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Biarritz Convenience BI321
From $108 / night
balance due
Description from the manager
Description from the manager
Bedrooms: 1/
Bathrooms: 1/
Sleeps: 2/
Type: Apt. / Condo
Just bring your toothbrush, and enjoy all the comforts of home. You|ll save on your Palm Springs vacation with this condo. This community boasts an Olympic pool, spa tennis courts and is within walking distance to the downtown area. Reserve yours today.
This charming one bedroom, one bath, second floor condo at the Biarritz has traditional furnishings. The condo has a king bed in the master bedroom and a convertible sofa that pulls out into a bed in the living room.
For enjoyment, it has two TVs, a DVD player, and a stereo system. There are two balconies facing the east, perfect for catching the early morning sunrise!
The many amenities of the ...Read more
About the manager
About the manager
Oranj Palm Vacation Homes
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text:
Our Club Teams
Girls Team Pages
Boys Team Pages
Adult Men's Team Pages
Age groups reflect the
2015/2016 soccer year
Please refer to our age group chart above to verify your child's age group.
For our recreational teams & clinics, visit the 'Programs' area.
The teams at left are our club teams. To learn about "club soccer" and how it differs from recreational ('in-house') and travel programs, visit HERE.
Current Tryout News
Visit the tryout page HERE for a list of teams with current needs and to learn about annual tryouts.

subset: commoncrawl


text:
State Police Can Relocate Witnesses in Gang Trials
Janota, Laura, Daily Herald (Arlington Heights, IL)
Byline: Laura Janota Daily Herald Staff Writer
Witnesses who inform on street gangs in Illinois now can receive special protections because of a law Gov. Jim Edgar signed Thursday.
An 18-month, $1 million pilot program that primarily would relocate witnesses and victims of gangs now will be administered by the Illinois State Police.
Through the program, county prosecutors and the Illinois Attorney General's office would be eligible for grants for relocations, name changes and other witness protection purposes.
"State prosecutors told us over and over that they really have no way to adequately protect witnesses," said Illinois Attorney General Jim Ryan of Bensenville.
Ryan, who led the governor's Commission on Gangs, said there's no way to know yet how many informants, witnesses and victims will need or receive protection through the new program.
The program is needed most in downstate counties that have budgeted little money for witness-protection purposes, he said.
The law Edgar signed from the Commission on Gangs, also will:
- Establish a Street Gang Criminal Drug Conspiracy law that carries mandatory sentences of up to 60 years for gang leaders convicted of major drug dealing. Current maximum penalties are up to 30 years. …


text:
Things to Do in Mooloolaba
Here you can find out things to do around Mooloolaba and the Sunshine Coast.
Holidaying on the Sunshine Coast with kids
The Sunshine Coast is a children's wonderland. With theme parks, plenty of fun filled events, shows, kids programs and more throughout the year the Sunshine Coast is perfect for visiting with children. Aussie World, Australia Zoo, UnderWate.. Read More
Health and Vitality abound in Mooloolaba
Staying healthy on your holidays is effortless on the Sunshine Coast. The climate, scenery and culture all inspire a happier, healthier you. We're not suggesting you fill every minute with sweaty pilates classes, tasteless kale smoothies or.. Read More
Experience swimming with the Whales in Mooloolaba
One of the reasons our clients love staying with us at Oceans Resort is because we are located in an ideal position on Mooloolaba Esplanade, just opposite the beach. Our 5 star luxury apartments (http://www.oceansmooloolaba.com.au/luxury-accommod.. Read More
Seafood in Mooloolaba and The Best Way To Eat Crab - (catch it fresh)
At Oceans Resort, our clientele spend their holidays in our luxury beachside apartments (http://www.oceansmooloolaba.com.au/luxury-accommodation.html) for many reasons. One reason is because they want to relax and rejuvenate themselves in the pri.. Read More
The Best Sunshine Coast Cooking Schools - Spirit House & Tamarind (Spicers)
If your idea of a relaxing, Zen like holiday is to stay in a luxury, beachside resort in a private and spacious apartment then we have everything you need at Oceans in Mooloolaba. If you also like the notion of spending part of your h.. Read More
Holiday Time: Things to do for Kids in Mooloolaba
Family is an important part of the Australian lifestyle and taking time out of your busy life, to visit relatives on the Sunshine Coast helps to rejuvenate your mind and feed your soul. There are lots of things to do in Mooloolaba (http://www.oce.. Read More
World Heritage Discovery - Fraser Island
The Sunshine Coast has something for everyone, from lazy weekend getaways to well-deserved, week long family holidays. Whether you want to spend a day up in the Hinterland, just potter around close to your Mooloolaba beach resort or break out and.. Read More
Best beach spots in and around Mooloolaba
The Sunshine Coast has some of the best beaches in Australia and many are just a short stroll or a quick drive from your Mooloolaba apartments (/luxury-accommodation.html). It is fair to say that with our fabulous sunny weather and pristine beach.. Read More
Learn a New Skill in Mooloolaba - Stand up Paddle Boarding, Surfing, Kayaking...
Spring is a wonderful time of the year at Mooloolaba, lending itself well to spending countless hours pottering around our designer boutiques and brunching with family and friends. Maybe you could laze away a few hours or even a whole day sunbaki.. Read More
Boutique Shopping in Mooloolaba - Essential Beach Wear and Gifts
With the weather warming up, it feels like we are racing towards summer once again, and thoughts of weekends away and beautiful lazy holidays at the beach become even more compelling. Mooloolaba is one of those places that gets under your skin, w.. Read More
Beautiful Nature Walks on the Sunshine Coast
The Sunshine Coast is a haven for hikers, but you don't have to be a diehard to enjoy all that the Sunshine Coast has to offer. When you stay at Oceans Resort in Mooloolaba, there are lots of great beach walks and walking tracks that are su.. Read More
Local Markets and fresh produce on the Sunshine Coast
With fabulous year round weather and great surfing beaches, Mooloolaba has become a favourite holiday spot for locals and visitors alike. Another reasons that locals, in particular, come here is because of the fabulous local produce markets on th.. Read More
The Best Fine Dining in and around Mooloolaba
Holiday time is a great excuse for indulging yourself and taking advantage of some fine restaurant dining. So it's good to know that some of the best restaurants in Mooloolaba are not far away from your Ocean's luxury accommodation. F.. Read More
Café Society - Espresso Discoveries in Mooloolaba
One of the great pleasures in life is a really good cup of coffee. Add to this the friendly ambiance of a local coffee house and some warm, sunny weather – and you have the makings of a wonderful, relaxing afternoon. So if you are a co.. Read More
The Best Cocktails and Sundowners in and Around Mooloolaba
There are many ways to end a relaxing day on the Sunshine coast, but one of the most enjoyable is to seek out the best cocktails in Mooloolaba. And the secret to finding these little gems is to go where the locals go. With some insider knowl.. Read More
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Friday, February 12, 2016
It's the Bowery Boys again, in their 35th feature film. Sach (Huntz Hall) buys a battered oil lamp, which turns out to have belonged to Aladdin some 2000 years earlier. Out pops a genial genie (Eric Blore), who grants every wish of Sach and his pal Slip (Leo Gorcey). Gangsters steal the lamp, but discover that the genie won't grant any wishes unless Slip and Sach tell him to, so the baddies snatch Our Heroes as well. The boys escape by insisting that the genie take them home. He does--to his home, ancient Baghdad. Slip and Sach barely escape the scimitar of the angry Caliph; they return to the Bowery minus the genie but with their heads intact. In typical Bowery Boys fare, this entry is pepped up by the appearance of veteran comic actor Eric Blore in his final screen appearance. ~ Hal Erickson, Rovi


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Luck Plus is a unique card and dice game of number matching. This game is for 2 to 8 players, ages 7 and up. It comes with 108 cards, 2 dice, and instructions. The cards are divided out as follows:
48 GO cards - 4 set, of Green cards 1 through 12
22 STOP cards - 1 set of red cards 1 through 12.
1 set of red cards 1 through 10.
20 TRANSFER cards - 1 set of yellow cards 1 through 12.
1 set of yellow cards 5 through 12.
4 TRANSFER PLUS cards - 1 set of yellow cards 1 through 4.
6 DOUBLES cards
8 LUCK PLUS cards
The object is to be the first player to eliminate all of your cards by matching cards and dice. Each player is dealt 8 cards face up. The remaining cards are stacked face down in the center of the table to form the draw pile. The top card of the draw pile is turned face up and placed next to the draw pile to form the match pile. Each player will then try to get rid of as many cards as possible by matching the numbers on the cards with the numbers on the dice they roll. There's a bit more to it than that, but you'll have to see the rules to get the whole picture.
This is an amazing and fairly complex game that has many interesting and unique aspects if you can wander through the somewhat confusing rules sheet that comes with the game. As noted before on the site, this game is a 'press your luck' style game that is steeped in probability and pivotal choices.
Things that set this game apart from others:
-- The cards are dealt face-up for all to see. No reneging or possibilty for someone to peer into someone's hand. (Because the cards are face-up, I actually wrote a computer game that plays this game flawlessly, but it's in an archaic language. Hmmm.)
-- The Transfer cards in the game make each of the players somewhat involved even though it's not their turn. (We played that plain transfer cards could be transferred to anyone, not just the next player.)
-- The game is similar to craps - one of the most exciting casino games out there. It's also similar to the old High Rollers game show bonus game or he solitaire dice game Shut the Box.)
-- There is a decided cut-throat aspect to the game with the rule variation above makes for a contentious game where the leader is never safe.
-- Your dice roll can be used by the following players. This may change your strategy dramatically.
-- And if you're a numbers and probability geek like me, this game seems to spark a new strategy every time you play.
Over the years, we've instituted may variations that are not on the official rules sheet. I may post these in the future.
Ebay has this game for sale almost all the time. Many of the games are barely used as the game seemed to be too confusing for most kids who loved UNO. I have six copies of the game and consider this the best game ever if you want to see the improbable happen!
Our record for consecutive plays (where you can either make a match or make a successful draw) without busting is 16. Insanity! :^)
And I once rolled a 2, 11, and 12 consecutively to win a game. The odds of that are almost 3000 to 1. Of course, we've probably played 3000 games. :^)


text:
Hotels around
Plaza Palace Hotel Quick description Conveniently located on the main pedestrian street of Varna,...
Plaza Hotel Hotel information Plaza Hotel features 14 studio-lux, 7 standard rooms and 6...
Hotel Perfect Quick description Situated in the very heart of Varna and only 200 metres from...
Art Deco Hotel Odessos Quick description Varna's Hotel Odessos is located just 100 metres from the...
Astra Family Hotel Quick description Astra Family Hotel is located in Varna's centre, 800 metres...
mOdus Hotel Quick description The unique mOdus Hotel in Varna is a stylish property with an...
Best Western Prima Hotel Hotel information Our hotel was totally refurbished in February 2008 and now...
Graffit Gallery Design Hotel Quick description This modern 5-star hotel is located in the centre of Varna,...
Reverence Hotel Quick description In the business and administrative district of Varna,...
Capitol Hotel Quick description Located next to the Sea Garden in the centre of Varna,...
Interhotel Cherno More
|Interhotel Cherno More
|33 Slivnitca blvd.
|9000 Varna City
|show map
The Interhotel Cherno More is located in the centre of Varna and offers air-conditioned rooms with free WiFi and panoramic views. The beach is located 450 metres away and the Sea Garden can be reached in 300 metres. Each features a TV with cable channels, and a refrigerator. Some rooms are equipped with a seating area with a sofa. The en-suite bathroom comes with a shower, free toiletries and a hairdryer. A fitness centre, a casino, various restaurants, a cocktail bar with panoramic views, shops, a bank and many more facilities are available on site. The top-floor restaurant offers scenic panoramic views. Additional sports and entertainment options include a yoga and a dance studio. Bowling and billiards are available as well. Varna Train Station can be reached in 2 km, while Varna Airport is set 10 km away. Many of the historical and cultural show places in Varna can be reached within a 10-minute walk from the hotel - the Opera, the Art Gallery and the Archaeological Museum.
Photo album
Located in Varna City, 400 metres from Varna City Hall, Interhotel Cherno More features air-conditioned rooms and private parking. The hotel has a terrace and fitness centre, and guests can enjoy a meal at the restaurant or a drink at the bar. The rooms are fitted with a private bathroom. Extras include free toiletries and a hair dryer. Interhotel Cherno More features free WiFi throughout the property. A flat-screen TV is featured. You will find a 24-hour front desk, hairdresser's, and shops at the property. You can play billiards at the hotel. The hotel also offers car hire. Varna Central beach is 500 metres from Interhotel Cherno More, while Varna Opera House is 700 metres away. The nearest airport is Varna Airport, 8 km from Interhotel Cherno More.


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The Circus Comes to Town
I'll admit it I fit the cliche, as a kid I was always excited when the circus came to town. It was a special treat to go. I remember going a couple times as a kid and then one time when I was a bit older and my younger brother was the little guy. Then came the time when I worked in the building next to where the circus was performing and the smells of the circus weren't quite so magical!
My favorite performers to this day remain the trapeez artists. I find them mezmorizing. What they do high up there in the air, is to me absolutely amazing!
Circus Wednesday, Nov. 3, 9pm on WOSU TV
CIRCUS goes behind the scenes to follow the lives of the performers and crew of the Big Apple Circus during the 2008-2009 touring season. It's a fascinating inside look at all aspects of the circus.
If you'd like, you can participate in a special live chat with the CIRCUS filmakers, Maro Chermayeff and Jeff Dupre. On Thursday, November 4, at 2:00pm (EST) click on the link above or head to http://www.pbs.org/opb/circus/interact/filmmaker-chat/ to find out what is was like making the film and to talk to some of your favorite cast members.
Enjoy the CIRCUS airing the next three Wednesday nights at 9pm on WOSU TV.
Stacia H.


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Raturdae Multi-shot by Steph-LaberisWatch
©2013-2016 Steph-Laberis
DONE! A felted Raturdae, based off of my illustration from last year. I am in love with the little white guy and I am sad to see him go to the gallery - I hope they get a good home!
Daily DeviationGiven 2013-04-11
The suggester said: "*Steph-Laberis's Raturdae Multi-shot displays gorgeous needle felting work that brings her original illustration to life in the most gorgeous way possible. The design, balance, composition and execution of this piece is brilliant." ( Suggested by cakecrumbs and Featured by Talty )
Wow this is amazing!! I love your original illustration but to see them felted... what a beautiful piece!
I love everything about this piece, but my favorite part is how the white rat is balancing the cherry on its nose!
so cute))
This is really sweet! Looks a lot like the drawing
I absolutely adore this, i am always in awe of people who can work in 3D mediums. And felting fascinates me too. The little faces on the rats and over all character is so cute and charming.
wow ! these are so cool! I am amazed!
I saw him at the gallery today and I was surprised it was the same gallery. I started freaking out how cool it looked in real life.
Oh, that makes my day to hear! Thank you! How did the show look? I wish I could have taken time off to check it out in-person, I saw some KILLER stuff on the show's preview list!
It looked so well done and bigger than I expected. I loved it. I couldn't afford it but I wouldn't be able to appreciate it as well as others did. I saw people taking pictures like I was. A few artists even showed up. There was even a DJ there. I hope to see your stuff next year and congrats on the DD! Maybe getting into the gallery was good luck for you.
wow amazing!
Cute and so creative
Congrats on the DD. I have seen a few of your works and well worthy of this for interesting piece of work. Different an eye catching.
OMG! This is more than amazing to me. My wife and child have two rats, just like these too, and the white one, Snow (also known as Tubby, for obvious reasons) is the food stealer/hogger of the two. This depicts them so well. The illustration and the felt dolls are very well done. Great concept, excellent job.
Cheese and crackers this is nothing short of amazing. Love the poses and expressions. Really creative idea and fantastic execution.
Congrats on the DD!
so cute >w<
What a cute little sundae rat!
so cute!!!!!!!!!!
the white one's smile really is adorable
Adorable and beautiful work! I can't help but love it! thanks for sharing something this sweet
god i love this movie so much, and this and you are amazing
Is very adorable!!
awww they're so cute
They are super lovely!
This is one of the most unique things I have seen in a really long time. So cute and so well done. I am just crazy about it!
That's adorable! How did you make this? I know it's felt but the shapes are all so perfect and round!
Thanks! I made this by needle felting, it's not at all like sewing and much more like sculpting, so you can get seamlessly round shapes easily. It just takes time!
Aww at first glance I thought they we're Ice cream scoops ;v; This is so adorable and creative <3
Congratulations on the totally awesome Daily Deviation! Your work deserved it! ♥
oh my .... this is so cute! CONGRATS on the DD.
- Congrats on the well deserved DD!
Have a nice day!
o my! what an adorable piece of candy they are gorgeous! congratulations on the DD too!
Yay, I'm happy to see these awsome guys got a DD. Well done and well deserved!
Congrats on the Daily Deviation!
Is a raturdae what you eat on Caturday??
Wow! These are easily a couple of the most whimsical and just plain appealing pieces I've seen done in needle-felting, which is a method of sculpting I really admire. Wonderful work! They'd be marvelous in any medium, but seem especially well-suited to this one.
Oh, and congrats on the DD!
Oh, and congrats on the DD!
AWWW wonderful. Yep, the white one is perfect!
Oh those little rats are so sweet!
They make me happy
I absolutely love how you did the swirls on that one rat's back and their characterizations are so perfect! <3 I wish I could go see them at the gallery, but it's across the country ;A;
I love the swirls and the white rats smiley little face Amazing!
this is so cute and it looks just like your drawing. Amazing and adorable
Amazing! They look so awesome and are super adorable!
If it were economical of your time to make them, I bet these could be sold as displays to ice cream parlors.
Looks just like the picture!,You have a real knack for this Steph!


text:
Administrative Delays as Barriers to Trade
One domestic firm and one foreign firm must decide when to introduce their new product to the home market. The home government may apply an import tariff, an administrative delay, or both to the product of the foreign firm. We show that, while both the tariff and administrative delay can ensure the socially optimal timing of entry, the administrative delay is the less efficient instrument for maximising home welfare. If trade liberalization constrains the import tariff to be below its domestically optimal level, we show that the optimal administrative delay leads to lower levels of world welfare than the optimal tariff, so that trade liberalization can be welfare decreasing.
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|Date of creation:
|28 Jun 2003
|Date of revision:
|Contact details of provider:
| Postal: Wivenhoe Park, COLCHESTER. CO4 3SQ
Phone: +44-1206-872728
Fax: +44-1206-872724
Web page: http://www.essex.ac.uk/economics/
More information through EDIRC
|Order Information:
| Postal: Discussion Papers Administrator, Department of Economics, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, U.K.
References listed on IDEAS
Please report citation or reference errors to , or , if you are the registered author of the cited work, log in to your RePEc Author Service profile, click on "citations" and make appropriate adjustments.:
- Miyagiwa, K. & Ohno, Y., 1993.
"Closing the Technology Gap Under Protection,"
Working Papers
93-09, University of Washington, Department of Economics.
- Miyagiwa, Kaz & Ohno, Yuka, 1995. "Closing the Technology Gap under Protection," American Economic Review, American Economic Association, vol. 85(4), pages 755-70, September.
- Miyagiwa, K. & Ohno, Y., 1993. "Closing the Technology Gap Under Protection," Discussion Papers in Economics at the University of Washington 93-09, Department of Economics at the University of Washington.
- Prokop, Jacek & Regibeau, Pierre & Rockett, Katharine, 2009.
"Minimum quality standards and novelty requirements in a one-shot development race,"
Economics Discussion Papers
2009-33, Kiel Institute for the World Economy.
- Prokop, Jacek & Regibeau, Pierre & Rockett, Katharine, 2010. "Minimum quality standards and novelty requirements in a one-short development race," Economics - The Open-Access, Open-Assessment E-Journal, Kiel Institute for the World Economy, vol. 4, pages 1-49.
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text:
Manik Sarkar calls on Narendra Modi
Posted on Aug 08 2014 | IANS
New Delhi/Agartala, Aug 8 : Tripura Chief Minister Manik Sarkar Friday called on Prime Minister Narendra Modi in New Delhi.
"It was a courtesy call," an official of the Chief Minister's secretariat told IANS in Agartala.
Sarkar, also a politburo member of the Communist Party of India-Marxist (CPI-M), skipped the swearing-in ceremony of Modi as prime minister in New Delhi May 26.
Tripura's Health and Family Welfare, Revenue and Public Works Minister Badal Chowdhury, also a CPI-M central committee member, represented the Left Front government at the swearing-in ceremony.
Sarkar had said he will meet Modi after some time to raise the issues concerning Tripura.
Sarkar is in New Delhi to attend the three-day CPI-M central committee meet that began Friday.


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silly prints by peteandbobWatch
©2008-2016 peteandbob
21 shoe and foot prints. I thought that since deviant art doesn't have very many "prints" that I'd make up a brush pack. I included a lot of different styles of shoe for those who want them.
Hope you like. please comment if you do.
Hope you like. please comment if you do.
Awesome!!! Just what I was looking for...I'll share my final creation
Thanks! I needed some pieces and inspiration. This helps.
thanks! i really needed this
Woot! I needed these somethin' awful! thank you!
sorry they are all pink on the image.. you can change the colours up.. but i was playing with pink. LOL


text:
Top Definition
In the sexual sense, an "ass licker" is anyone who enjoys licking someones asshole.
po Steve - Buffalo NY Август 20, 2003
1. an admirer of someone in a (more) powerful position.
2. an extreme supporter who gives attention and affection to a person who is already on a pedestal or otherwise popular.
2. an extreme supporter who gives attention and affection to a person who is already on a pedestal or otherwise popular.
They protest the government when Obama is in office, but when it was Bush in the White House, the Tea Partiers were some of the government's most dedicated asslickers.
po D.S. Credito Март 4, 2015
Someone who participates in licking of ass.
Man ryan Francis is such an ass licker!
po AK Април 2, 2003
Someone who is sexually stimulated and gratified by licking another persons filthy, stinky asshole.
That dude is a bonified Ass Licker. He licked his girlfriend's asshole clean. He even ate the kernal of corn she farted onto his tounge.
po slicksal Октобар 23, 2006
1. A person or persons who are constantly licking someone elses ass so they can get something in return. Often used to describe teachers pets and people who suck up constantly.
2. Jason Drury
2. Jason Drury
1. You're such an ass-licker Jason that it is impossible to tell where you start and the teacher ends.
po Scott Williamson Јун 18, 2004
A redneck fucker from Jacksonville who sits in front of me in Math class and always kisses the teachers ass just so he can fuck her while her husbands out cheating on her with some man-whore.
That ass licker fucked our 84 year old History teacher last night...
po Anonymous Мај 7, 2004
One who licks ass because he or she sucks so bad. Also, an ass kisser who is such a loser that he or she must lick the ass they are kissing.
Yo dude, JEML1754 is suck an asslicker, he wants us to call him "asslicker"
po Jon Март 13, 2005


text:
Are you Ling Zhou?Claim your profile
Publications (40)10.75 Total impact
Article: [Construction and immunological responses of recombinant adenovirus containing Epstein-Barr nuclear antigen 1 in mice][Show abstract] [Hide abstract]
ABSTRACT: This study aimed to construct recombinant adenovirus expressing Epstein-Barr nuclear antigen 1 (EBNA1) against nasopharyngeal carcinoma (NPC). The C-terminal region fragment of the ebna1 gene of Epstein-Barr virus was amplified from the standard strain B95-8 by polymerase chain reaction (PCR). The gene fragment was inserted into the pDC316 shuttle plasmid using the EcoRI and BgIII restriction enzyme sites. The pDC316-ebna1 shuttle plasmid and pBHG helper plasmid were cotransfected into HEK293 cells after sequencing. The soluble protein was extracted from HEK293 cells, which caused apparent cytopathic effects. The transcription and expression of the ebna1 gene were confirmed using flow cytometry and Western blotting. rAd-ebna1 titers were measured by the TCID50. rAd-ebna1 was injected into BALB/c mice at a dose of 2 x 10(8) VP per mouse, EBNA1 epitope-specific responses were measured at 1st, 2nd, 4th and 8th weeks post-immunization. The target fragment of ebna1 (939 bp) was obtained by PCR, and was in consensus with the sequence from the standard strain B95-8. Cytopathic effects were observed after the pDC316-ebna1 shuttle plasmid and pBHG helper plasmid were cotransfected into HEK293 cells. rAd-ebna1 was successfully recombined in HEK293 cells. EBNA1 protein was detected in HEK293 cells, rAd-ebna1 titers reached 10(8) TCID50/mL. Specific responses to CD4+ epitopes of EBNA1 were detected in the immunized mice. In conclusion, rAd-ebna1 was successfully constructed and induced specific responses to CD4+ epitopes of EBNA1 in immunized mice.
Article: [Laparoscopic conservative surgery plus gonadotropin-releasing hormone agonist in the treatment of endometriosis: a meta-analysis][Show abstract] [Hide abstract]
ABSTRACT: To evaluate the efficacy of laparoscopic conservative surgery plus gonadotropin-releasing hormone agonist (GnRH-a) in the treatment of endometriosis through meta-analysis. Six randomized controlled clinical trials comparing laparoscopic conservative surgery plus GnRH-a versus placebo or no treatment for endometriosis were retrieved. Meta-analysis was conducted to estimate the efficacy. A total of 477 patients were included. Among them, 233 patients received laparoscopic conservative surgery plus GnRH-a while another 244 laparoscopic surgery alone. The results of meta-analysis showed that laparoscopic conservative surgery plus GnRH-a could decrease the recurrence of pain symptoms (P < 0.05), but it could not increase the pregnancy rate of infertility associated with endometriosis (P > 0.05). Furthermore the combined regiment could better improve clinical symptoms than placebo. Laparoscopic conservative surgery plus GnRH-a could decrease the recurrence of pain symptoms associated with endometriosis, but it failed to increase the pregnancy rate of infertility.
Article: Synergistic Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin and N-nitrosodiethylamine on Cell Malignant Transformation[Show abstract] [Hide abstract]
ABSTRACT: The present paper aims to investigate the effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and N-nitrosodiethylamine (DEN) on tumorigenesis and its potential mechanism. The potentials of TCDD and DEN in separation or in combination to induce malignant transformation were tested in Balb/c 3T3 cells by using a cell transformation assay method. The possible mechanism of observed effects was studied further by adding α-naphthoflavone (α-NF), a competitive binding agent of TCDD, to the Aryl hydrocarbon receptor (AhR) pathway. The mRNA expressions of Cyp1a1 and Cyp2a5 gene in Balb/c 3T3 cells treated by DEN and TCDD in separation or in combination with or without presence of α-NF were measured with fluorescence quantification RT-PCR technique. The cell transformation frequency (TF) was significantly higher in case of induction with TCDD in combination with DEN, as compared to that with either TCDD or DEN alone. These effects were not inhibited via α-NF. The mRNA expression levels of both Cyp1a1 and Cyp2a5 were enhanced by TCDD treatment alone, but this inducible effect was blocked in cells treated by TCDD and DEN in combination. TCDD and DEN had a significant synergistic effect on tumorigenesis when they were used in combination. AhR pathway may not be the key mechanism of this synergistic effect. Thus, it is necessary to further test the potential mechanism involved in cancer development.
Article: Application of proteomic models for the diagnosis of inflammatory and non-inflammatory preterm delivery[Show abstract] [Hide abstract]
ABSTRACT: To establish the serum proteomic models for the identification of premature delivery with inflammation or non-inflammation. The laboring patients from 2008 to 2010 at our hospital were divided into 5 groups according to placental pathology, including inflammatory preterm group, non-inflammatory preterm group and blind test group (n = 50 each). The control group was normal full-term. The preterm models with or without inflammation were established by the methods of SELDI-TOF-MS (matrix-assisted laser desorption/ionization-time of flight-mass spectrometry) and bioinformatics. And statistical analysis was performed after a blind test. Then differential protein fingerprints were compared and analyzed. A total of 36 different proteins were harvested after a comparison of inflammatory preterm and control groups. The model was established by eight markers. The rates of specificity, sensitivity, positive predictive value and negative predictive value were 80.85%, 84.44%, 93.33% and 46.67% respectively. Fifteen different proteins existed between non-inflammatory preterm and control groups. There were 4 marker proteins. The rates of specificity, sensitivity, positive predictive value and negative predictive value were 75.68%, 64.44%, 80.00% and 66.67% respectively. Different marker proteins existed between the identification models of inflammatory preterm labor and inflammatory full-term. Different serum proteomic models may be used for the diagnosis of preterm labor and the differentiation of preterm labor with or without inflammation. And different proteins are expressed during different stages of pregnancy with chorioamnionitis.
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ABSTRACT: To detect human papillomavirus (HPV) DNA in esophageal carcinoma (EC) 109 cells and investigate the relationship between HPV and EC. Genomic DNA and total RNA from EC109 cells were isolated. HPV DNA was detected by polymerase chain reaction (PCR) with the general primer sets of My09/11 and GP5 +/6 + for the HPV L1 gene and type-specific primer sets for HPV18 E6 and HPV18 E6-E7. Reverse transcription (RT) of mRNA isolated from EC109 cells was performed to produce a cDNA. And then a PCR-based protocol for the amplification of papillomavirus oncogene transcripts was used to analyze HPV18 DNA and integrated transcripts of HPV18 in the chromosomes of EC109 cells. The final nested PCR products were cloned into a pMD-18T vector and sequenced to analyze the chromosomal location of HPV integration. HPV18 DNA was detected in EC109 cells by PCR using the general primer sets of My09/11 and GP5 +/6 + for HPV L1 and the type-specific primer sets for HPV18 E6 and E6-E7 to generate products of 450 bp, 150 bp, 335 bp and 944 bp, respectively. Approximately 600 bp of integrated HPV18-specific transcript was identified. The final nested PCR product of integrated HPV18 DNA was cloned into a pMD-18T vector and sequenced to analyze the chromosomal location of HPV integration. Sequence alignment showed that the HPV18 sequence from EC109 cells was identical to that of the encoded early protein E7-E1 of the standard HPV18 strain X05015, and another partial gene sequence was identical to a partial sequence of human chromosome 8. Integration of the HPV genome into the host cell chromosome suggests that persistent HPV infection is vital for malignant cell transformation and carcinogenesis.
Article: Analysis of related factors of premature delivery for the migrant population in local suburban Beijing areas[Show abstract] [Hide abstract]
ABSTRACT: To study the health conditions of pregnant migrant women in some suburban areas of Beijing by comparing a variety of pathological, physiological and social factors and exploring the relevant factors associated with preterm birth so as to prevent effectively preterm birth. A total of 279 cases of pregnancy in preterm birth at out hospital from January 2004 to December 2008 were reviewed. The date of maternal age, parity, prenatal examinations, history of vaginitis, history of chorioamnionitis, premature rupture of membranes, occupation, residing location and education status were recorded. And the relationship between them and preterm birth were analyzed by χ(2) test. The overall incidence of preterm birth was 5.34%. And the following factors had statistically significant differences with premature birth: chorioamnionitis, vaginitis, premature rupture of membranes, a lack of prenatal examinations, low education status, migrant population or maternal parity. However there was no statistical significance (P > 0.05) between preterm birth and other factors, such as occupation. The incidence of preterm birth is associated with a lack of prenatal examinations, low education status, chorioamnionitis, bacterial vaginitis and premature rupture of membranes. Therefore the migrant women in Beijing should receive targeted education programs during pregnancy. And reproductive tract inflammation should be properly treated.
Article: Specific cellular immune responses in mice immunized with DNA, adeno-associated virus and adenoviral vaccines of Epstein-Barr virus-LMP2 alone or in combination[Show abstract] [Hide abstract]
ABSTRACT: Cellular immune responses, particularly those associated with CD3(+)CD8(+) cytotoxic T lymphocytes (CTL), are critical factors in controlling viral infection. Nasopharyngeal carcinoma (NPC) is closely associated with persistent Epstein-Barr virus (EBV) infection. NPC vaccine studies have focused on enhancing specific antiviral CTL responses. In this study, three vaccines capable of expressing the EBV-latent membrane protein 2 (LMP2) (a DNA vector, an adeno-associated virus (AAV) vector, and a replication-defective adenovirus serotype 5 (Ad5) vector) were respectively used to immunize female Balb/c mice (4-6 weeks old) at weeks 0, 2 and 4, either alone or in combination. Our results suggest that combined immunization with DNA, AAV, and adenovirus vector vaccines induced specific cellular immunity more effectively than any of these vectors alone or a combination of two of the three, constituting a sound vaccine strategy for the prevention and treatment of NPC.
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ABSTRACT: To obtain a second Epstein-Barr virus membrane protein (LMP2) in insect cells. The full length EBV-LMP2 gene was inserted into baculovirus expression transfer vector pFastBac HT B to obtain the recombinant baculoviruses Bac-LMP2. And generation of recombinant baculoviruses was followed by transfection of the recombinant Bac-LMP2 into insect cells, then the recombinant LMP2 protein was recognized by SDS-PAGE and western blot. The expressed LMP2 protein was purified by one step with Ni-NTA metal chelation chromatography. The expressed LMP2 protein was confirmed by SDS-PAGE and western blot. The purity of purified LMP2 protein is up to 86% by HPLC analysis. The EBV-LMP2 was expressed in insect cells, and the purified LMP2 protein was obtained.
Article: Li S, Du H, Wang Z, Zhou L, Zhao X, Zeng YMeta-analysis of the relationship between Epstein-Barr virus infection and clinicopathological features of patients with gastric carcinoma. Sci China Life Sci 53: 524-530[Show abstract] [Hide abstract]
ABSTRACT: Epstein-Barr virus (EBV) infection has been causally associated with occurrence of many malignant neoplasms. EBV-encoded small RNAs (EBERs) have been detected from about 10% of gastric carcinoma tissue cells, suggesting that EBV infection is associated with the development of gastric carcinoma. The present study pooled the data from the papers concerning EBV-related gastric cancers and performed a meta-analysis of 22 research papers. Among these papers, a total of 5475 cases with gastric cancer were enrolled, of whom 411 cases were found EBV-positive, with the EBV-positive rate being 7.5%. Among the EBV-positive gastric cancer cases, the detection rate was 11.1% in males and 3.0% in females. Compared with EBV-negative gastric cancer, EBV-positive gastric cancer had less lymph node metastasis. Based on the histological typing, of the EBV-positive gastric cancers, the diffuse type was 8.1%, and intestinal type was 8.0%. The examined specimen types included stored paraffin blocks and fresh surgically removed specimens, their EBV positive rates were 7.9% and 6.5% respectively. In terms of geographical distribution, the detection rate of EBV-positive gastric cancer was 9.4% in America, 6.1% in Asia and 9.1% in Europe. Meta-analysis showed that EBV infection occurred only in gastric cancer tissue cells and was significantly associated with the patients' gender, lymph node metastases, and the location where tumor tissue generated and geographical distribution (P<0.05), but was not significantly associated with the patients' histological types of tumor and the types of specimens (P>0.05). These results suggested that EBV-positive gastric cancer has distinct clinicopathological features.
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ABSTRACT: To investigate the effects of various factors upon subclinical chorioamnionitis (SCCAS) during pregnancy and delivery. A total of 796 cases of pregnancy in full-term birth at our hospital from December 2006 to December 2008 were reviewed. The data of maternal age, gravidity, parity, gestational age, prenatal care, history of vaginitis, premature rupture of membranes, occupation, educational status and delivery mode were recorded. And then the relationship between one of them and chorioamniotis were analyzed by chi(2) test. The overall incidence of SCCAS was 39.95% in full-term birth. The pregnant women, who had no prenatal care or no occupation, or had a history of vaginitis or premature rupture of membranes, were found to have a higher incidence (P < 0.05 or P < 0.01). However, there were no statistical significance (P > 0.05) between SCCAS and other seven factors, such as gravida age, gravidity, parity, gestational age, educational status, delivery mode and living conditions. Women with full-term birth, even in the absence of symptoms, may have already suffered from acute or chronic chorioamnionitis. The incidence is associated with prenatal care, history of vaginitis and premature rupture of membranes.
Article: [Expression and purification of avian influenza virus H5N1 NP protein, and screening interaction proteins of host cells in vitro].[Show abstract] [Hide abstract]
ABSTRACT: To express and purify H5N1 influenza virus (A/Anhui/1/2005) NP in prokaryotic system and to explore the NP-interacting proteins of human bronchial epithelial cells BEAS-2B in vitro. The full length H5N1 NP gene fragment was amplified by PCR, inserted into prokaryotic expression vector (pET30a) to generate NP expression plasmid pET30a-NP. After transforming pET30a-NP into E. coli (BL21), the expression of soluble NP protein was induced by IPTG. The expressed NP protein was purified by two steps with metal chelation chromatography and ion exchange chromatography. Then the total proteins of BEAS-2B cells was extracted for screening the components which have protein-protein interaction with purified NP by pull-down and LC-MS/MS methods. The expression of H5N1 NP protein could be induced by IPTG in bacterial system using expression plasmid pET30a-NP. The soluble NP was purified. Twenty proteins were found by pull-down and LC-MS/MS, the further experiments may be needed to prove protein-protein interaction between them. The soluble H5N1 NP fusion protein with high purity was obtained and twenty proteins were found which could interact with it by pull-down and LC-MS/MS.
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ABSTRACT: To investigate the expression feature of peroxiredoxin III in cervical lesions and to further understand the mechanism for cervical cancer development/progression. Expression of peroxiredoxin III was immunohistochemically detected in cervical cancer. In addition, cervical epithelia were transfected with recombinant adeno-associated virus vector containing human papillomavirus 16 E6/E7 and peroxiredoxin III expression was detected by quantitative real time PCR and Western blotting. Peroxiredoxin III was significantly up-regulated in cervical cancer tissues. Nevertheless, expression of peroxiredoxin III remained unchanged in cervical epithelial cells after transfection. It seems that Prx III is not related to cervical cancer initiation. Up-regulation of peroxiredoxin III in cervical cancer might be an active response to oxidative stress in malignant cells, which protects against oxidatiton-induced apoptosis.
Article: Analysis of Epstein-Barr viral DNA load, EBV-LMP2 specific cytotoxic T-lymphocytes and levels of CD4+CD25+ T cells in patients with nasopharyngeal carcinomas positive for IgA antibody to EBV viral capsid antigen[Show abstract] [Hide abstract]
ABSTRACT: Epstein-Barr virus (EBV) is a herpesvirus commonly associated with several malignant diseases including nasopharyngeal carcinoma (NPC), which is a common cancer in Southeastern Asia. Previous studies showed that plasma levels of EBV-DNA might be a sensitive and reliable biomarker for the diagnosis, staging and evaluating of therapy for NPC. There are a few analyses of the levels of EBV-latent membrane protein 2 (LMP2)-specific cytotoxic T-lymphocytes (CTLs) in patients with NPC. This study was conducted to investigate the levels of EBV-LMP2-specific CTLs, EBV-DNA load and the level of CD4(+)CD25(+) T cells in such patients. From February 2006 to April 2006, 62 patients with NPC, 40 healthy virus carriers positive for EBV viral capsid antigen (EBV-IgA-VCA) and 40 controls were enrolled in the study. We used a highly sensitive ELISPOT assay, real-time polymerase chain reaction (PCR) and flow cytometry to measure the EBV-LMP2-specific CTL response, the EBV DNA load and the level of CD4(+)CD25(+) T cells, respectively. The EBV-LMP2-specific CTL responses of the samples from the control, healthy virus carriers and patients with NPC were significantly different from the LMP2 epitopes, with the control and healthy virus carrier samples displaying a stronger response in three cases. There were significant differences in EBV DNA load in serum between NPC and the healthy groups; patients with NPC at stages III or IV had significantly higher viral loads compared with those at stages I or II. A significantly higher percentage of CD4(+)CD25(+) T lymphocytes were detected in the patients, compared with healthy virus carriers and healthy controls. Moreover, patients with advanced stages of NPC (III and IV) had significantly higher percentages than the patients with early stages (I and II). Patients with NPC are frequently unable to establish or maintain sufficient immunosurveillance to control proliferating B cells harboring EBV and to destroy the tumor cells that express immunodominant LMP2 proteins. Controlling the activity of CD4(+)CD25(+) T cells and elevating CD8(+) cells specific for LMP2 epitopes could be an effective immunotherapy for patients with NPC.
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ABSTRACT: To develop the rationales for ovarian cancer-specific protein profiles in serum and to analyze the protein profiles of multidrug resistance P-glucoprotein (MDR1) and multidrug resistance-associated protein (MRP) positive and negative expression sets for a rapid and sensitive serum protein pattern. Serum protein profiles from 36 epithelial ovarian cancer cases were compared with 30 healthy controls using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (DELDI-TOF-MS). Blinded test was conducted subsequently for identification of the protein pattern. Expression of MDR and MRP were detected in set of training cases by immunohistochemistry. The spectra were analyzed statistically between positive and negative groups. Twenty-nine peaks were significantly different between ovarian cancer and healthy controls (P < 0.01, 15 peaks up-regulated and 14 down-regulated). A set of three peaks, at 5 486, 6 463 and 8 575 m/z respectively, were selected from 29 sense peaks as an ovarian cancer biomarker. The sensitivity was 100% and specificity 93.33%. Identification by blinded validation indicated a positive predictive value of 90%. MDR1 expression in ovarian cancer was 69.4 %. Twenty peaks were significantly different between positive and negative sets (P < 0.01). MRP expression in ovarian cancer was 63.8%. But one peak was detected (P < 0.01). It was an ideal pattern for employing the SELDI mass spectrum approach to diagnose ovarian cancer and select the multidrug resistance cases. Serum biomarkers for detecting drug resistance in ovarian cancer can be established on the basis of MDR1 immunohistochemistry.
Article: [Genetic analysis of the complete env genes of HIV-1 from paid blood donors in Henan province].[Show abstract] [Hide abstract]
ABSTRACT: Complete HIV-1 env genes were amplified by nested PCR from uncultured peripheral blood mononuclear cells (PBMCs) DNA of 60 HIV-1 positive paid blood donors in Henan province, and the amplified full-length genes were sequenced. Twenty one full-length env genes were obtained, sequence analysis found that 15 of them had intact open reading frame (ORF). Fourteen sequences conformed to subtype B', their average genetic distance with the international reference sequence RL42 was 4.87% +/- 0.31%. One was subtype B, its genetic distance with the international reference sequence HXB2 was 5.43%. The amino acid sequences of these env genes were deduced according to their nucleotide sequences and extensive analysis and comparison of important structural motifs were performed. The results indicated that there was no drastic alteration in the number and position of potential N-linked glycosylation sites among these 15 sequences. And the residues involved in forming the CD4 binding site were highly conserved. Genotype prediction of coreceptor usage based on V3 sequence and net charge suggested that most samples use CCR5 coreceptor. GPGR motif at the tetrapeptide crown in the V3 loop was most common in these samples and it was detected in 40% sequences. The cleavage site of gp120/gp41 was highly conserved, so Gp160 precursor of all isolates would be efficiently cleaved into the Gp120 and Gp41 subunits. The known neutralizing antibody binding sites for 2G12, IgG1b12, 4E10 and 2F5 were also highly conserved, it is expected that most of these isolates will be sensitive to neutralization by these antibodies. Further study to elucidate the correlation of the env genotype to functionally relevant motifs is necessary and that will aid vaccine and novel drug design.
Article: [Meta analysis on etiological relationship between human papillomavirus and esophageal carcinoma].[Show abstract] [Hide abstract]
ABSTRACT: To study the relationship between human papillomavirus (HPV) and esophageal cancer development in China. We searched and collected the published articles in Chinese related to HPV and esophageal cancer, and selected the articles with the PCR approach to detect HPV in the esophageal cancer specimens. We filtered our publication collection with standards as (1) PCR as the detection approach, (2) specimens as the paraffin-embedded sections, and (3) description of the primer in the experiments, and fifteen articles were enrolled for our meta-analysis. Among the articles, totally 980 specimens were tested, and 460 were HPV positive with the average HPV prevalence was 46.9% (95% CI: 43.8%-50.0%), varied from 8.3%-69.8% in the different locations. On the other hands, among 556 specimens whose HPV detection spectrum included HPV16, 139 showed the positivity of HPV16, the average prevalence was 25.0%, (95% CI: 21.4%-28.6%) varied from 4.4%-63.4% dependent on the locations; among 485 specimens whose HPV detection spectrum included HPV18, thirty-three specimens showed the positivity of HPV18, the average prevalence was 6.8% (95% CI: 4.6%-9.0%) varied from 0%-19.0% dependent on the locations. Third, among the fifteen articles enrolled in the meta-analysis, four articles used the same primer set for HPV detection in totally 406 paraffin-embedded specimens with the prevalence of 40.2% (95% CI: 36.0%-45.4%) varied from 20.3%-67.6% in different locations. Our analysis result suggested the HPV prevalence in the esophageal cancer samples of China and clued the possible etiological relationships between HPV infection and the esophageal cancer development.
Article: [Detection of human papillomavirus in esophageal carcinoma tissues from Baoding City of Hebei Province].[Show abstract] [Hide abstract]
ABSTRACT: To investigate the relationship between the human papillomavirus (HPV) and esophageal carcinoma in Baoding City of Hebei Province. We detected HPV DNA in 42 formalin-fixed and paraffin-embedded tissues from surgically resected esophageal carcinomas from Baoding City of Hebei Province, by PCR with the general primer set of GP5 + /6 + for HPV L1 gene and type-specific primer sets for HPV16 and 18 as well. 37 from 42 esophageal carcinoma samples were HPV positive and the rate was 88.1%. Among the samples detected, 19 were HPV16 E6 positive and rate was 45.2%, eight were HPV18 E6 positive and rate was 19.0%. The high rate of HPV in the esophageal carcinoma samples suggested that HPV plays an etiologic role in the development of esophageal cancer in Baoding City of Hebei Province.
Article: [An improved BALB/c 3T3 cell transformation assay and its application in the cocarcinogenesis study].[Show abstract] [Hide abstract]
ABSTRACT: To improve the protocol of BALB/c 3T3 cell transformation assay, and apply it to the cocarcinogenesis study. Appropriate serum concentration, culture media and method of administration were selected by testing their effects on the growth and transformation of BALB/c 3T3 cells. The co-carcinogenic activity between diethylnitrosamine (DEN) and microcystin-LR (MC-LR) or 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) were examined using the improved cell transformation assay. The malignant characteristics of transformed cells were verified by neoplasia in SCID mice. There were strong co-carcinogenic activity between DEN and TCDD. On the contrary, although MC-LR has strong ability to induce cell transformation, the effect was markely inhibited by DEN. The transformed cells show some malignant characteristics. The improved BALB/c 3T3 cell transformation assay is reliable and time-saving, and can be efficiently used in the study of cocarcinogenesis.
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ABSTRACT: To investigate the application of 293 cells to detect suspected carcinogens and provide experimental evidence by using in vitro cell transformation assay and tumorigenicity study. The transformation systems of cells cultured in vitro have been adopted to clarify the tumor promotive activity of Microcystin LR (MC-LR). The malignant transformation of 293 cells induced by MC-LR is tested by several methods including clone forming in soft agarose, serum requirement assay and tumor forming in mice to define the promotive activity of 293 cells. 293 cell acted like tumor cells after induced by MC-LR: serum dependence decreased, anchorage independence growth in soft agarose and formed cell clones, malignant tumors appeared in SCID mice. 293 cells were easy to culture and sensitive to environmental carcinogens so that can be used in detection of suspicious carcinogens.
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ABSTRACT: To improve the existing serological early diagnosis method of nasopharyngeal carcinoma by improve the detection sensitivity. The samples of 294 serum specimen from the prevention and treatment of nasopharyngeal cancer model base, involving 106 serum specimen from the patients suffering from nasopharyngeal cancer and 188 from the healthy testers. IgA/VCA antibody and IgA/EA antibody of the serums are tested by Streptavidin-biotin-antibody immunoenzymatic test and normal traditional enzyme methods, SPSS statistical software is used to analyse the test results with chi2 test and t test. Referring to 106 patients, the sera antibody positive rate tested by Streptavidin-biotin-antibody immunoenzymatic test method is obviously higher than that tested by traditional method; and the t test result of the GMT has significant difference in the two method. The modified method can improve the sensitivity of serology testing, ensure the specificity of test results, at the same time, improve the detection rate of nasopharyngeal carcinoma, so it can be applied to the early screen work of nasopharyngeal carcinoma.
Top Journals
Chinese Center For Disease Control And Prevention
Peping, Beijing, China
- Institute for Viral Disease Control and Prevention
Beijing Centers for Disease Control and PreventionPeping, Beijing, China
Beijing University of TechnologyPeping, Beijing, China
Guangxi Medical University
Yung-ning, Guangxi Zhuangzu Zizhiqu, China
- First Affiliated Hospital


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Respond to Review of Heart of Joy
by Vesna
Review: Having breakfast at the restaurant Heart of Joy was really a positive experience, a joy for the heart :). It's cheap and food is good, very good. Clean with a really friendly staff. definitely to repeat when we come back to this wonderful city!
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Top Definition
he had smizz on his face
بواسطة yellow t shirt سبتمبر 20, 2010
Smizz: To smoke weed !
Hey man lets smizz this J and go to a bar.
بواسطة Anonymous يوليو 27, 2003
a stupid or dumb slut a synonym to smut used in new jersey in the bergen county area mainly elmwood park and lodi
Look at that chikk. you can tell shes a smizz by the way she walks.
بواسطة dpimpssz سبتمبر 24, 2007
1) A cigarette or "smoke".
2) To engage in smoking.
1) A cigarette or "smoke".
2) To engage in smoking.
n. 1. Hey, can I bum a smizz?
v. 2. I'm going to go smizz before I go to work.
v. 2. I'm going to go smizz before I go to work.
بواسطة Morbid ديسمبر 28, 2002
N. A creature (human or non-human) who is extremely sexually active with more than one person(s).
I saw her with Darren last week and today she's with Jimmy! This girl is a smizz cuhhhhh!
بواسطة melanie greenfielde ديسمبر 31, 2008
i made this up as a code word between me and my friends in 1999. i have no clue how it got so big. -linc
Wanna go smizz a J?
Nah I just smizzed.
Nah I just smizzed.
بواسطة the missing linc ديسمبر 20, 2004


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CA District 19: D19 District Training
D19 District Training
Below we will list all District 19 Training that will be provided throughout the season. For District training it is MANDATORY that a Board Representative from each league be present. Your dedication and support is appreciated!
2015 District Training events:
Baseball Fundamentals Field Clinic UPDATED VENUE :
Little League Field Clinic & Training for players ages 9-15
Hosted by: Azusa Pacific University Head Coach Paul Svagdis and the APU Cougar Baseball Staff
Saturday February 21, 2015 1:00pm at Azusa Pacific University Cougar Baseball Stadium
This year Coach Paul Svagdis along with his NCAA Cougar baseball team will be performing the field clinic bringing philosophies and fundamentals to the baseball field with hands on demonstrations and player participation covering infield, outfield, hitting, base running, hitting, pitching and catching. This is sure to be a training seminar you do not want to miss.
More details will follow soon on this field clinic for CA District 19 players ages 9-15.
Please read the Bio on Head Coach Paul Svagdis by clicking on the link below:
Youth Baseball Fundamentals By: Paul Svagdis
2014 District Training events:
Manager & Coaches Training:
Little League Coaches Field Clinic & Training
Hosted by: Azusa Pacific University Head Coach Paul Svagdis and the APU Cougar Baseball Staff
Thursday January 23, 2014 6:30pm at Azusa Pacific University Cougar Baseball Stadium
Enclosed in this manual each coach will find a detailed practice plan, overall philosophies on hitting, fielding, and base running, descriptions of every drill, as well as the overall purpose of each drill. Coach Svagdis will also teach the role of the coach in facilitating the learning process by understanding the basic fundamentals and staying focused on teaching those fundamentals through the drills and practice plans. Staying focused on the basic fundamentals and purposes of each drill will help the athletes begin to master each skill set.
You do NOT want to miss this interactive training seminar and hands on field clinic. One night only on campus at Azusa Pacific University in the Cougar Baseball Stadium. This seminar and clinic is leading right up to the start of the 2013 regular season of CA District 19 Little League baseball and softball.
Please begin contacting your Baseball and Softball coaches to inform them of this awesome opportunity to learn from one of the nations premier coaches.
Please read the Bio on Head Coach Paul Svagdis by clicking on the link below:
Fundraising Coordinators:
Date: TBA
Time: TBA
Place: TBA
Player Agents:
Date: TBA
Time: TBA
Place: TBA
Monday, June 8
2015 Major TOC baseball
Monday, June 8
2015 Minor TOC baseball
Wednesday, June 3
2015 Major TOC softball
Monday, June 8
2015 Senior TOC softball
Monday, June 8
2015 Junior TOC baseball
Friday, June 12
2015 7&8 Select Tournament Softball
Thursday, June 18
2015 7&8 Yr Old Select Baseball
Wednesday, June 24
2015 9-10 Softball All Stars
Thursday, June 4
2015 Minor TOC softball
Saturday, June 27
2015 Junior Baseball All Stars


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Jammu and Kashmir poll observer dies in Tripura
Posted on Mar 19 2014 | IANS
Agartala, March 19 : Pratapaditya Datta, an IAS officer of the 2010 Tripura-Manipur cadre and an election observer for Jammu and Kashmir, died here Wednesday following cardiac arrest, an official said.
He was 50 and is survived by his wife and a child.
"Datta, registrar of co-operatives under the Tripura government, felt uneasy and complained of giddiness while working in office. He was immediately shifted to Agartala Government Medical College and Govind Ballabh Pant Hospital, where he breathed his last," a Tripura government official told reporters.
He twice visited the Udhampur Lok Sabha seat in Jammu and Kashmir as a poll observer.


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I'm building a framework and want developers who build with it to have the ability to allow parts of it to both share data with other sites and allow other sites to add/edit/delete data.
For example, if someone makes a site that has book reviews, authors, quotes, code examples, comments, etc. the developer could make e.g. "book reviews" read-only for other sites and "comments" readable by other sites and writable by certain sites/users. The idea is to use the framework to build applications that can easily be interconnected with other applications.
I envision enabling all interaction with the site via POST and GET which would look something like this:
- /books.php?category=ruby (returns an XML collection of books about ruby)
- /books.php?id=23 (returns the XML for a specific book)
- /books.php?action=add&title=AdvancedRuby&description=....&securityId=923847203487
- /books.php?action=delete&id=342&securityId=923847203487
Other applications could also "discover and consume" what a certain site has to offer by doing this:
- /discover.php (returns XML of all public classes and actions available)
Really this is all I need to enable the framework to be a way for developers to quickly create loosely connected sites.
What I want to know is, before I begin implementing this, are there significant/interesting parts of REST that I do not yet understand which I should be building into the framework, e.g.:
- REST requires GET, POST, PUT and DELETE. Why would I ever need "PUT" and "DELETE"? Am I locking myself out from taking advantage of some standard if I dont' use these?
- My "discover.php" file functions similarly to a WSDL file in web services. I am surprised in descriptions of REST there seems to be no standardized way of discovering the services that a RESTful service offers, or is there?
- If a client website tries to e.g. add a book to a server website and does not get any "success" response back, it would simply try again until it got a response. The server website would simply not add the same book twice. This is my understanding of data integrity in REST, is there more to it than this?
eventually I want to have multiple sites that have the same rich classes e.g. "BookReview" so that a client site would be able to execute code such as this:
$bookReview = new BookReview("http://www.example.com/books.php?id=23"); $book->informAuthor("a comment about your book review was posted on our site...");
and the server site would send an e-mail off to the author of that review. Is this type of type interaction a component of the RESTful philosophy or is REST simply the exchange of data via XML, JSON?


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|This document may not represent best practices for current development, links to downloads and other resources may no longer be valid. Current recommended version can be found here. ArchiveDisclaimer
/HELP (Compiler Command-Line Help)
Visual Studio .NET 2003
/HELP /help /?
This option displays a listing of compiler options to standard output.
To set this compiler option in the Visual Studio development environment
This compiler option should only be accessed from the command line.
To set this compiler option programmatically
This compiler option cannot be changed programmatically.
See Also


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Book your room at Inter-Hotel Seaside Park
Standard StudioMax Occupancy: 2 guests (up to 1 infant)
Comfort StudioMax Occupancy: 2 guests (up to 1 infant)
Standard Apartment, 1 Bedroom (4 pers)Max Occupancy: 4 guests (up to 3 infants)
Standard Apartment, 1 Bedroom (6 pers)Max Occupancy: 6 guests (up to 5 infants)
Get an overview of this hotel3-star suburban hotel near Marineland Antibes
Situated in the business district, this hotel is within 1 mi (2 km) of Marina Baie Des Anges and Marineland Antibes. Antibes Land and Joa Casino La Siesta are also within 1 mi (2 km).
Hotel Features
This hotel features a fitness center, self parking, and a seasonal outdoor pool. WiFi in public areas is free. Additionally, concierge services, laundry facilities, and express check-in are onsite.
Room Amenities
All 72 rooms feature kitchenettes with refrigerators and dishwashers, plus free WiFi and LCD TVs with digital channels. Sofa beds, sitting areas, and safes are among the other amenities available to guests. Weekly housekeeping is available.Information missing or incorrect? Tell us!Opens in a new window
Hotel Amenities
Hotel Amenities
Inter-Hotel Seaside Park features a fitness center and a seasonal outdoor pool. High-speed wireless Internet access is complimentary. This Villeneuve-Loubet hotel also offers tour/ticket assistance, multilingual staff, and concierge services. Onsite parking is available (surcharge).
- Billiards or pool table
- Breakfast available (surcharge)
- Free newspapers in lobby
- Concierge services
- Elevator/lift
- Express check-in
- Fitness facilities
- Free WiFi
- Front desk (limited hours)
- Laundry facilities
- Multilingual staff
- Number of buildings/towers - 1
- Number of floors - 4
- Outdoor seasonal pool
- Pool sun loungers
- RV, bus, truck parking
- Safe-deposit box at front desk
- Self parking (surcharge)
- Total number of rooms - 72
- Tours/ticket assistance
Business Travel Amenities
- Dry cleaning or laundry services
- Concierge services
- Express check-in
- Free WiFi
- Multilingual staff
Family Friendly Amenities
- Free Wi-Fi
- Kitchenette
- Laundry facilities
- Microwave (on request)
- Refrigerator
- Sofa bed
Available in all rooms: Free WiFi
Available in some public areas: Free WiFi
Self parking (surcharge), RV, bus, truck parking
Room Amenities
- Air conditioning
- Blackout drapes/curtains
- Cribs/infant beds (surcharge)
- Digital TV service
- Dishwasher
- Free WiFi
- Hair dryer (on request)
- In-room safe
- Iron/ironing board (on request)
- Kitchenette
- Microwave (on request)
- Private bathroom
- Refrigerator
- Separate sitting area
- Shower only
- Sofa bed
- Sofa bed size
- Weekly housekeeping provided
Where to Eat
Buffet breakfasts are available for a surcharge and are served each morning between 7 AM and 10 AM.
Nearby Things to Do
Recreational amenities at the hotel include a fitness center and a seasonal outdoor pool.
Children under 12 years old are not allowed in the swimming pool or fitness facility without adult supervision.
The recreational activities listed below are available either on site or nearby; fees may apply.
- Golfing nearby
- Snorkeling nearby
- Surfing/boogie boarding nearby
- Sailing nearby
- Scuba diving nearby
- Water skiing nearby
- Windsurfing nearby
- Bicycle rentals nearby
- Scooter/moped rentals nearby
- Parasailing nearby
- Golf lessons available nearby
To make requests for specific accessibility needs, complete the "Special or Accessibility Requests" section of "Trip Preferences" when you book your hotel.
Hotel Policies
Check-in time ends at 9 PM
Check-in time starts at 3 PM
Minimum check-in age is 18
Special check-in instructions:
Check-out time is 11 AM
Payment types
Children and extra beds
- Children are welcome.
- Cribs (infant beds) are available for EUR 2.5 per night.
Pets allowed, Only dogs and cats are allowed, Maximum number of pets per room 1, Pet maximum weight in kg is 15
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
No rollaway/extra beds available
- Deposit: EUR 250 per stay
- A tax is imposed by the city: EUR 1.10 per person, per night
Optional extras
- Fee for buffet breakfast: EUR 9,50 for adults and EUR 5 for children (approximately)
- Self parking fee: EUR 6 per day
- Pet fee: EUR 10 per pet (varies based on length of stay)
- Late check-out fee: EUR 50
- Kitchen/kitchenette fee: EUR 9 per day
- In-room safe fee: EUR 3.5 per night
- Crib (infant bed) fee: EUR 2.5 per night
Hotel Name
- Seaside Park Hotel Villeneuve-Loubet
- Seaside Park Villeneuve-Loubet
- Inter-Hotel Seaside Park Hotel Villeneuve-Loubet
- Inter-Hotel Seaside Park Hotel
- Inter-Hotel Seaside Park Villeneuve-Loubet
- Inter-Hotel Seaside Park
We should mention
Only registered guests are allowed in the guestrooms. Guests can arrange to bring pets by contacting the property directly, using the contact information on the booking confirmation (surcharges apply and can be found in the Fees section).


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Woody Harrelson and Antonio Banderas star as best friends and professional boxing rivals Vince Boudreau and Caesar Dominguez, both of whom haven't worked in years. Finally, from out of the blue, they get the chance of a lifetime: an assignment to work together in Vegas. The job promises big money, but there's a hitch: They have to be there now.
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This question already has an answer here:
A have a large div (a map) that is draggable via jQuery UI draggable. The div has child divs which are clickable.
My problem is that if you drag the map, on mouse up, the click event is fired on whatever child div you started the drag from.
How do I stop the mouse up from triggering the click event if its part of a drag (as opposed to someone just clicking without a drag, in which case the click event is desired).


text:
Posted by gman on 5/17/2012, 3:24 am, in reply to "Re: Rob"
Now that you applied hydrocide hope she don't
call you and say "My dog is sick"! she might
be that type of person. Only you know.
The best thing she could of done was replaced
it with new carpet. That dog stench is in the
fibers, backing, pad, walls, upholstery, and
as Jim said her head..
Message Thread
« Back to index
The JAGUAR 8.4 INDUSTRIAL SYSTEM; not your generic squirt & suck machine!


text:
- 26Promote
Canvas Print
redby Mary Carroll
Fine art print on bright white, fine poly-cotton blend, matte canvas using latest generation Epson archival inks. Individually trimmed and hand stretched museum wrap over 1-1/2" deep wood stretcher bars. Includes wall hanging hardware.
Thanks so much, Beverly! :)
Awesome shot!
Thanks so much, Kurt!
Thank you so much, Carol!
love your work!
Thank you for your kind words, Elle!
lovely light
Thank you, catspaws!
Thanks so much, Garima!
Thank you, Carol!
beatiful :)
Many thanks, Carina!
Beautiful light!
beautiful lighting and composition :)
Thanks so much, Christine!
Thank you, Nicola!
Thank you so much, Lessa!
Thank you so much, Armine!
Oh Yeah! ✯ ✯ ✯ ✯ ✯ 👍
Thanks so much, Wayne!
I love the mood here. ahhhh... :)
Thank you so much, Katya!
See More Comments


text:
'Being Bettie' in Et Alors? magazine by twiggetteWatch
©2011-2016 twiggette
In stores now...
I am most envious of Her predicament... To be over Her knee, looking like that, about to be spanked. That lovely feeling of anticipation and excitement.... that disappears the first instant the paddle strikes and the pain starts. Owww! Ahhh... good memories.
nope,the heels gave it away
spank spank! you've been a bad girl! after the spanking you wil also get a painful injection!
Absolutely love this one.
Asian Domme. Yum!
Betty My late Husbands favorite
Betty My late Husbands favorite
classical betti.. nice
Poor Betty! That paddle sure ought to leave some welts!
Whatv an authentic re-creation,right down to her heels!
Board games are lots of fun when played as an adult. Great shot of a reminder of a timeless beauty...a real, live woman.
Sooooo beautiful!
You have to appreciate the trouble the photographer went through to re-create the feel of the old Bettie Page spanking pictures, even putting Bettie's bangs on a model. This is better-posed than Bettie's old pictures though, as far as the over the knee positioning is concerned. Nice paddle, although it's too long to be used effectively OTK - "Bettie" should have been bending over to receive her swats with it.
Thanks. I tried to copy the feeling of her photos without actually copying them. Glad it worked out well
Excellent, reminds me of Bettie Paige's first shots


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No matter how much an order weighs, we will ship any order of Suzuki Samurai Fuel Pump parts to the 48 states at no cost to you. Find out why other Suzuki Samurai Fuel Pump parts customers order from us by ordering your Suzuki Samurai Fuel Pump parts on our web store. If you ever have a problem with your order, we will do our best to correct the problem. Hundreds of thousands of other customers use us, try us and find out why. You never need to clip coupons. Call our hotline and let us transfer you to our Suzuki Samurai Fuel Pump parts specialist. OE Suzuki Samurai Fuel Pump parts means we sell original equipment auto parts. We service hundreds of thousands of customers online.
Allen S. - Lakewood, CO: Tom, Thank you so much for catching my order error on the SAAB hood struts. You gave exceptional service. Thanks for getting everthing shipped correctly. I am SOLD on autohausaz.com for all my parts.
Eric M. - Cumming, GA: Thanks so much Tom! I appreciate your time and help. I definitely found a new place to get my VW parts. I drive a '85 GTI and my wife a '96 Jetta. Thanks again.


text:
Bill Text — Sep 22, 2011
H.R. 3011 (112th): Transportation Security Administration Authorization Act of 2011
This bill's text is now available.
GovTrack Insider, our Kickstarter-backed work to summarize bills in Congress, has resumed. Here's what we've been up to:
Apr 14, 2011
112th Congress, 2011–2013
This bill was introduced on April 14, 2011, in a previous session of Congress, but was not enacted.
Representative for New York's 18th congressional district
Read Text »
Last Updated: Apr 14, 2011
Length: 9 pages
To amend title 49, United States Code, to prohibit advance notice to certain individuals, including security screeners, of covert testing of security screening procedures for the purpose of enhancing transportation security at airports, and for other purposes.
The bill's title was written by its sponsor.
Earlier Version — Passed House
This activity took place on a related bill, H.R. 5909 (110th).
Earlier Version — Introduced
This activity took place on a related bill, H.R. 2464 (111th).
This is the first step in the legislative process.
This is a House of Representatives bill in the United States Congress (indicated by the "H.R." in "H.R. 1554"). A bill must be passed by both the House and Senate in identical form and then be signed by the President to become law.
The committee chair determines whether a bill will move past the committee stage.
There have been no roll call votes related to this bill.
Legislative action may be ocurring on one of these bills in lieu of or in parallel to action on this bill.
Referred to Committee
Last Action: May 18, 2009
Referred to Committee
Last Action: Sep 22, 2011
Search for similar bills.
THOMAS.gov (The Library of Congress)
GovTrack gets most information from THOMAS, which is updated generally one day after events occur. Activity since the last update may not be reflected here. Data comes via the congress project.
Click a format for a citation suggestion:
Civic Impulse. (2016). H.R. 1554 — 112th Congress: Catching Operational Vulnerabilities by Ensuring Random Testing Act of 2011. Retrieved from https://www.govtrack.us/congress/bills/112/hr1554
"H.R. 1554 — 112th Congress: Catching Operational Vulnerabilities by Ensuring Random Testing Act of 2011." www.GovTrack.us. 2011. February 11, 2016 <https://www.govtrack.us/congress/bills/112/hr1554>
{{cite web
|title=H.R. 1554 (112th)
|accessdate=February 11, 2016
|author=112th Congress (2011)
|date=April 14, 2011
|quote=Catching Operational Vulnerabilities by Ensuring Random Testing Act of 2011


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STARmeterSEE RANK
Up 1,067,765 this week
Werner Eichhorn (1922–2005)
Werner Eichhorn was born on November 15, 1922 in Leal, Estonia. He was an actor, known for Der Zauberberg (1982), The Lost Honor of Katharina Blum (1975) and Eine ungehorsame Frau (1998). He died on July 14, 2005 in Hamburg, Germany. See full bio »
Born:in Leal, Estonia
Died:(age 82) in Hamburg, Germany


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PORTSMOUTH — A revitalized town panel's ideas for bringing in new business here include attracting a big-name hotel, consideration of an entertainment or sports facility located at the former landfill and creating an entity like Shelburne Farm in Vermont.
The bold ideas came out of the Portsmouth Economic Development Committee's (PDEC) annual report presented to the Town Council Monday night.
Ray Berberick, PDEC chairman, told the council that the committee, which has new membership and leadership since January 2013, is taking a "back to basics" approach that emphasizes "closing the gap" — finding additional revenue for the town.
He also said the committee wants to engage the council and the town in general on the revenue side to lower taxes.
"We ask you to make economic development job one going forward using the bully pulpit," said Mr. Berberick.
Among the new initiatives undertaken by the PDEC is that the Town Council and Town Administrator John Klimm considering forming an Economic Council to exchange key information on economic development across several boards and committees. The Economic Council would education local residents on the provisions of the updated town Comprehensive Community Plan, and also use various media to get the word across "that the town has changed and is now business friendly," the report reads.
Council President James Seveney said he "would like to see some metrics" on how the town is progressing in attracting new business to lower the tax burden on local residents. He said the right mixture of recreational and commercial development seems to be the key to real tax relief.
Mr. Berberick agreed, but said the town has its work cut out for itself. "We'd have to have a whole other Carnegie development to wander into town to get rid of that 2 percent" tax increase, he said. "Moving the needle is going to be quite a challenge."
Wording of agenda item questioned
Council members were preparing to vote on endorsing the PDEC's vision going forward when Town Solicitor Kevin Gavin interrupted them to advise against it. The meeting's agenda, he explained, didn't indicate that the council would take any action on the report.
Mr. Gavin mentioned that Judi Staven was in the audience and that while he didn't want the council "to walk on eggshells," it should err on the side of caution when it came to the Open Meetings Act.
Ms. Staven, a former council member, filed an Open Meetings Act complaint against the current council last fall, alleging that an Oct. 15, 2013 agenda item, "Prudence Island Ferry Update," did not adequately inform the public of the nature of the business to be discussed. In February, the state attorney general's office ruled in Ms. Staven's favor.
(Another resident, John Vitkevich, recently won a similar ruling against the council, regarding an improperly posted agenda item about the former Elmhurst School chapel on Oct. 29, 2013.)
The council then voted unanimously to simply receive the PEDC report and place it on the next council agenda for discussion and vote.
Ms. Staven took exception to the solicitor's mentioning of her name.
"I would certainly hope that just the fact that I was here wasn't the reason he spoke up about the Open Meetings Act," she told the council. "It needs to be on the agenda if you're going to vote on it."


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With several recent fatal incidents involving police, it's important that citizens know their rights when coming face-to-face with an officer.
Between the death of Michael Brown in Ferguson, Missouri and Eric Garner in Staten Island, it's clear that mistreatment, distrust and fear between the police and the people can be a recipe for disaster.
NYPD Detective Chuck Berkley says it's important...
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Indy 11 kick off on the circle
Players for Indianapolis' new professional soccer team, the Indy Eleven, from left, Jon Dawson, Erick Norales and Walter Ramirez were on hand at the team's kickoff party on Tuesday, March 11, 2014 at the Emmis Communications Building on Monument Circle to publicize their inaugural season that begins in just one month, a home game against the Carolina RailHawks on Saturday, April 12.
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- You are here: Home > TRAINING > Undergraduates > CRG Summer Internship Programme
You are here
CRG Summer Internship Programme
CRG Summer Internship Programme
3rd Summer Internship Program for Undergraduate Students
- Description of the Programme
- Eligibility criteria
- Duration
- Application Process
- Stipend
- Reporting
- Participating Research Groups
- Call calendar 2015 selection round
- Related documents and pages
- Contact
Description of the Programme
The Center for Genomic Regulation (CRG) launches the 3rd Summer Internship Program to provide undergraduate students with the opportunity to conduct summer research at the CRG. The goal of the program is to encourage students, from any nationality, in the pursuit of a scientific career and to introduce them to an international laboratory experience.
A maximum of 8 internship positions will be awarded in 2015.
The programme runs from June 1st to October 30, 2015, and is open to undergraduate students of any nationality who are in their final two years of studies in the Life Sciences or related subjects (e.g. Bioinformatics, Biomedicine, Biochemistry, Pharmacology, Chemistry).
The student will be working under the supervision of the group leader or a senior member of the research group.
Eligibility criteria
- Undergraduates with an excellent academic record and a strong interest in biosciences and biomedical research (prior lab experience is highly recommended)
- Two full years (four semesters) of college course work completed by the time the internship commences
- Not have received an undergraduate degree at the time of the internship (Summer 2015)
- High level of English
Positions will be awarded on a competitive basis taking into consideration the student's academic records and the motivation & reference letter(s).
Each student will be matched with a specific laboratory based on the student's interest and background.
The summer training will consist of 320 working hours (40 hours/ week), distributed over the summer period - (8 weeks) from June 1st to October 30, 2015. The internship start date is left to the discretion of the researchers and the students. The intensive nature of the program requires a full-time commitment from the participant. Students are required to participate in all scheduled activities.
Application Process
Applications for the CRG Summer Internship Program are accepted exclusively online through our online application system. Candidates must prepare their online application in English.
The application will include the following information:
- The registration form duly completed
- Your most recent academic transcript, which should include the title of the courses you have completed thus far and the grades you received.
- Description of your interest for life sciences research, what you hope to gain through your participation in the CRG Summer Internship Program, your vision of what the summer internship will benefit you on a personal and academic level, and the reasons behind your choice.
- One reference letter. Once you have completed the name and contact details of the referee(s) on the online application system, the referee(s) will receive an automatic email and will be invited to send the reference letter via email to the following adress : email@example.com
You will be notified by email each time a new reference letter is received for your file.
All the information must be submitted by the application deadline. Applications received after the deadline will not be considered.
Non - residents in the Barcelona area by the time of application.
- 600€/month
- 1 return ticket to the student's place of residence
- Meal vouchers for the 8-week period
Residents in the Barcelona area by the time of application
- 250€/month
- Meal vouchers for the 8-week period
From this stipend, students are responsible for their own housing.
If the student's university does not provide medical insurance, the CRG will provide medical and accident insurance for the trainnig period.
Participation in the Summer Internship Program does not imply any contractual relationship between the beneficiary and the CRG.
If the student, for any reason, voluntarily withdraws or interrupts the program, any unduly received payments must be returned
At the end of the program, the students will prepare a final report in collaboration with his/her CRG supervisor.
Participating Research Groups
For this call, the CRG Research Groups & Core Facilities that have expressed interest in hosting a student are:
|Research Area
|Fyodor Kondrashov
|Evolutionary Genomics
|Jerome Solon
|Biomechanics of Morphogenesis
|Manuel Mendoza
|Coordination of Cytokinesis with Chromosome Segregation
|Mara Dierssen
|Cellular & Systems Neurobiology
|Matthieu Louis
|Sensory Systems & Behaviour
|Miguel Beato
|Chromatin and Gene Expression
|Luis Serrano
|Design of Biological Systems
|Pedro Carvalho
|Organelle biogenesis and homeostasis
|Sebastian Maurer
|Cytoskeleton dependent RNA distribution mechanisms
|Vivek Malhotra
|Intracellular Compartmentation
Call calendar 2015 selection round
|Call opening
|March 10, 2015
|Call deadline
|April 17, 2015
|Pre-selection of candidates
|April 20-27, 2015
|Notification to candidates
|April 28-30 ,2015
|Start date of internships
|June 1, 2015
|End date of internships
|October 30, 2015
Related documents and pages
For any additional information, please contact:
Imma Falero
Academic Officer
Centre de Regulació Genòmica
Dr. Aiguader, 88
PRBB Building
08003 Barcelona


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15161 Washington St Unit D Ste D, Haymarket, VA 20169
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Minnieland Private Day School
5255 Merchants View Sq, Haymarket, VA 20169
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text:
Interesting info on Floyd:
In stage 17, he used 70+ bottles of water (both drinking and dumping over his head).
His radio malfunctioned on the final climb (he thinks due to the water he poured over his head), so he didn't know his gaps going up the Joux Plane.
He had lost a lot of water/weight in stage 16 so to counteract that (and keep him from sweating) they gave him ice cold bottles of water to pour over his head throughout stage 17. (This kept him from sweating as much - which Lim says is better since you can't replace the water in your blood, which is where sweat water comes from, as quickly as you lose it -- so he had more blood to transport oxygen in his legs)
(Landis allowed publication of his power numbers)
When he made his move on the Col des Saisies he averaged 544 watts in the first thirty seconds of his acceleration. This settled down to a 5-minute peak of 451 watts, which then continued for 10 minutes at an average of power of 431 watts. His 30 minute average was 401 watts.
"Floyd averaged 280 watts for the entire ride, but it was 318 for the last two hours. That is while the bike is moving, so you have take into account that he has all those long descents," Lim said. "On the descents he spent 13.2 percent of his time or 43 minutes coasting. If you spend that much coasting but are as good a descender as he is, you are making up time on the descents as well."
"However, if we don't include the coasting time, he averaged 324 watts while pedalling for the stage and 364 watts over the last two hours. That gave him a total of 5,456 Kjoules of work, at an average cadence of 89 rpm. The nature of it is that everything he did today is within the realms of physiological capacity. It was the style with which he did it, the panache and the bravado and the courage [which stood out]."
Despite the outcome of the ride, Lim said that the outputs weren't actually the best he has seen from Landis. Of course, two and a half weeks of racing will tend to have that effect.