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Originally posted by Irish M1ck
Did anyone ever read what exactly killed her? I have searched many stories and haven't found anything yet.
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Erick Aybar
Sponsored By
When It Comes To Your Fantasy Team, Always Be Looking For Someone BetterAs you approach the end of the first month of the fantasy baseball season, like all smart fantasy owners you must look every day for better players. Sure, you may like a guy on your bench who plays for the local nine, but fantasy baseball is won with the head—not the heart.
Hartnett: Yankees Can Compete With Rebuilt AngelsDespite the big-name signings of Albert Pujols and C.J. Wilson, the Los Angeles Angels haven't distanced themselves from the 2012 Yankees.
Not A Nice Outing For Niese, Mets Lose 7-3The Mets lost their first series since dropping two of three to Philadelphia in late May.

subset: commoncrawl


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Combo Discount:
It does the job.
Posted by 5471593555204295832 on Jul 30, 2013
We bought this because it has cancer-free ingredients. It's a typical baby moisturizer. The pump design is useful. The vanilla almond scent is mild unlike the very fragrant Johnson & Johnson baby lotions. It's not greasy or too watery. It does exactly what it should do like a normal baby lotion (ie. not enriched moisturizer, etc.) . However, it does seem to irritate existing rashes from eczema or heat, etc.
Was this review helpful to you?
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Viewing Tattoo Tag: fire
My first one
Is Saint Uriel Archangel's representation. He's the fire of God and also is protector of spirituality and wisdom. I have it on my back's left side, just on my heart spot… because I want to he look after me for… [ read more ]11/25/13
I believe that the four elements together is what keeps the human race going. Take one away then its chaos04/02/13
My nickname is "Kittie" & I have a spitfire personality. The location is on the back of my thigh as I am a former track & field athlete.06/10/12
my first sleeve, my darker side sleeve,02/09/12
This is a tatoo of Good Vs. Evil. I also got it for my wife whom is nick named Devil Angel for the different ways she can act…10/28/10


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Payment Options
Tuition & Fees: Due Dates
- Summer Semester - May 25, 2015
- Fall Semester - August 10, 2015
- Spring Semester - January 4, 2016
Payment Options
Students may fulfill their tuition/fee cost responsibilities at Mid-State using the following payment methods:
- Cash
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- Check/Credit Card: Mid-State accepts Discover, MasterCard, or Visa. Both check and credit card payments are accepted online at MyMSTC.
- Installment Payment Plan: Students with a balance of $300 or more may participate in the Installment Payment Plan (IPP). Summer 2015 Semester, first installment due May 25, 2015, Fall 2015 Semester, first installment due August 10, 2015, and Spring 2016 Semester, first installment due January 4, 2016. A $25 fee is applied per semester to participate in the IPP. The $25 fee can be waived when automatic payments are set up upon enrollment into the IPP. Students are able to enroll in the payment plan online at MyMSTC.
- Financial Aid: Students attending Mid-State on financial aid must have a completed financial aid application by August 17 (fall semester) and January 11 (spring semester) to have their tuition and fees deferred. The Free Application for Federal Student Aid (FAFSA) must be processed with a valid Student Aid Report released to Mid-State to defer payment of tuition and fees until the financial aid award is accepted and financial aid funds can be credited to the account. If financial aid does not cover the entire amount owed to Mid-State, the student is responsible for the immediate payment of the balance. Students will be sent a monthly invoice until tuition and fees are paid in full.
- Agency/Employer Sponsorship: If financial assistance is provided on behalf of a student by an agency or an employer, written authorization from the sponsor must be on file by January 11 to allow the student to defer payment of tuition, fees and books (per the sponsor authorization).The sponsor will be billed directly for the authorized costs. If the sponsor does not cover the entire amount of the tuition/fee and fees, the student must choose from the other payment options for the remaining balance. Book costs may not be deferred unless covered by sponsorship.


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Welcome to WebmasterWorld Guest from 22.214.171.124
Forum Moderators: Robert Charlton & aakk9999 & brotherhood of lan & goodroi
[edited by: brotherhood_of_LAN at 8:50 pm (utc) on May 6, 2014]
[edit reason] changes to example. [/edit]
So... If you already removed the thin content, you have a big disavow tool and you did a lot of nofollow on insite links, than this is the next step.
Cut deep!


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Email Us
2915 Hannah Avenue
East Norriton, PA 19401
CrossFit is a core strength and conditioning program that delivers a fitness program that is by design: broad, general, and inclusive. Elements of track and field, gymnastics, Olympic weight lifting, and strongman are combined in short, intense, daily workouts to maximize RESULTS for any individual.
CrossFit teaches FUNCTIONAL movement patterns, or movements that you translate to real life - pushing, pulling, squatting, jumping, throwing, carrying, and sprinting. One of the best parts of CrossFit is COMMUNITY! You get to enjoy your workout and make friends doing it.The three owners of CrossFit MontCo can attest that being a part of the CrossFit community has IMPROVED their physical, mental and social wellness.
The CrossFit model can work for EVERYONE, ranging from the inexperienced, timid gym goer to the elite athlete.The beauty of our program model is that all movements can be SCALED and MODIFIED to the needs of the individual. If you don't believe us, drop in, watch a class and talk to one of our coaches!
CLICK HERE to visit our contact page to sign up.
OnRamp is designed to introduce the movements and workouts we do in CrossFit on a daily basis as well as introduce our coaches and facility. As such, it is important for you to attend the requisite OnRamp before attending the normal class. We are currently scheduling On Ramps on Saturdays and Sundays. Other accommodations can be made.
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- Find a rental
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White Rose Villa
From $99 / night
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Description from the owner
Description from the owner
Bedrooms: 4/
Bathrooms: 3/
Sleeps: 8/
Type: Villa
The 'White Rose Villa' is a single storey, 4 bedroom / 3 bathroom private villa.
Based on an award winning design it has everything you need for your sunshine vacation.
Being a single storey home, means that you never have to climb a long flight of stairs again, after a tiring day touring the theme parks! Also having no stairs makes the property easily accessible for the less able bodied.
For you and your family's safety, the villa is totally compliant with all fire and safety regulations. There are smoke alarms throughout, a handy fire extinguisher, and all doors leading to the swimming pool are lockable and alarmed. .
Bedrooms & Bathrooms: ...Read more
About the owner
About the owner
Dave R.
Dave R.
- Response rate : 100%
- Response time: A few hours
- Calendar updated: 10 days ago
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Additional Location Information
The "White Rose Villa" is situated in a quiet development at Bridgewater, in the suburb of Davenport, and is ideally situated for all the major attractions and amenities that Orlando has to offer.
The "White Rose" is only 10 minutes from the entrance to "Disney", 20 minutes from "Sea World", and 25 minutes from "Universal Studios". This gives it an ideal location as a base camp for your family holiday, and the perfect place to relax after a busy day around the theme parks.
Local amenities include a small shopping plaza with a large supermarket, drug store, Hairdressers, Bank, various food outlets and a family restaurant, all within 3 minutes drive of the villa.
The famous Highway 192 is only 10 minutes drive away, giving easy access to countless shops, supermarkets and restaurants.
There is the added bonus of being only 30 minutes from Orlando Airport, Less than an hour from Sanford Airport, and approximately 75 minutes drive to the East coast beaches and 90 minutes to the West coast beaches.
For all you golfers, there are over 50 top rated golf courses within 30 minutes drive, and over 150 within an hours drive. There are golf courses to cater for all standards of golfers and all depths of pockets!
Five minutes from an exit of I-4, places it in perfect position to explore the many wonderful sights that Florida has to offer!
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Lake nearby, Rural retreats, Waterfront
Getting There
Nearest airport: Orlando International, 25 miles
Car is essential
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Breaking News
Japan envoy visits China in bid for calm
- From: AAP
- January 22, 2013
A JAPANESE envoy has arrived in Beijing for talks aimed at cooling tensions over an island dispute.
Chinese media reported on Tuesday that Natsuo Yamaguchi was to deliver a letter from Japanese Prime Minister Shinzo Abe during his four-day visit.
In Tokyo, he told reporters he hoped his trip would help ease tensions and that consultations were needed to "normalise our relationship."
Yamaguchi heads the New Komeito party, the junior partner of Abe's ruling Liberal Democratic Party.
Tensions soared after Japan's government bought the uninhabited islands, known in Chinese as Diaoyu and Japanese as Senkaku, from their private owners in September.
Both sides scrambled jet fighters this month in the latest spike in tensions.


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What does PAEM stand for?
What does PAEM mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: PAEM.
We've found a total of 4 definitions for PAEM:
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Programa de Apoyo Empresarial a las Mujeres
Emmonak,USA - AK
Performance Assessment and Enhancement Management
Performance Assessment and Enhancement Management
Still can't find the acronym definition you were looking for? Use our Power Search technology to look for more unique definitions from across the web!
"PAEM." Abbreviations.com. STANDS4 LLC, 2016. Web. 14 Feb. 2016. <http://www.abbreviations.com/PAEM>.


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Very pretty
Reminds me of 'Frozen' (these would make awesome Elsa nails) or bubbles.
May I ask how you did that? 'cause it is very pretty and I would like to do that myself :3
I glad you like it! Sorry, i can not explain it in English. I think you understand how make this manicure here vk.com/topic-35612080_28017299
Pretty ^_^


text: I have created a page "Gallery" in my website. Where I have inserted the default wordpress gallery to display images. I want to add sexyboomarks button for each image in the gallery. At present sexybookmarks works only with posts of pages as a whole, but i'm talking about applying it for individual content in the page. Is it possible? If yes, can anybody please tell me how I can do it?


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Tags: dagfs, mistress, bondage, slave, domination, bdsm, torture, clothespin, Lesbian, dildo
Categories: Fetish, Hardcore, Lesbians
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Hot Lesbian bondage - The Mistress doesn't joke with her hot slave. She bit her neck and toyed her pussy with a huge dildo while she was tied up!


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Featured news
Easy steps can ensure that no one intercepts your Wi-Fi traffic
Almost all of us have jumped onto someone else's unsecured Wi-Fi network. There's little harm in that if you're just an honest soul looking for an Internet connection.
But if you're the owner of an unsecured network, you should be aware that the world's not made up entirely of honest souls--and it's not hard for the dishonest ones to see exactly what you're doing on your network. Sound scary? Here's how to fix the problem.
At eCoustics.
[ Read more ]
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Everyone will pound into your head one thing as you begin your career journey — network. Okay, we get it, but how exactly do I network? Surprisingly, it's more than clicking a few buttons on LinkedIn.
Put yourself out there and ask your coworker out for a midday coffee. Maybe strike up a conversation with the guy on the other side of the office from you that you bump into on the elevator. Do something more than the one time hello followed up by the instant LinkedIn request. Your network should exist outside of a computer screen and truly be your support both inside and outside of the workplace.
While large crowds at corporate networking events may not be your thing, the value of making face-to-face connections should always be in mind. By getting to know someone and forming that relationship can be a powerful tool. Sure, they could search their LinkedIn contacts for someone with experience in X, Y, or Z… Or you could be the person that jumps to their mind because of a conversation you had over lunch one day. Which seems like the more powerful connection?
So, put your smartphone down and make some time to truly develop a connection with someone. When it comes to your network, it should be quality over quantity.
Tatum Hartwig is a 4th year Communication Studies major with minors in Business Administration and Media & Screen Studies. Tatum brings experience and knowledge in the world of marketing and public relations from her two co-ops at Wayfair and New Balance. Her passion revolves around growing businesses via social media, brand development, and innovation. You can connect with Tatum on Twitter @tatumrosy and LinkedIn.


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The U.S. economy is in serious trouble. Unemployment is up, the housing market is down, and the net worth of average Americans had fallen by 6.7% over the past three years. Moreover, there's no reason to believe the immediate future will be any better than the recent past. That is, unless you're affiliated with Planned Parenthood, the abortion giant that has benefited immensely from the fact that taxpayer dollars have continually poured into its coffers no matter what the condition of the economy might be.
As a matter of fact, while the worth of the average American household continued its decline over the last year, the net assets of Planned Parenthood topped $1,000,000,000.00.
Just think of how proud Planned Parenthood's Board of Directors Chair Valerie McCarthy must be. While other Americans are struggling to live in such hard times, her organization is taking every penny it can get for killing preborn babies to the tune of 329,445 a year – more than the entire population of St. Louis—(for the 2009-2010 fiscal year). In exchange for stopping these hundreds of thousands of heartbeats, Planned Parenthood received 46% of their annual budget via funds taken from the American people through taxation and dispersed among current politicians' favorite special interests.
Again, think about it: Planned Parenthood's largesse from U.S. taxpayers for 2009-2010 was $487,400,000.00, and for the first time, Planned Parenthood topped $1 billion in net assets. Is this not blood money?
Ironically, however, in her forward to Planned Parenthood's annual financial report, McCarthy doesn't mention abortion even once. Rather, she touts figures that demonstrate Planned Parenthood's zeal to get condoms and birth control pills into the hands of millions of teenagers and to screen for the sexually-transmitted diseases that inevitably result from the licentiousness engendered by the organization's sex-ed programs. These are programs that pretend young people are only (to borrow from Madonna with apologies to the reader) "material girls (and boys) living in a material world," rather than spiritual beings.
Rush Limbaugh defends Rubio's debate answer: He's absolutely right that Obama knows what he's doing | Allahpundit
Time for Team Hillary to break out the gender card for young liberal women who prefer Sanders | Allahpundit


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The sound sculpture is very calming. Bonus: it matches my shirt.
There are two Starbucks in Terminal D. And knowing that is half the battle.
TSA Pre Check available at D22 & D30 checkpoint
TSA PreCheck is at the D30 checkpoint
Great restaurant options
the international terminal. so pretty!
For international flights
Terminal D is an awesome facility! Definitely stop here to grt something to eat or to do some quick shopping.
This is what an airport should be! 2 Express (Massage) Spas, variety of food (ethnicity, price, speed), chargers-even Ben & Jerry's! Cool beans! :-) 2 hrs to stretch & recharge before off 2 Hong Kong!
Skylink is the way to go, unless you have plenty of time for a nice walk to the other terminals.
Newer terminal, lots of food and shopping options!
Enjoy the art.
Pro tip: terminal D security is really slow now. Walk all the way down to the furthest south security entrance. Never a king wait
D24 is the place to sleep for overnight layovers
Really sucks to have NO (hardly one can find one) electric outlets to charge ones phone/laptop...
Best shops and restaurants in the airport
Beautifully redone terminal!
Best terminal at DFW ever.
If you have time visit Express Spa, Cool River, or III Forks. :-)
If your gadgets are running empty of batteries Look for this charging stations
Only bottled water seems to be Aquafina (I am partial to FIJI) and the only 1L bottle that I found was in the Rocky Mountain Chocolate Factory store. What a racket.
Best terminal!
Security clearance entrance is at the huge wishbone!
Best eateries at DFW!
Nicest international terminal with great vendors
Have mimosas at La Bodega pre-flight!
Best vegetarian options in D are Blue Mesa and Cantina Laredo.
Cousins BBQ. Nuf said.
Security opens between 4:15 and 4:30am. Don't worry about getting here earlier
Quiet and peaceful; quicker check-in than the cattle herd working C or gates 20+...
Fast Service at Starbucks! Quite a few restaurants to choose from. (4 of 4 petals via Fondu) Read more
Terminal D, if you don't know, has got it going on.
Great Qantas lounge, friendly Texan staff, gate lounges spacious, good post-Security shops & food, arrivals hall really nice... Simply the perfect airport to enter & leave the US!
Every gate has chairs with power outlets all over the place.
Make sure to enjoy the sophisticated lounge music being piped in to the ticketing and check-in area.
Fuddrucker's is awesome!
Sunday's during the fall, you can find most games on the Samsung TVs. Makes waiting for your flight almost as nice as your own living room. (Starbucks is by gate 30, for snacks.)
There is a free charge and internet station near Gate 21
Not enough Starbucks! The line is usually a long one, so don't expect a quick stop.
Use the sky link
Good Irish Pub and a USO
Skip the burrito place (360) - gave me a tummy ache
The duty-free store is very expensive.
Best terminal by far!!! Great people, great food and lots to look at :)
When restaurants are closed you can grab a sandwich to-go from TravelMart
Power plugs by seats in gate area. Top off the battery!
Tigin Irish Pub will fill you with Guiness and traditional PUB FOOD. DO IT.
Best terminal at this airport by far!
Great food! Reata tenderloin tamales amazing!!! L'Occitane has great travel specials too!
Samsung rest area, very comfy!


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Tags: im, sure, day, life, comeon, dasani, , nina, friend, sucking, stroking, your, cock, ok, nuff, said, porn stars
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Im sure this was the best day of his life. I mean comeon!! Dasani, Nina and friend sucking and stroking on your cock? ok.. nuff said


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With 1.7 million freelancers, we'll match you with the perfect talent.
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I need an artist to draw a black and white,. with blood splatters, horror comic book. It shall be 67 pages in length, all pencils (No ink) and the script is already written. This individual shall be able to mesh the two styling's attached. SinCity/Manga Style at is needed. This individual should also be able to draw Saltwater Crocodiles and other various bugs.
If you are interested and serious, we will begin extensive talks in hopes of amicably completing this project in a timely manner. Thank you.
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For more than 20 years, I was the health reporter on News Center 6. I'm now a regular guest on the Morning Report. Before I became a health reporter, I was a radiation therapist/dosimetrist at Maine Medical Center. In 2002, I left the world of reporting to manage marketing and public relations for Mercy Hospital. In 2011, I decided to pursue a longtime dream of being a freelance writer and launched my award-winning blog Catching Health with Diane Atwood. Check out the blog and health events calendar at catchinghealth.com. Catching Health is also carried by Bangor Daily News. In addition, I write a Catching Health column for the magazines Maine Women and My Generation.
After working in the field of family planning for nearly 12 years, I am now expanding my nonprofit, health care communications world to include cancer support services.


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ball in a box
by SaltyDoodler, published
Thing Info
A classic impossible object, the ball in a box. My amazing mother used to carve these from a solid block of wood back in the day. My first ever 3d object i used 3d tin hope it prints!
-My Mom carved these in the 70's and she got it from a book about Native American crafts i wonder if they had CC?
I printed it on a Rep 2 at medium settings with a raft and support, 15% infill 2MM layer height and 3 shells. I seem to get layer adhesion problems randomly a couple of inches off the plate I think i might try Whpthomas's "rock-solid build plate pad up upgrade" as well as his extruder upgrade the black PLA is "SainSmart" brand from Amazon and so far about half way through the roll have had 3 or 4 dreaded "air prints", due to slight diameter irregularities (a couple mm. max) in the PLA that stop it from feeding, but when it does print it looks real nice...
I have has good luck printing these on a rep 2 using Makerware to slice, No supports or raft. 3 shells, .15 layers and 50% infill. I love Whpthomas's ear raft supports http://www.thingiverse.com/thing:38272 I add one under each span that touches the build plate and one under the ball. I gave one to my mom she liked it, yours would too...
Thing Info
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Nice - I've made one original size and one 2x size (about 40mm) which I prefer.
well lets not be up on a thrown for a ball in a box like saltydoodler said his mom was making them in the 70's. just saying you dont own a tm on a ball in a box.
Cool, well my mother carved these out of wood in the 70's so she has us both! (and she learned it from a book about Native American crafts) I wonder if the indians had CC?
Cool, well my mother carved these out of wood in the 70's so she has us both! (and she learned it from a book) I wonder if the indians had CC?
Holy Toledo this sucker is HUGE. X and Y = 210000 mm and Z = 214384.9 mm
I tried to load the STL up in my favorite 3d program and it said it was an invalid format so I had to meshlab it (load it then save it) and those are dimensions this sucker is sitting at.
How about this one?


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Lisa G Artistry Makeup Artist
Mandy PowersModel Female Rancho Santa Margarita, California, US My MM URL: http://www.modelmayhem.com/MandyPowers
Mayhem # 1881475
About MeI am a professional and very experienced model and actress. I love what I do and I enjoy working with amazing teams to create beautiful images. Its just fun!
For bookings please contact me firstname.lastname@example.com
Serious inquiries only
I am fun to work with and love every aspect of the industry. I am looking to do PAID work but I will gladly take a look at TFCD work if I can ad it to my portfolio with your AMAZING work!! I am professional and would like to work with professional people who also like to have fun!! I look forward to hearing from you!! XOXO
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Credit NotesMercedes Benz Campaign 2015
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Eddie G Photography # 364152
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Are you T Measham?Claim your profile
Publications (1)2.46 Total impact
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ABSTRACT: Lithium administration was used in a patient with a clozapine-induced neutropenia and in another with complete agranulocytosis to assess whether lithium could stimulate neutrophil production. In both cases, following lithium administration, the neutrophil count was increased to the normal range within 6 days. In the patient who had presented a neutropenia, clozapine treatment was then reinstated in the presence of lithium and continued without the neutrophil count dropping into the yellow-alert range thereafter.


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Pittsburgh actually showing progress
At 18-18, Pirates have a .500 record this late in a season for the first time since 2004
Originally Published: May 11, 2011By Jayson Stark | ESPN.com
Let history reflect that on a perfect Monday evening in the second week of May, the Pittsburgh Pirates did something that hadn't been witnessed in seven stinking years.
They reached the summit of Mount .500 -- and kept on climbing.
Spray the ticker tape.
And check the standings.
Because when they'd finished high-fiving, the Pirates' record looked like this:
It wasn't exactly "late" in the season by normal standards. But we're not talking normal ...
Read full story
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I think I'd follow the advice you've been given here,...check up personally through phone or better yet, in person with the past and present horses he'd trained or has in training.
Ask if you can ride something he has trained to see if you like the way it feels. I always offer that.
No one can promise anything with a horse in a set amount of time. Every horse is an individual and deserves to be treated as such.


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Definition of within a whisker of in English:
informal Extremely close or near to doing, achieving, or suffering something: Jarvis came within a whisker of winning the game
More example sentences
- As the center's initial three-year grant drew to a close, CTFA came within a whisker of pulling its support.
- As a result of those finds, Cairn's shares have risen in steady steps from £4 to within a whisker of £15 today.
- He said the SRA wanted to scrap the route to shave a couple of minutes off the Manchester to London journey time, bringing it within a whisker of two hours.
Definition of within a whisker of in:
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text: Christmas isn't all Peace on Earth this Holiday Season in 8 Outstanding Suspense Stories of Murderers, Stalkers, Terrorists, Thieves, and Kidnappers. Criminal Christmas puts the Danger in the season of Mistletoe, Christmas Trees & Goodwill. Snuggle up by the fire with our books and enjoy Christmas like never before. This fabulous set is comprised of 6 Novellas (including never before published!), 1 Short Story and 1 Full Novel!


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Luigi Trezza 1931 - 2012 SPRINGFIELD - Luigi Trezza, 80, a long time resident of this city, passed away peacefully, Wednesday, May 30th at Baystate Medical Center surrounded by his loving family. Born in Salerno, Italy, Luigi had been a resident here for over 47 years. Luigi was a former employee of Hampden Brass & Aluminum Cast Production Co., retiring after 38 years of employment. He was an avid gardener and enjoyed wine making. Luigi cherished his family and his home in Springfield, and will be remembered as a friend to everyone. He is survived by his loving wife of 54 years, Carmela (Liquori) Trezza, a son Joseph Trezza and his wife Deborah of Wilbraham, MA, two daughters, Carmela Fitzpatrick and her husband Richard, and Anna Pepin and her husband Alan, all of Ludlow, MA, eight grandchildren, Joseph & Julia Trezza, Christopher, Brianna, & Ariana Fitzpatrick, Michael & Samuel Pepin, and Richard McCormick III, his siblings, Vincenzo, Guiseppe, Giovanni, Maria, Rose, Nunciata, Antoinetta, & Rita, all of Italy, his faithful friend and brother-in-law Antonio Barbarisi of Springfield, MA, and his many nieces, nephews, & friends. Funeral services will be held Monday, June, 4th, 2012 at 8:45 am from the Forastiere-Smith Funeral Home, 220 North Main St., East Longmeadow, Ma, followed by a Liturgy of Christian Burial at 10:00 am in Our Lady of Mt. Carmel Church, 123 William St., Springfield, MA. Burial will follow in St. Michael's Cemetery. Family and friends may gather at the funeral home on Sunday, June 3rd from 4:00 - 8:00 pm.
Funeral Home
Forastiere-Smith Funeral Home
220 North Main Street
East Longmeadow
(413) 525-2800
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Published in The Republican from June 1 to June 3, 2012
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Ariana Grande Releases "Focus" Music Video
Oct 30, 2015 10:19 AM EDT
Ariana Grande released the music video for her new single "Focus" late Thursday night. And though Grande is one of the biggest and most talented pop stars out there right now, her first single of her forthcoming album is ... not great. The music vide… Read more


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Favor Hamilton's name dropped from Big Ten award
Updated: July 2, 2013, 11:39 AM ETAssociated Press
PARK RIDGE, Ill. -- The Big Ten female athlete of the year award no longer is named for the Olympic track star from Wisconsin who later acknowledged working as a prostitute.
Big Ten spokesman Scott Chipman said Tuesday that Suzy Favor Hamilton's name was removed from the award after discussions between the league and Wisconsin.
Minnesota hockey player Amanda Kessel was named the winner last week. Kessel was also the national player of the year after leading the Gophers to an undefeated ...
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Respond to Review of Mod's Cafe at the Thirsty Scholar
by Scottish Clare
Review: We visited the Thirsty Scholar on the evening of 13 Feb 2012 for a drink. For a pub whose website highlights the availability of vegetarian/vegan food and drinks it was very disappointing. We asked the girl behind the bar which beers were vegan and she had to go and ask the manager. She came back with a list of lagers that were on tap so we had to ask her to go and find out about the real ales. She went to speak to the manager again - he did come out and tell us that usually they had veggie/vegan real ales but they didn't have their usual brand on at that time. He did go to check the brands they did have and eventually confirmed that one of their real ales was veggie. We had also asked about vegan wine but never got an answer and by the time we'd sorted out the beers we couldn't face asking again. It was a shame as we actually thought it was quite a nice pub but the lack of knowledge shown by the staff was very poor. I don't know if they still do food or not - the website says they serve until 6:30pm but we didn't see any menus out even though we arrived before then.
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Vintage snowmobilers were showing their Christmas spirit on Saturday.
The White Pine Lodge held their fourth annual Vintage Snowmobile Show in Christmas. The show featured old snowmobiles that you may have seen and plenty of others that you probably haven't. Organizers of the event aim to attract attention to these antique sleds.
"These guys travel all over Michigan, Ontario, Wisconsin, Minnesota to display their sleds and we do one late in the season and it's about the last one of the year so they enjoy coming out for the last time," said Ivan Hansen, owner of the White Pine Lodge.
In addition to the show there were raffles and silent auctions that people could participate in.
All of the proceeds from the event go to the Top of the Lake Snowmobile Museum in Naubinway, which showcases vintage snowmobiles.


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determine the speed of Earth's orbital motion in meters per second
Taking Earth's orbit to be a circle of radius , determine the speed of Earth's orbital motion in meters per second.
Solution This solution is FREE courtesy of BrainMass!
Need to work out how far the earth has travelled or in other words the displacement of the earth given as (delta r). This change can be worked out because we are told that the earth has a circular orbit of a known radius.
Simply using the equation for a circles circumference will give us the distance the earth travels in 1 year.
See attachment below for a detailed response.


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RANCHO CORDOVA, Calif., April 1, 2013 (GLOBE NEWSWIRE) -- ThermoGenesis Corp. (Nasdaq:KOOL), a leading supplier of enabling technologies for the processing, storage and administration of cell therapies, today said equipment is on order for its AXP ® AutoXpress ® System (AXP) from Crioestaminal, a leading cord blood stem cell bank located in Cantanhede, Portugal.
- The BioArchive ® System, an automated cryogenic device, used by cord blood stem cell banks in more than 30 countries for cryopreserving and archiving cord blood stem cell units for transplant.
- AXP ® AutoXpress ® Platform (AXP), a proprietary family of automated devices that includes the AXP and the MXP ® MarrowXpress ® and companion sterile blood processing disposables for harvesting stem cells in closed systems. The AXP device is used for the processing of cord blood. The MXP is used for the preparation of cell concentrates, including stem cells from bone marrow aspirates in the laboratory setting.
- The Res-Q ® 60 BMC/PRP (Res-Q), a point-of-care system designed for the preparation of cell concentrates, including stem cells, from bone marrow aspirates and whole blood for platelet rich plasma (PRP).
CONTACT: ThermoGenesis Corp. Web site: http://www.thermogenesis.com Investor Relations +1-916-858-5107, or email@example.com


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UPDATED: Two India companies have withdrawn sponsorship of a Wharton School business conference after conference organizers un-invited an Indian politician who has been banned from the United States since his government failed to block massacres of Muslims in 2002.
The student-run Wharton conference courted, then snubbed, Gujarat State chief minister Narendra Modi. He is the popular, Hindu-nationalist, private-business-oriented BJP (Indian People's Party)'s likely candidate to be the next Prime Minister of India, says the Times of India here.
The event's lead ("platinum") sponsor, Adani Group, a port, power, coal and gas conglomerate, and its billionaire chairman Gautam Adani "withdrew the sponsorship, and opted out of the event, citing commitments here," reports the Indian Express here.
Another India company, software outsourcing giant Hexaware Technologies, which counts Blue Bell-based Unisys and Germany- and Newtown Square-based SAP AG among its partners, "withdrew sponsorship for the Wharton India Economic Forum (WIEF) on Wednesday and company chairman Atul Nishar opted out of the event," the Express said.


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CHIP QUIK SMD291AX10 Solder Paste, SynTECH, 183 °C, 35 g
Image is for illustrative purposes only. Please refer to product description.
- Manufacturer: CHIP QUIK
- Newark Part No.: 84R8665
- Manufacturer Part No SMD291AX10
Product Overview
- Supplied in 10cc syringe
Product Specifications, Documents & More
- Melting Temperature: 183°C
- SVHC: No SVHC (15-Jun-2015)
- Solder Alloy: 63, 37 Sn, Pb
- Weight: 35g
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Over the last couple of weeks myself and Andrew have been out talking to IT Pro's about Windows Server and Microsoft Virtualization platform. It's clear to us that many of you have not had much experience with Hyper-V or are struggling to keep up with the pace of change that is going on in the virtualization space. We definitely hear you!
With that in mind we have two new programs that you may have not heard of that were recently announced over on the In the Cloud blog.
The first new program is a new Microsoft Virtualization Certification that has been designed around Windows Server 2012 R2 Hyper-V and System Center 2012 R2 Virtual Machine Manager. This certification is geared towards folks that already have skills in VMware technologies or may have a VCP.
The second program, which compliments the first is a brand new website called Virtualization2. This site has a ton of resources designed to help you learn more about Hyper-V and get certified on the new R2 wave!
I encourage you to check out these new resources because as we all know it's increasingly becoming a multi-hypervisor world out their and if you're going to accelerate your career you will need to have skills in both platforms. So to wrap up:
And for those that haven't been to one of our current IT Camps we will see you there soon as we still have 4 cities to go on this current round!


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very cool- good character, she brings a lot to the series-
Very nice legs! I'd like to be able to feature this as part of my "Nylon Beauties" group. Thank you!
Great figure and legs!
Great pose!
Very preetty!!!
What incredible costume and equally amazing legs! Would you accommodate a fan asking you for a picture pose of you kicking him in the groin while in costume?
great pose!
Wow, great job on the costume and I love the pose
you look great as Black Canary, love the stern, powerful looking pose. Very well done indeed
She isn't from Young Justice. She has been in Green Arrow comics before and has her series if i'm right.
she appears in it big difference....she's green arrow's main girl.
The version I am cosplaying is from Young Justice, which is a specific design, so I don't understand what your point is. Obviously, she's been in other DC Comics franchises.
oh my bad. Sorry for the mix up. I forgot to say you look amazing. I don't like starting fights when I'm in the wrong. So please forgive me. Btw, have you seen her new 52 look?
It's all good! And thanks. I have seen the new look; still not sure how I feel about it though.
The whole full bodysuit thing is a change for her that I like. But hey I bet there are girls out there going nuts over it. I gotta ask you a serious question...some of the female characters female cosplayers cosplay as are very interesting. I'm talking about the one that wear little to nothing. I gotta ask what type of appeal characters like that have for you? Most girls I know see those characters as whores/sluts.
Very Cool!
I like her a lot
A pretty nice cosplay, but the girl is very cute
I think this is my favorite of your depictions. In the first place I like the design; in the second place it's very flattering.
Excellent cosplay. Great capture.
It's so beautiful of a portrayal I could literally scream....
I am a big black Canary fan, well posed and played
but I am so glad she went to heels and fence-net's
but I am so glad she went to heels and fence-net's


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To make reservations by phone, call 1-800-257-3000 in the USA and Canada (or any of our worldwide reservation telephone numbers).
It Pays to Book Direct™
It Pays to Book Direct™
TownePlace Suites Seattle South/Renton
300 SW 19th Street
Renton, Washington 98057 USA
300 SW 19th Street
Renton, Washington 98057
Seattle-Tacoma International Airport - SEA
Airport Phone: +1 206 433 5388
Hotel direction: 5 miles E
Complimentary 24 hour hotel shuttle // By car from airport take Interstate 405 North to exit 1 for Tukwila/West Valley Highway. Turn left at the traffic light onto Interurban Avenue and proceed to SW Grady Way. Turn right and continue to Lind Avenue SW. Turn right and travel to SW 19th Street. Turn left and the hotel will be on the left.
King County International Airport/Boeing Field - BFI
Airport Phone: +1 206 296 7380
Hotel direction: 8 miles NE
This hotel does not provide shuttle service.
Travel northeast toward Airport Way South. Turn right and follow Airport Way South to the South Boeing Access Road. Turn right and from the access road take the WA-900 East ramp. Turn right onto Martin Luther King Jr Way South/WA-900 East. Turn right onto 68th Ave South. 68th Ave South will become Monster Road SW. Stay straight and proceed onto Oakesdale Avenue SW. Turn left onto SW 16th Street. Turn right onto Lind Avenue SW. Turn left onto SW 19th Street and hotel will be on the left.
For more information call the general manager of the hotel


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6 Reviews
I was scared to try it, but once I did, I loved it! Such a unique taste!
I think I made the mistake though of using unground sea salt. I used big ol salt crystals in mine, and it was too salty and I had to spit it out.
So, use ground sea salt. :) You'll love it.
Awesome! This was outstandingly delicious :) It's very satisfying and you really only need a small portion of ice cream to feel satisfied [how great is that?!] As others have mentioned, I can't really explain how this tastes, but it is wonderful. If you are an olive fan you'll enjoy this a lot! I've already eaten this 2 nights in a row! Thanks for posting!
Annnnnd this is delicious. It is similar to the savory bread and olive oil taste but colder. Slightly bitter on the front, fruity, and nutty. Then smooth and salty where it counts. Sweet finish on the back end. I truly enjoy crusty bread and olive oil. This is glorious. It's kind of like when you have corn or something like that with olive oil. It just takes the sweet/savory combination and adds a surprising temperature adjustment. Yum. I might add rosemary to be cheeky.
Olive oil and ice cream? This sounded so interesting, I had to try it right away! I was apprehensive about what the taste was going to be like...I can't explain it either, but like the previous reviewers say, it's pretty good!
Well, I certainly never would have thought this one up on my own! :) This combo was surprisingly good, and I love that it is so different...not the usual, expected "same old same old". Thanks for posting!
delicuios. i never would have thoughtto try this. used all organic ingredients; a very good quality ice cream, which i am sure is a must. served with a small sqare of organic dark chocolate. this is great; will make this treat again.


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A complete travel resource guide featuring restaurants, hotels, activities, museums, events, shopping, nearby destinations, and iconic Cajun Country recipes.
- Main
- Restaurants & Bars
- Things to Do
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- #64N64-Sponsored-
Where To Stay in New Orleans
Up Next
Where To Stay in New Orleans
These NOLA hotels are hard to beat. All in or near the French Quarter, they're tops for location, style, and Big Easy flavor.Start Slideshow


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The map below shows all of our facility and greenspace locations around Berwyn. Mouseover each to see details and/or link to more information.
Edward A. Karasek Park
The Berwyn Park District entered into a 99 year lease agreement with the City of Berwyn to help develop, maintain, and manage the park site which offers a tranquil, passive environment for patrons and residents alike to rest, relax and enjoy a treat or meal while taking in this newly landscaped parcel of green space. As part of the partnership this parcel of land , which had contained underground leaking fuel tanks was remediate to remove the tanks and all contaminated soil. Clean soil and sod were then installed to provide for settling before the current development was undertaken.
Karasek Park exemplifies the commitment of the Berwyn Park District and City of Berwyn, through partnership, to consistently exceed the expectations of residents. As Karasek Park continues to grow, Where Park Meets City is embodied through its integration into the Historic Depot District.


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Are you Hemvala Chirdchupunseree?Claim your profile
Publications (3)5.34 Total impact
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ABSTRACT: The purposes of this study were to investigate the inhibitory effects of two lignans, phyllanthin and hypophyllanthin, on the function of P-glycoprotein (P-gp) and multidrug resistance protein 2 (MRP2), using the in-vitro model of Caco-2 cells. In addition, the effect of prolonged exposure to these two compounds on the expression of active P-gp was also determined. The activity of P-gp and MRP2 was determined in the uptake assays by monitoring the intracellular accumulation of their specific substrates (calcein acetoxymethyl ester and 5(6)-carboxy-2',7'-dichlorofluorescein diacetate, respectively) with fluorescence spectroscopy. Hypophyllanthin and phyllanthin inhibited P-gp function with comparable potencies, but neither compound affected MRP2 activity. When the lignans were washed out before addition of substrate, the inhibitory action of both compounds against P-gp function was lost. These results suggested the reversibility of the inhibition. Moreover, prolonged exposure of the Caco-2 cells to both lignans (up to 7 days) had no effect on P-gp function. Phyllanthin and hypophyllanthin directly inhibited P-gp activity and did not interfere with MRP2 activity. It was likely that both phyllanthin and hypophyllanthin could reversibly inhibit P-gp function.
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ABSTRACT: The purpose of this study was to investigate the modulating effects of phyllanthin and hypophyllanthin on vascular tension, using in the in vitro model of isolated rat aorta. Our results indicated that both phyllanthin and hypophyllanthin significantly relaxed the sustained contraction induced by phenylephrine (PE) in a concentration-dependent manner. In addition, endothelial removal had no significant influence on the vasorelaxation responses of the aortic rings toward these two compounds. Furthermore, both compounds inhibited the contraction of aortic muscle provoked by either PE (1 μM) or KCl (40 mM) as well as the spontaneous contraction of the Ca²⁺-depleted muscle. In high K⁺-Ca²⁺ free solution, phyllanthin (100 μM), but not hypophyllanthin, significantly inhibited the contractile responses upon cumulative addition of CaCl₂. Both compounds (100 μM) significantly inhibited PE-induced contraction in Ca²⁺-free condition, but could not affect caffeine-induced contraction. Taken together, phyllanthin and hypophyllanthin could modulate the vascular tension via the endothelium-independent mechanisms. The modulating effects of both compounds were possibly involved with the blockade of Ca²⁺ entry into vascular smooth muscle cells and inhibition of PE-mediated Ca²⁺ release from sarcoplasmic reticulum.
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ABSTRACT: To investigate the protective effect of phyllanthin (a known principal constituent of Phyllanthus amarus Schum. et Thonn.) on ethanol-induced rat liver cell injury. Primary culture of rat hepatocytes (24h culturing) were pretreated with phyllanthin (1, 2, 3 and 4 microg/ml) for 24h. After 24h pretreatment, cells were treated with ethanol (80 microl/ml) for 2h. Ethanol decreased %MTT, increased the release of transaminases (ALT and AST) with the increase in the production of intracellular ROS and lipid peroxidation. Phyllanthin demonstrated its role in protection by antagonizing the above effect induced by ethanol. Phyllanthin also restored the antioxidant capability of rat hepatocytes including level of total glutathione, and activities of superoxide dismutase (SOD) and glutathione reductase (GR) which were reduced by ethanol. These results suggested the hepatoprotective effect of phyllanthin against ethanol-induced oxidative stress causing rat liver cell damage through its antioxidant activity.
Top Journals
Chulalongkorn University
Krung Thep, Bangkok, Thailand
- Department of Pharmacology and Physiology


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Kal Penn: Enough with the Cynicism and Disappointment, Time to Re-engage!
[caption id="attachment_34241" align="alignright" width="300" caption="Kal Penn speaks at a Democratic rally at University of Southern California, October 2010.
The first female president of the Disciples of Christ.
You would think attempting to summarize my feelings on having been asked to deliver the Benediction at the Inauguration of President-elect Barack Obama-would be simple. In fact, it's quite a challenge; given the flood of emotions I have experienced ...


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Just promise me you won't ring in the new decade by clutching onto a toilet
You must be Logged in to post a comment
Haha ohh 954. Were such a classy breed.
How else are you supposed to do it
been there done that.
12:14 ps I think your a huge retard.
The new decade starts in 2011 not 2010.
i excpected somthing funnier from lauddyy.
hey b, FIRST. xoxo-s
I am so honored to live in the 954 !
12:14 so 1990 was part of the 80's.
Not funny. TFLN is getting deleted from my apps.
hahahah and you do? :)
"Okay Mom!!"


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This week on Geek Speaks..Fiction!, horror author Samuel Sattin joins us to share what made him geek out while writing his new book, The Silent End, a chilling novel for mature teens and adults alike. His work has been described as being full of fun, terror, tragedy, and delight.
Welcome, Sam!
About the author: Samuel Sattin is a novelist and essayist. He is the author of League of Somebodies, described by Pop Matters as "One of the most important novels of 2013." His work has appeared in The Atlantic, Salon, io9, Kotaku, San Francisco Magazine, Publishing Perspectives, LitReactor, The Weeklings, The Good Men Project, and elsewhere. He has an MFA in Creative Writing from Mills College and an MFA in Comics from CCA. He's the recipient of NYS and SLS Fellowships and lives in Oakland, California.
It's not overly difficult to describe what I geeked out on while writing The Silent End, mostly because the main character is a grade-A certified nerd, seventeen and on the edge of emotional collapse in many ways.
Continue reading Horror Author Sam Sattin Creates an Imaginary Game For His Book


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Best Supporting Player (1999)
Kim Ostrenko
Sam Shepard's characters are many things: schemers, losers, maligned heroes. But they're rarely female. When women are present, as in the case of Cecilia, a would-be love interest of the protagonist in Shepard's 1994 play Simpatico (produced this past summer by the Florida Shakespeare Theatre, now called GableStage), they're odd ducks, intruders in a strange male universe. Sometimes they get lost amid all the testosterone. That wasn't the case with cast member Kim Ostrenko. The actress may have been playing one of the oddest creatures in the Shepard menagerie, but she deftly embodied all of Cecilia's contradictions, moving from utter blankness to incisive maneuvering in the blink of an eye. She may not have been a star in this play, but Ostrenko's performance was indubitably a star turn.
More People & Places Awards
Best LobbyEden Roc Resort and Spa
Best CleavageEl Nuevo Herald
Best Weekend GetawayEverglades City/Chokoloskee
Second Best New LawLocal campaign finance reform


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Sertomans! Please be reminded of the District Meeting being held this Saturday . . . we need a representative from each Club! Schedule is as follows:
10:00 – 11:00 – NC Endowment Fund Meeting
11:00 -12:00 – District Meeting and PAC Meeting
12:00 -1:00 – Lunch provided by District Governors
1:00 -3:00 – Camp Committee Meeting
Tarheel Sertoma Lodge, Hwy 54 in Carrboro (Chapel Hill address).
Please make every effort to attend!! We need you there!! We need a head count too for lunch so please let us (email Renee Ward or Randy Mercer) know as soon as possible how many from your club will be attending.
Renee Ward


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Jenny MaharryTwitter Stats
@JMaharry - Tracking since August 19, 2013
Jenny Maharry Tweets
@JMaharry has posted 1 tweets in the last 30 days, which translates to an average of 0.0 tweets per day.
Jenny Maharry Followers
@JMaharry has 56 followers.
This account is #70,332,552 in the worldwide rank of the most popular Twitter users.
Jenny Maharry Following
@JMaharry is following 62 Twitter accounts.
Last month this account followed 12 users.
Jenny Maharry Predictions & Milestones
@JMaharry will hit 59 followers in the next 3 months, and 68 in one year.
You are on Jenny Maharry's Twitter stats page
We track these Twitter stats since August 19, 2013 . You can see how many followers Jenny Maharry lost or gained and what the prediction is for tomorrow or the next 15 days, together with all kinds of other stats like rank compared to all Twitter users, tweets etc.
Why don't you give it a try and compare Jenny Maharry to yourself ? Or if you are Jenny Maharry get even more feature rich & up-to-date stats with Premium & Pro Twitter Stats.
Twitter Counter is the #1 Twitter stats site powered by Twitter. It all started in June 12, 2008 and we grew rather rapidly because of our Twitter Counter badge. The button is a nice small image that shows your visitors how many followers you have on Twitter. Within a year the button was on many many blogs around the world and we displayed more than 100 million buttons in one month. We track follower stats for over 180 million users now.


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The Next Big ThingJournal Entry: Wed Jan 16, 2013, 10:43 PM
Last week I was tagged by KWhipkey at her blog, Nightwolf's Corner in The Next Big Thing. This one looks like fun, even though I'm not usually one to participate in memes. And, hey, since A Foundation in Wisdom is coming out soon, this is a great
This is presented as an interview of sorts. Since I'm rather new to the world of blogging, I cross-posted to deviantART. (For the record, my blog can be found here: www.anorthogonaluniverse.com). At the end I'll point you to five people whose work I think you should check out
Onward and forward!
What is the working title of your book?
The book has gone through as many titles as it has identities, which is not unusual for me. I'm very good at planning. While I may fall a bit short is in the sticking-to-the-plan department, I'm a superstar at doing what I feel like doing.
Hold on to your hats! This is a surprisingly difficult question to answer, especially without giving out the history of the story.
The book was originally called History of the Wiener Dog. It was a story about a mathematician and a historian trying to outdo each other telling outlandish tales about common things. It was intended to be a collection of short stories, loosely tied together by the premise of a mathematician hitchhiking a ride from a historian. One of the tales, A Brief History of the Wiener Dog, I wrote for my then-girlfriend (who is now my wife) over ten years ago! Am I really that old??? Make a note, wiener dogs are the foundation of a long, happy relationship. I'll love you as long as a dachshund.
Some time later I sat down to write new stories, since up until 2007 I was just collecting old ones. The first one was about a Renaissance girl named Mara, who wanted to join a circle of scholars. It happened to be written at a time when a certain mathematician, who should be sleeping right now, was studying for his first qualifier exam so he could join a research group. It turned out to be a handy outlet, and the story grew to novel-length very quickly. I realized I now had a novel series, and since it was no longer about long dogs, I changed the title to A Constellation in the Water.
The basic premise changed drastically over time. Now, only Sheridan, the mathematician, told stories. I realized I could connect them in a much more profound way. John Bartlebee and Sheridan were becoming much more integral to the plot itself. I realized I needed to set the stage for a few new plot twists, so I introduced A Foundation in Wisdom as a prequel to Mara's story. About this time, I decided I didn't like the series title, and swapped it with that of the very last chapter. The title, A Constellation in the Water, sounded poetic, but had absolutely nothing to do with the series.
An Orthogonal Universe was a much better title. It's a reference to a line in an early chapter about story-telling. It sat around for a while. For a long time it was an "illuminated hypertext novel", being published as a serial work online. It turned out that really wasn't a good idea, at the current time, for various reasons. I decided to re-work the story into a more traditional novel format. I then split the series into four books, one for each of Sheridan's tales. The first "stage" (a reference to stage of history) is A Foundation in Wisdom.
As for its original incarnation, I'll likely revisit the idea in the future.
What genre does your book fall under?
"Fantasy" sounds like the best fit. I suppose I could call it "Mathematical Fiction," a play off of "Science Fiction," but I'm not sure that's such a good idea.
What is the one sentence synopsis of your book?
It turns out condensing a 45,000+ word novel into a single sentence is harder than condensing it into a two-paragraph blurb. It also turns out I hadn't thought to work out a one-sentence synopsis. So, here goes a shot:
After a hitchhiker suggests the world is ending, John demands proof, and is given it in the form of a story about a mathematician who tried to prove the world didn't exist.
Where did you get the idea for your book?
If anything, A Foundation in Wisdom is a satire of the world of academic research through the eyes of a young Ph.D. student. The all-too-familiar elements of university life are there: the vast hurdles a student must climb in order to get "obvious" advice, seemingly indeciphrable texts from the land of nonsense, that one proof that's impossible to write, and the epitome of frustration: the seemingly infinitely long process of writing that thesis. They do say write from experience...
I wrote the first draft in 2008, during the short period between the completion of my qualifying exams and when I found a research group. This was a hard stage in the Ph.D. process, because it involved tracking down hard-to-find faculty members and figuring out how to ask them a million questions about their research without sounding like an idiot. Read the chapter about the wise-man, and you'll get a pretty good sense of what this stage is like.
Thankfully, once I did find an advisor, things went rather smoothly. My own research group worked well together, and my thesis advisor knew how to keep us pointed toward our goals. Of course, one of those goals was graduating, which pretty much put the book on hold. When I completed my degree in 2010, I came back to the manuscript.
Who or what inspired you to write this book?
I draw inspiration from my surroundings and experiences. The second book got the ball rolling, so I suppose I'd say the second book inspired me to write this one.
How long did it take you to write the first draft of your manuscript?
The 2008 version took forever to write. The 2010 version was written, almost entirely, in the one week period I was visiting my in-laws in Spokane, WA. I consider them both "first drafts", since the stories had significantly different plots.
What other books would you compare this story with in your genre?
The two comparisons I'm given most frequently (and I'd agree with them) are Alice in Wonderland and Hitchhiker's Guide to the Galaxy.
Charles Dodgson was a mathematician, and many references to mathematical concepts can be found in his works.
I wrote A Foundation in Wisdom while I was studying for the qualifying exam in Linear and Lie Algebra at NCSU. Sometimes on purpose, and sometimes by accident, much of what I studied surfaced as references in the story: There is a character named after Sophus Lie, the "Father of Lie Algebra"; An embodiment (and anagram) of the Nullspace called "SanCullep Island"; and, well, the list goes on.
At one point I thought it would help me understand Linear Algebra if I thought of the various concepts as physical places. As it turns out, like Schrodinger's Cat, abstract and/or theoretical ideas don't necessarily translate well to practical ones.
Which actors would you choose to play your characters in a movie rendition?
I have never thought of my books this way, so I don't have a good answer. I wouldn't expect the author to get much of a say in anything beyond signing a contract. If I could give input, I'd probably just hand the casting director some of the artwork I've done over the ages.
Will your book be self-published or represented by an agency?
I am self-publishing this title. It took me a long time to reach this decision, but ultimately, I determined I'd much rather retain creative control over the project. There are a few reasons for this. First, it's a series, and I'd like to make sure the earlier books are set exactly how I want them. Someday I might revisit the "illuminated hypertext" format. There's also a more practical issue. I'm an educator first, and during the school year, my students and the college are my top priorities. I wouldn't want to lock myself into a contract that requires I do anything according to a schedule.
What else about your book might pique your reader's interest?
Here's the blurb!
History repeats itself. This is what I taught, and always believed. Then I met Sheridan, a man hitchhiking down the highway without a care in the world - a lonely figure who told me history, and the world, was ending. His evidence was the story of a mathematician who tried to prove the world didn't exist.
It was a silly proposition. Nobody can prove the world doesn't exist. But as I became more convinced Sheridan was right, that the proof lay at the edge of reality, I could only wonder, where would we go?
I think anyone who has ever written a research paper, thesis, or presented at an academic conference could identify with some of Marcus's difficulties.
Now, go check out these people's work!
1. D-E-M-Emrys has a novella in the works, It Began With Ashes. The prologue is online. fav.me/d5jka4y. Definitely recommended if you're a fan of fantasy.
2. b-nicoleT has a Post-Apocalyptic novel, The Mouse. I found the first parts intriguing, and it looks promising. fav.me/d5qfx3p.
3. I've been following SpiralofDragon and Violet for a while. It's hard to find illustrated novels on dA. The artwork has a very intriguing style.
4. On the subject of graphic and illustrated novels, go check out Griatch-art's work. If you get into the GIMP/MyPaint/open-source art community, you'll likely run into his work. It's a great demonstration of what FOSS graphics software is capable of. Where Red Apples Lie is definitely worth reading: fav.me/d373r85
5. I'm going to point everyone to an old favorite of mine. Go check out Evil Editor if you're planning to query an agent or publisher. He'll critique your query letter and/or synopsis.
This Journal Skin was designed by Night-Beast
The Next Big Thing by merrakWatch
©2013-2016 merrak
Very nice. Glad to see you put my tag to good use.
I need to work on my blogosphere presence. Blogging is something I'd like to do, but I have too many things competing for my time right now.
Hey thanks for the mention! I might steal/borrow this meme for use over on my journal, if that's ok with you?


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Women's NCAA Tournament Norman sub-regional
→Teams: No. 3 Oklahoma, No. 6 Georgia Tech, No. 11 Arkansas-Little Rock, No. 14 South Dakota State Schedule →Today: Open practices — Georgia Tech, noon-1 p.m.; Arkansas-Little Rock, 1:05-2:05 p.m.; Oklahoma, 2:10-3:10 p.m.; South Dakota State, 3:15-4:15 p.m. →Sunday: Georgia Tech vs. Arkansas-Little Rock, 6:16 p.m.; Oklahoma vs. South Dakota State, 8:30 p.m. →Monday: Closed practices →Tuesday: Georgia Tech/Arkansas-Little Rock winner vs. Oklahoma/South Dakota State winner, 8:30 p.m. →Tickets: All-session tickets $46 adult, $31 youth. Go to www.SoonerSports.com or call (800) 456-4668. →TV schedule: ESPN2 (Cox 28) with Dan McLaughlin and Fran Fraschilla


text:
Tampa Bay Rays
Sponsored By
Kinatrax: The Story Behind Baseball's Newest TechNew technology looks to change our understanding of the art of pitching.
This Week In Baseball: New Technology Could Help Better Understand PitchersBaseball has consistently been the leader in finding an innovative way to look at a sport that's been around for well over 100 years.
Pirates Utilityman Sean Rodriguez: Let Pitchers Hit In Both LeaguesOff to a hot start this season, Pirates utilityman Sean Rodriguez joined the Starkey and Mueller show to talk about his role on this team and what it's like playing under Clint Hurdle after spending time with Joe Maddon in Tampa Bay.
Liriano Pitches 3 Scoreless Innings, Pirates Beat Rays 4-3Francisco Liriano pitched three scoreless innings in his second spring training start, helping the Pittsburgh Pirates beat a Tampa Bay Ray' split squad 4-3 on Tuesday.
Pirates Trade For Infielder, Designate Sanchez For AssignmentThe Pirates have acquired infielder Sean Rodriguez from the Tampa Bay Rays.
Playoff Pinch Hits: James Shields-Wil Myers Trade A Success For RoyalsThe Kansas City Royals traded for starting pitcher James Shields before the 2013 season, giving up top hitting prospect Wil Myers.
Pirates GM Neal Huntington On Trade Deadline: "The Right Move Was No Move"After coming up empty at the Major League Baseball trade deadline, Pirates General Manager Neal Huntington held firm to the idea that no move was the right move for his club.
Pirates Also Miss Out On Rays Starter David PriceJust minutes before the trade deadline, word came out that the Tampa Bay Rays, Detroit Tigers and Seattle Mariners worked out a 3-team deal to send Price to the Tigers.
5 Crazy Events From Major League Baseball You May Have Missed
American League Mid-Season Team MVPsSometimes a team's best players don't make the All-Star team. Here are the American League's mid-season team MVPs.
Price Strikes Out 11 Pirates, Rays Win 5-1David Price struck out 11, becoming the first pitcher in 10 years to fan at least 10 in five straight starts, and the Tampa Bay Rays beat the Pittsburgh Pirates 5-1 on Wednesday.
Rays' Wil Myers Could Top His Rookie Of The Year SeasonWil Myers gives the Rays legitimate power in the middle of the batting order.


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Calidris melanotos
IUCN Conservation Status: Least Concern
Ian Davies
A medium-sized, chunky shorebird, the Pectoral Sandpiper is found most commonly on mudflats with short grass or weedy vegetation and seems more at home in the grass than in the water.
Breeds in wet coastal tundra. Migrates and winters in wet meadows, mudflats, flooded fields, and shores of ponds and pools.
Formerly abundant in 19th century, but were much reduced by market hunting. Little information on current population trends. This species is on the 2014 State of the Birds Watch List, which lists species most in danger of extinction without significant conservation action.
All About Birds blog, First-Ever World Shorebirds Day Highlights Need for Conservation, September 5, 2014.
Contact the Lab | Privacy Policy | Terms of Use | Site CreditsCopyright © 2015 Cornell University
The Cornell Lab will send you updates about birds, birding, and opportunities to help bird conservation. You can unsubscribe at any time. We will never sell or give your email address to others.


text:
ok, first off, let me run down who I am and what not.
I'm a father, a husband, a sailor, a liberal conservative, a lover of music, a lover of the outdoors, and an artist of words. I'm in good shape physically, maybe like 5 or 10 lbs to lose, but still I'm in good shape. 3 weeks ago I started riding my bike to work due to various motivating forces, and I love it.
I drive in with the bike in the bed of the El Camino on Monday morning and drive back on Friday afternoon when I get out of work. All the time inbetween, I ride to and from work. The shortest route I take is a hilly and challenging (at least for me) 9.4 miles. The longest route I take, now that I have my new city tires and wheels, is about 16.7 miles ( I have yet to take it, but I'm starting out this Monday!!!).
I know what it is to push myself and not hurt myself. I started using Endurox (from GNC) as my recovery drink, in tandem with my Megamen powder vitamins.
I want to ask, am I overtraining? Am I pushing myself too hard? And is my choice of recovery drink a good one?


text:
Best Chinese Restaurant (2010)
Shanghai Chinese Restaurant
The family that owns this Chinatown eatery knows what it's doing. The salted pork ribs are a must-try here. Also get the wonton soup, a flavorful broth holding fresh dumplings packed full of ground pork. The noodle soup with brisket is too good to pass up, so you might have to make a choice to eat one dish here and take one home. In fact, all the classic dishes are done right. The fried rice is superb, and the lo mein is straight out of an old-school Chinese diner. The egg rolls are fat, flavorful and extra crispy, with lots of meat. The owner's entire family will be there to serve you, and you might see them sitting down to eat the same food you just ordered.
More Awards from This Winner
Location Details
More Food & Drink Awards
Catalan and the Bayou CityA distinctly Houston cuisine is emerging
Puerto Rico and BeyondTour the world at four-table Montrose restaurant Tex-Chick
Best Pre- or Post-Theater RestaurantThe Grove
Best Tex-Mex RestaurantPico's Mex-Mex


text:
These sites are intended for patients and caregivers in the United States
All Products
Cardiac Rhythm Management
Structural Heart
All Resources
Instructions for Use
(Product Manuals)
Product Catalogs
CRM EMI Resources
MRI Resources
Product Performance
Patent Information
Innovative Ideas Portal
The wireless design of the QUANTIEN™ integrated FFR system allows you to configure your cath lab environment exactly the way you like – without the clutter of cables.
Wireless AO pressure from Wi-Box unit
Wireless communication with PressureWire Aeris guidewire
+ Enlarge Image
The wireless design of the QUANTIEN integrated FFR system allows you to configure your cath lab environment exactly the way you like – without the clutter of cables.
Easy cath lab installation gives you full FFR integration without cabling through floor or ceiling – and without cath lab downtime.
With the wireless Wi-Box™ unit and PressureWire™ Aeris™ guidewire, the QUANTIEN main unit can be placed as a built-in or mobile device anywhere in the cath lab, freeing up valuable table space and allowing control by either sterile- or nonsterile-dressed staff. PressureWire™ Certus™ guidewire can be used if QUANTIEN main unit is mounted bedside or placed close by the cath lab table on a pole.
QUANTIEN system supports measurement and documentation of both FFR with hyperemia, and Pd/Pa at resting conditions.
With the QUANTIEN system, FFR is always available when and where you want it, without time-consuming setup or cables.
Place it where you want it – on a desktop, on a wall, bedside or on a mobile pole.
Regardless of where you place the QUANTIEN main unit, you can view its video screen on the existing cath lab monitors right next to your angio and hemo screens.
You have fingertip access to all features, using the latest touch screen technology and a high-resolution widescreen.
Quick and easy procedures and full case documentation with DICOM™ Worklist, DICOM Archive, local network and USB memory stick data export.
Ordering Information View Catalog
Contents: QUANTIEN™ Integrated FFR System (1 unit per box)
Power cable (EU, UK, US) (3 units)
Ethernet Patch cable
Note: – Requires AO-pressure from Wi-Box unit (C12783) or via cable with AUX IN cable kit
– Delivered without mounting bracket. Ordered from St. Jude Medical or using third-party standard VESA 75x75 or 100x100 mm mounting bracket.
An FFR measurement above 0.80 indicates normal coronary blood flow and a nonsignificant stenosis. A measurement below 0.75 indicates a high likelihood that a stenosis may be causing ischemia.1
+ Enlarge Image
When integrated into routine lab procedures, measurement of fractional flow reserve (FFR) has been shown to reduce the incidence of adverse events in patients being treated for complex coronary artery disease. Compared to angiography alone, FFR allows physicians to more accurately identify hemodynamically relevant stenoses, reducing rates of death, myocardial infarction and repeat revascularization.2
Key findings from the FAME study show a 28% reduction in major adverse cardiac event (MACE) rates and significant cost savings — without prolonging procedure time.2
Compared to angiography alone, FFR2:
FFR-guided PCI using PressureWire guidewire is a cost-effective strategy that improves outcomes and quality of life compared to medical therapy alone.3,4
1. Pijls NHJ ,et al. N Eng J Med 1996;334;26:1703-08.
2. Tonino PA, De Bruyne B, Pijls NH, et al. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. FAME study. N Engl J Med. 2009;360(3):213-24.
3. De Bruyne B, Pijls N, Kalesan B, et al. Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease. N Engl J Med. 2012;367(11):991-1001.
4. Fearon F, et al. Cost-Effectiveness of Percutaneous Coronary Intervention in Patients With Stable Coronary Artery Disease and Abnormal Fractional Flow Reserve (FAME 2). Circulation. 2013;128:1335-1340.
Please review the Instructions for Use prior to using these devices for a complete listing of indications, contraindications, warnings, precautions, potential adverse events and directions for use.
PressureWire™ Aeris™ and PressureWire™ Certus™ guidewires, QUANTIEN system and Wi-Box™ unit are designed, developed and manufactured by St. Jude Medical. Product referenced is approved for CE Mark.
QUANTIEN system is indicated to provide hemodynamic information for use in the diagnosis and treatment of patients that undergo measurement of physiological parameters with PressureWire guidewire.
QUANTIEN system is intended for use in catheterization and related cardiovascular specialty laboratories to compute, and display various physiological parameters based on the output from one or more electrodes, transducers or measuring devices.
The device has no patient alarm functions. Do not use for cardiac monitoring.


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Amg grell <3
His flaming red hair is gorgeous!
Very beautiful pictures
I really need to get my hair fixed... *needs to fix his red hair, roots are showing* and get glasses. Sheesh this pic is reminding me what I need to do irl. XD
I prefer Grell with his long, crazy hair, but this is great!
wow *Q*
this is so awesome <3
and I really like it how you colored it <3
this is so awesome <3
and I really like it how you colored it <3
Wow beautiful!
Looks so realistic *wanna touch* Nice job!
I like Grell with shorter hair. Awesome job!
absolutely beautiful, then again, that's Grell for ya ^_^
wooooooooo,amazing,like you did, this great. really
ehehehehhehehe >
Damn thats cool
Love the hair. How do you get it to look so red?
Oh wow, this is really good. I really like the face/hair. You did a really good job.
lo Hear is Amazing !


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Comic book readers talk movies' effect on industry
Comic book enthusiasts shopping at Fourth World Comics in Smithtown talk about the impact the motion picture industry is having on the comic book scene, specifically the increased interest there is to read more about some of their favorite characters. Videojournalist: John Paraskevas (April 26, 2013)
Newsday.com now uses Facebook for our comment boards. Please read our guidelines and connect your Facebook account to comment.
Kickboxing class hosts "Shred Your Ex" event Justice Antonin Scalia dies at 79 Lawyer: Shannan Gilbert may have been strangled Officials: Plane fire reported at LI airport DOT: Southern State reopens after accidents in Suffolk Forecast: 'Dangerous' windchill likely for weekend Puppy of the day: Lulu Disabled woman rescued from Eatons Neck house fire Inside the last trailer park in Nassau Long Island myths and legends Christopher McGrath launches State Senate bid Royal Caribbean's Anthem of the Seas returns to port


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You were stirring the soup, your coat sitting on the chair, ready to go get your kids from school when you heard the front door open and close and two soft voices, one of them you identified as Matthew. The scent of softly simmering soup filled the house, wafting through the huge rooms, calling ___'s family to the kitchen doorway. You stuck your head around the corner
"Matt!?" you exclaimed as he ran to you and hugged your legs.
"What are you two doing here...?" Arthur asked, Slightly baffled as to how they got home so quickly by themselves.
"___-san..." an unfamiliar yet gentle voice called. You glanced up wondering who the soothing voice belonged to. A young man stood there. He had brown eyes and strangely familiar black hair.
"Who is he?" you asked
"It's Big Brother Kiku!!!" said Alfred
"K-Kiku...!? When did you grow up to be that big!?" Arthur questioned
"There's nothing to get shocked about, Arthur-san. When I woke this morning, I just found myself this big" Kiku explained
"And the other Asians...?" you asked curiously
"Yes, They grew up too, except for Korea-kun"
"Let's take a seat" Arthur proposed
"So... Did you become independent?" you asked
"Did the panda-freak get angry?"
"I don't think so, but he looked so happy"
"Huh? Is he happy because the number of people in his house decreased?" you teased
"___-san, I never knew you were that childish" he giggled
you chuckled "And by the way, It's my first time hearing the word 'san'... What's that? And what's the name of your country?"
"'San' is an honorific, My country? Nihon desu"
"N-Nihon desu?"
"Oh, I mean Japan"
"Arthur-san, ____-san, Sorry for being rude but, I noticed... Why you two aren't not talking to each other?"
"F-Forget about that! Let's eat?" you immediately changed the subject, you called Matthew and Alfred. You guys started to eat with an unsociable atmosphere.
"Mama! Papa! I got a perfect score earlier!" Alfred boasted as he shoved a laden soupspoon in to his mouth.
"Really? Awesome!"
"'Awesome'? Are you Uncle Gilbert, Mama?" Alfred asked
"Al, you just copied my answer..." said Matthew while eating the tomato.
"Atleast I got a perfect score right?"
You made conversation with the kids and Kiku, deliberately leaving Arthur out. You still hadn't quite forgiven him for the incident earlier. The main topic of conversation was the newly independent Asian countries. Kiku asked if you would like to come and visit him in his country one day.
Darkness fell without you noticing, your conversation with Kiku was getting more and more interesting. The Asian man had a great number of very interesting things to say, from new ideas for something called Anime, and his previous experiences in China's house.
"Yes, Yao-san looked ready to faint when he saw all of us as grownups!" he glanced at a clock, standing
"___-san, I'll take my leave now, I still must cook."
"Be careful on your way home!"
"I'm not a child anymore..." he pouted and left.
'Not a child anymore... huh? Will Matthew and Alfred grow up that fast too?' to be honest, you're afraid of them growing up, If they grew up, Things like being 'Independent' will come to their minds, you don't want to get separated from them.
Afterwards, you called the two for a sleep and you headed with them to the bedroom.
'Gosh... I feel like an idiot now... I should be apologizing! Not ignoring him!' you cried mentally as you pulled the bedsheets and hide under it. 'How can I make this up to him...?' you sighed. Then you felt strong arms wrap around you waist from behind. You knew just from breathing in that it was Arthur, the scent of tea and the forest clung to him like a second skin. It wasn't unpleasant, quite the contrary
it smelt relaxing, reminding you of spring time and sunshine.
"You're not angry...?" you asked, somewhat shy
"Of course not..."
"Not? But why you're not talking to me...?"
"I want to give you some space, It'll be annoying if I keep talking to you right?" he hugged you tighter "___, Look at me..." you turned around and faced him, When you turned around, he gave you a surprise kiss
"I'll repeat this again, If you're having problems, Don't be afraid to tell me..."
sweet :3
KIKU!!!!! Iggy I'm serious! STAPH GIVING OUT FREE CAVITIES! YOUR TO SWEET! then again…every likes a sweet guy!
KIKU!!!! I dunno who I like best! Japan (who's like a big bro to meh) Or Iggy (of who I have a big crush on) >.<
he half confessed xD
Kiku is seriously adorable!!! And Iggy was sooo sweet!!!
Kiku's grown-up! and the other asians!!! Yaaaay~! and Iggy's so cute!!!
Korea...he'll be young forever...not in a good way...
When I read the part about Kiku grew older... I keep on collapsing
(Kiku's my favorite character in hetalia 2nd place by iggy~ sorry iggy ;^
(Kiku's my favorite character in hetalia 2nd place by iggy~ sorry iggy ;^
Kiku is so adorable!!!! -glances at iggy- o...of course I love you!! (iggy- why am I not convinced?)
Lol. Fail Korea.
*when kiku grew up* WHAT?!? SO FAST!!! O.O
Korea no grow?
Nyaaa~ *pant *pant8.. Nyaaa~~
I will transform to smexy cat at once if i keep up to read this story...
*think a minute*
Well, i'll better keep up of it !!
I will transform to smexy cat at once if i keep up to read this story...
*think a minute*
Well, i'll better keep up of it !!
fan girl squealing
mum: TIA STOP BLOODY SQUEALING!
mum: TIA STOP BLOODY SQUEALING!
Wow, so the Asian nations are grown up huh, well except for Korea lol~
*sigh* oh iggy. I love you.
Kyuu~... how cute is he >//w//<
ooh Artie your too sweet >.<
*does signature puppy dog eyes* Pwease Continue~
um arthur, if you have to continue to do that just to get me to tell you my problems, i think i need to have more problems. soon i will have so many problems that we will never be separated, i-i think my plan is totally fool proof.
hahaha at least i didn't have a really interesting cliffhanger! But a cliffhanger always a cliffhanger!
Es muy, muy, muy, lindo!!! y no te sientas presionado a escribir rapido, dicen "Quality not Quantity"
Please pardon me I'm jut so very eager - w-
Please pardon me I'm jut so very eager - w-
dude, you NEED to continue this! it's so cute!


text:
Shin Megami Tensei: Persona 4
Question from waxelplax
How do i make an Izanagi with Primal Force Power charge and resist wind?
I'm really bad with fusing so please make the explanations as simple as you can
6 years ago
Accepted Answer
Arthellinus' Formula:
1. Izanagi x Sarasvati (Repel Physical, Null Wind) x Mithra = Legion (Repel Physical) <== saved Legion
2. Lachesis (Absorb Wind) x Sarasvati = Orthrus (Absorb Wind)
3. Orthrus (Absorb Wind) x Slime = Matador (Absorb Wind)
4. Matador (Absorb Wind) x Mokoi = Ghoul (Absorb Wind)
5. Ghoul (Absorb Wind) x Orobas x Pixie = Obariyon (Absorb Wind)
6. Legion (Repel Physical) x Obariyon (Absorb Wind) = Yomotsu-Shikome (Repel Physical, Absorb Wind) <== saved Yomotsu-Shikome
7. Ardha (Primal Force, God's Hand) x Queen Mab = Siegfried (Primal Force, God's Hand)
8. Siegfried (Primal Force, God's Hand) x Forneus = Flauros (Primal Force, God's Hand)
9. Flauros (Primal Force, God's Hand) x Yomotsu-Shikome = Ares (Primal Force, God's Hand)
10. Ares (Primal Force, God's Hand) x Sarasvati (Repel Physical, Null Wind) = Ose (Primal Force, Power Charge, Null WInd)
11. Ose (Primal Force, Power Charge, Null Wind) x Legion (I had better noise filtering on him vs Shikome) = Obariyon (Primal Force, Power Charge, Null Wind)
12. Obariyon x Yomotsu-Shikome
6 years ago
This question has been successfully answered and closed
More Questions from This Game
|Whats the difference between Gods hand an primal force?
|What do Mind Charge and Power Charge do, exactly?
|Can and how i make izanagi with victory cry?
|IS there someone who can help me make izanagi with better or good skill??
|How can I make a good custom Izanagi? ( simple answers please)


text:
From Backcountry to Breadbasket to Battlefield -- and Beyond
The Shenandoah Valley invites you to learn about its rich heritage, from Native Americans who first shaped the land, to pioneers of this frontier; this fertile area became one of the most important wheat producing regions of the entire South. The Valley also witnessed some of the most dramatic events of the Civil War,including the Battle of Cedar Creek, a decisive October 19,1864 Union victory.
Ranger Programs
Find out about the many events we are offering throughout the park. Also meet our interpretive staff. We look forward to your visit!Read More
Stories about the Shenandoah Valley History
Read the many stories that tell the history of the Shenandoah Valley. Learn about the early geology, natives, settlement, age of grain, and Civil WarRead More
Multimedia and Social Media
Check out the Cedar Creek Battle App or join the park dialogue and connect with us on Facebook or Twitter.Read More
Self Guided Battlefield Tours!
Drive the footsteps of October 19, 1864 with your choice of a self guided driving tour, battle app for Iphone and Android, or podcost tour.Read More
Become a VIP (Volunteer in Parks) at Cedar Creek and Belle Grove NHP!Read More
A Partnership Park
Cedar Creek and Belle Grove NHP, a "partnership park," in which the National Park Service works with Key Partners to create and manage the park.Read More
Trading Cards for Kids
Discover more than 500 stories about America's journey from the Civil War to Civil Rights. View online or visit this park to collect your own copies.Read More
Visit the National Civil War site
From 1861 to 1865, the American union was broken as brother fought brother in a Civil War that remains a defining moment in our nation's history.Read More


text:
|http://ghr.nlm.nih.gov/ A service of the U.S. National Library of Medicine®
The official name of this gene is "age-related maculopathy susceptibility 2."
ARMS2 is the gene's official symbol. The ARMS2 gene is also known by other names, listed below.
The ARMS2 gene provides instructions for making a protein whose function is unknown. Studies suggest that the ARMS2 protein is found primarily in the placenta and in the specialized light-sensing tissue in the back of the eye (the retina). However, it is unclear what role, if any, the protein plays in early development or normal vision.
The ARMS2 gene is located on the long (q) arm of chromosome 10 in a region known as 10q26. This region has been strongly associated with the risk of developing age-related macular degeneration, a common cause of vision loss in older adults. Researchers have identified several variations (polymorphisms) in and near the ARMS2 gene that may explain the association between the 10q26 region and age-related macular degeneration. The best-studied of these variations, known as rs10490924, alters a single protein building block (amino acid) in the ARMS2 protein. Another common variation, a complex change that deletes a segment of the ARMS2 gene and inserts new genetic material, may also contribute to disease risk.
It is unclear how polymorphisms in the ARMS2 gene might be related to age-related macular degeneration. In the 10q26 region, the ARMS2 gene is located next to a gene called HTRA1; changes in this gene have also been studied as a risk factor for the disease. Because the two genes are so close together, it is difficult to tell whether changes in one gene or the other, or possibly changes in both genes, account for the increased disease risk. Age-related macular degeneration is a complex condition that likely results from a combination of multiple genetic and environmental factors.
Cytogenetic Location: 10q26.13
Molecular Location on chromosome 10: base pairs 122,454,663 to 122,457,352
The ARMS2 gene is located on the long (q) arm of chromosome 10 at position 26.13.
More precisely, the ARMS2 gene is located from base pair 122,454,663 to base pair 122,457,352 on chromosome 10.
See How do geneticists indicate the location of a gene? (http://ghr.nlm.nih.gov/handbook/howgeneswork/genelocation) in the Handbook.
You and your healthcare professional may find the following resources about ARMS2 helpful.
You may also be interested in these resources, which are designed for genetics professionals and researchers.
See How are genetic conditions and genes named? (http://ghr.nlm.nih.gov/handbook/mutationsanddisorders/naming) in the Handbook.
amino acid ; chromosome ; epithelium ; gene ; pigment ; placenta ; protein ; retina ; susceptibility ; tissue
You may find definitions for these and many other terms in the Genetics Home Reference Glossary.
The resources on this site should not be used as a substitute for professional medical care or advice. Users seeking information about a personal genetic disease, syndrome, or condition should consult with a qualified healthcare professional. See How can I find a genetics professional in my area? (http://ghr.nlm.nih.gov/handbook/consult/findingprofessional) in the Handbook.


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