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Discover a selection of top forums members rasengan on the internet. Come to share your passion on forums members rasengan and meet other fans of members rasengan. Then, why don't you create your own forum of members rasengan ?
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Venice underwater!!
Design ID: 15012281
Noemí Carrau Gual, born in Barcelona, is a freelance illustrator and graphic art designer who lives and works in Venice, Italy. If you are interested in an individual created t-shirt design, just contact the artist at email@example.com
Drawings and Book Illustrations
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Suits any occasion: on a yacht, in the office or on a first date: This polo shirt cuts a very feminine figure, and it's a stylish companion to spread a breeze of Mediterranean atmosphere.
still to fill

subset: commoncrawl


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Entry Package to Ridiculous Obstacle Challenge 5K
Charlotte Motor Speedway • Concord, NC
Saturday, June 28
What you get
- One 5K Race Entry
- Includes Upgraded High-Performance ROC Race Technical T-Shirt
- Access to Post-Race Experience
- Following Purchase, Please Register Your Voucher Online
The ROC Race combines a 5K course with crazy game show themes from favorites like Wipeout, American Gladiators, Double Dare, and MXC. It features larger-than-life obstacles like the infamous Wrecking Ball, a four-story-tall inflatable water slide, and a 100-foot-long moon bounce. This untimed challenge welcomes all athletic abilities -- just show up at Charlotte Motor Speedway on Saturday, June 28 ready to have fun.
Choose from the following offers:
$64 ($101 value)* for a Wave 1, Wave 2, or Wave 3 entry package, including:
• Entry for one
• Upgraded high-performance ROC race technical T-shirt
• Race bib
• Bag check
• Access to post-race experience
• Insurance fee
*Price will increase closer to event date.
ROC Race 2014 Official Video from ROC Race on Vimeo.
Obstacles Include
Four-story-tall inflatable water slide
Wrecking Ball
100-foot-long moon bounce
Belly Flop Drop
Tarzan Swings
The Sweeper
Get It Up And Over Wall
...and more!
Fine printONLINE REGISTRATION REQUIRED BY: June 27th • REFUND POLICY: This event is nonrefundable. No full or partial refunds are given to customers who miss an event. In the event of a cancellation, your voucher will be fully refunded • Each voucher is good for 1 person • Includes ROC race processing fee and insurance fee • Must be 13+ • Wave 1: 7:30-10:30 a.m.; Wave 2: 11 a.m.-1:30 p.m.; Wave 3: 2-4:30 p.m.; running times every 30 minutes within each wave • Start times within waves are assigned on a first-come, first-serve basis; specific start times are not guaranteed and subject to change • The deal is valid only for tickets on the date[s] of the event as listed and may not be exchanged or redeemed for any other dates • Entire value must be used in a single visit
Other conditions apply
Except where noted in the fine print:
• Cannot be combined with any other offer or promotion
• Tax and gratuity are not included
• Merchant is responsible for the quality of the products or services provided to you at redemption
• LivingSocial Terms and Conditions - https://m.livingsocial.com/terms
Entry Package to Ridiculous Obstacle Challenge 5K
times for
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Findlay Liquor Stores
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Seems like we hit a network glitch.


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Foursquare © 2016 Lovingly made in NYC & SF
Café · €
Hommelstraat 66
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This item is currently
HN-TGP053 Sport Rack
SportRack Folding Hitch Basket #A30850Item # HN-TGP053
Roll over to zoom
Click for full screen
- Made to fit in 2 in. receiver hitch
- Heavy-duty all steel tubular construction
- Dimensions: 60L x 20W x 6H inches
Full Description
Guarantee & Returns
Sport Rack
SportRack Folding Hitch Basket #A30850
About ThuleEstablished in Sweden in 1942, Thule is a premium brand used globally for a wide assortment of products with a focus on making it easier to bring equipment with you when using a car. The company continually designs innovative roof racks, bike and water sport carriers, roof boxes, and more. Beyond that, Thule also develops accessories for recreational vehicles, trailers for active life – like horses, boats, and more -- snow chains, and luggage.


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|By Marketwired .
Article Rating:
|July 6, 2014 10:58 PM EDT
SEOUL, SOUTH KOREA -- (Marketwired) -- 07/06/14 -- JTBC-TV announced today 34 CEOs as '2014 The Most Powerful Business Leaders in Korea.'
Hosted by JTBC-TV and sponsored by Joongangilbo, Ministry of Science, ICT and Future Planning, and Ministry of Trade, Industry & Energy, '2014 The Most Powerful Business Leaders in Korea' recognizes the opinion leaders of Korean economy.
JTBC-TV also hosted the award ceremony on June 15th at Seoul Millennium Hilton Hotel attended by the award winners and the industry experts.
The following is the list of award winners:
- Cheol-Woo, Lee (CEO / DAESUNG ELECTRIC Co., Ltd.)
- Do-Bong, Park (Chairman / Dongyang Gangchul Co., Ltd.)
- Ki-Seok, Kim (CEO / Romanson Co.,Ltd.)
- Hyo-Sub, Lim (Chairman / Bohae Co.,Ltd.)
- Tae-Sun, Kang (Chairman / BLACKYAK Co.,Ltd.)
- Myung-Jun, Kim (CEO / Woory Industrial Co.,Ltd.)
- Young-Rok, Lim (Chairman / KB Financial Group.)
- Won-Suk, Oh (Chairman / KOREA FUEL - TECH CORPORATION.)
- Yong-Baek, Lee (CEO / HANSAE Co., Ltd.)
- Doo-Hee, Lee (President / KOREA UNIVERSITY BUSINESS SCHOOL.)
- Woo-Kyung, Kim (President & CEO / KOREA UNIVERSITY MEDICAL CENTER.)
- Hee-Ok, Kim (President / DONGGUK UNIVERSITY.)
- Kwang-Woong, Kim (President / MYONGJI COLLEGE.)
- Soon-Ki, Hong (Representative Lawyers / HanJoong Law Firm.)
- Sung-Gyun, Shin (President / Open Cyber University.)
- Byoung-Sik, Kim (President / CHODANG UNIVERSITY.)
- Sang-Hun, Han (Chairman / KAMICO(Korea Agricultural Machinery Industry Cooperative).)
- Young-Hak, Kim (President / Korea Trade Insurance Corporation.)
- Byong-Ho, Tchoe (President / Korea Institute for Health and Social Affairs.)
- Jong-In, Lee (Chairman / Korea Radioactive Waste Agency.)
- Hong-Ki, Lee (Chairman / Goid Line Group.)
- Young-Bae, Kim (Chairman / NAMDO. IC.)
- Dong-Gi, Kim (CEO / Nuri Development Company.)
- Beom-Jin, Lee (CEO / DukSan Corporation.)
- Kil-Tae, Kim (CEO / CERAGEMLOHAS.)
- Hyun-Keol, Kim(COO / SORIBADA INC.)
- Tae-Ok, Kim (Chairman / SEEHO VISION GROUP.)
- Min-Sun, Oh (CEO / STC GROUP Co.,Ltd.)
- Dong-Hwi, Kim (CEO / Yeowon Media.)
- Byung-Hoon Bill Lee (CEO / UNIVERA.)
- Joong-Myung, Cho (President & CEO / CrystalGenomics, Inc.)
- Seop, Choi (Chairman / Tae Kyoung Group.)
- Ki-Su, Han (CEO / PHILOPTICS CO., LTD.)
Dong Youn Kim
[email protected]
We've worked with dozens of early adopters across numerous industries and will debunk common misperceptions, which starts with understanding that many of the connected products we'll use over the next 5 years are already products, they're just not yet connected. With an IoT product, time-in-market provides much more essential feedback than ever before. Innovation comes from what you do with the data that the connected product provides in order to enhance the customer experience and optimize busi...
May. 5, 2016 06:00 AM EDT Reads: 1,340
In his session at 18th Cloud Expo, Sagi Brody, Chief Technology Officer at Webair Internet Development Inc., will focus on real world deployments of DDoS mitigation strategies in every layer of the network. He will give an overview of methods to prevent these attacks and best practices on how to provide protection in complex cloud platforms. He will also outline what we have found in our experience managing and running thousands of Linux and Unix managed service platforms and what specifically c...
May. 5, 2016 03:00 AM EDT Reads: 1,337
In his session at @ThingsExpo, Chris Klein, CEO and Co-founder of Rachio, will discuss next generation communities that are using IoT to create more sustainable, intelligent communities. One example is Sterling Ranch, a 10,000 home development that – with the help of Siemens – will integrate IoT technology into the community to provide residents with energy and water savings as well as intelligent security. Everything from stop lights to sprinkler systems to building infrastructures will run ef...
May. 5, 2016 02:00 AM EDT Reads: 1,293
Redis is not only the fastest database, but it has become the most popular among the new wave of applications running in containers. Redis speeds up just about every data interaction between your users or operational systems. In his session at 18th Cloud Expo, Dave Nielsen, Developer Relations at Redis Labs, will shares the functions and data structures used to solve everyday use cases that are driving Redis' popularity.
May. 5, 2016 01:45 AM EDT Reads: 1,238
Many private cloud projects were built to deliver self-service access to development and test resources. While those clouds delivered faster access to resources, they lacked visibility, control and security needed for production deployments. In their session at 18th Cloud Expo, Steve Anderson, Product Manager at BMC Software, and Rick Lefort, Principal Technical Marketing Consultant at BMC Software, will discuss how a cloud designed for production operations not only helps accelerate developer...
May. 5, 2016 01:00 AM EDT Reads: 1,318
Manufacturers are embracing the Industrial Internet the same way consumers are leveraging Fitbits – to improve overall health and wellness. Both can provide consistent measurement, visibility, and suggest performance improvements customized to help reach goals. Fitbit users can view real-time data and make adjustments to increase their activity. In his session at @ThingsExpo, Mark Bernardo Professional Services Leader, Americas, at GE Digital, will discuss how leveraging the Industrial Interne...
May. 5, 2016 12:45 AM EDT Reads: 1,382
The increasing popularity of the Internet of Things necessitates that our physical and cognitive relationship with wearable technology will change rapidly in the near future. This advent means logging has become a thing of the past. Before, it was on us to track our own data, but now that data is automatically available. What does this mean for mHealth and the "connected" body? In her session at @ThingsExpo, Lisa Calkins, CEO and co-founder of Amadeus Consulting, will discuss the impact of wea...
May. 5, 2016 12:00 AM EDT Reads: 1,206
Whether your IoT service is connecting cars, homes, appliances, wearable, cameras or other devices, one question hangs in the balance – how do you actually make money from this service? The ability to turn your IoT service into profit requires the ability to create a monetization strategy that is flexible, scalable and working for you in real-time. It must be a transparent, smoothly implemented strategy that all stakeholders – from customers to the board – will be able to understand and comprehe...
May. 4, 2016 11:45 PM EDT Reads: 1,269
Increasing IoT connectivity is forcing enterprises to find elegant solutions to organize and visualize all incoming data from these connected devices with re-configurable dashboard widgets to effectively allow rapid decision-making for everything from immediate actions in tactical situations to strategic analysis and reporting. In his session at 18th Cloud Expo, Shikhir Singh, Senior Developer Relations Manager at Sencha, will discuss how to create HTML5 dashboards that interact with IoT devic...
May. 4, 2016 09:00 PM EDT Reads: 1,431
Struggling to keep up with increasing application demand? Learn how Platform as a Service (PaaS) can streamline application development processes and make resource management easy.
May. 4, 2016 09:00 PM EDT Reads: 2,245
Up until last year, enterprises that were looking into cloud services usually undertook a long-term pilot with one of the large cloud providers, running test and dev workloads in the cloud. With cloud's transition to mainstream adoption in 2015, and with enterprises migrating more and more workloads into the cloud and in between public and private environments, the single-provider approach must be revisited. In his session at 18th Cloud Expo, Yoav Mor, multi-cloud solution evangelist at Cloudy...
May. 4, 2016 07:30 PM EDT Reads: 1,711
Artificial Intelligence has the potential to massively disrupt IoT. In his session at 18th Cloud Expo, AJ Abdallat, CEO of Beyond AI, will discuss what the five main drivers are in Artificial Intelligence that could shape the future of the Internet of Things. AJ Abdallat is CEO of Beyond AI. He has over 20 years of management experience in the fields of artificial intelligence, sensors, instruments, devices and software for telecommunications, life sciences, environmental monitoring, process...
May. 4, 2016 05:30 PM EDT Reads: 1,423
The demand for organizations to expand their infrastructure to multiple IT environments like the cloud, on-premise, mobile, bring your own device (BYOD) and the Internet of Things (IoT) continues to grow. As this hybrid infrastructure increases, the challenge to monitor the security of these systems increases in volume and complexity. In his session at 18th Cloud Expo, Stephen Coty, Chief Security Evangelist at Alert Logic, will show how properly configured and managed security architecture can...
May. 4, 2016 05:15 PM EDT Reads: 474
Unless you don't use the internet, don't live in California, or haven't been paying attention to the recent news… you should be aware that self-driving cars are on their way to becoming a reality. I have seen them – they are real. If you believe in the future reality of self-driving cars, then continue reading on. If you don't believe in the future possibilities, then I am not sure what to do to convince you other than discuss the very real changes that will roll out with the consumer producti...
May. 4, 2016 04:30 PM EDT Reads: 835
A critical component of any IoT project is the back-end systems that capture data from remote IoT devices and structure it in a way to answer useful questions. Traditional data warehouse and analytical systems are mature technologies that can be used to handle large data sets, but they are not well suited to many IoT-scale products and the need for real-time insights. At Fuze, we have developed a backend platform as part of our mobility-oriented cloud service that uses Big Data-based approache...
May. 4, 2016 03:30 PM EDT Reads: 711


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Relevant offers
Jaimee Leader's rise as one of the country's future triathlon stars has continued during a stellar season this summer.
The Palmerston North teenager is midway through her first season competing in the Contact Tri Series and is getting some good results at only 15 years old.
Leader competed in her first Tri Series event at Rotorua last month and kicked off the season in perfect style as she won the sprint distance race and finished four minutes ahead of world under-19 champion Steffie Holcroft.
She competed again at the next round at Whangamata at the start of January where she was third in the sprint distance (750m swim, 20km cycle and 5km run).
Then two weeks ago, she competed at the next round at Christchurch where she finished seventh.
"It's an exciting sport travelling around," Leader said. "The thrill and the challenge of racing. I wouldn't know what to do if I wasn't doing it."
At the man-made Pegasus course near Christchurch, she got to race alongside some of New Zealand's top triathletes such as Andrea Hewitt and Kate McIlroy, who the youngster was keeping time with after the first leg of the race.
"I didn't get to see them much. I came out with them in the swim," Leader said. "I was really pleased with that but, then they left me."
She said it was a good experience to be racing alongside the stars who are "on a different level" to her now, but "hopefully that's where I'm headed".
The Palmerston North Girls' High School student has been a protege of former Olympian Samantha Warriner, who has done a great job mentoring Leader, making sure she is on the right track with her career, especially because she is so young.
A lot of the girls Leader competes against are older but she enjoys the challenge it presents.
"I reckon it is a high level of competition. I raced them last year in the schools nationals and came third when they were a year older than me.
"It's great to be able to compare yourself to older people and see how you're going."
Her next big goal is the national sprint distance championships at Kinloch next month and she is eyeing the schools nationals at Christchurch at the end of March.
She also wants to get in the Triathlon New Zealand youth development team after Warriner thought she was too young last year.
Leader has plenty of time to develop. She is only starting year 11 at Girls' High this year, where she won the junior sportsperson of the year award last year.
Through the help of Warriner, she has picked up a sponsorship deal with Asics which should make her life easier as an athlete.
A strict trainer, Leader doesn't like rest days and even on her days off she wants to be training, which she does three times a day.
- Manawatu Standard
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How will the Hurricanes do in 2015?Related story: Supporting players light up Hurricanes bright start to Super Rugby season


text:
(916) 331-0868
4754 Auburn Boulevard
B & M Automotive & Smog Center telephone number is (916) 331-0868.
Telefax: No fax number available
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Biz owner? Moderate reviews or edit listing.
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Search entire category for Car Financing & Loans
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Helpful Tip for: Car Financing & Loans
Car Financing and loans, in Sacramento, would refer to money granted on interest for a term period by a financial institution to an individual for purchasing car or an automobile. Rate of interest, down payment, terms of the loan, rebate, etc, are decided normally after taking an individual's credit history into consideration.
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Governor Cuomo Announces First Solar Schools Project At The New York Institute For Special Education In The Bronx
Governor Cuomo's K-Solar Program Increases Use of Renewable Energy in Schools (New York, NY) Governor Andrew M. Cuomo today announced the New York Institute for Special Education in the Bronx will be the site of the state's first solar schools project and will have solar panel arrays installed thanks to a power purchase agreement with SolarCity. This public-private partnership is..
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text:
SmartScore 99
SmartScore 99
SmartScore 86
SmartScore 92
Here's the question you clicked on:
Help please If 2x = a + b + c show (x-a)^2 +(x-b)^2 + (x-c)^2+x^2 = a^2 +b^2+c^2.
IF 2x=a+b+c Show that \[(x-a)^{2}+(x-b)^{2}+(x-c)^{2} +x ^{2}=a ^{2}+b ^{2}+c ^{2}\]
it have no idea how to start!!!
You can use the Intermediate Value Theorem. Note that F is a polynomial and hence is differentiable everywhere (differentiable ==> continuous). I'll assume a < b---order doesn't really matter, but I do want a to be different from b. Consider the interval [a, b]. Note that f(a) = a, and f(b) = b. The number (a + b)/2 is between a and b (exactly half way in between!). The IVT says that if f takes on the values a and b it has to take on every value between them. It follows immediately that there exists c in (a, b) such that f(c) = (a + b)/2.
Does that help?
im lost :P
Well that is the only way i can explain it
whatever you just typed is very confusing as my question is clearly not a polynomial...
ok well sorry, bye..!
\[(x-a)^2+(x-b)^2+(x-c)^2+x^2=x^2-2ax+a^2+x^2-2bx+b^2+x^2-2xc+c^2+x^2\\=4x^2+a^2+b^2+c^2-2ax-2bx-2cx\\=(2x)^2+a^2+b^2+c^2-2x(a+b+c)\\=(a+b+c)^2+a^2+b^2+c^2-(a+b+c)(a+b+c)\\=(a+b+c)^2+a^2+b^2+c^2-(a+b+c)^2\\=a^2+b^2+c^2 \]
whoops, the \(+x^2\) wouldn't show.
thank you


text:
|By Business Wire
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|April 10, 2014 07:00 AM EDT
As the consumer, industrial and automotive infotainment markets evolve rapidly to meet the demands of increasingly discerning end-users, systems designers need processors with the performance to run rich user interfaces without sacrificing real-time responsiveness or power efficiency. To achieve this, systems designers often must choose between multi-chip solutions, which increase cost, board space, and system complexity; or adopting virtualization on a multicore processor, which can negatively impact real-time performance and system power.
To address this challenge, Freescale Semiconductor (NYSE:FSL) introduces the industry's first applications processor to integrate an ARM Cortex-A9 processor and an ARM Cortex-M4 processor in a single chip design. This design enables enhanced flexibility, performance and low-power functionality for the company's flagship i.MX 6 applications processor family.
"Freescale has leveraged its experience and deep understanding of microcontrollers, microprocessors and heterogeneous SoC design to deliver yet another industry first," said Rajeev Kumar, worldwide director of marketing and business development for Freescale's MCU business. "For our customers, this innovative device provides the most comprehensive solution available in a single chip for applications requiring rich user interfaces, real-time responsiveness and optimized low power operation."
Freescale's i.MX 6 series of applications processors is growing quickly, particularly in the automotive space, where shipments grew more than 50 percent from 2012 to 2013. According to analyst firm Strategy Analytics, Freescale ranks #2 in automotive market share for applications processors.
Integrating a Cortex-M4 processor alongside a Cortex-A class system provides customers with a cost-effective single-chip solution that can run a sophisticated operating system and provide real-time responsiveness to help build the next generation of connected, highly graphical and system-aware devices. Freescale's innovative heterogeneous applications processor design provides additional low power modes to significantly reduce standby power consumption, allows for smaller form factor design, and executes fast, real-time responsiveness to system inputs.
To support applications which simultaneously require real-time task processing and compute-intensive capabilities, the SoC incorporates four independently controlled resource domains for optimal flexibility when partitioning system resources such as memory and peripherals. As a result, peripheral and memory access requests are hardware-verified to provide secure isolation and prevent tainting of system resources.
Additional features of the newest i.MX 6 series processor include:
- Dual-port gigabit Ethernet audio video bridging (AVB) for quality-of-service in automotive and other applications with enhanced traffic shaping and packet prioritization.
- Cost-effective 2D and 3D graphics processing unit (GPU) for enhanced HMI development.
- Flexible boot options, including support for quad SPI and raw NAND, and a memory controller that interfaces to both DDR3 and low power DDR2.
- Smart integration of standard system interfaces, including multiple interface options for UI and wireless connectivity to provide system design flexibility and low overall BOM.
Alpha samples of this expanded i.MX 6 processor are available now, with full production expected in Q4 2014. The design is available with a comprehensive set of development tools and software support including Android and Linux operating systems for the Cortex-A9 processor, the MQX™ OS for the Cortex-M4 processor and the broad ARM community of support. Also planned for availability in Q4 is the expanded i.MX 6 series SABRE board. The newest i.MX device joins an already-broad portfolio of i.MX 6 series products shipping today, offering multiple processing and integration options for maximum flexibility and scalability.
About Freescale Semiconductor
Freescale Semiconductor is a global leader in embedded processing solutions, providing industry leading products that are advancing the automotive, consumer, industrial and networking markets. From microprocessors and microcontrollers to sensors, analog integrated circuits and connectivity - our technologies are the foundation for the innovations that make our world greener, safer, healthier and more connected. Some of our key applications and end-markets include automotive safety, hybrid and all-electric vehicles, next generation wireless infrastructure, smart energy management, portable medical devices, consumer appliances and smart mobile devices. The company is based in Austin, Texas, and has design, research and development, manufacturing and sales operations around the world. http://www.freescale.com.
Freescale and the Freescale logo are trademarks of Freescale Semiconductor, Inc., Reg. U.S. Pat. & Tm. Off. All product or service names are the property of their respective owners. ARM and Cortex are trademarks or registered trademarks of ARM Ltd. or its subsidiaries in the EU and/or elsewhere. All rights reserved. All other product or service names are the property of their respective owners. © 2014 Freescale Semiconductor, Inc.
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text: Watch video Krall, Costello light up Vancouver Add to ... The Globe and Mail Published Wednesday, Dec. 09, 2009 3:18PM EST Last updated Wednesday, Dec. 09, 2009 3:19PM EST A Christmas tree in downtown Vancouver is now shining a little brighter, with some high-profile help. Musical couple Elvis Costello and Diana Krall took part in a lighting ceremony Tuesday, hitting the button to illuminate a tree outside the city's art gallery. Watch More Video: Yen soars as Bank of Japan holds steady Bryant's Last Game: This is Kind of Crazy to Me Video: Talking Management: The downsides of power A juror explains her rationale on the Hulk Hogan sex tape ruling Multiple deaths in Brussels as blasts hit airport and metro How Gal Gadot brought Wonder Woman to life in 'Batman v Superman' Trump supporters clash with protesters Cleveland Vancouver rugby sevens event to help promote game in Canada Toronto at higher overheating risk than Vancouver: CMHC Corus Entertainment takeover of Shaw Media approved by investors Junk bonds surge V-shaped start to 7-year bull market was rare: Levine Happy Birthday to bull market for U.S. stocks Surgeons Perform First Uterus Transplant in US How Sun Life executives encourage innovation Oil hits 2016 high while confidence sags in Alberta Michelle Obama honours International Women's Day CTV Vancouver: Sentencing for Batalia's killer Investing in small cap Canadian tech TransCanada blames $175M charge on Alberta's new climate laws Comments AA


text:
Police in Carbon County have arrested a man accused of being a peeping Tom in a Wal-Mart restroom.
Police say Anthony Mistretta, 48, of Nesquehoning admitted to using a mirror to view three people in the men's bathroom at the Wal-Mart on Route 443 in Mahoning Township Sunday.
Police say they tracked down Mistretta after seeing him on a store security video.
He has been charged with three counts of invasion of privacy.
Walmart restroom peeping Tom in Carbon County
Published On: Apr 29 2013 08:00:00 PM EDT Updated On: Apr 30 2013 06:39:27 AM EDT
Police in Carbon County have arrested a man accused of being a peeping Tom in a Wal-Mart restroom.
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text:
|Publication number
|Publication type
|Application number
|PCT number
|Publication date
|May 2, 2006
|Filing date
|Nov 11, 2002
|Priority date
|Nov 14, 2001
|Fee status
|Also published as
|Publication number
|Sune Svanberg, Stefan Andersson-Engels, Katarina Svanberg
|Original Assignee
|Spectracure Ab
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (10), Referenced by (20), Classifications (17), Legal Events (5)
|External Links: USPTO, USPTO Assignment, Espacenet
The invention relates to a system and a method for interstitial photodynamic and photothermal tumor therapy and diagnosis of a tumor at a tumor site in a body, wherein radiation is conducted to the site for said therapy and diagnosis. The system comprises a distributor of radiation from at least one therapeutic radiation source and a diagnostic radiation source to said tumor, and from the tumor to at least one radiation sensor, respectively.
Within the field of medical therapy of tumor diseases, a plurality of treatment modalities has been developed for the treatment of malignant tumor diseases, e.g. a tumefaction. Operation, cytostatics treatment, treatment with ionising radiation (gamma or particle radiation), isotope therapy, and brachy therapy employing radioactive needles are examples of common treatment modalities. In spite of great progress within therapy, the tumor diseases continue to account for much human suffering, and are responsible for a high percentage of deaths in Western countries. A relatively new treatment modality, photodynamic therapy, commonly abbreviated PDT, provides an interesting complement or alternative in the treatment field. A tumorseeking agent, normally referred to as a sensitizer, is administered to the body intravenously, orally or topically. It accumulates in malignant tumors to a higher extent than in the surrounding healthy tissue. The tumor area is then irradiated with nonthermal red light, normally from a laser, leading to excitation of the sensitizer to a more energetic state. Through energy transfer from the activated sensitizer to the oxygen molecules of the tissue, the oxygen is transferred from its normal triplet state to the excited singlet state. Singlet oxygen is known to be particularly toxic to tissue; cells are eradicated and the tissue goes in necrosis. Because of the localization of the sensitizer to tumor cells a unique selectivity is obtained, where surrounding healthy tissue is spared. The initial clinical experience, using in particular haematoporphyrin derivative (HPD) and delta amino levulinic acid (ALA) are good.
Sensitizers also exhibit a further useful property; to yield a characteristic red fluorescence signal when the substance is excited with violet or ultraviolet radiation. This signal clearly appears in contrast to the autofluorescence of the tissue and can be used to localize tumors and for quantifying the size of the uptake of the sensitizer in the tissue.
The limited penetration in the tissue of the activating red radiation is a big drawback of PDT. The result is that only tumors up to about 5 mm thickness can be treated by surface irradiation. In order to treat thicker and deep-lying tumors, interstitial PDT (IPDT) can be utilized. Here, light-conducting optical fibers are brought into the tumor using, e.g. a syringe needle, in the lumen of which a fiber has been placed.
In order to achieve an efficient treatment, several fibers have been used to ascertain that all tumor cells are subjected to a sufficient dose of light so that the toxic singlet state is obtained. It has been shown to be achievable to perform dose calculations of the absorptive and scattering properties of the tissue. E.g., in the Swedish patent SE 503 408 an IPDT system is described, where six fibers are used for treatment as well as for measurement of the light flux which reaches a given fiber in the penetration through the tissue from the other fibers. In this way an improved calculation of the correct light dose can be achieved for all parts of the tumor.
In the equipment described in SE 503 408 the light from a single laser is divided up in six different parts using a beamsplitter system comprising a large number of components. The light is then focused into each of the six individual treatment fibers. One fiber is used as a transmitter while the other fibers are used as receivers of radiation penetrating the tissue. For light measurement light detectors are swung into the beam path which thus is blocked, and the weak light, which originates from the fibers that collected the light which is administered to the tissue, is measured.
However, such open beam paths result in a strongly lossy beamsplitting and the resulting losses of light drastically impair the light distribution as well as the light measurement. Furthermore, such a system must often be adjusted optically, which is also an important consideration in connection with clinical treatments.
In one embodiment, the invention comprises a system for interactive interstitial photodynamic or photothermal tumor therapy and tumor diagnosis, comprising at least one therapeutic radiation source and at least one diagnostic radiation source, at least one diagnostic radiation sensor, and at least two primary radiation conductors which at their distal ends are interstitially arranged in a tumor site, wherein the primary radiation conductors in use are employed as a transmitter for diagnostic radiation from said diagnostic radiation source for diagnosis of a tumor at said tumor site, or for therapeutic radiation from said therapeutic radiation source for therapy of the tumor, respectively or as a receiver for conduction of radiation from the tumor site for diagnosis of the tumor at the tumor site, and a distributor for distribution of radiation from the diagnostic and therapeutic radiation source to the tumor site, and from the tumor site to at least one diagnostic radiation sensor. In preferred embodiments, the distributor comprises a plurality of primary radiation conductors arranged for conducting radiation to and from the tumor site, a plurality of secondary radiation conductors arranged for delivering radiation from the diagnostic or therapeutic radiation source or conduction of radiation to the diagnostic radiation sensor, two flat discs abutting against each other, wherein a first of said discs is fixed and the second of said discs is turnable relatively to the other disc, and wherein each disc has holes arranged on a circular line. The proximal ends of the primary radiation conductors are fixed in the holes of the first disc and distal ends of the secondary radiation conductors are fixed in the holes of the second disc, whereby the primary and the secondary radiation conductors by rotation of the two discs relative another are connectable to each other in different constellations.
In another embodiment, a method for interactive interstitial photodynamic or photothermal tumor therapy and diagnosis. The method preferably comprises inserting at least two primary radiation conductors at distal ends thereof interstitially into a tumor, activating a diagnostic radiation source and transmitting diagnostic radiation through one of said primary radiation conductors to the distal ends thereof, transmitting the diagnostic radiation through tissue at said tumor site to distal ends of the remaining primary radiation conductors, collecting and evaluating diagnostic information from radiation received from said tumor, automatically switching between tumor therapy and tumor diagnostics, and controlling the tumor therapy by regulating a therapeutical radiation intensity depending on said diagnostic information.
In order to more closely explain the invention a number of embodiments of the invention will be described in the following with reference to the figures, wherein
A preferred embodiment of the distributor of the system according to the invention is now described with reference to
Evenly distributed holes 5 lying on a circle are arranged in both discs (
By employing discs drilled together, radiation conductors can be fixed in said discs, wherein an extra, thinner disc then can be turned slightly, preferably springloaded, so that all light conductors are simultaneously pinched in their positions without the need for any glue or other fixation means. Alternatively, the diameter of the holes is made larger than the diameter of the light conductors, wherein the holes can be dressed with an appropriate piece of tubing, or the ends of the light conductors can be supplied with a fitted hose. Alternatively, the ends of the light conductors can be flared or flanged into the holes.
Preferably the light conductors are optical fibers, wherein different types of hoses or flexible tubes containing a light-conducting material are included. The light conductors should have such a length and be arranged in such a way that the turnable disc 4 can be turned without problems a full turn (360 degrees). The direction of movement can be reversed to avoid the light conductors forming a spiral.
According to the invention a plurality of primary light conductors 6 in a system are arranged in the fixed disc 3 for conduction of radiation to and from a reaction site 8. By a reaction site we in the present context mean a site where photodynamically active compounds will react in a tumor when subject to therapy. E.g., by being forwarded through the lumen of injection needles which are placed in the tumor, these primary radiation conductors 6 are then fixed in the reaction site 8. Then the primary radiation conductors are moved forward to arrive outside the distal end of the needle. The same light conductor 6 is used all the time for integrated diagnostics and dosimetry, to avoid that the patient be subjected to multiple pricks.
The holes 5 in the fixed disc 3 as well as in the turnable disc 4 are arranged on a circular line, wherein the circle radius on one disc equals the circle radius on the other disc. The holes on one disc are equally distributed along the circle line with an angular separation of
v1=(360/n1) degrees, where n1 equals the number of holes, and the holes of the other disc are equally distributed along the circle line with an angular separation v2 equalling (360/n2) degrees. The proximal ends of the primary radiation conductors 6 are fixed in the holes of the fixed disc 3, and distal ends of the secondary radiation conductors 7 are fixed in the holes of the turnable disc 4. In order to make the holes, and thereby the primary and secondary radiation conductors in both discs connectable to each other in different constellations by turning of the turnable disc 4, n2 is selected to be a multiple of n1, in such a way that n2 is obtained as an integer larger or equal to 1. Suitably the number of holes in the fixed disc is chosen from two to more than six.
Preferably six holes are arranged in the fixed disc 3 and twelve holes are arranged in the turnable disc 4. With six primary radiation conductors 6 the angular separation will accordingly become 60 degrees in the fixed disc 3 and with twelve holes arranged in the turnable disc 4 the angular separation will become 30 degrees for the secondary radiation conductors 7.
In order to facilitate the comprehension of the invention the following description of a preferred embodiment of the distributor of the system according to the invention relates to six primary radiation conductors 6 arranged with their proximal ends in the fixed disc 3 for conduction of radiation to and from the reaction site 8 at the distal ends of the primary radiation conductors.
Thus, the turnable disc 4, as well as the fixed disc 3, have six holes 5 for corresponding six diagnostic secondary radiation conductors 7, and, in addition, six further holes for six therapeutic secondary radiation conductors 7. All these twelve radiation conductors 7 can release radiation to the reaction site 8 and receive radiation from said site. Thus, several spectra can be recorded and read out simultaneously.
By turning the turnable disc 4 the primary and the secondary radiation conductors become connectable to each other in different constellations. An exact positioning of the opposing radiation conductors in the distributor 1 is facilitated by arranging means for stopping the turnable disc 4 in predetermined angular positions. E.g., groves 10 can be arranged in the axis 2 for catching a springloaded ball 11 arranged in the turnable disc 4 (
In order to allow a fast and efficient switching between a diagnostic mode and a therapeutic mode, every other of the secondary light conductors of the distributor 1 according to the invention, are divided into a diagnostics and into a therapeutic series. Both series of holes are arranged on the same circle, but displaced by 30 degrees with regard to each other. A specific therapeutic light conductor 7 a′ in the diagnostic series of every other secondary light conductor is arranged for emitting radiation from at least one diagnostic radiation source 9 a. The other, non specific diagnostic radiation conductors 7 a in the diagnostic series of secondary radiation conductors are arranged for conduction of radiation to at least one diagnostic radiation sensor 12. The therapeutic series of every other secondary radiation conductor 7 b is for therapeutical purposes arranged to emit radiation to the reaction site 8 from at least one therapeutic radiation source 9 b.
In the preferred embodiment of the invention, the primary and secondary radiation conductors are optical fibers, which in the distributor 1 shown in
With reference to
By turning the turnable disc 4 by 30 degrees the primary fibers 6 which at their distal ends, respectively, are optically coupled to the tissue of the patient can be employed for therapy as well as diagnostics and measurements. One out of every diagnostic secondary radiation conductor 7 is in the diagnostic mode connected to different radiation sources for diagnostics, while the other five diagnostic radiation conductors receive signals, which are related to the interaction of these diagnostic radiation sources with the tissue.
Since intensity as well as spectral resolution is of interest, the distal ends of these five diagnostic radiation conductors are arranged in a slit-like arrangement so that they overlap the entrance slit and/or constitute the entrance slit of the radiation sensor 12, which is a compact spectrometer and is supplied with a two-dimensional detector array. The recording range of the spectrometer is preferably within the range 400 to 900 nm. Each of the diagnostic radiation conductors 7 a can of course be connected to an individual radiation detector 12 in the form of a spectrometer or another type of detector, e.g. a compact integrated spectrometer.
With reference to
More specifically the diagnostic radiation conductor 7 a′ is proximally arranged in a single hole on the second fixed disc 13. Further diagnostic light conductors 17 are arranged on a circle in said second turnable disc 14; in this case three diagnostic light conductors which at their proximal end, respectively, are connected to different radiation sources 9 a, and which each are connectable to the diagnostic radiation conductor 7 a′ and further on to a primary radiation conductor 6′ comprised in the different primary radiation conductors 6 (See
Preferably the diagnostic radiation source 9 a is a laser of the same wavelength as the one utilized for the laser irradiation for photodynamic tumor therapy, but of substantially lower output power. Suitable filters can be arranged on the second turnable disc 14, to be turned into the light path of the diagnostic radiation sensor 12 in order to secure that the correct dynamic range is utilized for all measurement tasks.
Certain of the diagnostic radiation sources 9 a are utilized in order to study how radiation (light) of the corresponding wavelength is penetrating through the tissue of the tumor. When light from a diagnostic radiation source 9 a is transmitted through the particular diagnostic radiation conductors 17, 7 a′, 6′ via the discs 14, 13, 4, 3, respectively, into the tissue 8, one of the primary radiation conductors 6, which is the radiation conductor 6′ opposing the diagnostic radiation conductor 7 a′ in the distributor 1, will function as a transmitter into the tumor 8, and the other five primary radiation conductors 6 having their distal ends arranged in the tumor 8 will act as receivers and collect the diffuse flux of light reaching them. The light collected is again conducted via the discs 3, 4, and diagnostic radiation conductors 7 a to the radiation sensor 12 and five different light intensities can be recorded on the detector array.
When the turnable disc 4 is turned by 60 degrees, the next primary radiation conductor 6 to the patient will get the role as transmitter, and the five others become the receivers for a new light distribution. After four further turns of the turnable disc 4, each by 60 degrees to the following primary radiation conductor 6 in the patient, light flux data for all remaining combinations of transmitters/receivers have been recorded. Thus, in total 6*5=30 measurement values are obtained and can be used as input data for a tomographic modelling of the optical dose build up in the different parts of the tumor during the course of the treatment.
As an alternative to a specific wavelength, radiation from a white light source can be coupled into the particular diagnostic light conductor 7 a′ and into the tissue from the distal end of primary radiation conductor 6′. From the distal end of primary radiation conductor 6′, on passage through the tissue to the distal end of the receiving light conductor 6 in the patient, the well-defined spectral distribution of the diagnostic radiation source 9 a will be modified by the tissue absorption. Then, oxygenated blood yields a different signature than non-oxygenated blood, allowing a tomographic determination of the oxygen distribution utilizing the thirty different spectral distributions which are read out, five spectra at a time in the six possible different constellations on rotation of the turnable disc 4 during a diagnostic investigation. Such a determination of the oxygenation in the tumor is important, since the PDT process requires access to oxygen in the tissue.
Finally, a light source for blue/violet or ultraviolet light, e.g. a laser, can be coupled to the particular radiation conductor 7 a′. Then fluorescence is induced in the tissue, and a sensitizer administered to the tissue displays a characteristic red fluorescence distribution in the red/near-infrared spectral region. The strength of the corresponding signal allows a quantification of the concentration of the sensitizer in the tissue.
Since the short wavelength light has a very low penetration into the tissue, the induced fluorescence must be measured locally at the tip of the distal end of the primary radiation conductor. For this task there is in this case for the corresponding radiation source 9 a at the proximal end of the particular diagnostic radiation conductor 17 a beamsplitter 18, which is preferably dichroitic, transmitting the exciting light but reflecting the red-shifted fluorescence light. This reflected light is focused into the proximal end of a conveying radiation conductor 19, the distal end of which is connected to the radiation sensor 12, which records the fluorescence light distribution. A suitable self-contained fluorosensor is described in Rev. Sci. Instr. 71, 3004 (2000).
By rotating the turnable disc 4, the fluorescence which is proportional to the concentration of the sensitizer, can be measured sequentially at the tips at the distal ends of the six primary radiation conductors. Since the sensitizer is bleached by the strong red treatment light, being particularly strong just around the tip of the primary radiation conductor 6′, it is essential to make this measurement before the start of the treatment.
If the tips of the primary radiation conductors 6 in addition are treated with a material, the fluorescence properties of which are temperature dependent, sharp fluorescence lines are obtained upon excitation, and the intensity of the lines and their relative strength depend on the temperature of the tip of the radiation conductor 6′. Examples of such materials are salts of the transition metals or the rare earth metals. Thus also the temperature can be measured at the six positions of the six radiation conductors, one at a time. The measured temperatures can be utilized to find out if blood coagulation with an associated light attenuation has occurred at the tip of the radiation conductor 6 and for studies regarding the utilization of possible synergy effects between PDT and thermal interaction. Since the lines obtained are sharp, they can be lifted off the more broad-banded fluorescence distribution from the tissue.
The concentration of the sensitizer can for certain substances be measured in an alternative way. Then the red light used for the light propagation studies is used to induce near-infrared fluorescence. This fluorescence penetrates through the tissue to the tips of the receiving primary radiation conductors 6, and are displayed simultaneously as spectra obtained in the radiation sensor 12. A tomographic calculation of the concentration distribution can be performed based on in total thirty measurement values.
After diagnostic measurements and calculations have been performed, the primary fibers 6 optically coupled to the tissue of the patients can be utilized for therapy by rotation of the turnable disc 4 by 30 degrees. Referring to
The therapeutical treatment can be interrupted and new diagnostic data can be processed in an interactive method till an optimal treatment has been reached. This method can include synergy between PDT and hyperthermia, where an increased temperature is reached at increased fluxes of laser radiation. The whole process is controlled using a computer, which does not only perform all the calculations but also is utilized for regulation.
|Cited Patent
|Filing date
|Publication date
|Nov 10, 1997
|Nov 23, 1999
|Richard Wolf Gmbh
|Device for endoscopic diagnosis and treatment of tissue
|Aug 25, 1998
|Apr 11, 2000
|Advanced Photodynamic Technologies, Inc.
|Spatial orientation and light sources and method of using same for medical diagnosis and photodynamic therapy
|Jul 29, 1997
|Oct 3, 2000
|Zeng; Haishan
|Apparatus and method to monitor photodynamic therapy (PDT)
|Jul 8, 1999
|Apr 3, 2001
|Light Sciences Corporation
|Combined imaging and PDT delivery system
|Oct 19, 1995
|Apr 10, 2001
|Matsushita Electric Industrial Co., Ltd.
|Medical laser apparatus and diagnostic/treatment apparatus using the medical laser apparatus
|Apr 13, 2001
|Aug 5, 2003
|Kelsey, Inc.
|Apparatus and method for delivering ablative laser energy and determining the volume of tumor mass destroyed
|Mar 15, 2002
|Feb 20, 2003
|Yoshiteru Ii
|Medical laser apparatus and diagnostic/treatment apparatus using the medical laser apparatus
|Mar 14, 1986
|Sep 24, 1986
|Massachusetts Institute Of Technology
|Catheter for laser angiosurgery
|Title not available
|Title not available
|Citing Patent
|Filing date
|Publication date
|May 23, 2008
|Jan 31, 2012
|University Of Rochester
|Automated placental measurement
|Jul 17, 2009
|Jan 15, 2013
|University Of Rochester
|Low-cost device for C-scan photoacoustic imaging
|Jul 14, 2010
|Nov 12, 2013
|Spectracure Ab
|System and method for pre-treatment planning of photodynamic light therapy
|Dec 12, 2012
|Oct 28, 2014
|University Of Rochester
|Low-cost device for C-scan acoustic wave imaging
|Aug 15, 2007
|Mar 24, 2015
|Spectracure Ab
|System and method for controlling and adjusting interstitial photodynamic light therapy parameters
|Jun 30, 2005
|Jun 2, 2015
|University Of Rochester
|Photodynamic therapy with spatially resolved dual spectroscopic monitoring
|Jan 15, 2004
|Jul 21, 2005
|Ceramoptec Industries, Inc.
|Multiple port photodynamic therapy irradiation system
|Oct 29, 2004
|May 4, 2006
|Kian Shin Lee
|Method and apparatus for regulating light administered at a patient treatment site
|May 3, 2006
|Dec 14, 2006
|John Tulip
|Switched photodynamic therapy apparatus and method
|Apr 6, 2007
|Dec 6, 2007
|University Of Rochester
|Side-firing linear optic array for interstitial optical therapy and monitoring using compact helical geometry
|Jun 28, 2007
|Feb 7, 2008
|John Tulip
|Switched photodynamic therapy apparatus and method
|Jun 30, 2005
|Feb 12, 2009
|University Of Rochester
|Photodynamic therapy with spatially resolved dual spectroscopic monitoring
|May 23, 2008
|Nov 26, 2009
|Placental Analytics, Llc.
|Automated placental measurement
|Oct 15, 2009
|Nov 25, 2010
|Dogra Vikram S
|Photoacoustic imaging using a versatile acoustic lens
|Jul 14, 2010
|Dec 30, 2010
|Spectracure Ab
|System and method for pre-treatment planning of photodynamic light therapy
|May 2, 2008
|Dec 30, 2010
|Cottrell William J
|Feedback-controlled method for delivering photodynamic therapy and related instrumentation
|Aug 15, 2007
|Feb 10, 2011
|Spectracure Ab
|System and method for controlling and adjusting interstitial photodynamic light therapy parameters
|Aug 15, 2007
|Mar 23, 2011
|Spectracure AB
|System for controlling and adjusting interstitial photodynamic light therapy parameters
|Aug 15, 2007
|Mar 21, 2012
|SpectraCure AB
|System for controlling and adjusting interstitial photodynamic light therapy parameters
|Dec 7, 2011
|Jun 14, 2012
|Spectracure Ab
|System and method for interstitial photodynamic light therapy in combination with photosensitizers
|U.S. Classification
|607/89, 607/88, 128/898
|International Classification
|Cooperative Classification
|European Classification
|Aug 17, 2004
Owner name: SPECTRACURE AB, SWEDEN
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:SVANBERG, SUNE;REEL/FRAME:015684/0534
Effective date: 20021115
Owner name: SUNE SVANBERG, SWEDEN
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:SVANBERG, KATARINA;ANDERSSON-ENGELS, STEFAN;REEL/FRAME:015684/0519
Effective date: 20021115
|Dec 7, 2009
|Maintenance fee reminder mailed
|Mar 4, 2010
|Surcharge for late payment
|Mar 4, 2010
|Fee payment
Year of fee payment: 4
|Oct 22, 2013
|Fee payment
Year of fee payment: 8


text:
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- Tickets >
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SOURCE: Jerusalem Post
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William Collins Donahue: Munich's Foiled History Lessons – An American PerspectiveRoundup: Talking About History
The writer is the chair of the Department of Germanic Languages & Literatures and a professor of German and Jewish Studies at Duke University.
My daughter and I recently toured Munich's beautiful Olympic Park, the site of the brutal 1972 massacre of young Israeli athletes by the Palestinian terror group Black September.
The day we visited was idyllic: skateboarders careened off steeply-banked slopes; children roller-skated and bicycled, while others walked their dogs, jogged or just took in the gorgeous day.
Nearby, swimmers splashed in the great swimming hall, the impressive glass and steel structure designed to maximize the brilliant sunshine on a day like this. Later, we partook of kaffee and kuchen – coffee and cake – at a rotating restaurant atop one of Germany's architectural wonders, a radio and TV tower built on pliable gravel that allows it to actually tilt in high winds, and in calmer weather simply offers the best view of the city.
In soaking this all in, not once was I, a scholar who has spent much of my career thinking and writing about contemporary Germany, reminded of the unspeakable attack.
As we near the 40th anniversary of the September 5, 1972 massacre of 11 Israeli athletes and coaches at the Munich Olympic Games, we are reminded not only of Germany's failure to protect its guest athletes, but also of its attempt to become a "good" democracy in the American mold...
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...I teach them strategies for studying for tests and for organizing schoolwork, belongings, and "life." I work with them on "meta" strategies, helping them to know themselves better and helping them come to determine which particular strategies work the best for them. I have years of experience w...
Lexington, MAView Tutor
...Aside from in-home private tutoring, I've tutored for the Boston University Upward Bound program for a few years, the MATCH charter school for one year, and the Nativity Preparatory School for one year. Before going back into tutoring in September of 2014, I had about 4 years of working in the c...
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...My goal is to get you on track, identify those stumbling blocks, and work through them. My goal is to get you comfortable and competent in the material so that the entire learning experience is rewarding in many ways. Longer term, that approach can open up many opportunities in the future, that may be hard to anticipate now.
Belmont, MAView Tutor
...I graduated with honors from Fairfield University with a math degree and education minor. I also hold a Master?s degree in math from Boston College. I was the recipient of the Teaching Excellence Award at BC and the Teaching Inclusion Award from BHS.
Lexington, MAView Tutor
...Excellent recommendations available on WyzAnt. Additional references are available upon request. "A mediocre teacher tells. A good teacher explains.
Andover, MAView Tutor


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Despite economic pressures posed by mounting international sanctions, the Iranian president sees more than a double increase in the defense budget and 8 percent economic growth for the next 12 months. 'Considering threats against Iran, it was necessary to increase the defense budget,' says an Iranian MP.
President Mahmoud Ahmadinejad predicted yesterday that Iran's economy would grow eight percent over the next 12 months despite severe Western sanctions, as he presented his government's annual budget to parliament. Iran's defense spending would more than double under plans set out by Ahmadinejad yesterday.
"The budget is aimed at securing a growth rate of eight percent, higher than 7.3 percent growth in the current year. The budget bill for 1391 (the Iranian year starting on March 20) has been drawn up by taking into account the price of oil and the international economy," Ahmadinejad said, without giving a figure. The president said the public budget for 2012-13 was worth around $90 billion, with an increase of 127 percent in the defense budget. Ahmadinejad set out a $416 billion state budget for Iran's calendar and fiscal year, which runs this year from mid-March. That was 14 percent less than the 2011-2012 budget, which was set at $484 billion. The president did not elaborate on the defense spending, while telling that it would increase by around 127 percent. Iran's economy has been grappling with ratcheted-up sanctions imposed by the U.S. and the E.U.in an effort to pressure Tehran to drop nuclear activities suspected to include research for an atomic bomb. "Considering increasing pressure and threats against Iran, it was necessary to increase the defense budget," MP Jahanbakhsh Amini told Reuters. Iran has warned it would take drastic measures, including possibly closing the Strait of Hormuz at the entrance of the Gulf to tanker traffic, if its economy is brought to its knees, or the country is attacked.
'Too optimistic'
Parliamentary speaker Ali Larijani again underlined that threat yesterday, saying that while Iran considers "the Strait of Hormuz as the strait of peace, it will cut the hands of anyone who seeks [military] adventurism in the Persian Gulf and the Sea of Oman," the Islamic Republic News Agency reported. Iranian media said the budget was based on an oil price of $85 a barrel, which is below international crude prices. Brent crude rose above $111 per barrel yesterday, gaining for a second straight session on fears that tensions between Iran and the West may escalate further. The president has been accused by his hardline rivals, including lawmakers, of stoking price rises with profligate spending of petrodollars.
"The submitted budget is too optimistic. It is not compatible with the realities of our economy," said lawmaker Ali Akbar Olia.
Iran more than Doubles 2012 Budget for Defense
February 2, 2012
Source: Hurriyet Daily News
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Thepnimit "Mr. Knock" Sitmonchai, who owns 98 knockouts on his
professional record, will make his U.S. debut against Dean James of
Birmingham, England. The fight card will air live on AXS TV.
"Lion Fight fans have been asking us to bring Thepnimit 'Mr. Knock'
Sitmonchai, a star in Thailand who trains in one of the most
respected gyms in the country, to fight here in the U.S.," said
Lion Fight CEO Scott Kent in
a press release. "He's an aggressive and powerful fighter who has
more than earned his nickname in this sport, but World Muay Thai
Champion Dean James didn't hesitate to step up and take this fight.
Sitmonchai vs. James is one of the most exciting main events we've
put together."
Sitmonchai (115-38-5) is ranked seventh at 120 pounds at the highly
respected Lumpinee Stadium in Thailand.
A lightweight bout with a pair of veterans is the latest addition to July's quickly filling UFC 200 lineup.Filed under: News, UFC read news >>
The fight card is starting to take shape for the UFC's July return to network television.Filed under: News, UFC read news >>
This month's UFC on FOX 19 lineup got a small shakeup, and it's resulted in a new bout to close out the UFC Fight Pass prelims.Filed under: News, UFC read news >>
The lineup is set for next month's Legacy FC 55 event, which is heavy on Houston-area talent.Filed under: AXS TV Fights, News read news >>
The lineup has started to build for this summer's TUF 23 Finale in Las Vegas with the addition of three fights in support of the women's strawweight title headliner. Filed under: News, UFC read news >>
A lightweight fight between John Makdessi and Mehdi Baghdad is the latest addition to UFC 199.Filed under: News, UFC read news >>
A flyweight bout between Paddy Holohan and Willie Gates is the 13th fight slated for next month's UFC Fight Night 87 card.Filed under: News, UFC read news >>
After a few changes, the lineup is again set for next week's UFC on FOX 19 event.Filed under: News, UFC read news >>
With three new bouts in a trio of weight classes, the main card is set for June's WSOF 31 event.Filed under: News, WSOF read news >>
The UFC on FOX 19 main card lineup continued to be ravaged today when UFC announced Lyoto Machida was out of Saturday's co-main event showdown with Dan Henderson. Check out some of the strongest reac read news >>


text:
SmartScore 99
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Here's the question you clicked on:
t = 2π √l/g Re-arrange to make g the subject.
\[\large t=2\pi \frac{\sqrt \ell}{g}\]Is that formatted correctly? With the way it's written, it's a little hard to tell whether or not you have the g placed in the square root.
If this is correct, here are the steps we would take: ~Multiply both sides by g,\[\large g t=2\pi \frac{\sqrt \ell}{\cancel g}\cancel g\]The g's will cancel out on the right, ~Divide both sides by t,\[\large \frac{g \cancel t}{\cancel t}=2\pi \frac{\sqrt \ell}{t}\]The t's will cancel on the left, giving us,\[\large \color{brown}{g=2\pi \frac{\sqrt \ell}{t}}\]
Alternatively, if you meant to write,\[\large t=2\pi \sqrt{\frac{\ell}{g}}\]We would start by writing it like this,\[\large t=2\pi \dfrac{\sqrt \ell}{\sqrt g}\]Then we would apply similar steps to the last method, ~Multiply both sides by \(\sqrt g\), \[\large t \sqrt g=2\pi \frac{\sqrt \ell}{\cancel{\sqrt g}}\cancel{\sqrt g} \qquad \rightarrow \qquad t \sqrt g=2\pi \sqrt \ell\]~Then divide both sides by t, \[\large \frac{\cancel t \sqrt g}{\cancel t}=2\pi\frac{\sqrt \ell}{t} \qquad \rightarrow \qquad \sqrt g=2\pi \frac{\sqrt \ell}{t}\] ~Then we'll finish up by squaring both sides,\[\large \left(\sqrt g\right)^2=\left(2\pi \frac{\sqrt \ell}{t}\right)^2 \qquad \rightarrow \qquad g=2^2 \pi^2\frac{(\sqrt \ell)^2}{t^2}\]When we square a term, we square `every part of it` as I have done above. Which gives us,\[\large \color{brown}{g=4\pi^2\frac{\ell}{t^2}}\]
Thank you, that was very helpful and easy to understand :)


text:
Choosing an Investment AdvisorSmall business owners – choosing the right financial advisor can make all the difference in the success you have with your stock investments. Try to visualise how a financial advisor might meet your needs and expectations, and when you start looking for the ideal candidate, be sure to interview more than one person.
Always keep in mind that the term 'advisor' has no precise legal meaning, so, depending on the context, it might be a bank branch employee, an advisor with a full service broker, or an advisor that works for a private banking or independent investment counselling firm. Just like in any of your small business endeavours, do your homework before you choose your advisor, and read through some of the following tips so that you know what to watch out for along the way.
Can the Advisor Sell a Range of Products?
Before you decide on your advisor, make sure you clarify exactly what products she or he is qualified to sell. As an investor, you will probably want an advisor who is savvy in the full range of investment opportunities, but some can only legally sell one type of product (such as mutual funds). Additionally, watch out for advisors who only sell products that are promoted by her or his employer, as they may not be fully objective.
Is the Advisor Charging Fees Upfront?
Sometimes financial planners will propose the waving of upfront fees, with the proviso that you allow them to continuously manage your portfolio. In the long run, this can get pricey, so it's recommended that you pay the fees upfront for the advice, and then continue to manage your investments yourself using a discount broker.
Is the Advisor Overly Confident?
Although it's a good sign to have a financial advisor that is confident, beware if they are too confident. If you interview an advisor who claims she or he can pick stocks that will beat the market, or claims to be able to predict future markets, be sceptical. You want an advisor who is confident, but not arrogant.
Does the Advisor Promise Suspiciously High Returns?
The basic principle when it comes to buying shares is that the returns are always closely related to the risk. If an advisor is promising you above-market returns that seem too good to be true, then undisclosed risks may be involved. Don't hesitate to check to see that both the advisor and the employer are registered with regulatory authorities.
Can You Trust the Advisor?
After having the initial interview with your potential financial advisor, you should feel that she or he is not only competent, but also trustworthy. Just like in any businesses, trust is the backbone of a client-advisor relationship, so always go with your gut feeling and check out the advisor's background. If the advisor has repeatedly changed firms, or has been involved in disciplinary proceedings, then keep looking.
How Will the Advisor be Compensated?
Compensation is one of the most common points of contention between clients and their advisors, so you can get an idea of what your future relationship may be like by discussing the money up front. An advisor should be able to clearly explain how she or he will be paid, either from your account or a third party, without it feeling like you're pulling teeth. Remember that financial advice is never free, so you shouldn't be paying for advice you don't need.
It may seem like a lot of work to choose the right financial advisor, but you will be well rewarded when you are buying shares and watching them grow!
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