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Final Four defeat was draining for UConn
|Connecticut guard Kelly Faris (34) passes between Notre Dame forward Natalie Achonwa (11) and Notre Dame forward Devereaux Peters (14) during overtime in the NCAA women's Final Four semifinal college basketball game, in Denver, Sunday, April 1, 2012. Notre Dame won 83-75. (AP Photo/Julie Jacobson)
DENVER — Kelly Faris' normally bright, expressive green eyes were red and swollen. An angry pout replaced her usual smile. She gritted her teeth as she attempted to talk about the good in the Huskies' season just moments after seeing it end in an 83-75 overtime loss to Notre Dame in the national semifinals.
"Right now, it doesn't seem like a whole lot," Faris said. "Looking back at the season. ... I don't think that's going to be in our heads for a while. It's not really our concern right now. (The loss) is going to be what we're thinking about. It will be a little rough. It's never fun going home with a loss. The thought doesn't leave quickly at all, or ever really."
Coach Geno Auriemma looked completely drained, as if all the effort he had poured into improving this team and overcoming considerable challenges to finish 33-5 and advance to the Final Four had caught up with him.
"All that seems kind of just OK at this point," Auriemma said. "It is always really hard to get to the Final Four, even the years it looks easy. So for this group, with a lot of the warts that we had to try to cover up all year long, for us to get here was a huge accomplishment. It would have been great if we had gotten one more rebound. To be playing (in the final) would be unbelievable for this group. But maybe we aren't there yet."
It's commendable where the Huskies did get, given the task they faced. They had to make up for the loss of Maya Moore with predominantly sophomore and freshman core players. They had to integrate Caroline Doty back into the lineup coming off her third ACL surgery. They spent the season searching for their next All-American and go-to player as well as a bench.
"It was a lot for us," freshman Kaleena Mosqueda-Lewis said. "We're a young team, but we're trying not to use that as an excuse. People say we don't have an All-American, but that wasn't an excuse for us. We've made it this far. I feel like that's just a credit to all the work we've done, a credit to the type of people that we have on this team."
Auriemma said this wasn't like other 30-win seasons where the Huskies played like a machine that steamrolled the competition. This was work, and in the end there wasn't much margin for error.
"This one was a struggle," Auriemma said. "And when you don't have the ability to have a guy on your team that can get 30 on any given night, and you know you need four players to get 15 maybe and you have to get every loose ball and you have to make sure you get every rebound and you've got to make shots and you've got to make every free throw, the intensity level is going to go up."
The coaching staff pushed the players to get the most out of themselves. Most responded at one point or another, particularly in the postseason.
"They've been through a lot," assistant coach Shea Ralph said. "Not just what we put them through, but what everybody's put them through. Everyone thinks that they stink, pretty much. And they've been compared every which way to every great player, and our older guys have endured, 'Connecticut doesn't have anybody to lean on, any senior leadership, any go-to player.'"
Ralph said she was impressed with the resiliency players showed. Bria Hartley emerged as a go-to All-American. Mosqueda-Lewis became a strong all-around player, rather than just a scorer. Stefanie Dolson fought through a sophomore slump to play incredibly well in the postseason. Faris stepped into a leadership role through her relentless style of play. Senior Tiffany Hayes stepped up in the Elite Eight game to get the Huskies to the Final Four.
The team suffered the most losses since the 2005-06 season, but it grew in the process.
"We always had faith,'' Doty said. "You get knocked down, you get right back up. It doesn't matter how many times. That's just our mentality. If you get punched a few times, you fix whatever you need to fix and you get right back out there. We're just so committed to the team. We're so committed to get a national championship, and we know we're going to keep fighting."
The Huskies struggled to find the necessary confidence and mental toughness over the final third of the regular season, but they persevered during the postseason to win their 18th Big East Tournament championship and advance to their 13th Final Four.
"When you look at what we have done this season, you have to be proud," Hartley said. "We fought through a lot this season. We had our ups and downs. To even get to a Final Four when no one thought we were as good or as dominant as previous UConn teams. ... We made it here. And we made it here just as far as we did last year. We are going to come back even stronger and use this as motivation for next year."
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More Uconn stories
- UConn women's notebook: Elite 8 toughest
- Geno hands out high praise as Huskies prepare for Wildcats
- UConn football: Huskies to open season with UMass at home
- Fullback a familiar spot for Seymour's Osiecki
- Senior guard Hayes finally receives recognition she deserves
- Huskies reach Final Four for 5th straight year
- How UConn turned its season around
- Huskies try their best to impress NFL scouts
- UConn women's notebook: Final 4 teams stood up to pressure
- Cleaveland: Huskies could be surprise of the Final Four
- UConn explores joining Hockey East
- UConn rookie unfazed by pressure of replacing Maya
- Lewis: Upgrade of UConn hockey should be put on ice
- UConn's Hartley on All-America team
- UConn notebook: Having best player not a must to win Final Four
- Familiar opponent awaits Huskies
- UConn women's notebook: Notre Dame's poise decisive
- Cleaveland: Huskies will learn from disappointing loss
- Final Four defeat was draining for UConn
- Huskies' duo: One injury-prone, the other durable
- NCAA denies UConn appeal to play in 2013 tourney
- 5 questions for the UConn women's basketball team
- Lamb departs for NBA; Drummond may follow
- Fanfare subsides as Cochran starts competing for job at UConn
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- Daigneault: For program's good, Calhoun needs to decide soon
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- Source: UConn's Drummond is one-and-done
- Daigneault: Andre, while not a UConn giant, was no bust
- Huskies lose Bradley; Oriakhi picks Missouri


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Author Archives: Villa Mansa Wine Hotel
(Español) Día de los Enamorados: Cena o Alojamiento+Cena
2 Febposted by Villa Mansa Wine Hotel
Categories: Hotel, Restaurant
Tags: 14 de febrero, Día de los Enamorados, San Valentin
Comments: 0
Menú Día de la Madre en Villa Mansa
14 Octposted by Villa Mansa Wine Hotel
Categories: Restaurant
Comments: 0
Para festejar este día de la madre te esperamos con un delicioso menú para disfrutar en familia y agasajar a mamá. Te esperamos este domingo 18 de Octubre desde las 12hs en Villa Mansa y hasta las 15hs.
¡Las mamás que vengan se llevarán un 15% de descuento en Tardes de Té para volver a disfrutar con sus amigas!
(Español) Dia del Maestro con una deliciosa Tarde de Té
9 Sepposted by Villa Mansa Wine Hotel
Categories: Restaurant
Tags: Día del Maestro, Tarde de Té
Comments: 0
(Español) Día del Amigo con un Tapeo para Compartir o Tarde de Té
15 Julposted by Villa Mansa Wine Hotel
Categories: Restaurant
Tags: Dia del Amigo
Comments: 0
What guests are saying ...[About a Boutique Hotel in Mendoza]
12 Mayposted by Villa Mansa Wine Hotel
Categories: Hotel
Tags: tripadvisor
Comments: 0
After 4 years since our opening, it have been several guests who have chosen the tranquility of Villa Mansa and have captured their experience on TripAdvisor. Today we share some comments from our guests who have filled us with pride and can also help you to organize your days in Mendoza.
"More than excellent"
Andy from Tucumán in September 2014 wrote:
A perfect place! Supersized rooms, super modern, clean and very well staged common areas.
Ideal for a snack of cheese and wine next to the pool watching cordillera.-
Barbara is the friendliest receptionist I met, very nice on the deal, diligent and always ready to answer all our questions.-
You must try the duck sorrentinos, pumpkin soup, salad, oh well Everything!
I recommend it 100%
"Excellent staff, excellent restaurant"
Mariela from Buenos Aires shared in June 2014:
While the hotel and grounds are immaculate and beautiful view, especially regarding the attention provided by all staff, which is super personalized and friendly. Meanwhile the restaurant is high level and the short menu is impeccable. We spent a great day
"Perfect short stay"
Aimee from Australia in August 2014 wrote:
Stayed for 1 night and wished it was longer. It was a lovely Bodega outside of the city which I recommend if your keen on spending most of the time at wineries. The staff at reception were fantastic in helping us plan our two days with Marcelo the driver- while not cheap, we were glad we didn't hire bikes on reflection as wineries looked a little hard to find. Rooms & bathrooms were modern and spacious. Great bed too! Breakfast was enjoyable and option of eggs too was a nice surprise. Recommend Ruca Malen for lunch which they recommended, Archaval Ferrer winery which was by far the best wine tasting we had
"Quiet place to rest"
Lorena in October 2014 from Brazil wrote us:
The location is ideal for relaxation, away from the center of Mendoza. Hotel very good and affordable restaurant.Wonderful service !!Comfortable bed, living room, room service. Ideal for couples and newlyweds l of honey.I recommend!
We thank all our guests for taking the time to share your comments and give us beautiful comments of Villa Mansa that help us to know that we are on track and give us the opportunity to improve every day a little more.
We invite all our guests to share their experience and recommendations as they help all travelers to organize their holidays in Mendoza.
photo credit: Got Feedback? via photopin (license)
5 particularities of Mendoza that you did not know
8 Marposted by Villa Mansa Wine Hotel
Categories: Sin categoría
Tags: acequias, costumbres mendocinas, siesta, viento zonda
Comments: 0
We all have things that make us unique and Mendoza no slouch. If you are about to visit Mendoza we anticipate you some peculiarities of our province that surely did not know and when you will arrive it could draw your attention
All activities and events Harvest 2015 in one place
22 Febposted by Villa Mansa Wine Hotel
Categories: Actividades
Tags: Fiesta de la Cosecha, fiesta nacional de la vendimia, Megadegustación
Comments: 0
The National Harvest Festival is linked to the culture and history of the people of Mendoza, but it is not only the Central Festival the only one to visit, weeks before the festival the province offers several events to enjoy this unique atmosphere that characterizes Mendoza .
Here are some events that we recommend to live Mendoza Harvest:
(Español) Menú de los Enamorados
5 Febposted by Villa Mansa Wine Hotel
Categories: Restaurant
Tags: Día de los Enamorados
Comments: 0
(Español) 5 Estilos Arquitectónicos para Disfrutar en Bodegas de Mendoza
28 Janposted by Villa Mansa Wine Hotel
Categories: Actividades
Tags: Belasco de Baquedano, Bodega Séptima, O Fournier, Salentein, Trapiche
Comments: 0
New Year Eve Menu
22 Decposted by Villa Mansa Wine Hotel
Categories: Restaurant
Comments: 0
photo credit: Christian Kaden via photopin cc

subset: commoncrawl


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Daddy Williams' Toy Shop is the center of interest to "Toad" and his friends long before Christmas arrives. They plan a surprise that brings joy to a poor family. The boys erect snow forts and the two sides have a battle royal.
remark as he entered the room.
"We're going for Christmas greens and Dad's going to cut our tree from away up on the hillside," Toad told him, "and," he added, "we're going to take one of the horses with us to drag it home."
"Oh, that's great!" replied Reddy. "Do you start soon?"
"Don't you want to go, too?" asked Chuck. "And maybe we can get Fat and Herbie, too," he added.
"If such a crowd goes, and everybody gathers greens," laughed Toad, "what will we ever do with all of them?"
Mother Brown answered him from the doorway.
"Why not take some of them to the church? I'm sure the ladies who are trimming it will be glad to use all that you can give them."
"That's a splendid idea," declared Father Brown, rising from his seat by the fireplace. "Come, boys, bundle up well, because it's going to be a cold drive."
"I'll run ahead to get the others," called Chuck as he hurried from the room.
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Shop Sections
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Fort Worth, TX, United States
Have a question?Contact the shop owner.
Need a custom order?Request Custom Order
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Opened on Jan 26, 2012
- About
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Handmade Eclectic Home Items
Welcome to my shop where I make beautiful, fun, useful items for the home. I love fabric and finding new uses for old and odd pieces. As I make items, the collection will be more eclectic. I keep adding to my stash, and it's all just waiting to be put to use and I hope you find something that speaks to you!… read more
This shop accepts Etsy Gift Cards.


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No finger loops here! This series was designed for angling in cold weather where gloves or mittens are the norm, or for tangling with big fish. If you've ever had your knuckles mashed by a powerful fish, the beauty of these clamps becomes apparent. Excellent for salmon and steelheaders. Simply squeeze the clamp all the way through the ratchets to release. To close, squeeze until the ratchets lock. This one-hand wonder is spring-loaded, has a wrist lanyard, and can easily handle all streamside tasks.
Clamps are designed for a myriad of tasks like crushing barbs, removing hooks from fish (or yourself!), opening/closing split shot, knot-tying, cutting tippet, etc. Knowing what tasks you regularly perform stream-side will help you select the clamp(s) that best suit your angling needs. Clamps tend to be a very personal item, and like a favorite rod or reel, people have preferences for their clamps. Some anglers like short clamps and others prefer long. Some like straight jaws while others prefer curved. Many like the gold loops/handles and others prefer the stealth-mode black. So, if you lose your buddy's 5†curved black clamp, don't assume the 4†gold loop straight model you gave him off your vest will clear the air.
Features :
Finish : check for availability
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These people who use "really" to describe things that aren't actually real! They're the worst, aren't they? As we all know, "really" is the adverbial form of the adjective "real", and "real" means "ac... Read More
Oh no! What are we to do? People are using "literally" to mean "not literally"! The world is metaphorically coming to an end! I don't want to single out Buzzfeed, but it was their article that caught ... Read More
Oh, I know, I know. "David Silva literally floats around the pitch"; "In his youth, Michael Owen was literally a greyhound." "That's not what 'literally' means, you dolt," the snobbish middle-class fo... Read More


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Photos: Black Eyed Peas @ Verizon Center
I'll never be able to forgive the Black Eyed Peas for inflicting "My Humps" on the world, but they sure put on a pretty fun show. More photo evidence after the jump and at the full gallery.
Ludacris was second on the bill but seemingly nearly as much a draw as the headliners:
The horrendously bad LMFAO opened the show:


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Tiziano Ferro (born 21 February 1980) is an Italian singer-songwriter, producer and author. He broke through in 2001 with his international hit single "Perdono" and has remained commercially successful since then, primarily in his home country. Ferro has released a Spanish version of each of his albums, and has also sung in English, Portuguese, and French. Known as the modern face of Italian pop music, he frequently writes songs for other artists and has produced albums for Giusy Ferreri, Alessandra Amoroso and Baby K.
List of links to Tiziano Ferro fansites:


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Taliban, Islamic State clash in eastern Afghanistan
The Taliban and al Qaeda have a vested interest in halting the spread of the Islamic State in Paktika, given the province's importance to the two jihadist groups. Read more →
The Taliban and al Qaeda have a vested interest in halting the spread of the Islamic State in Paktika, given the province's importance to the two jihadist groups. Read more →
Libya's air force confirmed that a jet was shot down by anti-aircraft fire earlier today. Ansar al Sharia Libya, which says its fighters were responsible, openly promotes al Qaeda ideologues in its propaganda. Read more →
The photo offers more evidence of another Iranian-backed militia in Iraq owning and using a US-made M1 Abrams tank. Read more →
Jalal Bala'idi, a prominent AQAP field commander khow is also known as Hamza al Zinjibari, "was killed in a Crusader strike that targeted him while he was amongst the sons of his tribe in Abyan province," the jihadist organization confirmed. Read more →
Attacks like this continue to show that the security situation inside Mali, especially in the north and increasingly in the south, is still volatile despite a French-led counterterrorism mission and an UN peacekeeping force inside the country. Read more →
"The Islamic Emirate [of Afghanistan] has not readily embraced this death and destruction for the sake of some silly ministerial posts or a share of the power," the Taliban stated. Read more →
The jihadist group has long targeted hotels in Mogadishu, as they are popular with governmental and African Union officials and foreigners. Read more →
Despite contradictory claims made by Kenya, the photo report appears to confirm a large number of Kenyan troops were killed in the attack. Read more →
The Al Qaeda group continues to take Western hostages throughout the Sahara and the Sahel. Read more →
The Al Qaeda groups continue to strike at popular hotels throughout West Africa. Read more →
The US has treated the Islamic State Khorasan Province as a terrorist organization long before officially listing it. Four senior Khorasan Province leaders have been killed in US airstrikes over the past year. Read more →
A Guantanamo detainee who was transferred to Kuwait in 2006 had quickly returned to the battlefield. He killed 13 Iraqi soldiers in a suicide truck bomb at a combat outpost in Mosul, Iraq in 2008. Read more →
The Islamic State's Libyan "province" has released images from the captured town of Bin Jawad. The jihadists have likely operated in the town for months, but they only declared complete control of it earlier this week after launching a new offensive. The photos and a short video released by an Islamic State-affiliated "news" agency are intended to advertise the jihadists' control of Bin Jawad. Read more →
The Kurdish YPG (or People's Defense Units) has released a summary of its operations for 2015. The YPG claims to have killed nearly 6,000 "enemy" fighters, most of whom likely belonged to the Islamic State, while losing just 680 of its own members in combat. The statistics provided by the YPG imply a kill ratio of nearly 9 to 1, which obviously seems high. Read more →
The Islamic State's Libyan "province" has released photos documenting yesterday's assault on an oil facility in the port town of Al Sidr. Read more →
If confirmed, the Turkistan Islamic Party is not the only jihadist group to have used the US-made anti-tank missiles. The Islamic State, Al Nusrah Front, and the Caucasus Emirate in Syria have all released propaganda showing its forces using the TOW missiles. Read more →
"Six Resolute Support service members died as a result of a vehicle-borne improvised explosive device attack in Bagram, Afghanistan," the international coalition confirmed. Bagram is a high priority target for the Taliban. Read more →
Afghan security forces claimed it ejected the Taliban from the Khanashin district center in southern Helmand province, while the Taliban claimed it seized control of Marawara in Kunar. Read more →
The failure to mention al Qaeda's renewed oath to the Taliban in the military's latest report on Afghanistan is no accidental omission. Read more →
The role of terrorist-backed media has emerged as an area of concern not only in the West but across the Middle East as an increasing number of individuals are incited to violence by these outlets. Saudi Arabia is the latest country to shut down Al-Manar. Read more →
The State Department has designated Emrah Erdogan as a terrorist, describing him as a member of both al Qaeda and Shabaab, al Qaeda's official branch in East Africa. Read more →
Abu Muhammad al Julani will appear at a press conference "soon," according to Al Nusrah Front, al Qaeda's official branch in Syria. The timing of his appearance was likely influenced by the Syrian opposition's meeting in Saudi Arabia this week. Al Nusrah is not represented at the gathering. Read more →
Khanashin district in Helmand province was a Taliban haven long before the district center fell earlier today. The Taliban now controls 37 districts in Afghanistan and contests another 39. Read more →
The photo shows two young jihadists before undertaking the attack that left more than 20 people dead in Mali's capital late last month. Read more →
The Islamic State's Al Bayan "news" bulletin describes the San Bernardino terrorists as "soldiers" of the "caliphate" in English, but as "supporters" in Arabic. The group has not claimed that the shooters received any operational direction or assistance. Federal authorities are still investigating that possibility. Read more →
The 'Amaq News Agency, which is affiliated with the Islamic State, issued a statement saying the San Bernardino shootings were the work of the jihadist group's "supporters." However, the message is not an official claim of responsibility and didn't include any details that were not already available in the Western press. Read more →
Shabaab, al Qaeda's official branch in Somalia and East Africa, continues to be a capable insurgent and terrorist group in the region. Read more →
After overrunning the Abu Duhour airbase in Idlib province in September, Al Nusrah Front executed dozens of Syrian soldiers. A new video posted online by Al Nusrah highlights the dramatic tension just beforehand. Read more →
Iranian-backed Shia militias are fighting for Assad in Aleppo as regime forces, backed by Hezbollah and Russian airstrikes, try to push back jihadists and rebels in the northern province. Read more →
While western officials still seek to negotiate with the Afghan Taliban, the group continues to support attacks in Western countries. The Taliban said France's "colonial policy" justified the murders in Paris. Read more →
Harakat al Nujaba leader Akram al Kaabi met with Qassem Soleimani, the commander of Iran's Qods Force, in Aleppo, Syria, according to the Iraqi Shiite militia. Read more →
The photos mark one of the first times a Humvee has been captured by a jihadist group in Syria, and indicate that Iraqi militias have transported US-made military hardware from Iraq to Syria. Read more →
The strikes that targeted "Jihadi John" and Abu Nabil should serve as a reminder that 14 years after the September 11, 2001 attacks on the US, the military and intelligence establishment remain hyper focused on targeting individuals in the hopes of causing the collapse of jihadist groups. Read more →
Al Nusrah Front has accused the Shuhadaa Al Baydhaa brigade in the northern part of Homs province of secretly serving Abu Bakr al Baghdadi's Islamic State. The brigade denies this allegation. Al Nusrah raided villages under Shuhadaa Al Baydhaa's control and claims to have captured "spoils." The move may be intended to secure a supply route for Al Nusrah into Homs. Read more →
The Uighur group continues to fight alongside Al Nusrah Front, an official branch of al Qaeda, in northwestern Syria. Read more →
The Islamic State's Aleppo "province" has released a video congratulating its brothers in the Sinai "province" for downing a Russian airliner on October 31. The video is at least the fourth time that the Islamic State has claimed responsibility for the crash. The group has not provided evidence proving its culpability thus far, but Western officials say it is increasingly likely. Read more →
The predominately Chechen group also says it fighters recaptured a hill from Russian forces in the Latakia province in recent days. Read more →
Photos released by the jihadist group show its "Third Armored Brigade" using US-made MRAPs to train in northern Iraq. Read more →
Jaysh al Islam is reportedly using captured civilians and fighters as human shields to deter airstrikes in the Al Ghouta region of Damascus. Read more →
In an interview with the Washington Post, General John Campbell described an al Qaeda camp in southern Afghanistan as "probably the largest training camp-type facility that we have seen in 14 years of war." The camp is one of two raided by joint US-Afghan forces in Kandahar earlier this month. Read more →
While most Shabaab attacks are located in the capital of Mogadishu or in the south, the jihadist group maintains the ability to launch operations in the country's central regions. Read more →
"Hizb-i-Islami neither has relations with the Islamic State, or any commitment to the group, nor has it announced any support of that group," Gulbuddin Hekmatyar said in mid-October. Read more →
Three jihadist groups have formed Jund al Malahim ("Soldiers of the Epics"), a joint operations room opposed to the Assad regime and Russian forces in the Ghouta region of Damascus. Read more →
The military's claim that the US troops who participated in the operation were military advisers and not engaged in a combat mission is implausible, given the involvement of Delta Force operators. One US soldier was killed. Read more →
Officials continue to whitewash the role that Iranian-backed Shiite militias play in Iraq's offensive against the Islamic State. The US continues to provide airstrikes to these militias, which are Iranian clients responsible for killing hundreds of American soldiers and remain hostile to the US. Read more →
The Afghan Taliban claimed it overran the district center of Ghoryan in the western province of Herat. Afghan forces later retook the district. Thirteen districts have fallen to the jihadist group in the past several weeks. Read more →
The jihadist group continues to fight for control of the northwestern Afghan province of Faryab, where two other districts fell to the Taliban over the past 10 days. Read more →
The photo comes just days after Soleimani was spotted in Latakia addressing Iranian and Syrian troops. The Syrian regime also relies on Shiite militias from Iraq and elsewhere, which are often trained and advised by the Iranian Qods Force. Read more →
Online jihadists are claiming that an al Qaeda leader known as Sanafi al Nasr has been killed in an airstrike in Syria. Nasr's death is not confirmed and he has been reported dead before. The latest claims come from al Qaeda members who apparently knew Nasr and interacted with him online. Read more →
A New York Times map, based on data provided by The Long War Journal, shows the deteriorating situation in Afghanistan. President Obama's decision to keep 5,500 troop in country past 2017 will not be enough to turn the tide. Read more →


text: Share It MainStoriesSpecial Olympics Dusseldorf 2014 Special Olympics Dusseldorf 2014 Sonja Schmeißer | Feb 06, 2014 | Europe Eurasia: Germany This spring, 4,800 athletes will participate at the next National Summer Games from Special Olympics Germany in Dusseldorf from May, 19th to May 23rd, 2014, according to the motto "Gemeinsam stark – Together strong". With coaches, caregivers, family members, more than 2,000 volunteers and daily participants more than 14,000 people will be involved in the National Games. The athletes will start in 18 sports disciplines: badminton, basketball, bocce, bowling, beach volleyball, football (soccer), golf, handball, judo, kayaking, powerlifting, athletics, cycling, equestrian/vaulting, roller skating, swimming, tennis and table tennis. Additionally 254 people without disabilities will follow the motto "Gemeinsam stark" and will participate in 13 Unified sports disciplines. As the 19th sports discipline the Motor Activity Training Program (MATP) is open to all visitors. You can find a schedule and further information about the Special Olympics Dusseldorf 2014 on our website (in German). Related:Get more details Read More Stories More Than an Athlete Katie BaumBrian Bates of Iowa is not only a dedicated athlete, but also a volunteer when he is not competing.Top Snowboarders Defend Gold at Unified Race at X Games in AspenChristy WeirSpecial Olympics Athletes "Redefined Winning" On the Way to Social ChangeChristy Weir"I'm a winner!" One mom's thanks to Special OlympicsAmie DuganAt the team tournament in December, Nick looked at me and said, "I'm a winner!" That is a most treasured moment and memory for me!A Figure Skater's Life TransformedSuzanne Coogan'When I'm on the ice I feel as free as a butterfly' - Stephanie Gott.Suzanne CooganInternational Competition Inspires Athletes from PolandSuzanne CooganGreat Britain's ITV News Report Captures Spirit of AthletesMaureen RabbittSpecial Olympics Los Angeles 2015Alex YangEunice Kennedy Shriver's Impact is Still FeltJason SchrimlWearing a real uniform makes Special Olympics athlete and his family happy and proudSerkan OvatmanDo You Have A Story to Share?Share Your Story


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Oral and Maxillofacial Pathology Biopsy Service
(Oral Pathology Group)Â
Click here for information about ordering biopsy kits.
Click here to view a sample report.
For additional information or questions on any of the above, please call Jenny Robison at (317) 274-7668.
Questions about insurance or billing? Contact Lasheka Person at (317) 274-5140.
News and Updates
Dear Doctors,
My name is Jenny Robison and I am here to help you with your PECOS registration. I am asking that you complete your registration ASAP, so that we may accept specimens from your Medicare patients! Once you receive confirmation, please fax the documentation to (317) 274-3346, e-mail me at firstname.lastname@example.com or call me at (317) 274-7668. Simple instructions on signing up are below.Â
We mailed a letter to your office in late 2010 explaining that in order to submit biopsies to any lab on Medicare patients, Medicare is requiring that you register with PECOS as a non-Medicare provider (the original deadline for this requirement was July 1, 2011, but Medicare has stated that the due date has been moved further out; a new due date has not been announced). Â
Medicare has recently changed the registration process for PECOS only providers to a simplified internet-based submission. Please see below for instructions and information.
Advantages of Internet-based PECOS
• Faster than paper-based enrollment (45 day processing time in most cases, vs. 60 days for paper)
• Tailored application process means you only supply information relevant to YOUR application
• Gives you more control over your enrollment information, including reassignments
• Easy to check and update your information for accuracy
• Less staff time and administrative costs to complete and submit enrollment to Medicare
Note: Providers and suppliers must have Internet Explorer version 5.5 or higher and have the most recent version of Adobe Acrobat Reader before initiating an enrollment action using Internet-based PECOS.
You will access internet-based PECOS by using the userID and password that your office established when the office applied on-line for a National Provider Identifier (NPI). You would have done this through the National Plan and Provider Enumeration System (NPPES).  If you didn't establish a userID and password at that time, for example, you may have submitted a paper NPI application and had no reason to establish an online sign-on, or your office has forgotten your User ID or password,  you may reference these FAQs for instructions.Â
Below are instructions for PECOS registration:
- Click https://www.cms.gov/MedicareProviderSupEnroll/04_InternetbasedPECOS.asp.Â
- Click "Internet-based PECOS" link on the left side of the screen
- Scroll down and click on "Access to Internet-based PECOS" under "Related Links" at the bottom of the page.
- On the next page, "Medicare Enrollment for Providers and Suppliers," click "CONTINUE" at the bottom.Â
- The next page is "Welcome to the Medicare Provider Enrollment, Chain and Ownership System (PECOS)" Â
on this page, SCROLL DOWN to the bottom and log on with your NPPES User ID and password.Â
- The next screen is Medicare Enrollment for Providers and Suppliers, Home, "Welcome ." Click "my enrollments" and then "new application."Â
- Complete and submit the electronic enrollment application. The system will walk you through the application process and supply you with a 2-page Certification Statement.Â
- You will need to mail the original signed Certification Statement and supporting documents to the Medicare contractor (which will be automatically pre-printed on your form for you) within 7 days of your electronic submission. The effective date of filing an enrollment application is the date the Medicare contractor receives the signed and dated (blue ink recommended) Certification Statement. Note: A Medicare contractor will not process an Internet enrollment application without the signed and dated Certification Statement.
Below are links you may need.
Enrollment example and step-by-step screen views
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Check status
Once your enrollment is approved, you should receive a letter from Medicare stating that you are registered for the sole purpose of ordering and referring items or services for Medicare patients to other practitioners. Once received, please fax us a copy of this letter to (317) 274-3346.
Please contact me if I can help in any way.
We appreciate your confidence in our practice, and we thank you for going through this process to serve our mutual Medicare patients better.
Thank you!
Jenny Robison


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|ETHICON ENDO-SURGERY Patent applications
|Patent application number
|CIRCULAR STAPLER INTRODUCER WITH RIGID DISTAL END PORTION - Introducers for introducing a surgical circular stapler into a patient. Various embodiments comprise a hollow flexible sheath that has a distal end and an open proximal end that is sized to receive a stapling head portion of the circular stapler therein. A rigid cap assembly is attached to the distal end of the hollow flexible sheath. The rigid cap assembly may be configured to selectively move between a closed position wherein a distal face of the stapling head is covered when inserted therein and an open position wherein the cap assembly may be withdrawn from around the stapling head and elongated shaft. A release arrangement interfaces with the rigid cap assembly such that upon an application of a release motion thereto, the rigid cap is movable from the closed position to the open position.
|INSERTION DEVICE WITH FLOATING HOUSING AND METHOD OF USE - An insertion device configured for providing access to a treatment site within a body cavity is provided herein. In general, the device includes an elongate cannula configured to receive and allow passage therethrough of a surgical instrument to a treatment site. Additionally, a proximal end of the cannula is movably coupled to a housing thereby facilitating delivery of the instrument therethrough. Additionally, various embodiment of a method for delivering (e.g., laprascopically, endoscopically, etc.) various surgical instrument to various treatment sites via an elongate cannula wherein the cannula includes a proximal end movably coupled to a housing are provided herein.


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November 11, 2013, President George W. Bush surprised a few groups of veterans, including members of the Southern Methodist University's student veterans groups and the Sons of the Flag, during their Veterans Day visit to the George W. Bush Presidential Center. Also pictured is Col. Miguel Howe, USA, Ret.; Director of the George W. Bush Institute's Military Service Initiative. Veterans Day visitors to the Bush Presidential Museum are greeted by President Bush in this video message.
Among those in attendance were Colonel Charles "Chuck" DeBellevue, USAF (Ret), and his wife Sally. While serving in the U.S. Air Force during the Vietnam War, Col. DeBellevue became the first Air Force Weapon System Officer to become a "Flying Ace." He received the Air Force Cross, the second highest military award that can be given to a member of the United States Air Force.
Thank you for your service Colonel DeBellevue and to all the men and women who have served in the United States Armed Forces.
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Tag Archives: art in Utrecht
Dog Days of Summer
This week I thought I'd share some of the random photos I've taken around town. Some are funny, some are interesting window displays, and others are quiet, pretty corners easily missed.
First up is the charming statue of Biru the chow chow, a sculpture by artist Joop Hekman. I had seen the other two dogs coming and had hoped that they would stop and give Biru a friendly sniff, but they were too distracted to pay attention to a dog of bronze rather than flesh and fur. I didn't get the shot I wanted, but I was happy to get the shot I did.
Utrecht As Art
The art scene in Utrecht is thriving and active, with numerous groups and individual artists doing their thing, be it traditional canvas painting or guerrilla knitting.
The CBKU, a non-profit art organization located on the Plompetorenacht, is active in promoting art of all types by up-and-coming artists in Utrecht. They've got Facebook pages, Twitter feeds, and they've got an online magazine, called Lucy. I came across Lucy today while following a link to an article about a recent gathering of artists who went out and made the city a little bit more artistic one recent Saturday night.
While looking through the e-zine, I came across what will be a recurring series: Zicht op Utrecht (View of Utrecht) by Nina Mathijsen. Every two weeks, the magazine will be posting aquarelle images of Utrecht, particularly its urban transitory construction architecture, as seen by illustrator and typographer Nina Mathijsen. The first of the series is posted above. I'm looking forward to following her interpretation of the city as it changes. What is shown in this first image is the area around Vredenburg, where the music hall is being rebuilt, and where one of the ring canals is returning. That whole part of town is a mass of construction, with the train station and the Hoog Catharijne shopping center soon to be joining in on the revamping. Tower cranes abound, giving tall competition to the Domtoren.


text: 1.4k 12 Comments Sep 27th Secret Ships' wonderful home goods and fashions from all over the planet! Our newest, awesome sponsor Secret Ships is a recently-launched online boutique that carries a global selection of affordable home goods, clothing, and accessories. You can shop all over the world — Latin America, The Middle East, India, Asia, and Africa — in one convenient space. Read More 4.7k Aug 28th Tiny Casita: converting a $200 trailer into a sweet mobile casa Thanks to the Tiny House Blog for introducing me to Greg Fowkes' story. He's a new dad who's converting a $200 trailer into an amazing modern mobile home that he, his wife, and their new baby can drive down to Mexico and live in. As Greg says, "When you think about getting back to basics, what could be more basic than family? Change starts at home." Read More 3.0k 14 Comments Jul 19th Summer drink inspiration: Mexican horchata recipes Horchata is a cold Latin American and Spanish rice-based drink usually flavored with cinnamon and vanilla. Needless to say, it pairs really well with spicy Mexican food and is a great summer drink. But after seeing these Horchata-flavored cupcakes from Just Jenn Recipes, I went looking for more interesting ways to dress it up. Read More 2.5k 14 Comments Jan 20th Shop eccentric houses through AirBNB Husband and I have been happily hosting AirBNB guests for six months now, and it's an amazing place to find unusual housing types you might want to try out! Read More 95 Nov 1st Sugar skulls of Toluca: sparkling up in your face I'm loving this time of year. Here I was, thinking the city went crazy for El Dieciséis, but Day of the Dead is so much more colorful, and soulful. Brightly colored sheets of papel picado hang in store windows. Velvety, crimson terciopelo flowers sit in vases at restaurants. Orange marigolds, the traditional Day of the Dead flower (called cempasúchil in Spanish) have suddenly bloomed in the street medians. Read More Copyright © 2003 - 2016 Offbeat Empire. All rights reserved. Unauthorized reproduction in part or in whole is prohibited. Illustrations by Ursula X. Young Contact us Terms of Service | Privacy Policy | Monetized by SkimLinks


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EchoStar Corporation
News about EchoStar Corporation, including commentary and archival articles published in The New York Times.
Playing It Close in Wireless, With an Eye for Satellite Deals
Charles Ergen, chairman of Dish Network and EchoStar, has been on a takeover spree this year, making more than $2 billion in acquisitions.
June 23, 2011, Thursday
Dish and EchoStar Settle Patent Dispute With TiVo
Dish and EchoStar will pay TiVo $500 million to settle a patent infringement suit involving TiVo's video recording technology.
May 3, 2011, Tuesday
Dish Network Wins Auction for Blockbuster
After a bankruptcy auction that extended into the early hours on Wednesday, Dish Network announced that it had emerged as the winner of Blockbuster's assets, with a bid valued at $320 million.
April 6, 2011, Wednesday
EchoStar in $1.3 Billion Deal for Hughes Communications
The deal "will create a powerful leader in video and data transport," Michael Dugan, EchoStar's chief executive, said.
February 14, 2011, Monday
Dish Network and EchoStar a Fit for AT&T, Report Says
Shares of Dish and EchoStar rise after Credit Suisse analysts suggest that AT&T could offer more than $20 billion for the companies.
February 10, 2011, Thursday
Dish Network Poised to Land DBSD for $1 Billion
After a drawn-out court battle, Dish Network is set to acquire the satellite operator DBSD North America for about $1 billion as it emerges from bankruptcy.
February 1, 2011, Tuesday
For Foundry, V.C. the Old-Fashioned Way
Like students who choose to go to college in a small town to avoid the distractions of big-city life, the venture capitalists at Foundry Group have shunned Silicon Valley or New York for Boulder, where they practice back-to-the-basics venture...
May 14, 2010, Friday
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Clip From
March 5, 2013 U.S. Rural Economy
House Ag On Rural Economy
Rep Marcia L. Fudge D-OH & USDA Secy Tom Vilsack
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- Rick Crawford U.S. Representative Candidate (Former) [D] Georgia
- Thomas "Tom" J. Vilsack Secretary Department of Agriculture
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text:
it's ironic,
isn't it? the way
they say "hunger gnaws"
like the way our teeth
scrape against bones.
for all the
calories that are counted,
you still feel
empty. you aren't
beautiful until
you are digesting
nothing but air
and maybe your own guilt.
that's just the way
living is these
days: swallowing
glass shards to
slice up your insides so
you can ignore
the other kind of pain your
stomach is feeling.
but when people ask
if you're doing okay you just
smile and nod even though
you can't help but
think "if honesty was
tangible, i'd eat it right
life has
an acquired taste and
some days you'd
like to rip your
tongue out.
sati(ate)d by lupus-astraWatch
©2013-2016 lupus-astra
a collection of messy thoughts
while staring at my dinner plate.
That last stanza.
Our society is so fucked up. It's literally not possible to look like the girls in the magazines, because most of them are Photoshopped beyond all recognition.
"if honesty was
tangible, i'd eat it right
tangible, i'd eat it right
Oh I feel this.
I love you. I love you. I love you.
Please remember that!
Please remember that!
this is real poetry. raw and gripping; and nonetheless with a subject that is so difficult to portray originally.
just, wow.
I like the way you've portrayed food in contrast to the notions of diet and physical portrayal that one has. Its a good food for thought literally and pun intended. What I appreciate about it is the second last stanza - I know that feeling, but wasn't able to put it in words.
You were spot on there. Well done. Really! This is a well done work. I like how you've captured the (ate) part in the word satiated - giving it a double meaning. Well done
absolutely adore this..
absolutely adore this..
Love it! The pessimism!
I have to start by saying that this poem is damn amazing.
I love reading poetry with great imagery and perfect metaphors.
This is inspiring to me, actually, because I've been on the other side of it. Some people starve themselves because they feel like that's what the world expects of them (or whatever their reasons may be) and some people are starving just because they're struggling through life.
Thank you, for this. I wasn't able to properly convey my feelings on the first half of my life, but now I feel inspired and more confident that I may do so.
Thank you very much. Your words mean a lot to me. <3 I'm glad I inspired you even though this is kind of a very depressing piece.
I tend to be kind of a very depressing person at times.
Well, it seems like I write more from experiencing sorrow than I am able to from joy. I suppose that's how it is for any artist?
"if honesty was
tangible, i'd eat it right
tangible, i'd eat it right
my goodness. :Heart:
Oh my god, this reminds me off my best friend.
I hate it when my poetry reminds people of things because normally they're painful and I don't want that
Poetry is one whay I can deal with memories. i don't mind reminders when they're well written. ^^
This is really beautiful. You have an amazing talent !
I hope you'll soon manage to love yourself without starving... I'm sending you all my support !
I like your intangible discussion on hunger here and your parallel to messiness and acquired taste. It's an interesting metaphor.
This was so well written, amazing ^^
Brilliant imagery.
OMG. I love this. Absolutely brilliant. Amazing. (Despite being rather depressing) You have such a talent for conveying the emotions really effectively. You get your point across so clearly. I love this.
This was really beautiful, and although I don't fill myself with air, sometimes I just feel like shoving it down my throat. I guess we all have those days, y'know?
This was really cool.
I like the whole theme made with words like "digest" and "eat" and all that. It's pretty cool
Emptiness often fills me, and I am very familiar with the taste of your cuisine. Slowly the richness drains from me for all those not unlike you.
it's not really fun, huh.
I admit though, you are very capable of making others feel it. Dark mirrors, black holes, bottomless pits and some souls share an unwanted affinity.
ahhh please stop with this depressing life you have. I want to see something positive about your life not something like this. why must you ruin yourself with these views whilst you eat your dinner ahhh i just want to go and hug you and tell you it's okay and basically give you cuddles all day long and make you feel happy again.
this is an old one though, I just needed to publish something...I'm feeling okay enough right now
sorry to worry you
I see....


text:
Are you H Hoehn?Claim your profile
Publications (175)795.71 Total impact
Article: Living related liver transplantation in an adult patient with hepatocellular adenoma and carcinoma 13 years after bone marrow transplantation for Fanconi anemia: A case report[Show abstract] [Hide abstract]
ABSTRACT: Fanconi anemia (FA) is an inherited bone marrow failure syndrome due to defective DNA inter-strand cross-link repair. Hematopoietic stem cell transplantation (HSCT) is curative for pancytopenia, but may not prevent the development of non-hematological malignancies. We describe a 26-year-old male patient with FA and Marfan syndrome who in 1994 underwent successful HSCT with bone marrow stem cells from his human leukocyte antigen (HLA)-identical sister. In 2006, three lesions in the liver were detected and resected. The three lesions all showed activation of the β-catenin pathway and were histologically characterized by a highly differentiated steatotic hepatocellular carcinoma (HCC) with remnants of the underlying adenoma from which it arose, a hepatocellular adenoma with foci of well-differentiated HCC, and a cholestatic adenoma. Risk factors for the emergence of HCC included FA itself, the use of androgens for a period of 3 years preceding HSCT and toxicity of the conditioning regimen. Because of the danger of developing additional HCC, liver transplantation was proposed, taking into consideration that immunosuppression would increase the risk of other malignancies. By using part of the liver of the sister, who already acted as bone marrow donor 13 years earlier, immunosuppression could be avoided. Liver transplantation was performed in 2007 without complication. Five years after liver transplantation the patient is doing well. This case is twofold special being the first case reporting FA co-occurring with Marfan syndrome and being the first reported case of FA treated for HCC by liver transplantation from a HLA-identical sibling donor without the use of immunosuppression.
Article: WRN mutations in Werner syndrome patients: Genomic rearrangements, unusual intronic mutations and ethnic-specific alterations[Show abstract] [Hide abstract]
ABSTRACT: Werner syndrome (WS) is an autosomal recessive segmental progeroid syndrome caused by null mutations at the WRN locus, which codes for a member of the RecQ family of DNA helicases. Since 1988, the International Registry of Werner syndrome had enrolled 130 molecularly confirmed WS cases from among 110 worldwide pedigrees. We now report 18 new mutations, including two genomic rearrangements, a deep intronic mutation resulting in a novel exon, a splice consensus mutation leading to utilization of the nearby splice site, and two rare missense mutations. We also review evidence for founder mutations among various ethnic/geographic groups. Founder WRN mutations had been previously reported in Japan and Northern Sardinia. Our Registry now suggests characteristic mutations originated in Morocco, Turkey, The Netherlands and elsewhere.
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ABSTRACT: Although still incomplete, we now have a remarkably detailed and nuanced picture of both phenotypic and genotypic components of the FA spectrum. Initially described as a combination of pancytopenia with a limited number of physical anomalies, it was later recognized that additional features were compatible with the FA phenotype, including a form without detectable malformations (Estren-Dameshek variant). The discovery of somatic mosaicism extended the boundaries of the FA phenotype to cases even without any overt hematological manifestations. This clinical heterogeneity was augmented by new conceptualizations. There was the realization of a constant risk for the development of myelodysplasia and certain malignancies, including acute myelogenous leukemia and squamous cell carcinoma, and there was the emergence of a distinctive cellular phenotype. A striking degree of genetic heterogeneity became apparent with the delineation of at least 12 complementation groups and the identification of their underlying genes. Although functional genetic insights have fostered the interpretation of many phenotypic features, surprisingly few stringent genotype-phenotype connections have emerged. In addition to myriad genetic alterations, less predictable influences are likely to modulate the FA phenotype, including modifier genes, environmental factors and chance effects. In reviewing the current status of genotype-phenotype correlations, we arrive at a unifying hypothesis to explain the remarkably wide range of FA phenotypes. Given the large body of evidence that genomic instability is a major underlying mechanism of accelerated ageing phenotypes, we propose that the numerous FA variants can be viewed as differential modulations and compression in time of intrinsic biological ageing.
Article: Spectral karyotyping and SNP microarray analysis define uniparental disomy (UPD) as a novel mutational mechanism in MSI- and CSI-colorectal cancers
Article: Helmut Baitsch (1921–2007)
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ABSTRACT: We discuss examples of the rare human genetic instability syndromes as they present themselves at the chromosome, telomere, and nuclear envelope level. Destabilization of the nuclear envelope due to mutations in the Lamin A/C gene lead to global impairments of the chromatin structure and gene expression with the fatal consequences observed in the Hutchinson-Gilford juvenile progeria syndrome. Patients with Dyskeratosis congenita have defective telomerase function. These patients exhibit a number of progeroid features, suggesting a causal connection between short telomeres and premature ageing. The most prominent example of the chromosomal instability syndromes is the Werner adult progeria syndrome where impaired helicase and exonuclease functions cause a multitude of (albeit superficial) similarities with the normal ageing process. A less well-know example is Fanconi anemia (FA) a multisystem disorder caused by biallelic mutations in one of at least 13 different genes which include the BRCA2 breast cancer gene. Unlike cells from any other human disorder, FA cells are uniquely sensitive to oxidative stress. In a situation of defective DNA repair, oxidative stress leads to accumulation of (unrepaired) DNA damage. Oxidative stress is the likely culprit of bone marrow failure, risk of neoplasia, and features of premature ageing in FA, rendering this rare disease into the only known human model of the free radical theory of ageing.
Article: Hypomorphic Mutations in the Gene Encoding a Key Fanconi Anemia Protein, FANCD2, Sustain a Significant Group of FA-D2 Patients with Severe Phenotype[Show abstract] [Hide abstract]
ABSTRACT: FANCD2 is an evolutionarily conserved Fanconi anemia (FA) gene that plays a key role in DNA double-strand-type damage responses. Using complementation assays and immunoblotting, a consortium of American and European groups assigned 29 patients with FA from 23 families and 4 additional unrelated patients to complementation group FA-D2. This amounts to 3%-6% of FA-affected patients registered in various data sets. Malformations are frequent in FA-D2 patients, and hematological manifestations appear earlier and progress more rapidly when compared with all other patients combined (FA-non-D2) in the International Fanconi Anemia Registry. FANCD2 is flanked by two pseudogenes. Mutation analysis revealed the expected total of 66 mutated alleles, 34 of which result in aberrant splicing patterns. Many mutations are recurrent and have ethnic associations and shared allelic haplotypes. There were no biallelic null mutations; residual FANCD2 protein of both isotypes was observed in all available patient cell lines. These analyses suggest that, unlike the knockout mouse model, total absence of FANCD2 does not exist in FA-D2 patients, because of constraints on viable combinations of FANCD2 mutations. Although hypomorphic mutations arie involved, clinically, these patients have a relatively severe form of FA.
- [Show abstract] [Hide abstract]
ABSTRACT: Chromosome breakage analysis following exposure of cultured cells to DNAcrosslinking agents has long been considered the 'gold standard' for the confirmation or exclusion of Fanconi anemia (FA). Cells containing DNA damage are arrested and accumulate, with a 4c DNA content, near the S/G2-phase border of the cell cycle. As manifestation of their impaired DNA damage response, FA cells typically express elevated G2-phase cell fractions which can easily be measured by flow cytometry. In our experience with more than 3,000 such analyses, at most 1 in 10 blood samples submitted for the exclusion or confirmation of FA yields a positive result. Compared to traditional chromosome breakage analysis, cell cycle testing is less demanding and offers the advantage of speed and low cost. We prefer flow cytometric cell cycle testing for the initial screening of patients, in whom unexplained thrombocytopenia, macrocytic aplastic anemia or other clinical findings require the exclusion of FA. In addition to its application in diagnostic screening, we here show that cell cycle analysis has become a valuable tool for the determination of clastogen sensitivity (such as required within the context of complementation studies), for the precise definition of cell cycle checkpoints, and for the quantitative determination of compartment-specific cell cycle delay or cell cycle arrest. Cell cycle analysis not only provides a reliable test system for the initial confirmation or exclusion of FA, but also serves as a highly informative tool for the comprehensive characterization of the FA cellular phenotype.
- [Show abstract] [Hide abstract]
ABSTRACT: The recessive disease Fanconi anemia (FA) is a prototype chromosome instability syndrome which shows a high level of spontaneous and induced chromosomal aberrations in combination with a significantly increased cancer risk. Thus, the underlying defect must be directly or indirectly involved in a fundamental cellular task of long-lived mammalian cells, the maintenance of genomic integrity. In addition to the delineation of the FA clinical and cellular phenotypes, prominent milestones in FA research include proof of extensive genetic heterogeneity, identification of (so far) 12 disease genes, and elucidation of the FA pathway involved in the repair of crosslinks at arrested replication forks. What is referred to as the FA/BRCA pathway represents only part of a complex network of protein-protein interactions which is far from being understood. The ultimate milestone in FA research would be the achievement of an individualized and curative therapy. Currently, hematopoietic stem cell transplantation is a promising but still high-risk therapy, and gene therapy is still at the experimental stage. Nonetheless, in a significant proportion of patients, a kind of 'natural gene therapy' can be observed which results from intragenic recombination or from compensating second site mutations. The elucidation of these somatic events and their underlying mechanisms can be considered a milestone in genetic research. The remarkable progress in FA research during the last 10-15 years was fostered by the foundation of FA patient support groups in many countries. These support groups are gratefully acknowledged as important motivational milestones in FA research.
- [Show abstract] [Hide abstract]
ABSTRACT: One out of four to five patients with Fanconi anemia experience a reversion or attenuation of their constitutional mutations during their lifetime. If the reversion event takes place in a bone marrow stem cell or in an early precursor cell of hematopoiesis, peripheral blood cell counts may gradually recover, leading to improved quality of life. At the beginning of this process, MMC testing will reveal a mixture of MMC sensitive and MMC resistant blood lymphocytes, but after several years MMC sensitive cells (the original FA-cells) may be completely replaced by the progeny of the reverted progenitor cell such that the confirmation of FA requires testing of patient fibroblasts. Molecular analysis reveals the presence of the disease causing biallelic mutations in fibroblast-derived DNA whereas MMC-resistant blood cells show only a single defective allele, explaining their phenotypic reversion. The mechanisms leading to revertant mosaicism include intragenic mitotic recombination (crossing over and gene conversion), back mutation, and compensatory second site mutations. Evidence for each of these mechanisms has been obtained in mosaic FA-patients, but their molecular details are not fully understood. Compound heterozygosity facilitates some of these mechanisms, but reversions have also been observed in homozygous patients. Patients belonging to subtypes FA-A, FA-C, FA-D1, FA-D2 and FA-L have developed revertant mosaicism, with subtypes FA-A and FA-D2 being most frequently involved. Even though the phenomenon of revertant mosaicism has been well documented in FA, there still are many questions: we do not know whether the progeny of a single reverted blood stem or progenitor cell would be able to sustain lifelong hematopoiesis, whether revertant mosaicism provides protection against hematopoietic malignancy, or whether it would be possible to deliberately increase the rate of somatic reversions in order to improve chances for 'natural gene therapy'. Prospective and long-term follow-up studies are needed to answer these questions.
Article: Successful bone marrow transplantation in a patient with DNA ligase IV deficiency and bone marrow failure. Orphanet J Rare Dis 2:5[Show abstract] [Hide abstract]
ABSTRACT: DNA Ligase IV deficiency syndrome is a rare autosomal recessive disorder caused by hypomorphic mutations in the DNA ligase IV gene (LIG4). The clinical phenotype shows overlap with a number of other rare syndromes, including Seckel syndrome, Nijmegen breakage syndrome, and Fanconi anemia. Thus the clinical diagnosis is often delayed and established by exclusion. We describe a patient with pre- and postnatal growth retardation and dysmorphic facial features in whom the diagnoses of Seckel-, Dubowitz-, and Nijmegen breakage syndrome were variably considered. Cellular radiosensitivity in the absence of clinical manifestations of Ataxia telangiectasia lead to the diagnosis of DNA ligase IV (LIG4) deficiency syndrome, confirmed by compound heterozygous mutations in the LIG4 gene. At age 11, after a six year history of progressive bone marrow failure and increasing transfusion dependency the patient was treated with matched sibling donor hematopoietic stem cell transplantation (HSCT) using a fludarabine-based conditioning regimen without irradiation. The post-transplantation course was uneventful with rapid engraftment leading to complete and stable chimerism. Now at age 16, the patient has gained weight and is in good clinical condition. HSCT using mild conditioning without irradiation qualifies as treatment of choice in LIG4-deficient patients who have a matched sibling donor.
- [Show abstract] [Hide abstract]
ABSTRACT: Bladder carcinomas frequently show extensive deletions of chromosomes 9p and/or 9q, potentially including the loci of the Fanconi anemia (FA) genes FANCC and FANCG. FA is a rare recessive disease due to defects in anyone of 13 FANC genes manifesting with genetic instability and increased risk of neoplasia. FA cells are hypersensitive towards DNA crosslinking agents such as mitomycin C and cisplatin that are commonly employed in the chemotherapy of bladder cancers. These observations suggest the possibility of disruption of the FA/BRCA DNA repair pathway in bladder tumors. However, mutations in FANCC or FANCG could not be detected in any of 23 bladder carcinoma cell lines and ten surgical tumor specimens by LOH analysis or by FANCD2 immunoblotting assessing proficiency of the pathway. Only a single cell line, BFTC909, proved defective for FANCD2 monoubiquitination and was highly sensitive towards mitomycin C. This increased sensitivity was restored specifically by transfer of the FANCF gene. Sequencing of FANCF in BFTC909 failed to identify mutations, but methylation of cytosine residues in the FANCF promoter region was demonstrated by methylation-specific PCR, HpaII restriction and bisulfite DNA sequencing. Methylation-specific PCR uncovered only a single instance of FANCF promoter hypermethylation in surgical specimens of further 41 bladder carcinomas. These low proportions suggest that in contrast to other types of tumors silencing of FANCF is a rare event in bladder cancer and that an intact FA/BRCA pathway might be advantageous for tumor progression.
- [Show abstract] [Hide abstract]
ABSTRACT: The International Registry of Werner syndrome (www.wernersyndrome.org) has been providing molecular diagnosis of the Werner syndrome (WS) for the past decade. The present communication summarizes, from among 99 WS subjects, the spectrum of 50 distinct mutations discovered by our group and by others since the WRN gene (also called RECQL2 or REQ3) was first cloned in 1996; 25 of these have not previously been published. All WRN mutations reported thus far have resulted in the elimination of the nuclear localization signal at the C-terminus of the protein, precluding functional interactions in the nucleus; thus, all could be classified as null mutations. We now report two new mutations in the N-terminus that result in instability of the WRN protein. Clinical data confirm that the most penetrant phenotype is bilateral ocular cataracts. Other cardinal signs were seen in more than 95% of the cases. The median age of death, previously reported to be in the range of 46-48 years, is 54 years. Lymphoblastoid cell lines (LCLs) have been cryopreserved from the majority of our index cases, including material from nuclear pedigrees. These, as well as inducible and complemented hTERT (catalytic subunit of human telomerase) immortalized skin fibroblast cell lines are available to qualified investigators.
Article: Radiation-induced DNA damage and repair in peripheral blood mononuclear cells from Nijmegen breakage syndrome patients and carriers assessed by the Comet assay[Show abstract] [Hide abstract]
ABSTRACT: Nijmegen breakage syndrome (NBS) patients and carriers are predisposed to malignancy and are often treated with X-irradiation. In the present study, the single-cell gel electrophoresis (Comet) assay was used to examine radiation-induced DNA damage and repair in peripheral blood mononuclear cells from NBS patients (n=13) and carriers (n=36) of six unrelated families. Cells from apparently healthy donors (n=10) and from breast cancer patients with normal clinical radiosensitivity (n=10) served as controls. Cells were irradiated with 5 Gy of X-rays and assayed for initial DNA damage and for residual DNA damage after 40 min of repair; the kinetics of DNA repair also was estimated. In addition, the nuclear area of unirradiated cells was extracted from the Comet data. The initial radiation-induced DNA fragmentation indicated that cells from members of two out of six NBS families were significantly more sensitive to X-irradiation than cells from the controls. Cells from four NBS families had longer DNA repair half-time values, while cells from five NBS families had significantly increased residual DNA damage following repair. The mean nuclear area of unirradiated cells processed in the Comet assay was 1.3-fold higher in cells from all NBS families than in the controls (P<0.05). Notably, the Comet assay parameters (initial and residual DNA damage and the repair kinetics) of irradiated NBS cells predicted the carrier status of the majority (86%) of blindly tested individuals. The prediction of NBS status was higher if the nuclear area of unirradiated cells was used as the endpoint. The results of this study suggest that the impaired radiation response of NBS cells should be taken into account if radiotherapy of NBS patients and carriers is required.
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ABSTRACT: Ataxia telangiectasia (AT) is an autosomal recessive multisystem disorder with increased radiosensitivity and cancer susceptibility. The responsible gene (ATM) consists of 66 exons and a coding region of 9171 bp which precludes direct sequencing as a screening assay for confirmation or exclusion of the clinical suspicion of AT. Peripheral blood mononuclear cells of 330 patients referred for the exclusion of AT were exposed to ionizing radiation (IR) and incubated for 72 h in the presence of phytohemagglutinin. Using bivariate BrdU-Hoechst/ethidium bromide flowcytometry, the following cell cycle parameters were ascertained: (1) proportion of non-proliferating (G0,G1) cells as a measure of mitogen response, (2) proportion of first-cycle G2-phase cells relative to the growth fraction (G2/GF) as a measure of radiosensitivity. Of the cases tested, 94.2% could be unequivocally assigned either to the AT-negative or the AT-positive group of patients. Of the AT-positive cases, 11 were confirmed by ATM mutation analysis. Nineteen cases presented with non-conclusive results, mostly due to poor mitogen response; however, a combination of cell-cycle data with serum AFP concentrations led to the exclusion of AT in all but two of the uncertain cases. Substitution of ionizing radiation by the radiomimetic bleomycin was additionally tested in a small series of patients. We conclude that cell-cycle testing complemented by serum AFP measurements fulfills the criteria as a rapid and economical screening procedure for the differential diagnosis of juvenile ataxias.
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ABSTRACT: Fanconi anemia (FA) is a rare recessive disease that reflects the cellular and phenotypic consequences of genetic instability: growth retardation, congenital malformations, bone marrow failure, high risk of neoplasia, and premature aging. At the cellular level, manifestations of genetic instability include chromosomal breakage, cell cycle disturbance, and increased somatic mutation rates. FA cells are exquisitely sensitive towards oxygen and alkylating drugs such as mitomycin C or diepoxybutane, pointing to a function of FA genes in the defense against reactive oxygen species and other DNA damaging agents. FA is caused by biallelic mutations in at least 12 different genes which appear to function in the maintenance of genomic stability. Eight of the FA proteins form a nuclear core complex with a catalytic function involving ubiquitination of the central FANCD2 protein. The posttranslational modification of FANCD2 promotes its accumulation in nuclear foci, together with known DNA maintenance proteins such as BRCA1, BRCA2, and the RAD51 recombinase. Biallelic mutations in BRCA2 cause a severe FA-like phenotype, as do biallelic mutations in FANCD2. In fact, only leaky or hypomorphic mutations in this central group of FA genes appear to be compatible with life birth and survival. The newly discovered FANCJ (= BRIP1) and FANCM (= Hef ) genes correspond to known DNA-maintenance genes (helicase resp. helicase-associated endonuclease for fork-structured DNA). These genes provide the most convincing evidence to date of a direct involvement of FA genes in DNA repair functions associated with the resolution of DNA crosslinks and stalled replication forks. Even though genetic instability caused by mutational inactivation of the FANC genes has detrimental effects for the majority of FA patients, around 20% of patients appear to benefit from genetic instability since genetic instability also increases the chance of somatic reversion of their constitutional mutations. Intragenic crossover, gene conversion, back mutation and compensating mutations in cis have all been observed in revertant, and, consequently, mosaic FA-patients, leading to improved bone marrow function. There probably is no other experiment of nature in our species in which causes and consequences of genetic instability, including the role of reactive oxygen species, can be better documented and explored than in FA.
- [Show abstract] [Hide abstract]
ABSTRACT: To explore the potential of flow cytometry in the prenatal exclusion or confirmation of Fanconi anemia (FA). Indications for prenatal diagnosis were (1) FA-negative family history, but suspicious ultrasound findings such as radial ray aplasia, (2) FA-positive family history, but without knowledge of the affected gene and/or mutation. Amniotic fluid (AF) cell cultures and umbilical cord (UC) blood cultures were assayed for typical cell cycle changes (G2-phase accumulations) without and with mitomycin C (MMC) treatments using single- and dual-parameter (BrdU-Hoechst) flow cytometry. Single-parameter flow cytometry correctly identified 2 positive and 9 negative cases on the basis of MMC sensitivity of cultivated AF cells. Likewise, 8 negative and 2 positive cases were correctly predicted using bivariate flow cytometry of 72-hour UC blood cultures. In contrast, bivariate flow cytometry applied to AF cells grown in the presence of bromodeoxyuridine (BrdU) yielded false-positive and false-negative results. Single-parameter flow cytometry of AF cell cultures and bivariate flow cytometry of UC cell cultures have the potential to correctly predict the affected status in cases at risk for FA, whereas bivariate flow cytometry proved unreliable when applied to BrdU-substituted AF cell cultures. Cases with a low a priori risk (e.g. sonographic finding of radial ray abnormalities and negative family history) would benefit most from flow cytometry as a rapid and economical prenatal screening procedure.
Top Journals
University of Wuerzburg
Würzburg, Bavaria, Germany
- • Institute for Human Genetics
- • Department of Biochemistry
- • Institute for Molecular Infection Biology
United States Department of AgricultureWashington, Washington, D.C., United States
Justus-Liebig-Universität GießenGieben, Hesse, Germany
Universität Hamburg
Hamburg, Hamburg, Germany
- Institute for Occupational and Maritime Medicine
University of Washington Seattle
Seattle, Washington, United States
- Department of Pathology


text:
~BH~ Hell's Maw
Credits & Info
- Date
- 01/28/2008
- File Info
- Song
- 2 min 4 sec
- Score
- 4.40 / 5.00
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Heard in 3 Entries!
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You may not use this work for commercial purposes without making specific arrangements with the artist UNLESS your work is a web-based game or animation, in which case you may use this freely.
- Score:
- Rated 4.40 / 5 stars
- Plays & Downloads:
- 8,559 Plays | 1,211 Downloads
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- Genres:
- Electronic - Techno
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Author Comments
Rated 5 / 5 stars
soo sick
loved it man. one of my favorite songs from this site
Rated 5 / 5 stars
very good loop
it's very very nice I just wished it's more of a loop I mean you can tell it ended and started again.
Rated 5 / 5 stars
most likely the best song i have ever heard... EVER!
Deserves higher than 10 :p shame ng wont let people vote above 10
Rated 5 / 5 stars
This was actually the first song of yours I heard, stumbled across it while on youtube looking at some of f-777's stuff the other day. I gota say, It's pretty amazing, also like the loop, I've been sitting here browsing a forum for like 20 minutes with this is playing in the background, hardly even noticed it was looping.
Rated 4.5 / 5 stars
could use mabey a guaitar, awshome though


text:
Stars by inkandstardustWatch
©2012-2016 inkandstardust
The Eleventh Doctor, Closing Time, Doctor Who
i love this quote. this one made me cry...
one word comes to mind when reading this:Marvelous! and I guess awwwww too but strictly speaking that isn't a word
This is one of my favorite Eleven scenes of all time.
This is beautiful. May I use this in one of my stories? I'll give you credit for reminding this to me. xD (Doctor Who ftw~)
Can I steal, please?
Sorry? What do you mean?
Yeah, this scene definitely made my heart cry.
this is where I broke down sobbing. Drenching my bowl of popcorn. I felt like he betrayed us by giving up. GAH. 11 is SO GOOD! 9 and 10 were nice, but for some reason... 11 just.... i don't know how to describe it.
I can't necesarrily 100% relate to the message, but I still think this is a pretty image with a positive message. You've earned my favourite.
I don't even watch Doctor Who (Though I might soon) and this is beautiful.
i dreamt of stars as well
congrats for front page slot~love this so much!
Was this when Older Amy was talking to Younger Amy?
I believe someone may have already replied to this, but it was when the Doctor was talking to Alfie Owens in Closing Time. I usually put who has said what in the desc. x
This was the Doctor talking to Craig's baby son.
Your quote things are THE most beautiful things ever. I really just want to print them all off and stick them around my room. <3
Thank you! You may use a lot of ink doing so though!
It's my Dad's ink, I'm sure he won't mind xD
Aha! Then in the words of the Doctor in this very episode...'But, then again, it's your parents cash, they'd only waste it on boring stuff. Like lamps and vegetables!'
YES Haha, oh you are brilliant!And we definitely don't need more lamps and vegetables in this house, thank you very much!:')
lloooovvveee these!
Great quote as usual. Keep up the awesome work !


text:
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Ode to Solitude by idaniphotographyWatch
©2010-2016 idaniphotographyMature Content
Beautiful light.
so beautiful....
it reminds me of Edward Hopper and all its solitude concept in big cities... I've always said you're a master in erotic portraits, but this time I can also say you're a versatile master of creativity... And, if I understand a little bit your mind... I know you're thinking a lot of creations about your sweet daughter, when she'll grow up.
Wish you all the best (to you, Aisii and your little treasure). You're the great artist and maybe the father I'll never be.
Wish you all the best (to you, Aisii and your little treasure). You're the great artist and maybe the father I'll never be.
foarte tare,bravo!
Very interesting -- lovely light, colours and angles. Fun trying to work out a backstory for the scene! The three-dimensional depth and intriguing scene makes this a quirky and eye-catching desktop-wallpaper for my PC too!
Very interesting composition.
I can't really put my finger on why, but I really like this image. There is just something about it. I dig the green walls for sure!
superb modelul, tot cadrul pare sa il scoata in evidenta. Si in oarecare masura este simetrica compozitia, iar ca poveste pune in discutie lumina.
I LOVE IT... very friggin' cool, VERY friggin' cool.
nice green
Fantastic work!
Very Nice!
I particularly love the angle in this. Makes me wonder who is looking at her and what the story behind the photograph is. I feel like all the components in the picture give it depth, especially the cord. The nudity does not seem unnecessary, it's as if we can get a wisp of truth and sincerity behind the story of her life. I also really like the tones, they're really warm which don't give it that creepy feeling. I like that I can see the light in the other room and it's a blue wall, I feel that they give a significance to the fact that she's alone.
excellent work!
~ b e a u t i f u l ~
awesome colours!!!


text:
Conrad Industries
Conrad Industries to Release Quarter Results
Conrad Industries, Inc. plans to release its first quarter earnings during the evening on Wednesday, May 5, 2004. Management of the Company will host a conference call on Thursday, May 6, 2004 at 9:30 a.m. CST, to discuss the Company's financial results for the quarter ended March 31, 2004.
Conrad Industries Reports Profit, New Orders in Annual Results
US-bsed shipbuilder Conrad Industries records profit, new orders for barges, cargo/passenger ferry, in 2011 results Conrad Industries, Inc. has announced its fourth quarter and twelve months 2011 results and the addition of new business during the first quarter totaling $61.8 million. New business added during the first quarter of 2012 includes the signing of new contracts and sales of stock barges which brings estimated current backlog to approximately $68.7 million, compared to $47
Conrad Appoints Hernandez COO and Announces Resignation of CFO Derbes
Conrad Industries, Inc. announced that the Board of Directors has named Cecil A. Hernandez as its Executive Vice President and Chief Operating Officer, effective immediately. Mr. Hernandez will remain a member of the Board, a position he has held since March 1998. Mr. Hernandez was Conrad's former Chief Financial Officer between January 1, 1998 and September 30, 2002 and most recently served as President of Summit Management Group LLC.
Conrad Wins $8.9M Towboat Contract
Conrad Industries, Inc. won an $8.9 million contract by the United States Army Corps of Engineers to design and build a 144-ft., 3,300-hp, ABS-Classed welded steel towboat. When delivered, the vessel's primary mission will be the support of the MAT Sinking Unit revetment operations on the Mississippi River for the Vicksburg District of the United States Army Corps of Engineers
GE to Supply for Conrad
GE Marine announced it will provide Conrad Industries, Inc., , with two 8 cylinder V228 medium-speed diesel engines through NREC Power Systems, a GE authorized dealer. The engines will power a passenger/vehicle ferry designed by Alan C. McClure Associates, Inc. and Schuller & Allan LLC, both of . The ferry is being built by Conrad Industries for the Texas Department of Transportation, Austin. The 264 x 66 x 15-ft
Conrad Announces 2014 Q1 Results
Conrad Industries, Inc. announced its first quarter 2014 results. For the quarter ended March 31, 2014, Conrad achieved net income of $6.4 million and earnings per diluted share of $1.08 compared to net income of $5.9 million and earnings per diluted share of $0.99 during the first quarter of 2013. Conrad's backlog was $155.8 million at March 31, 2014 compared to $152.9 million at December 31, 2013 and $125.5 million at March 31, 2013.
Conrad Welcomes New Facility
Conrad Industries held a ribbon cutting ceremony yesterday at its new repair and conversion facility in Amelia, La. Several local politicians were on hand including, Bill Cefalu, St. Mary Parish President; Representative Jack Smith, Louisiana District 50; Representative Carla Dartez, Louisiana District 51; State Senator D. A. "Butch" Gautreaux, Louisiana District 21; Dr. Tim Tregle, Mayor of Morgan City; and Emile Babin, President & CEO of the St
Conrad Shipyard Delivers First of Six Liftboats
Morgan City, Louisiana Conrad Industries, Inc. announced that Offshore Marine Contractors, Inc. took delivery of the first of six liftboats under construction at Conrad Shipyards. It was a beautiful spring day in South Louisiana as Avis Bourg III along with his wife Tiffany and their daughter Lacie, the namesake, christened the 175' Class liftboat, "Lacie Bourg". Toby Eymard stated "We are very excited about putting this vessel into
Conrad Industries, Inc. Hosts National Safety Seminar
Conrad Industries, Inc. hosted the 2004 Shipbuilders Council of America Fall Safety Seminar at their Morgan City, LA facility, September 22-23. Attendees heard presentations on current shipyard health and safety issues, including CO2 Total Fire Protection Systems, Rigging Safety, and Fall Protection Systems. The Safety Seminar takes place twice a year at SCA member facilities to share current shipyard safety and health information
Conrad Industries Ratchet Up Q2 2013 Profits
Conrad Industries, Inc., headquartered in Louisiana, announce its second quarter and six months 2013 financial results and backlog at June 30, 2013. For the quarter ended June 30, 2013, Conrad had net income of $6.1 million and earnings per diluted share of $1.02 compared to net income of $5.3 million and earnings per diluted share of $0.87 during the second quarter of 2012. The company had net income of $12.0 million and earnings per diluted share of $2
MARAD Approves Title XI Loan for Gray Offshore
A $12 million Title XI loan guarantee supporting the recent construction of three oceangoing deck barges was recently approved by the U.S. Maritime Administration (MARAD). The three barges, Julius, Cordie and Gwendolyn, were built by Conrad Industries for barge leasing company Gray
'Double Skin' Oil Barge Delivered to Vane Brothers
The Vane Brothers Company has taken delivery of a 55,000 BBL double hull oil barge, Double Skin 509A. Bristol Harbor Group, Inc. (BHGI) was contracted by the builder Conrad Industries to develop the design of the 361' x 62' x 24.5', 55,000 BBL double skin tank barge
Danos Appoints 3 to Sr. Positions
Danos announces the hiring of Marc Distefano, John Danos and Jack Roszelle to leadership positions with the company. "We welcome Marc, John and Jack to the Danos team," said CEO and President Hank Danos. "Their expertise and experience will help us ensure we are
New Tug Delivered to Vane Brothers
The Vane Brothers Company, a marine transportation provider headquartered in Baltimore, Md., has taken delivery of the Elizabeth Anne, the first in a new series of 4,200-horsepower tugboats. Vane Brothers has ordered a total of eight Elizabeth Anne Class towing vessels through St
Where there are American Waters, there is Harley
The maritime community in the United States has watched with interest as Harley Marine Services has expanded from the West Coast to the East and Gulf Coasts and now the Inland Waterways. As with other expansions, carried out by Chairman and CEO Harley Franco, this one
Conrad Industries' Performance Rides High in Q3 2013
Morgan City, Louisiana-based Conrad announce positive third quarter 2013 results, and is to pay a special cash dividend of $2.00 per share. For the quarter ended September 30, 2013, Conrad had net income of $6.5 million and earnings per diluted share of $1.09 compared to net income of $4
Conrad Industries 2013 Profit Slip Ameliorated by New Business
Morgan City, Louisiana, shipbuilder and ship repairer Conrad Industries, has announced its fourth quarter and twelve months 2013 financial result, adding that it has acquired new business during the first quarter of 2014 totalling $67.3 million. Q4 2013
Conrad Reports Strong Q2 Results, Backlog
Conrad Industries, Inc. announced its second quarter and six months 2014 financial results and backlog at June 30, 2014. For the quarter ended June 30, 2014, Conrad had net income of $6.8 million and earnings per diluted share of $1.14 compared to net income of $6
Conrad 3Q 2014 Net Slips
Conrad Industries, Inc.announced today its third quarter and nine months 2014 results and backlog. For the quarter ended September 30, 2014, Conrad had net income of $4.5 million and earnings per diluted share of $0.74 compared to net income of $6
NASA Recognizes Conrad for Barge Conversion
Conrad Industries, Inc. has received the NASA Space Flight Awareness Supplier Award based on its performance with the conversion of the NASA Pegasus barge. The annual award honors outstanding performance by hardware, software or service suppliers who support NASA human space flight
WesPac to Build N. America's First LNG Bunker Barge
WesPac Midstream LLC (WesPac), a provider of energy infrastructure and liquefied natural gas (LNG) solutions, and its affiliate Clean Marine Energy LLC (CME), the global facilitator of tailored solutions for Emission Control Area (ECA) compliance
Solving the LNG Propulsion Puzzle
The last piece of the LNG infrastructure puzzle, in the form of North America's first LNG bunker barge, falls into place at Conrad's Orange, Texas Shipyard. With continued debate over new emissions standards and compliance dates hanging over the heads of operators in the Emission
Conrad Announces Management Team Changes
Conrad Industries, Inc. announced the appointment of Scott J. Theriot as Executive Vice President and Chief Operating Officer. Johnny Conrad, President and Chief Executive Officer, said, "Scott has been in the shipyard business since 1976 in various positions spending the majority
Conrad Industries Appoints Leonard as VP
Conrad Industries, Inc. announced the appointment of Rene J. Leonard as Vice President of Business Development and Engineering. "Rene has been in the shipyard business over 25 years in various capacities including naval architect, project engineer, program manager
Conrad Industries 2Q Revenue Shrinks
Conrad Industries, Inc. announced today its second quarter and six months 2015 financial results and backlog at June 30, 2015. For the quarter ended June 30, 2015, Conrad had net income of $1.2 million and earnings per diluted share of $0.21 compared to net income of $6


text:
the most amazing thing in the whole universe way better then anything that any other urban dictionary name says even a phillip! ck has the biggest widest dick in the whole universe and god is jealous of him. hes the best thing ever!!!!!!
phillip: hey look its cesar
larry: shut up! we aren't good enough to say his name!
larry: shut up! we aren't good enough to say his name!
作者 ckthegreatking7 2014年8月09日
Someone who is crazy.
That girl is so cesar.
作者 smartyypartyy 2015年4月06日
the worst type of person on earth, usually fat with a small dick.
"whose that?"
"Oh, that's just Cesar"
"Oh, that's just Cesar"
作者 Epiiiicccc 2015年1月05日
Usally a short blone indivisual with lowself of steam with a very unusual forehead size...tries to impress girls with his tight shirts on but he is really fat and not muscular has a small penis
Cesar isn't even buff he treys to look buff with his tight muscle shirts
作者 Therealmeaning555 2014年3月11日
mexican jew that is so cheap he can't even pay for the company he bought. when he gets angry his eyes bulge out of his skull and his teeth grind like clutch. he beats his chest like a gorila then goes home and beats his gorilla wife. he thinks hes a big shot in his big dumb red truckkk but nobody gives a fuckkk. hes got more kids than a sock got holes. he wants a fortune but all he got was a cookie in emily.
Employee: yo Cesar how bout a coffee?
Cesar: LOL I CANT AFFORD THAT GET OUTTA MY OFFICE
Cesar: LOL I CANT AFFORD THAT GET OUTTA MY OFFICE
作者 TTom 2012年5月07日
A person who is a bit queerish and that can be total asshole. He sucks at tennis and licks my balls for a living.
Oh man, I don't want to hang out with that guy! He is a total Cesar!
作者 JRTee Man 2013年6月12日
A smug arrogant prick who impregnates his underage girlfriend and then has to give up his Ivy League beaner scholarship to come back home and get a job he isn't qualified for at the company his beaner-baby-momma's father works at.
Man, Cesar really screwed up when he got that chick knocked up, but it will be ok because soon he will be the boss of all these people that hate him at his new job.
作者 Servilius Casca 2012年5月25日


text:
© 2016 Need Supply CompanyAll Rights Reserved
Sign up to get notified when this product is back in stock
Free Standard Domestic Shipping and Free Returns on Orders of $75 or More
Classic and cozy knit sweater with vintage-inspired styling. Features rounded neckline, ribbed trim, dropped shoulders for casual, relaxed fit, and all over stitched dot pattern.
• Soft knit sweater
• All over small dot pattern
• Dropped shoulders
• Casual, comfortable fit
• 55% Acrylic, 30% Cotton, 15% Wool
• Dry clean only
View Size Chart
22" bust
22.5" shoulder to shoulder
25" shoulder to hem
18.5" sleeve length
Measurements taken from size small
Model wears size small. Model is 5'10
View Size Chart
3100 West Cary Street
Richmond, VA 23221
© 2016 Need Supply Company—All Rights Reserved


text:
Best Brazilian Restaurant (2003)
Panorama Restaurant
Drive east on Atlantic Boulevard and evidence of the Brazilian enclave of more than 20,000 leaps out at you, from flag symbols on hair salons, cafés, and newsstands to the Saturday special called feijoada served up by Panorama Restaurant. The eatery has been preparing top loin steaks such as picanha e alcatra panorama, picanha a cavalo, and other favorites such as oxtail stew and tripe for a largely Brazilian clientele for nearly a decade. The only other thing that may divert your attention from the waft of seasonings coming from the kitchen is the large-screen TV in the front that broadcasts the jogo bonito -- the beautiful game that is Brazilian soccer.
More Awards from This Winner
Location Details
900 E. Atlantic Blvd.
Pompano Beach FL 33062
Pompano Beach FL 33062
More Food & Drink Awards
Phil Kappesmanages his father's popular sandwich place, Spada's Original Hoagies, in Lauderdale-by-the-Sea
Best Caesar SaladDelacaseas
Best RibsWings N Curls
Best FalafelSawaf's Restaurant


text:
Commissaires are the sports officials that supervise bicycle races in each cycling discipline. Their responsibilities at bike races are similar to those of the referees or umpires in other sports.
All races at the provincial and regional level in BC are supervised by one or more Commissaires, who generally have the following responsibilities:
- Supervise the behavior of the riders,
- Apply penalties (such as warnings, fines, relegation, or disqualification) if appropriate for infractions of the rules,
- Judge the start and finish of each race, and
- Perform backup timekeeping.
Commissaires are semi-professional volunteers who, when appointed to provincial and regional level races not held by their own club, are paid an honorarium of between $75 and $130 / race day, plus travel expenses.
If you are interested in becoming a commissaire contact Claire Bonin for more details.
View our calendar for upcoming commissaire courses.
Commissaire Certification Process and Levels
Provincial 'C' Commissaire
Provincial 'B' Commissaire
Provincial 'A' Commissaire
Provincial 'A' Commissaire Exam
Cycling Canada has developed a standardized exam for commissaires who want to achieve their Provincial A status in each discipline. Each exam contains thirty questions; commissaires will have one hour to complete them. The exams are broken down into categories (ie. general regulations, equipment and clothing, etc.), and questions are randomly selected from a pool of questions for each category.
These evaluations will be offered for a cost of $10 per participant. Login's must be created by Cycling Canada for each individual taking the exam. Before the course, instructors will be given directions for administration.
If you are interested in using these exams for your Provincial A course, please contact firstname.lastname@example.com for details.
National Commissaire
International Commissaire


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No egg used. Location is 5 minutes from the airport. Removed as a duplicate listing of this one. Price: Inexpensive more-less
JL. Bybass Ngurah Rai 88C (Depan Pom Bensin, Tuban Kuta Bali)
Bali, Indonesia
Bali, Indonesia
No reviews yet.
- Link to this page from your site. Entry info.
- Return to Bali Vegetarian Restaurants & Health Food Store Listings
- Has REMOVED: Derasa closed, shut down, moved, or changed? Please use the Update Form.


text:
Item 507244
Kwik Sew Leotards, Leggings and Shorts Pattern
Product Actions
Additional Information
Kwik Sew Pattern # 2724Sizes: 4-5-6-7
The leotards, leggings and shorts are designed for two-way stretch fabric with 75% stretch. We suggest cotton Lycra®, nylon Lycra®, swimwear fabrics or stretch velvet with Lycra®.
The capri length leggings and shorts do not have side seams and they have elastic at the waist. The leotards have a scoop neckline and all of the outside edges are finished with elastic. View B has princess lines and side panels with piping from contrast fabrics.