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Article: The Pharmacogenetics of Major Depression: Past, Present, and Future
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COMMENTARYThe Pharmacogenetics of Major Depression: Past,Present, and FutureGonzalo Laje and Francis J. McMahonMpatients, maximizing efficacy while minimizing—or eliminat-ing—adverse effects. This vision has been widely embraced outof a real desire to better help patients. But we are now someyears into the pharmacogenetics enterprise, and we are begin-ning to accumulate real-world data in juxtaposition to ourperhaps somewhat idealistic expectations. Some of the assump-tions underlying the vision are beginning to be scrutinized moreclosely. Can we really match medications with patients when therange of available treatments is still quite small compared withthe range of clinical presentations? Can genetics really providethe keys? How much of the difference between patients inefficacy and adverse effects will actually be attributable todifferences in life experience and circumstances that we canneither measure biologically nor address medically? The techno-logical advances of human genetics over the past decade, alongwith the recent availability of large treatment cohorts for study,are beginning to answer these questions. Pharmacogenetics isbeing transformed from a small field of promising leads into oneof the foundations of evidence-based medicine. Few specialtiesstand to benefit as much as psychiatry, where all of our treatmentoptions are empirical and the matching of patients with treat-ments is largely a question of clinical judgment.The pursuit of genetic markers that can help predict responseto treatment or important adverse events has been the focus ofmany investigations but so far has led to few clinical applications(1). This may be changing, as specific genetic association find-ings gain validity. Recently, the U.S. Food and Drug Administra-tion added pretreatment genetic testing to the prescribing infor-mation for the anticoagulant drug warfarin, which has a narrowtherapeutic index. About 40% of the variance in warfarin dose isattributable to variation in cytochrome P450 and vitamin Kmetabolism genes (2).Major depression, which is predicted to be the second leadingcause of death and disability by the year 2020 (3), is an idealtarget for pharmacogenetic approaches (4). Although manytreatments exist, initial response rates are stuck at about 50%, andonly a minority of patients fully remit (5). Choosing the besttreatment for each patient is difficult, and clinical predictors ofdifferential response are scarce (6). Although adverse events areuncommon in the age of selective serotonin reuptake inhibitors(SSRIs), concern about some adverse events, such as treatment-emergent suicidality, may reduce access to, and acceptability of,treatment (7). In the face of all this, good genetic markers oftreatment outcome in major depression might have immediateuch has been said and written in recent years about thepromise of pharmacogenetics. The vision is one of aworld where we will be able to match medications withclinical relevance—yet in many ways, the search for suchmarkers has barely begun.Here, we address some of the past history, ongoing research,and near future of pharmacogenetic studies of major depression.Rather than attempt a comprehensive review of the literature,which has already been done well in some recent papers (4,8),we aim to highlight some of the key issues facing the field andsketch a vision for the future. Throughout, we use the termpharmacogenetic rather than the grander pharmacogenomic butconsider both terms synonymous.The Past: Small Samples and Few GenesA MEDLINE search using the terms pharmacogenomics orpharmacogenetics and depression in humans yields about 100articles, almost half of which are labeled as reviews. This wouldsuggest that since 1968, the year of the first cited article, muchhas been written but not as much new information has beenacquired. This characterization is not confined to the pharmaco-genetics of major depression; it applies almost as well to thepharmacogenetics of other fields. In retrospect, without many ofthe necessary genetic tools and large samples to study, rapidprogress could hardly have been expected.Faced with these limitations, past approaches have beengeared toward a limited number of markers in a small fraction ofthe ?20,000 human genes. These include genes in the cyto-chrome P450 system, a major pathway of drug metabolism, andgenes involved in the production, release, binding, and reuptakeof monoamines, especially the serotonin transporter (SERT).Only the P450 genes have found a clinical application and thishas been so far quite limited (1), probably owing to the declinein the use of tricyclic antidepressants, the information that comesdirectly from a careful medication history, and the clinically smalleffects of the P450 system on the most widely prescribed SSRIs.The serotonin transporter and a functional polymorphism inits promoter region (known as the linked polymorphic region[LPR]) have received the most attention by researchers. Theserotonin transporter is undoubtedly the proximal target for theSSRIs and the LPR seems to affect gene expression in importantways (9), but consistent association with SSRI response has beendifficult to demonstrate. A recent meta-analysis of 15 publishedstudies concluded that there was evidence in favor of a significantassociation of the L-allele with better response to SSRIs (10). Thisresult may reflect publication bias—since there is a lack of evensmall studies that report an effect size below the pooled oddsratio—but may be consistent with a true effect of the SERT LPR ontreatment outcome. Recent studies, reviewed below, suggest thatgenetic variation in the SERT LPR has an impact on SSRI-related sideeffects. This might explain some of the outcome findings.The Present: Picking Up SpeedThere have been two big developments in recent years thathave greatly accelerated progress in the field: the availability oflarge, well-characterized samples and the advent of genomictechnologies of unprecedented power and efficiency. The Se-quenced Treatment Alternatives to Relieve Depression (STAR*D)From the Genetic Basis of Mood and Anxiety Disorders Unit, Mood andAnxiety Program, National Institute of Mental Health, Bethesda, Mary-land.Address reprint requests to Francis J. McMahon, M.D., 35 Convent Drive,Room 1A202, Bethesda, MD 20892-3719; E-mail: email@example.com September 18, 2007; accepted September 19, 2007.BIOL PSYCHIATRY 2007;62:1205–1207© 2007 Society of Biological Psychiatry0006-3223/07/$32.00doi:10.1016/j.biopsych.2007.09.016
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study (11) has for the first time provided a sample of well-characterized patients large enough to detect even modestgenetic effects. Although not designed specifically to answerpharmacogenetic questions, STAR*D provides DNA from a clin-ically representative cohort of about 2000 adults with majordepression, all treated with citalopram for at least 6 weeks andevaluated prospectively for treatment response, remission, andadverse events. Patients who failed to respond adequately to theinitial treatment were switched to a variety of other treatments.The large size of the uniformly treated sample is crucial, since itrepresents an order-of-magnitude increase over all previouslystudied samples with major depression. Large samples are a keyelement of robust genetic association findings (12).Candidate gene association studies in the STAR*D samplehave already begun to uncover alleles associated with citalopramresponse and adverse events such as treatment-emergent suicidalideation (13–17). The published effect sizes for the response-associated alleles are modest, with odds ratios on the order of 1.5to 1.7. The effect sizes for the adverse event associations appearto be larger, but the true effect sizes cannot, of course, beaccurately estimated in a single sample. In any case, effect sizeswill need to be much larger if genetic markers are to help guidetreatment decisions. Such effect sizes might be achievable withmultimarker, multigene tests, but this remains to be seen.The results in the large STAR*D sample have also begun toclarify some of the questions concerning the role of the SERTLPR: while there is no convincing evidence for association withtreatment response in the STAR*D sample (18), the data suggestthat a novel functional allele related to the traditional S-allele isassociated with perceived side-effect burden (13). This resultmight have been mistaken for an association with treatmentresponse if side effects had not been considered, since patientswith a high side-effect burden may not be able to take a sufficientdose of medication to achieve a good response.The second big development has been the new technologiesthat allow the screening of genome-wide sets of genetic markers.These technologies have opened the door for genome-wideassociation (GWA) studies that use large numbers of singlenucleotide polymorphism (SNP) markers (now 500,000 to1,000,000) to screen the entire genome for alleles that influencea trait of interest. For pharmacogenetics, this is a crucial advance,since it transcends candidate gene studies, which are limited bythe genes chosen, and supplants linkage methods, which requirefamilies and are impractical for most pharmacogenetic questions.At least two GWA studies of antidepressant treatmentoutcome are currently underway. Each has interrogated over300,000 markers. The results of these studies will provide themost comprehensive view to date of genetic influences onantidepressant response. However, GWA studies are usuallyunderpowered to detect alleles of small effect. If antidepressanttreatment outcome is influenced by many genes, each of smalleffect, which seems likely, then GWA studies may miss many ofthem. Alternatively, such genes may be implicated by markerswith modest effects (and statistical significance), the importanceof which may only be recognized after several replications andthe demonstration of functional alleles. Additional large samplesof uniformly treated and longitudinally assessed patients willthus be essential for validating the results of the GWA studiesalready underway.The Future: Knocking at the Clinic DoorSince the recent publication of the first Encyclopedia of DNAElements (ENCODE) data (19), it has become clear that protein-coding genes are only a very small part of the genome and thatmost human DNA has significant biological activity: there may beno "junk" DNA. Until we fully understand the mechanisms thatregulate gene function, we should maximize the results weobtain from available samples. Near-future technology can addsignificant amounts of information to what we already have. Inaddition to ever denser genome-wide sets of SNP markers, suchas the million SNP chips that are already coming into use,ultra-high throughput sequencing technology may make thecomplete genome sequence a standard part of each patient'smedical record. This will pose an enormous challenge to clini-cians, who will need to interpret this large quantity of data forpatients and their families.It is also likely that single nucleotide polymorphisms are notthe sole genetic regulators of antidepressant response. We willneed to interrogate other types of variation such as copy numberpolymorphisms and epigenetic signatures. Accumulating evi-dence demonstrates that copy number polymorphism is a com-mon source of human genetic variation that may have majoreffects on gene function (20). Epigenetic variation—heritablechanges in gene expression that are influenced by parent-of-origin and environmental factors—is another previously unrec-ognized but important source of human genetic variation. Earlyfindings suggest that antidepressant medications affect epige-netic signatures, and agents that modify epigenetic signaturescan exert antidepressant effects (21).In addition to novel genetic investigations, the future ofpharmacogenetics in mood disorders will depend heavily on theavailability of large, well-characterized samples. Along withfrequent, prospective assessment during treatment, these sam-ples should ideally provide a detailed clinical and diagnosticpicture that reflects both current and prior episodes, along withmedication history, ethnic background, and psychosocial history.The latter may be an important source of individual differences intreatment outcome owing to temperament, resilience, and thecumulative impact of adverse life events (22). Although directinformation on in vivo gene expression in the brain may bebeyond the reach of near-future technology, neuroimaging tech-niques such as positron-emission tomography (PET) or magneticresonance spectroscopy (MRS) may provide valuable data on theimpact of antidepressant medications on brain chemistry in vivo.In summary, the next decade should bring significantprogress for pharmacogenetics in psychiatry. This progress willrequire a significant effort in sample collection, genetic assays,and clinical validation. For the promise of clinically useful toolsto be realized, the field must produce clinically meaningfulfindings and not just statistically significant associations. If wesucceed, the payoff will be big: more personalized care, moreeffective medications, fewer adverse events, and a reduction inthe burden of mood disorders for both patients and society.Supported by the Intramural Research Program of NationalInstitute of Mental Health (NIMH), National Institutes of Health(NIH), U.S. Department of Health and Human Services (DHHS),and by the National Alliance for Research on Schizophrenia andDepression (NARSAD). The content of this publication does notnecessarily reflect the views or policies of the Department ofHealth and Human Services, nor does mention of trade names,commercial products, or organizations imply endorsement bythe U.S. Government.The authors report no competing interests.1206 BIOL PSYCHIATRY 2007;62:1205–1207Commentarywww.sobp.org/journal
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1. Swen JJ, Huizinga TW, Gelderblom H, de Vries EG, Assendelft WJ, Kirch-heiner J, et al. (2007): Translating pharmacogenomics: Challenges onthe road to the clinic. PLoS Med 4:e209.2. WadeliusM,ChenLY,DownesK,GhoriJ,HuntS,ErikssonN,etal.(2005):Common VKORC1 and GGCX polymorphisms associated with warfarindose. Pharmacogenomics J 5:262–270.3. Murray CJ, Lopez AD (1996): Evidence-based health policy—lessonsfrom the Global Burden of Disease Study. Science 274:740–743.4. Perlis RH (2007): Pharmacogenetic studies of antidepressant response:How far from the clinic? Psychiatr Clin North Am 30:125–138.5. TrivediMH,RushAJ,WisniewskiSR,NierenbergAA,WardenD,RitzL,etal.(2006):Evaluationofoutcomeswithcitalopramfordepressionusingmeasurement-based care in STAR*D: Implications for clinical practice.AmJPsychiatry163:28–40.6. Nierenberg AA (2003): Predictors of response to antidepressants: Generalprinciplesandclinicalimplications.PsychiatrClinNorthAm26:345–352.7. Gibbons RD, Brown CH, Hur K, Marcus SM, Bhaumik DK, Erkens JA, et al.(2007): Early evidence on the effects of regulators' suicidality warningson SSRI prescriptions and suicide in children and adolescents. Am JPsychiatry 164:1356–1363.8. Binder EB, Holsboer F (2006): Pharmacogenomics and antidepressantdrugs. Ann Med 38:82–94.9. LeschKP,BengelD,HeilsA,SabolSZ,GreenbergBD,PetriS,etal.(1996):Associationofanxiety-relatedtraitswithapolymorphismintheseroto-nin transporter gene regulatory region. Science 274:1527–1531.10. SerrettiA,KatoM,DeRD,KinoshitaT(2007):Meta-analysisofserotonintransporter gene promoter polymorphism (5-HTTLPR) association withselective serotonin reuptake inhibitor efficacy in depressed patients.MolPsychiatry12:247–257.11. RushAJ,FavaM,WisniewskiSR,LavoriPW,TrivediMH,SackeimHA,etal.(2004): Sequenced treatment alternatives to relieve depression(STAR*D): Rationale and design. Control Clin Trials 25:119–142.12. IoannidisJP,TrikalinosTA,NtzaniEE,Contopoulos-IoannidisDG(2003):Genetic associations in large versus small studies: An empirical assess-ment. Lancet 361:567–571.13. HuXZ,RushAJ,CharneyD,WilsonAF,SorantAJ,PapanicolaouGJ,etal.(2007): Association between a functional serotonin transporter pro-moter polymorphism and citalopram treatment in adult outpatientswith major depression. Arch Gen Psychiatry 64:783–792.14. Laje G, Buervenich S, Manji H, Rush AJ, Wilson AF, McMahon FJ (2007):Genetic markers of suicidal ideation emerging during antidepressanttreatment.AmJPsychiatry164:1530–1538.15. McMahonFJ,BuervenichS,CharneyD,LipskyR,RushAJ,WilsonAF,etal.(2006): Variation in the gene encoding the serotonin 2A receptor isassociatedwithoutcomeofantidepressanttreatment.AmJHumGenet78:804–814.16. PaddockS,LajeG,CharneyD,RushAJ,WilsonAF,SorantAJ,etal.(2007):Association of GRIK4 with outcome of antidepressant treatment in theSTAR*Dcohort.AmJPsychiatry164:1181–1188.17. PerlisRH,PurcellS,FavaM,FagernessJ,RushAJ,TrivediMH,etal.(2007):Associationbetweentreatment-emergentsuicidalideationwithcitalo-pram and polymorphisms near cyclic adenosine monophosphate re-sponse element binding protein in the STAR*D study. Arch Gen Psychi-atry 64:689–697.18. Kraft JB, Peters EJ, Slager SL, Jenkins GD, Reinalda MS, McGrath PJ,et al.(2007): Analysis of association between the serotonin transporter andantidepressant response in a large clinical sample. Biol Psychiatry 61:734–742.19. Birney E, Stamatoyannopoulos JA, Dutta A, Guigo R, Gingeras TR, Mar-guliesEH,etal.(2007):Identificationandanalysisoffunctionalelementsin 1% of the human genome by the ENCODE pilot project. Nature447:799–816.20. FeukL,CarsonAR,SchererSW(2006):Structuralvariationinthehumangenome.NatRevGenet7:85–97.21. DumanRS,NewtonSS(2007):Epigeneticmarkingandneuronalplastic-ity. Biol Psychiatry 62:1–3.22. Nemeroff CB, Vale WW (2005): The neurobiology of depression: In-roads to treatment and new drug discovery. J Clin Psychiatry66(suppl 7):5–13.CommentaryBIOL PSYCHIATRY 2007;62:1205–1207 1207www.sobp.org/journal


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What Milwaukee is talking about
Today's Only in America story
Is this a great country, or what? The Salahis, known throughout the world as the White House gate crashers, may be getting their own reality show. Sure, they're under federal investigation. But that will make the show even better, right?
Tiger Woods, meanwhile, is eating cereal and watching cartoons. And hitting a few golf balls. His wife, Elin, is reportedly going to sue for divorce.
In Poland, someone has stolen the infamous "Work Will Make You Free" sign in front of the Auschwitz death camp.
Out in Los Angeles, columnist Bill Plaschke is now convinced that Kobe Bryant, who hit a buzzer-beater to beat the Milwaukee Bucks on Wednesday, "can do anything." If you're a Bucks fan, you might add, "do anything after a horrible call that allowed Bryant to hit that buzzer beater in the first place." But Bucks' fans aren't bitter, are they?
And remember Cher? She's doing fine, thanks. But she's auctioning off a home she built in Hawaii that she never lived in. Same thing happened to you? Didn't think so. She expects to get at least $8 million for property.
Comments »
Read and share your thoughts on this story.

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VIVE events take place at various locations throughout the year and are organized by local Evangelical Covenant Church congregations.
Registration is free, but we do request that you sign up online in advance to assist our local event coordinators. We encourage youth leaders to register all of their students at once in order to streamline the process; you can also modify your order (e.g., add or remove registrants) after you've registered.
Eagle Rock Covenant Church
1649 Yosemite Drive
Los Angeles, CA 90041
For more information, please email local event coordinator Lynda Delgado.
Congregational Resources:
The VIVE Bay Area is hosting two events on May 16. When registering, please select either the morning or afternoon event:
South Bay Community Church
47385 Warm Springs Blvd.
Fremont, CA 94539
For more information, please email local event coordinator Lynn Lockett.
Contact Us by Phone
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The Microsoft Dynamics CRM Team Blog
News and views from the Microsoft Dynamics CRM Team
A corporate blog is an interesting beast. One has to refrain from giving 'irresponsible advice' and yet one has also 'speak in a human voice'. Reflecting back on our own team blog we have certainly made a few mistakes along the way. We accidently published some unsupported customizations (and quickly clarified the mistake), a few of our posts are too long, others read like they were written by robots etc. Overall I think our team has done a decent job with experimenting with this new medium. Soon (I can't/won't say when) we will start talking about Titan on the blog. I'm considering a major strategy change for the blog to coincide with this momentous event.
Feel free to praise/flame us in the comments or feel free to email me directly (my email is easy to find on the internet). With any luck our blog won't end up like the fictional Playstation Blog imagined by Penny Arcade. Tell us what interests you: Design ideas, code samples, pictures of our pets, team profiles, feature suggestions, marketing info, more community guest bloggers etc etc.
Philip Richardson
Inside info :-) I mean it - why not say: we do now this and this, we think this is good, we have no time to do this, but it is good idea, maybe later. We had dilemma with this and have decided this because of this. Info about community projects (if there are some). No marketing, no pets.
Only praise here. You guys have done a great job posting info on this blog and it has added a great deal of value to me personally and our organization.
Please keep it up!!
Pues la r espuesta es pronto . Ayer Philip Richardson (Program Manager) hacía una pequeña reflexión sobre
Always like the "ideas" generated on how-to's within CRM. Undocumented features and yes, even the "unsupported" stuff - when fully explained as such - are welcome.
I like the information but I have to say that I want more. Understanding that probably ever major install has some "unauthorized or unsupported" change, explaining how to accomplish some of those things within the framework of supported changes, would be a great thing.
One easy example, quick creates, MS supports allowing for new acccounts and contacts via quick creates out fo the box but for customer service quick create cases is just if not more important. We had to do an unauthorized update to prevent close to a dozen additional steps for users.
Also linking the regional CRM blogs to the main blog site would be good. The combination of this main blog and the regional ones has helped me modify our CRM solution to make life easier on our users, so please keep up the good work.
I'm glad to read this message. It's important for me to know about the new version. I'm interested in new features (multilanguage, more flexible form designer, more relationship options, field level permission, ... ?? ), and in new architecture.
This is a very useful blog. It could be enhanced by including more information on what is coming up in rollups / new versions. This makes the planning process easier for IT departments, e.g. should I buy an add-in now, or is the feature I am looking for about to come out in a couple of months.
Another example is update rollup 2 has been mentioned with a release date of a few weeks ago, but nothing has been said since about when the release is now expected nor any ideas what it contains.
The blog is an awesome has done a great job at providing much needed info from the product team. Negative feedback would be as follows -- various guest bloggers should in my opinion stick to their own blogs anyone interested in following CRM follows a number of blogs anyway. If the blog is short on subjects for a given week – please keep it simple and don't post anything -- If I want to read about Dundas controls or All things digital I can find that on other blogs.. If I want to know what it's like to be an MVP I will find that info on an MVP blog – this is the internet not a TV channel
In short my feedback and ask is that this blog is kept a clean CRM product blog – a blog whereon we find the hard to get info on CRM from the product team.


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Standard Interpretations - Table of Contents
| Standard Number:
November 14, 1996
Mr. Bill Pollard
P.O. Box 2181
Pasco, Washington 99302
Dear Mr. Pollard:
This is in response to your letter which was faxed to our office on September 3, regarding compressed gas cylinders. We apologize for the delay in our response.
Your letter indicated the following: "An instrumentation trailer is to be relocated to remote sites and used intermittently. And then, it is returned to a central location and placed in a standby status for periods of one to several weeks. The trailer contains analytical chemistry instruments and two or three compressed gas cylinders."
"One 57" x 10" cylinder of compressed air, approximately 200 cubic feet capacity, is secured adjacent to a similar sized hydrogen cylinder. The cylinders each have site regulators and supply lines connected to analytical chemistry instruments."
Please find in the following your specific questions and our responses.
Q1: In inactive standby status the cylinders are "connected for use" but will not be in use until they are dispatched to the next job location. The "inactive standby" intervals will vary from one to several weeks. Should the hydrogen and/or compressed air cylinders be "placed into storage" (removed from the trailer) during standby, and if so, after what time has elapsed?
A1: The careful review of the Compressed Gas Association Pamphlet (P-1, 1965) revealed that for safe handling, cylinders that are not in use should be placed into storage. That is, when the cylinders are not in use, they should be capped for valve protection. It is suggested that during standby status, the regulators of the cylinders be removed. In addition, the cylinders should be securely attached to a fixed object to prevent the movement of the cylinders. Please refer to P-1, 1965, Section 3.3, "Storing Cylinders."
The provisions in that section are to prevent the accidental movement, discharge, etc., of the compressed gases. You did not indicate that any other activity takes place in the trailer. If that is so, adherence to the provisions in the pamphlet should make storage in the trailer acceptable, while the cylinders are not in use. We see no reason to remove the cylinders from the trailer, as long as unauthorized users are prevented from entering the trailer. Also, please note all safe handling procedures for storage of hydrogen in 29 CFR 1910.103, as well as all other provisions for compressed gases in P-1, 1965.
Q2: I understand that OSHA views breathing air cylinders the same as oxygen cylinders. If this interpretation is correct, is there an interpretive reference?
A2: It is not clear whether this question pertains to the integrity of the cylinders, as well as storage and handling procedures, or the quality of the air contained in the cylinders.
Please note that OSHA provides free compliance consultation through its area offices and for small employers, through state-run consultation services, and this may assist with questions to which we may be unable to respond due to lack of information, or on a need to see what is in place. Please call for further assistance with this question.
As you may know, the State of Washington administers its own occupational safety and health program under the state plan provisions of the Occupational Safety and Health Act of 1970. As part of that program, the state is required to have standards at "least as effective as" the federal standards; therefore, you should contact the state of Washington for information on its equivalent standard, if the workplace is in the state of Washington. In the state of Washington, you should contact the following:
Mark O. Brown, Director Washington Department of Labor And Industries General Administration Building P.O. Box 44000 Olympia, Washington 98504-4000 Telephone: (360)902-5495
Thank you for your inquiry. If you need further assistance, please contact Alcmene Haloftis of my staff at 202-219-8031.
John B. Miles, Jr., Director
Directorate of Compliance Programs
|Standard Interpretations - Table of Contents
The Department of Labor does not endorse, takes no responsibility for, and exercises no control over the linked organization or its views, or contents, nor does it vouch for the accuracy or accessibility of the information contained on the destination server. The Department of Labor also cannot authorize the use of copyrighted materials contained in linked Web sites. Users must request such authorization from the sponsor of the linked Web site. Thank you for visiting our site. Please click the button below to continue.


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Services for behavioral health in North Carolina mirror shortages that are found in the rest of the country. According to the federal government's last count in 2013, thirty-six of the state's 100 counties are designated as Mental Health Professional Shortage Areas (HPSA), and another report estimates 28 counties are without a psychiatrist.
Martha Whitecotton, senior vice president for Behavioral Health at CHS says the organization is providing a behavioral health team to its primary care practices for a couple of reasons. One is that patients are less likely to feel the societal stigma of mental illness in their primary care doctor's office.
Equipping Physicians
Another important, and potentially overlooked reason, is that while primary care doctors often prescribe medications addressing common behavioral health conditions, such as anxiety and depression, physicians are not adequately supported to initiate a conversation about mental healthcare and/or follow up with those patients.
"When a patient does speak up to their primary care doctor, if intervention doesn't happen, no one knows it doesn't happen," Whitecotton told me.
And if there is no intervention, the likelihood of a crisis with that patient increases. Those crises can be scary for the patient, their families, and the public.
Comments are moderated. Please be patient.


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Lil' Eclair Bulks Out by Wobbleblot-AltWatch
©2013-2016 Wobbleblot-Alt
Eclair all bulked out.
Anyways, hope you all enjoy!
Anyways, hope you all enjoy!
Time to go super saiyan! Haaaaaaaaaaaaaaaaaaa!
Very nice work!
...T many steroids?
muscle girl+a bandana=life threatening levels of hornyness on my end
nice job
so beautyful <3
Oh my.
yaaaaaaay as usual gettin awesomer.
Thanks, glad you think so. :3
dunno if I forgot to ask but are requests possible at this point? Cus Im all interested an stuff
can't wait to see her when she's older
She can get bigger...
*3* awsome body, but I like more her face expression XD
Wow, I never thought Eclair could be bigger. Fortunately I was wrong. Good work friend.
So adorable!
lil' Eclair? There ain't nothing little about that girl!
mmm i love it XD
She is a friggin' leviathan at this point already O_O Would be awkward to be her babysitter if she needed one sometime XD
Just as long as they didn't want to want to do anything perverted with her, they would be relatively safe. XP
Naah. I was only meanin' the part about her needin' bein' guarded... even if she is such a little mountain of muscle that could likely crush an adult man like nothing. And the fact that a kid's bigger than ya X3
Getting better everyday, mam!
Very impressive!! Especially with the light effects!!!
Beautiful. If only she had the determination to push herself further. Now I'm curious to see what other girls she's met within this program


text:
125 search results for Justin Lin
Simon Pegg on what Justin Lin will bring to 'Star Trek 3'
Type: Video | Date: Tuesday, Apr 21, 2015Simon Pegg admires Justin Lin's independent films and his work in with the 'Fast and Furious' franchise.
'True Detective' may get Justin Lin to direct 2 episodes
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Should a new 'Star Trek' TV series worry fans of the ongoing movie series?
Type: Post | Date: Monday, Nov 2, 2015Can they sustain two ongoing series at the same time?
Why Justin Lin makes sense as the new director of 'Star Trek 3'
Type: Post | Date: Tuesday, Dec 23, 2014And why studios are starting to gamble more than ever
Star Trek Beyond - Trailer #1
Type: Video | Date: Monday, Dec 14, 2015
True Detective - Season 2 Trailer #1
Type: Video | Date: Wednesday, Jun 17, 2015The disappearance of a city manager disrupts a lucrative land scheme and ignites an investigation involving three police officers and a career criminal who is moving into legitimate business.
Fast & Furious 6 - Justin Lin Interview
Type: Video | Date: Saturday, May 18, 2013Director Justin Lin talks leaving the Fast & Furious franchise on a high note in this interview with Guy Lodge. Lin goes on to describe his transition from the independent film world.
Justin Lin won't direct 'Fast & Furious 7'
Type: Article | Date: Thursday, Apr 4, 2013Series vet cites timing as reason for exit from lucrative franchise
'Fast & Furious' vet Justin Lin will direct next 'Bourne' film
Type: Article | Date: Friday, Nov 8, 2013Jeremy Renner will return as Aaron Cross
10 Stories You Might Have Missed: Will 'Fast & Furious'' Justin Lin direct a 'Community' movie?
Type: Gallery | Date: Saturday, Mar 29, 2014Six seasons and a "Fast & Furious" movie? NBC's acclaime...


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The Investor Relations pages are designed to provide all investors and the capital markets with precise, equable and reliable information. Norwegian presents financial data through its quarterly reports and presentations, as well as a monthly traffic development report.
Our investor relations section is published in English only.
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Book your room at Sheraton Albuquerque Airport Hotel
Traditional Room, 1 King BedMax Occupancy: 3 guests (up to 2 children)
Traditional Room, 2 Queen BedsMax Occupancy: 4 guests (up to 3 children)
Club Room, 1 King Bed, Business Lounge AccessMax Occupancy: 3 guests (up to 2 children)
Club Room, 2 Queen Beds, Business Lounge AccessMax Occupancy: 4 guests (up to 3 children)
Get an overview of this hotelAlbuquerque Airport Hotel with 24 hour airport shuttle
When you stay at Sheraton Albuquerque Airport Hotel in Albuquerque, you'll be connected to the airport and close to Puerto Del Sol Golf Course and National Hispanic Cultural Center.
This hotel is within close proximity of University Stadium and Isotopes Park.
Make yourself at home in one of the 276 air-conditioned rooms featuring flat-screen televisions. Cable programming provides entertainment, and wired and wireless Internet access is available for a surcharge. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include desks and coffee/tea makers, and housekeeping is provided daily.
Enjoy recreational amenities such as an outdoor pool and a fitness center. This hotel also features wireless Internet access (surcharge), concierge services, and gift shops/newsstands.
Grab a bite to eat at the hotel's restaurant, which features a bar, or stay in and take advantage of room service (during limited hours). Quench your thirst with your favorite drink at a bar/lounge. Breakfast is available for a fee.
Featured amenities include high-speed (wired) Internet access (surcharge), a business center, and a computer station. Event facilities at this hotel consist of a conference center, conference space, and meeting rooms. A roundtrip airport shuttle is complimentary (available 24 hours), and a train station pick-up service is also provided at no charge.Information missing or incorrect? Tell us!Opens in a new window
Hotel Amenities
Hotel Amenities
Sheraton Albuquerque Airport Hotel features an outdoor pool and a fitness facility. Dining options at the hotel include a restaurant. A bar/lounge is on site where guests can unwind with a drink. This 3.5-star property offers access to a business center and audio-visual equipment. Event facilities include conference/meeting rooms and banquet facilities. This business-friendly hotel also offers concierge services, complimentary newspapers in the lobby, and dry cleaning/laundry services. An area shuttle within 2 mi based on availability and a roundtrip airport shuttle (available 24 hours) are complimentary for guests. Complimentary parking is available on site. A total renovation of this property was completed in 2011. Sheraton Albuquerque Airport Hotel is a smoke-free property.
- Computer station
- Luggage storage
- Laundry facilities
- Television in common areas
- Free train station pickup
- 24-hour front desk
- Free airport transportation
- ATM/banking
- Number of floors - 15
- Bar/lounge
- Breakfast available (surcharge)
- Business center
- Free newspapers in lobby
- Concierge services
- Conference space
- Dry cleaning/laundry service
- Elevator/lift
- Express check-in
- Express check-out
- Fitness facilities
- Gift shops or newsstand
- WiFi (surcharge)
- Wired (high-speed) Internet access - surcharge
- Meeting rooms
- Multilingual staff
- Total number of rooms - 276
- RV, bus, truck parking
- Porter/bellhop
- Restaurant
- Safe-deposit box at front desk
- Long-term parking (surcharge)
- Self parking (surcharge)
- Number of meeting rooms - 10
- Conference center
- Smoke-free property
- Outdoor pool
- Wedding services
Family Friendly Amenities
- Family Hotel
- Outdoor pool
- Rollaway/extra beds available
- Laundry facilities
- Refrigerator (on request)
- Microwave (on request)
- Cribs/infant beds (complimentary)
Available in all rooms: Wireless internet access ( 12.95 USD per day ), Wired internet access ( 12.95 USD per 24-hour period )
Available in some public areas: Wireless internet access ( 12.95 USD per 24-hour period ), Wired high-speed internet ( 12.9.5 USD per 24-hour period )
Long-term parking (surcharge), Self parking (surcharge), RV, bus, truck parking
Room Amenities
- Premium TV channels
- Pay movies
- Hypo-allergenic bedding available
- Premium bedding
- Air conditioning
- Climate control
- Free bottled water
- Coffee/tea maker
- Microwave (on request)
- Refrigerator (on request)
- Daily housekeeping
- Turndown service
- Private bathroom
- Hair dryer
- Shower/tub combination
- Iron/ironing board
- Desk
- Rollaway/extra beds available
- Cable TV service
- WiFi (surcharge)
- Wired high-speed Internet access (surcharge)
- Free toiletries
- Room service (limited hours)
- Free cribs/infant beds
- Rollaway/extra beds (surcharge)
- Flat-panel TV
Where to Eat
Sheraton Albuquerque Airport Hotel has a restaurant on site. Room service (during limited hours) is available.
Nearby Things to Do
Recreational amenities at the hotel include an outdoor pool and a fitness facility. The recreational activities listed below are available either on site or nearby; fees may apply.
- Golfing nearby
- Downhill skiing nearby
- Hiking/biking trails nearby
- Mountain biking nearby
To make requests for specific accessibility needs, complete the "Special or Accessibility Requests" section of "Trip Preferences" when you book your hotel.
- Accessible bathroom
- In-room accessibility
- Roll-in shower
Hotel Policies
Check-in time ends at 5:30 AM
Check-in time starts at 3 PM
Minimum check-in age is 21
Check-out time is noon
Payment types
Pets allowed, Only dogs are allowed, Maximum number of pets per room 2, Pet maximum weight in lb is 40
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
Service animals exempt from fees/restrictions
- Pet deposit: USD 25.00 per day
Optional extras
- Breakfast fee: USD 8 per person (approximately)
- Fee for in-room wireless Internet: USD 12.95 per day (rates may vary)
- Fee for in-room high-speed Internet (wired): USD 12.95 per 24-hour period (rates may vary)
- Fee for wireless Internet in public areas: USD 12.95 per 24-hour period (rates may vary)
- Fee for high-speed Internet (wired) in public areas: USD 12.9.5 per 24-hour period (rates may vary)
- Self parking fee: USD 5.00 per day (in/out privileges)
- Pet fee: USD 25 per pet, per stay
- Refrigerator fee: USD 15.00 per stay
- In-room microwave fee: USD 15.00 per stay
- Rollaway bed fee: USD 15.00 per day
Hotel Name
- Albuquerque Airport Hotel
- Albuquerque Airport Sheraton
- Sheraton Albuquerque Airport
- Sheraton Albuquerque Airport Hotel
- Sheraton Hotel Albuquerque Airport
We should mention
This property offers transfers from the airport and train station. Guests must contact the property with arrival details on arrival, using the contact information on the booking confirmation. The property allows pets in specific rooms only and has other pet restrictions (surcharges apply and can be found in the Fees section). Guests can arrange to bring pets by contacting the property directly, using the contact information on the booking confirmation.


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Chocolate Angel Food Cake Recipe
3.5 3
I love to bake but I need to watch my diet so I came up with delicious cake that I don't feel guilty about at all.—Margaret Zickert, Deerfield, Wisconsin
- 1 cup cake flour
- 1/2 cup baking cocoa
- 2 cups egg whites (about 14)
- 2 teaspoons cream of tartar
- 2 cups sugar
- 1 teaspoon vanilla extract
- Sift flour and cocoa together three times; set aside.
- In a large bowl, beat the egg whites until foamy. Sprinkle with cream of tartar and beat until soft peaks form. Gradually add sugar, about 2 tablespoons at a time, beating until stiff peaks form. Blend in vanilla. Sift about a fourth of the flour mixture by fourths. Pour into an ungreased 10-in. tube pan.
- Bake at 325° for 1 hour. Turn off the oven, but let cake sit in the oven for 5 minutes. Removed from the oven and immediately invert pan; cool. Loosen sides of cake from pan and remove. Yield: 12 servings.
Originally published as Chocolate Angel Food Cake in Country Woman July/August 1995, p36
Reviews for Chocolate Angel Food Cake
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See our store section for gifts by different stores
See our top gift ideas section for most popular items.
Create your own personal gift registry. Register for any item, from any store, for any occasion. Find the gift registries of your family and friends.
Ever find the perfect gift idea for someone, but their birthday was months away? We make it easy to remember your gift ideas.
Provides timely email reminders for a birthday, anniversary, and other special occasions.
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Personalized Christmas Lights T-Shirt Teddy Bear
Happy Mother's Day Teddy Bear


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Cameras, Photos & Video
Televisions, Video & Home Theater
Portable Devices
Mobile, Tablets & Smart Devices
Home Audio
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Model # MDR-Q23LPPS | change model...
This model is also known as: MDRQ23LPPS, MDRQ23LPPSBLK, MDRQ23LPPSWHI,
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Links please wallpaper uzip good job man
Amazing ! Ö
good!can you share LS??
nice!but I Can't have.
Wow! I love it
grats on the DD mate, well deserved
wow, awesome <3
Pretty amazing and a brilliant thought for mobile interface!
Wow! This series of pictures are really amazing!
Sadly, today, everything is now digital!
Very nice, I would love this for my android Anybody knows where could I download it?
PS: Congrats on the DD
PS: Congrats on the DD
Nice set up! Looks Apple-ish. Congrats on the DD~!
looks good and is kinda similar to apple. :3
it's nothing like Apple at all
super cute! totally wish my phone was compatible D:
so cool
This. Is. AWESOME.
It's for android people! It's probably MIUI! This is amazing though. The customization of MIUI is incredible.
someone needs to put this on cydia!
like the Caculator... Is that a mistake by purpose?
What mistake?
It says 2 + 1 + 5
It says 2 + 1 + 5
so clever!!
Awesome ...
omfggg please <3 <3
great for iphone AND ipod
great for iphone AND ipod
Download soon?
Very nice interface, would be great for an iPhone
Sweet, really well polished.
omg is this for the Android competition mate ?


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Posts tagged with My plug-ins
Cropping with Syncomatic
Syncomatic is my plugin that syncs metadata and adjustments between files with similar names or within stacks. But one thing has annoyed me ever since I wrote it 6-7 years ago – it couldn't sync the crop.
I always wanted to do it – why wouldn't I? – but for reasons best known to themselves Adobe didn't make crop available and . . .
Syncomatic and LrMobile
I've updated Syncomatic to facilitate an interesting new workflow involving LrMobile. Shoot Raw+JPEG in the field, import the JPEGs and adjust them in LrMobile, and then sync that work to the raw files with Syncomatic.
Caption builder added to Search and Replace plugin
Anyone want to try a new feature that's coming in my Search and Replace plugin? The new feature is called "caption builder" and lets you build up captions from other fields.
Search & Replace 1.45
I've just released version 1.45 of my Search and Replace plug-in. This version is a significant upgrade. As well as including new Lr5 fields and features enabled in Lr5, I've really updated the layout and added some handy new capabilities to the existing features for searching for and replacing text in your metadata.
List View 1.66
I've just released version 1.66 of my ListView plug-in which displays images in a list style just like in most other DAM programs and lets you export metadata to Excel or other apps.
Changing the case of text
I've just uploaded version 1.41 of my Search and Replace plug-in.
It has a bit of tidying up, more language support, and also adds a button to change the case of text. Each time you click the button, it cycles on to a different case. So if you type some captions in capitals, it can convert them to lower case, capitalize . . .
Syncomatic 1.44
I've just released version 1.44 of my Syncomatic plug-in which synchronizes the metadata of files with matching names.
The change is a "Merge Keywords" checkbox which replaces one called "total keyword sync" which sneaked into 1.43 but didn't do anything except provoke a few puzzled emails. "Merge Keywords" works, and I hope it's a more intuitive name for the feature.
So what does . . .
List View 1.59
I've just released ListView 1.59 with a series of significant changes and improvements
List View plugin updated
I've now released version 1.57 of my List View plug-in. The main changes are:
Thumbnails are now displayed in Lightroom 4
Export to CSV format – better for anyone who uses the Numbers spreadsheet or for data exchange with databases
Close to Sorted Collection button. One thing people like about the plug-in is sorting by almost any field, so this button saves the . . .
Locktastic 1.25
I've just released a revision to my little Locktastic plug-in which is designed to help photographers who "lock" certain pictures in the camera. Some do this to identify pictures they particularly want to work on when they get back to their desks.
As a result of a user request, the plug-in now bypasses Lightroom's Import dialog and imports only those images. . . .
Search and Replace plug-in – version 1.35 coming
If you use my Search and Replace Lightroom plug-in, I'm currently updating it. So if there's something you want, now's a good time to ask.
List View – new Lightroom plug-in
It's been bubbling away for a while, and some people saw it late last year, but in the next few days I'll be releasing a new plug-in – List View.
It does exactly what the name suggests and provides a list view which some of us feel is sorely missed in Lightroom's Library. After all, it's a lot easier to review . . .
A perfect shot – in the foot?
No matter how much the Lightroom ethos is about designing a program for photographers from the ground up, there are still those atavistic folk who want to do things just as they suppose they've always done them. So every so often you'll get people wanting Undo to be Alt-Ctrl-Z because it's how Photoshop has always worked, forgetting that the vast . . .
Complex file renaming in Lightroom made simple – thanks to the Search and Replace plug-in
Ever spend ages thinking up ways to convince someone a task is far from easy, and that they should just give up on the idea – and then the solution appears just as you were about to hit the Send button?
Well, the other night I had an interesting email from someone who has my Search and Replace plug-in for Lightroom:
… . . .
Search Replace Transfer 1.30
Search Replace Transfer 1.30 fixes a bug, which 1.29 kindly introduced, but it also contains a new menu command – "Brute force" search which creates a regular or "dumb" collection and then adds images to it by performing a "brute force" search through the selected items or through the entire catalogue.
The intention is to fill . . .
Lightroom – finding all images shot at a certain time of the year
Recently I've seen a number of Lightroom users asking how they could find all images shot at a certain time of the year.
Now, if you have your head screwed on you would have included seasons in your keywords. For instance, an image of snow might include "winter" in the keywords (unless you live at the North or South Poles) while . . .
Capture Time to Exif – released
Capture Time to Exif is essentially an in-Lightroom interface for Exiftool, Phil Harvey's highly-respected "platform-independent Perl library plus command-line application for reading, writing and editing meta information in a wide variety of files".
With Capture Time to Exif you can:
Update the Date Time Original EXIF field of scanned images. Lightroom's filter panel and smart collections can then . . .
SiteMaker as a single gallery
Here's another preview of my SiteMaker web gallery showing its huge flexibility.
May I, as the saying goes, draw your attention to:
Here it's a single "contact sheet" gallery. SiteMaker can be either for a complete photo site or for a proofs gallery of a single set of images – or both
All the thumbnails and their descriptions are shown in this case, . . .
New Lightroom plug-in – CaptureTime to Exif
CaptureTime to Exif is my latest Lightroom 3 plug-in. Essentially it's an in-Lightroom interface for Exiftool:
Initially it was for Lightroom users whose catalogue contains scanned images and who wanted to make the scans' Date Time Original EXIF field correspond to when the pictures were originally taken rather than when they were scanned. But people said they wanted to add the . . .
SiteMaker for Lightroom
SiteMaker is the name of a new and very-soon-to-be-unleashed web gallery for Lightroom 3 which aims to create a complete web site within Lightroom.
The front page is designed so you can highlight three key groups of images – for example "Latest work", "Landscape portfolio", "Black and white portraits". So the top part of the site has three full width images . . .


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/ Local
WALSALL leather will be the subject at Dudley Local History Society's first meeting of 2013.
The group will meet on Thursday January 17 at 7.30pm at the United Reformed Church in Trinity Road where members will welcome Francesca Cox, who will be speaking about the history of Walsall leather and her work at the Leather Museum.
Entrance is £2 and non-members are welcome.
Promoted Stories
Comments are closed on this article.


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438 Views 3 Replies Latest reply: May 15, 2011 1:52 PM by babowa
babowa May 14, 2011 11:54 PM
in response to w-r
It is not a virus. It is a trojan. You might want to read this:
k13090k May 15, 2011 1:42 PM
in response to babowa
Sorry, I'm not a technofile. I just wanted to get rid of something I thought may screw up my computer. I didn't use the correct words, I'm sorry. I did not infuriate anyone. I will not be using this site again unless I consider it a real emergency.
Thank you for your response.
babowa May 15, 2011 1:52 PM
in response to k13090k
I'm sorry that my telling the OP - who does not seem to be you unless you are posting from two accounts - that s/he does not have a virus and that they would benefit from reading the very informative website of one of our own who has spent a lot of his time researching this trojan, seems to have upset you.


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Sunday, November 1, 2015
Our Closing Auction and a Glimpse of the Future
A huge thank you goes out to everyone who attended our last pop-up shop and liquidation sale on Oct. 25th! We had a great day and covered all of our overhead for the last month of being open. Yesterday - October 31st - was our last day of classes and we were lucky enough to have some great students in our final Machine Intro who are now charged with taking up the sewing torch and running with it. And another thank you to Ripley, who took time out of her busy schedule fighting aliens to come teach class.
On Saturday November 7th, 2015 we will hold a public auction at Sew L.A. to sell off all of our machines, tools, furniture, fixtures and miscellany. I'd love for the people who are interested in something specific to get a good shot at it without waiting around all day, so below I have a schedule for the day of what will be sold and when. There is A LOT of stuff and I'll be wielding the hammer myself, if I don't lose my voice by the end of the day! Here's the deal:
11am - 1pm:
Remainder of stock, misc. supplies, random made stuff, class and workshop items. This includes our Kids Camp bin with all the patterns, leather tooling stuff, classroom looms, leftover Machine Intro bag fabric, a box of leather bracelets, the framed fabric in the bathroom and a bunch of stuff made by me that I don't have room for.
2pm - 4pm:
Machines and Tools - five Viking Scandinavia 100s, one Viking Classica 105, seven Janome MS5027PRs with walking feet, four Janome MyLock 634Ds, three Rowenta irons, 4 ironing boards, all the pressing equipment, classroom tools including Gingher shears and magnetic pincushions.
5pm - 7pm:
Furniture and Fixtures: sewing related and shop related. Pattern cabinet, giant thread cabinet, custom built wooden cutting tables (two ginormous and one human size), a lot of sturdy IKEA stuff like 8 cube and 4 cube Ektorp shelves with wheels, 3 Billy bookcases modified to fit fabric bolts, lots and lots of chairs. Shop stuff includes two Billy bookcases with glass doors, two giant white slat wall pieces with hooks, various display stuff, display mannequins, a stand whiteboard, a couch with two washable turquoise covers, a million button tubes, microwave / fridge, a register stand, an industrial dolly and a lot more.
And at 7pm, I'd love to have a glass of champagne with anyone who wants to show up!
Once again, that's Saturday November 7th, from 11 - 7pm at 3153 Glendale Blvd. 90039. We'll accept cash and cards!
Please don't email or call in advance of the auction to have us hold items (certainly do if you have questions) as we all feel this is the most fair way to get stuff to people. And although we expect there will be tons of great deals, to be honest we need all the money we can get from this to pay all the debt accumulated over the past 9 years.
After the auction, I'll be taking a few weeks to settle into my new routine, and we'll be re-launching the website by the end of November with Sew L.A. patterns (retail and wholesale) and kits and some fun and useful items for your sewing pleasure. We'll be carrying notions required by our patterns (cotton strapping, bodkins etc.) and also some great hard-to-find basics. I have three new patterns in the works (a skirt and two dresses!) and have been more than inspired by my computer drafting class to start in on a bunch more. And I'm excited to see what the next few months and the new year will bring! I love new beginnings...
Posted by Shaerie Mead 3 comments:
Labels: end of an era, store update
Friday, September 4, 2015
CreativeLive Classes Are Here!
If you follow Sew L.A. on Instagram, you will have seen some behind-the-scenes pictures of me filming some classes for CreativeLive - and here they are! I'm really thrilled to present them - they were a TON of work and a lot of fun, and I got to collaborate with some incredible people. I can't wait to film more!
Box Zip Bags has been one of our most popular classes since the pattern was released this past March. Now, you can follow along step by step whenever you like!
Our Easiest Skirt is a beginner staple - learn how to read a pattern and size yourself, and get all the info needed to start sewing garments. Even though I have been sewing for most of my life, this is the skirt I make the most! It's the perfect canvas for amazing fabric.
A little bit more involved - but still beginner friendly - it's the pretty, practical pockets that make our Vintage Pocket Skirt such a huge hit! This skirt has a flat waistband in the front for a more fitted look, but there's elastic in the back for comfort. You'll learn the basics and a bit more!
If any of you existing Sew L.A. peeps decide to take one of these classes, please let me know what you think! I love teaching in person, but for people not in LA and people who want to learn from me after Sew L.A. closes, this is the solution. And since September is National Sewing Month, CreativeLive is offering these classes at 30% off for the whole month! Woo hoo!
Posted by Shaerie Mead No comments:
Labels: classes, CreativeLive, Sew L.A. Patterns
Tuesday, August 18, 2015
Thank You for 8 Awesome Years!
This is the post that no business owner ever wants to write. After a year-long struggle to keep Sew L.A. going, I have decided to close the classroom & shop at the end of October 2015. Our classes are scheduled through October 31, and all of our teachers are staying to see this through. We are all hoping to go out with a bang and a party!
Before getting into the details, let's talk gift certificates. We have taken them off the site so they are no longer available, but if you have one please use it before the end of October. If you have one and don't plan to use it, consider donating it back to the shop (so we can track it) - this will help keep our sales up so we can exit gracefully. Reducing our liability will be a great way to do this, and you can also help by attending our Very Loud Auction after our last classes.
At our teacher meeting this past Sunday, I went over some of the key reasons for closing, both business related and personal. On the business side, our market has definitely changed and we found that out a little too late to maneuver the shift effectively. When Sew L.A. started, we were the only classroom on this side of the city that offered quality classes, and this synced up with the market willing to pay for information from professionals. Now, anything you want to search for is available on the internet (regardless of quality) and there are several online learning websites that offer a high quality experience for a fraction of what we charge for in-person classes. I started Sew L.A. in 2007 for a few reasons - one being I believe that in-person is the best way to learn, but I cannot deny that online reaches a huge audience and AS ALWAYS the market follows the demand.
There are a few other reasons I started Sew L.A. - I had been making corsets in my studio for years, and was looking for more of a community instead of working solo every day. I had discovered a love for teaching that needed to be shared. And ultimately, I was looking for work that would allow me to someday afford a family. When I was pregnant for Lux in 2012, all of that seemed possible - the shop was doing well and we were able to cover the costs of moving to our current location, along with stocking it and staffing it.
We had great years in 2012 and 2013. I had a rough time finding care for Lux that we could afford until he was 11 months old - he was my first, and I had NO IDEA what a problem quality care would turn out to be (I'll save the Saga of the Wait Lists for another time). The shift in the market started at the end of 2013 for us, when I had one day a week of care for Lux and actually needed to be back at the shop full time. The cost of replacing myself had just gone up and no one realized it at the time.
We had to close our retail shop this past April because a fabric inventory is one of the most difficult to support in retail. Our venders know this, and even give us 60 days to pay invoices because the majority of the stock moves SO SLOWLY. I had a large sum of money tied up in the shop that was needed to pay teachers. Our classes have always done well, and our retail shop has never quite paid for itself - so the decision seemed perfect. In reality, the loss of visibility and the lack of funds for re-working the website just hastened the decision to close altogether.
The current truth is that I personally cannot devote the attention to Sew L.A. that I once could because I have a wonderful 2 1/2 year old that I'm taking care of. My passion is teaching, and because of the daycare available to me and my husband's schedule I cannot teach evenings and weekends - which is when we have our classes. Therefore, I'm still paying people to replace me in my business even now when I have four days a week to be here and working.
This leads directly to what running Sew L.A. has cost me personally. I take great pride in being a person who does what they say they will do, and I certainly don't use the word 'humbled' lightly - these past two years have humbled me on several levels. Learning that sometimes I cannot fix it, no matter how hard I work - learning that sometimes the appearance of expertise is more valued than actual expertise - not being able to honor financial commitments - juggling creditors - feeling envy and jealousy instead of happiness at the success of others - the list goes on. I was becoming a person I did not want to be.
Sew L.A. was started with a loan from the VEDC, and I took out and paid off three other loans during the course of our existence, but since I had no other source of income, much of the shop's expenses were put on two business credit cards and this is what I'll be carrying with me after closing (not a small amount). I could file for bankruptcy, but in that event my wonderful staff and amazing landlord (my actual priorities) would be pretty low on the list. So even after the doors close and everyone has been paid I'll still be in debt, with a toddler, with no degree and outdated bookkeeping skills. Unfortunately, this is a very common situation for people who close businesses to be in - I am far from alone. That doesn't make it any easier, and it doesn't make it right. I haven't paid myself in two years, and now I need to take care of my family.
I once made the mistake of telling a friend, while childless, that owning a small business was just like having a kid (I have since apologized profusely). But I can say for sure that it is like having a kid in that no one can tell you what it's like beforehand, and no on who hasn't gone through it can really comment on the perks and difficulties. And even then the experience is different for everyone!
I prefer to end on a high note and think about all the lives we have touched, all the people and kids we have inspired, and all the fantastic sewing there is in the world because of our classes. It has been my privilege to work with AMAZING, TALENTED and CREATIVE people over the past 8 years, and if you'd like to continue working with these people after October here is some contact info:
Rebecca Prange, Teacher: firstname.lastname@example.com
Christine Haynes, Teacher: http://www.christinehaynes.com - firstname.lastname@example.com
Heather Quesada, Teacher: http://www.heatherquesada.com - email@example.com
For my own self, I will continue to promote quality learning however I can. I'm all for mad creativity and winging it, but I really do feel that having a solid base of skills can only help you be madly creative and wing it. That's how we have operated for our whole run, and I don't intend to stop now. One student recently asked in one of Rebecca's lessons "How come I learn SO much in my classes here?" and the answer is we know that learning well takes time and we have always tried to give you that time in classes and lessons to absorb the 'why' as well as the 'how'. Which is actually rare in this world that gives results more weight than process.
I will be continuing the Sew L.A. website with our patterns and kits and this here blog, and even though I'll miss all my peeps and the pretty fabric (oh, the fabric…) I am trying to be ready for the Next Thing.
Posted by Shaerie Mead 25 comments:
Labels: ch ch changes, end of an era
Thursday, June 11, 2015
Make Your Summer Crafty!
Summer classes are in full swing here at Sew L.A., and we couldn't be happier with our reorganized classroom space! It's the perfect size for our sewing classes that take a bit more room for projects, and we have had a few creative workshops with 10 - 15 students as well.
Our website update is taking a bit longer than we anticipated, but we have our Basic Sewing Kit up and are getting ready to post fabric soon. A huge thank you to students who have been in the middle of this change! Of course, we want everyone to have the right tools and supplies for classes and workshops - if you don't see what you need online yet we are ALWAYS open 1/2 hour before classes to allow students to shop for what they need. Please do send us an email if you ever have questions!
You can also plan ahead and get what you need (and anything else) at one of our monthly pop-up shops: the next one will be Saturday June 20th from 10 - 6pm. We have some new fabric from Cloud9 and Cotton + Steel!
There are some great sewing classes coming up in June and July, along with more crafty classes like Embroidery and Sashiko Mending - and here are some pictures from our recent Block Printing workshop, led by Elinor from Krank Press:
|photo by Elinor
|Decades of Style E.S.P. Dress in ah-MAY-zing Alexander Henry fabric
|Look for the Aster Blouse class in August!
|Working hard on a new beginner class & pattern!
And there are a few more super-secret projects in the works - you'll have to stay tuned till next time! Hope to see you soon -Shaerie @ Sew L.A.
Posted by Shaerie Mead No comments:
Labels: Alexander Henry, classes, fabric, project, store update
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Friday Afternoon Musicale
Welker Room, James Laughlin Music Center
Fee: Free Admission
Four Hands Piano Recital, with Christine Kefferstan and Yeeha Chiu. Featuring the music of Bach, Schubert, Dvorak and Debussy, come start the year off with the first of our monthly series.
Registration and Directions
Registration has closed. Please contact Emily Paxman at firstname.lastname@example.com for additional information.
Fee : Free Admission
Location : Welker Room, James Laughlin Music Center
Event Contact InformationEmily Paxman and Pauline Rovkah


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3-10 years
Let the JCC fill your child's afternoon with friendship, fun and even some homework help! Kid's Place offers after-school games and activities, both indoor and outdoor, and a snack. Our warm, nurturing staff will provide children with a safe and loving after-school environment.
Kid's Place is open Monday through Friday, 3:00-6:00pm. If your child takes an after-school class at the JCC and you'd like to take advantage of Kid's Place before and/or after class, we'll be happy to escort your child to and/or from the class.
Kid's Place will begin on Thursday, September 17, 2015 and will be closed on all JCC Nursery School holidays.
Kid's Place may be paid for on a daily basis, parents may pay in advance for blocks of time, or parents may pay a monthly fee. For information. call (914) 472-3300, x316
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Jennifer Love Hewitt's Short Breakup Hair: Love It Or Leave It? (PHOTOS)
Jennifer Love Hewitt split from her boyfriend Jamie Kennedy a couple weeks ago, and now she has shed something else--her long locks. No word on whether Jennifer has changed her vagazzling habits. Is she making a good fresh start?


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Hi I've checked my site at your validator and it's found many "errors" like - required attribute "ALT" not specified - and other boring things like that. Do you seriously think that it is important to find errors which are not really errors? YuriReceived on Thursday, 7 February 2013 08:04:00 UTC
This archive was generated by hypermail 2.3.1 : Friday, 27 November 2015 11:01:39 UTC


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Get lost in our MoOM, The Museum of Online Museums.
Fresh Signals
High up on a mountain in Colorado, a day spent at Glenwood Caverns Adventure Park, a place where I would have zero fun and multiple panic attacks. -sd.08.26.14 #
A post from the daily flow of linkage called Fresh Signals, at Coudal.com.


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About Bobbyweather
Hi. I am Bobby Yoo. As of Oct. 2014, I am seventeen, live in Seoul, S. Korea, and like meteorology, especially those related to tropical cyclones.
By: Bobbyweather , 7:36 AM GMT on November 19, 2008
For the 2008 Northern Hemisphere TC season archive, see here.
As of 1800 UTC, Moderate Tropical Storm Fanele has maximum sustained winds of 35 kt and minimum pressure of 994 mb. Here is the latest advisory summarized:
RSMC La Reunion
Warning number 19 for Moderate Tropical Storm 7 (Fanele)
Jan 22 2009 1800 UTC
The center of Ex-Fanele is located within 30 nm radius of point 26.4S/51.6E and is moving southeast at 15 kt.
Dvorak analysis is T2.5/2.5, the central pressure is 994 hPa, and the maximum average wind speed (10-min sustained) is 35 kt. The radius of maximum winds extend out to 50 km. The first closed isobar is 1006 hPa and the average diameter is 500 km.
Extension of winds by quadrant:
12 hr: 28.8S/52.6E, max wind 35 kt, Extratropical
Additional information:
Since the system has moved back over water, Fanele has a well-defined LLCC but quide wide where no deep convection has managed to build today due to moderate northwesterly wind shear. Quickscat pass at 1453Z show a wide central area of relatively weak winds (diameter about 40 nm) surrounded by a crown of strong winds. Extratropical transition is underway as system is currently leaving the heat content waters.
Most of the available NWP models are in good agreement with the forecast track.
___________________________________________________________Next, there is Tropical Depression 06F. It has not changed much. The chance for it strengthening into a TC is low.
List of 2008-09 Southern Hemisphere storms
South-West Indian Ocean
01R.NONAME- Area of Disturbed Weather
02R.Asma- Moderate Tropical Storm
03R.Bernard- Moderate Tropical Storm
04R.Cinda- Severe Tropical Storm
05R.Dongo- Severe Tropical Storm
06R.Eric- Moderate Tropical Storm
07R.Fanele- Intense Tropical Cyclone
Australian Region
(I will change HGW's I into S.)
01S.Bernard- Tropical Low
02S.Anika- Category 2 TC
03S.Billy- Category 4 TC
04S.NONAME- Tropical Low
05S.NONAME- Tropical Low
06S.Charlotte- Category 1 TC
South Pacific Ocean
01F.NONAME- Tropical Disturbance
02F.NONAME- Tropical Depression
03F.NONAME- Tropical Disturbance
04F.NONAME- Tropical Depression
05F.NONAME- Tropical Depression
06F.NONAME- Tropical Depression
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Hi. I am Bobby Yoo. As of Oct. 2014, I am seventeen, live in Seoul, S. Korea, and like meteorology, especially those related to tropical cyclones.


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Adjunct Professor of Epidemiology
Other Affiliations
Professor of Public Health and Epidemiology and Director of the Institute of Public Health at the Charité – Universitätsmedizin Berlin, Germany.
Adjunct Associate Epidemiologist, Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
My principal areas of research consist of three main focuses:
- the interrelationship between vascular risk factors, neurological diseases, and cardiovascular disease with particular focus on migraine, stroke, restless legs syndrome, and Parkinson's disease [neuroepidemiology/cardiovascular epidemiology];
- the evaluation of risks and benefits of medication use [pharmacoepidemiology]
- the evaluation of methods to control for confounding, particularly the propensity score [epidemiologic methods].
M.D., 1996, Eberhard-Karls-University, Tübingen, Germany
M.Sc. (Epidemiology), 2000, Harvard School of Public Health
Sc.D. (Epidemiology), 2003, Harvard School of Public Health
Useful links


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PQRS: Are You Ready?
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STARmeterSEE RANK
Up 132 this week
Kate Murtagh (I)
Kate Murtagh was born on October 29, 1920 in Los Angeles, California, USA. She is an actress, known for Farewell, My Lovely (1975), The Car (1977) and The Night Strangler (1973). See full bio »
Born:in Los Angeles, California, USA
More at IMDbPro » Represent Kate Murtagh? Add or change photos


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5d and sigma 150mm macro
Started Feb 21, 2006 | Discussions thread
Shop cameras & lenses ▾
Regular Member • Posts: 123
5d and sigma 150mm macro
Feb 21, 2006
Can anyone with the 5d and new sigma 150mm macro (or any ff camera) say how the lenses performance is? Here's a link to a really great site comparing several macros, but it was done a while ago so the 150 isn't included.
The site's in german (there's a translated site somewhere), but the pics are good and can be enlarged. The 50mm sigma looks incredible but the 105 is pretty awful. I'm wondering how the 150 would compare.
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Hp 940xl C4906an
December 6, 2015 by Orlando Florida Magazine
Filed under In the News
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From Wikipedia, the free encyclopedia
|Look up servitude in Wiktionary, the free dictionary.
Servitude may refer to:
- Conscription
- Equitable servitude, a term of real estate law
- Indentured servitude
- Involuntary servitude
- Penal servitude
- Service
- Servitude (BDSM)
- Servitude in civil law
- Slavery
|This disambiguation page lists articles associated with the title Servitude.
If an internal link led you here, you may wish to change the link to point directly to the intended article.


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Another part of the Democrats' magic work is to convince the American people that Bush places a higher priority on the ouster of Saddam Hussein than going after al Qaeda. That's believable if you can be made to believe that our armed forces attacked Iraq before they attacked Afghanistan. But suppose Bush had "done something" like taking military action against al Qaeda and the Taliban in Afghanistan prior to Sept. 11. I'm betting there would have been the same howls of protest from the United Nations, France and Germany and the Democrats that there were prior to the Iraq invasion.
Fighting terrorism as well as rogue dictators requires a policy of pre-emption. During the 1930s, there should have been a pre-emptive strike on Nazi Germany. Had Britain and France had the guts to do that, 60 million lives lost in World War II might have been spared. After World War II, when we held a monopoly on nuclear weapons, we should have told the U.S.S.R. that if it started making nuclear weapons we'd bomb its facilities. We would have avoided Soviet adventurism and trillions of dollars fighting a cold war. Today, we should give axis-of-evil member North Korea notice to destroy its nuclear weapons or we'll do it for them.
You might ask, "Williams, are you a warmonger?" No, I'm not, but here's the way I look at it. If you hate my guts and have designs to hurt me, and I see you building a cannon aimed at my house, I am not going to wait for you to finish construction.
Rush Limbaugh defends Rubio's debate answer: He's absolutely right that Obama knows what he's doing | Allahpundit
Time for Team Hillary to break out the gender card for young liberal women who prefer Sanders | Allahpundit


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This article is a joint publication of TheNation.com and Foreign Policy In Focus.
This week, the House will vote on the Electrify Africa Act. This bill directs the president to draw up a multi-year strategy to strengthen the ability of countries in sub-Saharan Africa to "develop an appropriate mix of power solutions" to provide electricity, fight poverty and "drive economic growth."
Because of strong pressure from climate justice advocates, some positives—such as integrated resource planning and decentralized renewable energy—are named as a part of that mix. But because it still leaves the door wide open to fossil fuels, the bill doesn't go far enough to protect people or their environment.
And the debate over Electrify Africa continues as the Senate drafts a companion bill.
Powering Fossil Fuels
Behind both pieces of legislation is a White House initiative announced last summer called "Power Africa." It frames President Barack Obama's approach to energy investment on the continent, which has been condemned by environmental justice groups. It's an "all of the above" energy strategy that favors the fossil fuel companies that are destroying the planet and corrupting Washington.
Proponents of Electrify and Power Africa have been most publicly enthusiastic about new discoveries of vast reserves of oil and gas on the continent, which has many African activists wary of a resource grab. Executives from companies like General Electric—which according to Forbes has recently pivoted its attention to the continent—have appeared on the podium with President Obama to applaud the policy.
At a March Senate hearing on Power Africa, Del Renigar, senior counsel for global government affairs and policy at GE, even noted that one of the company's "most significant efforts to date has been focused on the privatization of the Nigerian power sector." He lauded the potential of Power Africa to help "reduce the obstacles" to negotiating deals for power projects. And some backers of dirty energy are attempting to use the initiative to weaken the existing environmental safeguard policies of national development finance institutions such as the Overseas Private Investment Corporation (OPIC).
The backers of keeping dirty energy in Power Africa like to portray their opponents as privileged elites who want to keep Africans "in the dark" by denying them electricity and industrialization, while keeping their own lights on.
Nothing could be further from the truth. The real concern here is that US taxpayers will wind up supporting African energy development that caters to corporate industrial zones and natural resource exporters, leaving the majority of Africans in rural and neglected urban areas still without access to power and exposed to dangerous pollution.


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Sughran's Group
Sughran is a housewife and does her houswork. She is very active and performs her duties very well. She cooks food for the family and keeps her home clean.
She has applied for a loan from Kiva partner Asasah for her son who operates an eggs sales business. Eggs sales increase in the winter season because this is an good food item that stays fresh in the cold.
With this loan, he will buy eggs in bulk quantity and will supply them to different grocery shops in the market to earn profits.
He is relatively new to his business and working very hard. Sughran is hopeful that an investment will help him get established in the business.
Note: "In the photo, the lady holding a book (called Asasah Passbook) is Sughran".
Additional Information
This is a Group Loan
In a group loan, each member of the group receives an individual loan but is part of a larger group of individuals. The group is there to provide support to the members and to provide a system of peer pressure, but groups may or may not be formally bound by a group guarantee. In cases where there is a group guarantee, members of the group are responsible for paying back the loans of their fellow group members in the case of delinquency or default.
Kiva's Field Partners typically feature one borrower from a group. The loan description, sector, and other attributes for a group loan profile are determined by the featured borrower's loan. The other members of the group are not required to use their loans for the same purpose.
About Pakistan
345View loans »
Success!! The loan was 100% repaid
- Repayment Term
- 13 months (Additional Information)
- Repayment Schedule
- Monthly
- Pre-Disbursed:
- Dec 26, 2011
- Listed
- Jan 1, 2012
- Currency Exchange Loss:
- Possible
- Ended:
- Dec 15, 2012


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DandDCustoms GI JOE COBRA VIPER 6.5 to 7 inch fully poseable Marvel Legends Style action figure. Custom sculpting and painting. We wanted to make this cobra viper look like the arise serpentor movie version and original series figure but in a 6 inch scale body. We added some pics that show the detailed cobra insignias. We actually added insignias for each side of his arm as we thought it would look cooler. We could have just sculpted the helmet to be permanent and look identical to the viper's helmet, but we decided that it would be better to have a helmet that you can take on and off. The visor can come off so that you can see his face while his helmet is on and the helmet also comes off entirely so you can just have his head by itself. We try to make every head different to have a unique army of vipers. This one is actually lucius malfoy. I would have never thought he was a cobra but you know those talented actors have a wide range.
We have all together about 35 or more gi joe cobra marvel legends style customs with multiple variations of them. Please browse our other customs to see prior gi joes. We try to put up one a day on this site This is our version 1.0
|Punisher Vs Jigsaw
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|Cobra Crimson Guard Marvel Legends Style
|G.I. Joe Series
|Cobra Viper Marvel Legends Style
|Cobra Crimson Guard Marvel Legends Style
|Created by D&DCUSTOMS
|Cobra Viper Marvel Legends Style


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Lent arrives on February 10! Sign up today for a Lent devotional experience.
The contrast between Abraham's two sons is established in terms of their social status (v. 22) and the manner of their birth (v. 23). Ishmael's mother, Hagar, was Abraham's slave; Isaac's mother, Sarah, was Abraham's wife, a free woman. Since the social status of the mothers determined the social status of their sons, Ishmael was a slave and Isaac was free. Furthermore, there was nothing supernatural about Ishmael's birth: it happened in the ordinary way, as a natural result of the sexual union of Abraham and Hagar. NIV's in the ordinary way is a good paraphrase of "according to the flesh." In this context flesh is not used as a negative, judgmental term; it simply indicates that Ishmael's birth was not caused by anything except the normal biological processes of conception and birth. On the other hand, Isaac was born as the result of a promise. The only way that Abraham's sexual union with his aged, barren wife Sarah could have resulted in conception and birth was by the supernatural fulfillment of the promise of God.
So far Paul has simply summarized the biblical narrative of Abraham's two sons. But what a dramatic contrast his simple summary sets forth: slavery by natural birth and freedom by supernatural birth! It does not take much imagination to see how this contrast could be effectively used to illustrate and apply the truth already given in this letter. If you have only experienced natural birth, you are by nature a slave. But if you have experienced supernatural birth by the fulfillment of God's promise in your life, you are by God's grace set free. Before Paul develops these personal implications, however, he sets up a series of allegorical comparisons.


text: ECKLIPZE Ecklipze los Angeles/Chicago Collaborate or Inquiries: firstname.lastname@example.com BOOKING: firstname.lastname@example.com ☆☆ ECKLIPZE ☆☆ Trenchant Records - Black Market Noise (BMI) - Dog Bites Wolf (ASCAP) - Track Star Productions Kyle English, P.K.A. Ecklipze, is a music producer and DJ from Vernon, BC. Ecklipze was signed to Chicago record label, Trenchant Dubs, in mid-2012 and has quickly become the labels' flagship artist. As a musician and composer, Ecklipze creates electronic dance music in a variety of styles including dubstep, trap, bigroom, and bass music. A typical Ecklipze set includes an upfront selection along with many of his own original tracks, bootlegs, and remixes. ECKLIPZE is currently in the studio finishing up a new EP titled "Diamond In The Rough" which features HLTR$KLTR, a Trap producer from Miami. Ecklipze has also been recruited by his publisher, Black Market Noise (BMI), to become the producer and full-time member of a recently formed band called Neon Black. The band will feature members of American alternative rock band, Madina Lake. Neon Black is currently in the studio finishing the recording of their debut EP. Ecklipze's first single was released in October, 2012. "Breathe" and "Bullet" were equally impressive both sonically and in their composition. "Breathe" received great exposure after being used as the soundtrack to an ad campaign for Forever 21 clothing, which was followed by two prominent placements on Season 10 of the hit television dance competition, "So You Think You Can Dance". Most recently "Breathe" Has also been placed on the Pilot Episode of "Chasing Life" Premiering on ABC this June & an ad campaign placement with FOX Clothing Company. "Breathe" & "Bullet" along with the track "Blackout" from "The Purge EP" were also included on a variety of Dubstep and Bass Music compilation cd's along side artists FIGURE, Far Too Loud, Pegboard Nerds, Tut Tut Child, Louisiana Jones, RoughMath, Chrispy, Candyland, Klaypex, and KATFYR, all released via license to L.A based Record Label Hypnotic Records & Cleopatra Records. Ecklipze is currently playing events on The Spectrum Tour in support of his most recent release, "The Purge EP" which is out now & "Ultimate Terror" double Single which are available June 16th. Limited edition compact discs of The Purge EP will also be available at his forthcoming performances. ECKLIPZE's tracks GET REKT by ECKLIPZE published on 2016/02/07 00:06:03 +0000 Maroon 5 - Animals (ECKLIPZE REMIX) ///FREE DOWNLOAD\\\ by ECKLIPZE published on 2015/02/24 03:54:21 +0000 GOLD TOP - UH OH (ECKLIPZE REMIX) by ECKLIPZE published on 2014/10/17 22:13:24 +0000 COMMAND Q - BLOOD FROM THE STONE (ECKLIPZE REMIX) FREE DOWNLOAD by ECKLIPZE published on 2014/05/02 01:19:58 +0000 Madina Lake - Lila, The Divine Game (ECKLIPZE REMIX) FREE DOWNLOAD by ECKLIPZE published on 2014/01/18 23:37:24 +0000 Ellie Goulding - Hanging On (ECKLIPZE REMIX) FREE DOWNLOAD by ECKLIPZE published on 2013/09/19 04:22:11 +0000 Canadian Creatures by ECKLIPZE published on 2013/08/26 01:43:22 +0000 Certified by ECKLIPZE published on 2013/08/26 01:42:39 +0000 Blackout by ECKLIPZE published on 2013/08/26 01:42:07 +0000 Purge by ECKLIPZE published on 2013/08/26 01:33:36 +0000


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Kia Motors America (KMA) has teamed up with DC Entertainment and Super Street magazine to create a head-turning Optima Hybrid inspired by Superman's strength and unwavering care for planet Earth. Unveiled today at the 2013 Chicago Auto Show, this Optima Hybrid signals the continuation of a 10-month, eight vehicle partnership between Kia and DC Entertainment based on the iconic characters that make up the Justice League – Superman, Batman, Wonder Woman, Green Lantern, The Flash, Aquaman and Cyborg.
Tag Archives: project
SR Project VindicatorPosted in Ferrari
Over the years we have prided ourselves on being the first to show you all the amazing things the automotive world has to offer. Today, we are proud to present to you the world's first Ferrari FF with PUR wheels.
The inspiration for this FF comes from Project Era, as that car skyrocketed the popularity of the PUR 1NE design. From that moment on wards, it was clear that the 1NE design was meant for Ferrari's. With a set of twenty one inch PUR 1NE monoblocks mounted the FF was crowned with the name' Project Vindicator'.
Zagato TZ3, Texas Mile, Project Runningblade – 4/27/2010Posted in Alfa Romeo, Lamborghini
Zagato presents Alfa Romeo with a gift… the Zagato TZ3
Top Gear – Best Cars – Alfa Romeo 8CPosted in Alfa Romeo
BBC Top Gear Alfa Romeo 8C 0-60mph / 0-100kmh = 4,2 top speed = 182mph / 292kmh 450 bhp V8