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12/24/2012 (3 years ago)
Catholic Online (www.catholic.org)
She lived in His presence. She still does. In every encounter, she surrendered to love and was changed. She was a woman prepared by God and continually surrendered to His love. This is the meaning of Mary. She is our model as well as our mother.
Catholic Online (www.catholic.org)
12/24/2012 (3 years ago)
Published in Living Faith
Keywords: Mary, Marian, Ave Maria, Rosary, Hail Holy Queen, Fiat, Magnificat, Deacon Keith Fournier
CHESAPEAKE, VA (Catholic Online) - "At the announcement that she would give birth to "the Son of the Most High" without knowing man, by the power of the Holy Spirit, Mary responded with the obedience of faith, certain that "with God nothing will be impossible": "Behold, I am the handmaid of the Lord; let it be [done] to me according to your word." Thus, giving her consent to God's word, Mary becomes the mother of Jesus. Espousing the divine will for salvation wholeheartedly, without a single sin to restrain her, she gave herself entirely to the person and to the work of her Son; she did so in order to serve the mystery of redemption with him and dependent on him, by God's grace".
"As St. Irenaeus says, "Being obedient she became the cause of salvation for herself and for the whole human race." Hence not a few of the early Fathers gladly assert: "The knot of Eve's disobedience was untied by Mary's obedience: what the virgin Eve bound through her disbelief, Mary loosened by her faith." Comparing her with Eve, they call Mary "the Mother of the living" and frequently claim: "Death through Eve, life through Mary." (CCC #494)
There are very few records of Mary's explicit words in the texts of the New Testament of the Bible. However, there is no lack of her presence at the most significant events in the life, ministry, death and resurrection of Jesus Christ and therefore in the great events of salvation history. She always encountered God - in profound ways - from the beginning to the end of her life. She lived in His presence. She still does. In every encounter, she surrendered to love and was changed. She was a woman prepared by God and continually surrendered to His love. This is the meaning of Mary. She is our model as well as our mother.
Mary was there at the Incarnation, Birth, Crucifixion, and Resurrection of the One whom Christians proclaim is God Incarnate, Jesus Christ. She was there throughout what are often called the "hidden years" in His life at Nazareth where ordinary work was ennobled and childrearing forever changed because of His participation. His disciples spent three years with Him, during His "public ministry", but Mary spent thirty three years!
We should remember and reflect on the truth that in the earthly life of the Redeemer, every word he uttered - at every age and stage - and every act he undertook was redemptive, revealing as it does the very life of God and the mystery of heaven touching earth. Because of that, every moment of His presence among us reveals the deeper purpose of our own lives when they are lived entirely for Him.
Mary was there in all those pregnant moments of His complete thirty three year earthly mission of love. His redemptive presence forever changed the history of the world and can do so in our own personal histories if we learn how to surrender to His invitation to love and choose to live as she did. The mission of the Redeemer continues now for all who have the eyes to see His presence still walking and working among us; and the ears to hear His loving words still being spoken amidst the cacophony of our daily lives. Mary did.
His presence forever changed the world that we are all living in. We are welcomed into a new relationship with Him and therefore with this world that He still loves, if we invite His redemptive presence into our lives, co-operate with grace in order to change ourselves and allow ourselves to be prepared from His coming. Every waking moment can now be filled with the invitation of grace, if we learn to discover their deeper meaning and make them our own. If we learn to live our entire life as, an invitation to love, an encounter with the God of love, as Mary did, we will find our lives transformed by the Son whom she bore for the whole world.
She was the first evangelizer and the first disciple of her own Son Jesus. She gave the first Gospel testimony to her cousin, Elizabeth, without words, as the Redeemer in her womb drew the child in her womb, John the Baptizer to Himself. He did so from the Throne he had established in Mary's womb. Jesus, Love Incarnate, drew John from the very first home of the whole human race, a mother's womb. At the beginning of that missionary encounter, Elizabeth greeted Mary with profound humility, saying "who am I that the mother of my Lord should come to me?" Then the son in her own womb became the first convert "in utero" as he leapt in praise of the Maker of the Universe, taken residence in Mary's womb.
John the Baptizer, the last Prophet of Old Testament and first of the New, was prepared in a womb - and drawn by this amazing grace - without a word being spoken, through Mary's witness of surrendered love. This event, traditionally called "The Visitation," recorded in the Gospel of St. Luke (Luke l: 39-45), is meant to continue in our lives as we carry Jesus forward in time. It can through the witness of our surrendered lives of love.
In the Biblical account, this encounter immediately follows the visit of the Angel Gabriel to Mary (Luke 16:38) and is a fruit of her humble obedient response to the word of God which she was most certainly attuned to hearing. That response was not a one time reaction. It was the fruit borne from a life of surrendered love and it stretched forward to characterize and inform her entire life.
Mary was there at the Wedding Feast at Cana in Galilee, when the first of the Lord's "signs" occurred - in a response to and as a fruit of - her intercession. It was there she gave that sage and still relevant advice to all those in attendance at that wedding and to all who throughout human history seek to follow her Son, "Do whatever He tells you". She still invites that kind of response through the testimony of her simple, surrendered life which continues to witness throughout human history to all men and women who choose to follow her Son, the Redeemer of the world.
She was there on the great day of Pentecost, the birthday of the Church, and witnessed the extraordinary clothing with the Holy Spirit that transformed and empowered the early disciples. That same Holy Spirit had inspired her own unique missionary vocation. Mary understood this work of the Holy Spirit unlike anyone in history. She had been clothed in that wonderful gift when she was first visited by the angel and "overshadowed." It empowered her to live her whole life in complete surrender to God's will and to thereby prefigure the mission of the entire Christian community throughout history.
Mary understood all of this because she was a woman in love -with God. Mary was a woman of prayer, an ongoing conversation and intimate communion with God. We are invited into her prayer because we are invited into that same relationship with God. Understanding and living the Prayer of Mary is about living a life of surrendered love. It is about being- more than about doing. It is about response- more than initiation. It is about encountering God relationally, personally and intimately. It is about a receiving, giving, receiving, giving..and thus becoming a person for the Lord and in Him for others. It is about offering the "Fiat" of a surrendered life. Mary's "Fiat" ("let it be done"), freely given in response to the visitation from the messenger of heaven, the angel, provides a pattern of prayer and a way to live for every follower of her Son.
In the biblical account her Fiat issues forth into the very real fruit of her praise, her "Magnificat." This song is recorded in the sacred text of the New Testament of the Bible and begins with the words" My soul doth magnify the Lord." This hymn of praise has been memorialized in that ancient, beautiful, biblically based prayer that the Christian tradition refers to as "The Magnificat" (Luke 1:46-55). This prayer contains the very essence of the Christian faith, the Christian life, and for those with eyes to see, ears to hear and hearts to understand, reveals the very meaning of human existence. We were made to give ourselves away in love because we were made for God.
The "Fiat" is more than a prayer and the "Magnificat" more than a hymn of praise. Together they constitute a lesson book, a guide, and a road for this journey that we are all called to walk. Our daily life, so very real and human, with all of its blessings and all of it's pain, can be packed with meaning, purpose and destiny; if we have the eyes to see, ears to hear and hearts' to respond with the kind of voluntary surrender that was so beautifully expressed by Mary, the Virgin of Nazareth. That response to the gift of God reveals the heart of true faith.
This lesson book is desperately needed by Christians, indeed all people of good will, in this age so characterized by pride, arrogance of power and grandiosity. The pattern of that prayer and the melody of that song reveal the pattern of Mary's entire life and the score of what our own is meant to become. It follows along a trajectory of surrendered love. It begins with Gods gift and invitation, proceeds to a response, leads to praise and is intended to bear the fruit of a meaningful life, pregnant with the promise of redemption.
It is this pattern that we must make our own if we are to comprehend and live its relevance in our own lives. When we learn to walk in "Mary's way", which is the way of her Son and Savior, we will find the meaning of life itself because we choose through love to give "our" lives away in love, to the One is Love. Mary said "Yes" to the invitation to love and she humbled herself. She confronted her own fears and she entered into a new way of living. All of this was in continued response to an original invitation of love, a gift, initiated by a loving God.
Her simple response of "yes" overflowed into her "Magnificat" of praise. Through this response, she assumed a life's posture of receiving and giving, she became a fruitful woman, a "God-bearer" or "Mother of God" (which in Greek is Theo-tokos). She brought forth the Word of God and "the Word became flesh and dwelt among us". Her "Yes", her humble surrender, bore the fruit of her "Magnificat" which bore the fruit of the Word, which was spoken and birthed through her. This is a kind of trajectory of love. It provides a prototype of the vocation of every human person who says "Yes" to God and learns to bear the fruit of surrendered love. Her "Yes" touches the inner core of the meaning of life for all men and women who are children of the one Creator. We were made to give ourselves away to the Lord and to others.
God is not an "add on" to our life. Rather, He is its source and its summit. Authentic and fruitful spirituality is "inside out" rather than "outside in." There is a way, a pattern that all men and women are invited into - not just once, but daily. This is the way of surrendered love. Mary's surrender reveals the deeper meaning of every human life and is the true path to authentic peace. It is the portal of the mystery of meaning itself. It is what Christian Scripture calls the "more excellent way" (1 Cor. 12), the way of love.
Mary understood and walked this way with extraordinary humility. Is it any wonder that the early Christians painted her image in the catacombs during their moments of fear, persecution and doubt? They found great inspiration from this little woman of great faith. In her yes they came to understand that ordinary people can change human history. They were inspired to add their own yes, their own fiat to hers. Is it any wonder that the writings of the early fathers of the Christian Church are also replete with reflections on this woman who said so little verbally in the biblical text? That is because it is not about an abundance of our words but rather our receptivity to the Word.
Justin Martyr and many other early Christian apologists found in her "fiat", her obedient "yes" to the angel, the undoing of the "no-I will not serve" uttered in rebellion by the first woman Eve. They called Mary "The Second Eve", the mother of a new creation, because she said "Yes" and in her womb carried the One whom the biblical authors would call the "New Adam." Jesus Christ was born from her as the first born of a new race of men and women who would themselves come to find a new birth through His life, death and Resurrection through saying "Yes" to him in both word and deed.
That same Redeemer now comes to reside within, and live through, all of those who respond to the invitation of Love like Mary did. All who are prepared and who surrender. Mary's choice, her response to the invitation of a God who always respects human freedom, is a singularly extraordinary event in all of human history. However, it is meant to be much more. It is meant to be an invitation to each one of us to explore our own personal histories and to write them anew in Him.
By Andrea Gagliarducci, CNA/EWTN News
The first, historic meeting between a Pope and a Patriarch of the Russian Orthodox Church does not come from nowhere. Both the Russian Orthodox Patriarchate and the Holy See have been working on such an event for decades. Vatican City (CNA/EWTN News) - In at ... continue reading
By Kenya Sinclair (CALIFORNIA NETWORK)
The Vatican recently announced the historic meeting between Pope Francis and the head of the Russian Orthodox Church, Patriarch Kirill. LOS ANGELES, CA (Catholic Online) - The meeting is set for Friday and will be the first time the heads of the Catholic and Russian ... continue reading
By Kenya Sinclair (CALIFORNIA NETWORK)
The oldest surviving copy of the Old Testament was officially recognized as a world treasure by the United Nations Educations, Scientific and Cultural Organization (UNESCO). LOS ANGELES, CA (Catholic Online) - The Aleppo Codex is the oldest surviving copy of the Hebrew ... continue reading
By Catholic Online (CALIFORNIA NETWORK)
Those who commit "reserved sins," transgressions that are deemed especially egregious by the Catholic Church, will have another chance this Jubilee Year. Those who have committed such sins previously only pardonable by the Pope may now seek out the 1,142 ... continue reading
By Kenya Sinclair (CALIFORNIA NETWORK)
Christians stand together outside the U.S. Supreme Court to call other believers to pray the pro-life law passes. LOS ANGELES, CA (Catholic Online) - While the Supreme Court considers a Texas pro-life law, Texas Loves Life calls for Christians to pray for the fates of ... continue reading
By Elise Harris, CNA/EWTN News
For Pope Francis, mercy is not just spiritual, but is something that ought to be expressed in concrete acts of service and in sharing one's goods with the poor, which was a key tradition during Jubilee years throughout Scripture. Vatican City (CNA/EWTN News) - ... continue reading
By Kenya Sinclair (CALIFORNIA NETWORK)
Members of the Praise and Worship Club, composed of NASA employees, were shocked to receive a notice from NASA ordering they cease to include Jesus' name in their religious e-mails. LOS ANGELES, CA (Catholic Online) - The use of Jesus' name came up in May 2015, when ... continue reading
By Catholic Online (NEWS CONSORTIUM)
Catholic Online is conducting a global survey on Ash Wednesday practices. Each reader is asked to participate once. The survey will take less than a minute to complete. The results of the survey will help Catholic Online determine how best to serve your needs in the ... continue reading
By Kenya Sinclair (CALIFORNIA NETWORK)
Despite the Catholic Church openly saying Santa Muerte is not recognized as a saint, the death saint continues to spread in popularity among Mexican citizens. LOS ANGELES, CA (Catholic Online) - "Santa Muerte is an absurdity," Cardinal Norberto Rivera, Mexico's ... continue reading
By Kenya Sinclair (CALIFORNIA NETWORK)
Televangelist Morris Cerullo has been attempting to build a Bible-themed luxury resort for the past few years - and now there is only one more hurdle to jump. LOS ANGELES, CA (Catholic Online) - After purchasing a foreclosed Mission Valley hotel, Cerullo's plans for ... continue reading


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Hi Ladies,.
I finally got my BFP yesterday. I am so excited but cautious because I got a faint line and I have been testing everday making sure it does't disappear. I had a chemical pregnancy last year.PLEASE BABY STICK!!
I hope I can join in and share this journey with you wonderful ladies.

subset: commoncrawl


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Combo Discount:
Racing heart
1 person found the following review helpful
Posted by Reviewer1580563 on Jan 31, 2008
I can't really speak to its effectiveness because I couldn't take it long enough to tell. It really made my heart race, even with taking b-complex.
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text: Warning: Declaration of vB_ProfileBlock_vBSEOLikes::block_is_enabled() should be compatible with that of vB_ProfileBlock::block_is_enabled() in Unknown on line 0 View Profile: OdysseyPC - MP3Car.com Register Help Remember Me? Blog Technology Events Products and Technology How To Videos mp3Car News Product Reviews Store Sales Write a blog Auto App Mart Store Shop Store Sales Contact Store Survey New Vendor Signup Forum Forum Home Contact Projects Admin Mod Log In Enterprise Free Phone Consultation What We Do Partners Contact About Us History Team Press Release Contact Resources wiki FAQ Videos How to Use the Forums CarPC 101 Videos Videos mp3Car Today's Posts Community Groups Albums Member List Forum Actions Mark Forums Read Quick Links View Site Leaders New Posts Live Forum Rules Advanced Search Member List OdysseyPC under nav bar OdysseyPC Constant Bitrate Array Find latest posts Find latest started threads View Articles View Blog Entries Likes Received (0) Likes Given (0) Mini Statistics Join Date 10-04-2003 Last Activity 06-15-2007 07:28 AM Avatar Recent Visitors The last 3 visitor(s) to this page were: drug_online, Pills_online, StephJones This page has had 988 visits Tab Content About Me My PhotosLikes Received About OdysseyPC Basic Information Date of Birth January 12, 1982 (34) About OdysseyPC Car Details: '02 VX Commodore Series II Executive Location: ACT, Australia Interests: Multelemediaphotimeshiftingtunerpc-ing, Circuit Design, Programming Occupation: Electrical/Electronics Engineer Signature Caputer Mk. II '02 VX Holden Commodore Series II Executive MII12000, 512MB RAM, 60GB HDD (5400rpm), 16X DVD, TS200V Morex 60W DC-DC, Custom S/SDC OS/Software: Developing... Statistics Total Posts Total Posts 114 Posts Per Day 0.03 General Information Last Activity 06-15-2007 07:28 AM Join Date 10-04-2003 View All Images My Photos No image hosted 0 Likes -- Default Style -- Default Mobile Style Contact Us mp3Car Forums Archive Top All times are GMT -5. The time now is 02:29 PM. Powered by vBulletin® Version 4.2.2 Copyright © 2016 vBulletin Solutions, Inc. All rights reserved. Content Relevant URLs by vBSEO 3.6.0 PL2 Copyright © 1999 - 2011 Mp3Car.com Inc.


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Mass Destruction by niqhtliqhtsWatch
©2013-2016 niqhtliqhts
New-ish improved kind of style..? Nahh. Everything's the same. I just improved on it a bit.
This is a gift for =Fluffy-pawed! Because I love space and all of that goodness.
Only for =Fluffy-pawed's use!
(I'm sort of back from hiatus, but until Thanksgiving, I'm off for a bit.)


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Double anal balls deep butt sex with black dudes. A definite 10 on the gay scale.
Even that super gay can't handle the D.A.B.D.B.S.W.B.D.
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Birmingham Best Inn Reviews
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I and my friends stood only one night in the family room, which is a big comfortable vintage room (perfect to film a horror movie hahaha), but it was much better than we expected. Just 18 min from the city centre by bus.
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Innate Vα14+ natural killer T cells mature dendritic cells, leading to strong adaptive immunity
Article first published online: 30 OCT 2007
DOI: 10.1111/j.1600-065X.2007.00561.x
Immunological Reviews
Volume 220, Issue 1, pages 183–198, December 2007
Additional Information
How to Cite
Fujii, S.-I., Shimizu, K., Hemmi, H. and Steinman, R. M. (2007), Innate Vα14+ natural killer T cells mature dendritic cells, leading to strong adaptive immunity. Immunological Reviews, 220: 183–198. doi: 10.1111/j.1600-065X.2007.00561.x
Publication History
- Issue published online: 30 OCT 2007
- Article first published online: 30 OCT 2007
- Abstract
- Article
- References
- Cited By
- dendritic cells;
- NKT cells;
- α-galactosylceramide;
- apoptotic tumor;
- cross presentation;
- maturation
Summary: The observation that the glycolipid α-galactosylceramide (α-GalCer) is a potent stimulator of natural killer T (NKT) cells has provided an important means for investigating NKT cell biology. α-GalCer is presented on CD1d to the invariant NKT receptor, leading to interleukin-12 (IL-12) production by dendritic cells (DCs) and to NK cell activation. We review our research on the tumor-protective properties of α-GalCer, particularly the major role played by DCs. We compared administration of α-GalCer on mature DCs with soluble glycolipid and found that DCs induced more prolonged interferon-γ (IFN-γ) production by NKT cells and better protection against B16 melanoma. Human α-GalCer-loaded DCs also expanded NKT cell numbers in cancer patients. α-GalCer-activated NKT cells were then found to induce DC maturation in vivo. The maturing DCs produced IL-12, upregulated co-stimulatory molecules, and induced adaptive immunity to captured cellular antigens, including prolonged, combined CD4+/CD8+ T-cell immunity to dying tumor cells. Surprisingly, co-stimulator-poor tumor cells, if directly loaded with α-GalCer ('tumor/Gal') and injected intravenously, also induced strong NKT- and NK-cell responses. The latter killed the tumor/Gal, which were subsequently cross presented by CD1d on DCs to elicit DC maturation and prolonged adaptive T-cell immunity, which lasted 6–12 months. These findings help explain tumor protection via α-GalCer and urge development of the DC-NKT axis to provide innate and adaptive immunity to human cancers.


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Training dogs is something a lot of us feel uncomfortable with. Unfortunately, by its very nature this will require you to shout at your dog, to pull on their lead and to deny them the things they want. Even when they're just trying to be friendly by jumping up to say hello, training a dog can mean ignoring them or telling them off and that can be heartbreaking.
Are you ruining your relationship with your dog by training them?
Why it's Okay to Train
The answer to this question is of course no. In fact, training your dog will make them happier because they'll have a better understanding of their role in the family and of how to behave. Of course you wouldn't treat a human in the same way but that's because the social structure of humans and dogs are very different. Dogs are highly social creatures and have a very distinct social structure that involves a clear 'leader' of the pack.
In other words, they are happiest when there is a hierarchy in your family and they naturally will fit in well to a social structure where you give them clear and distinct boundaries.
How to Punish Your Dog
Of course this still means that you have to punish your dog and that means they are going to be unhappy from time to time. The key here though is to find ways to punish your dog without upsetting them, which is actually more doable than you may think.
Instead of smacking your dog and shouting at them – neither of which is to be encouraged – the objective is instead to simply create a very clear and simple connection between a given 'bad' behavior and an unpleasant outcome. Squirting water or rattling keys can be a great way to accomplish this without making it feel 'personal' and without upsetting your dog.Full Review


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Allison Baver (born August 11, 1980) is an American short track speed skater. Baver trains with the US permanent winter sports Olympic team, in Salt Lake City, Utah. In the 2005-2006 season, she was ranked third overall in the World Rankings.
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Naomi plans a party so her friends can get to know P.J.; Austin returns and tries to help Adrianna with her music career; Annie confesses her feelings to Caleb.
After P.J. asks Naomi to be his wife, Annie learns he has financial motivation; Dixon tells Navid the label gave him a recording contract but didn't want Adrianna; Liam discovers Vanessa withdrew the balance of their joint account.
Navid decides to confront Liam on the red carpet at a movie premiere; Caleb and Annie give in to temptation; Austin asks his father (Billy Ray Cyrus) to help launch Adrianna's career in country music.
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Greenerways, Bug Spray, Organic Insect Repellent, 4 fl oz (120 ml)
By Greenerways16 Reviews
Expiration Date:?Jan 2019
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Our receiving department does its best to verify and then enter the correct expiration dates for all incoming products. However, discrepancies do occur from time to time. This being said, the exceptionally high turnover at iHerb ensures that our inventory is among the freshest in the industry.
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- Product Code: GRW-10903
- UPC Code: 094922109033
- Package Quantity: 4 fl oz (120 ml)
- Dimensions: 2.6 x 1.3 x 6.2 in, 0.3 lbs (0.14 kg)
Product Overview
- USDA Organic
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At Greener Days we believe in sustainable and healthy solutions for everyday life, while still being affordable
Suggested Use
Shake well. Apply liberally and evenly to exposed skin every 2 to 3 hours. For application to face, apply to hands and wipe on face, avoiding contact with eyes and mouth. Product may also be applied to fabric.
Other Ingredients
|Active Ingredients
|Citronella oil*
|Lemongrass oil*
|Cedar oil*
|Inter Ingredient
|*Certified Organic
Caution: Keep out of reach of children
May cause eye irritation. Avoid contact in or around eyes or mouth. It may cause skin irritation in rare cases. If skin irritation occurs, discontinue use and wash with soap and water. If irritation persists, seek medical help. Do not apply to children under 6 months of age.
Storage and Disposal: Store in a cool, dry place. Place empty container in trash or offer for recycling. 100% recyclable container.
iHerb Customer Reviews
I travel to the Philippines a lot working for a non-profit and find myself in rural mosquito-infested areas for long periods of time. It is not uncommon for me to get 20-30 bites every day that I am there. I have tried everything from numerous sprays to coils to electric diffusers to candles. None of them worked as well as this Greenerways Spray. If I had a lot of money, I would buy stock in this company if I could (and then import it to places like this). I spray once in the morning and maybe a touch up in the mid-afternoon before the mosquitoes wake up at dusk. I am BITE FREE now! This stuff WORKS! One day I was working in an office that is home to aggressive mosquitoes. I sprayed myself and literally saw the mosquitoes flying far away from me. About 4 hours later, I would notice 1 or 2 come a little close - but they still wouldn't come near my skin or attempt to bite. I would say this spray has works 100% for about 6 hours (of course this will differ person to person). Of course, the smell is not pleasant. It's a bit overwhelming when you first spray, but considering how effective it is, I don't care.


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It's A Mystery...Not entirely sure why some people judge me for this. And, they're the same people who also judge others for being hard to please or high maintenance. G-Zus Crisp, man! Will nothing make these judgmentals happy? ;p
Sorry about my typos- It looks like I should really check out my typing before I hit the post button.<br />
thanks for being understanding.
Nothing wrong with being amused easy. People can be so judgemental at times. Let they ae perfect. Be yourself and don't take to heart what other say. As long as you are happy, that is what matters.
hey ignore those who judge you .Alot of the time they judge to make themselves feel better .No one has the right to judge as none of us is perfect .Wouldnt it be a boring world if we were .If you want some sensible chat and a shoulder which wont judge and happy to listen or help if need ,I am here I have yahoo and msn if you need .Stay happy and remember you are your own person dont let others put you down.
They're only happy when they are pointing the finger at someone else. Makes the other people not look at them. I don't get it either. It's harder to be unhappy than happy isn't it?
Nope, the only way some can feel better about themselves is by beating others down. Enjoy life find your happiness.


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By Sara Jerome - 02/23/11 07:16 PM EST
Four Senate Democrats wrote to Majority Leader Harry Reid (D-Nev.) and Minority Leader Mitch McConnell (R-Ky.) on Wednesday to oppose GOP efforts to defund net neutrality rules through spending legislation.
The letter included Senate Commerce Communications subcommittee Chairman John Kerry (D-Mass.) and Sens. Al Franken (D-Minn.), Maria Cantwell (D-Wash.) and Ron Wyden (D-Ore.).
"Telephone and cable companies do not own the Internet. But if [the anti-neutrality effort] is successful, they will," the letter said.
The spending bill that passed the House on Saturday included language to prevent the FCC from using funds to implement its controversial net neutrality rules, which it passed in December over strong objections from Republicans.
"We ask you to object to any similar efforts here in the Senate. Such action aims to strip the FCC of its legal authority over modern communications and hand control of the Internet over to the owners of the wires that deliver information and services over them," the letter says.
The four Democrats also oppose use of the Congressional Review Act (CRA) to repeal the regulations, which is another House proposal.
They point to support for the FCC rules from "the original investors in Google and Netflix, the father of the Internet Tim Berners-Lee, a host of companies, venture capitalists, and hundreds of thousands of users of the Internet."
The signatories include the Senate's most ardent net neutrality advocates. Franken and Cantwell have written legislation to make the rules stronger. The aggressive language in the letter reflects that.
"Unfortunately, the House has decided that it knows better what is good for the Internet than the people who use, fund, and work on it," it says. "They claim to stand for freedom. But the only freedom they are providing for is the freedom of telephone and cable companies to determine the future of the Internet, where you can go on it, what you can attach to it, and which services will win or lose on it."
However, they also say it may have slightly better odds than repeal through the Congressional Review Act (CRA), because net neutrality is a lesser priority compared to top Democratic items such as healthcare. Advocates fear their priority could get lost in the mix.
Sen. Kay Bailey Hutchison (R-Texas), ranking member on the Commerce Committee, Sen. John Ensign (R-Nev.), ranking member of the Communications subcommittee, and McConnell introduced a resolution of disapproval last week to repeal the rules through the CRA.
Reid on Tuesday said that Senate Democrats would not accept any of a number of riders attached to the CR by the House.
"We're not going to resolve the issues of abortion, or net neutrality, or clean air on this CR," Sen. Charles Schumer (D-N.Y.) told reporters.
The House bill cuts $61 billion from 2010 levels, while Reid and Senate Democrats have said they will only accept much smaller cuts from current spending. If differences cannot be resolved, the government could shut down.
- Erik Wasson contributed to this report.
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text:
ECCO BIOM Hybrid Golf Shoes
$119.99 to $149.99
Product Information:
Take to the course in comfort when you sport the ECCO® BIOM Hybrid Golf Shoe. The anatomically shaped insole provides superior comfort and flexibility through every swing, and the water-repellant upper disperses perspiration to keep your feet dry and cool. The ECCO® Comfort Fibre System increases circulation for maximum ventilation, and the TPU outsole with over 800 traction angles ensures balance during play.
- Based on Men's sizes
- Hydromax™ construction keeps feet cool, dry and comfortable
- Water-repellant upper defends against perspiration for a fresh-feeling fit
- Anatomically shaped insole with padded polyester and EVA shell ensures superior support and flexibility
- ECCO® Comfort Fibre System increases circulation for maximum breathability
- Single-density TPU outsole with over 800 traction angles allows for total balance during your swing
- Made of yak leather
- Manufacturer's Warranty: 2-Year Waterproof
Country of Origin: ThailandWeb ID: 15349176
Customer Reviews:
Rated 4.8 out of 5�by 47 reviewers.
Rated 5 out of 5�by Rambo Great Shoe! They make tired feet feel young again!!!!! If you need a solid golf shoe then this is the one. It is like playing in running shoes but better. November 10, 2015
Rated 5 out of 5�by Kris Black Ecco Love this shoe. I bought the tan color several months ago. It is great, so ordered the black. September 28, 2015
Rated 5 out of 5�by mgolfer Love these shoes Most comfortable shoe (golf or otherwise) I've ever worn. Totally waterproof. Great traction and stability throughout the golf swing September 2, 2015
Rated 5 out of 5�by Greg5497 ECCO Rocks I am a big fan of the ECCO brand in general and this is my second pair of the BIOM Hybrid shoe. Very comfortable shoe that also provides incredible traction while on the golf course. I have had FJ shoes in the past and when my round was complete I could not wait to change shoes.....I do not have the same anticipation with my ECCO shoes. Very satisfied customer. August 24, 2015
Rated 5 out of 5�by BillB Very Comfortable Shoe I was a little hesitant about buying a hybrid golf shoe, but no more. This is probable the best and most comfortable golf shoe I've ever owned. I don't buy the most expensive or top of the line golf shoes, but I always spend $125+ for my shoes. For the price, these are the best I've had. I'm considering purchasing another pair as a back up. July 3, 2015
Rated 4 out of 5�by RLH good golf shoe I like the look of this shoe along with the fact that they fit well June 20, 2015
Rated 5 out of 5�by Bill Great Golf Shoes These are some of the best and most comfortable golf shoes I have owned. They were comfortable right out of the box. They provide a stable stance with no slipping. I was uneasy about buying hybrid shoes, but no longer. I just need to see how long they last compared to other shoes June 14, 2015
Rated 5 out of 5�by jk3 GREAT SHOES these shoes are incredibly comfortable. i spend all day on my feet at work. i know what comfortable shoes need to feel like, and i know what i feel like when they are not. i have always been a footjoy guy.....not any more. these are very well made. i look forward to updating this review at the end of the summer, to assess their durability. if they are anything like all their other products, they should be awesome. i play about 36 to 45 holes a week. these will get a work out. they are surviving the wet spring and summer fine, so far. one cannot make a mistake with these shoes. they fit my foot better than the hybrid 2's, but the price is what sold me. for an ecco shoe, they were a bargain. June 7, 2015
Rated 5 out of 5�by truckie4c Great Shoe Works well on and off course. Working in the pro shop enables me to move from inside to course easily. May 23, 2015
Rated 5 out of 5�by gpm Outstanding Golf Shoes Great golf shoes as you would expect from ECCO... like walking on air. May 22, 2015


text:
Boys from the Dwarf 2 by mikedawsWatch
©2010-2016 mikedaws
Pics of the Red Dwarf figures!
Lister's face kinda reminds me of Abed from Community
These look quite nice as models! Are you going to tackel teh Red Dwarf it self nextr? I have never seen awhole pic of the ship- just composites. You may want to put them on tha Space bug Ship they were flying around for a season on...
I have plans to make both Red Dwarf and Starbug -just figuring out how to do it at the moment!


text:
- 175Promote
Deleting the Dayby Ben Geiger
American Apparel T-shirts are made with 100% fine jersey cotton combed for softness and comfort. (Athletic Grey and Athletic Blue contain 50% polyester / 25% cotton / 25% rayon)
Wow, another masterpiece!
aw you are to kind. Thank you so much
love it
Thanks so much Christy
love the title, the art is great as always!
aw you are so sweet!
i love this madness of colours in the sky :))
:D Thank you so much :D I LOVE madness to so thank you even more :D you are kick A :D
Beautiful image, Ben :)
Thank you both so much!
amazing... love the colors
Thank you so much Rachel!
amazing colors !
Gorgeous colors! Love it :)
Simply stunning~ Truly captivating colors!! LOVE :) Nice work!
fantastic Ben!!!!!
wow!!!! good work! Xx
omg ben! this is BEAUTIFUL!
So awesome, Ben!!
Awesome! :)
Way cool
wow thank you all SO MUCH!
Absolutely gorgeous Ben!!
Thank you SO MUCH!
Love this :)
Thank you Stephen!
Beautiful work!
fantastic piece! beautiful colouring.
Thank you both!
This is amazing Ben!!!!
love this Ben!!
Thank you so much Sylvia!
✯ ✯ ✯ ✯ ✯ 👍 !!!
aw thanks so much Wayne!
Fabulous colours
Aw thanks so much Ally!
Nice work. Looks good across the product range too
Thanks so much!
Thank you Angelo!
LOVE these colors!
Thanks so much :D
una combinazione di colori che mi piace molto..
wow grazie mille! Lo apprezzo!
stunning sky
Thank you :D
love that title!
Thank you both so much!!!
See More Comments


text:
UNLV Runnin' Rebels
Sponsored By
Another Runnin' Rebel Going ProAfter two years as a Runnin' Rebel, sophomore forward Christian Wood has decided to leave UNLV early to enter the NBA Draft.
UNLV to Retain Dave RiceAfter a disappointing 18-15 season including an 8-10 record in the Mountain West the UNLV Runnin' Rebels have decided to keep Dave Rice on as head coach next season.
UNLV Falls On Tark NightWith the spotlight focused on honoring UNLV's former legendary coach, the Runnin' Rebels turned in a lackluster performance in falling to Boise State at the Thomas & Mack Center last night.
5 Things We Learned About The Runnin' Rebels After Two GamesThe Runnin' Rebels are 2-0, but they've fallen behind two smaller schools and have won the games by a combined three points.
Birch Snubbed At NBA DraftAfter projecting to hear his name called in the 2nd round of last night's NBA draft, Khem Birch was left without a team when the nationally-televised program ended.
Ryan Miller Joins UNLV Coaching StaffRunnin' Rebels coach Dave Rice announced the hiring of a new assistant coach on Wednesday.
Roscoe Smith Leaving UNLVRoscoe Smith, who led the conference in rebounding, is leaving UNLV to go pro.
Runnin' Rebels Shuttin' It DownLAS VEGAS, NV - For the first time since Dave Rice took over as head coach of the UNLV men's basketball team, there will be no appearance for UNLV in the NCAA Tournament.
UNLV KO'd From MWTLas Vegas, NV - In the end, it was San Diego State who punched the Runnin' Rebels' ticket out of the 2014 NCAA Tournament.
Just Win (3) BabyLAS VEGAS, NV - The numbers are simple: Three days, three wins, and the Runnin' Rebels earn a berth in the 2014 NCAA Tournament.
Runnin' Rebel Named Player Of The WeekRunnin' Rebel junior forward Khem Birch has been named Mountain West Men's Basketball Player of the Week.
UNLV Soars Past Air ForceCOLORADO SPRINGS, CO - Air Force proved to be no match for the scarlet red-hot shooting Runnin' Rebels Saturday afternoon as UNLV routed the Falcons 93-67.


text:
God I miss Homeworld
Waow waow waow!! This is terrific! Reminds me of the best atmospheres Ridley Scott and James Cameron brought us in their deep space trips.
Great how you reached such class with so few...
Great how you reached such class with so few...
Reminds me of Freelancer. Good old days, when we had sci-fi games.
what the creator said: ...
A plain just blue drawing, it gives an unexplainable feeling in a good way when i look at it.
This image is 95% Vue, the fog and hazy were part of the atmospheric setting in the render. Photoshop was used to touch up the colors a bit and add the signature.
very atmospheric.


text:
Whats the "Going rate" for a Yugo M70 Underfolder?
Tools and Technologies
Rifle Country
> Whats the "Going rate" for a Yugo M70 Underfolder?
Click Click Boom
July 18, 2008, 11:43 AM
I have never been in the market for a AK but a local Gunstore has a Yugo M70 underfolder for sale for $399.99. The rifle looks almost new.
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July 18, 2008, 11:56 AM
Thats a very good price, I would snatch it if you are looking for one-
July 18, 2008, 12:30 PM
Look arounf gunbroker and you will see thats a good price... Get it!
July 18, 2008, 12:32 PM
Great price if it is good/new. I 'd buy it.
Click Click Boom
July 18, 2008, 01:02 PM
Why do these AK's hold there value more than most? I would be a AK newbie if I decide to buy this rifle.
July 18, 2008, 01:06 PM
wood funiture or black?
either way a good price
check for canted front sight though.
Click Click Boom
July 18, 2008, 01:58 PM
It has a black pistol grip and black hand guard. The stock is a underfolder.
July 18, 2008, 02:12 PM
Why do these AK's hold there value more than most? Because they're over-engineered to the level of the proverbial brick outhouse.
Click Click Boom
July 18, 2008, 03:02 PM
The reciever is marked as the model M70AB2.
What makes them overbuilt compared to other mid grade AKs?
July 18, 2008, 03:09 PM
Definitely get it. You won't find a deal like that anywhere else.
The Yugo's have a thicker receiver and barrel, making them more durable and hopefully more accurate.
Yugoslavia didn't have the capacity to produce large amounts of rifles so they tried to make sure that their rifles would last longer. They are one of the better AK variants out there.
Cocked & Locked
July 18, 2008, 08:58 PM
yugo... :cool:
July 18, 2008, 11:59 PM
Buy that rifle... if not tell me where it is...
July 19, 2008, 12:04 AM
Buy it. 399 is cheap for a underfolder yugo.
The Yugos have a wide trunnion similar to the trunnions found on the RPK style AKM machine guns. The RPKs were squad support AKs that had a heavy barrel and wide trunnion and were designed for sustained full auto fire.
The Yugos used the same trunnion and heavy barrel on their standard guns so they are seriously overbuilt. I have one with about 800 rounds though it and I haven't cleaned it yet. Wondering how many rounds it will take before it starts cycling funny?
July 19, 2008, 12:09 AM
Oh yeah, the black plastic hand guards mean a quality Century build on the best receiver on the market. Century usually has a less than great reputation however they did great with their Yugo underfolders. They built them on the Nodak Spud receivers which are the best receivers. The Nodak Spud receivers are identified by the DC Industries engraved on them.
If they say "Vulcan" or "Hesse", you might not want it but the plastic handguards are a dead giveaway of a Century build, Century ran out of wood handguards about a year or two ago and started using the black plastic.
July 19, 2008, 01:46 AM
That's a fantastic price on that Yugo! I wish I could run across a few at that price...underfolders or fixed. Here's one I picked up a while back.
Click Click Boom
July 19, 2008, 12:09 PM
Whats the loation of the DC industries marking on the reciever?
July 19, 2008, 02:04 PM
Should be marked right below the serial # on the left side of the receiver. Look above the trigger in the pic I posted.
Century International Arms, Inc.
Mod: M70AB2 Cal: 7.62x39
Serial Number
D.C. Industries, Inc.
Saint Paul, MN USA
July 19, 2008, 03:55 PM
I got a Yugo underfolder from Classicarms a year or so ago,for $429. I'm glad to hear they're holding their value, or appreciating, but I ain't feeling the love here. I wish i'd have gotten the full stock version, or at least the one with the wood foregrips. BTW, Centerfire has sold out of the wood foregrips, anyone know of another source? ( other than paying through the nose and waiting forever with Ironwood).
July 19, 2008, 04:01 PM
I believe the Yugo AKs do not have chrome lined barrels, but I could be mistaken. Yugos captured in Iraq look like the inside of the barrels were sandblasted they are so bad. I know their SKS rifles do not have chrome lined barrels. This was because Yugoslavia had no chromium natural resources. Sounds like a good deal at $399, but be very careful about shooting surplus ammo that is corrosive. I don't think you can find the Yugos for less than $499 wholesale these days.
Click Click Boom
July 19, 2008, 06:18 PM
Modern wolf is non corrosive, correct?
July 19, 2008, 06:47 PM
Yeah, most everything i'm seeing around is non-corrosive. The only corrosive stuff i've seen lately is certain Yugo brass cased ammo, and if you can find it,the Chinese copper stuff.
Click Click Boom
July 19, 2008, 06:59 PM
Did the Yugo's ship with mags that had a last round bolt hold open?
July 19, 2008, 10:53 PM
This was because Yugoslavia had no chromium natural resources.
Yugoslavia is one of the richest chromium exporters in the world.
Bart Noir
July 19, 2008, 11:34 PM
Click Click, my Century Yugo UF came with 2 of those mags. I didn't even know about them until that. Then I bought a third one, costing twice what usual AK mags sell for.
That is the greatest possible choice for the AK. At least it tells the soldier that his gun is empty. Sure, the bolt goes forward when the mag is removed but the soldier at least is already reloading.
I wonder how many people have died in combat when they really, truly needed that AK to go bang, and all they got was the click on an empty chamber.
Bart Noir
Who didn't intend to make a weak pun in that last sentence.
July 19, 2008, 11:52 PM
that is a good price, I have a dealer friend who does better, but that is when he has them, and that is not too much anymore...
July 20, 2008, 12:12 AM
The Yugos are selling in stores for around $525-$550. The deals are gone.
July 20, 2008, 02:40 AM
More info about the Century builds. Century used new barrels on all of their Yugos, they don't have the shot out bores that a lot of the kit guns had.
Click Click Boom
July 20, 2008, 04:14 AM
Who made the Century barrels that they used for there builds?
I have heard mostly bad things abput CIA Builds. Why is there Yugo build OK?
July 20, 2008, 12:21 PM
Who made the Century barrels that they used for there builds?
I have heard mostly bad things abput CIA Builds. Why is there Yugo build OK? You should use the search feature on your various forums. Both of these questions have been answered many times.
Green Mountain supplies Century the barrels.
Century has learned it's lessons about building with in-house monkeys and now contracts the building out to competent builders. The company who does the Yugos for them is very good.
Click Click Boom
July 20, 2008, 03:32 PM
99% of the new topics on this site could be anwsered by the search option. This is a thread about CAI Yugo's. I just asked a simple question.
I do thank you for the anwser. I have discovered that a lot of information obout firtearms made and imported by CAI and similar outfits has a tendancy to change.
Is CAI still making the Yugo underfolders? I saw one at a gun show that had a $650 on it and cliamed to be new.
July 20, 2008, 03:48 PM
I got mine for 429 about 1o months ago. great gun
Click Click Boom
July 20, 2008, 04:50 PM
After reading this thread and similar Yugo underfolder threads I have seen two complaints stand out.
1.AK sights
2.The folding stock.
The stock makes it hard to get a good sight picture. I dont want to put some huge rail on an AK. Ultimak has a top rail that seems good for mounting a small red dot.
What is the general opinion of the Ultimak top rail?
What optic/red dot would you use on the Yougo underfolder?
July 20, 2008, 05:05 PM
After reading this thread and similar Yugo underfolder threads I have seen two complaints stand out.
1.AK sightsAK sights are good for minute-of-man at 200m (what they were designed for). People complain because they want laser beam accuracy out of them, but the Kalashnikov isn't designed for that . .
2.The folding stock.Underfolding stocks suck, in my most humble opinion. They were technologically available at the time of their design, but you see now what the Russians are using. If you want a folding stock in a Yugo AK, I recommend getting a fixed stock Yugo AK and using a side folding ACE stock on it. If you don't like it, you can always put the original wood back on it.
The stock makes it hard to get a good sight picture. I dont want to put some huge rail on an AK. Ultimak has a top rail that seems good for mounting a small red dot. Not sure what you consider "huge", but the standard commie rail mount is quite solid and allows the use of any available commie optic.
What is the general opinion of the Ultimak top rail? I've never seen a complaint about them.
What optic/red dot would you use on the Yougo underfolder?I'd install a commie side rail and use a Kobra.
September 27, 2008, 06:14 AM
Is there any possible options of getting the barrel lining chromed after purchasing a m70? I know they don't come chrome lined but if it was possible to get it done afterwards, I would like to.
September 27, 2008, 06:18 AM
Is there any possible options of getting the barrel lining chromed after purchasing a m70? I know they don't come chrome lined but if it was possible to get it done afterwards, I would like to. With enough money, anything is possible.
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Le Lot
by maredamay
Artist and traveler - this book combines my interests
Comment posted.
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Life and Art
Published May 11, 2014
Le Lot
Published November 24, 2012
Figurative drawing and painting by Robin Johnson
Published April 27, 2011
Nudes by Robin Johnson
Published December 17, 2010
DÃjeuner a Chez Philippe
Published March 22, 2010
An Unintentional Journey
Published February 17, 2010
Blurb Sites


text:
Ed Brown, former chef of The Sea Grill in New York, returned to Restaurant Associates this month to serve as senior vice president of food and beverage. In the newly created position, Brown is overseeing all aspects of the menu and drinks of the on-site company's portfolio, which includes more than 100 dining and catering accounts across the country. Brown had been consulting with RA for the past two years while he was also a partner at Ed's Chowder House, where he remains a chef ...
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Seoul: Asia's new fashion window?
Seoul is emerging as Asia's new fashion showcase, with the world's top luxury firms seeking to cash in on the regional trend-setting popularity of South Korean pop culture.
Over the past year, leading global fashion houses have upped their game in South Korea in a bid to reach those well-heeled Asians who take their fashion cues from popular Korean TV and pop stars.
Samsonite Asia sales up 18pc in 2014, driven by China market
Premium luggage maker Samsonite posted strong double-digit sales growth in all regions in 2014, led by Asia and North America.
The company said on Tuesday that net sales for the year ended on 31 December 2014 grew 17.3 percent to a record USD2.35 billion from the prior year. Adjusted net income jumped 9 percent to USD206.3 million. Excluding currency swings, adjusted net income advanced 12.3 percent. Adjusted EBITDA climbed 13.8 percent to USD384.3 million. It has been the fifth year the luggage maker posted double-digit growth in both net sales and Adjusted EBITDA.
Burberry opens first Beauty Box in Asia
The first Burberry Beauty Box in Asia was launched at the Coex mall in South Korea last month. Drawing inspiration from the Beauty Box flagship in London's Covent Garden, the store offers make-up including Burberry Eyes, Lips, Face and Nails, fragrances for men and women, and luxury accessories including eyewear, scarves and small leather goods for women.
Burberry said the space also offers customers the choice to interact with Burberry Beauty and accessories through physical and digital experiences.
Courts Asia on the move in physical and virtual worlds
Courts Asia Ltd, a Singapore listed retailer of consumer electronics and household furnishings, is looking to expand its regional reach after establishing a strong foothold in Singapore and Malaysia.
Courts, which only recently opened its first branch in Jakarta, says a move into Indonesia is long overdue. It plans more such stores in the near future as demand for consumer electronics and furnishings rises with the growth of the middle class.
Jack Wills adds two stores in Asia
UK fashion retailer Jack Wills has further expanded its presence in Asia by opening two new stores last week – one in Singapore, one in Macau.
The fashion brand made its Singapore debut on 4 November with a grand opening event at the new store in Raffles City Shopping Centre. Later in the week on 7 November, the store in Macau opened its doors in The Venetian Macau with a big "blue-and-pink striped" ribbon cutting ceremony.
ImagineX, ABG join hands to drive Juicy Couture's growth in Asia
ImagineX Group, Asia's leading retail, brand management and distribution company, has inked a long-term deal with Authentic Brands Group, LLC (ABG), the new owner of Juicy Couture, for the expansion of the lifestyle fashion brand in Asia.
"The partnership will provide the momentum to add more Juicy Couture stores throughout Asia; expand the brand's reach with new product lines; and support further regional growth initiatives," ImagineX said on Tuesday.
Burberry opens flagship store in Shanghai
Burberry recently opened its new flagship store at the Kerry Centre. It is the brand's eighth store to open in Shanghai, following recent openings within L'Avenue, K11 Art Mall and Hongqiao airport in 2013.
Wal-Mart sticking with slow and careful in Asia
After several missteps in its Asian expansion, global retailing giant Wal-Mart is taking a slow and careful approach, with expansion plans primarily aimed only at its three current regional markets, the Asia CEO told CNBC.
inProjects announces merger with EC Harris, part of the EUR2.5 billion global ARCADIS group
EC Harris, the leading global built asset consultancy, has joined forces with inProjects, one of Asia's foremost project management firms. The addition of inProjects strengthens EC Harris's presence in Asia and creates the region's leading programme and project management delivery organisation.
Flight 001 lands in Bangkok, eyes Asia expansion
Flight 001, the US-based specialty store for travel products, will expand business in Asia including Thailand to cope with the continued increase in the number of travellers across the region.
Executives were in Bangkok to officially open its first Thai shop at Siam Discovery Centre.
The company is looking to open stores in new markets, develop new product lines and build loyalty for its Flight 001 brand. Japan will be its strategic market in Asia, while Thailand will be its strategic base for the ASEAN market.


text:
AFEW x Onitsuka Tiger Papertoy
- AFEW x Onitsuka Tiger Papertoy
Papertoy Sneaker for the Koi Klub-Event
- Onitsuka Tiger Papertoy Sneaker created for the Koi Klub event at the AFEW-Store in Düsseldorf/Germany.
The sneaker was printed and pre-cut for a competition. customers were asked to draw their own designs on it for a chance on a pair of real OT-Sneakers.
In addition I cut out two giant versions of the sneaker and made my own custom version by glueing colored cardstock onto it.
Official AFEW-Recap: click
- Not quite sure what will happen to the template, but if you are interested in it, write a comment and I'll send you one.
Thanks for reading and making the blue button go grey.. ^^


text:
17.5" ENGLISH SADDLE- $175 obo INCLUDES SHIPPING!
17.5" English AP/Jumping Saddle with Medium Tree. Missing one billet on right side but still has other 2.
Asking $175 obo which INCLUDES SHIPPING!!!!
Additional photos and other english/western tack available here
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|Squad number:
|Durham Representative No.:
|Right Hand Bat
Twitter - @gmuchall
Date of birth - 2 November 1982, Newcastle upon Tyne, Tyne and Wear
Durham First Class Debut - April 2002 v Middlesex (home)
Gordon Muchall proved that he still has a lot to offer as a four-day cricketer during 2014.
The experienced middle-order batsman had to wait until mid-May for his first LV=County Championship appearance of the season, but some impressive scores ensured he retained his place for the rest of the summer.
A 12th first class century arrived at Trent Bridge in May, as Muchall struck a fluent unbeaten 158. He dominated the hosts' attack, which included Stuart Broad and Peter Siddle, and seemed set for a second double century of his career until heavy rain intervened.
The Newcastle-born star provided a number of memorable moments during the season, including a stunning diving catch in the NatWest T20 Blast match with Lancashire Lightning. He also featured 11 times during Durham's successful Royal London One-Day Cup campaign.
Muchall made his first class debut in 2002 and subsequently developed a reputation as a reliable performer who possesses the ability to time a ball beautifully.
He averaged over 45 in both 40 over and T20 cricket during 2013 and signed a two-year contract extension at Emirates Durham ICG.
Awarded a joint benefit year for 2014, Muchall was rightly recognised for over a decade of service at his home county.
First Class Highest Score - 219 (v Kent, 2006)
List A Highest Score - 101* (v Yorkshire, 2005)
Twenty20 Highest Score - 66* (v Derbyshire, 2013)
Best First Class Bowling Figures - 3-26 (v Yorkshire, 2003)
Best List A Bowling Figures - 1-15 (v Sussex, 2003)
Best Twenty20 Bowling Figures - 1-8 (v Lancashire, 2003)


text:
Definitions for quadrennialkwɒˈdrɛn i əl
This page provides all possible meanings and translations of the word quadrennial
Happening every four years.
Lasting for four years.
Origin: From quadriennial, from quattuor + annus.
Webster Dictionary
comprising four years; as, a quadrennial period
occurring once in four years, or at the end of every four years; as, quadrennial games
Origin: [L. quadriennium a space of four years; quattuor four + annus year; cf. L. quadriennis. See Quadrate, and Annual.]
Translations for quadrennial
From our Multilingual Translation Dictionary
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text:
Rukia's Feet by ubeliaWatch
©2011-2016 ubelia
Ichigo admiring rukia's beautiful feet
You're not supposed to post other people's work on deviantart; this is a site for artists, not plagiarists.
iv seen enough hentai to know where this is going. good job drawing it you have it down but you could have made her butt better


text:
Picture: Dick Van Dyke - 19th Annual Screen Actors Guild (SAG) Awards - Press Room Los Angeles United States Sunday 27th January 2013
Hollywood veteran Dick Van Dyke is back behind the wheel of a new Jaguar just days after his former luxury vehicle was destroyed by fire on California's 101 freeway.
The 87-year old Mary Poppins star was dragged out of his car by a Good Samaritan, who spotted the actor struggling inside as it filled up with smoke.
It was a lucky escape as the car burst into flames seconds later and by the time first responders arrived on the scene, the vehicle was completely engulfed by the fire.
Tmz.com cameras caught up with Van Dyke on Monday behind the wheel of a new Jag and he opened up about the fire drama.
He said, "In about 12 minutes it burned to a cinder."
The actor, who revealed he had called to thank the man who pulled him to safety but had yet to hear back from him, admitted he was stunned by the amount of people who pulled over to help him.
He added, "There are a lot of Good Samaritans left... There just happened to be an off-duty fireman and a nurse in the car almost behind me. They pulled right over because they thought I'd had an accident."
And Van Dyke insists he's fine now a week after the fire drama, joking, "Aside from being a little crispy around the edges, I'm in pretty good shape."


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If you have any questions regarding this program, wish to request additional vending services, or request a service/maintenance repair, please contact DATS at email@example.com or call 301-402-8180.
If you have the misfortune of losing your money within a vending machine or you do not receive your product, please refer to the DATS sticker on the machine. This sticker will inform you of where to go to obtain your refund. If there is no sticker on the machine, please refer to the listing below:


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Airing on Thursday, April 30, 2015: First up, we talk to Marketplace's Senior Tech Correspondent Molly Wood about Microsoft's bid to woo developers, and how the company is blurring the line between phone and computer with its new Windows OS. We'll also talk to Jonathan Zittrain, co-founder of Harvard's Berkman Center for Internet and Society, about Google's challenges in the EU antitrust suit, and whether or not it's possible for other search engines to compete with the Internet giant.
Airing on Wednesday, April 29, 2015: First up, we talk to Shyam Patil, an analyst at Wedbush Securities, about how Twitter's user problem affects advertisers. Plus, social media may have been used to gather people to the swelling protests on Monday, but it was also used once violence broke out to spread information through the community to help those coping with the damage and chaos. More on that. Finally, we'll talk to Marketplace's Scott Tong about home batteries and why grid defection already makes economic sense in some states.
Airing on Tuesday, April 28, 2015: First up on today's show, we'll talk to Frank Gillett, analyst at Forrester, on Apple earnings. Then, Thibaud Marcesse, a PhD student doing field work near India's border with Nepal, talks about using social media to check on friends after an earthquake in Nepal. And finally, we talk to Adam Ludwin, founder of Chain.com, about using the Bitcoin architecture to move money and other items-of-value online.
Airing on Monday, April 27, 2015: First up, we'll talk to David E. Sanger about hackers who gained access to President Obama's email. Plus, Marketplace Tech producer Meg Cramer talks about a new documentary that takes a look at the gender gap in the tech industry.
Airing on Friday, April 24, 2015: First up, we'll talk with Marketplace's Molly Wood about the issues surrounding the Comcast merger. And how well have you kept up with the week in tech news? It's time for Silicon Tally! This week, host Ben Johnson takes on Fred Benenson, data lead at Kickstarter and the creator of an all-emoji translation of Moby Dick, for an emoji-themed challenge.


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What is going on here?!
Exactly what is wrong with me?!
This feeling is wrong, but I can't change it.
Actions so wrong, but I can't stop.
Someone save me from myself.
At what price does this happiness come-
My heart?
Trading what for this pleasure-
My soul?
How did it come to this?
I've crossed a line and can't go back,
Not even to save myself.
No reasoning in this insanity.
The truth is right there in that hand.
I don't understand how I saw the sign and knew the deal,
Yet nothing said stop.
When did I lose myself?
I can't believe I'm acting like this.
I know it's crazy and I should know better . . .
Is anything okay?
What by ThornZfireWatch
©2012-2016 ThornZfire
I'm not sure whether this was written to yell at myself, just plain let out the pain inside me, or so that someone could tell me something to clear the confusion or life... but here it is for you to find your own meaning to.
What © Jennifer Clark
Do not reproduce, copy, modify, alter/distort or publish without permission
What © Jennifer Clark
Do not reproduce, copy, modify, alter/distort or publish without permission
I find this speaks to me in ways that make me very uncomfortable.


text:
WISN A-List
44 Caliber Media LLC has been voted as one of Milwaukee's top ten wedding videographers! Check out the list here.
Owner of 44 Caliber Media LLC, Eric Ellis, has been named runner-up in the "Best Filmmaker" category in the Shepherd Express Best of Milwaukee poll!
Need A Photographer?
If you need a professional photographer for your event, senior photos, portraits or anything else, give us a call! We offer very resonable rates and are willing to work with any budget.


text:
August 4, 2013
Brian Richie
To say that Florida's offensive line has had injury concerns during the past few seasons would be like saying the Titanic took on a little bit of water on its maiden voyage.Injuries have ravaged the Gator's front five men to the point where Coach Will Muschamp was forced to transform the Orange & Blue Debut spring game into a glorified practice session due to the lack of bodies. ...More... To continue reading this article you must be a member. Sign Up Now!
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Click Here To Watch This Video at Bait Bus
BaitBus: Straight men getting busy with gay sex.
Description: Even though today is the day after Thanksgiving you know we don't sleep here at Bangbros. We hit the mean streets of Miami looking for some fresh bait to stuff Steven like a turkey. We come across Bre
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(0) Comments | Posted April 1, 2008 | 11:28 AM
Two new episodes last night. Couple of things:
Spencer moves out to give Heidi "space."
As he's packing, he asks, "Is Empires of Sand your book?"
When I searched for Empires of Sand on Amazon, a couple of books came up. Clearly Heidi planted this line because...


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posted by Colm Hanratty | 0 Comments
I'm quite excited I have to say. Tomorrow I will be visiting Machu Picchu. I haven't felt like this since going to the Great Wall of China. It's one of those sights that you have seen countless times before, so seeing it for the first time is going to be special.
At the dinner table this evening there was a lot of chat though, about what time we would leave at. See, the way it works is this - the gates to Machu Picchu open at 6am. But the reason people go there early is to get tickets for Huayna Pichu, the big mountain that's in all the postcards. You can climb that if you feel the need. Personally, I'm not sure if I will. I didn't come here to climb that mountain…I came here to look at it.
Anyway, we will see what happens tomorrow.
Anthony sherlock said
" A fascinting blog, well written. Wish I could visit some of the places mentioned...
Cassandra C said
" Ha Long Bay, Vietnam! I went skinny dipping at night there, and there were l...
Alex Tyner said
Ram said
" Beautiful places i loved it find out some interesting places in the Himalayas
Josh Freeman said


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Last week the member states of the European Union invited the European Commission, the Brussels-based institution that deals with the day-to-day running of the EU, to take steps towards visa liberalization with Turkey.
The commission will probably publish an Action Plan this autumn showing how this procedure will be organized, what Turkey is supposed to do and what the EU is offering, when and under which conditions. The move was hailed by Turkish Foreign Minister Ahmet Davutoğlu as "a historic step." In the media it was claimed that the process is expected to be concluded in a period of two to three years and will allow 75 million Turks to freely travel to countries in the EU soon.
I do not want to spoil the party, but I am afraid some prudence is called for. First, on the present visa regime: There is no doubt that the system that is now in place for Turkish citizens to get a visa for Schengen zone countries is humiliating and deeply flawed. From a political point of view, it is impossible to defend the ongoing restrictions for Turkish citizens, while at the same time the EU has reached agreements for visa-free travel with other countries, for instance in the Balkans, with which is has not even started accession negotiations. On top of that comes a growing pile of jurisprudence from courts in the EU and its member states stating that the current visa requirements must be considered to be in conflict with the provisions of the 1973 Additional Protocol to the Ankara Agreement. In other words: Asking Turks for a visa is both politically and legally unacceptable.
The only reason why this malpractice continues is the deeply rooted fear that the EU will be flooded by Turks who will come and not go back. The recent rise of right-wing populism has only made it more difficult for EU politicians to do what, on rational grounds, they should be doing: treating Turkey in the same way as other countries have been treated in the past and gradually allow Turks to travel to the EU without a visa.
Is last week's agreement the belated recognition of this obligation by the EU? That would be jumping to conclusions. As an old English proverb puts it: "Don't halloo till you are out of the wood." Turkey is not there yet, definitely not within two or three years.
The positive news is indeed that for the first time the term "visa liberalization" has been used in an EU document that deals with Turkey. Till now other, vague phrases were invented to shy away from the inevitable conclusion that Turkey should be put on the regular EU visa track.
Reading last week's EU conclusions though, one cannot but wonder when the promise is going to materialize. There is talk of a "gradual and long-term perspective" and, more importantly, on progress that is conditioned on an effective and consistent implementation by Turkey of the so-called readmission agreement that forces the country to accept Turkish nationals and later on third-country nationals who have entered EU territory illegally from Turkey and are sent back.
The problem with last week's deal is that it involves a lot of pretending. The EU pretends to treat Turkey in a fair way but has put in place so many conditions that it will be quite easy for reluctant member states to slow down and frustrate real progress.
Turkey on the other hand pretends that it will only sign, ratify and implement the readmission agreement when the EU has started to produce effective visa exemptions. In Ankara the dominant belief is that the pro-Turkey court rulings inside the EU will eventually force the EU to become more flexible. Therefore, Turkey can wait and see and does not need to move itself in a substantial way.
The good thing about last week's agreement is that the wording and, to a certain extent, the mood has changed. The people responsible for implementing the deal inside the European Commission have the intention to make it a success. Still, the problem is with some EU countries that will only give in when all delaying tactics have been exhausted. In the meantime, Turkish politicians should be careful not to promise too much, and Turkish citizens should push their representatives to act on their part of the deal and not postpone the necessary measures that Turkey has to put into effect anyway


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Best Jazzercise Instructor (2001)
Brooke Sirhal
Need to lose a few pounds or gain some energy? Peppy and upbeat, Brooke Sirhal has several years of experience as a Jazzercise instructor, and she keeps things moving. The friendly ladies who work at the door welcome new students and make sure they don't get lost during the sometimes-complicated exercise routines. The first session is complimentary, so there's no excuse not to go jump around!
More Sports & Recreation Awards
Best Moonlight RideThe Moonlight Classic
Best Place to Cream a Golf BallD'Lance Golf
Best Rock That Looks Like George WashingtonRoxborough Park
Colorado State Parks
Best Colorado State University AthleteRick Crowell
CSU Rams Football


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The American Civil Liberties Union of Northern California (ACLU) has published a policy paper looking at the state's Shine the Light law of 2003. The paper looks at whether the law, now 10 years old, is still effective in providing transparency about how businesses handle personal data. "From revelations of widespread NSA spying to high-profile data breaches, the need to know what is happening to our personal information is more important than ever," the ACLU said.
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The College of Business and Economics develops high quality and innovative programs and resources, connects theory to practice in curricular, extra-curricular and research activities, and transforms students who will have a positive impact within Maryland and beyond.
College of Business & Economics
Accredited Programs
The College of Business and Economics offers rigorous and applied undergraduate and graduate programs in accounting, business and economics firmly rooted in the liberal arts. Our business and accounting programs are accredited by AACSB International, which places them among the top one percent of business schools worldwide.
Hands-on Learning Experiences
In addition to accredited coursework, students in the college can seek personal and professional growth opportunities tailored to their interests. Nearly all students complete at least one professional internship before graduating. Students also are encouraged to participate in exciting and enriching student programs and events, such as the college's signature business case competition, The Associate. The college's 18 student organizations provide another great outlet for students to grow professionally and gain leadership skills.
Dedicated Faculty and Staff
Distinguished faculty members serve not only as dedicated teachers but as mentors and advisers to students. Our faculty also influences the greater academic and business worlds through their research and scholarship.
Undergraduate Programs
The college's undergraduate program offerings include four majors, 11 concentrations/tracks and five minors. See our undergraduate programs.
Graduate Programs
Professionals seeking an advanced degree in a business field can pursue one of the college's three master's programs or four post-baccalaureate certificates offered by the college. See our graduate programs.
About Our People
By the Numbers
Internships in 2014-2015
Undergraduate/Graduate Students
Average Class Size
News & Events
Recent News
TU Alum to Lead 2016 Associate Competition
Brad Callahan, president of Vantage Resort Realty, will serve as the Presenting Executive for CBE's signature case competition this spring.
Visiting Scholar Shares What's Next for Wall Street
The College of Business and Economics welcomed Nicole Sherrod, managing director for trading at TD Ameritrade in Chicago, to campus on October 29 to speak to faculty, students and friends on the future of Wall Street.
Student-run Café Opens in Stephens Hall
Students in the entrepreneurial student organization Enactus opened a grab-and-go deli and café on the first floor of Stephens Hall.
Happening Soon
The Associate
5 p.m. Stephens Hall, Room 310
Case 1 Presentations
The Associate
5 p.m. Stephens Hall, Room 310
Case 2 Presentations
The Associate
5 p.m. Stephens Hall, Room 310
Case 3 Presentations
The Associate
5 p.m. Stephens Hall, Room 310
Case 4 Presentations
Contact Information
College of Business and Economics
8 a.m. - 5 p.m.


text:
Per un'intensa giornata di scuola, lavoro, palestra, appuntamenti o una combinazione di tutte le attività, questa borsa multifunzione ha tutto ciò che serve. Uno scomparto dedicato per il laptop da 15.6" e una custodia per il tablet oltre a spazio per tenere tutti gli accessori elettronici a portata di mano. Le cerniere molto grandi permettono di inserire libri, documenti o capi d'abbigliamento e una tasca nascosta a livello lombare è utile per riporre piccoli oggetti di valore. Questa borsa è una soluzione elegante per avere tutto sempre con sé.
(based on 6 reviews)
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By Nate
from Ohio
About Me High-End Shopper
Comments about Berkeley Deluxe Backpack:
I actually took this backpack hiking and it was pretty comfortable to lug around, I had a decent amount of weight in it and the straps felt easy on my shoulders. Plus you can fit a lot in it. And I use it for school, so overall great backpack.
Bottom Line
Was this review helpful? Yes / No
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Best backpack ever.
By Russ
from San Diego, CA
About Me Practical, Stylish
This backpack holds as much as my old backpack and looks significantly smaller. It is more stylish than any other backpack I can find. This is by far the best backpack I have ever owned.
Bottom Line Yes, I would recommend this to a friend
(1 of 1 customers found this review helpful)
You get what you pay for
By DFOI
from NJ
Case Logic makes great products....period. It's just that simple.I purchased this backpack to take my electronics with me on any trip. It sits in the passenger seat and I can always get to what I need at anytime. My iPad, my sunglasses, my iPod,......etc. All accessible because of the number of pockets.Zippers are always are concern with any product. I have never had a zipper jam, fail or break on any Case Logic product. My only complaint is that they no longer have their mobility assistance products.
(2 of 2 customers found this review helpful)
Promising design
By designer
from NY
About Me Practical
Appreciate the sophisticated color, features and ability to fully open the main compartment (like a carry-on). But, the straps need a more pronounced "S bend" to avoid rubbing against your inner arm. Also, the back fabric panel is not well ventilated for comfort on hot humid days.
Bottom Line No, I would not recommend this to a friend
I LOVE my new backpacl
By Ross
from Oakland
I love that the backpack has a separate section for the laptop. I think the pockets are smart and I love that the pack keeps it's shape and doesn't end up expanding. I use it for my commute but also for other outings as the pack is very practical.
(3 of 3 customers found this review helpful)
Great design
By RAM
from Glendora, Ca
About Me Bargain Hunter, Practical
I love backpacks, I have many & am always buying them hoping to find the perfect one. Well I think I may have just found what I have been searching for. I love this pack. It starts out light but maintains it's form, this is important to me. I most appreciate the fact that it stands up. Most backpacks don't stand but fall, usually forward unless it is completely full. This pack stands upright no matter how full or empty. I love the fact that the front pockets are positioned so as not to overweight the pack causing it to fall forward. The pockets are roomy and functional. The zippers are smooth and don't get hung up by the material. The material is light, strong, sturdy and fashionable. The straps are comfortable and I love the ways they are attached to the pack. I love the small but important little strap supplied to roll up the excess strap so that you don't have to deal with the tails ( the excess that hangs from the shoulder straps at the bottom where you adjust the strap.) The main compartments are roomy and functional. What more can I say this backpack is what I have been searching for. I am so glad I took the chance and purchased this pack, I had just about given up, thinking I was expecting something from a backpack that just didn't exist. Well it does exist in the excellent Case Logic backpack. Thank you Case Logic!!


text:
Picture: Sir Paul McCartney leaving his home this morning. It was alleged in tabloid newspapers this morning that he may agree a �25 million out of...
Sir Paul McCartney caught up on the phenomenon that is his YESTERDAY tune recently after a pal recorded the 10 most amazing covers for him.
The former Beatle still can't believe the song he wrote after waking one morning with it playing in his head has become the most covered tune of all time, and admits he hadn't heard many of the renditions by other artists.
MCCartney says, "I realised I'd hardly heard any of these 3,000 cover versions, so I had someone make me a CD of the 10 most amazing covers... Frank Sinatra, Elvis, Marvin Gaye, Ray Charles."
But in playing the covers, perfectionist MCCartney realised the greats had tweaked his lyrics.
He explains, "The funniest thing was, three or four of them changed the lyric very subtly. Fabulous.
"In the middle I go, 'I said something wrong, now I long for yesterday...' But they don't. They go, 'I must've said something wrong,' like, 'I doubt very much whether I did.'
"Certainly Elvis does. He's not admitting a thing."


text: I have a plastic Gatorade type bottle that I reuse. Between uses, I fill it with hot water and shake, and then empty it. Once I empty it, if I put the lid on and wait, the bottle eventually deforms and sucks in on itself. Then when I remove the lid it returns to normal. Why does it deform? Is it the same reason my red plastic gasoline container deforms when its left out in the summer heat all day? Does hot air take up less volume than cool air?


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William Hugh Tobin
Position: HB
Height: 5-11 Weight: 210 lbs.
Born: February 16, 1941 in Burlington Junction, MO
High School: Maryville
College: Missouri (school history) (Tobin college stats)
Drafted by the San Francisco 49ers in the 14th round (189th overall) of the 1963 NFL Draft.
Weighted Career AV (100-95-...): 3 (10660th overall since 1950)
Other SR Links: College Football at Sports-Reference.com
Let people know you like this site. Sponsor this page for $5. Your message will replace this ad.
Output includes all games from 1920 to 2015.


text:
Asuka by miyumiyuchancosplayWatch
©2013-2016 miyumiyuchancosplay
Nice perspective photo here!
What's it like to look in the mirror, and see Asuka there, like there's a real Asuka ?
This is an interesting effect: you can see the eyes of the model in the mirror image but not the eyes of the model directly; it is almost as if the reflection is looking at the model and not the model into the mirror.


text:
Tags: Kinky, maid, sucking, giant, black, cock, free, porn, amateur
Categories: Big Dick, Facial, Hardcore, Inter Racial, Teens
Pornstars: Melanie Jayne
Submited: 6 years old
Views: 23875
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Section 2257


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Teenagers share concerns at youth council
/ News
TEENAGERS will be sharing their concerns and ideas on how to improve services in their area with a council chief.
Fareham Youth Council will be putting questions and suggestions to guest speaker deputy council leader Councillor Trevor Cartwright today.
For more information call 01329 236100.
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Ghita Nørby
Born on January 11, 1935 in København, Denmark
Ghita Nørby as "Marie Hamsun"
This biopic centers on Knut Hamsun (Max von Sydow), a celebrated author in his native Norway. When fascism sweeps through Germany in the 1930s, the writer shocks his countrymen by allying himself with Hitler. Hamsun's wife, Marie (Ghita Nørby), also joins the Nazi cause, and goes so far as to tour in Germany, hosting public speaking engagements in the country. After the war ends, the author and his wife are further vilified in Norway, and ultimately sentenced for crimes against the state.
|Guldbagge Award (1997)
|Best Actress
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Activity from Swagbucks health advantage
We like healthy Swaggernauts…
Posted by Team Swagbucks on Tue, January 11th, 2011 at 2:00 pm
Well, why not look to Swagbucks to help you get over that nasty cold? Through Special Offers, you can print out the Swagbucks Health Advantage Card for FREE! Just visit the Swagbucks Health Advantage Program page, read the information, and click the button that says "Print Your Health Advantage Card Now." Once the PDF file opens, print it out, and cut it down to card size. Keep it in your wallet and show it at your local pharmacy!
This program is 100% free! You don't need prior health coverage, and there is no paperwork involved. You don't even have to be a Swagbucks member to use the card. Also, the card is not limited to one person – so feel free to use it for the whole family! Keeping your family nice and healthy? Pass the card onto a friend who might not be as lucky.
These cards come courtesy of ParamountRx, who we pride ourselves on being partnered with.
Print your way back to health!
Stay Healthy For Less
Posted by Team Swagbucks on Thu, December 2nd, 2010 at 3:00 pm
There's a nasty bug going around Swag Central right now. Everyone is doing the Dracula cough to protect those of us who aren't sick. THis is prime cold and flu season, and for the Swaggernauts out there who DO get sick, we have a way for you to save on prescription medication and all you […]
Save On Prescription Medication With Health Advantage
Posted by Team Swagbucks on Fri, October 22nd, 2010 at 3:00 pm
TSG is always looking out for his Swaggernauts – sometimes that means thinking of great new prizes for the Swag Store and Swagstakes, other times it's as simple as giving you a way to save money on your prescription drugs, especially at a time when many out there are struggling. If you want to take […]
Stay Healthy For Less
Posted by Team Swagbucks on Thu, October 7th, 2010 at 3:00 pm
With the fall season here and winter on its way, flus and colds are going to be floating around – it's just that time of year where a lot of people get sick. Prescription medicine from the doctor can help a lot, but is often REALLY expensive – even generic brands can cost a pretty […]
Save Money on Drug Prescriptions for FREE
Posted by Team Swagbucks on Tue, March 30th, 2010 at 7:00 am
TSG knows that times are tough, and many members of Swag Nation turn to Swagbucks to help offset some everyday costs. That's why I'm so excited about the Swagbucks Health Advantage Program, because it is a way for ALL Swaggers (and non-Swaggers) to save some cold hard cash on your prescription needs. Best of all […]
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Are you Wenying Kang?Claim your profile
Publications (5)0 Total impact
Article: [Study on plasma coagulation factor VII (FVII) levels and polymorphisms of FVII gene in patients with coronary heart disease].[Show abstract] [Hide abstract]
ABSTRACT: To investigate the plasma levels of coagulation factor VII (FVII) and polymorphisms of FVII gene in patients with coronary heart disease (CHD), and evaluate the effect of plasma FVII levels and FVII gene polymorphisms on CHD. Plasma FVIIa, FVII: Ag and FVIIc were measured and polymorphisms of FVII gene were analyzed in 149 control cases and 60 CHD cases, including 33 acute myocardial infarction (AMI) cases by a combination of polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and agarose gel electrophoresis. FVIIa, FVIIc in AMI group were significantly higher than that in control group, but FVII: Ag wasn't. There were no significant difference in plasma FVIIa, FVII: Ag and FVIIc between CHD and control group. The IVS7 genotypic frequency in AMI group was significantly different from that in control group. There was no significant difference in genotypic frequencies and allelic frequencies in other polymphism sites. FVII: Ag was significantly higher in -402A homozygote than that in -402G homozygote. Increased FVII levels, especially FVIIa and FVIIc in plasma, may contribute to coronary artery thrombosis. There was significant difference in IVS7 genotype frequency between control and AMI groups, but the rest weren't significantly different. FVII: Ag was significantly higher in -402A homozygote than that in -402G homozygote. Polymorphism of -402 G/A may play an indirect role in AMI by regulating plasma FVII levels.
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ABSTRACT: To explore the effect and mechanism of sodium butyrate on expression of human clotting factor VIII in vitro. Mouse NIH/3T3 cell line was transfected with recombinant plasmid vector pRC/RSV-BDD-hFVIII, which enclosed B-domain deleted (760aa approximately 1 639aa) human factor VIII cDNA (BDD-hFVIII cDNA). Then cells were incubated in Dulbecco's modification of Eagle's medium (DMEM) containing sodium butyrate for 24 hours, hFVIII: C and hFVIII: Ag in the cell culture medium were measured by ELISA assay and one-stage method, respectively. In addition, the effect of sodium butyrate on transcription of cDNA encoding the whole hFVIII, heavy and light chain of hFVIII was also investigated by means of run-on assay. After stimulation of sodium butyrate, the levels of hFVIII: C and hFVIII: Ag increased 70% than those of control. Run-on assay showed that sodium butyrate enhanced the transcription of cDNA which encoded heavy chain of hFVIII. Sodium butyrate can improve the expression of hFVIII through enhancing the transcription of hFVIII heavy chain encoding cDNA. It demonstrated that sodium butyrate had potential utility in inducing the expression of hFVIII in vitro.
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ABSTRACT: To identify the mutation of coagulation factor VII (F VII) gene in two pedigrees with hereditary F VII deficiency. F VII gene mutations were analysed in two propositi and their family members by direct DNA sequencing. Allele specific PCR and PCR combined with restricted enzyme digestion were used to confirm the detected mutations. Two gene mutations were detected in the propositus of pedigree A: G to C transition at position 6390 resulting in Trp40Cys and G to A at 11496 resulting in Arg353Gln, both are heterozygotes. The heterozygosity for polymorphism Arg353Gln was confirmed with the restriction enzyme Msp I digestion in his mother. In the propositus of pedigree B, there was a T to G transition at position 11482 resulting in His348Gln, heterozygosity of which was confirmed with Nsp I digestion in the propositus and his daughter. G to T transition at position 11514 resulting in Thr359Met was also found in the propositus of pedigree B, and the heterozygosity for Thr359Met was confirmed with allele specific PCR in the propositus and his son. Three missense mutations were found in two pedigrees with hereditary F VII deficiency. A novel Trp40Cys mutation was reported for the first time.
Article: [Identification of two novel mutation in two Chinese hereditary coagulation factor XIII deficiency families].[Show abstract] [Hide abstract]
ABSTRACT: To explore gene defect of hereditary coagulation factor XIII deficiency. PCR and gene sequencing or ARMS-PCR were used to detect the FXIIIA gene of peripheral white blood cell (PBC) from two Chinese hereditary coagulation factor XIII deficiency family members and 60 normal subjects respectively. The level of FXIIIA gene mRNA was tested by RT-PCR. (1) Nucleotide sequence analysis of the two probands' and their family members' DNA revealed that all of the three patients had homozygous missense mutation in FXIII A subunit gene. Proband 1 had a C to G transition at nucleotide (nt) 1 241 in exon 10 and proband 2 and his sister a C to T transition at nt 232 in exon 3 of FXIII A gene, which resulted in the substitution of Ser413 with Trp and Arg 77 with Cys, respectively. Family study showed that the two mutations were inherited from the parents who were correspondingly heterozygotes at nt 1 241 or nt 232. (2) The two mutations were not found in the normal subjects. (3) The FXIIIA gene mRNA level in the two probands was a little decreasing. It is the two novel mutations that results in FXIIIA deficiency. The two mutations of FXIIIA gene may affect its function or alter protein folding. The defective FXIII which is unstable and degraded rapidly in cytoplasm may be the main cause of FXIII deficiency.
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ABSTRACT: To accomplish a kind of therapeutic gene for hemophilia A, and observe the expression of human factor VIII (hF VIII) in vivo. Human clotting factor VIII cDNA with B-domain deleted (Delta760aa approximately 1639aa) was inserted into vector pRC/RSV to form pRC/RSV-hF VIII BD, which conjugated with in vivo liposome transfection reagent (DOTAP-Cholesterol) to accomplish a kind of therapeutic gene, pRC/RSV-hF VIII BD-DOTAP-Cholesterol. Mice were injected with pRC/RSV-hF VIII BD-DOTAP-Cholesterol i.m. and sacrificed 48 hours, 10 days, 20 days, 30 days, 40 days and 50 days later, respectively. Tissues such as heart, liver, spleen, lung, kidney and muscle were harvested, the distribution and transcription as well as expression of hF VIII BD cDNA were detected by means of PCR, RT-PCR and immunohistochemistry techniques. In addition, the antigen and antibody of hF VIII in plasma were measured. There was high expression of hF VIII in plasma and tissues at the 48(th) hour after injection. On day 10, antigen level of hF VIII in plasma reached its peak, 17.55 ng/ml, and gradually reduced later. The antibody of hF VIII in plasma emerged on day 10 after injection, and increased and gradually reached 37.06 U/ml on day 50 after injection. PCR, RT-PCR and immunohistochemistry showed that hF VIII BD cDNA and its transcription as well as expression existed in all kinds of tissues, and lasted longer in spleen, lungs and kidneys than in heart, liver and muscle. Therapeutic gene, pRC/RSV-hF VIII BD-DOTAP-Cholesterol, produced by combination of pRC/RSV-hF VIII BD and DOTAP-Cholesterol liposome can express human F VIII successfully in vivo, which lays an experimental foundation for curing hemophilia A by gene-drug in clinic.
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Ruijin Hospital NorthShanghai, Shanghai Shi, China