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nataleesmommy09's Mom Answers Activity
stressed at 8 weeks no fetal heartbeat
Most recent answer (01/12/2016):
I went to the Dr and the baby had no heart beat and was measuring 8 weeks and I went back a week later and measured the same still no hea...posted by badllamb32
Is it normal for babies (11mos) to be so warm all the time?
posted by nataleesmommy09 07/08/2010
what can I do to get my 10mo old to start eating more table food?
posted by nataleesmommy09 06/16/2010
Are the bumps or indents in my baby's head normal?
Most recent answer (05/20/2010):
If her doctor hasn't seemed concerned, I wouldn't either.posted by blbarton1
Is there an eating "schedule" my 9mos should be on, including her formula?
Most recent answer (05/04/2010):
My daughter is 7 months old and here is what the pediatrician told me at her last visit: -They should be drinking at min. 24 oz. of fo...posted by hatownley
how do i know if my baby is teething, and not ill?
Most recent answer (03/22/2010):
Wash your hands and run your finger tip along her gum line. If her gums are red or swollen most likly she is teething. Her symptoms sou...posted by mayraestrada
why is my baby so irritable?
Most recent answer (03/22/2010):
call the ped and have her ear recheckedposted by ruthless09
How do I get my 1 yr old son to eat something besides his bottle, anything besides his bottle?!?
Most recent answer (02/22/2010):
mine goes through phases that he'll eat something then hate it, feed him the chese or fruit, just keep trying other things, he'll come ar...posted by ruthless09


text: vashiikaran mantra in hindi to control husband+91-9414601882 vashiikaran mantra in hindi to control husband+91-9414601882 babajiksh563 41-45, M 0 May 13, 2014 in Health SEND TO A FRIEND: Your Response Please respond with authenticity, support, and respect Cancel You can join Experience Project now! Username: Password Email Birthday Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Gender Select Male Female Trans* Already a member? Sign In By clicking "Sign Up", you confirm that you agree to the Terms of Service of Experience Project, Inc. Login Login to respond Username: Password: Keep me logged in Not a member? Sign Up Sign Up

subset: commoncrawl


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Summer Skate: Washington Capitals
Caps put trust in a young pair of goaltenders
Using the VUKOTA projection system of Puck Prospectus, Insider takes the temperature of key players on every NHL team. For a detailed explanation of Prospectus' proprietary GVT value metric, read more here.
Summer Skate -- Washington Capitals
Last season was a disappointment for Capitals fans as the team bowed out to the Montreal Canadiens in a seven-game series after holding a supposedly insurmountable 3-1 series lead. With last season behind them, the Capitals are looking to flat-out dominate the opposition on the scoreboard once again. The question, however, will be whether the team can prevent goals -- particularly in the playoffs. This year will be an important one for Alex Ovechkin & Co., but they're fortunate to have the added help of a young blueliner on the rise.
To see which key Capital is trending up and who is expected to decline in 2010-11, in addition to access to E.J. Hradek's blog, the NHL Draft Blog and all of Insider's NHL coverage, sign up today.
Become an insider and get access to all our articles and tools.View Insider Benefits »
Magazine subscribers: activate your Insider account.
The writers of Puck Prospectus break out their VUKOTA projection system to examine players trending up and sliding down on every NHL team. And in anticipation of training camp, E.J. Hradek dishes on an intriguing player that could have a big impact in 2010-11.


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How To Make Resolutions Into A Habit
To allow for optimal success, plan ahead for distractions that you know will occur. For example, if your battling a case of strep, don't try to sort through all the children's summer clothes or if I see a friend that is always up to date on the latest doings of everyone I know, I'll give her a heads up that I'm trying to work on my shmiras halashon.
Akst also talks about priming, which is basically faking it till you make it. This is the same idea as dressing professionally one level higher then your pay grade. In the realm of household organizing, read books about de-cluttering, and ask organized people for advice. Eventually, the ideas will sink in and take effect!
When you are meeting your goals, isolate and focus on the pleasure of achievement, of the quiet calm that organization brings. Articulate that pleasure out loud to yourself and to others. Success breeds success, like mitzvah goreres mitzvah. This will encourage future behaviors, which leads to force of habit. Hopefully, before long, the positive behaviors I yearn for will become second nature.
About the Author: Pnina Baim holds a B.S. in Health and Nutrition from Brooklyn College and an MS.edu from Yeshiva University's Azrieli Program. She works as a nutritionist, a certified lactation consultant, a home organizer, and in her free time writes as much as possible. She is the author of the Young Adult novels, Choices, A Life Worth Living (featured on Dansdeals and Jew In The City) and a how-to book for the Orthodox homemaker, Sing While You Work. The books are available at amazon.com. Pnina is available for speaking engagements and personal consulting. Contact her at firstname.lastname@example.com.
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If you promote any foreign religions, gods or messiahs, lies about Israel, anti-Semitism, or advocate violence (except against terrorists), your permission to comment may be revoked.


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Mets promote C-OF Rottino, send down RHP Schwinden
PITTSBURGH (AP) — The New York Mets have recalled catcher-outfielder Vinny Rottino from Triple-A Buffalo and optioned right-handed pitcher Chris Schwinden to the minor league team.
The Mets made the moves before Monday night's game at Pittsburgh.
The 32-year-old Rottino was with the Mets for a week earlier this month and went 0 for 4 in three games. He had a 20-game hitting streak this year in the minors.
Rottino played briefly for the Marlins last year and was with Milwaukee for parts of three seasons.
Schwinden was 0-1 with an 11.25 ERA in two starts for the Mets.


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Carbs Too High Questions
0 Answers
2 Views
I recently listened to a podcast on Robb wolfs paleo solution with Dr Perlmutter as the guest speaker. heres the link. http://robbwolf.com/2013/09/17/episode-200-guest-dr-perlmutter/ The guy seems to know his stuff & Robb... (more)
0 Answers
3 Views
I'm so lost!! I don't know what to do. My skin is always so clear when I do minimal carbs and sugar, also my sweating is to a minimum. However, when I am low carb I have an insane amount of hair loss - I would even take multivitamins (iodine,... (more)
Keep away from fruits and add some starches! Sweet potato etc.
1 Answers
5 Views
ok, so I have started logging my foods again because I am stalled. I am going with more customized foods too since some of them seem pretty off (heavy cream was totally incorrect). lets say that my % are sitting at 63% fat 19% protien and 17%... (more)
Popular Questions
Who wants to do Whole30 with me?
1 Answer
Paleo and Body Type Theory?
0 Answers
Macronutrient ratios, first month on Paleo
1 Answer


text: Sierra" is a 6 year old unregistered QH/ Arabian cross mare. 15.3hh. UTD on coggins, feet, wormer. She has been used primarily for trail riding, but we have done clinics and gymkhanas in the past. She is NOT a beginners horse. I will be very particular sbout who she goes to. Excellent ground manners, very intelligent and resonsive. She is "one person" horse, but once she trusts you, she will do anything for you. She needs an active rider. Great for vet, farrier, bathes and loads easily. Sierra adapts easily to new surroundings and gets along well with other horses. She is not "barn sour". I use a bitless bridle on her, she is very sensetive and responsive to it. Asking $900, will include halter and bitless bridle. For an extra $100, I will include her saddle, saddle pad, blanket, and other bridle. PM for more pics/information.


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The skin-flush sensors, which collect information about air pressure and density, much like a pitot tube on a conventional aircraft, provide angle-of-attack and yaw data to the B-2's computerized flight control system. After heavy, lashing rains, water got into the sensors and caused them to give faulty readings to the flight control system, the official said. As a result, the aircraft's computers determined—based on the bogus data—that the aircraft was in an improper attitude and corrected automatically. The B-2 made a sudden pitch-up and yaw that was not commanded by the pilot. The aircraft quickly stalled, became unrecoverable, and the crew of two ejected.
Moist air most likely caused the US Air Force to lose one of its prized Northrop Grumman B-2 bombers earlier this year, a loss calculated at $1.4 billion, the US Air Force reported on 5 June.
During a takeoff on a Guam runway on 23 February, moisture contamination on the fly-by-wire B-2's air data sensors threw off the tailless bomber's sensitive flight control system. (See video of the crash here.)
This is edited together from US Air Force video and reconstruction animation of the Northrop Grumman B-2 crash at Guam on February 23, 2008. The crash was caused by moisture in the air-data pressure sensors - a known problem, with a known fix that was never written down


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Are you José D González?Claim your profile
Publications (14)117.28 Total impact
- [Show abstract] [Hide abstract]
ABSTRACT: The management of pregnant women with acute promyelocytic leukemia (APL) is a challenge with limited evidence-based information available. We are reporting a series of 14 consecutive pregnant women with APL who were registered in the PETHEMA Data Centre between 1996 and 2012. APL was diagnosed during early pregnancy in five women, late pregnancy in seven, and two additional patients after delivery in an extremely poor clinical condition (pulmonary and cerebral hemorrhage). Eleven of the 12 patients eligible for induction therapy with all-trans retinoic acid and idarubicin achieved complete remission (CR 92 %) and are still in the first CR. All early pregnancies ended in abortion (four induced and one spontaneous), with four of them achieving CR. Eight of nine women in late pregnancy delivered a healthy infant (six cesarean section and two vaginal delivery). All eight babies developed normally. Our results confirm a high cure rate for pregnant women with APL who received all-trans retinoic acid and idarubicin for induction therapy, and an excellent outcome for babies when the disease is diagnosed during late pregnancy.
Article: Bortezomib-based induction therapy followed by intravenous busulfan-melphalan as conditioning regimen for newly diagnosed myeloma multiple patients.[Show abstract] [Hide abstract]
ABSTRACT: ABSTRACT Bortezomib-containing regimen followed by high-dose therapy and autologous stem cell transplantation (ASCT) is considered the standard of care for front-line therapy in younger patients with newly diagnosed multiple myeloma (MM). We have analysed the results of ASCT with iv busulfan 9.6 mg/kg and melphalan 140 mg/m(2)(ivBUMEL) preparative regimen in 47 patients with newly diagnosed MM who received bortezomib-based combinations as pre-transplant induction. Overall response rate and complete response after transplant were 100% and 49, respectively. With a median follow-up of 24.5 months, median overall survival and progression free survival have not been reached. Mucositis and febrile neutropenia were the most frequent toxicities observed. No case of sinusoidal obstruction syndrome was observed and there was not transplant-related mortality. These results suggest that front-line induction therapy with a bortezomib-based combination followed by ASCT with ivBUMEL is an effective and well-tolerated therapeutic approach for transplant eligible patients with MM. (Clinicaltrials.gov identifier: NCT00804947).
Article: Impact of prior rituximab on outcomes of autologous stem-cell transplantation in patients with relapsed or refractory aggressive B-cell lymphoma: A multicentre retrospective Spanish group of lymphoma/autologous bone marrow transplant study[Show abstract] [Hide abstract]
ABSTRACT: The use of highly effective rituximab-containing therapy for treating diffuse large B-cell lymphoma (DLBCL) makes it more difficult to salvage relapsed or refractory patients. Autologous stem-cell transplantation (ASCT) is the reference treatment for these patients, but the impact of previous exposure to rituximab on the subsequent results of ASCT remains unknown. We analysed 248 patients with relapsed or refractory DLBCL or grade 3B follicular lymphoma pre-treated with rituximab as part of first-line therapy (R+ group) who received ASCT, in comparison with a control group of 127 patients without previous exposure to rituximab (R- group). The complete remission (CR) rates were similar in both groups. Multivariate analysis identified age-adjusted International Prognostic Index at diagnosis, extranodal involvement and disease status at transplant, and the number of previous chemotherapy lines as independent factors with a negative influence on CR rate. Compared with R- patients, those in the R+ group had a significantly better progression-free survival (63% vs. 48% at 5 years) and overall survival (72% vs. 61% at 5 years). This observation was independent of other prognostic factors that affected these outcomes. In conclusion, ASCT is no less effective in patients with relapsed or refractory aggressive B-cell lymphoma pre-treated with first-line rituximab-containing therapy than in rituximab-naive patients.
Article: Intravenous Busulfan and Melphalan as a Conditioning Regimen for Autologous Stem Cell Transplantation in Patients with Newly Diagnosed Multiple Myeloma: A Matched Comparison to a Melphalan-Only Approach[Show abstract] [Hide abstract]
ABSTRACT: Melphalan 200 mg/m(2) (MEL200) is the standard conditioning regimen administered to newly diagnosed patients with multiple myeloma (MM) undergoing autologous stem cell transplantation (ASCT). Few alternatives have been explored in order to improve the antimyeloma activity of this conditioning. We compare i.v. busulfan (BU) 9.6 mg/kg and MEL 140 mg/m(2) (MEL140) versus MEL200 mg/m(2) as a conditioning regimen before ASCT for newly diagnosed patients with MM. For this purpose, 51 patients receiving i.v. BU plus MEL were compared to 102 patients receiving MEL200 mg/m(2) in a 1:2 matched control analysis. Matching criteria included age, clinical stage at diagnosis, and response to induction therapy. No differences in the overall and complete response (CR) rates were observed after ASCT between both groups. After a median follow-up of 63 and 50 months in control and BU plus MEL groups, progression-free survival (PFS) was 24 and 33 months, respectively (P = .10). Most frequent toxicities included mucositis and febrile neutropenia in both groups. No case of sinusoidal obstruction syndrome was observed. Transplant-related mortality was 4% and 2% in BU plus MEL and control groups, respectively. ASCT conditioned with i.v. BU plus MEL may be considered an effective and well-tolerated alternative to a MEL-only approach as a conditioning regimen for patients with MM who are candidates for ASCT. (Clinicaltrials.gov identifier: NCT00560053 and NCT00804947.).
Article: Clinical significance of CD56 expression in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based regimens[Show abstract] [Hide abstract]
ABSTRACT: The expression of CD56 antigen in acute promyelocytic leukemia (APL) blasts has been associated with short remission duration and extramedullary relapse. We investigated the clinical significance of CD56 expression in a large series of patients with APL treated with all-trans retinoic acid and anthracycline-based regimens. Between 1996 and 2009, 651 APL patients with available data on CD56 expression were included in 3 subsequent trials (PETHEMA LPA96 and LPA99 and PETHEMA/HOVON LPA2005). Seventy-two patients (11%) were CD56(+) (expression of CD56 in ≥ 20% leukemic promyelocytes). CD56(+) APL was significantly associated with high white blood cell counts; low albumin levels; BCR3 isoform; and the coexpression of CD2, CD34, CD7, HLA-DR, CD15, and CD117 antigens. For CD56(+) APL, the 5-year relapse rate was 22%, compared with a 10% relapse rate for CD56(-) APL (P = .006). In the multivariate analysis, CD56 expression retained the statistical significance together with the relapse-risk score. CD56(+) APL also showed a greater risk of extramedullary relapse (P < .001). In summary, CD56 expression is associated with the coexpression of immaturity-associated and T-cell antigens and is an independent adverse prognostic factor for relapse in patients with APL treated with all-trans-retinoic acid plus idarubicin-derived regimens. This marker may be considered for implementing risk-adapted therapeutic strategies in APL. The LPA2005 trial is registered at http://www.clinicaltrials.gov as NCT00408278.
Article: Therapy-Related Myeloid Neoplasms in Patients With Acute Promyelocytic Leukemia Treated With All-Trans-Retinoic Acid and Anthracycline-Based Chemotherapy[Show abstract] [Hide abstract]
ABSTRACT: We analyzed the incidence, risk factors, and outcome of therapy-related myeloid neoplasms (t-MNs) in patients with acute promyelocytic leukemia (APL) in first complete remission (CR). From 1996 to 2008, 1,025 patients with APL were enrolled onto three sequential trials (LPA96, LPA99, and LPA2005) of the Programa Español para el Tratamiento de Enfermedades Hematológicas and received induction and consolidation therapy with all-trans-retinoic acid (ATRA) and anthracycline-based chemotherapy. Seventeen of 918 patients who achieved CR developed t-MN (10 with < 20% and seven with > or = 20% of bone marrow blasts) after a median of 43 months from CR. Partial and complete deletions of chromosomes 5 and 7 (nine patients) and 11q23 rearrangements (three patients) were the most common cytogenetic abnormalities. Overall, the 6-year cumulative incidence of t-MN was 2.2%, whereas in low-, intermediate-, and high-risk patients, the 6-year incidence was 5.2%, 2.1%, and 0%, respectively. Multivariate analysis identified age more than 35 years and lower relapse risk score as independent prognostic factors for t-MN. The median overall survival time after t-MN was 10 months. t-MN is a relatively infrequent, long-term, and severe complication after first-line treatment for APL with ATRA and anthracycline-based regimens. Therapeutic strategies to reduce the incidence of t-MN are warranted.
Article: Sanz, M. A. et al. Risk-adapted treatment of acute promyelocytic leukemia based on all-trans retinoic acid and anthracycline with addition of cytarabine in consolidation therapy for high-risk patients: further improvements in treatment outcome. Blood 115, 5137-5146[Show abstract] [Hide abstract]
ABSTRACT: A risk-adapted strategy based on all-trans retinoic acid (ATRA) and anthracycline monochemotherapy (PETHEMA LPA99 trial) has demonstrated a high antileukemic efficacy in acute promyelocytic leukemia. We designed a new trial (LPA2005) with the objective of achieving stepwise improvements in outcome. Between July 2005 and April 2009, low- and intermediate-risk patients (leukocytes < 10 x 10(9)/L) received a reduced dose of mitoxantrone for the second consolidation course, whereas high- risk patients younger than 60 years of age received cytarabine combined with ATRA and idarubicin in the first and third consolidation courses. Of 372 patients attaining complete remission after ATRA plus idarubicin (92.5%), 368 proceeded to consolidation therapy. For low- and intermediate-risk patients, duration of neutropenia and thrombocytopenia and hospital stay were significantly reduced without sacrificing antileukemic efficacy, compared with the previous LPA99 trial. For high-risk patients, the 3-year relapse rate was significantly lower in the LPA2005 trial (11%) than in the LPA99 (26%; P = .03). Overall disease-free survival was also better in the LPA2005 trial (P = .04). In conclusion, the lower dose of mitoxantrone resulted in a significant reduction of toxicity and hospital stay while maintaining the antileukemic activity, and the combination of ATRA, idarubicin, and cytarabine for high-risk acute promyelocytic leukemia significantly reduced the relapse rate in this setting. Registered at http://www.clinicaltrials.gov as NCT00408278.
Article: Additional chromosome abnormalities in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy[Show abstract] [Hide abstract]
ABSTRACT: Acute promyelocytic leukemia is a subtype of acute myeloid leukemia characterized by the t(15;17). The incidence and prognostic significance of additional chromosomal abnormalities in acute promyelocytic leukemia is still a controversial matter. Based on cytogenetic data available for 495 patients with acute promyelocytic leukemia enrolled in two consecutive PETHEMA trials (LPA96 and LPA99), we analyzed the incidence, characteristics, and outcome of patients with acute promyelocytic leukemia with and without additional chromosomal abnormalities who had been treated with all-trans retinoic acid plus anthracycline monochemotherapy for induction and consolidation. Additional chromosomal abnormalities were observed in 140 patients (28%). Trisomy 8 was the most frequent abnormality (36%), followed by abn(7q) (5%). Patients with additional chromosomal abnormalities more frequently had coagulopathy (P=0.03), lower platelet counts (P=0.02), and higher relapse-risk scores (P=0.02) than their counterparts without additional abnormalities. No significant association with FLT3/ITD or other clinicopathological characteristics was demonstrated. Patients with and without additional chromosomal abnormalities had similar complete remission rates (90% and 91%, respectively). Univariate analysis showed that additional chromosomal abnormalities were associated with a lower relapse-free survival in the LPA99 trial (P=0.04), but not in the LPA96 trial. However, neither additional chromosomal abnormalities overall nor any specific abnormality was identified as an independent risk factor for relapse in multivariate analysis. The lack of independent prognostic value of additional chromosomal abnormalities in acute promyelocytic leukemia does not support the use of alternative therapeutic strategies when such abnormalities are found.
Article: Central nervous system involvement at first relapse in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy without intrathecal prophylaxis[Show abstract] [Hide abstract]
ABSTRACT: The prevalence of and risk factors for central nervous system recurrence in patients with acute promyelocytic leukemia are not well established and remain a controversial matter. Between 1996 and 2005, 739 patients with newly diagnosed acute promyelocytic leukemia enrolled in two consecutive trials (PETHEMA LPA96 and LPA99) received induction therapy with all-trans retinoic acid and idarubicin. Consolidation therapy comprised three courses of anthracycline monochemotherapy (LPA96), with all-trans retinoic acid and reinforced doses of idarubicin in patients with an intermediate or high risk of relapse (LPA99). Central nervous system prophylaxis was not given. Central nervous system relapse was documented in 11 patients. The 5-year cumulative incidence of central nervous system relapse was 1.7% (LPA96 3.2% and LPA99 1.2%; p=0.09). The cumulative incidence was 0%, 0.8%, and 5.5% in low-, intermediate-, and high-risk patients, respectively. Relapse risk score (p=0.0001) and the occurrence of central nervous system hemorrhage during induction (5-year cumulative incidence 18.7%, p=0.006) were independent risk factors for central nervous system relapse. This study shows a low incidence of central nervous system relapse in patients with acute promyelocytic leukemia following therapy with all-trans retinoic acid and anthracycline without specific central nervous system prophylaxis. Central nervous system relapse was significantly associated with high white blood cell counts and prior central nervous system hemorrhage, which emerged as independent prognostic factors.
Article: Single daily dose of intravenous busulfan and melphalan as a conditioning regimen for patients with multiple myeloma undergoing autologous stem cell transplantation: A phase II trial[Show abstract] [Hide abstract]
ABSTRACT: We evaluated the toxicity and outcome of a conditioning regimen comprising intravenous (iv) busulfan (BU) and melphalan (MEL) in 55 patients (median age, 61 years; range, 34-71) with multiple myeloma (MM) undergoing autologous stem-cell transplantation (ASCT). In 49 patients, this was the first ASCT. At transplant, 3 patients were in complete response (CR), 8 in near CR (nCR) and 30 in partial response (PR). The conditioning regimen comprised ivBU (3.2 mg/kg in a single daily dose, days -5 to -3) and MEL (140 mg/m(2), day -2). Mucositis was the most frequent non-hematopoietic toxicity (47 patients). No patient developed sinusoidal occlusive syndrome. Febrile events were observed in 46 patients and were the cause of death in two (3.6%) transplant-related deaths. With a median follow-up of 15 months, 27 patients achieved CR/nCR (11 CR) and 21 a PR. The one-year actuarial overall and progression-free survival rates are 96% and 87%, respectively. This ivBU-containing regimen is associated with an acceptable toxicity and a high-response rate.
Article: Differentiation syndrome in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline chemotherapy: Characteristics, outcome, and prognostic factors[Show abstract] [Hide abstract]
ABSTRACT: Differentiation syndrome (DS) can be a life-threatening complication in patients with acute promyelocytic leukemia (APL) undergoing induction therapy with all-trans retinoic acid (ATRA). Detailed knowledge about DS has remained limited. We present an analysis of the incidence, characteristics, prognostic factors, and outcome of 739 APL patients treated with ATRA plus idarubicin in 2 consecutive trials (Programa Español de Tratamientos en Hematología [PETHEMA] LPA96 and LPA99). Overall, 183 patients (24.8%) experienced DS, 93 with a severe form (12.6%) and 90 with a moderate form (12.2%). Severe but not moderate DS was associated with an increase in mortality. A bimodal incidence of DS was observed, with peaks occurring in the first and third weeks after the start of ATRA therapy. A multivariate analysis indicated that a WBC count greater than 5 x 10(9)/L and an abnormal serum creatinine level correlated with an increased risk of developing severe DS. Patients receiving systematic prednisone prophylaxis (LPA99 trial) in contrast to those receiving selective prophylaxis with dexamethasone (LPA96 trial) had a lower incidence of severe DS. Patients developing severe DS showed a reduced 7-year relapse-free survival in the LPA96 trial (60% vs 85%, P = .003), but this difference was not apparent in the LPA99 trial (86% vs 88%).
Article: Risk-adapted treatment of acute promyelocytic leukemia with all-trans retinoic acid and anthracycline monochemotherapy: Long-term outcome of the LPA 99 multicenter study by the PETHEMA Group[Show abstract] [Hide abstract]
ABSTRACT: A previous report of the Programa de Estudio y Tratamiento de las Hemopatías Malignas (PETHEMA) Group showed that a risk-adapted strategy combining all-trans retinoic acid (ATRA) and anthracycline monochemotherapy for induction and consolidation in newly diagnosed acute promyelocytic leukemia results in an improved outcome. Here we analyze treatment outcome of an enlarged series of patients who have been followed up for a median of 65 months. From November 1999 through July 2005 (LPA99 trial), 560 patients received induction therapy with ATRA plus idarubicin. Patients achieving complete remission received 3 courses of consolidation followed by maintenance with ATRA and low-dose chemotherapy. The 5-year cumulative incidence of relapse and disease-free survival were 11% and 84%, respectively. These results compare favorably with those obtained in the previous LPA96 study (P = .019 and P = .04, respectively). This updated analysis confirms the high antileukemic efficacy, low toxicity, and high degree of compliance of a risk-adapted strategy combining ATRA and anthracycline monochemotherapy for consolidation therapy.
Article: Causes and prognostic factors of remission induction failure in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and idarubicin[Show abstract] [Hide abstract]
ABSTRACT: An understanding of the prognostic factors associated with the various forms of induction mortality in patients with acute promyelocytic leukemia (APL) has remained remarkably limited. This study reports the incidence, time of occurrence, and prognostic factors of the major categories of induction failure in a series of 732 patients of all ages (range, 2-83 years) with newly diagnosed APL who received all-trans retinoic acid (ATRA) plus idarubicin as induction therapy in 2 consecutive studies of the Programa de Estudio y Tratamiento de las Hemopatias Malignas (PETHEMA) Group. Complete remission was attained in 666 patients (91%). All the 66 induction failures were due to induction death. Hemorrhage was the most common cause of induction death (5%), followed by infection (2.3%) and differentiation syndrome (1.4%). Multivariate analysis identified specific and distinct pretreatment characteristics to correlate with an increased risk of death caused by hemorrhage (abnormal creatinine level, increased peripheral blast counts, and presence of coagulopathy), infection (age>60 years, male sex, and fever at presentation), and differentiation syndrome (Eastern Cooperative Oncology Group [ECOG] score>1 and low albumin levels), respectively. These data furnish clinically relevant information that might be useful for designing more appropriately risk-adapted treatment protocols aimed at reducing the considerable problem of induction mortality in APL.
Article: Treatment With All-Trans Retinoic Acid and Anthracycline Monochemotherapy for Children With Acute Promyelocytic Leukemia: A Multicenter Study by the PETHEMA Group[Show abstract] [Hide abstract]
ABSTRACT: To analyze the simultaneous combination of all-trans retinoic acid (ATRA) and anthracycline monochemotherapy for children with acute promyelocytic leukemia (APL). Since November 1996, 66 children (younger than 18 years) with genetically proven APL received induction therapy with ATRA and idarubicin. Consolidation therapy consisted of three courses of anthracycline monochemotherapy. After November 1999, patients with intermediate and high risk of relapse received consolidation therapy with ATRA and slightly reinforced doses of idarubicin. Maintenance therapy consisted of ATRA and low-dose mercaptopurine and methotrexate. Thirty-nine girls (59%) and 27 boys (41%) were included in this study. The WBC count at presentation was more than 10 x 10(9)/L in 26 patients (39%). Sixty-one children (92%) achieved complete remission (CR). Early deaths from hemorrhage and retinoic acid syndrome occurred in three patients and two patients, respectively. Toxicity was manageable during consolidation and maintenance therapy. No deaths in CR, clinical cardiomyotoxicity, or secondary malignancy occurred. Two patients had molecular persistence at the end of consolidation. Three clinical relapses and two molecular relapses were also observed. Apart from one molecular relapse, all these events occurred among children with hyperleukocytosis. The 5-year cumulative incidence of relapse was 17%, whereas disease-free and overall survival rates were 82% and 87%, respectively. A high incidence of hyperleukocytosis in children with APL was confirmed. Besides low toxicity and a high degree of compliance, a risk-adapted therapy combining ATRA and anthracycline monochemotherapy showed an antileukemic efficacy comparable to those previously reported with other chemotherapy combinations in children.
Top Journals
- Blood (4)
- Leukemia & lymphoma (2)
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- Journal of Clinical Oncology (1)
Universidad de Las Palmas de Gran CanariaLas Palmas, Canary Islands, Spain
Hospital Universitario Virgen del RocíoHispalis, Andalusia, Spain
Hospital Universitari i Politècnic la Fe
Valenza, Valencia, Spain
- Servicio de Hematología


text:
Anti Theft Troll Phone Trolls
by: YPSIO m.obile | 197
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text:
Matty Sutton, Reporter / / Lifestyle
SANDY and the Pink Ladies took time out from treading the boards to do a bit of training.
The stars of musical production Grease, which is currently on at the King's Theatre, ran in Bellahouston Park in readiness for the Bupa Great Women's 10K on May 11.
Every year the event draws thousands of women to take part in the race on Glasgow's South Side.
Andy Mitchelmore, from organiser's Nova International, said: "The Bupa Great Women's 10K is a fantastic event and with six weeks to go there is plenty of time to sign up, get training and be part of it.
"It is amazing to see so many women running together as well as all the spectators who come out to cheer everyone on along the route.
"We will watch out for the Pink Ladies on May 11. Hopefully there will be some T-Birds waiting to cheer them over the finish line."
Visit www.greatrun.org/womens10k to enter.
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On February 26, 2016, Lucas County Job and Family Services (including buildings at 3210 Monroe Street, 1301 Monroe Street and 701 Adams Street) will be closed for an agency-wide training. Agency workers stationed throughout the community will also attend this training and will be unavailable on this day.
ARE YOU PREPARED FOR EMERGENCIES? Being prepared means being equipped with the proper supplies you may need in the event of an emergency or disaster. Keep your supplies in an easy-to-carry emergency preparedness kit that you can use at home or take with you in case you must evacuate. The list of supplies can be found at this link - American Red Cross
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The hugely successful BLACKEST NIGHT action figure line continues! Included in this seventh installment of the series are: Black Lantern Superman, back from the dead - again; Sinestro Corps Member Arkillo, dissenter defeated, forever forced to wear his traitorous tongue around his neck; Red Lantern Mera, with a rage-filled heart, she allows the Red Ring of Power to drown her; Black Lantern Terra with Scar, resurrected to prey on the hearts of her former team members, Terra teams with near-death survivor Scar in an effort to eradicate all emotion in the Universe.
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Carahsoft recognizes that our employees are our greatest asset and an important part of our formula for success. Our culture is built on integrity, loyalty, intelligence, and a strong work ethic. Simply put, Carahsoft is a great place to work.
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XKCD has kindly provided a new mnemonic device for remembering the names and order of the eight planets in our solar system, and it has a Christmas theme to it. Click through to read several other mnemonic aids in the same cartoon.
Christmassy Planetary Mnemonic
December 21, 2011 by James F. McGrath 2 Comments
Filed Under: astronomy, Bible, Christianity, science Tagged With: cartoon, humor, mnemonic, mnemonics, my very educated mother just served us nine pickles, planets, XKCD 2 Comments
Related posts from Exploring Our Matrix:
- Gary
Didn't see the one I learned as a kid. Mother very thoughtfully (terra) made a (asteroids) jelly sandwich under no protest. Yeah – in those days pluto was a planet. Progress sucks some times. And a frisbee is NOT a frisbee!….it is a pluto plater. From someone who was a kid in the 50′s.


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Archive for Ryan Callahan
More Callahan contract rumorsPosted by: | Comments
I hope you're all ready for a long three days of endless Ryan Callahan rumors. As the trade deadline approaches on Wednesday, we are going to hear endless "Callahan to [insert team here]" rumors, even more "Callahan's updated demands" rumors, and some 'Glen Sather ups his offer" rumors. This time around, we have a few new rumors, courtesy of Pierre LeBrun.
LeBrun stated that both sides have moved off their initial demands. The Rangers are holding firm at six years and $36 million, while the Callahan camp has come down to six years and "south of $6.5 million." I mentioned on Twitter yesterday that the Girardi term (six years) means the Rangers are going to go to six years for Cally. There's a deal to be made here, whether or not you agree with the term or dollars.
New Girardi deal helps Rangers with organisational weaknessPosted by: | Comments
For several years the Rangers had a relatively steady flow of defensive prospects make it to the NHL through the system. Whether it was Michael Del Zotto, Marc Staal, Ryan McDonagh, Mike Sauer or Girardi himself, the Rangers were able to supplement the NHL roster with cost effective home grown talent. Recently, there have been concerns of the talent approaching the NHL level.
With the relatively slow progress made by Dylan McIlrath (who still has time on his side) and the unknown NHL projections of Brady Skjei and Calle Andersson, the Rangers don't have the ability to promote from within. Perhaps Conor Allen aside, there is very little that could step up in short notice.
The Rangers cannot afford to trade Derek StepanPosted by: | Comments
It's the time in hockey season where rumours are rampant. Ryan Callahan is apparently already half way out the door, the Rangers are apparently in bed with Martin St Louis and apparently Glen Sather will 'check in' on Ryan Kesler. All of these rumours have legs to some degree, so when you hear Derek Stepan's name mooted as a piece Vancouver may want back for any Kesler deal, it does make you question the moving pieces.
The Rangers, for the long term, cannot afford to move Stepan. Not just because he is a home grown, quality player but because too much change is never a good thing. Consider the likely departure of Brad Richards in the summer. Consider also the expiring contracts of Brian Boyle and Dominic Moore. Then throw into the mix the still uncertain future of Derick Brassard (How much is enough? Is he even kept?). There is a legitimate chance in all of this then that the Rangers entire center ice unit changes. Until you realize no team in their right mind would change an entire position over one deadline/off-season. Right, Glen?…
The lines Alain Vigneault found success with are about to be changed, probably for goodPosted by: | Comments
I still can't get used to Alain Vigneault's steady line combinations after four years of John Tortorella's incessant juggling, but Vigneault has stuck with the same combinations for quite some time now. It's worth nothing that the Rangers finally turned a corner this season thanks in no small part to the team's balance and chemistry up front. Mats Zuccarello has been the team's best forward so far this season and a key cog in Vigneault's formula, but with him lost for likely another week or two (not to mention the upcoming trade deadline), Vigneault will be forced to rejigger his preferred trios.
Throw in the fact that winger Derek Dorsett is ready to return from a broken fibula and 20-year-old J.T. Miller, who has been dominant in the AHL, was recalled last night, and it's tough to predict what Vigneault will end up with. It's probably most likely that Vigneault will be forced to try several different new looks – which might not be settled by the trade deadline in three games, throwing us back to square one.
Boomer ramps up Callahan trade discussionPosted by: | Comments
In case you missed it, Boomer Esiason sent Twitter into a craze over the weekend when he posted a series of tweets alluding that Ryan Callahan will be traded before the deadline. What started as a more casual conversation with ambiguous thoughts and 'gut feelings' turned in to something much more.
By the time he was done responding to fans he had crossed out potential trade partners as well as specific trade candidates. In other words, he's claiming to know something. This whole thing was basically positioned as something where both parties already agree upon the framework of a deal. For all of his tweets, click here.
Now I know some of you may ask, how would a former NFL QB get inside scope on the Rangers? It's a fair question and the answer doesn't seem obvious, at least not at first.
Could the Rangers go for it all, this summer?Posted by: | Comments
If you're a cup half full kind of person, assume for a minute that both Ryan Callahan and Dan Girardi sign back up with the Rangers and the core remains intact. Let's also assume for a moment that Anton Stralman sticks around for a reasonable cost, and all of a sudden the Rangers fine core remain together; losing 'just' Brad Richards who is surely off to pastures new.
With the NHL salary cap going up this summer –and with the Rangers likely to have some serious cap room to play with– the opportunity (or danger?) to go out and entice a major free agent or two is there. Of course, most Rangers fans start getting anxious at the thought of Glen Sather having a blank cheque book. Sather's Achilles heel is his free agency history.
Dan Girardi and Anton Stralman represent the key to the Rangers spending ability this summer. The upcoming free agency period is absent of legitimate options on the blueline, unless you're happy to over commit to 36 year or 37 year olds. With Girardi and Stralman (hopefully) under wraps the Rangers retain one of the deepest defensive units in the league, allowing them to focus any spending up front, where there could be a few quality players available.
Identifying potential trade targets for Ryan CallahanPosted by: | Comments
Last night, news broke that TSN's Bob McKenzie joined the discussion about the possibility of trading Ryan Callahan. While McKenzie did not specifically state Cally would be traded, he alluded to the fact that he will either re-sign or be dealt by the trade deadline. I am sticking to my prediction that Cally re-signs, but when McKenzie says there's a chance Cally will be traded, you listen.
I again need to be on record: A team that is in the thick of things in the conference –and has a legitimate shot at representing the Eastern Conference this May/June– doesn't trade their captain. It doesn't happen. That said, McKenzie's comments have shifted things, and for the sake of argument, there are 29 teams that could use Cally's services. So let's go through these possibilities.
Why can't the Rangers come out of the East?Posted by: | Comments
Unfortunately, we were not able to get the goal breakdown last night since Dave was traveling for work, Chris was traveling for pleasure, Suit had a hockey game, Becky was working late, etc, etc. Check back later this afternoon for an abbreviated recap.
One of the chief arguments for trading Ryan Callahan and/or Dan Girardi is that the Rangers aren't a contender this year even with those veterans on board, so the team should trade one or both to set itself up for the future.
The organization has made it very clear that winning now is the goal, a philosophy many pessimistic fans don't agree with because they don't see the roster as talented enough to take home the ultimate prize. To me, that's the wrong way of looking at it.
Cally's "$7 million demands" are not that surprisingPosted by: | Comments
In case you missed it, Darren Dreger reported on TSN Insider yesterday that captain Ryan Callahan does not want seven years and $6 million, he wants $7 years at "between $6.5 million and $7 million." Dreger is not one to really mess around when it comes to rumors either.
Now before I go into my spiel about negotiations, step one in the process, et cetera et cetera, let's point out that this is just that: Step one in the process. Also, read this post.
All caught up? Relaxed a bit? Ok good. Let's point out the specifics of this demand, and why it really shouldn't be all that surprising to anyone. Remember, this is step one in the negotiations process.
Everything you need to know about the Dan Girardi/Ryan Callahan situationPosted by: | Comments
Throughout the year, there have been rumblings about trading Dan Girardi or Ryan Callahan. We've mostly been dismissive about them. Over the past two days, we've seen a big blowup in the rumors, and received a bunch of emails. So let's answer all of them:
Q: What exactly is going on?
Both Ryan Callahan and Dan Girardi are set to become unrestricted free agents at the end of the year, and both are due for relatively big pay increases. There have been rumblings –from multiple media members, including Bob McKenzie– that the Rangers are entertaining trade offers for both. The rumors are that they will trade them both instead of risking losing them for nothing. It seems that Girardi is the one who will most likely re-sign soon, but Cally's contract negotiations are not going well.
Q: What do they want in their next deals?


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Best Bastilla (2003)
Cafe Paprika
Bastilla is a Moroccan party food, but there's no reason you can't use it to celebrate everyday life. Made up of several layers of delicate, crisp phyllo dough filled with saffron-spiced chicken, onions, crushed almonds and herbs held together with an egg batter, bastilla is pan-cooked into a round pie and topped with powdered sugar and an ornamental design drawn in ground cinnamon. You may need to recalibrate your tastebuds to fully appreciate the true depth of these last flavors, which bring so much more to this dish than they would your average slice of French toast. Listed as an appetizer on Cafe Paprika's menu but easily a meal in itself, this is a festive dish worthy of fanfare.
More Awards from This Winner
Location Details
13160 E. Mississippi Ave.
Aurora CO 80012
Aurora CO 80012
More Food & Drink Awards
Best New RestaurantOpal
Best Celebrity ChefSean Kelly
Clair de Lune
Best Front-of-the-House CrewMizuna
Best Garde-Manger ManSeth Black
Clair de Lune


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UK MOBILE OPERATOR EE has announced that its first LTE smartphones will go on sale in the UK today, following last night's decision that it can roll out 4G services this year as planned.
Although they won't arrive with 4G speeds from the get go, the LTE enabled Iphone 5, Samsung Galaxy S3, HTC One XL and Huawei Ascend P1 are now available to order. Customers will first have to buy the phones on a 3G price plan with either Orange or T-Mobile before being upgrading to EE's 4G network, which it is promising will arrive "within weeks."
There's no word yet as to when the 4G LTE enabled Nokia Lumia 920 and Lumia 820 handsets will go on sale, although they are expected to arrive on the network in early November.
The price plan details remain a mystery too, and EE was unable to give us any further information. We can't help but think that this is because 4G LTE tariffs in the UK are going to have eye-watering prices, but we'll just have to wait and see.
Pippa Dunn, chief marketing officer at EE said, "We're delighted to now be offering our customers a range of 4G ready smartphones to choose from.
"Not only can they use their phones straight away on the UK's biggest 3G network, but they can also have the opportunity to be amongst the first to benefit from superfast 4G mobile speeds when we launch our EE brand." µ
Tags: 4G


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I have really been wanting to try a fancy blender. So I was thrilled when I heard that Kate n' Kaboodle is organizing a giveaway of a Blendtec Designer Series Wildside Total Blender that sells for $499!
I'm excited to be participating and bringing the chance to win this great prize to my readers! If you're a blogger, you can sign up for free here.


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Sponsored By
Preliminary Info: Maynard Was Driving On Wrong Side Of Route 32 Before CrashWaterford Police say it appears that a car driven by state senator Andrew Maynard was on the wrong side of the road, when it collided head-on with another vehicle.
State Senator Injured In One-Vehicle Crash
Arrest In Waterford Crash That Killed Three Family MembersState Police have made an arrest in a 4-vehicle crash on I-95 in Waterford last October that killed three people, including two children.
Leaking Valve Causes 'Unusual Event' At MillstoneThe Nuclear Regulatory Commission says a leaking relief valve has caused an ``unusual event'' declaration at Millstone Power Station.
West Nile Virus Returns
Father Of Wandering Child Arrested
Lawmaker Seeks To Require State To Consult Towns On ParksA southeastern Connecticut state lawmaker is introducing legislation to give local town officials and residents more of a say in the siting of state parks.
Meeting Planned For Proposed State Park In WaterfordThree state agencies plan to publicly introduce the team that will be working with the community on developing a new state park at the former Seaside Sanatorium in Waterford.
US Oversight Increased At Millstone Nuclear PlantThe Nuclear Regulatory Commission says it is stepping up oversight at Connecticut's nuclear plant following a safety violation.
State Probing Millstone Water Dumped Into LI SoundState environmental officials are taking a closer look at the impact of more than 2 billion gallons of water discharged into Long Island from Connecticut's nuclear plant.
Millstone Drill To Test Response To Intruders
US Regulators Rap Faulty Water Pump At Millstone Federal regulators say they could impose more inspections and greater oversight of Connecticut's nuclear power plant due to repeated problems with a critical water pump.


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Business SituationNCC Roads has a decentralized and locally managed infrastructure. Consequently lacking a global desktop standard, multitude of infrastructure providers as well as a large and heterogeneous OS/application portfolio.
SolutionAvanade worked with NCC to transform the NCC Roads IT infrastructure from the previously dispersed IT landscape into a managed, standardized and efficient platform supporting the NCC Roads strategic cornerstones; organic growth, acquisitions & divestments, increased productivity and efficient financing.
Avanade was responsible for designing and building the infrastructure based on SCCM 2007, Microsoft Vista, PKI, IAG as well as upgrading, consolidating and migrating Microsoft Exchange 2007 and Active Directory.
ResultsAvanade delivered the design and build phase for the One Roads platform project on time and on budget with very positive feedback from key stakeholders in the organization.
Avanade also ensured coordination with parallel security project to support common goal while providing support and integration with existing solutions.
Using Microsoft technology to migrate from a legacy system in order to modernise infrastructure while minimising business impact
Avanade provided the AFL with a platform to facilitate collaboration and to help lower communication costs
Avanade provided AIS staff with a content management system to ease communication and reduce web maintenance
Global corporate bank improves sales, account management and reporting


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Jul Topografie Series Patterns - Infinity Scarf is a similar pattern: 18 (4.5 sts. / inch) finished gauge, scarf garment, for women, worsted (19-20 sts/4 in) yarn gauge, and on size US 7 US needles. You may also like Dull Roar Patterns - Chevzam!, which is another similar pattern: scarf garment, for women, worsted (19-20 sts/4 in) yarn gauge, and malabrigo worsted suggested yarn.
You may enjoy taking a look at the The Fibre Company Terra Staggered Ladders Scarf, Madelinetosh Prairie Short Skeins Spring Leaves Lace Shawl, and Madelinetosh Tosh Merino Light Octopus's Garden Shawl kits all using Grace Akhrem Patterns.
Hopefully our suggested yarn options for Walt's Tangled Cables can help you come up with your next exciting new project idea!


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Protect What is Yours
From flatscreen TVs to laptops, from Persian rugs to works of art – many of your possessions are valuable and would cost money to replace. Protect what's precious to you with household insurance from Hollard and get financially covered for any loss or damage to your valuables.
Get a home insurance quote.
How to Work out If You Have Enough Household Insurance Cover
Would the cover amount enable you to replace lost, damaged or stolen goods? The correct amount should be what it would cost you to replace the insured item now, not what you originally paid for it.
Have you updated the value of your home and household contents recently? This is important as the cost to replace items is constantly increasing.
Does your household insurance cover keep track with inflation? Policies from Hollard do.
If you've taken precautions to secure your possessions, such as alarms and other security features, you should be rewarded for this with a lower premium.
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- Your cover amount is increased automatically on the anniversary date of your policy, by inflation and a linked percentage. This ensures that your contents are never under-insured - so you won't end up out of pocket.
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possessions inside your home, such as:
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We also provide coverage for items in your outbuildings, whether they're separate from your home or not.
- This home contents insurance policy covers damage to your household contents, whether by theft, an act of nature (such as lightning, storms, floods or snow), as well as damages caused by fire
- You get a fully hassle-free claims process
- Streamline the process by getting car and household insurance together: you also have access to car insurance from Hollard on the same policy
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You'll need to submit all the requested claims documents and supporting documents to us. To help you, a dedicated claims specialist can guide you through the process and let you know of any excess premiums payable. Supporting documents include:
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To make a Household Insurance claim
Read our easy to follow steps about how to make a household claim.
To update your Household Insurance policy
If you need to amend or renew your policy, please contact Hollard on the details listed below:
Email: firstname.lastname@example.com
Call us: 0861 010 203
To get a Household Insurance quote
Call us: 0861 360 360


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The 2011 Mini Copper S Countryman is a cute and flexible crossover that is a great option for small families, according to MotherProof.com contributor Sara Lacey. Continue reading her full review below, and check out the day's other top stories:
Honda to Honor Discounts on Sold-Out Models
2011 Saab 9-5, 2011-12 Volkswagen CC Earn IIHS Top Safety Pick
Recall Alert: 11,351 Chrysler, Dodge, Jeep Vehicles
Recall Alert: 2010-11 Porsche 911
What Does This Button Do?
2012 BMW Lineup: Ch-Ch-Changes
2012 Buick Regal GS Rated at 270 HP


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To view store specific pricing and availability please enter a zip and choose a store.
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Miner's Lady, The (Land of Shining Water) - eBook
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Product Description
Chantel can't deny the attraction that flares when she's with Dante. But when a tragedy occurs at the mine, is there any hope that the hatred that has simmered between these two families might be resolved? Or will Chantel's hope for love be buried amidst decades of misunderstanding?
Product Information
|Format: DRM Protected ePub
Vendor: Bethany House
Publication Date: 2013
Availability: In Stock
Series: Land of Shining Water
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Publisher's Description
When Chantel Panetta's younger sister claims to be in love with Orlando Calarco, Chantel knows there is no hope. The Panettas and Calarcos have been sworn enemies for decades, and young love cannot heal the deep wounds between the two iron-mining families. Yet, unable to resist Isabella's pleas, Chantel agrees to help her sister spend time with Orlando...only to have a run-in with Dante, Orlando's brother. The older, more handsome one.
Chantel can't deny the attraction that flares when she's with Dante. But when a tragedy occurs at the mine, is there any hope that the hatred that has simmered between these two families might be resolved? Or will Chantel's hope for love be buried amidst decades of misunderstanding?
Author Bio
Product Reviews
Ginger5 Stars Out Of 5The Miner's LadyAugust 4, 2015GingerQuality: 0Value: 0Meets Expectations: 0Loved it
Joy to read5 Stars Out Of 5The Miner's Lady,Land of Shining Water Series #3August 4, 2015Joy to readQuality: 5Value: 5Meets Expectations: 5This book, along with the other ones in this series, was one of the best reads I have purchased for a long time. The characters had depth and the story was multi-faceted, not just a boy-meets-girl-fights love-gives-in kind of "plot"
When I was reading it, I could hardly put it down!!
Top marks once again to Tracie Peterson who is one of my favorite authors.
WilaniFranklin, NCAge: 55-65Gender: female5 Stars Out Of 5Great ReadAugust 24, 2014WilaniFranklin, NCAge: 55-65Gender: femaleQuality: 5Value: 5Meets Expectations: 5Another great book by Tracie Peterson! One of the things that I love about Tracie's books is the way the Gospel and Spiritual Truths are woven throughout the book. This book was no exception. I loved this book even though it did have some dark moments. During these dark moments she had a way of weaving light into the story. Here are a couple quotes that stood out to me. "We will ask God for His help with confidence and trust in Him. No matter what happens God is still in control." and "God is still God even when all hope seems lost and nothing in this world is going our way. He may not always do things as we think He should, but He is perfect and holy and His ways are as well" I have fallen in love with this family and I would love to read more of them.
alwaysreadingAge: 55-65Gender: female4 Stars Out Of 5Terrific readFebruary 8, 2014alwaysreadingAge: 55-65Gender: femaleQuality: 4Value: 4Meets Expectations: 4The miner's lady is the third book in Traci Peterson's Land of Shinning Water series. It has no connection to the first two book other than it takes place in Minnesota. It is a love story of two family from Italy who come to America and bring with them their traditions, love of family and also a 100 year old feud.
Orlando Caraco and Isabella Panetta have fallen in love and Isabella older sister Chantel will do whatever she can to help the young couple elope. Unfortunately that mean's running interference with Orlando's devastating handsome older brother Dante. Things go from bad to worse when Chantel realizes that she has fallen in love with him.
Nonna Barbota really stole the show for me. I found this character to be most engaging. She really brought to life the qualities that I think most Christians strive to have. The way she forged ahead with what she knew was the right thing God wanted her to do regardless of what anyone else thought was truly impressive.
I have to admit I was taken by surprise by this book. Being the subject of mining, I wasn't too excited about reading this, but after the first two chapters I couldn't really put it down. There were several places that I laughed out loud and several places that I found myself tearing up. I love a book that can bring out different emotions in me.
nomer15Gender: female4 Stars Out Of 5January 11, 2014nomer15Gender: female"The Miner's Lady" by Tracie Peterson tells the tale of two families, the Panettas and the Calarcos. Residing in the mining community of Ely, Minnesota, the families carry on a decades-old feud bought over from their native Italy. When Isabella Panetta and Orlando Calarco announce their love for one another and their intention to marry, it leads to a story of how forgiveness can overcome any obstacle. In their individual quests to save their siblings from falling into harm as a result of their love for one another, Chantel Panetta and Dante Calarco embark on their own journey of love and forgiveness overcoming all.
The characters are engaging and believable, although I did find some of the dialogue to be a bit over-the-top for the time period the story is set in. Being originally from Minnesota, I've really enjoyed this entire series since it's based in my home state. Peterson is one of my favorite authors who rarely fails to disappoint. This whole series has been great fun to read, and this conclusion to the trilogy truly fits the bill.
(I've received this complimentary book from Bethany House Publishers through the Book Blogger program in exchange for a review. A positive review was not required and the views expressed in my review are strictly my own.)
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Some replica parts had to be obtained in the last two years: Huge glass panes, one-centimeter (0.39 inch) thick, were made in Belgium while the white linoleum that originally covered the floor was provided by the same German company that made it more than 80 years ago.
Fritz and Grete Tugendhat lived in the villa with their three children for eight years in the 1930s. Grete said she fell in love with it "from the first moment."
One of their daughters, Daniela Hammer-Tugendhat, now works as a professor of art history at the University of Applied Arts in Vienna.
"For me, this is actually the most beautiful interior room in modern architecture," she told AP. "Usually, it's only in old churches that a room has such a meditative effect."
Hammer-Tugendhat and her husband are leading members of an international committee of experts overseeing the villa's reconstruction, co-financed by the city, EU funds and the state.
The villa's central living open space has its south and east walls made of huge steel-frame windows that allow a magnificent view of Brno's historical monuments and connect rather than separate the building with the garden.
Mies van der Rohe also designed the furniture, including his famed chairs, and equipped the building with air conditioning and security systems.
In 1938, the Tugendhats had to leave the country to escape the Nazis, first for Switzerland and later for Venezuela.
Mies van der Rohe, whose work did not meet Hitler's taste for monumental architecture, also fled the Nazis, purportedly using his brother's passport to get out of Germany. He settled in Chicago to work for the Illinois Institute of Technology and designed a number of significant buildings in his new land, including Lake Shore Apartments in Chicago, the Farnsworth House in Plano, Illinois, the Seagram Building in New York City and Martin Luther King Jr. Memorial Library in Washington D.C. He died in 1969.
The Gestapo seized the building after invading Czechoslovakia and — insensitive to the original design — made changes, including erecting several extra walls inside and outside and increasing the height of the chimney.
All but one of the large windows was smashed by Allied bombings.
During the liberation by the Red Army in 1945, the living space was used as a stable for the officers' horses — and all but one of the shelves of a huge ebony bookcase was burned.
The Communists, who took power here in 1948, tried their hand at renovating the villa in the 1980s — but did more harm than good. The original bathroom equipment and the sole remaining pane of a wall of glass were destroyed because they didn't fit their plan.
The deal that split Czechoslovakia into the Czech Republic and Slovakia in 1992 was signed in the villa, adding to its historical significance.
The idea to restore the villa dates back to 2001 when UNESCO declared it a world heritage site. Copies of original plans and photographs from the MoMA in New York City as well documents from family and from Brno archives, including pictures taken by Fritz Tugendhat, were used to help restore the building.
City officials now are trying to buy the original pieces of furniture from the families that own them.
"It would be something extraordinary to get them all," said Brno mayor Roman Onderka.
A grand opening is scheduled for Feb. 29 and the villa will be reopen to the public March 6. Officials said they have already been flooded by requests from potential visitors.
APTN videojournalist Philipp-Moritz Jenne in Vienna contributed to this report
If you go:
VILLA TUGENDHAT: Brno, Czech Republic; http://www.tugendhat.eu/en/. Opens to the public March 6. Brno has an international airport and is also accessible by train, bus or car from Prague, about 200 miles away.
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For those that can't do apps, this is by request and is a indexed PDF file. Look up a city and find all of the Truck Stops with map links. Download it and take it with you. $6.97 Truck Stop PDF.


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text:
Also Thursday, Yediot ran a story about Beck's Restoring Courage Rally beneath the Temple Mount in Jerusalem. The headline read, "Glenn Beck's Messianic Show."
In general, the Israeli media responded to Beck's visit to Israel either as a non-event, or they distorted who Beck is and what he is trying to do. Thursday's print edition of Ma'ariv sufficed with a photograph from Beck's rally in Jerusalem the previous day.
By casting Beck's visit as insignificant, Ma'ariv disserved its readers. Beck is one of the most influential media personalities in the US today.
Unlike the leftist public intellectuals such as New York Times columnist Tom Friedman who are celebrated and obsessively covered by the Israeli media, Beck exerts real influence on public opinion in the US. His calls for action are answered by hundreds of thousands of people. His statements are a guidepost for millions of Americans. Aside from radio host Rush Limbaugh, no media personality in the US has such influence.
It is highly significant that thousands of Beck's supporters followed his call and came with him to Israel for a week to express their support for Israel and the Jewish people. It is similarly significant that millions more of his supporters followed his actions on Internet.
Those media that did not seek to downplay the importance of Beck's visit opted instead to distort who he is and what he is doing. As the Yediot headline indicated, the media portrayed him as an unstable messianic, or they castigated him as an extremist and marginal force in the US. Haaretz and Globes both ran articles attacking Beck as an anti-Semite.
These claims are outrageous and represent yet another gross disservice to Israeli news consumers who do not have an independent means of judging Beck, his message and his actions for themselves.
Beck came to Israel to launch a global movement of activists committed to supporting Israel, not in order to "rape" it, but in order to empower it to defeat its enemies and to stand up to an increasingly hostile world. In his speech under the Temple Mount, Beck roused his audience - which contrary to media reports was a mix of American Christians and American Jews joined by scores of Israelis - to action. With gripping prose, Beck told his audience to disregard the "convenient" lies about Israel and embrace the truth.
That truth, he said, is that "In Israel, there is more courage in one square mile than in all of Europe. In Israel, there is more courage in one Israeli soldier than in the combined and cold hearts of every bureaucrat at the United Nations. In Israel, you can find people who will stand against incredible odds, against the entire tide of global opinion, for what is right and good and true. Israel is not a perfect country. No country is perfect. But it tries, and it is courageous."
From Israel he proceeded Wednesday night to South Africa to tell the true story of Apartheid and to dispel the popular falsehood that Israel bears any similarity to Apartheid South Africa. From there he will continue on to Latin America to meet with communal leaders and mobilize them to support Israel. And from there he will return to the US where he will launch his global movement to support Israel before a mass audience in Dallas early next week.
What was most remarkable about Beck's message was its rarity. Beck did not say anything factually inaccurate. The vast majority of Israelis certainly would find nothing controversial in any of his assertions. Yet despite his honesty, and his reasonable interpretation of Israel's strategic and diplomatic circumstances, Beck's is a voice in the wilderness. One almost never comes across a foreigner - or even an Israeli - who is willing to speak such basic truths in public.
Both the rarity of truthful assessments of reality such as Beck's and the gross distortion of his message and importance by the media are the consequence of intellectual and social intimidation that has led to groupthink among members of the media and of the cultural elites in Israel and throughout much of the Western world.
As Beck put it, "The grand councils of the earth condemn Israel. Across the border, Syria slaughters its own citizens. The grand councils are silent...
"These international councils, these panels of so-called diplomats, condemn Israel not because they believe Israel needs to be corrected. They do so because it is convenient.
"Everyone does it. In some countries, it's a crime not to.
"The diplomats are afraid, and so they submit. They surrender to falsehood. The truth matters not. To the keepers of conventional wisdom, a sacrifice of the truth is a small price to pay. What difference does it make if we beat up on little Israel? These are the actions of the fearful and cowards."
And in the face of this cowardice, Beck organized his visit to Israel under the banner "Restoring Courage."
He told his audience, "I stand here to tell you this: Fear is the pathway to surrender. And to overcome fear, we must have courage."
Beck is rare, because he refuses to bow to the intellectual intimidation and groupthink that plagues the discourse on Israel in Israel itself and throughout the world. He refuses to play by the rules in which friends of Israel are castigated as messianic crazies and extremists and Israel's enemies are praised as friends and great artists and courageous dissidents. He is an exception to a demented rule.
Israel's media didn't come to their hatred of Beck on their own. Most of it is fueled by American Jewish leftists. Beck ran afoul of the liberal American Jewish establishment through his outspoken attacks on George Soros. In January, Beck ran several shows on Soros, the extremist leftist anti-American and anti-Zionist global financier who has given more than $100 million to radical leftist groups.
Among other things, Beck ran a 1998 interview that Soros gave to CBS News's Steve Kroft on 60 Minutes. During the course of the interview, Soros admitted that as a boy in Nazi occupied Hungary he collaborated with the Nazis in confiscating Jewish property. Beck dwelled on Soros's statement and his stated lack of guilt for his actions. Beck considered its impact on the shaping of Soros's personality.
For his actions, Beck was attacked as an anti- Semite by the Soros-funded Jewish Funds for Justice. The group which conducts community organizing in liberal Jewish congregations collected the signatures of several dozen rabbis and ran a $100,000 ad in The Wall Street Journal asking Fox News owner Rupert Murdoch to take action against Beck. According to JCCWatch.org, New York's UJA-Jewish Federation has given more than a million dollars to the Soros-funded organization.
The Left's attacks on Beck are fueled by the fact that he is a Christian Zionist. The Left's default mode is to accuse Christian Zionists of a hidden agenda to convert Jews and a secret desire to see us killed in an Armageddon.
But in truth the media's embrace of Israel's enemies, their rejection of Beck, and most importantly Beck's refusal to bow to their conventional wisdom that Israel's enemies should be praised and its friends should be condemned all reveal the reason that Christian Zionists can be trusted and embraced by Israelis.
Christian Zionists - like Jewish religious Zionists - are unmoved by the media's intimidation because of their faith in God, and their reliance on scripture. Their faith provides them with a means of judging reality that is independent of the largely post-religious intellectual commissariat that runs the media and the cultural elite in the Western world. They don't seek or care about receiving the accolades of the New York Times or other post-religious totems for their actions. And Beck's message to Israelis is that we shouldn't care either.
For most Israelis, this message rings powerful and true. But for the media, in Israel and throughout the West, it is dangerous sedition that must be marginalized and destroyed.
Beck said that his movement will be one of individuals who work together to defend Israel and the Jews from those who seek our destruction. He argued that regular people are far more capable of understanding what needs to be done than the well-heeled experts who lead us down the garden path of weakness and demoralization.
And he is right.And in bringing this message to Israel, he demonstrated his friendship. We should return the favor by taking his advice. We should trust ourselves and our instincts and stop listening to the "experts" who preach weakness and surrender.
Caroline B. Glick is the senior Middle East fellow at the Center for Security Policy in Washington, D.C., and the deputy managing editor of The Jerusalem Post, where this article first appeared.
Be the first to read Caroline Glick's column. Sign up today and receive Townhall.com delivered each morning to your inbox.
Rush Limbaugh defends Rubio's debate answer: He's absolutely right that Obama knows what he's doing | Allahpundit
Time for Team Hillary to break out the gender card for young liberal women who prefer Sanders | Allahpundit


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Prisoner IIby Dr. Lukas Brezak
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Last time I'll be your prisoner!
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More than 1 in 4 college women are sexually assaulted. 4% of college men report surviving assault in their lifetime. It is important to always remain vigilant, know who you are going out with, and how to get home. Take care of yourself and your friends.
There's an app for that! Connect to your friends to stay close, stay safe, and prevent violence before it happens. The Circle of 6 app for iPhone and Android makes it quick and easy to reach the six friends you choose. Need help getting home? Need an interruption? Two touches lets your circle know where you are and how they can help. For more information, and to download the app, go to Circle of 6.
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There is only one Petland store remaining in Michigan, located at Twelve Oaks Mall in Novi. Local activists from the Puppy Mill Awareness Meetup have been calling on the store to stop supporting puppy mills and start supporting rescue.
The group's peaceful demonstrations and public education campaigns have helped shut down other Petland stores in the state. The stores don't have to close -- they can choose to stop selling puppies and instead work with local rescue groups to promote adoption, as several other Petland stores around the country have done.
Support the efforts of Puppy Mill Awareness by telling Petland Novi to stop selling puppies.
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text: A video of a group of young girls, some just eight-years-old, performing a racy dance routine to Beyonce's Single Ladies has caused an internet row. The footage, filmed at America's largest urban dance competition World of Dance, shows the girls in revealing red and black lingerie outfits writhing and gyrating on stage. And while some of the girls' parents have defended the video as 'completely normal', the routine has been deemed too raunchy for dancers of that age by shocked viewers.


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"Hear ye, hear ye… Please join us for some royal fun, our Princesses are turning one!" Celebrating two sister princesses, this sister baby princesses birthday invitation is custom-colored in pretty pink and blue. Crowns, wand, and other princess graphics set the theme for your party, and you can use any of the fairytale phrases here for your own invitation. You can see more ideas & personalize this card here (simply request the pink & blue colors in the notes section, if you wish): Little Princesses Birthday Invitation.
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For the first time in forever… our princess is having a birthday party! Let your party go with this beautiful brilliant blue frost princess invitation, iced with swirling snowflakes and an optional photo. Brilliant pink and purple snowflakes accent you…


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The television starts to act strangely after being cloned too many times.
After Shake pushes him too far, Frylock moves out.
Several of the Aqua Teens' enemies join forces.
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April 17, 2015 6:26 pm
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Congress might be ready to take another stab at acquisition reform for the Defense Department. Knowing why it hasn't worked in the past could help the House and Senate Armed Services Committees finally get the job done. Bill Greenwalt is a fellow at the Marilyn Ware Center for Security Studies at the American Enterprise Institute and former deputy under secretary of Defense for industrial policy.