text:
A quick update on CPP status:
Windows Vista RC1 is now publicly available. This means that 32- and 64-bit downloads for all three languages (English, German, and Japanese) are live. If you did not receive and email in the previous wave, you can now both download the ISO image and request a product key (PID).
More importantly, how do I get access to the RC1 build? Go here.
PingBack from http://farhanahmed.net/blog/?p=295
Just installed VISTA candidate 1 and now:
1) my HP 4110 all in one printer is no longer working.
2) HP says that the problem stems from IE 7.0 and they are working on a fix but in the meantime they suggested that I
A) remove IE 7.0,
B) Install 6.0
C) perfrom a level 3 uninstall of the exisiting HP driver software
1) It appears that I (system admin of my own machine) lack the authority to remove IE 7.0
2) You can't reinstall 6.0 over 7.0
3) I can't reinstall my previous XP home OS since VISTA ensures there is no going back.
4) I can't even find IE 7.0 in my list of installed programs using VISTA's control panel.
In addition to the chock-full-of-fun I'm having trying to undo the voodoo that you do so well, I am also having issues with other program that had previously been working under XP sp2.
System restores are worthless and other than scrubbing the hard drive, I am beginning to think I've made a grave mistake.
PS I am jealous.
As posted on the Windows Vista blog at 10 AM today... The public can sign up (in case you missed...
You can not uninstall IE 7 and install IE 6 in Vista.
That HP "support" person is just ignorant.
Keys are avail, but the EN / US 32bit download links do not work the moment!
PingBack from http://kevindevin.com/?p=2356
What shoud i do if that page says:
"Thank you for participating in the Microsoft Windows Vista Customer Preview Program.
You have received the maximum number of Product Keys available for this program. "
;(( but i lost my BETA 2 key, and i really want to have this RC1 for more than 14 days..... ;(
installed rc1 today, so far so good. a couple of driver issues and had to deep six roxio backup mypc. when windows one care becomes available for vista the roxio program will be redundant anyway. one thing, it seemed funny that "msn premium", does not work with vista. that seemed a little ludicrous but hey ms is a big company. looks like ie-7 for the time being. beautiful interface!
The links do indeed work, I just checked them.
I was wondering if AOL's antivirus software works with Vista RC1
PingBack from http://www.winajuda.com/2006/09/14/noticias/agora-e-oficial-vista-rc1-para-todos/
PingBack from http://37prime.com/blog/2006/09/14/windows-vista-rc1-customer-preview-program-is-available-now/
L'annonce à été faite hier sur le blog de l'équipe Windows Vista. Alors que jusqu'a présent les beta...
I have been trying since last evening at 5:00 EST and the website has said "Page Cannot Be Displayed" every time. I'm just going to the main page, selecting my country, and hitting Go - from there I just get a page that seems to be down. I've tried this from multiple computers with the same problem. Is something wrong here?
PingBack from http://vitorm.webhs.org/blog/?p=2804


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Regardz Airport Hotel Rotterdam4 Self rated
Vliegveldweg, Rotterdam, 3043 NT
Price FromView Rooms
This hotel doesn't have any reviews yet.
About the hotel
Regardz Airport Hotel Rotterdam is situated at Rotterdam The Hague Airport and close to the A13 motorway. Quick access to Rotterdam, Europoort but also The Hague, Scheveningen and Delft. With 200 parking places (free parking for hotelguests during their stay) in front of the hotel you can leave the car and get in to the city centre by bus in 15 minutes.
There is a direct connection to the city centre and Rotterdam Central Station with bus 33. All rooms have been renovated in 2010 and are trendy and up to date. With a walk in shower, FREE Wi-Fi, a flat-screen TV and coffee and tea facilities you' ll find all the comfort you need. Lunch and dinner are available in the restaurant that serves a range of Charrua Grain Fed Beef Steaks, delicious pagnotella sandwiches, various healthy salads and more. You can also have a bite or a drink in the bar/lobby. When it is sunny you can sit on the waterfront terrace and enjoy the green surroundings.
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Showing Sunday 14 February 2016 to Monday 15 February 2016Change Search
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- Hotel Non-Smoking Throughout , Disabled Facilities
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- Air conditioning in rooms , Safety Deposit Box , Tea/Coffee making facilities in each room , Hairdryer in each room , Minibar in each room , Telephone In Each Room
- Hotel services
- 24 Hour Reception , Limited Hours Room Service , Limited room service for hot food , Concierge , Laundry/Valet Service , Wake Up Call Available
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- Cots available , Interconnecting rooms available , Children's Facilities - Indoor , Children's Facilities - Outdoor
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- Wedding Licence , Doctor on call , Ground floor bedrooms , Lift to all floors , Public Air Conditioning
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- Car parking available onsite , Airport Shuttle
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- Disabled Access Public Areas , Disabled Access Bedrooms , Wheelchair Access , Wheelchair Access To Reception , Wheelchair Access To Restaurant , Wheelchair Access To Bar , Wheelchair Access To Conference Rooms , Wheelchair Access To Disabled Car Parking Spaces
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- Pets are not allowed
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subset: commoncrawl


text:
3 Reviews
Bergy......of course yours was good, you used pork tenderloin instead of the cheap cut, pork steak. You should not review a recipe if you change the main ingredient.<br/>This was ok but I believe it should be baked and not braised.
Loved the recipe. The hot salsa really gave the pork a lot of pep. I used 1/2" sliced pork tenderloin (I had it in the freezer I will make this again Thanks
I went back and forth on what to rate this recipe. 2 of 4 family members liked it and the other 2 weren't crazy about it. The flavour is wonderful but the juices in the pork really watered down the sauce. I think I would make this again and try baking it in the oven on a rack. Thank you for an easy recipe.


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- Mood: Joy
- Listening to: Lillica Libertine
- Reading: Halo: Ghosts of Onyx
- Watching: Flight of the Conchords
- Playing: The Orange Box
I'm starting to sell some shirts online over at RedBubble.com based on a lot of my artwork including my Video Girls series. If you don't know what Redbubble is, it's a lot like DeviantArt except with a focus on selling stuff (such as t-shirts). So go check it out, take a look at my shirts, and maybe start selling your own.
Also, thanks to Chamba for bringing it to my attention. Check out his DeviantArt here, and his Redbubble store here.
Video Girls Shirt 4 Sale by GuitarAtomikWatch
©2007-2016 GuitarAtomik


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Article Summary
Honda has announced an Intelligent Night Vision System for automobiles, which uses "far infrared" cameras to detect pedestrians in or approaching the vehicle's path. The system provides the driver with visual and audio cautions to help prevent accidents involving pedestrians. The new system will be available on the Honda Legend in Japan later this year.
Read the full article: Honda Develops Intelligent Night Vision for automobiles
Related Articles


text:
iHerb Customer Reviews
Love it!
Posted by Reviewer1242233 on Jan 06, 2010
It helps with my arthritis in the spine and help with my digestive system too. A great thing, thank you!
Great stuff!!!!!!
Posted by Reviewer1722975 on Jan 11, 2010
I had been using bromelain from another company but had never tried it with the turmeric. I really like it. I don't seem to need as much of it. I was taking 2 a day of the bromelain & I only seem to need one a day with this. Seems to help my stomach a lot. I'm hoping to get off the Nexium completely.
Turmeric & Bromelain, 450 mg, 180 Capsules
Posted by Reviewer2750972 on Feb 10, 2010
very good product.
Great product
Posted by Reviewer2466786 on Mar 01, 2010
I just began taking this product for my MS after reading that the anti-inflammatory properties helped reduce the exacerbations. I just started taking it, so I cannot say whether it helps or not. However, iHerb shipped very quickly and this is a quality product. Thanks, iHerb!!
Posted by Reviewer3309545 on Mar 06, 2010
very good


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TDB 45 'Epic Baby' by ShadowMaginisWatch
©2011-2016 ShadowMaginis
So World Of Warcraft has already lost 600,000 players this year. Jen and I actually started playing again and I enjoy it. I think the problem is that they are making it eaiser for casual players like me to get really good gear, but the hardcore raiders that play everyday are going through the new content a week or two after it is released and getting bored.
newest comic here! [link]
newest comic here! [link]
PPL getting bored with WOW?! XD


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When I installed the latest Apple TV update, I no longer had access to Photostream. My Apple TV said I had to accept the new Terms of Service before I could sign in to my Photostream account. I followed the directions for both my Ipad, and my Windows 7 computer and in neither case was I able to access the new Terms of Service as described. Any suggestions?
(I have not upgraded to IOS 6 on my iPad)
Retrieving data ...


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Out of the Past: Railroads & Sovereign Debt Restructuring
Lubben, Stephen J., Georgetown Journal of International Law
Railroad receiverships are suddenly relevant again. Long before the enactment of the first corporate reorganization statutes in the early 1930s, the federal courts developed a method of reorganizing financially distressed corporations, especially railroads, within the existing architecture of the equity receivership. From 1850 to 1932, these receiverships were the only way to reorganize a large American corporation. The last major railroads to go through receiverships completed the process decades ago. (1) Yet today, more than twenty years into the problem of widespread sovereign financial distress, (2) several leading scholars have begun to ask if railroad receiverships might hold important insights into sovereign debt restructuring. (3)
The analogy between the railroads of old and the sovereign nations of today rests on two key points. First, like sovereign borrowers today, early American railroads faced financial distress without the benefit of an applicable bankruptcy statute. Second, liquidation was no more an option for the railroads than it is for a sovereign nation. In this context, the development of the equity or railroad receivership seems to hold many promising lessons for reorganization of today's troubled sovereign borrowers.
This Paper takes a closer look at the analogy between railroads and countries to see if it holds beyond its superficial appeal. In particular, I examine how railroad receiverships addressed the problems of holdouts and individual creditor action--the key stumbling blocks for most approaches to sovereign debt restructuring. (4) I argue that receiverships overcame these problems in ways that could be useful for sovereign borrowers.
But the utility of receiverships should not be overstated. Railroad receiverships operated in an age when federal equity jurisdiction was at its peak. This allowed the courts to exert significant power that might not hold today. Moreover, the receiverships were essentially in rem proceedings that allowed a district court to exercise its power irrespective of the geographic dispersal of railroad bondholders. (5) This power is of limited application in the sovereign debt context, as most sovereign assets are beyond a U.S. court's in rem jurisdiction. Finally, and most importantly, a good deal of the receiverships' apparent success in dealing with holdouts resulted from the generous treatment of existing creditors. This generosity may have limited the long-run effectiveness of the receiverships. (6)
This Paper proceeds in three parts. Part I outlines the workings of railroad receiverships in general and then focuses the discussion on the ways that receiverships addressed holdouts and individual creditor actions. Part II presents the strongest case for using receiverships as the basis for a new model of sovereign debt restructuring. This "strong form" version of the analogy exceeds anything presented in the existing literature and highlights the full potential of receiverships in the sovereign debt context. Part III qualifies the analogy in Part II by discussing the limits of receiverships and the difficulties in applying to sovereign nations a tool that was developed for a set of uniquely American debtors.
In short, I am cautious about the utility of deploying railroad receiverships in the sovereign debt context. Plainly there are historical lessons awaiting application, but only selective and considered reference to the early days of corporate bankruptcy will translate into meaningful improvement of sovereign debt restructuring.
"Most of the great [American railroads] had been built by fraudulent construction companies, and if perchance a road had been honestly built, there was always an opportunity to correct this oversight by disreputable, but highly profitable, manipulation of its securities." (7) Self-dealing, combined with sprees of overbuilding, meant that railroads faced major bouts of financial distress in 1857, 1873, 1893, 1908, and, of course, the early 1930s. …


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Pepperoni Mushroom Pizza Dip Recipe
5 5
Folks will dig into this rich pizza-flavored dip from Donna Cajski of Milwaukee, Wisconsin. It's loaded with tasty toppings including pepperoni, mushrooms, olives and cheese, then warmed in the microwave.
- 1 package (8 ounces) cream cheese, softened
- 1 can (4-1/4 ounces) chopped ripe olives, drained
- 1 can (4 ounces) mushroom stems and pieces, drained and chopped
- 1/3 cup chopped onion
- 24 slices pepperoni, chopped
- 1 can (8 ounces) pizza sauce
- 1 cup (4 ounces) shredded part-skim mozzarella cheese
- Assorted crackers
- Spread the cream cheese into an ungreased 9-in. microwave-safe pie plate. Top with olives, mushrooms, onion, pepperoni, pizza sauce and cheese.
- Microwave, uncovered, at 70% power for 7-10 minutes or until heated through and cheese is melted. Serve with crackers. Yield: 8-10 servings.
Editor's Note: This recipe was tested in a 1,100-watt microwave.
Originally published as Pepperoni Pizza Dip in Quick Cooking January/February 2005, p61
Reviews for Pepperoni Mushroom Pizza Dip
Please Log In or Join to add a rating and review.
Click stars to rate
Any changes to your rating or review will appear where you originally posted your review


text:
From Our Friends
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What is a good raw vegan recipe?
trampledbygeese is a trusted home cook.
There is a really yummy dessert that you can make from cocoa powder and avocado that does not require cooking and can be made vegan. I think it's called 'avocado chocolate pudding', and there are lots of versions of it. (just have to keep an eye out for recipes that include honey, it's not a vegan friendly ingredient)
This one looks really good: http://www.choosingraw... Haven't tried it myself yet.
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From Our 2008 Archives
Dermatitis Can Have Many Causes
Latest Skin News
THURSDAY, Nov. 6 (HealthDay News) -- A wide variety of substances can cause the skin condition known as contact dermatitis, which often can be effectively managed with proper diagnosis and treatment, experts say.
Contact dermatitis is an acute or chronic inflammation of the skin resulting from contact with a chemical, biologic or physical agent. Common culprits include cosmetics, perfumes, certain foods, nickel and some other metals, cleaning solutions, detergents, industrial chemicals, and latex rubber.
The majority (20% to 35%) of all dermatitis cases affect the hands, including more than 75% of work-related contact dermatitis cases, according experts at the annual meeting of the American College of Allergy, Asthma & Immunology (ACAAI) in Seattle.
"Allergic contact dermatitis of the hands is very common among certain occupations. This includes health-care professionals, hairdressers and cosmetologists, woodworkers, machinists, and chemical workers," Dr. James. S. Taylor, director of the Section of Industrial Dermatology at the Cleveland Clinic in Ohio, said in an ACAAI news release.
Patch testing is important in diagnosing hand dermatitis, since allergic contact dermatitis may occur alone or in conjunction with irritant, atopic or other forms of dermatitis, Taylor said. Treatment depends on the cause of the dermatitis.
"For allergic contact dermatitis, it involves allergen omission or substitution and generally using topical or occasionally systemic corticosteroids to relieve the symptoms," Taylor said.
The second most common sites for dermatitis are the face and eyelids, often due to a reaction to a cosmetic, soap or other personal care product.
"The patient has often switched to a new brand of makeup or a different cleanser right before the skin outbreak occurred. We will usually treat the condition with a topical corticosteroid and have the patient stop using the product," Dr. Vincent A. DeLeo, chairman of dermatology at St. Luke's-Roosevelt and Beth Israel Medical Center in New York City, said in the ACAAI news release.
Patch testing usually isn't necessary in cases of face/eyelid dermatitis, but may be warranted if the patient continues to have flare-ups despite changing skin care products and receiving topical treatment, DeLeo said.
-- Robert Preidt
SOURCE: American College of Allergy, Asthma & Immunology, news release, Nov. 6, 2008
Copyright © 2008 ScoutNews, LLC. All rights reserved.
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Vercors by vincentfavreWatch
©2011-2016 vincentfavre
[Vercors - Grand Veymont - FRANCE]
Amazing nature, fantastic photos!
a beautiful photo!
Très belles composition de courbes et de ligne, cette perspective est très douce.
Amazing place.
Great shot.
Great shot.
This is amazing
Beautiful shot, especially for composition
I just wish you uploaded a bigger image
I just wish you uploaded a bigger image
great shot
i like it when there are more trees but this one looks great
i like it when there are more trees but this one looks great
I didn't know there were such wonderful views in my own country ! Thanks for this awesome picture !
awesome picture
Nice angle, very peaceful
quelle symétrie
a wonderful sense of space and freedom!
i love all the wonderful angles!
i love all the wonderful angles!
Reminds me some landscapes from the Peter Jackson's "LotR" trilogy.
great pic
such a beautiful place
beautiful scene
Beautiful !!
wow beautiful composition, great shot!
wow nice shot!


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Indian Institute of Science
Instrumentation and Applied Physics
The department offers two research programmes, which lead to award of Ph.D., M. Tech ( Research) and a course programme that leads to award of M.Tech. degree.
An information about the eligible criteria to get admission in different programmes is provided below. For more information please visit
addmissions page.
ELIGIBILITY FOR ADMISSIONS TO Ph.D./M Tech (Research)
M.E./M.Tech./M.Sc. (Engg.) degree holders
Candidates with B.E./B.Tech.or equivalent degree in Instrumentation or Electrical and Electronics Engineering or M Sc or equivalent degree in Physics / Engineering Physics / Applied Physics, Materials Science, Electronics will be considered for Ph.D. programme only.
Slection of shortlisted candidates for interview will be decided by the selection committee.
M.Sc. (non-Engg.) degree in Applied Physics/ Material Science/
Electronics holders
Candidates who have qualified any one of the national tests, such as JEST, Joint CSIR-UGC-NET for JRF (candidates who have qualified NET for lectureship (LS) only are NOT eligible to apply) / GATE (with valid score card within the validation peiod) will be considered for admission to Ph.D. programme and / or M. Tech ( Research) programme based on their performance in the interview.
B.E./B.Tech. degree holders
Candidates with B.E./B.Tech.or equivalent degree in Instrumentation, Electrical & Electronics with valid GATE certificate within the validation period will be considered for admission to Ph.D. programme and / or M. Tech. (Research) programme based on their performance in the interview.
ELIGIBILITY FOR ADMISSION TO M.Tech
B.E./B.Tech. or M.Sc. (non-Engg.) degree holders
Candidates with B.E./B.Tech.degree in Instrumentation / Engineering Physics /Applied Physics / Electronics ( GATE paper in IN , EE, EC ) OR M Sc or equivalent degree in Instrumentation / Physics / Emgineering Physics / Applied Physics / Electronics ( with a GATE paper in relevant dicipline ) will be considered. All the candidates should qualify GATE (with valid score card in the validation period). Final selection list will be prepared by selection committee based on GATE score and other criteria as per IISc selection procedure.
Graphene Electronics, Micro and nano systems. Sensors and related Instrumentation, Nanoscale Imaging, Super-Resolution Microscopy and Imaging, Fluorescence Microscopy Precision Motion Control, Microfluidics and Devices,Nano-metrology, Atomic Force Microscopy, Semiconductor Devices and Circuits, Bioinstrumentation, Tomographic Imaging for Biomedical and other Applications, Materials Engineering, Lasers and Spectrometry, Photovoltaics, Laser and Optical Instrumentation, Analytical Instrumentation, Electrical and Thermal Contact Resistance, Microelectromechanical Systems (MEMS), Fibre-Bragg Grating Sensors. Plasma Processing and Thin Films, Solar Energy and Thermal Instrumentation, Vacuum and Thin Films, Phase Change Memories. Energy Systems, Image Processing, Semiconductor Devices and Circuits, Control Systems, Materials Engineering, Microscopy and Imaging, Analytical Instrumentation, Electronic Instrumentation, Lasers and Optical Instrumentation, Microfluidic Devices, Solar Energy and Thermal Instrumentation. For more detailed information please visit
Department Research
© 2013 Instrumentation and Applied Physics |


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Norwescon 39 is just around the corner (57 days!) and yesterday I received my tentative schedule! Last year I ran my table and had a blast. 767 more words
Tags » Upcoming Appearances
Come See Me At Lilac City Comicon
We're about two weeks away from Lilac City Comicon 2015 in Spokane, Washington. The event runs one day, May 30th, and I'm happy to say I will be there alongside the incredibly talented… 116 more words
Regarding the vanishing American e-books, my agent tells me that Overlook has recently switched distributors, and that the kerfuffle will be sorted out shortly. If you decide to pass this along, please take the opportunity to shame those who illegally download. 196 more words
My CthulhuCon Schedule
Since we're now less than a week away from the start of CthulhuCon in Portland, Oregon. Since I'm an active participant I figured it'd be handy for me to post my schedule. 462 more words
Come See Me At CthulhuCon
We're now a week and a half away from CthulhuCon in Portland, Oregon. This convention is an official spin off from the H.P. Lovecraft Film Festival… 145 more words
Come See Me At NorWesCon 38
We're only a couple days away from NorWesCon 38 here in Seattle, Washington. I will be there along with copies of The Stars Were Right… 116 more words
Gratitude & Room for Contemplation
I have wrapped up my last performance of 2014.
Performing this show has continued to create powerful ripples in my consciousness about healing from community wounds and the pedagogical power of remembering injustice. 138 more words


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Journal of Health Care for the Poor and Underserved
Volume 23, Number 2, May 2012
pp. 519-522 | 10.1353/hpu.2012.0062
Advancements in modern technology have brought tremendous changes in human behavior. One such change is in modes of communication such as text messaging, or texting. This form of communication has emerged as one of the dominant modes of communication in the world. This report presents a differential pattern of texting seen during the manic episode of a young adult with bipolar I disorder. We observed all the DSM IV manic symptoms; interestingly the patient's predominant medium for communication was texting. The patient reported a dramatic increase in the quantity of both texting and sex-texting (or sexting) in addition to a decrease in quality of the message content. In addition, there was a substantial increase in the number of people with whom the patient engaged in simultaneous texting conversations. This case provides evidence for the need to consider non-traditional forms of communication when evaluating a patient's communication pattern during mania.
You must be logged in through an institution that subscribes to this journal or book to access the full text.
If you continue to experience trouble, please contact technical support.
If you continue to experience trouble, please contact technical support.


text:
When I interviewed Darren Aronofsky in New York four weeks ago, it was the first time I had heard him discuss his film Noah in the context of midrash, a form of Jewish narrative interpretation of the scriptures. But he has certainly brought it up quite a bit in the interviews he has done since then.
For example, it's right there in the headline that sits atop the interview that Huffington Post religion editor Paul Brandeis Raushenbush did with Aronofsky and his co-writer Ari Handel ('Noah: A Midrash by Darren Aronofsky and Ari Handel'). A couple sample quotes:
[Read more...]


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110 2nd Street South, Suite 301
Waite Park, MN 56387
Processus is a Multidisciplinary Counseling and Organizational Consulting Center in Waite Park, MN. We began in 1980 and have grown into a diverse team of Mental Health Professionals and Administrative Professionals. Our mission is to provide compassionate, ethical, high quality psychotherapy and mental health counseling services in a friendly, vibrant and caring work environment.
Our unusual name conveys something important about us. "Processus" implies that life is a process -- a journey marked by critical periods. Specialized help is sometimes necessary to pass through these periods. That's where we may come in. Our aim is to be helpful as needed and only as long as needed. We see ourselves as one of many in a sustaining network of community resources.
"Processus" also suggests that we each proceed in our own way, one that carries a certain wisdom or rhythm which must be understood for the helping process to succeed. Select from the links on this page to learn more about our services.
Counseling and Consulting Services


text:
Tell us about your employees' FR needs and find out if your company qualifies for a wear trial.
Get in touch with a DRIFIRE Distributor near you for small-quantity or large-quantity orders.
See the latest in DRIFIRE's high performance FR clothing for your industry.
Born on the battlefield, proven on the track and trusted by the most high-risk industries, DRIFIRE high performance FR offers protection where and when it matters most.
Our full line of inherent flame resistant clothing is made tough to endure even the most hazardous conditions. Yet, it's lightweight and comfortable to help you stay focused on the job at hand.
Would you bet your life that you know for sure the clothing your workers wear meets the highest standards to protect them from flash fire and other hazards like heat stress? You are betting their lives … everyday. Get the facts. With so much innovation and increased regulation, you want to be confident you are selecting the correct, most comfortable apparel so all your workers return home safely to their families every night.
Register at BIC Magazine to learn how to improve compliance and reduce recordable injuries by protecting your workers with the right flame-resistant clothing.
While American workers are becoming more aware of high-performance, flame-resistant (FR) and moisture-wicking technologies, it's even more important to understand the science behind them. This is especially true if you work in outdoor or higher-risk industries. Our combined past experiences as oil rig workers, scientists, fabric technologists, outdoor enthusiasts and sportsmen offer us unique insights on why you should be wearing high-performance FR garments.
I'm in rubber gloves and sleeves almost every day in 90+ degree weather, in a regular cotton FR shirt I'll be wet and smelly all day long. Not in this FR midweight long sleeve tee, because my arms dry out in minutes…
Having just come back from the Middle East I can say with great confidence and absolute certainty – my personal gear will always contain DRIFIRE products!
The DRIFIRE boxer briefs are without a doubt the most comfortable underwear that I own…they don't hold moisture during long flights like others.
We found that DRIFIRE gives our safety crews and pit technicians the optimal balance between flame resistant protection and athletic performance so they can stay comfortable to focus on the tasks at hand.


text:
Your Shopping Cart is empty.
Give it purpose - fill it with water filters, air filters, refrigerator filters, and more.
The PUR W10186668 Replacement Water Filter Compatible is a refrigerator water filter for Whirlpool side-by-side refrigerator models with easy access through the front base grille. This PUR water filter reduces sediment, chlorine taste and odor, dirt, rust, cysts, and lime scale build-up in drinking water and ice. The W10186668 water filter features a flow rate of 0.5 gallons per minute and a pressure range of 30-120 PSI.


text:
Narrow your search
Though pricey, the WRT1900ACS' long range and rapid Wi-Fi will deliver fast Internet to places in your home that other routers might struggle to reach.
The top routers that support the new 802.11ac standard on the market. Since there aren't that many of them, all of those on this list are the best of their kind.
Homes with lots of devices will benefit from the Linksys EA8500's speedy Wi-Fi and storage performance, but those with modest needs should look for something cheaper.
The WRT1200AC is just way too expensive for a second-tier 802.11ac router.
Only those who do a lot of local intensive tasks via Wi-Fi, or who can appreciate the Asus RT-AC3200's excellent feature set, will find this router worth the investment.
The ZyXel Homeplug AV2 Gigabit Powerline Adapter Starter Kit is currently the fastest way to extend a network to a place in your home where your Wi-Fi signal can't reach.
The hefty price aside, the Asus AC2400 RT-AC87U is the most complete 802.11ac router to date, capable of satisfying all your home networking needs.
So long as you're not a networking newbie, the Totolink A2004NS AC1200 Wireless Dual Band Gigabit Router is a good deal for those living in a small or medium home.
Even when it's working well, the Netgear R8000 Nighthawk X6 AC3200 Tri-Band Gigabit Wireless Router has nothing to justify its expensive price tag.
Despite a few minor shortcomings, the DIR-880L is still one of the best 802.11ac routers on the market.
From the Cheapskate: This refurbished router scored high marks from reviewers and buyers alike. It normally sells for at least $100 more.


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Does the Shake Weight Work?
I'm a sucker for infomercials. I could waste a whole afternoon dreaming of melting inches off my waist with a simple DVD or device.
Ivillage.com recently reviewed ten weight loss products sold on infomercials to see if they live up to their claims. The one I was most interested in? The Shake Weight. Surprise, surprise it doesn't work! (Though I still get an ab workout from laughing at the ridiculous infomercial).
See how the other nine products faired?
While there are a few items on ivillage's list that do in fact work, it's important to keep in mind that there is no quick gimmick that can replace good, old fashioned exercise and healthy eating.
Source: ivillage.com
Check out our reviews of As Seen on TV products. We loved Debbie Meyer Green Bags to help produce stay fresh longer.
Learn how to build a home gym without spending a lot of money.
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And about to get a whole lot healthier.
Just found the worst page in the entire dictionary. What I saw was disgraceful, disgusting, dishonest, and disingenuous.
Client: We need you to log in to the YouTube and make all our company videos viral.
From clientsfromhell.net
My cat just walked up to the paper shredder and said, "Teach me everything you know."
"Just because you can't dance doesn't mean you shouldn't dance." —Alcohol
@yoyoha (Josh Hara)
My parents didn't want to move to Florida, but they turned 60 and that's the law.
—Jerry Seinfeld
Q: What do you call an Amish guy with his hand in a horse's mouth?
A: A mechanic.
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More About Fitness
11 Fitness Myths We Should Stop Believing Already, From Dr. Oz's Personal Trainer
Do crunches flatten your stomach? The more you sweat, the more fat you lose, right? Donovan Green, personal trainer to Dr. Oz, debunks common fitness myths that could be sabotaging your weight-loss goals.


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I have worked with individuals that have had difficulty coping with addiction, anxiety, trauma, depression, grief & loss, relationship, and LGBT issues. I care deeply about my clients and want your therapeutic encounter to be a healing experience.
Dr. Craven has all of the credentials to prove her outstanding training (Texas A&M, APA accredited training, licensure, etc), but just as important, she puts her heart and soul into her work as a psychologist and fully dedicates her life to this vocation.
A therapist in West University Place TX is a skilled and trained expert able to help you navigate difficult challenges. If you are in need of the services of a West University Place TX therapist, click on any professional above to make contact.
Welcome to our network of West University Place TX therapists. Professional Texas counseling and therapy with compassionate values can help you navigate life's hurdles. If you are seeking a therapist West University Place TX, we are ready to listen. Choose any West University Place therapist below to learn more and obtain contact information. Therapy from a licensed West University Place TX therapist with Theravive is a powerful tool to bring lasting changes in your life.
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Theravive does not provide medical advice, diagnosis, or treatment.
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The Works, In WaxThe Works, In Wax (1993) Season 1 Episode TAL-06- Tales From the Cryptkeeper Cartoon Episode Guide
This page has been viewed 8 times this month, and 494 times total.
- Tales From the Cryptkeeper Cartoon Episode GuideEpisode GuideTelevisionSeriesCartoon
- Traditional Animation
- Nelvana Limited
- Animation Studio: Wang Film Production, Bardel Animation, Medallion PFA, International Image, Studio 306
- Cartoon Characters: The Cryptkeeper, Frank Hancott, Mrs. Crumm, Stu, Dwight, Boswick, Craig, William, Monster Hunters.
- Voice Actors: John Kassir, Don Dickenson, Lorna Wilson, Noam Zylberman, Daniel DeSanto, Cedric Smith, Stuart Stone, George Buza, John Stocker, Judy Marshak; Full Voice Cast ...
- Directed By Laura Shepherd.
- Produced By Michael Hirsh, Patrick Loubert, Richard Donner, David Giler, Walter Hill, Joel Sillver, Robert Zemeckis, Steve Hodgins, Alex Collett; more Producers ...
- Written By Eric Luke.
- Editor: Rob Kirkpatrick.
- First Aired on October 16, 1993.
- Originally Aired on ABC-TV (USA).
- Running Time: 30 minutes.
- Episode Number: TAL-06
- Season: 1
- Color
- U.S.A. / Canada
Cartoon Summary:
A boy discovers that statues in his favourite wax museum come to life.
Cartoon Production Information:
Much like the series (and EC comics) that the cartoon was based on, the show featured different child characters weekly who ended up in twisted situations, but with a little more morality play than the HBO series. In this second season episode,... (more)
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Cartoon Comments:
Do you love The Works, In Wax, or do you think it is the worst cartoon ever? Let us know what you think! Surely you have an opinion... so share what you think. Take a minute and post your own comments about this cartoon here.


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07/08/2013 | Canada Seeks New 472-479 kHz Ham Band
Canadian amateurs may soon have access to 630 meters.
Learn More
04/02/2013 | J. Kenneth Pulfer, VE3PU (SK)
J. Kenneth Pulfer, VE3PU, of Ottawa, Ontario, passed away Sunday, March 31 after a long illness. He was 80. In 1994, Pulfer became the Secretary, then Secretary Treasurer for the Radio Amateurs of Canada (RAC), that country's IARU Member Society. He also
Learn More
01/21/2013 | Icelandic Amateurs Get MF Privileges
According to the Íslenskir Radíóamatörar (ÍRA) -- Iceland's IARU Member Society -- radio amateurs in Iceland now have operating privileges on 472-479 kHz (630 meters) as of January 16.
Learn More
01/03/2013 | Comment Deadline Set in WRC-07 Implementation Proceeding
As previously reported, the FCC has proposed to amend its rules to implement the allocation decisions of the 2007 World Radiocommunication Conference (WRC-07) and to make certain other changes. Notice appeared in the December 27, 2012 issue of the Federal
Learn More
Feature01/02/2013 | ARRL in Action: What Have We Been Up to Lately?
This feature -- including convenient web links to useful information -- is a concise monthly update of some of the things the ARRL is doing on behalf of its members. This installment covers the month of December.
Learn More
12/10/2012 | ARRL Files Petition for Rulemaking with FCC to Create New MF Band at 472-479 kHz
The ARRL filed a Petition for Rulemaking on November 29, asking the FCC to amend Sections 2 and 97 of its rules and create a domestic Amateur Radio allocation at 472-479 kHz, conforming to the allocation status and limitations set forth in the internation
Learn More
11/08/2012 | ARRL Executive Committee Examines Regulatory Matters, Organizational Issues and More at September Meeting
The ARRL Executive Committee (EC) held its second 2012 meeting Saturday, September 29 in Denver, Colorado.
Learn More
09/18/2012 | Looking Ahead to WRC-15
From an Amateur Radio perspective, the 2012 World Radiocommunication Conference (WRC-12) was very successful. According to IARU Secretary Rod Stafford, W6ROD, the IARU Administrative Council will meet in the next 45 days and will address the agenda items
Learn More


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Rapid identification of viable bacterial spores using a fluorescence method.
Citations & References
- Authors: Sharma DK, Prasad DN
- Journal: Biotech Histochem (1992) 67:27-29
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Translation of cartridge case in Spanish:
- cartuchera (feminine)
estuche (masculine) para cartuchos
What do you find interesting about this word or phrase?
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Grammar and usage help for Spanish:
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Always wanted to do a redesign for the U1's Mac client. Had some time lately so I finally did it.
Is this a sketch or actual software?
Outstanding design. well done
very beautiful!!
I agree with UbuMachine Nice design
this should be the default for the native ubuntu one for ubuntu


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Synonyms of profile in English:
verbBack to top
- keep a low profile
- in matters concerning his family, he managed to keep a low profilelie low, keep quiet, keep out of the public eye, avoid publicity, keep out of sight
Definition of profile in:
- British & World English dictionary
- US English dictionary
- English synonyms
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I'm looking to execute an external program through the command line, but I've found I'm only able to do so if the program exists in the directory I am calling it from. I would like to be able to execute the program from any directory.
I've set the Path variable for windows (7) and am able to execute the program from any directory manually with the command line; however i am unable to do so through Java.
Relevant code:
Runtime rt = Runtime.getRuntime();
Process proc = rt.exec(new String[]{"C:\\AutomateKPI\\GetLog.exe", "-e", rossIP});
My issue is that the output of the above program produces a generically named file "log.txt". This will cause problems when threading my program. If it is impossible to use the path variable, alternatively i can copy the program into the new directory and delete it afterwards. I would like to avoid doing so.
Edit: The above code works as GetLog.exe resides in C:\AutomateKPI. I would like to reference %PATH% so I can run GetLog.exe from C:\AutomateKPI\*NewDir*


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My son will be 4 in 2 weeks.Ā I want to get him either the LeapPad or Inno Tab for his birthday or Christmas this year. I don't know which one to get - it's so hard to decide just from looking at the product descriptions online. I'm going to see if I can find demo models at any local stores to try them both.Ā Has anyone done any research and compared these? Or in general, has anyone tried the other Leap Frog and vTech game systems and if so, which company's games and systems do you like better? That could help show if the LeapPad or Inno Tab has more potential to be better than the other! TIA!
LeapPad vs vTech Inno Tab
Me 31, DH 31, DS 10/07, DD 11/12, #3 Due 3/14
MTHFR c677T Homozygous
I'd like to know, too! I think the LeapPad *looks* cooler, but yeah know..not a great buying criteria :)
Ashley (26): Wife to J (27) for 3 years! Step-mommy to M, 7, and C, 6. Mommy to Trevor, 2, and Nathan, 1!
My son will be 4 on Dec 17th and I just purchased the Leap Pad for his upcoming birthday. Last year I got him the Vtech Mobigo hand held system and he absolutely loves it!!!┬ĀThis year I am choosing the Leap Pad because of its many application options, the cartridges are a lil cheaper than the Vtech Innotab (especially if purchased from AMAZON), and it┬Āalso has a built in camera and video recorder and comes with 2BG of memory!!!! The Leap Pad is priced at $99 and the InnoTab is priced at $79, but I think the Leap Pad is still a better buy with more options.
I was going to purchase the Leap Frog Digital Camera for him, but when I found out about the Leap Pad, I chose against it┬Ābecause I can get him the Leap Pad system and it will be like getting the camera, video recorder, and a touch-screen system all in one.
I know that I sound like┬ĀI am spokesperson for the LF Leap Pad (LOL), but I did extensive research┬Ābefore making my purchase, as I always do before buying things for him.┬Ā
I've been wondering the same thing. FYI: Best Buy usually has these type of things set up for demo. I don't live anywhere near one so it has been awhile since I've been in one so I don't know first hand if they have the Leap Pad. I know that they had the Leapsters the last time I was there so chances are good that they would have it.
- Kristin
Mom to my beautiful, creative, imaginative little girl,ĀLorelai Katherine (12/23/07)
Wow,I had no idea Vtech had one of these things too. I'll have to check it out. I was just going to buy the leap pad it sounds/looks so cool. I have the vtech vreader for DS and he lovessss it. I did get him the leapster 2 the year before that and he never really liked it too much. He still does play it from time to time, but he always favors the v reader. The leapster 2 has pretty bad graphics and the screen is so small IMO, so hopefully the leap pad is better in that department. I mainly want to get him it b/c he takes mine and SO's ipod/pad and takes millions of pictures with it and kills the memory and I have to delete them 1by1 (is there a way to delete in bulk?) so I can't wait for him to have his own camera
Together with my Love since 06/06/2006.
Big Brother Aiden Arthur
Lil' Bro Tristan James
I just read that the vTech one does not have a camera or video camera. It also has smaller memory but you can expand it with a chip. The Leap Pad has 2GB memory built in.
I had another post and someone gave me this link to a comparison: buythebestreviews.com/vtech-innotab...
There must be some sort of MP3 thing on the Leap Pad or maybe an app we can download. So I decided on the Leap Pad...
Me 31, DH 31, DS 10/07, DD 11/12, #3 Due 3/14
MTHFR c677T Homozygous
I haven't read all of the comments...but I am looking at getting the innotab for my 4 year old daughter. ┬ĀI've read online that the only difference from the leapad is that it doesn't have a camera/video recorder. ┬ĀThe applications are the same price, but for the innotab, you get 5 applications per cartridge vs 1 application per cartridge for the leappad. ┬ĀThe innotab is touch screen vs the loseable pen for leappad. ┬ĀThe innotab appears to lose battery life quickly, but there is an AC adapter for countinuous play rather than changing the batteries constantly. ┬ĀThey are also expanding the library for V-Tech (the makers of the innotab). The innotab has an MP3 player and has added memory cards for extra memory. ┬ĀHeadphones work for the MP3 player so your surroundings won't be disturbed!
Hope this helps! ┬ĀI'm super exicted for my daughter!
The Leap Pad is also touch screen and has an AC adapter you can use to plug it in. ┬ĀFor us the camera was a big reason we chose the Leap Pad. ┬ĀAlso, we have always had good experiences with Leapfrog stuff. ┬ĀPlus I had a few friends who had gotten their children the Leap Pad so I was able to get reviews and info from them and I don't know anybody who has the Innotab to talk to.
April - Mom to twins Zak & Ryder (born 8/5/07, 30 weeks) and Tyler (born 4/26/12)
I have been wondering the same thing.┬Ā Thanks for the feedback.
Yaya... aka "Mommy Mogul"
Chamberlain 11/05/07 & "Sir" Garrett, II June 02, 2010
I just brought the InnoTab for my daughter who is 32 months after doing extensive research, including reading this blog :). I brought the InnoTab because it has an MP3 player and I am able to download videos. These features are not available in the LeapPad. My child prefers to listen to music and watch movies over table pictures and making movies. That is her preference. I also like the fact that the apps are cheaper. I did not buy any cartridges. I just brought some learning and game apps. I also brought an 8GB SD card which allowed me to put 4 movies and over a hundred songs on my daughter's InnoTab. The ability to increase the memory was a selling point to me. I also liked the fact that I could use and AC adapter along with any headphone. I have rechargable batteries but the AC adapter is just easier for me. I also hate listening to kids music and movies so the headphones are a blessing. These are my reasons. Hope this is helpful to someone.
You must be the change you want to see in the world. Mahatma Ghandi


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On Youtube! If you do use this tutorial, credit would be highly appreciated (a link to the video would suffice!).
These were my childhood dessert. It makes my mouth water..mmm
You are without a doubt one of the most talented polymer clay artists I've ever seen! Thank you so much for sharing your knowledge , it is much appreciated.
I'll definitely try this sometime, if I can change the color so it looks like key lime bars
Those are fake....?!
great job!
A very nice tutorial. You are so multi talented it is amazing. There are some good ideas in this tutorial. Ones that I have not seen elsewhere.
That was really cool! Thanks for sharing!
So good! And very helpful!
i love your tutorials *.*
These look more realistic than the real lemon bars that my mom and I made a few weeks ago.
So cute! Such fine detail I really like this piece! You did very well.
I know how to make actual lemon squares. lol. And you got these dead on in detail. Just amazing. . . Now I want lemon squares. n_n
Looks so scrumptious! ♥
Your work is always amazing and a pleasure to see. )
Your work is always amazing and a pleasure to see. )
Neat, I think I shall try this!


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Dergun by KatePfeilschiefterWatch
©2012-2016 KatePfeilschiefter
superbe dragon felicitation
fucking epic.
Dem teef. <3
Love it!
Nice character design I love those oddly curved horns...and what appear to be... whiskers? I wonder if he purrs
First I thought it's a t-shirt so I guess it would be perfect for a shirt print!
cool, nice pencil work!
thats a beautiful dragon.
Sketchy goodness!
Unique dragon! I love the details.
Spetacular, congratulations! Very well done...
Thought it was a T-shirt on the first sight xDD
This maybe a very random comment but: You should print this on a t-shirt. It has the perfect shape for it. <3
you have awesome sketching skills
F**king awesome!!!!!!
that one amazing dragon
Wow! it has a surprisingly 3d look to it! Amazing linework!
The way you subtly handle the jaw line with texture wrap around instead of line, that's so good dude.
Scary Face
Very solid-looking. Looks perfect.
badass dragon love it
Love it!! Hope he's friendly- and not just thinking about what (or who) he might have for lunch...
grizzley fellow hope he's friendly
Random dragons are great dragons, love how you draw them. This guy looks really proud!


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Bookmarks: Recently released nonfiction books
Here are some books that have crossed our desks recently.
"SWIM: Why We Love the Water," by Lynn Sherr, Public Affairs, $25.99, 212 pages (nf)
A look back through the history of swimming with facts and anecdotes and how it has evolved, along with Lynn Sherr's own journey of swimming the wild waters of Hellespont.
"AFTER CAMELOT: A Personal History of the Kennedy Family 1968 to the Present," by J. Randy Taraborrelli, Grand Central Publishing, $29.99, 602 pages (nf)
The sequel to "Jackie, Ethel, Joan: Women of Camelot" (now out in paperback), "After Camelot" explores the Kennedy family after the assassination of of President John F. Kennedy to the present and includes interviews, details on the political rivalry between the Shrivers and Kennedys and the challenges by the third generations of the families.
More hardback books recently released:
"THE 4 DISCIPLINES OF EXECUTION," by Chris McChesney, Sean Covey and Jim Huling (nf): After studying why execution of worthwhile goals in businesses fall short, the authors provide a formula to help achieve these necessary goals.
"GIANT GEORGE: Life with the World's Biggest Dog," by Dave Nasser with Lynne Barrett-Lee (nf): Dave and Christie Nasser adopted a Great Dane they named George, who was the runt of the litter, that grew to almost five feet tall and seven feet long and was listed in the Guinness Book of World Records.
"CALLS BEYOND OUR HEARING: Unlocking the Secrets of Animals Voices," by Holly Menino (nf): After a horseback riding accident left nature writer Holly Menino with some hearing loss, she became aware of animal voices and the role it has in their survival.
"MIDNIGHT IN PEKING: How the Murder of a Young Englishwoman Haunted the Last Days of Old China," by Paul French (nf): A look into a 75-year-old unsolved murder of a British schoolgirl.
"SUMMER OF '68: The Season that Changed Baseball — and America — Forever," by Tim Wendel (nf): Despite the tumultuous year, baseball had a season to remember with the "year of the pitcher" along with Detroit winning the championship.
"CARLY'S VOICE: Breaking Through Autism," by Arthur Fleishchmann with Carly Fleishmann (nf): Carly, who has severe autism, tells her story with her father along with how she is able to express herself and use modern technology, like social networking.
"A NATURAL WOMAN: A Memoir," by Carole King (nf): A memoir of the iconic singer-songwriter.
"OKLAHOMA CITY: What the Investigation Missed — and Why It Still Matters," by Andrew Gumbel and Roger G. Charles (nf): Two journalists take another look into the Oklahoma City bombing with additional documents and interviews.
"LE ROAD TRIP: A Traveler's Journal of Love and France," by Vivian Swift (nf): This illustrated guide offers a first-hand account of highs and lows on the road in France along with case histories of thriving as a traveler.
"THE GREAT DIVERGENCE: America's Growing Inequality Crisis and What We Can Do About It," by Timothy Noah (nf): Looks at the diversity and gap between the richest and poorest Americans.
"TAG, TOSS & RUN: 40 Classic Lawn Games," by Paul Tukey and Victoria Rowell, Storey Publishing, $14.95, 207 pages (nf)
The rules, strategies and interesting facts about more than 40 games designed to be played in a backyard are listed alphabetically from backyard golf to wiffle ball in this easy to use book.
- Down with love: 9 movies to celebrate Singles...
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- 'The People vs. OJ Simpson' is better than it...
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- Making music together: Couples of Utah...
- A black-and-white Valentine's Day:...
- 'Zoolander 2' is too little too late for Blue...
- 'Hail, Caesar!' struggles to hit a rhythm in...
- Down with love: 9 movies to celebrate... 3
- 'Hail, Caesar!' struggles to hit a... 2
- Chris Hicks: Academy Award rules change... 1
- Making music together: Couples of Utah... 1
- Game Review: Tumult Royale: It's tough... 0
- A black-and-white Valentine's... 0
- 'Zoolander 2' is too little too late... 0
- 'Zoolander 2': 3 points for parents 0


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Results tagged ' Ryan Howard '
Ten Players Who Need to Have A Good 2015 Season
Each and every season, there are always players with something to prove. Whether they're looking to show that they can play at a competitive level that they've never lived up to; looking to show that they can be the dominant player they once were; or simply are looking for a good year for their team to have a good year — there are numerous players that you could categorize as having very important seasons coming up.
With that said, not every player that needs a good season is on the list I put together below. I can think of a few dozen players that arguably need to post solid numbers in 2015, but I couldn't include them all, and had to make some difficult exclusions. Just the opposite, there could be a few players on my list that you don't think need a good season. Either way, this is just a list of ten players — not necessarily the "top ten" — that I feel need a good 2015 season for one reason or another:
1.) Justin Verlander
For the majority of his career, Justin Verlander has been an unbelievable pitcher. But for the 2011, 2012 seasons, he was on an entirely different planet. Going 41-13 with a 2.52 ERA over those years, and racking up a Cy Young award and MVP for his efforts in 2011, Verlander was arguably the best pitcher in baseball. Lately, however, he hasn't been the same player. Since 2013, Verlander has posted a combined 3.99 ERA over the course of 66 starts. Given, some of that may have been due to some injuries — injuries that Verlander claims are completely healed now. Now that Max Scherzer is gone, if the Tigers stand any shot at making the World Series like they play for every year, they need a dominant Justin Verlander each and every start throughout the coming regular season.
2.) Ryan Howard
Injuries have not been kind to Ryan Howard over the past three years or so. The once feared slugger, with MVP caliber numbers year after year after year, hasn't put up very much production for the Phillies in quite awhile. After hitting 58 home runs in 2006, and putting up 45+ home runs and 136+ RBI's in the three years following that historic season, Howard has failed to hit more than 23 home runs in a season since. Battling aforementioned injuries, Howard played in less than half the Phillies games in 2012 and 2013, but had a decent season last year, with 23 homers and 95 RBI's over 153 games played. But those numbers aren't good enough for the Phillies or their historically verbal fans. If he wants to regain both his stardom and the support of the fans, Ryan Howard needs a healthy, productive 2015.
3.) Jackie Bradley Jr.
Unlike the previous two players on my list, Jackie Bradley Jr. doesn't make the top ten for me because he has fallen from previously good seasons. Bradley still has something to prove — both to the Red Sox and their fans. Once one of the top prospects in all of baseball, Bradley's Gold Glove caliber defense has been shown off at the big league level, however, his ability to hit hasn't yet arrived. It needs to do so in 2015. With so much outfield depth for the Red Sox — including Mookie Betts and Rusney Castillo — it may already be too far gone for Bradley to make his all around game appear for the Red Sox. However, if he does in fact get the chance this season, he needs to show the Red Sox that he isn't just a good outfielder but an all around good baseball player.
4.) Bryce Harper
As with Jackie Bradley Jr., the 2015 season is a crucial one for Bryce Harper. While Harper hasn't underperformed, he hasn't lived up the unbelievable hype either. Cranking out just 13 home runs last season, all while battling injuries, Harper needs to have a healthy, breakout year this season. If Harper can stay healthy, and can fully tap into his power, he truly has 40 home run potential. And remember, despite the fact that he's been in the big leagues for three seasons, Harper is still just 22 years old. There's still plenty of time for him to develop into the superstar player he was coined when he was drafted first overall in 2010. If the Nationals can perform well as a whole, along with their pitching staff staying healthy, and with Bryce Harper thrown into the mix, the World Series is theirs to lose.
What can I say? Alex Rodriguez could hit 80 home runs this season and people still wouldn't like him. But while Rodriguez can't win back the majority of the fans around baseball, he still needs to have a good season, for his sake at least. Coming back from a 162-game suspension in 2014 for further performance enhancing drug use, A-Rod is heading into the season having not produced for the Yankees since 2010, when his streak of thirteen straight seasons with 30+ homers and 100+ RBI's ended. No one expects him to return to that form this year, but the Yankees need him — even if they don't want him. Their team is still a big question mark, with all the talent in the world but no guarantee things will go as planned. Alex Rodriguez needs to perform for the Yankees season to have a shot at a great one.
6.) Curtis Granderson
Curtis Granderson has never been a superstar player, but he has been a consistent outfielder over the course of his eleven year career. For six straight seasons (2007-2012), Granderson was able to post upwards of 20 home runs a season, with 2011 and 2012 being his best years by far, with 40+ homers and 100+ RBI's. Since then, however, Granderson hasn't been the same. While he hit 20 home runs last season for the Mets, he only batted .227. Though he's never been a guy that hits for a high average — an all or nothing type hitter — Granderson still needs to hone things in a bit in the coming season. The Mets are getting Matt Harvey back, and if Curtis Granderson can produce along with the rest of the team, the Mets could end up shocking some people.
7.) Melvin Upton Jr.
Formerly known as B.J. Upton, Melvin Upton Jr. definitely needs to have a good season. After losing Jason Heyward, Evan Gattis, and Melvin's brother, Justin Upton, in trades this offseason, the Braves are widely regarded as a much weaker team than they have been recently. While they could still be a playoff team, it will take production from every single player — and that includes Upton Jr. Since leaving the Rays following a 28 homer, 78 RBI 2012 season, Upton Jr. hasn't been the same, batting a combined .198 over the past two years. He needs to step up his game and bring his totals back to the former standout player he used to be. However, with reports that Melvin Upton Jr. will miss the first month or so with a foot injury, things aren't starting off too well for his 2015.
Tim Lincecum has picked up two World Series rings over the past three years (he has three rings overall), but he did little in those two seasons to produce for the Giants. After back-to-back Cy Young awards in 2008 and 2009, when Lincecum went a combined 33-12 with a 2.55 ERA, Lincecum hasn't been anywhere close to that level over the past few seasons. Since 2012, Lincecum is a combined 32-38, with a staggering 4.76 ERA. Those are certainly subpar numbers for 'The Freak'. For a guy who has gone from a dominant starter to a part time reliever, it truly is unfathomable what has gone wrong with Lincecum and his performance. With so much uncertainty, this is a make or break season in my mind for Tim Lincecum. I'll certainly be rooting for him.
9.) Joc Pederson
The only rookie on my list, and the second youngest player (Bryce Harper is six months younger than Pederson), Joc Pederson is the player that you don't really know what to expect, but needs to have a good year anyway. It's a lot of pressure on Pederson, but with the Dodgers trading away Matt Kemp to the Padres this offseason, they've now cleared the spot for phenom prospect Pederson to take over moving forward. After having the first 30 homer, 30 stolen base season in the Pacific Coast League since 1934, Pederson made his major league debut in 2014, but didn't really live up to the hype, batting just .143 and striking out 11 times in 28 at-bats (admittedly, a small sample size). Even so, there are a lot of people who still believe Joc Pederson will be able to fill Matt Kemp's shoes.
10.) Ichiro Suzuki
This is an interesting case. Ichiro Suzuki could quit right now and have Hall of Fame worthy numbers. But with him stating that he wants to continue playing for several more years, and not getting a lot of offers this past offseason, he needs to play well. Unlike last year with the Yankees, he should see more playing time with the Marlins in 2015, which should allow his always consistent numbers to be there. But with the Marlins only willing to offer him a one-year contract, he needs to prove that he is worth taking a chance on in the future. Sitting just 156 hits shy of 3,000 for his major league baseball career, Ichiro may not get there in 2015. So if he wants to reach the amazing milestone, it'll take at least one more season, which will likely come from a good season this year.
*Originally, I had Josh Hamilton on this list, but in light of his current off the field battle, I decided to replace him with Curtis Granderson. I certainly wish Josh Hamilton the best.
Home Run Derby Participants Seeing A Hitting Slump
It's been the topic of discussion for numerous years.
According to the statistics and the players themselves, a good percentage of the sluggers who take part in the annual home run derby tend to see a major plunge in their numbers to begin the second half, with the majority of those poor stats holding at that subpar level for the remainder of the season.
It's happened in the past to power hitters David Ortiz, Ryan Howard, Josh Hamilton, Chris Davis and many, many other sluggers who have taken part in the derby only to see their pre All-Star break numbers vastly overshadow the statistics they posted in the second half of the year. And once again, it's happening this season.
How much of this apparent trend is actually a pattern and how much is due to a player's career law of average just showing up (for example, a 30 home run player who hits 20 home runs before the All-star break only to fall into a "slump" and hit 10 after the break is still holding to their average) is vastly debated.
Some people claim that there is a major impact to a player's swing after they do nothing but aim for the fences when crushing balls in the home run derby. For that very reason, Ortiz and Hamilton have declined any derby invitations they've received since their initial derby appearances, with the most recent example being Jose Abreu, who didn't want to show off his power up at Target Field this year for fear that it would mess up his swing.
But that's just one side of the coin.
On the other side, people seem to believe that the second half numbers a player produces after a derby are just a player returning to the previously mentioned law of averages — after all, every player goes through a slump at some point every season. However, now that two weeks have passed since the derby, with multiple players who were in the 2014 home run derby currently struggling, I'd have to go with the theory that a player's swing is affected by the derby, at least in the short term.
Justin Morneau was a participant in this year's derby, but he's yet to play in any games since that point, so there are no numbers to go by, though he was batting .312 with 13 home runs and 60 runs driven in before the derby. Fellow derby and Rockies teammate, Troy Tulowitzki, is also currently injured, however he took part in two games before hitting the disabled list, recording no hits in 5 at-bats, after batting .345 with 21 homers and 52 RBI's over the first half.
While there are no true numbers to look at for either Morneau or Tulowitzki, and thus no way to know how each player would be performing, a couple of injuries after the derby isn't exactly a positive thing.
Of the players who aren't on the disabled list at the moment, Brian Dozier has seen the biggest fall in numbers of them all. After getting off to a career season to get the year started, with 18 homers and 45 RBI's, the lone hometown player to take part in the derby is now batting a mere .125 with two RBI's on a single home run since the second half began. Also joining him with a .100's batting average since the derby is Todd Frazier (batting .154), who has hit just one home run after slugging 19 throughout the first half.
Adam Jones and Giancarlo Stanton are also sharing in the same fate, with both batting in the .200's since the All-Star break.
Jones posted a .301 batting average with 16 home runs and 54 RBI's to begin the year, and despite having fallen a bit in batting average since, he's launched 3 homers and amassed 10 RBI's since the break — not jaw dropping, but also not terrible.
Stanton on the other hand is doing much worse, having slugged just two home runs since the derby — a derby he lost, even though he was the heavy favorite to win — despite hitting 21 before the All-Star break.
But as has held true throughout derby history, not all players are seeing a slump.
Although he hasn't found his power swing since the derby, Yasiel Puig is still hitting for average, having batted .333 in the past couple of weeks. However, with no home runs and just two runs batted in, after blasting 12 before the break and driving in 52 runs, he's still not the Puig everyone has come to know.
Jose Bautista has fared fairly well since the derby, batting .333 with 3 home runs and 7 RBI's, after batting .292 with 17 homers and 54 RBI's in the first half, which holds fairly steady with his average pace over his career. Hitting .324 since the derby, Josh Donaldson is also holding his own, having hit a couple of homers in the second half after batting .238 with 20 homers over the first portion of the season.
The player who seems to have experienced the least amount of problems with his swing is the winner of the derby, Yoenis Cespedes, who actually looks to have improved. After batting just .254 to begin the year, Cespedes is batting .324 over the course of nearly 40 at-bats since the derby (admittedly, a small sample size). In addition, Cespedes has slugged 3 homers and driven in 10 runs in this second half, however, seeing an increase in stats after winning the home run derby in 2013, it would seem that Yoenis Cespedes is the exception to the overall derby rule.
Ten Players Who Need to Have A Good 2014 Season
Spring Training is well underway, and many players are beginning to find their grooves that they hope will carry over into the coming regular season. With just over three weeks until Opening Day, on March 31st, there's not too much time remaining for players who struggled last season to get things back on track for this year. With that said, some players certainly need to have a good year more than others.
While every player, obviously, wants to have a good, healthy season, there are numerous players who pretty much have to produce a good 2014 for one reason or another — whether it's personal reasons, statistical reasons, or for team success as a whole. Although there are more players than those in my list below, here are the top ten players (in no particular order) that I feel need to have a really good 2014 season:
1.) Albert Pujols
After recording twelve straight seasons of 30 or more home runs (all but one of which included 100+ RBI's) Albert Pujols faced the first bit of adversity of his career in 2013. Dealing with a nagging foot injury, Pujols only managed to post 17 home runs and 64 RBI's, along with a .258 batting average — absolutely terrible by his standards — in 99 games played. With the down year coming as a shock to many people, especially after the acquisition of him led many to predict playoff pushes for the Angels, there will be many eyes on Pujols from his very first at-bat of the season to see if he can bounce back. I personally feel that if Pujols is healthy, the numbers will be there, and he will be a top candidate for American League comeback player of the year, but I guess we'll have to wait and see.
2.) Ryan Braun
In January of 2013, a list was made public by the biogenesis clinic in Miami, Florida, connecting numerous players to performance enhancing drugs, including Ryan Braun. After being connected to PED's back in 2011, the list raised many red flags, but Braun denied any drug use, yet again. But finally, after a 65-game suspension by Major League Baseball, Braun came clean and admitted to having used PED's, upsetting many people around the league. Therefore, unlike anyone else on my list, Braun (who had a good season, batting .298 with 9 homers and 38 RBI's in 61 games) needs to have a good 2014 more for his personal image rather than his talent level image. Everyone knows he's a great player, but it will take some time for fans to get over Braun's consistent denial of PED use — and a great season would certainly help with that.
3.) Ryan Howard
Battling injuries over the course of the past two seasons, Ryan Howard needs to have a bounce back year for him to once again be considered the major power threat that he once was. Playing in only 80 games in 2013, Howard batted a mere .266 with 11 home runs and 43 RBI's. Considering the fact that Howard hit 33 home runs just two years prior, making it the sixth 30+ home run season of his career, the Phillies' former star first baseman really needs to show signs of his former self this season. If Howard can perform anywhere near his previous level by staying healthy and putting many a ball into the outfield seats, not only could he very well win the 2014 National League comeback player of the year award, but the Phillies could have a real shot at having a memorable year.
4.) Derek Jeter
Announcing that 2014 would be his final season playing Major League Baseball last month, Derek Jeter needs to have a good final season to top off an already incredible career. In 2013, Jeter struggled with injury after injury, managing to play in only 17 games, and posting a .190 batting average, to go along with a single homer and 7 runs batted in. After accumulating over 3,300 hits in the big leagues over the course of his career, Jeter doesn't need to have a good final season to be remembered as one of the best players of all-time — he's already on that list for many people — but rather to finish out his career in Jeter fashion, going out on top of his game. I truly hope he can have a great 2014 season, and I feel he will do just that.
When David Price won the 2012 American League Cy Young award, recording 20 wins and posting a 2.56 ERA, many (myself included) felt he had a good chance at doing the same again last season. But instead, Price was faced with a midseason injury that caused his numbers to take a tumble. Posting a win-loss record of 10-8 with a 3.33 ERA — not too terrible, but somewhat disappointing for him — Price needs to bounce back in 2014 for both his sake and the sake of the Rays. Price truly can be the key for the Rays, who always seem to be on the brink of playoff baseball every season. With an improved American League East division for the coming year, Price's season could be the difference maker for if the Rays are able to make the postseason or not.
6.) B.J. Upton
Arguably the biggest disappointment of the 2013 season, batting .184 with just 9 home runs and 26 RBI's after a 2012 season of 28 homers and 78 runs driven in, B.J. Upton has to have a good season this year for him not to be considered a trade bust by the Braves. The Braves managed to win their division last season by a rather large margin without much production from Upton, and if they can get Upton back to his former self, the Braves could have an even better year. It will be interesting to see how B.J. Upton does in the coming year with so much negative criticism surrounding him from the 2013 season. If he can have another good season, the down year he experience will be a forgotten aspect of the past.
7.) Stephen Strasburg
There are some players that are tagged with a major amount of hype from their first appearance in the big leagues, and Stephen Strasburg is one of them. While he hasn't disappointed for the most part, going 8-9 with a 3.00 ERA last season, Strasburg also hasn't managed to blow everyone away and completely dominate like many believe he can. It's been reported that Strasburg has added a new pitch to his arsenal and is throwing better than ever, and that could mean good things for both him and the Nationals. If Strasburg can find a way to tally even ten more wins than he did this past year, the Nat's could find themselves in the running for the National League East division title, assuming everything else goes right for the rest of the team.
Having the potential to be an All-Star third baseman season after season, Mike Moustakas has yet to post an exceptional season at the major league level. Batting only .233, with 12 homers and 42 RBI's last season, Moustakas needs to have a good season this year for him to be seen as the above average player he can be moving forward. The Royals still have several holes in their lineup, but Moustakas performing well each year would go a long way in helping them move back into contention. He's still fairly young, at just 25 years old, and therefore has time left to live out his former hype, but Moustakas could use a strong statistical season to prove to many that he's one of the top third baseman in the game of baseball today.
9.) Matt Kemp
Although he's still not fully healthy, Matt Kemp is already on the radar of many people who think he will have a good 2014 season. The only question mark being his health, playing in only 73 games last year. If healthy, as with many players on this list, the numbers will be there, as Kemp is one of the premier talents in the game today, possessing 40 home run, 40 stolen base ability (coming one home run shy of doing just that in 2011, when he placed second in MVP voting). Although there is great depth in the Dodgers' current outfield, which includes players such as Carl Crawford, Andre Ethier and Yasiel Puig, if Kemp can show signs that he's healthy, he will certainly get plenty of playing time in the coming season. He's too good of a player to count out.
10.) Tim Lincecum
Once a Cy Young caliber pitcher, having won back-to-back awards in 2008 and 2009, Tim Lincecum has really fallen off as of late. Each of the past two seasons, Lincecum has posted an ERA over 4.00, and in addition had losing records. While the win-loss record isn't the most important thing when evaluating a pitcher's season, an ERA anywhere above 3.50 usually means they had a disappointing year. But with the talent that Lincecum has shown in the past, I'm not giving up on a turnaround just yet. He just really needs to have a good 2014 season — perhaps more than most of the players on this list — for him to become 'The Freak' pitcher he once was considered. I truly hope he can, because when Lincecum is on, he's one of the most fun pitchers to watch in all of baseball.
There are a few players who need to have a good 2014 season who just barely missed my above list because their stats were slightly too good. One of those being Josh Hamilton, who was a major disappointment after signing with the Angles, but when you check the stats, he actually had a decent year, hitting 21 home runs and driving in 79 runs. Another example of that being Yoenis Cespedes, who had a down year average wise, hitting just .240, but posted 26 homers and 80 RBI's. Not too bad of a season for most players.
Joining those two on the list of just misses are Giancarlo Stanton, who was injured in 2013 but still managed to hit 24 home runs and amass 62 RBI's, along with Dan Uggla, whose .179 batting included 22 homers and 55 RBI's, which really isn't all that terrible. While all the players listed under the just missed category had down seasons by their standards, they managed to have somewhat decent years as far as the major league average goes. Even so, they could each use a good 2014 season to prove what they're capable of.
Which player needs to have a good 2014 season the most? Leave a comment below.
Baseball Returns With Spring Training Action
Although Spring Training baseball isn't as meaningful as the regular season, and despite the fact that most of the stars on the team are removed by the fifth inning, this time of year is exciting, nonetheless, for baseball fans all around the country.
The first regular season games of the year aren't set to take place for another few weeks, with the opening-series being played in Australia on March 22nd, but even so, today marked the first official professional baseball games of the year.
And therefore, things are finally starting to get going again.
The Phillies, Blue Jays, Pirates, Yankees, Tigers, Braves, Dodgers, D-backs, Athletics, Giants, Reds and Indians all saw action on Wednesday, with the remaining teams playing their first games of the year against another big league organization over the course of the next two days. While things are still fairly early, several players are already looking promising.
One of the biggest question marks for the 2014 season, after a couple of injured years, is Ryan Howard. Once one of the games biggest power threats, Howard hasn't been himself as of late. But out of the gate so far this spring, including practice games, Howard looks healthy and like he's seeing the ball really well.
Jose Bautista is another player who has had injuries hurt his stats each of the past two seasons but is looking good to bounce back this year. In his first at-bat of Wednesday's game, Bautista crushed a ball completely out of the ballpark off the Phillies' Roberto Hernandez. If the Blue Jays have Bautista going, he could help lead them higher up in the rankings than they finished last year.
As far as teams go, the Athletics look as though they could pick up where they left off in 2013, once their season begins on March 31st. They did extremely well against the Giants in their first matchup of the year, and with the additions they made in the offseason, they should really make some noise in the talented American League West.
It's far too early to say for sure whether or not these trends will continue, with there still a being ton of baseball left to be played before things begin to count towards the standings. But, as stated earlier, things are looking promising for an exciting 2014 season.
Fastest & Slowest Starts to the 2013 MLB Season
We're just over a week into the 2013 MLB regular season, and I wanted to post a blog, just like last year, on the fastest and slowest starts to the season for both entire teams and individual players. While it's a small sample size, the list gives you an idea of what's been taking place so far this season. Some of the players and teams are performing nearly as well as expected, but others are putting on performances that I never would've predicted them to begin the season with.
1) Braves (6-1)
2) Diamondbacks (5-2)
3) Rockies (5-2)
4) Red Sox (5-2)
5) Athletics (5-2)
6) Rangers (5-2)
7) Reds (5-2)
8) Mets (5-2)
The Braves currently lead all of baseball with a win percentage of .857. Justin Upton has been making a major impact, hitting six home runs in the first seven games, and I fully expected the Braves to have a season long performance like the one they're currently starting out with. The Diamondbacks, Rockies, Red Sox and Mets are all surprising me, so far, as I expected them to all have poor seasons, and while it's still very early, at the moment, they're making things interesting. As far as the Athletics, Rangers and Reds go, it's not a shock that they're doing so well. Though I thought the Rangers would have a bit of a struggle this season, without Josh Hamilton, they seem to be doing just fine. It should be interesting to see if they can keep it up.
1) Adam Jones (.500)
2) Jed Lowrie (.500)
3) Carlos Santana (.500)
4) Michael Cuddyer (.478)
5) Carl Crawford (.450)
6) Jean Segura (.450)
*Minimum of 20 AB's
Adam Jones is the only player on the list of fastest start players that I'm not surprised with. Having recorded a 32 homer, 82 RBI season, in 2012, Jones is in the prime of his career, and is set to have another fantastic season. For Jed Lowrie, Carlos Santana, Michael Cuddyer, Carl Crawford and Jean Segura, they better enjoy the hot start while it lasts, because I don't see any of them having an all that spectacular year. But as with anything in baseball, there's always the chance for me to be proven wrong.
1) Astros (1-6)
2) Marlins (1-6)
3) Padres (1-5)
4) Pirates (2-5)
5) Brewers (2-5)
6) Phillies (2-5)
7) Cubs (2-5)
After beating the Rangers, 8-2, on Opening Night, the Astros have done nothing but go down hill, ever since. With 155 games left to play, and just 94 losses away from 100, it's likely the Astros' season will end with yet another year of 100+ losses. The Marlins, Padres and Pirates are all teams that have the potential to win now, but it's likely to be a year or two before they start to become big time contenders in their divisions. The Brewers and Phillies are the only teams that surprise me, somewhat, on this list, but they just haven't performed well so far this year. And as for the Cubs, they're just being themselves; destined to make it 105 seasons without a World Series title.
1) Jeff Keppinger (.048)
2) Ryan Hanigan (.050)
3) Aaron Hicks (.067)
4) Pedro Alvarez (.080)
5) Neil Walker (.083)
*Minimum of 20 AB's
No one on this list surprises me, other than Neil Walker. Walker is arguably the best player on the list, but he hasn't been able to find his groove so far this season. I look for him to get things going, however, and record another season like he has the past few years–10-15 homers and 65-80 RBI's, with a high 200's batting average. For Jeff Keppinger, Ryan Hanigan, Aaron Hicks and Pedro Alvarez, it will be interesting to see if they get their acts together, or if this is a sign of things to come for them this season, as things can certainly only go up.
Keep in mind, while those are the players and teams with the fastest and slowest starts to the season, there's still a lot of baseball left to be played, and anything can happen. Only time will tell if the current trends will last; that's why they play 162 games.


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Publications (3)1.78 Total impact
Article: [Significance of multidrug resistance gene-associated proteins in the postoperative adjuvant chemotherapy for gastric carcinoma and the prognosis.][Show abstract] [Hide abstract]
ABSTRACT: To investigate the expression of multidrug resistance (MDR) gene-associated proteins (MRP) in gastric carcinoma, and their effects on the postoperative adjuvant chemotherapy and the prognosis of patients. The expressions of ToPo II, MRP, GST-pi in 99 patients with gastric carcinoma were detected by immunohistochemistry. The expression and its relationship to the pathological data were analyzed. The positive expression of MRP and GST-pi, and the negative expression of ToPo II were considered as risk factors. Patients were divided into two groups: a high risk drug-resistant group (2-3 risk factors) and the low risk drug-resistant group (0-1 risk factors). Postoperative recurrence, survival rate, and efficacy of adjuvant chemotherapy were compared between two groups. The positive rate of ToPo II was 74.7%, and the expression was associated with types and differentiation of the tumor. The positive rate of GST-pi was 49.5%, and the expression was related to the gender and the differentiation. The positive rate of MRP was 40.4%, and there was no relationship between the MRP expression and the pathological finding. There were no significant differences in the recurrence, time to recurrence, and the 5-year survival rate between the positive and negative group of the three proteins (P>0.05). Recurrence was found in 25 cases(55.6%) in the high risk drug-resistant group and the mean time to recurrence was (15.2+/-8.1) months. The time to recurrence was shorter in the low risk drug-resistant group [(21.3+/-11.1) months, P<0.05] , but there was no significant difference in the recurrence rate between two groups (P>0.05). The 5-year survival rate of the high risk drug-resistant group and the low risk drug-resistant group was 44.4% and 55.6% (P>0.05). The 5-year survival rates of patients with or without chemotherapy in the high risk drug-resistant group were 45.8% and 42.9% (P>0.05). The 5-year survival rates of patients with or without chemotherapy in the low risk drug-resistant group were 70.4% and 40.7%. The survival rate of patients with chemotherapy was higher than that of the patients without chemotherapy (P<0.05). The expression of ToPo II, MRP and GST-pi is associated with the efficacy of postoperative adjuvant chemotherapy. Chemotherapy appears to be more beneficial to patients with low risk drug-resistance.
Article: [Relationship between the protein expression of P53, c-erbB-2, vascular endothelial growth factor and CD44 and the survival rates of stage II( colorectal cancer patients without radiochemotherapy after radical resection].[Show abstract] [Hide abstract]
ABSTRACT: To investigate the relation between protein expression of 4 genes [P53,c-erbB-2,vascular endothelial factors(VEGF) and CD44]and survival rate in stage II( colorectal cancer(CRC) patients without radiochemotherapy after radical resection. One hundred and fifty-nine cases of stage II(CRC without radiochemotherapy were enrolled in this study. The clinicopathological date and 5-year follow-up data were reviewed. Streptavidin-peroxidase immunohistochemical technique was used to detect the expression of P53, c-erbB-2, VEGF and CD44 in formalin-fixed, paraffin embedded sections of CRC tissues from above 159 patients. The 5-year survival rate was 82.4%. The rates of positive expression of P53, c-erbB-2, VEGF and CD44 were 58.5%(93/159), 26.4%(42/159), 57.9%(92/159) and 40.0%(54/159) respectively. The 5-year survival rates of positive expression patients were not significantly different with those of negative expression. chi(2) analysis showed that the positive expressions of 4 genes had no relationships with the prognosis. The expression of 4 gene proteins has no relationship with the prognosis of stage II( CRC patients without radiochemotherapy after radical resection.
Article: Zhong H, Zhang Y, Ma S, Ying JE, Yang Y, Yong D, Hang X, Sun Q, Zhong B, Wang DDocetaxel plus oxaliplatin (DOCOX) as a second-line treatment after failure of fluoropyrimidine and platinum in Chinese patients with advanced gastric cancer. Anticancer Drugs 19(10): 1013-1018[Show abstract] [Hide abstract]
ABSTRACT: The fluoropyrimidine and platinum-based combination chemotherapy is now widely used as first-line therapy for advanced gastric cancer (AGC). Unfortunately, about half of all patients do not respond to the current first-line chemotherapy and furthermore, most patients who achieve response to first-line chemotherapy eventually experience disease progression. Although there is a need for effective salvage treatment after the failure of first-line chemotherapy, data on the safety and efficacy of second-line treatment in AGC is limited. The current study evaluated an experimental combination regimen of docetaxel (60 mg/m) as an intravenous infusion of less than 1 h, followed by oxaliplatin (130 mg/m) intravenously for less than 2 h. Both drugs were administered on day 1 of a 21-day cycle, in pretreated Chinese patients with AGC. The trial enrolled 48 patients of whom 46 (95.8%) were assessable for response. The median time to progression was 4.4 months (95% confidence interval (CI): 3.4-5.4 months) and the median overall survival was 7.2 months (95% CI: 6.6-12.1 months). Partial response was confirmed in 11 of 48 cases (22.9%; 95% CI: 10.9-34.9%) and no complete responses were seen. Significant hematologic toxicity was noted with grade 3 and grade 4 neutropenia occurring in 21.7 and 4.3% of patients, respectively, as well as grade 3 thrombocytopenia occurring in 4.3% of patients. Grade 3 febrile neutropenia occurred in 6.5% of the patients. There were no treatment-related deaths during on the study. In summary, docetaxel and oxaliplatin have modest activity with predictable hematologic toxicity when given as salvage therapy for Chinese patients treated earlier for AGC. Given the short duration of response more focus should be given to newer biologic agents and triplet regimens.
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Zhejiang Cancer HospitalHang-hsien, Zhejiang Sheng, China


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We have just published the revised Visual Studio Team Foundation Server 2010 Capacity Planning poster on both the Visual Studio 2010 Quick Reference Guidance and Visual Studio 2010 and Team Foundation Server 2010 Virtualization Guidance projects. A special thanks to Mario Rodriguez and the Rangers for their input and reviewing of the numerous iterations of this poster.
The following changes have been made:
You can find the Rangers solutions at VSTS Rangers Home or find a list of the latest Rangers solutions on my blog, in the navigation pane under "News".


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