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April 9, 2014
Rice University student-athletes celebrated a successful year on Wednesday night at the annual Night of the Owl event, presented by the "R" Association. Women's tennis senior Dominique Harmath and baseball's Andrew Murphy and claimed the top honors bestowed on Rice University scholar-athletes.
A Toronto, Ontario native, Harmath received the 39th Joyce Pounds Hardy Award, which honors long-time Rice supporter Joyce Pounds Hardy and is presented to the top overall female student-athlete for her efforts in athletics, in the classroom and in the community. The two-time first team all-Conference USA team member in singles helped the Owls claim the 2013 league title and advance to the NCAA Tournament each of the past two seasons. She also represented Canada last summer at the World University Games in Russia. Harmath is a three-time C-USA Commissioner's Honor Roll member and was named to the C-USA Academic All-Conference team last season.
Murphy, a catcher for the Owls took home the 2014 Bob Quin Award, given annually to Rice Athletics' most outstanding all-around senior male athlete. The award honors Quin, a well-respected Rice student-athlete who passed away during an Atlantic voyage in 1930. The Shreveport, La. native is a reserve catcher that has played a crucial role in preparing one of the top pitching staffs in the nation. Murphy has helped the Owls claim Conference USA titles and NCAA Tournament berths in each of his three full seasons. He was honored as Rice's C-USA Spirit of Service Award winner in 2012 for completing more than 100 service hours in that academic year alone. Murphy is also a fixture on the C-USA Commissioner's Honor Roll and was the program's 2013 Rice Scholar Athlete.
Also recognized during Night of the Owl were most valuable players for each sport along with other end-of-the-year awards. The celebration included the presentation of Rice Athletics' highest academic awards, the OJ Brigance Courage Award, the Carl Isgren Iron Owl Award winners along with Spirit and Community Service awards.
Men's basketball senior Bahrom Firozgary earned the "R" Association's J. Fred Duckett Postgraduate Scholarship, while Harmath was named the "R" Association Margie E. Sass Postgraduate recipient.
Firozgary walked onto the Owls basketball team as a junior and saw action in 45 games over two seasons, including three starts. The 2013-14 Rice Scholar Athlete for men's basketball was one of two Owls and just four Conference USA players to be named to the NABC Honors Court for academic excellence in 2012-13.
Among the sport MVPs, Clayton Chaney (men's track and field), Casey Clark (swimming) and Jessica Kuster (women's basketball) were repeat winners.
Below is a complete list of award winners.
Night of the Owl Award Recipients
Joyce Pounds Hardy Award – Dominique Harmath (tennis)
Bob Quin Award – Andrew Murphy (baseball)
"R" Association Margie Sass Postgraduate Scholarship – Dominique Harmath (tennis)
"R" Association J. Fred Duckett Postgraduate Scholarship – Bahrom Firozgary (basketball)
Carl Isgren Iron Owl Awards – Darik Dillard (football), Zech Lemond (baseball), Lilly Marrow (swimming)
O.J. Brigance Courage Award – Michael Kutzler (football)
SAAC Coach of the Year – Jim Bevan (women's cross country and track & field)
Freshman of the Year – Cali Roper (women's cross country)
Sport MVP Awards
Baseball - Dell Morgan Award – Zech Lemond
Men's Basketball - Billy Wohn Award – Austin Ramljak
Women's Basketball - Gene Hackerman Award - Jessica Kuster
Men's Cross Country - Jeff Wells Award – William Firth
Women's Cross Country - Mikki Hebl Award – Cali Roper
Golf - Vic Cameron Award – Kevin Reilly
Women's Soccer – Lauren Hughes
Swimming - Catherine Hannah Award – Casey Clark
Women's Tennis - Kay Pearson Keating Award – Katie Gater
Men's Tennis - Sammy Giammalva Award – Jonathan Chang
Men's Track and Field - Fred Hansen/Dave Roberts Award - Clayton Chaney
Women's Track and Field - Eva Jean Lee Award – Heather Olson
Volleyball - Hally Beth Poindexter Award – Kimberly Vaio
Football's George Martin Award winner will be announced at Sunday's team banquet
More Headlines
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Johnson Ties for 23rd at HBU Husky Intercollegiate
09/22/2015 - Senior Trey Johnson tied for 23rd-place at the HBU Husky Intercollegiate, played at the par-71, 6,931-yard Quail Valley Golf Club.
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The talk of new gun control measures that has followed Friday's mass shooting in a Newtown, Conn., elementary school has gun owners rushing to the nearest store and picking up new weapons, according to gun store owners and state police background check information.
In the time since he took office, gun sales have soared. The government doesn't track individual sales. But the FBI criminal background check required to purchase a gun is considered a reasonable proxy, and these have hit record numbers each year Obama has been in office. This year, they're on track to surpass 15 million for the first time.
Dealers and analysts have several theories. One is that hardcore gun enthusiasts fear the lousy economy will set off a crime wave. Another is that political upheaval over the federal debt may lead to riots like those in Greece and London. Still another popular, if paranoid, belief that's taken hold among gun-rights advocates: that Obama is waiting until he is reelected to separate Americans from their firearms, prompting worried gun owners to stock up in anticipation.

subset: commoncrawl


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Grim Executioner 2 by Dragoroth-stockWatch
©2012-2016 Dragoroth-stock
Please see my main page for rules. Thanks!
Daily DeviationGiven 2012-10-24
[Stock and Resources] Suggester says, "The costume and accessories are simply epic and the blurred background means that extracting the model won't make you lose your mind... just maybe your head! ;)" Grim Executioner 2 by ~Dragoroth-stock ( Suggested by DamselStock and Featured by PirateLotus-Stock )
Where can I get this armor? I'd love to recreate this costume if possible.
I keep looking at this guy. Really well done. I'd love for the blur to be in-camera, but the post-production blur is neat as well.
damn good!!
haaaa denn kensch
From the thumbnail I thought it was a screenshot from a video game!
A bardiche to cut someone's head off? I am somewhat unimpressed at his choice of tools.
Pardon my French, but that is dead-sexy.
congrats on the dd he looks a little like ezio auditore from asassins creed
Very awesome ]: )
Very reminiscent of the Nico's Dreadweave mod(s?) for Oblivion. Cool.
Oh shit.
n1 you deserve for dd
Nice man, this really does deserve that daily deviation award.
A Daily Deviation is just a 24 hour feature, not an award But it was awesome, so I suggested it to ^PirateLotus-Stock who must've agreed with me
Well, it is a 24-hour feature, but it is known as a Daily Deviation Award [daily feature], just like the Deviousness Award [monthly feature] and the Bolt Award [yearly feature].
No, it is only known as a feature. People thinking it is an award are very much mistaken. It is a 24 hour site-wide feature. That is all, nothing more. Talk to any of the admins, or the CV's who post the DD features, and they will tell you the same thing.
The title is Daily Deviation. It is not Daily Deviation Award. It is different from the Deviousness Award.
Please refer to FAQ 61 for further clarification as it was written by the admins.
FAQ #61: What is a Daily Deviation?
The title is Daily Deviation. It is not Daily Deviation Award. It is different from the Deviousness Award.
Please refer to FAQ 61 for further clarification as it was written by the admins.
FAQ #61: What is a Daily Deviation?
It seems I've been mistaken. Thanks for the clarification (I've been calling it an Award for three years ).
Wonderful work!!!
The garb is gorgeous. He definitely strikes me as a dark convoy.
Without this excessive blurring, you would have seen the ugliest fence ever in the background Wouldn't really fit the atmosphere I thought...
Oh man. I love this! The blurring is not only handy for extracting, it just makes the photograph seem so much cooler too


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Perhaps, get to see a movie full 1 time in 4.Yeah, and youtube works? Finally!
Installed Beta1 + rp10.dll beta2 --> All OK
I do not know if it depends on algorithm is too aggressive but I upload the video jerky and then to 60% crashes.
It seems that the CPU is working very slow because the PC will not change until the page or I close Internet Explorer.
However I will do other tests.


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Please enter a valid mileage
Curious about the newer model? Check out the 2017 Audi Q7
By KBB.com Editors
Now in its third year of production, the 2010 Audi Q7 quattro has proven a triumph of technology, elegance, performance and quality. The Premium Plus version wraps around seven passengers in classy comfort and safety, offering innovative features to help you park easily, drive smoothly and enjoy a versatile lifestyle. With all the hallmarks of Audi's heritage, the Q7 does not disappoint, and handling and interior amenities compare with any luxury sedan. Finally, the quattro all-wheel-drive system provides exceptional slick-surface traction and security.
If you require seating for seven but dread the thought of trying to park a full-size SUV, you'll love the Q7. The Q7 's available rearview camera guides you into place with an onscreen view. Hauling people? Try the 28 different seating configurations. Cargo? Maximum trunk capacity is a mammoth 72 cubic feet.
You may not like the Q7 if adults must use the third row. They could have trouble squeezing in and out, but children and most packages fit easily. Speed demons may find the gasoline V6 version a bit underpowered.
The Q7 receives a slight exterior freshening, with a new grille, lights, mirrors and lower panels. LED daytime running lamps are added to V8 models, while all trims receive LED tail lamps and turn signals. The Luxury Package gains ventilated front seats.
Driving Impressions The heft and solid feel of the 2010 Audi Q7 tooling along at highway speeds delivers a sense of sure-footedness and stability. The cruise control is easy to use and...the adaptive air suspension's three choices – Dynamic for sporty driving, Automatic, and Comfort – cover every imaginable preference or requirement. In the off-road mode, the 8.1 inches of ground clearance works well over rocks and deep ruts, although severe washboard trails can generate some expected harshness. Then, back on-road, the suspension system automatically lowers the Q7 for higher-speed stability. While the Q7 is a fairly heavy vehicle and has a less-than-tight turning circle, the steering is precise and road noise is minimal. The seats are high, wide and supportive, the airy sunroof lets in lots of light and, with every function and feature at your fingertips, driving the Q7 compares very well to the top players in its field.
Adaptive Cruise Control
This system controls speed and following distance in traffic. The driver chooses his driving mode, which automatically determines the following interval from the vehicle in front.
Parking System
This system consists of a rearview camera and audio alert to aid in parking. An image of the rear bumper, with color-keyed assistance, appears on the monitor as the Q7 is backed into a parking space. Blue areas show if the space is large enough; orange lines guide the driver for parallel or angle parking.
The interior, like all Audis, is second to none. The 2010 Audi Q7 is trimmed with luxury woods, aluminum inlays and stitched leather everywhere, including the heatable steering wheel. The cockpit is based on the A6 and every ergonomically-designed button, knob and switch is within easy reach, whether on the steering wheel, the dash or next to the shift lever on the center console. There are ten cupholders, a cooled glovebox, the driver's seat and steering column are both height-adjustable and both front seats have lumbar support. The middle seat in the second-row bench flips down to form a mini-table, and single-pull levers allow folding the seats flat. As would be expected, there is a full complement of frontal and side airbags. The cargo compartment includes tie-downs, cargo nets, a retractable cover, partitions, telescoping racks, a ski sack and a protective liner.Exterior
The 2010 Audi Q7's exterior is sleek, striking and sporty, with a bold rectangular grille, high beltline, narrow side windows and a coupe-like roofline capped by a rack. The front overhang is comparatively short but in perfect proportion to the intent of the sporty design. A long wheelbase provides the Q7 with a self-possessed elegance. Headlamps, door handles and arched fenders fuse into a seamless, graceful unit. Sporty styling keeps this large SUV from the behemoth category and sets it apart as a well-appointed vehicle, for either the Ritz or river-side camping. The raked windshield, a small rear roof spoiler that houses the third rear light and a three-panel sunroof, complete with shade, are well-integrated. A wrap-around 45.7-inch wide tailgate lifts on hydraulic pistons and can be programmed to rise to the height of your choice. Heatable, fold-flat sideview mirrors are massive, and settings are saved in memory.
The Q7 3.6 features Premium Sound audio, quattro all-wheel drive, side mirrors with LED turn signals, dual-zone automatic climate control, power and heated front seats in leather, power liftgate and 18-inch alloy wheels. The Premium Plus adds xenon headlamps with LED running lamps, panoramic sunroof, navigation with rear parking camera and ultrasonic rear park assist, Bose Surround Sound audio and power folding side mirrors. Standard safety equipment includes front side and side-curtain airbags, electronic traction and stability control and anti-lock brakes (ABS).
A worthwhile extra is the adaptive air suspension system with adjustable ride height and roll stabilization. Also available are rear side-impact airbags and an adaptive cruise control that controls speed and following distance in traffic. Audi's side assist utilizes radar to detect other vehicles approaching along the sides and monitors blind spots during lane changes. A towing package increases trailering capacity from 5,500 to 6,600 pounds, while the S-Line package adds a three-spoke leather steering wheel with shift paddles, aluminum inlays and 20-inch alloy wheels with high performance tires. Audiophiles with deep pockets will want to opt for the Bang & Olufsen audio system, which adds about $6,300 to the bottom line.
Audi's Q7 gasoline models have the latest powertrain innovations: Fuel Straight Injection (FSI) that contributes to spontaneous response and enhanced power, the quattro all-wheel-drive system, a six-speed Tiptronic transmission and a Dynamic Shift Program that adjusts gear changes to your driving style and road conditions. Premium unleaded fuel is recommended, but the 2010 Audi Q7 can operate on regular unleaded, although doing so results in a five-percent power loss. For those who seek better fuel economy there's the 3.0-liter TDI turbodiesel, which offers more pulling power than the V8 with better fuel economy than the V6.
3.6-liter V6
280 horsepower @ 6200 rpm
266 lb.-ft. of torque @ 2750 rpm
EPA city/highway fuel economy: 14/19
3.0-liter turbodiesel
225 horsepower @ 3750 rpm
406 lb.-ft. of torque @ 1750 rpm
EPA city/highway fuel economy: 17/25
4.2-liter V8
350 horsepower @ 6800 rpm
325 lb.-ft. of torque @ 3500 rpm
EPA city/highway fuel economy: 13/18
To compare current market prices, check out KBB.com's car classifieds to view the new and used Audi Q7 vehicles for sale near you.
Based on 109 Ratings for the 2007 - 2015 models.Review this car
By Screamrider on Wednesday, April 29, 2015
I own this car - My approximate mileage is 27,000overall rating 10 of 10rating details
Pros: "fun to drive, quiet, reliable"
Cons: "cup holders! hard to come up with cons"
Likely to recommend this car? (1-10): 10
"this is a big crossover with plenty of storage space, responsive handling and power. the diesel engine is quiet, clean and provides 26/28 MPG overall. rural driving with speeds around 45 MPH provides 30MPG! I knew two things going in 1)tires wear out around 30K miles, 2) brakes need work around 35K miles. I have 27K miles now and will need new tires by the time I hit 35K miles. however, my brakes are in good condition and should last until 50K plus. maybe it's just the way that I drive. if you need a safe, reliable, quiet, and responsive vehicle with a lot of carrying capability, this is the car for you."
71 people out of 117 found this review helpful
Was this review helpful to you? yes | no | report abuse
By Vegasjoe57 on Sunday, April 19, 2015
I own this car - My approximate mileage is 42,000overall rating 9 of 10rating details
Likely to recommend this car? (1-10): 9
"Drives and handles very well; overcomes slow acceleration of 6 cylinder with super chargers; wifi hotspot a must to pacify kids with their devices; 7 seats (Q7) works well for commuting and hauling kids but not for any long trips: not enough storage if the 3rd seat is down; wish the design of the container/drink holder between the 2 front seats was more functional; otherwise, this is a great driving vehicle; adaptive cruise control works very well but sometimes is annoying when cars pass you and then slow down in front of you: makes you rethink your interstate driving habits; only real complaint? tires seem expensive and they wear out fast: 20-25,000 miles max, at least, that's my experience."
16 people out of 21 found this review helpful
Was this review helpful to you? yes | no | report abuse
By Marie on Monday, March 09, 2015
I own this car - My approximate mileage is 1,500overall rating 10 of 10rating details
Likely to recommend this car? (1-10): 10
"I've had several SUV's and this one by far is the smoothest ride, great turning radius and is build SOLID!"
36 people out of 59 found this review helpful
Was this review helpful to you? yes | no | report abuse
By Ginny on Tuesday, January 20, 2015
I own this car - My approximate mileage is 32,000overall rating 9 of 10rating details
Pros: "2 of my neighbors now own Audis!"
Cons: "Lots of brake dust"
Likely to recommend this car? (1-10): 10
"I feel that the safety features in the Q7 better than Mercedes, Lexus, and BMWs that I have owned. It is my 2nd Q7."
42 people out of 71 found this review helpful
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By Ginger on Thursday, January 08, 2015
I own this car - My approximate mileage is 32,000overall rating 9 of 10rating details
Likely to recommend this car? (1-10): 4
"I have had Lexus, Mercedes, BMW. The power, safety features and appearance are hands down the best. The negatives I found were too much brake dust and poor rim choice. Highway mpg was 25-26 but requires high test gas. The articulating headlights in the mountains are a great extra feature"
5 people out of 12 found this review helpful
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By Lori on Saturday, July 19, 2014
I own this car - My approximate mileage is 13,000overall rating 10 of 10rating details
Pros: "very low mileage fun to drive"
Cons: "not a family car"
Likely to recommend this car? (1-10): 10
"Love this car , low miles, fast it's sports car . I know there is a demand for this car low miles, Has all the bells and whistles"
44 people out of 100 found this review helpful
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HIFF 2015 Schedule Now Online
The Halifax Independent Filmmakers Festival schedule is now online at HIFF.ca
Get a sneak peak at this year's selections by watching the HIFF mash-up trailer (https://youtu.be/VQcmCPecxi8).
HIFF 2015 showcases the best independent films from near and far from June 10-13 at Neptune Theatre's Scotiabank Studio Theatre. For the first time, all AFCOOP Full Members and Lifetime Members will receive a free pass to the festival.
Stay tuned to HIFF.ca, Twitter (@HIFF2015), and Facebook (facebook.com/HalifaxFilm) for announcements of visiting filmmakers, featured local shorts, and visiting programmers.
Send any questions to: firstname.lastname@example.com
Visit the HIFF web-site for more info.


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Derive a Template from a Running Trace (SQL Server Profiler)
SQL Server 2016
Topic Status: Some information in this topic is preview and subject to change in future releases. Preview information describes new features or changes to existing features in Microsoft SQL Server 2016 Community Technology Preview 2 (CTP2).
This topic describes how to create a trace template from an existing trace while it is running by using SQL Server Profiler.
To derive a template from a running trace
If necessary, switch to the window that contains the trace.
On the File menu, point to Save As, and then click Trace Template.
Type a name or select one from the list. Click OK.
If you select an existing template file, you are asked if you want to overwrite the file. You can only select a user-defined template. Predefined system trace templates cannot be overwritten.


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First impact of war on magic shadows--GeneralUchatius invents a projector combining Kircher's magic lantern and the Plateau-Stampfer picture disks--Motion pictures reach the screen.
THE FIRST MAN to combine Kircher's magic lantern and the Plateau-Stampfer disk and thereby achieve moving images on a screen visible to an audience was Baron General Franz von Uchatius. A type of bronze was named for this Austrian ballistic expert but, though his machine was the pattern for motion picture projectors until the advent of film at the end of the century, his name was not linked with the device. With Uchatius also came the first impact of projected pictures on the science of war. From these small beginnings, in less than a century, the motion picture --in our day--became a great weapon of psychological warfare.
Franz Uchatius, the second son of a former artillery officer and instructor in the cadet school who resigned after 19 years' service to become street commissioner in a small Austrian town, was born on October 20, 1811, at Theresienfeld, Wiener Neustadt, Austria. The father had married a woman from Bavaria and lived comfortably, for in addition to his town job he managed an estate and derived income from an agricultural sowing machine which he had invented.
After elementary and high school education near his home, Franz was apprenticed to a Viennese merchant. His father had to pay an annual fee of some 300 gulden (about $120) for the privilege. Franz, a small, sensitive boy, was very unhappy as an


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Laser in situ keratomileusisor LASIK is a commonly performed outpatient eye surgical procedure that is used as an effective treatment for many vision problems like hyperopia (farsightedness), myopia (near-sightedness), and astigmatism. However,LASIK eye surgery cannot reverse presbyopia, the age-related loss of close-up focusing power, which mainly affects near vision. Specifically, the ophthalmologist uses a laser to reshape the cornea, the clear covering of the front of the eye. This improves the way the eye focuses light rays onto the retina, at the back of the eye, allowing for better vision.
Scheme of the surgery-
In this procedure the patient is first made to recline under an excimer laser, the eyes are then made numb with anaesthetic, a speculum is placed between the eyelids to keep them from blinking and once the patient is ready the correction process is begun.
The surgeon first cuts a flap in the stroma (the cornea's middle layer) and then uses the laser to remove some of the tissue under the flap, reshaping the cornea. The flap is then replaced and the cornea is allowed to heal naturally. The whole procedure takes less than a few minutes per eye.
After surgery, you should avoid rubbing the eye and use an eye shield, to prevent the flap from shifting out of place.
Benefits of seeing better with LASIK-
As a safe and painless procedure it allows many people to perform most of their everyday tasks without wearing corrective lenses or eyeglasses.
LASIK eye surgery majorly involves lifestyle changes. All the advantages can be stumped into one word- Freedom. Patients are free to play, swim, dance, look through cameras or binoculars without having to take off their glasses or lens first.
However, as people age, visual acuity often continues to deteriorate regardless of corrective surgery as it only corrects vision and does not cure its underlying cause. As a result some people might again require glasses after surgery.
LASIK is not possible without health risks-
It is a surgical procedure and therefore carries inherent risks that range from major to minor and include:
Some of the problems that could develop due to the procedure include irregular healing of the flap, perforation of the cornea, mild infection or keratoconus (degenerative corneal disease) that could distort vision but this again varies from patient to patient.
LASIK induced dry eye syndrome is the most common drawback which can make daily activities like reading, working, riding etc. physically miserable. This painful suffering can be diminished using prescribed eye drops like Restasis.
Visual aberrations might occur after the surgery which include halos and glare under dim lighting conditions, impaired night vision, fluctuations in vision sharpness and chronic eye pain and irritation that severely interfere with normal activities.
Awareness in candidates undergoing LASIK eye surgery-
It cannot provide perfect vision but can improve it and reduce the need for eye wear. It is not a fail-safe procedure and may require re-treatment to achieve optimal outcome. Candidates must be screened for the surgery through a comprehensive eye examination to ensure that they are ideal to undergo laser eye treatment.
Qualified ophthalmologists for surgery-
One should inquire about the experience and popularity of eye surgeons in the field of LASIK before opting for the refractive eye surgery. Don't be afraid to search around on google for the very best local surgeons. Good doctors are those that properly diagnose the patient with thorough eye assessment for any eye diseases, provide details of the procedure and offer the highest standards of vision care. If you're in the Florida area, one resource that helped me is lasik eye surgery pensacola fl with lots of good reviews and recommendations.


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Tools Tests and Demos
Skew Chisel Sharpening
Keep your skew chisel razor-sharp and ready for turning. WOOD's turning expert, Brian Simmons, shows you how to shape, grind, and hone your skew chisel.the flat stone. And then raising they handle. I insured two point contacts system . To slide back and forth. Across the sound. I checked my progress often to ensure that I'm not raising able to high.
Bowl Gouge Sharpening
Woodturning expert Brian Simmons shows you how to put a razor-sharp fingernail profile edge on a bowl gouge.Keep the tour rolling at all times and -- rich create a flat spot on the level. Stop and check your progress so often. I'm looking for a clear. Uniform babble. From tip. To -- Without
Bowl Gouge Techniques
Woodturning expert Brian Simmons talks you through the simple steps for turning a bowl using a bowl gouge.I'll start being handled slightly below the tour rest. In with the cutting edge at center. Push the tool into the peace. Then swing the handle. All the tool out. Go to the left a little
Work Sharp demo in WOOD magazine shop
Kyle Crawford from Professional Tool Manufacturing demonstrates the fast, and nearly foolproof, Work Sharp power sharpening system.using is a slotted real. And corresponding slotted abrasives. So as the wheel spins . You can just look down through the spinning -- see the cutting edge that you're sharpening. And get amazing control. During the -- process so simply -- the slots of the abrasive. To the slotsground on that -- to. Great in my control to see the cutting edge while you're sharpening. So that's our solution for. Carving tools in -- tools -- in the slot at sea through -- We've
SawStop tablesaw demo
SawStop is a cabinet-style tablesaw that stops almost instantly when the blade makes contact with skin. Don't believe us? Watch this test video from the WOOD magazine shop.
Shop Tested: Loose Tenon Tools
Jeff Mertz demonstrates the four systems in this video. Learn the results of our testing of these jointmakers in issue 177 (July 2007) of WOOD magazine.
Impact Drivers
How impact drivers work and why you need one in your woodworking shop
Jointer/Planer Combo Machines
Tools editor Bob Hunter explains jointer/planer combination machines and shows how to convert them from one function to the other.mounted over the putter head -- got the -- machine set up accordion player mode with the dust that is covering the cutter head. The guards pulled back out of the way. Els who run the
Dust Collector Test
We tested a shop full of dust collectors for WOOD Magazine, issue 182. Jeff Hall walks you through our testing rig and methods.its vacuum pressure and that vacuum pressure or that resistance is called static pressure . Out of the box this year and it may pole. 11100 C at them but that's just the vacuum system part of it when we start adding resistance. -- clothes and bags. That they're being pulled end does it. Escape as readily as it's pulled it and therefore that's resistance. The more dot that we put in front of it to a machine. That's also resistance. All of that resistance built with the bags and duct work we need to overcome that static pressure that resistance. Would it CF them cubic feet per minute -- static pressure goes up our air logos down. To truly understand. The performance of a dust collector you need to plot. You're CF spam that's different static pressures and that's called Amkor. This is our test straight. And to do. Bad static pressure without adding -- We. Are increasing resistance of the air flow by closing off the opening of this dot. As we close that we increase the resistance and as we increase or resistancethree positions and they turned out to be the same as for static pressure and we recorded votes. We took these two readings this CFM. And the static pressure and we turn those. Into a fan curve. Here on the left side as we raise our static pressure or increase and ductwork or and its testing case we. Close the gap with the funnel to restricting air as we gave more resistance to this. Our curve went up port. When we started out with no resistance. To the right. We were polling more air -- air flow was the greatest on the right hand side. When we started adding. Resistance. Hard. Air flow decreased to move in sideways to the left and raising with more pressure. If I was going to use mind dust collector with a short amount a -- and move it from machine to machine I would want to greatest amount of air flow . That would be this machine has the most there. Poland through that machine. If I wanted to hook my machine up to a central duct work system. Then I would need to overcome more dot. Resistance. So of this chart here this curve. Is able to overcome more resistance and keep the high level of air flow I would want achieves this one or this one because it. Overcomes that resistance.
Craftsman CompuCarve Demo
WOOD Magazine Projects Editor Jan Svec demonstrates the capabilities of the Craftsman CompuCarve.and we will pick out these collect texture to. And pops open dialogue box and got a whole bunch of different textures which we can choose from. And wolf that kind of a simple one andthe project and loaded on to the memory card. Pops open a dialogue box here is the new file that we're going to load on would sign one and it gives us an estimated time that


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Viridioctopterus and Filixonida by HyrotrioskjanWatch
©2013-2016 Hyrotrioskjan
Two close relatives of Maluthorax: hyrotrioskjan.deviantart.com/a…
All species have a crest which have the form the plant they prefer to pollinate. Such extreme cases of adaption are common on Silvanus. The giant forests are full of micro-enviroments and because of the stable climate over a long time extreme forms of co-evolution are possible.
Silvanus frontpage: hyrotrioskjan.deviantart.com/a…
How may such micro-enviroments work?
I give you a example. In the root caves of Mundodendralis borealis live parasitic cuspipodids on the root juice. They only survive because they can digest the juice which is too sour for all of their relatives, they are hunted by specialized feelertongues which are able to navigate in the very narrow tunnels thanks to a thinner, more flexible exo-skeleton (the root caves of other species are mostly wider). Due to the thinner armor they can't survive in other Mundodendralis because they are no longer protected from the jaws of their relatives. The tunnles are also the home of small nocturnal flying pseudoathropods which sleep here during the day. A special fungo-like organism have made a business of this; it forms rod like structures which the pseudoathropods use to hang off. When they fly from rod to rod and from tunnel to tunnel they carry the spores of the organism with them. They also protect the rods from predators like the juveniles of the feelertongues and the shit they produce is a wonderful place for the cuspipodids to place their exouterus.
It's getting harder and harder to come up with original compliments for your works. You're so awesome I've used them all, lol.
I enjoy that you made these look almost leafy, especially on their crests
They look like they got some kind of funny helmet.Cool!
ausgezeichnet :iconclaplz:
Things on Silvanus just keep getting stranger and stranger.
wouldn't that crest really hinder flying?
These guys have smaller wings relative to their body, though. Or... I think. Can't really tell from this angle
Indeed, but you must remember the lower gravity and that this aniaml has 8 wings. Also it's important to know that the smaller/lighter a flying animal is the smaller it's wings can be. (no condor could fly with humming bird wings (propotional)
Ask Nyctosaurus....


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Lauren Brown distinuishes the College of Education
Academic adviser and licensure administrator in the College of Education, Lauren Brown is honored with the UofSC M. Stuart Hunter Award for Outstanding Teaching in University 101.
The Office of Communications collects and shares news about student, faculty, staff, alumni and college achievement and impact. Please let us know about your successes!
Academic adviser and licensure administrator in the College of Education, Lauren Brown is honored with the UofSC M. Stuart Hunter Award for Outstanding Teaching in University 101.
While the academic classroom setting has traditionally not been a place for children to get physical activity, Collin Webster and his team are seeking to change that.
UofSC College of Education and Children's Center STEM Fair Saturday, Oct. 24, 2015
The College of Education Dept. of Educational Studies has invited Dr. Vavrus to share her research insights on postcolonial education, critical development studies, and comparative teacher education in a public talk followed by a public forum at USC.
Alumni are invited to attend the university's homecoming celebration this year to celebrate the opening of the new Alumni Center
"This experience," Boutte says, "will allow me to gain firsthand experience, insights, and understandings about the dynamics in Nigeria in order to offer a more balanced view of Africa in general and Nigeria in particular."
He possessed a discerning disciplined presence befitting a leader. Lives depended on him. Lives were influenced by him. Dr. Charles H. Witten shaped the future for all he encountered.
M.Ed. in Educational Technology student and Richland Two high school math specialist one of 11 selected nationally for top honor
"I present my story," says Dr. Karen Worthy, "which is quite unique. I was a single, teen mother from a low-income, underrepresented population in rural Chester County, South Carolina..."
Dr. E. Doyle Stevick launches book at UNESCO-International Bureau of Education event in Geneva, Switzerland
The College of Education is proud to announce the achievements of two alumni who are shaping education at the highest levels nationally.
As a nationally accredited PDS institution, the college has forged an efficacious collaboration with fifteen P-12 partnerships.
This SC Educational Policy Center graduate research assistant was recently honored for using SAS technologies. in innovative ways
Kathleen Marshall and Tony Plotner were recently awarded $1.158 million to equip 12 Ph.D. scholars in special education with the newly-developed SC graduate endorsement in Transition Practices.
Get ready to sing along with and share this viral video hit in support of teaching science, technology, engineering and mathematics education careers.
Data-driven research presentations about what these future teachers have learned
I have a passion for helping others, especially those from under-served populations.
"Craig Kridel has a synoptic vision of education that is generous and caring, generative, wise, and humane..."
STEP offers students a hands-on, inquiry-based investigation of the world surrounding them.
Join us in honoring our high achievers and go-getters. We've got lots of them!
"I'm a storyteller. I am a teacher at heart" says William Hale.
The Gladys W. and David H. Patton College of Education at Ohio University believes in its people -- and supports their career development
TI-Nspire, CSI class, and assessment writing tips
The students said that they would love to go to a college class.
Dr. Thomas Hébert has been working with educators from Hampton, Colleton, Barnwell and Jasper counties.
SCEPUR distinguished paper entries were evaluated and selected based on the usefulness, significance, and educational interest of the topic as well as quality of the research, accuracy of data analysis, appropriateness of the presentation of results; validity of the content; and conformity to APA style.
Collaborate, investigate, analyze, qualify, quantify, mentor, evaluate, develop, inform, implement, and influence. These pursuits are what dedicated College of Education faculty, students and staff at college are revolutionizing daily.
Gonzalez will share her quirky, soulful, introspective journey through life as a promoter of creativity, culture, education and respect.
The School Improvement Councils (SICs) of seven South Carolina public schools have been named to the SC School Improvement Council's (SC-SIC) 2015 Honor Roll for their significant efforts to foster civic engagement in public education.
Earn a $300 stipend when you complete EDSE 210, a one credit-hour elective in which you will work in a local high school math and science classroom and explore teaching as a career.
Complete coursework toward your major, or take courses toward admission to the Secondary Master of Teaching Degree with summer classes.
U.S. News & World Report ranks our programs among the best nationally -- no surprise to us.
Bill Evans of Beaufort, Sherri R. Horton of Clifton, and Allison Batten Jacques of Columbia have recently joined the SC School Improvement Council Board of Trustees, Board Chair Michael Guarino has announced.
"I came to USC to design and deliver a new and challenging graduate program in gifted and talented education," says Professor Thomas P. Hébert.
Strong research requires the ability to formulate the right research question and identify relationships between information.
The Department of Educational Studies at USC's College of Education is now offering the university's first post-masters certificate in qualitative research.
Not only is Dr. Muller a faculty member, but also 22-year principal of Cutler Jewish Day School and an ordained rabbi.
Five students travel to Brazil, Taiwan, Ireland and Australia to gain professional experience in a once-in-a-lifetime opportunity.
Through a gift from the Duke Energy Foundation, the College of Education has launched a campaign to recruit more students to teach STEM curriculum at the middle and high school levels.
Professor Meir Muller presented, "Constructivist Family Engagement: The Wizard of Oz Conundrum" at the Jewish Early Childhood Education Leadership Institute.
McClanahan made the decision several years ago to be a life-long learner, and believes that teaching is the core of that pursuit.
Improving mathematics education, teacher education and teacher leadership remains resolute to College of Education researchers
Four diverse school districts in South Carolina came together last year to form a consortium recently awarded a $24.9 million grant in the second round of Race to the Top-District competition funding by the U.S. Department of Education.
"I became disturbed by the severe marginalization of women and girls in India - particularly in rural India," says Dr. Payal Shah.


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Starting my baby on jar food..
Life is not like a box of chocolates. It's more like a jar of jalapenos, What you do today might burn your ass tomorrow.
I alway started my boys with veggies. I think they had to have the same veggie for 3 days before we could move on to a new one. Good luck!
I wasn't trying to be rude, just shocked that any doctor would have a 3.5 month old already on cereal and starting jars.
reLLy* ...
We started on veggies (though we waited until 6 months and I assume you have reasons for wanting to start so early) and my son LOVES vegetables, 18 months later.
There is no reason to ever feed wheat (which is not even food) or corn (which is always genetically modified) to a baby. Rice is neither here nor there, but why feed a baby rice? Veggies are the way to go but really I'd advise everyone to wait until 6 months old.
More here:
I've started with fruit first and both of mine have eaten the veggies as well.
Chloe Lynn 3/6/2008 and Rylie Elizabeth 5/5/2011


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Searched for: "seven key types of security auditing"
Content Types
About 10 results for "seven key types of security auditing"
Be ready to mitigate disruptive tech's legal risks
With the cloud and big data in full swing and IoT on the rise, the time is ripe for businesses to take stock of the new legal challenges that disruptive technologies create.
LogicMonitor: SaaS network monitoring
Steven Trippe provides a detailed overview of the cloud-based LogicMonitor for network monitoring.
Schedule of 2012 trade shows and conferences in the U.S.
Interested in attending a trade show or conference in your area of IT? Here's a list of some of the top ones and the information you'll need.
Major security myths of 2009
2009 is just like any year in at least one way; too many people buy into too many security myths far too easily.
10 free security tools that actually work
Plenty of solid products are available to help you protect your system -- and some of them don't cost a dime. Here's a list of some of the most popular and effective free tools for defending yourself ...
10 things you should know about privacy protection and IT
These days, IT bears a tremendous responsibility for safeguarding corporate data and protecting personal privacy information. This overview shows just how entrenched privacy concerns have become in th...
Hacking your business partners
When this security firm was asked to do an evaluation of an International Bank's systems, they didn't know that their techniques would take them from hacking the critical application, to hacking the A...
Preempt security threats with testing and assessment tools
If you're in charge of disaster recovery planning, you also have to consider security threats that could put you in the recovery mode. Mike Talon discusses the preemptive moves you can make with the r...
Passing the e-Biz+ exam: Payment, performance, security
E-commerce sites need administrators who understand the intricacies of electronic business--and certs such as CompTIA's e-Biz+ are designed to help admins prove they have that knowledge. Here are some...
Lock IT Down: Broadband's cheap speed comes at a price of security risks
Overcome security risks associated with broadband connections


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Tight End
Height: 6-foot-2
Weight: 228 pounds
Class Year: Sr
Experience: 2V
Hometown: Tucson, AZ
High School: Pima CC
As a Recruit (profile)
Class: 2004 (Junior College)
Rating/Rankings: | NR
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The Latest: Wildcats excited for ASU game — 11/21/2006
In past years, the UA players have continuously described the Arizona-ASU contest as "our bowl game." That's not the case anymore. Both teams enter this year's rivalry game with 6-5 records, making each school bowl eligible. The importance of this year's game isn't lost on the UA players, who...[details]
Brad Wood College Videos
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Headlines from Rivals.com Network
Wildcats excited for ASU game — 11/21/2006, from GOAZCATS.com
Arizona pulls off improbable win — 11/12/2006, from GOAZCATS.com
Big win for Wildcats — 11/5/2006, from GOAZCATS.com
A.J. Simmons preparing for the future — 10/4/2006, from GOAZCATS.com
Game One Preview: Arizona vs. BYU — 9/1/2006, from GOAZCATS.com
Stoops talks starters, redshirts and more — 8/29/2006, from GOAZCATS.com
Arizona has options at tight end — 8/25/2006, from GOAZCATS.com
Thursday Practice Report: Morning — 8/17/2006, from GOAZCATS.com
Brad Wood working hard towards return — 8/16/2006, from GOAZCATS.com
Scrimmage a success for Willie Tuitama — 8/14/2006, from GOAZCATS.com
Saturday Scrimmage Report: Offense — 8/13/2006, from GOAZCATS.com
Thursday Practice Report: Offense — 8/11/2006, from GOAZCATS.com
Fall Camp: Day Two Notebook — 8/5/2006, from GOAZCATS.com
Plenty of standouts on first night of Fall Camp — 8/4/2006, from GOAZCATS.com
Voluntary Workout Recap: Offense — 7/13/2006, from GOAZCATS.com
Several Wildcats are prospects for 2007 NFL Draft — 5/15/2006, from GOAZCATS.com
Defense ahead of offense in first scrimmage — 4/1/2006, from GOAZCATS.com
Tight end looks forward to 2006 — 4/1/2006, from GOAZCATS.com
Notes and Thoughts: Injuries killed the Cats — 11/26/2005, from GOAZCATS.com
Mistakes, injuries do Wildcats in — 11/25/2005, from GOAZCATS.com
Football Roundtable: Oregon State Preview — 10/29/2005, from GOAZCATS.com
Arizona matches up well against Oregon State — 10/28/2005, from GOAZCATS.com
Arizona competes against top-ranked USC — 10/8/2005, from GOAZCATS.com
Arizona vs. USC: Keys to the game — 10/8/2005, from GOAZCATS.com
Arizona vs. California: Keys to the game — 10/1/2005, from GOAZCATS.com
Football Roundtable: Purdue review — 9/24/2005, from GOAZCATS.com
Football Notebook: Injuries piling up — 9/19/2005, from GOAZCATS.com
Arizona fans will have to wait for an upset — 9/19/2005, from GOAZCATS.com
Notes and Thoughts on UA's 31-24 loss to Purdue — 9/18/2005, from GOAZCATS.com
Football Roundtable Part II: Purdue preview — 9/17/2005, from GOAZCATS.com
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Question marks remain after win over NAU — 9/12/2005, from GOAZCATS.com
Notes and Thoughts on UA's 31-12 win over NAU — 9/11/2005, from GOAZCATS.com
Football Roundtable: Utah review, NAU preview — 9/7/2005, from GOAZCATS.com
Plenty of reasons to be optimistic despite loss — 9/5/2005, from GOAZCATS.com
Arizona played well, Utah played better — 9/4/2005, from GOAZCATS.com
Arizona adds local JC player to 2004 class — 5/26/2004, from GOAZCATS.com
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Slugabed - Ultra Heat Treated EP
Slugabed - Ultra Heat Treated E.P.
Reviewed by Colin McKean Source: (Fact Magazine)
From Sonny Boy Williamson's 'Sloppy Drunk Blues' to Primal Scream's 'Higher Than the Sun'; Bob Dylan's 'Rainy Day Woman' to Zomby's 'Spliff Dub', there is a rich tradition in popular song of tracks that not only chronicle overindulgence but actually inspire sensations associated with intoxification in the listener. Taking Drugs to Make Music to Take Drugs to is not just the title of Spacemen 3's greatest hits compilation: it's also a pretty succinct articulation of the band's modus operandi.
Last year, Slugabed's reworks of Rick James and ODB (neither exactly strangers to inebriation themselves, R.I.P.), sounded so heroically spannered it was hard not to wonder at the state in which the producer responsible for them was in. Now, on Mike Paradinas' Planet Mu label comes Slugabed's latest, the six-track Ultra Heat Treated EP.
Far be it from my place to speculate quite which influence(s) the young British producer may have been under when recording these tracks, but there's no two ways about it; this music sounds absolutely buckled.
From the start of the record, comparisons to Degenerate-era Vex'd and Starkey's street bass sound spring immediately to mind. The ferocious subs and keening synths of 'Ultra Heat Treated' sound barely tethered to a riddim that not so much lurches as hobbles. 'Skyfire' pings and whooshes like a mal-functioning arcade, the chopped squarewaves churning like the demented breakdown of Squarepusher's 'My Red Hot Car'. The influence of Tom Jenkinson is also audible in the howling synths of 'Pressure', which recalls the melancholy motif of 2002's Do You Know Squarepusher? set against a pistolwhip half-step skank.
The EP continues with the heaving post-Rustie chiptune of 'Quantum Leap' and the queasy, K-hole discombobulation of 'Goulash', before 'Titan' delivers you back towards a vaguely compos mentis, if garishly hypercoloured reality.
Slugabed is a supremely gifted producer. His stop-start synths and crunching, off-kilter beats result in productions that deftly combine melodic sensitivity with satisfying rhythmic complexity. It's probably safe to expect some big things from Slugabed in the near future, but for now, could someone please pass the Valium?
- Last Step - You're A Nice Girl
- Dolphin & The Teknoist - Soul Cannibal / Closing Down
- Bizzy B - Science EP Vol V
- Kyler - Pur Cosy Tales
- Hellfish - One Man Sonic Attack Force
- -
- Virus Syndicate - The Work-Related Illness
- Virus Syndicate - Slow Down
- Shitmat - The Lesser Spotted Burberry EP
- Bizzy B - Science EP Volumes III + IV
- Bizzy B - Science EP Vol IV
- Exile - Pro Agonist
- Vex'd - Degenerate
- Vex'd - Gunman
- John B & Exile - Broken Language
- Mark One - One Way
- Venetian Snares & Bong-Ra - 4 Adaptations Of Rossz Csillag Alatt Született
- Venetian Snares - Rossz Csillag Alatt Született
- Ed Lawes - 14 Tracks/Pieces
- Eight Frozen Modules - DJ, Riddim & Source E.P.
- dDamage - Pressure
- Bizzy B - Science EP Vol III
- Shitmat - Full English Breakfest


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Are you Haiwei Zhang?Claim your profile
Publications (13)47.15 Total impact
Article: FV‐429 Induced Apoptosis Through ROS‐Mediated ERK2 Nuclear Translocation and p53 Activation in Gastric Cancer Cells[Show abstract] [Hide abstract]
ABSTRACT: Following our previous finding which revealed that FV-429 induces apoptosis in human hepatocellular carcinoma HepG2 cells, in this study, we found that FV-429 could also induce apoptosis in human gastric cancer cells. Firstly, FV-429 inhibited the viability of BGC-823 and MGC-803 cells with IC50 values in the range of 38.10 ± 6.28μM and 31.53 ± 6.84μM for 24 h treatment by MTT-assay. Secondly, FV-429 induced apoptosis in BGC-823 and MGC-803 cells through the mitochondrial-mediated pathway, showing an increase in Bax/Bcl-2 ratios, and caspase-9 activation, without change in caspase-8. Further research revealed that the mitogen-activated protein kinases, including c-Jun N-terminal kinase, extracellular regulated kinase and p38 mitogen-activated protein kinase, could be activated by FV-429-induced high level ROS. Moreover, FV-429 also promoted the ERK2 nuclear translocation, resulting in the co-translocation of p53 to the nucleus and increased transcription of p53-regulated proapoptotic genes. FV-429 significantly inhibited the nude mice xenograft tumors growth of BGC-823 or MGC-803 cells in vivo. This article is protected by copyright. All rights reserved
Article: Wogonin Reverses Multi-Drug Resistance of Human myelogenous leukemia K562/A02 cells via Downregulation of MRP1 Expression by Inhibiting Nrf2/ARE Signaling Pathway[Show abstract] [Hide abstract]
ABSTRACT: Constitutive NF-E2-related factor 2(Nrf2) activation has been recently reported to play a pivotal role in enhancing cell survival and resistance to anticancer drugs in many tumors. Previously, much effort has been devoted to the investigation of blocking Nrf2 function in cultured cells and cancer tissues, but few research has been undertaken to evaluate the precise mechanism of flavonoids-induced sensitivity by inhibiting Nrf2. In this study, we investaged the reversal effect of Wogonin, a flavonoid isolated from the root of Scutellaria baicalensis Georgi, in resistant human myelogenous leukemia. Data indicated that Wogonin had strong reversal potency by inhibiting functional activity and expression of MRP1 at both protein and mRNA in adriamycin(ADR)-induced resistant human myelogenous leukemia K562/A02 cells. Consequently, the inhibition of MRP1 by Wogonin was dependent on Nrf2 through the decreased binding ability of Nrf2 to antioxidant response element(ARE). Further research revealed Wogonin modulated Nrf2 through the reduction of Nrf2mRNA at transcriptional processes rather than RNA degradation, which is regulated by the PI3K/Akt pathway. Moreover, DNA-PKcs was found to be involved in the Wogonin-induced downregulation of Nrf2 mRNA at transcriptional levels. In summary, these results clearly demonstrated the effectiveness of using Wogonin via inhibiting Nrf2 to combat chemoresistance and suggested that Wogonin can be developed into an efficient natural sensitizer for resistant human myelogenous leukemia.
Article: HQS-3, a newly synthesized flavonoid, possesses potent anti-tumor effect in vivo and in vitro[Show abstract] [Hide abstract]
ABSTRACT: HQS-3 is a newly baicalein derivative with a benzene substitution. We investigated the anticancer effect of HQS-3 in vivo and in vitro. HQS-3 significantly decreased tumor growth in mice inoculated with Heps and HepG2 cells; and had little influence on the state and weight of animals. After treatment with 20 mg/kg HQS-3, the inhibitory rate of tumor weight in mice inoculated with Heps and HepG2 cells were 63.62% and 68.03%, respectively. Meanwhile, HQS-3 inhibited the viability of various kinds of tumor cells with IC50 values in the range of 22.98 to 54.32 μM after 48 h treatment measured by MTT-assay. HQS-3 remarkably inhibited viability of hepatoma cells in a concentration- and time-dependent manner and induced apoptosis in HepG2 cells by DAPI staining and Annexin V/PI double staining. The apoptosis-induction effect of HQS-3 was attributed to its ability to modulate the actvity of caspase-9, caspase-3 and PARP. Moreover, the expression of bax protein was increased while the bcl-2 protein was decreased, leading to an increase in Bax/Bcl-2 ratio. The accumulation of ROS induced by HQS-3 in HepG2 cells was also observed. The further results suggested that HQS-3 induced mitochondrial-mediated apoptosis by increasing ROS level and inhibiting the expression of anti-oxidative protein SOD2. HQS-3 exerted anti-tumor activity both in vitro and in vivo via inducing tumor cells apoptosis, and these results suggested that it deserves further investigation as a novel chemotherapy for human tumors.
Article: Xu M, Lu N, Zhang H, et al.. Wogonin induced cytotoxicity in human hepatocellular carcinoma cells by activation of unfolded protein response and inactivation of AKT[Show abstract] [Hide abstract]
ABSTRACT: Aim: To investigate the potential anticancer effects of the natural flavonoid wogonin on human hepatocellular carcinoma (HCC) cells and tumor xenografts and the contribution of the unfolded protein response (UPR) and AKT pathways to the cytotoxicity of wogonin. Methods: The HCC cell lines HepG2, SMMC-7721 and Hep3B were treated with wogonin. 3-(4 5-Dimethylthiazol-2-yl)-2 5-diphenyltetrazolium bromide assays were used to evaluate the cell viability. Flow cytometry assays were used to identify the cell death types and measure the concentrations of intracellular H2 O2 and Ca(2+) . Western blotting assays were used to detect the protein expression levels of members in the UPR and AKT pathways. Relative quantitative real-time polymerase chain reaction assays were used to analysis the mRNA expression levels of chop and trb3. Furthermore, the male BALB/c nude mice with SMMC-7721 xenografts were treated with wogonin. The tumor volume, tumor weight and bodyweight were monitored during the tumorigenicity assays. Results: Wogonin significantly inhibited the viability of HCC cells by inducing apoptosis and necrosis. This cytotoxicity was at least partially attributed to the activation of the UPR pathway and consequent inactivation of AKT signaling, which resulted from the production of intracellular H2 O2 and causal release of endoplasmic reticulum Ca(2+) . Moreover, wogonin evidently repressed the growth of xenografts but slightly influenced the bodyweight of mice. Conclusion: Wogonin is a prospect for improving the systemic chemotherapy strategy on HCC by concurrently rectifying the aberrant UPR and AKT signaling pathways, which are crucial to the biology of HCC.
Article: Effect of magnetic nanoparticles of Fe3O4 and wogonin on the reversal of multidrug resistance in K562/A02 cell line[Show abstract] [Hide abstract]
ABSTRACT: Multidrug resistance is the main obstacle to the efficiency of systemic chemotherapy against hematologic malignancy. This study investigated the reversible effect of the copolymer wogonin and daunorubicin coloaded into Fe(3)O(4) magnetic nanoparticles, and the mechanism potentially involved. The growth inhibition rate of K562/A02 cells was investigated by MTT assay, and apoptosis of cells and the intracellular daunorubicin concentration were detected by flow cytometry. Distribution of nanoparticles taken up by K562/A02 cells was observed under a transmission electron microscope and demonstrated by Prussian blue staining. The transcription level of MDR1 mRNA and expression of P-glycoprotein were determined by reverse transcriptase polymerase chain reaction and Western blotting assay, respectively. The reversible effect of daunorubicin-wogonin magnetic nanoparticles was 8.87-fold that of daunorubicin + wogonin and of daunorubicin magnetic nanoparticles. Transmission electron microscopy and Prussian blue staining revealed that the nanoparticles were located in the endosome vesicles of cytoplasm. Also, the apoptosis rate and accumulation of intracellular daunorubicin in the daunorubicin-wogonin magnetic nanoparticle group were significantly higher than that in the daunorubicin, daunorubicin + wogonin, and daunorubicin magnetic nanoparticle groups. Furthermore, transcription of MDR1 mRNA and expression of P-glycoprotein in K562/A02 cells were significantly downregulated in the daunorubicin-wogonin magnetic nanoparticle group compared with the other groups. These findings suggest that the remarkable effects of the novel daunorubicin-wogonin magnetic nanoparticle formulation on multidrug resistant K562/A02 leukemia cells would be a promising strategy for overcoming multidrug resistance.
Article: Activation of the unfolded protein response contributed to the selective cytotoxicity of oroxylin A in human hepatocellular carcinoma HepG2 cells[Show abstract] [Hide abstract]
ABSTRACT: Hepatocellular carcinoma (HCC) is a refractory malignancy with a high incidence and large mortality. Current strategy for the chemotherapy of HCC focuses on developing agents with better efficacy and lower toxicity. In this study, we demonstrated that the natural flavonoid oroxylin A preferentially inhibited the viability of HCC cell line HepG2 but not the normal hepatic cell line L02. In HepG2 but not L02 cells, oroxylin A induced substantial production of intracellular H₂O₂ and inordinate activation of the PERK-eIF2α-ATF4-CHOP branch of the unfolded protein response (UPR) pathway, which resulted in the induction of TRB3 and causal reduction of p-AKT1/2/3 (Ser473). Moreover, these effects were eliminated by either the stable knockdown of CHOP or the pretreatment and then co-incubation with the specific H₂O₂ scavenger catalase. These results indicated that the H₂O₂-triggered overactivation of the UPR pathway and causal inactivation of AKT signaling contributed to the preferential cytotoxicity of oroxylin A in malignant HepG2 cells. Therefore, present study proposed an underlying molecular mechanism that implicated the selective antitumor effect of oroxylin A and recommended oroxylin A as a prospect for improving the current chemotherapeutic strategy for the treatment of HCC.
Article: VI-14, a novel flavonoid derivative, inhibits migration and invasion of human breast cancer cells[Show abstract] [Hide abstract]
ABSTRACT: It has been well characterized that flavonoids possess pronounced anticancer potentials including anti-angiogenesis, anti-metastasis, and pro-apoptosis. Herein, we report, for the first time, that VI-14, a novel flavonoid derivative, possesses anti-cancer properties. The purpose of this study is to investigate the anti-migration and anti-invasion activities of VI-14 in breast cancer cells. Our data indicate that VI-14 inhibits adhesion, migration and invasion of MDA-MB-231 and MDA-MB-435 human breast cancer cells. MDA-MB-231 cells treated with VI-14 display reduced activities and expressions of ECM degradation-associated proteins including matrix metalloproteinase 2 (MMP-2) and 9 (MMP-9) at both the protein and mRNA levels. Meanwhile, VI-14 treatment induces an up-regulated expression of tissue inhibitor of metalloproteinase 1 (TIMP-1) and 2 (TIMP-2) in MDA-MB-231 cells. Western blotting results show that phosphorylation levels of critical components of the MAPK signaling pathway, including ERK, JNK and P38, are dramatically decreased in VI-14-treated MDA-MB-231 cells. Furthermore, treatment of VI-14 significantly decreases the nuclear levels and the binding ability of nuclear factor-kappa B (NF-κB) and activator protein-1 (AP-1). Taken together, our data suggest that VI-14 treatment suppresses migration and motility of breast cancer cells, and VI-14 may be a potential compound for cancer therapy.
Article: Gambogic acid inhibits tumor cell adhesion by suppressing integrin β1 and membrane lipid rafts-associated integrin signaling pathway[Show abstract] [Hide abstract]
ABSTRACT: Cell adhesion plays an important role in the steps of cancer metastasis. Regulation of cell-cell (intercellular) and cell-matrix adhesion is a promising strategy for cancer progression. Gambogic acid is a xanthone derived from the resin of the Chinese plant Garciania hanburyi, with potent anti-metastasis activity on highly metastatic cells. The aim of this study was to investigate the function and mechanism of gambogic acid on tumor adhesion. We found that gambogic acid strongly inhibited the adhesion of human cancer cells to fibronectin. This inhibition was associated with the deformation of focal adhesion complex, which was mediated by suppressing the expression of integrin β1 and integrin signaling pathway. In vitro, cell lipid rafts clustering was inhibited following treatment of gambogic acid, which induced the suppression of integrin β1 and focal adhesion complex proteins colocalization within rafts. Moreover, gambogic acid significantly decreased cellular cholesterol content, whereas cholesterol replenishment lessened the inhibitory effect of gambogic acid on cell adhesion. Real-time PCR analysis showed that gambogic acid reduced mRNA levels of hydroxymethylglutaryl-CoA reductase and sterol regulatory element binding protein-2, while increased acetyl-CoA acetyltransferase-1/2. Taken together, these results demonstrate that gambogic acid inhibits cell adhesion via suppressing integrin β1 abundance and cholesterol content as well as the membrane lipid raft-associated integrin function, which provide new evidence for the anti-cancer activity of gambogic acid.
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ABSTRACT: The formation of a β-catenin·TCF4 complex in the nucleus of cells is well known as a prerequisite for the transcription of Wnt target genes. Although many co-factors have been identified to regulate the activity of the β-catenin·TCF4 complex, it remains unclear how the complex association is negatively regulated. In this study, we report that p15RS, a negative regulator of the cell cycle, blocks β-catenin·TCF4 complex formation and inhibits Wnt signaling. We observed that p15RS interacts with β-catenin and TCF4. Interestingly, whereas the interaction of p15RS with β-catenin is increased, its interaction with TCF4 is decreased upon Wnt1 stimulation. Moreover, overexpression of p15RS reduces the interaction of β-catenin with TCF4, whereas the depletion of p15RS enhances their interaction. We further demonstrate that overexpression of p15RS suppresses canonical Wnt signaling and results in retarded cell growth, whereas depletion of p15RS shows an enhanced effect on Wnt signaling. We analyzed that inhibition of Wnt signaling by p15RS leads to decreased expression of CYCLIN D1 and c-MYC, two Wnt targeted genes critical for cell growth. Our data suggest that p15RS inhibits Wnt signaling by interrupting β-catenin·TCF4 complex formation and that Wnt signaling initiates downstream gene expression by removing p15RS from promoters.
Article: Dishevelled-DEP domain interacting protein (DDIP) inhibits Wnt signaling by promoting TCF4 degradation and disrupting the TCF4/β-catenin complex[Show abstract] [Hide abstract]
ABSTRACT: The TCF4/beta-catenin complex, the executor of canonical Wnt/beta-catenin signaling, is regulated by a variety of factors. Among these, Dishevelled (Dvl) is a critical regulator that releases beta-catenin from degradation and stabilizes TCF4/beta-catenin complex. Here, we report that DDIP (Dishevelled-DEP domain Interacting Protein, also named as Spats1, spermatogenesis associated, serine-rich 1), a novel protein that interacts with Dvl, regulates Wnt signaling. We provide evidence that DDIP suppresses Lef-1 luciferase reporter activity stimulated by Wnt1, Dvl2 or beta-catenin, interacts with the TCF4/beta-catenin complex, and disrupts the interaction of TCF4 and beta-catenin by promoting TCF4 degradation through the proteasome pathway. Our results indicate that DDIP is a negative regulator of the canonical Wnt signaling.
Article: Oroxylin A inhibits angiogenesis through blocking vascular endothelial growth factor-induced KDR/Flk-1 phosphorylation[Show abstract] [Hide abstract]
ABSTRACT: In this study, we examined the antiangiogenic effect of oroxylin A in vitro and in vivo and explored the potential mechanisms for this effect. Transwell assay and tube formation assay were used to evaluate the effects of oroxylin A on vascular endothelial growth factor (VEGF)-induced migration and tube formation of human umbilical vein endothelial cells (HUVECs). Rat aortic ring assay was also employed to assess the effect of oroxylin A on microvessel outgrowth from rat aorta. Human tumor xenografts model in nude mice was further used to investigate the antiangiogenic activity of oroxylin A in vivo. Western blot analysis was used to investigate the related mechanism. Oroxylin A remarkably suppressed the VEGF-stimulated migration and tube formation of HUVECs. It also inhibited microvessel sprouting from rat aortic ring in vitro. In addition, it suppressed the angiogenesis of xenograft tumor in nude mice, which concurred with the inhibition of tumor growth. Moreover, oroxylin A blocked VEGF-induced phosphorylation of KDR/Flk-1 and related downstream signaling molecules, including p38 mitogen-activated protein kinase, extracellular signal-regulated kinase and Akt. Oroxylin A possessed antiangiogenic activities in vitro and in vivo, which could be an underlying mechanism of its anticancer effect.
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ABSTRACT: Varp, a novel protein containing a VPS9 domain and ankyrin repeats, can function as a guanine nucleotide exchange factor (GEF) of Rab21. We previously reported that Varp plays an important role in the regulation of endosome dynamics. To further investigate the function of Varp, a yeast two-hybrid screen was performed and Rab38 was identified as a Varp-associated protein. We demonstrate that Varp physically interacts with Rab38, and preferentially binds to the active GTP-bound form of Rab38 both in vitro and in vivo. Furthermore, Varp was shown to be recruited to Rab38-positive organelles in an ankyrin-repeat 1 (ANK1)-dependent manner. Our data demonstrate that Varp is a potential effector of Rab38. Together with our previous study, we propose Varp serves as both an effector and a GEF by interacting with different Rabs in mammalian cells.
Article: Endostar Suppresses Invasion Through Downregulating the Expression of Matrix Metalloproteinase-2/9 in MDA-MB-435 Human Breast Cancer Cells[Show abstract] [Hide abstract]
ABSTRACT: Endostar, a novel recombinant human endostatin expressed and purified in Escherichia coli with an additional nine-amino acid sequence forming another his-tag structure, was approved by the State Food and Drug Administration of China (SFDA) in 2005 for the treatment of non-small-cell lung cancer. However, the molecular mechanism of its potent anticancer activity remains poorly understood and warrants further investigations. In this study, we examined the anti-invasive activities of endostar in vitro. The results showed that endostar suppressed MDA-MB-435 cell adhesion to the fibronectin-coated substrate in a concentration-dependent manner. It could inhibit the wound healing migration of MDA-MB-435 cells and invasion of MDA-MB-435 cells through reconstituted ECM (matrigel). Zymography revealed that endostar decreased the secretion of MMP-2 and MMP-9. Endostar could also inhibit the expressions of MMP-2 and MMP-9 in MDA-MB-435 cells. Additionally, endostar exerted an inhibitory effect on the phosphorylation of ERK1/2. Collectively, these data provided a molecular basis for the anti-invasive effects of endostar.
Top Journals
China Pharmaceutical University
Nan-ching-hsü, Jiangxi Sheng, China
- • Jiangsu Key Laboratory of Carcinogenesis and Intervention
- • Department of Physiology
Society for Experimental Biology & MedicineSociety Hill, New Jersey, United States


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Posts Tagged: Tabatha Yang
The Beauty and the Beetles
You've heard of "The Beauty and the Beast?" A fairy tale? How about "The Beauty and the...
A ladybug (lady beetle) graces salvia. (Photo by Kathy Keatley Garvey)
This bedazzled beetle was worn as a living brooch and originated from Mexico.
Now That's Huge!
The world's largest hornet (Vespa mandarinia) is huge. Just how huge? We photographed a...
The world's largest hornet next to a honey bee. (Photo by Kathy Keatley Garvey)
The Monarch and the Mantis
It happened so quickly. The monarch butterfly (Danaus plexippus) fluttered to the lantana for a...
A praying mantis leaps at a fluttering butterfly. (Photo by Kathy Keatley Garvey)
With its viselike grip, the praying mantis holds on to its prey. (Photo by Kathy Keatley Garvey)
The praying mantis tightens its grip. (Photo by Kathy Keatley Garvey)
The monarch, mangled from its encounter with the praying mantis, didn't make it. (Photo by Kathy Keatley Garvey)
No-See-Ums, But You Feel 'Em
It happened unexpectedly. Tabatha Yang and her six-month-old son, Karoo, were sitting on their...
No-see-um, 70 times life size. (Illustration by Lynn Kimsey)
Even after five days, the bites are still visible. (Photo by Kathy Keatley Garvey)
Moths on Moth-ers Day
Saturday, May 11 is "Moth-ers Day" at the Bohart Museum of Entomology, University of California,...
A noctuid cutworm, which will turn into a "dull brown moth," crawls on yarrow in the UC Davis Arboretum. (Photo by Kathy Keatley)
This moth, detected in the UC Davis Arboretum, is a Plume Moth, family Pterophoridae. "It has a very characteristic way of folding its wings lengthwise and holding them perpendicular to the body," said Robbin Thorp, UC Davis emeritus professor of entomology. (Photo by Kathy Keatley Garvey)


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Zatana and Dragon by daxiongWatch
©2012-2016 daxiong
Inked then digitally colored
That's stunning. Is that a Japanese dragon style?
Okay, now this rocks.
Beautiful detail and such lovely color.
Amazing work!
excelent work!!! i love it!!!
This is absolutely stunning! Love the colors, the pose, everything about this artwork!
zatana she is hot girl wow!
what a lovely color~ like it~~
Wonderfully done!
*gapes* Radiant...absolutely gorgeous.
gorgeous work!
Wow, this is just absolutely stunning!!! The colors, the pose, the line art... Wow. I haven't been this blown away by a piece in a long time. Thank you for sharing this fabulous artwork!!
simply outstanding
Oh man. This is awesome!
if leonardo da vinci were alive he would bow himself at your feets. great!
amazing as always. Hope to see a Batman piece soon!
Awesome work!
Wow....AMAZING IN EVERY WAY!
great shading and color wow well done
Strikingly beautiful
Very nice


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AC / Blower Motor/ Actuators 2009 Ram
Im having problems w/09 Ram Quad Cab. Blower motor quits on start up, Actuators make noise, I get heat out of one side and AC from drivers while AC is on ??? In the Winter its just the opposite. Bought this truck used froM dealer a year ago and guess what...... IM .........ed. I ve had it in twice, 2 different dealers, both want $1000.00 minimum to tear dash apart, fix actuators. Love the truck , but its turning into a LEMON. Guess Im tearing into it myself. Thanks DODGE
Any Dash Schematics out there?
Hey before you pay to get it looked at, check and see if it meets the recall that was done a while back. My actuator went out in my used dodge 3 months after i bought it. it made a loud clicking noise and was stuck on heat. I believe the recall number is K17. I took it in and the recall was already satisfied on my truck before i purchased it, but they went ahead and completed it again, no charge.
AC / Blower/ Actuators
Thanks, I will take it in again. Why wouldn't the dealer have brought that TSB # up??? Don't they get paid by Dodge for these things. ? Is a TSB a recall???? Appreciate your input.
Do a search on your problem. Check the HVAC section for the 4th gen's. I posted a guide on how to replace the motors for blend doors. If it is just the motor for the blend door it will cost about $40 from chrysler.
The recall might have already been satisfied on your truck so when they pull up the info, it doesn't flag for them to perform it. I researched my symptoms on this forum and other sites and that is what it was. Your symptoms sound very similiar. I brought the truck to them and told them it is a problem with the actuator and to perform the recall (even though it was already done on my truck before i owned it). And that's what they did. Maybe you need to tell them to do it or they won't...
Dodge dealers give recall service bad taste!!!
:att:Unbelievable!!! Took 09 Ram Truck to dealer,3RD TIME (Dodge of Burns.)Showed and described the HVAC recall symptoms TSB- K-17 recall, and the service Advisor continually deny's that my truck symptoms are not part of the recall. Do I not understand ENGLISH!!!!!!!!!!!!!!!! What part of this am I missing. This truck had this recall fixed in 2010 before I bought it. It clearly needs the same recall fix again. WHATS UP WITH THIS. OR THE DEALERS.
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Tasty, healthy treat!
posted 7 years ago
I love all things Nutro! Their foods and treats have been proven to be very healthy for one of my dogs that has food allergies.
Pros: healthy
Cons: none
1 of 1 people found this review helpful.
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I love these Nuto treats!!!
posted 8 years ago
I love Nutro, they make there products with very healthy ingrediants! These treats are healthy and all of my dogs love the taste! I have told many of my friends about this product and they love it to!!!
Pros: These treats keep there teeth white!!
Cons: I have no cons about this product.
0 of 0 people found this review helpful.
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Excellent snack!
posted 7 years ago
This is an excellent snack for dogs who cannot eat the "usual" brands because of having a sensitive stomach. The natural taste is also a reason why I purchase this product for my dog.
Pros: Great for dogs who cannot eat "usual" brands, delicious
Cons: None I can think of at this time!
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June 8, 2015 | By Lynn
I've used this product on rescued dogs for years. My last large dog rescued had been an outdoor dog her entire life, living among Lamas where she picked up tapeworms. This product expelled several 2 … more ›
November 15, 2014 | By Robyn
July 14, 2013 | By Xiaoxiao111
Pink is my favorite color these are wonderful.I will recommend a good website fou you: www.9footballshirt.org


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Agreed, Lambert would be a very, very cool name . . . for a rockweiller.Originally Posted by Ghost
Agreed, Lambert would be a very, very cool name . . . for a rockweiller.Originally Posted by Ghost
No one has named their dogs or pet any of the following:
Mad Dog
Hammer (Jack Ham)
Torpedo (Shell)
Iron Mike
2.58 )
The referee said that you hit Brian Sipe too hard. Did you hit him too hard?
I hit him as hard as I could - Jack Lambert
Lambert would have to be a Rottie or a Doberman or a Pit Bull or something like that.Originally Posted by proudpittsburgher
Pomeranians or Chihuahuas or Bichon Frise need not apply.
There is always this dog, though:
What you've just said is one of the most insanely idiotic things I have ever heard. At no point in your rambling, incoherent response were you even close to anything that could be considered a rational thought. Everyone in this room is now dumber for having listened to it. I award you no points, and may God have mercy on your soul.
2015 MNF Executive Champion!
man, even PETA reps would say, yea, we gotta put this one down.Originally Posted by RuthlessBurgher
I just got a Bassett for the kids and the names came down to Jerome, Parker, & Crosby. Crosby won out but it was a close race!!!


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iHerb Customer Reviews
Great product!
2 people found the following review helpful
Posted by 4726813450520613720 on Jan 29, 2013
Love it! Small size makes it very comfortable to use. Don't forget to wash your face with soap before using wax strips, otherwise it won't work
1 person found the following review helpful
Posted by Reviewer1609084 on Aug 03, 2010
These are great for eyebrows.Fast and effective. But due to shape of stripes (rectangular) you might need to touch ups to give perfect shape. It does the most and you just need to touch up. Will order this again and will order bigger ones to my upper lips too.
1 person found the following review helpful
Posted by NinaNystuen on Sep 19, 2013
Works well, but it is a bit har to shape the eyebrows as you'd like to. requires patience.
Posted by 5681904499118748901 on Jul 17, 2014
Good strips! Better than HairOff!
No fuss and so easy
Posted by 5663612056424236187 on Sep 18, 2014
I tried this instead of heating up sugar wax and messing about with that, always takes so long but using these is super quick. A motivation to keep awesome looking brows!