text:
Bukowski, Butcher Billy
Bukowski, Butcher Billy
Not only will you be too terrified to ever get a job after watching this 1994 United Safety Council workplace safety video called Will You Be Here Tomorrow?, there's also a good chance you'll be too scared to ever actually leave your home. Neither Freddy Krueger nor Jason were ever as scary as the apparent horrors lurking in the average factory.
Here's the classic science experiment of mixing fire and alcohol in a large empty jug. It's always fun to see the perfect layer of flames slowly dance its way down the cylinder, like a slow drip of fire as the alcoholic vapors combust. Of course, the best part is that 'whoosh' sound it makes.
Some weeks can leave you feeling like you don't want to live on this planet anymore. For one hour and 34 blissful minutes you can move to the marshy forests of Dagobah, and leave your earthly problems behind you.
Really hope they make this movie.
For years now we've been reporting on the on-again, off-again development of The Jim Henson Company's The Happytime Murders, a puppet noir described as "Avenue Q meets L.A. Confidential." The project got a shot in the arm last year when STX Entertainment scooped it up, and now it's taking another big step forward by casting its first human. Jamie Foxx is in early talks to play the human half of the detective duo investigating a streak of puppet murders.
The Hollywood Reporter, which broke the Jamie Foxx Happytime Murders casting news. Brian Henson, son of Jim Henson and director of The Muppet Christmas Carol and Muppet Treasure Island, is on board to direct, as he has been since 2008. Erich and Jon Hoeber (Red, Battleship) wrote the latest version of the script, following earlier drafts by Todd Berger (It's a Disaster) and Dee Robertson.
The trade describes the project as a "dark, R-rated" action comedy and explains the plot as follows:
Happytime takes place in a world where humans and puppets coexist, with the puppets viewed as second-class citizens. When the puppet castmembers of 1980s children's TV show The Happytime Gang begin turning up dead, an alcoholic, disgraced LAPD detective-turned-private eye puppet takes the case with his former human partner.
Deadline has a little more to add, describing Foxx's character as a "type-A, take-no-prisoners human with a secret" and his partner as "a crass, hard-drinking puppet with a connection to one of the victims." The similarities to Avenue Q and L.A. Confidential are obvious, but The Happytime Murders also sounds a bit like Who Framed Roger Rabbit?, only with puppets instead of cartoons and an edgy R-rating instead of a family-friendly PG.
Foxx seems like a pretty great choice for the role. Not only is he the kind of big-name actor that could help a long-developing project like this pick up some steam, he's a versatile talent who can switch between serious and silly. He was last seen in Annie and Horrible Bosses 2 (and The Amazing Spider-Man 2, about which the less said the better), and is now shooting Edgar Wright's Baby Driver with Ansel Elgort and Kevin Spacey. Also on his to-do list is Robin Hood: Origins, a gritty retelling of the classic legend.
The post Jamie Foxx May Solve Crimes With a Puppet in The Jim Henson Company's 'The Happytime Murders' appeared first on /Film.
Even before the Punisher made his Marvel Cinematic Universe debut in the second season of Daredevil, rumors abounded about the possibility of a Punisher spinoff. He's a popular character to begin with, after all, and Jon Bernthal couldn't be a better choice to play him. Then the character actually appeared on the show, and proved to be everything fans had hoped for. The calls for a Punisher spinoff only got louder. And now, Marvel is finally ready to make its move.
A Punisher spinoff has reportedly been ordered by Marvel, with Bernthal set to return as the vigilante character. Steve Lightfoot (Hannibal) will write, executive produce, and serve as showrunner.
Entertainment Weekly broke the news of the Punisher spinoff. This makes Punisher the sixth Marvel series at Netflix, after Daredevil, Jessica Jones, and the upcoming Luke Cage, Iron Fist, and The Defenders. As of now, it's unclear whether Bernthal's Punisher will appear in The Defenders, an Avengers-style team-up which brings together Netflix's other four street-level heroes (Charlie Cox's Daredevil, Krysten Ritter's Jessica Jones, Mike Colter's Luke Cage, and Finn Jones' Iron Fist).
We've been hearing for a while that Netflix was eyeing the possibility of a Punisher solo series, though Marvel has insisted that nothing is official yet. According to Entertainment Weekly's sources, they'll make the official announcement later today. Vigilante Frank Castle definitely has enough of a following to lead his own project, and his grim and deadly antihero persona is a perfect fit for this darker, grittier corner of the Marvel Cinematic Universe.
Lightfoot is a veteran of British TV whose credits include Casualty and Hannibal. He began writing for the latter series in season 1 and was promoted to executive producer in season 2.
There's no word yet on when the Punisher series will get going, but while we wait for updates you can check out the first teaser image below:
The post Netflix Orders Marvel's 'Punisher' Spinoff appeared first on /Film.
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Sylvester Stallone is coming to television in an adaptation of Godfather author Mario Puzo's final novel, Omerta.
Deadline reports that The Weinstein Company backed series will follow Stallone as the "last great American don" Raymonde Aprile and his adopted nephew Astorre Viola. Chosen to succeed Aprile, Astorre comes to control the don's banking interests in a plot line that seems fairly reminiscent of The Godfather Part III.
While Stallone has produced and appeared in a number of reality TV series, this will be his first significant recurring dramatic role.
Magnificent Seven remake director Antonie Fuqua will direct and executive produce with Stallone. The production is also currently looking for a showrunner, a lead actress and a network to take on the event series.
In honor of the best backfire & comeuppance episode in South Park history, Kidrobot brings you a figure like no other. A.W.E.S.O.M.-O, a collectible that is fully-sculpted, and 6 inches of awesome design, for $59.99.
Here's what Kidrobot has to say:
"Technically known as A.W.E.S.O.M.-O 4000, hijinks ensue when Cartman does what Cartman does and acts like a choade. Disguising himself to learn Butters' deepest secrets…"
A.W.E.S.O.M.-O even comes with a removable head that reveals the half-starved face of Eric Cartman with only his toothpaste accessory for sustenance. I can safely say, this looks like one of the coolest collectibles I've seen, especially South Park wise. Since it's made its return to Kidrobot.com, I wouldn't wait to grab one. The uniqueness and detailed design will surely make it sell out again.
Makes me like Keanu more.
The kidnapped kitten at the center of the new comedy Keanu is obviously named after Keanu Reeves, the seemingly immortal star of Speed, Point Break, The Matrix, and John Wick, but we now know that the actor himself has a tiny cameo in the film. Keanu Reeves plays Keanu the cat. Well, technically he voices Keanu the cat in a scene where a character hallucinates during a crazy drug trip. However, this cameo almost didn't happen and we have Mr. Reeves' sister to thank for its existence.
Keanu, which is the big screen debut of beloved comedy duo Keegan-Michael Key and Jordan Peele, follows two best friends, one a lazy stoner and the other a boring suburbanite, who infiltrate the local criminal underworld when a beloved kitten is abducted by a dangerous gangster. Naturally, all kinds of mayhem ensues. The work-in-progress cut that screened at SXSW earlier this year was inconsistent, but funny enough to warrant a second round with the finished version. And yes, that cut did feature a scene where Keanu the kitten speaks with the voice of Keanu Reeves, but at the time, it wasn't clear if it was the man himself or a skilled imitator.
Speaking with the LA Times, director Peter Atencio explained that he initially reached out to Reeves' representatives, but he didn't get very far. However, the arrival of the film's trailer changed everything:
Yeah, they politely declined. Who knows if he ever even heard about the offer. But then we got a call after the trailer came out — apparently, his sister showed him the trailer and said, 'Hey, you gotta see this. You're gonna love this!' He flipped out and got in touch with us directly to say 'If there's anything I can do, let's make this work.'
Before he signed on, Reeves wanted to speak with Atencio to make sure the movie wasn't making fun of him. Atencio has nothing but nice things to say about his conversation with the man who gave his movie its title:
He wanted to talk to me before he agreed to make sure that wasn't the case. So I told him about the movie and talked him through the story. His personality has just transcended life, in a lot of ways. You wouldn't have ever guessed that the guy from Bill and Ted's Excellent Adventure would turn out to be this thoughtful, kind man.
So Reeves recorded his cameo in Rome, where he was filming John Wick: Chapter 2 and the rest is history. You can watch Keanu Reeves play Keanu in Keanu when the movie hits theaters this Friday.
The post Yes, Keanu Reeves Voices Keanu the Cat in 'Keanu' appeared first on /Film.
UPDATE: Page Six has learned that Reagan is no longer on Will Ferrell's docket, and there's a chance it may never have been. A representative told Page Six, "The 'Reagan' script is one of a number of scripts that had been submitted to Will Ferrell which he had considered. While it is by no means [an] 'Alzheimer's comedy' as has been suggested, Mr. Ferrell is not pursuing this project."
It's not clear if Ferrell was possibly involved and some outcry about the project changed his mind, but either way, he's not starring in the movie, nor is he producing it. So the project will have to find some other talent to bring it to life, if anyone else out there dares to make it happen. Our original story from yesterday follows below
Will Ferrell is no stranger to political satire. The comedian garnered a huge following while on Saturday Night Live for his iconic portrayal of President George W. Bush, which he eventually reprised for a one-man stage show. Plus, he also starred in the comedy feature The Campaign, not to mention skewering cable news in Anchorman 2: The Legend Continues. Now Ferrell will bring another Republican president to life, this time on the big screen.
The Black List comedy script Reagan has just landed Will Ferrell to star as President Ronald Reagan. However, at least one member of the president's family is already unhappy with the project. Find out why below.
The movie that will have Will Ferrell playing Ronald Reagan takes place at the start of the ex-president's second term, when the Commander in Chief started to develop Alzheimer's disease. In the film, an intern is tasked with convincing Ronald Reagan that he's an actor playing the president in the movie. That sounds like a hilarious concept, which is probably why the script from Mike Rosolio made the Black List last year. But Ronald Reagan's son Michael Reagan doesn't agree. He took to Twitter to gripe about the comedy:
Alzheimers is not a comedy!Will Ferrell to play dementia-stricken Ronald Reagan https://t.co/5wdo2PVvHt via the @FoxNews Android app
— Michael Reagan (@ReaganWorld) April 27, 2016
What an Outrag….Alzheimers is not joke…It kills..You should be ashamed all of you. https://t.co/GNzqR5vjrX
— Michael Reagan (@ReaganWorld) April 27, 2016
One can't really slight Michael Reagan for being mad about a satire that aims to make jokes out of a debilitating disease that his father had. It's a tough ailment to deal with both for the one who has the disease and for their family. There have been plenty of other people echoing Reagan's sentiments regarding both the disrespect for Ronald Reagan and for Alzheimer's patients in general.
But this is satire we're talking about, and sometimes comedy is the best way to deal with painful subject matter. Personally, I don't find this comedic concept to be disrespectful of Ronald Reagan or Alzheimer's patients. It's a fabricated story that uses real-life tragedy as a jumping off point for comedy, and it's no more disrespectful than anything that was done on Saturday Night Live to mock Ronald Reagan, or any other president for that matter.
Plus, when you consider how much time has passed, it doesn't seem like all that insensitive of a comedic concept. Tragedy plus time equals comedy. Plenty of people make jokes about Abraham Lincoln or John F. Kennedy being assassinated, and one could argue that getting shot in the head is probably much worse than Alzheimer's disease.
Satire is often meant to be provocative, so this kind of controversy is nothing new. But since Variety says the movie doesn't have a distributor just yet, any potential outrage or adversity may stop the film from getting off the ground. The film doesn't have a director yet, but with Ferrell also producing through his Gary Sanchez Productions banner, they shouldn't have a problem finding one.
What do you think of this Ronald Reagan comedy?
The post Will Ferrell Not Starring in Presidential Comedy 'Reagan' After All [UPDATED] appeared first on /Film.
Filed under: News, UFC, Videos
Yair Rodriguez is known for being a bit of a walking highlight reel, but he outdid himself with a flying switch kick knockout of Andre Fili at UFC 197.
The featherweight bout opened up the main card of the UFC 197 event at MGM Grand Garden Arena in Las Vegas. It aired on pay-per-view following prelims on FOX Sports 1 and UFC Fight Pass.
Fili (15-4 MMA, 3-3 UFC) was on his toes from the first second with Rodriguez (7-1 MMA, 4-0 UFC) whipping flashy kicks at his legs, body and head. Making matters worse for the Team Alpha Male fighter was Rodriguez's ability to score takedowns and work from top position.
After managing to get the fight back to the feet, Fili found himself on the receiving end of a knockout that will become a staple of UFC advertising for years to come. Rodriguez launched himself into the air and landed a switch kick to the face of Fili, knocking him stiff and ending the bout at the 2:15 mark of Round 2.
Check out the video highlights above.
Also see:
For complete coverage of UFC 197, check out the UFC Events section of the site.
For #1
Crusoe the Celebrity Dachshund (previously at Neatorama) and his brother Oakley don ridiculous little uniforms to play a game of street hockey. They're not very good players, but no one cares because they are so funny!
These dogs have little trouble aiming their sticks, and tend to succumb to temptation and eat the puck. But you won't find better dachshund hockey players anywhere! -via Tastefully Offensive
meanwhile at the @nuggets v @spurs game pic.twitter.com/OvpvYeXY5P— rachael (@RachaelHoops) April 9, 2016
Kiss cams are old hat! Besides, it can be truly embarrassing when the camera focuses in and you're sitting there with your brother, or even worse, your side-dude. Last night, the Denver Nuggets hosted the San Antonio Spurs, and unveiled a new crowd-cam idea that everyone immediately understood and took to: The Lion King Cam!
During a timeout, the camera finds a baby in the crowd, focuses in, and plays the opening lines from "The Circle of Life." The object of the focus immediately understands what to do. All new parents, and even aunts and granddads, know they are supposed to hold the baby up just like Rafiki presenting Simba to the Pride Rock residents (or, for those of us of a certain age, the infancy of Kunta Kinte). We hope Denver keeps this idea going, and it may spread to other arenas. -via Uproxx
Love 2Cellos.
2CELLOS are back with a little number that blends Beethoven's Fifth Symphony with "Whole Lotta Love" from Led Zeppelin. By the time they are finished, it's four cellos.
Luka Sulic and Stjepan Hauser were once rivals for the title of hottest best cello player in Croatia, and then teamed up to form 2CELLOS. Which was a great move. Hear more of their music in previous posts at Neatorama.
-via Buzzfeed
That's fucked up.
...I'd try it.
The bad news is that Elliot was not able to rescue E.T. and ensure that he got back home.
The good news is that E.T. is delicious!
(Photos: Bengt Pettersson and Helga Steppan)
Eating E.T. is an occasional project by Terje Östling and Unsworn Industries, a design firm in Malmö, Sweden. They crafted an E.T. sculpture out of vegan-friendly foods and roasted it at the Exploring the Animal Turn symposium in Lund, Sweden in 2014. Later they made another E.T. and roasted him at the Foodycle festival in Helsinki, Finland.
The purpose of the project, beyond eating good barbecue, is to explore how being human impacts ethical food choices:
What would it feel like to eat an alien? How can we dearly love and grieve some non-human species while accepting the industrialised slaughter of others? How can we cater to the needs of eaters who seek a surrogate for the sacrificial and ritual aspects of convivial, meat-based, barbecues? What are our ethical responsibilities towards fictional organisms?
-via Nerdcore
Love these.
Octopuses1 are complicated creatures: vulnerable but strong; slimy, but also kitten-like. And they're full of remarkable secret powers.
(Image credit: Flickr user Aoife Cahill)
Aside from its beak and braincase, an octopus is entirely squishy, meaning that a 100-pound giant Pacific octopus can squeeze through a hole about the size of a cherry tomato. They can also undo latches, untie knots, and open locks, all of which makes them extremely difficult to keep in captivity. In his 1973 book Octopus and Squid: The Soft Intelligence, Jacques Cousteau tells this charming story: "Our friend Gilpatric ... brought an octopus home and put it in an aquarium, which he then covered with a heavy lid. A short time later, the aquarium was empty, and Gilpatric found the octopus going through his library, book by book, turning the pages with its arms."
Given their love of libraries, it's no surprise that octopuses are the smartest invertebrates. They can solve puzzles, recognize human faces, navigate mazes, and even open childproof Tylenol bottles. In the 1990s, biologist Roland Anderson gave plastic pill bottles to the octopuses in his lab. Once they learned the bottles weren't edible, all of the octopuses lost interest- except for one. A female octopus used her funnel2 to push the bottle to the opposite end of her tank. The water current pushed it back, and again, she pushed the bottle away. After repeating the move 18 times, Anderson had no doubt: The octopus was playing a game of bouncy ball.
Since they move around to find prey, an octopus must find a new home every few days. The ideal pad is hidden, dark, and just a little larger than the octopus's body, so octopuses will often hide in the crevice of a rock, an old seashell, the hull of a shipwreck, or a stubby brown bottle. ("If you're determined to litter at sea but still want to keep the little octopus in mind, I suppose Red Stripe bottles might be the way to go," writes Katherine Harmon Courage in her book, Octopus!) Once the octopus selects a house, it uses its funnel to blow debris out of the den, and then barricades the entrance with rocks to keep out unwanted visitors.
(Image credit: Sylke Rohrlach)
Octopuses are careful housekeepers and spend time each day cleaning the sand, gravel, and the remains of last night's dinner from their house. Divers have learned to spot octopus dens by looking for a trash pile just outside the entrance. Female octopuses are also skilled interior decorators: They lay their eggs in long strings and attach them to the ceiling like translucent beaded curtains.
(Image credit: Brocken Inaglory)
Some shallow-water species occasionally come ashore to hunt. Some have even been caught eating seagulls. But walking is just the beginning: To the chagrin of some scientists, these cephalopods can run. As a pre-veterinary student, Alexa Warburton had the tricky task of scooping octopuses out of their tanks. The stubborn animals would hide or squeeze into the tank's cracks to avoid being removed. As a last-ditch effort, some octopuses would trampoline off the net, leap to the floor, and take off zig-zagging around the lab. It's "like chasing a cat," Warburton told Orion magazine.
In less than 0.3 seconds, octopuses can change their color, texture, and shape to blend in with their surroundings—transforming their skin to mimic algae-covered rocks, a sandy seabed, or fronds of kelp. (Special cells let them display different pigments, while bumps on their skin called papillae can create textures.) It's astonishing, considering that scientists believe octopuses are colorblind. But that's just the first act: If a predator still isn't fooled, some species can deploy a pseudomorph—a life-size self-portrait made from a cloud of ink and mucus. The specter distracts and irritates the predator and allows the octopus to jet away.
The mimic octopus, a smaller species that lives in the Indo-Pacific, uses its shape-shifting skills for a mind-boggling defense. Instead of convincing would-be predators that it has disappeared, T. mimicus instantly changes shape to look and act like venomous creatures, including flatfish, spiky lionfish, jellyfish, and sea snakes.
Concerned for the octopus's safety, Seattle Aquarium staff were hesitant to house dogfish sharks and a giant Pacific octopus in the same tank in 2001. They did it anyway, and for a while, everything seemed calm. Then partially eaten sharks began turning up on the tank's floor. A video camera captured the perpetrator—the octopus—following unhealthy sharks around the tank, grabbing them, and chowing down. Octopuses will also rip the stinging tentacles off a Portuguese man-o'-war and wield them like a weapon.
(Image credit: Делфина)
Deep inside its rubbery mantle, an octopus has a sharp beak and a toothed, tongue-like ribbon called a radula. When its super-strong arms aren't enough to pry apart a tasty clam's shell, the octopus uses its radula to drill a small hole in the shell, then injects a neurotoxin into the opening. The clam goes limp, the shell opens, and lunch is served.
The couch potato of the sea, octopuses will go to great lengths to avoid leaving the house. Fortunately, the male's sex organ is at the end of one arm, so mating doesn't have to be intimate. While some opt for the traditional mounted technique, others prefer what scientists call the "distance position." Male and female Abdopus aculeatus adults will even find houses near one another so that the male only has to stretch his hectocotylus—or sex arm—out his front door and into the female's house. Everybody stays safe indoors, and nobody has to buy dinner.
1. It's true! The most acceptable English plural is octopuses, not octopi. The classic Latin plural -which adds the i- is great for Latin-based words. Problem is, octopus isn't Latin! It's Greek. Octopodes, the Greek form, is also acceptable but a little archaic.
2. The funnel is nature's great jet propulsion system, helping some octopuses dart through the water at 25 mph.
The above article is reprinted with permission from the May 2015 issue of mental_floss magazine.
Don't forget to feed your brain by subscribing to the magazine and visiting mental_floss' extremely entertaining website and blog today for more!
Dangerous Minds appropriately calls this outfit the "holy grail" of fashion. Fashion designers might as well pack it in because the long quest for the perfect, every day, all day outfit is now finally complete. Rage On sells an adult onesie covered with faces of actor Steve Buscemi's movie characters.
Minor problem: there's no flap in the back. You could probably cut one, though.
Vince Gilligan and Peter Gould like to include Easter Eggs in their shows for observant fans to find, and viewers enjoyed finding secret stuff on Breaking Bad so much Vince and Peter decided to keep the Eggs rolling in Better Call Saul. (Spoiler-ish material ahead)
For the second season of Saul they decided to go beyond the visual and play with words by including an anagram in the episode titles, so they put the puzzle in place and didn't give it a second thought.
But a fan named Shaquita discovered the Easter Egg faster than a tweeker on Blue Sky, posting her findings on Twitter with the caption "on vacation this week, and have nothing but time lol".
@BetterTalkSaul on vacation this week, and have nothing but time lol pic.twitter.com/KvHF8WY4JV— Shaquita (@sirena6783) March 28, 2016
The creators confirmed Shaquita's findings and were blown away by how fast she found it:
"We had this—to us—this very bright idea of encoding the words "Fring's Back" in the episode titles," Gould told Vanity Fair. "And we thought we'd be revealing it maybe sometime over the summer. I guess we really underestimated the genius and hard work of our fans."
"And their attention to detail, and God bless them for it," Gilligan chimed in.
Gould concluded: "It's hard to complain about people paying attention to every aspect of the show. It certainly reminds us again that we better keep all our i's dotted and our t's crossed in every aspect of the show."
-Via Independent
#bowie vs. #prince #ride #Pedalpalooza #pdx #pedalpalooza15 #Bowievsprince
A photo posted by julie b. (@julie_b_xyz) on Jun 26, 2015 at 8:39pm PDT
Every year since 2008, cyclists in Portland, Oregon, have taken part in a ride called Bowie vs. Prince. They sign up for either Team Bowie or Team Prince, and then dress like them for the ride. Founder Lillian Karabaic had considered changing the event in the wake of Bowie's death.
"Me and my co-leader, with Bowie's death this year, were considering making the ride Bowie vs. Bowie," said Karabaic. "We felt like a lot of people wouldn't want to be Prince in light of it. I guess for better or worse, it's now going to be Bowie vs. Prince again."
Karabaic was thinking about ending the annual ride even before the stars' deaths. She's hoping some other event can take its place next year, but thinks it's fitting this year's bike ride will be the last.
"Bowie vs. Prince is going to be a totally different type of ride this year," she said. "It's going to be a memorial ride."
Somehow, I think that this year's event may be the biggest of all, even if it is the last one. -via Uproxx
City Council approves "out of scope" changes to Trader Joe's While most "small" businesses in Hoboken get jerked around (often times to the tune of 6 to 12 months of costly – and unjustifiable...
The post Trader Joe's Hoboken appeared first on Hoboken411.com.
This is awesome.
It sounds like a headline out of Warren Ellis's Iron Man run.
Isaac Perlmutter, the billionaire CEO of Marvel and one of Disney's largest shareholders has, along with his wife Laura Perlmutter, donated an additional $9 million to the NYU Langone Medical Center and the Technion-Israel Institute of Technology in addition to a 2014 donation of $50 million that set up the Perlmutter Cancer Center.
The first $3 million of that will be used to finance six joint research projects, with co-investigators on each project will receive a two-year, $500,000 grant–$250,000 for each site.
While the remaining $6 million will establish a state-of-the-art research facility on the Technion campus in Israel to support these and other research projects, primarily in the emerging field of cancer metabolomics, the systematic study of the unique chemical fingerprints that cellular processes leave behind. These processes are both affected by, and can influence, a variety of human diseases, including cancer.
In the first joint collaboration, NYU Langone and Technion researchers will test the ability of a nanotechnology based on stem cell "nanoghosts" to deliver to the brain a promising treatment for metastatic melanoma, skin cancer that has spread or metastasized, and is often incurable.
In earlier studies, researchers at the Technion took a stem cell, removed its contents, and then shaped a piece of the cell's outer membrane into a vehicle to deliver treatments into the brain. The idea was to borrow the stem cell's outer membrane ability to home in on cancer cells. As a fragment of the former stem cell's membrane, the nanoghost encompasses particular mechanisms that slow it enough to traverse the barrier that filters blood flowing into the brain, and which keeps most drugs from entering.
The nanoghost's cargo is a microRNA (miR), a stretch of genetic material that fine-tunes genetic messages by blocking the conversion of genes into proteins. First applied by NYU researchers to metastatic melanoma, miR-124a, in particular, blocks the expression of cancer-promoting genes. The joint team's experiments will seek to determine the feasibility of encapsulating miR-124a in the nanoghost, and study how the vehicle reaches its target in mouse models of the disease.
"Our studies should provide important information on nanoghosts' general value as drug and gene carriers to the brain, and create potential for new treatment approaches against brain tumors and metastases," said Professor Marcelle Machluf, PhD, head of the Laboratory for Cancer Drug Delivery & Cell Based Technologies at the Technion, and inventor of the nanoghost with her colleagues there. "The difficulty of delivering agents to the brain represents a major impediment to improving outcomes in patients suffering from brain tumors. Our state-of-the-art nanovehicle promises safer, simpler and more clinically relevant treatments than existing vehicles, which are comprised of polymers or synthetic vesicles which largely lack the ability to enter the brain and to target evolving and changing pathologies."
"It is much harder to secure funding for this type of high risk, high reward research," said Eva Hernando-Monge, PhD, associate professor in the Department of Pathology at NYU Langone, a member of the Perlmutter Cancer Center, and leader of the NYU team that first identified miR-124 as a suppressor of the growth of brain metastases. "The Perlmutters' generous gift gives us the ability to be bold."
Like the stem cells they are based on, nanoghosts are invisible to the immune system, which means they could potentially be made from donated stem cells, expanded to large numbers in the lab, and not just from the patient's own supply. In the future, this could enable the stockpiling of nanoghost treatments used off the shelf without fear of immune reactions to treatments based on "foreign" cells.
The second joint project will investigate whether an enzyme called heparanase can be used to diagnose and treat mesothelioma, a rare cancer that develops in the mesothelium, the protective lining of the lungs and other internal organs of the body. Malignant pleural mesothelioma (MPM), the most common form of the disease, often occurs after exposure to asbestos and is resistant to most therapies.
Heparanase was first identified as a treatment target in 2004 by a team led by Israel Vlodavsky, PhD, one of the project's co-investigators and professor at the Rappaport Faculty of Medicine. Past studies found that patients with high levels of this enzyme in their tumors have lower survival rates after surgery, and that related tumors in mice respond to treatment with heparanase-inhibiting compounds.
The enzyme breaks up molecular chains of heparan sulfate, a building block of the scaffolds that give organs shape and support. Cancer cells use the enzyme to break down tissue barriers around a growing tumor, providing new pathways for the cancer to spread and for the building of blood vessels that supply tumors. In addition, breaking up extracellular matrices releases pro-growth proteins stored there to further drive disease. Furthermore, the joint team has developed the novel theory that heparanase secreted by tumor cells primes local microenvironments in a "vicious" cycle where inflammation and tumor growth drive each other.
The co-investigators at NYU Langone — led by Harvey I. Pass, MD, the Stephen E. Banner Professor of Thoracic Surgery and vice chair for research, Department of Cardiothoracic Surgery, at NYU Langone, also a member of its Perlmutter Cancer Center — will use tissue samples from its Thoracic Oncology Archives to validate Dr. Vlodavsky's findings in hopes of eventually evaluating the treatment potential of heparanase-inhibiting compounds in mesothelioma clinical trials. Dr. Pass has been collecting tissue samples from his surgical patients since 1989, when he was head of thoracic oncology at the National Cancer Institute (NCI). The collection now houses frozen specimens from more than 350 mesothelioma patients.
"This project, supported through the generosity of the Perlmutters, enables us to collaborate with one of the world's leading experts on the role of heparanase in cancer, and is crucial in developing new strategies," Dr. Pass says. "We hope that these experiments can be translated into applications for ongoing funding from the NCI, and enable Phase I trials with new therapeutics that influence heparanase pathways."
"Our collaboration represents the first attempt to focus on heparanase as a major risk factor in mesothelioma and a valid target for the development of heparanase-inhibiting drugs," Dr. Vlodavsky says. "In fact, applying a potent inhibitor of the heparanase enzyme we have already demonstrated a most prominent inhibition of tumor progression in mouse models of human mesothelioma, resulting in a pronounced extension of mouse survival. This joint effort provides an opportunity to make important strides in both our fundamental understanding of mesothelioma and in translating this knowledge into therapeutics."
Much has been made of the Perlmutter's financial support for the Republican Party Presidential candidates with two million to promote Marco Rubio's Presidential campaign, and one million to Donald Trump's veteran campaign. Rubio has stated that he does not support human embryonic stem cell research while Trump stated he is undecided. Technion however was the place that first harvested human embryonic stem cells and are likely to form the basis for this research. It may demonstrates that the Perlmutter are a little more nuanced when it comes to putting their money where their mouths are.
Marvel's Ike Perlmutter's Millions To Fund Nanoghost Technology


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Have you ever helped your child with a school assignment?
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text:
|Publication number
|Publication type
|Application number
|Publication date
|Mar 21, 1995
|Filing date
|Apr 2, 1993
|Priority date
|Apr 2, 1993
|Fee status
|Publication number
|Christian L. Trudeau
|Original Assignee
|Simmonds Precision Products, Inc.
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (13), Referenced by (32), Classifications (10), Legal Events (5)
|External Links: USPTO, USPTO Assignment, Espacenet
The invention relates generally to fuel gauging systems for fuel tanks. More specifically, the invention relates to fuel gauging systems that use ultrasonic level sensors particularly suited for fuel tanks on aircraft.
Ultrasonic fuel level sensors for detecting surface levels of fuel in a tank are well known. These sensors operate using echo ranging in which an ultrasonic pulse on the order of 1 megahertz is emitted towards the liquid surface. The ultrasonic pulse is reflected at the fuel/air interface and returns towards the sensor in the form of an echo pulse. This echo pulse is then detected by the same or a different sensor. The detection sensor typically produces an output signal that corresponds to receipt of the echo. Thus, the round trip time from pulse emission to echo detection corresponds to the distance of the liquid surface from the sensors.
Aircraft fuel gauging systems usually require a large number of such fuel sensors in each tank based on the tank size, location, configuration, degree of accuracy required and possibly for safety redundancy. It is not unusual for a fuel tank to contain 10 or 20 such sensors. Not surprisingly, as the number of ultrasonic sensors increases, so does the complexity of control mechanisms used to interrogate the sensors. Therefore, ultrasonic fuel gauging apparatus commonly have depended on the use of microprocessor controllers and their attendant overhead software programming. However, such dedicated microprocessor based systems can either he expensive to design and maintain, or require complicated interface circuitry to a more powerful system controller. Software errors can also either lower reliability or become costly to locate and remove as system complexity and size increases.
There is a need, therefore, for a lower cost, simpler design for an ultrasonic fuel gauging system that can control a multisensor system without the need for a microprocessor and its attendant software.
In response to this need, the present invention contemplates an ultrasonic fuel gauging apparatus and methods embodied in the use of such apparatus for a fuel tank, wherein the ultrasonic fuel gauging apparatus comprises a plurality of ultrasonic fuel level sensor means for sensing fuel levels at respective predetermined locations in a tank based on echo ranging; memory means for storing control parameters and sensor data; and a state device for interrogating each of the sensors by controlling the application of transmit pulses to each of the sensors and for receiving output signals corresponding to return echoes, the state device operating in response to a sequential state counter.
FIG. 1 is a system functional block diagram of a preferred fuel gauging apparatus according to the present invention;
FIG. 2 is a preferred system state diagram for the apparatus of FIG. 1; and
FIG. 3 is a more detailed preferred state diagram for the apparatus of FIG. 1.
With reference to FIG. 1, a preferred fuel gauging apparatus according to the present invention is generally designated with the numeral 10. This apparatus is particularly well suited for fuel gauging systems used for fuel level detection and gauging in aircraft fuel tanks. An important feature of this embodiment is the use of a state device 12, which I refer to herein as a state device or state machine. The state machine 12 in the preferred embodiment is constructed using a configurable logic device such as part number EPM 7256WM available from ALTERA. However, the term "configurable" with respect to the device 12, is not a reference to software configurable, and in fact an important aspect and advantage of my invention is that the apparatus 10 operates without the use of overhead software commonly associated with microprocessor controllers. Rather, by "configurable" herein I mean that the state device as provided by the manufacturer as simply an array of logic gates and circuits that are not configured to perform a particular dedicated function. Instead, the functions and interconnections of the electronic gates and circuits in the configurable logic device are user defined, so that their operation is that of a state machine which can be sequentially controlled by a simple clock counter. The hardware components are configured as needed to form a state machine to operate simply in response to a clock. Thus, the device 12 operates in the nature of a state machine, in which one or more functions are executed depending on the state count of the device 12. For example, a state machine model can be represented by a finite set of states and state transitions which take place by occurrence of events, e.g., in the form of input signals and prescribed conditions. In a finite state machine model, when a state transition takes place by occurrence of an event, a particular action or operation in response to an input signal takes place. Furthermore, the state device 12 can be reconfigured as needed. In any event, the fuel gauging apparatus 10 is fully operational without attendant software or firmware, such as firmware stored in a ROM.
The state machine 12 as shown in FIG. 1 is connected to a plurality of ultrasonic fuel sensors, represented schematically as block 14, which would be physically located in a fuel tank. In FIG. 1 the sensors 14 are simply represented by a functional block because the sensors are all accessible to the fuel gauging apparatus 10 by appropriate wire connections. The sensors 14, of course, are distributed throughout the fuel tank in a predetermined manner so as to maximize the accuracy of the fuel measurement, as is well known in the art. In the embodiment of FIG. 1, there are provided twenty-four (24) sensors. The state machine 12 accesses each sensor through a multiplexed transmit bus 16 and a multiplexed echo receive bus 18. The state machine 12 also controls gain, burst duration and echo threshold signals 20, 22 and 24 respectively for each sensor.
The state machine 12 is further connected to a random access memory (RAM) device 26 that is used by the state machine 12 during data acquisition to store echo data for each of the sensors 14. The state machine 12 can address the RAM via an address bus 28, and uses signal DATA bus 30 to send and receive data from the RAM 26.
The state machine 12 is also connected to one or more storage registers 32, which are used as a memory to store control parameters such as the echo burst duration, gain values for setting acoustic pulse transmit energy, and threshold values used to detect valid echo returns. Other control parameters can of course be stored in the registers 32, such registers preferably being nonvolatile.
Furthermore, the state machine 12 is operatively connected to a series of counters including an echo counter circuit 40, an measurement counter 42, a sensor counter 44 and a sample counter 46. The echo counter circuit 40 is enabled by the state machine 12 via an ENABLE signal on line 48 and sends echo data to the state machine on data bus 50 in the form of a count which represents the time elapsed between an ultrasonic pulse being transmitted from a particular sensor and the resultant echo being received. The configuration of the state machine 12 controls which sensor 14 echo returns are received from and in which order by sequencing of the multiplexed echo receive bus 18 one sensor at a time. The order in which the sensors are processed is predetermined and designed in as part of the state machine 12 configuration. For example, the order may start with a sensor nominally identified number one being interrogated and sequentially interrogating the remaining sensors through to a sensor nominally identified number twenty-four.
The measurement counter 42 is used by the state machine 12 to identify the maximum time window during which a valid echo can be detected. The state machine 12 uses START and STOP control signals on lines 52,54 to control the measurement counter 42. The count values are returned to the state machine 12 via a MEASUREMENT COUNT signal on bus 56. The count value of the measurement counter 42 represents the elapsed time following emission of an ultrasonic pulse from the sensor 14 presently being interrogated.
The sensor counter 44 is used to identify which sensor 14 is to be interrogated at any given time of operation, e.g., the sensor counter 44 will have a value from 1 to 24 corresponding to the nominal value associated with the respective sensor 14. After all sensors have been interrogated, the state machine 12 issues a CLEAR counter command on line 58 to reset the sensor counter 44. The sensor count data representing the active or presently interrogated sensor 14 is sent from the counter 44 to the state machine 12 via a SENSOR COUNT signal on bus 60.
The sample counter 46 is used to keep track of how many interrogation passes have been made to each sensor 14, since multiple attempts to receive or validate echo returns may be tried. In other words, preferably the state machine 12 interrogates all 24 sensors sequentially, then repeats this interrogation in additional passes for a predetermined number of times, such as eight. Thus, the state machine 12 "loops" through all the sensors 14 a total of eight times and can store all the echo data for each sensor 14 in the RAM. (e.g., at 24 sensors and 8 samples per sensor there could be up to 192 echo data samples to store in the RAM). The count data is provided to the state machine 12 via the SAMPLE COUNT signal on bus 62, and the sample counter 46 is reset by the state machine 12 using the SAMPLE CLEAR signal via line 64.
A master clock signal provided on line 70 from a clock circuit 72 is used to activate and count the state machine 12 through its respective states and numerous functions. A series of shift registers and other timing devices internal to the state machine respond to the clock to sequentially control the various functions of the state machine. In the exemplary embodiment, the master clock signal 70 may be a 16 MHz oscillator which is divided down via counters or the like to a 500 kHz state clock to drive the state machine 12 through the described states at 2 microsecond intervals.
Operation of the fuel gauging apparatus of FIG. 1 is as follows. The clock circuit 72 applies clock pulses to the state machine 12 at power on. The state machine 12 automatically resets to an initial state (state SA in FIG. 2) and begins sequentially to interrogate each fuel level sensor 14. For each sensor 14 the state machine 12 issues an ultrasonic transmit pulse via the multiplexed transmit bus 16 to the active sensor 14 and uses the echo counter 40 to measure the time lapse for a valid echo to return. Transmit pulse energy can be set by a value stored in the register 32. When valid echos are returned via the multiplexed echo receive bus 18 (wherein a valid echo can be, for example, an echo detected within a valid time window determined by the measurement counter 42 and having a minimum energy level set by a threshold value stored in the register 32), the state machine 12 stores the corresponding data in the RAM 26 at a specific memory location for each sensor 14. After all the sensors 14 have been interrogated, the state machine 12 interrogates them all again and again until the sample counter 46 reaches the preset limit for the number of passes to be taken. The sensor counter 44 provides control to the state machine 12 to indicate which sensor 14 is the current sensor to interrogate. When all sensors have been interrogated the state machine 12 resets the sensor counter 44 via a reset control signal (not shown).
Thus, a hardware-only ultrasonic sensor data acquisition apparatus is provided that can interrogate a plurality of sensors without the use of a microprocessor or its attendant software.
With reference next to FIG. 2, I show an exemplary system state diagram for the preferred embodiment of my invention as illustrated in FIG. 1. Upon power up of the fuel gauging apparatus, the state machine 12 is initially in state SA. In state SA, the state machine 12 automatically resets the sensor and sample counters 44,46. If a START CYCLE signal provided to the state machine 12 from an external source is low or "0", indicating that the fuel gauging apparatus is to remain in an idle mode, the state machine remains in state SA. When the START CYCLE signal goes to 1, indicating that it is desired that the fuel gauging apparatus begin to cycle through the sensors 14, the state machine 14 proceeds to state SB. In state SB the sensor counter 44 sets to 1, representing the first sensor 14 to be interrogated. This control action also sets the multiplexed address via lines 16 and 18 for the correct sensor 14 and the RAM address via address bus 28 for storing the echo data in the corresponding RAM memory location for the first sensor.
If the state machine 12 is at the first interrogation for the first sensor 14 (identified by the output of the sample counter 46 being equal to zero), then the state machine 12 transitions at 100 to state Sc whereat it stores in the RAM 26 the sensor parameters accessed from the registers 32 (note that the registers 32 can store different control values for each sensor, with the state machine 12 accessing the appropriate data using the sensor parameter lines 72'). The state machine 12 then advances to state SE and the first current sensor 14 is interrogated and the echo data is stored in the RAM 26. In state SE, if the sensor count from the sensor counter 44 is less than twenty-four, indicating that not all sensors 14 have been interrogated yet in the present cycle, the state machine 12 transitions at 102 to state SF where the sensor counter 44 is incremented by one and the state machine 12 returns to state Sc. It is noted that during the first interrogation cycle when the sample counter 46 output is still zero, the state machine 12 transitions from state SF directly to state Sc via branch 104 because until the first interrogation sequence is completed for all the sensors 14, the state machine 14 must initialize the sensor parameters into the RAM. The above-described interrogation sequence then continues for each sensor 14 until all twenty-four sensors have been interrogated. (Note that during the first pass thru each of the sensors the sensor parameters are initialized for each sensor at state SC).
In state SE, the state machine 12 checks the output of the sensor counter 44, and when the output of the sensor counter 44 equals the total number of sensors (in this exemplary description it being twenty-four sensors); then, if the sample counter 46 output is still less than eight, the system branches at 106 back to state SB, increments the sample counter, and interrogates all the sensors again. Note however, that after the first interrogation pass (during which sample counter ≠0), the state machine 12 advances at transition path 108 from state SB to state SD because the sensor parameters have already been accessed initially, stored, and do not need to be initialized again. All the sensors 14 are thus interrogated again and again until the sample counter output reaches the preset limit (in this example seven) for the number of samples per sensor to be acquired. Note further that in state SF, if the sample counter ≠0, the system branches via transition path 110 directly to state SD and recalls from the RAM 26 the appropriate sensor parameter data for the current sensor 14 being interrogated.
In state SE, when the output of the sample counter 46 equals the total number of samples per sensor and when the sensor counter 44 has reached the total number of sensors (i.e., twenty-four) for the eighth time, the state machine transitions via path 112 from state SE back to state SA and again resets and starts the entire start cycle over again in the event the start cycle signal is active.
The state diagram of FIG. 2 is now described in greater detail with reference to FIG. 3 and the accompanying Table I, which illustrate and describe in detail the various sequences between states SA through SF shown in FIG. 2. The states SA thru SF in FIG. 2 are represented in FIG. 3 by one or more individual states, i.e., substates, as will be appreciated. State SA of FIG. 2 is represented by state S0 in FIG. 3 in which the state machine 12 is reset upon power up. In addition, the sample and sensor counters 46, 44 are cleared and the various outputs are initialized in state So as represented in Table I. State SB of FIG. 2 is represented by state S1 in FIG. 3 in which the sensor counter is set to 1. State SC of FIG. 2 is represented by states S1, S2, S3, S4, S5, S6, S8, S9 and S10 in FIG. 3, the functions of which are to set default values for gain, burst and threshold of echo signals to be detected on lines 20, 22 and 24, respectively (State S2); clear the measurement counter 42 to zero, and output values for gain, burst and threshold on lines 20, 22, and 24, respectively (S3); initiate transmission of an ultrasonic pulse (S4); set the burst value on line 22 to a maximum value (S6); increment the gain value on line 20 (S8), set the burst level on line 22 to a maximum value, and the threshold on line 24 to its low value (S9), and set the burst level to a minimum value (S10). State SD of FIG. 2 represents states S3, S4, S5, S6, S8, S9 and S10 in FIG. 3. State SE of FIG. 2 includes states S7, S13, S14 and S12 of FIG. 3 during which the echo count data from each sensor is written to the RAM 26 until the maximum sensor count is reached. In state S7 the state machine 12 effects a write of the echo counter 40 output data to the RAM, and increments the sample counter 46 if the sample counter output is less than the maximum (e.g., eight). State S12 involves writing a stop bit to the RAM 26, and states S13 and S14 involve providing the appropriate write select and chip select instructions to the RAM 26 as part of the write operation effected in state S7. State SF of FIG. 2 corresponds to state S11 of FIG. 3 which increments the sensor count by 1 until the sample count equals zero.
In state SO the state machine 12 resets itself and waits for a start cycle signal indicating that the sensors are to be interrogated. In state S1 the sensor counter 44 is reset to 1, thereby identifying the first sensor 14 to be interrogated. Initially when the sample counter 46 is equal to zero, the state machine 12 transitions from state Sl to state S2. In state S2 the default values for gain, burst and threshold are set. The state machine 12 then proceeds to state S3 where the measurement counter 42 is reset and the values for burst, gain and threshold are output for the sensor being interrogated.
In state S4 the state machine 12 initiates the transmission of an ultrasonic pulse from the sensor being interrogated. The state machine continues in a closed self-loop in state S4 after the ultrasonic pulse has been transmitted until the output of the measurement counter 42 is indicative of a fixed time period (e.g., 3 milliseconds (msec)) having elapsed, during which an echo must be received in order to be considered valid. When the measurement counter 42 output represents 3 msec (the respective counters described, herein being incremented at a known frequency), the state machine 12 transitions to state S5.
In state S5, the state machine 12 evaluates the integrity of the return echo. If the sample counter 46 output is zero, indicating the first pass through the sensors 14, the state machine 12 transitions to either state S7, S6, S8 or S10. Which particular state is transitioned to from state S5 depends on the value of the echo counter 40 which represents the time elapsed between the transmission of the ultrasonic pulse in state S4 and the time which an echo is received. If the value of the echo counter 40 represents too short a duration, e.g., an elapsed time in which a return echo could not reasonably be expected so soon, in the present example less than 40 microseconds, the state machine 12 transitions to state S10 where the burst duration for the active sensor 14 is set to a minimum. The state machine 12 then returns to state S3 and then state S4 where the ultrasonic pulse is transmitted with a minimum burst duration.
If the value of the echo counter 40 represents an elapsed time between the transmission and receipt of the reflected pulse which is greater than or equal to 40 microseconds and less than a maximum time within which it is reasonably expected that the echo would be received, e.g., 640 microseconds, the received echo is considered to be valid. As a result, the state machine 12 transitions to state S7 where the echo data received on line 18 is written to the RAM 26.
If in state S5 the sample counter 46 is zero and the echo counter represents a time which is greater than or equal to 640 microseconds and less than a prescribed time within the 3 millisecond time period imposed in state S4, e.g., 2.75 milliseconds, the state machine 12 transitions to state S6. In state S6, the burst duration of the ultrasonic pulse for the current sensor 14 being interrogated is set to a predetermined maximum value. The state machine 12 then transitions to state S7 where the received echo count data is written to the RAM 26. If in state S5 the echo counter 40 is greater than 2.75 milliseconds, it is assumed that a valid echo has not been detected and the state machine 12 transitions to state S8. In state S8 the gain of the present sensor 14 is incremented via line 20 so as to increase the sensitivity of the sensor 14. If the gain of the sensor 14 is not at a predetermined maximum after being incremented, the state machine 12 transitions to states S3 and S4 and the above-described steps are repeated. If in state S8 the gain of the sensor 14 is incremented to the predetermined maximum, the burst level is not at a predetermined maximum, and the threshold level of the sensor 14 is not at a predetermined minimum (or low) as set in state S9, for example, the state machine 12 proceeds to state S9. In state S9, the burst duration for the particular sensor 14 is set to the predetermined maximum and the threshold to a predetermined low. The state machine 12 then transitions back to states S3 and S4 where the process is repeated. If in state S8 the corresponding gain and burst values of the sensor 14 are already at a maximum and the corresponding threshold level is at the predetermined minimum, the echo data is considered to be as best as can be expected. The state machine 12 transitions to state S7 where the echo count data is written to the RAM 26.
In state S7, the state machine 12 determines whether the output of the sensor counter 44 is at a maximum (e.g., 24) indicating that all sensors 14 have been interrogated in the present pass. Also, the state machine 12 checks whether the sample count is less than the predetermined maximum (e.g., 8) representing that the desired number of passes have been completed. If both conditions are satisfied, the state machine 12 increments the sample counter 46.and proceeds to state S13. Otherwise, the sample counter 46 is not incremented and the state machine 12 simply proceeds to state S13. It will be noted that after an initial pass through each of the sensors 14 the output of the sample counter 46 will no longer be equal to zero. Thus, the state machine 12 will transition from state S5 directly to state S7 at which point the respective values of burst, gain and threshold for the corresponding sensors 14 as established in the initial pass (as described above) and which were stored in the registers 32 are used. Also, when the output of the sample counter 46 is no longer equal to zero, the state machine will transition directly from state S1 to state S3 as shown in FIG. 3. This eliminates the step in state S2 where the state machine 12 sets the values for gain, burst and threshold to the default levels as is done in the initial pass.
Referring again to states S13 and S14, in these states the various operations completing the write operation of state S7 are performed, e.g., sending the appropriate write select and chip select signals to the RAM 26. In state S14, if the sensor counter 44 is less than the maximum, the state machine 12 transitions to state S11 where the sensor counter 44 is incremented to identify the next sensor 14 to be interrogated. If in state S11 the value of the sample counter 46 is equal to zero indicating the initial pass, the state machine 12 transitions to state S2 where the default values are set for the next sensor 14. If in state S11 the sample counter 46 output is not equal to zero indicating that the initial pass through all the sensors 14 has been completed, the state machine 12 transitions to state S3.
If in state S14 the sensor counter 44 output is equal to the maximum indicating the completion of a pass, but the sample counter 46 is less than the maximum indicating that these are more passes in the cycle, the state machine 12 transitions to state S1 where the sensor counter is set to one and another pass begins. If in state S14 the outputs of the sensor counter 44 and sample counter 46 are at the maximum, indicating the completion of a complete cycle, the state machine 12 transitions to state S12. In state S12, a stop bit is written to the RAM 26 to facilitate analysis of the echo count data stored in the RAM 26 using known techniques. From state S12 the state machine 12 transitions to state S0 whereat the above-process can be repeated for the next cycle when desired.
The state machine 12, as will be appreciated, can be made up of a large number of combinational (AND, OR, etc.) logic and sequential logic circuits (e.g. flip-flops) all within a configurable logic array such as the MAX EPLD (Erasable Programmable Logic Device) family manufactured by ALTERA.
The invention, therefore, provides a low cost design and hardware-only based apparatus for interrogating a plurality of ultrasonic sensors without microprocessors and software. Of course, the invention should not be construed in a limiting sense by the particular features of the described embodiment. For example, the invention can be used with any number of sensors and the number of interrogation cycles is largely a matter of design choice. Also, the invention is not intended to be limited to a state machine having a state diagram identical to those shown in FIGS. 2 and 3; rather, the state machine 12 can have any desired state design.
While the invention has been shown and described with respect to specific embodiments thereof, this is for the purpose of illustration rather than limitation, and other variations and modification of the specific embodiments herein shown and described will be apparent to those skilled in the art within the intended spirit and scope of the invention as set forth in the appended claims.
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|U.S. Classification
|International Classification
|Cooperative Classification
|European Classification
|Jul 30, 1993
Owner name: SIMMONDS PRECISION PRODUCTS, INC., OHIO
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:TRUDEAU, CHRISTIAN LOUIS;REEL/FRAME:006612/0739
Effective date: 19930326
|Jun 30, 1998
|Fee payment
Year of fee payment: 4
|Sep 20, 2002
|Fee payment
Year of fee payment: 8
|Oct 9, 2002
|Maintenance fee reminder mailed
|Sep 21, 2006
|Fee payment
Year of fee payment: 12


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Pak, India Must Make Efforts to Steer Talks: Zardari
31.08.2012 [Outlook] - Foreign Minister Khar, Interior Minister Rehman Malik, Pakistan People's Party chairman Bilawal Bhutto Zardari, Indian External Affairs Minister S M Krishna, India's Foreign Secretary and National Security Adviser were present during the meeting
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Bilawal Bhutto Family Festival, Bilawal Bhutto Zardari Park, Near Bhurgrri Pul, Khairpur, Khairpur Mirs, Pakistan. Fri Feb 26 2016 at 04:00 am, Bilawal Bhutto …
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25.05.2012 [Sydney Morning Herald] - The son of the president, and chairman of the ruling Pakistan Peoples Party, Bilawal Bhutto Zardari, said Afridi's sentence was justified. ''It is against the law in any country to co-operate with foreign intelligence … We have an independent
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Dear Mr Bilawal Bhutto zardari sahib Nice ti see you , her , Dear Iam Advcate Imtiaz Ali abbasi , From Sindh Iwrote a book On Father when he is in the Jell , Named ...
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Bilawal Bhutto Zardari the chairman of Pakistan people's party was taking up the post after death of his mother and party leader Benazir Bhutto. He is the eldest ...
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1 December 2011: A portrait of Scotland: Gallery reopens after £17.6 million renovation; 10 October 2011: Pakistani journalist found dead in home
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Daily English news paper Pakistan,Islamabad,Lahore,Karachi,Peshawar,Quetta,Sindh,Punjab,Bal…stan,Waziristan,Khyber,Mohmand,Kurram,Bajaur,Fata,Tribal...
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Bilawal Bhutto Zardari ist ein pakistanischer Politiker. Er ist der einzige Sohn der früheren Premierministerin von Pakistan Benazir Bhutto und des Politiker...
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Will mere condolences heal the wounds of heirs?
13.09.2012 [The Nation] - Pakistan Peoples Party Chairman Bilawal Bhutto Zardari has expressed shock and grief over the death of a number of innocent persons due to unfortunate incident of fire in a garment factory in Karachi. In a statement issued here, the Chairman PPP
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12.09.2012 [Associated Press of Pakistan] - TIANJIN, China, Sept 12 (APP): Prime Minister Raja Pervez Ashraf on Wednesday called upon the regional countries to adopt an Asia-centered approach and promote intra-regional trade for the prosperity and development of their people. Speaking at
Google News: Bilawal Bhutto grieved over loss of lives in fire incident at Karachi
12.09.2012 [Associated Press of Pakistan] - ISLAMABAD, Sep 12 (APP): Chairman Pakistan Peoples Party Bilawal Bhutto Zardari has expressed shock and grief over the death of a number of innocent persons due to unfortunate incident of fire in a garment factory in Karachi. In a statement issued here
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11.09.2012 [The Nation] - ... their daughter Benazir Bhutto, her husband Asif Ali Zardari (current president of Pakistan), and their 25-year-old son Bilawal Bhutto Zardari (president of the People's Party); the Nehru-Gandhis (no relation to the apostle of non-violence, Mahatma
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30.07.2012 Chairman Pakistan Peoples Party Bilawal Bhutto Zardari With Mohtarma Sanam Bhutto Bakhtawar Bhutto Zardari and... http://t.co/1UB5vfVF
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Boomer Esiason & Frank Deford on Real Sports
Learn more about the good fight against cystic fibrosis and the inspiring bond Frank Deford and Boomer Esiason share as fathers on the Jan. 21, 2014 episode of HBO's "Real Sports."
Newsday.com now uses Facebook for our comment boards. Please read our guidelines and connect your Facebook account to comment.
From LI to the NFL: The Victor Ochi story Canelo Alvarez kicks off fight week Amir Khan arrives in Vegas for fight Islanders lose heartbreaker in OT in Game 3 Capuano: Boyle is 'probably going to get suspended' Brazil ignites Olympic torch Wantagh players talk about 5-4 win over Division Study tracks football concussions, resuming play LI's top blue chip prospects compete in combine Isles looking to take advantage of home ice in Game 3 Prince Harry, Trudeau oromote Invictus games Cosmos vs. RailHawks highlights


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Ducks' star snaps photos at Olympics
Give a Duck a camera and what do you get? An inside look at the Olympics, that's what.
The Register gave Ducks defenseman Ryan Whitney a camera to get his view of the sights around Vancouver's Olympic Village.
Click on the PHOTO see what turned up.
CLICK HERE for a photo slide show of the United States-Norway game.
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Dalley is a retired all around horse. Did roping, barrels and poles. She is 18 years old and would be great for trail rides. Sweet quiet horse. Gets along…$2,000
Between her 10+ movement, and sweet personality, Rosie is sure to make a spectacular all around trail, and fun horse! She was started on trails as a youngster…$3,000
Sensible, experienced hunter/jumper, pre lim eventer. 4H prospect Bold over fences. Quiet and sensible. Loads, ties, baths, good for the farrier. Easy…$2,200
Petey is a 7-year-old 15h purebred Arabian gelding. He is an amazing trail horse and has been ridden in many of the local Pennsylvania state parks. He…$900
For a Full Gallery visit www.facebook.com/reeleert For Video see: https://www.youtube.com/watch?v=rZMdO21D8d4 https://www.youtube.com/watch?v=pbBEvf6…$2,500
Kate is a beautiful Draft-Cross mare. Sired by Harry the Hat (JC) out of a Clydesdale mare. She is extremely versatile in addition to being the "barn favorite…$9,500
"COOPER" is a 6yo chestnut throughbred gelding by Two Punch. OTT but was too slow. Has show experience as a hunter but would also do well in the jumpers…$8,500
Tall, dark and handsome. 4yo dark bay tb gelding, stands 16.3. By the up and coming hunter stallion Runnintothealter and out of a big bodied tb mare. …$6,000
Powderhorn, CO


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'Hobbit' alert: Evangeline Lilly joins the cast of the films
The Alberta-born actress has signed on to play a new character but director Peter Jackson won't reveal details.
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Evangeline Lilly has joined the cast of The Hobbit movies.
The Alberta-born actress has signed on to play a new character, Tauriel, but director Peter Jackson refused to give any further details about the woodland elf.
The filmmaker revealed on his Facebook page: "Her name means 'daughter of Mirkwood' and, beyond that, we must leave you guessing! (No, there is no romantic connection to Legolas.)"
Also joining the cast for the start of the second block of shooting is Australian actor Barry Humphries, best known for his female comedic alter ego Dame Edna Everage, who will portray the Goblin King, with extensive use of motion capture technology.
Jackson said: "We're looking forward to seeing him invest the Goblin King with the delicate sensitivity and emotional depth this character deserves."
Last week, it was announced Luke Evans and Benedict Cumberbatch had joined the cast of the two movies, playing Bard and Smaug respectively.
The Hobbit: An Unexpected Journey and The Hobbit: There and Back Again will be released in 2012 and 2013 respectively. Both releases will star Martin Freeman as the titular character.
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Ambergris Caye Directory
FlashbacksJuly 4, 2011 - 00:00
Dia De San Pedro Procession
Ever since our good old Parish Priest, Rev. Robert Raszkowski, popularly known as Father Raz, initiated this sea procession to honor our Patron Saint Peter, it has become a very significant annual event in the Roman Catholic Church and this community. It gives all the men of the sea- fishermen, divers and tour guides plus others an opportunity to have their sea vessels blessed in the hope of bringing stability to their jobs and protecting them from storms and misfortunes at sea. It also gives the families the opportunity to meet at church as a one unified community to honor our patron and to commit our pledges as good Sanpedranos. Check out this flashback photo in the 1980's where we see well known Catholic faithfuls like Dee Dee, Chejel, and our beloved Father Raz (R.I.P,)
Flashback pictures of San Pedro, Ambergris Caye are welcomed!
Please send pictures to Ambergris Today at: [email protected]
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