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Body Art Paint from Tulip
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Body Art Paint Giveaway
Gifted by I Love to Create
Reviewed by Melissa Conner
Ever wondered how you would look with a rose or a sparrow tattooed on your shoulder? What about some stars on your wrist or a flower on your ankle? Forget those temporary rub-ons or your friend trying to draw it on you with markers…now there's a way to experiment with different shapes and colors before (or instead of!) going for something more permanent.
Body Art by Tulip is a great way to show your true colors, whether it be through tattoo art, supporting your favorite sports team, or topping off the ultimate zombie costume.
Start off your look with the Face and Body Paint Kit. This kit comes with 8 awesome colors, 2 brushes, and an instruction booklet on how to create the ultimate look. If you're looking for something a little more glitzy, try the Glitter Tattoo Kit, complete with 9 unique tattoo designs, 2 brushes, 6 colors of glitter paint, and more! Both the Face and Body Paint and the Glitter Tattoo paint last for up to 5 days…so you'll have lots of time to show off your artwork!
For those who want something more intricate and impressive, use Body Art's collection of nature stencils. This set comes with 25 designs, so you can be covered with flowers, butterflies, and leaves. These stencils are reusable, self-adhesive, and easy to cut, so you can use them to create designs anywhere you'd like!
If you are looking for something a little more permanent, try Body Art Spray Tattoo Ink & Stencil Kit. Art lasts for up to a week and looks so realistic! A variety of stencils are included so you can create a design that works for you!
To top off your look, use Body Art's cosmetic sponges to help blend and soften color. These are great for face painting, costume paint, or spreading paint over a large surface area. One package contains 6 sponges, each of which is reusable after a quick water bath.
So whether you're gearing up to finally go under the needle or you just want to add a little visual body flair, let Body Art by Tulip make its mark on you!
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patriciahobart 493 4265
Mar 09, 2012
I love this review of the Body Art by Tulip I have been thinking about doing body art designs for the fairs and art shows we have in our small town and want to offer something better that would be popular and last and this sounds like it would work great. I would love to try this product. Thanks for the great review.
patriciahobart 493 4265
Mar 09, 2012
I find the information on the body art paint from tulip very helpful I didn't know there were so many types of body art paint available and I have been looking for better ideas of how to do the body art paint and this gives me all the information and I would love to try these products. Thanks very much
onecraftymomma4lif e
Feb 04, 2012
I had a coupon for a craft store one day , and coulent find much i wanted and so i got a little 6 pc princess colors kit , pink, purple , green , blue , shimmy white , and i just can't rember the other color , and it came with 2 brushes , the brushes where of very good quailty , and I loved the colors and that they held up very well on my 6 year old , as long as she did not rub it hard it stayed on well and was very easy to paint with i really recomend this product for partys , halloween , or just for fun ...
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An NBC-Marist poll released on Friday showed Romney and Texas Rep. Ron Paul virtually tied for the lead among likely caucus-goers. It put former Pennsylvania Sen. Rick Santorum in third place and Perry in fourth. Gingrich was sliding to fifth from the lead he held only weeks ago. Minnesota Rep. Michele Bachmann fell to the bottom of the pack.
Perhaps more striking, Tea Party supporters are essentially divided among the field.
"This is not an election just to change presidents, it's an election to save the soul of America," Romney said in a speech at Kinzler Construction Co. in Ames. At Centro Inc., a plastics manufacturer in North Liberty, he emphasized that "government doesn't create jobs; the American people create jobs."
Romney's campaign in Iowa was solid, yet low-key, building upon a network of goodwill he earned in his second-place showing in 2008. His trusted consultant, Dave Kochel, and a few staffers grew that base into a grassroots organization that has kept voters engaged. In the final stretch, when demeanor counts, Romney is keeping his message positive.
Contrasting Romney's elegant rise is Bachmann's messy fall. She last enjoyed front-runner status the day before winning the nonbinding Ames straw poll, an August fundraiser for the state party. Perry overshadowed her win that day by announcing in North Carolina that he would run. This past week, Bachmann's Iowa campaign lost its chairman, Kent Sorenson, and political director, Wes Enos.
With voters, she compares herself to former British Prime Minister Margaret Thatcher. "I am the Iron Lady," she said at Legends, a family restaurant in Marshalltown.
That may well be, said Irv Vaske, 79, who sells "green" chemical products, but it's not likely to propel her first past the finish line -- especially since Bachmann spent more time with cable TV talk show interviews than voters who came to see her.
"I love her and her message, but I am going to go with a winner," Vaske said. He hasn't decided who that might be.
"Maybe Santorum," he said.
Santorum won over Mark McQueen, 48, a farmer who went to a Gingrich event in Carroll to "make sure Newt's my guy." He decided instead that Santorum "is the real deal."
Santorum, who completed a 99-county visit across Iowa, told the Trib that he's "connecting with voters on a level that none of the others are."
Yet, said Lara Brown, an expert on presidential elections at Villanova University, Republican voters in Iowa and elsewhere appear more interested in experience and electability than Santorum's ideological purity. They are gravitating to Romney, she said, because "voters are looking towards the steady candidate."
Famed Voting Rights/Anti-Poverty Activist Fannie Lou Hamer Called Abortion "Genocide" | Ryan Bomberger
Rush Limbaugh defends Rubio's debate answer: He's absolutely right that Obama knows what he's doing | Allahpundit
Time for Team Hillary to break out the gender card for young liberal women who prefer Sanders | Allahpundit

subset: commoncrawl


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Duke Back In Final Four After 66-52 Win Over GonzagaThe Blue Devils and their trio of freshmen starters are going to their 16th Final Four, a record-matching 12th for coach Mike Krzyzewski, after a 66-52 win Sunday in the South Regional over Gonzaga...
Sweet 16: Top Teams, Players And Games To Watch As March Madness ResumesOK, so maybe we won't get to see another celebratory fall by Georgia State's Ron Hunter, but the regional rounds of the NCAA Tournament are filled with some fantastic storylines.
Wichita State Shocks Mighty Ohio State in West Regional FinalMalcolm Armstead scored 14 points, Fred Van Vleet bounced in a big basket with 1 minute left, and ninth-seeded Wichita State earned its first trip to the Final Four since 1965 with a 70-66 victory over Ohio State on Saturday.
Five Things: FGCU First 15 Seed In Sweet 16 And Pac 12 Exceeds Its SeedsTo measure the unpredictability of this year's NCAA Tournament, consider two items that didn't make this column: Gonzaga, a 32-win team on a 15-game win streak, didn't survive the first weekend, and Harvard, a 14 seed, won its first ever Tournament game.
Rothstein: 10 Things I Learned During The First Weekend Of The NCAA TournamentFlorida Gulf Coast head coach Andy Enfield has won at life. There isn't much more to say than that.
Wichita St.'s 3-Pointers Boot No. 1 Gonzaga 76-70Gonzaga is out of the NCAA tournament thanks to Wichita State, a No. 9 seed that made five straight shots from behind the arc Saturday for a 76-70 victory that sent the West Region's top seed back home.
Prediction Machine: Pitt One Of The Favorites To Make Final FourPaul Bessire, better known by the name of his simulation program, "The Prediction Machine," joined The Fan Morning Show on Wednesday to offer the machine's advice for filling out brackets this year.
Five Things: Goodbye Big East, Buckeyes Win Big Ten, And West Coast BluesYesterday was a relatively drama-free Selection Sunday. Joe Lunardi was a perfect 68 for 68, as Middle Tennessee State, St. Mary's, Boise State, and La Salle claimed the final spots in the field. Louisville, Gonzaga, Kansas, and Indiana earned the top seeds.
Louisville Top Overall; Kansas, Indiana, Gonzaga Also No. 1 SeedsLouisville earned the top overall seed in the NCAA tournament Sunday, while Kansas, Indiana and Gonzaga also received No. 1s after a topsy-turvy regular season and another round of weekend upsets.
Rising Star: Gonzaga Junior Kelly OlynykGonzaga has a history of busting brackets but the Bulldogs now find themselves in the role of the hunted as Gonzaga became No. 1 in the AP poll for the first time in history.
Rothstein: Monday Morning College Hoops Notebook; New Mexico, UCLA & MoreIf there's a squad that should be rewarded outside the power six conferences with a No. 1 seed, it's New Mexico.
Rothstein Files: What To Watch This Weekend In College HoopsThis is a major opportunity for UCLA. The Bruins have yet to earn a marquee victory in the non-conference portion of their schedule and the Tigers will enter Pauley Pavilion as the seventh-ranked team in the country.


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Emma Booth (II)
Emma Booth was born in 1982 in Perth, Western Australia, Australia. She is an actress, known for Parker (2013), The Boys Are Back (2009) and Blood Creek (2009). See full bio »
Born:in Perth, Western Australia, Australia
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Will travel 50 miles from Fountain Inn
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Adopt This Pet: Fogerty
Fogerty is waiting for you at the Manchester Animal ShelterUPDATED 2:24 PM EDT Apr 02, 2014
Thank you for clicking on WMUR.com/pets.
The Manchester Animal Shelter has many animals waiting to be adopted.
Fogerty is described as awesome, sweet, wicked nice cat, and of course a couch potato. He is a male, neutered, long hair cat, whose age is estimated to be about seven years. Fogerty is great with all people, loves to just sit around, or play with his toys. He would get along with all ages, will be fine with other cats, but should be properly introduced to dogs.
Fogerty will require regular grooming, and don't forget that every outfit looks better with cat hair on it!
He is up to date on all his vaccines, and is micro-chipped.
For More Information contact the Friends of the Manchester Animal Shelter:
490 Dunbarton Road
Manchester, NH, 03105
Tel: 603-628-3544
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Cook In Colour Dome Bread Bin - Red
Fun and functional, this Dome Bread Bin from Cook In Colour is ideal for every day use. With a powder coated steel body, this bread bin features stainless steel hinges making it durable and tough. Complete with air vents to reverse to allow for air circulation which will keep your bread fresher for longer. Brighten up your kitchen with this practical and stylish accessory. - GG.
- Cook In Colour Dome Bread Bin
- Dimensions: L44 x W22 x H21cm
- Hand wash only
Product Details
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Please remember to add postal time (2-3 working days) to obtain a complete estimate of delivery to your door.
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You will receive an email to confirm when your item has been sent.
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Please allow 10 working days from dispatch of your order before notifying us of any late deliveries.
It may be advisable to check with your neighbours to see if a parcel has been left with them, check any outhouses you might have where it may be left if it cannot fit through your letterbox and contact your local sorting office to see if the item has been returned to the depot as undelivered and awaiting collection.
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Good price , cheaper than similar elsewhere . Modern and stylish
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beautiful! TaLins
Thank you very much Tummeow! Always appreciated!
Thank you very much Ally, greatly appreciated!
This is so beautiful TaLins! I LOVE it!
wow, so beatiful TaLins!!!! ♥
Thank you so much Megstuff, Corina and Andrea! Always and always appreciated!
Thank you Tracy, always appreciate you! Dont know how I missed you!
Beautiful tones ! :)
Your Grandaughter has talent like her Grandfather :) Love how she framed this and please tell her she has an admierer from Down- Under :)
Great work Talins!
Thank you very much Francoise, Tsuki, Christopher, and John, always appreciated!
Beautiful indeed, loving this site, thanks for all your help!
So lovely! Gorgeous tones!
amazing work TaLins!!
love the colors talins!
WWWonderful, TaLins! ☆ ☆ ☆ ☆ ☆! ;-)
Beautiful, looks wonderful on the products
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Wed, 30 June 2010 at 2:50 pm
Kristen Stewart: Today Show Chic!
Kristen Stewart drops by the Today Show in New York City on Tuesday (June 29).
The 20-year-old actress (in Helmut Lang) took time to sign autographs and meet the fans standing outside after chatting with Today's Matt Lauer and Meredith Vieira.
Earlier this week, Kristen visited The Late Show with David Letterman – check out her appearance and what she had to share about her pet wolf hybrid here!
Kristen Stewart on Today
Like Just Jared on Facebook
Credit: Jason Howard, Jose Perez; Photos: Bauergriffinonline, Splash News Online Posted to: Kristen Stewart


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Find a copy in the library
Finding libraries that hold this item...
|Document Type:
|All Authors / Contributors:
Leslie Brunetta; Catherine Lee Craig
|9780300149227 0300149220
|OCLC Number:
|A timeline of the spider fossil record. Fossils. Living fossils. Chance and change. Outward and upward. Triumph over thin air. Small changes, big benefits. Spinning, running, jumping, swimming. Going vertical. Links. Now you see it, now you don't. Beyond "perfect". Endless forms
|xiv, 229 p. : ill.
|Leslie Brunetta, Catherine L. Craig
Spiders, objects of eternal human fascination, are found in many places: on the ground, in the air, and even under water. Leslie Brunetta and Catherine Craig have teamed up to produce a substantive yet entertaining book for anyone who has ever wondered, as a spider rappelled out of reach on a line of silk, "How do they do that?" The orb web, that iconic wheel-shaped web most of us associate with spiders, contains at least four different silk proteins, each performing a different function and all meshing together to create a fly-catching machine that has amazed and inspired humans through the ages. Brunetta and Craig tell the intriguing story of how spiders evolved over 400 million years to add new silks and new uses for silk to their survival "toolkit" and, in the telling, take readers far beyond the orb. The authors describe the trials and triumphs of spiders as they use silk to negotiate an ever-changing environment, and they show how natural selection acts at the genetic level and as individuals struggle for survival.
User-contributed reviews


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|Reviews for This can't be happening
| TaurusGirl7 chapter 19 . 1/27/2006
update soon!
| Rose Jameson chapter 19 . 1/27/2006
| Addy Tyrant chapter 1 . 1/27/2006
I read your reviews, and I have to say...I disagree almost entirely with arachibutyrophobia.
it's in first person, so everything that is said is from the character's point of view. that includes all of her personal thoughts and descriptions. Haven't you had any outrageous thoughts that other people didn't agree with, or jumped to conclusions about a person based on their reputation, how they talked or dressed or what music they listened to? it's a humanistic habit and can't be helped. So I'd have to disagree if you insinuated that perhaps that should be changed. It gives the reader some insight into how the character thinks and , from her perspective, all of the popular girls are blonde bimbos, then it doesn't much matter how they really are-this is as if it's right from her brain, like her thoughts are real.
Did I make sense? hahaha, sorry to ramble. I just had to put in my two cents.
| kam-westlake chapter 19 . 1/27/2006
great story. cant wait to read the epilogue and see whats gonna happen to them after 5-6 yrs. update soon.
| Fades chapter 19 . 1/27/2006
Good story its sweet story congrats on the completion of the story it was fun to read oh and i recomend a song called for you i will by teddy Geiger it kinda fits with the story Update the epilouge soon
| Someday-I-will-Understand chapter 19 . 1/27/2006
aww cute. update soon )
| Lightning Storm chapter 19 . 1/27/2006
This story is one of the best. I can't wait to read how it ends. Update soon.
| Fraz chapter 18 . 1/21/2006
cool story. keep it up
| Ginne chapter 18 . 1/19/2006
Go you! This story is so amazing, i'm falling in love with Derek myself the man sounds so amazing and hot!
| SarahCLICK chapter 18 . 1/15/2006
wow, yes i suppose I did see it coming lol. You wrote it well though and he got her that dog How
| xJosiev88x chapter 18 . 1/14/2006
Aww he got her a puppy. How sweet?
| Neaera chapter 18 . 1/14/2006
I like his last line, about the relationship not being just sex. It shows a lot about his character. LOVE IT! KEEP IT UP HUNS!
| pottazcutey chapter 18 . 1/14/2006
O. So sweet. maybe not the sex part but it was so sweet. O. Anyway, great update (:
| TaurusGirl7 chapter 18 . 1/13/2006
update soon!
| dOrKy-GuRl03 chapter 18 . 1/13/2006
aw derek is so freaking sweet..wish have a boyfriend like that...i am so jealous of her...well keep updating girl...so loving it...can't wait the next chapter to post...well gotta go now...so peace out then...


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Pokemon Black Version
Question from CurseMark4Life
What is/are the best pokemon to use for HMs?
When I play pokemon my team usualy consists of 4-5 pokemon so the 1-2 other spots can be HM pokemon. I need some of the best choices fo pokemon that can learn from 2-4 HMs. The more the better. Right now I amonly using 4, but am cosidering a 5th member but still post as many options of pokemon that cna learn several HMs. Thanks in advance!
5 years ago
Top Voted Answer
Panpour and Golurk gets you everything but dig.
Panpour and Rufflet gets you everything but flash.
5 years ago
If you go to serebii(.)net and go to the black and white pokedex you can go through and find your on HM slaves
5 years ago
Yeah is you choice. I used yannapu, musharna, minezumi for 6 HM + flash, dig TM
5 years ago
Maybe this is a waste, but I still use Abagoura (the evolution of the blue turtle from the fossil) for strength, dive, and waterfall.
Abagoura is good with HM, because it can learn 4 of the 6 total HMs this time.
For fly, I have Kenhorou, and Surf Daikenki, both part of their useful moveset.
None of the HMs are tasteless this time to feel bad about wasting a moveslot with, like defog.
5 years ago
You can use Tsunbeaa (polar bear) and Washibon (eagle)
but you can only catch it after some long journey right?
5 years ago
Basculain for Dive, Waterfall,Cut,Surf
Swanna for Surf, Waterfall, Dive,Fly
Samurott for Surf, Cut, Strength, Dive, Waterfall
5 years ago
BASCULIN waterfall surf dive
TROPIUS fly cut strength flash
5 years ago
This question has been successfully answered and closed
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|Pokemon wanted genesect un nicknamed i have event arceus. Can someone trade me? I have other good pokemon too.
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|Hiun City Trades [In-Game], What Pokemon may I trade for what Pokemon?
|In Oplecuid city there is a person who asks for a pokemon that knows spark which pokemon is it?


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Villa Thalassa
from £92 /night help Price for guests, Nights approx:
from £92 /night help Price for guests, Nights approx:
Estimated nightly price based on a weekly stay. Contact the advertiser to confirm the total cost.
Chalet / 3 bedrooms / sleeps 6 Home 158494
Availability Your dates are available
Chalet / 3 bedrooms / sleeps 6
|Key Info
Villa Thalassa is situated in a prime front-line position, between Binibeca and Punta Prima and offers superb sea views. Binibeca with it's lovely sandy beach is 1km away and the commercial centre 600m. Villa Thalassa is a large airy property, built to a high standard and comfortably furnished. The living accommodation consists of, large lounge area with comfortable sofas and a fireplace, the lounge has Satellite TV and DVD player. The dining area is set out on the galleried landing, five steps above lounge area. The modern kitchen is very well equipped with all the necessary electrical household appliances and also has a utility room with wahing machine and tumble dryer. There are 3 bedrooms, one double bedroom and two twins bedrooms. The double bedroom has an en-suite bathroom and the two twin bedrooms share a shower room. There is another small room with WC and wash basin. The attic space has two sofas, which would perhaps suite teenage children. There is a private roof terrace, where one can sit and enjoy the sea views. Villa Thalass has a private pool of aprox. 9x4m with ample terraces both uncovered and covered and all the necessary poolside furniture. The airport, town and port of Mahon is around 15 minutes by car, the historic local town of Sant Lluis just 10 minutes, and a range of alternative beaches 5 - 10 minutes away
|Sleeps up to 6, 3 bedrooms
|3 bedrooms, 2 bathrooms of which 2 Family bathrooms
|Check in time:
|Check out time:
|Nearest beach
|Binibeca 700 m
|Car advised
|Nearest Amenities
|500 m
|Nearest travel links
|Nearest airport: Mahon 15 km, Nearest railway: N/A
|Family friendly
|Great for children of all ages
|No pets allowed, Yes, smoking allowed
Features and Facilities
|Internet access, DVD player, Sea view
|Private outdoor pool (unheated)
|TV, Video player, Satellite TV, Wi-Fi available
|Kettle, Toaster, Iron, Hair dryer
|Dishwasher, Cooker, Microwave, Fridge, Freezer, Washing machine
|Double Beds (1), Single Beds (4), Dining seats for 6, Lounge seats for 6
|Linen provided, Towels provided, High chair available
|Private outdoor pool (unheated), Balcony or terrace, Private garden, BBQ
|Parking, Not suitable for wheelchair users
The Balearic Islands region
The 2nd largest of the Balearics group Menorca is one of the most unspoiled islands of the Mediterranean. Its pristine coastline, with more than 80 beaches, the lovely rolling hills of the interior, and its temperate climate with summer temperatures rarely more than 28 degrees make the island a perfect holiday destination for those who want more than just sun and sea.
With pristine sea and nature (the island was declared a UNESCO Biosphere Reserve in 1993) Menorca is a perfect place for activity holidays, from sailing, sea kayaking and scuba diving, to walking and cycling . The newly reopened Camí de Cavalls is an ancient bridle path which mostly extends right around the island's coastline. A former coastguard and smugglers' path, the Cami is now a well signposted trail for walkers, horse riders and off road cyclists which is the perfect way to explore the hidden gems of the coast.
For nature lovers there are numerous protected areas, a marine reserve, and natural parks where many of the island's endemic flora and fauna can be seen. With a rich and varied birdlife, from the resident Egyptian vulture with its two metre wing span, to the osprey and booted eagle, plus numerous migrating visitors during the spring and autumn, Menorca is a Mecca for birdwatchers.
The island's cuisine, influenced by the many civilisations and colonial occupiers, from the Moors in the 8th century to the British in the 18th, is rich and varied.
Binibeca is one of Menorca's most atractive, relaxed and un spoilt resorts of the island. With no hotel constructions, only individual villas and few little apartment complex. It's beach is of soft white sand with cristal clear waters and nearby facilities. Ideal spot for families searching for a calm and safe holiday, away from massified resorts.
In fact, Binibeca is second home to a large number of holidaymakers who have decided to invest their moneis in a house or villa in this area. Any aged couples will also find this a perfect spot to experience Menorca at its best, with sailing and scubadiving schools based in it charming little port, few of the most popular bars (Paupa), restaurants (Sa Cova) and bistros (Na Rosa) will enhance your experience.
And many other highlights, such as its popular and charming fishing village, its rocky platforms, ideal for those searthing a little more intimacy when bathing, and much more.
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- 4 Years listed
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Calendar updated:15 Jun 2015
Based in Spain
- English
- Spanish


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Michelle Obama Wears a Dress by Jason Wu for Target
The dress is sold out online but still available in stores!By Ally Betker
The dress is sold out online but still available in stores!By Ally Betker
Plus, a new organization gives makeovers to seniors.
Plus, 43-year-old Helena Christensen in a bikini, Rachel Roy collaborates with Deepak Chopra, and more fashion news.
See what Yigal Azrouel, Altuzarra, Betsey Johnson, Band of Outsiders, and many more will send down their runways at New York Fashion Week.By Ally Betker
Shoes that are "strong and sexy."By Alex Rees
Plus, Emma Watson on her fashion problem, Kate Moss wears a turban, and more fashion news.
Sure beats the lingerie trend.By Amy Odell
Plus Anderson Cooper, Olivia Palermo, Andrea Riseborough, and more.By Bennett Marcus
Plus Kate Young, Jason Wu, Sylvana Ward, and more.By Summer Rej
Plus Olivia Wilde, Diane Von Furstenberg, Sarah Jessica Parker, and more.By Mara Siegler
Plus, Rooney Mara wore dark lipstick, and more beauty news.
Plus, a rabbi teaches Torah lessons through nail art.
Also, Rafael Nadal can strip and run simultaneously.
She's going to make gym outfits.By Charlotte Cowles
Their collaborative designs will reportedly be sold at Macy's next fall.By Charlotte Cowles
In other news, the sky is green!By Amy Odell
Plus: John Mayer pairs red wine with French fries, a Dom Scala sighting (!), and more, all in our weekly roundup of celebrity dining.By Alex Rees
Plus, Harriet Mays Powell launched a new fashion website.
She paired a silvery skirt with a bronze top.By Caitlin Petreycik
See runway photos, backstage, front row, and more!By Charlotte Cowles


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Cinnamon Trial-lIfestyle iNtervention Plus Water-soluble Cinnamon Extract On loweriNg Blood Glucose in Pre-diabetics (Cinnamon)
This study is currently recruiting participants. (see Contacts and Locations)
Verified February 2016 by Mike O'Callaghan Federal Hospital
Mike O'Callaghan Federal Hospital
Information provided by (Responsible Party):
Mike O'Callaghan Federal Hospital
ClinicalTrials.gov Identifier:
First received: February 18, 2011
Last updated: February 1, 2016
Last verified: February 2016
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
No Study Results Posted on ClinicalTrials.gov for this Study
|Study Status:
|This study is currently recruiting participants.
|Estimated Study Completion Date:
|July 2017
|Estimated Primary Completion Date:
|July 2017 (Final data collection date for primary outcome measure)


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Get Him to the Greek
Aaron Green (Jonah Hill) gets his chance to impress the big boss at the record company where he works when he agrees to persuade a famous British musician (Russell Brand) to perform in Los Angeles. But it seems impossible to get him to the Greek theater without also getting caught up in the star's world of sex, drugs and rock 'n' roll.
|MPAA Rating
|R for strong sexual content and drug use throughout, and pervasive language.
|Theatrical Release
|June 4, 2010
|Nicholas Stoller
|Jonah Hill, Russell Brand, Elisabeth Moss
|Run Time
|2010 Universal Studios
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text:
Fixed Value check using struts validator framework
Fixed Value check using struts validator framework Hi All,
can anyone tell me how to use struts validator framework for fixed value check.
eg. country='India';
Thanks in advance
Struts Validator Framework
project and it can be used with or without Struts. The
Validator framework comes... Struts Validator Framework
Framework. In this lesson you will learn how to use Struts Validator Framework
Struts Validator Framework
Struts Validator Framework What is Struts Validator Framework
Can anybody tell me how to use #parameters in struts 2 ?
Can anybody tell me how to use #parameters in struts 2 ? I have a login page, And by using struts.xml and #parameters I want to display error.../Login.jsp
Its urgent. Pl help me out
Tell me - Struts
Struts tutorial to learn from beginning Tell me, how can i learn the struts from beginning
does anybody could tell me who's the author - Struts
does anybody could tell me who's the author does anyone would tell me who's the author of Struts2 tutorial(http://www.roseindia.net/struts/struts2....
would you please tell how could I contact with the author ?
Struts Validator Framework - lab oriented lesson
( developeriq..Oct-2005...
framework.In this first part, a simple struts demo with non-framework based... of Validator framework, with
a lab-oriented lesson.
Since its introduction in 2001
Can anybody tell me how to resolve this issue?
Can anybody tell me how to resolve this issue? java.lang.Exception: Exception :
java.lang.Exception: Generic Errors = java.util.MissingResourceException: Can't find bundle for base name Connection, locale en_US
Tell me - Struts
Directory Structure for Struts Tell me the Directory Structure for Struts
Tell me - Struts
Directory Structure with example program Execution Tell me the Directory Structure with example program Execution
Struts Tutorial
, struts integration with other framework,
Struts Validator Framework.
What is Struts ?
Struts is an open source MVC based framework for developing web...,
internationalization, error handling, tiles layout etc. Struts framework is also
struts i have no any idea about struts.please tell me briefly about struts?**
Hi Friend,
You can learn struts from the given link:
Struts Tutorials
struts which is the best book to study struts on own?
please tell me
You can learn struts through the following books:
1)Programming Jakarta Struts By Chuck Cavaness
2)Professional Jakarta Struts By James Goodwill
Working with Eclipse IDE - Struts
to run my first struts program in eclipse 3.2.
what are the steps for running struts in eclipse .
Any body plz, tell me the setting environment of eclipse with struts.
Thanks in advance. Hi friend,
Read for more
use of Struts - Struts
use of Struts Hi,
can anybody tell me what is the importance of sturts? why we are using it?
Hitendra Hi,
I am sending... example.
Creating Custom Validators in STRUTS
Validator framework provides many
validation rules that can be used in the web... extend the validator
framework to develop your own validation rule.
The client... validation.xml and validator-rules.xml
to the directory where your struts-config.xml
Struts Tell me good struts manual
struts - Struts
files where i have to keep them,and war files.(tell me the list of jar&war files... for struts ,its well and good
by the way one point i should say you can put...struts Hi,
i want to develop a struts application,iam using eclipse
Struts - Struts
Struts hi
can anyone tell me how can i implement session tracking in struts?
please it,s urgent........... session tracking? you mean session management?
we can maintain using class HttpSession.
the code follows
Struts 1)in struts server side validations u are using programmatically validations and declarative validations? tell me which one is better ?
2) How to enable the validator plug-in file
Struts tag - Struts
Struts tag I am new to struts,
I have created a demo struts application in netbean,
Can any body please tell me what are the steps to add new tags to any jsp page
Code in IDE - Struts
Code in IDE In a project using struts how to get the contact no from user which should accept only '-' or '+' in IDE environment using struts... enters like for example(s.divya.kumar)It should show an error..pl do help me
What is struts - Struts
What is struts What is struts?Please tell me in simple language for what struts is used, it is necessary to learn it can we have some alternate for struts?What should we need to make a program in struts. Thanks
Struts 1 Tutorial and example programs
Introduction to Struts Validator Framework
Struts... Validator framework provides many
validation rules that can be used..., then you can extend the
validator framework to develop your own
struts how to handle exception handling in struts reatime projects?
can u plz send me one example how to deal with exception?
can u plz send me how to develop our own exception handling
Starting with struts - Struts
the display properly. Can anybody guide me through the steps for installing...Starting with struts Hi friends!
I'm new to RoseIndia & Struts. I downloaded struts 2 from Apache site, and unzipped its contents in my root folder
Struts - Struts
Struts Dear Sir , I m very new to struts how to make a program in struts and how to call it in action mapping to to froward another location. Acctually i m using netbeans ide when i select a new web application for struts its
Can anybody help me with this simple MySql code
Can anybody help me with this simple MySql code select c.countryid... cad 2013-03-16 18:26:31
can any one help me with the query because i want to select al of them but it should select for me only 1 duplicate countryid
Doubt in struts - Struts
Doubt in struts I am new to Struts, Can anybody say how to retrieve data from database and display it in jsp. Some said to use beans but i dont know how to do. Please help me in this regard. It will be helpful, if explained
Custom Validations - Struts
in struts 1.1.That is how can we plug in our own custom validations into Validator ?
Can anybody tell me how to do this with a sample example.
Thanks in advance
Vikrant Hi friend,
For more information on struts 1
struts
hi here is my code can you please help me to solve...;
<form-bean name
hashmap with struts and jsp - Struts
Can any one tell me the best approch for handling such situaltion...hashmap with struts and jsp i am trying to use hash map in struts.I am inserting on class object as value and string as key.This object is of class
Can i insert image into struts text field
Can i insert image into struts text field please tell me can i insert image into text field
Struts - Struts
Struts Hi All,
Can we have more than one struts-config.xml in a web-application?
If so can u explain me how with an example?
Thanks in Advance.. Yes we can have more than one struts config files..
Here we
Struts - Struts
Struts Is Action class is thread safe in struts? if yes, how it is thread safe? if no, how to make it thread safe? Please give me with good... safe. You can make it thread safe by using only local variables, not instance
Struts - Framework
to learn
and can u tell me clearly sir/madam? Hi
Its good... in any other framework or else before starting struts. you just need to have...Struts Good day to you Sir/madam,
How can i start
MVC - Struts
MVC Can any one help me in good design of an struts MVC....tell me any e-book so that i can download from site
DAO in Struts
DAO in Struts Can Roseindia provide a simple tutorial for implementation of
DAO with struts 1.2?
I a link already exits plz do tell me.
Thank you
validation - Struts
validation Hi Deepak can you please tell me about struts validations perticularly on server side such as how they work whats their role etc.?
thank you
Hi - Struts
please tell me its very urgent....I have a only oracle10g database please let me know it is possible to run struts using oracle10g....please reply me fast its...://www.roseindia.net/struts/
Thanks. Hi Soniya,
We can use oracle too in struts
exception - Struts
can anybody help me
Hi friend,
Here...exception Hi,
While try to upload the example given by you in struts I am getting the exception
javax.servlet.jsp.JspException: Cannot
Hii i want a JMS application can anybody help me
Hii i want a JMS application can anybody help me jms application
JSP - Struts
JSP Hi,
Can you please tell me how to load the values in selectbox which are stored in arraylist using struts-taglibs
Note:I am neither using... for ur response...but I want it in struts 1.X
struts and hibernate
end or other.
plz tell me...struts and hibernate i am new in advanced java technology
and i am getting confuse myself
struts tags are used in the front face of the page
multiple configurstion file in struts - Struts
multiple configurstion file in struts Hi,
Please tell me the solution.
I have three configuration file as 'struts-config.xml','struts-module.xml' and 'struts-comp.xml'.I have three jsp pages as 'index1.jsp','index2.jsp
Struts example - Struts
Struts example how to run the struts example Hi,
Do you know the structure of the struts?
If you use the Eclipse IDE,you can easily run the struts programs otherwise you use Tomcat.
Thanks Read
Struts - Framework
to learn
and can u tell me clearly sir/madam? Hi friend... project and is open source. Struts Framework is suited for the application...Struts Good day to you Sir/madam,
How can i start
configuration - Struts
configuration Can you please tell me the clear definition of Action class,ActionForm,Model in struts framework.
What we will write in each....
Action class:
An Action class in the struts application extends Struts
struts - Struts
the form tag...
but it is giving error..
can you please give me solution
Sturts - Struts
can provide credit card transaction logic or any money transfer logic.It is very important for me.Plz anybody send me the answer for this question.Thanks
websphere IDE and eclipse IDE
websphere IDE and eclipse IDE can we work struts framework in eclipse IDE. i am working in trial version of websphere studio application developer . if i work in eclipse all the features are available in eclipse
plese tell -Struts or Spring - Spring
plese tell -Struts or Spring Hello,
i want to study a framework... about spring.
which frameork i should do Struts or Spring and which version.
You need to study both struts and spring.
Please visit the following links
Cannot run Struts 2 on IntelliJ Project - Struts
Cannot run Struts 2 on IntelliJ Project I have been trying to run Struts 2 on IntelliJ IDEA for the past two weeks, can anyone help with basic... in NETBEANS IDE...
if u want i vl tell...u...
Library Management in Struts. - Struts
Library Management in Struts. Hi can you give me the application related to Library Management using Struts Or Jsp
struts - IDE Questions
Struts global forward example I need the global forward example in Struts
Struts Hi i am new to struts. I don't know how to create struts please in eclipse help me
Struts in struts I want two struts.xml files. Where u can specify that xml files location and which tag u specified
You can learn Struts at our Struts tutorials section.
Thanks...Struts How Struts is useful in application development? Where to learn Struts?
Struts is very useful in writing web
Validation - Struts
Validation How can i use validation framework i don't understand am having problem while implementing this, can anybody help me with example. Hi friend,
Phone validation using javaScript
doubt in struts - Struts
doubt in struts i don't understand the concept on Resource bundle in struts can u please help me out
struts application - Struts
struts login application form code Hi, As i'm new to struts can anyone send me the coding for developing a login form application which involves a database search like checking user name in database
struts Hi,... please help me out how to store image in database(mysql) using struts
struts please send me a program that clearly shows the use of struts with jsp
can easily learn the struts.
Thanks...struts how to start struts?
Hello Friend,
Please visit the following links:
book for struts 1.2.9 - Struts
book for struts 1.2.9 Can any body suggest me book for struts 1.2.9 ? because using net beans 6.1 and they provided struts 1.2.9 support for net beans 6.1
please suggest me book for same and link if u have so i can download
struts Hi,
1) can we write two controller classes in struts
Struts - Hibernate Integration
Struts - Hibernate Integration Hi,
I need to integrate the struts with hibernate..
can u pls tell me the process of configuring etc etc WITHOUT... link:
Struts Hibernate Integration
struts hi
i would like to have a ready example of struts using"action class,DAO,and services"
so please help me
please tell anybody how can i set a value in hiperlink for edit n delete link
please tell anybody how can i set a value in hiperlink for edit n delete link <logic:present name="allRecords">
<logic:notEmpty name="allRecords">
<logic:iterate id="user" name
Struts-problem With DispatchAction Class
: org/apache/struts/actions/DispatchAction
Can any one help me with this problem... DispatchAction..I'm using Eclipse ide..I hav configured struts-extras 1.3.10 jar but still...Struts-problem With DispatchAction Class hi this is Mahesh...i'm
java - Struts
java Can you pl. tell me what is the exact meaning of "DESIGN PATTERN". Where will use. What are the types in it? Hi friend,
Design..., and describes its solution to this problem in such a way that we can use this solution
struts we have the concept of jsp's and servlets right we can develop the web-pages each and everything then why what for struts inturdouced
struts Hi,
Here my quation is
can i have more than one validation-rules.xml files in a struts application
STRUTS 1)Have you used struts tag libraries in your application?
2)What are the various types of tag libraries in struts? Elaborate each of them?
3)How can you implement custom tag libraries in your application
please tell me
please tell me
<...:iterate>
how can i
for clarifying my doubts.this site help me a lot to learn more & more technologies like servlets, jsp,and struts.
i am doing one struts application where i... into the database could you please give me one example on this where i i have
Struts with Eclipse - IDE Questions
Struts with Eclipse How to develope struts application in Websphere Rational Application Developer 7.0? AT First Check Your Eclipse contain Plugins for Websphere 7.0 or not?
ifcontain go preference/eclipse
what is struts? - Struts
of the Struts framework is a flexible control layer based on standard technologies like Java... technologies to provide the Model and the View. For the Model, Struts can interact...what is struts? What is struts?????how it is used n what
struts i have one textbox for date field.when i selected date from datecalendar then the corresponding date will appear in textbox.i want code for this in struts.plz help me
Struts2 - Struts
Please can you tell me where i am doing wrong?
Please its urgent.... Please can i get some help?
Hi friend,
please, Can you send me code and explain in detail.
I am sending you a link. This link will help
Hello - Struts
Hello Hi,
Can u tell me what is hard code please send example of hard code... Hi Friend !
Hard coding refers to the software development practice of embedding input or configuration data directly
What are Struts?
What are Struts? What are Struts? Can anyone explain me what are the Struts framework and what are its uses?
Struts Database
Struts Database Can u show me 1 example of Struts jsp using oracle 10g as database! with struts config file
Struts database
Struts database Can u show me 1 example of Struts jsp using oracle 10g as database! with struts config file
Doubts on Struts 1.2 - Struts
Doubts on Struts 1.2 Hi,
I am working in Struts 1.2. My requirement is to display data in a multiple selected box from database in a JSP page.
Can anyone suggest me how to proceed...
Thanx in advance Hi friend
Mastering Struts - Struts
Mastering Struts Sir,
how can i master over struts. The theoritical part is very clear but the implementation part troubles me. What should I do? Until and unless i am guided over some struts Project i dnt think...its possible
Struts Example - Struts
Struts Example Hi Deepak
My name is dendi i want some good example in struts framework with sample code , hw to add and delete insert and update data into database by using sql, nw i am learning java struts u can help me
Struts I want to get the data from database into text box in a jsp page by using struts and javascript If I click on go button it will display all... the selected value into a variable. Plz help me out
Thanks in advance
Can you tell me how it worked?
Can you tell me how it worked? public class Ball
private static final int DIAMETER = 30;
int x = 0;
int y = 0;
int xa = 1;
int ya = 1;
private Game game;
public Ball(Game game) {
this.game= game;
void move
struts Hi,
i am writing a struts application
first of all i am takeing one registration form enter the data into fileld that
will be saved perfectly.
but now i can apply some validations to that entry details
but with out
Struts Why struts rather than other frame works?
Struts... and Hibernate to make the web based application secure and faster.You can also... by the application.
There are several advantages of Struts that makes it popular
struts---problem with DispatchAction
Can any one help me with this problem....
Thanks in Advance...struts---problem with DispatchAction hi this is Mahesh...i'm working with struts 1.3.10....I have created an application which uses DispatchAction
Struts Code - Struts
But it is not appending..
Can any one help me.
Thanks in Advance...Struts Code Hi
I executed "select * from example" query... using struts . I am placing two links Update and Delete beside each record .
Now I
Struts Tag Lib - Struts
Struts Tag Lib Hi
i am a beginner to struts. i dont have to understand the TagLib uri. Any body could you please give me some brief steps reg....
JSP Syntax
Examples in Struts :
The taglib
Hi.. - Struts
Hi Friends,
I am new in hibernate please tell me.....if i am using hibernet with struts any database pkg is required or not.....without any database package using maintain data in struts+hiebernet....please help
Java - Struts
Java Thank you so much , Tell me how to use "ejb in struts" for database acessing, i am not able to get the look up in struts by using ejb,
how...; Hai
You go through struts material in Roseindia Their have an example
Struts first example - Struts
Struts first example Hi!
I have field price.
I want to check require and input data type is int.
can you give me an example code... the version of struts is used struts1/struts 2.
Struts dispatch action - Struts
Struts dispatch action i am using dispatch action. i send... not contain handler parameter named 'parameter'
how can i overcome this problem please send me...
Thanks in advance
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text:
Hebrews 10:22King James Version (KJV)
22 Let us draw near with a true heart in full assurance of faith, having our hearts sprinkled from an evil conscience, and our bodies washed with pure water.
King James Version (KJV)
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text:
Dear Valued Customer,
GTA Trailer Rentals Inc. (GTA) and Markham Equipment Sales Ltd. (MES) have been sold to Trailer Wizards Ltd. The acquisition closed on June 1, 2015.
Frequently Asked Questions:
- I am a customer of GTA's. What does this mean for me?
- A phased transition plan has been put in place to ensure that there is no disruption to your business. We are working together to ensure that you continue to receive the highest level of service, safety, convenience and value as we begin to integrate and enhance your service experience.
- Trailer Wizards mission, vision, values and customer commitment are very much aligned with the culture at GTA/MES as well as the level of customer service you have come to expect. As part of Trailer Wizards, you will benefit from an expanded network as well as more services and efficiencies from a combined infrastructure.
- As a matter of formality and to ensure our database information is accurate, we kindly request that each GTA customer complete a Trailer Wizards Credit Application and Agreement form and submit it to Mariana Caraincica, Administrative Sales Support, at email@example.com. You may also fax it to 905.670.7312. We appreciate your co-operation in providing this information at your earliest convenience.
- Will I still be able to do business at the same locations?
- The locations in Gormley, Milton, and Cambridge, will continue to operate. As well, you will now have access to all locations where Trailer Wizards operates including British Columbia, the Prairies, Quebec, the Atlantic provinces and many locations in Ontario, providing Local Service… Nationwide!
- Who do I contact?
- Emergency: Please call the Trailer Wizard emergency line : 1 855 327 9377 (1 855 EASY ERS)
- Need a Trailer? Please call the phone number you currently use, or: 1 855-327-9757
- Complete listing of Ontario region sales and service contacts: Click Here.
- To locate a location near you: http://trailerwizards.com/en/contactus_customer_service_centres.php
- Who is trailer Wizards? Trailer Wizards is a Canadian family owned and run business that has been providing customer friendly trailer rental, leasing, sales, parts and service across the country for over 50 years. They were recently named winners of Canada's Best Managed Companies program. For more information please visit www.trailerwizards.com


text:
Kill and Run by CanisAlbusWatch
©2013-2016 CanisAlbus
A spontaneous gift for ~Wasabivallabi of her Saluki mix character Madame Nautinto. She's pretty much the drug lord of the Daisyland rpg.
your art's so classy ahah <33
this is gorgeous! What a lovely depiction of a lovely character! I really like the colors and the simple but suiting background!
You sure like making those fancy markings (the marking behind the character)
Ah I was totally going to do a picture on that song xD
Wonderful work too I really like her expression and the colors C:
I really love the thick black lines!
your style is absolutely amazing to me
i just don't get how you are so great at drawing
keep up the amazing work ;u;
luvely girl uwu
luved this~~
contrags ghoul sweetiee


text:
- Evaluations:
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Advertised: 21-11-07 | Closing Date: 12-1-08. A newly open Electronic Manufacturing company located in PEZA, Rosario, Cavite is urgently in need of: more
Advertised: 15-11-07 | Closing Date: 13-1-08. A newly open Electronic Manufacturing company located in PEZA, Rosario, Cavite is urgently in need of: more
Jobs in Wyntron, Inc.. Company description and vacancies. ... Wyntron, Inc. Address: Lot 9 Block 15 Phase 3 PEZA Rosario, Cavite, Philippines more
Job details: Purchasing Staff / Buyer. ... Wyntron, Inc. Purchasing Staff / Buyer : Male or Female, Single, 18-28 years old more
24 the nomad offices philippines inc. 25 v-tech trading logistics and services corp. 26 victory recovery and recycle technologies, inc. 27 wyntron inc. more
Wyntron, Inc. - Rosario, Cavite. It is unlawful to employ a person who does not have permission to live and work in the Philippines. Unless the advert states otherwise, please ensure ... more
WYNTRON: Furuhashi Knit Gloves: FORTUNECROSS: 19-Oct-09: Daiwa Seiko Philippines, Inc. Sekisui Jushi Phils. Inc. Sun Logistics Tech, Inc. Summit Strapping Corp. more
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hello :D Wyntron ako len :) magandang hapon din @all - eto nanaman ang oras.. ang oras ng paglisan.. hahaha.. babush babush.. o sha.. uwian time na :D bawal OT.. hahaha more
sir already send na po through you email add.. thanks.. Message appended on November 3, 2010 04:15PM thank you to ms jenny of wyntron for buying 12pcs of assorted VS product.. more


text:
Jesus Cures a Demon-Possessed Man—Matthew 8:28–34; Luke 8:26–39
1 They arrived in the territory of the Gerasenes on the other side of the Sea of Galilee. 2 As Jesus stepped out of the boat, a man came out of the tombs and met him. The man was controlled by an evil spirit 3 and lived among the tombs. No one could restrain him any longer, not even with a chain. 4 He had often been chained hand and foot. However, he snapped the chains off his hands and broke the chains from his feet. No one could control him. 5 Night and day he was among the tombs and on the mountainsides screaming and cutting himself with stones.
6 The man saw Jesus at a distance. So he ran ⌊to Jesus⌋, bowed down in front of him, 7 and shouted, "Why are you bothering me now, Jesus, Son of the Most High God? Swear to God that you won't torture me." 8 He shouted this because Jesus said, "You evil spirit, come out of the man."
9 Jesus asked him, "What is your name?"
He told Jesus, "My name is Legion [Six Thousand], because there are many of us." 10 He begged Jesus not to send them out of the territory.
11 A large herd of pigs was feeding on a mountainside nearby. 12 The demons begged him, "Send us into the pigs! Let us enter them!"
13 Jesus let them do this. The evil spirits came out of the man and went into the pigs. The herd of about two thousand pigs rushed down the cliff into the sea and drowned.
enclose words that the translation team supplied because the context contains meaning that is not explicitly stated in the original language.
Proper names or foreign words whose meaning is significant for understanding a particular Bible passage are translated in brackets following the name or phrase
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text:
Will Railton
Neknominate: should we oppose this lethal trend?14th Feb 2014 by Louee Dessent-Jackson, Will Railton
Following recent debate, Louee Dessent-Jackson and Will Railton discuss whether the 'NekNomination' phenomenon...
Are Oxford terms too short?19th Dec 2013 by Will Railton, Robert Walmsley
Michaelmas has come to an end so Will Railton puts it to Robert Walmsley that eight is enough.
Is Oxford doing enough to combat sexual violence?8th Nov 2013 by Will Railton, Robert Walmsley
Responding to Cherwell's latest investigation, Robert Walmsley and Will Railton debate whether Oxford is doing...
Is Oxford intimidating for freshers?12th Oct 2013 by Will Railton, Jack Davies
Will Railton and Jack Davies debate whether Oxford is more intimidating than the average university.
£26 million donation for graduate scholarships1st Mar 2012 by Will Railton
Widow of founder of Atlantic Records donates largest single sum of money to humanities students in Oxford's history
Oxford research into Libya and democracy23rd Feb 2012 by Will Railton
Research suggests that fewer than 1 in 3 Libyans would support a democratic regime
£90m needed to save the Humanities16th Feb 2012 by Will Railton
Oxford suffers from government cuts, asking for £90m to save 75 key government posts
Exeter Fellow writes a book on the origins of sex26th Jan 2012 by Will Railton
Dr. Faramerz Dabhoiwala's book due to be published on February 2nd
Oxford produces 'Super-tutors'19th Jan 2012 by Will Railton
Oxford graduates are among a new breed of tutors charging up to £1000 an hour to help schoolchildren with exams and...
Corpus Christi cans OxStu13th Jan 2012 by Will Railton
Corpus passes a motion to unsubscribe from the Oxford Student, following articles involving their members
Unions at his Beck-ham call31st Dec 2011 by Will Railton
The Oxford and Cambridge Unions are reportedly both vying to secure David Beckham as a speaker this term
Test errors impede History applications7th Dec 2011 by Will Railton
Prospective History students informed late about Oxford interviews, following a mix-up by HAT examiners at the...
Oxford places low down in drinking survey24th Nov 2011 by Will Railton
Oxford University ranks 59th out of 68 universities when it comes to weekly unit intake, as Oxford students drink...
Oxford tutors battle retirement18th Nov 2011 by Will Railton
University adopts policy to ensure dons employed past retirement age are suitable
Exam Regulations book under threat10th Nov 2011 by Will Railton
A motion has been passed by OUSU to discuss reducing numbers of the Exam Regulations printed
University applications down27th Oct 2011 by Will Railton
Despite a 9% fall nationwide, Oxford continues to receive a high number of applications
Protest against unpaid internships20th Oct 2011 by Will Railton
Campaigners from Intern Aware gathered on St Aldates to protest against unpaid internships
Break in at Hugh's17th Oct 2011 by Will Railton
Two laptops, a watch, a phone and a pencil sharpener amongst the stolen possessions


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State Health Departments Navigate ACA Enrollment Challenges While Strengthening Insurance Purchasing Infrastructure and Addressing Unmet Need Washington, DC – This week, the National Alliance of State and Territorial AIDS Directors (NASTAD) released new data [PDF 150 KB] emphasizing the essential role the Ryan White Program, specifically…
AIDS Drug Assistance Programs Support New ACA Coverage Options for Thousands of People Living with HIV
CDC Launches New Campaign – Start Talking. Stop HIV. – For Gay and Bisexual Men
Using Technology to Support HIV Testing and Medication Adherence: Lessons from Oregon
HIV Vaccine Awareness Day
Watch NIAID Director Anthony S. Fauci, M.D., discuss current HIV vaccine research approaches. Developing a safe and sufficiently effective HIV vaccine is essential if we are to achieve a timely and durable end to the global HIV/AIDS pandemic. The path…
Public Health Grand Rounds Focuses on PrEP for HIV Prevention
Ten Reasons to Address HIV/AIDS in Asian American and Pacific Islander Communities
Statement from Ambassador Deborah L. Birx, M.D., U.S. Global AIDS Coordinator, on PEPFAR's Approach to Achieving an AIDS-free Generation
President Obama and Secretary Kerry have committed PEPFAR to supporting countries in achieving an AIDS-free generation as a core pillar of the United States global health agenda. Together, we have made extraordinary progress toward this ambitious goal, saving millions of…


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House Party Stock PhotoColor Image,Confetti,Day,Deck,Horizontal,Indoors,London - England,Microphone,Music,No People,Outdoors,Party - Social Event,Photography,Turntable,UKPhotographer Lee PowersCollection: Taxi Lee PowersHouse Party.


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- 272Promote
Stationery Cards
bayside highby Pope Saint Victor
Set of folded stationery cards printed on bright white, smooth card stock to bring your personal artistic style to everyday correspondence. Each card is blank on the inside and includes a soft white, European fold envelope for mailing.
great job!
thanks eddie!
love this - the mountains are amazing! :)
love it!
great concept, mind boggling
love your work!
thanks everyone.
I love it!
pretty colour!
awsome POPE :)
thanks Kris! :)
Wow wow, love it!
@muxxi thanks! i love your work too.
So cool! And love those colors!
thanks Lisa! :)
Gorgeous piece ;)
Superb colors!
Nice! Very nice!
love it ♥
love the colour and texture!
I love it :)
this is amaaaaazing!
Everyone of these are amazing you are a really good artist i am memorised by your work!!
Love this
Guy on the left looks like he's about to break out into some capoeira moves :)
i loveeee this!
Love this!
Hi there, I wanted to let you know that I got this little guy for my iphone and it looks awesome! Thanks for creating such whimsical and humorous work that will make me happy every day to see it!
So good one !!
great! Love it
fantastic job
nice texture, nice color!
See More Comments


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Best Restaurant Row (2001)
Atlantic Avenue
Clematis Street is still out there trying, but it has nothing on Atlantic Avenue. This once-struggling thoroughfare virtually teems with eateries of every type, from haute Mexican to modern American to classic oyster bar. Interested in Italian? You got it. Crave a coffeehouse? That too. Perhaps even more significant are the extensions of the restaurant row. Now that it's practically filled up, side streets and off-the-beaten-track neighborhoods are benefiting from the spillover, and Japanese, Thai, and Middle-Eastern places are popping up all over. Note to Clematis: What is the holdup? You have the example, now follow it!
More Food & Drink Awards
Best MartiniCalifornia Café
Best Mediterranean RestaurantFinjan Bar & Grille
Best MargaritaMexican Cantina
Best BurritosTacos al Carbon


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Nut Job x Sparky Comic Part 3- C-Cotton!? by wezzie1Watch
©2013-2016 wezzie1
Oooh cotton, my favourite!
Cotton is quite a sweetheart, isn't she!? Even if she is kinda clueless sometimes...But adorable none the less!
Like what or who Nut job? Please tell me.
I found the cutest video on Youtube a little bit ago! And it's by the same guy who made Button Mash's adventures too! > www.youtube.com/watch?v=w1NEtn… Sorry I'm feeling kinda random tonight...
I've just got done listening to it! I loved it! That black stallion looked creepy...
It was kinda creepy... I thought it was adorable how Button kept trying to protect Sweetie Belle!
It was cute! It reminded me so much on how protective Sparky is over Dusk.
Bit pixelated but still worth reading.
*Sighs* Thank you very much for not being rude like everybody seems to be doing lately!
pff, i was a photo-manipulator back in the day, i understand having to deal with those kind of issues.
i also try to not be rude.
Well, my friend you do a great job of not being rude! I love it when people tell me what they think of my comics or other stuff, but I just hate it when they call it awful and just be plan rude!
we all start at the bottom, some forget where they came from, others embrace it. i have learned a lot since i first started doing images of any kind on the computer, but this doesn't make me look down my nose at those who are behind me.
i dunno where your artistic/photomanilpulative skills are, so i'm not saying you're worse than i.
I'm surprised by how well you chose your words. To be honest with I'm not even sure why people watch me anyways... This place is pretty much my other world. It's my escape from reality and no matter how rude people may be on here I still love it! And if I don't have anything nice or constructive to say about someones art I just won't comment, simple as that! Now if only some people would do that too....
my intricate choice of verbiage comes from 9 years of writing stories. i write, draw, and play video games. I too find this place as an escape. when video games become a bore and the world turns its nose up to my expressions, i turn to the blank canvas. weather that canvas has a cursor or a digital paint brush, i spill my soul onto it. if others like my work, so be it. if not, i didn't ask them to come and visit anyway.
everyone is allowed to state their opinion, and everyone is most certainly open to criticize my work, but some people have no care what words they use. no liabilities seems to lead to no remorse.
it's easy to say, but even i've become heated over what others say. however, while their verbiage you cannot control, your response can be. most trolls can be beaten by pure intellect, others are to stupid to realize they've been beaten; just ignore them.
i will say i'm glad that you do not let their idiocy and lack of care ruin this site for you. it would be immature of anyone to rage quit a website due to hecklers, at least without reporting it to the admins.
as for your work, you're as good as the experience you've accumulated. i.e.: practice practice practice lol.


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When sophistication is in order, you can`t do better than this chic Kathy Ireland 2BE256 evening gown! A beautifully embroidered band wraps around the waistline of its matching blazer, which sports slim, three-quarter-length sleeves. The sweetheart bodice segues smoothly into a floor-length skirt with a subtle sweep train.
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Antonio \L.A.\ Reid
L.A. Reid: Judging The X Factor Was the 'Worst Thing I've Ever Done'
Originally posted 06/08/2015 10:40AM
Two years after the cancellation of The X Factor, Epic Records CEO L.A. Reid is holding nothing back about his time spent on the judges' panel.
Though it was initially like a "vacation," as he told The Hollywood Reporter, his stint on the reality competition series ended up being "the worst thing I've ever done."
Beyoncé Attends Hillary Clinton Fundraiser
Originally posted 05/14/2015 05:30PM
As (Beyoncé has asked before: "Who runs the world?"
New Michael Jackson Album, Xscape, to Be Released in May
Originally posted 03/31/2014 04:45PM
The King of Pop lives on – Epic Records is releasing a new Michael Jackson album.
Tate Stevens's X Factor Win Proves Age Doesn't Matter, Says Simon Cowell
Originally posted 12/21/2012 02:00PM
While his girl group didn't win The X Factor, Simon Cowell thinks America got it right when viewers picked the show's oldest contestant, Tate Stevens, 37.
"We set out to do this show and take away as many rules as possible, partly to prove the point that you can sell records and be popular beyond the age of 29," Cowell said after the show's finale Thursday when Stevens, a married father of two, walked away with a $5 million recording deal.
"At my record label we don't have a sign on the door saying, 'If you're over 30 you can't sign here,' " he continued. "We don't run the business that way. This proves that there is a market for older people. I mean, look at Susan Boyle. I sold 30 million albums with Susan. So there's a market out there."
As for Simon's kind words, Stevens told PEOPLE, "[At the wrap party] Simon said some nice things which means a lot; he's the boss – and he seems to have a lot of confidence and in me going forward in my career."
The X Factor: Tate Stevens Wins the Show
Originally posted 12/20/2012 10:10PM
The X Factor ended on a particularly high note for one of the show's finalists Thursday night.
L.A. Reid's "Over 25" contestant Tate Stevens, 37, is the winner of season 2. He's a dad of two and a road worker from Missouri.
After performing live one last time the night before, Britney Spears's contestant Carly Rose Sonenclar and Simon Cowell's Fifth Harmony vied with Stevens for the $5 million recording contract.
The X Factor: Finalists Sing for Votes One Last Time
Originally posted 12/19/2012 10:40PM
Who's going to get a $5 million recording contract?
The X Factor's season 2 finale got underway Wednesday night with the finalists performing three songs each – including a duet with a music superstar.
Britney Spears's contestant, Carly Rose Sonenclar, has been a favorite, trading the No. 1 spot with her fellow finalist, L.A. Reid's country singer Tate Stevens, through out the competition.
Little Big Town, LeAnn Rimes to Duet with X Factor Finalists
Originally posted 12/19/2012 10:40AM
It's down to the wire for this season's The X Factor as teen sensation Carly Rose Sonenclar, country crooner Tate Stevens and girl group Fifth Harmony are set to square off in the finals this week doing duets.
Sonenclar, 13, is partnered with LeAnn Rimes; Stevens, 37, will shared the stage with the group Little Big Town; and Fifth Harmony will pair up with judge Demi Lovato as anticipation builds for a winner.
At a press conference Monday, The X Factor's creator Simon Cowell praised the finalists and predicted that anything can happen as the show prepares to wrap its season Thursday night on Fox.
The X Factor Reveals Season 2 Finalists
Originally posted 12/13/2012 09:10PM
Sparks will fly at the finale!
On Thursday, The X Factor revealed its top three acts, who will perform next week in the final night of competition – in hopes of taking home the $5 million recording contract.
Simon Cowell said it would take a miracle to get his girl group, Fifth Harmony, to the finale after they performed Shontelle's "Impossible" and Ellie Goulding's "Anything Could Happen" on Wednesday. Keep reading to find out if their dream came true ...
L.A. Reid: I'm Leaving The X Factor
Originally posted 12/13/2012 07:10PM
The latest season of The X Factor is down to the wire – but L.A. Reid is already looking ahead to next season. And he's not planning to come back.
"I have decided that I will not return to The X Factor next year," Reid, who is chairman and CEO of Epic Records, tells Access Hollywood. "I have a company to run that I've kind of neglected."
Of his decision to leave the singing competition, he says, "It saddens me a little bit, but only a little bit."
The X Factor: Who Stole the Show at the Semi-Finals?
Originally posted 12/13/2012 03:30PM
There may not be a front-runner following Wednesday's semi-finals on The X Factor, but there does seem to be a weakest link.
Most of the judges seemed down on girl group Fifth Harmony, whose rendition of Shontelle's "Impossible" left them wanting more, following a better performance of Ellie Goulding's "Anything Could Happen."
Britney Spears, Demi Lovato and L.A. Reid were all doubtful of Fifth Harmony's chances to be one of the three acts in the finals, with only Simon Cowell defending them, saying, "You've been one of the strongest acts tonight."
Not that the other performers were slouches.
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Camp counselor: Zach Hamill
Posted by Chris Forsberg, Boston.com Staff July 14, 2009 05:00 AM
In the second of a five-part series, the Globe's Fluto Shinzawa offers insight and analysis on Bruins forward Zach Hamill following the team's 2009 development camp.
What's your take on Hamill? Leave your thoughts in the comment section.
Previously reviewed campers:
News, analysis and commentary from the following Boston Globe writers:
- Amalie Benjamin, Globe Bruins reporter
- Fluto Shinzawa, Globe NHL reporter
get updates


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All temporary food service establishment permits - along with applicable fees - for the St. Patrick's Day celebration in Savannah must be turned in by 5 p.m. on Thursday, March 3.
The Coastal Health District of Georgia serves the counties of Bryan, Camden, Chatham, Effingham, Glynn, Liberty, Long & McIntosh
Welcome to the Liberty County Health Department, where our goal is to improve the health of our citizens by providing a range of public health services. We are proud to serve the citizens of Liberty County, including Fort Stewart, home of the 3rd Infantry Division. We have a dedicated Women, Infants, and Children (WIC) nutritional clinic on Fort Stewart and an independent, dedicated clinic to serve the needs of those living with HIV/AIDS in our county. We provide STD testing and STD Treatment. Our STD testing options include HIV testing, gonorrhea testing, chlamydia testing and syphilis testing. We have a long history of service to our community and continue that mission through projects such as BRAVE (Be Readily Available and Very Empathetic). BRAVE targets uninsured and underserved women in rural Liberty County in an effort to encourage them to seek appropriate breast care including monthly self breast exams, annual mammograms and necessary follow-up and diagnostic services. We also provide immunizations, pap smears and family planning services including birth control and pregnancy testing.
Liberty County Board of Health Meetings
Liberty County Board of Health meetings are held at 8:30 a.m. at the Liberty County Health Dept. located at 1113 E. Oglethorpe Hwy. in Hinesville.
The following meetings have been scheduled for 2016:
March 10
June 9
September 8
December 8
Hinesville Clinic
1113 East Oglethorpe Highway
P. O. Box 231
Hinesville, GA 31310
View Map
Phone: (912) 876-2173
Fax: (912) 368-8033
Hours of Operation:
Mon.-Fri. 8 a.m. – 5 p.m.
Ft. Stewart WIC Clinic
1183 W. Bultman Ave.
P. O. Box 1339
Hinesville, GA 31310
View Map
Phone: (912) 877-3330
Fax: (912) 876-3246
Hours of Operation:
Monday – Thursday:
7:15 a.m. – 4:30 p.m.
Friday 7 a.m. – 4 p.m.
Riceboro WIC Clinic
Head Start Center
Highway 119
Riceboro, GA 31323
View Map
Phone: (912) 884-3889
(only on 3rd Tuesday of each month.
At all other times, call 876-2173)
Hours of Operation:
Open only on the 3rd
Tuesday of each month
from 9 a.m. – 4:30 p.m.
Environmental Health Department
1113 East Oglethorpe Hwy.
P.O. Box 231
Hinesville, GA 31310
View Map
Phone: (912) 368-5520
Fax: (912) 368-5014
Hours of operation:
Mon.-Fri. 8 a.m. – 5 p.m.
Liberty CARE Center
1113 East Oglethorpe Hwy.
Hinesville, GA 31313
View Map
Phone: 912-876-5085
Toll Free: 877-221-6959


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Hey, welcome to my blog. Every blogger has a first blog entry, and this is mine. Some bloggers have a second blog entry, and I hope that includes me. We'll see...
I work at Microsoft, as a developer on the Visual C# IDE team. We do all kinds of cool stuff, like:
This is all in Visual Studio 2002. But I'm much more exited about all the awesome stuff that we're working on for the next version of Visual Studio (codename: Whidbey). I'll talk more about them in later entries.
I like to hang out on IRC, in Undernet's #C#. Drop by & say 'hi' sometime.


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iHerb Customer Reviews
Controlling leg swelling and circulation issues
12 people found the following review helpful
Posted by Reviewer1316951 on Mar 14, 2012
I had severely swollen ankles and legs and circulation issues and had to put my feet up regularly to alleviate it. I had throbbing and pain in my legs and exercise made it worse. After four days on these tablets, the problem had gone. I take two morning and night. The problem does recur if I stop but I am much better. I would highly recommend these to anyone with circulation issues. I have now been able to regularly exercise and am slowly losing weight. My husband also takes them and he has felt better and slept better since starting on them.
This product works
11 people found the following review helpful
Posted by Reviewer2525690 on May 15, 2012
An excellent product for managing and maintaining healthy blood flow throughout my body. The results that I feel from using nattokinaise indicate that this is working well for me....For anyone who is interested, those results include rock hard erections!
Good stuff
16 people found the following review helpful
Posted by Reviewer2905939 on Jul 27, 2011
I had a leg vein crisis and decided to try this stuff following the mostly great reviews. I went from painful hopping around with an ace bandage to an almost normal leg in about 2-3 weeks after taking 2 of these every night before bed. I'm convinced they contributed significantly to me not needing surgery. I would say that if you have painful legs, these are certainly worth a try.
3 people found the following review helpful
Posted by HealthlifeHK on Jul 23, 2013
爸爸因為有長期的糖料病和高血壓,我嘗試買了這個給他,沒有想到了,吃了1個月不到,身體各方面的感覺有明顯的改善,吃了3個月後,再去醫院做檢查,高血壓和血糖都正常了。 他現在還是堅持吃,我強烈推薦給大家買給自己的父母試試看。
15 people found the following review helpful
Posted by Reviewer1442423 on Jan 05, 2012
I had a stroke 12 years ago and they told me I would have to use aspirin and blood thinner for the rest of my life. I started using this a little after I had my stroke and I have had no blood clotting issues at all. I take 4 capsules per day. 2 capsules on an empty stomach between breakfast and lunch and 2 capsules right before bed.


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Are you William Klitz?Claim your profile
Publications (164)976.49 Total impact
- [Show abstract] [Hide abstract]
ABSTRACT: In order to explore the diversity and selective signatures of duplication and deletion human copy number variants (CNVs), we sequenced 236 individuals from 125 distinct human populations. We observed that duplications exhibit fundamentally different population genetic and selective signatures than deletions and are more likely to be stratified between human populations. Through reconstruction of the ancestral human genome, we identify megabases of DNA lost in different human lineages and pinpoint large duplications that introgressed from the extinct Denisova lineage now found at high frequency exclusively in Oceanic populations. We find that the proportion of CNV base pairs to single nucleotide variant base pairs is greater among non-Africans than it is among African populations, but we conclude that this difference is likely due to unique aspects of non-African population history as opposed to differences in CNV load. Copyright © 2015, American Association for the Advancement of Science.
Article: Whitey crumbles[Show abstract] [Hide abstract]
ABSTRACT: Despite scientific evidence to the contrary, cultural notions that incorrectly aggrandize genetic differences between ethnicities persist. New work on the genetic makeup of Europeans now shows even more definitively how false those notions are. Copyright © 2014 Elsevier Ltd. All rights reserved.
Article: Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: The Genes-environments & Admixture in Latino Americans study[Show abstract] [Hide abstract]
ABSTRACT: Asthma is a complex disease with both genetic and environmental causes. Genome-wide association studies of asthma have mostly involved European populations, and replication of positive associations has been inconsistent. We sought to identify asthma-associated genes in a large Latino population with genome-wide association analysis and admixture mapping. Latino children with asthma (n = 1893) and healthy control subjects (n = 1881) were recruited from 5 sites in the United States: Puerto Rico, New York, Chicago, Houston, and the San Francisco Bay Area. Subjects were genotyped on an Affymetrix World Array IV chip. We performed genome-wide association and admixture mapping to identify asthma-associated loci. We identified a significant association between ancestry and asthma at 6p21 (lowest P value: rs2523924, P < 5 × 10(-6)). This association replicates in a meta-analysis of the EVE Asthma Consortium (P = .01). Fine mapping of the region in this study and the EVE Asthma Consortium suggests an association between PSORS1C1 and asthma. We confirmed the strong allelic association between SNPs in the 17q21 region and asthma in Latinos (IKZF3, lowest P value: rs90792, odds ratio, 0.67; 95% CI, 0.61-0.75; P = 6 × 10(-13)) and replicated associations in several genes that had previously been associated with asthma in genome-wide association studies. Admixture mapping and genome-wide association are complementary techniques that provide evidence for multiple asthma-associated loci in Latinos. Admixture mapping identifies a novel locus on 6p21 that replicates in a meta-analysis of several Latino populations, whereas genome-wide association confirms the previously identified locus on 17q21.
- [Show abstract] [Hide abstract]
ABSTRACT: We have updated the catalogue of common and well-documented (CWD) human leukocyte antigen (HLA) alleles to reflect current understanding of the prevalence of specific allele sequences. The original CWD catalogue designated 721 alleles at the HLA-A, -B, -C, -DRB1, -DRB3/4/5, -DQA1, -DQB1, and -DPB1 loci in IMGT (IMmunoGeneTics)/HLA Database release 2.15.0 as being CWD. The updated CWD catalogue designates 1122 alleles at the HLA-A, -B, -C, -DRB1, -DRB3/4/5, -DQA1, -DQB1, -DPA1 and -DPB1 loci as being CWD, and represents 14.3% of the HLA alleles in IMGT/HLA Database release 3.9.0. In particular, we identified 415 of these alleles as being 'common' (having known frequencies) and 707 as being 'well-documented' on the basis of ~140,000 sequence-based typing observations and available HLA haplotype data. Using these allele prevalence data, we have also assigned CWD status to specific G and P designations. We identified 147/151 G groups and 290/415 P groups as being CWD. The CWD catalogue will be updated on a regular basis moving forward, and will incorporate changes to the IMGT/HLA Database as well as empirical data from the histocompatibility and immunogenetics community. This version 2.0.0 of the CWD catalogue is available online at cwd.immunogenomics.org, and will be integrated into the Allele Frequencies Net Database, the IMGT/HLA Database and National Marrow Donor Program's bioinformatics web pages.
Article: Erratum: Reconstructing Native American population history (Nature (2012) 488 (370-374) DOI:10.1038/nature11258)
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ABSTRACT: Highly polymorphic exons of the major histocompatibility complex (MHC, or HLA in humans) encode critical amino acids that bind foreign peptides. Recognition of the peptide-MHC complexes by T cells initiates the adaptive immune response. The particular structure of these exons facilitates gene conversion(GC) events, leading to the generation of new alleles. Estimates for allele creation and loss indicate that more than 10000 such alleles are circulating at low frequencies in human populations. Empirical sampling has affirmed this expectation. This suggests that the MHC loci have a system for moving valuable and often complex variants into adaptive service. Here, we argue that HLA loci carry many new mutant alleles prepared to assume epidemiologically meaningful roles when called on by selection provoked by exposure to new and evolving pathogens. Because new mutant alleles appear in a population at the lowest possible frequency (i.e., a single copy), they have typically been thought of as having little consequence. However, this large population of rare yet potentially valuable new alleles may contribute to pathogen defense.
- [Show abstract] [Hide abstract]
ABSTRACT: The peopling of the Americas has been the subject of extensive genetic, archaeological and linguistic research; however, central questions remain unresolved. One contentious issue is whether the settlement occurred by means of a single migration or multiple streams of migration from Siberia. The pattern of dispersals within the Americas is also poorly understood. To address these questions at a higher resolution than was previously possible, we assembled data from 52 Native American and 17 Siberian groups genotyped at 364,470 single nucleotide polymorphisms. Here we show that Native Americans descend from at least three streams of Asian gene flow. Most descend entirely from a single ancestral population that we call 'First American'. However, speakers of Eskimo-Aleut languages from the Arctic inherit almost half their ancestry from a second stream of Asian gene flow, and the Na-Dene-speaking Chipewyan from Canada inherit roughly one-tenth of their ancestry from a third stream. We show that the initial peopling followed a southward expansion facilitated by the coast, with sequential population splits and little gene flow after divergence, especially in South America. A major exception is in Chibchan speakers on both sides of the Panama isthmus, who have ancestry from both North and South America.
Article: Tracking human migrations by the analysis of the distribution of HLA alleles, lineages and haplotypes in closed and open populations[Show abstract] [Hide abstract]
ABSTRACT: The human leucocyte antigen (HLA) system shows extensive variation in the number and function of loci and the number of alleles present at any one locus. Allele distribution has been analysed in many populations through the course of several decades, and the implementation of molecular typing has significantly increased the level of diversity revealing that many serotypes have multiple functional variants. While the degree of diversity in many populations is equivalent and may result from functional polymorphism(s) in peptide presentation, homogeneous and heterogeneous populations present contrasting numbers of alleles and lineages at the loci with high-density expression products. In spite of these differences, the homozygosity levels are comparable in almost all of them. The balanced distribution of HLA alleles is consistent with overdominant selection. The genetic distances between outbred populations correlate with their geographical locations; the formal genetic distance measurements are larger than expected between inbred populations in the same region. The latter present many unique alleles grouped in a few lineages consistent with limited founder polymorphism in which any novel allele may have been positively selected to enlarge the communal peptide-binding repertoire of a given population. On the other hand, it has been observed that some alleles are found in multiple populations with distinctive haplotypic associations suggesting that convergent evolution events may have taken place as well. It appears that the HLA system has been under strong selection, probably owing to its fundamental role in varying immune responses. Therefore, allelic diversity in HLA should be analysed in conjunction with other genetic markers to accurately track the migrations of modern humans.
Article: Spectrum of HLA associations: The case of medically refractory pediatric acute lymphoblastic leukemia[Show abstract] [Hide abstract]
ABSTRACT: Although studies of HLA and disease now date back some 50 years, a principled understanding of that relationship has been slow to emerge. Here, we examine the associations of three HLA loci with medically refractory pediatric acute lymphoblastic leukemia (pALL) patients in a case–control study involving 2,438 cases and 41,750 controls. An analysis of alleles from the class I loci, HLA-A and HLA-B, and the class II locus DRB1 illuminates a spectrum of extremely significant allelic associations conferring both predisposition and protection. Genotypes constructed from predisposing, protective, and neutral allelic categories point to an additive mode of disease causation. For all three loci, genotypes homozygous for predisposing alleles are at highest disease risk while the favorable effect of homozygous protective genotypes is less striking. Analysis of A–B and B–DRB1 haplotypes reveals locus-specific differences in disease effects, while that all three loci influence pALL; the influence of HLA-B is greater than that of HLA-A, and the predisposing effect of DRB1 exceeds that of HLA-B. We propose that the continuum in disease susceptibility suggests a system in which many alleles take part in disease predisposition based on differences in binding affinity to one or a few peptides of exogenous origin. This work provides evidence that an immune response mediated by alleles from several HLA loci plays a critical role in the pathogenesis of pALL, adding to the numerous studies pointing to a role for an infectious origin in pALL. Electronic supplementary material The online version of this article (doi:10.1007/s00251-012-0605-5) contains supplementary material, which is available to authorized users.
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ABSTRACT: The Jewish diaspora can be viewed as a natural process in population dispersion and differentiation. We extend genetic studies on the Jewish diaspora to an analysis of human leukocyte antigen (HLA) haplotype distributions in the Jewish peoples, and show the value of this information for the design of Jewish marrow donor registries. HLA data from the Hadassah Bone Marrow Registry having parental country-of-origin information comprise samples of geographically discrete regions. We analyzed the HLA allele and haplotype frequencies for each national sample using population genetic and clustering methods. Population differentiation among diaspora populations was shown on the basis of HLA haplotype frequencies, including differences within the more recently diverged European groups. A method of haplotype and population clustering showed patterns of unique haplotype affinities associated with specific Jewish populations. The evidence showed that diaspora Jewish populations can be sorted into distinct clades of which the Ashkenazi are but one. Relationships among Jewish populations are interpretable in light of the historical record. We suggest that a major contributing factor to the genetic divergence between Jewish groups may have been admixture with local host populations, while, at the same time, threads of Eastern Mediterranean ancestry remain evident.
Article: Immunogenetics in the Holy Land
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ABSTRACT: We report an integrated analysis of nuclear (autosomal, X- and Y-chromosome) short tandem repeat (STR) data and mtDNA D-loop sequences obtained in the same set of 22 Native populations from across the Americas. A north to south gradient of decreasing population diversity was observed, in agreement with a settlement of the Americas from the extreme northwest of the continent. This correlation is stronger with "least cost distances," which consider the coasts as facilitators of migration. Continent-wide estimates of population structure are highest for the Y-chromosome and lowest for the autosomes, consistent with the effective size of the different marker systems examined. Population differentiation is highest in East South America and lowest in Meso America and the Andean region. Regional analyses suggest a deviation from mutation–drift equilibrium consistent with population expansion in Meso America and the Andes and population contraction in Northwest and East South America. These data hint at an early divergence of Andean and non-Andean South Americans and at a contrasting demographic history for populations from these regions.
Article: 145-P: Bootstrapping the Expectation-Maximization Algorithm to Calculate Haplotype Frequencies from Highly Ambiguous HLA Typing Data
Article: 148-P: Populations
Article: 144-P: HLA Associations With Birth Date and Age and Applications to Disease Association Studies
Article: 118-P: Modeling Effective Patient-Donor Matching for Hematopoietic Transplantation in United States Populations
Article: 156-P: Reference High-Resolution HLA Haplotype Frequencies for 21 US Populations Derived from the Entire DNA-Typed Donor Registry
Article: 112-P: Simulation of Cord Blood Unit (CBU) Inventories Shows Lower Match Rates Than Population-Based Models Because of Depletion of High Total Nucleated Cell Count (TNC) Units With Common HLA
Top Journals
- Human Immunology (55)
- The American Journal of Human Genetics (14)
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University of California, Berkeley
Berkeley, California, United States
- • School of Public Health
- • Department of Integrative Biology
United States Institute of PeaceWashington, Washington, D.C., United States
Hadassah Medical CenterYerushalayim, Jerusalem, Israel
Children's Hospital & Research Center OaklandOakland, California, United States
Children's Hospital Oakland Research InstituteOakland, California, United States
Basel, BS, Switzerland
- Department of Human Genetics
University of Texas Southwestern Medical Center
Dallas, Texas, United States
- Department of Pediatrics
NCI-FrederickФредерик, Maryland, United States
University of California, Los Angeles
Los Ángeles, California, United States
- Department of Human Genetics


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