text: PF-9 (parkerized w/gray frame) Listed in category: Guns > Pistols > Kel-Tec Pistols > Pocket Pistol Type /UserImages/5511/999549644 3854512.jpg Item Details Condition: NIB Item #: 999549644 Caliber: 9mm Luger Location: FL Seller Stock #: 29239 SKU: Have one to sell? Sell Now! Sell it yourself, Ship it yourself, or use a GA DropOff Location! Classified Ad Details This listing is no longer available or has been sold. Price: $329.99 Login/Register to Buy Shipping: $25.00 Payment Methods: Return Policy: Only if Defective Seller Details (More items from Jays Guns and Accessories) Name: Jays Guns and Accessories Seller Since: May. 2001 User Level: Verified FFL Dealer: FFL Dealer Positive feedback: 99% View Seller Security Verification (What's this?) This seller has completed 4527 transactions Address has been verified and will be sent on request at completion of transaction Click here to request seller's GunsAmerica Verified Address Description Shipping and Payment Additional Information This new Kel-Tec PF-9 pistol fires the 9mm round. It has a 3" barrel with a parkerized slide and a gray frame. This semi-auto pistol has an under barrel rail. This pistol comes with one 7 round magazine, a hardcase, and a lock. See Description Trades Accepted: No


text:
United States Marshals Service Famous Marshals
A selection of articles related to united states marshals service famous marshals.
Original articles from our library related to the United States Marshals Service Famous Marshals. See Table of Contents for further available material (downloadable resources) on United States Marshals Service Famous Marshals.
- King James Bible: Numbers, Chapter 4
- Chapter 4 4:1 And the LORD spake unto Moses and unto Aaron, saying, 4:2 Take the sum of the sons of Kohath from among the sons of Levi, after their families, by the house of their fathers, 4:3 From thirty years old and upward even until fifty years old, all...
Old Testament >> Numbers
- Love and Clarity
- Literally any state of mind may be created or enhanced within. It is commonly assumed that our thoughts and feelings are difficult, if not impossible, to change at will. But this is not so. The meditator soon realizes that it is they who are primarily...
Mind >> Telepathy and Group Mind
- Manifesting World Enlightenment: Part 4
- There can be no doubt that the world situation today is grave. It is becoming increasingly apparent that the institutions, governments, and traditional methods of society, have little effectiveness in solving a collective crisis of global proportions. In this...
Mind >> World Mind
- Dealing With World Mind Effects Through Greater Self Mastery (GM5)
- At one time or another, we have all experienced occasions where other people in the same room began to have a heated argument. The psychic dissonance created at that time, produced in us symptoms of shakiness, nervousness, a scattered thought pattern or other...
Mind >> World Mind
- The Pagan Roots of Democracy
- I stepped into the voting booth with civic pride and religious inspiration. The pastors urged the congregation to renew America and vote for a good Christian man, Ronald Reagan. I voted a straight Republican ticket. Those godless Democrats were no better than...
Saga of Times Past >> History & Anthropology
- Manifesting World Enlightenment: Part 5
- All things in the universe have at their basis, one fundamental essence which governs their creation, destruction and on-going actions. That singular essence is consciousness, (also known by some as God, or the Unified Field). Everywhere in Nature does...
Mind >> World Mind
- Raising the World Mind (GM10-11)
- Part 1 | Part 2 Part 1 The wise live in accord with natural laws. It is they who understand that the laws of nature are much higher than the laws of man, because breaking them implies penalties far greater than a fine or prison sentence. When a person...
Mind >> World Mind
United States Marshals Service Famous Marshals is described in multiple online sources, as addition to our editors' articles, see section below for printable documents, United States Marshals Service Famous Marshals books and related discussion.
Suggested Pdf Resources
- The Marshals Service turns 215 - US Marshals
- United States Marshals Service. Sept. 24, 2004.
- www.usmarshals.gov
- African Americans in Law Enforcement Traveling
- Marshal Service, the accomplishment and contribution of other African. American Also in the exhibit is the famous deputy U.S.
- www.blackpoliceresource.com
- Visitors' Guide to the United States Court House Indianapolis
- Joined by our colleagues at the United States General Services Administration, who own and manage the The offices of the United States Marshal are also in the building. The Marshals . Arts style made popular in the.
- www.insd.uscourts.gov
- Large Jail Network
- Heather Lowry, Inspector, U.S. Marshals Service .
- static.nicic.gov
- "The Presidents' Men: Black United States Marshals in America." On
- Jan 10, 2011 American Presidential appointed U.S. Marshals, who served or serves in the oldest law and Cambodia," "Marshal Service Gets Record Number of Black .
- www.frontiersinternational.com
Suggested Web Resources
- United States Marshals Service - Wikipedia, the free encyclopedia
- The U.S. Marshals Service is the oldest law enforcement agency of the legendary heroes in the face of rampant lawlessness (see Famous Marshals, below).
- en.wikipedia.org
- History of the U.S. Marshal Service
- The U.S.
- www.legendsofamerica.com
- U.S. Marshals Service, History, Historical Federal Executions
- U.S. Marshals Service, History, Historical Federal Executions.
- www.justice.gov
- U.S. Marshals Service, History, Big League Cards
- In the mid 1990's the U.S. Marshals Service produced a series of 'sports cards' .
- www.usmarshals.gov
- U.S. Marshals Service, History, The Undefeated Rebel: U.S. Marshal
- U.S. Marshals Service, History, The Undefeated Rebel: U.
- www.usmarshals.gov
Great care has been taken to prepare the information on this page. Elements of the content come from factual and lexical knowledge databases, realmagick.com library and third-party sources. We appreciate your suggestions and comments on further improvements of the site.
United States Marshals Service Famous Marshals Topics
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A mix of vendors offering everything from flowers to baked goods with reasonable prices and quality stock. For three years I have filled my vegetable garden with plants purchased at the Empire State Plaza Farmers Market.
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Print off these fun activity sheets to learn all about the importance of good dental health! All of these activity sheets are in Adobe Acrobat PDF format.
Join in the fun and try all our Healthy Toothousand Dental Health Activity Sheets!
dentists who have volunteered to provide students with custom-made mouthguards for a discounted or nominal fee.
If you're not satisfied or have an issue with the treatment you received from your dentist, the MDS can help.
Utilize the MassHealth's network to find a provider near you.


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Professional Associations & Memberships•American Bar Association (Member)•American Board of Trial Advocates (Diplomate)•American Trial Lawyers Association (Member)•Arizona Association of Defense Counsel (Member)•Defense Research Institute (Member)•Federation of Defense and Corporate Counsel (Member)•American Trucking Association (Member)•Trucking Industry Defense Association (Board of Directors, 2001 to 2010)•USLAW Network (Board of Directors, 2007 to present)•Claims and Litigation Management Alliance (Member)•International Association of Defense Counsel (Member)•National Retail and Restaurant Defense Association (Member)
Civic/Community Associations•March of Dimes- WalkAmerica, Committee Chairman- Board of Directors, 1980 to 1990- Chairman of the Board, 1988 to 1990- Presidents Society- Awards Committee- Charter Member•National Football League (Referee, #85, 1990 to present)
Mr. Hochuli has been a Partner with Jones, Skelton & Hochuli since it was founded in 1983. During that time, he has tried well over 150 civil jury trials to verdict. Mr. Hochuli concentrates his practice on professional liability defense, products defense, retail defense and transportation defense. He is a member of the Federation of Defense and Corporate Counsel and is an advocate member of the American Board of Trial Advocates. He is also a member of the board of directors and executive committee of the US LAW Network. In his free time, Mr. Hochuli moonlights as a Referee in the National Football League. Civic/Community Associations•March of Dimes- Walk America, Committee Chairman- Board of Directors, 1980 to 1990- Chairman of the Board, 1988 to 1990 - Presidents Society - Awards Committee- Charter Member •National Football League (Referee, #85, 1990 to present) Professional Recognitions & Awards•Listed, Best Lawyers in America, Personal Injury Litigation - Defendants, 2003 - 2016•Listed, Southwest Super Lawyers, 2007 - Present•Listed Top 100 Lawyers in Arizona, Arizona Business Magazine, 2015•Rated, AV Preeminent 5.0 out of 5AV Preeminent and BV Distinguished are certification marks of Reed Elsevier Properties Inc., used in accordance with the Martindale-Hubbell certification procedures, standards and policies.


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Meetings are held on the 2nd and 4th Thursdays at 1 p.m.
Location: WEST-218
Future Business Leaders of America-Phi Beta Lambda, Inc. (FBLA-PBL) is the oldest and largest national organization for students preparing for careers in business. FBLA-PBL prepares students for the "real world" professional experiences. Members gain the competitive edge for college and career successes. More than a quarter of a million students participate in this dynamic leadership organization.
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Democratic senator Mark Warner of Virginia sent out a message on his Senate office's official Twitter account that claimed Republicans would blame this week's winter storms on Obamacare. Warner, who is up for reelection this year, deleted the message, though it remains recorded at Politiwoops, a website documenting deleted tweets from politicians.
"Just a matter of time: waiting for the @VA_GOP to claim this winter storm was caused by The Affordable Care Act. #Snowbamacare," wrote Senator Warner. According to Politiwoops, Warner deleted the tweet 26 seconds after it was posted. Warner followed up with a tweet, blaming the deleted message on "staff."
Oops. Staff #fail on a snow day. Removed as quickly as possible. Enjoy the rest of your snow day.— Mark Warner (@MarkWarner) February 13, 2014
The tweet came from Warner's official Senate Twitter account, not his campaign account.
The Republican party of Virginia, whose Twitter account was referenced in Warner's deleted message, has been responding by pointing out that Warner was one of the deciding votes on Obamacare. There do not appear to be any tweets from the Virginia GOP's account suggesting that the snow storm was, indeed, caused by the health care law.


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"My first language was shy. It's only by having been thrust into the limelight that I have learned to cope with my shyness."
Related quotes
"I cannot find language of sufficient energy to convey my sense of the sacredness of private integrity"
"The great enemy of clear language is insincerity. When there is a gap between one's real and one's declared aims, one turns, as it were, instinctively to long words and exhausted idioms, like a cuttlefish squirting out ink."


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I'd like to get FreeRTOS running on an MSP430 processor using Code Composer Essentials v3.1. I found an example of just this at http://www.westmorelandengineering.com/toc.htm. Specifically I'm working with FreeRTOS_Demo.zip, the top one. When I try to open it with CCE I get an error that the workspace "was not created by this version of Code Composer". So I tried to import the project and I get an error "The Managed Make project could not be read because of the following error: Project type com.ti.ccstudio.managedbuild.ui.programTargetID not found. Managed Make functionality will not be available for this project."
I'm wondering what my problem is and how I can get the project to build, or should I go about this a different way?


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Richard Petty Experience
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ABROOKOVER dice Jacques, Thank you so much for making this book for me. I love it! This was truly an experience I will never forget. Everyone that I have shown the book to is absolutely amazed. I have received a lot of compliments on it, and I always, always tell them that you are the one who took all of those awsome pictures and put the book together for me! Thanks again for all you've done! This will be something that I'll have forever! Amy
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My Driving Experience - John Publicado 20 de noviembre de 2011
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The Department of Defense announced July 25 the death of two Marines who were supporting Operation Enduring Freedom.
Lance Cpl. Jeremy S. Lasher, 27, of Oneida, and Cpl. Nicholas G. Xiarhos, 21, of Yarmouth Port, Mass., died July 23 of wounds suffered while supporting combat operations in Helmand province, Afghanistan, according to federal officials. They were assigned to the 2nd Battalion, 8th Marine Regiment, 2nd Marine Division, II Marine Expeditionary Force, Camp Lejeune, N.C.
Lasher's family was said to have travelled to Dover Air Force Base in Delaware to meet the plane with his casket. Also a Marine, Ryan Lasher was said to be at the base to escort the body of his brother home.
Lance Cpl. Lasher's wife, Andrea and 1-year-old son Caden have been living in North Carolina while Lasher was deployed.
Lasher's funeral arrangements were incomplete, though the Campbell-Dean Funeral Home on Main Street in Oneida will handle the service, according to the funeral home's confirmation on Sunday.
Lasher is the tenth serviceman from the Mohawk Valley to be killed in action since 2003. Thirteen servicemen including Lasher have died in action in the Middle East between July 17 and July 25, according to the Department of Defense casualty reports. Another soldier died during this period after suffering wounds in Helmand Province, Afghanistan, and later being transported to Washington for medical attention, according to DOD reports. The soldiers lost in battle served in different military branches including the U.S. Air Force, Army and Marines and were killed while serving in both Afghanistan and Iraq missions.
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Cards Against Humanity
|$25.00 & FREE Shipping on orders over $35. Details
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- Enter your model number above to make sure this fits.
- 550 cards (460 White cards and 90 Black cards)
- Over 13 duodecillion possible rounds (10^40) with 6 players
- Professionally printed on premium playing cards
- Includes game rules and alternate rules, shrink-wrapped in a custom box
- America's #1 gerbil coffin
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If you've never played Apples to Apples or Cards Against Humanity, let me fill you in on how CAH works. There are Black Cards and there are White Cards. At the start of each round, one chosen player (The Judge) will select a Black Card from the stack. On these cards will be a phrase or question that needs to be answered/completed. This is where white cards come in. Players have 10 White Cards, which they use to complete the Black Card's question(s)/blank(s). After each player (besides The Judge) has chosen the best White Card in their hand to go with the Black Card, all players turn their White Cards in to The Judge. From here, The Judge reviews the White Cards and decides his/her favorite pairing of the White and Black Cards. The player who played the Judge's chosen White Card gets a point (if that matters to your group) and the gameplay starts all over.
Let me give you an example with word-for-word examples of what you'll find on the Black and White cards.
1. The Judge plays a Black Card that says: "Life for the Native Americans was forever changed after the white man introduced them to ____________."
2. All players (exc. the Judge) choose a White Card.
3. After everyone has chosen their White Card, the Judge reviews the responses: "Smallpox Blankets", "Drinking Alone", "A Can of Whoop-Ass", and "Take-Backsies"
(Before you read these and think I'm an awful person, these are actual White Cards that I have seen played on the aforementioned Black Card)
4. The Judge chooses "Drinking Alone" and the player who picked this White Card wins the round.Read more ›
If you aren't a horrible person already, you will soon be. You will play Cards Against Humanity, and as others have said, you will be shocked, appalled, and worst of all, you will learn and adapt. You'll reach for your smartphone and search for terms you've drawn such as "The Übermensch", "Heteronormativity", and "The Three-Fifths Compromise". You will commit these and many other newly-learned words to memory.
And that's where it all comes crashing down.
At first, you might allow "front butt" to casually wander its way into a conversation here and there. As more of your subconscious fights to unleash the trauma, you'll find yourself uttering "nipple blades" and "mouth herpes" in the most unacceptable of times. You'll visit the Cards Against Humanity website and bomb them with suggestions for new cards like "Cutting the cheese at a funeral" and "Scissoring".
Soon, you will meet up with new people to inflict Cards Against Humanity upon them and they'll be hooked. You will receive random voicemails and texts, asking for another hit of that "8 oz. of sweet, Mexican black tar heroin", and you will comply, because you're just as hooked as they are. They'll bring new friends in to freshen up the game...you will feel a rush as the look of shame crosses their innocent eyes as they win a round by playing "Amputees" against your "White People Like _____".
"I was just throwing that card away!" they'll proclaim, but you know the sad truth.
You will buy the expansion pack. You will host parties where you play through every card in both boxes.Read more ›
Take the black card, read it aloud. Everyone fills in the answers from their white cards. Groans, laughter, ugh, etc. Judge chooses the winner, who then takes the black card. Get the right number of black cards, and you win! Just like Apples to Apples, but goes better with Tequila.
We play this with the kids and the grandparents. Yep. Age 18-75. They both end up looking up about the same number of items. Occasionally there is a little embarrassment as the 18 year old realizes gramma knows EXACTLY and ENTHUSIASTICALLY what she is talking about, and vice verse. There are no secrets in this game.
If you want to take it to a more disgusting level, which is certainly not appropriate for kids and grandparents (and CAH is?, hmmm, have I already fallen?) you can try one of the 3rd party expansions, like Crabs Adjust Humidity http://www.amazon.com/s/ref=nb_sb_noss_1?url=search-alias%3Dtoys-and-games&field-keywords=crabs%20adjust%20humidity&sprefix=crabs%2Ctoys-and-games.
There are also templates available on the web to make your own custom sets.
Hint: Use smile.amazon.com to purchase, and you may end up in one of the upper levels of h e l l instead of straight to the bottom. Remember, it's for the kids.
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Most Recent Customer Reviews
Cards Against Humanity is definitely the best game I've played in years! Everybody LOVES IT.Published 2 minutes ago by Amazon Customer
This is a great game to play with new and old friends. Even the super conservative people in your group will have fun.Published 12 minutes ago by Misty lay
Hilarious! Fun! Exciting game! Great for parties with friends and family! This game will keep you laughing for hours!Published 22 minutes ago by Emily
Great way to get to meet new people! Lets you know who they really are!Published 51 minutes ago by Evan Robertson
Just hilariously inappropriate and offensive, so buyer beware. The new favorite amongst our friends, although it's definitely not something we'd pull out around the family or with... Read morePublished 1 hour ago by samanthastevens
We love playing this game. We are always playing board games, but this was one that is tons of fun, if you have a sense of humor. The entire family plays. Read morePublished 3 hours ago by Becky


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"Ultraconservative Islamist protesters climbed the walls of the United States Embassy in Cairo on Tuesday and took down the American flag, replacing it with a black flag with an Islamic inscription to protest a movie attacking Islam's prophet, Muhammad."
Did President Obama demand that the Egyptian government provide assurances that our embassy would be protected?
In fact, Obama's crack foreign service issued an … apology.
He apologized for the presumed existence of a movie that no one on this planet (to my knowledge) has seen in its entirety.
Even if such a movie does exist, it's pretty certain U.S. Government had nothing to do with the mystery film, and thus had nothing to apologize for.
Finally, U.S. embassy in Cairo was attacked, stormed, and the U.S. flag was torn down by a bunch of crazy Egyptians emboldened by the Arab Spring.
Yet Barack Obama felt he needed to issue an apology.
For our Embassy having been attacked.
And our flag having been torn down, and torn apart.
On the anniversary of the September 11 attacks.
Even during the most heated days of the anti-war demonstrations of the 1960s I never got into a projectile sweat about someone setting an American flag afire on a street in Cleveland or Chicago.
The flag is a symbol of America. It is not a holy relic. The republic could and, and did, survive those silly protests.
But no one apologized to the flag burners for having caused them such angst that they felt it necessary to use up precious lighter fluid to set a flag on fire.
Yet, Obama apologized to the Egyptian rioters.
A link to the trailer for this movie is on the Secret Decoder Ring page.
It has all the production values of a Captain Video episode from 1954.
Nevertheless, Obama apologized.
According to CNN, Obama's Administration issued a statement saying that it;
"condemns the continuing efforts by misguided individuals to hurt the religious feelings of Muslims -- as we condemn efforts to offend believers of all religions."
America is apologizing for those who would "hurt the religious feelings of Muslims?"
Did Buddhists kill 3,000 Americans on September 11? How about Hindus? Or, Zoroastrians? Or any of the other 21 major faiths that exist on the Earth?
No. But Obama felt the need to apologize to the one religion against which we are waging war.
Rush Limbaugh defends Rubio's debate answer: He's absolutely right that Obama knows what he's doing | Allahpundit
Time for Team Hillary to break out the gender card for young liberal women who prefer Sanders | Allahpundit


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Your Shopping Cart is empty.
Give it purpose - fill it with water filters, air filters, refrigerator filters, and more.
The Filbur FC-3725 is the replacement filter for the Unicel C-4609 R.
Guaranteed to fit or your money back!
The Unicel C-4609 Comp Pool & Spa Filter- Coleco F-110 has an outer diameter of 4 3/4 inches, with a length of 8 inches. This Unicel pool filter has an open top with a diameter of 1 1/8 inches, and an open bottom with a diameter of 2 3/8 inches. This Unicel C-4609 filter contains 5 square feet of filter media.


text:
Stock 49 by Wintermoon-StockWatch
©2008-2016 Wintermoon-Stock
Photo: El Bosso
Model: Me
Model: Me
Rock Goddess !
perfect combination!!!
Fantastic Metal Queen
mm, cool pose. I really like the overall look. I'm adding this to my stock collection
wow you're SO hot
I wet my pants and I'm not even lesbian. This is awesome and hot in all its glory. Gorgeous Flying V, sexy chic <3
Gorgeous ^^
100% Hotness
this pictire a little out of fous and i cant use it but i can the other 2
this is a great picture and might i add you are gorgeous (same with that guitar, know how to play?)
Thanks so much No, i dont know how to play
jackson > all
nice pic there
nice pic there
WOW! I love it! And the guitar <3 My boyfriend plays, too.
One can only dream to be "that" guitar
GREAT Pic!
GREAT Pic!
Excellent portrait and expression... Looks stunning!
Love it! Especially the guitar and boots!
Jackson Guitar?
i wish it wasnt so blurry :/
but still great photo :]
but still great photo :]
I'd like this more if it wasn't so blurry.
Badass! I can't wait to mess with this picture- it will be epic! >:]
Very nice!! Do you play??


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SOC 100 Principles of SociologyCredit Hours: 3Prerequisite: Reading: Grade of C or better in RDG 091, an ACT Reading score of 18 or above, or an appropriate placement score. Writing: Grade of C or better in ENG 098, an ACT English score of 20, or an appropriate placement score.+
This course examines human society and the complex relationships that exist between individuals, groups and institutions. This examination will be facilitated by focusing on methods and theories used in analyzing and understanding changes taking place in contemporary society. (1.1) Fulfills the ECC/IAI General Education/Behavioral Sciences requirement. IAI Course Number: S7 900 Proficiency Credit Available Pass/No Credit Not Available
Elgin Community College • 1700 Spartan Drive • Elgin, IL 60123-7193 • Phone: 847-697-1000 • maps & directions


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Are you Zhicheng Lin?Claim your profile
Publications (16)45.03 Total impact
Article: Common Human 5′ Dopamine Transporter (SLC6A3) Haplotypes Yield Varying Expression Levels In Vivo[Show abstract] [Hide abstract]
ABSTRACT: 1. Individuals display significant differences in their levels of expression of the dopamine transporter (DAT; SLC6A3). These differences in DAT are strong candidates to contribute to individual differences in motor, mnemonic and reward functions. To identify "cis"-acting genetic mechanisms for these individual differences, we have sought variants in 5' aspects of the human DAT gene and identified the haplotypes that these variants define. 2. We report (i) significant relationships between 5' DAT haplotypes and human individual differences in ventral striatal DAT expression assessed in vivo using [(11)C] cocaine PET and (ii) apparent confirmation of these results in studies of DAT expression in postmortem striatum using [(3)H] carboxyflurotropane binding. 3. These observations support the idea that cis-acting variation in 5' aspects of the human DAT/SLC6A3 locus contributes to individual differences in levels of DAT expression in vivo. 5' DAT variation is thus a good candidate to contribute to individual differences in a number of human phenotypes.
- [Show abstract] [Hide abstract]
ABSTRACT: Recent aggregation of evidence for the roles of endogenous agonist and receptor systems that are mimicked or activated by cannabanoid ligands has provided a focus for work that has elucidated details of some of the multiple physiological roles and pharmacological functions that these systems play in brain and peripheral tissues. This chapter reviews some of the approaches to improved elucidation of these systems, with special focus on the human genes that encode cannabanoid receptors and the variants in these receptors that appear likely to contribute to human addiction vulnerabilities.
Article: Proline mutations induce negative-dosage effects on uptake velocity of the dopamine transporter[Show abstract] [Hide abstract]
ABSTRACT: Ala and Gly substitutions for Pro 101 (P101) located in transmembrane domain 2 of the dopamine transporter (DAT) abolished transport activity but did not disrupt plasma membrane expression. Due to the high conservation of P101 in all neurotransmitter transporters and the capability of Pro to add flexibility to helices, we hypothesized that P101 contributes to the dynamic feature of substrate translocation. To test this hypothesis, here we analysed transport activity for DAT mutants where this Pro was mutated into different amino acids, including Ser, Val, Leu and Phe. The transmembrane domain 2 helix of P101F, unlike the other mutants, was computationally predicted to have a Van der Waals energy threefold higher than the wild-type helix. P101F mutant expression was consistently disrupted in COS cells. Among all the other mutants that express normally, P101V, with a side-chain size close to that of Pro, restores the transport activity of P101A by sevenfold. Most importantly, P101V, P101L and P101S display negative-dosage effects on dopamine (DA) transport, i.e. the velocity-concentration curve for DA uptake does not show a plateau with increasing [DA] but rather peaks and then goes down. These data support the view that P101 of DAT plays an essential role in DA translocation.
Article: SLC18A2 promoter haplotypes and identification of a novel protective factor against alcoholism[Show abstract] [Hide abstract]
ABSTRACT: The vesicular monoamine transporter 2 (VMAT2, SLC18A2) takes up cytosolic monoamines into intracellular secretory vesicles, preventing their neurotoxicity in the cytosol and discharging them into extracellular space by exocytosis. It has been shown that one-copy deletion of the VMAT2 gene increases locomotion activity significantly in response to drug treatments and dopamine neuron death rate in response to neurotoxin treatments in knockout mice. Little is known about promoter polymorphisms and their influence on SLC18A2 promoter activity. We have re-sequenced a 17.4 kb DNA in the SLC18A2 promoter region for Caucasians and revealed 47 polymorphisms that confer 13 haplotypes. One of the haplotypes reaches a frequency as high as 65%, likely due to positive selection. In vitro analysis showed a 20% difference in promoter activity between two frequent haplotypes and identified some of the polymorphisms that influence promoter activity. Four haplotype-defining single nucleotide polymorphisms (hdSNPs) can define the frequent haplotypes and by genotyping these hdSNPs, we find that haplotypes with -14234G and -2504C of SLC18A2 promoter region represent a protective factor against alcoholism (P = 0.0038 by Fisher's exact tests). Therefore, SLC18A2 promoter haplotypes defined here create a foundation for transcriptional characterization of individuality and for association study on monoamine-related human diseases.
Article: The human serotonin receptor 2B: Coding region polymorphisms and association with vulnerability to illegal drug abuse[Show abstract] [Hide abstract]
ABSTRACT: 5-Hydroxytryptamine (serotonin) receptor 2B (HTR2B) is involved in brain development. Although expressed in the human brain, HTR2B has not been investigated much for its role in higher brain functions. Here we describe a genome-scan with 391 simple sequence repeat markers in 300 Caucasians, identifying HTR2B gene as a candidate for drug abuse vulnerability. From DNA re-sequencing of 110 subjects, we discovered three novel single nucleotide polymorphisms (SNPs), two of which confer a double-mutant of the receptor protein in a drug-abusing population. Arg6, a conserved basic residue, and the conserved acidic Glu42 are mutated simultaneously into Gly, termed R6G/E42G. Furthermore, this double-mutant tends to associate with drug abuse (P = 0.08 by chi2 test). The third SNP that is a synonymous mutation in the codon of Gln11 showed significant association with drug abuse (P = 0.0335 by Fisher's exact test). Our data are the first suggesting that HTR2B contributes to brain architecture and pathways that are involved in illegal drug reward.
- [Show abstract] [Hide abstract]
ABSTRACT: Following exocytotic release of the biogenic amine neurotransmitters, norepinephrine and dopamine, are removed from the synaptic cleft by the respective transporter, norepinephrine transporter (NET) and dopamine transporter (DAT) located on the plasma membrane. The catecholamine transporters are the molecular targets for psychoactive drugs as well as drugs of abuse such as cocaine and amphetamine and the Parkinsonism-inducing neurotoxin, MPP+. Nicotine regulates the transport of catecholamines and MPP+ and may exert self-medicating effects for depression, schizophrenia and attention deficit hyperactivity disorder, and neuroprotective effects against MPP+ through the regulation of the transporters. The availability of cDNAs of these transporters has permitted detailed pharmacological studies in heterologous expression systems for determining the mechanisms of action of nicotine on transporters. Moreover, functional analysis of the effect of single amino acid substitution suggests that specific residues in DAT molecules may play a significant role in interaction with MPP+ and cocaine, and thus would promise a development of novel drugs with diverse chemical structures.
Article: GBPI, a novel gastrointestinal- and brain-specific PP1-inhibitory protein, is activated by PKC and inactivated by PKA[Show abstract] [Hide abstract]
ABSTRACT: The activities of PP1 (protein phosphatase 1), a principal cellular phosphatase that reverses serine/threonine protein phosphorylation, can be altered by inhibitors whose activities are themselves regulated by phosphorylation. We now describe a novel PKC (protein kinase C)-dependent PP1 inhibitor, namely GBPI (gut and brain phosphatase inhibitor). The shorter mRNA that encodes this protein, GBPI-1, is expressed in brain, stomach, small intestine, colon and kidney, whereas a longer GBPI-2 splice variant mRNA is found in testis. Human GBPI-1 mRNA encodes a 145-amino-acid, 16.5 kDa protein with pI 7.92. GBPI contains a consensus PP1-binding motif at residues 21-25 and consensus sites for phosphorylation by enzymes, including PKC, PKA (protein kinase A or cAMP-dependent protein kinase) and casein kinase II. Recombinant GBPI-1-fusion protein inhibits PP1 activity with IC50=3 nM after phosphorylation by PKC. Phospho-GBPI can even enhance PP2A activity by >50% at submicromolar concentrations. Non-phosphorylated GBPI-1 is inactive in both assays. Each of the mutations in amino acids located in potential PP1-binding sequences, K21E+K22E and W25A, decrease the ability of GBPI-1 to inhibit PP1. Mutations in the potential PKC phosphoacceptor site T58E also dramatically decrease the ability of GBPI-1 to inhibit PP1. Interestingly, when PKC-phosphorylated GBPI-1 is further phosphorylated by PKA, it no longer inhibits PP1. Thus, GBPI-1 is well positioned to integrate PKC and PKA modulation of PP1 to regulate differentially protein phosphorylation patterns in brain and gut. GBPI, its closest family member CPI (PKC-potentiated PP1 inhibitor) and two other family members, kinase-enhanced phosphatase inhibitor and phosphatase holoenzyme inhibitor, probably modulate integrated control of protein phosphorylation states in these and other tissues.
Article: Uhl, G.R. & Lin, Z. The top 20 dopamine transporter mutants: structure-function relationships and cocaine actions. Eur. J. Pharmacol. 479, 71-82[Show abstract] [Hide abstract]
ABSTRACT: Our laboratory and others elucidated the primary amino acid sequences of the dopamine transporter (DAT) by cloning its cDNA and genomic sequences more than 12 years ago. Motivations for this work included the ideas that cocaine's interactions with DAT accounted for its rewarding properties and that selective inhibitors of DAT/cocaine interactions might thus provide good anticocaine medications. Such ideas supported interest in the detailed structure-function relationships of cocaine/DAT interactions, and in the construction and characterization of extensive series of site-directed DAT mutants. We can now select the most interesting 20 cocaine-analog selective mutations of the more than 100 single- and multiple amino acid substitution mutations that we have characterized. These mutants selectively reduce the affinities of the mutant DATs for cocaine analogs, but (absolutely or relatively) spare their affinities for dopamine. Several themes relevant to cocaine/DAT interactions emerge from these mutants. First, such mutations are found in a number of different DAT domains. Secondly, many but not all of these mutations lie in groups, near each other and near the same faces of presumably helical DAT transmembrane domains. Third, most are also conserved in the serotonin transporter (SERT), a transporter that is now strongly implicated in cocaine reward based on data from knockout mice. We discuss the results from these "top 20" mutants in light of the strengths and limitations of current DAT models and data from other studies. Taken together, these studies appear to indicate direct or indirect participation of several specific portions of DAT in selective recognition of cocaine analogs. These studies provide a strong basis for redirected studies aimed at producing dopamine- and serotonin-sparing cocaine antagonists that would represent combined DAT/SERT disinhibitors.
Article: Phosphatidylinositol 3-Kinase, Protein Kinase C, and MEK1/2 Kinase Regulation of Dopamine Transporters (DAT) Require N-terminal DAT Phosphoacceptor Sites[Show abstract] [Hide abstract]
ABSTRACT: The dopamine transporter (DAT) modulates dopamine neurotransmission and is a primary target for psychostimulant influences on locomotion and reward. Selective DAT expression by dopaminergic neurons has led to use of cocaine analog DAT radioligands to assess rates of progression of dopamine neuronal degeneration in Parkinson's disease. We have documented that DAT is a phosphoprotein that is regulated by phosphorylation through pathways that include protein kinase C cascades. We now extend this work using drugs selective for phosphatidylinositol 3-kinase (PI3K), protein kinase C, MEK1/2, p38 kinase, and Ca2+/calmodulin kinase II. We compare the drug effects on wild type DAT to the effects on 20 DAT mutants and a DAT deletion. PI3K and MEK1/2 modulators exert strong effects on DAT expression patterns and dopamine uptake Vmax. PKC principally modulates Vmax. Neither p38 nor Ca2+/calmodulin kinase II agents exert significant influences on wild type DAT. Several mutants and a DAT with an N-terminal deletion display alterations that interact with the effects of kinase modulators, especially S7A for PKC effects; T62A, S581A, and T612A for PI3K effects; and S12A and T595A mutants for MEK1/2 effects. 32P-Labeling studies confirm several of these effects of kinase pathway modulators on DAT phosphorylation. DAT expression and activities can be regulated by kinase cascades that require phosphoacceptor sites most concentrated in its N terminus. These results have a number of implications for DAT regulation and mandate caution in using DAT radioligand binding to infer changes in dopaminergic neuronal integrity after treatments that alter activities of these kinase pathways.
Article: Human dopamine transporter gene variation: Effects of protein coding variants V55A and V382A on expression and uptake activities. Pharmacogenomics J. 3:159-168[Show abstract] [Hide abstract]
ABSTRACT: The human dopamine transporter (DAT, SLC6A3) is an important 15 exon gene for dopamine neurotransmission and dopamine recycling. Common exon 15 variable number tandem repeat variants can be associated with attention deficit/hyperactivity disorder. Rarer single nucleotide polymorphisms produce missense variants including V55A and V382A. We now report studies of the functional influences of these DAT protein-coding variants. In COS cell transient-expression assays, V382A displays about half of the dopamine uptake velocity Vmax and cocaine analog binding Bmax values of wildtype DAT. V382A lowers dopamine's potency in inhibiting cocaine analog binding by six-fold. Cells expressing V382A or mixtures of V382A and wildtype DAT both display reduced plasma membrane and increased perinuclear expression, consistent with dominant effects of V328A on expression. V55A expresses normally but reveals a 1.7-fold-lower Km for dopamine uptake. Individuals with these human DAT protein variants could display altered dopamine systems.
Article: Dopamine efflux via wild-type and mutant dopamine transporters: Alanine substitution for proline-572 enhances efflux and reduces dependence on extracellular dopamine, sodium and chloride concentrations[Show abstract] [Hide abstract]
ABSTRACT: The dopamine transporter (DAT) can mediate not only inward uptake of dopamine, but also its outward efflux by mechanisms that have been only partially elucidated. DAT-dependent dopamine efflux can be studied kinetically and apparent substrate affinity and V(max) values determined. We now report that wild-type DAT displays apparent affinities for efflux more than 300-fold lower than those for uptake. Efflux rates are enhanced by increased extracellular concentrations of dopamine or amphetamine and by lowered extracellular concentrations of Na(+) or Cl(-). Alanine substitutions for six proline residues located in or near DAT transmembrane domains increase apparent affinity and decrease V(max) values for dopamine efflux mediated by these mutant transporters. Mutant 12P572A displays increased DAT efflux with reduced dependence on ion or dopamine concentrations. These data add to evidence for the specificity of transporter-mediated efflux processes and begin to elucidate DAT candidate domains that may be preferentially involved with efflux activities.
Article: Dopamine Transporter Mutants with Cocaine Resistance and Normal Dopamine Uptake Provide Targets for Cocaine Antagonism[Show abstract] [Hide abstract]
ABSTRACT: Cocaine's blockade of dopamine reuptake by brain dopamine transporters (DAT) is a central feature of current understanding of cocaine reward and addiction. Empirical screening of small-molecule chemical libraries has thus far failed to provide successful cocaine blockers that allow dopamine reuptake in the presence of cocaine and provide cocaine "antagonism". We have approached this problem by assessing expression, dopamine uptake, and cocaine analog affinities of 56 DAT mutants in residues located in or near transmembrane domains likely to play significant roles in cocaine recognition and dopamine uptake. A phenylalanine-to-alanine mutant in putative DAT transmembrane domain 3, F154A, retains normal dopamine uptake, lowers cocaine affinity 10-fold, and reduces cocaine stereospecificity. Such mutants provide windows into DAT structures that could serve as targets for selective cocaine blockers and document how combined strategies of mutagenesis and small molecule screening may improve our abilities to identify and design compounds with such selective properties.
- [Show abstract] [Hide abstract]
ABSTRACT: This review presents the remarkable advances that have been achieved in marijuana (cannabinoid) research, with the discovery of specific receptors and the existence of naturally occurring cannabis-like substances in the human body and brain. The last decade has seen more rapid progress in marijuana research than any time in the thousands of years that marijuana has been used by humans, particularly in cannabinoid genomics. The cDNA and genomic sequences encoding G protein-coupled cannabinoid receptors (Cnrs) from several species have now been cloned. Endogenous cannabinoids (endocannabinoids), synthetic and hydrolyzing enzymes and transporters that define neurochemically-specific cannabinoid brain pathways have been identified. Endocannabinoid lipid signaling molecules alter activity at G protein-coupled receptors (GPCR) and possibly at anandamide-gated ion channels, such as vanilloid receptors. Availability of increasingly-specific CB1 and CB2 Cnr antagonists and of CB1 and CB2 Cnr knockout mice have increased our understanding of these cannabinoid systems and provides tantalizing evidence for even more G protein-coupled Cnrs. Initial studies of the Cnr gene structure, regulation and polymorphisms whet our appetite for more information about these interesting genes, their variants and roles in vulnerabilities to addictions and other neuropsychiatric disorders. Behavioral studies of cannabinoids document the complex interactions between rewarding and aversive effects of these drugs. Pursuing cannabinoid-related molecular, pharmacological and behavioral leads will add greatly to our understanding of endogenous brain neuromodulator systems, abused substances and potential therapeutics. This review of CB1 and CB2 Cnr genes in human and animal brain and their neurobiological effects provide a basis for many of these studies. Therefore, understanding the physiological cannabinoid control system in the human body and brain will contribute to elucidating this natural regulatory mechanism in health and disease.
Article: Dopamine Transporter Transmembrane Domain Polar Mutants: ΔG and ΔΔG Values Implicate Regions Important for Transporter Functions
Article: PI3, PKC and MEK1/2 kinase regulation of dopamine transporters (DAT) require N-terminal DAT phosphoacceptor sites
Top Journals
Brookhaven National LaboratoryNew York City, New York, United States
National Institutes of Health
베서스다, Maryland, United States
- Molecular Neurobiology Research Branch


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How can we explain continued public support for Barack Obama's extremist spending plans, even though it is painfully obvious that his much-touted "remaking America" means mortgaging the financial future of young people with trillions of dollars in debt? Are the American people really willing to let the government be our nanny, manage our economy, federalize our schools, and decide which businesses can keep their doors open, what health care will be permitted, who will get new jobs and how extravagant will be the foreign handouts as Obama "rejoins the world community"?
One answer to these questions may be what has been taught over the last 30 years in U.S. colleges and universities, where the radicals of the 1960s have become tenured professors. David Horowitz has made it his life mission for the last two decades to expose the hypocrisy of professors pushing propaganda instead of education.
The latest of his several books on the academic left is called "One-Party Classroom: How Radical Professors at America's Top Colleges Indoctrinate Students and Undermine Our Democracy" (co-authored with Jacob Laksin; Crown Forum). "One-party" does not refer just to the fractious Harry Reid Democratic Party -- full-blown Marxist socialism is the "one party" that is indoctrinating students in the classroom.
Horowitz documented 150 college courses at 12 elite universities, from Columbia in New York to the University of California at Santa Cruz, which he calls "the worst school in America" and whose highest-ranking professors are the communist lesbians Angela Davis and Bettina Aptheker. Other institutions along the way include Duke, Penn State, the University of Colorado and the University of Southern California.
Horowitz quotes directly from the syllabus of each course he critiques, lists assigned readings, and reports on the credentials and background of the instructor paid to teach the course. The most offensive departments are women's studies, black studies and peace studies.
These so-called academic departments teach students to hate America, to believe that women, blacks and all minorities are the victims of oppression and racism, and that America is a land of injustice that needs drastic change in our social structure. The universities teach William Ayers-style "social justice," which is the template for a socialist political agenda.
Phyllis Schlafly is a national leader of the pro-family movement, a nationally syndicated columnist and author of Feminist Fantasies.
TOWNHALL DAILY: Be the first to read Phyllis Schlafly's column. Sign up today and receive Townhall.com daily lineup delivered each morning to your inbox.


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IP Video Communications Corporation
|IP Video Communications Corporation Patent applications
|Patent application number
|UNIVERSAL PACKET LOSS RECOVERY FOR DELIVERY OF REAL-TIME STREAMING MULTIMEDIA CONTENT OVER PACKET-SWITCHED NETWORKS - The Universal Packet Loss Recovery System (UPLRS) is capable of recovering end-to-end network packet losses to obtain reliable end-to-end network delivery of multimedia streaming content over IP networks where packet losses appear above the transport layer. The UPLRS incorporates the use of Packet Forward Error Correction Coding (FEC) with packet interleaving processing prior to transport. Packet FEC is an error correction coding method at the packet level to improve link transmission reliability. At the source end of the packet-switching network, the Packet FEC scheme encodes a stream of transport multimedia content packets by including redundant packets in the stream to allow for the recovery of lost packets by the Packet FEC decoder at the user end of the packet-switching network. Since lost packets appear only above the transport layer in the IP network protocol stack, Packet FEC can be viewed as a transport layer or an application layer coding method.


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Focused Review ARTICLE
Computational Grounded Cognition: a new alliance between grounded cognition and computational modeling
- 1Institute of Computational Linguistic "A. Zampolli," National Research Council, Pisa, Italy
- 2Institute of Cognitive Sciences and Technologies, National Research Council, Rome, Italy
- 3Department of Psychology, Emory University, Atlanta, GA, USA
- 4Centre for Robotics and Neural Systems, University of Plymouth, Plymouth, UK
- 5Division of Cognitive Sciences, University of Potsdam, Potsdam, Germany
- 6Department of Psychology, Social Science Centre, University of Western Ontario, London, ON, Canada
- 7Cognitive and Information Sciences, University of California, Merced, CA, USA
Grounded theories assume that there is no central module for cognition. According to this view, all cognitive phenomena, including those considered the province of amodal cognition such as reasoning, numeric, and language processing, are ultimately grounded in (and emerge from) a variety of bodily, affective, perceptual, and motor processes. The development and expression of cognition is constrained by the embodiment of cognitive agents and various contextual factors (physical and social) in which they are immersed. The grounded framework has received numerous empirical confirmations. Still, there are very few explicit computational models that implement grounding in sensory, motor and affective processes as intrinsic to cognition, and demonstrate that grounded theories can mechanistically implement higher cognitive abilities. We propose a new alliance between grounded cognition and computational modeling toward a novel multidisciplinary enterprise: Computational Grounded Cognition. We clarify the defining features of this novel approach and emphasize the importance of using the methodology of Cognitive Robotics, which permits simultaneous consideration of multiple aspects of grounding, embodiment, and situatedness, showing how they constrain the development and expression of cognition.
Keywords: grounding, embodiment, situatedness, cognitive robotics, situated simulation
Citation: Pezzulo G, Barsalou LW, Cangelosi A, Fischer MH, McRae K and Spivey MJ (2013) Computational Grounded Cognition: a new alliance between grounded cognition and computational modeling. Front. Psychology 3:612. doi: 10.3389/fpsyg.2012.00612
Received: 27 July 2012; Accepted: 21 December 2012;
Published online: 22 January 2013.
Edited by:Anna M. Borghi, University of Bologna, Italy
Reviewed by:Frank Guerin, University of Aberdeen, UK
Ivilin P. Stoianov, University of Padua, Italy
Copyright © 2013 Pezzulo, Barsalou, Cangelosi, Fischer, McRae and Spivey. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.
*Correspondence: email@example.com


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Christopher David James Dent (born 20 January 1991) is an English cricketer. He is a left-handed batsman who plays for Gloucestershire. He was born in Bristol.


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1047. Levi32
Quoting beell:
I'd say stronger on the GOES analysis, based on the fact that the GFS has not a single east, northeast, or northerly wind barb on that image. The upper low seems more closed on satellite, though there is some uncertainty since it would be more defined the lower you go, until about 500mb.
Member Since: November 24, 2005 Posts: 635 Comments: 26780


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Who would name their kid Clay?
H m m m . . . I wonder who would name their child "Yikes" ? ? ?
H m m m . . . And I always thought a "kid" was a young goat.
This is a recurring issue for us, as DH is Jewish and generally grumpy from after Thanksgiving to the New Year; I am not exactly the Martha Stewart of Christmas, but it is my family's big holiday, so it means a lot to me that he suck it up for a few things. Honestly, if I can sit through hours of Seder dinner every year, he can put on a smile when people are giving him presents.
That said, I also believe that the person to whom it matters more needs to take responsibility for arranging things to her liking, and not simply expect the other partner to fall in line and follow orders -- or worse, be expected to somehow intuit what is supposed to be done and drop everything else to make that happen. I have tried really hard to see where DH is coming from (if you don't celebrate Christmas, it's a completely overwhelming time of year), and over the years we have managed to minimize his "required" involvement to the fewest things possible (e.g., he helps muscle the tree into the house and put it up, but I enlist the kids to decorate it with me).
Thanks for a new phrase to help my wife understand the side of her that comes out at Christmas. We already use the "crazy Christmas lady" tag, of course - how could we not? - but "an elf on Red Bull" should also prove helpful.
The Juggle examines the choices and tradeoffs people make as they juggle work and family. The site provides readers with news, insight and tips on parenting, workplace issues, commuting, caregiving and other issues busy readers with families face. It is also a place for readers to share and compare their own work-and-family experiences and to seek advice and recommendations. The Juggle is includes regular contributions from other staffers at the Journal. Contact the Juggle with ideas or suggestions at email@example.com


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Street Fighter Chronicles
Its a small project that I am doing for fun, trying to imagine what would the characters of SF II look like later in the years to come. More of a re-design challenge if you will.Stories that come with the art are secondary and not canon, so they shouldn't be taken too seriously. After all I am not a writer and moreover, English is not my native language So enjoy the images and feel free to leave your comments!
Capcom and the devs of Street Fighter V could take notes from you.
Aren't there any more of these? What about the rest of the characters?
English is not your native language? Damn but you're good! I'm a writer and I was hooked to the story (and the pictures, of course, but that's to be expected), I've got nothing but respect for you.
That's really great, had this happened in Street Fighter, it would be a much better series plot-wise. Too bad Capcom doesn't give a damn.
Amazing job.
These are brilliant, excellently done. I'd love to see you expand outwards to the Alpha characters as well.
just awesome!
C'mon there has to be some good conclusions...Ryu back to normal and stuff!
Feels kinda 'anti-Street Fighter.'
I had no idea Street Fighters had such terrible luck.


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Results 1 to 1 of 1
-06-14-2005 #1
Ligashesky brings energy in trying to revamp kick, return teams
By Bill Coats
Of the Post-Dispatch
What's a rarer sighting: a) an ivory-billed woodpecker, until recently thought to be extinct, or b) the same man occupying the second-floor office of the special-teams coach at Rams Park for more than one year?
Mike Stock, Bobby April and Larry Pasquale might well choose b). All were hired and fired as Mike Martz's special-teams coach over the past five seasons. Of the three, only April lasted more than one year in St. Louis.
Faulty special-teams play has been a constant on Martz's watch, and the stumbling and bumbling never were more evident than last season. The Rams, under Stock, ranked 31st in the 32-team NFL in punt returns (4.8-yard average) and kickoff returns (19.1). They didn't cover any better, finishing 30th in defending punt returns (11.9) and 32nd on kickoffs (25.5).
And they saved their worst for last: Atlanta's Allen Rossum set a league postseason record by piling up 152 yards in punt returns, including a 68-yard touchdown dash, in the Falcons' 47-17 drubbing of the Rams in the NFC semifinals on Jan. 15. Stock was dismissed five days later.
Nonetheless, Bob Ligashesky said job security wasn't atop his priority list when the following day he decided to accept Martz's offer to replace Stock. "I didn't really think about that," said Ligashesky, 43. "You really think about more that it's an opportunity to become part of a successful organization."
Martz and Ligashesky worked together from 1986 to 1988, as assistant coaches at Arizona State. Martz moved up to the NFL in 1992, as an assistant with the Los Angeles Rams. Ligashesky, a Pittsburgh native, stayed with college football, moving on to Kent State, Bowling Green and finally Pittsburgh from 2000-03.
His first, and only, pro experience came last year as an assistant to special-teams coach Pete Rodriguez in Jacksonville. In 2004, the Jaguars ranked in the top 10 in the NFL in most special-teams categories.
Martz said he hadn't kept in touch with Ligashesky and was surprised when his former colleague's name kept coming up as he asked others around the league about candidates to succeed Stock. "They said, 'There's this guy down in Jacksonville ... '" Martz said.
Ligashesky was given considerable opportunity during the recent three-day minicamp to drill his various units. According to Martz, he did so at a breakneck pace and yet with painstaking precision.
"He's high-energy," Martz said. "I think the approach and the way he goes about it, the attention to details, is very significant. It's a marked difference." Ligashesky said his frenetic behavior on the field comes naturally. "I don't really think about it when I'm out there," he said. "I just know that I'm trying to get to everybody in a small amount of time."
Building solid special teams, Ligashesky explained, is rooted in finding committed individuals and then refining their skills. Noting that 20 percent of the plays in a typical NFL game involve special teams, he said: "It all starts with attitude and belief in its importance. The players have to buy into what you're doing, and then it's executing the technique and then being able to adjust as situations occur."
Then comes the teaching part, Ligashesky explained. "Basically I believe in ongoing skill and technique development, which means trying to get the players to execute at the highest level, to the best of their ability," he said. "And no matter what the scheme we decide to run, it has more to do with how you execute the technique than the actual scheme itself."
As for his personnel, Ligashesky said: "It doesn't matter if they're starters or if they're backups. Let's get the best players for that phase out of the 53 and let's go." In their offseason transactions, including the draft and the recruitment of rookie free agents, the Rams searched for players who could provide help on special teams. Critics had charged that such an emphasis wasn't always in place in the past.
Ligashesky said that first, he wants special-teams players "who believe strongly in its importance." Among the Rams, "I would say the majority of them do, because they all want to be successful," he said. "That is one of the most exciting things that's happened to me since I've been here. Everybody has been so open and receptive to us being successful on special teams. ...
"They want to contribute to the success of this football team. And I think special teams is probably one of the easiest ways for us to be more successful."
Martz's special guys
Mike Martz has had glowing words for Bob Ligashesky, the most recent special-teams coach he has hired during his five-year tenure. (Story, D3)
But that's nothing new. Here's what Martz said about the other special-teams coaches at the time they were hired:
Larry Pasquale
"The guy we've got now, he's the best in the league." - Feb. 24, 2000
Fired Jan. 2, 2001
Bobby April
"In my estimation, he's the best in the game at what he does. Bobby loves what he does. He has a great passion for what he does, and he's a great communicator and teacher with the players." - Aug. 15, 2001
Contract not renewed after 2003 season
Mike Stock
"It was a no-brainer for us. He came so highly recommended, that I felt like we had to get him in. He's exactly what I'm looking for." - Feb. 23, 2004
Fired Jan. 20, 2005
Bob Ligashesky
"I've always been extremely impressed with his work ethic and his commitment. He's a bulldog. He's just a mad dog. ... He's a high-energy guy, which is what we want." - Jan. 21, 2005


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Originally posted by dadfortruth1where is all the water going?
Originally posted by canofnothing
reply to post by dadfortruth1
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- 85Promote
Throw Pillow
Old Double Barrel Stevensby Captive Images Photography
Throw Pillow made from 100% spun polyester poplin fabric, a stylish statement that will liven up any room. Individually cut and sewn by hand, each pillow features a double-sided print and is finished with a concealed zipper for ease of care. Sold with or without faux down pillow insert.
An old double barrel Stevens 12 guage shotgun shown open and with shells.
keywords; stevens, double, double barrel, shotgun...
I promote anything with a firearm in it! :-))
super cool!!! :)) that pillow is so for a man's country house :D ♥
I'm with you Lyle! Thank You very much :)
Thank You Carina! I agree with you...
Nice detail photo John
Thanks Dick... I appreciate it!
Thanks Monika!
Beautiful piece!
Oh Yeah! ✯ ✯ ✯ ✯ ✯ 👍
Thanks for the comments everyone!
awesome gun! and well captured
Fabulous work!
Beautiful workmanship and great capture!
Thank You Bret, Peaky40, and John! I appreciate the comments... This one gets framed and is really popular at my shows...
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Underwear/clothes after c-section.
Batty aka Gothy Spice #Team Wizard, momma to Bat 3/22 and Vampire 1/02
Married to Perv 3/08
Big ol' granny panties. And loose-fitting pajama pants.
Eat whatever you feel like the night before (as late as you can, like if your cut off is midnight, then eat at 11:30). And I can't think of any reason why you wouldn't be able to DTD the night before. Sounds like a good idea to me! Take it easy with the stool softener, though. Maybe one dose, if you really want to, but nothing extra.
I wore maternity jeans home (the high band kind), and was fine. This time I might do leggings and a tunic. Not sure. You'll still probably have a bandage when you go home, so it will be protecting your incision from your clothes a little.
wife to a great guy, mommy to THREE cutie pies!
Don't try to get panties for under the incision, its very low. Def. go for loose fitting cotton granny panties. They will give you stool softeners in the hospital but I think it would be fine to take 1 daily from now until your c-section since they don't cause diarrhea or anything. The softer the better after any surgery. Unless you are on pelvic rest for something you can DTD as much as you want. Loose high cut sweats or pajamas are good too, avoid low cut pants that might irritate the incision. Good luck!
Mom to 2 boys. 2 and 5yo when brother #3 arrives! High risk, Lovenox shooter for the final time. The countdown begins!
Batty aka Gothy Spice #Team Wizard, momma to Bat 3/22 and Vampire 1/02
Married to Perv 3/08
Granny panties. I don't think there are panties that could go under the incision. It is so low, almost on your vagina. Definitely DTD the night before if you want. I would not take stool softeners before because you are going to be on a lot of meds and you don't want to take anything that won't go with the other meds.
I just stayed in the hospital gown for most of the time, because there is a lot of bleeding. I doubt you will want to speed up your discharge after the c-section unless you are some kind of superwoman. It is going to take a huge effort to even walk again- at least it did for me. Picking up the baby is difficult. Just let them take care of you and don't pressure yourself to get out of there too fast.
I wore a maternity skirt home and plan to again this time. Good luck! You will do great!
Yes, I kept my baby with me the whole time. My husband was there to pick her up, though. If you stay alone, you will probably have to call the nurses to help you when baby cries. But they were super helpful in my hospital. I'm sure they will be for you too, especially once they find out about your work history. Your baby doesn't really need any food for a little while, so the first couple days is more about comfort and practice rather than nutrition.
Also, you wont be able to cosleep after the surgery because it is too dangerous for the baby since you will be on so many meds and might be fading in and out, so you will have to put baby back in the basinett every time.


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Rih in the Woo
New fashion, a new reality show and MAC cosmetics are in the works for Rihanna this fall. She'll be releasing more makeup with MAC, so of course the makeup giant will be sold out again for the holiday season. Besides music, Rihanna is setting herself up to be the biggest fashion icon of this generation other than Lady Gaga and it's well deserved.
(Photo: PacificCoastNews.com)
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Find Your Cruise...
Find Your Cruise...
Read 188,897 opinions of real cruises all written by real people! All of them are completely unedited!View all Reviews
By Seymour, Wokingham on 11th Nov 2012
Royal Caribbean
By Mmou, Limassol on 17th Apr 2013
Cruising the Atlantic is a great way to enjoy everything that a cruise ship has to offer. Crossing the Atlantic for 6 nights gives you plenty of time to enjoy the fine dining, entertainment and activities that the cruise has to offer, or simply relax on deck!
Need some ideas for shore excursions whilst in New York? Click here
For all of those non-flyers out there, it's a great opportunity to get yourself across to America without having to go near a plane.
Why not choose the original transatlantic cruise from Southampton to New York aboard the luxurious Cunard Queen Mary 2?
Other cruise lines offer slight varieties around the transatlantic crossing. Azamara Club Cruises sail across the Atlantic to San Juan. Princess Cruises offer longer cruises which visit ports around Europe before crossing the Atlantic to Florida.
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I too, recently came across the term "bigendered" on wikipedia. I'm
biologically male but have always felt like i had two personas. On one
side, the side everyone in RL knows, is a rather sensitive and patient
male. And on the other side, there's an impatient tomboy. It's been
really frusterating and confusing up until now. I thought i might have
a multiple personality type disorder or something. I'm so glad I found
others who are in the same boat...
Being aware of your two sides is accepted as proof that you are not suffering from multiple personality.
Im bigendered and I have MPD o.o Its a weird thing to experience but I just wanted to speak haha sorry I'm new here and do not really know what to do.
Well, I recently came across the term oon wikipedia as well. I definitely relate!!! <br />
So don't worry, like sarahdavids said, its a small boat, but it's afloat!!!
try to breathe and realize people should be friends for the person you are you shouldn't feel like two differnt personas you should realize that is versitility and thats a desirable trait
The versatility point is a good one.
It's a small boat so far, but at least it's afloat.


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Aug 13, 2009
TEL AVIV [MENL] -- Israel's Elbit Systems has reported a profit decline in2009.
Aug 06, 2009
RAMALLAH [MENL] -- Thousands of children have been employed to construct andoperate the tunnel network between the Gaza Strip and Egypt.
Mar 20, 2009
TEL AVIV [MENL] -- An Israeli defense firm has won an award to supplyarmored jeeps to the nation's police force.
Feb 10, 2009
JERUSALEM [MENL] -- Israel has approved a $600 million plan for the resupplyof the military in wake of the war with Hamas.


text:
What does HOVON stand for?
What does HOVON mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: HOVON.
We've found a total of 1 definition for HOVON:
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Hemato-Oncology Foundation for Adults in the Netherlands
Still can't find the acronym definition you were looking for? Use our Power Search technology to look for more unique definitions from across the web!
"HOVON." Abbreviations.com. STANDS4 LLC, 2016. Web. 12 Feb. 2016. <http://www.abbreviations.com/HOVON>.


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FitDay Member
Join Date: Apr 2013
Posts: 4
New here: Long Introduction.
Hi all! I found this site earlier this week. I really need some accountability!
My story:
I'm a 45 year old woman from Ohio. I have yo-yo'ed with my weight for about 20 years. On the high end since having my first child in '02.
I started working out again in '09 (I think) and have maintained a 4-6 day a week workout schedule. I have great muscles--they are just covered by loads of fat. My body has settled on a weight that is pretty doggone close to what it was when I started working out. I know "muscle weighs more than fat" but my body is so very happy with retaining that extra fat.
I tinkered with paleo/primal eating but I'm outnumbered in my house with people who really aren't on board with that. I'm finding that an over all reduction in calories with an emphasis on plenty of protein is working for me so far. I just needed a place to keep track of it all...then I found this site.
My goal? I want to be a super hero. I want to expose my muscles to the outer world. I have a Wonder Woman hidden underneath my dowdy exterior!
Good news is since joining this site I have lost 2 lbs!
Thanks for having me.
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FitDay Member
Join Date: Feb 2013
Posts: 334
Welcome, Trent. FitDay is great for accountability - I can't tell you how many times I've not eaten something because I didn't want to have to enter it into my food log. It doesn't always work though - today I ate and entered 2 potato chips into my log - but I stopped at 2 instead of eating the whole bag.
If you want some more accountability - and encouragement - there's a weekly motivation thread you might want to look at and join in if you'd like. A new thread starts each Monday. People post their daily goals for the week and report back about how they're doing.
Age 61, Height 5'9"
March 2010 145 lbs, Jan 2013 173 lbs
1st Goal 145 lbs 5/25
New goal 140
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This isn't exactly Sergeant York, but, as Lt. Col. Patterson tells it, Kerry apparently rated his exploits (which earned him a Silver Star and a Purple Heart) too good simply to write home about: "Kerry and his crew returned within days, armed with a Super 8 camera he had purchased at the post exchange at Cam Ranh Bay, and reenacted the skirmish on film."
Before writing another word, I guess I better pay homage to Kerry's military service. But, frankly, I draw the line at paying homage to the reenactment of his military service. In fact, I find this behavior so extremely weird I quail at the thought of the man even possibly becoming president. Of course, such bizarre revelations -- a big picture window onto his nature -- could well be a drag on his White House run. Why? There is something so preening in his calculation, so self-conscious in his self-dramatization, that there is ample reason to question Kerry's perspective on reality -- or, rather, his own sense of place in it.
Then again, maybe Kerry's war record of fighting by day, filming by day-after shows a perfectly commendable, eyes-on-the-prize focus on the future, or at least his future. As the Boston Globe put it, we have to reckon with this "young man so unconscious of risk in the heat of battle, yet so focused on his future that he would reenact the moment for film. It is as if he had cast himself in the sequel to the experience of his hero, John F. Kennedy, on the PT-109." Crucial to remember, of course, is that the 1963 movie "PT-109" starred not JFK as JFK, but Cliff Robertson as JFK.
Author O'Neill, who took command of John Kerry's swift boat after Kerry left Vietnam, and who actively opposes his presidential candidacy, includes this reminiscence in his book, which may explain Kerry the auteur: "A joke circulated among Swiftees was that Kerry left Vietnam early not because he received three Purple Hearts, but because he had recorded enough film of himself to take home for his planned political campaigns." Funny enough to the guys, then. But here we are, 35 years later, and John Kerry, the movie, is part of a presidential campaign, and with Steven Spielberg's cinematic blessing. Will this long-in-the-making epic be a 21st-century success?
Here's how: George W. Bush wins a second term, and John Kerry wins an Oscar.
Diana West is the author of American Betrayal: The Secret Assault on Our Nation's Character (St. Martin's Press, 2013), and The Death of the Grown-Up: How America's Arrested Development Is Bringing Down Western Civilization (St. Martin's Press, 2007).
Rush Limbaugh defends Rubio's debate answer: He's absolutely right that Obama knows what he's doing | Allahpundit
Time for Team Hillary to break out the gender card for young liberal women who prefer Sanders | Allahpundit


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Leliel a swamps treasure by mangakasanWatch
©2013-2016 mangakasan
Leliel is a OOAK sculpt which measures about 4 inch from base to horn, he was 100% handmade (no molds were used) with polymer clay over a wired armature frame, his eyes are cast from clear resin and are hand painted, he was painted with acrylics,mica powders and pastels with many layers of varnish, his hooves and horn glow blue in the dark.
This is a piece which i started early Januari this year, he was supposed to be a remake of an older sculpt i did of (foal) Engel, but because of lack of time he sat half sculpted on my desk for almost a whole year, but last month i picked him up again and was wondering what i would do to him as much time passed and i thought he looked kind of boring and i didn't like certain bits anymore, but i diddnt want to trow him away either so i just thought...heck! i am just gonna continue and see what happens....well this is what happened then....
Commissions are closed until somewhere next year.
Art by Jen W
What kind of varnish did you use?
OMG, this is so awseome *~*
How to make the water drop ?
How to make the water drop ?
What a beautiful piece, I love what you did.
Mind if I ask how you got that paint effect done? Like, it looks almost as if the paint is smoothly blurred into the next colour, or like it was powdered on.... how did you create that effect?
Also, I can't even begin to imagine being able to make something as beautiful and perfect as this. I love it with each bit of my heart <3 positively astounding work~!!!
you can get the smooth effect in different ways like some use airbrush to get it to look that way, but i just start by put a primer coat on first, then i block in the base colors with acrylic paint and then layer after layer a pastel color/mica powder which i dust on, and finally i used the ticking technique (you take a very thin brush and paint small hairs individually), i did that to make a realistic transfer from the dark colors to the white. i hope this answered your question a bit XD
Beautiful work! I love the vivid colors and the droplets are very well done!
A beauty of a sculpture. The details are amazing Manga. And the colors are wonderfully vivid.
Wow so many fun little details on this one; I especially love the little splash on the base. Are the droplets made from resin?
No i used 3D lacquer for the droplets and splash (i could have used resin but it would take to long to dry XD
He's incredible, I'm amazed at the resin droplets of water and the crazy beautiful realistic details!
aww thank you! haha actually i didn't use resin for the drops but a lacquer XD
Gorgeous work!
amazing! the detail is just wow! :0
Reminds me of a Kelpie. n.n It's cute, whatever it may be.
wow... you did that WITHOUT A MOULD??? that's AMAZING!
You say you had him on your desk for a long time - how did you stop dust and dirt from stuck on him?
lol he was very dusty but i removed most with tape and the rest pretty much burnt away in the oven XD
Also, it looks amazing!
It looks like something from heaven! Amazing!
Wow, this is gorgeous! So detailed and beautiful colours!
Oh wow, those colours are totally unexpected but so beautiful! Love blue
yeah i had no real plan but i wanted to do something colorful/unnatural for a change XD haha and i happen to love blue too XD


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Register now for free, or sign in with any of these services:
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Know more about this business than we do? Cool! Please submit any corrections or missing details you may have.Help us make it right
Call Wink Eyelash Bar & Makeup Studio at (504) 509-5220 in Metairie, LA, for airbrush makeup application to achieve a long-lasting, natural look for your next big event.
We specialize in Airbrush Makeup Artistry and Eyelash Extensions. We cater to Brides-to-be, Models, and everyday Women in search of glamour.
Wink hosts a number of beauty events and parties for all occassions. Our signature event "The Makeup & Martini Mixer" is held once a month and features a beautiful makeover, professional photo shoot and complimentary cocktails.
It's not just Makeup. It's an Experience. Wink Eyelash Bar & Makeup Studio, is a luxury beauty boutique located at 911 Veterans Memorial Blvd in the heart of Metairie. We specialize in Airbrush Makeup Artistry and Eyelash Extensions. We cater to Brides-to-be, Models and Everyday WOMEN is search of glamour. We provide makeup services In-Studio or On-Location for all special occassions. ...
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There really isn't a bad thing I could say about Natashia. She answered all of my questions upfront and put my mind at ease, even when I didn't heed her advice on how I should look on my wedding day. Natashia knows best!!! She allowed me to see what the heavy smokey eyes would look like THEN showed me the soft romantic look that complemented my features and the dress perfectly.
I was also very...
Natashia made me feel and look like a super star i received so many compliments even after doing the 2nd line dancing. My makeup stayed fresh and light. She would receive more than 5 stars if it was possible. I loved everything from engagement photos to my wedding day. She also did my bridemaids and mom she was easy to work with and fun and fantastic price!!!!
Your PERSONAL makeup studio.


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10 Steps to Pick the Right Doctor
Whether you need a primary care doctor or a specialist, these 10 steps will ensure you find the right doctor for you. View Slideshow
Dr. Szafraniec's Experience
- Psychiatry
Board Certifications
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- Anxiety
- Bipolar Disorder
- Major Depressive Disorder
- Obsessive-Compulsive Disorder (OCD)
- Psychiatric Diseases
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Support & Service: You Need It, We Gladly Provide It.
Our #1 priority is you, the customer. If you need help with Agfa, Creo/Kodak, Fuji, Heidelberg or Screen platesetters, we have the service and parts that you need. We deliver fast service, so there is little downtime and all of our work is guaranteed!
Wonderful Customers & Counting
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Quality Equipment, Parts, & Lasers!
With over 10,000+ happy clients and counting, Platesetters has the most trusted equipment on the market.


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We are standing by to get your order started. Relax in knowing AutohausAZ.com can provide you with the best and lowest price Mazda Miata Power Steering Hose parts. Order Mazda Miata Power Steering Hose parts directly from our Mazda Miata Power Steering Hose auto parts online catalog. As soon as an item ships, we email your tracking number to you. When you order Mazda Miata Power Steering Hose parts from us, we will ship it from the closest warehouse we have it in stock. Be confident in knowing we offer a hassle free return policy. There is even more good news ahead. Shop securely for any Mazda Miata Power Steering Hose replacement parts you need.
Dan C. - Pacific Grove, CA: My shipment arrived yesterday, right on time, exactly what I had ordered and at a price at least 20% less than any other supplier! This is my first order with you and you have definitely earned my future business. Thanks alot.
John D. - Langcaster, MA: Happy! Thank you! I will order more VW or MB parts from you soon.


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Featured news
Energy Review looks to generate security
The sound of champagne corks popping in the offices of nuclear power bosses rang around the world yesterday when, as expected, the UK government committed to a new generation of fission reactors.
Everyone is digesting the DTI Energy Review, and despite weighing in at a coma-inducing 213 pages, the verdict would seem to be that it is short on detail. The review lists many proposals, most of which are for further consultation. On nuclear, a consultation on a policy framework is the modest goal.
At The Register.
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Posted by Glen Barber on 11/13/2013 9:34am tags: photo
More than 1,000 Indians are celebrating Brazil's indigenous cultures with a week long sports competition in the northern city of Porto Nacional. Brazil's federal Indian agency that cosponsors the games says they are one of the biggest indigenous sporting events in the Americas. Thirty-eight ethnic groups from across the vast country are competing in 10 events that include archery, football, swimming, spear throwing and canoeing. Many of the competitors are using their traditional dress and markings. More National and World News
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What is RM Cash
Complete the look of your outfit with a stylish new belt from some of the top brands in motocross apparel. At Rocky Mountain ATV/MC we carry womens casual belts in cool, carefree yet sturdy styles designed to withstand the years and the rigors of your active lifestyle – all while adding a touch of flair to your outfit. Traditional buckle or metal clasp buckles, reversible sides or one way designs – check out our selection of womens casual belts to get yours coming in the mail today!
Rhys in NC
Been using this daily and it does what belts do so I can't complain.Read All Reviews
Derek in NY
Terrible Belt. I try to stay away from Fox, and this belt reminded me why. Very low quality and durability. Will not last, too long.Read All Reviews


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Skin Balancing Face Oil, 50ml
- Instructions for use:
- - Dispense two or three drops onto fingertips
- - Gently press into face, neck and décolletage until absorbed
- - Use morning or night
- - 50ml/ 1.6fl.oz.
- Ingredients: Carthamus Tinctorius (Safflower) Seed Oil, Caprylic/Capric Triglyceride, Persea Gratissima (Avocado) Oil, Macadamia Ternifolia Seed Oil, Rosa Canina Fruit Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Butyrospermum Parkii (Shea Butter) Oil, Oenothera Biennis (Evening Primrose) Oil, Glycine Soja (Soybean) Oil, Chamomilla Recutita (Matricaria) Flower Extract, Calendula Officinalis Flower Extract, Althaea Officinalis Root Extract, Rosa Gallica Flower Extract, Bellis Perennis (Daisy) Flower Extract, Echinacea Purpurea Extract, Viola Odorata Extract, Viola Tricolor Extract, Symphytum Officinale Leaf Extract, Daucus Carota Sativa (Carrot) Root Extract, Tocopherol, Retinyl Palmitate, Beta-Carotene, Fragrance (Parfum)*, Benzyl Alcohol*, Cinnamyl Alcohol*, Citral*, Eugenol*, Coumarin*, Benzyl Salicylate*, Geraniol*, Linalool*, Benzyl Benzoate*, Citronellol*, Hexylcinnamal*, Limonene*
- *From Natural Essential Oil
Jurlique's luxuriously lightweight face oil has been developed to restore balance to all skin types, absorbing quickly for a velvety finish. This high performance blend targets visible signs of dryness and uneven skin texture with moisturizing Shea Butter, Avocado and Jojoba Oil. Firming Rose Hip and Safflower Oil reduce the appearance of fine lines and wrinkles, whilst antioxidant Vitamin E helps protect against environmental aggressors.
- Made in Australia - Helps guard against moisture loss - Blended with hydrating and softening Evening Primrose, Macadamia Seed Oil and Marshmallow
As seen in THE EDIT magazine
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A logo design is needed. I want the logo to be three oak tree trunks that come together to form one big oak tree. The oak trees should be full of life and in full blossom. The name of the comapny is Trinity Apparel, and the name should appear in the logo.
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Celebrating the launch of the Phantom Fuse boardshort in conjunction with the U.S. Open of Surfing 2012, Hurley have commissioned Dalek to create this installation entitled "STABILIMENTUM". Featured at the Hurley H Space Gallery in Costa Mesa, California. the exhibition showcases the renowned artist's colorful geometric take of the brands signature boardshort design. Allowing visitors to be completely immersed in the displayed universe, the exhibit also features appearances from Phantom Fuse-inspired products including the likes of the Dalek-assisted Hurley x Nike Free Run+ 3 NRG and a series of hand-painted fixed gear bikes from LDG alongside a custom surfboard. "STABILIMENTUM" will remain on display through September 15, 2012.
Hurley H Space Gallery / 1945 Placentia Ave. / Costa Mesa / CA 92627 / United States


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Announcing Cotton Spandex Jersey!
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