text:
VIDEO: John McCain Admits Bernie Sanders Is Right About Income Inequality
Legal Scholar Michelle Alexander Explains Why Hillary Clinton Doesn't Deserve the Black Vote
What New Hampshire Actually Tells Us
Bernie Sanders and Donald Trump Prevail in New Hampshire Primary
VIDEO: Bill O'Reilly and Stephen Colbert Debate the Merits of Bernie Sanders and Donald Trump
Gary Indiana (Author), Louise Bourgeois (Artist) $64.23
By Mark Twain
Poster Boy NYC (CC-BY)
The public may never know whether justice is properly done unless someone leaks the details of this trial about leaks.
Julian Assange told "Democracy Now!" on Wednesday that the Pentagon and the Obama administration are going after "bright young men, determined, courageous and moral," like Jeremy Hammond, who pleaded guilty this week to hacking private intelligence firm Stratfor, the FBI and other institutions.
White House/Pete Souza
President Obama wisely avoided the phrase "mission accomplished" in his major speech last week about the "war on terror," but columnists aren't obliged to be so circumspect: It is time to declare victory and get on with our lives.
AP/Ivan Sekretarev
Not since the end of the Cold War in 1991 has Russia asserted itself so forcefully beyond its borders.
AP/Carolyn Kasterjavascript:void(0);
Sen. Angus King was the lone voice of sanity at a hearing where Pentagon officials said the war on terror could last up to 20 more years—or however long the president deems fit.
The U.S. Army (CC BY 2.0)
After an extensive examination of government spending data and contracts, I estimate that the Pentagon has dispersed around $385 billion to private companies for work done outside the U.S. since late 2001, mainly in the military baseworld.
Rape is center stage this week after the dramatic rescue of three women from close to a decade of imprisonment in a house on a quiet street in Cleveland.
Shutterstock illustration of American candle burning.
Among other effects, cancer clinics in March began turning away thousands of Medicare patients being treated with expensive chemotherapy drugs, which the clinics say they can no longer afford.
AP/Arlington County Police Department
Lt. Col. Jeffrey Krusinski, who heads the Air Force's Sexual Assault Prevention and Response unit, has been accused of the very thing he's been tasked with trying to stop.
Daniel McGowan, an Earth Liberation Front activist, was imprisoned last week for writing a HuffPo post; Fox News claims that Rutgers University firing its abusive basketball coach is evidence of cultural decline; and no, Bitcoin is apparently not the future of currency. These discoveries and more after the jump.
mrbill78636 (CC BY 2.0)
Almost half of the 2.2 million troops deployed in Iraq and Afghanistan report problems on returning home, but the attention and care many receive from the Department of Defense and Veterans Affairs are not enough, a report published Tuesday finds.
AP/Ric Francis
A majority of Americans now believe the Iraq War was a mistake, but memories fade. Most 18-29-year-olds say sending U.S. troops to Vietnam was not a mistake.
The Guardian has released a full-length documentary on the ties between "dirty wars" veteran and retired Col. James Steele, who played a crucial role in setting up and overseeing a network of detention and torture centers in Iraq that committed some of the worst acts of torture, and the top brass at the Pentagon.
U.S. Air Force/Staff Sgt. Jonathan Lovelady
If you Google "Afghanistan," you get your choice of occupiers.
AP/Biswaranjan Rout
A day will undoubtedly come when Osama bin Laden will occupy the same place in 21st century history books as Gavrilo Princip holds in the histories of the 20th century. Both committed acts that provoked great wars, brought down empires and profoundly altered their times.
By Mike Luckovich —
"If you look at the context of what he's done and the enormous damage he did to national security and our prestige around the world, throughout most of history someone like that would be executed," former Defense Department spokesman J.D. Gordon said of Pfc. Bradley Manning on Al-Jazeera this week.
I hate the sequester, beginning with its name. "Sequester" is a verb, not a noun. This ridiculous exercise is not just unwise and unproductive, but ungrammatical as well.
mindfrieze (CC BY-SA 2.0)
One good thing might come out of the sequester, according to comedian Andy Borowitz. In a satirical report for The New Yorker, he writes that the budget cuts may prevent American forces from fighting "totally optional wars based on bogus pretexts."
The U.S. Army Center (CC BY 2.0)
Parents who depend upon military-funded child care are among the victims of the $85 billion sequester cuts sweeping the country this week—$46 billion of which will affect Defense Department services that have nothing to do with war making.
DonkeyHotey (CC BY 2.0)
Since 2003, the Department of Homeland Security has grown into a miniature Pentagon. But unlike the Pentagon, it draws no attention whatsoever—even though this country has spent an amount of money equivalent to more than one and a half New Deals on "homeland security" since 9/11.
DOD/Cherie Cullen
The $400 billion boondoggle known as the Joint Strike Fighter suffered another setback Friday when the Pentagon grounded the first 51 of 2,400 desired jets.
AP/J. Scott Applewhite
It is bizarre that Chuck Hagel, a war hero with a long record of sensible views on the deployment of military power, gets blocked as the president's nominee to run the Pentagon, while Jack Lew, steeped in Wall Street greed, sails through as Treasury secretary.
AP/Manuel Balce Ceneta
The confirmation hearing of John Brennan to become CIA director began and ended Thursday with questions about his oversight of the drone program that is said to have been responsible for the deaths of at least 2,629 people.
It's unclear which benefits the spouses of gay and lesbian armed services members will receive, but legal experts say there are at least 100 that the Pentagon cannot extend while the Defense of Marriage Act is still being enforced.
AP/Nati Harnik
As Chuck Hagel begins his Senate confirmation hearings Thursday, you can be sure that no senator will ask him about his presence during the machine-gunning of an orphanage in Vietnam's Mekong Delta or the lessons he might have drawn from that incident.
Is the Sahara the newest great threat to the United States—"a terrorist training ground," hotbed of extremism, the new Afghanistan—in the Great War against Islamic terrorism that still preoccupies the American political class and the foreign affairs community?
Photo illustration from an image by Colin Grey (CC-BY)
Last week on Truthdig Radio in association with KPFK: Robert Scheer and Nick Turse on the American doctrine of eradication; women in combat; and the 40th anniversary of Roe v. Wade.
By Clay Bennett —
A new drone-mounted surveillance camera, chillingly described as the "Wide Area Persistent Stare," can see and record, all at once, virtually everything happening at ground level in a medium-sized city.
Truthdig Editor-in-Chief Robert Scheer and the other "Left, Right & Center" panelists discuss whether President Obama's inaugural speech means he's becoming the liberal Ronald Reagan. They also consider whether the Pentagon's lifting of the ban on women in combat is social progress or simply a military necessity.
The Defense Department announced Friday that it has begun firing most of its 46,000 temporary personnel in advance of automatic budget cuts of about $50 billion that are expected in March.
AP/Kristin M. Hall
Mark this as a moment of progress in the struggle for gender equality in America. The Pentagon has announced its plans to let your mother, girlfriend and daughter kill and be killed on a battlefield.
The overall failure of American foreign policy during the first Obama presidency was foreseeable.
Suicides in the U.S. military surged to a record high last year as 349 soldiers—far more than were killed in active combat—took their own lives.
Flickr/New America Foundation
If the neocons in the GOP who brought us the Iraq War and conjured up "weapons of mass destruction" to justify it are against Chuck Hagel for defense secretary, the former Republican senator gets bonus points in my book.
x-ray delta one (CC BY-SA 2.0)
While the Obama administration is pledging to try to curb the wholesale spread of ever more powerful weaponry at home, what is it doing about the same issue abroad where it has so much more power to pursue the agenda it prefers?
The U.S. Army presence is rapidly increasing in Africa, especially in countries with alleged ties to al-Qaida; according to Fox News, teaching children algebra is just another liberal ploy; meanwhile, some researchers have started studying the effects of the "natural experiment" resulting from China's one-child policy. These discoveries and more after the jump.
Whatever Chuck Hagel's perspective on Mideast policy may be, it would be absurd to compare him with the secretary of defense whose hardline hostility toward Israel became notorious during the Reagan administration.
U.S. Army/Sgt. Matthew C. Moeller
Not all of the world—certainly not the Islamic world—wants America's version of global security, which has required repeated American military interventions abroad, provoking guerrilla and terrorist resistance.
By Signe Wilkinson —
Guardian columnist Glenn Greenwald asks "whether [the United States'] endless war [on terror] is the intended result of U.S. actions or just an unwanted miscalculation."
During the halcyon 1990s, we labeled annual congressional temper tantrums for what they were: standard, if boring, budget impasses.
JD Hancock (CC BY 2.0)
Every few years, the intelligence community's "center for long-term strategic analysis" has been intent on producing a document it calls serially Global Trends [fill in the future year]. The latest edition, out just in time for Barack Obama's second term, is Global Trends 2030.
Amidst the White House and congressional theatrics surrounding the so-called fiscal-cliff negotiations, a number of bills were signed into law by President Barack Obama that renew some of the worst excesses of the Bush years.
U.S. Army/Specialist Ken Scar
Christmas has provided a day of distraction from war, the usual condition for most of the world, and the steady-state of the modern American nation, so to speak.
DoD/D. Myles Cullen
If Chuck Hagel is nominated by President Obama to serve as secretary of defense, there will be at least three compelling arguments in his favor.
Official U.S. Navy Imagery (CC BY 2.0)
Seoul is seeking four "advanced" surveillance drones priced at a total of $1.2 billion to gather intelligence on North Korea's activities after the U.S. turns over wartime command of Korean troops—a legacy of the 1950s Korean War—later this decade.
This is the microcosmic lesson of the University of Colorado's recent decision to pay a new football coach $2 million a year. The move - and the reaction to it - is a perfect illustration of America's values, or lack thereof.
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Speaker Dennis Gannon, Fabrizio Gagliardi, Marty Humphrey, and Paul Watson
Affiliation Microsoft Research, University of Virginia, Microsoft Research Connections, Newcastle University
Host Kenji Takeda, Microsoft Research
Duration 01:13:40
Date recorded 8 October 2012
Cloud computing for science is seeing take-up in many disciplines, but many researchers are skeptical. In this panel session, we discuss:
©2012 Microsoft Corporation. All rights reserved.
By the same speakers
Predicting Tornados with Data Driven Workflows: Building a Service Oriented Grid Architecture for Mesoscale Meteorology Research
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text:
Look luxurious for a winter formal event in this Kathy Hilton H24073 evening gown. This dress has fine stones at the shoulders and cutout sleeves with a blouson shape. Sleeves are quarter length with additional embellishment. This gown has a V-neckline and jeweled detail at the center of the bust. The empire waist gives way to a smooth velvet skirt with a full length hem.
Find a lower price and we will match and beat it by 5%
We are an authorized retailer of all the dresses we sell. We only sell 100% authentic dresses.
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text:
See definition in Oxford Advanced Learner's DictionaryLine breaks: hold|over
Pronunciation: /ˈhəʊldəʊvə/
Definition of holdover in English:
nounNorth American
A person or thing surviving from an earlier time, especially someone surviving in office: Young is the only holdover from the 2002 team
More example sentences
- More than two-thirds of the appointees are holdovers from the previous cabinet.
- But in reality, Daylight Savings Time is an archaic holdover from a time when people relied on candles all the time.
- Eight of them are women and 16 are holdovers from the previous Cabinet.
Definition of holdover in:
- US English dictionary
What do you find interesting about this word or phrase?
Comments that don't adhere to our Community Guidelines may be moderated or removed.
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= trending


text:
To modify a reservation, please key in your last name and booking confirmation number below.
Indulge in double Asia Miles when you book a stay at any Pan Pacific hotel.
Welcome the Year of the Monkey with a resplendent buffet spread of Lunar New Year dishes presented across seven live food theatres at Edge.
Indulge in complimentary breakfast and an auspicious red packet credit of USD38 per stay to enjoy a fine selection of dining and wellness facilities when you book our Lunar New Year offer.
Pacific Marketplace brings you on a tour around Asia with the latest selection of dishes inspired by regional delicacies.
Book a Residential meeting and benefit from a variety of exclusive privileges. The larger the group size, the greater the privileges.
This Valentine's Day, bask in the spirit of love with culinary creations at Edge and Keyaki to celebrate romance.
In celebration of Pan Pacific Singapore 30th Anniversary, book our exclusive staycation offer and enjoy breakfast at Edge, and spa and dining credits.
Experience a romantic culinary treat with Master Chef Hiroshi Ishii's delicately crafted kaiseki presentation at Keyaki.
This Valentine's Day, bask in the spirit of love and indulge in a romantic dining experience at Edge with your significant other.
All prices quoted are subject to GST and service charge.


text:
According to the International Energy Agency, the world's energy demands could increase by 50% by 2030. With the distressing decline of natural gas and oil sources, the world has long known and understood for the past decade the impending potential for a global energy crisis. James Greenberger in The Real Energy Crisis argues that today the urgency to solve the energy crisis has slowed in momentum and has been replaced with complacency and even optimism as politicians and experts suggest that energy independence is within our reach.
Greenberg argues that this complacency has manifested from innovations oil digging technology, with the production of new technologies including hydraulic fracturing – better known as "fracking" – and horizontal drilling, to obtain new sources of petrolium. The method of fracking involves the drilling deep into rock and then pumping large quantities of water into the hole which would then fracture the surrounding sediment. The fissures which develop from the fracking then allow the natural gases trapped within the rock to escape through hole for collection.
The real energy crisis suggested by Greenberg however "is neither a gelogic crisis nor a strategic crisis. The real energy crisis is a slow growth crisis'. That is, even though technology has provided a means to recover quantities of oil resources the cost of doing so is staggering and only exacerbates the already problematically high prices for oil, hence the problem becomes cyclical. Furthermore, these methods are only a temporary fix for energy dependancy in the U.S. as these resources are finite in themselves. The solution to all this, according to Greenberg, is the same solution settled on five years ago, that is through substituting petroleum in the transportation sector with different fuels and battery technology. Ultimately however it must be understood that the nature of the energy crisis is not just an issue of finding new substitutions for energy but also an economic one due to the high cost for implementing and innovating new technologies.
Greenberger J., The Real Energy Crisis, 2012, viewed June 29th 2013, http://theenergycollective.com/jim-greenberger/141741/real-energy-crisis


text:
03 Jan 2014
LEONARD CURTIS was appointed to more insolvency cases than any other firm in 2013, overtaking KPMG and Begbies Traynor, according to London Gazette data.
In the Top 20 firm appointments for insolvencies Leonard Curtis lead the table with 129, followed by 116 for Begbies Traynor and 105 from Duff & Phelps, (see chart below).
Further reading
Last year, the top three consisted of Begbies Traynor with 148 appointments, 129 from KPMG and 111 from Leonard Curtis.
Zolfo Cooper administrators were appointed to 101 cases in 2012, but failed to appear on the table in 2013. FRP Advisory climbed three places to fourth and KPMG slipped to fifth.
The figures were compiled by Geoff Swire based on all London Gazette notices. Insolvencies have dropped in the last year among the Top 20 with 1,246 in 2013 compared to 1,482 in 2012.
Neil Bennett, Leonard Curtis managing partner said: "The latest figures are testament to our depth of services and our innovative and reactive staff."
Total administrations across all sectors is down 11% according to research by Deloitte. According to the Big Four firm, there were 1,629 administrations in total in 2013, compared with 1,833 in 2012. In particular retail administrations were down 6% to 183 in 2013.
Sectors which saw a particular decrease were property and construction with a 17.5% decline, hospitality and leisure 17.5% and 4% in manufacturing. However, outside of retail healthcare and social services saw an increase of 7%.
Lee Manning, restructuring services partner at Deloitte, said: "The high street has undergone a re-balancing, and this is what is being reflected by these figures.
"Christmas trading appears to have been reasonable, though not spectacular as customers opted to stay away from the high street in favour of click and collect. It is essential that retailers address the fundamental issues affecting the industry. 2014 is likely to be marked by further closure programmes, both within and outside of formal insolvency processes.
To view previous years' tables, click here.
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text:
Quotes & Info
|CMCSA > SEC Filings for CMCSA > Form 8-K on 18-Oct-2012
|All Recent SEC Filings
Regulation FD Disclosure
As described more fully below, Comcast Corporation and its wholly-owned subsidiary, Comcast Holdings Corporation ("Comcast Holdings"), do not anticipate that the recently announced Sprint Softbank transaction will result in any changes to the interest paid or amounts due at maturity on Comcast Holdings' 2.0% Exchangeable Subordinated Debentures due 2029 (CUSIP 200300507, NYSE: CCZ) or on its 2.0% Exchangeable Subordinated Debentures due November 2029 (CUSIP 200300606) (collectively, the "ZONES").
On October 15, 2012, Sprint Nextel Corporation announced that it has entered into an Agreement and Plan of Merger with Softbank Corp., pursuant to which Softbank seeks to acquire control of Sprint Nextel through a direct wholly owned Softbank subsidiary ("New Sprint"). Among other things, the Sprint Softbank transaction contemplates an exchange offer in which each share of Sprint Nextel's common stock will be converted, at the shareholder option, into $7.30 in cash, one share of New Sprint common stock, or a combination of cash and stock. The Sprint Softbank transaction is subject to a vote by Sprint Nextel shareholders as well as other conditions. The terms of the Sprint Softbank transaction can be amended by agreement of the parties thereto.
Comcast Holdings has concluded that, as currently structured, the Sprint Softbank transaction constitutes a "Reference Share Offer" for purposes of the ZONES. Subject to market conditions and possible future changes in the terms of the Sprint Softbank transaction, Comcast Holdings expects to elect to increase the "Early Exchange Ratio" of the ZONES from 95% to 100% during the pendency of the Sprint Softbank transaction rather than making a "Reference Share Offer Adjustment". This means that there will be no changes in the payment terms of the ZONES, except that upon consummation of the Sprint Softbank transaction the Reference Shares underlying each ZONES will change from shares of Sprint Nextel common stock to an equivalent number of shares of New Sprint common stock. In particular, no "Additional Interest" will be paid in connection with the Sprint Softbank transaction.
An increase in the Early Exchange Ratio to 100% would allow a holder of the ZONES to exchange its ZONES for the full "Exchange Market Value" of the Reference Shares underlying its ZONES. As of the date hereof, the "Contingent Principal Amount per ZONES" substantially exceeds the Exchange Market Value of the Reference Shares per ZONES. Accordingly, Comcast Holdings does not anticipate that any ZONES will be exchanged in connection with the Sprint Softbank transaction.
Capitalized terms used but not otherwise defined in this Current Report have the meanings set forth in the ZONES.


text:
Music blog
Johnny Depp Gone Mad Apocalyptic Z Anime Comes Out Of Shell Absolute Magic Of Rickman's Voice MORE ›
Lyrics/song texts are property and copyright of their owners and provided for educational purposes only.
Sunday School Lyrics by Natas
Sunday School by Natas
See, I don't know what you beliven in, but I hope you believen in me
Nigga fuck yo G.O.D, my religion is reality, see
I don't wanna go to church (no I don't wanna go to church) X3
I don't wanna go to church (no I don't wanna go)
See, I can't step up in yo cathedral
I might bleed you
I don't need you to tell me who made me
I don't believe you
My thoughts bust
Who can I trust
What's the fuckin purpose
If I took a little ride on that church bus
I'd cuss out the rev
Bust and size out his head
My holy bible collects dust
Cause it's never been read
So what is evil
What is my evil
I see you people hate me
Cause I wont step up in your steeple
But oh no!
I'm sick in the head
So I tried to kill a priest
But now I'm killing time
I'm in the belly of the beast
No study the bible
Bloody rifle
The disciple of NATAS
Contemplatin suicide
Murder ride
And I'm the dri-va
Bloods in my mouth
Mixed with my sali-va
I'm screamin out Jesus Christ
Bloody murder, crucified
When I close my eyes
Got visions of when he died
Motha fuck the reverin
I've never seen a church
I never been to church
I never liked church
So what is this sac religious mohta fucka
Sayin to me
Runnin around
Screamin out blaz 4 me
The holy bible burns my hands when I touch it
I can't clutch it
So motha fuck it
I do with out it
Simple reasons keep me from sayin the lords prayers
Truth or dares
Who cares


text:
My Entry for the Support Challenge on Emotiholics
And also part of the Visual Purpose NaNoEmo - NaNoEmo
My NaNoEmo Folder
And also part of the Visual Purpose NaNoEmo - NaNoEmo
August Emoticon Challenge- SUPPORT! + 4 ENTRIES It's here!
Welcome to Emotiholics' 1st ever Emoticon Challenge! This month's theme is....
Here's how it's gonna go down (rules)
All entries must in some way fit the theme. They can be as strictly or loosely interpreted as you want, just so long as you can explain the relevance to me if I don't get it
All entries must be made/submitted to the group contest folder on or after the contest start (August 4th, 2014) and before the contest end (August 31st at 11:59:59 PM Eastern Time, UTC -5:00)
That being said, you must be a member of Emotiholics. All requests are auto-accepted.
Better Late than NaNano - VPNaNoEmoThe fun begins August 1st!!
Last year we ran a special NaNoEmo in June. It was solely for Visual Purpose Emoticons. What does that mean? It means emoticons that are created to look at, not for use in chats or comments. Basically, pretty emoticon pictures. However, visual emotes can also include useful things like icons, stamps, etc. The key is that care is taken to create an emoticon "scene", usually with a detailed background.
I am gonna defer to the journal written last year by Synfull. It outlines what the challenge is about and how to participate. The good thing about VP NaNoEmo is that the goal is not one-a-day, but one-a-week, and smaller emote scenes (like avatars) count. So, get boned up, and if you're ready to participate, sign up.
Note that I know we're 2 months late, and notice of this is really last minute. My apologies. However, NaNo has always been a big motivator in the emoticon community and I hope it inspires a few old-timers, and newcomers, t
My NaNoEmo Folder
Awwww, this is so cute!
Love the smoothness of this. The idea is adorable
First I thought the hand was it's mouth xD then I looked closer and was like aaaah still really nice animation, me likey
Awesome. :'D
Very smooth animation and the idea is great. (:
Very smooth animation and the idea is great. (:
Makes me think of my mum :3
Very creative!
Aw, very cute. Literal and figurative too!
I think the only thing that would have made it better would be if the purple emote would have moved earlier on. Until it moved at the end, I just thought it was a big purple moon or something o.o
I believe that if one would take this emote and put it in a zig-zag pattern, the blue one would go up and up and up for eternity!
This is really adorable, the little emote and the big one look like they have a lot of fun, and it sends a nice message about helping each other too
awe so cute!
so cute
so cute
What a great message! I love how fluid it is too


text:
From left Peter Trebilco, project manager for Ringwood Foodbank, Verwood mayor Pat Morrow, David Kratzke, organiser for Verwood Distribution Centre and Claire Skelley, volunteers coordinator and trustee
/ News
A NEW foodbank will open in Verwood tomorrow.
Ringwood Foodbank will open its second distribution centre in the Verwood United Reformed Church in Manor Road at 11.30am.
The new centre will provide emergency food aid as well as information and friendship for individuals and families in crisis in East Dorset.
Ringwood Foodbank has been operating for eleven months and has given food aid to more than 450 adults and children.
Some 46 volunteers have stepped forward to help run the new centre, and the Revd Julian Macro and Alan Harley have provided the premises at the United Reformed Church.
Many people have donated food and funds, and Churches Together in Verwood is distributing an information leaflet to households in the area.
The Verwood Distribution Centre will be open each Monday, Wednesday and Friday between 11.30am and 1.30pm.
Call 01425 600134 or go to www.ringwood.foodbank.org.uk for further details.
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text:
Does the FB Like button work in email newsletters? Or will this only be used for a website?
A friend was asking me if you can put these in an email, and like the email (putting any URL in of course) will it work correctly as it would on a website? Would the information be updated if Person A opened email, liked the email, then Person B opened up the same email on another system will they see the increase in the total number of people liking it?


text:
Tooth fairy fees
Local parents discuss how much money they leave for their children under their pillows when they lose their teeth. A recent study released by Visa Inc. states that parents are giving their children more money than in years past. Videojournalist: Chris Ware (Aug. 30, 2013)
Cops: 3 hurt in crash that closes eastbound Sunrise Highway in Copiague Suffolk County to get brunt of storm Winter storm warning for Suffolk, advisory for Nassau National bagel eating champion crowned Up to 8 inches of snow expected from 5am-6pm Monday Early morning snow in Garden City Forecast: Winter storm warning for Suffolk, advisory for Nassau Dowling College starts drone training program Suffolk County Police Department unveils reforms to internal affairs Watch LI's Malcolm Pridgeon sign with Ohio State Three barn-like Long Island homes Body found behind Brentwood apartments


text:
Tod and Buz wind up in the middle of a bitter family when they are boarders in a woman's house while working at an Oregon lumber mill.
Tod enlists horror-film actors (Boris Karloff, Peter Lorre, Lon Chaney Jr.) to get back at Buz, who won't share his hotel escort duties.
A vicious criminal (Rod Steiger) escapes police custody and brings hostage Buz along on his hunt for long-hidden loot in Portland, Ore.
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|Marino with a recently restored historical jacket at the
Heimatmuseum Warnemünde in Rostock, Germany
|Daniel Karvonen's Mini-Class "Finnish Origins: Linguistics & Genetics"
|Rick McCormick's Mini-Class "Divine Decadence: Berlin in the Roaring '20s"
|Post-It Notes from the Mini-Class "World Cafe:
Contemporary Language Evolution & Impact of New Technologies"
"The Alumni Reunion held on April 25th was fantastic! It was a great opportunity to reunite with old friends and meet new ones with a common interest in European languages. It was also nice to meet students in an environment where alumni could share their experience and application of language skills outside of academia to assure students that there are opportunities in the business world for language grads. In addition, the workshops provided a great way for alumni to get a taste of the classroom experience after so many years away from school."
- Blaine Bos
B.A. 1976, History and Dutch
Vice President, Health Care Modernization at Optum
"The Language Reunion was an excellent way to return to campus, learn what current students are doing, connect with friends, and network with like-minded language grads. I particularly enjoyed the thoughtfully planned mini-sessions that covered everything from culture, food and travel, to current events and politics. And, for an early Saturday morning start, the coffee was extra black and strong – fitting for the euro-minded crowd! I hope there are other similar events in the future."
- Eric Brotten
B.A. 2003, German and Economics
Vice President, Global Health Products & Solutions at Optum International
"The reunion was a great opportunity to come back to campus and revisit our classrooms and professors. I felt like I was in college again! I look forward to attending this event again in years to come."
- Hannah Guenveur
B.A. 2010, German and Global Studies
Associate Business Systems Analyst - HR at Ecolab
"It was truly a joy to return to the halls of Folwell, bond with fellow alumni, and best of all, listen to language department professors share their expertise without having to worry about taking a test at the end!"
- John Vaughan
B.A. 2011, German
B.S. 2011, Finance and International Business
Consultant at Deloitte Consulting
"The Language Alumni Reunion was fantastic. Returning to Folwell Hall after two decades really opened my eyes to how far I had come since graduating. As a senior about to graduate in 1994, the question I heard most often was: "A degree in Scandinavian Languages? What are you going to do with that?" At that time, I honestly didn't know and was quite nervous about my prospects, as well. The worry proved to be needless. Twenty years later, I am a successful language professional and the reunion brought together nearly two hundred other language alumni who have succeeded in many industries and professions with their language degrees.
"The format of the reunion made it easy to connect with other attendees. Sitting in the newly renovated classrooms for the mini-courses was a thrill. There was definitely a nostalgic quality about taking a seat in Folwell Hall for a course with the some of the same instructors I had twenty years ago. At the same time, it was fresh and fun. I hope the reunion can become a regular event for language alumni in the future, perhaps even in an expanded format."
- Kyle Vraa
B.A. 1994, Scandinavian Languages
Owner, Vraa Translation
|"Pleasure & Distraction" Homepage
|Lynn Strom, German teacher
at Watertown-Mayer High School,
and Grace Kroeger,
CIS scholarship winner
at the CIS Field Day on April 22
For 105 years, a sculpture of German literary giant Johann Christoph Friedrich von Schiller (1759-1805) has presided over the gateway to Como Park. It was commissioned from artist Ignatius Taschner by St. Paul's German American community and gifted to the City in 1907. Having braved over a century of Minnesota winters, this cultural treasure has been completely restored by Public Art Saint Paul.
The community is invited to rededicate the sculpture with triumphant fanfare and choral voices on Saturday, May 11th at 10:00am. The rededication will be held at the Schiller sculpture site near the Como Park gateway at Lexington and Eastbrook drive. In case of rain, the program will move indoors to the Como Park Visitor Center Auditorium.
A Minnesota Chorale performance of Ode to Joy from Beethoven's 9th Symphony will celebrate the sculpture's rededication. Saint Paul City Councilmember Amy Brendmoen will officiate, along with Honorary German Consul Christa Tiefenbacher Hudson, Saint Paul Parks and Recreation Director Michael Hahm, and Public Art Saint Paul President Christine Podas-Larson. University of Minnesota Professor Rick McCormick will speak of Schiller and students of the Twin Cities German Immersion School will recite a Schiller poem.
|Photo: Jackie Listemaa, Mariah Swanson, Amara Sankhagowit, and Heidi Miller study Swedish at the University of Minnesota.
|Photo: Students Mariah Swanson and Ben Wils with one of the many learning-aids they use during lessons


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Minibus, Hong Kong
13 Reviews
13 Reviews
Red Striped Minibuses are small passenger vans with maximum accommodation of 16 people. Generally they serve areas which are less accessible by buses. Passengers may get on or off anywhere en route.
Routes - not always fixed
Fares - Non-fixed prices
When to Pay - Pay as you get off
Payment - Small change can be given or use octopus card.
You hail a minibus just as you do with an ordinary taxi, but cannot hail or stop at any bus stops.
Most tourist might not even know about him but he is as much part of HK's street life as the double-deckers and taxis: the Minibus!
There are two different kinds of Minibuses:
1. Green roof (fixed routes - pay when entering)
2. Red roof (no fixed routes - pay when alighting)
For the green buses, check out the below website for their routings. It's possible to get off almost everywhere (just shout "Stop!" to the driver) as long as it's on the route.
As for the red ones: except the fact that you can ask them to drop you off in front of your door (if the driver agrees to it), not even locals exactly know the routing and usually ask their way around. Wouldn't recommend to try unless you've got some local help!
Take Minibus no. 1 from Central (Hong Kong station bus terminus, in between IFC 2 and the Four Seasons Hotel) to The Peak. It's the cheapest way to get there from Central (8.00HKD), usually faster than the regular bus, as exciting... and extremely local!
Minibuses are often known as the "poor people's taxi" & have a maximum of 16 seats. There are two types of minibuses: red & green.
Green minibuses operate at fixed routes with fixed fares. Red minibuses, on the other hand has no schedule or fixed routes. Most of them serve as short connecting lines between MTR stations, KCR terminals, shopping centres or residental areas.
As the routes(have to ask driver), signs (often in Chinese) & customer service (or the lack of it) are often very confusing, travellers & locals all have trouble using this form of transportation.
So good luck if you are planning to use the minibus!
Minibus in Hong Kong is classified into red minibus and green minibus. Green minibus travels a rather short distance, normally travel to places where no MTR reaches. Red minibus travels a longer distance compared to the green one. And the route is not fixed. It varies with the time you take the minibus. Both the red and green minibus carries 16 passengers for each ride.
The green minibus accepts cash and the octopus card. You need to pay the fare in the minibus once you get it. Whereas the red minibus accepts cash only. You need to pay the fare before you get off the minibus. The fare is shown in front of the minibus.
For both the red minibus and the green minibus, you need to tell the driver where you are going to get off. Otherwise the driver will just pass through the place you are going to get off.
There are no specific minibus stops. You may just get the minibus at the place where stopping of the minibus is not prohibited.
In general, I do not recommend travellers to take the minibus. First, passengers need to tell the driver where to get off. For a traveller, it is difficult to know where to get off in the minibus. It is even difficult for a local to tell the driver where to stop. Also, normally, the bus and the MTR goes through all the places travllers visit. It is not necessary for a traveller to take the minibus, except you would like to experience it. And the distination of the minibus shown in the minibus is written in Chinese only. It is not convenient for travellers to get the correct minibus.
The only advantage of taking the minibus is that it is fast. When the bus takes 30 mins, the minibus takes only 10 mins. But the disadvantage is that it is a bit dangerous. The minibus sometimes is driven faster than the required speed. You may get more information in the general tip part.
The red and green Minibuses that you see rushing along Hong Kong streets (and trust me sometimes you need to get out of their way) are known as Public Light Buses.
These buses transport mainly locals to outlying residential areas of Hong Kong not fully serviced by conventional buses, or to areas where passenger numbers do not necessitate using a larger bus. There are approximately 4400 licenced PLB's and at times it seems they are all on the streets at the same time so take care when stepping off the footpath.
I have never used one myself simply because the MTR takes me close enough to everywhere I want to go and do I enjoy walking the rest of the way to my destination. Its important to know something about the area you are going to because when you get on you need to tell the driver where you want to get off. I would personally find this too difficult if I didnt know the area well.
NOTE: If you decide to use a Red Minibus be aware that because they are unregulated drivers they do not need to follow a fixed route or timetable and may even set their own fares. I heave heard that fares rise dramatically during inclement weather when demand is high. Fares are payable by cash only.
Octopus cards can be used on Green Minibuses.
An even cheaper alternative to Bus/ferry/MTR/Tram in Hong Kong is the minibus. They are everywhere and run various routes throughout Hong Kong, they are a lot cheaper and probably quicker than most modes of public transport. You should really be able to speak some basic Cantonese or be with some who does, if travelling on these, as all destinations are in Chinese and drivers normally only speak Cantonese. You can use the Octopus card on the minibus also.
Also known as "maxicabs"; there are 2 kinds - red top, and green top. Green top have fixed route, while Red Top don't. They are 16 seat public vans. Most of them serve as short connecting rides between MTR stations, train terminals, shopping areas and residential areas.
You can check this official page for the minibus route:
As to where they all go, good luck! Even the locals don't know except the routes they frequent. I suspect there is no web site on all the routes either.
Taking minibus is more convenience as the minibus as and where you wanted compare to the Link Bus. It is only HKD18 from Gold Cost to Mongkok.
The minibus condition is tip top. The seats are clean and the air condition is good. They do not have any schedules. They come like every 15-20mins.
Link bus is good to take if your are travel to a nearby distance. They follow schedules.
On top of that, MTR is another choice for mode of transport. Try to avoid taking cab unless some circumstances that you cannot avoid. The cab fee that you pay for 1 trip good enough to pay for your whole day bus or MTR transportation fee.
Besides the Larger Double Decker Public Buses, Hong Kong also has many Public Minibuses that is more popular with locals than with tourists and is another cheap means of transport.
There are two kinds of Mini Buses, the Green Van, with scheduled service, fixed routes and fixed fares, usually have fixed station. Under the control of the government and the Red Van,Usually with scheduled service, routes and fares, but drivers may adjust to the optimum route according to the road condition, and fares may also be adjusted (examples will be during bad weather like a typhoon). Not absolutely under the control of government.
the best deal here is that you can your the all around Octopus Card to Pay for your bus fares. Like the Big Public Buses, the Mini Buses in Hong Kong are self-service ticketing and change is not given. Generally, ticket fare is displayed on information boards at the bus stops. Passengers should ensure they are carrying the correct change before boarding or using an Octopus Card to pay the ticket fare. When you are approaching your destination stop, press the electronic buttons fixed in the bus, to advise the driver that you want to get off. Otherwise, the driver may not stop.
Most Public Buses start from 6:00 am to 12:00 am on most routes.
The Mini bus service to Shenzhen is easy fast and convient. Here is how it works.
As you leave customs, walk to the left toward the "A" section of desks. You will see a counter offering service to China. You pay them about 170 HK dollars and walk toward the first counter in the "A" section. A woman there will direct you to the exit to the limo service. A second woman will point you to the elevator down to the next level. When you walk out of the elevator you will see the minibuses.
A man will tell you to take a seat and fill out the health form required for China. He will call when your driver arrives. the bus will take you across Hong Kong and over the new Shenzhen Bay Bridge. At the China side, you will drive into the HK Immigration booth, Customs, China Immigration and China Customs. You never leave the car! From there the driver will take you to a small street where you transfer to a minibus with Chinese plates and a steering wheel on the left side. They will take you to your hotel or final destination.
I have included pictures to help as a guide. Take a look and enjoy the ride. It is only 1 hour from the HK airport to Shenzhen Holiday Inn, Dong Hua hotel!
Red minibuses look like yellowish vans with red roofs. They run 24 hours (compared to the green-roof green buses, which run only from early morning to around midnight).
The red minibuses are fast. To stop you need to know your route.
In Wanchai, there are minibuses that run from Wanchai to Mongkok--I forget the cross street.
In LKF there are minibuses that run from LKF (on Queens Road and D'Aguilar) to Mongkok.
In Mongkok, near the beginning of the Temple Street Market, there are red minibuses that run to the north west, to Yuen Long. There are also red minibuses there that run to the east, to Saikung.
The minibus is 16 seats and you have to read out where to go. For green minibus, there are usaully a fix route. While for red minibus, there may or may not be. You can to yell out when you want to get off and flag the bus along the road if you want aboard.
There are two types of minibus in Hong Kong, which varies a bit but they both take 16 passengers.
- Route fixed
- Price awkward with cents ($2.4, $3.7, $5.4 etc)
- Usually possible to pay with octopus
- Fast especially in mid-night
- Pay when on board, exact fare expected.
- Route flexible
- Drivers are world-class: well-developed radio-communication network, always take the fastest way.
- Price are exact dollars ($2.0, $6.0, $12.0 etc)
- Preferably pay when on board for fastest possible trip.
- Changes available. Octopus usually not accepted except a few well-organized routes (for example Sheung Wan -> Tsuen Wan)
- After mid-night, sit sight because the world-class driver will drive at full speed.
Remember to yell "Yaau Lockh" when you want to exit.
Get an instant answer from local experts and frequent travelers
For tourists (particularly those who do not know chinese at all), I would not recommend red minibuses. Green minibuses are better as they have fixed stops. Red ones are more for those who know the route well, and know exactly (and have to ask the driver) where to stop.
There are some red minibuses where the handlebars are off (our joke is that they were pulled off by passengers during rocky roads). Honestly taking bus/MTR/Tram/etc is safer than minibus (particularly red ones after midnight), drivers on red minibuses are paid on number of trips.
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Are you Frédéric Saudou?Claim your profile
Publications (90)704.29 Total impact
Article: Huntingtin proteolysis releases non‐polyQ fragments that cause toxicity through dynamin 1 dysregulation[Show abstract] [Hide abstract]
ABSTRACT: Cleavage of mutant huntingtin (HTT) is an essential process in Huntington's disease (HD), an inherited neurodegenerative disorder. Cleavage generates N‐ter fragments that contain the polyQ stretch and whose nuclear toxicity is well established. However, the functional defects induced by cleavage of full‐length HTT remain elusive. Moreover, the contribution of non‐polyQ C‐terminal fragments is unknown. Using time‐ and site‐specific control of full‐length HTT proteolysis, we show that specific cleavages are required to disrupt intramolecular interactions within HTT and to cause toxicity in cells and flies. Surprisingly, in addition to the canonical pathogenic N‐ter fragments, the C‐ter fragments generated, that do not contain the polyQ stretch, induced toxicity via dilation of the endoplasmic reticulum (ER) and increased ER stress. C‐ter HTT bound to dynamin 1 and subsequently impaired its activity at ER membranes. Our findings support a role for HTT on dynamin 1 function and ER homoeostasis. Proteolysis‐induced alteration of this function may be relevant to disease.
Article: Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer's disease early phenotypes[Show abstract] [Hide abstract]
ABSTRACT: It is suspected that excess of brain cholesterol plays a role in Alzheimer's disease (AD). Membrane-associated cholesterol was shown to be increased in the brain of individuals with sporadic AD and to correlate with the severity of the disease. We hypothesized that an increase of membrane cholesterol could trigger sporadic AD early phenotypes. We thus acutely loaded the plasma membrane of cultured neurons with cholesterol to reach the 30% increase observed in AD brains. We found changes in gene expression profiles that are reminiscent of early AD stages. We also observed early AD cellular phenotypes. Indeed we found enlarged and aggregated early endosomes using confocal and electron microscopy after immunocytochemistry. In addition amyloid precursor protein vesicular transport was inhibited in neuronal processes, as seen by live-imaging. Finally transient membrane cholesterol loading lead to significantly increased amyloid-beta42 secretion. Membrane cholesterol increase in cultured neurons reproduces most early AD changes and could thus be a relevant model for deciphering AD mechanisms and identifying new therapeutic targets.
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ABSTRACT: Although dominant gain-of-function triplet repeat expansions in the Huntingtin (HTT) gene are the underlying cause of Huntington disease (HD), understanding the normal functions of nonmutant HTT protein has remained a challenge. We report here findings that suggest that HTT plays a significant role in selective autophagy. Loss of HTT function in Drosophila disrupts starvation-induced autophagy in larvae and conditional knockout of HTT in the mouse CNS causes characteristic cellular hallmarks of disrupted autophagy, including an accumulation of striatal p62/SQSTM1 over time. We observe that specific domains of HTT have structural similarities to yeast Atg proteins that function in selective autophagy, and in particular that the C-terminal domain of HTT shares structural similarity to yeast Atg11, an autophagic scaffold protein. To explore possible functional similarity between HTT and Atg11, we investigated whether the C-terminal domain of HTT interacts with mammalian counterparts of yeast Atg11-interacting proteins. Strikingly, this domain of HTT coimmunoprecipitates with several key Atg11 interactors, including the Atg1/Unc-51-like autophagy activating kinase 1 kinase complex, autophagic receptor proteins, and mammalian Atg8 homologs. Mutation of a phylogenetically conserved WXXL domain in a C-terminal HTT fragment reduces coprecipitation with mammalian Atg8 homolog GABARAPL1, suggesting a direct interaction. Collectively, these data support a possible central role for HTT as an Atg11-like scaffold protein. These findings have relevance to both mechanisms of disease pathogenesis and to therapeutic intervention strategies that reduce levels of both mutant and normal HTT.
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ABSTRACT: Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder resulting from polyglutamine expansion in the huntingtin (HTT) protein and for which there is no cure. Although suppression of both wild type and mutant HTT expression by RNA interference is a promising therapeutic strategy, a selective silencing of mutant HTT represents the safest approach preserving WT HTT expression and functions. We developed small hairpin RNAs (shRNAs) targeting single nucleotide polymorphisms (SNP) present in the HTT gene to selectively target the disease HTT isoform. Most of these shRNAs silenced, efficiently and selectively, mutant HTT in vitro. Lentiviral-mediated infection with the shRNAs led to selective degradation of mutant HTT mRNA and prevented the apparition of neuropathology in HD rat's striatum expressing mutant HTT containing the various SNPs. In transgenic BACHD mice, the mutant HTT allele was also silenced by this approach, further demonstrating the potential for allele-specific silencing. Finally, the allele-specific silencing of mutant HTT in human embryonic stem cells was accompanied by functional recovery of the vesicular transport of BDNF along microtubules. These findings provide evidence of the therapeutic potential of allele-specific RNA interference for HD.
Article: Activation of IGF-1 and Insulin Signaling Pathways Ameliorate Mitochondrial Function and Energy Metabolism in Huntington's Disease Human Lymphoblasts[Show abstract] [Hide abstract]
ABSTRACT: Huntington's disease (HD) is an inherited neurodegenerative disease caused by a polyglutamine repeat expansion in the huntingtin protein. Mitochondrial dysfunction associated with energy failure plays an important role in this untreated pathology. In the present work, we used lymphoblasts obtained from HD patients or unaffected parentally related individuals to study the protective role of insulin-like growth factor 1 (IGF-1) versus insulin (at low nM) on signaling and metabolic and mitochondrial functions. Deregulation of intracellular signaling pathways linked to activation of insulin and IGF-1 receptors (IR,IGF-1R), Akt, and ERK was largely restored by IGF-1 and, at a less extent, by insulin in HD human lymphoblasts. Importantly, both neurotrophic factors stimulated huntingtin phosphorylation at Ser421 in HD cells. IGF-1 and insulin also rescued energy levels in HD peripheral cells, as evaluated by increased ATP and phosphocreatine, and decreased lactate levels. Moreover, IGF-1 effectively ameliorated O2 consumption and mitochondrial membrane potential (Δψm) in HD lymphoblasts, which occurred concomitantly with increased levels of cytochrome c. Indeed, constitutive phosphorylation of huntingtin was able to restore the Δψm in lymphoblasts expressing an abnormal expansion of polyglutamines. HD lymphoblasts further exhibited increased intracellular Ca2+ levels before and after exposure to hydrogen peroxide (H2O2), and decreased mitochondrial Ca2+ accumulation, being the later recovered by IGF-1 and insulin in HD lymphoblasts pre-exposed to H2O2. In summary, the data support an important role for IR/IGF-1R mediated activation of signaling pathways and improved mitochondrial and metabolic function in HD human lymphoblasts.
Article: Mood disorders in Huntington's disease: from behavior to cellular and molecular mechanisms. Front Behav Neurosci 8:135[Show abstract] [Hide abstract]
ABSTRACT: Huntington's disease (HD) is a neurodegenerative disorder that is best known for its effect on motor control. Mood disturbances such as depression, anxiety, and irritability also have a high prevalence in patients with HD, and often start before the onset of motor symptoms. Various rodent models of HD recapitulate the anxiety/depressive behavior seen in patients. HD is caused by an expanded polyglutamine stretch in the N-terminal part of a 350 kDa protein called huntingtin (HTT). HTT is ubiquitously expressed and is implicated in several cellular functions including control of transcription, vesicular trafficking, ciliogenesis, and mitosis. This review summarizes progress in efforts to understand the cellular and molecular mechanisms underlying behavioral disorders in patients with HD. Dysfunctional HTT affects cellular pathways that are involved in mood disorders or in the response to antidepressants, including BDNF/TrkB and serotonergic signaling. Moreover, HTT affects adult hippocampal neurogenesis, a physiological phenomenon that is implicated in some of the behavioral effects of antidepressants and is linked to the control of anxiety. These findings are consistent with the emerging role of wild-type HTT as a crucial component of neuronal development and physiology. Thus, the pathogenic polyQ expansion in HTT could lead to mood disorders not only by the gain of a new toxic function but also by the perturbation of its normal function.
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ABSTRACT: Huntington's disease (HD) is an autosomal dominant disease caused by an expansion of CAG repeats in the gene encoding for huntingtin. Brain metabolic dysfunction and altered Akt signaling pathways have been associated with disease progression. Nevertheless, conflicting results persist regarding the role of insulin-like growth factor-1 (IGF-1)/Akt pathway in HD. While high plasma levels of IGF-1 correlated with cognitive decline in HD patients, other data showed protective effects of IGF-1 in HD striatal neurons and R6/2 mice. Thus, in the present study, we investigated motor phenotype, peripheral and central metabolic profile, and striatal and cortical signaling pathways in YAC128 mice subjected to intranasal administration of recombinant human IGF-1 (rhIGF-1) for 2 weeks, in order to promote IGF-1 delivery to the brain. We show that IGF-1 supplementation enhances IGF-1 cortical levels and improves motor activity and both peripheral and central metabolic abnormalities in YAC128 mice. Moreover, decreased Akt activation in HD mice brain was ameliorated following IGF-1 administration. Upregulation of Akt following rhIGF-1 treatment occurred concomitantly with increased phosphorylation of mutant huntingtin on Ser421. These data suggest that intranasal administration of rhIGF-1 ameliorates HD-associated glucose metabolic brain abnormalities and mice phenotype.
Article: S.04.03 BDNF/TrkB signaling, axonal and dendritic transport and neurodegeneration in Huntington's disease
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ABSTRACT: Emerging evidence suggests that the dysregulation of fast axonal transport (FAT) plays a crucial role in several neurodegenerative disorders. Some of these diseases are caused by mutations affecting the molecular motors or adaptors that mediate FAT, and transport defects in organelles such as mitochondria and vesicles are observed in most, if not all neurodegenerative disorders. The relationship between neurodegenerative disorders and FAT is probably due to the extreme polarization of neurons, which extend long processes such as axons and dendrites. These characteristics render neurons particularly sensitive to transport alterations. Here we review the impact of such alterations on neuronal survival. We also discuss various strategies that might restore FAT, potentially slowing disease progression.
Article: Huntingtin Acts Non Cell-Autonomously on Hippocampal Neurogenesis and Controls Anxiety-Related Behaviors in Adult Mouse[Show abstract] [Hide abstract]
ABSTRACT: Huntington's disease (HD) is a fatal neurodegenerative disease, characterized by motor defects and psychiatric symptoms, including mood disorders such as anxiety and depression. HD is caused by an abnormal polyglutamine (polyQ) expansion in the huntingtin (HTT) protein. The development and analysis of various mouse models that express pathogenic polyQ-HTT revealed a link between mutant HTT and the development of anxio-depressive behaviors and various hippocampal neurogenesis defects. However, it is unclear whether such phenotype is linked to alteration of HTT wild-type function in adults. Here, we report the analysis of a new mouse model in which HTT is inducibly deleted from adult mature cortical and hippocampal neurons using the CreER(T2)/Lox system. These mice present defects in both the survival and the dendritic arborization of hippocampal newborn neurons. Our data suggest that these non-cell autonomous effects are linked to defects in both BDNF transport and release upon HTT silencing in hippocampal neurons, and in BDNF/TrkB signaling. The controlled deletion of HTT also had anxiogenic-like effects. Our results implicate endogenous wild-type HTT in adult hippocampal neurogenesis and in the control of mood disorders.
- [Show abstract] [Hide abstract]
ABSTRACT: Huntington disease (HD) is associated with early psychiatric symptoms including anxiety and depression. Here, we demonstrate that wild-type huntingtin, the protein mutated in HD, modulates anxiety/depression-related behaviors according to its phosphorylation at serines 1181 and 1201. Genetic phospho-ablation at serines 1181 and 1201 in mouse reduces basal levels of anxiety/depression-like behaviors. We observe that the reduction in anxiety/depression-like phenotypes is associated with increased adult hippocampal neurogenesis. By improving the attachment of molecular motors to microtubules, huntingtin dephosphorylation increases axonal transport of BDNF, a crucial factor for hippocampal adult neurogenesis. Consequently, the huntingtin-mediated increased BDNF dynamics lead to an increased delivery and signaling of hippocampal BDNF. These results support the notion that huntingtin participates in anxiety and depression-like behavior and is thus relevant to the etiology of mood disorders and anxiety/depression in HD.
- [Show abstract] [Hide abstract]
ABSTRACT: Huntingtin (HTT), the protein mutated in Huntington's disease (HD), controls transport of the neurotrophin, brain-derived neurotrophic factor (BDNF), within corticostriatal neurons. Transport and delivery of BDNF to the striatum are reduced in disease, which contributes to striatal neuron degeneration. BDNF released by cortical neurons activates TrkB receptors at striatal dendrites to promote striatum survival. However, it remains to be determined whether transport of TrkB, the BDNF receptor, depends on HTT and whether such transport is altered in mutant situation. Here we show that TrkB binds to and colocalizes with HTT and dynein. Silencing HTT reduces vesicular transport of TrkB in striatal neurons. In HD, the polyQ expansion in HTT alters the binding of TrkB-containing vesicles to microtubules and reduces transport. Using a combination of microfluidic devices that isolate dendrites from cell bodies and BDNF coupled to quantum dots, we selectively analyzed TrkB retrograde transport in response to BDNF stimulation at dendrite terminals. We show that the retrograde transport of TrkB vesicles within striatal dendrites and the BDNF/TrkB-induced signaling through ERK phosphorylation and c-fos induction are decreased in neurons from an HD mouse model. Together, our findings demonstrate that HTT is a crucial regulator of TrkB trafficking. Transport defects in HD are not restricted to BDNF transport in cortical neurons but also affect trafficking of its ligand-bound receptor in the striatal neurons. This transport alteration may further impair BDNF-TrkB survival signaling within the corticostriatal connection that is most affected in HD.
- [Show abstract] [Hide abstract]
ABSTRACT: Huntington's disease (HD) is a devastating dominantly inherited neurodegenerative disorder caused by an abnormal polyglutamine expansion in the N-terminal part of the huntingtin (HTT) protein. HTT is a large scaffold protein that interacts with more than a hundred proteins and is probably involved in several cellular functions. The mutation is dominant, and is thought to confer new and toxic functions to the protein. However, there is emerging evidence that the mutation also alters HTT's normal functions. Therefore, HD models need to recapitulate this duality if they are to be relevant. Drosophila melanogaster is a useful in vivo model, widely used to study HD through the overexpression of full-length or N-terminal fragments of mutant human HTT. However, it is unclear whether Drosophila huntingtin (DmHTT) shares functions similar to the mammalian HTT. Here, we used various complementary approaches to analyze the function of DmHTT in fast axonal transport. We show that DmHTT interacts with the molecular motor dynein, associates with vesicles and co-sediments with microtubules. DmHTT co-localizes with Brain-derived neurotrophic factor (BDNF)-containing vesicles in rat cortical neurons and partially replaces mammalian HTT in a fast axonal transport assay. DmHTT-KO flies show a reduced fast axonal transport of synaptotagmin vesicles in motoneurons in vivo. These results suggest that the function of HTT in axonal transport is conserved between flies and mammals. Our study therefore validates Drosophila melanogaster as a model to study HTT function, and its dysfunction associated with HD.
- [Show abstract] [Hide abstract]
ABSTRACT: Fast axonal transport (FAT) requires consistent energy over long distances to fuel the molecular motors that transport vesicles. We demonstrate that glycolysis provides ATP for the FAT of vesicles. Although inhibiting ATP production from mitochondria did not affect vesicles motility, pharmacological or genetic inhibition of the glycolytic enzyme GAPDH reduced transport in cultured neurons and in Drosophila larvae. GAPDH localizes on vesicles via a huntingtin-dependent mechanism and is transported on fast-moving vesicles within axons. Purified motile vesicles showed GAPDH enzymatic activity and produced ATP. Finally, we show that vesicular GAPDH is necessary and sufficient to provide on-board energy for fast vesicular transport. Although detaching GAPDH from vesicles reduced transport, targeting GAPDH to vesicles was sufficient to promote FAT in GAPDH deficient neurons. This specifically localized glycolytic machinery may supply constant energy, independent of mitochondria, for the processive movement of vesicles over long distances in axons. PAPERFLICK:
Article: B14 Huntingtin mediates anxiety/depression-related behaviours in mouse through BDNF transport and hippocampal neurogenesis[Show abstract] [Hide abstract]
ABSTRACT: Huntington disease (HD) is associated with early psychiatric symptoms including anxiety and depression. Here, we demonstrate that wild-type huntingtin, the protein mutated in HD, modulates anxiety/depression-related behaviours through its phosphorylation at serines 1181 and 1201, two cyclin-dependent kinase 5 phosphorylation sites. Indeed, genetic phospho-ablation at serines 1181 and 1201 in mouse reduces basal levels of anxiety/depression-like behaviours in mouse. These behavioural effects directly depend on increased adult hippocampal neurogenesis. Indeed, focal dentate gyrus irradiation impaired neurogenesis but also anxiety/depression-related behaviour. Finally, the state of phosphorylation of huntingtin regulates neurogenesis as it influences brain-derived neurotrophic factor transport and subsequent signalling. DD and SH are both equal last authors.
- [Show abstract] [Hide abstract]
ABSTRACT: Cilia are unique cellular organelles found in nearly all cell types. In recent years, the importance of these organelles has been highlighted by the discovery that mutations in genes encoding proteins related to cilia biogenesis and function cause a class of complex syndromes termed ciliopathies. Emerging evidence suggests interactions among the various ciliopathy-associated proteins, but the precise mechanisms by which these interactions generate functional networks have remained elusive. In this issue of the JCI, Rachel and colleagues have now clearly linked two ciliopathy-associated proteins (CEP290 and MKKS). Surprisingly, the effects of a hypomorphic disease-causing Cep290 allele were rescued by loss of MKKS function, suggesting that it might be possible to treat some ciliopathies by fine-tuning interactions within the expanding ciliary network.
Top Journals
University of GrenobleGrenoble, Rhône-Alpes, France
Université Paris-Sud 11Orsay, Île-de-France, France
French Institute of Health and Medical ResearchLutetia Parisorum, Île-de-France, France
Institut CurieLutetia Parisorum, Île-de-France, France
French National Centre for Scientific ResearchLutetia Parisorum, Île-de-France, France
Yale University
New Haven, Connecticut, United States
- Department of Psychiatry
Boston Children's HospitalBoston, Massachusetts, United States
Institut de Génétique et de Biologie Moléculaire et CellulaireStrasburg, Alsace, France
Columbia University
New York City, NY, United States
- Center for Neurobiology and Behavior


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You're a mean one, Dr. Doof,
You really are a grump,
You're as pleasant as a pimple,
You're as smooth as a lump,
Dr. Doof,
You're an empty tuna can that's been thrown on the dump!
You're a monster, Dr. Doof,
You give us all a scare!
You're as kind and gentle
As a rabid polar bear,
Dr. Doof,
I wouldn't touch you with a 100-year-old dusty chair!
You're a vile one, Dr. Doof,
I'm really sure of that,
You have all the charming cuteness
Of a one-eyed vampire bat,
Dr. Doof,
Given the choice between the two of you, I'd take the one-eyed vampire bat!
You're a rotter, Dr. Doof,
Your plans are so monstrous,
You're wacky and you're crazy,
You're so mischievous,
Dr. Doof,
You're as kind-hearted as General Grievous!
You're a foul one, Dr. Doof,
You're a moldy old french fry,
You're wicked and you're schemeful
That we can't deny,
Dr. Doof,
Your mind is so ill and twisted that it makes you even more insane than good old Brundlefly!
You nauseate me, Dr. Doof,
You ain't no Santa Claus,
Your nose is sharp and pointy
Like Wolverine's claws,
Dr. Doof,
You're a plate of expired spaghetti sprinkled with grated moldy cheese and rotten tomato sauce!
I rewrote the song "You're a Mean One, Mr. Grinch" in Phineas and Ferb sytle.
It's not that I hate Dr. Doof, I just wanted to write a parody of the Grinch song!
It's not that I hate Dr. Doof, I just wanted to write a parody of the Grinch song!
I remember I told my "you're a mean one, Mrs. Grinch" because she wouldn't allow chips with my sandwich and she gave in. I regret it. Anyway, I hadn't read the song entirely the first time and I kinda rushed to read it all before making the comment I felt I should make (trying to be more courageous sorry that seems awkward)
Oh my ! Awesome !
hahaha love it
yush. but wait where's the one verse where it ends in "stink, stank, stunk"?
We know Dr. Doofenshmirtz is a mean one. After all, he once insulted a whale's macaroni and cheese recipe!
Hehehe...that's funny!
Quite hillarious! XD
And Doof's heart was two sizes too small....
And Doof's heart was two sizes too small....
Awesome job! This is my favorite Christmas song too!
hah one eyed vamp bat this made my day
this. made. my. day. im going to sing this all the time!
I sung that as the song sung to the Grinch in the movie How the Grinch Stole Christmas.
This made my day.~
This made my day.~
the dusty chair was a bit of a stretch but for the most part I liked it lol
du ba du bi du bi du ba du bi du ba du ba.......agents P.....
Hilarious. This made my day XD
(congrats on main page)
Win. xD
Win. xD
LOL! That's a really funny one right there, dude.
XD Nice
Love it!
HaHa! Nice <3


text:
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Book an announcement for publication online and in the next edition of the Lancashire Telegraph
Birthdays In Memoriam
William Ratcliffe
Published in the Lancashire Telegraph on 8 May 12
WILLIAM RATCLIFFE No birthday cards Bill, just happy memories. Love, Mabel.
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text:
The Right Prescription
Lost in the Senate
Dim Democrats and the "choice" Wyden plan.
Are all Democrats stupid or do you just have to be stupid to be a Democrat? I haven't figured that out yet.
The latest manifestation of the understanding-challenged comes with a New York Times op-ed last week by Oregon Democratic Senator Ron Wyden entitled: "Health Reform's Missing Ingredient." The missing ingredient, Wyden declares, is "choice."
"My guiding principle is, and always has been that consumers do better when there is a choice and competition," said the Senator, quoting no less an authority than President Barack Obama. Then quoting himself, he went on: "Empowering Americans to choose from a broad selection of health plans would turn the tables. Those insurers that charged affordable rates and provided good coverage would attract more customers."
Well, isn't that something? Newt Gingrich and the Republicans have been saying that for a decade, but let's take up the challenge. Why not free up the insurance market from burdensome state and federal regulations and let the companies sell whatever kinds of plan they want. Consumers could make their own choices and healthcare would be no more a "crisis" than cars or television sets.
It isn't so hard to imagine. Right here in New York I picked up a flyer in the supermarket the other day that offered the following health insurance policy:
• $5,000 per accident.
• $60,000 lifetime coverage for any of the following illness: cancer, cardiovascular, respiratory, blood and lymphoid, digestive, endocrine, musculoskelatal, nervous, skin, eyes, ears and nose diseases, etc,.
• 70 percent coverage, $100 deductible.
Not bad, eh? The cost -- $37.95 a month or $455 a year. The only catch is you have to buy it for your dog. If you're a human being, you have to pay at least $5,000 a year to buy basic protection.
Why? Because, like almost every other state, New York has regulated insurance to death. When you buy health insurance in New York, you can't just buy a simple policy. You have to accept coverage for mental health, psychiatry, psychologists, chiropractors, alcoholism, drug abuse, midwives, podiatrists, infertility clinics, occupational therapists, speech therapists, social workers and on and on. Other states mandate everything from massage therapists to acupuncturists to hair transplants. According to the Council on Affordable Health Insurance, there are close to 2,000 state mandates, which raise the price of insurance anywhere from 20 to 50 percent. And it's not consumers who are demanding this kind of coverage. It's the providers who lobby the legislatures to be included so they can get paid.
The result is insurance everywhere is overpriced. But that's just the beginning. As I outlined at length last week, the reason we have a "healthcare crisis" is precisely because so many people have managed to get out from under these state mandates while others remain stuck in them.
A long time ago, the Fortune 500 and their labor unions learned they could circumvent state regulations by setting up "self-insurance" pools for employees. Instead of buying insurance from insurance companies, the companies form their own pools and self-insure. All this is protected by the Federal Employee Retirement Income Security Act of 1974 (ERISA), which trumps state regulation. (States were granted regulation of the insurance industry by the McCarran-Ferguson Act of 1945, which has stifled competition and turned each state into a cartelized fiefdom.) Then, thanks to the IRS, these benefit plans are also tax-free. As a result, corporations and their employees loaded up on first-dollar, no-deductible coverage. Benefits were even extended to retirees so that -- as we just learned recently -- every Cadillac comes loaded with $3,000 in healthcare costs.
It was a great deal for those it benefited. In Patient Power, the best book I've ever read on the subject, John Goodman and Robert Musgrave speculated that it is precisely these "gold-plated" benefit plans that have driven up the costs of medical care, since the system is flooded with people spending other people's money.
The downside falls on those who are left out. If you aren't employed in a big company or the government, or if you're self-employed or work for a start-up or a company like Wal-Mart that's skimping every penny, or if you lose your job with the big company, then you're out of luck. Instead, you have to look for insurance in "the market," which consists of people like yourself plus those who are too sick to work or have been kicked out of their ERISA plans for running up too many bills. (ERISA plans are allowed to do this because they're not "insurance" but only "benefits.") Meanwhile, your state insurance commission, in classic stat-sponsored-monopoly fashion, has kept competitors out of the market at the behest of other competitors so your choices are limited. All you can buy is those Christmas-tree-laden mandated policies approved by the state legislation. You'll probably pay $5,000-10,000 a year for coverage that is costing an ERISA employee less than $1,000.
The "health insurance crisis," then, only exists for people outside ERISA's charmed circle. (Call up the ERISA Industry Committee -- 202-789-1400 -- if you don't believe any of this.) It's a phenomenon called "rent-seeking" where people use the government to institutionalize advantages at the expense of everybody else.
What could be done about it? There are plenty of proposals. The best is Health Savings Account (HSA), which extends the same tax-free benefits to everyone and allows people to put aside $3,000 of tax-free savings to pay their medical expenses. Combined with high-deductible insurance, this can work pretty well. Eight million people now have HSAs and it's climbing all the time (except the Democrats are always trying to abolish them). Then there are proposals to make it easier for small businesses or self-employed people to form their own self-insurance pools. Another idea would be to repeal McCarran-Ferguson and let people buy insurance across state lines. Or maybe we could just let everybody buy pet policies.
But the Obama Administration and Congressional Democrats are moving in a different direction. They want to pile on more mandates upon mandates, require small businesses to insure their employees, require everybody who isn't insured to buy insurance, fine everybody who doesn't, etc. etc. It's all in that 1,000-page bill. We'll find out after it's passed.
So now here comes Senator Wyden with his proposal for "choice." Let's hear what he has to say:
The various bills making their way through Congress would, as the president explained, provide some consumer choice by establishing large marketplaces where people could easily compare insurance plans and pick the ones that best suits their needs. Companies participating in these insurance exchanges would be required to offer coverage to anyone who wants to buy it, regardless of their age, gender or health status, and they would be barred from charging someone more for having a pre-existing condition.
The problem with these bills, however, is that they would not make the exchanges available to all Americans. Only very small companies and those individuals who can't get insurance outside of the exchange -- 25 million people -- would be allowed to shop there. This would leave more than 200 million Americans with no more options, private or public, than they have today. [Emphasis added.]
Did you get that? The problem, according to Senator Wyden, is that the 200 million people already in ERISA plans don't have enough choices. Here is his solution:
I am proposing… an amendment to the latest Senate health care bill…called Free Choice.… It would impose only one requirement on employers -- that they offer their employees a choice of at least two insurance plans, one of them a low-cost, high-value plan.… Ultimately, by empowering people to select the health insurance that makes the most sense for them and their family, we could end up with a system that works better for everyone.
So for Senator Wyden, the big problem isn't that 25 million people have been locked out of ERISA and forced to pay sky-high prices for meager coverage. The problem is that the 200 million Americans benefiting from ERISA only have one choice of gold-plated benefit plans instead of two. (Actually, many companies now offer a whole menu of options.) Besides that, it isn't fair that the 200 million people who are covered at work won't be able to shop in the dingy little market being rigged up for those who are left out. So we will mandate that employers offer a choice of two gold-plated plans instead of one.
How do people like this end up in public office? My only explanation is that Democrats live in such a tight, claustrophobic little circle of labor union politics, pressure groups and victim-mongering constituencies (who ever heard of an insurance company discriminated against customers "by gender"?) that they've lost all touch with the real world.
And these people are running the country.
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Blanton's Original70cl / 46.5%
- Single Barrel Kentucky Straight Bourbon Whiskey
- In Stock
- Next-day delivery available
Blanton's Original Reviews
9 Customer Reviews
good dram not as good as 4 roses s/b but far better than woodford reserve
If you see this bottle in your local store, grab it. I don''t think there is another bourbon that can out do Blanton and also has an amazing kick to it once time proceeds. There may not be another bottle within this price range that can give you a "bang for your buck". Makes you glad you picked up the bottle.
Just having a couple of shots for my cold
This bourbon is stunning ! Up there with the big boys in terms of flavour and complexity - one to sit back and sip and enjoy. As long as it is sipped it shouldn't require any assistance (water) I've just ordered two of the gold series as the reviews have it pitched up there with the best !!!!! Anything that comes close to pappy 20 yr old will be a main stay in my collection !!!
Blantons single barrel Bourbon Special Reserve. Received this as a 70th. Birthday present I must say that this is the finest liquid that has ever passed my lips.I do not feel that I have to describe it. Wonderful Blantons
This is real artisan single barrel whiskey. Smooth as you'd expect from a bourbon but fantastically woody and flavoursome. Some bourbons can rightly be accused of being one dimensional but not this! The stuff whiskey legends are made of.
Wow.. amazing service (as ever!) and what an amazing drink! Having sampled many a Single malt, bourbon and all the regular brands on offer in mainstream UK stores - this just about knocks everything out of the field. The instant, simmering heat on your lips completely hides the subtle, yet full spread of flavours that will engulf your taste-buds immediately after... just.. wow!
This is a bourbon with plenty to offer. Woody scents on the noseIt has a slightly spiritous burn to it but is, nonetheless, very easy to drink, offering hints of vanilla, candied fruit and chocolate as well as a long, spiced finish. For my money, not quite as good as Woodford Reserve, but close.
Tried this upon recommendation and was stunned at how immensely flavor-packed this bourbon is. Slightly hotter than the 12-yeaar Van Winkle Special Reserve, but still dangerously smooth and equally delicious.


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Best Pita Bread (2000)
Oriental Bakery and Grocery
Every morning Rafat Monem gets up at about 4:00 and heads to work, where he will bake more than 7000 individual loaves of pita bread. By early afternoon they will all be sold. Each loaf is an individual work of art, a light and airy source of comfort, whose gentle folds ply easily apart exposing a soft and inviting interior. Monem, the son of the store's owner, Okashah Monem, has been baking pita bread for seventeen years. What makes it special? "It's the ingredients we use," says Monem, a Palestinian who was born in Jerusalem. And what are those ingredients? "I can't tell you that," he laughs. "It's a secret."
Location Details
1760 SW 3rd Ave.
Miami FL 33129
Miami FL 33129
More Food & Drink Awards
Best HamburgerMorton's of Chicago
Best Key Lime PieEpicure Market
Best Caesar SaladCafe Ragazzi
Best TapasMacarena Tavern and Restaurant


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Protea Glen Manor offers: * Choice of 2 bedroom, 1 bathroom and 3 bedroom, 2 bathroom freestanding townhouses * Choice of style - Tuscan or Gable ...
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Brian was very calm and helped keep me calm. After 4.5 hours with the hearing officer (who was GREAT btw and incredibly thorough) I found out 1 wk later that I did in fact, WIN! I will be forever grateful to Brian for his work and especially for believing in me!
Thank you Mr. Stutheit!


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The Stealth Pro Wood Baseball Bat by Warstic® is part of our Pro Designer Series. This beautiful work of bat art features a Matte Black Wartip over a gloss Jet Black Finish with Metallic Gold engraving. Cut from Hand-Split billets. OK we admit this time, this one might actually be too pretty to play with in a game. But rest assured it's made with our highest grade Pro Sugar Maple or Birch so feel free;)
Also Available in Sr Youth & Youth Models
Only $89! Choose Birch Youth for your Wood Type >>
All Warstic® wood baseball bats come with FREE PLAYER NAME engraved on the barrel.
Delivery Time
Each Warstic® Wood Bat is made after the customer places the order. We do not stock bats. Bats are shipped between 7 - 12 business days depending on the size of the order. This practice is part of our commitment to the quality of our product.
Pro Prime Reserve™ Wood Baseball Bats by Warstic® are the hardest, toughest, highest performing professional grade wood bats we make.
Cut from our top 3% reserved selection of hand split Northern White Ash, Rock Hard Sugar Maple, or American Yellow Birch billets, Warstic® Pro Prime Reserve™ wood bats are individually Ink Dot tested to ensure they meet professional tangential slope of grain standards. This is big boy lumber. Period. No matter what level of play you are currently at, our Pro Prime Reserve™ Wood Bat Series gives you the option to swing the highest wood bat quality possible with the most customization options to suit your individual hitting style.
**Effective June 3rd, 2015**
All Pro Prime Reserve™ Warstic Wood Bats include a
30 day breakage Warranty!!!!
You must email pics of the bat and have proof of purchase receipt email. And you must ship the broken back to Warstic.
Choose from any turning style model in our catalog!
We have all the most popular and common models such as the 13, 72, 73, 110, 141, 159, 271, 243, 318, etc. Plus a large, ever-growing selection of our own custom models like the 19, 29, 49, 110N, 243X, and more.
Choose your Customization Options:
- Wood Type (Ash, Maple, Birch)
- Bat Model (Any in our Turning Style Catalog)
- Length (32"-35")
- Drop Weight -3, -2, -1, 0, +1, +2, +3
- Pro Approved Full Dip or Half Dip Stain Styles
- Pro Approved Warstic® Bat Stain Colors
- Pro Approved Handle Colors
- Pro Approved Engraving Color
Each Pro Prime Reserve™ Warstic® Wood Bat Includes:
- Free Player Name Engraving
- Premium Ivory Warstic Label on the back of bat
- Made USA Born on Date & Serial Number engraved on the handle
- Bat Specs engraved on the handle
- Our Trademarked Warstripe Warstic® Logo on the front
The Model No. 1 Vintage Style Ash Bat by Warstic® are made for Official Vintage League play or collecting. The Model No. 1 is patterned after turning styles of the 1860's. This heavy vintage bat is made from Hand-Split American White Ash features a thick handle with hardly any taper down from the barrel. Swings like a tree limb!
Wood: American White Ash
Lengths: 33" - 36"
Colors: Available in 5 color combos. See pics above.
Includes Free Warstic Bat Holster- Vintage Canvas
Delivery Time: Each Warstic® Wood Bat is made after the customer places and order. We do not stock bats. Bats are shipped between 7 - 12 business days depending on the size of the order. This practice is part of our commitment to the quality of our product.
The Blackhawk Pro Flame Treated Ash Baseball Bat by Warstic® is an American White Ash Baseball Bat made for serious game play. Cut from Hand-Split billets. Each bat is flame treated and then stained in Natural or Warrior Flame Stain. Blackhawks also feature a painted Black Longcoat. What's that? Well it means we paint the handle black but up a few inches past the Half Dip mark. Why? Because we wanted to. It's the best feeling Warstic yet. We can't put these down here at the shop. So we decide to make Blackhawks available in ALL of our Ash models.


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Pistachio Baked Salmon Recipe
4.5 5
Next time you're rushed by last-minute guests, try this fancy, flavorful salmon. With pistachios, brown sugar and dill, it's a guaranteed hit. —Cathy Hudak, Wadsworth, Ohio
- 6 salmon fillets (6 ounces each)
- 1 cup pistachios, chopped
- 1/2 cup packed brown sugar
- 3 tablespoons lemon juice
- 1 teaspoon dill weed
- 1 teaspoon pepper
- Preheat oven to 425°. Place salmon in a greased 13x9-in. baking dish. Combine remaining ingredients; spoon over salmon.
- Bake, uncovered, 12-15 minutes or until fish flakes easily with a fork. Yield: 6 servings.
Originally published as Pistachio Baked Salmon in Simple & Delicious May 2010, p17
Full-Bodied White Wine
Enjoy this recipe with a full-bodied white wine such as Chardonnay or Viognier.
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Cor, wish my Grannie's crib was as cool as this: slap bang on the beachfront, with an indoor pool, Jacuzzi and sauna, tennis courts and Costa Coffee on tap... Grannie's Heilan' Hame Holiday Park sits beside the powdery white sands of Embo Beach near the historic town of Dornoch, in prime position for a romp around the Scottish Highlands.
If you're bringing the family, rest assured that the chances of the little ones getting bored are slim to none. Aside from the pool- and beach-based shenanigans, there's mini ten-pin bowling, crazy golf, an amusement arcade, kids' clubs featuring Sid the hip-hopping seagull and Lizzie the lizard, plus a great adventure playground with a zipwire, swings and slides. Older children and teens can get stuck into making their own animated movies or hit the decks at a DJ workshop in the Freestyle club.
Grownups, meanwhile, will appreciate the smashing views across the Dornoch Firth - bottlenose dolphins and seals are regularly seen frolicking in the foam - plus the extensive facilities, which include a bar lounge and restaurant, evening entertainment, shop, launderette and more. Grannie would definitely approve...
Site type
Tourist board rating
Languages spoken
✓ English
Open from 20 Mar to 1 Nov
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text:
1 Corinthians 2:11New International Version (NIV)
11 For who knows a person's thoughts except their own spirit within them? In the same way no one knows the thoughts of God except the Spirit of God.
Cross references:
New International Version (NIV)
Holy Bible, New International Version®, NIV® Copyright ©1973, 1978, 1984, 2011 by Biblica, Inc.® Used by permission. All rights reserved worldwide.
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