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text:
This page contains Wanted: Weapons Of Fate Hints for Xbox 360 called "Easy Bonus Mode" and has been posted or updated on Jul 15, 2010 by invader513.
- Developer: Grin
- Publisher: Warner Bros. Interactive Entertainment
- Genre: Action Shooter Third-Person
- Release: Mar 24, 2009
- ESRB: Mature
Easy Bonus Mode
First, you must beat the game. Begin a new game in Headshot Mode (for Dr. Lobotomy), Time Attack Mode (for Catch Me If You Can) or Close Combat Mode (for Butcher Would Be Proud) and play the first two scenes of the first level and complete them. When the third scene loads, quit to main menu. Go to Unlocked Acts and click the last level, choose any character, then choose the same difficulty you had it on before. Ignore the message begin the level. Now you just have to beat the whole last level, and you can even use cheats throughout the level -- just not on the last scene where you fight Immortal. Repeat for the other Achievements / Modes.
Please submit a problem for any incomplete, non-working or fake cheat listed above.
Stuck in this game? Set a specific, clearly defined question and let other gamers answer your question or view answers to previously asked questions. If you think you are an expert then please try to help others with their questions.
From: CJJHJJ
Posted on: 06-10-2011
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subset: commoncrawl


text:
Nature Communications
[SJR: 5.682] [H-I: 56] [96 followers] Follow
Open Access journal
ISSN (Online) 2041-1723
Published by Nature Publishing Group [117 journals]
- Ultraflexible organic amplifier with biocompatible gel electrodes
Authors: Tsuyoshi Sekitani, Tomoyuki Yokota, Kazunori Kuribara, Martin Kaltenbrunner, Takanori Fukushima, Yusuke Inoue, Masaki Sekino, Takashi Isoyama, Yusuke Abe, Hiroshi Onodera, Takao Someya
Abstract: Flexible electronics promise the opportunity to monitor biological activity via implanted devices. Here, the authors develop a biocompatible conductive carbon nanotube/gel composite and couple it with an ultrathin flexible amplifier, enabling in vivo measurement of epicardial electrocardiogram signals.
Citation: Nature Communications
PubDate: 2016-04-29|2016-04-29
DOI: 10.1038/ncomms11425
- Asparagine promotes cancer cell proliferation through use as an amino acid
exchange factor
Authors: Abigail S. Krall, Shili Xu, Thomas G. Graeber, Daniel Braas, Heather R. Christofk
Abstract: Cancer cells have been shown to be dependent upon glutamine for growth. Here, the authors show that intracellular asparagine, a glutamine-derived metabolite, is critical to cancer cell growth and can compensate glutamine deficiency by acting as an amino acid exchange factor.
Citation: Nature Communications
PubDate: 2016-04-29|2016-04-29
DOI: 10.1038/ncomms11457
- Mode engineering for realistic quantum-enhanced interferometry
Abstract: Quantum interferometry suffers from residual distinguishability between input photons. Here, the authors show theoretically and experimentally, in a two-photon measurement, how to overcome this by manipulating additional degrees of freedom.
Citation: Nature Communications
PubDate: 2016-04-29|2016-04-29
DOI: 10.1038/ncomms11411
- RhoA determines lineage fate of mesenchymal stem cells by modulating
CTGF–VEGF complex in extracellular matrix
Authors: Changjun Li, Gehua Zhen, Yu Chai, Liang Xie, Janet L. Crane, Emily Farber, Charles R. Farber, Xianghang Luo, Peisong Gao, Xu Cao, Mei Wan
Abstract: It is unclear what regulates the fate of mesenchymal stem cells (MSCs) in arterial repair following injury. Here, the authors show that MSC differentiation following injury is triggered by RhoA which in turn stimulates the release of connective tissue growth factor and vascular endothelial growth factor.
Citation: Nature Communications
PubDate: 2016-04-29|2016-04-29
DOI: 10.1038/ncomms11455
- Converging flow and anisotropy cause large-scale folding in Greenland's
ice sheet
Authors: Paul D. Bons, Daniela Jansen, Felicitas Mundel, Catherine C. Bauer, Tobias Binder, Olaf Eisen, Mark W. Jessell, Maria-Gema Llorens, Florian Steinbach, Daniel Steinhage, Ilka Weikusat
Abstract: A range of mechanisms has been proposed for large-scale folding in polar ice sheets. Here, using new three-dimensional reconstructions of such folds in the onset region of the Greenland Petermann Glacier, the authors show that these formed due to flow convergence and the high mechanical anisotropy of ice.
Citation: Nature Communications
PubDate: 2016-04-29|2016-04-29
DOI: 10.1038/ncomms11427
- Expression of a functional oxygen-labile nitrogenase component in the
mitochondrial matrix of aerobically grown yeast
Abstract: The sensitivity of nitrogenase to oxygen is a major barrier to engineer biological nitrogen fixation into cereal crops by direct nif gene transfer. Here the authors use yeast to show that targeting nitrogenase Fe protein to the mitochondrial matrix overcomes the O 2 sensitivity impediment.
Citation: Nature Communications
PubDate: 2016-04-29|2016-04-29
DOI: 10.1038/ncomms11426
- Functionalization mediates heat transport in graphene nanoflakes
Abstract: The high thermal conductivity of graphene is considerably reduced when the two-dimensional material is in contact with a substrate. Here, the authors show that thermal management of a micro heater is improved using graphene-based films covalently bonded by amino-silane molecules to graphene oxide.
Citation: Nature Communications
PubDate: 2016-04-29|2016-04-29
DOI: 10.1038/ncomms11281
- Clks 1, 2 and 4 prevent chromatin breakage by regulating the Aurora
B-dependent abscission checkpoint
Authors: Eleni Petsalaki, George Zachos
Abstract: Cells delay completion of cytokinesis when chromatin is trapped at the intercellular bridge. Here, Petsalaki and Zachos report that Cdc-like kinases (Clks) 1, 2 and 4 localize to the midbody and phosphorylate the mitotic kinase Aurora B, imposing the abscission checkpoint to prevent premature abscission and chromatin breakage.
Citation: Nature Communications
PubDate: 2016-04-29|2016-04-29
DOI: 10.1038/ncomms11451
- Quantum Einstein-de Haas effect
Authors: Marc Ganzhorn, Svetlana Klyatskaya, Mario Ruben, Wolfgang Wernsdorfer
Abstract: The Einstein-de Haas effect is a manifestation of the conservation of angular momentum, causing a magnetic object to rotate as its magnetization state is changed. Here, the authors demonstrate this effect at the single spin level for a molecular magnet suspended on a nanomechanical resonator.
Citation: Nature Communications
PubDate: 2016-04-29|2016-04-29
DOI: 10.1038/ncomms11443
- Myoscape controls cardiac calcium cycling and contractility via regulation
of L-type calcium channel surface expression
Abstract: Heart failure is a major public health issue but due to our poor disease understanding the current therapies are symptomatic. Here the authors identify Myoscape as a novel cardiac protein regulating membrane localization of the L-type calcium channel and heart's contractile force, thus promising new therapeutic avenues for heart failure.
Citation: Nature Communications
PubDate: 2016-04-28|2016-04-28
- Structural basis of oncogenic histone H3K27M inhibition of human polycomb
repressive complex 2
Authors: Neil Justin, Ying Zhang, Cataldo Tarricone, Stephen R. Martin, Shuyang Chen, Elizabeth Underwood, Valeria De Marco, Lesley F. Haire, Philip A. Walker, Danny Reinberg, Jon R. Wilson, Steven J. Gamblin
Abstract: Polycomb repressive complex 2 (PRC2) silences gene expression through trimethylation of K27 of histone H3 (H3K27Me). Here, the authors report the structure of the human PRC2 complex bound to the oncogenic H3K27M mutant, and suggest a mechanism for its potency in childhood brain cancers.
Citation: Nature Communications
PubDate: 2016-04-28|2016-04-28
DOI: 10.1038/ncomms11316
- Imaging large-scale cellular activity in spinal cord of freely behaving
Authors: Kohei J. Sekiguchi, Pavel Shekhtmeyster, Katharina Merten, Alexander Arena, Daniela Cook, Elizabeth Hoffman, Alexander Ngo, Axel Nimmerjahn
Abstract: Imaging cellular activity in mouse spinal cord has been historically difficult. Here the authors develop cellular resolution fluorescence imaging approaches in the spinal cord of behaving mice, and report distinct activity patterns of neurons and astrocytes in response to different sensory inputs.
Citation: Nature Communications
PubDate: 2016-04-28|2016-04-28
DOI: 10.1038/ncomms11450
- DNMT3B isoforms without catalytic activity stimulate gene body methylation
as accessory proteins in somatic cells
Authors: Christopher E. Duymich, Jessica Charlet, Xiaojing Yang, Peter A. Jones, Gangning Liang
Abstract: De novo DNA methylation is carried out by DNA methyltransferase DNMT3A/B, although DNMT3B isoforms without active catalytic domains are widely expressed. Here, the authors show that DNMT3B isoforms stimulate gene body methylation and re-methylation independently of the isoforms' catalytic activity.
Citation: Nature Communications
PubDate: 2016-04-28|2016-04-28
DOI: 10.1038/ncomms11453
- An essential malaria protein defines the architecture of blood-stage and
transmission-stage parasites
Authors: Sabrina Absalon, Jonathan A. Robbins, Jeffrey D. Dvorin
Abstract: Blood-stage malaria parasites replicate through a specialised type of cell division known as schizogony. Here, Absalon et al . identify a parasite protein that is essential during schizogony for cytokinesis and formation of the inner membrane complex, the structural scaffold of daughter parasites.
Citation: Nature Communications
PubDate: 2016-04-28|2016-04-28
DOI: 10.1038/ncomms11449
- Trapping mammalian protein complexes in viral particles
Authors: Sven Eyckerman, Kevin Titeca, Emmy Van Quickelberghe, Eva Cloots, Annick Verhee, Noortje Samyn, Leentje De Ceuninck, Evy Timmerman, Delphine De Sutter, Sam Lievens, Serge Van Calenbergh, Kris Gevaert, Jan Tavernier
Abstract: A large portion of the proteome carries out its cellular function as part of macromolecular complexes. Here the authors describe Virotrap, a novel lysis-free approach for the isolation and identification of biologically relevant protein-protein and small molecule-protein interactions.
Citation: Nature Communications
PubDate: 2016-04-28|2016-04-28
DOI: 10.1038/ncomms11416
- Polycomb repressive complex 2 structure with inhibitor reveals a mechanism
of activation and drug resistance
Abstract: Polycomb repressive complex 2 (PRC2) mediates gene silencing through chromatin reorganization by methylation of histone H3 lysine 27 (H3K27). Here, the authors present crystal structures of the inhibitor-bound wild-type and a mutant form of PRC2.
Citation: Nature Communications
PubDate: 2016-04-28|2016-04-28
DOI: 10.1038/ncomms11384
- A cell cycle kinase with tandem sensory PAS domains integrates cell fate
Authors: Thomas H. Mann, W. Seth Childers, Jimmy A. Blair, Michael R. Eckart, Lucy Shapiro
Abstract: The membrane-bound kinase CckA controls the activity of the Caulobacter crescentus master regulator CtrA, which in turn coordinates asymmetric cell division. Here, the authors show that CckA contains two sensory domains that have distinct sensitivities to fluctuations in cyclic-di-GMP concentration and subcellular niche.
Citation: Nature Communications
PubDate: 2016-04-27|2016-04-27
DOI: 10.1038/ncomms11454
- NMDA receptors are selectively partitioned into complexes and
supercomplexes during synapse maturation
Abstract: NMDARs and MAGUK proteins are capable of forming higher-order protein assemblies, however their organisation in the intact brain is unclear. Here, Frank et al . identify mouse and human supercomplexes and discover their mechanism of assembly using genetic tagging and affinity purification.
Citation: Nature Communications
PubDate: 2016-04-27|2016-04-27
DOI: 10.1038/ncomms11264
- Corrigendum: Growth of semiconducting single-wall carbon nanotubes with a
narrow band-gap distribution
Authors: Feng Zhang, Peng-Xiang Hou, Chang Liu, Bing-Wei Wang, Hua Jiang, Mao-Lin Chen, Dong-Ming Sun, Jin-Cheng Li, Hong-Tao Cong, Esko I. Kauppinen, Hui-Ming Cheng
Citation: Nature Communications
PubDate: 2016-04-27|2016-04-27
DOI: 10.1038/ncomms11563
- Epigenetic profiles signify cell fate plasticity in unipotent
spermatogonial stem and progenitor cells
Authors: Ying Liu, Eugenia G. Giannopoulou, Duancheng Wen, Ilaria Falciatori, Olivier Elemento, C. David Allis, Shahin Rafii, Marco Seandel
Abstract: Spermatogonial stem cells (SSCs) spontaneously convert to multipotent adult spermatogonial-derived stem cells (MASCs). Here, the authors reveal the dynamics of bivalent histone H3-lysine4 and -lysine27 methylation signatures at somatic gene promoters in SSCs and ESC-like promoter chromatin states in MASCs.
Citation: Nature Communications
PubDate: 2016-04-27|2016-04-27
DOI: 10.1038/ncomms11275
- Homotypic cell competition regulates proliferation and tiling of zebrafish
pigment cells during colour pattern formation
Abstract: Melanophores, iridophores and xanthophores are pigment-cell types that interact to form the stripes in zebrafish. Here, the authors study the interaction between cells of the same kind and show that each pigment-cell type covers the skin by contact based competition.
Citation: Nature Communications
PubDate: 2016-04-27|2016-04-27
DOI: 10.1038/ncomms11462
- Sn-doped Bi1.1Sb0.9Te2S bulk crystal topological insulator with excellent
Abstract: An ideal topological insulator possesses an insulating bulk and a unique conducting surface however such behaviour is typically inhibited by bulk conduction due to defects. Here, the authors show that Sn-doped Bi 1.1 Sb 0.9 Te 2 S grown by the vertical Bridgman technique might overcome this hurdle.
Citation: Nature Communications
PubDate: 2016-04-27|2016-04-27
DOI: 10.1038/ncomms11456
- Identification of four novel susceptibility loci for oestrogen receptor
negative breast cancer
Abstract: Oestrogen negative breast cancer is associated with a poor prognosis. In this study, the authors perform a meta-analysis of 11 breast cancer genome-wide association studies and identify four new loci associated with oestrogen negative breast cancer risk. These findings may aid in stratifying patients in the clinic.
Citation: Nature Communications
PubDate: 2016-04-27|2016-04-27
DOI: 10.1038/ncomms11375
- Optical painting and fluorescence activated sorting of single adherent
cells labelled with photoswitchable Pdots
Authors: Chun-Ting Kuo, Alison M. Thompson, Maria Elena Gallina, Fangmao Ye, Eleanor S. Johnson, Wei Sun, Mengxia Zhao, Jiangbo Yu, I-Che Wu, Bryant Fujimoto, Christopher C. DuFort, Markus A. Carlson, Sunil R. Hingorani, Amy L. Paguirigan, Jerald P. Radich, Daniel T. Chiu
Abstract: Isolation of individual cells from mixed populations is desirable for many biomedical applications. Here the authors use photoswitchable Pdots to allow 'optical painting', where cells of interest are marked based on their visual characteristics, and can then be isolated by fluorescence activated cell sorting.
Citation: Nature Communications
PubDate: 2016-04-27|2016-04-27
DOI: 10.1038/ncomms11468
- Exosomal microRNA miR-92a concentration in serum reflects human brown fat
Authors: Yong Chen, Joschka J. Buyel, Mark J. W. Hanssen, Franziska Siegel, Ruping Pan, Jennifer Naumann, Michael Schell, Anouk van der Lans, Christian Schlein, Holger Froehlich, Joerg Heeren, Kirsi A. Virtanen, Wouter van Marken Lichtenbelt, Alexander Pfeifer
Abstract: Exosomes are RNA-containing lipid vesicles with roles in inter-tissue crosstalk. Here the authors show that exosome release from brown adipocytes is increased upon thermogenic activation, both in vitro and in vivo , and demonstrate that serum levels of exosomal miR-92 reflect brown fat activity in humans.
Citation: Nature Communications
PubDate: 2016-04-27|2016-04-27
DOI: 10.1038/ncomms11420
- Line tension at lipid phase boundaries as driving force for HIV fusion
peptide-mediated fusion
Authors: Sung-Tae Yang, Volker Kiessling, Lukas K. Tamm
Abstract: HIV preferentially fuses with lipid membranes at the interface between ordered and disordered domains, but the mechanistic basis for this observation is not known. Here Yang et al . show that line tension at the lipid boundary contributes considerable energy to drive gp41 fusion peptide-mediated fusion.
Citation: Nature Communications
PubDate: 2016-04-26|2016-04-26
DOI: 10.1038/ncomms11401
- Highly selective hydrogenation of arenes using nanostructured ruthenium
catalysts modified with a carbon–nitrogen matrix
Abstract: The selective reduction of arenes is important in organic synthesis and also valorization of biomass. Here, the authors report the use of ruthenium-based nanoparticles, which display high activity in arene reduction and preferentially hydrogenate aromatic rings rather than cleaving etheric C-O bonds.
Citation: Nature Communications
PubDate: 2016-04-26|2016-04-26
DOI: 10.1038/ncomms11326
- Protein-directed self-assembly of a fullerene crystal
Authors: Kook-Han Kim, Dong-Kyun Ko, Yong-Tae Kim, Nam Hyeong Kim, Jaydeep Paul, Shao-Qing Zhang, Christopher B. Murray, Rudresh Acharya, William F. DeGrado, Yong Ho Kim, Gevorg Grigoryan
Abstract: Self-assembly enables complex structures to be fabricated from a few relatively simple components, but requires a detailed understanding of how the constituents may interact. Here, the authors report the rational assembly and crystallographic characterization of a fullerene-protein superstructure.
Citation: Nature Communications
PubDate: 2016-04-26|2016-04-26
DOI: 10.1038/ncomms11429
- Elasticity-induced force reversal between active spinning particles in
dense passive media
Authors: J. L. Aragones, J. P. Steimel, A. Alexander-Katz
Abstract: Physics out-of-equilibrium is necessary to understand a variety of interactions, for example in biological systems. Here, the authors show that the interactions between non-Brownian active spinning particles can change from repulsive to attractive depending on the properties of the surrounding passive medium.
Citation: Nature Communications
PubDate: 2016-04-26|2016-04-26
DOI: 10.1038/ncomms11325
- All-optical design for inherently energy-conserving reversible gates and
Authors: Eyal Cohen, Shlomi Dolev, Michael Rosenblit
Abstract: Reversible gates, like Fredkin gates, may be useful for energy conservation efforts. Cohen et al . present a formalism that may be used to produce any reversible logic. This method is implemented over an optical design of the Fredkin gate which utilizes only optical elements that inherently conserve energy.
Citation: Nature Communications
PubDate: 2016-04-26|2016-04-26
DOI: 10.1038/ncomms11424
- Diverse human extracellular RNAs are widely detected in human plasma
Authors: Jane E. Freedman, Mark Gerstein, Eric Mick, Joel Rozowsky, Daniel Levy, Robert Kitchen, Saumya Das, Ravi Shah, Kirsty Danielson, Lea Beaulieu, Fabio C. P. Navarro, Yaoyu Wang, Timur R. Galeev, Alex Holman, Raymond Y. Kwong, Venkatesh Murthy, Selim E. Tanriverdi, Milka Koupenova-Zamor, Ekaterina Mikhalev, Kahraman Tanriverdi
Abstract: Extracellular miRNAs are present in a variety of bodily fluids. Here, Freedman et al . analysed plasma-derived RNA by RNA-seq from 40 people followed by targeted RT-qPCR in an additional 2,763 people, and report over 1,000 extracellular RNAs including microRNAs, piwi-interacting RNA and small nucleolar RNAs.
Citation: Nature Communications
PubDate: 2016-04-26|2016-04-26
DOI: 10.1038/ncomms11106
- Erratum: Oxygen depletion recorded in upper waters of the glacial Southern
Authors: Zunli Lu, Babette A. A. Hoogakker, Claus-Dieter Hillenbrand, Xiaoli Zhou, Ellen Thomas, Kristina M. Gutchness, Wanyi Lu, Luke Jones, Rosalind E. M. Rickaby
Citation: Nature Communications
PubDate: 2016-04-26|2016-04-26
DOI: 10.1038/ncomms11531
- Strong nonlinear terahertz response induced by Dirac surface states in
Bi2Se3 topological insulator
Authors: Flavio Giorgianni, Enrica Chiadroni, Andrea Rovere, Mariangela Cestelli-Guidi, Andrea Perucchi, Marco Bellaveglia, Michele Castellano, Domenico Di Giovenale, Giampiero Di Pirro, Massimo Ferrario, Riccardo Pompili, Cristina Vaccarezza, Fabio Villa, Alessandro Cianchi, Andrea Mostacci, Massimo Petrarca, Matthew Brahlek, Nikesh Koirala, Seongshik Oh, Stefano Lupi
Abstract: The terahertz response of topological insulator surface states, in which relativistic electrons are protected from backscattering, possesses potential optic and plasmonic applications. Here, the authors demonstrate a nonlinear absorption response of Bi 2 Se 3 to terahertz electric fields.
Citation: Nature Communications
PubDate: 2016-04-26|2016-04-26
DOI: 10.1038/ncomms11421
- Neural substrates of cognitive biases during probabilistic inference
Authors: Alireza Soltani, Peyman Khorsand, Clara Guo, Shiva Farashahi, Janet Liu
Abstract: Humans are often biased in estimating the precise influence of probabilistic events on their decisions. Here, Khorsand and colleagues report a behavioural task that produces these biases in inference and describe a biophysically-plausible model that captures these behavioural deviations from optimal decision making.
Citation: Nature Communications
PubDate: 2016-04-26|2016-04-26
DOI: 10.1038/ncomms11393
- miR-22 has a potent anti-tumour role with therapeutic potential in acute
myeloid leukaemia
Authors: Xi Jiang, Chao Hu, Stephen Arnovitz, Jason Bugno, Miao Yu, Zhixiang Zuo, Ping Chen, Hao Huang, Bryan Ulrich, Sandeep Gurbuxani, Hengyou Weng, Jennifer Strong, Yungui Wang, Yuanyuan Li, Justin Salat, Shenglai Li, Abdel G. Elkahloun, Yang Yang, Mary Beth Neilly, Richard A. Larson, Michelle M. Le Beau, Tobias Herold, Stefan K. Bohlander, Paul P. Liu, Jiwang Zhang, Zejuan Li, Chuan He, Jie Jin, Seungpyo Hong, Jianjun Chen
Abstract: Mir-22 has been shown to be an oncogenic microRNA in breast cancer and myelodysplastic syndrome. Here, the authors show that mir-22 functions as a tumour suppressor in de novo acute myeloid leukaemia by inhibiting the expression of several oncogenes and that restoring mir-22 expression suppresses AML progression.
Citation: Nature Communications
PubDate: 2016-04-26|2016-04-26
DOI: 10.1038/ncomms11452
- An inhibitor of chondroitin sulfate proteoglycan synthesis promotes
central nervous system remyelination
Authors: Michael B. Keough, James A. Rogers, Ping Zhang, Samuel K. Jensen, Erin L. Stephenson, Tieyu Chen, Mitchel G. Hurlbert, Lorraine W. Lau, Khalil S. Rawji, Jason R. Plemel, Marcus Koch, Chang-Chun Ling, V. Wee Yong
Abstract: Chondroitin sulfate proteoglycans (CSPGs) secreted by astrocytes are known to inhibit OPC differentiation and remyelination. Here, the authors identify a novel CSPG synthesis inhibitor and find it can rescue OPC differentiation in vitro and accelerate remyelination in mice following focal demyelination.
Citation: Nature Communications
PubDate: 2016-04-26|2016-04-26
DOI: 10.1038/ncomms11312
- Network dynamics in nanofilled polymers
Authors: Guilhem P. Baeza, Claudia Dessi, Salvatore Costanzo, Dan Zhao, Shushan Gong, Angel Alegria, Ralph H. Colby, Michael Rubinstein, Dimitris Vlassopoulos, Sanat K. Kumar
Abstract: The mixture of nanoparticles and polymers can dramatically alter the dynamics of the resulting system, but the detail is still under debate. Here, Baeza et al . show the formation of a percolated network by polymer bridging between adjacent nanoparticles as nanoparticle concentration increases.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11368
- Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the
metastasis of prostate cancer
Authors: Shih-Chieh Lin, Chung-Yang Kao, Hui-Ju Lee, Chad J. Creighton, Michael M. Ittmann, Shaw-Jenq Tsai, Sophia Y. Tsai, Ming-Jer Tsai
Abstract: The orphan nuclear receptor COUP-TFII is highly expressed in metastatic prostate cancers and its overexpression accelerates prostate tumour progression in mouse models. Here, the author show that that loss of miR-101 and miR-27a in prostate cancer cells can lead to COUP-TFII expression which in turn directly regulates FOXM1 and CENPF favouring prostate cancer metastasis.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11418
- Contrasting effects of defaunation on aboveground carbon storage across
the global tropics
Authors: Anand M. Osuri, Jayashree Ratnam, Varun Varma, Patricia Alvarez-Loayza, Johanna Hurtado Astaiza, Matt Bradford, Christine Fletcher, Mireille Ndoundou-Hockemba, Patrick A. Jansen, David Kenfack, Andrew R. Marshall, B. R. Ramesh, Francesco Rovero, Mahesh Sankaran
Abstract: Defaunation is linked to the decline of tree species that depend on large animals for seed dispersal, but it is unclear if this affects carbon storage. Here the authors show that defaunation effects on carbon storage vary across continents, driven by relationships between seed dispersal strategies and adult tree size.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11351
- Phosphotransferase-dependent accumulation of (p)ppGpp in response to
glutamine deprivation in Caulobacter crescentus
Abstract: The small molecule (p)ppGpp is commonly produced by bacteria as a signal of nutrient starvation. Here, Ronneau et al . show that (p)ppGpp accumulation in the model bacterium Caulobacter crescentus is modulated by a nitrogen-related phosphotransferase system in response to glutamine deprivation.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11423
- Insights into the activation mechanism of class I HDAC complexes by
inositol phosphates
Authors: Peter J. Watson, Christopher J. Millard, Andrew M. Riley, Naomi S. Robertson, Lyndsey C. Wright, Himali Y. Godage, Shaun M. Cowley, Andrew G. Jamieson, Barry V. L. Potter, John W. R. Schwabe
Abstract: Class I histone deacetylase complexes can be activated by inositol phosphates. Here, the authors investigate the stereochemical requirements for activation; use the crystal structure to understand substrate recognition, and suggest an entropically driven mechanism of allostery.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11262
- miRNA863-3p sequentially targets negative immune regulator ARLPKs and
positive regulator SERRATE upon bacterial infection
Authors: Dongdong Niu, Yifan E. Lii, Padmanabhan Chellappan, Lei Lei, Karl Peralta, Chunhao Jiang, Jianhua Guo, Gitta Coaker, Hailing Jin
Abstract: Small RNA plays an important role in regulating the plant defence against bacterial pathogens. Here the authors propose that miR863-3p acts to fine-tune the timing of defence responses by sequentially silencing negative and positive regulators of the plant immune response.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11324
- The obesity-induced transcriptional regulator TRIP-Br2 mediates visceral
fat endoplasmic reticulum stress-induced inflammation
Abstract: Visceral and subcutaneous fat are associated with different metabolic risk, but mediators of such depot specific effects are not very well known. Here the authors identify the transcriptional regulator, TRIP-Br2, as a regulator of endoplasmic reticulum (ER) stress-induced inflammatory responses specifically in visceral fat.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11378
- Mechanical cell competition kills cells via induction of lethal p53 levels
Abstract: Cell competition is a quality control mechanism to eliminate unfit cells. Here the authors show that physical compaction of less fit cells surrounded by healthy neighbours leads to increased expression of tumour suppressor p53 in the compacted cells, causing cell death.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11373
- Arabidopsis PROTEASOME REGULATOR1 is required for auxin-mediated
suppression of proteasome activity and regulates auxin signalling
Authors: Bao-Jun Yang, Xin-Xin Han, Lin-Lin Yin, Mei-Qing Xing, Zhi-Hong Xu, Hong-Wei Xue
Abstract: Plant responses to auxin require proteasome-mediated degradation of Aux/IAA transcriptional repressor proteins. Here, Yang et al . show that auxin suppresses proteasome activity in a manner dependent on the proteasome regulator PTRE1 and propose a mechanism for fine tuning Aux/IAA homoeostasis.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11388
- Thiol reductive stress induces cellulose-anchored biofilm formation in
Mycobacterium tuberculosis
Authors: Abhishek Trivedi, Parminder Singh Mavi, Deepak Bhatt, Ashwani Kumar
Abstract: When grown in the lab, Mycobacterium tuberculosis can form pellicle biofilms. Here, Trivedi et al . show that thiol reductive stress (induced by dithiothreitol) triggers rapid formation of thicker biofilms containing cellulose as well as antibiotic-tolerant, metabolically active bacteria.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11392
- Host gene constraints and genomic context impact the expression and
evolution of human microRNAs
Abstract: Recent miRNAs tend to emerge within coding genes. Here, by analysing miRNA expression data from six species and comparing genomes from 13 species, the authors report that host genes may provide stronger expression constraints to intragenic miRNAs in the long run.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11438
- Spontaneous formation and base pairing of plausible prebiotic nucleotides
in water
Authors: Brian J. Cafferty, David M. Fialho, Jaheda Khanam, Ramanarayanan Krishnamurthy, Nicholas V. Hud
Abstract: One of the questions for prebiotic chemistry is the formation of complementary base pairing systems. Here, the authors show that plausible two prebiotic heterocycles can form glycosidic bonds with ribose in water and that these spontaneously base-pair in aqueous solution.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11328
- Single-cell RNA-seq reveals cell type-specific transcriptional signatures
at the maternal–foetal interface during pregnancy
Authors: Andrew C. Nelson, Arne W. Mould, Elizabeth K. Bikoff, Elizabeth J. Robertson
Abstract: The zinc finger transcriptional repressor Prdm1 /Blimp1 is essential for remodelling maternal blood vessels in a subset of trophoblast cells. Here, the authors perform single-cell RNA-seq analysis on this Blimp1+ lineage, identifying functionally distinct cell types present at the maternal–foetal interface.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11414
- Enhanced nonlinear interactions in quantum optomechanics via mechanical
Authors: Marc-Antoine Lemonde, Nicolas Didier, Aashish A. Clerk
Abstract: Optomechanics harnesses the interaction between mechanical resonators and light, but weak matter–single-photon interactions limit studies to the linear regime. Here, the authors show that the interaction can be enhanced by modulating the spring constant of the resonator.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11338
- Foldamer-mediated manipulation of a pre-amyloid toxin
Authors: Sunil Kumar, Melissa Birol, Diana E. Schlamadinger, Slawomir P. Wojcik, Elizabeth Rhoades, Andrew D. Miranker
Abstract: Intrinsically disordered proteins that form amyloid fibrils are hard to target with traditional therapeutic approaches. Here, the authors report on an oligoquinoline derivative that binds the human islet amyloid polypeptide, stabilising an alpha-helical structure that reduces its cellular toxicity.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11412
- A genetic basis for the variation in the vulnerability of cancer to DNA
Authors: Brian D. Yard, Drew J. Adams, Eui Kyu Chie, Pablo Tamayo, Jessica S. Battaglia, Priyanka Gopal, Kevin Rogacki, Bradley E. Pearson, James Phillips, Daniel P. Raymond, Nathan A. Pennell, Francisco Almeida, Jaime H. Cheah, Paul A. Clemons, Alykhan Shamji, Craig D. Peacock, Stuart L. Schreiber, Peter S. Hammerman, Mohamed E. Abazeed
Abstract: The variability in patient response to radiation treatment is difficult to predict. Here, using more than 500 cell lines the authors measure response to radiation exposure and a large panel of compounds, and show that response can be predicted by genetic alterations of the cells.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11428
- Identifying genetically driven clinical phenotypes using linear mixed
Authors: Jonathan D. Mosley, John S. Witte, Emma K. Larkin, Lisa Bastarache, Christian M. Shaffer, Jason H. Karnes, C. Michael Stein, Elizabeth Phillips, Scott J. Hebbring, Murray H. Brilliant, John Mayer, Zhan Ye, Dan M. Roden, Joshua C. Denny
Abstract: Use of general linear mixed models (GLMMs) in genetic variance analysis can quantify the relative contribution of additive effects from genetic variation on a given trait. Here, Jonathan Mosley and colleagues apply GLMM in a phenome-wide analysis and show that genetic variations in the HLA region are associated with 44 phenotypes, 5 phenotypes which were not previously reported in GWASes.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11433
- Retroviral intasomes search for a target DNA by 1D diffusion which rarely
results in integration
Authors: Nathan D. Jones, Miguel A. Lopez Jr, Jeungphill Hanne, Mitchell B. Peake, Jong-Bong Lee, Richard Fishel, Kristine E. Yoder
Abstract: Retroviral Integration into the host DNA is a rare event with evidence suggesting that it relies on DNA topology and sequence. Here the authors present single molecule evidence that shows the retroviral integration machinery vigorously scans the target DNA by 1D-diffusion but infrequently integrates.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11409
- A modular design of molecular qubits to implement universal quantum gates
Abstract: The physical implementation of quantum information processing requires individual qubits and entangling gates. Here, the authors demonstrate a modular implementation through chemistry, assembling molecular {Cr 7 Ni} rings acting as qubits, with supramolecular structures realizing gates by choice of the linker.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11377
- Comparative analysis of ear-hole closure identifies epimorphic
regeneration as a discrete trait in mammals
Authors: Thomas R. Gawriluk, Jennifer Simkin, Katherine L. Thompson, Shishir K. Biswas, Zak Clare-Salzler, John M. Kimani, Stephen G. Kiama, Jeramiah J. Smith, Vanessa O. Ezenwa, Ashley W. Seifert
Abstract: The extent to which mammals and other vertebrates share similar mechanisms of tissue regeneration is unclear. Here, the authors use an ear punch assay in spiny mice, which regenerate fully, to show blastema formation and mesenchymal cell proliferation as cell cycle regulators p21 and p27 remain cytoplasmic.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11164
- The HSP70 co-chaperone DNAJC14 targets misfolded pendrin for
unconventional protein secretion
Authors: Jinsei Jung, Jiyoon Kim, Shin Hye Roh, Ikhyun Jun, Robert D. Sampson, Heon Yung Gee, Jae Young Choi, Min Goo Lee
Abstract: Mutations in pendrin, a plasma membrane transporter, lead to Pendred syndrome, which is associated with hearing loss. Here, Jung et al . show that cell-surface expression of a mutated form of pendrin can be restored by blocking ER-to-Golgi traffic and triggering a DNAJC14 dependent unconventional secretion pathway.
Citation: Nature Communications
PubDate: 2016-04-25|2016-04-25
DOI: 10.1038/ncomms11386


text:
- Score:
- rated 4.42 / 5 stars
- Views:
- 971,244 Views
- Share Links:
- Genre:
- Action - Platformer - Other
- future
- lasers
- crabs
- time-travel
Credits & Info
- Uploaded
- Jan 6, 2011 | 8:55 PM EST
- Frontpaged January 7, 2011
- Weekly 5th Place January 12, 2011
If you liked this, check these out!
Author Comments
Rated 5 / 5 stars
omg ninjamil you can be rubbish this game is friggin' awesome XD I love it when the other man from the future comes a little now and then says something: "I SHOULD BE PASSING OUT BY NOW!" XD
Rated 5 / 5 stars
In the final boss I had no idea how to beat it and I won... will you make more games like this?
Rated 5 / 5 stars
I couln't have done a better job.
Awesome voices, gameplay, ect.
Rated 1 / 5 stars
"nO TIME TO EXPLAIN" UH?
Good exuse for not having any ide for a story line, this stuff was rubbish.
Rated 4.5 / 5 stars
Best game ever.
A game where you can put on cool glasses or become a dinosaur? Excellent. Furthermore, you can become a dinosaur AND wear those cool glasses. That is pure awesome. Too bad the controls are a little edgy. Like how you can't lift off from the ground and must jump first. The laser is really hard to control properly. But its all cool. I get to kick some wierd t-rex/stegosaurus fusion so :D


text:
Kiwi attitude to risk-taking 'appalling'
Do you think Kiwis are averse to risk-taking in business?
Relevant offers
New Zealanders have an "appalling" attitude to business risk-takers, sitting on the fence and gloating when they fail, says Ministry of Foreign Affairs chief executive and secretary John Allen.
Speaking to a launch function for the Waikato Export Awards in Hamilton, Allen said to build a country in which people want to live and work, New Zealand needed to change and challenge some of its attitudes.
The former NZ Post chief executive said he had first-hand experience with the national attitude to risk-taking when that company launched Kiwibank.
"We took an enormous risk, backing our own hunch and analysis in the face of enormous hostility. It took guts but we built a business of substance which is continuing to contribute to New Zealand's future."
Allen, who joined MFAT three years ago and whose strategy for restructuring the ministry bought him a fight with diplomats and senior staff, said New Zealand needed more people who took risks.
"When they fail we will just stand them up and point them in the right direction."
Until New Zealanders changed their attitude to wealth and until New Zealand companies had stronger balance sheets and the capacity to invest in markets like Asia and the US, this country would not deliver its potential for success.
"We have to change our attitudes to business itself.
"We have to ensure we are sticking up for people ... far too often we see people taken down and taken down in a very overt and difficult way,'' Allen said.
"Too often we are timid and stand on the sidelines. The reality is it's up to us to stand up and talk about this. I believe absolutely that exporters have the drive to deliver that success.'
'Allen said the ministry and the Government were ''really committed'' to creating better access for New Zealand exporters to international markets and to delivering export businesses better margins.
- Waikato Times
Sponsored links
Waikato, BOP architecture awards celebrates visionary work
Contact Energy increases price of electricity bill
Regions benefit from main centre industrial space squeeze
Foss talks to Cambridge business owners
Pukekohe grower crowned king of the vegetables
Chinese firework factory visit opens eyes
Heat goes on Hamilton City Council staff over incomplete work
May Wang guilty of fraud over failed Crafar farms acquisition
Hamilton Airport passenger numbers do a 180
Supermarket chains appeal Hamilton's booze laws
Waikato and BOP architecture awards showcase "wildly imaginative" projects
Family of the late microlight pioneer Max Clear put his Te Kowhai airfield up for sale
Honeylab medical‐grade kanuka honey a vanguard for pharmaceutical honey industry
Former Waikato DHB psychiatrist up on sex charges
Pair plead guilty to Taupo boy's manslaughter
Judicial hearing likely for Melville's Jacob Ale after club rugby punch
Trial for Whangamata murder accused begins with warning for jury
Chinese billionaire Wang Wenyin looks at investing in tiny Kiwi goldmine
University of California's closer ties with Waikato
Couple hospitalised after car hits power pole
Firearms targeted in rural burglaries
Transforming Hamilton: Steve Hart has his say
School holds special place for principal
Funds squeeze hurts cancer patients
Top five things to do this weekend
Waikato trio succeed despite big setbacks
Pair plead guilty to Taupo boy's manslaughter
Man killed in Lindis Pass helicopter crash named
Chinese billionaire Wang Wenyin looks at investing in tiny Kiwi goldmine
Contact Energy increases price of electricity bill
Former Waikato DHB psychiatrist up on sex charges
Man in serious condition after rolling outside fire station
Broken tail lights lead to gun discovery for Morrinsville Police
Fire at rear of Flagstaff bakery
Man charged over fatal head-on motorcycle accident
Style and substance enduring qualities in New Zealand Super Rugby sweep
Ongoing attacks force horse trainers out of business


text:
More Drake Reference Tracks Surface, He's Still More Popular Than Beyoncé
Blood Type ft. Emilio Rojas - Writer's Block
Posted 5 years ago
Tags: Blood Type , Downloads
The Synthesis
2 Weeks Notice
Before they drop their DJBooth-hosted 2 Weeks Notice on March 7, Blood Type has decided to share another album inclusion with our readers. Writer's Block, produced by The Synthesis, features guest accompaniment from Life Without Shame author Emilio Rojas.
Blood Type Emilio Rojas Downloads
Written by DJ Z
Posted 5 years ago
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Sample Text - Sample Link


text:
Phone Unlock 1.0
Have you forgotten you phone's Lock Code? Phone Unlock will handle the situation!
Last update 20 Mar. 2006 Licence Free to try | $10.00 OS Support Mobile Downloads Total: 12,420 | Last week: 0 Ranking #2 in Utilities Publisher Mobifun Soft
Phone Unlock Publisher's Description
Phone Unlock
Some of us often forget the Lock Code of the phone minutes after the change. It is not such a problem any more. Phone Unlock resets phone's Lock Code in case you don't know it. The new code is the Phone Unlock Registration Key. You can first run Phone Unlock on your device and then register the program only after the successful reset of the Lock Code.
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text:
Agent Sue Faulkner
$500 per week
- 3
- 1
- 2
Showing 1 - 20 of 52 properties for rent by Bushby Property Group - LAUNCESTON
117 Cimitiere StreetLaunceston, Tas 7250
In 1914, George F.B. Bushby started Bushby & Co Estate Agents in Launceston. Back then, he would send his staff out on their push bikes to collect the rent. Over the past century, Bushby & Co has grown, evolving from Bushby First National to today's Bushby Property Group, now consisting of 35 staff and caring for over 1500 properties, Tasmania's largest rent roll. A century ago, George would have never believed that Bushby & Co would become a leading force in Tasmania's real estate industry. Today, Bushby Property Group reflects our standing as Northern Tasmania's most accomplished provider of real estate services.
Agent Sue Faulkner
$500 per week
Agent Kylee Gear
$320 per week
Agent Kristen Lynam
$310 per week
Agent Debbie Heron
280.00 Per week
Agent Kylee Gear
$330 per week
Agent Kylee Gear
$155 per week
Agent Ruth Cartwright
$300.00 weekly
Agent Ruth Cartwright
$290 per week
Agent Janice Hill
$310 per week
Agent Janice Hill
$280 per week
Agent Debbie Heron
$300 per week
Agent Debbie Heron
$380 per week
Agent Kylee Gear
$310 per week
Agent Debbie Heron
$395 per week
Agent Janice Hill
$265.00 weekly
Agent Ruth Cartwright
$160 per week
Agent Debbie Heron
$430 per week
Agent Janice Hill
$300 per week
Agent Janice Hill
$250 per week
Agent Debbie Heron
$230.00 per week
$310 per week
Great Position!
This spacious 4 bedroom home has been partly renovated over the years and is conveniently close to all amenities. Features: Renovated kitchen and...
$310 per week
Escape to Tranquility
This cosy home is set in the picturesque valley of Underwood while only being located a 20 minute drive from Launceston and a 5 minute drive to...
$250 per week
An Easy Life
Beautifully located to enjoy peaceful living, this well appointed unit offers - Tidy kitchen to spacious dining and living area 2 generous...
$120 per week
Avoid missing out - Share House
Share House Secure private room 2 bathrooms Large share kitchen with gas cooking Laundry room with a washing machine Cleaner supplied for the...
From $450 per week
Showcasing Launcestons Best
Situated in the idyllic township of Dilston, just 15 minutes from the Launceston CBD, this delightful residence offers: Superb views Modern well...
$260.00 per week
What a makeover!
This is a great renovation!!!! House rules fans will love it. Perfectly presented throughout with a touch of original charm: New kitchen with...
$320 per week
Spacious property in great location
This spacious residence is nestled on a large level block in highly sought after Mowbray. This home is waiting for you to settle in and make it...
East Launceston
...a long term tenancy
Just Renovated
This renovated two bedroom apartment is situated in popular St Georges Square, just 5 minutes from CBD. Modern kitchen & bathroom 2 bedrooms with...
From $450 per week
A beautiful home away from home!
Located just a minutes walk to the Launceston General Hospital and CBD, this well appointed home offers beautiful living: Quality kitchen 2...
$265.00 weekly
Delightful Family Home
Superbly located in quiet location in popular Newstead, this immaculately maintained home offers great living:- Open plan kitchen including brand...
East Launceston
$300 per week
Beautiful & Cosy In East Launceston
Located on a beautiful street in the desirable suburb of East Launceston is this gorgeous home. 2 bedrooms with built in wardrobes - Master with...
$160 per week
Neat & Tidy in Newstead!!
Perfectly located in Newstead, within walking distance to supermarket, local shops and public transport, is this neat and tidy one bedroom unit,...
$310 per week
3 Bedroom Home in Newstead
This three bedroom home is situated in a quiet area and is close to parks and schools. The property offers: Central kitchen open to dining area &...
Low Head
$500 per week
Enjoy stunning 180 degree views of the Bass Strait from the balcony. This is a very special home. Open plan kitchen, living room, & dining area...
$160 per week
Neat and tidy in Newnham!!
Perfectly located in popular Newnham, in a quite complex of three, close to the University, local shops and public transport, is this spacious...
280.00 Per week
That loving feeling
Enjoy living in this warm and cosy family home which is situated in a quiet street in Newstead. Neatly presented throughout with the option of...
South Launceston
$275 per week
Refurbished Character Home!!
This refurbished 3 bedroom family home located in popular South Launceston, offers: - An Upgraded kitchen - A Spacious lounge room warmed with...
South Launceston
$170 per week
Lovely unit, lovely views!!
Neatly presented one bedroom unit, within walking distance to local shops and public transport, offering: Spacious kitchen with ample storage...
$300.00 weekly
Charming cottage
This charming cottage has so much to offer. Situated close to the university and local shopping at Mowbray 3 bedrooms, main with fitted robes...
East Launceston
$270 per week
Close to the City
2 Bedroom Character Semi Detached Apartment Large loungeroom with bay window, high ceilings throughout. Warmed by a heatpump. Updated kitchen...
$300 per week
Prospect Family Home
Let the children walk to school while living in this conveniently located family home. Tidy throughout with a new heat pump, low maintenance...
$330 per week
Modern Living
This modern home is situated on a quiet street with beautiful surrounding views. 3 bedrooms all with built-ins Large open place kitchen/dining...
$195 per week
Multi Purpose Use
This converted shopfront in Invermay is a perfect solution for someone needing a bigger than usual 1 bedroom unit with study space for themselves...
$260 per week
Peaceful Family Home
Enjoying lovely views this spacious home offers perfect living - Tidy kitchen to dining area Sunny living room with woodheater 3 private bedrooms...
$270 per week
Charming and Spacious Home
Well positioned, this fantastic home ticks all the boxes. 3 bedrooms, master with built in wardrobes Large open plan kitchen, dining and lounge...


text:
Deltona Stables
1. Greystone Stables
I took my first horseback riding lessons from Piper and she never gave up on me. She worked really hard with me and made me love working for what I …
2. Equestrian Quest Training Park
4355 N CR 426Geneva, FL 32732
From Business: Welcome to Equestrian Quest, offering guided nature trail rides by appointment, horseback riding lessons for children and adults, leasing, boarding, birthday partie…
3. Faith Riders
2890 N Shell RdDeland, FL 32720
4. Diane Bauer's Heaven's Seventh
1985 E Osceola RdGeneva, FL 32732
5. Marcody Ranch
3804 Pioneer TrlNew Smyrna Beach, FL 32168
6. Calvary Combined-Training Center
4000 Cypress BndGeneva, FL 32732
7. Blue Skye Stables
2775 E Osceola RdGeneva, FL 32732
8. Over The Hill Farm
5130 Thomas Stable RdSanford, FL 32773
9. Seabreeze Farm
505 Old Mims RdGeneva, FL 32732
10. Trail Rides Rock Springs Run
Had my birthday party there. Had a great time riding all the great looking horses. The people who worked there gave us a tour and the history of the…
11. Amazing Grace Equestrian
200 Bay Meadow RoadLongwood, FL 32750
12. Cactus Jacks Trail Rides
31700 County Road 433Sorrento, FL 32776
13. Jopp's Tack Inc
love going to jopps they always have great service and good prices !
14. Shenandoah Stables
Love takng son out to ride! The owner is amazing and very helpful! And the man who cares for the horses would give his life for them ! Will aways go…
15. Dressage Center Inc
1307 Spring Garden Ranch RdDe Leon Springs, FL 32130
16. Sommersby Farms
3051 Riviera Bay CtOviedo, FL 32765
17. Wind Song Farms
2020 Haas RdApopka, FL 32712
18. Peach Racing Stable
2929 Turnbull Bay RdNew Smyrna Beach, FL 32168
19. Barrett Farm Inc
5100 Double R LnOviedo, FL 32765
20. Rustling Oaks Farm
A great place to visit. Owned and operated by a great person. Great place for starters & advanced and boarders.....
21. Eric Wolfe Arabians
2075 Haas RdApopka, FL 32712
22. Errol Equestrian Center Inc
359 W Lester RdApopka, FL 32712
23. Winter Park Farm
4501 Howell Branch RdWinter Park, FL 32792
24. Deep Creek Stables
2270 S County Road 3Pierson, FL 32180
From Business: Deep Creek Stables is located on 120 acres and there are over 18,000 acres of state forest to trail ride on. We also offer carraige rides, skeet shooting and horse …
25. Daytona Beach Equestrian Center
2552 Tomoka Farms RdPort Orange, FL 32128
26. Demaraz Farms Arabians
2552 Tomoka Farms RdPort Orange, FL 32128
27. Innovation Arabians
2552 Tomoka Farms RdPort Orange, FL 32128
28. Willingham Dressage
1785 Willingham RdChuluota, FL 32766
29. Twin Gaits Stables
30. Freedom Ride Inc
1905 Lee RdOrlando, FL 32810


text:
|By Business Wire
Article Rating:
|November 24, 2012 06:36 PM EST
Consumers will spend $43.7 billion on holiday gifts this Thanksgiving weekend with nearly 70 million U.S. adults shopping on Black Friday, according to interim results from the Consumer Electronics Association's (CEA)® annual Black Friday Survey, which examines shopping habits, intentions and expectations Thanksgiving Day through Monday, November 26. CEA predicts 120 million U.S. adults will shop during the 2012 Thanksgiving weekend.
The average U.S. consumer who shopped or planned to shop will spend $365 on gifts this weekend. CEA's 19th Annual CE Holiday Purchase Patterns Study, released October 16, 2012, found that consumers plan to spend a total of $842 on all gifts this holiday season.
The most popular day to shop this Thanksgiving weekend was Black Friday, with 29 percent of U.S. adults (69.6 million) indicating they shopped or planned to shop that day. Last year, 27 percent of adults shopped on Black Friday. Saturday was expected to be the next busiest day of the weekend, according to CEA's survey, with 21 percent of adults planning to shop. Shopping on Thanksgiving Day also was up this year. Slightly more than 31 million adults (13 percent) shopped on Thanksgiving, up from 11 percent of U.S. adults last year.
"Shopping is the true American pastime and Black Friday and the days around Thanksgiving are the Super Bowl, World Series and March Madness all rolled into one for shoppers looking for bargains," said Shawn DuBravac, CEA's chief economist and senior director of research. "Consumers plan to use the entire weekend to get a jump start on their holiday shopping to take full advantage of all the deals and discounts."
Consumer electronics (CE) once again was second only to clothes as the most popular items purchased this weekend. Through Friday, 63 percent of those shopping purchased clothing and 47 percent bought electronics. Of those who shopped or planned to shop, more than a third (34 percent) of their total spending will be on electronics with ten percent of all shoppers saying they only purchased or only planned to purchase CE products this weekend.
Mobile connected devices were the most popular electronics purchased through Friday. Among those buying CE, more than a quarter (26 percent) bought a smartphone and 22 percent bought a tablet Thursday or Friday. Headphones (25 percent), portable media players (22 percent) and video game consoles (20 percent) were the next most commonly purchased CE products during the first two days of the long weekend. Other popular CE purchased included e-readers, TVs, digital cameras and accessories.
"CEA's holiday research has consistently shown technology is dominating wish lists so it comes as no surprise that technology stole the show over the weekend," said DuBravac.
The survey found mass merchants were the most popular shopping destination, both overall and for CE products, on Black Friday. Through Friday, 62 percent of consumers doing at least some of their shopping did so at mass merchants. Nearly a quarter (24 percent) say they shopped at a consumer electronics retailer. Among consumers choosing to buy CE in stores on Thursday or Friday, 80 percent did so at a mass merchant. Overall, 82 percent of those buying technology bought something in the store. However, through Friday, 39 percent of CE buyers purchased some electronics online. More than two-thirds of shoppers (68 percent) said stores were as crowded or more crowded than last year, with 25 percent saying they were more crowded. Three-quarters of those who shopped Thursday and Friday said the deals were good to excellent this year.
Cyber Monday will also be a popular day to shop this year. Roughly 35 percent of U.S. adults plan to spend money on holidays gifts with about 16 percent of all spending, on average, taking place on Monday. Roughly 13 percent of consumers (31 million) plan to shop on Cyber Monday.
CEA will host an analyst call with Shawn DuBravac tomorrow, Sunday, November 25 at Noon ET/9am PT. To participate in that call, please dial 1-866-214-0726. The passcode is 794838. On the call, DuBravac will discuss highlights from Black Friday, including how much money consumers spent, what they purchased and where they shopped. DuBravac also will discuss, in more detail, the impact of the fiscal cliff on holiday shopping. For more information, email Steve Kidera at [email protected]. CEA also will host a webinar on Tuesday, November 27 at 2pm ET/11am PT. For more information and to register, click here.
CEA's Black Friday Survey presents the interim findings of a telephone survey conducted among two national probability samples, which, when combined consist of 508 adults, 247 men and 261 women 18-years of age and older, living in the continental United States. The initial interviews were completed on November 23, 2012. Additional data is available with final figures available Monday, November 26. Please cite any information to the Consumer Electronics Association (CEA)®.
About CEA:
The Consumer Electronics Association (CEA) is the preeminent trade association promoting growth in the $206 billion U.S. consumer electronics industry. More than 2,000 companies enjoy the benefits of CEA membership, including legislative advocacy, market research, technical training and education, industry promotion, standards development and the fostering of business and strategic relationships. CEA also owns and produces the International CES – The Global Stage for Innovation. All profits from CES are reinvested into CEA's industry services. Find CEA online at www.CE.org, www.DeclareInnovation.com and through social media: https://www.facebook.com/#!/CEAfeed, http://twitter.com/ceafeed, http://blog.ce.org/.
2013 International CES
January 8-11, 2013, Las Vegas, NV
You think you know what's in your data. But do you? Most organizations are now aware of the business intelligence represented by their data. Data science stands to take this to a level you never thought of – literally. The techniques of data science, when used with the capabilities of Big Data technologies, can make connections you had not yet imagined, helping you discover new insights and ask new questions of your data. In his session at @ThingsExpo, Sarbjit Sarkaria, data science team lead ...
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The IoT has the potential to create a renaissance of manufacturing in the US and elsewhere. In his session at 18th Cloud Expo, Florent Solt, CTO and chief architect of Netvibes, will discuss how the expected exponential increase in the amount of data that will be processed, transported, stored, and accessed means there will be a huge demand for smart technologies to deliver it. Florent Solt is the CTO and chief architect of Netvibes. Prior to joining Netvibes in 2007, he co-founded Rift Technol...
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Join IBM June 8 at 18th Cloud Expo at the Javits Center in New York City, NY, and learn how to innovate like a startup and scale for the enterprise. You need to deliver quality applications faster and cheaper, attract and retain customers with an engaging experience across devices, and seamlessly integrate your enterprise systems. And you can't take 12 months to do it.
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Machine Learning helps make complex systems more efficient. By applying advanced Machine Learning techniques such as Cognitive Fingerprinting, wind project operators can utilize these tools to learn from collected data, detect regular patterns, and optimize their own operations. In his session at 18th Cloud Expo, Stuart Gillen, Director of Business Development at SparkCognition, will discuss how research has demonstrated the value of Machine Learning in delivering next generation analytics to im...
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This is not a small hotel event. It is also not a big vendor party where politicians and entertainers are more important than real content. This is Cloud Expo, the world's longest-running conference and exhibition focused on Cloud Computing and all that it entails. If you want serious presentations and valuable insight about Cloud Computing for three straight days, then register now for Cloud Expo.
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So, you bought into the current machine learning craze and went on to collect millions/billions of records from this promising new data source. Now, what do you do with them? Too often, the abundance of data quickly turns into an abundance of problems. How do you extract that "magic essence" from your data without falling into the common pitfalls? In her session at @ThingsExpo, Natalia Ponomareva, Software Engineer at Google, will provide tips on how to be successful in large scale machine lear...
Apr. 29, 2016 02:45 PM EDT Reads: 864
IoT device adoption is growing at staggering rates, and with it comes opportunity for developers to meet consumer demand for an ever more connected world. Wireless communication is the key part of the encompassing components of any IoT device. Wireless connectivity enhances the device utility at the expense of ease of use and deployment challenges. Since connectivity is fundamental for IoT device development, engineers must understand how to overcome the hurdles inherent in incorporating multipl...
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The paradigm has shifted. A Gartner survey shows that 43% of organizations are using or plan to implement the Internet of Things in 2016. However, not just a handful of companies are still using the old-style ad-hoc trial-and-error ways, unaware of the critical barriers, paint points, traps, and hidden roadblocks. How can you become a winner? In his session at @ThingsExpo, Tony Shan will present a methodical approach to guide the holistic adoption and enablement of IoT implementations. This ov...
Apr. 29, 2016 02:00 PM EDT Reads: 1,545
We've worked with dozens of early adopters across numerous industries and will debunk common misperceptions, which starts with understanding that many of the connected products we'll use over the next 5 years are already products, they're just not yet connected. With an IoT product, time-in-market provides much more essential feedback than ever before. Innovation comes from what you do with the data that the connected product provides in order to enhance the customer experience and optimize busi...
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The IETF draft standard for M2M certificates is a security solution specifically designed for the demanding needs of IoT/M2M applications. In his session at @ThingsExpo, Brian Romansky, VP of Strategic Technology at TrustPoint Innovation, will explain how M2M certificates can efficiently enable confidentiality, integrity, and authenticity on highly constrained devices.
Apr. 29, 2016 02:00 PM EDT Reads: 979
Artificial Intelligence has the potential to massively disrupt IoT. In his session at 18th Cloud Expo, AJ Abdallat, CEO of Beyond AI, will discuss what the five main drivers are in Artificial Intelligence that could shape the future of the Internet of Things. AJ Abdallat is CEO of Beyond AI. He has over 20 years of management experience in the fields of artificial intelligence, sensors, instruments, devices and software for telecommunications, life sciences, environmental monitoring, process...
Apr. 29, 2016 01:30 PM EDT Reads: 791
SYS-CON Events announced today that Ericsson has been named "Gold Sponsor" of SYS-CON's @ThingsExpo, which will take place on June 7-9, 2016, at the Javits Center in New York, New York. Ericsson is a world leader in the rapidly changing environment of communications technology – providing equipment, software and services to enable transformation through mobility. Some 40 percent of global mobile traffic runs through networks we have supplied. More than 1 billion subscribers around the world re...
Apr. 29, 2016 01:00 PM EDT Reads: 770
SYS-CON Events announced today that Stratoscale, the software company developing the next generation data center operating system, will exhibit at SYS-CON's 18th International Cloud Expo®, which will take place on June 7-9, 2016, at the Javits Center in New York City, NY. Stratoscale is revolutionizing the data center with a zero-to-cloud-in-minutes solution. With Stratoscale's hardware-agnostic, Software Defined Data Center (SDDC) solution to store everything, run anything and scale everywhere...
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Angular 2 is a complete re-write of the popular framework AngularJS. Programming in Angular 2 is greatly simplified – now it's a component-based well-performing framework. This immersive one-day workshop at 18th Cloud Expo, led by Yakov Fain, a Java Champion and a co-founder of the IT consultancy Farata Systems and the product company SuranceBay, will provide you with everything you wanted to know about Angular 2.
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You deployed your app with the Bluemix PaaS and it's gaining some serious traction, so it's time to make some tweaks. Did you design your application in a way that it can scale in the cloud? Were you even thinking about the cloud when you built the app? If not, chances are your app is going to break. Check out this webcast to learn various techniques for designing applications that will scale successfully in Bluemix, for the confidence you need to take your apps to the next level and beyond.
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Chris's Reviews > A Storm of Swords
A Storm of Swords (A Song of Ice and Fire, #3)
by George R.R. Martin
by George R.R. Martin
Chris's review
Jan 31, 11
Read from January 25 to 28, 2011
I am still enjoying this series even though I am growing weary of my favorite characters never getting a break (to put it mildly). I kind of skim over the minor players because I still can't keep them straight and enjoy the main flow. Each character could be a book in and of themselves.
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1930-S $10 MS66 NGC. The 1930-S Eagle started out as a ...Click the image to load the highest resolution version.
Premium Gem 1930-S Eagle, Among the Finest Certified1930-S $10 MS66 NGC. The 1930-S Eagle started out as a low mintage issue with just 96,000 pieces produced, but attained its significant rarity similar to the branch mint Twenties from this era when the vast majority was melted into gold bars to line the walls of Fort Knox. Most survivors of the Treasury recall are in Mint State, but few can challenge the lofty preservation of the present premium Gem. The booming luster rolls over nearly undisturbed surfaces, with the only evidence of light contact visible on the Indian's chin and on the UR in PLURIBUS. Sharply struck, only the eagle's back claw has not received a full impression from the dies, since the tip of the lowest headdress feather is absent because of a lightly lapped obverse die. Population: 2 in 66, 2 finer (7/04).
From The John Michael Stuart Collection, Part Two.(#8883) (Registry values: N7079) (NGC ID# 28HA, PCGS# 8883)
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Bulgaria Football Championship Ranked 68th Globally
Sports | January 8, 2013, Tuesday // 17:07| Views: 1031 | Comments: 0
Sports » Be a reporter: Write and send your article Expats.bg All Are Welcome! Join Now!
The A-League of Bulgaria's national football championship has been ranked 68th in the world by the International Federation of Fotball History and Statistics.
The IFFHS ranking is topped by Spain's Primera Division with 1283 points, followed by the top leagues of Brazil (1057 pts), Germany (1037 pts), Italy (1034 pts), and England (1007).
With just 296 pts, Bulgaria is 68th, just behind Northern Ireland, Macedonia, Ghana, Angola and Zimbabwe.
The Bulgarian national football championship is then followed by Venezuela, China and Ireland's first national leagues.
- » Bulgaria's Dimitrov Facing Schwartzman at ATP Istanbul Final
- » Vegan Mountaineer Skatov Also Ascends Annapurna
- » Bulgaria's Boyan Petrov Climbs World's Deadliest Peak
- » Tennis: Grigor Dimitrov Reaches ATP Istanbul Final
- » Bulgaria's Grigor Dimitrov Reaches Semifinals in Istanbul
- » Stiliyan Petrov Could Also Return to Bulgaria's National Football Team
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- Generation Emigration
- May 3, 2016, 00:41
Noelle O'Connell is executive director of European Movement Ireland, which is running a campaign to encourage Irish people in Britain to register to v(...)
UK stands to gain little tax benefit in event of Brexit
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- April 18, 2016, 15:38
The debate on a British exit from the European Union is deep-rooted in sovereignty. It is about the control the UK has over its own laws and regulatio(...)
Brexit: Any bid for Border controls 'unacceptable' - SF
- Politics
- April 11, 2016, 18:59
Sinn Féin has warned any attempt to introduce Irish Border controls would be "a major setback for the political process in the North". Sinn Féin MEP (...)
Brexit is a threat to UK-Irish relations, says British ambassador
- Irish News
- April 4, 2016, 22:03
Britain exiting the European Union would reduce the contact between Irish and British politicians and officials that takes place in Brussels and woul(...)
The 'true' republicans: 'Nothing since 1919 is legitimate'
- Irish News
- March 26, 2016, 01:00
The rooms in Republican Sinn Féin's offices on Parnell Street in Dublin are filled with a chaotic clutter, a mass of agitprop paraphernalia stuffed in(...)
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- Europe
- February 15, 2016, 18:12
What is Brexit? The countdown has begun to the United Kingdom's referendum on withdrawal from the European Union. The stakes are high: if UK voters o(...)
No second Brexit vote in event of 'wrong answer', ambassador says
- February 10, 2016, 19:00
The British government will not hold a second referendum on the UK's membership of the European Union "if the people deliver the wrong answer" in the (...)
Enlargement and the euro - two big mistakes that ruined Europe
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- November 2, 2015, 07:36
There has hardly been a year when the EU has not been on the brink of some crisis: banking, sovereign debt, Russia's annexation of Crimea and now ref(...)
Janan Ganesh: Fudge is good for Britain and Europe
- October 13, 2015, 01:01
Meant to wound, "Perfidious Albion" sometimes feels like a backhanded compliment. The world can see that Britain has done well out of its reluctance t(...)
Jimmy O'Mahony – senior civil servant who smoothed Ireland's path into EEC
- People
- October 10, 2015, 01:00
For someone whose work had a considerable impact on the nation's economic life, Jimmy O'Mahony, who has died aged 90, remained very much below the rad(...)


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Joplin Angela Vorhees Law
1. Angela Austin Vorhees
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