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|By PR Newswire
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|November 3, 2012 01:00 PM EDT
LA JOLLA, Calif., Nov. 3, 2012 /PRNewswire/ -- Regulus Therapeutics Inc. (NASDAQ:RGLS), a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, today announced that new preclinical data targeting microRNA-21 (miR-21) will be presented at 10:00 a.m. PDT on November 3, 2012 in a late-breaking poster session at the American Society of Nephrology's Kidney Week 2012, meeting in San Diego, CA, October 30—November 4, 2012.
Late-Breaker Poster Presentation on miR-21 - November 3, 2012 10:00 a.m. PDT
- Anti-miR-21 Protects Collagen IVα(3) Deficient Mice from Progression of Alport Disease-
Regulus scientists and its collaborator, Jeremy Duffield M.D., Ph.D., Associate Professor of Medicine in the Division of Nephrology at the University of Washington, will present data demonstrating that therapeutic oligonucleotides targeting miR-21 (anti-miR-21) reduces the severity of fibrosis and improves renal function in a rodent model of Alport syndrome. Regulus' miR-21 therapeutic development program, which is partnered with Sanofi, is currently in preclinical testing for both kidney fibrosis and hepatocellular carcinoma.
"We are pleased to present at Kidney Week and believe these data further validate that anti-miR-21 is a potential new therapy for human kidney disease," said Neil W. Gibson, Ph.D., Chief Scientific Officer of Regulus. "We're making good progress toward the selection of an anti-miR-21 clinical development candidate and are excited about the potential to bring this innovative treatment to patients with fibrotic diseases."
The abstract can be accessed at Regulus' website, http://www.regulusrx.com, in the Publications page.
About Regulus
Regulus Therapeutics Inc. (NASDAQ:RGLS) is a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs. Regulus is leveraging a mature therapeutic platform based on technology that has been developed over 20 years. Regulus works with a broad network of academic collaborators and leverages the oligonucleotide drug discovery and development expertise of its founding companies, Alnylam Pharmaceuticals (NASDAQ:ALNY) and Isis Pharmaceuticals (NASDAQ:ISIS). Regulus is advancing microRNA therapeutics toward clinical development in several areas, including oncology, fibrosis, hepatitis C and metabolic diseases. Regulus has formed strategic alliances with AstraZeneca, GlaxoSmithKline and Sanofi and a research collaboration with Biogen Idec.
For more information, please visit http://www.regulusrx.com.
Forward-Looking Statements
Statements contained in this press release regarding matters that are not historical facts are "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995, including statements associated with Regulus' expectations regarding future therapeutic and commercial potential of Regulus' business plans, technologies and intellectual property related to microRNA therapeutics being discovered and developed by Regulus. Because such statements are subject to risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Words such as "believes," "anticipates," "plans," "expects," "intends," "will," "goal," "potential" and similar expressions are intended to identify forward-looking statements. These forward-looking statements are based upon Regulus' current expectations and involve assumptions that may never materialize or may prove to be incorrect. Actual results and the timing of events could differ materially from those anticipated in such forward-looking statements as a result of various risks and uncertainties, which include, without limitation, risks associated with the process of discovering, developing and commercializing drugs that are safe and effective for use as human therapeutics, and in the endeavor of building a business around such drugs. These and other risks concerning Regulus' programs are described in additional detail in Regulus' SEC filings. All forward-looking statements contained in this press release speak only as of the date on which they were made. Regulus undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made.
SOURCE Regulus Therapeutics Inc.
You think you know what's in your data. But do you? Most organizations are now aware of the business intelligence represented by their data. Data science stands to take this to a level you never thought of – literally. The techniques of data science, when used with the capabilities of Big Data technologies, can make connections you had not yet imagined, helping you discover new insights and ask new questions of your data. In his session at @ThingsExpo, Sarbjit Sarkaria, data science team lead ...
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If there is anything we have learned by now, is that every business paves their own unique path for releasing software- every pipeline, implementation and practices are a bit different, and DevOps comes in all shapes and sizes. Software delivery practices are often comprised of set of several complementing (or even competing) methodologies – such as leveraging Agile, DevOps and even a mix of ITIL, to create the combination that's most suitable for your organization and that maximize your busines...
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Join IBM June 8 at 18th Cloud Expo at the Javits Center in New York City, NY, and learn how to innovate like a startup and scale for the enterprise. You need to deliver quality applications faster and cheaper, attract and retain customers with an engaging experience across devices, and seamlessly integrate your enterprise systems. And you can't take 12 months to do it.
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"How Much is Chuck Norris Net Worth"
Profession:Writer, Actor, Martial artist, Columnist
Date of Birth: Mar 10, 1940
Nicknames: Carlos Ray Norris, Ground Chuck, Chuck Norris, chuck_norris
Height: 1.78 m
Ethnicity: Scotch-Irish American, Cherokee
Country: United States of America
Date of Birth: Mar 10, 1940
Nicknames: Carlos Ray Norris, Ground Chuck, Chuck Norris, chuck_norris
Height: 1.78 m
Ethnicity: Scotch-Irish American, Cherokee
Country: United States of America
Chuck Norris
Chuck Norris Net Worth is $26 Million. Chuck Norris is an American martial artist and actor, with a net worth of $26 million. Chuck Norris has built his net worth from acting in major films such as Way of the Dragon, Code of Silence, The Delta Force,. Carlos Ray "Chuck" Norris (b...
Chuck Norris Net Worth is $26 Million.Chuck Norris Net Worth is $26 Million. Chuck Norris is an American martial artist and actor, with a net worth of $26 million. Chuck Norris has built his net worth from acting in major films such as Way of the Dragon, Code of Silence, The Delta Force, Carlos Ray "Chuck" Norris is an American martial artist and actor. After serving in the United States Air Force, he began his rise to fame as a martial artist and has since founded his own school, Chun Kuk Do. As a result of his "tough guy" image, an Internet phenomenon began in 2005 known as Chuck Norris facts, ascribing various implausible or even impossible feats to Norris.
Norris appeared in a number of action films, such as Way of the Dragon in which he starred alongside Bruce Lee, and was The Cannon Group's leading star in the 1980s. He next played the starring role in the television series Walker, Texas Ranger from 1993 to 2001.
Norris is a devout Christian and politically conservative. He has written several books on Christianity and donated to a number of Republican candidates and causes. In 2007 and 2008, he campaigned for former Arkansas Governor Mike Huckabee, who was running for the Republican nomination for President in 2008. In the 2012 electi...
Chuck Norris Latest News
Chuck Norris Thinks Chemtrails are Real
Why am I not the least bit surprised to find out that Chuck Norris, who would need several promotions to get to be merely an idiot, thinks chemtrails are real? In his latest Worldnetdaily column, he says the government is spraying us with dangerous vaccines.
Posted: April 27, 2016, 4:30 am
Chicken-Fried News: Bacon burglar
OKC is home to a man from the future who has stolen Chuck Norris' moves. Dante Rashad Anderson took his extensive knowledge of what's to be to two fast food chains to grab some grub. FoxNews.com reported that he yelled at Carl's Jr. employees and ...
Posted: May 5, 2016, 6:15 am
Chuck Norris Writes Article On Chemtrail Cover-Up By The U.S Government
Actor and activist Chuck Norris may be considered one of the most popular action stars of his time, but people are once again talking about him for his new advocacy. Norris, 76, recently wrote an article at World Net Daily to talk about conspiracies ...
Posted: April 26, 2016, 5:02 am
Chuck Norris' Tight Wig Affects His Brain: The Chemtrail Conspiracy
Chuck Norris is the sort of actor you wish had just faded away after "Walker, Texas Ranger," because the sort of insanity that he has spewed since then really wears away at any cool persona he may have once had. Norris now spends a lot of his time ...
Posted: May 2, 2016, 6:44 am
D.A.R.E. Olympics Build Self Esteem And Character
"This event is named after Chuck Norris," Shay explained. "And that's Chuck Norris badge number one-thirty-six of the Mansfield Police department. This is not the famous Chuck Norris the actor. Chuck cared about the community. He cared about the little guy ...
Posted: May 1, 2016, 4:32 am
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Robert Stoll
Assistant Professor of Management
Dr. Bob Stoll joined Ashland University in 2012. He earned both B.S. and MBA degrees from the Rochester Institute of Technology, an M.S. in Mechanical Engineering from Case Western University and a Ph.D. from Cleveland State University in Operations and Supply Chain Management. He has extensive industrial experience as an engineer, plant manager, general manager and technical director. His recent research has focused on collaborative planning forecasting replenishment.
Faculty Spotlight
Dr. Hongxia Wang , Assistant Professor of Finance, joined Ashland University in 2009. Her areas of expertise include corporate finance, corporate governance, CEO turnover, succession,...Read more


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Nvidia ION-based nettops shown off at Computex
For those of you that have been waiting to see some more Nvidia ION-based systems, the company delivered a wide range of nettops during its first press conference a day ahead of the official opening of Computex.
The models shown were a mixed bag, with some being well designed and thought out, while others seemed to have been thrown together in a rush.
The two best looking models came from Foxconn and Pegatron, as not only were they the slimmest systems on display, but they also offered some of the best connectivity options.
Japanese Mouse Computer and MSI have the largest models on display and although both manufacturers offered optical drives, we're not sure about the justifications for the larger chassis, especially as neither models seemed very well thought out.
Local Taiwanese PMP maker FunTwist also had a rather decent looking model on show with a nicely crafted aluminium chassis. Sadly none of the systems on display were working.
On display was also an all-in-one system from ECS called the Morph (pictured), which offered the option of either being used on a desk or being wall mounted with a screen that could be folded horizontally for when the system is wall mounted. This was also the only working demo system apart from a Lenovo S12 netbook.
Google is shutting down Picasa: What'll happen to your photos and videos?
Win a $1000 iTunes gift card for music, apps, games and more
52 of the best tech life hacks
Flow is a new automation tool just like IFTTT - but Microsoft made it
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- 33 incredible photographers to follow on Instagram right now
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|By RealWire News Distribution
Article Rating:
|February 19, 2014 05:14 AM EST
Portfolio Includes New Entry-Level Price-Point Configurations for HFT, Network/Security Appliance OEMs, and Government/Telecom Applications
EUROPEAN INFORMATION SECURITY SUMMIT 2014, LONDON and COSTA MESA, Calif, 18 February 2014 - Emulex Corporation (NYSE:ELX), a leader in network connectivity, monitoring and management, today announced its next generation of EndaceDAG™ Data Capture Cards, which ensure 100 per cent packet capture on any network, regardless of packet size, interface type or network load. The next generation EndaceDAG card portfolio includes new low-cost configurations that bring high performance data capture technology to markets that previously had to settle for less-capable data capture technology. The next generation EndaceDAG Data Capture Cards will come in base, standard and premium packages, allowing users in the government, high frequency trading (HFT), telecommunications, network and application performance management (NPM and APM) service provider, as well as security event information management (SEIM) markets to maximise the functional needs based on their application.
"Our EndaceDAG Cards have been providing consistent, reliable, high performance packet capture for more than a decade and are the best possible foundation for customers' proprietary, internally developed network visibility solutions," said Mike Riley, senior vice president and general manager of the Endace Division of Emulex. "These new offerings allow us to bring these capabilities to several new target markets to address a new class of customers with a solution that provides the 100 per cent data capture and nanosecond-level timing accuracy that we are known for, but at a significantly lower price-point. The combination of the next generation EndaceDAG Cards for data capture and the new Emulex OneConnect® OCe14000 network interface card for server connectivity provide telecom customers with a best-in-breed solution for connecting and monitoring their networks."
The next generation of EndaceDAG Data Capture Cards have extended features and capabilities that provide reliable, accurate time stamping for high-bandwidth enterprise network monitoring, including:
Doubled Performance with PCI Express 3.0 Support: The next generation EndaceDAG Cards provide an 8-lane PCI Express 3.0 (PCIe) interface, allowing nearly twice the transfer rate of PCIe 2.0/2.1 interfaces and 40GbE wire-speed data capture with the forthcoming 40GbE upgrade kit for the quad-port EndaceDAG Card.
Increased ROI with Precision Timing Protocol Support: Select configurations of the next generation EndaceDAG Cards will support the precision timing protocol (PTP), which is especially important for HFT markets where sub-microsecond timing accuracy is critical. PTP reduces costs associated with accurate time stamping by providing a common highly accurate time source at a fraction of the cost of specialised network time appliances (e.g. GPS receivers). EndaceDAG Cards will provide a dedicated 1Gb Ethernet (1GbE) port for PTP, eliminating the need to use one of the 10GbE data ports for PTP.
Industry Leading Port Density Advantage: The next generation EndaceDAG Cards will be offered in both dual-port and quad-port 10GbE configurations. In addition, the dedicated PTP port effectively doubles port density and halves the price per port for HFT markets, resulting in a 2:1 port density advantage for customers using a dual-port card and a 4:1 port density advantage for customers using a quad-port card in PTP applications, when compared to data acquisition cards that do not provide a dedicated PTP port.
Operational Expenditure (OPEX) Savings and Investment Protection with Open Architecture: Next generation EndaceDAG Cards are based on an "open systems" architecture, including open source (GPL) drivers, a field-programmable gate array (FPGA) based design, and EndaceDAG application programming interface (API). These capabilities provide investment protection by allowing users to customise systems designed around the next generation EndaceDAG Cards and leverage the work of other users in the open-source community to bring new features and functionality into their custom solutions.
Highest Performance and Reliability: EndaceDAG Cards capture 100 per cent of available network traffic from the wire, time stamped and transferred to host memory without loss and with no impact to live network traffic. By supporting a large number of receive streams, load balancing and time stamping of network data on every server, metrics can be collected and analysed to ensure service provider performance, transaction usage and performance, and can make network key performance indicators (KPIs), such as network latency and packet loss more measureable and actionable. The ability to capture 100 per cent of the network traffic transiting a link provides network organisations clear visibility to detect and investigate issues at the network packet-level, and lower time-to-resolution (TTR).
The next generation EndaceDAG Data Capture Cards will be available in three feature bundles (Premium, Standard, and Basic). These configurations will be available across a planned MSRP range of $4,450 to $14,950. This enables customers to leverage the market-leading performance and accuracy of EndaceDAG Cards in markets where they were previously cost-prohibitive. Key capabilities of the feature bundles include:
Premium: The Premium configuration provides all of the features of our current-generation EndaceDAG Card and in addition, with a strong focus on supporting data capture for encapsulated protocols like GTP. In addition to supporting Ethernet protocols, the Premium configuration and will support protocols such as GTP, IPinIP, and GRE as well as OC3/12/48/192 and 10GbE WAN protocols, and will support load-balancing and filtering across a variety of encapsulated protocols, making it an ideal capture solution for mobility markets. The Premium configuration also increases the number of RX/TX streams to 64 receive (RX) and 4 transmit (TX), with up to 64GB of memory per stream. Like the EndaceDAG Standard configuration, the Premium configuration also provides support for PTP and proprietary network packet broker (NPB) timing protocols. The Premium configuration will be offered in both dual- and quad-port 10GbE cards.
Standard: The Standard configuration is an ideal solution for markets such as HFT, which require highly accurate time stamping. This configuration provides the same RX/TX stream support and memory/stream capabilities as our current-generation EndaceDAG Card, and support for both PTP and proprietary NPB timing signals. It also supports load balancing including the ability to load balance across VLANs and MPLS, allowing multiple cards within a server to be coupled together. The Standard configuration will be available in dual-port and quad-port 10GbE cards.
Basic: The Basic configuration provides basic data capture on 10GbE networks. It supports 16 RX and 2 TX streams, with up to 2GB of memory per stream with a maximum stream memory of 32GB. It will also provide the same load balancing capabilities as the Standard configuration. The Basic configuration will only be available as a dual-port 10GbE card.
As a part of the next generation EndaceDAG launch, Emulex is also launching the EndaceDAG beta program which will allow end users to start integrating the latest features in Endace's data capture technology into their applications. Beta program participants will have early access to the hardware, software, open source drivers and EndaceDAG API during the evaluation period, as well as discounts on products, equipment and/or software upgrades. To learn more about the beta program, please visit http://www.emulex.com/NextGenDAG.
"The ability to capture and analyse network behaviour for incident detection is becoming increasingly challenging for network and security operations staff that have upgraded to 10GbE and/or migrated to virtual, hybrid or cloud architectures," said Bob Laliberte, senior analyst at Enterprise Strategy Group. "The ability to collect and access packet -level data is critical to analysing the root cause of network issues, however capturing all of the packets on high-speed networks can prove to be challenging. To help overcome these issues Emulex has introduced its next generation EndaceDAG Data Capture Cards, that offer a range of affordable configuration options for data visualisation with minimal latency, regardless of packet size, interface type or network load."
Tweet this: #Emulex Announces Next Gen EndaceDAG Data Capture Cards for Network Monitoring Apps: http://ow.ly/tBdTE
Additional Resources:
Learn more about next generation EndaceDAG Data Capture Card technology here: http://www.emulex.com/NextGenDAG
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About Emulex
Emulex, a leader in network connectivity, monitoring and management, provides hardware and software solutions for global networks that support enterprise, cloud, government and telecommunications. Emulex's products enable unrivalled end-to-end application visibility, optimisation and acceleration. The Company's I/O connectivity offerings, including its line of ultra high-performance Ethernet and Fibre Channel-based connectivity products, have been designed into server and storage solutions from leading OEMs, including Cisco, Dell, EMC, Fujitsu, Hitachi, HP, Huawei, IBM, NetApp and Oracle, and can be found in the data centres of nearly all of the Fortune 1000. Emulex's monitoring and management solutions, including its portfolio of network visibility and recording products, provide organisations with complete network performance management at speeds up to 100Gb Ethernet. Emulex is headquartered in Costa Mesa, Calif., and has offices and research facilities in North America, Asia and Europe. For more information about Emulex (NYSE:ELX) please visit http://www.Emulex.com.
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"Safe Harbor" Statement
"Safe Harbor'' Statement under the Private Securities Litigation Reform Act of 1995: With the exception of historical information, the statements set forth above, contain forward-looking statements that involve risk and uncertainties. We expressly disclaim any obligation or undertaking to release publicly any updates or changes to these forward-looking statements that may be made to reflect any future events or circumstances. We wish to caution readers that a number of important factors could cause actual results to differ materially from those in the forward-looking statements. These factors include the possibility that we may not realise the anticipated benefits from the acquisition of Endace on a timely basis or at all, and may be unable to integrate the technology, operations and personnel of Endace into our existing operations in a timely and efficient manner. In addition, intellectual property claims, with or without merit, that could result in costly litigation, cause product shipment delays, require us to indemnify customers, or require us to enter into royalty or licensing agreements, which may or may not be available. Furthermore, we have in the past obtained, and may be required in the future to obtain, licenses of technology owned by other parties. We cannot be certain that the necessary licenses will be available or that they can be obtained on commercially reasonable terms. If we were to fail to obtain such royalty or licensing agreements in a timely manner and on reasonable terms, our business, results of operations and financial condition could be materially adversely affected. Ongoing lawsuits, such as the action brought by Broadcom Corporation (Broadcom), present inherent risks, any of which could have a material adverse effect on our business, financial condition, or results of operations. Such potential risks include continuing expenses of litigation, loss of patent rights, monetary damages, injunctions against the sale of products incorporating the technology in question, counterclaims, attorneys' fees, incremental costs associated with product or component redesigns, liabilities to customers under reimbursement agreements or contractual indemnification provisions, and diversion of management's attention from other business matters. With respect to the continuing Broadcom litigation, such potential risks also include the adequacy of any sunset period to make design changes, the ability to implement any design changes, the availability of customer resources to complete any re-qualification or re-testing that may be needed, the ability to maintain favorable working relationships with Emulex suppliers of serializer/deserializer (SerDes) modules, and the ability to obtain a settlement which does not put us at a competitive disadvantage. In addition, the fact that the economy generally, and the technology and storage market segments specifically, have been in a state of uncertainty makes it difficult to determine if past experience is a good guide to the future and makes it impossible to determine if markets will grow or shrink in the short term. Continued weakness in domestic and worldwide macro-economic conditions, related disruptions in world credit and equity markets, and the resulting economic uncertainty for our customers, as well as the storage and converged networking market as a whole, has and could continue to adversely affect our revenues and results of operations. As a result of these uncertainties, we are unable to predict our future results with any accuracy. Other factors affecting these forward-looking statements include but are not limited to the following: faster than anticipated declines in the storage networking market, slower than expected growth of the converged networking market or the failure of our Original Equipment Manufacturer (OEM) customers to successfully incorporate our products into their systems; our dependence on a limited number of customers and the effects of the loss of, decrease in or delays of orders by any such customers, or the failure of such customers to make timely payments; the emergence of new or stronger competitors as a result of consolidation movements in the market; the timing and market acceptance of our products or our OEM customers' new or enhanced products; costs associated with entry into new areas of the network, server and storage technology markets; the variability in the level of our backlog and the variable and seasonal procurement patterns of our customers; any inadequacy of our intellectual property protection and the costs of actual or potential third-party claims of infringement and any related indemnity obligations or adverse judgments; the effect of any actual or potential unsolicited offers to acquire us; proxy contests or the activities of activist investors; impairment charges, including but not limited to goodwill and intangible assets; changes in tax rates or legislation; the effects of acquisitions; the effects of terrorist activities, natural disasters, and any resulting disruption in our supply chain or customer purchasing patterns or any other resulting economic or political instability; the highly competitive nature of the markets for our products as well as pricing pressures that may result from such competitive conditions; the effects of changes in our business model to separately charge for software; the effect of rapid migration of customers towards newer, lower cost product platforms; transitions from board or box level to application specific integrated circuit (ASIC) solutions for selected applications; a shift in unit product mix from higher-end to lower-end or mezzanine card products; a faster than anticipated decrease in the average unit selling prices or an increase in the manufactured cost of our products; delays in product development; our reliance on third-party suppliers and subcontractors for components and assembly; our ability to attract and retain key technical personnel; our ability to benefit from our research and development activities; our dependence on international sales and internationally produced products; changes in accounting standards; and any resulting regulatory changes on our business. These and other factors could cause actual results to differ materially from those in the forward-looking statements and are discussed in our filings with the Securities and Exchange Commission, including our recent filings on Forms 10-K and 10-Q, under the caption "Risk Factors."
All trademarks, trade names, service marks, and logos referenced herein belong to their respective companies.
Source: RealWire
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trust and privacy in their ecosystem. Assurance and protection of device identity, secure data encryption and authentication are the key security challenges organizations are trying to address when integrating IoT devices. This holds true for IoT applications in a wide range of industries, for example, healthcare, consumer devices, and manufacturing. In his session at @ThingsExpo, Lancen LaChance, vice president of product management, IoT solutions at GlobalSign, will teach IoT developers how t...
May. 4, 2016 05:30 AM EDT Reads: 353
The IETF draft standard for M2M certificates is a security solution specifically designed for the demanding needs of IoT/M2M applications. In his session at @ThingsExpo, Brian Romansky, VP of Strategic Technology at TrustPoint Innovation, will explain how M2M certificates can efficiently enable confidentiality, integrity, and authenticity on highly constrained devices.
May. 4, 2016 05:00 AM EDT Reads: 1,221
Manufacturers are embracing the Industrial Internet the same way consumers are leveraging Fitbits – to improve overall health and wellness. Both can provide consistent measurement, visibility, and suggest performance improvements customized to help reach goals. Fitbit users can view real-time data and make adjustments to increase their activity. In his session at @ThingsExpo, Mark Bernardo Professional Services Leader, Americas, at GE Digital, will discuss how leveraging the Industrial Interne...
May. 4, 2016 04:45 AM EDT Reads: 1,318
There is an ever-growing explosion of new devices that are connected to the Internet using "cloud" solutions. This rapid growth is creating a massive new demand for efficient access to data. And it's not just about connecting to that data anymore. This new demand is bringing new issues and challenges and it is important for companies to scale for the coming growth. And with that scaling comes the need for greater security, gathering and data analysis, storage, connectivity and, of course, the...
May. 4, 2016 03:30 AM EDT Reads: 1,154
The IoTs will challenge the status quo of how IT and development organizations operate. Or will it? Certainly the fog layer of IoT requires special insights about data ontology, security and transactional integrity. But the developmental challenges are the same: People, Process and Platform. In his session at @ThingsExpo, Craig Sproule, CEO of Metavine, will demonstrate how to move beyond today's coding paradigm and share the must-have mindsets for removing complexity from the development proc...
May. 4, 2016 03:00 AM EDT Reads: 788
Artificial Intelligence has the potential to massively disrupt IoT. In his session at 18th Cloud Expo, AJ Abdallat, CEO of Beyond AI, will discuss what the five main drivers are in Artificial Intelligence that could shape the future of the Internet of Things. AJ Abdallat is CEO of Beyond AI. He has over 20 years of management experience in the fields of artificial intelligence, sensors, instruments, devices and software for telecommunications, life sciences, environmental monitoring, process...
May. 3, 2016 11:00 PM EDT Reads: 1,251
Increasing IoT connectivity is forcing enterprises to find elegant solutions to organize and visualize all incoming data from these connected devices with re-configurable dashboard widgets to effectively allow rapid decision-making for everything from immediate actions in tactical situations to strategic analysis and reporting. In his session at 18th Cloud Expo, Shikhir Singh, Senior Developer Relations Manager at Sencha, will discuss how to create HTML5 dashboards that interact with IoT devic...
May. 3, 2016 10:00 PM EDT Reads: 1,342
We're entering the post-smartphone era, where wearable gadgets from watches and fitness bands to glasses and health aids will power the next technological revolution. With mass adoption of wearable devices comes a new data ecosystem that must be protected. Wearables open new pathways that facilitate the tracking, sharing and storing of consumers' personal health, location and daily activity data. Consumers have some idea of the data these devices capture, but most don't realize how revealing and...
May. 3, 2016 09:45 PM EDT Reads: 361
SYS-CON Events announced today that Ericsson has been named "Gold Sponsor" of SYS-CON's @ThingsExpo, which will take place on June 7-9, 2016, at the Javits Center in New York, New York. Ericsson is a world leader in the rapidly changing environment of communications technology – providing equipment, software and services to enable transformation through mobility. Some 40 percent of global mobile traffic runs through networks we have supplied. More than 1 billion subscribers around the world re...
May. 3, 2016 08:45 PM EDT Reads: 1,288
We've worked with dozens of early adopters across numerous industries and will debunk common misperceptions, which starts with understanding that many of the connected products we'll use over the next 5 years are already products, they're just not yet connected. With an IoT product, time-in-market provides much more essential feedback than ever before. Innovation comes from what you do with the data that the connected product provides in order to enhance the customer experience and optimize busi...
May. 3, 2016 08:30 PM EDT Reads: 1,221
The increasing popularity of the Internet of Things necessitates that our physical and cognitive relationship with wearable technology will change rapidly in the near future. This advent means logging has become a thing of the past. Before, it was on us to track our own data, but now that data is automatically available. What does this mean for mHealth and the "connected" body? In her session at @ThingsExpo, Lisa Calkins, CEO and co-founder of Amadeus Consulting, will discuss the impact of wea...
May. 3, 2016 08:00 PM EDT Reads: 1,066
A critical component of any IoT project is the back-end systems that capture data from remote IoT devices and structure it in a way to answer useful questions. Traditional data warehouse and analytical systems are mature technologies that can be used to handle large data sets, but they are not well suited to many IoT-scale products and the need for real-time insights. At Fuze, we have developed a backend platform as part of our mobility-oriented cloud service that uses Big Data-based approache...
May. 3, 2016 04:15 PM EDT Reads: 360
In his session at @ThingsExpo, Chris Klein, CEO and Co-founder of Rachio, will discuss next generation communities that are using IoT to create more sustainable, intelligent communities. One example is Sterling Ranch, a 10,000 home development that – with the help of Siemens – will integrate IoT technology into the community to provide residents with energy and water savings as well as intelligent security. Everything from stop lights to sprinkler systems to building infrastructures will run ef...
May. 3, 2016 03:15 PM EDT Reads: 1,200
Digital payments using wearable devices such as smart watches, fitness trackers, and payment wristbands are an increasing area of focus for industry participants, and consumer acceptance from early trials and deployments has encouraged some of the biggest names in technology and banking to continue their push to drive growth in this nascent market. Wearable payment systems may utilize near field communication (NFC), radio frequency identification (RFID), or quick response (QR) codes and barcodes...
May. 3, 2016 02:30 PM EDT Reads: 956
Whether your IoT service is connecting cars, homes, appliances, wearable, cameras or other devices, one question hangs in the balance – how do you actually make money from this service? The ability to turn your IoT service into profit requires the ability to create a monetization strategy that is flexible, scalable and working for you in real-time. It must be a transparent, smoothly implemented strategy that all stakeholders – from customers to the board – will be able to understand and comprehe...
May. 3, 2016 12:30 PM EDT Reads: 1,193
You deployed your app with the Bluemix PaaS and it's gaining some serious traction, so it's time to make some tweaks. Did you design your application in a way that it can scale in the cloud? Were you even thinking about the cloud when you built the app? If not, chances are your app is going to break. Check out this webcast to learn various techniques for designing applications that will scale successfully in Bluemix, for the confidence you need to take your apps to the next level and beyond.
May. 3, 2016 12:15 PM EDT Reads: 1,595
SYS-CON Events announced today that Peak 10, Inc., a national IT infrastructure and cloud services provider, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. Peak 10 provides reliable, tailored data center and network services, cloud and managed services. Its solutions are designed to scale and adapt to customers' changing business needs, enabling them to lower costs, improve performance and focus inter...
May. 3, 2016 12:00 PM EDT Reads: 1,376
So, you bought into the current machine learning craze and went on to collect millions/billions of records from this promising new data source. Now, what do you do with them? Too often, the abundance of data quickly turns into an abundance of problems. How do you extract that "magic essence" from your data without falling into the common pitfalls? In her session at @ThingsExpo, Natalia Ponomareva, Software Engineer at Google, will provide tips on how to be successful in large scale machine lear...
May. 3, 2016 09:45 AM EDT Reads: 1,468
You think you know what's in your data. But do you? Most organizations are now aware of the business intelligence represented by their data. Data science stands to take this to a level you never thought of – literally. The techniques of data science, when used with the capabilities of Big Data technologies, can make connections you had not yet imagined, helping you discover new insights and ask new questions of your data. In his session at @ThingsExpo, Sarbjit Sarkaria, data science team lead ...
May. 3, 2016 07:00 AM EDT Reads: 1,138
SYS-CON Events announced today that Fusion, a leading provider of cloud services, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. Fusion, a leading provider of integrated cloud solutions to small, medium and large businesses, is the industry's single source for the cloud. Fusion's advanced, proprietary cloud service platform enables the integration of leading edge solutions in the cloud, including cloud...
May. 2, 2016 10:00 AM EDT Reads: 2,707


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Relevant offers
National business
The Institute of Chartered Accountants (NZICA) has joined the chorus of dismay over the Inland Revenue Department's decision to retrospectively tax accommodation allowances.
The accounting industry body says it is "deeply concerned" about the new tax, and says it will affect the Christchurch rebuild.
The change will have a significant impact on industries which rely on itinerant workers, such as agriculture, the film industry, and the effort to rebuild the quake-shattered city, NZICA says.
The new rule, announced in a statement yesterday, will mean that employers have to pay PAYE on any accommodation allowance an employee gets when working away from home.
NZICA acting general manager tax, Jolayne Trim, said the decision to make the rule change retrospective was a particular surprise.
IRD was recommending firms voluntarily disclose accommodation allowance payments going back as far as four years, she said.
It may also have an impact on payments such as Working for Families. "It could affect Kiwi families if it suddenly turns out their income is higher.
"NZICA considers this to be a retrospective law change of the worst kind.
"Inland Revenue is taking the chance that taxpayers will not have the resources available to question the commercial impracticality of its announcement," Trim said.
KPMG said the IRD's statement was "contrary to long-standing practice", where it was considered there was no benefit from such an allowance and no tax payable, if a worker had a home elsewhere.
The IRD "seems to be trying to rewrite history", KPMG said. "We are not convinced IRD has this right from either a technical or policy point of view." A retrospective change was not justified nor in line with good tax policy.
Accommodation may not be taxable when it was just overnight or for a short-term stay by a worker when they have to be away from home for work.
Deloitte chief executive Thomas Pippos said the IRD approach would be seen as "disappointing and unreasonable" by the tax community.
"The reality is that from a revenue perspective the amounts involved are trivial in aggregate, but can add up to a reasonable amount on a case by case basis."
- BusinessDay.co.nz
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Retractions are on the rise. But reams of flawed research papers persist in the scientific literature. Is it time to change the way papers are published?
Next Generation: Microfluidics for the Dish
October 4, 2011|
A new device for directing fluids is designed to deliver chemical cues directly to petri dishes without disturbing cells.


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Gray Basic Flat Front Double Knee School Uniform Boys Pants 4-7These boys pants are a must have for any school uniform wardrobe by Classroom Uniforms.
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Have been here 3 or 4 times and never had a bad meal. Normally I get bbq ribs and wife gets bbq sandwich, all good. Plus they have Killion's which makes the meal even better.
Townsend Barbecue
1. Smoky Junction Restaurant
7753 E Lamar Alexander PkwyTownsend, TN 37882
2. Smokin Joes
7753 E Lamar Alexander Pkwy , Townsend, Tn 37882Townsend, TN 37882
3. Smokey Mountain BBQ
7305 E Lamar Alexander PkwyTownsend, TN 37882
4. Little River Bar-B-QMenu
Have been here 3 or 4 times and never had a bad meal. Normally I get bbq ribs and wife gets bbq sandwich, all good. Plus they have Killion's which m…
5. Trailhead Steakhouse
I had the sirloin and it was great blackened with blue cheese crumbles. Sides were well portioned and the price was reasonable. The wife had the tro…
6. Fat Boys Barbecue
3269 Wears Valley RdSevierville, TN 37862
From Business: Fat Boy's Bar B Que is located in beautiful Wears Valley, TN. We offer the best in slow smoked Bar B Que including Pulled Pork, Beef Brisket, Baby Back Ribs, Smoked…
7. Bar B Q Bootleggers On The Rvr
2881 Wears Valley RdSevierville, TN 37862
8. Smokin' Ed's BBQ
We were in Pigeon Forge last weekend for the Grand Rod Run and were sent to eat at Smokin' Ed's BBQ there by other Rod Run visitors that were sittin…
9. Corky'sMenu
10. Hungry Bear Bbq Number Two
490 E ParkwayGatlinburg, TN 37738
11. Full Service BBQMenu
I'd give these guys 4 stars just because they pump that amazing BBQ smell into my car everyday when I drive home :)
12. Texas Roadhouse
334 Fountain View CirAlcoa, TN 37701
From Business: Texas Roadhouse is a steak restaurant providing legendary food with legendary service. Texas Roadhouse specializes in hand-cut steaks, fresh-baked bread, fall-off-t…
13. Buddy's Bar-B-QMenu
518 Foothills PlzMaryville, TN 37801
14. Boss Hogg's Bar B' QueMenu
1198 Wears Valley RdPigeon Forge, TN 37863
From Business: Boss Hogg's Bar B' Que is proud to deliver some of the best smoked brisket, sausage, ribs and other meats that make up our tasty menu here in the Smokies. Updated v…
15. Bennett's Pit Bar-B-QueMenu
Speedy and friendly service! Great food and good portions! Reasonable price. Best bbq place we found in the area.
16. Bennett's Pit Bar-B-QueMenu
714 River RdGatlinburg, TN 37738
From Business: Serving the area's best slow-smoked ribs, beef, chicken, sausage and pork for almost a quarter of a century! Come find out why we are voted BEST RIBS and BEST BBQ y…
17. Flying Pig Smokehouse
Nice man running his BBQ restaurant, did a great job making great BBQ sandwiches and waiting on us. Try him out.
18. Jb's Ribs & More
GREAT Food: AMAZING Love It Gooooo Soooo Godd Mmmmm Hmm :)
19. Sweet P's Barbecue & Soul House
Best ribs around. No BS, just GREAT food, made the right way. You don't have to pretend you like the food so as to not upset the delicate sensibilit…
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Not on the main drag. Good pulled pork
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The girl who greeted was incredibly awkward...deep starer. Food was good though.
22. Westgate Smokehouse GrillMenu
915 Westgate Resorts RdGatlinburg, TN 37738
From Business: The Westgate Smokehouse Grill is your destination for country style dining and mountain hospitality at its finest. Breakfast at the Westgate Smokehouse Grill is a S…
23. Buddys BBQ
806 High StMaryville, TN 37804
24. Buddy's Bar-B-Q
1120 Bridgeway DrMaryville, TN 37801
25. Ol' Towne BBQ
1540 Upper Middle Creek RdSevierville, TN 37876
26. Parton's Smokin Butz BBQMenu
Went here to eat in November 17, 2012. Was in town for the The Battle of the Rocky Top. Didn't want any BBQ, but they have all types of food and a…
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728 ParkwaySevierville, TN 37862
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11612 Chapman HwySeymour, TN 37865
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The food is to die for especially the ribs. They have a variety of different choices on there menu for dinner. They also have a Daily Lunch meun whi…
30. Happy Jacks BBQ
728 ParkwaySevierville, TN 37862


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This reproduction of a handout photograph released by the Philippine Department of National Defense yesterday shows what the Philippine government says is an aerial image taken on Aug. 31 of alleged concrete blocks on the Scarborough Shoal in the South China Sea. Manila accused China of laying the blocks.Sep 04, 2013FULL STORY
Photo: AFP / Philippine Department of National Defense
This photo has been viewed 277 times.
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Diabetes Health Center
Diabetic Retinopathy - What Happens
Diabetic retinopathy begins as a mild disease. During the early stage of the disease, the small blood vessels in the retina become weaker and develop small bulges called microaneurysms. These microaneurysms are the earliest signs of retinopathy and may appear a few years after the onset of diabetes. They may also burst and cause tiny blood spots (hemorrhages) on the retina. But they do not usually cause symptoms or affect vision. This is called nonproliferative retinopathy. At this stage, treatment is not required.
As retinopathy progresses, fluid and protein leak from the damaged blood vessels and cause the retina to swell. This may cause mild to severe vision loss, depending on which parts of the retina are affected. If the center of the retina (macula) is affected, vision loss can be severe. Swelling and distortion of the macula (macular edema), which results from a buildup of fluid, is the most common complication of retinopathy. Macular edema treatment usually works to stop and sometimes reverse your loss of vision.
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In some people, retinopathy gets worse over the course of several years and progresses to proliferative retinopathy. In these cases, reduced blood flow to the retina stimulates the growth (proliferation) of fragile new blood vessels on the surface of the retina. As the new blood vessels multiply, one or more complications may develop and damage the person's vision. These complications can include:
- The formation of scar tissue that pulls on the retina, which may lead to retinal detachment.
- Bleeding inside the eye (preretinal or vitreous hemorrhage).
- The growth of new blood vessels on the surface of the iris (rubeosis iridis), which eventually leads to a form of severe glaucoma called neovascular glaucoma.
Any of these later complications may cause severe, permanent vision loss.
In this article
WebMD Medical Reference from Healthwise
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'Line Of Duty' Finale Review - Crime Drama Signs Off With Two ...'Line of Duty' Series 3 has finally delivered its secrets - well, most of them - signing off with not one but two of those interrogation scenes that have made the show such quietly compelling drama, right up to the point we had a frantic, ... Huffington Post UK, 3 days ago
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AFP - fbl-FRA-Ligue1-Marseille-LouisDreyfuss lead
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Float: Up to the Bedrock
by Benny Kwok Situated atop a hill in Purcell's Cove, Float is surrounded by exposed bedrock and the remnants of a dense forest that was devastated by fire. PROJECT Float, Halifax, Nova Scotia ARCHITECT Omar Gandhi Architect Inc. TEXT ...Canadian Architect, 1 week ago
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CAPITOL HILL— With only about eight months left in office, President Barack Obama is still trying to fulfill his campaign promise to close down the U.S. detention center at Guantanamo Bay, Cuba. At its peak, close to 800 so-called enemy ...VOA News, 3 days ago Nikki Haley Called Out For Hypocrisy After Refusing To House Guantanamo Detainees Huffington Post, 3 days ago
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After 16 complaints, city builder finally in police net
Tripunithura: The Hill Palace police on Sunday arrested a Kochi-based builder on charges of cheating customers. Sreeni Parameswaran (41), managing director of Shwas Homes Private Ltd, Kaniyampuza, was arrested on a complaint filed by Benny ...Times of India, 2 weeks ago Builder Arrested for Duping Customers New Indian Express, 2 weeks ago
The Hill's 12:30 Report
If you'd like to subscribe to The Hill's midday political newsletter, please click here: http://bit.ly/1lsUchu BREAKING THIS A.M. -- BIG SCOTUS DECISION:The Supreme Court unanimously (!) ruled Monday that a state or locality is allowed to draw ...The Hill, 3 weeks ago
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baby + daddy moments
Posted 05/07/2013
Posted 05/07/2013
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Look how far your child has come.
Review your child's growth milestones.
Read about 3 years : Week 3.
Your growing child
Your 3-year-old: Friendships
Your ever-more-independent child is probably starting to develop some friendships. Read More
Your 3-year-old: Counting
Ask most 3-year-olds how old they are and they'll proudly raise the correct number of fingers. Read More
Your 3-year-old: Playing ball
Some call it the perfect toy. What is it? Read More
Your 3-year-old: Pearly whites
Your child probably has a full set of primary teeth by now. Read More
Your 3-year-old: Power of play
Preschoolers often work out complicated emotions in their play with animals. Read More
Learn more
What's next for your growing child?
Get a glimpse of what's to come.
Read about 3 years 2 months : Week 1.


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Opinion: Is street art really relevant anymore?
This week James Cartwright questions the relevance of street art as an underground art form and, more importantly, we want to hear what you think in the comment thread below…
Way way back in 1989 a young Shepard Fairey was showing a friend how to make stencils and inadvertently stumbled across an image that would go on to define the rest of his career – simultaneously changing the face of street art forever. The picture of wrestler Andre The Giant became an overnight sticker sensation on the American West Coast and subsequently worldwide, later rebranding to Obey; a name as ubiquitous as its Bristolian counterpart, Banksy.
Back then Obey was a very different beast to the one we know today, speaking out against rampant consumerism and a perceived Big Brother society. Stumbling across Shepard Fairey's iconic stickers was an excitingly personal experience, letting you know that he'd been there in the flesh to communicate a message of hope.
What began as a rebellious cultural phenomenon has since become a commercial brand in its own right. In recent years Fairey has produced promotional posters for the Obama electoral campaign, revamped his clothing brand from grungy slogan hoodies and jeans to a chic fashion outlet, designed an anniversary logo for The Rolling Stones and is currently holding a large retrospective of his work at the Stolen Space gallery in London. Not bad for a guy who cut his teeth tagging walls and running from the police.
But as with all successful street artists the progression from propagandist wall-painter to commercial commodity is an uneasy one, for my money devaluing the poignant messages his work once seemed to convey and calling into question the relevance of street art as an artistic subculture. Do we really believe the rebellious slogans of a man working comfortably within the confines of an industry as financially biased as the art world?
Before the internet took over our lives, street art served as a free platform for artists to publicly communicate their ideas and ideals, but now this can be achieved with Tumblr. Street artists were the progressive creative voice of a subculture, but now Brad and Angelina come to stock up on art at their shows. Given this new relationship with the mainstream do we really feel that street art is relevant anymore? The artists themselves still claim to be revolutionaries and their rich patrons purchase their work to buy into that credibility, but the anti-authority messages are harder to swallow in the white walls of a gallery where there's champagne on tap.
- Submit Saturdays: photographer and filmmaker Harry Israelson's bright, smart portfolio
- May Diary: where to go and what to see this month
- Crisp and vibrant design work from ECAL graduate Clement Rouzaud
- Portuguese illustrator Tiago Galo's plump little characters are oddly charming
- Matthew Butcher launches the Flood House that will travel around the Thames Estuary
- Haunting train-simulator-based animation by Jack Featherstone for Occult Orientated Crime
- Philip Coppola spends nearly 40 years illustrating New York City's Subway Stations
- LA studio Laundry creates amazing warped Simpsons idents for American channel FX
- Design Bridge creates new harp icon for Guinness
- Winning design for Tokyo 2020 Olympics unveiled
- Prince: 1958-2016
- Milton Glaser creates new look for Brooklyn Brewery


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Students investigate how much greenhouse gas (carbon dioxide and methane) their family releases into the atmosphere each year and relate it to climate change. To address this, students use the Environmental Protection Agency Personal Emissions Calculator to estimate their family's greenhouse gas emissions and to think about how their family could reduce those emissions.
In this role-playing activity, learners are presented with a scenario in which they determine whether the Gulf Stream is responsible for keeping northern Europe warm. They must also address the potential future of the Gulf Stream if polar ice were to continue melting. The students work in small groups to identify the issue, discuss the problem, and develop a problem statement. They are then asked what they need to know to solve the problem.
In this activity, students create graphs of real temperature data to analyze climate trends by analyzing the global temperature record from 1867 to the present. Long-term trends and shorter-term fluctuations are both evaluated. The data is examined for evidence of the impact of natural and anthropogenic climate forcing mechanisms on the global surface temperature variability. Students are prompted to determine the difficulties scientists face in using this data to make climate predictions.
In this hands-on engineering activity, students will build a tabletop wind turbine. Students get acquainted with the basics of wind energy and power production by fabricating and testing various blade designs for table-top windmills constructed from one-inch PVC pipe and balsa wood (or recycled materials). The activity includes lots of good media and Web resources supporting the science content.
Students go through the design process and the scientific method to test the effect of blade design on power output. There is an optional extension to use the data to create an optimal set of wind turbine blades.
This video highlights a team of scientists who work on reconstructing the mass extinction that occurred 250 million years ago, the end of the Permian Period, and wiped out the majority of life on our planet, resetting the evolution of life. Clues suggest that deadly bacteria might have set off a chemical chain reaction that poisoned the Permian seas and atmosphere.
This is a short NASA video on the water cycle. The video shows the importance of the water cycle to nearly every natural process on Earth and illustrates how tightly coupled the water cycle is to climate.
This interactive graphic outlines the carbon cycle, with clickable text boxes that explain and elaborate each component.
In this learning activity, students use a web-based carbon calculator to determine their carbon footprint on the basis of their personal and household habits and choices. Students identify which personal activities and household choices produce the most CO2 emissions, compare their carbon footprint to the U.S. and global averages, and identify lifestyle changes they can make to reduce their footprint.
In this lesson, students examine and interpret varied observational datasets and are asked to determine whether the data supports or does not support the statement: climate change is occurring in Colorado.


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Queerty is better as a member
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Tour de France route announced
Organisers expect stage finish in London
Organisers expect stage finish in London
Stage Three of the Tour de France next summer is expected to start in Cambridge and head south to London before making a circuit of the Olympic Park. It's reported it'll ultimately finish on the Mall with Buckingham Palace as a backdrop.
The finish will be the same one used for the Olympic road races last summer.
More than a million spectators watched the prologue in Central London in 2007 and police estimated more than 1.5 million people were roadside the following day for stage two to Canterbury.
Labour leader tells May Day rally his party 'stand absolutely against racism in any form'.
Video has emerged of a police car colliding with a cyclist and driving over a bike during a mass bike ride in central London.
Harlesden's James DeGale has successfully defended his IBF super middleweight title against Rogelio Medina.