved potent; AZA has produced two albums of original compositions, and performed at music festivals, clubs, and universities around the United States and abroad. In 2006, AZA was invited on its first of three annual summer tours to Morocco, to perform at music festivals throughout the country.
AZA's endeavors are not limited to music. The Berbers, or "Imazighen" (preferred term), are the indigenous people of North Africa whose recorded history dates back to 3300 years ago. Fattah and Mohamed have always been part of the Amazigh movement and struggle to revive a culture that has been marginalized for centuries. Through music and cultural events, AZA continues to inspire awareness in people of all ages about the Amazigh culture, that it may be recognized and appreciated among the indigenous cultures of the world.


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Home > News > Nokia CTO mission: Reinvent the company
February 11th, 2008
Nokia CTO mission: Reinvent the company
CW: Could that mean the end of our hundred-year dependency on batteries?
Iannucci: Maybe. I think it's likely that there will be energy storage in some form in the device and the nature of batteries is probably going to change. The nanoscientists and what they are doing at the University of Cambridge points to that direction. We're looking at technologies that could only be made on nanoscale to create energy storage devices that are sort of a hybrid between a battery and a capacitor. A supercapacitor probably is the best description for that. And maybe that wireless power becomes a long-term direction when you'll have some capabilities for energy storage. When you're outside the range of your local wireless power transmitter you can still operate, or you're in range, recharge it.
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Personal cooling units on the horizon April 29th, 2016
Exploring phosphorene, a promising new material April 29th, 2016
Arrowhead Pharmaceuticals Files for Regulatory Clearance to Begin Phase 1/2 Study of ARC-521 April 28th, 2016
The Translational Research Center at the University Hospital of Erlangen in Germany uses the ZetaView from Particle Metrix to quantify extracellular vesicles such as exosomes April 28th, 2016
Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers
Personal cooling units on the horizon April 29th, 2016
Exploring phosphorene, a promising new material April 29th, 2016
Researchers create a first frequency comb of time-bin entangled qubits: Discovery is a significant step toward multi-channel quantum communication and higher capacity quantum computers April 28th, 2016
Hybrid nanoantennas -- next-generation platform for ultradense data recording April 28th, 2016
Battery Technology/Capacitors/Generators/Piezoelectrics/Thermoelectrics/Energy storage
New spin Seebeck thermoelectric device with higher conversion efficiency created April 26th, 2016
Highlights from the Graphene Flagship April 22nd, 2016
Adding some salt to the recipe for energy storage materials: Researchers use common table salt as growth template April 22nd, 2016
Cleaning up hybrid battery electrodes improves capacity and lifespan: New way of building supercapacitor-battery electrodes eliminates interference from inactive components April 22nd, 2016
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Republican front-runner Donald Trump's last remaining challenger suspended his campaign after finishing third in Indiana's primary, U.S. news outlets report.18:57 04.05.16 | 0 comments
40 catholic Bishops instruct their to refuse to rent or sell to Jews. Hmmmm. As to Netanyahu --he is joking--if that stranger happens to live in the future Greater Israel--he is not likely to be --loved.


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Patriots receiver Deion Branch, who had a 61-yard touchdown in Saturday night's 45-10 victory over the Broncos, said following the game that the past two weeks of practice paid off as the Pats limited mistakes in a dominant showing.
"We knew what was at stake. We wanted to go out there and take care of business," Branch said. "Not saying that we didn't want to do it last year … but the biggest thing was going out there an trying to play mistake-free football. We almost did that."
Branch also said the team, which has lost three straight playoff games, was focused on not going one-and-done for a third straight postseason. The Pats were eliminated by the Ravens and Jets in the past two seasons.
Said Branch: "I think the vibe was in the building all week. … Our playoffs started last week in practice, so we had two weeks of preparation to get prepared to play this one game, and I think we did a...
FOXBORO -- Tom Brady threw an NFL-record five first-half touchdowns, including three to Rob Gronkowski, to lead the Patriots to a 45-10 romp in the AFC divisional playoffs Saturday night at a frigid Gillette Stadium. The win sends the Patriots to their eighth AFC championship appearance, and was their first playoff win since capturing the 2007 AFC championship on their way to Super Bowl XLII, snapping a string of three straight playoff losses.
The temperature at kickoff was 24 with a wind chill of 12 above. But Brady warmed to the task, throwing TD passes of 10, 12 and 19 yards to Gronkowski, the last one coming with just five seconds left before halftime to put the Patriots up, 35-7, at the half. Brady finished 26-of-34 for a franchise playoff record 363 yards. Meanwhile, the Patriots defense swarmed Tim Tebow all night, making it miserable for the triple-option quarterback. The Patriots held Tebow to 9-of-26 for 136 yards and sacked him five...
It wasn't like anyone expected the Celtics to fly out of Indiana on the second night of a back-to-back with a victory, if you needed any more evidence that they have a long way to go, it was provided in a 97-83 loss. It's also worth noting that the Pacers were also on the second end of a back-to-back.
The starters got off to a much better offensive start, but it was the second unit that couldn't keep the momentum going and they had nothing left in the second half. Defensively, they let the Pacers control the paint and they couldn't keep them off the free throw line.
The one bright spot was Kevin Garnett who had a bounceback game with 21 points and six rebounds and was much more aggressive offensively. Paul Pierce also scored 21 points by getting to the free throw line and knocking down a couple of 3-pointers, but he also had six turnovers.
The Celtics have now lost four straight games and are 4-7. They play Kendrick Perkins and the Thunder...
A Jay Harrison shot off Dennis Seidenberg found its way past Tim Thomas with 90 seconds remaining in the third period Saturday night, giving the Hurricanes their first lead of the night and the only one that mattered, as they handed the Bruins a 4-2 loss at RBC Center.
Harrison's goal, his seventh this season, broke a 2-2 tie after the Hurricanes erased two Bruins' leads. Patrice Bergeron gave the B's a 1-0 lead in the second period with his 12th goal of the season, but Patrick Dwyer tied it minutes later. Milan Lucic put the B's back on top in the third, but three straight goals from Justin Faulk, Harrison and Eric Staal (an empty-netter), gave the Hurricanes the victory.
While the Bruins have put together a dominant season, the Hurricanes, who began the night 14th in the Eastern Conference, have been an Achilles' heel for them. Saturday's loss dropped the Bruins to 0-3-0 against Carolina this season.
For more on the Bruins,...
Alex Smith found Vernon Davis for a 14-yard TD with 14 seconds left to give the 49ers a 36-32 win over the Saints in a wild NFC Divisional Round contest Candlestick Park that featured four lead changes in the final 4:11 of the fourth quarter.
Smith finished with 299 yards passing and three TD tosses. Davis caught seven passes for 180 yards and two TDs.
Drew Brees connected with Jimmy Graham on a 66-yard TD with 1:48 left in the fourth quarter to give the Saints a 30-29 (Darren Sproles hauled in a Brees pass for a two-point conversion).
The 49ers capitalized on two New Orleans early turnovers (including a fumble at the San Francisco 2 from Pierre Thomas), jumping out to a second-quarter 17-0 lead as Smith connected on TD passes to Davis and Michael Crabtree and David Akers converted a 25-yard field goal. The Saints rallied to cut the halftime lead to 17-14 as Drew Brees tossed TD passes to Jimmy Graham and Marques Colston...
Giardi and Price discuss the mega deal that CB Josh Norman signed with Washington and if he is worth it. They also relate it to the Pats and Malcolm Butler. Does the Norman deal mean that Butler is about to cash in and will the Pats go along for the ride? This leads to a discussion on other players the Patriots need to extend very soon.
Danny Vitale, the SuperBack - a fullback/TE hybrid type - joins GIardi and Price on NFL Sunday to discuss the process of entering the NFL Draft, the combine and interviewing with various NFL teams including your New England Patriots.
With the NFL draft only a few days away, Mike and Chris preview how things are shaping for the Pats and the rest of the league. It will be a strange this year since they don't have a first round pick - how will Belichick and company approach this dilemma? Also, would the Pats contemplate the idea of trading Jimmy G?
Kevin O'Connor of CelticsBlog joined Sam Packard and Jared Weiss for a breakdown of what went wrong in the Celtics series against the Hawks. they then played Celtics free agent tinder and looked ahead to the big moves in store for the offseason.
It wouldn't be a Celtics v Hawks Game 6 preview/Game 5 breakdown without ESPN's Celtics Whisperer Chris Forsberg joining Sam Packard and Jared Weiss for some WEEI Studio magic. They discuss the Hawks' transition dominance on their mega runs and the bizarre night for Isaiah Thomas. Of course they also answered your #WEEICeltics Tweet Bag questions!
The boys recap Marcus Smart and Paul Millsap's incredible battle in the Celtics' Game 4 win over the Atlanta Hawks with ESPN's Chris Forsberg. Jared Weiss and Sam Packard discussed Jared Sullinger's struggles and the reemergence of Machine Bun Kelly. They discuss inside media stuff like when to applaud for honorees and Chris' devotion to southern unsweetened tea. Of course they answered your #WEEICeltics Tweet Bag questions too.
Red Sox third base/infield coach Brian Butterfield joined Rob Bradford to get his take on Hanley Ramirez, Travis Shaw and Pablo Sandoval. Butterfield, an avid Patriots fan, also predicts who the Pats might take in the second round, while giving a very pointed message to NFL commissioner Roger Goodell.
Joe and Tim talk with Red Sox second baseman Dustin Pedroia after he had a two home run game, one of which was a grand slam that propelled the Red Sox to a 9-4 win over the Atlanta Braves
We sit down with the Skipper of the Sox, manager John Farrell joins Dale, Holley and Thornton for his weekly visit.
DJ and Pete continue to assess the season that was for the Bruins and look toward the future for the franchise and how they can improve.
DJ and Pete are together for the final Sunday Skate of the season. They get into their overall thoughts on the season, the Bruins keeping Claude Julien on as head coach and the end-of-season press conferences last week. They discuss the rebuild process, what the Bruins need and how they can obtain it. Plenty of callers have their own theories and opinions on all of these topics as well.
Butch is joined by two-thirds of the Sunday Skate show in DJ and Pete. The guys discuss the problems with Bruins including leadership and grit, who should stay and who should go and if Claude is to blame.
Lucy calls in to talk about her podcast and the "More Than Mean" tweets. The guys are now big fans.
All the latest stories brought to you by Kirk Minihane.
Dino, Gerry and Kirk discuss what the Patriots will be looking for on the second day of the draft.
After forfeiting their 1st round pick, the Pats get to join the party and draft some new young talent. The guys look at who the team might select over the weekend.
Kirk took more shots at Glenn, Lou and Christian, so the midday show guys respond.
Glenn, Lou and Christian talk about how much money Laremy Tunsil lost when his Twitter, Instagram, and iPhone photos were hacked. The gang also addresses some ESPN on ESPN crime as Dan LeBetard took a few shots at Todd McShay.
We continue to talk NFL Draft, Brady's new lawyer, the Celtics playoff bouncing, Roger Goodell's award tour and more... its all on the table on a freestyle friday.
We discuss the hiring of a top notch litigator by Brady and the NFLPA, and how it might have been sparked by Roger Goodell's neverending award tour where he continues to spew lies and half-truths to the public.
We discuss the Celts exit from the playoffs, the steps they took this season to be better, and what steps need to be taken to keep getting better in the future.
It's all about the music – the crew touches on Prince, and the greatest bands of all time
Mikey, Christian Arcand, and Chris Villani talk about the Sox horrific loss today, and MJ takes over the text line
Mikey, Christian Arcand, and Chris Villani talk about the Sox horrific loss today, plus they're joined by Cassie, the Textress
Kevin O'Connor of CelticsBlog joined Sam Packard and Jared Weiss for a breakdown of what went wrong in the Celtics series against the Hawks. they then played Celtics free agent tinder and looked ahead to the big moves in store for the offseason.
Red Sox third base/infield coach Brian Butterfield joined Rob Bradford to get his take on Hanley Ramirez, Travis Shaw and Pablo Sandoval. Butterfield, an avid Patriots fan, also predicts who the Pats might take in the second round, while giving a very pointed message to NFL commissioner Roger Goodell.
The Revolution continue to sputter but all of a sudden Ben & Russ have switched their opinions on how they look. They also address the upcoming Copa America Centenario.
We check in for the national perspective on Tom Brady's reinstated suspension from MMQB/SI's Peter KingMore from this show
Is the fire out? The passion Patriots fans once held for this topic seems to have fizzled. We explore what the Patriots do from here, especially the first four games of the season.More from this show
The guys look at what's next for Tom Brady.More from this show
In the latest edition of the It Is What It Is podcast, Chris Price talks with ESPN's Field Yates about the Patriots and what they'll do at quarterback in the wake of the latest Deflategate ruling. Chris and Field also discuss how New England is going to approach this year's draft, as well as how the Pats stack up against the rest of the AFC East at this point of the offseason.More from this show
The guys look at the reaction to the Mean Tweets PSA.More from this show


text:
Anyone Can Be Saved
This is for the soul you have given up on. The issue is not how far gone they are. The issue is how far Jesus has gone. Jesus left heaven. He came all...Read More →
This is for the soul you have given up on. The issue is not how far gone they are. The issue is how far Jesus has gone. Jesus left heaven. He came all...Read More →
Two roads diverged in a wood, and I- I took the one less traveled by, And that has made all the difference. -"The Road Not Taken" by Robert Frost I remember when...Read More →
If you listened to our president in his 2016 State of the Union address, you might come to the conclusion you are living in a great nation. "The United States of America, right...Read More →
"You can sit in the middle," Elias told me as the event got started. Here I was sitting on the outdoor stage at Golden West Community College student center. Two Mormons were on...Read More →
Are you equipped to evangelize? If someone came up to you and asked how to be saved would you know what to say to them? Could...Read More →
"Will you not revive us again, that your people may rejoice in you? Show us your steadfast love, O Lord, and grant us your salvation." ~Psalm 85:6-7 I want to share with you...Read More →
I've got good news and I've got to share it with you! This week God opened the door to talk with four people who professed repentance and faith in the gospel! One salvation...Read More →
My heart was about to burst out of my chest with excitement. People were streaming into the first service in our new building. The seats were filling up. And for the first time...Read More →
Jesus saw people as souls. That's what Matthew 9 tells us: 36 When he saw the crowds, he had compassion for them, because they were harassed and helpess, like sheep without a shepherd....Read More →
On Sunday we made an exciting announcement at Compass HB: God has given us a building. Starting in the new year, we will be leasing a 24/7 facility. Lord willing, our first service...Read More →


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This year will feature a four-fold deeper dive into checkpoint-restore technology, thanks to participation by people from a number of additional related projects! These are the OpenMPI message-passing library, Berkeley Lab Checkpoint/Restart (BLCR), and Distributed MultiThreaded CheckPointing (DMTCP) (not to be confused with TCP/IP), in addition to the Checkpoint/Restore in Userspace group that has participated in prior years.
Posted today to the GPUOpen blog was a guide on setting up the Radeon Open Compute Platform (ROCm) support. The RoCm 1.0 platform consists of the ROCK kernel driver, ROCR runtime, ROCT Thunk Interface, HCC compiler, LLVM-AMDGPU-Assembler-Extra, and LLVM/Clang. AMD/RTG offers the Radeon Open Compute Platform packages for Ubuntu/Debian systems as well as Fedora/RedHat distributions.
Matt Fleming at Intel sent out the set of patches he intends to submit as the queue of EFI changes for what will become the Linux 4.7 kernel. He noted of this queue, "this is probably the biggest EFI pull ever sent, and there quite a few different topics covered."
An argument has taken the form of a verbal running gun battle at our shop, depending on who's working that day. Does training a student in the use of Linux deprive them of valuable, life-long learning opportunities? I mean, it's hard to argue the value of being able to delve into the registry and edit the offending subkeys and values that are allowing your banking information to be spread across three continents. How are they to learn the ins and outs of virus and malware protection and for Pete's sake, do it for the children. Make sure they learn how to use Malwarebytes. For the love of Linux, please don't fail these kids.
eWEEK: As the OpenStack Summit kicks off, Red Hat reveals some major customer wins as well as a new milestone for trained professionals.
http://cyborg.ztrela.com/ I've been using it for about a year or so now and I like it better then Backtrack and Black Box. Tell me your thoughts.submitted by /u/Ackrynom
So I read most of the comments here on this article and honestly, it just confused me more.
Some say Canonical rebuilds the Universe packages in the next cycle from Debian Testing (which should fix the security issues of apps in that repository like VLC). On the other hand, there are mentions of the packages being not supported at all after 9 months, etc.
I am just plain confused. Can someone please give some context and ELI5? I was under the impression that everything in LTS is you know, long term supported.
I just love Ubuntu, it has been rock solid for me since my Linux start but if those security issues are really concerning, I wouldn't mind considering switching to OpenSuse or Fedora.
Edit: Also if this security issue is true and it really means that apart from Main, everything is only supported for 9 months, what then is the major difference between Ubuntu LTS releases and non-LTS ones? I will simply just keep updating to newer versions and be equally stable and secure then! Correct?submitted by /u/tinycosmicdust
Linux.com: General office productivity tools are those that enable you to work with documents and files and keep an efficient day-to-day work flow. Some might think these tools would be missing from the Linux ecosystem. I am happy to report, the naysayers are wrong.
I've primarily been exposed to the Windows and Mac OS X operating systems. But now I want to learn about Linux. Specifically CentOS. This is so I can be well rounded and more marketable.
What are some good books or websites that I can read, that would be very beneficial?submitted by /u/Gohighflier
Chromium OS for SBC project, through Dylan Callahan, informs Softpedia about the immediate availability for download of the Chromium OS for Raspberry Pi 3 single-board computers.
The first community supported x86 hacker SBCs not backed by Intel or AMD are pricier than most ARM SBCs, but offer faster CPUs and competitive power drain.
The first x86-based community supported hacker SBCs not backed by Intel or AMD have reached market, offering higher prices than most ARM SBCs, but featuring faster processors and competitive power consumption. The Kickstarter-backed newcomers, all of which run Linux or Android, include the now-shipping JaguarBoard, the soon to ship UP board, and the Udoo X86, due in November.


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AATA News
Discover the latest news about AATA and what others are reporting about us worldwide.
Archangel Provides Trees for Europe's First Redwood Forest
Forty coast redwood trees were planted on Monday at the Eden Project in the south-west of England, the first time a "forest" of these big friendly giants from north America has been introduced to Europe.read more
Archangel on American Variety Radio
Archangel's David Milarch was interviewed on American Variety Radio, hosted by Court Lewis, in a discussion about the genesis of Archangel Ancient Tree Archive, its mission and activities.read more
Plants & Preservation
Our David Milarch contributed to this fascinating story of how research centers are preserving the genetic basis of plant life in order to help humans adapt to future global climate change.read more
Archangel Press Kit Released
We the updated information presented here, and with your support, the outcome that we can create together is truly unlimited.read more
The film, Moving the Giants premieres
Moving the Giants is a film about the life's work of Archangel's David Milarch. It premieres November 7 at the Banff Mountain Film Festival, and online via Video On Demand. Proceeds support Archangel's work.read more
Jurassic Bark: Ancient Irish Trees Live Again
Archangel Ancient Tree Archive collected 130 of the oldest trees in Ireland. These iconic trees, along with California redwood clones, were propagated and reintroduced into the Irish landscape through the help of our friends.read more


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New breed of orca takes to the water
Steers like a plane, breaches like a whaleSALLY DOMINGUEZ
Relevant offers
A New Zealand designer is making waves with a jetboat-hybrid that steers like a plane - but leaps out of the water and breaches like a whale.
The Seabreacher is already being operated as a tourist activity in Queenstown, has been approved by maritime authorities here and Australia and is beginning to take bites in the market elsewhere.
The machine could be described as a fast-planing raceboat, or alternately as a fully sealed jet-ski-engined sea missile that can plunge two people under the water at 60km/h and then hurl them into the sky.
Liveried as a killer whale or in newer iterations as a metallic hammerhead or great white shark, it's a recreational showstopper that not only defies description, but also gravity and basic nautical conventions.
New Zealand-born, United States-based designer Rob Innes describes the Seabreacher as a "custom-designed hot rod for the water".
To prove his point, he hauls himself into the killer whale-liveried "Y" model - dubbed Orca - with its 260 horsepower (194kW) supercharged engine, roars away, executes a dive, and leaps so high that for a majestic moment, no part of the 5.2-metre, 658kg craft is touching the lake.
Mr Innes and business partner Dan Piazza are keenly involved in hot rods and performance boat racing. The hand-crafted Seabreachers are made in their Northern Californian headquarters, Innespace productions, and show the meticulous attention to detail and performance capability characteristic of hot rods.
Each Seabreacher, custom-sculpted in fibreglass and Kevlar and fitted with a pneumatically sealed fighter jet-style polycarbonate canopy, takes three months to build and costs upwards of US$65,000 (NZ$77.800).
It has three axes of control, like a plane. Yaw is controlled by the driver's legs, roll determined by hand levers, and pitch set by pointing or flexing feet held into bindings on the pedals.
The Seabreacher is legally categorised as an inboard powerboat. It draws air for its three-cylinder, 1500cc four-stroke Rotax jet-ski engine - and for its occupants - via a snorkel mounted behind the dorsal fin.
Positive buoyancy means no matter how you dive, roll or land - and Mr Innes says he's done all that and more in testing - it will end upright.
Currently, Queenstown's Hydroattack claims to be the only place in the world to offer commercial tours of the vehicle, launched by locals David Lynott, Lee Excell and Oliver O'Neill with Mr Innes' support last year.
Hydroattack is also the official distributor for Seabreacher in New Zealand. It is certified by Maritime New Zealand and Maritime Australia as a recreational watercraft
Pricing is expected to be around the $100,000 mark for Australian customers, depending on customisation required.
- The Dominion Post
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Wellington police investigating homicide in suburb of Strathmore Park
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Wellington bar owner caught making sex jokes during liquor licence hearing
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Wellington and Canberra look to become sister cities
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Porirua has dried up in the past 24 hours
Appeal chucked out for man who claimed he raped his wife while asleep
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Wellington police investigating homicide in suburb of Strathmore Park
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Hutt Valley and Porirua suburbs bask in glow of Wellington property boom
Porirua has dried up in the past 24 hours
Wellington bar owner caught making sex jokes during liquor licence hearing
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School holiday entertainment and fun for everyone
Google turns NZ streets into a giant game of Pac-Man
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Another former All Black gives super-city plan a kicking
Tuatara's Wellington brewery snapped up for $1 million
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How soon will you visit the new war memorial park?Related story: War memorial park all but completed


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Click on a thumbnail to go to Google Books.
Just Behave, Pablo Picasso! (edition 2012)
by Jonah Winter, Kevin Hawkes (Illustrator)
Work details
Just Behave, Pablo Picasso! by Jonah Winter
No current Talk conversations about this book.
This is a biography of Pablo Picasso. He faced many struggles as he began painting. No one was interested in buying his art work, but that did not stop him from doing something he loved.
Personal Reaction:
The biography was very age appropriate. It shows that children can follow their dreams.
Classroom Extensions:
1. Let the students draw something they are passionate about.
2. Have the students tell a fact about someone famous who followed their dreams.
This biography written in simple language, but rich, tells the story of Pablo Picasso and how he became worldwide well recognized Artist during the times he lived in Spain and France. The beautiful and colorful illustrations portrait Pablo's transformations in different styles. The realistic illustrations demonstrate how he went from realism, surrealism, expressionism to cubism and abstract art with real paintings. Fantastic!
I really enjoyed this book for many reasons. The first reason I liked this book was because of the illustrations. They were beautiful watercolor paintings and they showed the work of Pablo Picasso so it really helped the words and pictures connect. The book is about Pablo Picasso, who I enjoyed reading about as an individual character. He was very determined with his work, he didn't listen to the critics and painted anything he wanted. Another reason I liked this book was because of the writing. Sometimes the words were written in different font, bolded, written sideways, etc. throughout the story which really helped me stay engaged in the story. The main idea this book is to never let anyone tell you what to do, and keep doing what you love. Picasso didn't listen to all of the critics and he is now known as one of the most famous artists.
The book Just Behave, Pablo Picasso! By Jonah Winter is a fantastic biography about the struggles that artist Pablo Picasso went through when first becoming a popular artist. I really enjoyed not only the meaning behind the book, but also the illustrations and words in it. The main idea of this book is to not let other's opinion on you or your work discourage you from being yourself. All children in their life eventually experience hearing hurtful words from classmates at some point in their life, as children have many opinions and sometimes forget that their words could hurt someone's feelings. While Pablo Picasso was talked down upon for pursuing different works of art than people wanted him to, he did not let that get to him. People would say that his work did not make sense, and his response was, "the world today doesn't make sense" (30), which is extremely true because every single day the world is changing, and no two days will ever be the exact same. If you lived everyday the same exact way, life would be boring and tiresome, so why should his artwork always be the same? Pablo kept creating works of art until eventually people were in awe of his creative style of artwork and finally appreciated it. Throughout this book there are certain words that are in bold or capitalized to help put emphasis on the meaning of the words, which makes it really hook the reader's attention and keep them engaged. The illustrations in this book are simply amazing, as they all look like real paintings. The colors on each page really catch your eye and show the beauty of the paintings.
In Just Behave, Pablo Picasso!, a young Pablo Picasso has been in love with painting. The people around him love his paintings as well, but they will not allow Pablo's talent to grow. Tired of being creatively held back, Pablo Picasso starts to paint different images than what he was known for. Picasso's new painting styles are met with anger, but people eventually come around. The illustrations in the book look like paintings; the images are fitting for a book about Pablo Picasso.
References to this work on external resources.
Wikipedia in English
Amazon.com Product Description (ISBN 0545132916, Hardcover)
An inspiration to anyone who's ever felt judged!
"One day the world is a peaceful, lovely landscape painting... The next day - BLAM! - Pablo bursts through the canvas, paintbrush in hand, ready to paint something fresh and new."
Pablo Picasso may have been one of the most famous artists of the 20th century, but that doesn't mean he painted what people wanted him to paint! In fact, some people hated his paintings, and called them "ugly!" and "terrible!" -- something many kids can relate to. But Picasso didn't listen to all those people, and kept on working the way he wanted to work, until he created something so new, so different... that people didn't know what to say!
For every young artist who's drawn something other kids think is "ugly," this story of rebellion and creativity is sure to inspire.
(retrieved from Amazon Thu, 12 Mar 2015 18:12:14 -0400)
"Pablo Picasso may have been a world-famous artist, but that doesn't mean no one ever called his artwork "ugly." Any kid who's been told what to draw, or heard mean things about something they made, will relate to this story about how Pablo faced down his critics and made something truly original."--Jacket flap.… (more)
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Wis. cop paralyzed in shooting dies from injuries
A Wis. deputy died Monday, after succumbing to complications stemming from a gunshot wound he received in a shootout with a suspect in 1991
By PoliceOne Staff
POLK COUNTY, Wis. — A Wis. deputy died Monday, after succumbing to complications stemming from a gunshot wound he received in a shootout with a suspect in 1991.
According to ODMP, Deputy Sheriff Mike Severson of the Polk County Sheriff's Office was shot on April 19, 1991 while attempting to apprehend a suspect wanted for a shooting the day prior.
Another officer, Deputy Sheriff Allen Albee, was killed when the suspect opened fire with a .32 caliber handgun.
Severson suffered a wound to his spinal cord, paralyzing him from the neck down, ODMP reported.
Other deputies returned fire and killed the suspect.
Severson was 27 years old at the time of the attack, CBS Minnesota reported. He was 51 years old at the time of his passing.
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Join the discussion
PoliceOne top 5
1 Dallas police to be outfitted with 'sponge guns' as less lethal option
2 Commissioner: Boy shot by Baltimore officer will 'absolutely not' face charges
4 Videos, photos: 5 officers injured in Seattle May Day protests, 9 arrested


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SB Nation
The 5 NFL teams who won the 2016 Draft, according to a college fan ignorant of the NFL
SB Nation
Shon Coleman, OT, Auburn. 3 (93). Cody Kessler, QB, USC. 4 (99). Joe Schobert, OLB, Wisconsin. 4 (114). Ricardo Louis, WR, Auburn. 4 (129). Derrick Kindred, S, TCU. 4 (138). Seth DeValve, TE, Princeton. 5 (154). Jordan Payton, WR, UCLA. 5 (168 ...
Auburn Journal
That joke is so tired it's time to put it to rest
Auburn Journal
... hilarity, wouldn't it be great if we all stopped telling jokes that insult other people based on how they're different from us? Because, really, those jokes aren't funny. They never were. Tricia Capers is an award-winning poet and reporter at the ...
Lynch's ascension to NFL comes on wing-T offense, loyalty and commitment
Journal Advocate
On the morning of the signing date, George O'Leary's staff at nearby Central Florida got the word that a quarterback prospect was switching to Auburn. Charlie Taaffe ... He jokes that maybe the Broncos should thank him for preserving Lynch's arm. "I ...
Delivering a great graduation speech
Daily Illini
Tim Cook, Apple's CEO, phrased it like this in his 2010 Graduation Speech at Auburn University: "Trust your intuition, and then work with everything you have to prove it right." ... Jokes followed by more jokes or random topics can detract from a good ...
Gridiron Now
A'Shawn Robinson says 'it's cool looking old.' And who'd argue with him?
Gridiron Now
We have all heard the jokes about former Alabama Crimson Tide defensive tackle A'Shawn Robinson — who turned 21 in March — looking like a 40-year-old man. And he's fine with that. Robinson sports a beard and a shaved head, and when he wants to ...
Hartford Courant
Living The Dream: UConn's New AD Grew Up In Sports
Hartford Courant
Cynthia Benedict jokes that her son attended his first football game before he was born. She was pregnant with David when she attended a game in Arizona involving her husband's team, Tempe High School. Months after he was born, he was at the football ...
Bleacher Report
2016 NFL Draft Grades: Full Day 3 Report Card
Bleacher Report
Some of the scouting reports get a tiny bit vague. Some of the grades get a little broad. But there's plenty of insights, analysis, stats, criticisms and jokes for some of last year's greatest collegiate stars and, in all likelihood, a few of next year ...
Auburn Citizen
Raiders owner to Las Vegas: Build it and we will come
Auburn Citizen
He made a few jokes before delivering a $500 million commitment to a new stadium in the city for his team. Then the owner of the Raiders got serious about the prospects of getting fellow NFL owners to allow him to move from Oakland to a city the league ...
Bleacher Report
SEC Extra Points: NFL Draft Will Again Prove SEC's Power
Bleacher Report
The dreams of many will come true this weekend, when football players from around the country will receive phone calls from professional football organizations and offers to play the sport they love for a living. Many of them have been starring in the ...
Brightening the Spot Light: Local theater veteran overhauling Arc of Seneca Cayuga's arts program - Auburn Citizen
Auburn Citizen
Brightening the Spot Light: Local theater veteran overhauling Arc of Seneca Cayuga's arts program
Auburn Citizen
AUBURN — Thursday afternoon, just before rehearsal starts, Spot Light Studio is utter chaos — one person sings "The Star-Spangled Banner," another person is telling jokes, a pair are tap dancing, and another pair are practicing songs in front of a ...
Google News


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35 points
Recent Activity
Question Asked: Why are the headlights flashing off and on as soon as the doors open w/ car off?
September 18, 2011, 08:24 PM
My boyfriend turned off his car today and as soon as he took the keys out of the ignition and opened the car door, his headlights started flashing off and on. They eventually time out and go off. It just randomly started happening today. The battery is brand new, so he has been unpluging the battery everytime we leave it for long. Could it be a relay switch? I think is has something to do with his car alarm, because thats what his alarm does when it goes off the only difference is, the car isn't making the beeping noise it normally would if the alarm was going off.
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|1 pushrod
|6 americanautoair
|2 stevieray1
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|5 Wally Jay
|10 devonshire


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- Snorkeling cruise to Cades Reef
- See marine life including barracudas, moray eels, sting rays, and reef sharks
- Lunch included
- Complimentary hotel pickup and drop-off
What You Can Expect
After pickup from your hotel, you'll set sail to Cades Reef. Once anchored, explore the marine life of Antigua. Stretching over 2 miles, you're likely to see some larger sea animals, including barracudas and moray eels among the soft and colorful coral while snorkeling at Cades Reef. Enjoy lunch on a beautiful beach before sailing back to your hotel.
Customer Reviews
September 2012
The crew of our sailboat was the best , the food was good and the snorkeling was outstanding. The crew made sure that everyone was safe while out in the water and Victor saved my wife from a jellyfish.


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Discover a selection of top forums events free! p34 on the internet. Come to share your passion on forums events free! p34 and meet other fans of events free! p34. Then, why don't you create your own forum of events free! p34 ?
Free Forum : Help and support to Forumotion users. Create and administrate a forum. Discover our guides, tutorials, tips on the Forumotion's Support Forum. Free Forum : Help and support to Forumotion users. Create and administrate a forum. Discover
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It's time to get into the swim of things again.
RIPON -The Kinder Garden Boutique in downtown Ripon is all about family – theirs, ours and yours.
If loan modification efforts for struggling homeowners prove unsuccessful 2011 could be when the long-feared "shadow inventory" of home foreclosures hit the San Joaquin County market.
First, it all started with a move to Los Angeles and a dream to make it big.
Ed Powers was 24 years old when he arrived in Manteca with a dream.
Scenes from Sunday's "Church under the Sun"
Affordability - in terms of being able to secure housing by renting or buying - is showing signs of starting to erode once again in Manteca.
The midway, the numerous exhibits, foods, and the concerts are part of the 2010 San Joaquin County Fair.
LATHROP - The firefighters did not even need to ask for donations. Motorists at the intersection of Louise Avenue and Harlan Road in Lathrop kept the 10 volunteers from the Lathrop-Manteca Fire District constantly on their toes with their donations from 9 a.m. to about 1 p.m. Saturday.
A barbershop quartet comprised of Manteca High students has made their mark during the past school year from singing their rendition of the National Anthem at area events to a talent show and end of the year concert.
Scenes from the 91st annual MRPS festa.
Tyler Gales sauntered onto the Give Every Child a Chance bus in the parking lot of Best Buy with an ear-to-ear to grin.
The Trails of Manteca - the biggest completely residential housing project ever envisioned for the city - is getting ready to move to the environmental study stage.
At the tender age of 9, Shari McCallister raised livestock for the fair competition.
Sail away to Puppet Island with Captain Book and his hilarious crew with Tony Borders on Wednesday, June 16, at 3:30 p.m., the Manteca Branch Library.
Page 650 of 869
Erika Miranda loves art.
The decision by the Manteca Unified board to bring the Acorn League back in house after 10 years of being run by a non-profit might ...
When it comes to inserting advertisements in the mail – namely, monthly utility bills or annual dog license renewal notices – the City of Ripon is currently ...
STOCKTON - It was a good week for Manteca High.
The lack of a school funding mechanism for thousands of new homes expected to be built south of the 120 Bypass may mean year round ...
Tydus Verhoeven is impossible to miss.
I once interviewed a cafeteria "lunch lady" for an article I was writing about a specific food program that she was in charge of. The ...
The Manteca High girls' soccer team will be kicking for a lot more than just goals when they host Lathrop High on Monday, April 25.
An off-duty federal agent went to the aid of a 51-year-old motorist Wednesday morning as he was being attacked by two Manteca men.
There is perhaps no smugger environmentalist than one who resides in San Francisco.
Get ready for the invasion of the food trucks.
Lyza Stevens had a few things on display Thursday night at the Sierra High School's Evening of the Arts.
Editor's note: This is part of an occasional series profiling the religious leaders in Manteca, Ripon, and Lathrop.
A simple and relatively inexpensive way to expand California's available water is to modify spillways on reservoirs.
Is Lathrop poised to be the new expansion ground for Silicon Valley?
Page 8 of 17
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View which countries have been approved for each type of Gavi support as of 30 November 2015
Since 2007, countries have immunised 22 million children with a 2nd dose of measles vaccine with Gavi support. Gavi-funded measles campaigns have helped vaccinate another 67 million children in countries considered at high risk of measles outbreaks.
More facts...
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Author Title Type [ Year]
Filters: Author is Peggy Rosin [Clear All Filters]
In Press
A pre-kindergarten curriculum supplement for enhancing Mainstream American English knowledge in non-mainstream American English speakers. Language, Speech, and Hearing Services in Schools. PDF of accepted manuscript (293.58 KB)(In Press).
Dialect mismatch and its implications for academic achievement. Annual Conference of the American Speech-Language-Hearing Association. Slides.pdf (2.31 MB)(2013).
Increasing awareness of "school talk": A focused intervention for pre-kindergarten children who speak a non-mainstream English dialect. The Symposium for Research in Child Language Disorders. Poster.pdf (1.79 MB)(2012).
TALK: A pre-kindergarten readiness program for non-mainstream English dialect users. Annual Conference of the American Speech-Language-Hearing Association. Poster.pdf (2 MB)(2012).


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On Ap sense Burk wrote :
"BTW, its a great day and donations are rolling in from supporters that no you are making up this hoax scam. One fellow, in show of support against you, donated and will be gifted 4 28-count cases of Bionaid (They, like thousands of others, love Bion aid) in gratitude for his $2,800.00 donation!
Nov 14th 2012 10:33"
So, were are these thousands of others consurmers who loved Bio naid, not here and not on internet so far !
A mystery donator gived $2,800.00 donation and will be gifted of 4 28-count cases of Bionaid.
So, why Claus Nicolae Nielsen of Denmark who is the European distributor of Bionaid, Rodney of England who is the U.K. distributor of Bionaid, and Clarence Lee, the Asian distributor of Bionaid didn't received the bottles they had paid for ?
Anonymous Coward 25993639
I bet that Burk prefers to keep the water for him, and not send it to whom they own it. Sad guy.
Anonymous Coward 4724478
I doubt it. Elder lives on V.A. disability in his widowed Mom's home outside Chattanooga in Ringold, GA. Likely the water now in the bottles is right from their tap and then they stick the labels on. If the water is so fabulous why is Elder so disabled drawing his check? It didn't work for him or his Mom.They seem to have Alzheimers or something as it is not like being in contact with any normal business.I do recall Elder barking about Len Horowitz buying his Bionaid and was just his own water from his place in Hawaii in the bottles.Len was cutting him out of buying the water from him or so he claimed at the time even here on GLP. It appears Elder was doing the same thing or took up the practice.
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Truth behind chemo: 'These drugs were derived from WWI chemicals'
Wisconsin city passes ordinance to fine parents of bullies hundreds of dollars
Donald Trump is now the Republican nominee Trump to stand unopposed as John Kasich ends Republican nomination bid
5/04/2016 -- New Fault + Large crack in ground forms in Pennsylvania / East Coast USA
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Pharmacists at Jena University develop three new drug candidates against inflammation
It is something like the police force of our body: the immune system. It disables intruding pathogens, it dismantles injured tissue and boosts wound healing. In this form of 'self-defense' inflammatory reactions play a decisive role.
But sometimes the body's defense mechanism gets out of control and cells or tissues are affected: "Then excessive reactions can occur and illnesses along with them," Prof. Dr. Oliver Werz of the Friedrich Schiller University Jena says. He gives asthma, rheumatism, arteriosclerosis and cancer as examples: "For many of these diseases there are only few effective therapies without severe side effects."
But the team of researchers working together with the Jena pharmacist has now developed three active agents which may be able to improve the healing of inflammatory illnesses better in future. The scientists present the potential therapeutic agents in renowned scientific journals. The agents are able to suppress a key enzyme in the body's own cascade of inflammation.
"The enzyme called 5-LOX plays a pivotal role in the synthesis of so-called leukotrienes, which are part of numerous immunological and inflammatory processes," Prof. Werz explains. Hence, the effort to prevent the synthesis of leukotrienes has been the focus of international research for inflammatory therapy for a long time. "Thousands of publications on the subject have emerged in the last 30 years," says Werz. But apart from one exception none of these efforts have made it to the stage of an approved medication. Either the efficacy of the substances was poor or they were accompanied by unwanted side effects.
As a reason behind this, the Jena pharmacist sees the insufficient understanding of cellular regulation of the leukotriene biosynthesis and the lack of knowledge of the molecular mechanisms of agent and target molecule. "Instead of testing a number of substances to see if one of them might show any activity, we took a close look at 5-LOX and tried to find where exactly this enzyme is vulnerable and what the agents, which can interact with our target molecule, should look like," Werz describes the basis-orientated approach.
In this way the scientists of the Jena University together with partners from Austria, Italy, Turkey and Greece, were able to identify three possible agents. So for instance, a so-called benzoquinone proved to be an effective inhibitor of the 5-LOX. This is a substance which is derived from the natural product embelin from the "False Black Pepper"-plant (Embelia ribes). The pharmacists were able to show that this substance fits exactly into the active center of the enzyme and thus blocks its function. "This specifically only happens with 5-LOX," Werz says and stresses that benzoquinone may practically show no side effects.
A related substance of the red-violet natural dye indirubin, called 6-BIO, proved to be similarly promising. For this substance, the Jena researchers were able to clarify the mechanism of action as well: the 6-BIO inhibits the enzyme 5-LOX by blocking receptor sites for other molecules which are necessary for it to work properly. "In addition, 6-BIO also intervenes with the synthesis of additional inflammatory factors – the cytokines implying additional synergistic effects." This is why 6-BIO could for instance be of interest for the therapy of Alzheimer's disease, in which cytokines are also playing a role.
The third possible active agent from the Jena University's laboratory does not inhibit the 5-LOX itself, but it deactivates a helper-protein, which the enzyme needs for its effectiveness within the cell. The researchers identified this active agent, a benzimidazole with the short term BRP-7, by a virtual screening in a library consisting of nearly three million substances. "From our point of view all three of the drug candidates are very well suited to a further development as medications," Prof. Werz summarizes. However, for this, the support of the pharmceutical industry is needed.
Original Publications:
Schaible AM et al. Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase. British Journal of Pharmacology 2014 (DOI:10.1111/bph.12592)
Pergola C et al. Indirubin core structure of glycogen synthase kinase-3 inhibitors as novel chemotype for intervention with 5-lipoxygenase. Journal of Medical Chemistry 2014 (DOI:10.1021/jm401740w)
Pergola C et al. The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP). British Journal of Pharmacology 2014 (DOI:10.1111/bph.12625)
Prof. Dr. Oliver Werz
Institute of Pharmacy
Friedrich Schiller University Jena
Philosophenweg 14, 07743 Jena
Phone: ++49 3641 / 949801
Email: oliver.werz[at]uni-jena.de
Dr. Ute Schönfelder | idw - Informationsdienst Wissenschaft
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text:
Hacked By: selectLOL
Hack Information:
Hackmenu (Backslash(\) Open/Close): 1 Toggle godmode - 2 Win level - 3 Spawn plumber (1-14)
Game Information
Create clones and utilise their special abilities all whilst controlling them simultaneously in this crazy puzzle-platformer.
Cheats: Key Hacks: Press [1] All Skills - [2] Low Gravity - [3] Gray...
Hacked By: leverage419
Cheats: Hackbar: Press [Z] Gold +1000 - [X] Toggle Health - [C] Togg...
Hacked By: leverage419
Cheats: Hackbar: Press [1] Teleport to the Left - [2] Teleport to th...
Hacked By: leverage419
Cheats: Hackbar: Press [1] All Balls Unlocked - [2] Life - [3] Invin...
Hacked By: leverage419
why cant play selectLOL is motherfock!plz dont -1 me :(
why your a bottom hole too
Exactly, its a remix of Super Mario Bros and other platform games.
good game
its da fugly face deal with it
8 was my fav XD
found BUG
1 comment ONly? -_- version of mario
Registered Users: 466123
Hacks Played Today: 218511
Total Hacks Played: 772166018
There are 1606 users online
19 Members, 1587 Guests


text:
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[Blind Gossip] This girl was at the top of her game just a couple of few years ago. However, she is hardly working at all now, and it's creating major problems in her relationship with [Read more…]
The Much Bigger Story Behind The Seizure
This is a BlindGossip.com EXCLUSIVE. In keeping with our Terms of Service, we ask media outlets and bloggers and social media users to clearly and properly credit and link to BlindGossip.com when discussing this story. Thank you for your professional cooperation!
[Blind Gossip] You may be aware that a celebrity is concerned that his cell phone was seized by police. He knows that there are photos and film clips of him on there in various states of undress and doing various drugs. However, there is a much bigger story behind the cell phone that only we know about! [Read more…]
Models Actresses and Johns
[Blind Gossip] You probably remember Kristin Davis as the New York City Madam who blew the whistle on Client #9, Eliot Spitzer, the former Governor of New York.
While Spitzer liked role play [Read more…]
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[Blind Gossip] There is a really interesting sapphic brawl going on right now among several female celebrities! [Read more…]
You Are A Total Moron
[Blind Gossip] This actress is half of a married celebrity couple. He is a much bigger star than she, and most of the films from which you remember her probably starred her husband and featured her in a much smaller role.
With that discrepancy in fame, there [Read more…]
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[Blind Gossip] This very famous Singer broke up with this Business Guy over a year ago. He was really hired (Yes, hired) as more of a guardian than a mate. The public was surprised when they broke up, though, because they saw him as such a stable influence in her life. Not really! [Read more…]
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[Blind Gossip] This naturally brown-haired TV actress was thrilled when she found out that she was pregnant for the first time.
She was getting ready to announce the pregnancy [Read more…]
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[Blind Gossip] The cast of a successful cable television drama series has a really dramatic love affair playing out on the set [Read more…]
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[Blind Gossip] When asked why she doesn't work more, this famous actress will say that she is concentrating on her family. Privately, however, she is [Read more…]
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Paid Friends 3
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Sometimes, just being fun to be around is a currency that translates into social invitations, as it has for a bicoastal producer I know. [Read more…]
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The shallow actress was asked about shopping after Thanksgiving. A friend jokingly asked her if she was planning to battle the crowds on Black Friday. [Read more…]
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This Actress is a fan favorite, but you'd never know it by the way the network refused to promote her. [Read more…]
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[Pop Bitch] Which young actress, highly paid to front a cosmetics firm, has been costing them a fortune in re-touching and re-shoots as "she doesn't want to look as if she has been airbrushed"?
Cosmetics Company:
She Lied About The Phone Photos
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She'll Have Something New To Cuddle Next Year
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This watercolor sketch of Hiroshima by Shigehiko Ishikawa measures 9 5/8 x 13 3/4 inches, is signed, titled and dated Aug. 11, 1951. Artist signature on reverse.
Etching, image size 9 3/8 X 6 1/2 inches, pencil signed.
A fine sketch by Dexter Dawes measuring 10 3/4 x 7 1/2 inches on medium weight drawing paper. A small unfinished sketch of trees is on the reverse. Dawes spent many summers in the Marlboro, NH area drawing and painting the incredible natural beauty that surrounded him.


text: Jessica Simpson, Eric Johnson wed in Santa Barbara: People Reuters Posted at Jul 07 2014 08:36 AM | Updated as of Jul 07 2014 04:36 PM Jessica Simpson married former NFL player Eric Johnson in southern California on Saturday, People magazine reported. Simpson, 33, and Johnson, 34, tied the knot at the San Ysidro Ranch in Santa Barbara, according to the magazine which received confirmation from the couple. "We are overwhelmed with complete happiness and love having made our eternal commitment," Simpson and Johnson said in a statement to People on Saturday. The couple was joined by more than 250 guests, including Simpson's sister Ashlee Simpson and her fiancé Evan Ross, Jessica Alba and Donald Faison. The couple have two children, one-year-old Ace who served as a ring bearer and Maxwell, 2, who was a flower girl. Simpson, a pop singer and Weight Watchers spokeswoman and Johnson, a former San Francisco 49ers tight end, began dating four years ago and became engaged in November 2010. Share Facebook Twitter GPlus LinkedIn Pinterest Kakaotalk Viber WeChat Read More: Jessica Simpson eric johnson /sports/05/03/16/energy-execution-will-be-keys-to-game-5-says-black/entertainment/05/03/16/drake-joins-forbes-list-of-top-five-richest-hip-hop-stars/sports/05/03/16/look-tnts-castro-finally-gets-his-diploma/video/nation/05/03/16/days-before-elections-duterte-maintains-lead-in-survey/video/nation/05/03/16/how-verbal-tussle-among-candidates-affects-voters


text:
People not impressed by manifestosSeveral social activists, farmers, and neutral voters have said that they are not impressed by the election manifestos of the political parties as they feel that the documents do not have vision for future welfare of people. They feel issues such ... The Hindu, 5 days ago
Manifestos do not have vision for future welfare of people - The Hindu, 5 days ago
Vijayakanth slams MK's CM aims, at 92
Kulithalai: In a hard hitting broadside against DMK president Karunandihi, DMDK chief Vijayakanth yesterday mocked at him for aspiring to be Tamil Nadu's Chief Minister for the sixth time. Stating that people of Kulithalai are good, he said they ...News Today, 1 week ago Vijayakanth Slams Karunanidhi For Aspiring To Be Chief Minister At 92 NDTV, 1 week ago Tamil Nadu polls 2016: Vijayakant mocks DMK chief Karunanidhi for aspiring to be CM at 92 DNA, 1 week ago Vijayakanth slams DMK chief for aspiring to be CM at 92 Press Trust of India, 1 week ago
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Lok Satta state president alleges corruption at district hospital
Lok Satta Party state president A. Palanikumar, who has been campaigning against corruption, has find himself reportedly at the receiving end when his wife was admitted to District Headquarters hospital for delivery. Mr. Palanikumar had ...The Hindu, 1 week ago
Justice Rao Takes Charge As Madras HC Judge
CHENNAI: Justice Nooty Ramamohana Rao, former judge of the High Court of Judicature at Hyderabad for States of Telangana and Andhra Pradesh was sworn in as Judge of the High Court of Madras by Chief Justice Sanjay Kishan Kaul, at the HC campus on ...New Indian Express, 1 week ago
Celebrating Sheik Chinnamoulana's musical legacy
Kasim and babu, grandsons of nagaswaram legend Sheik Chinnamoulana, on the objectives of the two-day anniversary celebrations in Tiruchi As a helicopter hovered overhead, a saxophonist parachuted from the aircraft, playing a piece in the major ...The Hindu, 3 weeks ago
Neglected father finally gets justice
Coimbatore: An 85-year-old man from Vilankurichi had in 2006 distributed his property worth 18 crore among his three sons equally, with the condition that they give him 10,000 each month to cover his medical expenses. When they refused to pay heed ...Times of India, 4 weeks ago
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Contributed by NAMPA / PTI. Chennai, Apr 1 (PTI) A court here has convicted former Chairman and Managing Director of Indian Bank M Gopalakrishnan in yet another case of corruption and sentenced him to two years rigorous imprisonment. The court ...Namibia Press Agency, 4 weeks ago Former Indian Bank CMD convicted in yet another graft case Moneycontrol.com, 4 weeks ago
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The Hindu Young World Painting Competition held in Madurai recently saw over 200 participants take part. From over 2000 entries sent during the preliminary round, 400 entries were given a chance to showcase their skills at The Hindu Young World ...The Hindu, 1 month ago
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The recently inaugurated Collectorate here is becoming an eyesore and unpleasant to visit due to the unattended garbage and foul smell constantly emanating from the toilets situated in all the first six floors. Rubbish and food wastes can be seen ...The Hindu, 1 month ago
Dental health awareness camp held
A dental awareness camp was held at the Sri Meenakshi Government College for Women recently. Dr Jibreel Oysul, head of dental surgery, Meenakshi Mission hospital, led the dental awareness programme for the students and staff of the college. He ...Times of India, 1 month ago
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We expose slave masters and people smugglers in suburban Britain.
A journalist pays the ultimate price in Syria
04 Jul 2012 12:53 GMT | Politics, Europe, US & Canada, Japan, United States
The European Parliament rejected by a wide majority the Anti-Counterfeiting Trade Agreement (ACTA), an international copyright deal which, critics say, threatened internet freedom.
Only 39 lawmakers voted in favour of ACTA on Wednesday; 478 rejected it, while 165 abstained, killing off the EU ratification process. This might give an incentive to other signatories to also walk out, forcing the renegotiation or the outright abandonment of the agreement.
The conservative European People's Party (EPP), the largest group in the EU assembly, unsuccessfully tried to postpone the vote until the European Court of Justice (ECJ) delivers a verdict on whether ACTA really poses a risk to civil liberties.
"No emergency surgery, no transplant, no long period of recuperation is going to save ACTA: it is time to give it its last rites, it is time to allow its friends to mourn and for the rest of us to get on with our lives," British socialist David Martin, who drafted parliament's opinion on ACTA, said before the vote.
"Rejecting the ACTA flat out, without trying to address concrete concerns, after years of negotiating, does nothing to handle the serious threats to European jobs and enterprises ACTA intended to solve," EPP member Christofer Fjellner complained afterwards.
By contrast, lawmakers from the Green group, which campaigned vigorously against the deal, waved banners saying "Hello Democracy, Goodbye ACTA."
The agreement had been signed by Australia, Canada, Japan, South Korea, Mexico, New Zealand, Singapore and the United States, as well as by the EU and its member states. It establishes global standards against counterfeit goods, non-licensed generic medicines and online piracy.
'ACTA is going nowhere'
In a debate Tuesday, Martin said that its wording was too vague and could lead to abuse. For example, he raised the possibility that internet service providers could be forced to police their customers' behaviour to prevent online piracy.
Oxfam, a development non-governmental organization, also charged that ACTA risked denying people in poorer countries access to cheaper medicines.
"ACTA could have made life-saving drugs much costlier for the world's poorest, resulting in devastating consequences for their health. With Europe's rejection, we're now hugely relieved that ACTA is going nowhere," said Oxfam spokeswoman Leila Bodeux.
EU Trade Commissioner Karel De Gucht, who represented the bloc in ACTA negotiations, had in vain tried to reassure lawmakers that the agreement would not have forced any change in EU legislation.
"Since our freedoms are not threatened by our current laws, our freedoms will not be threatened by ACTA," he said in debate Tuesday, while adding that there would be "no quick fixes" after a parliamentary 'no' vote.
"With the rejection of ACTA, the need to protect the backbone of Europe's economy across the globe, our innovation, our creativity, our ideas - our intellectual property - does not disappear," he added in a written statement on Wednesday.
Even after the parliamentary rejection, the commission still intends to wait for the ECJ to have its say on ACTA and then "consult with our international partners on how to move forward," De Gucht said.
Mass demonstrations have taken place against ACTA in several European countries, leading governments in Germany and elsewhere to perform a policy U-turn, halting national ratification procedures after having signed the agreement in January.
The EU parliament also received a worldwide petition against the agreement, signed by 2.8 million people.
Since obtaining more powers under the 2009 Lisbon Treaty, the EU assembly has taken a far more assertive stance. Most notably, it struck down an anti-terrorism deal with the United States on sharing bank data in 2010, forcing the EU commission to renegotiate it. dpa alv ncs Author: Alvise Armellini
Source: Agencies
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