text:
Mimi Neal '12
Since dropping her first two collegiate squash matches to highly ranked Cornell and Stanford, Bates first-year Mimi Neal (Danvers, Mass.) has won seven straight matches at the No. 6 position, including four last week during the Bobcat women's squash team's 3-1 week.
Neal, who also had a standout season on the Bates golf team in the fall, swept her opponents from Vassar, Wesleyan, Mount Holyoke and Franklin & Marshall last week, all by 3-0 scores. Dropping only three total points against Wesleyan and one against Mount Holyoke, her aggregate match score for the week was 108-3. She continued her run this week with a 3-0 win against Colby in which she again didn't allow a single point.
Neal and the No. 12 Bates women's squash team (4-5) play at No. 5 Yale on Saturday, then take on No. 25 Connecticut College on Sunday at Yale.
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5 tips on how to make sure you have the keys to the content marketing kingdom.
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EMF - the Forum of e-Excellence's curator insight, January 20, 6:07 AM
This is a new blog on the requirements for multilingual knowledge systems.
malek's curator insight, February 6, 6:30 PM
traditional social networks are now encouraging brands to mix their storytelling efforts with more social video features.
Marc Kneepkens's curator insight, February 7, 11:00 AM
#Videos are definitely becoming more important in social media. More apps and tools are becoming available.
Nik Peachey's curator insight, January 23, 2:10 AM
This looks a bit messy but has some useful features. It can pull out colocations and create close tests, so can be a real time saver.
Julia Polshina's curator insight, January 23, 3:55 AM
Some more tools to help with developing writing skill.
Monica Jan's curator insight, January 23, 6:19 PM
This might be used as a useful writing analysis tool to find out the features of EFL writing.

subset: commoncrawl


text:
Deuteronomy 4:15-19New International Version (NIV)
Idolatry Forbidden
15 You saw no form of any kind the day the Lord spoke to you at Horeb out of the fire. Therefore watch yourselves very carefully, 16 so that you do not become corrupt and make for yourselves an idol, an image of any shape, whether formed like a man or a woman, 17 or like any animal on earth or any bird that flies in the air, 18 or like any creature that moves along the ground or any fish in the waters below. 19 And when you look up to the sky and see the sun, the moon and the stars—all the heavenly array—do not be enticed into bowing down to them and worshiping things the Lord your God has apportioned to all the nations under heaven.
Cross references:
New International Version (NIV)
Holy Bible, New International Version®, NIV® Copyright ©1973, 1978, 1984, 2011 by Biblica, Inc.® Used by permission. All rights reserved worldwide.
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text:
There are many little-used approaches that result in a better highway or bridge project. Among the benefits of such approaches are that they're faster, safer, have less impact on traffic, provide better quality, and at less cost.
A key to getting innovations into wider use is telling people about them. Here are several tools for spreading the word on innovations.
Providing assistance to general industry in promoting late phase technology development
Highways for LIFE provides State DOTs with funding for construction of projects using one or more innovations that the agency has rarely used previously.
The methods and priority given to the actual process for getting innovations and new technologies moved into common practice must be improved in order to accelerate their delivery. Test cases, called "vanguard technologies" have demonstrated excellent results.
PowerPoint Version (447 kb)
Welcome to the webinar sponsored by Highways for LIFE on Market Research for FHWA Innovations. For the next hour and a half we'll be discussing the role FHWA has in the technology and innovation deployment effort. We'll talk about some basic concepts of market research, different sorts of data analysis, some of the new techniques in market research and hear about how one transportation agency has used market research as a tool in decision making.
Mia Zmud, NuStats
Overview : Market Research for Hwy Technologies
John Cashmore, VP,Ascendancy Research
What's New in Market Research Techniques
Chris McMahon, Director of Market Research, Mn/DOT
One Agency's Use of Market Research in Transportation Decision-Making
First, let me introduce our speakers. After they've concluded, we will have some time for Q&A, so hold your comments until then. Our first speaker is Mia Zmud. Mia is a director of NuStats, a market research firm headquartered in Austin, Texas. NuStats specializes in market research for the transportation industry, and they have several decades of experience in the field. Most recently, the firm completed work – with Mia as Project Director - on an NCHRP Project entitled, "Putting Customer Research into Practice." The subheading is "Guidelines for Conducting, Reporting, and Using Customer Surveys Related to Highway Maintenance Operations." You may also be familiar with the recently completed NCHRP report Entitled, "Communication Matters – Communicating the Value of Transportation Research." NuStats led the development of that document, as well as the workshop that accompanied it. John Cashmore is vice president of Ascendancy Research, a firm located in Minnesota. His background is primarily in the building materials industry, and he'll give us insight on those new developments we spoke of. Finally, Chris McMahon with the Minnesota DOT will tell us about that agency's market research program and how their commissioner, Tom Sorel – whom many of you know from his days as an FHWA leader –has used market research to ensure that what Mn/DOT delivers is meeting the needs of their citizens.
First, though, let's take a brief overview of how market research, or marketing research as it is sometimes called, is typically used in transportation agencies. One chief use is customer satisfaction surveys. Our agency has, over the past several years, done periodic nationwide traveler opinion and perception surveys to assess customers' hot buttons. Next: Of course, whenever there are federal funds spent on highway projects, public meetings are required. This is a form of market research, although typically not scientific, in that whoever is most vocal often gets the most response. True market research tries to get a true gauge for the feelings of all the targeted audience. And, then, of course, state agencies often use state-wide surveys to show the public's support for voter initiatives and other decision-making elements.
But what we're looking at today, especially, is the value of market research in the area of getting new technologies and innovations into use. This is an application of market research that many state DOTs would not use as much as we do, because we have a unique role in the highway community. In fact our official mission is to "Improve Mobility of our Nation's Highways Through National Leadership, Innovation and Program Delivery." So what can such market research offer? Well, if you're trying to prepare a marketing or implementation plan for how you will go about pushing an innovation, good market research can provide you with some or all of these: discovery of previously unknown information or validation of things you assumed (or elimination of any false assumptions), it can help you decide how best to go about deploying the technology such as determining what sort of promotional efforts to use. If, for instance, you find that a key decision-maker audience is not very technically focused, such as perhaps CEOs, you may want to develop a short video or one-page flyer that describes the technology in the simplest terms. On the other hand, if you give such a marketing communication piece to someone who IS very technically savvy, you may insult them, or they may laugh at your simplistic approach . And, finally, your market research IN AND OF ITSELF may actually help convince people to use the technology.
"It is clear that the top priority for improving the nation's highways is to focus on the quality of the roadway surface. This is the factor that will most significantly increase public satisfaction with the highway system"
– National Highway User Survey (May, 1996)
Here's an example of how we used the actual market research to convince people of the need for a technology: In 1997, we wanted to get state DOTs to use pavement smoothness incentives similar to what Arizona DOT was using. That is, if contractors on a particular paving project would get the smoothness level of their project to a certain level, the state would pay them an incentive bonus. It worked for Arizona, and we felt it would work for others. But how could we convince the other state DOTs that the public would really care about such things? Well, as it happened, in FHWA's National Highway User Survey completed a year before, one of the findings was that the public is very concerned about rough roads, potholes and the like. And this statement was included in the report summary. Notice: the top item of concern for the public was not safety or the environment…it was pavement conditions. By pointing this quote out to agency leaders and pavement staffs, we made them aware of the seriousness of the situation nationally.
More specifically, our reasons for holding this webinar are understandable when we look at what the future holds. Six years ago, SAFE-TEA-LU legislation set up the Highways for LIFE program to encourage the use of innovations. And we've been specifically pushing five innovations as what we've called Vanguard Technologies. The Every Day Counts program, begun last fall, is currently looking at about 14 different initiatives, and more may be coming in the years to come. And with the next funding authorization, we can anticipate another program, the Second Strategic Highway Research Program, or SHRP2, coming with 100 innovations. Now, I don't mean to panic anyone. This is not to say that each of these 100 SHRP2 innovations are all going to receive the same level of pushing. But it does indicate the trend toward MORE deployment, not less.
- Marketing: A Managerial Approach
by Cunningham and Cunningham
And one of the key benefits of market research is this: It can reduce decision risk by providing management with relevant, timely, and accurate information. If we realize that each innovative practice or technology we put forward is a commitment of hundreds of hours of staff time and thousands or even millions of dollars, we want our decisions to be based on accurate information, not just what we think may be the case. Too many times, organizations have pressed forward with expensive campaigns based on wrong or not thoroughly researched information, and the results have been disastrous. Examples are easy to find, both in the private and public sectors. Look at the Edsel automobile or New Coke. We really don't want to look back a year from now and say, "Oh, if only such and such hadn't happened, but we just assumed…" We all know the type of risk we take with assumptions. Good, scientifically-based market research can minimize that risk.
"The systematic gathering, recording and analyzing of data about problems related to the marketing of goods and services."
–American Marketing Association 1960
So, exactly what is market research, or marketing research? Here's the definition from the American Marketing Association in 1960…
"Marketing Research is the use of scientific data methods to identify and define marketing opportunities and problems; generate, refine, and evaluate marketing actions; monitor marketing performance; and improve our understanding of marketing as a process."
–American Marketing Association, 1991
…And here's the definition as of 30 years later, and pretty much where we are today. Basically it's a matter of trying to understand as much as possible about all the aspects that may impact how we can get our targeted audiences to use specific innovations. You might say marketing research is intelligence gathering. And just as reliable intelligence information is critical to a military campaign or to National Defense, reliable market research is critical to an implementation campaign for a technology.
Director, NuStats
But now let's go into more detail on this. Our first speaker is Mia Zmud with NuStats, and she will provide us with an overview of marketing research for highway technologies. Mia…
Scott Wolf
Center for Accelerating Innovation 202-366-1325


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Petrifaction in mythology and fiction
Petrifaction, or petrification as defined as turning people to stone, is also a common theme in folklore and mythology, as well as in some works of modern fiction.
Petrification is associated with the legends of Medusa, the basilisk, the Svartálfar and the cockatrice, among others. In fairy tales, characters who fail in a quest may be turned to stone until they are rescued by the successful hero, as in the tales such as The Giant Who Had No Heart in His Body, The Water of Life and The Dancing Water, the Singing Apple, and the Speaking Bird, as well as many troll tales.
In Cornish folklore, petrifaction stories are used to explain the origin of prehistoric megalithic monuments such as stone circles and monoliths, including The Merry Maidens stone circle, The Nine Maidens of Boskednan, the Tregeseal Dancing Stones, and The Hurlers. Supposedly petrified Cardiff Giant was one of the most famous hoaxes in United States history.
Modern fiction[edit]
|This section may contain excessive, poor, or irrelevant examples. (October 2014)
|Some of this section's listed sources may not be reliable. (October 2014)
Petrifaction magic is a major plot element in the animated series Gargoyles and the novels The Lion, the Witch and the Wardrobe, Harry Potter and the Chamber of Secrets and The Patchwork Girl of Oz (Dr. Pipt's Liquid of Petrifaction). Folkloric uses of petrification were introduced in the first edition of the Dungeons & Dragons tabletop role-playing game, which inspired later use in many video games such as King's Quest: Mask of Eternity, The Legend of Zelda: The Minish Cap, The Legend of Zelda: Phantom Hourglass, Mystery Legends: Beauty and the Beast,[1][2] and Spirits of Mystery: Song of the Phoenix.[3]
It is also featured in the novel Percy Jackson & the Olympians; the films The Snow Queen's Revenge and Willow, the manga and anime series Naruto (Senjutsu), Negima! and My-Otome; the TV series Seijuu Sentai Gingaman, Masters of the Universe (Snake Men), My Little Pony: Friendship Is Magic and Princess Gwenevere and the Jewel Riders (episode "Lady of the Lake"/"Lady of the Lake"); the video games Elite Beat Agents, Drakan: Order of the Flame, Pokémon (the move "Glare"), and The Longest Journey (Roper Klacks), among many others.
Middle-earth trolls from J. R. R. Tolkien's universe can be turned to stone by direct sunlight, as depicted in folk tales. This vulnerability is also depicted in the Norwegian film Trollhunter, a fictional documentary that contains a "scientific" explanation for this.
See also[edit]
- ^ "Mystery Legends: Beauty and the Beast Free Download Full Version". CasualGameGuides.com. Retrieved 2014-06-11.
- ^ "Mystery Legends: Beauty & The Beast Collector's Edition PC Game". YouTube. 2012-01-16. Retrieved 2014-06-11.
- ^ "SPIRITS OF MYSTERY Hidden Object 2 GAME PACK: Song of the Phoenix + The Dark Minotaur: Video Games". Amazon.com. Retrieved 2014-06-11.


text:
|Business Type:
|Manufacturer, Trading Company
|Main Products:
|Year Established:
|Total Employees:
|11 - 50 People
|Total Annual Revenue:
|US$1 Million - US$2.5 Million
Group Prospers Enterprise Co., Ltd is one of the renowned manufacturers, suppliers and exporters of Density Meters, with a factory i...
Group Prospers Enterprise Co., Ltd is one of the renowned manufacturers, suppliers and exporters of Density Meters, with a factory in Taiwan. With years of experience in the line of making, we are known for our outstanding performance in the industry. We have helped ourselves as one of the leading brand in Taiwan. We constantly upgrade our products to meet the international standards. We hold a team of professionals, which provides on time deliveries with high quality. Our sincerity and hard work has helped us match our quality with international standards.
Motto: We are always trying to create a better future for the manufactures
Group Prospers Enterprise Co., Ltd. was set up in Taiwan in 1991 by the founder, Mr. MatsuHaku-Wu.
Company has been focusing on innovation in measuring instruments and production processes, Density Meters and always tried to get familiar with the measuring methods of product density in all kinds of lines.
As the products are welcomed by worldwide customers, from the year of 2004, Group Prospers Enterprise Co., Ltd began to market to mainland China, and set the first subsidiary company XIAMEN WULING ELECTRONIC TECHNOLOGY CO., LTD. in Xiamen City, Fujian Province.
In the meantime, trade-agreements were signed with many foreign companies in countries like Sri Lanka, Burma, Spain, Japan and so on.
In the past 21 years, Group Prospers Enterprise Co., Ltd. has made huge success due to the three basic principles as follows:
- Innovative design and production.
- Worldwide network (Branches and Agencies).
- High level of competitive strength and quality.
Right Now, Group Prospers Enterprise Co., Ltd has became the professional supplier of electronic densimeters.
Group Prospers Enterprise Co., Ltd will continue to research, develop high-tech and high quality testing products for serving different industries.
Our sincerity and hard work have helped us to match the quality of our Density Meters with international standards. According to the different kinds of manufacture demands, we offer perfect services to you.
Company Capability
Trade Capacity
Accepted Delivery Terms : EXW
Accepted Payment Type : T/T
Production Capacity
Email to this supplier


text:
Registered 2009-05-19 by Moritz Strohm
This Project contains command line tools for the Moritz file system. The tools need libmoritzfs to work.
This project contains command line tools for the Moritz File System which are based on the libmoritzfs library.
The file system, libmoritzfs and mofs-cl are still under heavy development, do not use this file system on productive systems!
Project information
- Maintainer:
- Moritz Strohm
- Driver:
- Moritz Strohm
- Development focus:
- Programming Languages:
- Version control system:
- Bazaar
- Licences:
- GNU GPL v3
View full history Series and milestones
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mofs-cl trunk series is the current focus of development


text:
Get the latest Flash player
Date: 3 years ago
Runtime: 2:07
Views: 3,842
All Comments
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One of your best clips from my point of view. The way you touch yourself is so sensual xxxxxx


text:
See Cassie and Tom at the beach. See Cassie and Tom at the harbor. See Cassie and Tom at the park.
Two weeks after termed-out south-county Supervisor Tom Wilsontold me he'd have to be "crazy" to endorse either Cassie DeYoungor Pat Batesover the other in the race for his 5th District seat, I get in my mailbox yesterday afternoon an eight-page brochure that looks a heckuva lot like an endorsement to me.
Photos of Wilson and DeYoung at different locales, no doubt discussing weighty issues, appear on every page, along with a supportive quote by Wilson. For example: "Cathryn DeYoung has worked to keep (the 5th District) fabulous with her personal interest in our south county quality of life." True, neither the word "endorse" nor any variation appears, but the impact will be the same.
I couldn't reach DeYoung or Wilson late yesterday, but campaign manager Bill Kogermancharacterized the piece thusly: "Without using the word 'endorse,' (Wilson) has expressed his warm feelings for Cathryn. ... We were delighted."
My column Wednesday on DeYoung's campaign brought out a defender in former La Palma Mayor Lauree Aragona, who thinks I was a little too harsh.
Aragona says she served with DeYoung on a regional transportation committee, "and I felt she was the bravest about speaking out about the airport."
Pat Bates, Aragona says, "is a nice lady, but she should not be thought of as the heir apparent. ... I think (DeYoung) has met a lot of opposition from the established Republican inner circle."
For the record, my column focused on DeYoung's negative mail. I've not criticized her positions on issues, her bucking the establishment, spending $2 million of her own money, or anything else.
Rumor & observation
My recollection of the 1982 Ron Packardwrite-in campaign brought an e-mail from his longtime aide and consultant, Mike Eggers, who has done some political work this spring for Packard's son, Scott. A contractor and a former Vista councilman, he is running for the Assembly in a north San Diego County district that overlaps much of his father's old congressional district. He faces two other Republicans and is taking some hits on issues surrounding the loss of his Nevada contractor's license. Despite that, the San Diego Union-Tribune's Logan Jenkinsnotes that Packard "is the Cadillac of political names" and the son can't be counted out.
I see theTimes and Daily Pilot finally reported that scores of beachfront homeowners in Newport Beach must remove the lawns, gardens, etc., from the public's sand. My ego won't allow me to miss a chance to gently chide my competitors for not reporting whatprompted this flurry of government efficiency, whodiscovered the initial problem, whyhe took action or howhe documented it. At least they got the where. I guess one out of five ain't bad.
One more for Steve
If you were severely injured in an accident and realized you might be dying, wouldn't you want to think that your last thoughts and words would be about your family?
But is that reality? Might you instead focus on figuring out how to get out of the mess you were in? How soon help was going to arrive? On relieving your pain?
As it turns out, Steve Ambriztook the last few precious moments of his life to tell a cop how much he loved his wife, Bridget, and daughter, Kaitlyn, and to ask the cop to tell them so. The officer said he would, and he did.
I asked Steve's close friend and fellow Orange Councilman Jon Dumitru, who also was told of the last words, if he thought sharing them with readers was too personal, and this is what he said:
"I think that printing it would show that his love of them was till his very last moment. And maybe your readers will take that extra second out of their days to hold their loved ones and let them know they are loved. I know that for me, it was very warm to know this info and at the same time painful. But in the end, great to hear."
A scholarshipfund has been set up for Kaitlyn. Go to www.kaitlynfund.org.
Contact the writer: Mickadeit's opinions appear Monday through Friday. Contact him at 714-796-4994 or email@example.com.


text:
Eastern Africa Social Science Research Review
Volume 29, Number 1, January 2013
pp. 1-30 | 10.1353/eas.2013.0004
This study examines determinants of children's primary school enrolment. Using the 2005 Ethiopian Demographic and Health Survey data, a Binary Logistic Regression model was fitted to identify the correlates. The findings indicate that the increase in the number of siblings decreases the likelihood of children's enrolment in early ages but increases at later ages. Poverty, loss of mother, and rural residence reduce the likelihood of enrolment whilst those living in female-headed households and born to educated parents have higher chances. The findings generally entail the importance of improving households' socioeconomic wellbeing to widen the opportunity of children's school enrolment.
You must be logged in through an institution that subscribes to this journal or book to access the full text.
If you continue to experience trouble, please contact technical support.
If you continue to experience trouble, please contact technical support.


text:
Notice to UMB Cardholders � Click here if you recently received a replacement card as a result of a potential compromise.
Call us at 888.860.5862 for immediate assistance. From within the Kansas City area, call 816.860.5862. Press "0" to be transferred to a customer service representative if you have questions or problems using the automated system.
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text:
Tons of Tomes
We get lots and lots of books — bins and bins of them, even — every day. Some are suitable for our show. Some just aren't. And some could work. At our afternoon meetings, we argue doggedly for what we like. Producers pitch persuasively, but it's a hard game. Sarah's favorite probably isn't Scott's, which ordinarily isn't Barrie's. Unlike the rest of us, Neal has a "get-out-of-pitch-free" card. If he comes across a book he likes, we usually do the book. On today's show, David Cordingly, the author of one such text, Cochrane: The Real Master and Commander, will join us, to talk about Thomas Cochrane, a frigate captain during the Napoleonic Wars. He was the inspiration for C.S. Forester's famous swashbuckler, Horatio Hornblower. Fans of maritime history, we want to hear from you. What do you want to know about the 10th Earl of Dundonald?
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I'm a _huge_ fan of Patrick O'Brian's Aubrey-Maturin books, which were partially based on the exploits of Lord Cochrane. I've read the entire 20-book series once already and am contemplating another go at it. I'd be curious to hear his thoughts on how well O'Brian captured the essence of Lord Cochrane in his portrayal of Lucky Jack Aubrey.
All right, David... I know you're new to the blog, but "Windows Vista: The Missing Manual"??? Gimme some credit, man! (besides, I can't afford the Vista upgrade)


text:
Top Definition
Plural to the recently defined jumanji kid. Children who are very loud and keep people awake.
Hey you jumangi kids, you kids are grey Jews who can not be in the non-Jewish land.
by amazing javascript programmer September 10, 2008
Type your email address below to get our free Urban Word of the Day every morning!
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Free $20 e-gift card* | See the details
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Belting out the hits.
Top-grain bridle leather
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Antiqued, silver-finish buckle
Quality, comfort, and full-grain leather. Carhartt belts are strong enough to hold up your tough Carhartt pants, and a bale of hay.
Style #A94
Men's, Leather Belt


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Free weekly email packed with travel tips for major world cities, great competitions and exciting features.
This Japanese restaurant on via Ostiense is well placed for visitors to the collection of antique statues in the adjacent Centrale Montemartini. Though the...
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iHerb Customer Reviews
Items 1-5 of 5 total
It's delicous
4 people found the following review helpful
Posted by alvinlky on Apr 04, 2014
This biscuit is very delicious and best with a cup of coffee.
Posted by Reviewer2790799 on Oct 04, 2011
Fudgy and wonderful! The cream tastes like chocolate frosting!
very, very good!
Posted by Reviewer2988396 on Nov 21, 2012
very good! It`s very similar to original.
Kinnikinnick KinniToos Creme Cookies
Posted by Reviewer2144919 on Jul 02, 2013
Love it, with tea or coffee.
Delicious cookies
Posted by 4693199487931426563 on Feb 26, 2014
These are really delicious cookies, especially for someone who suddenly had to stop consuming gluten. I was a real sandwich-cookie-junky and had not had any for a couple of years till I found these. Joy and tasty! They are a little brittle and crumbly but the variety is good and a worthy purchase. The price was also competitive and bearable. This was a good purchase and well worth it.
Items 1-5 of 5 total


text:
Run Like Hell! YETI EDITION
by: Mass Creation | 8.6K
by: Mass Creation | 8.6K
Expert's review
by Manu Galvez, Appszoom
After leaving alive an island full of cannibals, our beloved archaeologist has come to Himalayas searching for an ancient artifact. However, what he has found down in the frozen caves is a huge and scaring creature that could be the Yeti. Help the guy to escape from that creature alive and he'll be able to explain the world what he saw.
Gameplay is like Run Like Hell! island edition: Jump, crawl and run even faster thanks to adrenaline boosters using a screenpad. If you fall down, get up as faster as possible or the Yeti will reach you.
There are three game modes: Endless, Avalanche and Timetrials. The only catch is that you'll have to unlock levels with in-game money (coins) and this will make you replay the same level once and again to collect the needed amount to unlock the next level. In this version you can launch thunderbolts to slow your hunter down.
Graphics are simple and cute. Screenpad controls are quite intuitive. Likewise, there's a tutorial to learn how it works. You can share your scores on online leaderboards provided by OpenFeint, as well as your achievements and challenges.
A great gameplay with an hilarious plot, graphically attractive and addictive as hell. Highly recommended.
Tags: run like hell wallpaper , foxys ride reviews , run like hell\! yeti edition , run_like_hell_5 скачать бесплатно для андроид , yeti , run from yeti , run like hell\! yeti edition taringa , run like hell yeti , como recibir el codigo de un yeti
by Manu , Appszoom
Jan 16, 2013
from 8.619 reviews
Free - V1.5.5 - 19M
Download the APK file to your computer. Once transfered to your mobile device, tap on it to install the app
Download APK
APK file Run Like Hell! YETI EDITION


text:
(Lexington KY Kentucky)
The VW Trike project for sale has a Harley front end and has an older style shifter already hooked up, left side and comes with stubby IRS axles, wire wheels with adapters.
This is a project three wheeled bike that is a nice start for the right guy with the know-how and the tools.
It has a reverse transmission in it so the trike's engine sets underneath you instead of behind you.
Go here to see more
. The trike for sale is priced to sell FAST...all it needs is a motor.
The location of the GoGoCycles Used Motorcycles for Sale and for taking a look at my VW Trike Project is Wallingford, Ky near Lexington KY Kentucky and in my opinion my asking price for this setup is cheap enough that it will be hard to beat on Craigslist or on Ebay; only $950 OR you are welcome to submit a best offer bid when you call me.
If you want to take a look or have questions about what's left to do for the project to be complete email me using the comments form.
Comments for VW Trike Project
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Join in and write your own page! It's easy to do. How? Simply click here to return to VW TRIKES CLASSIFIED AD INVITATION.


text:
- SenegalRetailFunding via CAURIE Microfinance, a partner of Catholic Relief Services
Fatou's GroupSenegalRetailFunding via CAURIE Microfinance, a partner of Catholic Relief Services
Tania's GroupSenegalRetailFunding via CAURIE Microfinance, a partner of Catholic Relief Services
Amy's Group
The group leader, Khady, is a 54-year-old married mother of eight children - four sons and four daughters. She is standing all the way on the left in the photo, dressed in a large stippled green boubou with her hand raised.
She has run a business selling various items for a long time, and has good experience in this field.
Her new loan of 55,000 FCFA will allow her to buy pairs of shoes and incense, which she will resell at retail in her area.
The profits realized from this business allow her not only to take care of her children's nutritional and educational needs, but also to strengthen her savings at the local village loan fund.
Le responsable madame khady est une femme mariée âgée de 54 ans et mère de de huit enfants dont 4 garçons et 4 filles. Elle est debout à l'extrême gauche de la photo la main levée habillée d'un grand boubou vert pointillé.
Elle s'active dans le commerce de produits divers depuis longtemps elle dispose d'une bonne expérience.
Son nouveau crédit de 55000 francs cfa lui permettra de payer des paires de chaussures et de l'encens qu'elle va revendre au détails au niveau de son quartier.
Les bénéfices réalisés lui permettent de prendre en charge les besoins alimentaires et scolaires de ses enfants mais également de de renforcer ses épargnes au niveau du banc villageois.
Additional Information
About CAURIE Micro FinanceThe mission of CAURIE Micro Finance is to contribute sustainably and to offer microfinance services adapted to impoverished micro-entrepreneurs, primarily women, based on the principles of 'credit for the poor' and on microfinance best practices, all while investing in order to become financially independent.
This is a Group Loan
In a group loan, each member of the group receives an individual loan but is part of a larger group of individuals. The group is there to provide support to the members and to provide a system of peer pressure, but groups may or may not be formally bound by a group guarantee. In cases where there is a group guarantee, members of the group are responsible for paying back the loans of their fellow group members in the case of delinquency or default.
Kiva's Field Partners typically feature one borrower from a group. The loan description, sector, and other attributes for a group loan profile are determined by the featured borrower's loan. The other members of the group are not required to use their loans for the same purpose.
About Senegal
22View loans »
Success!! The loan was 100% repaid
- Repayment Term
- 7 months (Additional Information)
- Repayment Schedule
- At end of term
- Disbursed:
- Feb 22, 2013
- Listed
- Feb 1, 2013
- Currency Exchange Loss:
- Possible
- Ended:
- Aug 17, 2013


text:
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Publications (44)126.11 Total impact
Article: Ovarian cancer G protein-coupled receptor 1-dependent and -independent vascular actions to acidic pH in human aortic smooth muscle cells[Show abstract] [Hide abstract]
ABSTRACT: Atherosclerosis is a chronic inflammation disease characterized by acidic micromilieu and the accumulation of numerous bioactive lipid mediators, such as lysophosphatidic acid (LPA) and prostaglandins, in the atherosclerotic lesion. Chronic acidification induced various effects on vascular smooth muscle cells, but the molecular mechanisms underlying these effects remain unknown. In this study, we examine the role of proton-sensing ovarian cancer G protein-coupled receptor 1 (OGR1) in extracellular acidification-induced regulation of cyclooxygenase (COX)-2 induction, PGI(2) production, MAPK phosphatase (MKP)-1 expression, and plasminogen activator inhibitor (PAI)-1 expression and proliferation in human aortic smooth muscle cells (AoSMCs). Experiments with knockdown with small interfering RNA specific to OGR1 and specific inhibitors for G proteins showed that acidification-induced COX-2 expression, PGI(2) production, and MKP-1 expression, but not PAI-1 expression and inhibition of proliferation, were dependent on OGR1 and mainly mediated by G(q/11) protein. LPA remarkably enhanced, through the LPA(1) receptor/G(i) protein, the OGR1-mediated vascular actions to acidic pH. In conclusion, acidic pH-induced vascular actions of AoSMCs can be dissected to OGR1-dependent and -independent pathways: COX-2 expression, PGI(2) production, and MKP-1 expression are mediated by OGR1, but PAI-1 expression and inhibition of proliferation are not. LPA, which is usually thought to be a proatherogenic lipid mediator, may exert antiatherogenic actions under acidic micromilieu through cross-talk between LPA(1)/G(i) protein and OGR1/G(q/11) protein.
Article: Enhanced Bioavailability of Probucol Following the Administration of Solid Dispersion Systems of Probucol–Polyvinylpyrrolidone in Rabbits[Show abstract] [Hide abstract]
ABSTRACT: Disks of probucol and solid dispersion systems of probucol-polyvinylpyrrolidone (PVP) in various weight ratios were prepared. Dissolution of probucol was markedly increased in the solid dispersion systems in J.P. XV disintegration media No. 1 (pH 1.2) and No. 2 (pH 6.8). The concentrations of probucol after the dissolution of the disks of solid dispersion systems showed supersaturation. Following the administration of disks of solid dispersion systems in rabbits, a marked increase in the area under the plasma concentration time curve (AUC) was observed. When the weight ratio of PVP to probucol was larger, a larger AUC was observed. When disks of the 1 : 9 solid dispersion system (weight ratio of probucol : PVP=1 : 9) containing 50 and 100 mg probucol were respectively administered, AUC values were approximately proportional to the dose. AUC values following the administration of disks of the 1 : 9 solid dispersion systems containing 15 mg probucol (total weight: 150 mg) and 500 mg probucol were approximately equal. The mean half life (t(1/2)) was 12 h when disks of the 1 : 9 solid dispersion system were administered, whereas the t(1/2) was 35 h when probucol disks were administered. The markedly increased dissolution of probucol in solid dispersion systems resulted in a marked increase in its bioavailability.
Article: Stimulatory Role of Lysophosphatidic Acid in Cyclooxygenase-2 Induction by Synovial Fluid of Patients with Rheumatoid Arthritis in Fibroblast-Like Synovial Cells[Show abstract] [Hide abstract]
ABSTRACT: While inflammatory cytokines are well-recognized critical factors for the induction of cyclooxygenase-2 (COX-2) in activated fibroblast-like synovial cells, the roles of biologically active components other than inflammatory cytokines in synovial fluid remain unknown. Herein, we assessed the role of lysophosphatidic acid (LPA), a pleiotropic lipid mediator, in COX-2 induction using synovial fluid of patients with rheumatoid arthritis (RA) in fibroblast-like RA synovial cells. Synovial fluid from RA patients stimulated COX-2 induction, which was associated with prostaglandin E(2) production, in RA synovial cells. The synovial fluid-induced actions were inhibited by G(i/o) protein inhibitor pertussis toxin and LPA receptor antagonist 3-(4-[4-([1-(2-chlorophenyl)ethoxy]carbonyl amino)-3-methyl-5-isoxazolyl] benzylsulfanyl) propanoic acid (Ki16425). In fact, LPA alone significantly induced COX-2 expression and enhanced IL-1alpha- or IL-1beta-induced enzyme expression in a manner sensitive to pertussis toxin and Ki16425. RA synovial cells abundantly expressed LPA(1) receptor compared with other LPA receptor subtypes. Moreover, synovial fluid contains a significant amount of LPA, an LPA-synthesizing enzyme autotaxin, and its substrate lysophosphatidylcholine. In conclusion, LPA existing in synovial fluid plays a critical role in COX-2 induction in collaboration with inflammatory cytokines in RA synovial cells. Ki16425-sensitive LPA receptors may be therapeutic targets for RA.
Article: Cyclooxygenase-2 Expression and Prostaglandin E2 Production in Response to Acidic pH Through OGR1 in a Human Osteoblastic Cell Line[Show abstract] [Hide abstract]
ABSTRACT: Acidosis has been shown to induce depletion of bone calcium from the body. This calcium release process is thought to be partially cell mediated. In an organ culture of bone, acidic pH has been shown to induce cyclooxygenase-2 (COX-2) induction and prostaglandin E(2) (PGE(2)) production, resulting in stimulation of bone calcium release. However, the molecular mechanisms whereby osteoblasts sense acidic circumstances and thereby induce COX-2 induction and PGE(2) production remain unknown. In this study, we used a human osteoblastic cell line (NHOst) to characterize cellular activities, including inositol phosphate production, intracellular Ca(2+) concentration ([Ca(2+)](i)), PGE(2) production, and COX-2 mRNA and protein expression, in response to extracellular acidification. Small interfering RNA (siRNA) specific to the OGR1 receptor and specific inhibitors for intracellular signaling pathways were used to characterize acidification-induced cellular activities. We found that extracellular acidic pH induced a transient increase in [Ca(2+)](i) and inositol phosphate production in the cells. Acidification also induced COX-2 induction, resulting in PGE(2) production. These proton-induced actions were markedly inhibited by siRNA targeted for the OGR1 receptor and the inhibitors for G(q/11) protein, phospholipase C, and protein kinase C. We conclude that the OGR1/G(q/11)/phospholipase C/protein kinase C pathway regulates osteoblastic COX-2 induction and subsequent PGE(2) production in response to acidic circumstances.
Article: Characterization of Hyaluronan-Binding Proteins on Guinea Pig Polymorphonuclear Leukocytes: Possible Involvement of Complement Receptor Type 3 (CR3, CD11b/CD18) in the Hyaluronan-Leukocyte Interaction[Show abstract] [Hide abstract]
ABSTRACT: Hyaluronan (HA), a high-molecular-weight glycosaminoglycan ubiquitously present in the extracellular matrices (ECMs) of animals, plays important roles in ECM organization and cell behavior through binding to hyaluronan-binding proteins (HABPs). We previously reported that HA has anti-inflammatory effects on guinea pig phagocytes, although the nature of guinea pig HABPs was unknown. In this study, we characterized guinea pig HABPs on peritoneal polymorphonuclear leukocytes (PMNs) and blood neutrophils by flow cytometry and affinity chromatography. It was found that PMNs express diverse HABPs with different molecular weights. These HABPs maximally bound with HA over a wide pH range (6–8), and recognized HAs as small as the pentadisaccharide units of d-glucuronic acid and N-acetyl-d-glucosamine. Furthermore, they could be divided into Mg2+-dependent and Ca2+/Mg2+-independent groups. Interestingly, two proteins in the Mg2+-dependent group were found to be the two subunits of complement receptor type 3 (CR3, CD11b/CD18). Unlike PMNs, blood neutrophils expressed several functionally inactive HABPs. Among these inactive HABPs, Mg2+-dependent proteins including CR3 but not Ca2+/Mg2+-independent proteins were activated on phorbol ester-stimulation. These results show the existence of diverse HABPs on guinea pig neutrophils and the cell activation–dependent activation of HABPs. It is also suggested that the CR3-HA interaction is possibly involved in the regulation of neutrophil function.
Article: Sphingosine 1-Phosphate Receptors Mediate the Lipid-Induced cAMP Accumulation through Cyclooxygenase-2/Prostaglandin I2 Pathway in Human Coronary Artery Smooth Muscle Cells[Show abstract] [Hide abstract]
ABSTRACT: Sphingosine 1-phosphate (S1P) has been shown to exert a variety of biological responses through extracellular specific receptors or intracellular mechanisms. In the present study, we characterized a signaling pathway of S1P-induced cAMP accumulation in human coronary artery smooth muscle cells (CASMCs). S1P induced biphasic cAMP accumulation composed of a short-term and transient response (a peak at 2.5 min) and a late and sustained response ( approximately 4-6 h). The late phase of cAMP accumulation was parallel to the increment of cyclooxygenase-2 protein expression and was inhibited by N-[2-(cyclohexyloxyl)-4-nitrophenyl]-methane sulfonamide (NS398), a cyclooxygenase-2-specific inhibitor. We were surprised to find that the cyclooxygenase-2 inhibitor also inhibited short-term cAMP accumulation even when cyclooxygenase-2 protein expression was not yet increased. More interestingly, the short-term cAMP accumulation was also completely inhibited by pertussis toxin, an inhibitor of G(i/o) proteins. JTE-013, a specific antagonist for S1P(2) receptors, inhibited the S1P-induced cAMP accumulation. Furthermore, small interfering RNAs targeted for S1P(2) receptors significantly inhibited the S1P-induced cAMP accumulation. The cAMP response was also inhibited by specific inhibitors for phospholipase C, extracellular signal-regulated kinase pathways, and cytosolic phospholipase A(2). S1P actually activated these enzyme activities and stimulated prostaglandin I(2) (PGI(2)) synthesis. Finally, exogenously applied arachidonic acid and PGI(2) induced cAMP accumulation to a similar extent as S1P. In conclusion, S1P induced cAMP accumulation through S1P receptors, including S1P(2) receptor and G(i/o) protein-mediated stimulation of intracellular signaling pathways involving cyclooxygenase-2-dependent PGI(2) synthesis.
Article: Identification of autotaxin as a neurite retraction-inducing factor of PC12 cells in cerebrospinal fluid and its possible sources[Show abstract] [Hide abstract]
ABSTRACT: Abstract Cerebrospinal fluid (CSF) induced neurite retraction of differentiated PC12 cells; the action was observed in 15 min (a rapid response) and the activity further increased until 6 h (a long-acting response) during exposure of CSF to the cells. The CSF action was sensitive to monoglyceride lipase and diminished by homologous desensitization with lysophosphatidic acid (LPA) and by pretreatment with an LPA receptor antagonist Ki16425. Although fresh CSF contains LPA to some extent, the LPA content in the medium was increased during culture of PC12 cells with CSF. The rapid response was mimicked by exogenous LPA, and a long-acting response was duplicated by a recombinant autotaxin, lysophospholipase D (lyso-PLD). Although the lyso-PLD substrate lysophosphatidylcholine (LPC) was not detected in CSF, lyso-PLD activity and an approximately 120-kDa autotaxin protein were detected in CSF. On the other hand, LPC but not lyso-PLD activity was detected in the conditioned medium of a PC12 cell culture without CSF. Among neural cells examined, leptomeningeal cells expressed the highest lyso-PLD activity and autotaxin protein. These results suggest that leptomeningeal cells may work as one of the sources for autotaxin, which may play a critical role in LPA production and thereby regulate axonal and neurite morphological change.
Article: Inhibitory effect of mizoribine on matrix metalloproteinase-1 production in synovial fibroblasts and THP-1 macrophages[Show abstract] [Hide abstract]
ABSTRACT: To investigate the mechanism of antirheumatic action of mizoribine (MZR), we examined the expression of matrix metalloproteinase-1 (MMP-1) and MMP-3 utilizing THP-1 derived macrophage-like cells (THP-1 macrophages) and human synovial fibroblasts (SFs). The cells were respectively stimulated with lipopolysaccharide (LPS) and interleukin-1beta in the presence or absence of MZR in vitro. The concentrations of MMP-1 and MMP-3 in the supernatant were measured by enzyme-linked immunosorbent assay. The secretion of MMP-1 from SFs, as well as THP-1 macrophages, was inhibited by MZR in a dose-dependent manner. Furthermore, a quantitative real-time polymerase chain reaction revealed that MZR decreased the expression of MMP-1 messenger RNA. These findings may be an explanation for the clinical effect of MZR in patients with rheumatoid arthritis.
Article: Lysophosphatidic Acid (LPA) in Malignant Ascites Stimulates Motility of Human Pancreatic Cancer Cells through LPA1[Show abstract] [Hide abstract]
ABSTRACT: Cytokines and growth factors in malignant ascites are thought to modulate a variety of cellular activities of cancer cells and normal host cells. The motility of cancer cells is an especially important activity for invasion and metastasis. Here, we examined the components in ascites, which are responsible for cell motility, from patients and cancer cell-injected mice. Ascites remarkably stimulated the migration of pancreatic cancer cells. This response was inhibited or abolished by pertussis toxin, monoglyceride lipase, an enzyme hydrolyzing lysophosphatidic acid (LPA), and Ki16425 and VPC12249, antagonists for LPA receptors (LPA1 and LPA3), but not by an LPA3-selective antagonist. These agents also inhibited the response to LPA but not to the epidermal growth factor. In malignant ascites, LPA is present at a high level, which can explain the migration activity, and the fractionation study of ascites by lipid extraction and subsequent thin-layer chromatography indicated LPA as an active component. A significant level of LPA1 receptor mRNA is expressed in pancreatic cancer cells with high migration activity to ascites but not in cells with low migration activity. Small interfering RNA against LPA1 receptors specifically inhibited the receptor mRNA expression and abolished the migration response to ascites. These results suggest that LPA is a critical component of ascites for the motility of pancreatic cancer cells and LPA1 receptors may mediate this activity. LPA receptor antagonists including Ki16425 are potential therapeutic drugs against the migration and invasion of cancer cells.
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ABSTRACT: Lysophosphatidic acid (LPA) exerts a variety of biological responses through specific receptors: three subtypes of the EDG-family receptors, LPA1, LPA2, and LPA3 (formerly known as EDG-2, EDG-4, and EDG-7, respectively), and LPA4/GPR23, structurally distinct from the EDG-family receptors, have so far been identified. In the present study, we characterized the action mechanisms of 3-(4-[4-([1-(2-chlorophenyl)ethoxy]carbonyl amino)-3-methyl-5-isoxazolyl] benzylsulfanyl) propanoic acid (Ki16425) on the EDG-family LPA receptors. Ki16425 inhibited several responses specific to LPA, depending on the cell types, without any appreciable effect on the responses to other related lipid receptor agonists, including sphingosine 1-phosphate. With the cells overexpressing LPA1, LPA2, or LPA3, we examined the selectivity and mode of inhibition by Ki16425 against the LPA-induced actions and compared them with those of dioctyl glycerol pyrophosphate (DGPP 8:0), a recently identified antagonist for LPA receptors. Ki16425 inhibited the LPA-induced response in the decreasing order of LPA1 >/= LPA3 > LPA2, whereas DGPP 8:0 preferentially inhibited the LPA3-induced actions. Ki16425 inhibited LPA-induced guanosine 5'-O-(3-thio)triphosphate binding as well as LPA receptor binding to membrane fractions with a same pharmacological specificity as in intact cells. The difference in the inhibition profile of Ki16425 and DGPP 8:0 was exploited for the evaluation of receptor subtypes involved in responses to LPA in A431 cells. Finally, Ki16425 also inhibited LPA-induced long-term responses, including DNA synthesis and cell migration. In conclusion, Ki16425 selectively inhibits LPA receptor-mediated actions, especially through LPA1 and LPA3; therefore, it may be useful in evaluating the role of LPA and its receptor subtypes involved in biological actions.
Article: Downregulation of mRNA Expression of Edg-3, a Putative Sphingosine 1-Phosphate Receptor Coupled to Ca2+Signaling, during Differentiation of HL-60 Leukemia Cells[Show abstract] [Hide abstract]
ABSTRACT: We measured the mRNA expression of the recently identified putative sphingosine 1-phosphate (S1P) receptors, i.e., Edg-1, AGR16/H218, and Edg-3, in HL-60 leukemia cells. Of these putative receptors, Edg-3 mRNA was abundantly expressed in undifferentiated HL-60 cells. Further, its mRNA expression was markedly downregulated by inducers of cell differentiation such as dibutyryl cAMP, retinoic acid, and 1alpha, 25-dihydroxyvitamin D3. The reduction of mRNA expression was associated with the attenuation of an S1P-induced increase in cytoplasmic free Ca2+ concentration. Thus, Edg-3, whose mRNA expression is downregulated during cell differentiation, may be responsible for the S1P-induced Ca2+ response in HL-60 leukemia cells.
Article: Okajima, F. et al. Stimulatory and inhibitory actions of lysophosphatidylcholine, depending on its fatty acid residue, on the phospholipase C/Ca2+ system in HL-60 leukaemia cells. Biochem. J. 336, 491-500[Show abstract] [Hide abstract]
ABSTRACT: We examined the mechanism of action of lysophosphatidylcholine (LPC), which is suggested to be involved in the pathogenesis of atherosclerosis and inflammatory disorders, in HL-60 leukaemia cells. Extracellular 1-palmitoyl LPC increased the intracellular Ca2+ concentration in association with production of inositol phosphate. These actions of LPC were markedly inhibited by treatment of the cells with pertussis toxin and U73122, a phospholipase C inhibitor. The lipid-induced stimulation of the phospholipase C/Ca2+ system was also attenuated in the dibutyryl cAMP-induced differentiated (neutrophil-like) cells, in which phospholipase C activation induced by NaF or formyl-Met-Leu-Phe was enhanced. In contrast with the stimulatory action of 1-palmitoyl LPC, 1-stearoyl LPC was inhibitory for the phospholipase C/Ca2+ system stimulated by NaF as well as by 1-palmitoyl LPC or other Ca2+-mobilizing agonists. In a cell-free system, only an inhibitory effect on phospholipase C activity was observed even by 1-palmitoyl LPC; 1-stearoyl LPC was more inhibitive than 1-palmitoyl LPC. Taken together, these results suggest that atherogenic and inflammatory LPC exerts both stimulatory and inhibitory actions on the phospholipase C/Ca2+ system depending on the species of fatty acid residue of the lipid; the stimulatory effect is possibly mediated through G-protein-coupled receptors; the inhibitory effect might be caused by dysfunction of the components involved in the enzyme system owing to the amphiphilic nature of the lipid. 1-Palmitoyl LPC prefers the former receptor stimulation at least in intact cells, but 1-stearoyl LPC preferentially exerts the latter inhibitory action.
Article: Adhesiveness for extracellular matrices and lysosomal enzyme release from normal and beta 2 integrin-deficient bovine neutrophils.[Show abstract] [Hide abstract]
ABSTRACT: The adhesiveness of control and CD18-deficient bovine neutrophils on culture plates precoated with collagen I, collagen IV, fibronectin and laminin was measured to evaluate the possible factors for adherence to extracellular matrices. The release of N-acetyl-beta-D-glucosaminidase (NAGase) from control and CD18-deficient neutrophils stimulated with complement receptor type 3 (CR3) or Fc receptor dependent stimuli was also evaluated. The adhesive activities of CD18-deficient neutrophils to collagen I, collagen IV and fibronectin were significantly diminished (P < 0.05); however, similar adhesion to laminin was observed in CD18-deficient neutrophils and control neutrophils. The adhesive activity of control neutrophils on uncoated plates increased 2.5 times (P < 0.05) with the presence of PMA. The mean activities for NAGase release from CD18-deficient neutrophils stimulated with opsonized zymosan and aggregated bovine immunoglobulin G (Agg-IgG) were 46.7 and 82.7% that of the control neutrophils, respectively. The Agg-IgG-induced NAGase release from control and CD18-deficient neutrophils was eliminated by H7, a protein kinase C inhibitor. These results support that an association between CR3 and Fc receptors on neutrophils appears to play an essential role in neutrophil functions.
Article: Biosynthesis of B2-integrin, intracellular calcium signalling and functional responses of normal and CD18-deficient bovine neutrophils[Show abstract] [Hide abstract]
ABSTRACT: 1Biosynthesis of CD11/CD18 in bovine leucocytes, intracellular Ca2+ ([Ca2+]i) signalling, chemiluminescent responses and membrane fluidity of neutrophils and the effects of D-mannose on neutrophils from control heifers and a heifer with bovine leucocyte adhesion deficiency (BLAD) were measured. The synthesis of CD11/CD18 complex was clearly detected in leucocytes from a normal heifer, but not in a BLAD-affected heifer. The transient phase of increased [Ca2+]i was clearly detected in neutrophils from a heifer with BLAD stimulated with opsonised zymosan, aggregated bovine immunoglobulin G or concanavalin A, whereas the sustained phase was deficient or significantly decreased compared with control heifers. [Ca2+]i signalling of neutrophils from control heifers and a heifer with BLAD stimulated with phorbol myristate acetate via an 11b/CD18-independent pathway showed no transient phase, and the subsequent increase in [Ca2+]i was almost identical in neutrophils from affected and control heifers. [Ca2+]i concentration and chemiluminescent responses of neutrophils from a control heifer were clearly decreased by treatment with anti-CD18 and anti-IgG antibodies. No differences in membrane fluidity were detected between neutrophils derived from control and CD18-deficient cattle. D-mannose binds mainly to Fc rather than CD18 receptors, and decreased Agg-IgG induced [Ca2+]i and the chemiluminescent response of neutrophils. The [Ca2+]i responses and Agg-IgG induced chemiluminescent responses of neutrophils from control heifers and a BLAD-affected heifer were inhibited by D-mannose. The characteristic changes of [Ca2+]i signalling and functional responses of B2-integrin-deficient neutrophils were demonstrated.
Article: Involvement of pertussis toxin-sensitive GTP-binding proteins in sphingosine 1-phosphate-induced activation of phospholipase C-Ca2+ system in HL60 leukemia cells[Show abstract] [Hide abstract]
ABSTRACT: Exogenous sphingosine 1-phosphate (S1P) induced Ca2+ mobilization, in association with an increase in inositol polyphosphate production reflecting activation of phospholipase C in HL60 leukemia cells. The increase in intracellular Ca2+ concentration ([Ca2+]i) induced by S1P was inhibited by an appropriate treatment of the cells with pertussis toxin (PTX), U73122 (a phospholipase C inhibitor) or phorbol 12-myristate 13-acetate (PMA). In parallel with the Ca2+ response, these agents also inhibited inositol polyphosphate production. The S1P-induced Ca2+ response was also attenuated in the dibutyryl cAMP-induced differentiated cells, where GTP-binding protein-induced Ca2+ response suggested to be enhanced. Lysophosphatidic acid (LPA) also increased [Ca2+]i in the cels, but the maximal response was about half of that of S1P, and furthermore PTX and dibutyryl cAMP treatment hardly affected the LPA-induced Ca2+ mobilization. We conclude that exogenous S1P mobilizes Ca2+ through phospholipase C activation. The S1P-induced enzyme activation is at least partly mediated by PTX-sensitive GTP-binding protein-coupled receptors which may be different from LPA receptors.
Article: Enhanced expression of Fc receptors on neutrophils from calves with leukocyte adhesion deficiency.[Show abstract] [Hide abstract]
ABSTRACT: The expression of Fc receptors for immunoglobulin G(IgG) and concanavalin A (con A)-binding receptors, luminol-dependent chemiluminescent (LDCL) responses, and the effect of anti-bovine IgG on LDCL responses were evaluated in neutrophils from Holstein calves with leukocyte adhesion deficiency (BLAD). Neutrophils from affected calves showed a 2.1- to 2.5-fold increase in Fc receptor expression compared with those of control calves by flow cytometric analysis. Con A-binding activities of neutrophils from affected calves were similar to those of control calves. Neutrophils from a calf with BLAD, when stimulated with zymosan opsonized with bovine serum (OPZ), heat-aggregated bovine IgG (Agg-bovine IgG), sheep red blood cells (SRBC) sensitized with anti-SRBC antibody (SRBC-anti-SRBC Ab), or con A had LDCL responses of 36 (P < 0.05), 77, 126 and 119% of peak LDCL values of controls, respectively. The NBT-reducing value of neutrophils from a calf with BLAD when stimulated with Agg-bovine IgG after pretreatment with anti-bovine IgG was 116.5% of the values of neutrophils from control calves, but the difference was not significant. The LDCL responses of neutrophils from a control calf and a calf with BLAD stimulated with OPZ were inhibited markedly by pre-incubation with anti-bovine IgG antiserum at concentrations ranging from 1.25 to 20 or 40 micrograms/ml. Although an increase in Fc receptor expression on neutrophils from calves with BLAD was observed, the LDCL responses stimulated with SRBC-anti-SRBC Ab and NBT-reducing activity stimulated with Agg-bovine IgG after pretreatment with anti-bovine IgG did not correlate significantly with the increased Fc receptor expression. These results support that neutrophil functions mediated by the Fc receptors are associated synergistically with the presence of the complement receptor type 3 (CR3)(CD11b/CD18).
Article: Characterization of functions of neutrophils from bone marrow of cattle with leukocyte adhesion deficiency[Show abstract] [Hide abstract]
ABSTRACT: Marked differences in bone marrow cellularity were observed between cattle affected with leukocyte adhesion deficiency (LAD) and control cattle. The number of nucleated cells in bone marrow was 2.9 to 8.8 times higher in cattle affected with LAD, compared with controls. The myeloid-to-erythroid ratio of bone marrow from 3 cattle affected with LAD ranged from 2.4 to 12. Deficient CD18 expression on neutrophils isolated from bone marrow of cattle with LAD was clearly detected by flow cytometric analysis. Neutrophils from bone marrow of cattle affected with LAD appeared round and not flat, after adherence to plastic wells under agarose, whereas neutrophils from bone marrow of clinically normal cattle were firmly spread on the surface of plastic wells. In the chemotaxis under-agarose assay, many pseudopodia were detected on bone marrow neutrophils from clinically normal cattle, but were not detected on bone marrow neutrophils from cattle with LAD. Activities of chemotactic movements and phagocytosis of neutrophils isolated from bone marrow of cattle affected with LAD were documented to be severely impaired.
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ABSTRACT: Expression of CD18 on bovine neutrophils in response to stimulation by zymosan activated serum (ZAS) and phorbol myristate acetate (PMA) and the effects of monoclonal antibodies (MAB) recognizing CD18 or bovine neutrophil surface antigens (S2G8 and S5F8G10) on adherence, chemotactic responses and phagocytosis of bovine neutrophils were evaluated. CD18 expression of neutrophils was increased after ZAS and PMA treatment by 12.2 and 54.2% respectively, and were significantly (p < 0.05, p < 0.01) different from those of untreated neutrophils. CD18 expression by neutrophils from a Holstein-Friesian heifer affected with leukocyte adhesion deficiency was within negative controls when stimulated by ZAS and PMA. Adherence, chemotactic responses, and phagocytosis were significantly decreased (p < 0.01) in neutrophils continuously treated with anti-CD18 MAB (MHM 23). Adherence was also significantly decreased in anti-CD18 pretreated neutrophils. Significant (p < 0.01) differences of chemotactic responses and phagocytosis of neutrophils were found between neutrophils pretreated and continuously treated with anti-CD18 MAB (MHM 23). Monoclonal antibodies to other surface antigens did not significantly alter neutrophil adherence, chemotaxis or phagocytosis. This study demonstrated that CD18 expression on bovine neutrophils is increased significantly by stimulation with ZAS and PMA and that the adhesion molecule CD18 plays an important role in adhesion-related functions.
Article: Analysis of mononuclear cell functions in Holstein cattle with leukocyte adhesion deficiency.[Show abstract] [Hide abstract]
ABSTRACT: Lymphocyte functions in cattle affected with leukocyte adhesion deficiency (LAD, termed BLAD in cattle) were evaluated by lymphocyte markers, blastogenic response, and immunoglobulin concentrations; mononuclear phagocyte functions were assessed by chemotactic and luminol-dependent chemiluminescent (CL) responses to determine the effects of impaired expression of leukocyte CD18 on mononuclear cell functions. Deficient CD18 expression on lymphocytes and mononuclear phagocytes from cattle with BLAD was clearly detected by use of flow cytometric analysis. There were no significant differences in the population of peanut agglutinin (PNA)-positive and surface immunoglobulin-bearing blood lymphocytes from clinically normal cattle and cattle with BLAD, as determined by flow cytometric analysis. Lymphocytes from cattle with BLAD had strong mitogen-induced blastogenic responses, which were greater than those from controls. Adherence of mononuclear phagocytes from cattle with BLAD was markedly impaired, and their chemotactic responses had diminished values, compared with those of controls. Luminol-dependent CL of mononuclear phagocytes from affected cattle, stimulated by opsonized zymosan, had significantly (P < 0.01) decreased values, compared with those of controls. Concentrations of IgG were markedly increased in serum from cattle with BLAD, compared with those in controls. These results indicated that impaired expression of leukocyte CD18 has marked effects on adhering activity of mononuclear phagocytes, and significantly inhibits CL response of mononuclear phagocytes mediated by inactivated-complement 3b-dependent functions. High selective immunoglobulin concentrations indicated that lymphocytes of B-cell lineage may have normal function.
Article: Dual pertussis toxin-sensitive pathway of zymosan-induced activation in guinea pig macrophages. An anti-CR3 antibody-inhibitable stimulation of phagocytosis and -resistant stimulation of O2- production and arachidonate release[Show abstract] [Hide abstract]
ABSTRACT: Complement receptor type 3 (CR3)-mediated cellular responses in guinea pig macrophages were investigated by using zymosan and serum-opsonized zymosan (SOZ) as the multivalent ligand for CR3. The ingestion of zymosan and SOZ was accompanied by O2- generation and arachidonate release. These responses were suppressed by prior exposure of macrophages to pertussis toxin (PT). Opsonization of zymosan gave rise to more than 6-fold activation of the ingestion, whereas the magnitude of either arachidonate release or O2- generation was unchanged. The Fab' fragment of anti-Z-1, a monoclonal antibody specific for the alpha chain of guinea pig CR3, inhibited the ingestion of zymosan by 60% without affecting zymosan-induced arachidonate release and O2- generation. These data suggested that there might be at least two functionally distinct binding sites for zymosan. O2- generation and arachidonate release might be regulated through one site and phagocytosis another. Both sites should be coupled to PT-sensitive GTP binding protein.
Top Journals
Tokushima Bunri UniversityTokusima, Tokushima, Japan
Hokkaido University
Sapporo, Hokkaido, Japan
- • Department of Microbiology and Immunology
- • Faculty of Pharmaceutical Sciences
Health Sciences University of Hokkaido
Tōbetsu, Hokkaidō, Japan
- Department of Microbiology
Rakuno Gakuen University
- Department of Veterinary Medicine
Higashi Nippon International UniversityIsikari, Hokkaidō, Japan


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That is one cute demon.
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Very beautiful! Love the subtle color variations.
She's hot.
If only I could draw like this! Could you please give me a hint about anatomy? Mine is terrible, that's why I end up dissatisfied with my pictures and almost never draw anything.
Nó véi q gostosa
Awesome, hope one day I will become more talented to have an art trade with you ;v;
Shes so very pretty
Are the wings on her butt, or her arms?
Very nice! 8D
So amazing, as always :3
She's looking very good
I like her in your style, such beautiful details ^U^


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Is "Family Guy" a bad show to let your children watch?
Shay 2009/11/03 00:32:08
I have grown up watching family guy but many people say you shouldn't let your children watch it. Do you agree?
Sort By
- Angelique ~ Pfffft! ;)~ 2009/11/04 02:14:16
- +1Hmmm very interesting! In some ways the show can be very crude so I get why some people wouldn't want their children to watch it. If I had children I think I would only let them watch it at a certain age and I would make sure that they knew the difference in t.v. and reality and what not to believe. Family Guy is kind of like an "R" rated movie at times.
- Artemis 2009/11/03 15:07:40
- Very reasonable answer! Do you think it depends on the maturity level of the child or should it just be 13 period?
- Hm...I think it depends on the maturity level. If you're a really immature 13 year old then you shouldn't watch it.
- annalei 2009/11/03 14:01:00
- Lol that wouldn't be good at all
- Just MEH....Piwan 2009/11/03 13:23:50
- fueledbyjeff 2009/11/03 01:27:38
- Very true. And cursing is nothing you don't here in today's world, sadly.
- fueledb... Shay 2009/11/03 01:36:02haha, im trying to quit on saying the f-bomb
- Lol everyone has their words they must restrain from using :)
- kmay 2009/11/03 01:12:03 (edited)
- Just ME... Shay 2009/11/03 13:25:46Probably about 15. Like I said, I love it, but the subject matter is too adult for children under 12. I'm not into censorsship, either, but I DO think certain things shouldn't be seen by underage kids.
- I just think it's not necessary to entertain with low class crude humor. What's the point? Do you want to copy them? No
- Smartkid1 2009/11/03 00:55:03
- What if your child showed ability to watch something like "family guy" and still have a mind of it's own and be able to differentiate between real life and a t.v. show?
- Just ME... Smartkid1 2009/11/03 13:32:17 (edited)It really is, raunchy as hell, but just sooo funny!
- ashley 2009/11/03 00:54:19
- What things do you disagree with about the show?
- Very true. They never fully expose themselves but I do agree that they have mild nudity and they do curse throughout it.
- Okkey Poo Poo 2009/11/03 00:54:14
- Lady Suspicious 2009/11/03 00:40:30
- If you were to have children do you think you would talk to them about what is right and wrong before you let them watch the show? sorry that's probably a strange question, but it was just a random thought. Lol.
- Lady Su... Shay 2009/11/03 01:23:41No, I'd just let them watch it.
- corrinne 2009/11/03 00:39:40
- Chancy99: Plague Rat 2009/11/03 00:38:43
- life sucks 2009/11/03 00:34:48
- BitterCinderella 2009/11/03 00:33:24 (edited)
- I agree.
- m.v. 2009/11/03 00:32:47
See Votes by State
2016/02/14 14:04:41
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The Pill
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New California Law Allows Women To Obtain Birth Control Without Doctor's VisitSoon, it will be much easier for women in the Bay Area and California to obtain birth control. A new law allows women to skip the doctor and go right to the pharmacy.
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Future of Iraq
Members of the House Armed Services Committee talked about their agenda for Iraq in the 110th Congress. Topics included Afghanistan,… read more
Members of the House Armed Services Committee talked about their agenda for Iraq in the 110th Congress. Topics included Afghanistan, global terrorism, al Qaida, methods of warfare, and reconstruction of Iraq. After their presentations the congressmen responded to audience members' questions. Mr. DuBois moderated.
This event titled "The Way Forward in Iraq" was part of the Congressional Forum series. close
People in this video
- Raymond F. DuBois Jr. Senior Adviser Center for Strategic and International Studies
- John J. Hamre Member Iraqi Security Forces Indep.Assess.Cmsn.
- James "Jim" Marshall U.S. Representative [D] Georgia
- H. "James" James Saxton U.S. Representative [R] New Jersey
- Isaac "Ike" Skelton U.S. Representative [D] Missouri
- Mac Thornberry U.S. Representative [R] Texas
Hosting Organization
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Secretary Gates, General Pace, and Ms. Jonas testified about the proposed fiscal year 2008 budget for the Defense…
House Session
Members debated a non-binding resolution opposing current U.S. policy in Iraq while supporting military personnel…
House Session
House Session
The House debated a non-binding resolution (H. Res. 861) on support for operations in Iraq and efforts to combat…


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I'm trying to parse a string in a specific format and I'm really surprised to discover that I can't find a good function to do that.
The only one I found is strtotime and it doesn't fit as it guesses the date format. I really don't trust the "guess" part. Moreover my string input is in a french format (dd/mm/aaaa) which it seems that it's not well understood (it parses american formats like mm/dd/aaaa).
What I'm looking for is a function that take in input a date string and a format to parse. I could do it myself with a regexp but I can't believe that it doesn't already exist.
I found :
- DateTime::createFromFormat(). But it only work with PHP 5.3 and I don't have the power to upgrade the PHP version (5.2)
- strptime(). This method does what I want but is not implemented on windows platform (by the way: WTF ??)
Any suggestion ?


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1UP Club
The New Battlestar Galactica
THis is a club for fans of the New Battlestar Galactica, if you are a fan af the old one you are welecome because the original Galactica deserves respect and credit for being the insperation for the New Series. And Sci-fi has just anounced that a spin-off series based on Galactica is in the works. It is a prequal set some 50 years befor GAlactica and it will be following the lives of two famailes on Caprica, the Greystones and the Adamas. The Adamas being the familey of William and Lee Adama of the GAlactica. The Show will be called Caprica and should come out some time next year


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The Boston Red Sox donated $10,000 to the Maine Cancer Foundation at Sunday's game at Fenway Park.
Tri For A Cure organizers reflect on what was a record year for the event that raises money for the Maine Cancer Foundation.
Sunday's Tri For A Cure, which benefits the Maine Cancer Foundation, broke records for money raised, and for organizers, there is no time to rest.
The eighth annual Tri For A Cure has raised more than $1.5 million for the Maine Cancer Foundation.
The Maine Cancer Foundation has announced a new campaign to reduce cancer in Maine by 20 percent by 2020.
Cookie Kalloch, 79, of South Portland, was this year's oldest participant of the Tri for a Cure. She gave a simple tip to others her age about longevity.
Check out photos from the 8th annual Tri For A Cure.
Meteorologist Mallory Brooke is a dedicated volunteer for the American Cancer Society, and a very personal connection is inspiring her to take part in this year's Tri For A Cure.
Watch the opening ceremony from the 8th annual Tri For A Cure.
Two storms will bring snow to Maine Monday into Tuesday.
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The Prime Minister of Israel spoke to a joint session of the US Congress. Referencing the Cuban missile crisis, Netanyahu explained that we averted disaster by deterrence. He went on to say "Now we see the rise of a similar threat. Similar and in many ways more dangerous. Against which deterrence by itself may not be sufficient. Deterrence must now be reinforced by prevention. Immediate and effective prevention." I guess he was advocating a military response to the nuclear threat. Just like he did before the Iraq invasion of 2003. However, he spoke these words in a speech to the joint session of Congress in 1996. 1996.
Thoughts On Torture
The recent revelations came as no surprise. Now we know with certainty that the United States tortured people. What are the repercussions? The Senate Team spent five years researching and putting the CIA torture report together. Apparently, it is quite thorough. What now?
Knowing this puts us in quite a bind. We can't simply say (or at least we shouldn't say), as Obama did a few years ago, that we need to look forward, not back. The flaws in this thinking are apparent, as all crimes necessarily happen in the past. With this logic, the defense of a bank robber or rapist would be very simple: "hey, that was last week. Why are you bringing it up now?"
The whole idea of cutting SNAP (Food Stamps) may well be the most heartless and mean-spirited proposal our Congress has ever made. It is literally taking food from the mouths of our most vulnerable citizens. This includes millions of children. All at a time of high unemployment and a growing wealth disparity. I don't know if we can stop these cuts but I certainly would like the Congress to know what we think about it. Perhaps, if there is enough push back members of Congress will need to factor in their next reelection bid. Please sign this petition from Daily Kos:
Can We Save Our Democracy?
Is a country with true universal single payer health care, free higher education, a concerted effort to reverse the climate crisis, and reasonable choices at the ballot box a possibility? Drs. Jill Stein and Margaret Flowers are convinced that this world can be transformed into a world of social, economic, and ecological justice. They are sure enough to have given up their respective medical practices to work full time on the changes that would lead us to this better world.
I am usually a skeptic, fluxuating between despair, anger, and a sense of hopelessnes. That being said, I have found what I believe to be a possible path out of the current mess in what these two women are saying. I plan to follow up on their suggestions, you should too.
What Advice Could Kissinger Offer
It is difficult to trust the judgement or the veracity of what the Secretary of State John Kerry says. If it weren't bad enough that his talking points don't explain the real reasons he wants to drop missiles in Syria, the point is further made by the fact that he found it useful or proper to consult with the accused war criminal, Henry Kissinger.
Based on his history, we can get a sense of what Kissinger's position is on Syria. At least we can discern what doesn't motivate him, which may be enough. He is not moved by a sense of compassion or a humanitarian interest in protecting the innocent people of Syria.
Syria: The Most Logical Answer is Usually Right
I have said and continue to say that the party that has the least to gain as well as the most to lose by using poison gas is Assad's Syria. Not that he would likely have any moral reservations about doing so, but very practical reasons not to. With Syria's well equipped military, Assad has the momentum. The only thing that could shift that momentum is intervention by outside forces. The clearly stated position of the US (the dreaded redline) makes using chemical weapons a huge risk. Doing so when the UN weapon inspectors are in Syria and only 10 miles away to boot, makes it at best moronic, at worst, suicidal.
We should ask ourselves what could he possibly hope to gain. There is no reasonable answer to this question. Assad would be exposing himself to retaliation and worldwide scorn, and no doubt he understands this. Here is a video of Acronym TV (part of The Young Turks network) detailing some of the facts. Furthermore, President Obama clearly says himself that the problems in Syria won't be solved militarily but only with a negotiated diplomatic solution. In addition, there is a well documented post by Dennis Trainor Jr. at FireDogLake.
Fool Me Once…
Let's not make the same mistake that we made in the run-up to the invasion of Iraq. I grant that Assad is an awful person. Maybe he could use nerve agents to kill his own people. But this isn't about "could," either he did or he didn't. There are some nagging questions about Syria and the chemical attacks.
Why would Assad pick the exact time that UN inspectors are already in Syria to launch a large scale chemical attack? Seriously, Assad is a bad guy to be sure but how could he run Syria for decades if he, his generals, and top advisors are all morons? This is what we are asked to believe. The regime is determined to retain power, they have the opposition forces out manned and totally outgunned. Why would he do the one thing that could instantly shift this balance of power?
Manning: A List Of Hard To Believes
It's been about a week since Chelsea Manning was sentenced to 35 years in prison. I find the whole affair hard to believe. Hard to believe that her pre-trial cruel and inhumane intentional punishment didn't play a substantial role in the process. Hard to believe that the abuse of her constitutional right to a speedy trial, despite being the longest pre-trial incarceration in US military history was ruled to not be a big deal. Hard to believe that the majority of the defense witnesses were disallowed. Hard to believe that the UN Special Rapporteur on Torture was denied a private meeting with Manning. Hard to believe that the Commander in Chief of the military by declaring her guilt 2 years before the military trial had even begun wasn't seen as influencing the outcome. Lastly, I find it hard to believe that Judge Lind was rewarded with a promotion in the middle of presiding over the case.
We stand with WikiLeaks whistle-blower US Army PFC Bradley Manning
We are American military veterans, artists, journalists, educators, homemakers, lawyers, and citizens. We live in red states and in blue states, in communities urban and rural. We ask you to consider the facts, and join us in declaring:
Enough is enough. Free Bradley Manning now.
In a time of endless war and economic distress, a cloud of government secrecy has eclipsed our republic. We are told that these secrets are necessary, that they save American lives, and we are told the growing National Security state is beyond question. More secrecy does not make us secure when it allows leaders and politicians to avoid accountability. We've learned these secrets also conceal crimes: torture, illegal surveillance, and corruption—all committed in our name. Continue reading »


text: tiny-house Gypsy Wagon Elle September 2, 2013 A refurbished gypsy caravan in Helston, UK used as a holiday rental. More info. here. ellegypse wagon 1 Comment Reply JayNine September 9, 2013 at 7:56 pm I actually love this one. Looks very sweet & soo cozy 😉 Leave a Reply Cancel Reply Name * Email * Website Previous Post The Shoebox Part 2 Next Post Minim House


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CNET brings you the best deals on tech, gadgets, appliances and lifestyle products every day. For great offers and exclusive deals on smartphones, tablets, cameras, appliances and more, find your discount here.
Fuel leak concerns prompt automaker's move. Mazda says there have been no reports of accidents or injuries related to the issue so far.
It may seem like the hype around virtual and augmented reality technologies couldn't get any bigger. But a new $800 million investment in Magic Leap shows that promise matters more than reality.
From the Cheapskate: Get ready for two extremely sweet deals on old-school analog audio gear. Plus a free year of RoboForm Everywhere!
A next-gen exoskeleton, now on sale, highlights how the latest robots are merging science fiction with reality.
Apple's smartwatch is leading to the popularity of wearable devices as a "lifestyle trend," says research firm Gartner.
Target has announced the deals it will make available on Black Friday -- Take a look.
Leaked images reveal some great deals that might be in store from Sam's Club this Black Friday.
Grand Theft Auto V, Red Dead Redemption, Mortal Kombat X, and many more see hefty discounts.
From the Cheapskate: As we round the corner into 2016, let's take a look back at some of the best deals of 2015 -- including many you can still get!
Black Friday, Cyber Monday and Green Monday are behind us. Christmas is only one week away. But there are still some great tech deals out there. (Updated December 20, 7:50 a.m. PT.)


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|It is a Louis Vuitton shoulder Saumur. In two bags back to stuck my capacity is doubled. You can enjoy the stylish fit the style of the day and as a shoulder bag, of course, through strap between the two bodies, and short, or under his arm. Open and close the belt, while Pocket one. Who have a lot of luggage bag is recommended. Available in unisex.
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"Writing reviews free shipping on" campaign only in the Sagawa express shipping within Japan. EMS shipping, international orders will be exempt.
Start Date:01/02/2016 00:00 JST
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Reflect 1 by darkmatterzoneWatch
©2012-2016 darkmatterzone
Today, ~Searine made a long overdue visit to my studio and helped me to construct a new reflector which will boost the natural light capabilities of the space. No model has ever helped out like this! Then she tested the reflector! So, not only is she exceedingly beautiful, she's rather cool, too!
Model: ~Searine
Also see: Reflect 2 Reflect 3 Reflect 4 Reflect 5
Model: ~Searine
Also see: Reflect 2 Reflect 3 Reflect 4 Reflect 5
That's awesome, way to go Searine.
Give her cookies. Wash her socks. Do whatever you need to do. Keep her around.
Thanks for sharing the story too.
Thanks for sharing the story too.
Not only she models well she also helps you set up your studio?
That IS cool.
That IS cool.
Very beautiful!


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March 17, 2008
Zack Lehatto
Nu'Keese Richardson of Pahokee (Fla.) is a name that University of Southern California fans may need to become familiar with. The 5-foot-9, 151-pound Rivals100 speedster has caught the eye of the Trojan coaching staff and the feeling is mutual with Richardson. ...More... To continue reading this article you must be a member. Sign Up Now!
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Best ID ever! XD
Lol, another one bites the dust...
And he became one with the pavement. This is too funny! Nice work!
Oh man I can't stop laughing!! Who was that kid by the way? 'cause we'd better let his parents know!!
Mwahahahahaha! Classic, need a few more cons in the gallery though Love your bots! Cute style. Reminds me of a Robot Chicken sketch, OP-"Well team we defeated Megatron again, with only 52 human casualties!"
Tis the irony behind the autobots!!! XD XD
oh, this is too much!
HA! best ID ever. XD


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Don't Miss
- COSMIC CAFE: No. 1 Sweetie
- MUSIC BOX: Bright Lights and Sounds
- GET OUT: Adventures on the Mend
- THE BUZZ: Budgeting in a Bust Cycle
- FEATURE: The Creative Conundrum
- CREATIVE PEAKS: Of Clay We are Created
- WELL, THAT HAPPENED: Trading the Hole for the Unknown
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All posts tagged "osprey"
THURSDAY 3.13 Around the world in a day Learn about different countries by traveling around Teton Literacy's classrooms to discover world cultures and cuisine. Reading Around the World: Community Literacy Event, 5 to 7 p.m. at the...
- Posted March 13, 2014


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"Springtime in Paris" Paris by TRimer
Paris Travel Guide: 23,094 reviews and 57,382 photos
Paris, the city of lights. It was as wonderful as I remembered as a child. Whether walking along the Seine or shopping in little boutiques in the Marais or on Rue Daphine in St. Germain des Pres, I was in heaven.
- Pros:Wonderful architecture, great shops, the best of France
- In a nutshell:romance and culture
Reviews (30)
Paris is a very walkable city. However, if you need to cover a lot of ground in a short amount of time- take the Metro.... more travel advice
Carries nearly 80,000 fashion labels under its roof. Along with the world's largest perfumery, the main store has the... more travel advice
The leading chain of perfume and cosmetics stores in France, sells its own makeup as well as all the big brands. Choose... more travel advice
Enjoy a drink at one of the famous cafes: Cafe de Flore, Les Deux Magots or Brasserie Lipp in St. Germain des Pres.... more travel advice
Comments (19)
Good advice on how to get along in Paris.
Traci.. loved your pics and tips for Paris. We'll be stopping there on our way to Nice in Sept. Tom
Unfortunately our experience at Il Cardinale was not good, as yours was. The pasta was either overcooked or undercooked and we were charged 25 euros ($32) per person.
You have done a very nice work on Paris here,enjoyed looking around,thanks..
Great tips, lovely pics of beautiful city. Have a wonderful BIRTHDAY .
Excellent tips on Paname (Parisian slang for Paris!)!! Nice picts too!
Traci, thanks for the lovely photos and great tips. I wish all Americans would read your tips on politeness and language!! I stole a couple of your tips for our next trip in the fall. Happy Birthday from a former Windy City Resident.
Great Paris tips, they are very helpful...hope you don't mind, but I stole a few of them! :)
Thanks for your great tips on Paris, great job!
Hi Traci. Great tips and nice photos from Par(ad)is(e). Best regards from Denmark! Brian
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Australian coach John Connolly is expecting Ireland to provide far better opposition for his side than England managed during their recent Cook Cup clashes.
The former Queensland Reds, Old Belvedere, Stade Francais, Swansea and Bath supremo said of the Irish: "They are a very stable side with Stringer, O'Gara, O'Driscoll and D'Arcy, and two world class locks (Paul O'Connell and Donncha O'Callaghan)."
Connolly's men crushed England 34-3 in last week's first Test in Sydney and repeated the trick in Melbourne on Saturday as tries from Mark Gerrard (2), George Smith, Lote Tuqiri, Mark Chisolm and Stephen Larkham saw them run out 43-18 winners over the tourists. The Australians face Ireland at the Subiaco Oval in Perth next Saturday (kick-off 11.00am Irish time).
Known in rugby circles as simply 'Knuckles', Connolly turns 55 next Monday and will be hoping his players can give him the ideal birthday present with another confidence-boosting performance ahead of their Tri Nations opener against New Zealand in Christchurch on July 8.
Looking ahead to the clash with Ireland, he added: "The Irish won't give us anywhere near the opportunities England gave us. O'Gara will control the field position. They will play a very strong field position game. They will have a good lineout, their scrum will hold up. And they really squeeze a team.
"It will be a totally different game. They don't play with anywhere near the width that England have - when you play with players on each sideline you are always going to get a very loose game.
"England play with players on each sideline. Ireland will do nothing like that. We'll have to turn up mentally to compete with Ireland. At full strength, they are a handful."
Queensland Reds prop Rodney "Rodzilla" Blake has been ruled out of next weekend's tie due to an ankle injury. Hooker Adam Freier (foot) and flanker Daniel Heenan (shoulder) are also doubtful for the 25th Test meeting between the Wallabies and Ireland.
Prop Al Baxter and Perth-based hooker Tai McIsaac are standing by to start while Brumbies star Heenan is being given "an extra couple of days" to see how the shoulder which kept him out of the second Test win over England progresses.


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After finally having been released on the Xbox 360 and PC, From Dust will be debuting for PlayStation Network on September 14th.
As with the previous versions, the game puts players in control of the God-like Breaths, which can pick up various elements of nature such as water, sand, and lava, to change the face of the land. Players will find themselves having to protect their followers from disasters such as tsunamis and volcanic eruptions.
Check out Strategy Informer's review of From Dust here.
News Story
From Dust finally hits PSN on Sept 14
08 September 2011 | By JAFalcon
- Related Games:
- From Dust
- Source:
- PlayStation EU Blog


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- 104Promote
Wall Clock
It's cold, but not grayby Bright Enough💡
Available in natural wood, black or white frames, our 10" diameter unique Wall Clocks feature a high-impact plexiglass crystal face and a backside hook for easy hanging. Choose black or white hands to match your wall clock frame and art design choice. Clock sits 1.75" deep and requires 1 AA battery (not included).
Absolutely brilliant, bold colours~ I love it!
EbiEmporium - thank you so much! I also like how the colors turned out on this one.
really like these colors. very nice :)
Thanks for your comments as well.
Thanks for your comments as well.
Fabulous piece!
nice textures
Thanks catspaws!
Awesome colors !)
Mo.Awwad - yes, I like them too - thanks you sooo much! =)
Nice work!
Thanks for the support Jena!
Nice colors in this piece.
Thanks missema!
Fabulous work
Thank you Ally! :)
Nice work!
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When a cold front moved into Somerville the middle of last week, the team at Understory sat by their computer screens, watching it engulf the city in real time. As part of a new partnership with the city, the weather tracking company is looking at Somerville as a giant lab to stress-test its novel design for a local weather monitor.
Just a year ago, Understory raised $1.9 million in funding, changed its name, and moved from Madison, Wis., to Boston to join the Bolt hardware accelerator. It is currently based at the Somerville incubator Greentown Labs, and so this project provides the company with an opportunity to tinker with its new technology in its backyard. For the city, it's a first shot at gathering high-density weather data that it can put to use during events like snowstorms.More →