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This review is from: ASUS Desktop PC M11AA-US004S Pentium G2030 (3.00 GHz) 16 GB DDR3 2 TB HDD Windows 8
Pros: The PC is fast (12GB DDR) and has a large HD (2T) for pictures and videos. It was a great price from Newegg. I bought it for my wife and she loves it.
Cons: I am not a fan of Windows 8 and so installed a Classic Interface.
Other Thoughts: The first one didn't work well. After a live chat and telephone conversation with tech people at Newegg and some failed attempts to fix it Newegg sent me a new one and paid for the return of the broken one. Great service and a great company to do business with.
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Princess Projectra by StockmanArtWatch
©2012-2016 StockmanArt
One of my favourite all time legionnaires
Nice work.
this is dope, you should do a mock 3 page story of ur own in this style as a pitch. i hate legion but id buy this
you lost me with "i hate legion"....for shame...
Beautiful rendering. You should be the one drawing LSH!

subset: commoncrawl


text:
Sebastien Loeb: "Winning is always nice, but today's victory has a special taste to it because it's our first since last April!"
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Human rights
IHG supports and protects human rights wherever it can. As a responsible company with operations in 100 countries and territories, we believe strong ethics and good business go hand in hand. We're committed to complying with the laws and regulations of all the countries and jurisdictions in which we operate and our human-rights policy is available in 42 languages. All our policies can be found here.
To demonstrate our commitment we:
- support the protection of human rights, particularly those of our colleagues, the parties we do business with and the communities where we operate
- respect our colleagues rights to voluntary freedom of association under the law
- provide a safe and healthy working environment
- do not support forced and compulsory labour or the exploitation of children
- support the elimination of employment discrimination and promote diversity in the workplace
- provide our colleagues with remuneration and tools for growing their careers, and take their well-being into consideration
- promote fair competition and do not support corruption
- conduct our business with honesty and integrity in compliance with applicable laws
- develop and implement company procedures and processes to ensure we comply with this policy.
We focus on areas of human rights most relevant to our business ensuring the rights of the local people where we operate are protected. We are working to raise further awareness of our human rights approach in our hotels through embedding our standard and will continue to develop our training materials. We are a signatory to the UN Global Compact aligning our operations and strategies with the 10 universal principles that include commitments to human rights and labour standards. We are part of the Business in the Community cross industry working group on human rights as well as the International Tourism Partnership's Human Trafficking Working Group. We are also working with our internal procurement team to embed further our human rights approach into our contracts.
In 2014, we established a standard which requires all IHG hotels to adopt and display a Human Rights Policy at individual property level. This new standard builds on our work in this area and demonstrates our ongoing commitment to operating as a responsible business.
Our employees
Having a predominantly managed and franchised estate means that not all of the people who work at our hotels are our employees. When the Group's entire estate is taken into account (including those working in our franchised and managed hotels) over 350,000 people worked globally across IHG's brands as at 31 December 2014. However, IHG employed the following:
- 7,797 people worldwide (including those in our corporate offices, central reservations offices and owned hotels (excluding those in a category below)), whose costs were borne by the Group
- 4,975 people who worked directly on behalf of the System Fund and whose costs are borne by the System Fund
- 602 General Managers who work in our managed hotels and whose costs are borne by those hotels
- 11,848 other hotel workers who work in our managed hotels who have contracts or letters of service with IHG and whose costs are borne by those hotels.


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Thats Casey
2007 Ducati - great,excelent year
2008 Ducati - worse then previous year
2009 Ducati - worse then previous year
2010 Ducati - worse then previous year
2011 Honda - great year
2012 Honda - worse then previous year


text:
Top Definition
Younger man who has smaller income and assets than a "Sugar Daddy". Usually much better looking but may have less money.
Female: "Dam, my sugar daddy has old balls, I need a sugar packet daddy."
by silverround July 17, 2008
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Winter Morning by NebrideWatch
©2012-2016 Nebride
I was with my grandparents this Christmas, and they live in a very secluded house out in the woods, more or less. Woke up to a gorgeous sunrise one morning and I had to get this on (my new!) camera I' not much of a photographer, but I hope you like it anyway
I hope all of you had a wonderful Christmas!
I hope all of you had a wonderful Christmas!
I love my country.
Wow! So pretty! And you're fucking good at taking pictures, it's gorgeus!
"I'm not much of a photographer" - yes, you are. now go out and take more photos of this beautiful country
Haha, my other interests take up a lot of my time, and I've never known much about photography, but I'm sure that won't stop me from snapping a shot whenever I have the opportunity Thank you for the comment!
A real winter wonderland, so atmospheric for Christmas!
beautiful shot!
Amazing !
How beautyful
Hvor i norge er det?
Hvor i norge er det?
Woow.. So amazing♥ Where is it ? Must be such a wonderful place.
Thank you! This is in Norway, very far South in the country Definitely one of my favorite places to visit!


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Southport hotels
Southport, the commercial centre for Gold Coast City, is home to most of the major businesses and shopping centres in this area. Many visitors are interested in the beautiful beaches of nearby Surfers Paradise, but one can enjoy plenty of water sports from the marinas on Broadwater and Nerang River. There are also scenic waterfront walkways following the pedestrians and cyclists and fishing piers. Whilst Southport is not a heavy tourist area, it is certainly tourist-friendly, with plenty of shopping, dining, and nightlife options for visitors to enjoy in a more relaxed, less crowded atmosphere.
- Watch birds and other wildlife, or go on a hike, or have a picnic, or enjoy open-air concerts or films or any of the Gold Coast annual festivities at the Southport Broadwater Parklands.
- Shop for fashion, jewellery, and liquor, or enjoy beauty treatments or massages, and have a bite to eat or watch a film at the Gold Coast Australia Fair, a giant shopping mall and entertainment complex.
- Enjoy exhilarating water rides, view huge aquarium exhibits, and watch Shamu and his aquatic friends perform at Southport Sea World.
Coolangatta Airport is 26 kilometres from Southport via the Gold Coast Highway, and airport transportation options include vehicles for hire and a shuttle bus. This is a small airport, so you may want to fly into Brisbane and hire a car or take the train to your final destination. Getting around by car is very easy, and parking is not hard to find. Some areas have metered parking, but you can find parking garages and lots that are cheaper. Southport has a public bus service as well, and it is a pedestrian and bike-friendly area.
Recommended hotels
1 Aquarius Backpackers Gold Coast Hostel
44 Queen Street Map
Travellers will find suitable accommodations in an ideal location at the Aquarius Backpackers Gold Coast Hostel. With its close proximity to shopping, entertainment and dining options as well as... More
2 Ashmore Palms Holiday Village
71 Hinde Street Map
Includes FREE Onsite Parking
Ashmore Palms Holiday Village Resort is a popular resort style accommodation choice for families, couples and groups residing on Australia's beautiful Gold Coast, offering guests a range of quality... More
3 Arrival Accommodation Centre Hostel Gold Coast
69 Queen Street Map
Arrival Accommodation Centre Hostel Gold Coast is a contemporary budget-friendly property suitable for vacationers looking for homey accommodations and convenient access to Surfers Paradise in Gold... More
school holidays
Refine your search
- Seabreeze Sports hotels
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- Sea World hotels
- King Tutts Putt Putt hotels
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- Riples Believe It Or Not! Museum hotels
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- Wax Museum hotels


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Cyclists to Ride "Tour De Paris" In Bourbon County October 19th
By Matt Kelley • Oct 3, 2013
The residents of Bourbon County Kentucky will be hosting the "Tour De Paris" bicycle event in just a few weeks. The ride doesn't take place in France, but organizers say it may be just as scenic. Spokesperson Elisha Bowman told WNKU's Matt Kelley that they hope the play on words will bring out more cyclists to enjoy the fall weather.(get details at www.parisky.com.)


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Thanks for taking the photo of the Relyea family for me.
Added by
on Mar 26, 2012 5:00 PM
Marian Corya
Katie Weikel
Thank you for the photos of Katie Weikel and baby John Weikel. I did not know about John, so have edited the bio to reflect his birth and brief life.
Added by
Marian Corya
on Jun 13, 2011 4:38 PM
Gail Radtke
Anna Mildred Howe Radtke
Mount View Cemetery has two more Find a Grave residents because you documented Mildred & Carl's headstone photograph on their new memorials sites. We appreciate your help. May God Bless you.
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Gail Radtke
on Apr 14, 2011 11:43 AM
Thys DeYoung
RE: William Lodewyk
Thank you so very, very much. My cousin is thrilled with the picture you took of William's grave!!
Added by
Thys DeYoung
on Apr 13, 2011 1:17 PM
Thys DeYoung
William Lodewyk
Thank you so much for the picture of the headstone of William and Adriana Lodewyk. My cousin in Friesland will be so happy. If you know of or have time for other Lodewyk family photos, I would greatly appreciate it!!
Thank you again,
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on Apr 13, 2011 11:05 AM
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Carl F. Radtke
I know that Spring is trying to come to Michigan and this means that great volunteers like you are able to find our ancestors now that the snow and storms have receded. By taking this picture you have verified Carl and his wife Anne Mildred Howe are buried side by side, which means I will soon be requesting that you add Carl's picture to Mildred's find a grave memorial site. Welcome and thank you for volunteering.
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Twitter unveils self-service advertising system
(AP) -- Buying ads on Twitter is about to get easier for small businesses as the online messaging service adds a key piece to its moneymaking model.
(AP) -- Buying ads on Twitter is about to get easier for small businesses as the online messaging service adds a key piece to its moneymaking model.
Within just over a week, Netflix and Hulu are both debuting their first stabs at original scripted programming.
Cable television is the leading source of US political news for Americans, according to a study released Tuesday, but fewer people are closely following the presidential campaign than four years ago.
Aneesh Chopra, who was tasked with bringing a dose of Silicon Valley to the US government as the first chief technology officer, is stepping down.
The Philippines has launched a new campaign promoting tobacco -- not for smoking but for fish farming, a government tobacco agency official said Thursday.
Google Inc., under scrutiny from privacy watchdogs for changes it made to its search engine, is launching a splashy ad campaign designed to alleviate privacy concerns.
Cyber-environmentalists said Thursday they aim to mobilise millions of people around the world for a mass waste clean-up, saying they had to step in because governments had failed to do so.
(AP) -- Intel Corp. says it is betting big on its "ultrabook" concept with its largest advertising campaign since 2003.
South Korea has tightened monitoring of popular social networking sites to curb illicit content including an upsurge in North Korean propaganda, officials said Thursday.
Filipino entrepreneur Illac Diaz is aiming to help a million poor people in a year, and with the help of some plastic bottles and a clever social media campaign may do even better.


text:
Feel free at Audiko, where you can use hot ringtones for your mobile phone. Today we have a ringtone of "Для тебя" by Звери as well as 641 other ringtones by Звери. "Для тебя" is a gorgeous track from the "Голод" album that was composed by Звери at their label together with other 18 tracks. You can listen to all 4 Звери – "Для тебя" ringtone variations available here and download it for free right here. You can also take a glance at other 7 albums produced by Звери for all time. "Для тебя" is referred to Russian, and we have a huge amount of Russian songs absolutely for free. And finally, we have collected lyrics for this track and you can view it here as well. So feel free to browse, listen, download ringtones at Audiko.net. Make your phone sound cool!
Звери Для тебя Ringtone
Similar Ringtones
Browse Genres
Pop Pop Rock Pop-Rock Rock Russia Russian Russian rock
Albums by Звери
Top ringtones by Звери
New ringtones
- CURB - Curbyourenthusisam
- Chicago - Hard to Say I'm Sorry (Single Version)
- Jose Luis Rodríguez - Si tu me dices ven
- Armand Van Helden feat. Duane Harden - U Don't Know Me
- Carla's dream - sub pile mea
- silencium theme from the silent witness - silencium theme from the silent witness
- Pepe El Marismeño & Diego Carrasco - El Feo
- 手机铃声之家 - [unknown]
- Unknown - Jason derulo - Get ugly Lyrics
- Major Lazer - Thunder & Lightning


text:
Definitions for evenhandedly
This page provides all possible meanings and translations of the word evenhandedly
Princeton's WordNet
fairly, fair, evenhandedly(adverb)
without favoring one party, in a fair evenhanded manner
"deal fairly with one another"
In an evenhanded manner.
Translations for evenhandedly
From our Multilingual Translation Dictionary
- tasapuolisestiFinnish
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text:
Just off the heels of CES, Sony throws in another little surprise announcement for us including new CPU options and enhancements plus new color options on various laptops. The Sony Store team is also giving away a free gift with purchase of a C series laptop in celebration of some new designs. Details are below […]Read More
It's not just new winter coats you're seeing this fall hit store shelves. Today, the Sony VAIO® division has released a variety of updated models in preparation of this holiday season. Available today on SonyStyle.com, this fall's update reveals not only new CPU options but a few other enhancements. Here's the latest and greatest to […]Read More


text:
Showbiz Daily 'Variety' Sold To Penske Media
Penske Media bought the 107-year-old magazine for $25 million. Unlike its longtime competitor, The Hollywood Reporter, Variety has had trouble making the switch to digital media.
And staying here in California, our last word in business is lights, camera, sold.
The sale of Variety is officially a wrap. The venerable 107-year-old show biz daily has been bought for $25 million by Penske Media, the owner of Variety's upstart online rival Deadline.com. Like its longtime competitor, the Hollywood Reporter, Variety has had trouble making the switch to digital media, but it still turns a profit. So in the language that Variety helped make famous, Penske seems to believe this deal will be boffo and not a flopola.
And that's the business news on MORNING EDITION from NPR News. I'm Renee Montagne.
MONTAGNE: That's a word. They used it. They use it...
MONTAGNE: ...every day on the front page.
INSKEEP: All right. I'm Steve Inskeepo.
Copyright © 2012 NPR. All rights reserved. Visit our website terms of use and permissions pages at www.npr.org for further information.
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Working parents of crap sleepers. How do you do it???(62 Posts)
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Does anyone know how to use Java for Strong code mobility? Have you ever done it before?
Here's what I try to achieve.
Suppose we have 2 separate Java applications that communicate over network. App A and App B.
App A has a class x instantiated as an object, and has been using it. App B has no prior knowledge of this class x.
App A needs to migrate the instance of class x over to App B. App B should be able to dynamically load class x, and retains the state of class x.
I have Googled around and found a bunch of resources on how to dynamically load class at run-time. However, I'm not sure if the mechanism of transferring an object instance over network along with its state, and to invoke it dynamically is covered.
Any pointers would be very helpful, and thank you in advance!
NOTE: I'm mostly interested in how (i.e. the approach, way to think) this problem is solved, not what is used to solve this; this is because I'm tasked to come up with my own solution to solve this problem. Though pointing out libraries/framework is great, it would be ideal if answers are posted from people who have done something like this before (however rare).


text:
Welcome to Smogon! Check out the Smogon Info Hub for everything you need to know about starting out in the community. Don't forget to introduce yourself in the Introduction Thread, too!
Welcome to Smogon Forums! Please take a minute to read the rules.
The Social Media forum has returned from the grave!
Ever find yourself missing out on the latest Smogon articles? We've now got a subscription service, so the newest articles (of your choice) are delivered right to your inbox! Check it out here.
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Male, from Arizona
If you're going to start pointless drama with me, you better bring your big guns. I won't hold back if you try to start shit for no reason. Sep 23, 2015
- nightwolf was last seen:
- Feb 14, 2016 at 12:11 AM
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Signature"You really do remember me this time? I'm SO FLATTERED...But you're too late!!"
- Axel to Roxas in Kingdom Hearts II
"Let's see, here... "If the subject fails to respond, use aggression to liberate his true disposition"... Right. Did they ever pick the wrong guy for this one..."
Y'know how people complain about people bringing guns to knife fights? Well, I'm the guy that brings the nuke to that same fight.
- Gender:
- Male
- Location:
- Arizona
- Real Name:
- James
- Favorite Pokémon:
- Latios
- My Characteristic:
- Likes to relax
- 3DS Friend Code:
- 1864 9792 3318
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text: florida 1/7/15 Panel By Joe Donahue • Jan 7, 2015 Listen Listening... / 41:48 The Roundtable Panel: a daily open discussion of issues in the news and beyond. Today's panelists are WAMC's Alan Chartock, political consultant Libby Post, and WAMC newsman, Ray Graf. Topics include: Shootings in France at the offices of Charlie Hebdo and in El Paso at the Veterans Affairs Health Care System's clinic, Gay Marriage in Florida, Robert F. McDonnell sentenced to two years in prison, Boehner beats dissent. The Book Show #1376 - Carl Hiaasen By Joe Donahue • Dec 2, 2014 Listen Listening... / Carl Hiaasen writes a regular column for the Miami Herald and is the author of many bestselling novels including Star Island and Bad Monkey for adults and Hoot, Chomp, Scat, and Flush for young readers. His latest, Skink - No Surrender is his first novel for teens. 'No Land's Man' By Aasif Mandvi By Joe Donahue • Nov 5, 2014 Listen Listening... / 20:34 If you're an Indo-Muslim-British-American actor who has spent more time in bars than mosques over the past few decades, turns out it's a little tough to explain who you are or where you are from. In No Land's Man, Aasif Mandvi explores this and other conundrums through stories about his family, ambition, desire, and culture that range from dealing with his brunch-obsessed father, to being a high-school-age Michael Jackson impersonator, to joining a Bible study group in order to seduce a nice Christian girl, to improbably becoming America's favorite Muslim/Indian/Arab/Brown/Doctor correspondent on The Daily Show with Jon Stewart. Vox Pop : Open Forum - The Acquittal Of George Zimmerman : 7/16/13 Flickr/Ann Harkness Across the country, communities are continuing to react to Saturday's acquittal of Sanford, Florida neighborhood watch volunteer George Zimmerman for the killing of 17-year-old Trayvon Martin. On Sunday, the U.S. Justice Department said it is reviewing evidence in the case to determine whether federal criminal civil rights charges are warranted. Today we want to hear your take on the verdict and whether George Zimmerman should face charges of racially motivated criminality. WAMC's Alan Chartock hosts. Congressional Corner with Rich Clark - Part 3 By David Guistina • Mar 28, 2013 Listen Listening... / 8:53 The 2016 parlor games have already begun. In today's Congressional Corner, Rich Clark, Associate Professor of Political Science and director of the Castleton Polling Institute, tells WAMC's David Guistina that Florida will remain important in the next election . The Book Show #1283 - Dave Barry By Joe Donahue • Feb 19, 2013 Listen Listening... / 25:00 Insane City is Pulitzer Prize winning humorist Dave Barry's first novel in more than 10 years, though he has been writing non-fiction best-sellers during that time. In the book, Seth Weinstein is on his way to his destination wedding in Florida. Little does he know what's in store: Russian gangsters, angry strippers, a desperate Haitian refugee and her two children on the run from some very bad men, and an 11-foot albino Burmese python named Blossom.


text:
You limited your search to:
Year: 1866
Month: June
Day: 30th
Collection: Union (German, Galveston)
Die Union (Galveston, Tex.), Vol. 8, No. 106, Ed. 1 Saturday, June 30, 1866
Date: June 30, 1866
Creator: unknown
Description: Tri-weekly German newspaper from Galveston, Texas that includes local, state and national news along with advertising.
Contributing Partner: The Dolph Briscoe Center for American History


text:
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Amy-Mae Elliott
Occupation: Writer (Mashable.com)
Location: Devon
Her ProfilesRankThis is the rank of 'Amy-Mae Elliott' out of all Google+ Profiles (individuals).: 8,867 (GenderRankFor the gender 'Women'.: 5,001)
Her ProfilesRankThis is the rank of 'Amy-Mae Elliott' out of all Google+ Profiles (individuals). in Canada: 138 (GenderRankFor the gender 'Women'.: 49)
Her CircleRankThis is the rank of 'Amy-Mae Elliott' out of all indexed profiles (individuals) and pages (businesses) at CircleCount.com.: 17,928
Her CircleRankThis is the rank of 'Amy-Mae Elliott' out of all indexed profiles (individuals) and pages (businesses) at CircleCount.com. in Canada: 152
Followers: 27,167
Following: 50
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Top posts in the last 50 posts
Most comments: 27
2011-07-26 12:47:44 (27 comments; 0 reshares; 5 +1s)
Hi again!
So, last crowd-sourcing (or should that be plus-sourcing?) from me today - I promise!
What interesting uses of G+ hangouts have you seen so far?
I have seen concerts, cookery lessons, a press conference and a couple more, but I'm looking for the most awesome and innovative examples for a Mashable article.
If you've come across something relevant, please share it in the comments!
Most reshares: 25
Most plusones: 36
Latest 50 posts
2013-04-09 16:05:20 (2 comments; 1 reshares; 10 +1s)
It's that time of year!
2012-06-27 14:55:48 (3 comments; 4 reshares; 16 +1s)
I pulled together some handy tips for anyone who uses Skype as an IM tool. Let me know any of your hints in the comments!
2012-05-16 11:25:00 (2 comments; 0 reshares; 12 +1s)
So, does anyone on here DO THE ROBOT???!?!? :)
2012-05-10 14:50:33 (0 comments; 2 reshares; 9 +1s)
I check out Viddy for Mashable.com. Share any cool clips you've created in the comments!
2012-04-19 19:06:37 (2 comments; 2 reshares; 11 +1s)
Mashable's community manager +Meghan Peters talks G+!
2012-03-30 15:55:18 (3 comments; 3 reshares; 11 +1s)
Beware! :D
2012-03-28 16:38:44 (1 comments; 2 reshares; 8 +1s)
Bringing paper back! :)
2012-03-26 10:35:48 (0 comments; 2 reshares; 6 +1s)
Invasion of the kitties!
2012-03-12 16:31:07 (1 comments; 0 reshares; 9 +1s)
This was a fun one to research and write - it's basically window-shopping!
2012-03-07 14:29:16 (1 comments; 7 reshares; 8 +1s)
"Don't read beauty magazines, they will only make you feel ugly..."
2012-03-01 19:51:30 (4 comments; 7 reshares; 12 +1s)
If you're really clever, +InMotion Hosting offers a tutorial on animating your Google+ profile.
If you're quite very clever +Giles Pettipher offers his methodology.
If you're like me, then I'm offering a really simple way of getting your profile moving!
2012-02-21 16:18:36 (10 comments; 7 reshares; 11 +1s)
If you have a spare five mins, take a look through this fun gallery of animated G+ profiles, featuring +Dunken K Bliths +Eric Cheng +Ralph Roberts +Daria Musk +Anthony Widdowson +Trey Ratcliff +Evo Terra +Jeremy Cupp +Adam Simmons +Giles Pettipher - they're awesome!
2012-02-20 18:11:32 (0 comments; 2 reshares; 7 +1s)
GifBoom is a useful mobile tool if you're a fan of animated images.
2012-02-17 17:32:32 (1 comments; 3 reshares; 4 +1s)
You can now share TED Quotes to Facebook and Twitter. No native G+ option, but still cool!
2012-02-16 19:04:05 (2 comments; 3 reshares; 5 +1s)
This is a fun Pinterest "hack". Make montages out of your boards...
2012-02-15 20:16:46 (2 comments; 0 reshares; 6 +1s)
What is it that you really do? I'm convinced my old-fashioned parents don't really think I have a "proper" job, so aspects of this meme really made me smile.
2012-02-14 14:07:58 (2 comments; 4 reshares; 7 +1s)
G+ Valentine's cards from +Aaron Wood - awesome!
2012-02-14 14:06:01 (9 comments; 0 reshares; 1 +1s)
I'm looking for awesome animated Google+ profiles to showcase on Mashable.com.
If you have one, or have seen one, then please link me in the comments!
2012-02-14 12:32:07 (2 comments; 1 reshares; 4 +1s)
Cute! Happy V-Day!
2012-02-13 18:55:58 (2 comments; 6 reshares; 8 +1s)
I wish I could make videos like this! So clever and really effective, especially when the lyrics are good.
2012-02-08 16:31:44 (1 comments; 0 reshares; 3 +1s)
Are you going to be sending a geeky V-day card? These cards I curated from what's currently on offer over at Etsy are just marvellous!
2012-02-07 16:28:53 (4 comments; 0 reshares; 8 +1s)
Cute! Have an 8-bit Valentine's!
2012-02-06 14:33:13 (0 comments; 3 reshares; 4 +1s)
This was fun to write! These apps make creating stop motion videos very easy.
2012-02-03 17:55:04 (1 comments; 5 reshares; 10 +1s)
2012-02-02 19:10:19 (0 comments; 3 reshares; 2 +1s)
Here's some hints to get the most out of iPhone Voice Control.
2012-01-30 19:56:14 (2 comments; 5 reshares; 9 +1s)
Any dog-lovers out there? This is gorgeous!
2012-01-27 16:40:43 (2 comments; 1 reshares; 4 +1s)
These need to stop now. Agree or disagree?
2012-01-26 14:35:23 (0 comments; 6 reshares; 12 +1s)
If you use Google Calendar, then I hope these tips and tricks help!
2012-01-25 16:07:37 (6 comments; 4 reshares; 1 +1s)
Here's how to tweak Facebook to your liking... Go retro!
2012-01-17 16:22:15 (0 comments; 0 reshares; 3 +1s)
This was fun to write. If you've got any good ones then add them in the comments - I'm looking to do another gallery from reader submissions!
2011-10-04 13:53:16 (0 comments; 3 reshares; 7 +1s)
Ahead of the iPhone 5 launch I've taken a look back at old Apple media event invites... There's clearly a lot of time and effort that goes into the design of them, but whether they provide any real clues is debatable...
2011-09-27 11:17:38 (3 comments; 4 reshares; 22 +1s)
Happy 13th birthday to Google!
2011-09-13 19:12:39 (3 comments; 0 reshares; 6 +1s)
More cowbell!
2011-09-09 17:39:17 (8 comments; 0 reshares; 9 +1s)
I'm guessing these might go down well on here... ;)
2011-08-25 14:44:44 (3 comments; 5 reshares; 14 +1s)
September is incoming... I still get that back-to-school feeling even though I've been out of Uni for years!
2011-08-08 14:29:22 (1 comments; 5 reshares; 9 +1s)
Any iPhotographers out there? :)
2011-08-05 12:42:31 (8 comments; 20 reshares; 14 +1s)
My latest G+-themed article - how to easily record a Hangout. What tools do you use?
2011-08-03 12:42:39 (8 comments; 4 reshares; 17 +1s)
This was a fun one to write and research! Enjoy :)
2011-07-29 18:57:00 (10 comments; 21 reshares; 23 +1s)
Last (work) post from me this week - I took a look at some third party Google+ sites and services for Mashable.com.
If there's any that didn't make the cut that you recommend then please shout 'em out in the comments.
(Thanks to Mash features intern +Stephanie Buck for contributing to the research, circle her if you haven't already -- she's lovely!)
2011-07-28 16:45:30 (21 comments; 16 reshares; 14 +1s)
Here are four fun ways your fellow Plussers are using G+ Hangouts.
Thanks to +Mary Robinette Kowal, +Daria Musk, +Rob Michael, +Mark Olsen & +Lee Allison for taking the time to provide me with info about their great projects.
I will be following this up with a more serious look at business uses of Hangouts, so please get in touch if you're doing something innovative!
2011-07-27 16:50:54 (5 comments; 3 reshares; 22 +1s)
Congrats to +Pete Cashmore and the rest of the Mashable crew as we hit six! To mark the anniversary, here's a nifty infographic showing how the social media industry has grown over the last six years. It's astonishing how much has changed.
2011-07-26 12:47:44 (27 comments; 0 reshares; 5 +1s)
Hi again!
So, last crowd-sourcing (or should that be plus-sourcing?) from me today - I promise!
What interesting uses of G+ hangouts have you seen so far?
I have seen concerts, cookery lessons, a press conference and a couple more, but I'm looking for the most awesome and innovative examples for a Mashable article.
If you've come across something relevant, please share it in the comments!
2011-07-26 12:24:17 (7 comments; 13 reshares; 16 +1s)
Here's five more tried-and-tested Google Chrome extensions I wrote about for Mashable.
I wonder how much of this functionality Google will eventually make native? For example, I expect the in-site search to ramp up soon.
2011-07-21 21:38:37 (0 comments; 0 reshares; 4 +1s)
An update from Mashable News. Feel free petition Pete for more cat pics! I will be... ;)
2011-07-21 18:40:21 (6 comments; 13 reshares; 24 +1s)
Cool beans! Here's a template to help you "hack" your G+ profile.
2011-07-21 16:02:07 (11 comments; 8 reshares; 19 +1s)
I was inspired by +Brian Rose's excellent G+ profile hack to round up some great examples into a gallery. I will be adding to it, so if you've got creative with your profile let me know!
2011-07-20 19:12:41 (10 comments; 1 reshares; 3 +1s)
NOOOOOOOOO! This makes me very sad :(
2011-07-19 20:53:56 (4 comments; 7 reshares; 21 +1s)
I love The Oatmeal. Here's a lame "circles" joke... ;)
2011-07-19 15:49:04 (14 comments; 6 reshares; 14 +1s)
Google+ for iPhone!
A special service of CircleCount.com is the following button.
The button shows the number of followers you have directly on a small button. You can add this button to your website, like the +1-Button of Google or the Like-Button of Facebook.
You can add this button directly in your website. For more information about the CircleCount Buttons and the description how to add them to another page click here.


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DrugTest 5000 - Draeger Safety Diagnostics Inc
In the past, roadside drug screening has been difficult because it involved the...
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A memorandum of understanding signed by Attorney General Alberto Gonzales and Canadian Minister of Public Safety Stockwell Day marks the first in which the United States has agreed to immediate sharing of crime-scene information with a foreign government.
Click here to read the entire article.
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The film's soundtrack will also feature an unreleased 12-minute acoustic song by Cobain
Grunge is so ingrained in fashion's psyche today that it's difficult to imagine it was born with the style of one person. As Nirvana's front man, Kurt Cobain brought not only angst (and empathy and solidarity) to a nation of disaffected youth, he also brought it his shabby, old-folks-gone-to-seed look. Never has so noble a revolution come clad in so baggy a cardigan.
Photography by Greg Broom


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Do you guys agree with Charlie or disagree??
CBS (ended 2015)
Do you guys agree with Charlie or disagree??
|numberone1991 wrote:
|i disagree because its still funny.
I don't think I've laughed once yet this season.
It should be axed or bring Charlie back = AXED!!
It's sad and they should bring Charlie back from the dead.
|Pieter79 wrote:
|Agree! The pilot was a bit funny, but the rest is mediocre.
It's like watching Joey because you liked Friends.
Well, I also liked Joey, but it wasn't Friends. That was the comparison I wanted to make. The old Two and a Half Men and te version with Kutcher is the same big difference.
Nothing against Holden McGroin!
|Pieter79 wrote:
Well, I also liked Joey, but it wasn't Friends. That was the comparison I wanted to make. The old Two and a Half Men and te version with Kutcher is the same big difference.
Nothing against Holden McGroin!
I kinda agree, because it sucks. I don't agree because it was clear it was gonna suck from the second they hired Asston, so it lives up to my expectations.
Kudos though forwhoever typecastedhim asa pathetic whining baby moron.
|hell693 wrote:
|I agree with you, people should think of it as a new show and not the show that sheen starred in.
That's a load of crap. If they wanted it to beseen as a new show they should have presented it as a new show, and not keep the title, the cast, the theme tune. Now they are just cashing in on Sheen's reputation and all the controversy, and it won't pay off in the long (or even medium) run.
I think is really sad that they pay 1 million for episode to Ashton Kutcher for this atrocity. He doesnt deserve it, the only thing ok with his carrer is thats 70 show, aside from that he sucked in everyhting he did. Such an overrated actor, meanwhile great tv actors like Dominic West or Mark Valley fly under the radar
It is getting funnier after each episode.
Give it time people, change is difficult.
We still have Alan, Jake, Berta and Herb!
This is unfair!
I'm not sure I like the direction they're going with Jake, turning him from lovable dunderhead to burnout dopehead...and Alan's on-again-off-again relationship with Lindsay MacElroy is becoming tiresome. Though, I do like the attempts to provide arcing storylines and continuity between episodes (e.g. Alan temporarily committed, the question of Millie Melnick's parentage brought up a couple of times, Rose's return, Walden's spurned ex and cold fish of a mother teaming up to grab his company). They have to be leading up to something big for the season/series finale. Maybe Charlie Sheen will put aside his differences with the producers and do a cameo as the Ghost of Charlie the Man-Whore or something.


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I've been searching for some thanaz in 8sv but when I finally tried them I didn't like the cut. So I looked on the Diesel online store and saw that they had Viker in 8SV and on sale in my size! Can't wait to get them! Those will be my F off jeans! lol
Trending on Denim Blog:
I bought a pair from a member on this forum and LOVE them. I think you'll be very happy with them when they arrive.
Awesome! Have any pics of you wearing them?!
- 3 Posts. Joined 4/2010
- Select All Posts By This User
Where did you find them on the Diesel online store? Could you post the link?
Yes they are on the offical Diesel online store! Here's the link!
- 14 Posts. Joined 2/2010
- Location: USA
- Select All Posts By This User
Nice! Congrats, post pic when u get them!
Unfortunately, I'm without camera at the moment. The camera on my phone sucks, but I'll try and get a pic with them when I wear them out, tomorrow night.
Thanks Kazakh and I will! That sucks karnodal
Here's me in the Vikers. I love the wash and they are so comfortable but I should have sized down. Damnit oh well these are my f off jeans anyway so lol
Dear Viker lover(lol),
so nice wash and back pocket design...
i never seen before this back pocket design on VIKER.
plz post pics to WDYWD too...
as viker fit, so nice
that means even though u know safado cut, u select viker
this fit is so nice IMO.
from looks around the your ankle, i recommend u safado too.
so, i like viker. u know well..
my viker-73J
safado-8IW(will ship to germany)
Edited by sand_dolphin2 - 7/17/10 at 4:38am


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omari granberryTwitter Stats
@TherealOmarion - Tracking since July 4, 2011
singer,actor,dancer,songwriter,movie producer.
los Angeles, california
omari granberry Tweets
@TherealOmarion has posted 0 tweets in the last 30 days, which translates to an average of 0.0 tweets per day.
omari granberry Followers
@TherealOmarion has 21 followers.
This account is #96,714,100 in the worldwide rank of the most popular Twitter users.
omari granberry Following
@TherealOmarion is following 3 Twitter accounts.
Last month this account followed no users.
omari granberry Predictions & Milestones
@TherealOmarion will hit 21 followers in the next 3 months, and 21 in one year.
You are on omari granberry's Twitter stats page
We track these Twitter stats since July 4, 2011 . You can see how many followers omari granberry lost or gained and what the prediction is for tomorrow or the next 15 days, together with all kinds of other stats like rank compared to all Twitter users, tweets etc.
Why don't you give it a try and compare omari granberry to yourself ? Or if you are omari granberry get even more feature rich & up-to-date stats with Premium & Pro Twitter Stats.
Twitter Counter is the #1 Twitter stats site powered by Twitter. It all started in June 12, 2008 and we grew rather rapidly because of our Twitter Counter badge. The button is a nice small image that shows your visitors how many followers you have on Twitter. Within a year the button was on many many blogs around the world and we displayed more than 100 million buttons in one month. We track follower stats for over 180 million users now.


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Bill Maher bashes stay at home moms
View Single Post
The Postmaster General
King of all Schmoes
Join Date: Jun 2002
Location: Your local zip
Posts: 23,855
Favorite Movie: Back to the Future
They Ann Romney criticism didn't come out of the blue. It was a response to her comparing herself to stay at home moms everywhere, when everyone knows darn well that her situation is mostly incomparable.
What I do think is ridiculous is what's been said - It boggles me that stay-at-home moms are the new subjects for political correct speech. I think it's just so out of the blue because the current debate seems to be ignoring decades of socially accepted progressions in equal rights for women. The feminist manifesto in the 70s sent women to work and said they needed to break away from that housewife persona, and we all accepted this for a long time, and suddenly out of nowhere, staying home and raising kids is the same thing as working for the man. Sorry, no -- we've clearly established that wife's role isn't to solely work for the man (in this case being the husband/breadwinner). Isn't that what makes women equal?
And yes --- Being a mom IS a "job", but this whole thing has turned into semantics on what we call a job and it's just a bunch of political bullshit. Everyone knows what the other person means but is to proud to acknowledge it. No one was bashing Ann Romney for being a stay at home mom, they were bashing her for comparing her situation to that of 99% of working moms. There is hardly a comparison there and she was an idiot for trying to make one -- for trying to be "down" with all the regular moms. It was pandering at its worst, and even worse because she's not even the candidate.
Last edited by The Postmaster General; 04-19-2012 at
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text:
Team Associated Steering Block Set (Hard)
This is an optional Team Associated Steering Block Set, in Hard compound.
This product was added to our catalog on February 18, 2008.
Customers that bought this also purchased...
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- Details
Ansell Marigold™ G25 Gloves
- Nitrile-coated gloves provide excellent resistance to solvents and oil-based chemicals
- Dependable hand protection from cuts, snags, punctures, and abrasions
- Silicone-free to prevent product contamination
- Nitrile gloves are compliant with the regulations set by 21 CFR and CFIA for foor applications
- Available in green and blue
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Apr 9
Aug 16
more info TBA
Jun 29
benefit show, more info and full lineup coming soon
Jun 12
more info tba
Apr 19
Sounds Like: Silkworm, Guided By Voices, Built to Spill, Neil Young, Nirvana
Label: 75orLess Records
Manager: Patrick McT @ Cheese Fox Booking
Currently booking shows for FALL '13
Providence/Boston/PortlandME/NYC/Western Mass/Worcester/Albany/etc.
email firstname.lastname@example.com
or email us directly @ email@example.com
OFFICIAL BAND BIO (updated 3/22/2012)
Broadcaster has been active since fall of 2009 when George McTernan a...See Full Bio
"Guitarist and vocalist Chris McTernan has been steering Broadcaster since the days when they hailed from Worcester and were called Killing Pablo. From that band's even noisier and more lo-fi template emerged a beautifully damaged sound that's brimming with soaring guitar lines and choked with equal parts tremelo and rage. Broadcaster's confessional, pop art songwriting seems heavily influenced by Silkworm and Gang of Four."


text:
nice :P
This mod adds new units to all sides along with a new soundtrack with more to be done in the future. This mods previous name was Battlefield 1945-2012 and changed to something more suiting and well a better appealing name.
nice :P
Needs texture.
my eyes!
nice,but,needs texture
Here's some pics of the new navy to balance/ replace


text:
DELIVERY ALERTS: The South African Post Office (SAPO) is experiencing longer than usual delivery delays as a result of the recent postal strike.
I don't have to order nuskin product every month now! Just 3 times a year from rankines. I am saving probably a $1000 dollars or more. Thank you.
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K. BRANNIGAN, message dated 6/25/2014 4:03:35 P.M. Eastern Daylight Time
Received the SG2PRO. It's simply lovely. Also find the Gelee to be exceptional - re: firming gel. Cheers.
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My goal is to use your products that were highly recommended by a friend. I usually buy nut-skin products but they are very expensive. I hope your products can do the same job as nut-skin. I can wait to try them!!…
Adriana from Lachine, QC, message dated Tue, April 14, 2015 4:01 pm PST
Dear Dr. Bill. I really appreciate your professional assistance. If you do visit Singapore or Malaysia again, and you happen to like Durians, give me a message and I can bring you for some really good organic Kampung durians.
LINDA LOO, message dated Wed, February 25, 2015 7:40 pm PST
I tried some manual face massage and sure enough the results were dramatic and instant...and lasted the entire day.
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SG2PRO is like getting four bottles of nuskin future serums and using them for spa treatments. Wow.
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The magic is in pushing the research and technology where you want to go, making our formulas - our products - produce the healthy results the customer deserves.
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Pronunciation: /ˈôldis ˌlamp/
Definition of Aldis lamp in English:
A handheld lamp for signaling in Morse code.
Example sentences
- We flew just below cloud level, at 600 ft, until we spotted HMS Sheffield, which signalled to us with an Aldis lamp, giving us the bearing and the distance of the Bismarck.
- Ships also use flashing lights between vessels - the Aldis lamp - as another means of semaphore signalling.
- As we turned to the right downwind, I briefed the copilot to look for our clearance-to-land via the green Aldis lamp from the tower, since we had no radios.
World War I: named after A. C. W. Aldis (1878–1953), its British inventor.
Definition of Aldis lamp in:
- British & World English dictionary
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text:
Evo-stik Super Fix Putty product description
The Evo-stik Super Fix Putty is versatile hi-tech putty that has many uses.
Features & Benefits of Evo-stik Super Fix Putty
- Sets in just 10 minutes
- 50kg/cm2 Load bearing
- Fills, seals, fixes & repairs
Suitable For: General repairs Type: Putty Adhesives
Evo-stik Super Fix Putty
Cat code: 434969
Free Click & Collect
Delivery not available
Other customers who bought this also viewed
ReviewsEvo-stik Super Fix Putty 2 2Does the job.... As per the packing, takes a couple of hours to set and 24 hours to fully harden. I use around the house on curtain rails or coat hooks that need refixing. After 24 hours they are solid!!!! 25 April 2010Not the best!! Although this seems like a very intuative idea, it is does not do what is says on the tin. After having a crack in my bumper and getting advice instore i was advised to try this. It does not set in 10 mins as suggested, more like 2 hours to properly set. I sealed and repaired the bumper and after 2 hours moved the bumper only to find that slowly but surely the split came apart again. 22 February 20091-2 of 2
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Airline Ground Safety Panel (AGSP)
Through the OSHA and AGSP Alliance, both organizations are committed to providing AGSP members and others with information, guidance, and access to training resources that will help them protect the health and safety of workers, particularly by: 1) reducing and preventing falls; 2) addressing issues related to small businesses, motor vehicles, and hazard communication; and 3) understanding the rights of workers and the responsibilities of employers under the Occupational Safety and Health Act (OSH Act).
Through the Alliance, the organizations will use relevant injury and illness data in selected industries to help identify areas of emphasis for Alliance awareness, outreach, and communication activities. The Alliance will also explore and implement selected options to evaluate the effectiveness of the Alliance and measure the impact of its overall effort on improving workplace safety for employers and workers. In renewing this Alliance, OSHA and AGSP recognizes that OSHA's State Plan and On-site Consultation Project partners are an integral part of the OSHA national effort. The Alliance's goals include:
AGSP participants intend to work together on the following training and education activities:
NOTE: The AGSP Alliance will explore the use of electronic media where it is feasible. (e.g., webinars, videos, etc.)
AGSP participants intend to work together on the following outreach and communication activities:
AGSP participants intend to work together on the following rulemaking and enforcement activities:
*Accessibility Assistance: Contact OSHA's Directorate of Cooperative and State Programs at (202) 693-2200 for assistance accessing PDF materials.
All other documents, that are not PDF materials or formatted for the web, are available as Microsoft Office® formats and videos and are noted accordingly. If additional assistance is needed with reading, reviewing or accessing these documents or any figures and illustrations, please also contact OSHA's Directorate of Cooperative and State Programs at (202) 693-2200.
**eBooks - EPUB is the most common format for e-Books. If you use a Sony Reader, a Nook, or an iPad you can download the EPUB file format. If you use a Kindle, you can download the MOBI file format.Back to Top
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Play any type of Game at Y8.com. The biggest Game Collection to play free online. Flash, Unity 3D, Html5, Android, Java and Shockwave.
If the game freezes, just click inside it (games can get unresponsive if you click elsewhere on the page).
Baby Juliet went to the park and ate a lot of sweets including icecream and candies. Now her teeth hurt and you have to give her back the perfect smile by whitening her teeth and implant new ones if it is needed.


text:
|Ventilone Patent applications
|Patent application number
|Process of Control of the Storage of Thermal Energy in the Ground and Associated System - A process of control of a thermal energy storage unit in the ground includes heat exchangers buried in the ground, each of the exchangers allowing a calorific energy exchange between a heat-conveying fluid traversing it and the ground, the energy storage unit being at the interface between a source and consumer of calorific energy to store thermal energy. One measures the temperature in various points of the ground using buried temperature gauges, the temperatures and flow of a heat-conveying fluid in input and output of the source to determine the thermal power provided by the source, and temperatures and flow of a heat-conveying fluid in input and output of the consumer to determine the thermal power to provide the consumer. One optimizes the storage of thermal energy in the storage unit by selecting active exchangers among the plurality of exchangers according to temperature measurements, flow measurements and thermal power measurements.


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Featured news
Identifying P2P users using traffic analysis
With the emergence of Napster in the fall of 1999, peer to peer (P2P) applications and their user base have grown rapidly in the Internet community. With the popularity of P2P and the bandwidth it consume, there is a growing need to identify P2P users within the network traffic.
In this paper the author will propose a new method based on traffic behavior that helps identify P2P users, and even helps to distinguish what type of P2P applications are being used.
By Yiming Gong at SecurityFocus.
[ Read more ]
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text:
Tagging is a lot more difficult than it looks. Prior to starting this blog I hadn't spent much (if any!) time tagging anything – not virtually anyway. While adding tags to my blog postings I keep questioning myself: Did I use "library" or "libraries" previously? Does it matter if I capitalize – will my tag cloud know that it's the same tag? How many tags is too many tags ? How many is too few? What distinguishes tags from categories? Ughhh!!!!
I'm starting to think that maybe I'm a controlled vocabulary kind of person…. The kind of person comfortable with lots of structure – and drop down lists! Multi-pick please!
I just listened to a one-hour presentation Jason Griffey put together for a "Five weeks to a social library" workshop called "Make your library del.icio.us: social bookmarking in the stacks." In the presentation, he talks about how tags are essentially uncontrolled vocabularies from which folksonomies accidentally arise. I'm sure this is the case in almost all instances with the possible exception of how the San Mateo Public Library is using del.icio.us. As you can see from the image at the right, they are using the Dewey Decimal Classification system to organize their tags! Is this crazy? To try to force a classification system onto what is supposed to be a free for all? Ok. Maybe I'm getting hysterical here, but it does seem a little odd and ingenious at the same time.
The library has managed to slot almost all their bookmarks into a Dewey classification and for those which aren't a good fit, del.icio.us gives them the flexibility to add whatever makes sense. For example, the library has quite a few classifications in the 600s for business-related websites but they have also added a "buslib" entry to capture all the sites they think should be included in a business library.
So how do patrons of the San Mateo Public Library use these social bookmarks? They don't! Try as I might, I could not find a link on their website to del.icio.us or to bookmarks or tags. They have a Website Resources page but it does not refer to the bookmarks on Delicious. So I google "how san mateo uses delicious" and learn from a blog that only staff use the San Mateo del.icio.us page – that 's the reason for the Dewey. This blog posting was back in 2006 and while the bookmarks have been maintained and are added to, I can't tell if the library has taken steps to make this tool part of how they interface with their patrons as yet.
Boy, this isn't easy! I've been going through library websites and library delicious sites trying to figure out how library patrons are benefiting from the use of social bookmarking services by their public libraries. Either the libraries haven't actually integrated the two tools (the website and the booking services), or the integration is so seamless I can't tell (which is entirely plausible). I've been using a very helpful blog post to help me find libraries using del.icio.us, and came across Chelmsford Public Library that uses del.icio.us for its bookmarks and its subject guide, but try as I might I see from the CPL's web interface how the two are integrated. Although I do know it was actually done thanks to the Swiss Army Librarian who did work. The library's website has multiple pages that reference web resources, from the community pages to the reference department pages. It is possible, and likely, that all of these are drawing their links from del.icio.us but I can't confirm it.
What I can confirm is how Alameda County Public Library is using their del.icio.us bookmarks on their website. The library is providing to their patrons web resources which have been previously scrutinized by librarians and grouped by topic. They are using sites they've tagged using del.icio.us to provide library patrons with reputable web resources. Certainly one of the most common complaints about the internet is that there is so much information that it is impossible to wade through and to extremely difficult to decide what is an authoritative resource and what isn't. Here the Alameda County librarians are taking a lot of the guesswork out of the internet for its library patrons, and they are doing it easily and effectively with the help of a service like del.icio.us.


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- Secure Storage Containers in Westborough, MA.
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Matthew Scallen Hungry Horse, MT (47 yrs old)
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Synonyms of password in English:
word of identification, sign, signal, word;
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text:
Latest Activity: Played Kongai (11 hours ago)
Points needed for next level: 216 Level
Ditched all coding for kong. Bots are obsoleted. Working on something more mainstream with the same group. Slow progress but making some daily. If you're a coder and interested in helping to make a cross-platform hybrid language for game engines. Contact me. Strong knowledge of c/c++ and either c# and/or vb.net needed. OpenGL and Sockets, along with 2d and 3d game engine concepts a huge plus. The group is in this for fun, no pay, and eventually going to open source the tool base once it's ready. In other words… no compensation… must enjoy programming, be cordial, and sensible. The group meets on skype daily.
Current members:
Adark [Active, lua/Roblox Scripting]
AndriaDawn [Lead Inspirator, budding programmer…]
Atomspk [inactive]
Donteatglue1 [Budding biologist]
Filthy_Casuals [silent observer]
GGPPJJ [Founder, admin/operating systems, hardware, servers]
Hongbot [inactive]
Jiyaianin [troublemaker…]
Kenata [Active, objC, c/c++, swift (mac and mobile)]
Kiataryu [silent observer]
Mutikt [Founder, vb.net/c#, c/c++]
Noobmasterz [inactive]
Organization13 [inactive]
PDrifting [Founder, Lead Programmer, c/c++, c#/vb.net, pascal]
Shadowsora [inactive]
The_Real_XavZz [silent observer]
Ultamahobo [active, java, c/c++, python]
Most of the members are casual. No pressures… real life always takes precedence.
Activity Feed
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Are you Mei-Xiang Sang?Claim your profile
Publications (8)17.7 Total impact
Article: The tumor-suppressive function of miR-1 by targeting LASP1 and TAGLN2 in esophageal squamous cell carcinoma[Show abstract] [Hide abstract]
ABSTRACT: Objective: This study determined the expression of microRNA-1 in esophageal squamous cell carcinoma (ESCC) tissue and cell lines to evaluate its effects on clinicopathological parameters and its target gene LASP1, TAGLN2. Methods: The expression of miR-1, lasp1 and tagln2 were detected in 55 ESCC tissues and adjacent normal tissues by RT-PCR. The association between miR-1, lasp1 and tagln2 expression and clinicopathological characteristics was observed. MicroRNA-1 (mimics-miR-1) and its inhibitor (Inhibitor-miR-1) were transfected into esophageal cancer cells KYSE 510 and Eca 109; cell proliferation, migration and invasion assays were carried out. Plasmid construction and dual-luciferase reporter assay were also carried out to indicate whether LASP1 and TAGLN2 were miR-1 target genes. The expression LASP1 and TAGLN2 were detected with Western blot methods in cell lines, by immunohistochemistry in ESCC tissue. Results: The gene expression level of microRNA-1 in cancer tissues were significantly lower than that in adjacent normal tissues (P < 0.01). The expression of miR-1 in ESCC was correlated with involvement of lymph nodes (P = 0.002), histologic classification (P = 0.000) and vessel invasion (P = 0.022). The expression of lasp1 and tagln2 increased in cancer tissues compared with in adjacent normal tissues (P < 0.05). MiR-1 suppresses the cell growth, migration and invasion in vitro. The expression of LASP1 and TAGLN2 decreased in mimics-miR-1 transfected cells, and increased in inhibitor-miR-1 transfected cells. Luciferase reporter assay confirmed that LASP1 and TAGLN2 mRNA actually had the target sites of miR-1. Conclusions: miR-1 suppresses cell proliferation, invasiveness, metastasis and progression of ESCC by binding its targeted gene LASP1 and TAGLN2. This article is protected by copyright. All rights reserved.
Article: Low-dose decitabine induces MAGE-A expression and inhibits invasion via suppression of NF-κB2 and MMP2 in Eca109 cells[Show abstract] [Hide abstract]
ABSTRACT: Decitabine, a demethylating drug, is the first-line treatment for myelodysplastic syndromes and gains better overall survival, which is based on epigenetic mechanism. Activated by promoter demethylation, melanoma-associated antigens-A (MAGE-A), cancer-testis antigens are attractive targets for immunotherapy. Our purpose was to investigate whether decitabine could show anti-tumor effects for esophageal cancer and explore its mechanism. In addition, we aimed to examine its modulation for most MAGE-A members. The results showed the baseline expression were MAGE-A2, -3,-9, and -10 in Eca109 cells and decitabine (0.5 μM) could induce MAGE-A8 and -4 whereas reduce MAGE-A9 and -10. Moreover, decitabine (0.5 μM) inhibited cell proliferation, migration and invasive ability by 15%, 34% and 47.2%, respectively and decreased expressions of NF-κB2 and MMP2. Our results demonstrated that low-dose decitabine induced the expression of MAGE-A8 and -4, and inhibited cell invasion through decreasing expression of MMP2 and NF-κB2, which provides possibilities for combing decitabine with immunotherapy targeting MAGE-A to treat advanced esophageal squamous cell carcinoma.
- [Show abstract] [Hide abstract]
ABSTRACT: The MAGE gene encodes cancer/testis antigens that are selectively expressed in various types of human neoplasms but not in normal tissues other than testis and placenta. However, the expression pattern of MAGE-A9 and MAGE-A11 in breast cancer patients is still unclear. The purpose of our study is to investigate the expression pattern and mechanism of MAGE-A9 and MAGE-A11 in breast cancer patients. The expression of MAGE-A9 and MAGE-A11 was investigated in 60 breast benign diseases specimens, 60 tumor-free breast specimens and 60 breast cancer specimens by RT-PCR, and their correlation with clinicopathological parameters was elucidated. We examined the influence of the DNA methylase inhibitor 5-aza-2'-deoxycytidine (5-aza-CdR) together with the histone deacetylase inhibitor trichostatin A (TSA) on the expression of MAGE-A9 and MAGE-A11 genes in two breast cancer cell lines. The expression rates of MAGE-A9 and MAGE-A11 in breast cancer specimens were 45 and 66.7%, respectively. MAGE-A9 and MAGE-A11 expression was positively associated with estrogen-receptor (ER) and HER-2 expression (p <0.05). 5-Aza-CdR treatment alone could induce the expression of MAGE-A9 and MAGE-A11 in cell lines that did not express this antigen. TSA treatment alone had no influence on MAGE-A9 and MAGE-A11 gene expression. However, TSA was able synergistically to enhance 5-aza-CdR-mediated MAGE-A transcription (p <0.05). Our data show that MAGE-A9 and MAGE-A11 are tumor-specific antigens and not only DNA hypermethylation but also histone deacetylation is responsible for the mechanism underlying MAGE-A9 and MAGE-A11 gene silencing.
Article: An Ester Extract of Cochinchina Momordica Seeds Induces Differentiation of Melanoma B16 F1 Cells via MAPKs Signaling[Show abstract] [Hide abstract]
ABSTRACT: Cochinchina momordica seeds (CMS) have been widely used due to antitumor activity by Mongolian tribes of China. However, the details of the underlying mechanisms remain unknown. In the present study, we found that an EtOAc (ethyl ester) extract of CMS (CMSEE) induced differentiation and caused growth inhibition of melanoma B16 F1 cells. CMSEE at the concentration of 5-200 μg/ml exhibited strongest anti-proliferative effects on B16 F1 cells among other CMS fractions (water or petroleum ether). Moreover, CMSEE induced melanoma B16 F1 cell differentiation, characterized by dendrite-like outgrowth, increasing melanogenesis production, as well as enhancing tyrosinase activity. Western blot analysis showed that sustained phosphorylation of p38 MAP accompanied by decrease in ERK1/2 and JNK dephosphorylation were involved in CMSEE-induced B16 F1 cell differentiation. Notably, 6 compounds that were isolated and identified may be responsible for inducing differentiation of CMSEE. These results indicated that CMSEE contributes to the differentiation of B16 F1 cells through modulating MAPKs activity, which may throw some light on the development of potentially therapeutic strategies for melanoma treatment.
Article: [Effect of microRNA-mediated p65 gene silencing on the proliferation and apoptosis of human breast cancer MDA-MB-231 cells].[Show abstract] [Hide abstract]
ABSTRACT: To explore the effect of microRNA (miRNA)-mediated p65 gene knockdown on the proliferation and apoptosis of human breast cancer MDA-MB-231 cells. p65-targeted miRNA plasmid was constructed and transfected into MDA-MB-231 cells via lipofectamine(TM)2000. The expression of p65 gene in the transfected cells at the mRNA and protein levels were detected by RT-PCR and Western blotting, respectively. The cell proliferation and apoptosis were measured by MTT assay and flow cytometry (FCM), respectively. The expressions of apoptosis-related proteins were detected by Western blotting in the transfected cells. Compared with the negative control group, the expressions of p65 mRNA and protein in p65miRNA-trasnfected cells were significantly down-regulated (P<0.05). MTT assay showed significantly lowered viability of MDA-MB-231 cells after the transfection (P<0.05). FCM showed an increased cell apoptosis rate in p65miRNA group compared with that in the negative control group (P<0.05). Caspase-3 and PARP were both cleaved into their active forms and the expression of these active forms was increased in p65miRNA group. The miRNA targeting p65 gene can inhibit the proliferation and induce apoptosis of breast cancer cells, and p65 gene might become a new target in gene therapy for human breast cancer.
Article: Potential biomarkers for esophageal carcinoma detected by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry[Show abstract] [Hide abstract]
ABSTRACT: Currently, no satisfactory biomarkers are available to screen for esophageal squamous cell carcinoma (ESCC). The goal of this study was to find biomarkers and establish a serum protein fingerprint model for early diagnosis of ESCC using the ClinProt protocol of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Serum samples were collected from 62 patients with ESCC, nine patients with esophageal adenocarcinoma (EA) and 38 healthy individuals. Proteomic spectra of mass to charge ratio (m/z) were generated following the application of plasma to weak cationic-exchanger magnetic beads (WCX-MB). The spectral data were analyzed using a support vector machine, and potential biomarkers were chosen for system training and used to construct diagnostic models. Three differential patterns were established using MALDI-TOF MS. Pattern 1, consisting of 11 protein peaks, separated ESCC patients from the healthy individuals with a sensitivity of 90.0% and a specificity of 88.4%. Pattern 2, consisting of eight protein peaks, separated ESCC in stage I and stage II from stage III and stage IV with a sensitivity of 92.9% and a specificity of 82.3%. Pattern 3, consisting of seven protein peaks, separated ESCC from EA with a sensitivity of 91.3% and a specificity of 80.0%. These results suggested that MALDI-TOF MS combined with MB separation yields significantly higher sensitivity and specificity for the detection of serum protein in patients with ESCC.
Article: [Celecoxib promotes apoptosis of breast cancer cell line MDA-MB-231 through down-regulation of the NF-kappaB pathway][Show abstract] [Hide abstract]
ABSTRACT: Celecoxib can inhibit cell proliferation, regulate cell cycle and induce apoptosis, but the underlying mechanisms are still unclear. This study was to investigate the association between the NF-kappaB (kappaB) pathway and the apoptosis of breast cancer cell line MDA-MB-231 induced by celecoxib. The expression of cyclo-oxygenase-2 (COX-2) mRNA was detected by reverse transcription polymerase chain reaction (RT-PCR). Cell proliferation and cell cycle were detected by MTT and flow cytometry (FCM), respectively. The protein expressions of caspase-3 and p65 in MDA-MB-231 cells were detected by western blot. After incubation with different concentrations of celecoxib for 48 h, COX-2 mRNA expression in MDA-MB-231 cells was decreased in a dose-dependent manner compared with untreated cells (P<0.05). Proliferation of MDA-MB-231 cells was reduced drastically in a dose-and time-dependent manner after celecoxib treatment (P<0.05). Combination of prostaglandin E2 (PGE2) and celecoxib exerted similar inhibition effect to celecoxib alone on cell growth (P>0.05). High-dose celecoxib induced an increase in the percentage of G0/G1 phase cells accompanied by the change in DNA ploidy. The cellular caspase-3 level was enhanced whereas the p65 level was decreased in celecoxib-treated MDA-MB-231 cells after 24 h in comparison to those in the control cells. Celecoxib could inhibit MDA-MB-231 cell proliferation and promote cell apoptosis by down-regulating the NF-kappaB signaling pathway.
- [Show abstract] [Hide abstract]
ABSTRACT: p53 gene is the main regulator of 14-3-3sigma. Activated p53 could induce the expression of 14-3-3sigma, while 14-3-3sigma stabilizes the expression of p53 and enhances its transcriptional activity. p63 and p73, the members of p53 family, also have some functions similar to p53. This study was to investigate the effect of 14-3-3sigma on the transcriptional activity of p73. Luciferase reporter assay, reverse transcription-polymerase chain reaction (RT-PCR), and Western blot were used to evaluate the effect of 14-3-3sigma on the transcriptional activity of p73 in p53-deficient human lung carcinoma cell line H1299. Colony formation test was used to evaluate the effect of 14-3-3sigma on the transcriptional activity of p73 in p53-mutant human breast cancer cell line MDA-MB-436. The luciferase activities induced by bax and p21WAF1 promotors were significantly higher in p73-transfected H1299 cells than in control H1299 cells (P<0.01), and were further increased by the transfection of p73 (25 ng) and 14-3-3sigma (100, 200, and 400 ng) in a dose-dependent manner (P<0.01). The expression of bax and p21WAF1 were higher in p73-transfected H1299 cells than in control H1299 cells, and were significantly higher in p73-and 14-3-3sigma-transfected H1299 cells than in p73-transfected H1299 cells (P<0.01). The number of colonies was fewer in p73-transfected MDA-MB-436 cells than in control MDA-MB-436 cells, and the colonies were significantly smaller in p73-and 14-3-3sigma-transfected H1299 cells than in p73-transfected H1299 cells (P<0.01). 14-3-3sigma can enhance the transcriptional activity of p73 in a dose-dependent manner.
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Hebei Medical UniversityChentow, Hebei, China


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Join Date: Aug 2003
Location: Vermont
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|Originally posted by AmandasMom
I dunno, maybe its the pregnancy hormones, but im tired of these "guest judges" who are there pimpin' a new CD out or something. I wasn't blown away buy anyone tonight, a few were great, but no chills like I had last week...
|Originally posted by Moss's Mommy
OK, now I've decided that it might not be the best idea for me to watch this show anymore, seeing how I never tend to agree with the status quo on many ideas. I think I'm just setting myself up for huge dissappointments here. DUH..... I don't like listening to the radio, it makes me want to barf, and I expect the people I think are talented to win????
|Serial posting to add that I can't believe they put George in the position of having to decide which group was in the top when Ryan told him to go stand with the group with the most votes. He stood there looking confused and did what I probably would have in that situation, gone with Group A , bc they were considered the better singers AND the first group.
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Gentoo 2008.0 with New Installer
After some turbulence concerning the status of the foundation and many delays, the free Gentoo project has revamped its Linux distribution and released version 2008.0.
In October 2007, the State of New Mexico, where the project resides, originally withdrew the foundation's status due to various formal errors. A number of sponsrs withdrew and Gentoo's founder Robbins was forced to issue a plea for help. These issues also impacted the development of the operating system itself and version 2007.1 was omitted. The foundation regained its status in mid-May and the developers can now go on with their work on the operating system.
In early April the project team released the beta version, and now the final version 2008.0 has been released. Besides updates for various software packages, the programmers say that the most important development is the new installer, improved hardware detection and revamped profiles. Because the installer now uses the packages and ebuild tree from the live CD, the installation will now complete without an Internet connection. The fact that Gentoo has moved to kernel version 2.6.24 means that more hardware drivers are available. Reworking of profiles in Gentoo 2008.0 has helped to reduce redundancies and thus facilitate future development work. From the user's point of view, the profile directories have changed: more information is available on the project's upgrade page. To reduce space requirements, the developers are using the Xfce interface instead of Gnome for the live CD version of version 2008.0 and later. The project team decided not to produce a live DVD for timing reasons.
Gentoo Linux claims to give users easy system configuration and customization options. Gentoo 2008.0 is now available for various platforms from the project page.
IndeedDonnie is correct.
The Gentoo Foundation's lapse in official status had absolutely nothing to do with any release delays. The primary reason for the delays and the cancellation of 2007.1 were purely manpower-related. Even if the Foundation had completely ceased to exist, we still would have canceled 2007.1 and come out with 2008.0 in the exact same manner. The Gentoo Foundation has exactly *ZERO* to do with the day-to-day operation and development of Gentoo Linux. The Foundation is simply an intellectual property container and a bank account.
Some clarificationsTo my knowledge, no sponsors withdrew, and we actually gained a new sponsor. Additionally, although 2007.1 was canceled, it was because of things directly related to the release process rather than the foundation, which has essentially zero impact on development of the distribution.
Developer, Gentoo Linux
Blog: http://dberkholz.wordpress.com
Issue 184/2016
Buy this issue as a PDF
Google Announces End to Flash Ad Support
Upcoming switch to HTML5-only ads is further evidence the Flash is entering its final days.
President Obama Launches New Cyber-Security Initiative
US government invests $19 billion on enhancing security and replacing ancient computer systems.
Linux Foundation Eliminates Individual Membership
But you can still be a non-voting "individual supporter" if you pay the money
Secret Backdoor Affects More Fortinet Firewalls
Several current systems could fall victim to the attack
Linus Announces Linux Kernel 4.4
Latest Linux engine comes with better graphics and support for Intel's new power-saving chips.
Mass Poem Greets Web Admins
Hackers send a message of beauty and liberation to server logs
Raspberry Pi Becomes a Thin Client
Citrix gets excited about new Pi-Powered XenDesktop client system
Microsoft Offers Linux Certification
Linux on Azure cert heralds a new era for Redmond.
CeBIT 2016: Call for Open Source Contributions
Proposals for presentations at the CeBIT Open Source Forum will be accepted through 24 January 2016.
Gone in a Flash
Adobe looks for a new start; renames its embattled Flash tool.


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Best Songs We Heard This Week: Lana Del Rey, Jess Glynne, DNCE and More
From Lana Del Rey to Joe Jonas, these are the songs we haven't stopped spinning all day.
From Lana Del Rey to Joe Jonas, these are the songs we haven't stopped spinning all day.
From Ariana Grande to Brandon Flowers to Justin Bieber, we're counting down some of the best songs of the year.
Kylie Minogue just dropped her new single, 'Into the Blue,' which will appear on her upcoming album 'Kiss Me Once.' It's her twelfth album, and the pop diva has not lost a step this deep into her illustrious career.
Kylie Minogue makes 44 look good on her double covers for the January 2013 issue of ELLE U.K.. On one cover, Minogue is white hot with platinum blond locks and a white mini dress with an architectural bodice. On the other, it's a black and white, close up of her beautiful face, with her hair slicked back. She looks positively stunning!
It's a battle of the blondes!
Kylie Minogue reigns supreme at the top of the pop music food chain in Europe, namely in England. Since she knows a thing or two or 10 about pop divadom, she was put on the spot by host Andy Cohen for the 'Plead the Fifth' interview segment on Bravo's 'Watch What Happens Live.' Cohen bravely asked Minogue who has more talent: Lady Gaga or Madonna?
Kylie Minogue, easily one of the biggest European pop stars ever, has the blues on the cover of the July issue of Glamour U.K. — and boy, do we want what she's got.
Kylie Minogue honored Queen Elizabeth II with a special medley of hits on Monday (June 4), at the Diamond Jubilee concert in London, England, celebrating Her Majesty's 60-year reign.
Before her new album is released, Madonna may be hooking up with Kylie Minogue for a superstar collaboration in the coming months.


text:
Zaraki Kenpachi by VoqusWatch
©2012-2016 Voqus
Bleach - Zaraki Kenpachi signature.
Great work here
Ah i remember working with this render once, you really have to get the perspective right on this one otherwise it falls to pieces. effects can be even brighter on it and more versatile but good job on this.
Wow, awesome
very well done ^^


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Linux New Media Awards 2005
Linux New Media put together an international jury to recognize outstanding contributions to Open Source. We'll tell you who brought home the prizes when the 2005 Linux New Media awards were presented at Linux World Frankfurt.
Linux New Media invited an international jury of some 200 members to acclaim outstanding contributions to free software. Besides developers, authors, and industry experts, the 2005 jury also included representatives from public administration, an area in which Open Source software is steadily gaining momentum. Trend to VoIP The award categories reflect current trends. The free PBX application, Asterisk (http:// www. asterisk. org), attracted a majority in the new "Best Voice over IP software" category, followed by Skype, http:// www. skype. com, for many the first program to bring Internet Protocol-based communication to the home.
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Click on any picture to see a larger size. Works and posts on this blog are © William J. Charlebois unless otherwise noted. I'd love it if you would check out my classes on my web site. The link is: http://wcharlebois.wix.com/purplemooseheartart See you there!
Thursday, June 5, 2014
Healing The Darkness
Free verse by me. Overlay from 2LilOwls' "Sampler." Man googled. Splatters from Tangie Baxter's "You Are Magnificent." Sunburst from BA "Orange."
5 comments:
This is very nice, Bill! I'm wishing lots of days in the sun to replenish your spirit after the winter we had!!!ReplyDelete
Hope you are having a sunny and joyful weekend!ReplyDelete
I love your verse and the picture accompanying it. Perfect blending and layering.ReplyDelete
Awesome dear friend! Love the verse and a perfect illustration! xxReplyDelete
Amazing how you are able to add magic to an image.ReplyDelete
Wish you many peaceful moments like this one ~ clothed or not.
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