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Apt. in 4* Alpinus complex, Acoteias, Albufeira
from £38 /night help Price for guests, Nights
11 reviews
from £38 /night help Price for guests, Nights
Estimated nightly price based on a weekly stay. Excludes fees (if applicable). Enter your dates to see the total cost.
Apartment / 1 bedrooms / sleeps 4 Home 476711
Availability Your dates are available
Apartment / 1 bedrooms / sleeps 4
|Key Info
This modern apartment is situated in the 4 star Alpinus Falesia Suites Hotel, in the Acoteias area of Albufeira. The hotel is set in -tree gardens and has 4 swimming pools (2 adults and 2 children) with a games area and plenty of space for sunbathing.
This privately owned self catering apartment is beautifully decorated and has a double bedroom and two sofa beds to sleep up to 4 people. Ideally suited for families as the on site facilities mean you can have a great holiday by the pool or enjoy the entertainment in high season. The living area has a TV, CD player and DVD player with a selection of films. There is a small safe free for your use in the bedroom. The apartment benefits from beautiful views over the grounds of the Sheraton Pine Cliffs. FREE WIFI in the apartment.
There is also free Wifi in the Reception area, a Play Station plus great fun games by the pool such as Snooker, Pinball Machine, Table Football & Ice Hockey.
In the kitchen there is an oven, 2 rings, coffee machine, toaster and a microwave so you can enjoy dining al fresco on the balcony or you could opt to use the buffet restaurant or coffee shop in the Apart Hotel. A selection of restaurants, bars and supermarkets are within easy walking distance from the hotel.
A free shuttle bus is available to take you to the beach and into Albufeira. If you don't want to pack many clothes there is a self service laundrette within the complex too.
Falesia Beach is located not far from the apartment (1km), within easy walking distance , and is the only golden awarded beach in Portugal for its clean warm water. It stretches for 8 km and has all the water sports on offer; you can also hire parasols and sun loungers daily.
The 24 hour reception can book car hire, book excursions and give you advice about interesting things to do in the area. In Acoteias there is an excursion shop also. There are lots of days out to interest everyone. Go to one of the popular waterparks – Splash and Slide, Aqualand and Aqua Show. Go to Krazy World in Algoz, Go Karting in Almancil, visit the Sand Sculptures just outside Pera or go on a day out to the local markets where you might pick up a bargain. Bicycles are also available to hire for the excursion shop.
Very popular with holiday makers is a day out at Zoo Marine, a large oceanographic theme park based on environmental conservation and education. This outstanding marine zoological centre has a cinema, a large aquarium and a marine museum. It also stages live shows, including the popular "interaction with dolphins" programme, where visitors over 6 years old are allowed to interact in the water with trained bottle-nosed dolphins. There is also an amusement park, swimming pools, picnic area, shops and restaurants
For those who love shopping there are two large shopping complexes, Algarve Shopping at Guia and Faro Shopping in Faro. There is regular local transport available, with a bus stop immediately outside the Alpinus Hotel. Taxis are also readily available, reception will order you one if you request it.
For golfers, the Algarve has a wide selection of high quality golf courses to suit all needs. The 5 star Sheraton Pine Cliffs has a pine tree lined 9 hole course, driving range, chipping and putting areas, a golf academy for lessons and a club house for a cooling drink after your game. Many other golf courses are available, particularly a short taxi ride away near Vilamoura.
A short taxi ride will take you to Albufeira, the strip or the Old Town. The strip is an area for lively holiday makers with numerous bars and restaurants lining the street. The Old Town is down near Fisherman's Beach. You can have dinner overlooking the sea or walk around and enjoy the atmosphere.
In the opposite direction, a short taxi ride will take you to Vilamoura, with it's famous Marina. Enjoy dinner overlooking the boats of the rich and famous and envy as the expensive sports cars drive past. From the Marina, many additional excursions can be booked like deep sea fishing, jet skiing, dolphin safaris, parasailing and the high adrenaline rocket ride.
Fully Inclusive packages can be bought at reception by guests.
|Sleeps up to 4, 1 bedrooms
|1 bedroom, 1 bathrooms of which 1 Family bathrooms, Solarium or roof terrace
|Nearest beach
|Beautiful Falesia Beach 1 km
|Car not necessary
|Nearest Amenities
|300 m
|Nearest travel links
|Nearest airport: Faro 36 km
|Family friendly
|Great for children of all ages
|No pets allowed, No smoking at this property
Features and Facilities
|Internet access, DVD player
|Shared outdoor pool (unheated), Children's pool
|Air conditioning, TV, CD player, Games room, Safe, Satellite TV, Wi-Fi available
|Kettle, Toaster, Iron, Hair dryer
|Clothes dryer, Cooker, Microwave, Fridge, Freezer
|Double Beds (1), Sofa Beds (2), Cots available (1), Dining seats for 4, Lounge seats for 4
|Linen provided, Towels provided
|Shared outdoor pool (unheated), Balcony or terrace, Shared garden
|Parking, Suitable for people with restricted mobility, Not suitable for wheelchair users
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17 Jan 2015
"A delightful winter vacation with all the comforts of home."
It was a perfect winter vacation in a warm, sunny climate. The apartment was attractive, well equipped, roomy, and sunny. It was possible to have lunch on the terrace the entire 4 weeks of my stay. The restaurants that were open in the vicinity of the hotel were excellent and reasonable. The surroundings were beautiful, great for walks and sunbathing on the beaches. Tours to places of interest were also a great plus.
Thank you for your kind review. We are pleased that you enjoyed yourself and you would be welcomed back anytime.
24 Sep 2014
"Fab apartment for relaxing break!"
Stayed at this apartment with friends last week and what a great apartment it was. Spotlessly clean on arrival, the apartment it lovely and spacious with modern decoration. It's well equipped for a self catering break, but near local bars and restaurants if you don't fancy cooking. Location wise it was great for a relaxing break, but with everything on your doorstop, supermarket minutes walk away along with a small selection of bars and restaurants. The complex also runs a free shuttle bus to Albufereira New and Old Town on a daily basis, and we found taxis back reasononable (approx €12 each way). There's also a gorgeous beach 10/15mins walk away with a small cafe/bar for a cold drink once you get there. Two pools to pick from and the apartment, with plenty of sun loungers to choose from. Wouldn't hesistate to book this place again if we head back to the Algave.
Thank you for your kind review. If I had the facility to rate my guests you would be a 5 star. Communication with you was prompt and problem free. I'm glad you and your guests had a good time. You are welcome back any time.
8 Aug 2014
"Fantastic apartment in a Perfect location"
The apartment is fantastic so well equipped that we felt it was home from home. There was a drawer of books , DVDs and spare travel adapters to borrow and lots of useful information on the local area. The kitchen has everything you could want or expect self catering . There was a compact vacuum cleaner which was great and also an abundance of wardrobe and cupboard space for a family of four ticked all the boxes. Travelling with teenagers the free wifi in the room was an added bonus. The apartment is in a really good position , there is a supermarket less than 5 minutes away with newspaper shops and an ATM . It was good to try all the local restaurants in the square to the fish restaurant close by and with self catering we weren't on a time schedule so we could relax and eat slightly later in the evening. Acoteias has the best beach and is 15/20 minute walk, passing supermarkets and the square with lots of cafés. There is a local bus stop outside the hotel to Albufeira or there is a hotel courtesy bus . I couldn't fault anything in the apartment . We all had a great relaxing time in a perfect location. Wish I was there now .
Thank you for your review. We are glad that you had a good holiday and you are more than welcome to stay again anytime.
6 May 2014
"Very clean large apartment. Wifi in appt a plus."
We stayed in this apartment during the month of April 2014 and were very pleased. We were a 15 minutes walk from the beach and it was worth ever step. The supermarkets were close by and provided good products and service.
Thank you for your booking and your kind review. Falesia Beach is indeed beautiful and worth every step it takes to get there. You are welcome back anytime.
3 Nov 2013
"Loved it - will definately be back !!"
The apartment is lovely - tastefully decorated with plenty of space throughout and a SOUTH facing good sized balcony. Full use of hotel facilities including bars and pools but only really made use of pool area. Glad I was'nt a hotel guest as most of them were all inclusive which meant they missed out on all the local bars/restaurants. Plenty of bars/restaurants a two minute walk away (as was supermarket/tobacconist/newsagent) and suffice to say at some point we visited most of them. Restaurants included local Portuguese, Italian, Chinese, steak house, tapas and some finer dining places. All places very friendly towards us. We stayed mid October so the general area was fairly quiet but if you wanted more life then Old Town Albufeira was a 11 Euro taxi ride away (22 return) and again well worth a visit. We booked the apartment at short notice and had a great time and would certainly book again.
Thanks for the review. We are glad you had a good time and tried some of the many local restaurants. You are welcome to return at any stage.
30 Sep 2013
"An excellent appartment to stay at."
It is the 6th time we have stayed in this appartment . The appartment has recently been upgraded which makes for a great holiday.All the mod cons you would expect for a great holiday.The appartment is close to cafes and restaurants,supermarkets,and takeaways. There are 2 beaches which can be reached by walking a short distance.We have friends who keep going back year after year. The view from the balcony over the sheraton golf course is really nice.we would certainly recommend this appartment to anyone.
Thank you for the review. We are grateful for all your bookings and look forward to you staying again in he future.
28 Sep 2013
"Prefect for couples and families"
This was the first holiday with our 11 month old and also the first holiday not booked through the usual travel agents. Everything went smoothly. The facilities are great. Local amenities close by and all very child friendly. The apartment was clean and spacious more than enough room for 3 adults and a baby. The information pack within the apartment was a nice touch and the apartment itself is very well equipped. Definitely going back.
Thank you for the review. We are glad you enjoyed staying at our apartment. You are welcome back anytime.
25 Sep 2013
"Excellent accommodation with all the facilities you need"
This accommodation is part of an hotel which is excellent as you have full use of the hotel pools. We travelled with our two children who are 11 and 14. The hotel is in a quiet location which suited us perfectly. There are good restaurants nearby. A 10 minute walk takes you to the local beach where there are more restaurant choices - the Pizza Restaurant here is excellent! Olhos d'Agua is a 5-10minute taxi ride - we loved the buzz here at night time - loads of restaurants, ice-cream shops and a beach here too. The apartment is lovely, fresh and clean and felt like a home from home. We thoroughly enjoyed our stay here.
Thank you for the booking and your review. We have to agree - the pizzas in the Italian restaurant near Falesia Beach are good. Glad you had a nice stay.
19 Sep 2013
"Very nice apartment and lovely nearby beach"
We had a great stay in Alpinus. The apartment was great although what the photo doesn't show is that the balcony is just overlooking a main road which runs right round the front of the hotel. So the views weren't great but the beach made up for that mainly. Falesia beacj is the closest one (10-15 mins walk) and it's a really clean and pleasant beach and wasn't at a crowded when we were there. There are nice restaurants near by as well so you have everything you need although it's not the prettiest of areas. We did find that the hotel reception were a little unwilling to help and advise us to begin with because we were in the 'private apartment' which we were reminded has nothing to do with the hotel. This wasn't too much of a problem over all but it didn't help welcome us much. The free shuttle bus which takes you into the main town and other beach was great but again, because we were staying in the private apartment, they put us at the bottom of the list and told us that if the bus was full we wouldn't be able to get on, even if we had reserved a spot in advance of others. This didn't feel great but luckily the bus was never full up. Over all a nice holiday though.
Thank you for the booking and your review. I am glad you had a good stay. You looked after the apartment well whilst there and we would welcome you back anytime. I will bring the issues at reception to the attention of the hotel manager. Thanks again.
This advert is created and maintained by the advertiser; we can only publish adverts in good faith as we don't own, manage or inspect any of the properties. We advise you to familiarise yourself with our terms of use.
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According to a recent Wall Street Journal article, sweating the small stuff can (and often does) ruin a marriage. The article says that though most people blame big challenges for toppling marriages -- it's more often the little annoyances that chip-chip-chip away. I've experienced this phenomenon with friends. Or should I say, former friends. I am one of those people who has no problem talking about things in the moment, so I tend not to hold on to little resentments until they fester. But I've had girlfriend breakups that began with the friend telling me I'd hurt her feelings in some way (usually with some thoughtless, snarky comment that got under her skin) and then having the conversation suddenly snowball as she brings up the mean thing I did four years ago -- that other bitchy thing I did in August, and so on. If there's one thing I've learned from those breakups, it's that by the time it gets to that point, the relationship is too far gone to be salvaged.
So takeaway 1: Talk about stuff right away.
The other thing I've learned is if I spend my time mentally picking Jack apart, I end up miserable. I mean we've all had those days where we focus more on our partners flaws than on their strengths. Is he perfect? No way. But he's perfect for me. So when I start silently criticizing him for the way he just...is (like how he drives, talks, moves way slower than I do, or the way he snores like a grizzly bear with seasonal allergies), I have to make a mental list of some of the things about him that I find adorable. Luckily, that list is long. Also luckily, the WSJ article totally cosigns this approach.
So, takeaway 2: Take a second to focus on the small stuff that you adore.
I mean, do you really want to let the fact that you hate the way he chews wreck your marriage?
-- Holly
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After being withdrawn from last weekend's Silver Slipper Stakes, the John O'Shea-trained Holler now heads the Skyline Stakes 2015 nominations for Warwick Farm this weekend.
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Vancouver is co-favourite to win the Group ...
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2015 Golden Slipper Dream Begins for Stay With Me
Victorian trainer David Hayes has very fond memories of Miss Finland and hopes to win this year's Golden Slipper 2015 with one of the mighty mare's progeny Stay With Me who debuts this weekend.
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A taste of the tropics will be welcomed by your holiday guests. The cool and creamy dip can be served as an appetizer or a dessert. —Shelly Fisher, Hermiston, Oregon
- 1 package (8 ounces) cream cheese, softened
- 1 jar (7 ounces) marshmallow creme
- 1 can (8 ounces) crushed pineapple, drained
- 1/2 cup flaked coconut
- Assorted fresh fruit or cubed pound cake
- In a small bowl, beat cream cheese and marshmallow creme until fluffy. Fold in pineapple and coconut. Cover and chill until serving. Serve with fruit or pound cake. Yield: 2-1/2 cups.
Originally published as Pina Colada Fruit Dip in Taste of Home Christmas Annual Annual 2009, p65
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Unisex Tank Top
Treehouseby Timothy J. Reynolds
American Apparel Tank Tops are made with 100% fine jersey cotton combed for softness and comfort. (Athletic Grey and Athletic Blue contain 50% polyester / 25% cotton / 25% rayon)
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Sacramento announces preliminary arena deal
Updated: March 24, 2013, 12:11 AM ETAssociated Press
SACRAMENTO, Calif. -- Sacramento city officials reached a preliminary agreement Saturday night for a new downtown arena with an investment group that hopes to keep the Kings from moving to Seattle.
Sacramento Mayor Kevin Johnson first announced the deal on his Twitter account. A few hours later, the city released the details of the non-binding term sheet.
The group includes Silicon Valley software tycoon Vivek Ranadive, 24 Hour Fitness founder Mark Mastrov and billionaire Ron Burkle. ...
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WASHINGTON -- It has been nearly six years since President Bush and Russian President Vladimir Putin memorably tooled around Bush's Texas ranch in a pickup truck and discussed missile defense.
That was shortly after Bush famously said he had glimpsed Putin's soul and felt that he and the Russian leader had a bond of trust. And it was before the Iraq War, which Putin opposed, and before Putin compared U.S. foreign policy to Nazi Germany's.
The missile defense system never materialized.
A few days ago, the two leaders had another go at it, meeting this time in Kennebunkport, Maine, at the Bush family compound, where they zoomed around in a speedboat with the elder President Bush. They also fished, played fetch with their dogs -- Putin brought along his Labrador -- and scooted around on Segway transporters.
There's no rule requiring that world leaders do guy things while ironing out issues -- nor any guarantee of outcome -- but it is a fact that men communicate best while engaged in nonthreatening activities, especially on neutral turf.
Out on the open range or at sea, the mind expands and the heart relents.
On the other hand, as America considers a woman president, perhaps good ol' boy conclaves create a false sense of bonding as men project imagined camaraderie over convivial pursuits. Bush's Texas truckin' diplomacy did not, in fact, do much good despite photos that showed him and Putin grinning like two Cheshires at a cheese factory.
Bush seemed to be having such a good time with Vlad riding shotgun that he may have missed the former KGB officer's subterranean animus toward the U.S.
If two men in a truck couldn't resolve differences, could three in a speedboat do better?
Speaking to reporters in Maine, Putin said, "The deck has been dealt, and we are here to play. And I would very much hope that we are playing one and the same game."
About their meeting, Bush said: "Do I trust him? Yes, I trust him. Do I like everything he says? No. And I suspect he doesn't like everything I say. But we're able to say it in a way that shows mutual respect."
They seemed ready to cooperate, in other words, but they've seemed that way before. One possible difference this time is that the two men may have recognized a common and more urgent challenge than before. Nothing like Iranian President Mahmoud Ahmadinejad to force clarity and perspective.
We know that Bush and Putin spent one-on-one time together and that they discussed Iran. One hopes that when the two men peered into each others' eyes, they said something like:
"Look, buddy, I don't like you much and you don't like me, but Ahmadinejad is a problem. Let's sort this thing out."
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Publications (9)34.91 Total impact
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ABSTRACT: Hematopoietic stem cell transplantation (HSCT) is an accepted treatment for a variety of hematologic malignancies. The profound immunosuppression these patients experience adversely affects their risk of infection. This risk is much higher than in the general population and requires aggressive diagnostic and therapeutic interventions. The chapter will outline the major infections after HSCT.
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ABSTRACT: As more solid organ transplantations are performed in patients infected with human immunodeficiency virus (HIV), post-transplant complications in this population are becoming better defined. Using serum samples from the Solid Organ Transplantation in HIV: Multi-Site Study, we studied the epidemiology of acquired hypogammaglobulinemia (HGG) after liver transplantation (LT) in 79 HIV-infected individuals with a median CD4 count at enrollment of 288 (interquartile range 200-423) cells/μL. Quantitative immunoglobulin G (IgG) levels before and after LT were measured, with moderate and severe HGG defined as IgG 350-500 mg/dL and <350 mg/dL, respectively. Incidence, risk factors, and associated outcomes of moderate or worse HGG were evaluated using Kaplan-Meier estimator and proportional hazards (PH) models. The 1-year cumulative incidence of moderate or worse HGG was 12% (95% confidence interval [CI]: 6-22%); no new cases were observed between years 1 and 2. In a multivariate PH model, higher pre-transplant model for end-stage liver disease score (P = 0.04) and treated acute rejection (P = 0.04) were both identified as significant predictors of moderate or worse HGG. There was a strong association of IgG levels <500 mg/dL with non-opportunistic serious infection (hazard ratio [95% CI]: 3.5 [1.1-10.6]; P = 0.03) and mortality (3.2 [1.1-9.4]; P = 0.04). These associations held after adjustment for important determinants of infection and survival among the entire cohort. These results suggest that a proportion of HIV-positive LT recipients will develop clinically significant HGG after transplantation.
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ABSTRACT: Due to the rising incidence of diabetes mellitus, the increasing populations of immunocompromised individuals of varied etiologies, and the progresses that have been made in the management of the critically ill, the incidence of invasive fungal infections, in particular those caused by the Mucorales, is increasing. Currently available diagnostics frequently miss this infection. Knowledge of the factors placing individuals at risk for and the varied clinical presentations of mucormycosis should alert clinicians of the possible presence of this infection. Survival of individuals with mucormycosis is dependant on prompt diagnosis and aggressive therapy with antifungal agents; surgical debridement; and, if possible, reversal of the risk factors predisposing the individual to this infection. It is hoped that improved diagnostic testing, improvements in pharmacotherapy, and adjunctive therapies will improve the morbidity and mortality of mucormycosis. KeywordsMucormycosis-Zygomycosis-Antifungal therapy
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ABSTRACT: Bone marrow and hematopoietic stem cell transplants are life saving procedures for a variety of hematologic malignancies. Unfortunately, long-term survival is significantly impacted by the development of invasive fungal and bacterial infections, in part attributable to innate and adaptive immunologic defects post-transplant. This review focuses specifically on neutrophil function after autologous and allogeneic bone marrow and hematopoietic stem cell transplant.
Conference Paper: Semiotics of 'Noncompliant' Patient.[Show abstract] [Hide abstract]
ABSTRACT: 'Noncompliant' (NC) patient is a common label in medical records. While it encapsulates many dimensions of undesired patient behavior, the semiotics by which it is generated and applied is unclear: What data indicate noncompliance? How are the data analyzed and interpreted to label a patient as noncompliant? How does the label frame the physician's thinking? How does it affect the physician's diagnosis, treatment, instructions and actions? How does it affect medical outcomes? This lack of semiotic clarity can result in medical errors. We provide a framework (a) for conceptualizing the semiotics of NC, and (b) to understand the sources of potential medical errors. We illustrate the framework with a case study. The framework can be used to manage noncompliance effectively and reduce medical errors, especially with EMRs.
Conference Paper: The Clinical Spectrum of BK Virus Infection after Hematopoietic Stem Cell Transplant (HSCT)[Show abstract] [Hide abstract]
ABSTRACT: Background: Hemorrhagic cystitis manifesting as gross hematuria (GH) is a well described BK virus associated syndrome after HSCT. Other BK virus associated syndromes, such as polyoma virus associated nephropathy (PVAN), are reported as cases in the HSCT literature. Data regarding the spectrum, incidence, treatment, and treatment response of BK virus associated syndromes in a large patient cohort are few. The primary aim of this study was to describe these features in a large cohort of allogeneic HSCT recipients. Methods: Charts of 115 allogeneic HSCT recipients were reviewed. Continuous variables were compared using the t-test. Results: 11 patients had gross hematuria (GH). In 6/11 cases, GH resolved without intervention. 2/11 cases required urologic procedures and the remaining 3 were treated with cidofovir. Mean urinary BK viral load (VL) was 17,349,496 copies/mL (c/mL) in GH cases and 5,615,542 c/mL in those without GH (p = 0.001). Mean blood BK VL was 9689 c/mL in GH cases and 78,208 c/mL in patients without GH (p = 0.18). 9 patients had cystitis symptoms other than GH (uncomplicated cystitis, UC). None required directed therapy. Mean urinary BK VL was 19,817,151 c/mL in UC cases and 5,055,767c/mL in those without UC (p < 0.0001). Mean blood BK VL was 11,380 c/mL in UC cases and 77,119 c/mL in patients those without UC (p = 0.20). 2 patients developed PVAN. Both were treated with leflunomide, required dialysis, and had urinary BK VLs greater than 25,000,000 c/mL and blood BK VLs greater than 100,000 c/mL persistently for over 6 months. Discussion: Our understanding of clinical syndromes associated with BK virus continues to evolve. Urinary BK VL was associated with all BK associated syndromes reported. In patients with UC, symptoms resolved without anti-viral treatment. PVAN was seen in 2.7% of the present cohort and may represent an emerging BK virus associated syndrome.
Article: BK Virus Infection Is Associated with Hematuria and Renal Impairment in Recipients of Allogeneic Hematopoetic Stem Cell Transplants[Show abstract] [Hide abstract]
ABSTRACT: BK virus (BKV) is an important pathogen and cause of nephropathy in renal transplant recipients, but its significance following hematopoetic stem cell transplantation (HSCT) is less well described. We measured blood and urine BKV in 124 allogeneic HSCT patients (67 had undergone prior HSCT [surveillance cohort]; 57 were monitored from transplant day 0 [prospective cohort]). BK viruria was manifest in 64.8% of the patients; 16.9% developed viremia. In the prospective cohort, the median time from transplantation to BK viremia development (128 days) was longer than for viruria (24 days; P < .0001). Among clinical factors (sex, disease, transplant type, alemtuzumab use, cytomegalovirus [CMV] viremia, graft-versus-host disease [GVHD], donor HLA C7 allele), only CMV viremia was more common in patients with BKV infection (P < or = .04). There was a direct relationship between blood and urine BKV levels and the occurrence, and degree, of hematuria (P < or = .03). Finally, BKV infection was analyzed along with other clinical factors in relation to the development of post-HSCT renal impairment. On multivariate analysis, only BK viremia (P=.000002) and alternative-donor transplantation (P=.002) were independent predictors of development of post-HSCT renal impairment, with BK viremia associated with a median 1.62mg/dL rise in creatinine from the pretransplant baseline. Among 8 patients in the surveillance cohort with BK viremia, 2 developed biopsy-proven BKV nephropathy requiring hemodialysis. Investigation of whether prophylaxis against, or treatment of, BKV in the post-HSCT setting mitigates the associated morbidities, especially kidney injury, warrants prospective evaluation.
Top Journals
University of Chicago
Chicago, Illinois, United States
- • Section of Infectious Diseases and Global Health
- • Department of Medicine
Kaiser Permanente
Oakland, California, United States
- Section for Infectious Diseases
The University of Chicago Medical CenterChicago, Illinois, United States


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Emergency response
Life can change for millions of families in an instant: natural disasters take loved ones and the outbreak of war drives families from their homes. When the unthinkable happens, Mercy Corps delivers rapid, lifesaving aid to hard-hit communities and then teams up with them to build back stronger.
We have responded to almost every global natural disaster in the last 20 years, including the Nepal earthquake, Typhoon Haiyan in the Philippines, the Japan tsunami, the Haiti earthquake, the hunger crisis in the Horn of Africa, and the Indian Ocean tsunami.
Our seasoned emergency responders work through conflict in Gaza and are on the ground in Ukraine, Iraq, South Sudan and the Central African Republic distributing critical supplies and protecting families uprooted by ongoing violence.
We're also working to support nearly 4 million people affected by the crisis in Syria, a long-term refugee crisis and humanitarian disaster with no end in sight. Learn more about our ongoing response to the Syrian crisis ▸
All stories about Emergency response
Japan: What's buzzing in Japan
I added a new word in my Japanese vocabulary today: hae, which is the word for that common insect, the fly. In the tsunami-affected area of Japan, flies are now everywhere.
Indonesia: Pushing back the sea
Indonesia: A video blog from Indonesia's remote Mentawai Islands
Japan: A hot, hot summer
When I left Japan a little over a month ago, people warned me about what it would be like when I returned.
Somalia: Will the U.S. stand by as famine looms in Somalia?
"The drought has gotten so bad that we have seen camels dying of thirst," recounted a Mercy Corps colleague during my recent visit to Somalia.
Somalia: Reports of people moving north to find food as Somalia's drought conditions worsen
People affected by drought, conflict and limited access to humanitarian aid in Bay, Bakool, Lower and Middle Shabelle, Lower and Middle Juba, and Gedo regions of southern Somalia are fleeing north to find food and a better life.
Japan: The best octopus fisherman in town
Japan: For survivors like Sumiko, more than a bus ride
Japan: Moving day in Rikuzentakata
Rikuzentakata, Japan — When her home in this coastal city was destroyed by the tsunami, Tomoko Kinno, a 60-something retiree, was forced to stay with relatives hours away from here. She had lived with and cared for mother, who now had to stay in a temporary facility for the elderly.
Japan: When your hometown no longer looks like a town
As we head west toward the coast, and start to see signs of the March tsunami's devastation, I ask my colleague Sachie Saijo to stop the car so I can check it out.


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Chris Brown Drops 30pts at the Power106 Celebrity Basketball Game Last modified: September 21, 2015 at 4:23 pm Posts this month Like Print Page 2015 Posted On September 21 Written By staff Leave A Comment no comment Chris Brown Drops 30pts at the Power106 Celebrity Basketball Game Chris Brown scores 30 points at the Power106 Game benefitting Homeboy Industries. Other celebrities in the game were Nelly, Romeo Miller, French Montana, Kalin, Sage the Gemini, and others. Share Post Twitter Facebook Google+ Pinterest staff Post navigation Is Vanessa Bryant a Gold Digger? Player Rubs Icy-hot Mixture in Another Players Face During Game Comments Cancel reply Your email address will not be published. Name/Email fields are required * Name Email Website Comment You may use these HTML tags and attributes:  <acronym title="">
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text: 258 AWUS83 KPAH 060952 RWSPAH ILZ075>078-080>094-INZ081-082-085>088-KYZ001>022-MOZ076-086-087- 100-107>112-114-062200- WEATHER SUMMARY NATIONAL WEATHER SERVICE PADUCAH KY 352 AM CST SAT FEB 6 2016 Skies were clear to partly cloud overnight. It was chilly with predawn temperatures running in the 20s to near 30. High pressure will make for a relatively warm and dry weekend with a mix of sunshine and some clouds at times. South winds will bring a slight warm up until Sunday with highs in the low to mid 50s Saturday and Sunday. The passage of a strong cold front Sunday night will result in much colder temperatures during the first half of the next week with highs only in the 20s to mid 30s. This front and its associated upper level disturbance will bring a chance of light snow or flurries Monday into Tuesday, mainly along and east of the Mississippi River. && FOR A MORE DETAILED METEOROLOGICAL DISCUSSION, PLEASE REFER TO THE AREA FORECAST DISCUSSION PRODUCT (PIL SDFAFDPAH). $$


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Publications (33)200.17 Total impact
Article: The role of Cochrane reviews in informing international guidelines: a case study of using the Grading of Recommendations, Assessment, Development and Evaluation system to develop World Health Organization guidelines for the psychosocially assisted pharmac: Cochrane and GRADE for addiction guidelines[Show abstract] [Hide abstract]
ABSTRACT: The World Health Organization (WHO), and a growing number of other organizations, have adopted the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system in order to both assess the quality of research evidence and develop clinical practice guidelines. In 2009 WHO published a guideline on psychosocially assisted pharmacological treatment of opioid dependence, based on the results of Cochrane Reviews summarized using the GRADE methodology. The main features of this system are an a priori definition of outcomes and their relevance, and distinction between the quality of evidence (also referred to as confidence in the estimate of intervention effect) and the strength of recommendations. We consider how successful this approach has been. We discuss the merits and limitations of using Cochrane Reviews and GRADE framework in developing guidelines in the field of drug addiction. In 2009 a panel of multi-disciplinary international experts identified 15 clinical questions and eight relevant outcomes. Cochrane reviews were available for each clinical question and four outcomes. The panel formulated 15 recommendations. Eight recommendations were classified as strong, two of which were based on high-quality evidence and three on very low-quality evidence. For example, the strong recommendation to use methadone in adequate doses in preference to buprenorphine was based on high-quality evidence, while the strong recommendation not to use the combination of opioid antagonists with heavy sedation in the management of opioid withdrawal was based on low-quality evidence. An explicit stepwise process of moving from evaluation of the quality of evidence to the definition of the strength of recommendations is important in providing practical and clear clinical guidance for practitioners and policy-makers in addiction. © 2014 Society for the Study of Addiction.
Article: Expanding Disease Definitions in Guidelines and Expert Panel Ties to Industry: A Cross-sectional Study of Common Conditions in the United States[Show abstract] [Hide abstract]
ABSTRACT: Financial ties between health professionals and industry may unduly influence professional judgments and some researchers have suggested that widening disease definitions may be one driver of over-diagnosis, bringing potentially unnecessary labeling and harm. We aimed to identify guidelines in which disease definitions were changed, to assess whether any proposed changes would increase the numbers of individuals considered to have the disease, whether potential harms of expanding disease definitions were investigated, and the extent of members' industry ties.
Article: Developing and Evaluating Communication Strategies to Support Informed Decisions and Practice Based on Evidence (DECIDE): protocol and preliminary results[Show abstract] [Hide abstract]
ABSTRACT: Background Healthcare decision makers face challenges when using guidelines, including understanding the quality of the evidence or the values and preferences upon which recommendations are made, which are often not clear. Methods GRADE is a systematic approach towards assessing the quality of evidence and the strength of recommendations in healthcare. GRADE also gives advice on how to go from evidence to decisions. It has been developed to address the weaknesses of other grading systems and is now widely used internationally. The Developing and Evaluating Communication Strategies to Support Informed Decisions and Practice Based on Evidence (DECIDE) consortium (http://www.decide-collaboration.eu/), which includes members of the GRADE Working Group and other partners, will explore methods to ensure effective communication of evidence-based recommendations targeted at key stakeholders: healthcare professionals, policymakers, and managers, as well as patients and the general public. Surveys and interviews with guideline producers and other stakeholders will explore how presentation of the evidence could be improved to better meet their information needs. We will collect further stakeholder input from advisory groups, via consultations and user testing; this will be done across a wide range of healthcare systems in Europe, North America, and other countries. Targeted communication strategies will be developed, evaluated in randomized trials, refined, and assessed during the development of real guidelines. Discussion Results of the DECIDE project will improve the communication of evidence-based healthcare recommendations. Building on the work of the GRADE Working Group, DECIDE will develop and evaluate methods that address communication needs of guideline users. The project will produce strategies for communicating recommendations that have been rigorously evaluated in diverse settings, and it will support the transfer of research into practice in healthcare systems globally.
Article: Barriers and facilitators to the implementation of clinical practice guidelines: A cross-sectional survey among physicians in Estonia[Show abstract] [Hide abstract]
ABSTRACT: Background In an era when an increasing amount of clinical information is available to health care professionals, the effective implementation of clinical practice guidelines requires the development of strategies to facilitate the use of these guidelines. The objective of this study was to assess attitudes towards clinical practice guidelines, as well as the barriers and facilitators to their use, among Estonian physicians. The study was conducted to inform the revision of the clinical practice guideline development process and can provide inspiration to other countries considering the increasing use of evidence-based medicine. Methods We conducted an online survey of physicians to assess resource, system, and attitudinal barriers. We also asked a set of questions related to improving the use of clinical practice guidelines and collected free-text comments. We hypothesized that attitudes concerning guidelines may differ by gender, years of experience and practice setting. The study population consisted of physicians from the database of the Department of Continuing Medical Education of the University of Tartu. Differences between groups were analyzed using the Kruskal-Wallis non-parametric test. Results 41% (497/1212) of physicians in the database completed the questionnaire, comprising more than 10% of physicians in the country. Most respondents (79%) used treatment guidelines in their daily clinical practice. Lack of time was the barrier identified by the most physicians (42%), followed by lack of medical resources for implementation (32%). The majority of physicians disagreed with the statement that guidelines were not accessible (73%) or too complicated (70%). Physicians practicing in outpatient settings or for more than 25 years were the most likely to experience difficulties in guideline use. 95% of respondents agreed that an easy-to-find online database of guidelines would facilitate use. Conclusions Use of updated evidence-based guidelines is a prerequisite for the high-quality management of diseases, and recognizing the factors that affect guideline compliance makes it possible to work towards improving guideline adherence in clinical practice. In our study, physicians with long-term clinical experience and doctors in outpatient settings perceived more barriers, which should be taken into account when planning strategies in improving the use of guidelines. Informed by the results of the survey, leading health authorities are making an effort to develop specially designed interventions to implement clinical practice guidelines, including an easily accessible online database.
Article: Moving from Evidence to Developing Recommendations in Guidelines: Article 11 in Integrating and Coordinating Efforts in COPD Guideline Development. An Official ATS/ERS Workshop Report.[Show abstract] [Hide abstract]
ABSTRACT: INTRODUCTION: Professional societies, like many other organizations around the world, have recognized the need to use more rigorous processes to ensure that healthcare recommendations are informed by the best available research evidence. This is the 11th of a series of 14 articles that methodologists and researchers from around the world prepared to advise guideline developers for respiratory and other diseases on how to achieve this goal. For this article, we developed five key questions and updated a review of the literature on moving from evidence to recommendations. METHODS: We addressed the following specific questions.What is the strength of a recommendation and what determines the strength? What are the implications of strong and weak recommendations for patients, clinicians, and policy makers? Should guideline panels make recommendations in the face of very low-quality evidence? Under which circumstances should guideline panels make research recommendations? How should recommendations be formulated and presented? We searched PubMed and other databases of methodological studies for existing systematic reviews and relevant methodological research. We did not conduct systematic reviews ourselves. Our conclusions are based on available evidence, consideration of what guideline developers are doing, and pre- and postworkshop discussions. RESULTS AND DISCUSSION: The strength of a recommendation reflects the extent to which guideline developers can, across the range of patients for whom the recommendations are intended, be confident that the desirable effects of following the recommendation outweigh the undesirable effects. Four factors influence the strength of a recommendation: the quality of evidence supporting the recommendation, the balance between desirable and undesirable effects, the uncertainty or variability of patient values and preferences, and costs. Strong and weak (also called "conditional") recommendations have distinct implications for patients, clinicians, and policy makers. Adherence to strong recommendations or, in the case of weak (conditional) recommendations, documentation of discussion or shared decision making with a patient, might be used as quality measures or performance indicators. Clinicians desire guidance regardless of the quality of the underlying evidence. Very low-quality evidence should ideally result in either appropriately labeled recommendations (i.e., as based on very low-quality evidence) or a statement that the guideline panel did not reach consensus on the recommendation due to the lack of confidence in the effect estimates. However, guideline panels often have more resources, time, and information than practicing clinicians. Therefore, they may be in a position to use their best judgments to make recommendations even when there is very low-quality evidence, although some guideline developers disagree with this approach and prefer a general approach of not making recommendations in the face of very low-quality evidence. Guideline panels should consider making research recommendations when there is important uncertainty about the desirable and undesirable effects of an intervention, further research could reduce that uncertainty, and the potential benefits and savings of reducing the uncertainty outweigh the potential harms of not making the research recommendation. Recommendations for additional research should be as precise and specific as possible.
Article: The updated clinical guideline development process in Estonia is an efficient method for developing evidence-based guidelines[Show abstract] [Hide abstract]
ABSTRACT: Clinical practice guidelines are one of the tools available to improve the quality of health care. However, it may be difficult for countries to develop their own national guidelines "from scratch" because of limitations in time, expertise, and financial resources. The Estonian Health Insurance Fund (EHIF), in collaboration with other stakeholders, has launched a national effort to develop and implement evidence-based clinical practice guidelines aimed at improving the quality of care. Although the first EHIF handbook for preparing guidelines was published in 2004, there has been wide variation in the format and quality of guidelines prepared by medical specialty societies, EHIF, and other organizations in Estonia. An additional challenge to guideline development in Estonia is that it is a country with limited human resources. Therefore, revision of the Estonian guideline process was aimed at developing an efficient method for adapting current high-quality guidelines to the Estonian setting without compromising their quality. In 2010, a comprehensive assessment of guideline development in Estonia was made by the World Health Organization, EHIF, the Medical Faculty at the University of Tartu, and selected national and international experts in an effort to streamline and harmonize the principles and processes of guideline development in Estonia. This study summarizes the evaluation of and revisions to the process. Estonia has made substantial changes in its processes of clinical practice guideline development and implementation as part of an overall program aiming for systematic quality improvement in health care. This experience may be relevant to other small or resource-limited countries.
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ABSTRACT: Objectives: In this article, we describe how to include considerations about resource utilization when making recommendations according to the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. Study design and settings: We focus on challenges with rating the confidence in effect estimates (quality of evidence) and incorporating resource use into evidence profiles and Summary of Findings (SoF) tables. Results: GRADE recommends that important differences in resource use between alternative management strategies should be included along with other important outcomes in the evidence profile and SoF table. Key steps in considering resources in making recommendations with GRADE are the identification of items of resource use that may differ between alternative management strategies and that are potentially important to decision makers, finding evidence for the differences in resource use, making judgments regarding confidence in effect estimates using the same criteria used for health outcomes, and valuing the resource use in terms of costs for the specific setting for which recommendations are being made. Conclusions: With our framework, decision makers will have access to concise summaries of recommendations, including ratings of the quality of economic evidence, and better understand the implications for clinical decision making.
Article: Priority Medicines for Maternal and Child Health: A Global Survey of National Essential Medicines Lists[Show abstract] [Hide abstract]
ABSTRACT: In April 2011, the World Health Organization (WHO) published a list of "priority medicines" for maternal and child health based on 1) the global burden of disease and 2) evidence of efficacy and safety. The objective of this study was to examine the occurrence of these priority medicines on national essential medicines lists. All essential medicines lists published since 1999 were selected from the WHO website collection. The most-up-to date list for each country was then selected, resulting in 89 unique country lists. Each list was evaluated for inclusion of medicines (chemical entity, concentration, and dosage form) on the Priority Medicines List. There was global variation in the listing of the Priority Medicines. The most frequently listed medicine was paracetamol, on 94% (84/89) of lists. Sodium chloride, gentamicin and oral rehydration solution were on 93% (83/89) of lists. The least frequently listed medicine was the children's antimalarial rectal artesunate, on 8% of lists (7/89); artesunate injection was on 16% (14/89) of lists. Pediatric artemisinin combination therapy, as dispersible tablets or flexible oral solid dosage form, appeared on 36% (32/89) of lists. Procaine benzylpenicillin, for treatment of pediatric pneumonia and neonatal sepsis, was on 50% (45/89) of the lists. Zinc, for treatment of diarrhoea in children, was included on only 15% (13/89) of lists. For prevention and treatment of postpartum hemorrhage in women, oxytocin was more prevalent on the lists than misoprostol; they were included on 55 (62%) and 31 (35%) of lists, respectively. Cefixime, for treatment of uncomplicated anogenital gonococcal infection in woman was on 26% (23/89) of lists. Magnesium sulfate injection for treatment of severe pre-eclampsia and eclampsia was on 50% (45/89) of the lists. The findings suggest that countries need to urgently amend their lists to provide all priority medicines as part of the efforts to improve maternal and child health.
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ABSTRACT: This article describes how the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to grading the quality of evidence and strength of recommendations considers the Bradford Hill criteria for causation and how GRADE may relate to questions in public health. A primary concern in public health is that evidence from non-randomised studies may provide a more adequate or best available measure of a public health strategy's impact, but that such evidence might be graded as lower quality in the GRADE framework. GRADE, however, presents a framework that describes both criteria for assessing the quality of research evidence and the strength of recommendations that includes considerations arising from the Bradford Hill criteria. GRADE places emphasis on recommendations and in assessing quality of evidence; GRADE notes that randomisation is only one of many relevant factors. This article describes how causation may relate to developing recommendations and how the Bradford Hill criteria are considered in GRADE, using examples from the public health literature with a focus on immunisation.
Article: To give is better than to receive: Compliance with WHO guidelines for drug donations during 2000-2008[Show abstract] [Hide abstract]
ABSTRACT: to assess drug donations in terms of their adherence to the drug donation guidelines put forth by the World Health Organization (WHO). in 2009 we searched the academic and lay literature - journal articles, media articles and industry and donor web sites - to identify reports about drug donations made from 2000 to 2008. Publications focusing on molecular mechanisms of drug action, general descriptions of guidelines or specific one-time drug donations before 2000 were excluded. For cases with sufficient information, we assessed compliance with each of the 12 articles of WHO's guidelines. we found 95 articles describing 96 incidents of drug donations between 2000 and 2008. Of these, 50 were made in response to disaster situations, 43 involved the long-term donation of a drug to treat a specific disease and 3 were drug recycling cases. Disaster-related donations were less likely to comply with the guidelines, particularly in terms of meeting the recipient's needs, quality assurance and shelf-life, packaging and labelling, and information management. Recipient countries were burdened with the costs of destroying the drugs received through inappropriate donations. Although long-term donations were more likely to comply with WHO guidelines related to quality assurance and labelling, they did not consistently meet the needs of the recipients. Furthermore, they discouraged local drug production and development. drug donations can do more harm than good for the recipient countries. Strengthening the structures and systems for coordinating and monitoring drug donations and ensuring that these are driven by recipient needs will improve adherence to the drug donation guidelines set forth by WHO.
Article: Challenges in Developing Evidence-Based Recommendations Using the GRADE Approach: The Case of Mental, Neurological, and Substance Use Disorders[Show abstract] [Hide abstract]
ABSTRACT: GRADE is an approach for creating clinical practice guidelines based on an explicit assessment of the evidence base. GRADE is not a system for performing systematic reviews and meta-analyses (it is not a systematic review tool as, for example, the RevMan software of the Cochrane Collaboration at http://www.cc-ims.net/revman). The GRADE approach is suitable for (a) summarizing the evidence extracted from systematic reviews and meta-analyses into "Summary of Findings (SoF) tables"; (b) grading the quality of evidence summarized in SoF tables; and (c) grading the strength of treatment recommendations. GRADE separates the judgment on quality of evidence from strength of recommendations. An application called GRADE Profiler (GRADEpro) has been developed to summarize the evidence and grade its quality. GRADEpro can be freely downloaded at http://www.gradeworkinggroup.org/toolbox/index.htm. Additional information on the GRADE methodology and on the GRADE working group can be found at http://www.gradeworkinggroup.org/index.htm.
Article: Consort 2010
Chapter: Interpreting Clinical Evidence
- [Show abstract] [Hide abstract]
ABSTRACT: health policy;world health organization;pharmaceuticals;clinical trials;health insurance
Article: What Drives Health-Care Spending Priorities? An International Survey of Health-Care Professionals[Show abstract] [Hide abstract]
ABSTRACT: The authors set out to compare spending priorities for health care, across a selection of largely middle-income countries, through a survey of current and future decision makers.
Article: What drives health-care spending priorities?: an international survey of health-care professionals| NOVA. The University of Newcastle's Digital Repository
Article: Ties That Bind[Show abstract] [Hide abstract]
ABSTRACT: It is believed that pharmaceutical industry sponsorship of clinical research leads to the development of multiple ties between clinicians and the pharmaceutical industry. To quantify this relationship we conducted a survey of medical specialists listed in the Medical Directory of Australia in 2002 and 2003. A questionnaire was mailed that elicited information about all aspects of research relationships between clinicians and pharmaceutical companies. The odds of reporting multiple additional ties (financial and professional) with pharmaceutical companies by clinicians who had an active research relationship were compared with those who did not. All clinicians who returned a completed questionnaire about their research activities were included in the study. A questionnaire was mailed to 2120 medical specialists; 823 (39%) responded. Of these, 338 (41%) reported involvement in industry-sponsored research in the previous year. They were more likely than others to have been offered industry-sponsored items or activities valued at more than 500 AU dollars (>382 US dollars; odds ratio [OR], 3.5; 95% confidence interval [CI], 2.6-4.7) and support for attending international conferences (OR, 5.4; 95% CI, 3.9-7.4). The strongest associations were seen for acting as a paid consultant to industry (OR, 9.0; 95% CI, 3.9-20.4) and for membership on advisory boards (OR, 6.9; 95% CI, 5.1-9.6). There was a strong relationship between research collaboration and accumulation of industry ties. For 1 additional tie the OR was 2.2 (95% CI, 1.2-3.8) and rose to 6.3 (95% CI, 3.5-11.1) with 3 ties and 41.8 (95% CI, 14.5-143.4) with 6 or more ties. Medical specialists who have research relationships with the pharmaceutical industry are much more likely to have multiple additional ties than those who do not have research relationships. Institutional review should discourage clinical researchers from developing multiple ties.
Article: GRADE Working Group: Systems for grading the quality of evidence and the strength of recommendations II: Pilot study of a new system[Show abstract] [Hide abstract]
ABSTRACT: Systems that are used by different organisations to grade the quality of evidence and the strength of recommendations vary. They have different strengths and weaknesses. The GRADE Working Group has developed an approach that addresses key shortcomings in these systems. The aim of this study was to pilot test and further develop the GRADE approach to grading evidence and recommendations. A GRADE evidence profile consists of two tables: a quality assessment and a summary of findings. Twelve evidence profiles were used in this pilot study. Each evidence profile was made based on information available in a systematic review. Seventeen people were given instructions and independently graded the level of evidence and strength of recommendation for each of the 12 evidence profiles. For each example judgements were collected, summarised and discussed in the group with the aim of improving the proposed grading system. Kappas were calculated as a measure of chance-corrected agreement for the quality of evidence for each outcome for each of the twelve evidence profiles. The seventeen judges were also asked about the ease of understanding and the sensibility of the approach. All of the judgements were recorded and disagreements discussed. There was a varied amount of agreement on the quality of evidence for the outcomes relating to each of the twelve questions (kappa coefficients for agreement beyond chance ranged from 0 to 0.82). However, there was fair agreement about the relative importance of each outcome. There was poor agreement about the balance of benefits and harms and recommendations. Most of the disagreements were easily resolved through discussion. In general we found the GRADE approach to be clear, understandable and sensible. Some modifications were made in the approach and it was agreed that more information was needed in the evidence profiles. Judgements about evidence and recommendations are complex. Some subjectivity, especially regarding recommendations, is unavoidable. We believe our system for guiding these complex judgements appropriately balances the need for simplicity with the need for full and transparent consideration of all important issues.
Top Journals
University of Melbourne
Melbourne, Victoria, Australia
- Department of Medicine
Australian National UniversityCanberra, Australian Capital Territory, Australia
World Health Organization WHOGenève, Geneva, Switzerland
University of Newcastle
Newcastle, New South Wales, Australia
- Discipline of Clinical Pharmacology and Clinical Toxicology
Newcastle UniversityNewcastle-on-Tyne, England, United Kingdom


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You can download the latest release of Performance Analyzer 1.16 for Microsoft Dynamics at the following: http://dynamicsperf.codeplex.com.
This release officially supports SQL Server 2012 and all currently released Dynamics Products. There have been several performance improvements incorporated into this version especially around analyzing QUERY data. For the operational staff, we have enhanced the QUICK ACTIVITY MONITOR query to display all currently executing SQL statements, all current blocks, and open database cursors that have run in the last minute. Also included in this release, are the sample SSRS reports, which you will find located in the REPORTS folder when you unzip the project.
We have made a change in how we purge data from the database in this release. We will keep the last data collection per SQL Server restart regardless of @PURGE_DAYS. This will allow for long term analysis of Query and Index usage over time. You will be able to compare Query data before and after a patch to your SQL Server as an example. You will be able to determine if that index has ever been used vs. today where you can only see if it has been used since your last SQL restart.
There are many exciting things that we will be adding in the next version of Performance Analyzer that I will be sharing with you over the next several months. So, please stay tuned to the Blog for new and exciting features coming to your favorite performance tool for your Microsoft Dynamics product.
I will be presenting Performance Analyzer at Convergence this year. I'll be presenting on Wed. Mar. 20, 2013 at 5pm and Thur. Mar. 21, 2013 at 4pm. Please stop by and say hello if you are attending Convergence 2013. The session is named "Maximizing SQL Performance for Microsoft Dynamics".
Rod 'Hotrod' Hansen
Rod, the Deployment & User Guide seems very much geared at an AX installation (comments about AOS servers, AX tracing settings, DynamicsPerf database, etc). I would like to see you include documentation for each Dynamics platform which would make sense to the Administrator of another product.
See you at Convergence!
Thanks for the suggestion. I'll look into splitting that into 2 documents. One for the Core and one for Dynamics AX which is the only product that we have custom steps for at the moment.
We have corrected an issue where you may only have 2 records in the QUERY_STATS_CURR_VW. This was caused by an XML processing error. Send an email to email@example.com requesting the query_plans fix and I'll send you the updated stored procedure. The download site will have a new file dated after Mar. 11, 2013 shortly with the fix in it.
Hi Rod
Is dynamicsperf 1.0 available online? I am trying to work on a SQL Server 2005 database and the oldest version I can find is 1.15.
Thanks, Daniel.
Rod: Does a document regarding the typical workload of a Dynamics AX implementation exist? I am working with a lot of customers implementing Dynamics AX and want to size disks for the solution. Exchange has a calculator to determine megacycles, RAM requirements, and the read/write split and block size is widely advertised.
Does such an animal exist for Dynamics AX?


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After being imprisoned for 20 years, Zorro -- Don Diego de la Vega -- receives word that his old enemy, Don Rafael Montero, has returned. Don Diego escapes and returns to his old headquarters, where he trains aimless drunk Alejandro Murrieta to be his successor. Meanwhile, Montero -- who has secretly raised Diego's daughter, Elena, as his own -- hatches a plot to rob California of its gold.
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- The subtle lines of the curving metal adapt it into a modern setting; whereas its sinuous shape also makes it compatible with Art Deco.
- This lamp can stand in a corner and light up a high room, or you can place it behind a couch for a more intimate effect.
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Meet the top three Tech All Stars 2015 at Capital On Stage London
Tech All Stars is part of Startup Europe, the Commission's plan to accelerate, connect and celebrate local entrepreneurship ecosystems in Europe, so as to keep startups in Europe. The top 12 were from the UK, Belgium, Germany, Italy, the Netherlands, Portugal, and Sweden. Tech All Stars brings together startup founders to give them valuable training while taking them to the best startup events including Capital On Stage.
On London June 30, meet the three founders and find out why there were crowned the best in Europe:
TripRebel: Carlos Borges, CEO
TripRebel is the "rebel" in travel booking websites and the concept is simple: book your hotel through the site, which currently lists more than 200,000 properties around the world. It then tracks your reservation for price reductions every day until you check in. If the price drops, you'll be automatically re-booked at the new rate, and the difference is refunded to your credit card.
Winnow: Marc Zornes, CEO
Winnow's mission is to help the hospitality industry cut down on food waste by making the kitchen 'smarter.' It does this via the Winnow smart meter, a set of smart scales and accompanying tablet app that lets kitchen staff easily log what food is thrown away. That data is then uploaded to the cloud, analysed by Winnow's algorithm, and disseminated so that food waste can be reduced.
Watly: Marco Attisani, WEO
We create technological solutions powered by clean and renewable energies. They respect and protect the Earth's ecosystem. They are conceived through innovative design and unconventional engineering approach. We are inspired by the 3rd Industrial Revolu-tion paradigms and its potential.
November, the Tech All Stars they will take to the stage again at NOAH London to show their progress five months after this enormous investor attention.
We are very privileged to have these talented pitch winners joining us at Capital On Stage. Let's see how they go bringing their pitch from 3 min to 30 seconds.
5 Ways To Convince A Growth Stage Startup To Take Your Money
Now that anyone can benefit from the global growth of entrepreneurial activity, venture capitalists need to show their true added value more than ever – their added value besides the offering of cash.
Sharon Vosmek, Astia: Exclusive Interview with Capital On Stage
(by Charles Blass, 22 October 2014)
6 Reasons Your Startup Should Apply for Capital On Stage NYC
The unconventional conference is coming to Orrick NYC on Oct 30. 200 carefully curated venture capital (VC) firms and growth stage startups will connect.
Andrew Cleland, Comcast Ventures: Exclusive Interview with Capital On Stage
Andrew Cleland, Comcast Ventures: Exclusive Interview with Capital On Stage
(by Charles Blass, 17 October 2014)
(COS: On behalf of Capital On Stage, we appreciate the opportunity to gain some insight in advance of the event. We wanted to learn more about you as an individual, beyond your firm and its objectives. So, how did you get to where you are now and what were you doing before investing? Please tell us about your trajectory.)
How To Pitch An Entrepreneur And Persuade Her To Take Your Cash
With the rise of a trillion-dollar crowdfunding market, angel investors bundling their investment offerings, and family offices doing more direct investments, venture capitalists are no longer the only available source for entrepreneurs seeking funding. Now that anyone can benefit from the global growth of entrepreneurial activity, venture capitalists need to show their true added value more than ever, in order to attract the most capable entrepreneurs.
VCs pitching to entrepreneurs - how well do they connect?
Venture Capital or Corporate Venture Capital - what's the relevance?
Just like any product, there are features and benefits that are more relevant to particular target groups, at particular times. The same can be said for venture capital and corporate venture capital, yet there are some strong views out there, implying one is always better than another. In my opinion, investment deals should be viewed ...
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Open Office Hours - Opens Tomorrow
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Give a big COS welcome to John Stokes and Charlie O'Donnell, who will be joining the stage at Goodwin Procter next Thursday (Nov 7) for the second edition of Capital on Stage New York.
Gender Diversity at Capital on Stage New York
With four women confirmed to speak, Capital on Stage is proud to announce that our New York events have the highest representation of women on stage than any of our other conferences.
It is always hard to find women to welcome on stage; not because they don't want to pitch, quite the contrary, it ...
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Iron Man 2 (2010) Music Video - Shoot to Thrill
Music video for Iron Man 2 features the track "Shoot to Thrill" by AC/DC. Clip mixes scenes from the film with footage from a live performance by the band in Argentina. Video courtesy of The Sun.
Film Info
5 min 28 sec Duration
124,587 views
- Posted: January 26, 2010
- Director: Jon Favreau
- Writer: Justin Theroux
- Studio: Paramount Pictures
- Release: May 7, 2010
- Cast: Robert Downey Jr., Gwyneth Paltrow, Don Cheadle
Trailer Tracks
No music available


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Alumni Relations
Blocking stress protein relieves chronic pain in mice
Published: Feb 11, 2016 9:20:19 AM
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Published: Jan 29, 2016 10:02:47 AM
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Published: Jan 27, 2016 11:09:18 AM
You can contact the alumni volunteers below to find out about their experiences of studying at UCL. They may also be able to put you in contact with other UCL alumni in their region.
For general enquiries regarding Alumni Contacts in Africa please contact:
Natalia Mazzini-Cea - Alumni Relations Officer - International
- Momodou Lamin Sompo Ceesay (UCL Chemical Engineering, 2001)
- Kingsford Laryea (UCL Architecture 1992)
- James Annkah (UCL Medical Physics 2006)
- Dr Olufunmilola Ogun (UCL Medical School 2007)
- Olapeju Adenuga (UCL Laws 2006)
- Amro A. Hussien (UCL Nanotechnology and Regenerative Medicine, 2012)
There are a number of volunteer-led UCL alumni groups in operation throughout Asia. You can find further information using the links below. Where a group structure doesn't exist, you will often find an alumni volunteer to make contact with.
For general enquiries regarding alumni activity in Asia please contact:
Alexandra Broekema - Senior Alumni Relations Manager - International
for China and Hong Kong
Natalia Mazzini-Cea - Alumni Relations Officer - International
for Cambodia, India, Japan, Kazakhstan, Korea, Malaysia, Pakistan, Philippines, Singapore, Sri Lanka, Taiwan and Thailand.
- Beijing - Alumni Contact: Hiu Ng (UCL SLAIS, 2001) or for general queries: Frank Guan (UCL Economics 2010)
- Guangzhou - Alumni Contact: Shu Alex Chen (UCL Economics 2007)
- UCL Shanghai Alumni Group
- Shanghai - Alumni Contacts: Stella Lu (UCL Laws 2011) and Deming Zhao (UCL Laws 1999)
- Shenzhen - Alumni Contact: Yusen Wang (UCL Economics 2010)
- Xi'an- Alumni Contact: Wenjie Lu (UCL Laws LLM, 2013)
Hong Kong
- UCL Hong Kong Club
- Chairman: Mr Andrew Ng (UCL Laws 1985)
- Student enquiries: Anna Ang (UCL Laws, 1999), Doris Chen (UCL History 2013)
- UCL Activities in India
- Delhi - Alumni Contact: Dr Kshitij Malik (UCL Ear Institute 2007), Anubhuti Agrawal (UCL Laws 2009, Nishant Nigam (UCL Laws 2009)
- Mumbai - Dr Marcus Ranney (UCL Medical School 2008)
- UCL Japan Club
- President: Yutaka Kikugawa (UCL Geography 1995), Enquiries: Takashi Watanabe (UCL Laws 2007)
- Alumni Contact: Almas Kudaibergen (UCL Public Policy 2004)
- UCL Alumni Association Korea
- President: Dr Wookyung Lee (UCL Electronic & Electrical Engineering PhD 1999)
- Alumni events in Malaysia
- Alumni Contacts: Cyril Natarajan (UCL Medical School, 2005), Lin Yow Chen (UCL Electrical Engineering 2003)
- Karachi- Alumni contact: Dabeera Azra Yaqub (UCL Bartlet School 1991)
- Lahore- Alumni contact: Madiha Latif (UCL Management Science and Innovation 2010)
- Alumni Contact: Andre Palacios (UCL Laws 2006)
- UCL Alumni Singapore (UCLAS)
- President: Dr Jack Lee (UCL Laws 2003), Vice President: Kailash Rai (UCL Human Sciences 2008)
Sri Lanka
- UCL Sri Lanka Alumni
- Alumni Contacts: Anushka Wijesinha (UCL Economics 2007), Dr Somasundaram Dharmavasan (UCL Civil Engineering, 1978) or Shelendra Nonis (UCL Laws 2000)
- UCL Taiwan Alumni Association
- President: Ying-Fong Chen (UCL Bartlett 2005)
- Alumni Contact: Charinee Senanarong (UCL Economics 2000) and Dr Boonjong Buranawatanachoke (UCL Biochemical Engineering 2008)
For general enquries regarding international alumni activity please contact:
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- Perth, Alumni Contact: Dr Pauline Sadler (Laws 1970)
- Sydney, Alumni Contact: Mr Justin Fleming (Laws 1991)
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For general enquires regarding alumni activity in Europe please contact:
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for France, Germany and Switzerland.
Natalia Mazzini-Cea - Alumni Relations Officer - International
for Austria, Belgium, Cyprus, Czech Republic, Finland, Greece, Hungary,
Italy, Norway, Portugal, Romania, Russia, Slovenia, Turkey and Ukraine.
- Alumni Contact: Andreas Hampl (UCL Development Planning Unit 2011)
- UCL alumni event in Brussels
- Alumni Contact: Jeroen Smets (UCL Laws 1997)
- UCL Cyprus Friends & Alumni Association
- Alumni Contacts: Christis Christodoulou (UCL Economics 1987), Savvas Savva (UCL Electronic Engineering 1993), Despo Pilides (UCL Ph.D. Archaeology 1979)
Czech Republic
- Alumni Contact: Jan Srutek (Human Computer Interaction 2009)
- UCL Alumni France Group
- Alumni Contacts: Julia McHugo (UCL SSEES 2010), Mr Bob Lewis (UCL Geography 1978)
- Berlin - Alumni Contacts: Mr Boris Preckwitz (UCL German 1995), Hannes Ansorg (UCL Economics 2013)
- Cologne/Dusseldorf - Alumni Contact: Mr Joerg Schulze (UCL German & Linguistics 1991)
- Hanover/Braunschweig - Alumni Contact: Mr Jonathan Haig (UCL Geological Sciences 2001)
- Munich - Alumni Contacts: Fabian Paul Eckert (UCL Economics 2013), Florian Liedl (UCL Laws 2013)
- UCL Alumni Greece Group
- Southern Greece Alumni Contacts: Dr Areti Mizara (UCL Geography 1993), Dr Ioannis Papanikolaou (UCL Geology 2003)
- Northern Greece Alumni Contact: Christos Karagiannidis (UCL SSEES 2002)
- Alumni Contact: Tamás Szabados (UCL Laws 2008)
- UCL Alumni Hungary Facebook page
- Alumni Contact: Emilio Cocco ( UCL SSEES 2000)
- Alumni Contact: Peter Bennett (UCL Psychology 1973)
- Alumni Contact: Juuso Turtiainen (UCL Laws 2015)
- UCL Alumni in Portugal
- Alumni Contacts: Maria Empis (UCL History of Art 1993) and Luis Roquette Geraldes (UCL Laws 2008)
- Alumni Contact: Bogdan Batrinca (UCL BSc Computer Science 2012, MRes Financial Computing 2013)
- Alumni Contact: Fiona Wood (UCL SSEES 2005)
- Facebook group for Swiss alumni
- Alumni Contacts: Martina Faherty (UCL History of Art 2001)
- Facebook for alumni in Turkey
- Alumni contact: Sinan Arslaner (UCL Economics 1983)
- Alumni Contact: Eduard Shestunov (UCL Bartlett 2013)
- Alumni contact: Nejc Novak (UCL Laws 2011)
Middle East
For general enquires regarding alumni activity in the Gulf states and elsewhere in the Middle East please contact:
Alexandra Broekema - Senior Alumni Relations Manager - International
for UAE (United Arab Emirates).
Natalia Mazzini-Cea - Alumni Relations Officer - International
for Egypt, Iraq, Israel, Jordan, Kuwait, Qatar, Saudi Arabia and Syria.
- Alumni Contact: Tamer El-Khouly (UCL Bartlett 2015)
- Alumni activity in Egypt
- Alumni Contact: Jennifer Janes (UCL Laws 1963)
- Alumni Activity in Israel
- Alumni Contact: Haydar Kamala (UCL Chemical Engineering 2010)
- Alumni Contact: Dr Zaid H. Baqain (UCL Eastman 2000)
- Alumni Contact: Hussain Al-Mosawy (UCL Mathematics, 2005)
- Alumni Contact: Sheikh Asif Mahmood (UCL Bartlett 2006)
- Alumni Contact: Sheikh Asif Mahmood (UCL Bartlett 2006)
- Alumni Activity in Qatar
Saudi Arabia
- Alumni Contacts: Mousa Al- Enezi (UCL Biochemical Engineering 2012) Adnan Rafiq (UCL Economics, 1995), Sultan Alshathry (UCL Bartlett 2010), Dr Najeeb Ghanem (UCL Pharmacology 1988)
- Alumni Activity in Saudi Arabia
- Alumni Contact: Rashad Kattan (UCL Political Science 2011)
United Arab Emirates
- Alumni Contacts: Joseph Tabarani (UCL Economics 2007) and Dr Baher Ashour (UCL Ear Institute, 2005)
To find out more about what alumni groups in the region are doing see the UCL Alumni Arabia Facebook page
North America
For general enquires regarding alumni activity in North America please contact:
Alexandra Broekema - Senior Alumni Relations Manager - International
for USA.
Natalia Mazzini-Cea - Alumni Relations Officer - International
for Canada, Mexico, Trinidad & Tobago.
Please do get in touch if you would like to set up an alumni group in your area, or have suggestions for venues, activities or speakers in your region.
- Toronto - Alumni Contact: Susan Stock (UCL Archaeology 1976)
- Toronto - Alumni Contact: Mark Trayling (UCL Economics)
- Ottawa - Alumni Contact: Gavin Nardocchio-Jones (UCL History 2004)
- Alumni Contacts: Yukiko Hosaka (UCL Computer Science, 2000) Isabel Lopez Estrada (UCL Political Science 2013)
- Connect with UCL Alumni in Mexico through the group's facebook page
Trinidad & Tobago
- Alumni Contact: Gino Soobratee (UCL Bartlett, 2006)
United States of America
- Alumni contacts: Southern California: Helen Talkin (UCL Scandinavian Studies 1984)
- Los Angeles: Jane Chamberlin (UCL French and German 1997), Jeffrey Nakamura (UCL Slade School of Fine Art 2006)
San Francisco Alumni Contact:
- Martin Poschenrieder (UCL Management Science & Innovation 2011)
- Alumni Contact: Dr Jonas Vibell (UCL Psychology 2002)
New York Club
- Alumni Contacts: Leonor White (UCL Civil, Environmental and Geomatic Engineering 2011) and Amanda Granek (UCL Slade School of Fine Art 2005)
- Alumni Contact: May Akrawi (UCL Biochemistry PhD 1995)
Washington DC
- Alumni Contacts: Alexis Lavi (UCL Political Science 2011) and Jerome Raymond (UCL Bartlett 2012)
Washington: To sign up search for 'UCL Washington D.C. Alumni' or click here.
Canada: To sign up search for 'UCL Alumni - Canada' or click here.
South America
For general enquires regarding alumni activity in South America please contact:
Natalia Mazzini-Cea - Alumni Relations Officer - International
- Alumni Contact: Simon C. Mikel Butron Heredia (UCL Entrepreneurship MSc 2008)
- Alumni Contact: Alex Makray (UCL Law 2013)
- Alumni Contact: (Sao Paulo): José Fernandes (UCL Development Planning Unit 2012)
- Alumni Contact: Luiz Carlos Chagas (UCL Development & Planning 2005)
- Alumni Contact: (Vitoria) Roberto Kuster (UCL Laws 2014)
- Alumni Contacts: Juan Poblete Poulsen (UCL Civil, Environmental and Geomatic Engineering 2011) and Felipe Corvalan Lagos (UCL Laws 2011)
- UCL activities in Chile
- Alumni Contact: Kely Sarmiento Eljadue (MSc Spatial Design: Architecture and Cities 2012)
- UCL activities in Colombia
- Alumni Contact: Rafael Paredes (LLM Law 2013)
- Alumni Contact: Humberto Zogbi (MSc Public Policy 2013)


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Clinical Trials →STM 434 is a soluble receptor fused to part of an antibody that is designed to block the growth factor Activin A. STM 434 is being studied in patients with ovarian cancer and other advanced solid tumors.
Ovarian Cancer
Ovarian cancer is a disease that worldwide leads to 125,000 deaths and is the fifth leading cause of cancer death in women in the United States. According to the National Cancer Institute, there were an estimated 22,240 new ovarian cancer cases and 14,030 ovarian cancer deaths in the United States in 2013. Surgery and cytotoxic chemotherapies are widely used to treat ovarian cancer; however, the outcomes have changed little in 40 years. The proportion of all ovarian cancer patients surviving five years after diagnosis was only 44% based on the National Cancer Institute SEER database for women diagnosed from 2003 to 2009. New therapies are needed to address this important issue in women's health. Importantly, the levels of the transforming growth factor Activin A are elevated in patients with ovarian cancer, making this molecule an attractive target for novel therapeutic approaches.
We are investigating whether STM 434 can change the course of ovarian tumor growth by blocking the action of Activin A. Preclinical studies demonstrated that Activin A inhibitors can reduce ovarian tumor growth, complement the benefits of concurrent chemotherapy and improve survival in mice.
Other Advanced Solid Tumors
We are also investigating STM 434 in several advanced solid tumors which are known to overexpress Activin A. For example, preclinical studies with a surrogate of STM 434 have demonstrated improved survival in a mouse model of colon cancer.
Mechanism of Action
STM 434 is a ligand trap, which mimics the ActR2B receptor, binding Activin A and other ligands (such as activin B made by kidney tumors) that would otherwise activate this receptor promoting tumor proliferation or invasion.
Preclinical results in experiments blocking Activin A by using a soluble receptor, both as a single therapy and in combination with chemotherapy, led to a reduction in tumor size. In other experiments, mice with high Activin A levels, which caused granulosa cell ovarian tumors, survived longer after treatment with a surrogate for STM 434 in comparison to untreated mice.
Lu J, Haqq CM, Han HQ. Effects of a soluble activin type 2B receptor Fc fusion protein (STM 217) in TOV-21G, a mouse xenograft model of clear cell ovarian cancer. J Clin Oncol 2013; 31 (supplement; abstract 2541). (Citation)
Zhou X, Wang JL, Lu J, Song Y, Kwak KS, Jiao Q, et al. Reversal of cancer cachexia and muscle wasting by ActRIIB antagonism leads to prolonged survival. Cell. 2010; 142(4):531-43. (Citation)


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Shaanxi Jintai Biological Engineering Co., Ltd.
Start Order
|Business Type:
|Manufacturer, Trading Company
|Main Products:
|Shaanxi, China (Mainland)
|Year Established:
|Year start exporting:
|Total Employees:
|11 - 50 People
|Total Annual Revenue:
|Main Markets:
|Average Lead Time:
|3 Day(s)
Shaanxi Jintai Biological Engineering Co., Ltd., Is the purification of active ingredients in plants processing high-tech ent...
Shaanxi Jintai Biological Engineering Co., Ltd., Is the purification of active ingredients
in plants processing high-tech enterprises. The company is integrate production, sales and service in one, plant extracts, active ingredients monomer, plant powder, natural Fruit& vegetable powde-oriented products, is committed to research and development of plant extracts production of professional companies.
Company consists of the market, R & D, production, marketing and other departments, R & D center has multiple high performance liquid chromatography, gas chromatography, magnetic drive autoclave and other advanced testing, experimental, pilot equipment; company has the plant extract workshop production line, and dynamic countercurrent extraction, column separation, membrane separation technology, efficient counter-current extraction, microwave drying, spray drying hormones and other advanced production equipment, strong technical force, annual production of 500 tons, product specifications, quality and stability.
The company has perfect quality assurance system of enterprises, the implementation of strict quality control standards. And passed the ISO9001 international quality system certification. Quality Management Division deployed a number of pieces (sets) gas, liquid, UV and other advanced testing and experimental equipment, and technology research, quality assurance and quality control division of the three functions of the details of the production process for effective and comprehensive quality control, ensuring product quality.
To provide users with the hight qulity product, is our consistent pursuit. Company has a strong team of experienced engineers and promising young management team, all staff adhering to the faith first, quality-oriented service concept, adherence to the "rigorous and realistic progressive unity" approach to high-quality products, reasonable prices, good service, won the trust of users. Kam Tai biological sincerely welcome your cooperation.
A Supplier Assessment Report provides verified information about a company's production and trade capabilities. This includes factors such as company legal status, human resources, export records, production capacity, quality assurance, customer service, production process management, R&D, certifications and more. View sample.
Company Capability
Trade Capacity
North America : 48.78%
Western Europe : 24.39%
Production Capacity
Factory Size : Below 1,000 square meters
No. of Production Lines : 2
R&D Capacity
No. of R&D Staff : 5 - 10 People
Email to this supplier