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Publications (35)58.36 Total impact
Article: Evaluation of periodontitis in hospital outpatients with major depressive disorder. A focus on gingival and circulating cytokines[Show abstract] [Hide abstract]
ABSTRACT: An imbalance in stimulated cytokine production is associated with the etiopathogenesis of numerous diseases such as major depressive disorder (MDD) and periodontal disease. Increased cytokine levels have been reported in the gingival crevicular fluid (GCF) of patients with MDD. Thirty-six outpatients with MDD participated in this study. Each outpatient was age-matched (± 3 years) with a healthy control (n = 36). The patients were controlled for race and smoking habits. Unstimulated and stimulated interleukin 6 (IL-6), interleukin 1β (IL-1β), and interferon-γ (INF-γ) production in whole blood culture (WBC) and IL-6 and IL-1β levels in the GCF were evaluated. Circulating levels of IL-6 and IL-1β (unstimulated) as well as GCF IL-1β were modestly lower in MDD patients, compared to the levels in age-matched controls (Mann-Whitney, p=0.002, 0.0075, ANCOVA, p= 0.025, respectively). In the unstimulated group, there was no correlation between the levels of circulating IL-6 and GCF IL-6 (r = 0.07, p=0.67), and between the levels of circulating IL-1β and the IL-1β level in the CGF (r = -0.08, p=0.63). In the LPS stimulation group, there was no correlation between the levels of circulating levels of IL-6 and GCF IL-6 (r = 0. 02, p=0.91) or between the circulating IL-1β and GCF IL-1β (r = 0.13, p=0.42). We observed modest immunosuppression in MDD patients (evaluated by no stimulation whole blood culture [WBC]), especially in patients with melancholic depression, chronic depression, and severe depression.
Article: Scaling and Root Planning decreases the Number of Melanosomes within Keratinocytes in Human Gingiva: Ultrastructural Analysis of Three Cases[Show abstract] [Hide abstract]
ABSTRACT: The aim of the present report was to evaluate the number of melanosomes within keratinocytes on pigmented gingiva, after and before scaling and root planning. Inflamed gingiva biopsies were taken from three patients (group 1). Forty days after scaling and root planning, biopsies were collected from the homologous contralateral areas (group 2). Samples were fixed in 2% glutaraldehyde-2.5% formaldehyde (freshly prepared from paraformaldehyde) in 0.1 M sodium cacodylate buffer, pH 7.4 for 4 hours, and then processed for transmission electron microscopy. Eighty electron micrographs were evaluated for recording the number of granules by a cross-section grid. The granules that were on intersections were recorded as well as the points that appeared on the cytoplasm for calculating the volumetric density (Vd), i.e the volume that the melanosomes occupied into the cytoplasm of keratinocytes. The presence of melanosomes in different stages of maturation and distribution into the cells were recorded with the aid of a magnifying glass. For the statistical analysis, a student t-test was applied. Results of the present report showed that melanosomes within keratinocytes were present in a higher number in inflamed gingiva A (11.08 ± 1.47), B (3.16 ± 0.38) and C (4.92 ± 0.89) and decreased after resolving of gingival inflammation A (9.46 ± 0.88), B (1.73 ± 0.25) and C (0.76 ± 0.18). There is a possibility that inflammation influences the intensity of gingival melanin pigmentation. The periodontal treatment appears to have an effect on gingival melanin pigmentation.
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ABSTRACT: Background and objective: Major depressive disorder (MDD) has been associated with alterations in the neuroendocrine system and immune function and may be associated with an increased susceptibility to cardiovascular disease, cancer and autoimmune/inflammatory disease. This study was conducted to investigate the relationship between periodontitis and MDD in a convenience sample of hospital outpatients. Material and methods: The sample consisted of 72 physically healthy subjects (36 outpatients with MDD and 36 age-matched controls [± 3 years]). Patients with bipolar disorder, eating disorders and psychotic disorders were excluded. Probing pocket depth and clinical attachment level were recorded at six sites per tooth. Depression was assessed by means of Structured Clinical Interview for DSM-IV. Results: Extent of clinical attachment level and probing pocket depth were not different between controls and subjects with depression for the following thresholds: ≥ 3 mm (Mann-Whitney, p = 0.927 and 0.756); ≥ 4 mm (Mann-Whitney, p = 0.656 and 0.373); ≥ 5 mm (Mann-Whitney, p = 0.518 and 0.870);, and ≥ 6 mm (Mann-Whitney, p = 0.994 and 0.879). Depression parameters were not associated with clinical attachment level ≥ 5 mm in this sample. Smoking was associated with loss of attachment ≥ 5 mm in the multivariable logistic regression model (odds ratio = 6.99, 95% confidence interval = 2.00-24.43). Conclusions: In this sample, periodontal clinical parameters were not different between patients with MDD and control subjects. There was no association between depression and periodontitis.
Article: Clinical and Microbiologic Evaluation, by Real-Time Polymerase Chain Reaction, of Non-Surgical Treatment of Aggressive Periodontitis Associated With Amoxicillin and Metronidazole[Show abstract] [Hide abstract]
ABSTRACT: The aim of the present study is to evaluate the clinical and microbiologic changes resulting from non-surgical periodontal treatment associated with amoxicillin and metronidazole in individuals with aggressive periodontitis. Fifteen individuals with aggressive periodontitis received non-surgical periodontal treatment and 45 days after completion of treatment were treated with antibiotics. Clinical data and samples of subgingival plaque were collected at baseline, 45 days after the non-surgical periodontal treatment, and 1 month after the use of antimicrobial agents. After 3 and 6 months, only clinical data were collected. The presence and quantification of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf), Treponema denticola (Td), and Dialister pneumosintes were determined by real-time polymerase chain reaction. All clinical parameters, with the exception of clinical attachment level (CAL), had significantly (P <0.05) improved at the end of the third month after non-surgical therapy associated with antibiotics. There was significant (P <0.05) reduction in the quantities of Td and Tf. After 1 month, there were significant (P <0.05) reductions in the frequencies of Pg and Tf. Non-surgical mechanical treatment associated with the use of amoxicillin and metronidazole led to an improvement in all clinical parameters studied, except for CAL, and significantly reduced the amount of subgingival Tf and Td.
Conference Paper: Detection and Quantification of Subgingival Bacteria in Brazilian Periodontal Subjects[Show abstract] [Hide abstract]
ABSTRACT: Objectives: The aims of this cross-sectional study were to evaluate the presence and subgingival quantity of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola and Dialister pneumosintes, in individuals with Gingivitis, Chronic Periodontitis and Aggressive Periodontitis. Methods: Clinical data and subgingival plaque samples were collected from 176 individuals: 67 individuals with Gingivitis (G), 71 with Chronic Periodontitis (CP) and 38 with Aggressive Periodontitis (AP). The clinical samples were processed by real-time PCR and quantification was performed with primers and probes based on species-specifc highly conserved regions from 16S rRNA gene and serial dilutions of plasmid standards. Results: The presence of target pathogens was detected in all the periodontal disease groups and there was significant association between group and presence of bacteria for P. gingivalis, T. forsythia, T. denticola and D. pneumosintes (p<0.01). The bacterium A. actinomycetemcomitans presented similar frequencies of detection in the three groups (G: 100%; CP: 94.4%; AP: 92.1%), and there was no significant association between group and presence of this bacterium (p=0.09). The subgingival quantities of A. actinomycetemcomitans and T. forsythia were significantly higher in the Group AP (1.66*106 5.39*106 and 1.96*106 4.82*106, respectively), in comparison with Groups G (8.28*104 1.76*105 and 3.86*105 1.96*106, respectively) and CP (2.25*104 3.11*104 and 3.59*105 1.40*106, respectively), there being no significant differences among the groups with regard to the subgingival loads of the other bacteria. Conclusions: Although the presence of A. actinomycetemcomitans was similar in the three forms of periodontal disease, a higher bacterial load of this pathogen and T. forsythia was detected only in the individuals with Aggressive Periodontitis. There were no significant differences between groups G and CP regarding the quantification of target pathogens.
Article: Subgingival ultrasonic instrumentation of residual pockets irrigated with essential oils: A randomized controlled trial[Show abstract] [Hide abstract]
ABSTRACT: To evaluate the clinical efficacy of subgingival ultrasonic instrumentation irrigated with essential oils (EOs) of residual periodontal pockets. Sixty-four individuals with chronic periodontitis were invited to participate in this randomized, double-blind, parallel, and placebo-controlled clinical trial. All subjects received non-surgical periodontal therapy. After re-evaluation (baseline), residual pockets (pocket depth ≥5 mm) received test (ultrasonic instrumentation irrigated with EOs) or control therapy (ultrasonic instrumentation irrigated with negative control). Probing pocket depth (PPD), gingival recession (R), clinical attachment level (CAL), bleeding on probing (BOP), and plaque were assessed at baseline and after 4, 12, and 24 weeks. Differences between groups and changes over the course of time were analysed according to a generalized linear model. There was a significant reduction in PPD and BOP, as well as a significant CAL gain in the two groups (p<0.001). Nevertheless, there were no differences between the groups at any time of the study. When only initially deep pockets (PPD ≥7 mm) were analysed, a significantly greater CAL gain (p=0.03) and PPD reduction (p=0.01) was observed in the test group. The adjunctive use of EOs may promote significant CAL gain and PPD reduction in deep residual pockets.
Article: Presence of periodontopathic bacteria in coronary arteries from patients with chronic periodontitis[Show abstract] [Hide abstract]
ABSTRACT: In this study the presence of periodontopathic pathogens in atheromatous plaques removed from coronary arteries of patients with chronic periodontitis and periodontally healthy subjects by PCR was detected. Our results indicate a significant association between the presence of Porphyromonas gingivalis and atheromas, and the periodontal bacteria in oral biofilm may find a way to reach arteries.
Article: Clinical investigation of the efficacy of a commercial mouthrinse containing 0.05% cetylpyridinium chloride in reducing dental plaque[Show abstract] [Hide abstract]
ABSTRACT: The objective of this independent, double-blind, seven-day clinical study was to assess the efficacy of a commercially available mouthrinse containing 0.05% cetylpyridinium chloride (CPC) in preventing dental plaque build-up relative to that of a control mouthrinse without 0.05% CPC. Adult male and female subjects from the São Paulo, Brazil area reported to the clinical facility, having refrained from any oral hygiene procedures for 12 hours, and from eating, drinking, and smoking for four hours, for an assessment of the oral soft and hard tissues and a baseline dental plaque evaluation. Subjects qualifying for participation received a complete dental prophylaxis. Qualifying subjects were randomly assigned into one of the two treatment groups and were provided with their assigned mouthrinse, an adult soft-bristled toothbrush, and a commercially available fluoride toothpaste for home use. Over the seven-day period of home use, during which there were no restrictions regarding diet or smoking habits, subjects were instructed to brush their teeth for one minute twice daily (morning and evening) with the toothbrush and toothpaste supplied, to rinse their mouths with water after brushing, and then to rinse with 15 ml of their assigned mouthrinse for one minute before expectorating. The use of other oral hygiene products or procedures, such as floss or interdental stimulators, was not permitted during the study. After seven days of product use, subjects returned to the clinical facility having followed the same restrictions with respect to oral hygiene procedures, eating and drinking, as prior to the baseline examination, and the oral soft and hard tissue assessments and dental plaque evaluations were repeated. Forty-three subjects complied with the protocol and completed the study. Results demonstrated that after seven days of product use, mean plaque levels were statistically significantly lower (p < 0.05) than the pre-prophylaxis levels for both treatment groups. The mean plaque level for the CPC mouthrinse group was 46.1% of the pre-prophylaxis plaque level, whereas the mean plaque level for the control mouthrinse group was 75.5% of the pre-prophylaxis plaque level. The results demonstrate a statistically significant reduction in plaque build-up for the CPC mouthrinse group (29.3%) as compared to the control group. The overall results from this double-blind clinical study support the conclusion that, after seven days of product use, a mouthrinse containing 0.05% CPC provides significantly greater efficacy in preventing dental plaque build-up than a control mouthrinse without 0.05% CPC. As measurements were made 12 hours after final product use, the results also demonstrate that the CPC rinse provides 12-hour protection against dental plaque build-up.
Conference Paper: Incidence of tacrolimus-induced gingival overgrowth in the absence of calcium-channel-blockers[Show abstract] [Hide abstract]
ABSTRACT: OBJECTIVE: The aim of this study was to determine the incidence and severity of gingival overgrowth (GO) induced by tacrolimus (Tcr) compared with ciclosporin-A (CsA) in the absence of calcium channel blockers in renal transplant recipients. METHODS: Forty nine subjects (24 Tcr/25 CsA) were evaluated before, 30, 90 and 180 days after kidney transplantation. Demographic, periodontal parameters and GO score were recorded for all subjects. Clinical assessment was performed by a single trained and calibrated examiner (ICC=0.967) who was blinded to the patient's drug regime. GO was analyzed by visual examination of the buccal and lingual papillae of the six most anterior teeth of the upper and lower arch. A score ranging from 0 to 5 was attributed to each papilla according to the quantity of GO both in the horizontal and vertical axes. Patients showing a score ≥30 were classified as presenting clinically significant GO. Included in the study were subjects of both sexes older than 18 years, who presented no clinical or radiographic signs of periodontitis. Smokers, diabetics, patients presenting some type of gingival overgrowth during the pre-transplant period and taking any of the following drugs were excluded: nifedipine, diltiazem, verapamil, phenytoin, sodium valproate, azithromycin. RESULTS: The mean GO score was significantly lower in the Tcr group compared with the CsA group after 30 days (p=0.03), 90 days (p=0.004) and 180 days (p=0.01) of immunosuppressive therapy. At 180 days post-transplant, clinically significant GO was observed in 18% of the CsA group and in 9% of the Tcr group. This difference was not statistically significant (p=0.66). CONCLUSION: Despite of the incidence of GO in Tcr group was lower than CsA group, no significant difference in the incidence of clinically GO was observed between both groups up to 180 days of immunosuppressive therapy. (Funded by FAPESP 04/13167-1)
Conference Paper: Herpesvirus and periodontopathogens in chronic periodontitis and gingivitis brazilian patients[Show abstract] [Hide abstract]
ABSTRACT: Objectives: Herpesviruses are capable of infecting polymorphonuclear leukocytes, macrophages and lymphocytes, decreasing the host defense and allowing pathogenic bacteria overgrowth. The purpose of this case-control study was to identify and compare the presence of herpes simplex virus type I (HSV-1), Epstein-Barr virus type-I (EBV-1), human cytomegalovirus (HCMV), Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevotella intermedia, Tanerella forsythia and Dialister pneumosintes in patients with chronic periodontitis (CP group), gingivitis (G group) and healthy individuals (C group). Methods: Subgingival plaque samples were collected with paper points from 30 patients of each group. Nested PCR method was used to detect HSV-1, EBV-1 and HCMV. Bacteria were identified by 16S rRNA based PCR. Results: : HSV-1, HCMV and EBV-1 were detected in 40.0%, 50.0% and 46.7% of CP group, in 53.3%, 40.0% and 20.0% of the G group and 20.0%, 56.7% and 0.0% of C group. A.actinomycetemcomitans was identified more frequently (p<0.005) in CP group (23.3%) than in G (20%) and C group (3.3%). 73.3% of CP group and 46.7% of G and C groups were positive to P.gingivalis. P.intermedia and T.forsythia were detected respectively in 86.7% and 33.3% of CP group, 76.7% and 13.3% of G group and 43.3% and 0% of C group (p<0.005). 36.6% of CP, 16.6% and 6.6% of C group harbored D. pneumosintes (p<0.005). 2 or 3 viruses were detected in 15 patients of CP group and 9 patients of G group while in 27 patients of C group were detected 0 or 1 virus. Conclusions: HSV-1 and EBV-1 rather than HCMV are more implicated in chronic periodontitis and gingivitis in Brazilian patients. supported by grant from FAPESP 05/59292-4
Article: Detection of Herpesviruses and Periodontal Pathogens in Subgingival Plaque of Patients With Chronic Periodontitis, Generalized Aggressive Periodontitis, or Gingivitis[Show abstract] [Hide abstract]
ABSTRACT: Herpesviruses may be related to the etiology of aggressive periodontitis (AgP) and chronic periodontitis (CP) by triggering periodontal destruction or by increasing the risk for bacterial infection. This case-control study evaluated the presence of herpes simplex virus type I (HSV-1), Epstein-Barr virus type I (EBV-1), human cytomegalovirus (HCMV), Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinomycetemcomitans), Porphyromonas gingivalis, Prevotella intermedia, and Tannerella forsythia (previously T. forsythensis) in patients with generalized AgP (AgP group), CP (CP group), or gingivitis (G group) and in healthy individuals (C group). Subgingival plaque samples were collected with paper points from 30 patients in each group. The nested polymerase chain reaction (PCR) method was used to detect HSV-1, EBV-1, and HCMV. Bacteria were identified by 16S rRNA-based PCR. HSV-1, HCMV, and EBV-1 were detected in 86.7%, 46.7%, and 33.3% of the AgP group, respectively; in 40.0%, 50.0%, and 46.7% of the CP group, respectively; in 53.3%, 40.0%, and 20.0% of the G group, respectively; and in 20.0%, 56.7%, and 0.0% of the C group, respectively. A. actinomycetemcomitans was detected significantly more often in the AgP group compared to the other groups (P <0.005). P. gingivalis and T. forsythia were identified more frequently in AgP and CP groups, and AgP, CP, and G groups had higher frequencies of P. intermedia compared to the C group. In Brazilian patients, HSV-1 and EBV-1, rather than HCMV, were more frequently associated with CP and AgP.
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ABSTRACT: To evaluate the qualitative and quantitative differences on dental plaque formation on two different roughness titanium implant surfaces, i.e. machined and titanium plasma sprayed, as well as the amount of plaque removal by regular toothbrushing after 72-hour plaque accumulation. Eight systemically healthy subjects were recruited from the patient pool of a private dental practice. All patients underwent oral hygiene instruction and full mouth prophylaxis. Subsequently, maxillary casts from all patients were obtained and removable 0.7 mm-thick acetate stents without occlusal contact points were fabricated to support four titanium specimens of 4 x 2 x 2 mm divided into two groups (machined and plasma sprayed). Subjects were instructed to wear the stents for 72 hours, full time, removing them only during regular oral hygiene. Subsequently, the appliances were immediately repositioned and then the test side was brushed for 20 seconds. At the end of the 72-hour period, the stents were removed and prepared for microbiological analysis. Both machined and plasma sprayed brushed surfaces presented statistically significant fewer bacteria than non-brushed surfaces. Similarly, regarding surface roughness, machined surfaces presented a total number of bacteria significantly smaller than those presented by plasma sprayed surfaces (P < 0.05). Statistically, the non-brushed machined turned surfaces presented a greater amount of Streptoccocus sp. when compared to the brushed machined surfaces. It was concluded that rough surfaces accumulated more dental plaque than polished surfaces. Both brushed surfaces presented less plaque accumulation, however, implant brushing was more effective on machined surfaces.
Article: Herpes viruses in periodontal compromised sites: Comparison between HIV-positive and -negative patients[Show abstract] [Hide abstract]
ABSTRACT: The objective of this study was to compare the frequency of herpes simplex virus type 1 (HSV-1), Epstein-Barr virus (EBV) and human cytomegalovirus (HCMV) in subgingival plaque, saliva and peripheral blood of HIV-positive and-negative patients with periodontal disease. Fifty HIV-positive subjects (23 with gingivitis, 27 with periodontitis) and 50 healthy HIV-negative patients with chronic periodontitis were included in the study. Parameters of probing depth (PD), clinical attachment level (CAL), gingival index and plaque index were recorded. The samples were processed for viral identification by the nested polymerase chain reaction technique. HCMV was the most prevalent virus in HIV-positive (82%) and-negative patients (84%), and the detection in the three samples was similar (p>0.05). HSV-1 was the least prevalent virus in both groups, being detected in similar frequencies in oral sites and in peripheral blood. EBV-1 was found more frequently in saliva and subgingival plaque of HIV-positive patients than in HIV-negative patients (p< or =0.05). EBV-1 was more frequently recovered in oral sites of HIV-positive patients than in HIV-negative patients.
Article: Detection of Epstein-Barr virus and human cytomegalovirus in blood and oral samples: comparison of three sampling methods[Show abstract] [Hide abstract]
ABSTRACT: The purpose of this study was to identify and compare the presence of HCMV and EBV-1 in subgingival plaque, unstimulated saliva and peripheral blood of patients with chronic periodontitis. Forty patients diagnosed with chronic periodontitis (mean age, 41.7 years) were recruited. Unstimulated saliva, subgingival plaque and peripheral blood were collected from each patient and the DNA of each sample was isolated. The viruses were detected using the nested PCR technique. The detection frequency of EBV-1 in subgingival plaque, saliva and peripheral blood was 45%, 37.5% and 25%, respectively. HCMV was detected in 82.5% of subgingival plaque samples and peripheral blood and in 75% of salivary samples. The sensitivity for detecting EBV-1 in saliva and peripheral blood when EBV-1 was detected in subgingival plaque samples was low (22% and 27.7%, respectively) and the sensitivity for detecting HCMV in saliva and peripheral blood when compared to subgingival plaque was high (81.8% and 87.8%, respectively). There is a high agreement among the three sampling methods in detection of HCMV, but the detection of EBV-1 would require a combination of saliva and subgingival plaque sampling to avoid false negative results.
Article: Effectiveness of a triclosan/copolymer dentifrice on dental plaque and gingivitis in Brazilian individuais with cerebral palsy[Show abstract] [Hide abstract]
ABSTRACT: This randomized clinicai trial investigated the effect of a dentifrice containing triclosan on the reduction of dental plaque and gingivitis in institutionalized individuais with cerebral palsy. Fifty-seven residents were randomly allocated to a test group (n=28, dentifrice with triclosan) and a control group (n=29. conventional dentifrice). A single calibrated investigator performed examinations at baseline and after three months. The amount of dental plaque was assessed, and gingivitis was meas-ured. The caretakers performed brushing with dentifrice. After three months, there was a significant reduction in the plaque index in both groups, but there was no difference between the two groups. There was a significant reduction in gingivitis only in the test group, and the difference between groups was significant after three months. The authors concluded that the dentifrice with triclosan reduced interdental bleeding in the studied population.
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ABSTRACT: The aim of this randomized, controlled, single-blinded trial was to evaluate the effectiveness of a biodegradable chlorhexidine chip as an adjunctive therapy to scaling and root planing. Eleven consecutive patients with aggressive periodontitis were recruited for this study. Each volunteer provided four sites with probing depth > or = 5 mm. Two sites received scaling and root planing (SRP) and placement of the chlorhexidine chip (PC), and the other two sites received scaling and root planing only. The clinical outcomes were measured at baseline, 6 weeks and 3 months after treatment. All patients completed the trial. None of the volunteers reported any adverse effect. Both groups showed a significant reduction in periodontal pocket depth (PPD) and gain in clinical attachment level (CAL) after treatment. However, there were no significant differences in the clinical parameters between the groups after 6 weeks and after 3 months. Sites presenting probing depths > or = 8 mm at baseline treated with SRP + PC demonstrated greater reduction in PPD and a greater CAL gain than sites treated with SRP alone after 6 weeks and after 3 months. The authors concluded that the adjunctive use of the biodegradable chlorhexidine chip resulted in greater reduction of PPD and additional gain in CAL in deep pockets (PPD > or = 8 mm) in patients with aggressive periodontitis when compared to scaling and root.
Article: Expression of cell-surface heparan sulfate proteoglycans in human cyclosporin-induced gingival overgrowth[Show abstract] [Hide abstract]
ABSTRACT: Cyclosporin A-induced gingival overgrowth comprises a variety of signaling pathways (including growth factors and proteoglycans) that are still not completely understood. In the present study, gingival overgrowth was investigated in transplant patients receiving cyclosporin A (cyclosporin A group) and compared with gingival tissues never exposed to the drug (control group) by analyzing the gene expression of the cell-surface heparan sulfate proteoglycans syndecan-2, syndecan-4 and betaglycan. mRNA analysis was carried out by reverse transcription-polymerase chain reaction amplification of pooled samples from nine patients of the cyclosporin A group and six control subjects. The groups were compared by the Student's t-test. The expression of heparan sulfate proteoglycans was increased in the cyclosporin A group (165% for syndecan-2, 308% for syndecan-4, and 42% for betaglycan) compared with the control group. Our findings agree with the current concept of cyclosporin A-induced gingival overgrowth and provide new evidence that its noncollagenous extracellular matrix is overexpressed.
Article: Analysis of IL-1A(−889) and TNFA(−308) gene polymorphism in Brazilian patients with generalized aggressive periodontitis[Show abstract] [Hide abstract]
ABSTRACT: Generalized aggressive periodontitis (GAP) comprises a group of periodontal diseases characterized by the rapid destruction of periodontal tissues which affect young individuals who generally present no systemic disorders. Polymorphisms in the interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha) genes have been associated with an increased severity of chronic periodontitis. The objective of the present study was to evaluate the association between IL-1A (-889) and TNFA (-308) gene polymorphisms and GAP. One hundred nonsmoking subjects were selected, including 30 with GAP and 70 without periodontal disease. Gene polymorphisms were analyzed by the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique. For IL-1 (-889), the frequency of genotype 1/1 was 54.3% in the control group and 56.7% in the study group. The frequency of genotype 1/2 was 37.1% in the control group and 40% in the study group. Genotype 2/2 was detected at a frequency of 8.6% and 3.3% in the control and study groups, respectively. For TNFA, genotype 1/1 was present in 68.6% of control subjects and in 80.0% of patients with GAP, while the frequency of genotype 1/2 was 27.1% in the control group and 20% in the study group. Genotype 2/2 was present in 4.3% of control subjects and was not detected in the study group. The frequencies of allele 1 and allele 2 of the IL-1A (-889) gene were 72.9% and 27.1%, respectively, in the control group and 76.7% and 23.3% in the GAP group. For the TNFA (-308) gene, the frequency of allele 1 was 82.15% in the control group and 90% in the study group, whereas the frequency of allele 2 was 17.85% in the control group and 10% in the study group. Statistical analysis revealed no significant difference in allele distribution for either gene between the two groups. No association was observed between GAP and IL-1A (-889) and TNFA (-308) gene polymorphisms in Brazilian patients.
Article: Incidence of tacrolimus-induced gingival overgrowth in the absence of calcium channel blockers: A short-term study[Show abstract] [Hide abstract]
ABSTRACT: The aim of this study was to determine the incidence and severity of gingival overgrowth (GO) induced by tacrolimus (Tcr) compared with ciclosporin A (CiA) in the absence of calcium channel blockers (CCB) in renal transplant recipients. Forty patients (20 Tcr and 20 CiA) were evaluated before and 30 and 90 days after kidney transplantation. Demographic (age, gender) and periodontal parameters were recorded for all patients. Patients taking CCB at any time during the study were excluded from the investigation. The mean GO score was significantly lower (p=0.014) in the Tcr group (6.4%) compared with the CiA group (17.9%) after 90 days of immunosuppressive therapy. At 90 days post-transplant, clinically significant GO was observed in four patients of the CiA group and in two of the Tcr group. This difference was not statistically significant (0.66). No significant difference in the incidence of clinically significant GO was observed between the CiA and Tcr groups up to 90 days of immunosuppressive therapy.
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ABSTRACT: Rubinstein-Taybi syndrome (RTS) is a rare disorder affecting 1 of 300,000 people, characterized by growth, mental and motor retardation, small stature, broad thumbs and toes, characteristic face, high-arched palate, and recurrent respiratory infections. The present report describes the periodontal and immunological status of a 14-year-old female patient with RTS. Probing depth, clinical attachment level, bleeding on probing, and radiographic evaluation were performed. Periodontal examination revealed severe attachment loss in incisors and molars and generalized bleeding on probing. Periodontal treatment consisted of scaling and root planing and oral hygiene instructions. Periodontal treatment resulted in resolution of gingival inflammation and pocket depth reductions. The association of periodontal disease and RTS is previously undescribed. This case report underscores the importance of periodontal clinical diagnosis and the possibility of successful periodontal treatment in RTS patients.
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University of São Paulo
San Paulo, São Paulo, Brazil
- • Department of Stomatology (Baurú)
- • School of Dentistry (FO) (São Paulo)
- • Departamento de Estomatologia (FO) (São Paulo)


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Ferrari is a brand synonymous with Italian elegance, finesse, power, and supercar performance. With a promise to continue the family heritage, a new...
Ferrari is a brand synonymous with Italian elegance, finesse, power, and supercar performance. With a promise to continue the family heritage, a...
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View some images to go along with a Ferrari 599 GTB Fiorano review. Beyond that, there are multiple photos of the interior, exterior, engine, and more in the photo area of the Autobytel site. Fill out a price quote request form once you have completed reading Ferrari 599 GTB Fiorano reviews. It is easy to complete a quote request. Use the menu to single-out the automobile you want a quote on. Enter in an email address so you car receive the multiple quotes. Sit back and let the offers roll in. Feel free to come back and read Ferrari 599 GTB Fiorano reviews anytime day or night.

subset: commoncrawl


text:
©2010-2016 andrew77777
beautiful toes
God, I want to cum on those toes!
WOW! She really have GREAT feet, and in that shoes they look damn sexy!
Yes I do. And I wish I could suck them!
Bet those toes have been in a few mouths...
Katy perry has beautiful feet would love to take those sandals off her feet and tickle her feet and maybe suck on those gorgeous toes of hers
Très joli !
creative pedicure and nice sandals
SOoooO QT feet o_O ♥
Beautiful shoes, too. I would want a pair like that.
Cute shot~
Cute shot~


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Andrew Robb will stay on as Trade Minister for some months and hopes to finish big projects, but indicates TPP ratification won't be one of them.
The likely contender for Nationals leader Barnaby Joyce is a controversial character whose rogue approach to politics could not differ more to that of Warren Truss.
A teen girl says her two pet camels are her best friends, and she has big plans to race one in the future.
A community-backed organisation in Hay doubles its jillaroo and jackaroo trainee numbers.
Aboriginal custodians believe a massive dieback of Manna Gum in Monaro is the result of a lack of traditional burning practices.
A Riverina farmer captures what appears to be nature's version of a David and Goliath battle.
The little-known story of how sheepskin vests saved soldier's lives in WWI told in a new book.
Daniel O'Callaghan has lost weight and suffered heatstroke as he rows the River Murray.
Queensland researchers are making super-thin and durable condoms using native spinifex grass.
A central Australian trainee water well driller loves working remotely but says 'it's no ordinary job'.
A Darwin store owner is seeing the effects of the city's slowing construction industry and the toll it is taking on workers.More - ABC Darwin
Meet seven Indigenous legends taking the lead in the fields of education, heritage, climate advocacy, media and health.More - triple j Hack
An 'epic 8th Harry Potter story' will be published worldwide in July, nine years after publication of the last novel.More - ABC News
New recruits for Guide Dogs Queensland will soon begin their training journey in Brisbane.More - ABC Brisbane


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Tags: slave, doll, obey, slap, bitch, ass, scream, hardcore, sex, lesson, shove, your, rock, solid, dick, deep, inside, mouth, porn stars
Submited: 6 years old
Views: 18155
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This slave doll will obey! Slap this bitch's ass and make her scream! Give her a hardcore sex lesson and shove your rock solid dick deep inside her mouth...


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FYI - Lower Case Character sets added. I know that Garmin converts to uppercase AFAIKT, however as this OSK is part of my own FE, and I use it for Text messages on my inbuilt Phone module and for...
Liked On: 05-02-2015, 07:38 PM
its summer, good thing not that hot here! got some good news (I guess) RR is now 100% Nag/Registration free! new host for the file: OneDrive Download Here (http://1drv.ms/1stCmbM)
Liked On: 01-26-2015, 12:21 PM
Yes, in other plugin i use the Left() and not the.contains()
Liked On: 02-12-2014, 04:56 PM


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Man, this game keeps looking better and better.
» Comments: 10
g1 Discussions
Use a Facebook account to add a comment, subject to Facebook's Terms of Service and Privacy Policy. Your Facebook name, photo & other personal information you make public on Facebook will appear with your comment, and may be used on ScrewAttack's media platforms.


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A Mindful Memory Program
In Consciousness - On November 20, 2012
The 8 steps of the Mindful Memory Program is excerpted from my book Super Brain.
- Be passionate about your life and the experiences you fill it with.
- Enthusiastically learn new things
- Pay attention to the things you need to remember later. Most memory lapses are actually learning lapses.
- Actively retrieve older memories; rely less on memory crutches like lists
- Don't blame or fear occasional lapses
- Expect to keep your memory intact. Resist lower expectations from people who rationalize memory loss as "normal"
- If memory does not come immediately, don't brush it odd as lost. Be patient and take the extra seconds for the brain's retrieval system to work.
- Be wide-ranging in your mental activities, actively exercise all aspect of memory, not just the ones that come most easily.


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Solving the Top 5 Drupal Performance Issues
Join Acquia and New Relic for this upcoming webinar where we'll discuss how to use the tools provided in the Acquia Network to identify and avoid the top 5 Drupal performance issues. Darin Swanson, Senior Manager of New Relic's Agent Team will share detailed guidance on issues like N+1 Queries, Slow SQL performance, Insufficient System Resources, Web Service Domino Effect, and Repetitive World Syndrome or cache as cache can. Attendees will learn how to:
- gain visibility on site performance
- improve scalability and uptime
- find and fix key bottlenecks


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Learn how to protect yourself from Internet scams. Read our online fraud prevention tips
Business Opportunities ClassifiedsLocal NJ Classified Ads
20 listings match, 1-10 shown
Can't find what you're looking for? Try our
Advanced Search
NEW JERSEY STATE PLUMBING LICENSE AVAILABLE FOR YOUR BUSINESS. CALL 732-551-0408. Business Type: Plumbing
Web Id: 091962
Published in The Star Ledger 2/8. Updated 2/9.
Landscaping business for sale in Union county NJ. 2 trucks ,2 trailers, and 60 clients for 120K or best offer Email firstname.lastname@example.com or Call 908-447-6072
Web Id: 087222
Published in The Star Ledger 2/7. Updated 2/9.
Hair Salon/Barber Shop Available. Middlesex County shopping center. 1,300 SF - Plumbing in place. Call Jeffery Realty, Inc. 908-668-9600 Ext. 221 Business Type: Hair Salon
Web Id: 090287
Published in The Star Ledger 2/5. Updated 2/9.
ATTENTION BUSINESS OWNERS: Do you want to reach over 2 million readers? Place your 25 word Classified ad in over 130 newspapers throughout NJ for $560. Contact Peggy Arbitell 609-406-0600 ext. 14. www.njpa.org
Web Id: 088547
Published in The Hunterdon County Democrat 2/4. Updated 2/9.
ATTENTION BUSINESS OWNERS: Do you want to reach over 2 million readers? Place your 25 word Classified ad in over 130 newspapers throughout NJ for $560. Contact Peggy Arbitell 609-406-0600 ext. 14. www.njpa.org
Web Id: 87073
Published in South Jersey Times 2/4. Updated 2/4.
Job ID: STO000JQR_ Company Name: Target Job Title: Store Team Leader - Philadelphia Area Job Description: JOIN US AS A STORE TEAM LEADER Similar Industry Titles and Key Words: Store Manager, General Manager Use your skills, experience and talents to be a part of groundbreaking thinking and visionary goals. As a Store Team Leader, you'll take the lead as you... Own and champion Target-brand presentation of the entire store Manage a team of 150-500 team members Work to attain maximum profits, sales, return on investment, market share, guest goodwill and team member satisfaction Uphold the quality and productivity of every aspect of your store Direct all merchandising, operational and personnel functions Act as leader on duty responding to guest and team member concerns, as well as opening and closing the store and ensuring all Target property and personnel are secure Requirements 4-year college degree Supervisor level experience Strong cognitive skills, including problem analysis, decision making, financial and quantitative analysis Inspire and motivate your team to ensure high performing as well as Fast, Fun and Friendly store Ability to continuously move around all areas of the store on a daily basis, as well as ability to lift 40lbs Ability to work flexible hours including nights and weekends Apply URL: http://track.tmpservice.com/ApplyClick.aspx?id=2346048-2902-2074
Web Id: NJC14899711
Published on NJ.com 1/29. Updated 1/29.
COFFEE SHOP-RESTAURANT - Gross $20K/ wk, Nets $250K/yr, Ask'g $400K. GROCERY /CONV STORE - Grossing $18K/wk, Nets $175K/yr, Ask'g $400k. LAUNDROMAT - Gross $7K/wk, Nets $100K/yr, Ask'g $400K. LIQUOR STORE Essex County - Grossing $620K/yr, Nets $110K/yr., Ask'g $250K; GAS STATION Convenient Store Grossing $250,000 yr. Net $100K. Asking $220K. Bar/Restaurant- Essex County Grossing $40-$45k/wk. Net $900k. Asking 1.2 million Dry Cleaners-Essex County Grossing $150,000 per year, net $60,000, Asking $100,000 IMA Business Brokers 973-678-9400
Web Id: 083627
Published in The Star Ledger 1/29. Updated 2/4.
We have renters lined up to pay for the use of parking spaces and riveways within walking distances of train stations for $4/day. Includes:CranfordWestfieldRoselle ParkUnionSummitConvent StationMorristownMorris PlainsNew ProvidenceSouth OrangeMaplewoodMontclairRamseyAllendaleMany more
Web Id: NJC14894801
Published on NJ.com 1/28. Updated 1/28.
ATTENTION BUSINESS OWNERS: Do you want to reach over 2 million readers? Place your 25 word Classified ad in over 130 newspapers throughout NJ for $560. Contact Peggy Arbitell 609-406-0600 ext. 14. www.njpa.org
Web Id: 082763
Published in The Hunterdon County Democrat 1/28. Updated 2/3.
Classic 24 hour NJ Diner with Liquor License. Prime location on busy highway. Well established for over 3 decades serving comfort food. Huge parking lot, big full basement with private office and plenty of freezers and storage. Seats 125 people and has full bar. Nice long lease until 2031, fantastic money maker. This is a one of a kind opportunity, owner ready to retire. Serious Inquiries only please, must sign NDA. Please contact: email@example.com 732-508-4476
Web Id: NJC14889512
Published on NJ.com 1/27. Updated 1/28.
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Best Cajun Restaurant (2005)
Brooks Smokehouse Bar-B-Que
Every visit to Brooks Smokehouse is a two-for-one treat. Not only do Ronald and Louella Brooks serve some of the town's best BBQ in their odd little spot, but they also dish up fried gator, good Frenchy frogs' legs, fat boudin sausages and a stellar, tomato-heavy crawfish étouffée. The Brookses originally hail from Louisiana, the cradle of Cajun cooking; lucky for us, they didn't leave any flavor behind when they brought that fiercely regional cuisine to the Mile High City.
More Food & Drink Awards
Best New Restaurant (Since March 2004)Frasca
Best New Law"Doggie-Bag" Wine
Best Neighborhood RestaurantRosa Linda's Mexican Cafe
Best New Restaurant NeighborhoodLarimer Square


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Music Releases
[Updated] ALi returns with the release of "Eraser" mini album + MV starring Choi Ji Woo
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Talented soloist ALi has returned with the release of her mini album, 'Eraser' ('Ziugae'), and the music video for the title track of the same name!
The MV for "Eraser" previously made headlines for featuring a top Hallyu actress, who has been revealed to be Choi Ji Woo.
In addition to the title track, the album features 4 other songs and its instrumentals, one of which is her pre-release track "Selfish" (which you can check out here).
Check out the MV and the other tracks below
The Tears Are Gone (ft. Kang Jun of C-Clown)
Don't Say Another Word
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New Additions to the Database
2015 Topps Limited - 700 Cards!
2015 Bowman Chrome Draft - 123 Cards!
1994 SP Die-Cuts - 199 Cards!
Other Recent Additions
2015 Bowman - 60 Cards
2015 Bowman Chrome - 70 Cards
2015 Topps Heriatage - 59 Cards
214 NMMT Vintage Cards added to 1978 Topps, 1979 Topps, and 1980 Topps
1978 Topps - 282 Cards
1979 Topps - 345 Cards
1980 Topps - 139 Cards
2015 Topps - 103 New Cards
2015 Topps Heritage - 62 New Cards
2014 Bowman Draft - 125 New Cards
2014 Bowman Chrome Draft - 291 New Cards
Recent Articles
Biggio, Johnson, Matrtinez, and Smoltz added to the Hall of Fame
Ranking the Top 50 MLB Prospects 2015
Older Articles
Dont throw out those Baseball Cards
Toughest jobs in sports: Baseball card shop owner
10 Tips to Win at Baseball Card Investing
|What is Baseball Card Collecting?
|Baseball card collecting connects fans with baseball players and gives the fan a sense of involvement in game. Collecting baseball cards has been a popular hobby for over 100 years. A collector has quite a selection of cards from which to collect. This can be confusing but it also offers freedom. In the end the choice of what you should collect is yours. A theme or taste often guides a collector.
Some collectors collect cards from a specific era or type or of a favorite player or team. Some collectors collect unusual or rare cards. Some collectors simply collect what fancies them at the moment. Some collectors change their focus over time, perhaps switching from 1950 Topps and Bowman to 1930s Goudey. Some try to create sets gathering each different card from a particular issue. Some collect errors or variations. Some collect players from their home town or school. Some collectors specialize in rookie cards. Some collect the aptly named odd ball cards which includes cards like the Cranes Potato Chip Discs, Armour Hot Dog Coins and Spic n Span Die-Cuts.
|Recent Additions:
|Huge selection of Vintage Rookie cards have been recently added to our database!
|Baseball Card Care, How to take care of your cards.
Taking card of your cards is essential in keeping their value. An accidental ding or crease can lower a cards value. There are many affordable products to protect your cards.
|Baseball stars from the National League and the American League played the first All-Star Game in 1933. The National League has won 41 of the 80 games. The game ended in a tie twice. In 1961 rain in Boston prevented extra innings and the game ended in a 1-1 tie. And in 2002, the game went 11 innings with the score knotted at seven before it was finally called off due to a lack of pitchers.


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Placement of Embryos
After the eggs have been harvested and mixed with sperm to create embryos, they are stored in a lab until the mother (biological or surrogate) has them planted in her uterus. Doctors will implant two to four embryos at a time to increase your chance of being pregnant. Note: Multiple babies also increases the complications and health risks for them and the mother, Web MD writes.
(Photo: HANK MORGAN/GettyImages)
Cyber Monday: All Natural Moisturizers11/28/2015
HIV, AIDS and Black America: By the Numbers11/17/2015
The 411 on Hepatitis C07/24/2015
June 27 Is National HIV Testing Day06/27/2015
The Danger Behind Butt Injections06/04/2015
Major Slim Downs: Stars Who Underwent Weight Loss Surgery05/14/2015
Mother's Day Yoga With Faith Hunter05/10/2015
Nine Ways to Mentally Cope With Racial Injustice04/28/2015
Running a 5K: What You Need to Know04/24/2015
Health Rewind: 1,000 People Sent to Hospital Over Fake Weed04/21/2015
Speaking Out: The Health Causes That Celebs Support04/20/2015
Medical Racism: What You Need to Know04/16/2015
Health Rewind: Darren Sharper May Have His Penis Monitored04/13/2015
Did Johns Hopkins Infect Study Participants With STDs?04/10/2015
Lessons From the Red Carpet: How Celebs Stay Healthy04/10/2015
The 411 on Young People and HIV/AIDS04/10/2015
The Todd Family: When Carbon Monoxide Kills04/08/2015
That Ain't True: 8 Myths About Autism04/07/2015
That Ain't True! Debunking 8 STD Myths04/03/2015
Processed Foods and What You Need to Know04/01/2015
Health Rewind: Is Evolution Behind Why We Like Big Butts?03/24/2015
Obamacare Turns Five03/23/2015
Health Rewind: Do #BlackLivesMatter in the Doctor's Office?03/19/2015
The 411 on HIV/AIDS and Black Women03/10/2015
What Black Women Living With HIV Want You to Know About AIDS03/10/2015
What You Need To Know About Kidney Health03/09/2015
Health Rewind: Dating Violence Affects 1 in 4 Girls03/06/2015
Remembering Islan Nettles03/05/2015
Dating Diaries: 10 Signs of a Healthy Relationship02/26/2015
Health Rewind: PrEP Found to Reduce HIV Transmission02/25/2015
Teen Dating Violence: What You Need to Know02/23/2015
Okla. Bill Could Make Engaged Couples Get Tested for STDs02/20/2015
The 411 on Surviving the Extreme Cold02/18/2015
Health Rewind: Is it Hard For Blacks to Talk About Sex?02/13/2015
The 411 on Blacks and Heart Health02/12/2015
The 411 on Measles02/06/2015


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Kailashahar Hotels
3 Kailashahar Hotels List ranked by travellers
Average Rating - 5.00/7, based on 21 Ratings & 12 Reviews | Price Range : Rs. 200 - 600
Rank 1
Kailashahar, Gor Nagar, North Tripurar
"I want to share my best experience with you that I have with my family. I went on a holiday trip..." More ›Ayush, Noida, 3 months ago
Rank 2
Old Motor Stand, Netaji Corner, Kailashahar
"We stayed in Agartala. Its about 2 and half days in this hotel. goodl furniture and communicated..." More ›Raj, Hyderabad, 3 months ago
Rank 3
Near Kadalgidi Park, Kailashahar, North Tripura
"Stayed here for around 5 Days and I was personally a lot Impressed by them. Their Outstanding..." More ›Abhishek, Allahabad, Sep 6, 2015
Hotels in Kailashahar with Tariff Rates
- There are 3 hotels in Kailashahar reviewed by actual travellers. The top rated Kailashahar hotels are Circuit House, Unakoti Tourist Lodge, Nirmala Hotel. The lowest available tariff for Kailashahar hotels stands at Rs.200 and highest hotels rate is approximately Rs.600. You can search for Kailashahar B&B/Guest house/Hostel/Lodge(2), Kailashahar Hotel
There are different types of hotels in Kailashahar available for families, lovers, kids, friends and specially for newly married couples who are looking for perfect honeymoon destination.
Hotels in Kailashahar by PriceThere are 3 Budget hotels in Kailashahar which are priced below Rs. 2500. Tariff for hotels in Kailashahar starts from 200. Cheap hotels in Kailashahar may provide basic amenities like a private bedroom, colour TV, Telephone, AC, 24-hour front desk and housekeeping staff on call. These hotels are affordable and value for money.
Hotels near Main Attractions in KailashaharThe most popular attractions in Kailashahar are Unakoti, Chouddo Devotar Mandir, Lakhi Narayan Bari, Tea Estates and you can find 2 hotels near Unakoti, 2 hotels near Chouddo Devotar Mandir, 2 hotels near Lakhi Narayan Bari, 2 hotels near Tea Estates.
Hotels near Main Transportation PlacesThere are 1 railway station in Kailashahar which is Guwahati railway station. You can find 56 hotels near Guwahati railway station.


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Music blog
Lyrics/song texts are property and copyright of their owners and provided for educational purposes only.
Love Is All Around Lyrics
Love Is All Around Song Lyrics
I feel it in my fingers, I feel it in my toes
Love is all around me and so the feeling grows
It's written on the wind, it's everywhere I go, oh yes it is
So if you really love me, come on and let it show
You know I love you, I always will
My mind's made up by the way that I feel
There's no beginning, there'll be no end
'Cause on my love you can depend
I see your face before me as I lay on my bed
I kinda get to thinking of all the things you said, oh yes I did
You gave your promise to me and I gave mine to you
I need someone beside me in everything I do, oh yes I do
You know I love you, I always will
My mind's made up by the way that I feel
There's no beginning, there'll be no end
'Cause on my love you can depend
Got to keep it moving
Oh it's written in the wind, oh everywhere I go, yeah, oh well
So if you really love me, love me, love me
Come on and let it show
Come on and let it show, come on and let it
Come on and let it (come and let it show, baby)
Come on, come on, come on let it show baby
Come on and let it show, come on and let it show, baby
Come on and let it show
By bit (bit by bit, bit by bit)...
Classic Love at the Movies Song List
›My Heart Will Go On
from Titanic / Celine Dion
›I Will Always Love You
from The Bodyguard / Whitney Houston
›We Have All The Time In The World
from On Her Majesty's Secret Service / Louis Armstrong
›Up Where We Belong
from An Officer and a Gentleman / Joe Cocker and Jennifer Warnes
›As Time Goes By
from Casablanca / Frank Sinatra
›Take My Breath Away
from Top Gun / Berlin
›Can You Feel The Love Tonight
from The Kion King / Lion King Cast
from A Star is Born / Barbra Streisand
›Love Is All Around
from Four Weddings and a Funeral / Wet Wet Wet
›Try A Little Tenderness
from The Commitments / The Commitments
›Gabriel's Oboe (Instrumental)
from The Mission / Ennio Morricone
›Nuovo Cinema Paradiso (Instrumental)
from Cinema Paradiso / Ennio Morricone
›Adagio from Piano Concerto No. 2 (Instrumental)
from Brief Encounters / Rachmaninov
›Intermezzo from Cavalleria Rusticana(Mascagni) (Instrumental)
from The Godfather III / Pietro Mascagni
›Maid Marian At The Waterfall (Instrumental)
from Robin Hood, Prince of Thieves / Michael Kamen
›Princess Leia (Instrumental)
from Star Wars / John Williams
›For The Love Of A Princess (Instrumental)
from Braveheart / James Horner
›Love Theme (Instrumental)
from Out of Africa / John Barry
›Love Theme (Instrumental)
from Romeo and Juliet / Peter Tchaikovsky


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Open Source Graphics Card for Developers
The Open Graphics project has released specifications for its first card and will accept orders at a price of US$ 1500.
If the price sounds reasonable to you, what you get in the OGD1 FPGA Development Kit is a PCI X reference card, the PDF format manual on a CD and a DVI-VGA adapter. According to the orders page one hundred orders are required to manufacture the card. To make things easier, the first one hundred customers will be given a US$ 100 discount on their orders with a Lattice programming cable added into the bargain.
The board with its completely open specification has the following parameters: PCI/PCI-X (33/64-bit, 33-133MHz), 256 MByte DDR400 graphics memory, Lattice LFXP10 non-volatile FPGA (specification sheet), Xilinx Spartan-III XC3S4000 FPGA (specification sheet, Silicon Image SiI178 Dual Link DVI Transmitters, Philips TDA8777 Triple 330Mhz 10-bit Video DAC, Conexant CX25874 Video Encoder, dimensions: 6.875 x 4.2 inches, power consumption: ~20 watts.
Linux drivers are not currently available for the PCI card as the reference card is mainly targeted at developers.
Issue 184/2016
Buy this issue as a PDF
Linux Foundation Eliminates Individual Membership
But you can still be a non-voting "individual supporter" if you pay the money
Secret Backdoor Affects More Fortinet Firewalls
Several current systems could fall victim to the attack
Linus Announces Linux Kernel 4.4
Latest Linux engine comes with better graphics and support for Intel's new power-saving chips.
Mass Poem Greets Web Admins
Hackers send a message of beauty and liberation to server logs
Raspberry Pi Becomes a Thin Client
Citrix gets excited about new Pi-Powered XenDesktop client system
Microsoft Offers Linux Certification
Linux on Azure cert heralds a new era for Redmond.
CeBIT 2016: Call for Open Source Contributions
Proposals for presentations at the CeBIT Open Source Forum will be accepted through 24 January 2016.
Gone in a Flash
Adobe looks for a new start; renames its embattled Flash tool.
Rasp Pi Generates Weak SSH Keys
The Pi's popular Raspbian OS pursues secrecy without entropy.
Photon Controller Goes Open Source
VMware bids for a stake in the container industry with a bold effort to integrate containers with its classic virtualization system.


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Re: Stupids play now
I guess it improves your odds a bit if you're properly connected...
38 posts • joined 14 Jan 2010
I guess it improves your odds a bit if you're properly connected...
Move to renewable continues at same rate
Large % of base load PV
ITER still being built with costs spiraling
New Solar Minimum
Do we need any more reasons to build good old fashion nuke plants?
PoE and pass through to power the Chromecast would be really useful. Opportunity missed....
Having flown with a HUD, KISS is the important thing. If you really need green arrows pointing the way around the car in front, you shouldn't be driving. Reserve it for over speed alerts and other *critical* information - not at all surprised about the findings of this report, tbh
Interesting replies - thought it was going to stimulate some debate; didn't expect to be down voted to oblivion though :)
Awesome engineering achievement and not knocking it, but Philae, Opportunity etc all go way beyond their design life. I understand that these things take years of planning and getting them off this rock in the first place is not cheap, but as SpaceX et al lower the launch costs, there must start to be a case to go for more, simpler, cheaper probes with a faster launch rate.
Just sayin'
Shit like this makes me proud to be British.
Shit like this also makes me sad for what we've become :(
With the big man on this - what possible use is it in 99.999% of deployments? Pretty sure it was still present in the last lot of SM boxes we rolled out and was certainly in Dells before we booted them into touch...
Good trip down nostalgia alley there, but needs to tip the hat to Trumpet Winsock, as the MS implementation was (if it's possible) worse than the associated version of IE. Best {however much it was} I ever spent.
Used to run 4x analogue lines, but had to move office. New place on a different exchange so would have to change the numbers - disaster. However, simple to port existing numbers to VoIP
Offset the money saved on lines on a biz grade connection (EFM) and gone for hosted VoIP with a load of Yealink handsets (They're cool - can do API stuff with them as well to link with CMS)
+ As many outgoings and incomings as I want, great as we grow
+ Simple, Web panel for call groups, IVR, etc etc
+ Easy to add DDIs for marketeers etc
+ Better Internet for the company as a whole (10Mb up and down, uncontended and unmetered)
+ Great DR as if we lose the office, can carry on from any internet connection.
+ Part timer/home worker carries on as if at her desk
+ No BT involvement, not even their copper
+ Actually, the last deserves many more +++s ++++++++^29
- Lose the 'net, lose everything
- EFM is chuffin pricey, but offset by not having the copper and *is* on a 6hr SLA
- Lost the fax and no easy way to plug the alarm in with an autodialer
- Outgoings are a tad more expensive, but we don't do too much of that
That's about it, tbh. We're a rural biz in a small market town; experience has been uniformly good for the last 3 years+
No advert and no connection, but our provider is Dial9 and they've been brilliant and wouldn't hesitate to recommend them.
Whilst I think this is awesome and would buy one in a shot, can't help thinking that it's not going to help the space junk situation. Maybe not this project, but one like it and soon...
..if it was Microsoft, it'd be all "You look like you're trying to launch a recoverable space craft. Do you want help with that?"
I find it really encouraging that private biz is pushing up into LEO.
That's it - nothing profound :)
You're assuming that this thing is not just a load of cameras and stuff designed to tempt the thing to get close to do the same
+1 for you, sir. (Not convinced about the long term accessibility bit, though!)
We've used OO here for ages and are very happy with it, but recently had to fork out for a fistfull of MSO licences just to read some bloody contract documentation and get the bullet numbers to order correctly.
I've no evidence to support this, but I suspect the vast majority of users don't use Macros and other fiddly bits in their day to day ops (we certainly don't) and wouldn't notice the difference.
Big Q for you, though - is this policy going to rattle down to schools and stop the problem at source?
Given my Math, that's probably a good plan :) You able to log the demanded servo deflections when in flight?
SuperTim raises a valid point - where is the Centre of Pressure on that thing? I'm assuming it was modelled to death in the design phase, but 2 things occur to me and I cba to go back through the archives to see if they were addressed:
1. The air's very thin up there. Relative airspeed will be low, so large control deflections will be required to control the vehicle. The force needed to move the control surfaces will be correspondingly reduced, so rather than gear down (as it looks at the moment), I'd consider gearing up. In a previous life, I used to fly pointy things for the Queen; my aerodynamics are a bit rusty now, but I still remember wallowing around at over 40K feet, full throttle with a stupidly high ground speed and being only a few Kts (Indicated) above the stall...
2. That shape of aerofoil is going to result in drastic shifting of the CoP if it moves far, so the pivot point needs to be biased (imo) to the high load / high deflection position.
My 2p
This makes their entire "Certified" program look very questionable - what *exactly* does that testing regime involve? I/O is one of the easier things to test, imho....
fwiw, I heartily approve of the canine naming convention. If Johnny local doesn't "Get" it, that's his loss.
"We spoke to an IT operations manager at one major NHS trust who struggled to recall being contacted by central government on the end of Windows XP."
There's a man who earns his salary....
But think of the benefits when (s)he gets all wobbly.
I like it. Bring me another!
Very well done, my dear sir.
May I propose that you give it a few hours to get around the intertubes, then change to something along the lines of
Look for another installer :) The delta between a fixed array and a tracker is around 6K istr
Anyhoo - bit of a cloudy start to the day, but note when it begins / finishes generating.
Oh, and you're assuming a catastrophic fail of the inverter, but I take your point.
A friend put up a 3.5KW PV array on a 2-axis tracker a few weeks ago (~£17K). Now I accept that it's sunny weather, but he got 42KWh out the thing the other day - that's a real-world, pukka figure. Also, remember that he isn't paying to import those KWh from the grid out of taxed income which further skews the financial argument.
The ROCs and FIT are doing their job - promoting alternative energy sources and micro-generation. I fully expect them to be reviewed / cut soon (Surprised they weren't in april, tbh) now that the ball is rolling.
It's all well and good to blame the Govt / Fat cat suppliers, but burning dino juice/gas to make electricity is madness - we need to be sharper than that. Personally, I'd like to see a crash Nuclear program in the UK but we've pi$$ed away our expertise in that field and have to make do with what we can.
Should call Mr Tuttle - he'll sort it out for them.
"both of them claim 3-3.5k watts of power usage"
Thin - apart from the 6' heatsink
Step 1 : Spend a fortune on a Web2.x thingamy
Step 2 : Realise you've blown the budget
Step 3 : Rent a low-end VPS from a kiddy host
Step 4: Splash all over the media with a launch date
Step 5 : Leave your audience looking at "Loading" icons or white pages
Step 6 : Audience go away and may come back in a few months if you're lucky
Step 7 : Pats on the back and Martinis all round
..no one can hear you scream. So why are the radiators(?) on that uber-rocket thing streamlined?
Grips my tits when spacecraft are made to look and manoeuvre like aircraft...
Yes, I live in the country.
Yes, my ADSL connection was an unstable 256Kb at best.
Yes, I now use a 3G dongle with a planar antenna and a transparent caching proxy.
Yes, my speed is still pants.
Yes, I decided to live here.
No, I'm not going to move.
It's not a "Basic human right" (whatever tf that means). When BT was GPO, you had due cause to bitch. Now? Welcome to capitalism.
I Love to count!
One! Nun! Joke! Ha ha ha
Two! Nun! Jokes! Ha ha ha
Most (all?) mobile providers run NAT - my iPhone is currently on a 10.x.x.x IP and my 3G dongle with 3 does the same. I agree we need to move to IP6, but factual inaccuracies don't help the cause. Also, there's a *lot* of public address space that's wasted:
Do IBM et al all *need* those /8s? I think not...
...they're off-the-shelf timers :)
...his penis was "severely swollen, his blood pressure was up and his heart racing"
Just saying...
Fair point - I just hope it's not too intrusive and turn-offable.
Oddly, I'm not wowed by the external lib integration - Spotify has more tracks than I'd ever manage to accumulate in a couple of lifetimes.
Two reasons I went "Premium" on Spotify:
1) I have no problem with paying for music and this was an excellent service.
2) I got fed up with interruptions from Jonathan and eSuit2.0 or whatever they were
I'm still happy with 1, but it sounds like 2 is in peril. I just want to listen to music, ffs - no one else likes the crap I listen too and I'm not particularly interested in what my friends listen to either. There's plenty of play list sites out there and, tbh, I found them too hard to use (Wheat/Chaff syndrome)
/me gets back to the Happy Mondays
"he looked at the health records out of curiosity, not to make money" - well, that's all right then, isn't it.
This is just one reason why I've opted my family out of having an SCR. Madness.
Was toying with the idea of upgrading to an HD TV and BluRay , but will now hold off until the 3D format wars sort themselves out. If the Glassesless tech can be sorted out as well, that'd be just dandy.


text:
A trans-Atlantic cast lands a rowdy Richard III in San Francisco
THEATER A single black armchair center stage and one big fat "Now" projected on the back wall signal our anticipation pretty neatly — of a famous opening line, of the famous actor about to utter it, and in the feeling that it is something more than a history play unfolding here, at this moment, in a city and country thoroughly and unprecedentedly "occupied" with political matters. A big, pungent production of Richard III? Yes, now sounds about right.Read more »
The Jewish Theatre launches its final season with a resonant new play about the Group Theatre
THEATER The company members onstage had started out just a couple of hours ago in literal harmony, joined in song. Now everyone appears spent, heated, and confused. They wonder what has happened to them. They wonder if they've lost their way; if their extraordinary effort and success over recent years has been worth anything. It's a moment of truth, fraught with personal and collective drama, overshadowed by desperate and tumultuous times. The Group Theatre, arguably the most influential theater in American history, is about to disband.Read more »
Dark Porch Theatre explores familial foreignness in Tutor
email@example.com more »
Stage: Aurora Theatre offers a terrific revival of an Albee classic
THEATER New plays are usually big selling points for theaters, and they have a certain pizzazz for audiences too, but their power to renew interest in theater is a different matter. The best play seen on a local stage so far this season is not a new play, as it happens, but an old one, with a big name attached and a Pulitzer in tow. But Edward Albee's A Delicate Balance (1966) reminds you why people go to the theater in the first place.Read more »
SF Fringe Fest turns 20
THEATER Here's a preliminary accounting from the San Francisco Fringe Festival, which remarkably turns the big two-oh this year. (There's a nifty 2012 wall calendar to mark the occasion available somewhere in the Exit Theatre complex, traditional nerve center for the lottery-based festival started by Exit stalwarts Christina Augello and Richard Livingston.)Read more »
Big Art Group's secret ingredient is revealed as The People descends on Z Space
More signs of gentrification in the Bay Area, this time sanguine, as Los Angeles-based Impro Theatre's acclaimed show, Jane Austen Unscripted, returns starting tonight (Wed/7) for gigs at 142 Throckmorton Theatre (Mill Valley) and BATS' Bayfront Theater (SF). If you saw Jane Austen Unscripted in one of its two previous local engagements over the last few years, you already know the group sports some of the quickest wits in the Western canon. Jane Austen Unscripted is directed by BATS cofounder Dan O'Connor and comedian-writer Paul Rogan and features an amazing cast of improvisers, fully capable of creating a full-length play in the style of Jane Austen spontaneously each night, with a theme suggested by the audience. Improv fans, Austen fans, ceiling fans: this stuff is hot. A funnier, sharper assemblage of off-the-cuff maestros is hard to come by, especially in cuffs like these.
Read more »
Exit, Pursued by a Bear goes all Wild Kingdom on domestic matters
THEATER A sweet, normally placid Southern working-class wifey named Nan Carter (Erin Gilley) — no relation to Jimmy, but oh how for some reason she wishes! — takes revenge on her abusive husband Kyle (Patrick Jones) with the help of two close friends, a roll of duct tape, a fresh deer carcass, and a working knowledge of the dramatic arts in Crowded Fire's world premiere of playwright Lauren Gunderson's light but witty comedy.Read more »
FALL ARTS PREVIEW: Autumn's most intriguing theatrical events
FALL ARTS Puppets, fanciful forms of democracy, and disfigured villains are leitmotifs beyond the Beltway this season, as the following theater and performance highlights suggest.Read more »
Reviving Gertrude Stein and Virgil Thomson's Four Saints in Three Acts


text:
Originally posted on BaySportsNet | Last updated 8/23/13
On a breezy evening at Banner Island Ballpark in Stockton, Oakland A's left-hander Brett Anderson took a big step towards returning to the big league rotation. "I've never really had too much success in rehab starts, but thats kind of beside the point," said Anderson. He finished his night throwing 3.1 innings and giving up five runs on five hits, including a pair of home runs. "Nobody likes to give up runs, nobody likes to lose, but it's not the priority at this point. The first priority is feeling good. My body feels good, my arm feels good, and we'll see what happens from here." On a night when the Stockton Ports, the Single-A affiliate of the A's, lost 8-1 to the San Jose Giants, Anderson struck out six and walked a pair. Anderson appeared to move just fine out on the mound, and said he was unbothered by his foot. "There was a couple of ground balls to first where I had to make a move over there, and my foot felt fine." Anderson last pitched for the A's on April 29 as he went 5.1
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October 7, 2001
Trevor Ariza to visit Duke and UNC this weekend
Top 20 junior target Trevor Ariza will be visiting the Duke campus this weekend, along with attending Midnight Madness at UNC.
Ariza is one of only a handful of targets we believe will garner serious looks from the class of 2003. (We will be releasing our list later this week). He will be watching practices and touring the campus among other activities.
He is a very sound offensive threat who had an impressive summer. He can score from all over the court including the post and perimeter.
Stay tuned for more on Ariza and other top 2003 prospects.
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text:
Lautrec doesn't need bonfires by MenasLGWatch
©2012-2016 MenasLG
Lautrec taking care of the Firekeeper.
That's why I always kill him on sight.
That's why I always kill him on sight.
of all your work. This is my favorite. So good. Would have loved to see a color version
i hate him so much
Come on guys, lautrec didnt do anything wrong, he was cool.
Well I let him kill her, so that when I bring her back she gets her tongue back and can talk to you now.
Hahah, I remember when the bonfire in Firelink Shrine was gone and I was so confused. I was also wondering why Lautrec was gone. And then I found out it was him who killed the Firekeeper. I was so pissed xD
Awesome drawing, great job
Awesome drawing, great job
can you get his armor if you kill him right a way
*a knight dressed in the armour of Artorias wielding the lance of Ornstein impales the golden knight before he can do anything*... sleep now.. your goddess waits to take your soul into her embrace
//sees bonfire is out// Dingy ropes.
"Hey Lautrec do y-" //lautrec is gone/
"Hey Lautrec do y-" //lautrec is gone/
Touching my waifus always have consequences, like being "THIS IS LORDAN"ed off the cliff EVERY playthough after that, but yeah Lautrec is a great character
Oh the things he dose for love.
but you can revive her after you fine and kill him
i usually free him, kill the bell gargoyles, get my sunlight medal , summon him with solaire against Gaping Dragon , then go back to firelink, and pushes him off the cliff .
I hate this as much as I love it.
Well, Lautrec might not need bonfires... BUT I DO!!
I felt sooo stupid for letting him live the first time playing DS, I just KNEW there something off about the way he spoke, argh why didn't I see it?! awesome interpretation as to what hapened
I hate myself because I let him kill her...
Killed this douche-nozzle and his two butt-buddies. Feels good, man.
Gz, he was more aggressive than I thought the first time I fought him.
The only reason he's annoying is because 1. His weapons ignore your shield and 2. He's got the help of his 2 buddies.
too handsome to kill.
my character, as a gravelord, is pretty much the divine retribution of lordran... for lautrec's crimes, i stabbed him in the back... for patches' crimes, i threw him to the fucking skeletons... if thee be of a wicked soul, thou shalt be punished severely...
What about Petrus?
ah, yes... the cleric... stabbed in the heart by a skillfully-timed riposte...
since posting this, muro has slain the gravelord and lost his purpose... however, through the guidance of mr. jolly cooperation himself, he has dropped the mantle of the gravelord, set aside his gravelord sword, and taken up the armor and weapons of the new londo darkwraiths to act as the champion of the warriors of sunlight... in other words
PRAISE THE SUN! \o/
PRAISE THE SUN! \o/
Cannot rest at bonfire!? goes to see fire keeper, Dingy Robes?....Thinks a little....LAAAAAUUUUUTREEEC!!
...Me too!
I tried doing a Lautrec build once, just for the hell of it.
Good lord was that a horrid idea.
Good lord was that a horrid idea.
Before you all go apeshit on Lautrec, think of all the things the chosen undead does...
He ruins pretty much everything xD
Perfect example is the chosen undead killing Kirk, Kirk was keeping the fair lady of chaos alive by invading and giving the humanity to her and the chosen undead kills him which is basically locking blight-town and all around that area in permanent shit-ness XDDD
He ruins pretty much everything xD
Perfect example is the chosen undead killing Kirk, Kirk was keeping the fair lady of chaos alive by invading and giving the humanity to her and the chosen undead kills him which is basically locking blight-town and all around that area in permanent shit-ness XDDD
Survival of the fittest, those that live decide who was good and who was bad I guess.
Embraced by his shining gold armour,
With a wicked soul and stained karma.
He craved her pure soul,
And with a smile he stole,
That poor firekeeper's life and disgraced her
With a wicked soul and stained karma.
He craved her pure soul,
And with a smile he stole,
That poor firekeeper's life and disgraced her
C'mooon, Menas. You telling me you didn't gut a pretty lady or two for a juicy Flask upgrade?
Is what I screamed at my TV when I invaded.
Is what I screamed at my TV when I invaded.
Same thing happened to me hahahaahah! I was playing with a character with a badass face and when I invaded his world , and my knight watched him , I say : ''I'M COMING , YOU MOTHERFUCKER. FOR THE FIREKEEPEEEEEEEEEEEEEEEEEERRRR'' and they kicked my ass. They I came again with more tactic and a better armor.... and I fucked Lautrec up. Satisfing.
Am I the only one here who revived her? because you can do that you know...
Honestly, in the long run there's no reason to not let him kill her. By the time the Firelink fire is out, you already have Sen's opened and should just be using the Parish bonfire. The next time you'd actually maybe need Firelink-Four Kings-isn't until after you should have been able to reclaim her soul. Plus, along with the Ring, you also then get his armor set and after offering a Lord Soul to the Lord Vessel you can speak to her and she'll kindle Firelink to 20 Estus automatically.
Dingy robes is one of my favorite light armor sets and I always feel bad getting them.
Love it, absolutely great job.
Love it, absolutely great job.


text:
Cupid's working overtime this Valentine's Day, and he's getting a little help from his friends, including George W. Bush. The president has asked Congress for more than $1 billion to promote, stabilize and strengthen marriage, especially for low-income Americans. But it's the culture that needs help.
We could probably learn a thing or two from Amelia Limpert, age 100, who was married for 82 years. Her husband died the other day at 102. They broke off their engagement three times. But one day in 1921 they jumped into George's Model T Ford and eloped. They got no help from the government - it never occurred to anyone then that the government had any business with Cupid - but society at large imposed expectations that seem quaint today.
Liberals have dismissed the president's concern for what he calls the "sanctity of marriage" as a cynical sop to the religious right, and they may be right that marriage counseling is not a legitimate function of government. But you don't have to be right, left, Republican, Democrat, born again, agnostic or atheist to recognize that the president is right that "a strong America must also value the institution of marriage."
Homosexuals are pushing to "marry" just when marriage is having a hard time. Homosexual marriage mocks the very idea of marriage as a stabilizing force for raising families. There are many exceptions, of course, but the homosexual culture in general promotes promiscuity: 'Til Death Do Us Party. This is a difficult observation to make publicly, but it's well understood in the gay community.
Heterosexuals have their swinging parties and marriages break up over adulterous liaisons, but fidelity in marriage is honored even in its breach. When Congress enacted the Defense of Marriage Act in 1996, Bill Clinton, the commander-in-cheat or not, eagerly signed it.
I've resisted supporting a constitutional amendment defining marriage as a union between a man and a woman because recognizing and regulating marriage has always been a function of state government.
But law is ever more being made in the courts, and Congress, always eager to pass the buck, goes along to get along. Soon the states will accept same-sex marriages. A gay couple, for example, could be married legally in Massachusetts, where such unions are recognized, and then go to any of the states that have no defense of heterosexual marriage and demand recognition of their marriage. The states without laws prohibiting same-sex marriage would soon be under enormous judicial pressure to go along
Suzanne Fields is currently working on a book that will revisit John Milton's 'Paradise Lost.'
Be the first to read Suzanne Fields' column. Sign up today and receive Townhall.com delivered each morning to your inbox.©Creators Syndicate
Rush Limbaugh defends Rubio's debate answer: He's absolutely right that Obama knows what he's doing | Allahpundit
Time for Team Hillary to break out the gender card for young liberal women who prefer Sanders | Allahpundit


text:
Notes & Reviews:
At first glance, there appears to be little connecting the composers Paul Juon, Fabian Mu¨ller, Ernest Bloch and Arthur Honegger save their common Swiss heritage and the fact that the works recorded here call for a string orchestra and solo instrumentalists. Slightly over nine decades separate the youngest and oldest of these composers; their biographies and oeuvres, however, reveal a number of surprising similarities. Founded in 1964 in Tbilisi, Georgia but based in Ingolstadt, Germany since 1990, the Georgisches Kammerorchester is here led by its newly minted (2015) A.D. Ruben Gazarian.


text:
Mona Vale Rd reopened at Terrey Hills after fatal car accident
- From: The Daily Telegraph
- April 09, 2014
- Fatal crash at Terrey Hills
- Four-car accident in Moore Park
- Three-car smash at Beacon Hill
- Breakdown on General Holmes Drive
A FEMALE passenger has been killed and a man remains in hospital following a car crash in Sydney's north.
The woman died at the scene when a small hatchback left the roadway on Mona Vale Rd and crashed about 4.15am.
The male driver was taken to hospital and his condition is being assessed.
It is believed the vehicle rolled before coming to rest on a grass medium strip.
Police spoke to a witness at the scene and their investigations are ongoing.
The incident affected Mona Vale Rd well into the morning. It was reopened just before 10am.
The westbound lanes of the dual carriageway were closed with one lane of traffic moving each way through the regular eastbound lanes.
A four-vehicle accident blocked one of three north-bound latnes at Anzac Pde and Alison Rd in Moore Park causing heavy delays.
There was also heavy traffic on General Holmes Drive near the M5 on-ramp at Mascot following a breakdown this morning.
One of four southbound lanes was closed and traffic was queued back to Southern Cross Drive.
A three-vehicle smash at Beacon Hill caused moderate delays at Warringah Rd and Government Rd.
Motorists travelling on Military Rd at Neutral Bay were delayed by the tidal flow system not working.
Brought to you by Live Traffic NSW | map view
####Originally published as Mona Vale Rd reopened after crash
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text:
Cut-Out Tool with 5 Amp Motor and 30,000 RPM
The DeWalt cut-out tool is extremely durable and efficient. This amazing tool features a turn-on/bump-off switch which allows user to easily shut tool off. Making these even more versatile is the tool-free bit change for fast and easy bit changing without a wrench.
- Tool-free bit change for fast and easy bit changing without a wrench
- Turn-on/Bump-off switch allows user to easily shut tool off
- 5.0 Amp, 30,000 rpm motor provides more cutting power
- Slim body design for less fatigue over prolonged use
- Dust-Sealed Switch protects against dust ingestion for longer switch life
- Jam-pot construction provides jobsite durability
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- No Load Speed: 30,000 rpm
- Collet Diameter: 1/8", 1/4"
- Adjustable Guide: Yes
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- Tool Length: 10"
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- Shipping Weight: 3.5 lbs
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text:
Kimberly A. Blanchette
- Author in Janesville, WI
- Travels up to 200 miles
- $150-$1000
- Free Quote
Why book Kimberly A. Blanchette?
Be the first to review Kimberly A. Blanchette.
Booking Info
- Fee: $150-$1000
- Languages: English
High energy, entertaining, funny, full of personality, articulate, and personable.
Additional Booking Notes
Kimberly doesn't require any special lighting or staging. Depending on the event she does like to have a podium.
Past Booked Events
|Janesville, WI
|National Womens' Music Festival
|Rockford, IL
|Rockford Pride Fest
|Janesville, WI
|Wisconsin Capitol Pride
|Outreach of Rock County
|Middleton, WI
The team providing the talent:
Colleen Frentzel
Partner, Manager, Publicist
Influences & Inspiration
Shakespeare, Mike Ditkas City Lights, many different Poets, Authors and Actors.
Setup Requirements
From a simple chair to full-blown stage and lighting, there are certain configurations and needs that many performers and service providers require in order to provide the best possible experience at your event. Get a free quote request to check with Kimberly A. Blanchette to find out what their setup requirements are.Free Quote Request
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text:
DETROIT -- Not even the site of the venerable Tiger Stadium is large enough to hold all the agents and bureaucrats it takes to tackle the workload of the FBI's ever-expanding Detroit bureau.
In the region of the nation's largest Arab-American population, hundreds of terror-related investigations are reported to be ongoing, propelling the growth of the bureau.
Although the agency's personnel numbers are not made public for security reasons, the FBI's 100,000 square feet of office space in Detroit is inadequate, said Special Agent Dawn Clenney.
"We started hiring additional employees after September 11, and now we have intelligence analysts, translators and more special agents," Agent Clenney said. "We are now one of the top 15 agencies as far as personnel, with a very substantial number of terror investigations. More so than other FBI offices because they don't have that large a [Middle Eastern] population."
The Detroit News has reported that since September 11, Detroit's FBI office more than tripled the number of agents working on counterterrorism. And of 29 major terror groups known to be working in the U.S., the Detroit office has ongoing investigations involving 17.
The FBI is seeking a 266,000-square-foot space on as much as 11 acres with a budget of $65 million. And the vacant Tiger Stadium's six-acre site -- briefly pondered -- won't work despite its massive presence in a deserted area west of downtown.
Among the requirements: a 100-foot setback from the street to discourage terrorist attacks via car bombs.
The Arab-American community here has decried the anti-terror efforts and denied that the region is a haven for terrorist funding. Still, the U.S. attorney's office in Detroit has successfully prosecuted many people in the past four years for supporting terror groups.
"I hope that the need for this expansion is not as great as they are making it out to be," said Tim Attalla, a lawyer and activist in Detroit's Middle Eastern community, estimated at 350,000 people.
Mr. Attalla grew up in that community and recalls that even in the 1970s there was a strong law-enforcement presence in it.
"Back then it was the state police," Mr. Attalla said. "And I also remember the FBI knocking on doors in the Middle Eastern community, usually early in the morning. Once it was just before Yasser Arafat [came to the U.S.]. They would ask general questions, just keeping tabs, it seemed."
Now, though, the FBI is used as a reliable threat in the community even in the case of personal conflict.
"But I do know that in our community, when there is a squabble, sometimes an angry wife or relative will call the FBI and tell them so-and-so is funneling money to Hezbollah just out of anger. So there is no shortage of informants in the Arab community here," Mr. Attalla said, in reference to a Lebanese militant group.


text:
At Norwalk Hospital, our exceptional patient care stems from world class doctors with diverse and substantial strengths in many medical specialties. The talent of our staff along with our commitment to comprehensive care makes Norwalk Hospital the "Hospital of Choice" for the community of Fairfield County, by both doctors and patients alike.
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Norwalk Hospital
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Norwalk, CT 06856
Phone: 203-852-2609
Fax: 203-852-3436
Trying to contact someone specific on our medical staff?
Looking for a physician? Use our Find a Doctor tool.


text:
|ISSN 1088-6826(online) ISSN 0002-9939(print)
A necessary and sufficient condition for a -manifold to have Heegaard genus one
Abstract | References | Similar Articles | Additional Information
Abstract: Let be a closed -manifold. R. H. Bing showed that is homeomorphic to if and only if every simple closed curve in can be isotoped to lie inside a -ball. We generalize this to show that there is a solid torus imbedded in such that every simple closed curve in can be isotoped to lie in if and only if has a genus one Heegaard splitting.
Retrieve articles in Proceedings of the American Mathematical Society with MSC: 57N10
Retrieve articles in all journals with MSC: 57N10
Additional Information


text:
Mess Perfect 2 - 075 by EpantirasWatch
©2011-2016 Epantiras
The best part is? They're the most likely Cerberus outfit to ever do this. TIM apparently put together the crew out of the most sympathetic individuals his shitty terrorist group had.
despite Cerberus' best efforts to make Shepard happy, Shepard's not happy. This scene shows why
GARDNER! The perv is coping a feel!
Lol! I see miranda in the back XD
Wait , what?
ahhahahahahahahahahahah XD I can't stop laughing!
Oh, my God, I can't stop laughing! Soooo much goodness. In Kelly's defense, Shepard's face in panel 1 really does look like he's in dire need of a hug.
I'd only imagine that joker could have died in that group hug XD.
Biancaneve in mezzo ai nani.
OMG Shep's face in Panel #3!
Whenever someone besides my girlfriend tries to interact with me: Panel 3.
Miranda doesn't look too happy...
Was that Conrad Verner running up to join the hug??!! No? No. Okay continue!
Cerberus group hug!!
This is why the Squad keeps their problems to themselves. I never want Joken breaking his arm huggin me ever again.
Oh gods I would NOT put it past her to pull something like this.
HAHAHAHAAH so awesome!
this comic gave me planty of reasons to download Mass Effect 2 again !
this comic gave me planty of reasons to download Mass Effect 2 again !
*dies from laughing*
So... random! I love this comics
that look on shepards face just before the horror started. priceless!
Gardner just got back from unclogging grunt's toilet/ fixing up dinner
take it like a boss shepard
Yeaaaaaaaaa, to bad I have to kill mostof them next game
Miranda: >
Lol. The idea of everyone in Cerberus being trained to respond to that is hilarious.
I love it how Miranda is still angry!
I love that you gave Mess Sergeant Gardner's bright rubber gloves and a pink apron.
LOL no xD
How is Joker standing??
Cerberus gave him mechanical implants to help him walk.
After that, I REALLY wanna turn them into human smoothies.
*died laughing*
Oh dear - first the Plot twist dance and now a Cerberus group hug? Another new Mass Effect meme is born.
i find it funny how i see chakwas, gardner, joker [mustve left normnady on auto-pilot, but wow - he halled ass for hugging shepard], ken and gabby etc. XD
i find it funny how i see chakwas, gardner, joker [mustve left normnady on auto-pilot, but wow - he halled ass for hugging shepard], ken and gabby etc. XD
This looks like the beginnings of a new Meme.
Joker ftw
Did I see Conrad Verner sneak into the Normandy?
Come on Shep, give Joker some love, he probably broke an ankle getting there so fast!
Use the emergency-"hug attack"-airlock Shepard!!
Not Kelly! No! She's a lot better in... not-Reaper juice form... thing. Also, you will never remember to check your email without her.
How did Joker get over there so quickly?


text:
Hands tutorial by SouOrtizWatch
©2013-2016 SouOrtiz
Well here my "first" tutorial ^^ this time of hands D:. Hope you help guys!.
Is advisable that you use references for poses if you're a beginner, on google you can find a lot, but here I post some tutorials and hands poses that you can use :3:
Another tutorials ^^:
Note: If you want a custom tutorial like this, please check my commissions list shinsoumidna.deviantart.com/jo… here ^^
•Paint tool sai
•Art•: *ShinsouMidna©
Paypal commission are open!
Check out the prices list shinsoumidna.deviantart.com/jo…
Thanks you everyone ^^~
You can follow me on Facebook
Please do not distribute, repost, modify, or use my art in way away with out my permission first. Thanks so much
wow im terrible at doing hands and positioning this is gonna help a lot! It's great thanks ^^!
You're so welcome ^^ Hope it helps you!
two words: THANKS YOU ^~^
And this one.
Thank you very much
omg thanks for this tutorial
Awesome! THANK YOU!!!
Nice Tutorial
Is it okay using pencil instead of that drawing tablet thing?
Is it okay using pencil instead of that drawing tablet thing?
Before I saw this, my own hands wouldn't let me draw good hands. Now my hands are good at hands. What.
Amigo te mereces una medalla por esto, tan simple y tan bien explicado, las manos siempre se me habían hecho muy difíciles...pero con esto ya no otra vez gracias , seguiré practicando
Nya! Me encanta!
Really good form and I love your simplicity.
Thanks for sharing!!QAQ
Thank you, thank you, thank you so very much, drawing hands is the biggest pain in the ass ever
you are a real life hero, a true patriot to the artistic community
thanks, this is useful
I see you're an expert on this, and I can't draw hands so I guess I have no right saying this but
The ring finger is longer than the index finger
There is many types of hands, like many types of persons xD but yes :3
omg this is brilliant i didn't the about the joints, very helpful indeed
I heavily approve of this
Practice make perfect C: