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War Books
List of famous war books, listed alphabetically with jacket cover images of the books when available. Information for these popular war books is included as well, such as the author's name and the book's publication date. This list includes the best war novels, textbooks, and stories, so use it to find books you haven't already read and add them to your reading list.
List contains books like Slaughterhouse-Five and Catch-22.
This list should answer the questions, "What are the best war books?" and "What are the most famous war books?"
Note that some books on this list might be currently out of print, but you can purchase most of these notable war titles on Amazon with just one click.
- 1
A Bridge Too Far Cornelius Ryan
- 2
A Farewell to Arms Ernest Hemingway
- 3
Immediate Action Andy McNab
- 4
A Long Long Way Sebastian Barry
- 5
La radiologie et la guerre Marie Curie
- 6
A Nghu Night Falls David Sherman
- 7
Now the Hell Will Start Brendan I. Koerner
- 8
A Rock and a Hard Place David Sherman
- 9
Armageddon in Retrospect Kurt Vonnegut
- 10
On War against the Turk Martin Luther
- 11
At the Point of a Gun David Rieff
- 12
Seven Troop Andy McNab
- 13
The Last Night of Love, The First Night of War Camil Petrescu
- 14
Black Hawk Down Mark Bowden
- 15
Blood rites Barbara Ehrenreich
- 16
The Lucky One Nicholas Sparks
- 17
Bomber Len Deighton
- 18
Britain At Bay Spenser Wilkinson
- 19
Captain Sword and Captain Pen. James Henry Leigh Hunt
- 20
Causes of war Stephen Van Evera
- 21
Charlie Don't Live Here Anymore David Sherman
- 22
China Attacks Steven W. Mosher
- 23
Clausewitz and the state Peter Paret
- 24
DRAGONS KINGS DRAGONLING 6 Jackie French Koller
- 25
European Armies and the Conduct of War Hew Strachan
- 26
Faith, Reason, and the War Against Jihadism George Weigel
- 27
Fredericksburg Kirk Mitchell
- 28; buy at
- 29
Gate of his enemies Gilbert Morris
- 30
Gates of Fire Steven Pressfield
- 31
Gregor and the Code of Claw Suzanne Collins
- 32
Hemingway on war Ernest Hemingway
- 33
How the children stopped the wars Jan Wahl
- 34
In the Company of Heroes Mark Bowden
- 35
King Rat James Clavell
- 36
Lords of the ocean James Nelson
- 37
Main Force Assault David Sherman
- 38
Ordered to Die: A History of the Ottoman Army in the First World War Edward J. Erickson
- 39
Out of the Fire David Sherman
- 40
Political Victory Brian Crozier
- 41
Preface to peace Norman Angell
- 42
Private Angelo Eric Linklater
- 43
Random Harvest James Hilton
- 44
Reporting the War John Byrne Cooke
- 45
Shattered Jennifer Armstrong
- 46
Stealth Jihad Robert Spencer
- 47
Talking peace Jimmy Carter
- 48
The Art of War Sun Tzu
- 49
The Big Time Fritz Leiber
- 50
The bronze horseman Paullina Simons
items 1 - 50 of 78


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Otherworldly by dio-03Watch
©2014-2016 dio-03
Sometimes I dream of worlds and wonder if they dream back.
Man, this is awesome...I just think it needs one thing to put it over the top! A little atmospheric perspective towards the background would really help give it more depth. Other than that I wouldn't change a think. Love the way you rendered the rocks, and those clouds are gorgeous.
I totally see what you mean on the atmospheric perspective. Thanks for the insightful comment. I might give it a second pass sometime.
Cool man, no worries! I've been watching a lot of concept art tutorials lately and atmospheric perspective is a basically the main tool they use to show depth, other than standard perspective. If you just de-saturate some of the parts of the cliffs that are further away that would really help. Like I said, other than that its an amazing piece!
Thanks for sharing your dream. Really nice man.
Love it man!
Beautiful! Getting better and better, Daniel!
Really love this one Dan! That red is popping like it's its job! Great lookin stuff.

subset: commoncrawl


text:
Batko specializes in the manufacturer of protective enclosures for surveillance equipment and offers a wide range of tough, easy-to-install products. Since the early 1980's Batko has been developing and delivering enclosures to put cameras in locations previously thought to be impossible, this was demonstrated with the introduction of their popular insulated enclosures in 1987.
Now offering over 200 enclosures for cameras, DVR's and monitors along with various protection accessories, BATKO is a well-established leader in North America. With a focus on simplicity and providing the best value, BATKO designs both indoor and outdoor enclosures, as well as specialist enclosures for extreme environments.
For warranty information click here: https://www.batko.com/footer/garanties.php
Tel: (418) 286-6842 / 800-463-1455
Fax: (418) 286-4201 / 800-261-3514
PanaVise is a major manufacturer of mobile electronics mounts for GPS units, satellite radio receivers, mobile video screens, CCTV camera mounts, mobile data terminals and circuit board holders. Their products are designed to last in the punishing environment of mobile electronics where large temperature fluctuations, vibrations and high levels of impact happen every day. In the security industry, PanaVise is a premier supplier of high quality CCTV camera mounts with a range that will suit every application and last in just about any environment.
Having been in the industry for over 50 years PanaVise know that it's not just great products that matter its great service as well. When you contact them via phone or email you will always get a prompt efficient response to your enquiry and helpful suggestions as to the types of products that might suit your needs.
For warranty information click here: http://www.panavise.com/index.html?PageID=56&PageName=Warranty&sec_id=56&sec_status=[sec_status]class=
PanaVise Products, Inc.
Tel:(800) 759-7535
Fax: (800) 395-8002
- 15 vent holes (0.375'' spaced over 6'' L)
- Aluminum construction
- Use with FB-2012
- FR-DVR6U can be installed front facing
- The FSMDVR6U can be used as well with the Le FR-CPU01, FR-TLR01, FR-1816, FR-1819, FRE-1816, FRE-1819
- Can be installed sideways to provide access to the rear
- Strong but lightweight
- Aluminum construction, 11 Ga
- Construit en aluminium 8 ga
- Robust & lighweight
- Easy to install
- 8 ga. aluminium construction
- Robust & lighweight
- Easy to install
- Easy to install
- Very strong
- 8 ga. aluminum construction
- 5 ga. aluminium construction
- Robust & lighweight
- Modular system: Base, Shaft and Head screw together
- Two aluminum shafts [0.5" (12.7mm) diameter] will make a 2" (50.8mm), 4" (101.6mm) or 6" (152.4mm) long mount. 1/4-20 stud with lockring
- Fully adjustable at the camera (190° Tilt, 360° Turn & 360° Rotation)
- Knob and tamper-resistant set-screw adjusting options included. Matching vinyl cover adds a finished look!
- Includes 2" (50.8 mm) round Base with four 0.188" (4.8mm) holes on 1.6" (40.6mm) bolt circle for solid surface mounting, and a T-Bar Clip for drop ceiling rails
- 0.5" (12.7mm) diameter solid steel shaft
- Length of mount from base to front of mount: 4.0" (102mm)
- Length of mount from bottom of angle to top of mount: 3.375" (85.7mm)
- 1/4-20 stud with lockring; adjustable at the camera (190° Tilt, 360° Turn & 360° Rotation)
- Knob and tamper-resistant set-screw adjusting options included. Matching vinyl cover adds a finished look!
See any errors on this page? Let us know.


text:
First off, "Immunity Night" had nothing to do with cold and flu season.
Instead, it was a new wrinkle added by the "Dancing With the Stars" producers so we don't get bored with the ballroom now that serial flasher Paula Deen and disoriented philosopher Gary Busey are gone.
What was it all about? Extra points and real-time voting and fan input and blah blah blah. Here's the important part: Dance off! Six couples met head-to-head in battle-arena "You Got Served"-style. (Not really. But they did have to go toe-to-toe, so to speak, while the "immune" couple looked on and tried not to be smug).


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"This card came out beautifully. I was able to use the portions of the photos that I wanted as well as enhance several smaller photos to make a bolder statement. The card's paper quality was excellent. One suggestion, I like to write a short note on the back of the cards. Because of the black base color of the card it would be extra nice if Tinyprints offered the purchase of a gold gel pen with the order."
"I know I rely on Tinyprints to deliver a quality product on time that is also beautiful. I love that I can edit so much of the card unlike other companies."
"Adorable card, just the right touch of whimsy, but the colors and design are simple enough that it doesn't overwhelm you. Just a beautiful, really sweet card."
"I used this card for a Happy New Year card with a black and white photo. Used the Pearl White Shimmer paper and the results were exceptional. Very happy with the final product!"
"I liked having so many New Year's card choices with tinyprints. The Snowflake Serenity card was best for the photo I had. Classic design that showcased the photo."


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- status: open --> closed
- assigned_to: Alexx83
Package mingw-w64-x86_64-libgcrypt depends on package mingw-w64-x86_64-libgpg-error, which installs its dll to /mingw64/bin/libgpg-error-0.dll:
pacman -Ql mingw-w64-x86_64-libgpg-error
mingw-w64-x86_64-libgpg-error /mingw64/bin/libgpg-error-0.dll
However the library installed by package mingw-w64-x86_64-libgcrypt (to /mingw64/bin/libgcrypt-20.dll) links to libgpg-error6-0.dll:
objdump -x /mingw64/bin/libgcrypt-20.dll | grep DLL
vma: Hint Time Forward DLL First
DLL Name: ADVAPI32.dll
DLL Name: KERNEL32.dll
DLL Name: msvcrt.dll
DLL Name: USER32.dll
DLL Name: libgpg-error6-0.dll
I ran into issues loading a library that depended on libgcrypt with an error of the following structure:
error while loading shared libraries: ?: cannot open shared object file: No such file or directory (the ? was actually present in the output)
but strace on the executable showed that the error was in fact the misnamed libgpg-error-0.dll
On my system, this was resolved easily by copying libgpg-error6-0.dll to libgpg-error-0.dll in /mingw64/bin/.
If there is any more information you need please let me know.
Thanks for report!
Now fixed. Try update packages.
Shane Peelar
Confirmed, it works! Thank you


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JPEG is an adjustable "lossy" compression method commonly used in digital photograph. The most common filename extensions for images using the JPEG format are .jpg and .jpeg. Compare to alternative image formats such as TIFF and the various RAW formats.
There is no tag wiki for this tag … yet!
Tag wikis help introduce newcomers to the tag. They contain an overview of the topic defined by the tag, along with guidelines on its usage.
All registered users may propose new tag wikis.
(Note that if you have less than 20000 reputation, your tag wiki will be peer reviewed before it is published.)


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Category Archives: Eating Disorders Videos
National Eating Disorders Week 2015 officially runs from February 22-28. I think that sometimes it is easy to blow this week off every year, because the reality is that we are at a point (at least in the United States), … Continue reading
Not a day goes by without me feeling grateful about being able to share with you on this blog my lived experience with an eating disorder. The concept of giving back to others who stand where I once stood makes … Continue reading
Very often, I'll come across guidelines explaining or offering guidance on what to say or not to say to someone suffering from an eating disorder. Though these guidelines are useful and important in order to give those who are not … Continue reading
Every day, I make small choices which greatly impact the maintenance of my bulimia recovery. One of these choices starts with thinking ahead in the morning on the meals I plan to have throughout the day; while another is being … Continue reading
Having a list (or shoebox) full of coping skills is awesome — if it's nearby when an urge strikes. So what happens when you're driving home after work? Or hanging out at the mall killing time? Those coping skills you … Continue reading
Lately, I've been thinking about the turning points I experienced in my eating disorder recovery, over the past 5 years. Ironically, one of the major breakthroughs I recently had, happened just this past Spring. I find it ironic, because up … Continue reading
Hey everyone! I wanted to share with you all a couple of letters that I wrote to my body, just to show you the progression towards body acceptance. In my last post, I talked a bit about the long road … Continue reading
Speaking out about having recovered from an eating disorder has been very rewarding to me. I have been getting involved with mental health related organizations in my community and I share aspects of my life as a person who has … Continue reading


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[They Asked For It LOUD!!!]
Hard Rock Mastering - 1 Sick Unit
1 Sick Unit Testimonial
"I have listen to all the tracks on various speakers and I feel you have done a fantastic job!!! I have followed your suggestion on mixing and am in the process of having the rest of the tracks remixed so everything has space, which should make the mastering process easier and better."
John Rogers, Big Label Sound Studio
This powerful rock cd came to us mainly lacking punch, clarity, and overall volume. Listen closely how muffled the "before" samples sound. We worked extensively with 1 Sick Unit to get the exact sound they were looking for. Clear, but hard sounding metal. We even gave suggestions on the mix so they could adjust it and achieve that sound.
We offer professional mixing and mastering here at Big Label Sound Mastering Studio. High quality work at an affordable price! You can also receive a FREE Mastering Demo, with no obligation.
Please Like Us on Facebook or share this with a friend!


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Representatives of the Attorney-General will appear before a joint parliamentary committee Friday to answer questions about plans to require Internet Service providers and other carriers retain data customer data for two years, The Australian reports. Meanwhile, Shadow Communications Minister Malcolm Turnbull is voicing his opposition to the proposed law. Meanwhile, a document recently released under freedom of information laws indicates that a preliminary privacy impact assessment of proposed reforms to the Telecommunications (Interception and Access) Act submitted to the Attorney General's Department last year recommended that a mandatory data retention regime be kept to a maximum of six months. (Registration may be required to access this story.)
Full Story
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Damn... this needs more views... 18 inches up the ass!
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Capital Markets
Company Overview of Timucuan Asset Management, Inc.
BOARD MEMBERS AFFILIATED WITH Russell Brown Newton III*
Founder and Chairman
MOST CONNECTED PEOPLE TO Russell Brown Newton III
|Richard Paul Schifter
|82 Relationships
|Robert J. Mylod
|44 Relationships
|Scott M. Stuart
|43 Relationships
|Gerald S. Armstrong
|24 Relationships
|Robert M. Clements
|23 Relationships
Sponsored Financial Commentaries
Sponsored Links
Only a company representative may request an update for the company profile. Documentation will be required.
To contact Timucuan Asset Management, Inc., please visit . Company data is provided by Capital IQ. Please use this form to report any data issues.
Our data partners will research the update request and update the information on this page if necessary. Research and follow-up could take several weeks. If you have questions, you can contact them at firstname.lastname@example.com.


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Book your room at Quality Inn Crestview / Ft. Walton
Standard Room, 2 Double Beds, Non SmokingMax Occupancy: 4 guests (up to 3 children, 2 infants)
Standard Room, 1 King Bed, Non SmokingMax Occupancy: 2 guests (up to 1 child, 1 infant)
Room, 1 King Bed, Non Smoking (Pet Friendly)Max Occupancy: 2 guests (up to 1 infant)
Room, 2 Double Beds, Non Smoking (Pet Friendly)Max Occupancy: 4 guests (up to 3 children)
Get an overview of this hotelHotel in Crestview with free breakfast and outdoor pool
Located in the heart of Crestview, this hotel is 3 mi (4.8 km) from Twin Hills Park and within 12 mi (20 km) of Hot Wheels Skating Center and Sasquatch Zoo. Chautauqua Vineyards and Lake Defuniak are also within 32 mi (52 km).
Hotel Features
This hotel features an outdoor pool, a 24-hour fitness center, and a 24-hour business center. Free WiFi in public areas and free self parking are also provided. Other amenities include a meeting room, a 24-hour front desk, and express check-out.
Room Amenities
All 55 rooms provide conveniences like refrigerators and microwaves, plus free WiFi and LED TVs with satellite channels. Pillowtop beds, coffee makers, and free weekday newspapers are among the other amenities available to guests.Information missing or incorrect? Tell us!Opens in a new window
Hotel Amenities
Hotel Amenities
Quality Inn Crestview / Ft. Walton features an outdoor pool and a 24-hour fitness center. Public areas are equipped with complimentary high-speed wireless Internet access. Business-related amenities consist of a 24-hour business center and a meeting room. Guests can enjoy a complimentary breakfast. Event facilities measure 300 square feet (27 square meters). This Crestview hotel also offers barbecue grills, a picnic area, and complimentary newspapers in the lobby. Onsite self parking is complimentary.
- 24-hour business center
- 24-hour fitness facilities
- 24-hour front desk
- Barbecue grill(s)
- Free newspapers in lobby
- Conference space size (feet) - 300
- Conference space size (meters) - 27
- Express check-out
- Free breakfast
- Free self parking
- Free WiFi
- Number of buildings/towers - 1
- Number of floors - 3
- One meeting room
- Outdoor pool
- Picnic area
- Total number of rooms - 55
Family Friendly Amenities
- Free Wi-Fi
- Microwave
- Outdoor pool
- Refrigerator
Available in all rooms: Free WiFi
Available in some public areas: Free WiFi
Free self parking
Room Amenities
- Air conditioning
- Coffee/tea maker
- Free toiletries
- Free weekday newspaper
- Connecting/adjoining rooms available
- Daily housekeeping
- Desk
- Free local calls
- Free WiFi
- Hair dryer
- Iron/ironing board
- Microwave
- Phone
- Pillowtop mattress
- Private bathroom
- Refrigerator
- Satellite TV service
- Shower/tub combination
Where to Eat
A complimentary breakfast is offered.
Nearby Things to Do
Recreational amenities at the hotel include an outdoor pool and a 24-hour fitness center.
To make requests for specific accessibility needs, complete the "Special or Accessibility Requests" section of "Trip Preferences" when you book your hotel.
- Accessible bathroom
- In-room accessibility
- Roll-in shower
Hotel Policies
Check-in time ends at 7 AM
Check-in time starts at 3 PM
Minimum check-in age is 21
Check-out time is 11 AM
Payment types
Children and extra beds
- Children are welcome.
Pets allowed
You need to know
Extra-person charges may apply and vary depending on hotel policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
No rollaway/extra beds available
No cribs (infant beds) available
Optional extras
- Pet fee: USD 20.00 per pet, per night
Hotel Name
- Quality Crestview Ft. Walton
- Quality Inn Crestview
- Quality Inn Crestview Ft. Walton
- Quality Inn Ft. Walton
- Quality Ft. Walton
We should mention
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.


text:
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Home >
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Do Yoga and Pilates
You are requesting that we remove a reader's review from the site.
If this is not what you want, please return to the listing page.
Re: Best donation based studio out there
Date: 10/21/10
By: naruto
A Review of: Do Yoga and Pilates
If you selected "factual error" or "other", please explain:
Indoor surfing, spinning
lovefests, a luxurious
pig-placenta facial, and more.
Copyright © 2016, New York Media LLC. All Rights Reserved.


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Play any type of Game at Y8.com. The biggest Game Collection to play free online. Flash, Unity 3D, Html5, Android, Java and Shockwave.
If the game freezes, just click inside it (games can get unresponsive if you click elsewhere on the page).
Pursued by a killer as you search for the artifacts you need to pay homage to a deity who will destroy him, you have to listen, run, and hide to stay alive in this freakish nightmare of a game made in just fourteen days. Though rough around the edges, its surreal style and great production values make it a fun time with the lights down and the sound up.


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Relaxing Stay in The Lovely Seaside Town of Enniscrone
The Ocean Sands Hotel • Sligo, Ireland
Escape Kit
- One- (£59) or Two-Night (£99) Stay for Two People in a Deluxe Double Room
- Daily Breakfast
- Main Course Each (Two-Night Stay Only)
- Welcome Drink Each (Overnight Stays Only)
- Late 1 p.m. Checkout
Co. Sligo is home to the famous Kilcullen's Seaweed Baths—a venue for people to unwind in hot, tranquil baths filled with natural extracts from the sea. The bath house is just a short walk from The Ocean Sands Hotel which sits proudly overlooking Enniscrone beach.
Sink into an overnight stay for two people for £59 (up to a £107 value), whilst an extended two-night stay is just £99 (up to a £187.30 value). The family-run beachfront property extends a warm welcome to guests seeking a splash of relaxation. Featuring sea views, the boutique-style hotel is ideally located to explore all that the area has to offer. Your bright, spacious double room comes complete with flatscreen TV and en suite.
Gaze out across Enniscrone beach from the Onyx Bar whilst you relax with an evening tipple. Afterwards guests staying two nights will enjoy a main course each in Jasper's Restaurant where the talented kitchen team serve excellent cuisine in a bright and stylish space with an amazing vista of Killala Bay and the Atlantic. Expect to find a fusion of Irish and continental flavours in a selection of mouthwatering dishes. Come morning you'll rise to a hearty breakfast certain to fill you up for a day of exploring.
Make a pilgrimage to the aforementioned Kilcullen's Bath House for a soothing afternoon in a piping hot sea weed bath—a sure way to ease any tension and nourish the soul. Ramblers can't miss the breathtaking Benbulben Mountain—that dramatic peak of limestone and shale that's earned itself a reputation as Ireland's Table Mountain. Come evening you could witness one of Enniscrone's amazing sunsets with a stroll along the beautiful 5km of dune-surrounded beach. On your final morning you can enjoy a late 1 p.m. checkout.
This Escape is for two people.
"The deep bay produces the wonderful sandy blue flag beach, a 5km stretch with safe bathing. There are two bathhouses with hot seawater, seaweed and steam. The Moy estuary which forms part of the bay is a popular haunt for game anglers."-- Discover Ireland
30 day money-back guarantee
Can't find the dates you want? Dog ate your passport? No worries. You have 30 days post-purchase to return your voucher, no questions asked.
the fine print
- Valid from January 1, 2014 - April 30, 2014
- 1 voucher is valid for 2 people (Option B must be used over consecutive nights)
- Limit 1 voucher per reservation; offer cannot be combined to extend stay
- Reservations required and subject to availability - stay must be completed by April 30, 2014
- Please call the hotel within 2 weeks of voucher purchase to help secure desired date
- Not valid on February 8, 14, 15 2014; March 7, 14, 15 2014; April 5, 11-26 2014; Bank Holidays
- Option A: Valid weekends only
- Option B: Valid 7 days a week
- Merchant cancellation/re-scheduling policy of 48 hours applies; voucher subject to forfeiture
- Deal based on double occupancy in a Deluxe Double Room; upgrades available subject to availability
- Children welcome, children in cots stay free of charge, children under 12 years incur a €10 per child per night supplement, paid direct to merchant
- Wifi available
- Voucher includes: One- (£59) or Two-Night (£99) Stay for Two People in a Deluxe Double Room, Daily Breakfast, Main Course with Two-Night option only and Welcome Drink (Overnight Stays Only)
- Welcome drink is a glass of wine or pint of draught beer only
- Check in 3pm; check out 1pm
- Steak excluded
- Valid for purchased voucher option only
- Not valid in conjunction with any other offer and cannot be applied towards existing reservations
- Deal price inclusive of VAT
- Subject to availability. Hotel may reserve some rooms for non-LivingSocial guests
- For information on any special assistance required including disabled access, please contact merchant directly prior to purchase if required
- Enjoy By date on this voucher cannot be validly extended without the express written endorsement of LivingSocial. Without such written endorsement, any offer by the merchant to extend the Enjoy By date cannot be honoured by LivingSocial in the event that the merchant defaults
- Call +353 (0)96 26700 for further information if required
- Other conditions apply • PAID AND PROMOTIONAL VALUES EXPIRES ON April 30, 2014 • PAID VALUE DOES NOT EXPIRE • PAID VALUE EXPIRES ON April 30, 2019 • PROMOTIONAL VALUE EXPIRES ON April 30, 2014 • Enjoy By April 30, 2014
Other conditions apply
Except where noted in the fine print:
• No cash value/cash back
• Service not included
• Merchant is responsible for the quality of the products or services provided to you at redemption
• Entire value must be used in one visit
• Cannot be combined with any other offer or promotion
• LivingSocial Terms and Conditions - https://www.livingsocial.com/terms
Original Price:
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Look through the small devices that were used by agents of KGB some dozens of years ago.
The gun fires cyanide ??……..that's very um ?? …….hmmm……??…….cyanide…….hmmm
I've never seen non-mp5k version of case gun before.
Not just for transport, isn't that gun-case also made to shoot the gun inside of it like mp5k's?
Whatever. Wasted money, time, lives. Preserve a forest and you've both progressed humanity and can use it to hide in (a la Antonov!). Although I've got no quarrel with the compass (that deserves a Lenin Prize).
Nice Stuff, thought some like tree branch was American not KGB, thought it was confiscated some time later, it was in example solar powered (BTW also it would be fun if someone write more back-story about). Also fastener dates from WWII well before KGB was formed. Nice devices actually.
My favorite is R2D2 listening device. Is this British or American??
I've got almost the same sleeve-buttons, but gadgetless
Guess the most famous KGB contraption is the umbrella used to murder the Bulgarian dissident. It was also used in a French comedy (starring Pierre Richard).
I can't help but wonder how many Soviet era women might have grabbed a cyanide laced lipstick by mistake? OOPS
glove gun -> isn't it british soe weapon?
Never, ever, leave James Bond alone, in a room, with a Russian spy/babe!!


text:
walk softly and carry a big gun.
I changed the helmet for the final pic to make it more night lordy, I think this one would have suited an Iron warrior a bit better
I changed the helmet for the final pic to make it more night lordy, I think this one would have suited an Iron warrior a bit better
He's got SOME firepower!
Yeah, was about to say it looks more iron warrior-dy
Mouth on the bolter would be closed and everytime it fires a distinct sound follows... Nom Nom Nom! :/
I'm reading Blood Reaver right now, and I'm just curious what you think The Exalted looks like. It kind of sounds like he would look like a shark, but ADB throws in a new hint of another permutation of his anatomy. I was particularly amused when he described him as having "jaws". I can only imagine him in the shadows making squishy gurgling noises as he slobbers from orifices in places I don't want to think about.
Facial detail on that heavy bolter (did that make sense?) is awesome.
Great pose and detail It's just annoying how your conceptual sketches are better than my finished products
they're really not dude, it's easy to see how much more work has gone into your pictures, the only reason I 'm getting the shapes down is because I've been drawing 40k hard for the past two years or so, you've obviously got the talent and the eye for detail just keep pupmpin the pics out dude, one thing that I really recommended is to get a cheap ass packet of printing paper from tescos, it's like about three quid, that way you get rid of the worry of having to 'use' the paper you have and you can just go nuts with sketches, designs, poses and all other types of things that'll get you to the level you want to be
Cheers for that bud Yeh I have a ton of sketch paper now, so scribbling a bit heh. Need to produce another proper drawing though, as I'm a bit behind Got a couple in the works...so hoping to see improvement
I actually like the sketches better than the finished pieces... Here the the expressions and details stand out far more, in the finished piece, the glossiness of the coloring is detracting from the level of attention that went into the poses and equipment.
Mercutian's "Bring it on" expression is pretty much absent from his full rendition... So glad you are putting these sketches up.
Mercutian's "Bring it on" expression is pretty much absent from his full rendition... So glad you are putting these sketches up.
cheers man, aye it's all part of the process dude, sometimes it's brutal drawing a picture then realizing that a butt load of what you've drawn is never goin' to go into the final piece or having to change designs because they just dont look right in 'that' particular stance, but I'm the anti-anal when it comes to my pictures dude, I know progression is halted by pining for lost ideas, that said I do love to doodle my ass of for prep work and when I get permission to chuck the sketches up it's really cool
One thing I love about Night Lords: they didn't have to change their appearance post-heresy. They already looked the part.
too true dude they don't give a shit what armour they use as long as it's dark, scary and spikey
Love the heavy bolter, the face on it looks great.
I love it, the level of detail fora conceptual sketch is awe inspiring
I'm especially impressed by the heavy bolter
I'm especially impressed by the heavy bolter


text:
First Performance in Brazil
Event Date: January 17, 2012
Posted: January 17, 2012
Views: 3607
Location: England, United Kingdom
In late 2009 I announced the 'arrival' of my then latest composition ('The Life of a Woman') - a cantata for Solo Soprano, Solo Cello, SATB Chorus and Strings. I also offered the piece to members of Choralnet. Two members took me up on the offer and one of them (Wagner Politschuck from Brazil) wanted to perform it with his Camerata Antiqua de Curitiba in Southern Brazil. I was delighted with the news and replied very positively to Wagner's e-mail. The performances were planned for 16/17/18 December 2010 in Capela Santa Maria in Curitiba.
A few days before I set off for Brazil, Wagner asked if I would like to conduct my piece. In spite of the lateness of the offer I accepted gladly. I had found out quite a bit about the choir and explored the internet for information about the orchestra. What I found was very positive. Both the choir and orchestra were full time professional musicians paid by the state. They rehearsed for up to two weeks prior to the concert 2-3 hours each day. My flight arrived on time on the 15th (the day before the first performance) and I was taken straight to the hall after 22 hours of travelling. Within 5 minutes of my arrival I was conducting my piece. Both the choir and orchestra were very receptive to my lead and helpful in taking direction very easily. The soprano soloist (Natalia Aurea from Sao Paulo) was excellent and understood her solo really well. The cello soloist (Faisal Hussein - a member of the orchestra) was superb. His playing gave the performances so much strength and depth of feeling.
After just one hour's rehearsal on the morning of the 16th, we performed the piece for the first time to a small but extremely appreciaitve audience that evening and on the Saturday and Sunday. The three performances went remarkably well. The atmosphere at all times was friendly and welcoming. But more importantly I was a part of a program more or less devoted to the music of contemporary composers, mainly from Brazil. I met Liduino Pitombeira, a brilliant composer from Brazil, who has since become one of my firm friends. He is a teacher to earn a living but a composer with an impressive array of titles out of choice. Liduino wrote a beautiful commission for the concert called 'Acordes Poeticos'.
From a simple post on Choralnet, I ended up travelling over 6000 miles to conduct the premiere performance of my cantata. But more than that I have made significant friends with whom I am in regular contact. Choralnet can at times seem a little mundane. It will never be that way for me living in England. To have made contact in such a way, and to have received such magnificent friendship from so many wonderful musicians is something I shall never forget. Couple that with the opportunity of excellent performances of my 30 minute cantata and you have the reason why Choralnet is so important.
If anyone is interested in hearing 'The Life of a Woman' and/or a copy of the score in pdf, please contact me at email@example.com.
Thanks for taking the trouble to read this piece. It means a great deal to me!
Stuart McIntosh


text:
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text:
This is an interview question I saw from here: http://www.careercup.com/question?id=1707701
Want to know more about this .thanks
This is an interview question I saw from here: http://www.careercup.com/question?id=1707701
Want to know more about this .thanks
closed as not a real question by bmargulies, Tim Post♦ Mar 12 '11 at 1:14
It's difficult to tell what is being asked here. This question is ambiguous, vague, incomplete, overly broad, or rhetorical and cannot be reasonably answered in its current form. For help clarifying this question so that it can be reopened, visit the help center.If this question can be reworded to fit the rules in the help center, please edit the question.
Shallow copy causes a problem (primarily) when you have "remote ownership". The most common form is a pointer to data that's owned by the object so when the object is destroyed the data it owns gets destroyed as well. One place many people run into this is the inevitable string class:
This will compile just fine. Under these exact circumstances, it might even seem to run fine as well. That doesn't mean it's really right though. When we assign
There are two common alternatives to shallow copying. One is a "deep" copy, in which we overload the copy constructor and assignment operator for the class, and in them when we copy/assign the object, we allocate a new buffer and copy the contents of the old buffer to the new one.
The second is reference counting. Instead of a "raw" pointer to the buffer, we use a "smart" pointer to the buffer. The smart pointer keeps track of how many objects refer to the buffer and only frees the buffer itself when nothing refers to it any more.
Neither is entirely perfect: deep copying can be slow and use a lot of memory, especially if there's a lot of data involved. Reference counting can be slow in multi-threaded environments -- since the reference count can be accessed from multiple threads, you have to protect it to assure only one thread modifies it a time (which is usually at least an order of magnitude slower than a normal increment/decrement).
shallow copy is when you just make a copy of an object with exactly the same fields(and pointer):
the class
so now we copied all fields of car1 to car2 and both of them fields owner pointing to same owner, and since owner it's a pointer we are now have a dangling pointer so each change made in car1 will affect car2
but if we would made a deep copy we should get it right:
so now changes on car1 won't affect car3 at all
HERE is an explanation with images
Wikipedia has a good introduction


text: I am blessed to be in a very creative and talented family. My dad is a full time artist (and has been since 1979), I am a full time nature / cowboy photographer, my youngest brother is a film maker and professor of video at a college in Washington State. Our middle brother is a a farrier and horse trainer as well as being a very talented musician and singer. Charley, (my youngest brother) made this video of Tommy plying his trade. I am hoping to have him do a video of him horse training as well. Charley is really an artist with his films and has won many awards! Enjoy and let me know what you think!


text:
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Melchior Pfintzing (1481-1535)
Theuerdank 1517
Printed on vellum, with hand-coloured illustrations | 39.2 x 27.5 cm (book measurement (conservation)) | RCIN 1050719
Melchior Pfintzing (1481-1535)
Die Geuerlicheiten und Einsteils der Geschichten des loblichen streitbaren und hochberumbten Helds und Ritters Tewrdannckhs 1517
Melchior Pfintzing (1481-1535)
Die Geuerlicheiten und Einsteils der Geschichten des loblichen streitbaren und hochberumbten Helds und Ritters Tewrdannckhs 1517
Melchior Pfintzing (1481-1535)
Die Geuerlicheiten und Einsteils der Geschichten des loblichen streitbaren und hochberumbten Helds und Ritters Tewrdannckhs 1517
White pigskin binding with blind tooling and King George V monograms on both boards; King George V armorial bookplate inside front board. Maximilian I prepared a trilogy of autobiographical books - 'Weisskönig' ('The White or Wise King'), 'Theuerdank' ('Precious Thanks') and 'Freydal' ('The Joyful One') - which he intended to act as a literary memorial to his own life and reign. Of these three works, only 'Theuerdank' was completed during his lifetime; about 40 copies were printed on vellum (several of which were coloured and illuminated) and 300 copies on paper, for presentation to the Emperor's friends. 'Weisskönig' told the story of Maximilian's youth, while 'Theuerdank' recounted Maximilian's dangerous and heroic adventures in 1477 on his journey to claim his bride Mary of Burgundy, daughter and heir to the ruler of Burgundy, Charles the Bold. The story was deliberately allegorical in form, and told as if it were a medieval Arthurian romance, written in rhyming couplets. A key was provided at the end of the work to inform the reader of the real identity of the main characters: the knight Theuerdank (Maximilian) journeys to claim his bride Ernreich (Rich in Honour; Mary) after the death of her father Romreich (Rich in Fame; Charles), accompanied always by his faithful squire Ernhold (Steadfastly Honoured), who is depicted with the wheel of fortune on his tunic. Their journey is constantly harried by three captains of Ernreich who wish to prevent the match - Fürwittig (Over-confident), Unfalo (Unlucky) and Neydlhart (Envious) - and who are interpreted as the dangers of the three ages of man, Youth, Maturity and Old Age. Despite their very best efforts, Theuerdank reaches his bride, executes his three enemies and is finally sent off on a crusade to prove beyond all doubt his worthiness as a knight of Christendom. The outline for the story was dictated by Maximilian c 1505-8, and its text was edited and prepared for publication by his secretary Melchior Pfinzing. By about 1513 it was ready to go into production in Augsburg, under the direction of Conrad Peutinger (1465-1547), who was essentially Maximilian's literary agent. Augsburg was important both as the seat of the Imperial Council and as a centre for German printing and high-quality craftsmanship. It was also home to Hans Schönsperger, who had been given a lifelong appointment as Maximilian's imperial printer in 1508. Schönsperger designed the Fraktur type used in 'Theuerdank', based on a manuscript original; and to increase the illusion of a manuscript, a series of separate flourishes was cut to add to the letterforms. Peutinger assembled a formidable team of artists to design the 118 illustrations, notably Hans Burgkmair (1473-1531), Hans Schäufelein (1482/3-c 1540) and Leonhard Beck (c 1480-1542), and engaged the expert block cutter Jost de Negker (c 1485-c 1544) to oversee the cutting of the woodblocks. The illustration seen here, showing Unfalo endangering Theuerdank while firing a cannon, was designed by Schäufelein, whose signature H with a little spade ('Schäufelein' means 'little spade') appears in the bottom right-hand corner of the image. Catalogue entry adapted from 'The Northern Renaissance. Dürer to Holbein', London 2011.
ProvenanceProbably acquired for the Royal Library by 1860
People involved
Creator(s)Search the collection
Melchior Pfintzing (1481-1535) (author)Search the collection
Maximilian I, Holy Roman Emperor (1459-1519) (contributor)Search the collection
Hans Burgkmair (1473-1531) (illustrator)Search the collection
Leonhard Beck (c. 1480-1542) (illustrator)Search the collection
Hans Schäufelein (1482/3-c. 1540) (illustrator)Search the collection
Jost de Negker (c 1485-c 1544) (engraver)Search the collection
Conrad Peutinger (1465-1547) (contributor)Search the collection
Nuremburg : Schönsperger (publisher)
Subject(s)Search the collection
Physical properties
Medium & Techniques
Printed on vellum, with hand-coloured illustrations
39.2 x 27.5 cm (book measurement (conservation))
- Groupings
Alternative titles
Die Geuerlicheiten und Einsteils der Geschichten des loblichen streitbaren und hochberümbten Helds und Ritters Tewrdannckhs.


text:
realmagick.com The shrine of knowledge.
A selection of articles related to seek.
Original articles from our library related to the Seek. See Table of Contents for further available material (downloadable resources) on Seek.
- I am Pagan
- I am Pagan. I am a part of the whole of Nature. The Rocks, the Animals, the Plants, the Elements, and Stars are my relatives. Other humans are my sisters and brothers, whatever their races, colors, genders, sexual orientations, ages, nationalities, religions,...
Religions >> Paganism & Wicca
- Survivalists' Guide for the New Millennium: Chapter 4
- THE TRANSFORMATION OF CATERPILLAR TO BUTTERFLY It is not difficult to see that the whole Agenda behind owning a bigger home, a newer car and more land is one of ego. This is an orientation toward the building of an empire of material wealth, in a vain...
Philosophy >> Survivalists Guide for the New Millennium
- The Crystallization of Truth
- There exists One Indivisible Truth , around which all other concepts and systems revolve. Around this central Sun of Reality, every philosophy, religion and social ideal orbits without fail. The search for this essential essence has been a primary focus...
Religion & Philosophy >> Philosophy
- Manifesting World Enlightenment: Part 5
- All things in the universe have at their basis, one fundamental essence which governs their creation, destruction and on-going actions. That singular essence is consciousness, (also known by some as God, or the Unified Field). Everywhere in Nature does...
Mind >> World Mind
- Software of the Mind #2: Adopting Natural Software
- Connection with Nature faded away as humanity removed itself physically and mentally from natural living. Thought replaced direct knowledge, (intuition) and ego replaced the mode of the natural mind. This is becoming increasingly the case not only at the...
Mystic Sciences >> Mind
- Principles of Wiccan Belief
- In the spring Witchmeet held April 1974 in Minneapolis, Minnesota, The Councel of American Witches adopted this statement entitled "The Principles of Wiccan Belief." The statement was created in hopes to bring awareness to the general public as well...
Religions >> Paganism & Wicca
- Survivalists' Guide for the New Millennium: Chapter 5
- WHERE I LAY MY HEAD IS HOME A foot and light-hearted I take to the open road, Healthy, free, and the world before me, The long brown path before me leading Wherever I choose. Henceforth I ask not for good fortune, I myself am good fortune, Henceforth I...
Philosophy >> Survivalists Guide for the New Millennium
Seek is described in multiple online sources, as addition to our editors' articles, see section below for printable documents, Seek books and related discussion.
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- H1N1 Symptoms - When to Seek Medical Care
- H1N1 Symptoms -. When to Seek Medical Care.
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- Seek & Destroy: How to identify entrepreneurial obstacles and overcome them. © Copyright 2010 Peter Shallard. All Rights Reserved.
- www.petershallard.com
- Hide and Seek: An Introduction to Steganography
- Hide and seek. Although steganography is applicable to all data objects that contain redundancy, in this article, we consider.
- niels.xtdnet.nl
- What You Seek is What You Get: Extraction of Class Attributes from
- What You Seek is What You Get: Extraction of Class Attributes from Query Logs. Marius Pasca. Google Inc.
- www.cs.jhu.edu
- Diligently seek out subjects of news stories to give them the opportunity to respond to allegations of wrongdoing. ▶ Identify sources whenever feasible.
- www.daily-journal.com
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- As the potential loomed for enormous damage from Hurricane Irene, the White House said Friday US President Barack Obama had told aides he would cut short his vacation and return to the US capital.
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- Specializes in assignment (temporary) and direct hire (permanent) positions in office clerical, light industrial, skilled technical and professional disciplines.
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- Seek - Definition and More from the Free Merriam-Webster Dictionary
- to resort to : go to. 2. a : to go in search of : look for b : to try to discover.
- www.merriam-webster.com
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text:
November 06, 2013
The 2013 North American NGV Conference and Expo will be held at the Georgia World Congress Center Nov. 18–21 in Atlanta, Ga. The three-day event will feature a conference, a large exposition hall and numerous social functions.
The conference will feature off-site technical tours of nearby facilities and a mix of over 75 presentations, panel discussions and breakout sessions addressing pertinent NGV-related topics. Some conference speakers include:
The 75,000 square-foot exposition hall will house more than 100 exhibitors showing the latest in light, medium and heavy duty vehicle platforms, fuel station technology and service providers, and others involved in market development. Attendees will consist of fleet operators, policy makers and various NGV industry stakeholders.For more information on the 2013 North American NGV Conference and Expo, or to plan your attendance, visit the event website at http://cleanvehicle.org/conference/2013.
We offer e-newsletters that deliver targeted news and information for the entire fleet industry.
The expert, Mark Betner from CITGO, will answer your questions
Visi-Chek Shows Out of Compliance Brake Strokes
Vacuum Equipment Available on Ford and Freightliner Chassis
Alignment Tool Uses Camera-Based Tech
SimpleCheck Tool Identifies Out-of-Adjustment Brakes


text:
Portland Fruit Beer Festival
Saturday June 9th - Sunday June 10th
Pre-Fest Home-Brewers Dinner (Friday Only)
Friday, June 8, 2012 at 6:00pm
The Portland Fruit Beer Festival returns bigger and badder in 2012 (June 9th and 10th) after unprecedented success in it's first year outside of Burnside Brewing Co. The only festival of it's kind the PFBF celebrates the wonderful, creative and uniquely crafted fruit beers of the Pacific NW and beyond. Once fruit beers were a staple of every brewery but when quality product became harder and harder to obtain at cheap prices many breweries stopped making them or turned to cheap extract flavorings which in turn helped to give fruit beers a bad name in the craft beer community.
The Portland Fruit Beer Festival is bringing back the tradition with an outstanding lineup of the best fruit beers the world has to offer, many of them brewed specifically for this festival by local brewers. 25 different breweries are sending entries into this years festival with another 20-30 special rare one-off kegs for our rotating taps that will change throughout the festival.
As part of the festival we are holding a Fruit Beer Homebrewing Competition with the Oregon Brew Crew open to anyone to enter. Winners of 4 categories and one overall winner will get gift certificates to Burnside Brewing. All entries are also eligible to have their beer poured at the first ever Fruit Beer Fest Homebrewers Dinner on Friday June 8th in Burnside Brewing Co.'s south brewery. This catered dinner will have 4 of the best fruit beers by homebrewers entering the competition on tap as well as professional brewers on hand to speak about brewing with fruit.
For more info on the Homebrew competition and dinner go here.
We will be welcoming back some of the finest mobile food providers that we had last year: Tastebud and 50 Licks ice cream and the addition of mobile cart PBJ's Grilled who will be designing a special sandwich to pair with the fruit beers. Juice and snacks will be available for those under 21 at this all-ages festival.


text:
Caffe Bene
60 Second Review: Caffe Bene
A quick update for Caffe Bene – which opened up recently downtown on Hudson Street.
For starters, the place is intelligently laid out, with nice earth-tone decor and comfortable seating.
The coffee definitely was a step up from diner java – and my friend who tasted the gelato said it was quite good. The other "treats" on the menu were quite expensive for a fast-food type coffee-shop / chain – but I suppose they're worth it, as customers were buying them (how long that lasts before the novelty wears off remains to be seen.) The sandwiches appeared to be in the reasonably-priced range (although much more than Subway).
Judging by the weekday traffic in the middle of the afternoon – I'd venture to guess that Caffe Bene will survive. The staff was a bit lethargic with an apparent "bare minimum effort" mentality (albeit cordial enough). Not sure if that was because they are "still learning," or that we have an entire generation of clueless idiots about to hit the service-industry workforce.
How this impacts local coffee places that also opened (like Bean Vault) is unknown. But Caffe Bene is in a very strategic spot, and considering that Dunkin' Donuts around the corner has terrible QC issues (and horrible coffee) certainly won't hurt.
Description: South Korean coffeehouse modeled after European Coffeehouses, located here in America.
Address: 79 Hudson Street, Hoboken, NJ 07030
Phone: 212-575-5484
Email: email@example.com
Online: caffebeneusa.com
Caffe Bene | 79 Hudson St. | Hoboken, NJ
Opening soon at 79 Hudson Street (formerly Halstead Property) is Caffe Bene.
Caffe Bene is a coffee chain that originated from South Korea (in 2008), and has been "exploding" on the US market since 2012 (currently over 1300 stores worldwide).
"Caffe Bene is the leading franchise in the South Korean coffee market. We've modeled ourselves on the traditional European coffeehouse. Caffe Bene is a destination for rest and relaxation amid the more hectic scenes of city living. Through our coffee and delectable food items, we offer satisfaction in its simplest form."
Hmm. A South Korean "model" of a "European" coffeehouse. So it doesn't really matter where they're from or what they're "modeling," right? Isn't that the same as saying "we're copying someone else?" Or "our idea wasn't good enough, so we took an existing one?" Or "our crappy pizza was no good, let's copy the brick oven place two doors down?" (the last one was an actual Hoboken example…)
Anyway, I guess all the "original" ideas have been used up, and everything from now going forward will be a replication. (At least they attributed their source!)
They'll serve waffles, gelato, coffee and other "sweet treats," along with brunch and baked goods. As you can see above, their "uniforms" are almost a flashback to the 70's! (Although the two guys in the middle have that "rather be elsewhere" look on their faces…")
Regardless what I mentioned above, the company does seem like a pretty fun place to work, and the owner appears to be the "straight-forward type" businessman. Perhaps that's why they're successful at the rapid expansion. Either way – good luck to Caffe Bene, and may the place remain occupied for at least five years!


text:
Are you Jennifer L Pauley?Claim your profile
Publications (10)29.24 Total impact
Article: Sequential administration of methotrexate and asparaginase in relapsed or refractory pediatric acute myeloid leukemia[Show abstract] [Hide abstract]
ABSTRACT: Background: The efficacy of combination chemotherapy with methotrexate (MTX) and asparaginase is not well known in relapsed and refractory acute leukemia after contemporary therapy. Procedure: A retrospective study of pediatric patients with relapsed or refractory acute myeloid leukemia (AML) who received MTX and asparaginase as a salvage therapy at St. Jude Children Research Hospital was performed. MTX was given intravenously followed by a dose of asparaginase intramuscularly or intravenously 24 hours later. The chemotherapy cycle was repeated every 7-10 days. Response, survival, and toxicities were evaluated. Results: Fifteen patients, median age 10.5 years (range, 1.1-18.5 years), were treated. Median number of previous therapeutic regimens was three (range, 1-4). Six patients responded to treatment (three had morphologic complete remission with incomplete blood count recovery, two had partial remission, and one had stable disease for 16 months), and four are still alive. Three of six responders had monoblastic leukemia, and also developed tumor lysis syndrome. The 1- and 2-year overall survival rates are 35.6% and 17.8%, respectively. The most common adverse event was transient elevation of transaminases (nine patients). Two patients developed pancreatitis. Episodes of febrile neutropenia were rare (two patients), and most courses (75 out of 93 total courses) were given in an outpatient setting. Conclusions: Combination chemotherapy with MTX and asparaginase appears to be an effective salvage therapy and well tolerated in patients with relapsed or refractory childhood AML, even in those heavily pretreated with contemporary frontline or salvage therapy.
Article: Erratum to: Between-course targeting of methotrexate exposure using pharmacokinetically guided dosage adjustments[Show abstract] [Hide abstract]
ABSTRACT: Purpose: It is advantageous to individualize high-dose methotrexate (HDMTX) to maintain adequate exposure while minimizing toxicities. Previously, we accomplished this through within-course dose adjustments. Methods: In this study, we evaluated a strategy to individualize HDMTX based on clearance of each individual's previous course of HDMTX in 485 patients with newly diagnosed acute lymphoblastic leukemia. Doses were individualized to achieve a steady-state plasma concentration (Cpss) of 33 or 65 μM (approximately 2.5 or 5 g/m(2)/day) for low- and standard-/high-risk patients, respectively. Results: Individualized doses resulted in 70 and 63 % of courses being within 20 % of the targeted Cpss in the low- and standard-/high-risk arms, respectively, compared to 60 % (p < 0.001) and 61 % (p = 0.43) with conventionally dosed therapy. Only 1.3 % of the individualized courses in the standard-/high-risk arm had a Cpss greater than 50 % above the target compared to 7.3 % (p < 0.001) in conventionally dosed therapy. We observed a low rate (8.5 % of courses) of grade 3-4 toxicities. The odds of gastrointestinal toxicity were related to methotrexate plasma concentrations in both the low (p = 0.021)- and standard-/high-risk groups (p = 0.003). Conclusions: Individualizing HDMTX based on the clearance from the prior course resulted in fewer extreme Cpss values and less delayed excretion compared to conventional dosing.
Article: Posaconazole Therapeutic Drug Monitoring in Pediatric Patients and Young Adults with Cancer (July/August).[Show abstract] [Hide abstract]
ABSTRACT: BACKGROUND:Limited information exists regarding the use of posaconazole for treating systemic fungal infections in children, adolescents, and young adults with cancer. At St. Jude Children's Research Hospital, the recommended posaconazole dose in patients weighing less than 34 kg is 18-24 mg/kg daily, given in 4 divided doses. For patients aged 13 years or older or those weighing 34 kg or more, the recommended dose is 800 mg daily, given orally in 4 divided doses.OBJECTIVE:To determine whether the current posaconazole dosing guidelines achieve target posaconazole plasma concentrations of 0.7 μg/mL or greater.METHODS:This retrospective clinical study examined data from patients who received treatment-dose posaconazole and had at least 1 posaconazole plasma concentration measurement.RESULTS:Data from 33 patients who received posaconazole for the treatment of fungal infections were analyzed. The median age of patients was 11.5 years (range 0.5-23.2). Twenty-one of 33 patients (63.6%) had posaconazole concentrations of 0.7 μg/mL or greater (median 1.4; range 0.7-2.98) at the first measurement. The median posaconazole dosage referenced to total body weight in these patients was 20 mg/kg/day. Patients with concentrations less than 0.7 μg/mL (median 0.4; range 0.025-0.69) received lower posaconazole dosages when referenced to body weight (median 12.9 mg/kg/day; p = 0.02). Of the 12 patients with concentrations less than 0.7 μg/mL, 7 (58.3%) were aged 13 years or older.CONCLUSIONS:The current dosing approach for posaconazole yielded therapeutic plasma concentrations more frequently in patients younger than 13 years than in those 13 years or older. This difference may be related to the practice of capping adolescent and young adult doses at the suggested maximum adult daily dose. Therefore, we recommend weight-based dosing in all pediatric, adolescent, and young adult patients with cancer, with routine therapeutic drug monitoring to ensure adequate concentrations.
Article: Resumption of high-dose methotrexate after acute kidney injury and glucarpidase use in pediatric oncology patients[Show abstract] [Hide abstract]
ABSTRACT: High-dose methotrexate (HDMTX)-induced acute kidney injury is a rare but life-threatening complication. The methotrexate rescue agent glucarpidase rapidly hydrolyzes methotrexate to inactive metabolites. The authors retrospectively reviewed glucarpidase use in pediatric cancer patients at their institution and evaluated whether subsequent resumption of HDMTX was tolerated. Clinical data and outcomes of all patients who received glucarpidase after HDMTX administration were reviewed. Of 1141 patients who received 4909 courses of HDMTX, 20 patients (1.8% of patients, 0.4% of courses) received 22 doses of glucarpidase. The median glucarpidase dose was 51.6 U/kg (range, 13-65.6 U/kg). At the time of administration, the median plasma methotrexate concentration was 29.1 μM (range, 1.3-590.6 μM). Thirteen of the 20 patients received a total of 39 courses of HDMTX therapy after glucarpidase. The median time to complete methotrexate excretion was 355 hours (range, 244-763 hours) for the HDMTX course during which glucarpidase was administered, 90 hours (range, 66-268 hours) for the next HDMTX course, and 72 hours (range, 42-116 hours) for subsequent courses. The median peak serum creatinine level during these HDMTX courses was 2.2 mg/dL (range, 0.8-9.6 mg/dL), 0.8 mg/dL (range, 0.4-1.6 mg/dL), and 0.6 mg/dL (range, 0.4-0.9 mg/dL), respectively. One patient experienced nephrotoxicity upon rechallenge with HDMTX. Renal function eventually returned to baseline in all patients, and no patient died as a result of methotrexate toxicity. The current results indicated that it is possible to safely resume HDMTX therapy after glucarpidase treatment for HDMTX-induced acute kidney injury.
- [Show abstract] [Hide abstract]
ABSTRACT: Improved cure rates for childhood acute lymphoblastic leukemia (ALL) over the past 2 decades have allowed greater attention to patients' quality of life. Neuropathic pain (NP) is an unpleasant side effect of chemotherapeutic agents for leukemia, especially vincristine. We retrospectively reviewed the records of 498 patients treated on a single protocol for ALL to investigate the risk factors, the incidence, and the use of therapeutic and prophylactic gabapentin treatment for NP. White non-Hispanic race was the only patient variable predictive of NP. One hundred and seventy-four of 498 patients (34.9%) experienced 207 episodes of NP; 16% (28 of 174) patients experienced at least one recurrence of pain after the initial episode. No statistical significance was found in the relation between the severity (grade) of the NP episode and the cumulative dose of vincristine (P = 0.45) or the vincristine dose that immediately preceded the diagnosis (1.5 mg/m(2) versus 2.0 mg/m(2) [correction made here after initial online publication], P = 0.59). Of 180 episodes with treatment data, 62.2% (112) and 37.8% (68) were treated with gabapentin or opioids, respectively. The selection of treatment with gabapentin or opioids was not influenced by the pain intensity score at the time of diagnosis of NP (P = 0.91). The mean gabapentin dose used for 112 episodes was 15.5 mg/kg/day (SD 7.9). We found no evidence that gabapentin prevented recurrence of NP. Our results highlight the need for prospective randomized studies to elucidate the value of gabapentin regimen for prevention or treatment of vincristine-related pain during treatment of childhood leukemia.
Article: Combination chemotherapy with clofarabine, cyclophosphamide, and etoposide in children with refractory or relapsed haematological malignancies
Article: Recurrent Intrathecal Methotrexate Induced Neurotoxicity in an Adolescent With Acute Lymphoblastic Leukemia: Serial Clinical and Radiologic Findings[Show abstract] [Hide abstract]
ABSTRACT: Systemic and intrathecal methotrexate (MTX) are integral components of acute lymphoblastic leukemia (ALL) therapy, but can be associated with neurotoxicity. We describe here the case of an adolescent male with T-cell ALL who developed recurrent episodes of subacute neurotoxicity characterized by slurred speech, emotional lability, and hemiparesis after intrathecal MTX administration. Serial magnetic resonance imaging with diffusion-weighted imaging showed recurrent areas of restricted diffusion within cerebral hemispheric white matter, which correlated chronologically with the administration of intrathecal therapy and severity of clinical symptoms. Resolution of diffusion abnormalities did not preclude further toxicity and a large lesion could cause persisting symptoms.
Article: Effect of Allopurinol Versus Urate Oxidase on Methotrexate Pharmacokinetics in Children With Newly Diagnosed Acute Lymphoblastic Leukemia[Show abstract] [Hide abstract]
ABSTRACT: Allopurinol and urate oxidase are both effective in preventing or treating hyperuricemia during remission induction therapy for lymphoid malignancies, but to the authors' knowledge, their effects on concomitant anticancer drug therapy have not been compared. The authors compared plasma methotrexate pharmacokinetics in pediatric patients with newly diagnosed acute lymphoblastic leukemia who received concomitant allopurinol (n = 20) versus those treated with nonrecombinant or recombinant urate oxidase (n = 96) during high-dose methotrexate administration before conventional remission induction therapy. The minimum plasma concentration of uric acid was significantly (P < .0001) lower after urate oxidase treatment than the concentration after allopurinol treatment. Methotrexate clearance was significantly higher (median, 117.1 mL/minute/m(2) vs 91.1 mL/minute/m(2); P = .019) in patients who received urate oxidase. A higher proportion of patients in the allopurinol group had elevated methotrexate plasma concentrations (36% vs 7%; P = .003) and experienced mucositis (45% vs 16%; P = .003) after methotrexate treatment compared with the urate oxidase group. The lower rate of methotrexate clearance in patients who received allopurinol likely reflected a less potent hypouricemic effect of allopurinol, leading to precipitation of uric acid in renal tubules. Hence, during remission induction therapy for lymphoid malignancies, the authors concluded that renally excreted drugs should be monitored closely, especially in patients who are receiving allopurinol.
Conference Paper: Plasma voriconazole levels in pediatric patients and potential application to therapeutic drug monitoring[Show abstract] [Hide abstract]
ABSTRACT: Purpose: Therapeutic drug monitoring (TDM) may be useful to optimize voriconazole therapy, but no consensus exists regarding the therapeutic range. Data on voriconazole pharmacokinetics and TDM in children is limited. We evaluated the pharmacokinetics of voriconazole in pediatric cancer patients and explored the potential application of voriconazole TDM. Methods: Plasma voriconazole levels, patient demographics, indication, and other data were retrospectively collected from patients who received voriconazole between June 2004 and November 2007. Pharmacokinetic parameters, including clearance and area under the curve (AUC), were calculated for patients with three data points available (trough, peak, and 6-hr postdose). Results: Plasma voriconazole levels (60 trough, 29 peak, 11 random, and 29 6-hr postdose samples; total 129) from 48 patients (3 months to 20 years) receiving voriconazole as either prophylaxis (n=29) or treatment (n=19) were evaluated. The median (range) trough level was 0.25 (<0.2-10.00) µg/mL. Median dosage was higher in patients receiving voriconazole for treatment of an infection (4.3 mg/kg, 1.6-13 mg/kg) vs. those receiving prophylaxis (3.8 mg/kg, 2.2-5.7 mg/kg; p=0.014). However, median trough level did not differ in treatment group (<0.2, <0.2-8.4 µg/mL) vs. prophylaxis group (0.40, <0.2-10.00 µg/mL; p=0.19). When trough levels were stratified by age, the median trough level in patients less than 6 years old (<0.2 µg/mL, <0.2-10.00 µg/mL; n=34), was lower than that in older patients (0.62 µg/mL, <0.2-8.4 n=26; p=<0.001). For patients receiving IV voriconazole in whom PK parameters were calculated (n=6), the median clearance was 0.18 L/hr/kg and the AUC(0,12) was 25.54 mg*hr/L, which is comparable to published values. Conclusions: Voriconazole trough levels were frequently undetectable in this cohort of patients. Patients less than 6 years old demonstrated lower median trough levels and may require more frequent dosing of voriconazole. TDM may have a role in optimizing voriconazole therapy, particularly for patients less than 6 years old.
- [Show abstract] [Hide abstract]
ABSTRACT: Pleural effusions, ascites, and renal dysfunction decrease the plasma excretion of methotrexate (MTX). However, it is not known what effect these complications have on MTX clearance when they arise after the plasma MTX concentration has fallen to an undetectable level. We describe the clinical course and pharmacokinetics of MTX in a patient with acute lymphoblastic leukemia who experienced pleural effusions, ascites, and renal failure during the weeks after treatment with high-dose MTX (1.63 g/m2 i.v. over 24 h). The patient's normal initial MTX clearance rate (107 ml/min/m2) was consistent with his undetectable plasma level of MTX on day 9 after the infusion. His plasma MTX concentration then gradually increased as his renal function declined, reaching a peak of 0.72 microM on day 15. This unusual finding of an undetectable plasma MTX concentration that subsequently rose to persistent, potentially toxic levels was explained only by a pharmacokinetic model that accounted both for a third space at the time of treatment and for the subsequent decrease in the systemic elimination rate. Therefore, the finding of a physiologic third space during MTX administration combined with the detection of renal dysfunction in the following weeks should be an indication for prolonged therapeutic drug monitoring.
Top Journals
St. Jude Children's Research Hospital
Memphis, Tennessee, United States
- Department of Pharmaceutical Sciences
The University of Tennessee Health Science Center
Memphis, Tennessee, United States
- Department of Pharmaceutical Sciences


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|UI researchers identify genes that contribute to cleft palate
|News Releases - Health, Medicine & Nutrition
|Written by Hawkeye Caucus
|Friday, 13 July 2012 12:30
Investigators at the University of Iowa have identified the genes that contribute to cleft palate as one focal point of ongoing research that has remained active for more than 20 years. Advances in DNA analysis in recent years have enabled these researchers to identify several genes that cause rare, highly inheritable forms of cleft as well as about 10 genes that contribute to the common forms of cleft.
As part of this research, investigators have also found that some of the same genes appear to affect how some wounds of all types—the cleft is a kind of an embryonic wound—might heal, which has implications for trauma and surgical treatments.
Finally, researchers are also using three-dimensional facial imaging to determine how the normal face develops.
Jeffrey Murray, M.D., professor of neonatology and genetics at UI Carver College of Medicine and professor of biological sciences, dentistry and epidemiology in the College of Public Health: "These findings provide immediate benefits in finding new pathways in facial development and hold the promise for improving diagnosis and treatment. … All of this work has benefitted from the active participation of many families from Iowa who contribute freely to the research to benefit others."
Approximately one in every 1,000 babies born in the United States is affected by a cleft palate, a cleft lip or both, making the condition the most common birth defect in the country.
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posted 7 years ago
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Double jogging stroller that will fit my kids?
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I have a Baby Trend Skylar double jogger. I ordered it online from Wal-Mart. I bought it based on the single that I have of the same model. DS is 3 and big for his age so the straps don't go over his shoulders but I can still buckle him in at the waist. The seats sit up and lay down nicely but there isn't a snack tray ( I think you can order it) but there are mesh pockets to hold sippy cups.
DS's feet, at least one of them, tends to hang off the side but he likes to lean out of the stroller so that's more the reason. Here's a link to the one that I have and love. I even take my kids to runs with me. We've done several 5k's and a 10k and the stroller still is like new.
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Daniel 3:17New International Version (NIV)
17 If we are thrown into the blazing furnace, the God we serve is able to deliver us from it, and he will deliver us[a] from Your Majesty's hand.
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mugshot, mugshots.com news, mugshot news, editorials, opinion, mugshots
Jeffrey Allen Dean
Who is Jeffrey Allen Dean? Was Jeffrey Allen Dean arrested? When was Jeffrey Allen Dean arrested? What was Jeffrey Allen Dean arrested for?
Jeffrey Allen Dean was booked in Casey County, KY.
The following Official Record of Jeffrey Allen Dean is being redistributed by Mugshots.com and is protected by constitutional, publishing, and other legal rights. This Official Record was collected from a Law Enforcement agency on 11/07/2011.
Mugshots.com ID: 4507897
Name: DEAN, JEFFREY A
Age: 53
Race: White
Gender: Male
Eye Color: Brown
Hair Color: Brown
Height: 5′ 8″ (1.73 m)
Weight: 150 lb (68 kg)
Current Facility: Northpoint Training Center
Min Date: 11/26/2022
InmateID: 166488
Sentence Start Date: 5/17/2003
Names / Aliases: N/A
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Definitions for subbeadle
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an under beadle
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Cheer on your New York Giants in this More Than Enough tee from Majestic! It features printed New York Giants graphics and comes in team colors. You can support your New York Giants on and off the field with this tee. Show your favorite NFL team that you're a fan for life. Shop for your favorite NFL gear at Fanatics.com
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The once and future Paris transport museum
The huge Maison de la RATP on the quai de la Rapée has a sweeping view of the Seine and an impressive central atrium in which are positioned a few examples of historic trams and omnibuses. What it does not … Continue reading
Posted in Paris metro, Paris museums Tagged AMTUIR, Association pour le Musée des Transports Urbains, Chelles, Clive Lamming, Colombes, et Ruraux, Francois Siegel, Gare de Lyon, Harry Beck, Hector Guimard, Interurbains, Lapin de la RATP, Lapin du Metro, Les archives inédites de la RATP, les Halles, London Transport Museum, Maison de la RATP, Malakoff, Metro Insolite, Musée national des transports urbains, Paris metro, poinçonneur, poinçonneuse, RATP, Saint-Mandé, Univers de Leo 11 Comments
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SAMAR T-SHIRT DESIGN by IamAxiomWatch
©2009-2016 IamAxiom
A friend of mine asked me if I could design a tattoo for him. That was a little bit too much pressure so I told him "no but I can design a t-shirt print". He´s half pinoy- and very proud of it and a big part of his family is living on an island called samar- so that´s what I came up with...
nice design sir..i'm also from samar..can we use ur design for our shirt? if it's ok with you.
Hi, thanks for your request. Would you please give me your email adress so we can talk about this matter. You can find my email on my front page under my introductional text. Thank you
Haha, thanks. That´s what my Friend said as well- Pinoy-Power! I get a lot of good feedback to this piece. So it´s tempting to do that but as long as I don´t have a job where my task is to do so I don´t think I will do sth like this in near future again. Mainly because of the time I have, or actually the time I don´t have for sth like that But anyway, thanks for your feedback.
how long does it normally take u to make a print like this???
Sorry for my late reply. This piece took me about a month, but I didn´t work on it all the time, it was more that when I came from my job I worked on it from time to time. So it´s hard to guess. But I would say around 40 hours is realistic, maybe a little longer even...
so great and fine details!!!
Wow, I guess he's happy !
Yeah, indeed he still is. And for a year now he´s trying to make a poster out of it to hang it in his "man´s room". I´m curious if he´ll make it in 2011, but at least this piece generated some jobs for me in one or the other way haha
Wow ! Great vector !
Is this Illustrator work?


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Today's Belize Photo of the Day is the White-Collared Manakin and is scientifically known as Manacus candei. These compact forest birds are short-tailed, big-headed, but are quite tiny measuring to a mere 11 cm in length, and 18.5 grams in weight.
Today's Belize Photo of the Day is the Piper Auritum which is commonly known as False kava or Hoja Santa. The Piper Auritum is native to Central and South America and the West Indies and can be found on forest edges. The above picture was shot at Chaa Creek's private 365 acre nature reserve.
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AZ's new Cambridge HQ really is a work of art
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text:
From may point of view the comp driver would be just a configuration structure containing the content of the COMP_CSR register, the comparators output go to timers inputs that can be captured by the ICU driver or to EXTI inputs that can be handler by the EXT driver. Basically the support is mostly already there.
colin wrote:Hi Giovanni,
That's good to hear. Although I'm confused and saddened why the STM32F0 chips are hardly cheaper than the STM32F100 series.
E.g., Mouser prices:
STM32F051K8U6 US$3.17 (64K/8K, cheapest F0 on Mouser).
STM32F100C6T6B US$2.55 (32K/4K, cheapest F1 on Mouser).
STM32F100C6T6B US$3.76 (64K/8K, comparable to the F0 above).
I was hoping for a device to compete with LPC1000 series like
I may confirm your opinion - GDB server is in full, PRO version, without any restrictions.How about size limitations in this new Atollic GDB?
deserved to rejection, as it's not valid anymore...Note that less expert users could just use TrueSTUDIO as-is
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