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Article | March 31, 2001
Diagraph, An ITW Company: Laser coders
Diagraph (St. Louis, MO) will now distribute Xymark small-character laser coders in the United States. The coders mark up to 430 characters/second of text or graphics on glass, plastic, rubber, preprinted or coated substrates without using consumables such as inks or solvents.
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Featured news
Study: ID fraud in decline
Despite high-profile data breaches, identity fraud may be on the decline, according to a study released on Thursday.
The study, based on 5,000 telephone interviews, found that identity fraud has dropped about 12 percent within the sample set, which translates to an overall drop of some $6.4 billion in costs from the crime, according to Javelin Strategy & Research, the analyst firm that conducts the study every year.
At SecurityFocus.
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http://lowkickmma.com/author/Jizzle11 Jizzle11
We don't really know if Brock would be his #1 competitor… there's unfinished business in the ufc heavyweight division
http://lowkickmma.com/author/bjfanvad bjfanvad
I agree that there is unfinished business in the UFC. However, they both are current champion's and when you mix match organizations you usually match up the champions.
http://lowkickmma.com/author/friendlyfoe friendlyfoe
I am disappointed (but still optimistic in a way) to think that this fight may never ever happen due to two parties wants and needs….Though, I still believe that Brock's shear size and athlethism is no match to Fedor's skill and techinique
http://lowkickmma.com/author/MereDictum MereDictum
Until it happens, it's all just hype and speculation. I love watching the detractors vs. the worshipers. It's silly to me that people get so entrenched one way or the other. Just like any other fight on their level, you never know until fight night who is the better man. He's not a fraud but then again he's no "Emperor" of this sport. He's just up there in the top 10 and no better or worse than the other guys on any given night.
We shall see.
http://lowkickmma.com/author/UrHype UrHype
As said, remains to be seen. The huge size of todays UFC HWs will become a factor though.
http://lowkickmma.com/author/Krogan Krogan
Must be one of the lamest and most partial videos I have ever seen, guy knows nothing about the history of MMA.
People that know what they are talking about knows that Fedor has beaten everyone in their prime except for those few fighters currently in the UFC.
http://lowkickmma.com/author/bjfanvad bjfanvad
I may know a thing or too, but I don't think Arlovski was in his "prime". It's also very easy to claim, "He's over the hill now." . You hear that a lot by the same fools like you that claim Nog is "Over the hill".
Everything in that video is obviously opinion. There is no doubt that it is partial to Brock's claims of success. But the fact's are there. Cry as you might, but we will find out if it happens..
http://lowkickmma.com/author/UrHype UrHype
Cain, Brock, Carwin, Mir,Barry, …might check again man, theres more than a few he can to step up to, and thats just off the top of my head.
http://lowkickmma.com/author/KYMAN KYMAN
this video is correct in all aspect Fedor wont b able to stop Brock … i dont think he can beat Cain either or mir …Fedor is a 2bit hack that is lead by LEASH
http://lowkickmma.com/author/Leftty81 Leftty81
Fedor was offered the most lucrative contract in UFC history. That says it all dip shits! Oh and it was a chance to fight Randy, he was champion at the time, Lesner was plan B. By the way who has Brock beaten, what's his record? He's a one dimensional fighter if I ever saw one, kinda like Marck Coleman but bigger, his size is all he has going for him. Fedor isn't owned by the UFC cause that's what happens when you sign. He's not fighting the best competition now but that's no reason to bash him, the biggest reason I am a Fedor fan is his respect towards all fighters, something Brock needs to learn. This isn't WWE.
http://lowkickmma.com/author/bjfanvad bjfanvad
Sometimes size is enough. If Fedor couldn't stop Brett Rogers from some ground and pound, imagine what Brock would do to him.
Brock was able to keep Frank Mir, who has way better ground skills than Fedor, on the ground and pounded.
Fedor's only chance would be in a striking game. I doubt because of Brock's size, Fedor would be able to keep it there.
Your right, this isn't the WWE. It's MMA and they are fighters. If you didn't know it, fighters talk a lot of trash. Some of the biggest trash talkers still go up and put on a "humble" press conference/interview.
Brock speaks his mind and so far has been able to back it up.


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It looks like you're parked near campus. If I had been walking by, I would have helped get that cock hard and get it off with my mouth!
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Hospital honors its 'humanitarian'
Huot's residency program trains Waterbury's doctors
|Dr. Stephen Huot, medical director of the Yale Internal Medicine Residency Program at Waterbury Hospital, will be honored at the gala Saturday with the 2013 Humanitarian Award. Darlene Douty / Republican American
As he finished his medical training at Yale-New Haven Hospital nearly 25 years ago, Dr. Stephen Huot itched to begin his career as a researcher.
First, however, he had a mountain of debt to repay. Instead of moonlighting in an emergency room to make ends meet, Huot volunteered to help start a residency program between Yale and Waterbury's two hospitals. Huot put the grant money he had received for physiology research in an escrow account, and got to work on the fledging program.
"It was a real career change," Huot, 58, recalled.
Within two years, he was named director of the Yale Internal Medicine Residency Program — and he never looked back. Since it started in 1989, the program has trained more than 400 doctors, many of whom practice in Waterbury.
On Saturday, Waterbury Hospital will recognize Huot as the hospital's "humanitarian of the year" at the 14th Annual Waterbury Hospital Gala. The award recognizes outstanding volunteer or clinical service to the hospital.
David Podell, chairman of medicine at Waterbury Hospital, said the Waterbury community is in better health thanks to the talented physicians Huot has recruited and helped train. Podell described Huot as the type of person others constantly look to for advice.
"The residents all love him and seek him out for career decisions and support, and he will support you, even if you decide to do a 180-degree about-face and change programs. He will respect you for that," Podell said. "He is a great problem solver and leads with consensus. When he is looking to make a decision, we all feel like we decided together. Members of the faculty are constantly saying, 'Let's ask Steve.'"
Perhaps Huot's leadership skills can be traced back to his childhood, growing up in Manchester, N.H., the second oldest in a brood of seven children born to a newspaper printer father and an accountant mother.
His extended family was peppered with nurses and he took an early interest in science.
"I was curious to figure things out, to experiment and reason through problems," said Huot, who lives in Hamden with his husband, Marc.
Huot studied humanities and biology at Saint Michael's College in Vermont and earned his medical degree from Duke University School of Medicine in 1985. He also has a doctorate in physiology, which is pegged to his fascination with how the body works and his original hope to pursue a career in research.
Huot came to Yale for his internal medicine residency, followed by a fellowship specializing in nephrology, or the study of kidney diseases. Just as he was finishing his fellowship in 1989, the opportunity to help start the residency program in internal medicine arose.
"I signed up for two years to help supplement my income, but I really ended up enjoying the educational contact," said Huot, who has two grown sons.
The program came at a fortuitous time. In the mid-80s, fewer medical school graduates were pursuing careers in internal medicine, in favor of specialties like oncology and dermatology.
"This was an opportunity to offer our residency candidates (more training in primary care)," Huot said.
Each year, 16 residents are chosen for the three-year program and spend about two-thirds of their time at Waterbury Hospital and its Chase Outpatient Center. (Saint Mary's Hospital stopped participating in the Yale residency program in 2005.)
Huot is most proud of the annual Community Health Fair the residency program started in Waterbury. In partnership with the Greater Waterbury YMCA, the residents offer free blood pressure and cholesterol checks, screen for diabetes, measure body mass and answer general questions.
Making sure that people have a relationship with a primary-care physician is important to Huot.
"Everyone can think of a family member who has been ill and there was a physician who took the quarterback role in talking to the kidney doctor or the heart doctor," Huot said. "There is less frustration when you have that central role of primary-care physician. And there is a shortage of them now. The field needs to be one where they can earn fair income and work structured hours."
Huot said he believes policy changes are needed to address these issues.
"If politics doesn't mess it up, I think we can do that, especially with the pressure now to control the costs of health care," he said. "We need to start paying for (quality of care) offered, not the number of tests doctors can do."
Looking back at his career trajectory, Huot knows his roots in research were not wasted.
"I like identifying the right question to ask and how to ask it," he said. "That's very applicable to teaching and clinical medicine and has enriched who I am."
Contact Carrie MacMillan at firstname.lastname@example.com.
If you go
Waterbury Hospital's 14th Annual Gala will be Saturday at Aria Wedding & Banquet Facility in Prospect starting at 5:30 p.m. Tickets are $175 and proceeds will benefit the hospital's Medical and Surgical Residents' Education Fund. Information: 203-573-6083.
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STARmeterSEE RANK
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Tun Fei Mou
Tun Fei Mou was born on May 13, 1941 in Shandong, China. He is a director and actor, known for Men Behind the Sun (1988), Men Behind the Sun 4 (1995) and Lost Souls (1980). See full bio »
Born:in Shandong, China
More at IMDbPro » Represent Tun Fei Mou? Add or change photos


text: im trying to calculate the drop force of falling object. we do drop test at my work and believe the figures are wrong. we drop a 24.75lb weight from different heigths to check parts . they have it now set that dropping the given weight from 1 ft only produces 24.75 ft/lb force and they add 24.75 for each foot after that. I came up with around 74.86ft/lb at 1 foot. 24.75 seems low at 1 foot. any help is appreciated. brandon


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8/22/2006 10:25pm, #1
- Join Date
- Jan 2005
- Posts
- 240
Ernesto Hoost on Japanese TV show
Before anyone says anything, this is Martial Arts related and Comedy (as per the forum description)
Apparently the object of this game show is to not speak a word while you are being made to smell a really bad smell, having a nose hair plucked, or other types of hilarious torture.
Giggling is allowed, but I don't think talking is.
Plus Hoost singing Karaoke at the end.
8/22/2006 10:26pm, #2--
awesome show. they need to make some knid of japanese tc channel over here, i wouldnt watch anything else
8/23/2006 12:18am, #3--
Most Extreme Challenge anyone?
The Japanese are a hit or miss for me. Game shows are normally a hit. I don't need to remind anyone about the Bob Sapp vs group of small asian schoolgirls do I?
8/23/2006 12:23am, #4
- Join Date
- Jun 2006
- Location
- Moscow, ID
- Posts
- 12
It's a little unnerving that the same guy who giggles uncontrollably when someone is forced to sniff a fart out of a bag is the same one who could knock you out with any limb he chose. And I mean any limb...
8/23/2006 12:33pm, #5
--Originally Posted by TehDeadlyDimMak
- Join Date
- Jan 2005
- Posts
- 240
Basically Bob was covered with some foam balls, the object of the game was for the girls of the group to grab them off of Bob while he tried to stop them.


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Previous Episode | Next Episode
Orgon GrindorOrgon Grindor (1996) - Dial M For Monkey Cartoon Episode Guide by Dave Koch
This page has been viewed 10 times this month, and 1128 times total.
- Dial M For Monkey Cartoon Episode GuideEpisode GuideTelevisionSeriesCartoon
- Hanna-Barbera Productions, Rough Draft Studios
- Distributed by: Cartoon Network
- Cartoon Characters: Monkey, Agent Honeydew, The Commander, Organ Grinder, Rat, Fat Kid, Officer, Balloon Man, Man In Booth, Kids, Guys.
- Voice Actors: Frank Welker, Paula Tico, Kath Soucie.
- Directed By Paul Rudish, Genndy Tartakovsky.
- Produced By Davis Doi, Buzz Potamkin, Genndy Tartakovsky, Sherry Gunther, Selma Edelman, Debby Hindman.
- Music: Gary Lionelli.
- First Aired on May 19, 1996.
- Originally Aired on Cartoon Network (USA).
- Running Time: 7 minutes.
- Season: 1
- Color
Cartoon Summary:
There's an evil Italian from outer space taking over Monkey's mind and interrupting his date with Agent Honeydew.
Cartoon Video:
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Do you love Orgon Grindor, or do you think it is the worst cartoon ever? Let us know what you think! Surely you have an opinion... so share what you think. Take a minute and post your own comments about this cartoon here.


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Choke Holds YKTTW Discussion
|Choke Holds
When Bob chokes Alice.
There are two kinds of chokes. Blood and air. The air choke is when someone is choked unconscious by cutting off his air supply. The air to the lungs is suspended. In fiction the person chokes and flails in silence, and after maybe thirty seconds he is rendered unconscious. In reality, cutting off someone's air supply would take several minutes and he'd be at full strength the whole time. Do not choke someone this way. The blood choke is when someone is choked unconscious by cutting off his blood. The supply of blood to the brain is suspended. In fiction the person goes cross-eyed and immediately succumbs to unconsciousness. In reality the, process takes a few seconds and the victim understands what's happening and can protest, in the brief window available. Do choke someone this way, if you know what you're doing. If you don't, you can kill someone. Sometimes a blood choke causes the collapse of the arteries carrying blood to the brain and, inevitably, death. This is why cops no longer employ "The Sleeper Hold". It kills. Compare Tap on the Head where unconsciousness is rendered with a blow. Also, the Vorpal Pillow, where a choke hold causes instant death. This is a choking trope.
Chokes in life and in fictionAnime
- In Street Fighter II V, Bison does this to Chun Li, in the midst of a psycho power-fueled rage, but nearly goes too far.
- Shinji chokes Asuka in Neon Genesis Evangelion?!
- Guy Ritchie's Sherlock Holmes features both chokes at the same time. A thug sneaking up on Holmes is put in a blood choke by Watson. To prevent the Mook from screaming, Holmes immediately pinches off his nose and mouth. They chat for a bit and, once the thug has passed out, move on. At the end of the film, a big mook has to be slowly air choked because he's just too darn big for anything else.
- Darth Vader's Force Choke appears to be a long distance mystical air choke. Slow, unpleasant, unstoppable. Very dark-sidey.
- Two chokes appear in Never Say Never Again. James uses a sleeper hold on a Mook guard during Unwinnable Training Simulation opening and an assassin uses a sleeper hold on one of the attendants at Shrublands.
- In The Princess Bride, The Man in Black knocks out Fezzik with a blood choke. It takes several minutes and they have a rather cordial conversation all the while.
- In Sneakers Dick Gordon knocks out Bishop with a sleeper hold. In contrast to the repeated Tap on the Head he's been given up to this point, it's an act of mercy.
- In The Bishop's Heir, Dhugal (who doesn't then know he's Deryni, never mind controlling his shields) reacts badly to the psychic energies unleashed at Duncan's consecration as bishop. Morgan uses a choke hold on Dhugal to get him away from the cathedral via Transfer Portal and avoid unwanted attention from potentially hostile clerics when Dhugal's shields prove impossible for Morgan to breach.
- A form of the "sleeper hold" variant comes up in Yoda: Dark Rendezvous. Weak, but Skilled Padawan Scout has a particular move where she can grab someone's throat, cut off the blood flow, and render them unconscious in seconds without permanently damaging them. She uses it in Padawan tournaments to great effect.
- Burn Notice's Michael Westen is adept at the blood choke. His victims rarely cry out, but they rarely have time.
- Law & Order features a victim of a fatal blood choke. A military man upset at a Jerk Pacifist mocking his dead son employs a sleeper hold blood choke. It leaves telltale bruises over the victim's carotid arteries.
- Subverted by Angel. Someone tries to air choke the titular character only to learn, to his dismay, that that doesn't work on vampires.
- While Dexter prefers to sedate his targets, he's been known to strangle them into unconsciousness. Acceptable, considering what he plans to do with them doesn't really require them to be in the best health anyway. His brother was considerably more fond of the sleeper hold, although his goals were basically the same.
- In an episode of NCIS, a sleeper hold accidentally kills someone.
- This is a standard (if illegal) move.
- Deus Ex: Human Revolution - one of the non-lethal takedowns.
- Metal Gear Solid. Snake can sneak up on guards, grab them by the neck, and throttle them unconscious. When they wake up, they're perfectly fine. Handled slightly realistically in that Snake can kill a guard by throttling him until his neck breaks. In MGS3, if guards are hungry and weak, Snake can instantly knock them out with an Unnecessary Combat Roll.
- After beating Sniper Wolf for the first time, Snake himself got knocked out this way though.
- Jonny Quest TOS episodes, "The Quetong Missile Mystery", Race Bannon uses a sleeper hold on a Mook guard.
- Blood chokes are part and parcel of martial arts and MMA. If an MMA fighter taps out half a second after an arm goes 'round his neck, it's because he's about to pass out.
Replies: 14


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You Have Until February 27th To Apply To Get Google Glass (Must Apply Using Google+ Or Twitter)
|3 years ago
|class of '04 - away - #1
7295 pageviews
70 comments
Youve probably heard some of the buzz about Google Glass, the pair of glasses with a built-in heads up display and camera. While its not yet available for the public to buy, itll be a reality before you know it. In the meantime, check out this demo video of Google Glass in action.
[pic - click to view]
Googles recently released Google Glass video makes the new product look very exciting. Recently, Google started the #ifihadglass campaign, a campaign to determine which people should be the first to test out Google Glass. Applicants must participate on Twitter or Google+. Additionally, it appears that Google is looking for creative uses of the product, as applications can include photos and a video. Its worth noting that if selected, you must purchase a Glass Explorer Edition for $1,500 and travel to New York, San Francisco, or Los Angeles for an in person pick-up. More details are below, or you can click here for all the information.
Using Google+ or Twitter, tell us what you would do if you had Glass, starting with the hashtag #ifihadglass.
Your application must be 50 words or less
You must include #ifihadglass in your application
You can include up to 5 photos with your application
You can include a short video (15 secs max)
Be sure to follow us on Google+ (+ProjectGlass) or Twitter (@projectglass) so that we can contact you directly
You must be at least 18 years old and live in the U.S. to apply
For more details, please see our full Terms and FAQ
Last edited by Da Ill One; 02-20-2013 at 11:59 AM..
|3 years ago
|class of '04 - away - #10
It appears that Google borrowed from IBM's vision back in 2000. And now they created another game changer.
[pic - click to view]
[pic - click to view]
Last edited by marcchrome; 02-21-2013 at 01:00 AM..
|3 years ago
|class of '06 - away - #14
I dont like this sh*t. Not that it isn't amazing, because it is.
Plus my iPhone still can't understand my accent, bout to record myself jerking it, say "send it to Monica, and it'll prob get sent to mom"
[pic - click to view]
But the fact that someone can just record you anywhere and you have no idea....
|3 years ago
|class of '10 - away - #15
The life of a student or working professional is not even worth applying for these.
|3 years ago
|class of '12 - away - #16
Hold up... We have to pay you to test your project if were "lucky" enough to get chosen???
$1500 isnt a lot of money considering half the crap I spend money on but damn. It's a contest on who has the wealthiest and most adventuring life so most of the world is out of the drawing already!!!
|3 years ago
|class of '04 - away - #17


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Replacement Punch for Model 6880
This item is the replacement punch for Milwaukee's 10 gauge nibbler model 6880. The replacement die, 48-44-0275, is purchased separately. Must be used with Allen wrench 49-96-0350 to remove the punch or die.
- 10 Gauge
Since its founding in 1924, Milwaukee has focused on a single vision: To produce the best heavy-duty electric power tools and accessories available to the professional user. Today, the Milwaukee name stands for the highest quality, durable and reliable professional tools money can buy.
Additional Milwaukee Links
This Milwaukee item can also be referenced by the following color/finish specific model #:
- Milwaukee 48-44-0265
10 Gauge
*Discontinued model or finish
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Discover the best online deals for the 48-44-0265 and everything else for your home from the leading online home improvement store.
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Whether you are installing the product yourself or hiring a professional, our installation Resource Center has everything you need to get your project done. Visit the Installation Resource Center to get started.


text: TGH Writes: "It's rare to come across a game that has me grinning from ear to ear from beginning to end, but this is exactly what Thomas Was Alone caused me to do. Let me be the first to say that I never thought a game like Thomas Was Alone would evoke such feelings. On the surface it's little more than a game where you simply control a bunch of rectangles through clever little levels. But deeper down it's a game all about imaginative and downright excellent platforming. It's a game so simple in its core mechanic, yet so absolutely delightful to play that you'll remember it for a long time to come." 4.5/5


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Welcome to WebmasterWorld Guest from 18.104.22.168
Forum Moderators: open
Account Lockdown: Unusual Activity Detected
This account has been locked down due to unusual account activity. It may take up to 24 hours for you to regain access.
Second time in two days! I just sent an email to friend. Yesterday I was having pop/mx issues using outlook with gmail, which must have been the cause of this -- but it was corrected.
I think I'll start to reconsider how much I invest in google. They are getting slow, and I'm seeing them go down frequently.
[edited by: mona at 2:09 pm (utc) on Sep. 5, 2007]
[edit reason] language - thx! [/edit]
maybe you are sending emails from another account without realising that you are going through gmail
I think it might have started yesterday because I ignored the repeated Outlook error messages (for a few hours) whenever it tried to check my unactivated google-apps email. I was hesitating to switch over my MX records mid-week, and should have deleted the new Outlook email account.
They shut down my main personal gmail acct, and two business google-apps accts. Yesterday and today. What a drag, specially as it happened shortly after sending them $100 for the new apps acct.
I'll have to see if there is a problem with checking 2-3 accts at the same time with pop email. Hopefully not, I would like this to work as an alternative to microsoft exchange.
This confirms to me that G-apps is not suitable for business and I'm going to cancel my accounts. Many people on here have mentioned how they don't want to get too tied up with Google and have them knowing everything about their business etc. But I have always reasoned that I don't have anything to hide from them but now I see that you can't give the keys to your business to Google because they can just shut you down at any time. (not to mention the SERPs)
I'm glad I checked this out in baby steps. To begin my disentanglement from the Gorg, I have just switched my default search engine to MSN Livesearch. More to follow. Cheers


text:
Adams is an amazing storyteller with a gift for connecting with readers on many levels. Her well-crafted tale has much for readers to relate to, and wonderful spiritual truths that shine through the entire novel.
Dayna is pleased with the way her life is heading, and thinks a marriage proposal from her longtime boyfriend Warren may be soon approaching. Yet when her ex-husband Brent shows up on her doorstep, begging Dayna to have dinner with him and his wife Tamara (the woman who Brent cheated on Dayna with and then married), Dayna just wants to scream and run the other way. His persistence makes her finally give in and the news he delivers stretches the faith and devotion of everyone involved. (ZONDERVAN, Feb., 320 pp., $14.99)
Reviewed by:
Melissa Parcel


text:
Two supercomputers dedicated to life science research — both from Japan — have joined the ranks of the world's fastest supercomputers, according to the twice-yearly Top500 list released earlier this month.
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In PNAS this week: researchers identify the characteristic genomic features of clear cell renal cell carcinoma, and more.
A technology that has the potential to make species go extinct could be used against the Zika virus.
University of the Republic postdoc Victor Morais says researchers should be careful of the open access journals they choose to publish in.
If science funding agencies can talk tough about sexual harassers, shouldn't they also put their talk into action?
This webinar will demonstrate how ACMG's recommended variant scoring and classification rules may be applied to standardize reporting on sequencing test results within and across institutions.
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text: We eat cranberry sauce but once a year, so why shouldn\u2019t it get the homemade treatment, too? We tested canned versus homemade jellied cranberry sauce to find out if the effort is really worth it. Fake It or Make It? Green beans, cream of mushroom soup, and french-fried onions make a simple, crowd-pleasing side dish. But is the now-classic combo ready for a from-scratch upgrade? Fake It or Make It? No Thanksgiving table would be complete without the savory, buttery, carb-filled side dish. We see how the just-add-water-and-margarine version stacks up against a recipe of our own. Fake It or Make It? Heritage turkeys (naturally-raised historic breeds) might be a more sustainable (and more expensive) option for the Thanksgiving table, but do they taste better than the conventional bird? Fake It or Make It? When it comes to pumpkin pie, canned puree makes for easy assembly (canned pumpkin pie mix even easier!), but does it sacrifice the flavor and quality that freshly pureed pumpkin provides? Fake It or Make It?


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pwing's review on 9/14/2005
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Mark Ashley's Double Play 2 by Digital Sin Performers: Cytherea, Tiana Lynn, Avy Lee Roth, Rio, Jada Fire, Vanessa Blue, Vanessa Lane, Kat, Hilary Scott, Mya Mason, Mark Ashley, Mr. Pete, Joachim Kessef Extras: BTS, bonus scene, gallery, trailers, web trailer, company info. Scene One: Cytherea, Tiana Lynn, Mark Ashley If you're a fan of girls who squirt then this scene is required viewing. Tiana and Cytherea do a great job of sucking cock in tandem. Tiana get bonus points for her smoldering eye contact which seems to say either "I'll eat you alive" or "I'm ready for war" I'm not sure which. Tiana also turns out to be the wetter of the two here unloading amazing amounts of fluid multiple times throughout the scene. Scene Two: Avy Lee Roth, Rio, Joachim Kessef Both of these girls gag themselves on cock at the beginning of this one. Fans of sloppy BJ's should like this one. The sex quickly escalates when Rio gets stacked atop Roth's back allowing Kessef easy access to both pussies.
picman's review on 11/27/2004
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Prologue I remember a Beach Boy's song that began with the refrain: "Two girls for every boy." It's every man's dream. Mark Ashley has devoted a series to the concept and this is it. And some of these pairings look to be smoking. Tiana Lynn and Cytherea. Get out the raincoats! Vanessa Blue and Jada Fire! If it's half as good as their scene together in Ass Worship 6 it'll be memorable. Let's get ready to rumble. Cytherea and Tianna Lynn are lounging around in the house playing with themselves. Cytherea is using some kind of vibrator and rummaging around inside her panties. Tianna comes over and takes over, pulling off her panties and getting down for some carpet munching and fingering. We all know what cums of this as Cytherea's body spasms almost immediately. Mark Ashley joins them before things get too heated. He helps out with Cytherea. Cut to the girls teaming up on Mark's stiffy and everybody's laundry getting dropped. Tianna is the first to get fucked, in mish. She's gushing in no time at all and Cytherea does P2M.


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Category Archives: Levana Kirschenbaum
My Passover Kitchen Diaries: Anatomy of a Week in the Home Kitchen Trenches
When it comes to my Passover Kitchen, I mean Kitchen Diaries, Anatomy and Kitchen Trenches quite literally. Let me start by saying that ALL my Passover Recipes are included in this link, ALL Non-Gebroks I have been asked countless times by fans, family and friends the perennial Passover Kitchen question: "How...
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Filed under: Kollel Store, Kosher for Passover Recipes, Levana Kirschenbaum, Passover Holidays, Passover Kitchen, Passover Planning, Passover Recipes, Recipes, Stories, Whole Foods Cookbook, Whole Foods Kosher Kitchen
Moroccan Almond Cookies Recipe. Ghriba. Vegan.
These Moroccan Almond Cookies are a great Moroccan/Sephardi favorite, called ghriba. Traditionally we make them round and top them with a little cinnamon. I am including the Traditional Basic Ghriba recipe here as well, so this Moroccan Almond Cookies variation, although it takes some poetic license, is a welcome change of pace,...
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Filed under: Almond Recipes, Cookie Recipes, Dairy-Free Dessert Recipes, Dairy-Free Recipes, Dessert Recipes, Gluten Free Recipes, Gluten-free Cookie Recipes, Gluten-Free Dessert Recipes, Levana Kirschenbaum, Moroccan Dessert Recipes, Moroccan Recipes, Recipes, Sephardi Recipes, Vegan Desserts Recipes, Whole Foods Cookbook, Whole Foods Kosher Kitchen
Moroccan Chickpea Soup Recipe
Chickpea soup is much dreamier than – and nowhere near as plebeian as – it sounds. Especially when you make chickpea soup, as I do, with all our wonderful Moroccan seasonings. The French term for chickpea is "pois chiches," meaning something like pea's poor relatives. Wow, if poor and modest...
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Filed under: Chickpeas Recipes, Gluten Free Recipes, Jewish Recipes, Levana Kirschenbaum, Moroccan Soup Recipes, Recipes, Sephardi Recipes, Soup Recipes, Vegetarian Soup Recipes, Whole Foods Cookbook, Whole Foods Kosher Kitchen
Upcoming Cooking Demo in NYC. Monday March 19th: Seder Feast
Here's a feast you won't spend days knocking yourself out preparing: Even the stunning fish terrine is much easier to make than it sounds! I'll be demonstrating: Wild mushroom soup Tricolor fish terrine with watercress sauce Mixed greens with walnut dressing Roast beef shoulder with root vegetables Individual potato kugels...
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Filed under: Cooking Demos Gift Certificates, Kosher Cookbooks, Kosher Cooking Classes, Kosher Cooking Demos, Kosher Cooking Demos in New York City, Levana Kirschenbaum
Warm Fig Tart Recipe. Gluten-Free Friendly
A nice and super healthy take on pumpkin pie, and so easy to make. Easily converted to a gluten-free treat: You could use any flour at all. The pairing of figs with rosemary is deliciously funky. Remember, as always: No cooking wine or cooking sherry or any of those calamitous...
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Filed under: Dairy-Free Dessert Recipes, Dessert Recipes, Figs Recipes, Gluten Free Recipes, Gluten-Free Dessert Recipes, Gluten-free Pie Recipes, Kosher Natural Foods, Kosher Recipes, Kosher Whole Foods Recipes, Levana Kirschenbaum, Low-Carb Recipes, Pareve Recipes, Recipes, Spelt Baking, Whole Foods Kosher Kitchen
Upcoming Cooking Demo in NYC: Monday March 12. Biblical Feast
I got the inspiration for this wonderful meal some years ago during a fascinating visit to Naot Kiddumim, near Jerusalem, where everything that was used to grow and harvest the "Sheva Minim" (olives, pomegranates, figs, grapes, dates, barley and wheat) is still intact, just as in the ancient days when...
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Filed under: Cooking Demos Gift Certificates, Kosher Cookbooks, Kosher Cooking Classes, Kosher Cooking Demos, Kosher Cooking Demos in New York City, Levana, Levana Kirschenbaum, Natural and Kosher Recipes
Upcoming Cooking Demo in NYC: Monday February 20th:
No time to cook? All the more reason to learn how to whip up sensible and delicious meals in good health in a jiffy! Here come not one but two perfect meals, complete with delicious desserts, prepared in minutes. After years of cooking up a storm, the quick-and-healthy theme emerges...
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Filed under: Cooking Demos Gift Certificates, Kosher Cooking Classes, Kosher Cooking Demos, Kosher Cooking Demos in New York City, Levana, Levana Kirschenbaum
Cooking with Levana: The Trust Game
The Trust Game Only a wonderful friend like Sherry at the Kosher Scene would go to the trouble of providing an elaborate, thoughtful and generous definition for a phrase. She had mentioned to me that making my recipes is just like playing the trust game, and when I asked her...
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Filed under: Levana Kirschenbaum, THe Kosher Scene, Trust Game
Kosherfest 2011!
Would it make me sound like a dinosaur if I said I remember early Kosherfest shows taking place, ages ago, with flocks of young mothers pushing strollers and turning the show into a giant lunch break in an industrial playground? Then the show moved to Javitz Center sans strollers, then...
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Filed under: Chocolate Bark Recipes, Chocolate Recipes, Dairy-Free Frozen Dessert Recipes, Dairy-Free Recipes, Gluten Free Recipes, Jack's Gourmet Sausage Recipes, Kosher Cheeses, Kosher Cookbooks, Kosher Ice Cream, Kosher Ingredients, Kosher Natural Foods, Kosher Recipes, Kosher Whole Foods Recipes, Levana Kirschenbaum, Natural Kosher Cheeses Recipes, Pardes Restaurant, Stories, THe Kosher Scene
Review of my Cookbook by Tara Barker
Thank you so much Tara Barker for your glowing review of my Latest Cookbook! Cookbooks these days have become works of art. We display them on our coffee tables, give them our coveted, valuable kitchen counter space, we read them in bed as if they were gripping novels. Their pages...
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Filed under: Cookbook Reviews, Gluten Free Recipes, Levana Kirschenbaum, Passover Recipes, Spelt Baking, Tara Barker, Whole Foods Kosher Kitchen


text:
Kitty by KiddAtsumaWatch
©2012-2016 KiddAtsuma
:3 have fun dying from cutness
cute kitty is cute
AWWWWWWWWWW!!! *exploded*
Those eyes
yes cute cat lol
This is Taylor Swift's cat!!! Meredith!!! I love her!!!
this is so true ^^
aww.. how cute, i love cats!
Awww so cute! <3
dying from the cuteness
But I'm allergic to cats! D:
.................hmmmm do say that cute...............too cute..........*fwoosh*........hmm my eye seem to ignited from the cuteness................*inhale* ahem arrrgh it buuuuuunrnsss
I'm sorry, but even if the caption is yours, it's copyright infringement if you use a picture you don't own.
Look as long I'm not trying to make a profit off of everything is cool. If I was selling this then it would be bad but I'm not I created this for the sheer humor of saying that cats are cute and they what the caption on it says
I know your intentions are not bad, and I don't want to be mean to you or anything. I'm just saying it's against deviantArt rules. There are lots of others sites where you can share your works without troubles.
well not to be an ass you could have just left this alone really
Why? You're the one posting things against the rules.
I'm just doing the right thing letting you know.
I'm just doing the right thing letting you know.
The question is are you an admin on this site? or is this your pic? hmm?
I don't have to be an admin or the owner of this pic
This site is a community, and it can only work if -all- members respect each other.
This site is a community, and it can only work if -all- members respect each other.
You saying that like I don't respect other people which I do ask any of the people on my watch list and you will see that I do but the way your saying it is like I'm being rude to you when I'm not all I said was that you didn't have to post a comment to begin with and this whole incident could have been avoided.
Ohmaiguuurd so cuuuuute >w<
Those eyes, they are just.
kyaaaaaa**** so cute
no I can't wait to get home and hug my kitties
kyaaaaaa**** so cute
no I can't wait to get home and hug my kitties
Those eyes......


text:
Sydney Long-Sleeve V-Neck Dress
Original: $398.00 NOW: $159.20 This item is Final Sale.
See Promotion Details
*Offer valid through February 14, 2016 at 11:59pm PST. Receive an additional 30% off all Factory dresses at BCBGMAXAZRIA Factory locations in the U.S. and at http://www.bcbg.com/en/factory/dresses/. Only valid on orders shipping within the U.S. and select countries. Excludes BCBGMAXAZRIA Runway and Hervé Léger by Max Azria. Offer not valid on previous purchases or toward the purchase of gift certificates. Cannot be combined with any other coupon, offer or promotion. Discount taken at checkout. Not redeemable for cash. Online Factory purchases are final sale and may not be returned or exchanged online. Full value of discount forfeited upon return in-store. Additional exclusions may apply. BCBGMAXAZRIA reserves the right to modify or cancel this promotion at any time without notice.
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Additional Information
A versatile dress that flatters the figure and offers the perfect pop of color for any-season styling.
- V-neck. Long sleeves.
- Allover piping tape detail seams. A-line skirt.
- Exposed center back zipper closure.
- Rayon, Nylon, Spandex.
- Machine Wash.
- Imported.
- Measures approximately 35" from shoulder to hem.


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I had beans and rice. Also potatoes and squash. I'm stuffed.
What did you have?
Best Answer
Best Answer
No, I didn't know that. I'll alert the media!
Best Answer
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KABC/790 AM's morning drive personality Doug McIntyre is exiting morning drive after Thursday's program. Starting Friday, he will be replaced by Peter Tilden from 5 to 10 a.m.
"Doug is going to do mornings on WABC in New York starting immediately," said KABC program Director David G. Hall. "And we're starting efforts to find ways to resurrect the hugely successful Red Eye Radio he did overnights for us," he said.
McIntyre's Red Eye Radio enjoyed a short revival recently after Friday night Dodger games and the show received positive feedback.
Plans called for McIntyre to fly to New York immediately where he will do the 5 a.m. hour on WABC leading into the Don Imus program. Eventually he may do that one-hour for WABC from the KABC studios in Los Angeles.
Tilden has done morning drive, working with Ken Minyard in the late '90s, but this will be his first solo run. Tilden also did overnights but was laid off in 2008. He came back to occasionally fill in for Al Rantel earlier this year.


text:
Web 2.0: Pottymouth 1.0 Sanitizes User Input
Version 1.0 of Pottymouth, a Python module for HTML processsing has just been released. The tool helps sanitize user input from websites.
The mathematician and linguist Matt Chisholm designed the tool for any scenario in which untrained or untrusted users are allowed to enter HTML code or text: blogs, forums, web mailers, Web 2.0 applications and the like. Pottymouth sanitizes anything that could endanger the layout or security of a web application.
For example, the Python module prevents users from injecting Javascript via Iframe or script tags, event handler attributes or "javascript:" links, thus preventing scripting and cross site scripting attacks on websites and their users. Pottymouth attempts to protect the site layout by removing style tags, CSS input, and attributes such as "height" and "width". At the same time, it converts markups indicated in plain text ("*bold*") or lists into correct HTML and adds an HTTP prefix to "www" links
A source code archive, Debian and RPM packages of version 1.0 are available under the BSD license from the Pottymouth homepage, as is an online demonstration for potential users to test.
Issue 184/2016
Buy this issue as a PDF
Linux Foundation Eliminates Individual Membership
But you can still be a non-voting "individual supporter" if you pay the money
Secret Backdoor Affects More Fortinet Firewalls
Several current systems could fall victim to the attack
Linus Announces Linux Kernel 4.4
Latest Linux engine comes with better graphics and support for Intel's new power-saving chips.
Mass Poem Greets Web Admins
Hackers send a message of beauty and liberation to server logs
Raspberry Pi Becomes a Thin Client
Citrix gets excited about new Pi-Powered XenDesktop client system
Microsoft Offers Linux Certification
Linux on Azure cert heralds a new era for Redmond.
CeBIT 2016: Call for Open Source Contributions
Proposals for presentations at the CeBIT Open Source Forum will be accepted through 24 January 2016.
Gone in a Flash
Adobe looks for a new start; renames its embattled Flash tool.
Rasp Pi Generates Weak SSH Keys
The Pi's popular Raspbian OS pursues secrecy without entropy.
Photon Controller Goes Open Source
VMware bids for a stake in the container industry with a bold effort to integrate containers with its classic virtualization system.


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Announcing Cotton Spandex Jersey!
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The Open Dentistry Journal, 2008, 2, 67-72 67 1874-2106/08 2008 Bentham Open Open Access An In Vivo Model for Short-Term Evaluation of the Implantation Effects of Biomolecules or Stem Cells in the Dental Pulp Sally Lacerda-Pinheiro1, Arnaud Marchadier2, Patricio Donãs3, Dominique Septier3, Laurent Benhamou2, Odile Kellermann1, Michel Goldberg3,* and Anne Poliard1 1Laboratoire de Différenciation Cellulaire, Cellules Souches et Prions, IFR- 2937 CNRS, Villejuif, France; 2Laboratoire de Caractérisation du Tissue Osseux par Imagerie, INSERM U658, Orléans, France and 3Laboratoire Régénération et Réparation des Tissus Cranio-faciaux, EA2496, Faculté de Chirurgie Dentaire, Université Paris - Descartes, Mon-trouge, France Abstract: The continuously growing rodent incisor is a widely used model to investigate odontogenesis and mineralized tissue formation. This study focused on evaluating the mouse mandibular incisor as an experimental biological tool for analyzing in vivo the capacity of odontoblast-like progenitors or bioactive molecules to contribute to reparative dentino-genesis. We describe here a surgical procedure allowing direct access to the forming part of the incisor dental pulp Amelogenin peptide A+4 adsorbed on agarose beads, or dental pulp progenitor cells were implanted in the pulp following this procedure. After 10 days A+4 induced the formation of an osteodentin occluding almost the totality of the pulp com-partment. Implantation of progenitor cells leads to formation of islets of osteodentin-like structures located centrally in the pulp. These pilot studies validate the incisor as an experimental model to test the capacity of progenitor cells or bioactive molecules to induce the formation of reparative dentin. Key Words: Mouse incisor, dental pulp progenitor cells, amelogenin, experimental model. INTRODUCTION the central part of the pulp to the periphery of the embryonic pulp where the last cell division occurs [1]. When one of the daughter cells comes in contact with the basement membrane (BM) the cell becomes an odontoblast, whereas the other daughter cell located some distance away from the BM is incorporated in the Höehl's cell layer [2]. Odontoblasts and Höehl's cells constitute a specific subpopulation of neural crest-derived and paraxial derived mesenchymal-cells. After terminal differentiation they are responsible for dentin pro-duction (physiological and reactionary dentin). If the odon-toblasts are injured or destroyed during a carious lesion or its treatment, Höehl's cells may be reactivated and differentiate into new odontoblasts. Upon more severe injury, when the odontoblasts and Höehl's sub-odontoblastic cell layer are irreversibly destroyed, dentin formation can be mediated by odontoblast-like cells recruited among pulpal cells during the process known as reparative dentinogenesis [3]. However, it is well known that the natural capacity for healing of a tooth is limited and that therapies involving calcium hydroxide are not always successful. Therefore the search for strategies stimulating or mimicking the natural healing properties of the dental pulp is important. Two types of such therapeutic strategies can be conceived today depending on the severity of the lesions. Firstly, implantation of bioactive molecules used as new pulp capping agents that would accelerate and/or induce the formation of a bridge of reparative dentin [4]. Secondly, implantation in an exposed pulp of purified *Address correspondence to this author at the Faculté de Chirurgie Dentaire, 1 rue Maurice Arnoux , 92120, Montrouge, France; Tel: +33 158076808; Fax: +33 158076806; E-mail: firstname.lastname@example.com During dentinogenesis, pre-odontoblasts migrate from stem/progenitor cells that would promote the formation of a reparative dentin. Pulp implantation models have been developed over the years in different species [rat, rabbit, ferret [5-7], monkey [8, 9], dog [10], essentially to evaluate the long-term effects of bioactive molecules used as pulp capping agents. Mouse models have never been described, very likely due to their small size and hence difficulties in manipulating their teeth. However, the recent development of stem cell research, with all the data collected on mouse systems, makes it important to have access to a kin model. The continuously erupting mandibular incisor has been extensively used to study the cellular and extracellular events involved in odontogenesis, because all the successive stages of development can be found in a single tooth, which exhib-its many similarities with human tooth formation [11, 12]. A niche of stem cells was identified in the apical end region (cervical loop) of continuously growing teeth [13-15]. In the rat incisor, some of the stem cells continuously differentiate into odontoblasts, becoming functional, mature, old and fi-nally degenerate [16]. Ever-growing teeth (hypselodont) such as the rodent incisors, maintain this function through a rich population of stem cells, whereas molars display limited growth (brachyodont) in rodents, and consequently have a reduced number of stem cells. Therefore, the murine incisors may provide a model to first dissect the cellular and molecu-lar events underlying the regenerative processes. In the present study, we have investigated whether the mouse mandibular incisor could be exploited as an experi-mental model for analyzing the potential of dental pulp pro-genitors cells or bioactive molecules to promote the forma-tion of reparative dentin. A surgical technique was devel-
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68 The Open Dentistry Journal, 2008, Volume 2 Lacerda-Pinheiro et al. oped to gain an easy access to the apical forming end of the incisor by a limited perforation and to make a pulp exposure. An amelogenin peptide (A+4), which has been shown to act as a signaling molecule [17-19], and a dental pulp-derived odontoblast progenitor clone (17IA4) [17], were implanted into the pulp to validate the efficiency of the surgical ap-proach. In both types of implantation, formation of a os-teodentin-like neodentin was observed. Our data thus point to the validity of the mouse incisor as a tool to evaluate the potential of different types of stem cells or biomolecules for reparative dentinogenesis. MATERIALS AND METHODS Animals (3 months old-25g) (Charles River - Lyon, FR) were used in these experiments. All experiments were performed under an institutionally approved protocol for animal research. Thirty lower incisors from 15 adults males C57Bl/6 mice Agarose Bead, Molecules and Cells Preparation Labs, Hercules, CA) were used as a carrier for bioactive molecules and to facilitate the localization of the implanta-tion sites. They were rinsed several times in PBS and dis-tributed into a 12 microwell plate (?10 beads/ wells) with or without (control beads) 2 ?g of A+4. The plate was then incubated for 24h at 37°C to allow complete adsorption of the proteins at the surface of the beads. Affi-gel agarose beads (75-150?m in diameter, Biorad embryonic (ED18) pulp and cultured as described [20]. Ap-proximately, 2.5 x 105 cells combined or not with the aga-rose beads were distributed in Eppendorf tubes and centri-fuged (1000 rpm / 1min) to form pellets which were thereaf-ter implanted in the incisor. 17IA4, an odontoblast progenitor clone was derived from Surgical Procedure toneal injection of a solution of ketamine 20% (Imal-gène®500, Bayer Pharma, Puteaux, Fr) and xylazine 5% (Rompun®2%, Merial, Lyon Fr) (10ml/kg). An incision of about 1cm long was made through the skin with fine scissors to access the subjacent muscle layer, along a theoretical line joining the auditory meatus and the lip commissure (Fig. 1A). The masseter muscle was incised along its longitudinal axis with a scalpel blade. The periosteum was scrapped with a curette and the bone surface was exposed between the pos-terior angle of mandible and the molars block, approximately 1mm above of the mandibular basal border. The point where the outer oblique line crosses the apical loop of incisor was selected as a site for the pulp exposure (Fig. 1B, 1C). A low-speed dental drill equipped with a round tungsten-carbide burr size 6 (Dentisply-Maillefer, Ballaigues, Switzerland) was used to create a hole through the bone and tooth 9 (Fig. 1D). The mice were divided into 5 groups of 3 animals each. They received group 1- agarose beads only, group 2- A+4 + agarose beads, group 3- 17IA4 cells + agarose beads (this group was performed as a control for cell implantation), group 4- 17IA4 cells alone, and group 5- sham (surgery without implantation). After implantation, the muscular layer was closed with one drop of cyanoacrylate and cutaneous At day 0, the animals were anesthetized with an intraperi-layer was sutured with Vicryl-Monocryl* 4-0 (Ethicon – Jonhson&Johnson, Piscataway, NJ, USA). All the animals received 10 mg/kg ketoprofen (Profenid, Paris, France) as analgesic immediately after surgery. The mice were killed 10 days after implantation by cervi-cal dislocation. Immediately after, the two hemi-mandibles were dissected out and fixed in a 4% paraformaldehyde solu-tion overnight at 4°C (Fig. 1E). Fig. (1). Surgical procedure for implantation in the incisor pulp. Incision was done along a theoretical line joining the auditory mea-tus and the lip commissure (A), bone exposure (B) and perforation (C). Cells or agarose beads were implanted (D) and the mandibles were dissected after 10 days (E). Arrow points to the perforation site. Micro-Scanner Analyzes micro-CT (Skyscan®, Kontich, Belgium). The radiographic projections (n = 413) were acquired at 70 kV and 90 ?A with a fixed exposure time of 4 seconds. Four frames were aver-aged for each rotation increment of 0.45° to increase the sig-nal to noise ratio. The acquisition time was 2 hours. One thousand slices were reconstructed with the manufacturer reconstruction software (NRecon, Skyscan®) based on a modified Feldkamp algorithm. The resulting 3D dataset con-tained 1024 x 1024 x 1000 3.12 ?m voxel elements. The 3D surface rendering of the mineralized tissues was made using the manufacturer visualization software (CtVol, Skyscan®) with a global threshold chosen halfway between grey level of soft tissues and hard tissues. The 3D grey level dataset The mandibles were scanned using a 1072 Skyscan® 6E D C
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An In Vivo Model for Short-Term Evaluation The Open Dentistry Journal, 2008, Volume 2 69 and the 3D surface rendering allowed evaluating the opacity and the spatial distribution of the dentin formed. Histological Procedures tion. After dehydration in graded ethanol, the tissues were embedded in Paraplast plus (Kendall, Mansfield, USA). Sag-ittal (7 μm) sections were collected on SuperFrost slides (Menzel-Glaser®, Braunschweig, Germany). The slides were dewaxed, rehydrated and stained either with hematoxylin-eosin or Masson's trichrome. The samples were demineralized, in 4.13% EDTA solu-RESULTS infection or tissue necrosis was detectable in the treated mandibles, and despite the surgery, the soft tissues were in-volved in a healing process. 17/18 incisors were implanted successfully. In the two control groups 1 and 5, implanted with agarose beads alone or after surgical preparation with-out any implantation, respectively reparative dentin forma-tion was limited to area located around the beads or occlud-ing the pulp exposure site (Fig. 2A, 2B). Implantation with A+4-soaked agarose beads (group 2) led to the formation of a diffuse mineralized structure within the pulp as evidenced by histological (Fig. 2C) and microscanner analysis (data not shown). The newly formed tissue is reminiscent of osteoden-Ten days after implantation, no inflammatory process, tin, since the cells were trapped into osteoblast-like structure. Implantation of the progenitors cells (17IA4), alone or in association with agarose beads (groups 3 and 4), also pro-moted, in both cases, the formation of islets of osteodentin-like structures in the pulp (Fig. 2D-F). To assess the degree of mineralization of the newly formed dentin, 3D analyses by X-ray microscanner of the hemimandibles were per-formed (Fig. 3A-C). The pulps of the control and sham groups were radiolucent (Fig. 3D, 3F). In contrast, those implanted with the progenitor cells (Fig. 3E, 3G) or the bio-active molecules (data not shown) displayed a radiopacity very similar to dentin or bone. The microscanner analysis allowed determining that 10 days after implantation, the zone of mineralized neodentin has extended within the pul-pal compartment over a distance of roughly 1milimeters. DISCUSSION Experimental Approach that allows a direct access to the pulp of the forming mouse incisor. As no vital organ is concerned, the animals recover promptly from the surgery and it is possible to evaluate the biological effects of implantations of cells or molecules over a period of 1 to10 days. Afterwards, endogenous aging proc-esses, and odontoblast and pulp degeneration [16, 21], may interfere with the biological reaction under investigation. We have developed an in vivo experimental approach Fig. (2). Formation of neodentin ten days after implantation of the A+4 peptide or 17IA4 dental pulp progenitor cells in the pulp. Control groups showed a limited formation of neodentin [11] around the beads (A) or occluding the pulp exposure site (B). Implantation of A+4 charged beads induced the formation of neodentin in the pulp compartment (C). Implantations of the 17IA4 cells with (D) or without agarose beads (E) induced also the formation of osteodentin-like structures (F). Pulp (p), dentin (d), enamel (e), alveolar bone [29]. Bar 200μm. A D C B E F b b nb e e e e e nd d d d nnnp p p p p p ap aaaan
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70 The Open Dentistry Journal, 2008, Volume 2 Lacerda-Pinheiro et al. Previous studies have used a similar surgical approach by drilling a cavity through the basal bone to gain access to the enamel organ of the rat incisor [22, 23]. Another surgical attempt to selectively target the odontogenic organ was de-scribed, using an osmotic minipump connected to a bony window overlying the apical end of the rat incisor [24]. These approaches were mainly aimed at studying the effect of pharmacologic agents on the formation of dental mineral-ized tissues. Our strategy was focused on gaining easy access to the dental pulp, without perturbation of the enamel organ and of the stem cells niche located at the apex of the incisor [13, 25]. The present results establish our method as a useful and reliable approach in evaluating the capability of progeni-tors cells or bioactive molecules of promoting dentin regen-eration or repair. The Control Groups present by itself a capacity of self-repair [6, 7, 26, 27]. Scaf-folds of gelatin, collagen, alginate or agarose beads have been used as carriers for molecules implanted in the exposed pulps and may not be completely biological [9, 28]. The con-trol groups did not display any reparative mineralization in the pulp, and showed only a limited amount of reparative dentin at the exposure site as expected. The rodent incisors as other pulpal implantation models, The Effects of the A+4 Implantations uct (A+4) has been identified as a molecule expressed by the odontoblasts. It appears to function as a signaling molecule [18, 19]. A+4 had been shown to promote chondrogenesis The small molecular weight amelogenin gene spice prod-and osteogenesis either in vitro or when implanted in ectopic sites [19, 29, 30]. When used as capping-agent in rat molars, A+4 induce the formation of a true dentinal bridge, occlud-ing the pulp exposure in 15 to 30 days [31]. After implanta-tion in the pulp of molars, A+4 stimulates the recruitment (commitment) of cells that proliferate and differentiate into osteo/odontoblast-like progenitors, which after terminal dif-ferentiation will form a reparative osteodentin-like structure. The bioactive potential of A+4 was confirmed in the present study in the incisor model since formation of a significant amount of neodentin is promoted by this peptide in the den-tal pulp. In this context, as a continuously growing tooth containing an identified stem cell niche , the incisor may constitute a sensitive tool, to study the early stages of the dentinal repair process promoted by the amelogenin peptide, namely the recruitment steps of the pulp progenitors. The Effects of the Progenitors Cells Implantations human dental pulp. Significant effort is devoted to determine their therapeutic potential. After ectopic transplantation (sub-lingual region, subcutaneous), they produced a bone or den-tin matrix [32-34]. However, up to now, no report provides data on the ability of these cells to directly contribute to re-parative dentin formation after direct implantation into an injured dental pulp. The experimental approach used here provides some hints that such would be the case. Indeed, implantation of the clonal progenitor cells, 17IA4, into the pulp leads to the production of a large amount of reparative-like dentin. In contrast to the diffuse dentin formed after A+4 implantation, the 17IA4 cells promote the formation of a Stem cells have been isolated and characterized in the Fig. (3). Micro-scanner analyzes of incisor implanted with the 17IA4 cells. The red block indicates the zone analyzed (A) and the asterisk (*) corresponds to the perforation site in the bone (B), and in the tooth (C). Ten days after implantation in the pulp, no mineralization was observed in the control group (D,F) in contrast, the 17IA4 group formed a large mineralized structure within the pulp (E,G). A B C D E F G * * * *
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An In Vivo Model for Short-Term Evaluation The Open Dentistry Journal, 2008, Volume 2 71 dentin mostly located in the central zone of the pulp. Mi-croscanner analysis confirms the histological data on neodentin formation further demonstrating the mineraliza-tion process and its extent within the pulpal compartment. The formation of neodentin in the pulp may be explained by either the 17IA4 cells differentiating toward an odonto/ osteoblast phenotype and forming a osteodentin-like struc-ture, or by these cells producing signals that stimulate the commitment, proliferation and differentiation of some resi-dent progenitors cells. These alternative hypotheses are now under evaluation and preliminary results suggest that the implanted progenitor cells are indeed capable of producing neodentin (data unpublished). of the mouse incisor model as a tool to obtain a better under-standing of the mechanisms of reparative dentin formation stimulated by biomolecules or cell implantations. Therefore, it should also allow the study of the efficiency of new thera-peutic agents that may be used as pulp capping agents. Fi-nally, our results of cell implantation in the pulp show the capacity of dental pulp progenitors of contributing to dentin formation in an injured tooth, paving the way for initiating studies on cell therapy approaches of dentin injuries. In conclusion, the data presented herein validate the use ACKNOWLEDGMENTS Lacerda-Pinheiro was supported by Coordenação de Aper-feiçoamento de Pessoal de Nivel Superior (CAPES), Brazil. This research was supported by Fondation de l'Avenir, l'Institut Français pour la Recherche Odontologique (IFRO) and an Inserm "Somatic Stem Cells Research Grant" (N°.CS0307). We thank Arthur Veis for his generous gift A+4. Sally REFERENCES [1] Ruch JV. Determinisms of odontogenesis. Revis Biol Celular 1987; 14: 1-99. Höehl E. Beitrag zur histologie der pulpa und des dentins. Arch Anat Physiol 1896; 32: 421-6. 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Root or crown: a developmental choice orchestrated by the differential regulation of the epithelial stem cell niche in the tooth of two rodent species. Development 2003; 130(6): 1049-57. Harada H, Toyono T, Toyoshima K, Yamasaki M, Itoh N, Kato S, et al. FGF10 maintains stem cell compartment in developing mouse incisors. Development 2002; 129(6): 1533-41. Takuma S, Nagai N. Ultrastructure of rat odontoblasts in various stages of their development and maturation. Arch Oral Biol 1971; 16(9): 993-1011. Lacerda-Pinheiro S, Jegat N, Septier D, et al. Early in vivo and in vitro effects of amelogenin gene splice products on pulp cells. Eur J Oral Sci 2006; 114 Suppl 1: 232-8; discussion 254-6, 381-2. Tompkins K, Alvares K, George A, Veis A. Two related low mo-lecular mass polypeptide isoforms of amelogenin have distinct ac-tivities in mouse tooth germ differentiation in vitro. J Bone Miner Res 2005; 20(2): 341-9. Veis A, Tompkins K, Alvares K, Wei K, Wang L, Wang XS, et al. 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J Histochem Cytochem 1999; 47(3): 323-6. Opsahl S, Septier D, Aubin I, et al. Is the lingual forming part of the incisor a structural entity? Evidences from the fragilitas ossium (fro/fro) mouse mutation and the TGFbeta1 overexpressing trans-genic strain. Arch Oral Biol 2005; 50(2): 279-86. Tziafas D, Kolokuris I, Alvanou A, Kaidoglou K. Short-term den-tinogenic response of dog dental pulp tissue after its induction by demineralized or native dentine, or predentine. Arch Oral Biol 1992; 37(2): 119-28. Nakashima M. The induction of reparative dentine in the amputated dental pulp of the dog by bone morphogenetic protein. Arch Oral Biol 1990; 35(7): 493-7. Goldberg M, Smith AJ. Cells And Extracellular Matrices Of Dentin And Pulp: A Biological Basis For Repair And Tissue Engineering. Crit Rev Oral Biol Med 2004; 15(1): 13-27. Nebgen DR, Inoue H, Sabsay B, Wei K, Ho CS, Veis A. Identifica-tion of the chondrogenic-inducing activity from bovine dentin (bCIA) as a low-molecular-mass amelogenin polypeptide. J Dent Res 1999; 78(9): 1484-94. Lacerda-Pinheiro S, Septier D, Tompkins K, Veis A, Goldberg M, Chardin H. Amelogenin gene splice products A+4 and A-4 im-planted in soft tissue determine the reorientation of CD45-positive cells to an osteo-chondrogenic lineage. J Biomed Mater Res A 2006; 79(4): 1015-22. Six N, Lasfargues JJ, Goldberg M. Differential repair responses in the coronal and radicular areas of the exposed rat molar pulp in-duced by recombinant human bone morphogenetic protein 7 (os-teogenic protein 1). Arch Oral Biol 2002; 47(3): 177-87. Ogawa R, Saito C, Jung HS, Ohshima H. Capacity of dental pulp differentiation after tooth transplantation. Cell Tissue Res 2006; 326(3): 715-24. [13] [14] [15] [16] [17] [18] [19] [20] [21] [22] [23] [24] [25] [26] [27] [28] [29] [30] [31] [32]
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72 The Open Dentistry Journal, 2008, Volume 2 Lacerda-Pinheiro et al. [33] Gronthos S, Mankani M, Brahim J, Robey PG, Shi S. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proc Natl Acad Sci U S A 2000; 97(25): 13625-30. [34] Gronthos S, Brahim J, Li W, et al. Stem cell properties of human dental pulp stem cells. J Dent Res 2002; 81(8): 531-5. Received: December 12, 2007 Accepted: March 27, 2008 © Lacerda-Pinheiro et al.; Licensee Bentham Open. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any me-dium, provided the original work is properly cited.


text:
Fever Ray
By Marc Hogan , March 30, 2009
Photo by Johan Renck
Yes, Karin Dreijer Andersson is a real person. Never mind how masks, goblin vocal effects, theatricality, and sheer seriousness of artistic vision can make that hard to imagine. Whether as one half of icy Swedish electropop duo the Knife, or now on her eponymous solo debut as Fever Ray, Andersson has accumulated an awesome and intimidating body of work. Videos by Andreas Nilsson and a reportedly in-the-works opera about Charles Darwin only boost the mystique. Yet speaking by phone from just outside Stockholm, Dreijer Andersson turns out to be easygoing and generous with laughter in a languid, thoughtful conversation. We discuss inspirations from Paul Wall to Phil Collins to Neurosis, the ways Fever Ray is different from the Knife, and how she does all that spooky stuff with her voice. For the creepier side, just come over sometime and I'll play you the interview tape at half speed. Shiver.
Pitchfork: You've had this kind of veil of secrecy over things with the Knife. Why lift that now?
Karin Dreijer Andersson: Umm... [long pause]. Yes? [laughs] I don't think the Knife, our goal was never to be secret. Everybody's telling us we never did any promo but we did like hundreds of interviews everywhere. And finally we did a tour. We think it's important to let the music stand for itself more than focusing on the artist or the person who is behind it. Music has the potential and the capability to create something much bigger... it has the capability to be completely free, to do anything. And I think you limit that idea when you put yourself in front of it, in a way. So, I don't think I'm doing that now, either, but I try to use myself more to go along with the music.
Pitchfork: Identity seems to be an important theme in your work, and you've mentioned before in some of those interviews about how changing your voice allows it to be different characters. With Fever Ray, should we take this as being more the "real" you? Or is this another set of characters-- another mask?
KDA: I think it's both. I think for me Fever Ray is a kind of mental character that has all these different kinds of voices and different kinds of shapes that it can transfer to. It is also a bit more personal than I have been working with the Knife, I think. Since it's only me, I mean. When I started playing in bands in like 1994, I was in a band with five people, and then I started to play with [brother] Olof [Dreijer], and we were only two, and now it's only myself. So I think I have been able to find out what I really really want to do myself, trying out ideas that I haven't been able to do before because you don't have to compromise when you work by yourself.
Pitchfork: Are there some of examples of ideas on the Fever Ray album that you might have had to compromise on with your previous groups?
KDA: The working process. You can decide totally how you want to work. And trying out everything that comes up without anybody interfering. That's very important. I go to the studio early in the morning and am there by myself for like eight hours or so, and then I go home. I think that the process has also been quite different.
Pitchfork: So how did this solo album come about? I mean, was it just you were going into the studio and you happened to be by yourself now because Olof has moved away?
KDA: When we got home from the U.S. shows we did in 2006, we both felt that we needed some time off from each other and we both really wanted to work on our own for a while. And so, no, I think it was quite natural sine we had been working for seven years by that time.
Pitchfork: When you said it's more personal: There's some pretty intense emotion in the lyrics. How much is this related to things happening in your own life?
KDA: It's me who has written it, so it must have come from somewhere. But I mean, music and art is about ideas, I think. Especially music. You have the freedom to work with your ideas and your dreams and your fantasies, which is quite hard to do in many other places.
Pitchfork: You've mentioned two somewhat different influences for this album. Dead Man by Jim Jarmusch, with its really good soundtrack by Neil Young. And then, different but also really good music, "Miami Vice". I'm curious about how those have influenced you on this album and what other inspirations you might have had.
KDA: One thing about "Miami Vice" which I really try to capture in music is the feeling of-- that feeling when you see those guys go away on a very fast boat with big engines in the night. It's like a music video in the episode, as they play loud music and drive the boat. That looks fantastic.
Pitchfork: You recorded most of this in your studio, which is south of Stockholm, for seven months. You used your computer, and some computer, and-- how did you put it all together?
KDA: Yeah, I have a computer [laughs]. I work in Ableton Live. I have mostly software synthesizers and software drum machines. I'm very lazy. I don't really like to plug in a lot of equipment and external boxes and everything. But I use the guitar a lot, yeah, with some software amplifiers, mostly, and yeah I recorded stuff but have cut it and sampled it, mostly. But I think it adds a certain organic feel to everything, which makes it a little bit warmer and more alive.
Pitchfork: You've mentioned other influences that often seem to be movies or TV shows, but when it comes to computer-based music are there any other artists or records that are an inspiration for you? Any other electronic artists?
KDA: Um, Phil Collins [laughs].
Pitchfork: He counts.
KDA: I listen a lot to "In the Air Tonight". I think it has a really beautiful sound of the vocals which I listen a lot to. And also this 80s band, Alphaville... the melodies. But I also listen to the screwed and chopped album by Paul Wall.
Pitchfork: Oh wow, that makes a lot of sense.
KDA: Yeah, I mean, I think, especially in the screwed and chopped versions I think it's so warm when they pitch it down, and I try to do something similar [laughs]. I mean, I listen to really different kinds of music, to just pick out the best is hard. And also this Anonymous album by Tomahawk. I don't know if they did it together with or it was inspired by Native American singing, and it came two years ago. And I think that album has really influenced me with my drums.
Pitchfork: No German techno?
KDA: I think I was a little tired of techno [laughs]. It was the only thing that Olof [would play]. I listen a lot more to hard rock and metal: Neurosis, High on Fire. Olof has never been into hard rock or metal. He was much more into jazz. So maybe I just like music to go somewhere else for a while.
Pitchfork: There were a couple of different producers who helped you on this album-- Christoffer Berg and Van Rivers & the Subliminal Kid. What did they bring to the music?
KDA: Nowadays, especially when you think of electronic music, it's like, the producer is mostly the one who makes the music or the beats and everything. But I am more, since I'm that old, when I started to make music the producer was just sitting in the back shouting and drinking beer. So I had done most of the recording, and the songs were written, when I contacted these guys. But I definitely needed help with finalizing the tracks. Van Rivers & the Subliminal Kid changed most of my programmed sound into analogue sound. They kept the programming of the beats and the arrangements but they just switched the sounds into a lot of things that they recorded themselves, as well. Which I think their tracks have a bit deeper sound and are more organic. Christoffer came up to my studio and sat down with the EQ filters and so on. But he also sent me small parts of things that he wanted me to put in the project. He sent me a file, like, "Here are some congas, put them at 1:35." So they're very different ways of working. And then we mixed, all four of us, in an analogue, old, vintage studio in Gothenburg. So I think the sound that makes, it holds it together.
Pitchfork: While we're talking about the sound and the recording, I'm sure you've been asked this question way too many times, but how do you achieve that effect on your vocals?
KDA: There are so many software programs that you can use. But I actually bought a physical machine, a TC-Helicon Live, which is very fun to use. But I also use the Steinberg VoiceMachine software plugin, which I think is also good. But with the Helicron machine, you can do like four harmonies at the same time, so I use it in "Concrete Walls".
Pitchfork: How are you planning to bring Fever Ray to life on the stage?
KDA: I'm working with Andreas Nilsson, who does the visual part of it. We're not really done yet. It will definitely be something very-- [laughs] oh, it's hard to tell. But I have a proper band, which is five people. That's the big difference.
Pitchfork: How connected do you feel to all the music coming out of Gothenburg, like the Tough Alliance, Studio, and Jens Lekman?
KDA: I have been living in Stockholm now for years, but I still have parents who live in Gothenburg, so I go there once in a while. I think it's some kind of mentality that Gothenburg, people from there, they hate all the people from Stockholm [laughs]. Because Stockholm is very, like, posh and uptight, and everything should be so luxurious and refurbished. And that's the part of Stockholm which I don't like either. But I live a bit outside of Stockholm and I almost never go into town. I can live anywhere, I think.
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text: Comments (2) + Add comment Comments (2) Featured doogiebear + 1164d ago Who cares? The game has been out for a while with tons of hours of footage already on the net. Why do useless articles like this get approved? #1 Agree(0) | Disagree(0) | Report | Reply jakmckratos + 1164d ago Because I haven't played it for 30+ hours or anything yet #2 Agree(0) | Disagree(0) | Report | Reply Add comment You need to be registered to add comments. Register here or login Username Password Remember Rules & guidelines Login