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August 19, 2012
Camp closes; Day 16 report
LISTEN: Danny Hope after practice
The careers of sophomore linebacker Mike Lee and freshman safety Jordan Shine have come to an end after not passing pre-training camp physicals.
Coach Danny Hope made the news official after practice Sunday, the final day of Purdue's camp, 13 days before the season-opener vs. Eastern Kentucky.
Lee, who had seen limited action as a reserve last season, was out for the spring after experiencing concussions. He had not returned to camp. Shine, an incoming rookie, has a neck stability issue, according to Hope.
The duo, assuming they decide to stay in West Lafayette as students, will receive medical hardship scholarships, but will not count against the 85-scholarship limit. And Hope says they could remain with the Boilermakers, but in a non-playing capacity.
"There are a lot of roles those guys could fill," Hope said. "Obviously, if they're going to go to Purdue and remain on scholarship, we want them to be involved in the program and still be part of the team. We have a plan to keep those guys involved."
Caleb TerBush entered training camp as the No. 1 quarterback, and he leaves with the same title.
Barring anything unforeseen, the senior signal-caller will take the first snap against Eastern Kentucky Sept. 1.
"Caleb has had an outstanding camp," Hope said. "When it is all said and done, we've had a lot of guys who have gotten better and it'd be hard without a staff meeting to try to say who was the most improved player on the football team, but it might be Caleb TerBush.
"He ended the season really strong last year and hasn't just picked up where he left off at, but has really progressed in his play. He knows where he's going with the ball now, oftentimes pre-snap and oftentimes right after. He's been able to deliver the ball in a hurry with a lot of accuracy. He's practicing exceptional right now.
"He's our starting quarterback. He has been and he's taken his game to another level."
Senior Robert Marve is the No. 2, and Hope says he's improved from last season, as well.
"He manages the offense a lot better," the fourth-year coach said. "He's been very accurate with his passes."
Junior Rob Henry is third on the chart, but has been somewhat limited as he returns from an ACL tear a year ago. He's also seen action during camp as a return man and at other skill positions.
"Still struggling with some soreness," Hope said. " It's a day-to-day basis, but I expect his recovery to be very quick and for him to get a lot more in coming days after getting a couple days off."
Hope said Purdue accomplished many of the earmarks it set before training camp.
It wanted to come in off a good summer conditioning program, not lose anyone to academics and become more disciplined, among other goals.
Hope mentioned those three as positives.
"We're right on course," he said.
"We wanted to go out there and practice to a certain standard. That's really important to our football team. We have standards in regards to lining up fast and lining up right, and in regards to pursuit to the football, when the ball is on the ground, scooping it and scoring. A lot of little things, but I felt we made progress in those areas."
Purdue had numerous players sit at times during camp, but only a couple are ruled out for the opener.
Receivers Tommie Thomas (foot) and Ishmael Aristide (knee) will not play, nor will running back Ralph Bolden (ACL recovery).
"He probably won't be ready in a couple weeks, but it looks like he might able to get ready sometime this season," Hope said of Bolden, who had knee surgery in December.
Others have battled minor injuries. Receiver Gary Bush (hamstring); receiver Antavian Edison; tight end Carlos Carvajal (groin, abdominal strain); Henry (knee); Gabe Holmes (knee); and nickel back Normondo Harris have been limited at times.
But none are expected to miss a Saturday.
"We're in good shape," Hope said. "I anticipate going into the first game with just about everybody ready to go."
Purdue practices for another week before getting into game prep.
It's got several things to work on, Hope says, but chief among them might be ironing out its pass efficiency, from the quarterbacks to pass-catchers, and everything else. But if those are solidified, he likes the potential of the passing game.
"No. 1 is the offensive line," Hope said. "If we can keep it clean across the front, we have the firepower to do very well from a passing standpoint, and that would really make a difference to our football team."
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2 posts tagged with fbi by rdr.
Displaying 1 through 2 of 2.
The F.B.I. knew al-Qaida was going to hijack planes in the U.S. a year before 9/11.
A missed clue. Niaz Khan walked into an F.B.I. office and told them that he had been provided money and training by al-Qaida with the aim of hijacking a plane in the United States. [more inside]
FBI finds a second batch of McVeigh documents.
FBI finds a second batch of McVeigh documents. I hestitate to start a new thread about this but I just wanted to point out this story.
Page: 1

subset: commoncrawl


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Texas Instruments LM3463 Dynamic Headroom Controller is a six-channel linear LED driver with Dynamic Headroom Control (DHC) interface that is specialized for high power LED lighting applications. TI LM3463 delivers accurately regulated current to LEDs while maximizing the system efficiency. The variation of the output current of every output channel in the temperature range of -40°C to 125°C is well controlled to less than ±1%. The output current of every channel is accurately matched to each other with less than ±1% difference. By interfacing TI LM3463 Dynamic Headroom Controller to the output voltage feedback node of a switching power supply via the DHC interface, the system efficiency is optimized automatically. The dynamic headroom control circuit in the LM3463 minimizes power dissipation on the external MOSFETs by adjusting the output voltage of the primary switching power supply according to the changing forward voltage of the LEDs. The dimming control interface of the LM3463 accepts both analog and PWM dimming control signals.
Texas Instruments LM3463EVM Evaluation Module (EVM) is designed to evaluate the LM3463, a dynamic headroom controller. It is designed to drive six strings of high brightness LEDs at maximum supply voltage up to 95V. Each output channel of the LM3463 evaluation board is designed to deliver 200mA of LED driving current. The LED turn on voltage is set to 48V by default, thus the board is able to deliver up to 57.6W total output power. The six output channels are divided into 4 individual groups to facilitate average LED current control by means of PWM dimming. The PWM dimming control interface of the LM3463 can accept standard TTL level PWM signals, analog voltage or serial data to control the dimming duty of the four LED groups individually. The analog dimming control interface accepts an analog control voltage in the range from 0V to 2.5V to adjust the reference voltage of the linear current regulators, which enables true LED current adjustment. This evaluation board is designed to be connected to an external primary power supply. Using three connection wires, the VIN, GND and VFB, the dynamic Headroom Control (DHC) circuit of the LM3463 adjusts the output voltage of the primary power supply to maximize system efficiency.
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Team Raymarine was delighted to accept the Sailing Today award for Gear Innovation (in association with NASA Marine) for the Raymarine Evolution autopilot in the inaugural awards at the Southampton Boat Show
Spot potential engine and mechanical room problems before they happen with the FLIR AX8 thermal monitoring system for marine applications
The 14th major quarterly release of Raymarine's LightHouse II software introduces a range of new sail-specific tools and features that are compatible with all Multifunction Display platforms.
Get a powerful and flexible navigation experience from Navionics, C-MAP by Jeppesen and Raymarine LightHouse Charts - Transform the way you navigate with fully-featured vector charts, dynamic raster charts, plus 3D satellite chart options.
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November 24, 2008
Big 12 builds on recent success
Justin Young
Rivals.com Basketball Recruiting Senior Writer
Kevin Durant tore up the league and spent one memorable season at Texas. Michael Beasley followed him with a historic freshman campaign at Kansas State, and Kansas won the national championship last season.
The bar has been set pretty high in Big 12 basketball, and it has been an easy sell in living rooms across the country. Seven of the 12 teams in the conference are among the top 25 recruiting classes nationally, including three in the top 10.
Texas is the big winner within the conference rankings and nationally. The Longhorns are the second-rated class in the country and tops in the Big 12. Kansas is close behind at No. 4 nationally. Oklahoma checks in at No. 10 and Oklahoma State is No. 11.
Best storylines
Baylor made a major recruiting splash at the end of the summer, and the Bears did it without even landing a commitment. A lot has been made about Baylor hiring Dwon Clifton, a former player at Clemson and UNC-Greensboro. Clifton also coached John Wall, the nation's top overall player, on the AAU circuit with D-One Sports.
A year ago, no one in the Big 12 knew who Thomas Robinson was. In fact, very few coaches at the high-major level knew much about the star from the Washington, D.C., area.
After showing flashes of brilliance in the spring, dominating during the dead period in June and exploding in July, the hoops community knows plenty about the high-energy forward who is now at Brewster Academy in Wolfeboro, N.H. The soft-spoken and humble forward ended the summer as one of the top rebounders in the nation and one of the most coveted players in the country.
Kansas had to make up a lot of ground to get in the good graces with the five-star forward. Robinson visited Lawrence and committed three weeks later.
The talent from the Washington, D.C., area is getting to know the I-70 roadways quite well these days. Kansas State continues to tap into the D.C. Assault AAU pipeline for top hoops recruits.
Five-star forward Wally Judge and top 100 guard Rodney McGruder became the fifth and sixth recruits from the D.C. Assault program to ink with the Wildcats since 2007.
Assistant coach Dalonte Hill was an assistant coach within the program before joining the college coaching ranks.
Biggest recruiting coup
The line to get inside the recruitment of Avery Bradley looked like the registration line at the NABC coaches convention at the Final Four. Everyone wanted to get in with the five-star guard.
Prior to the July period, Bradley said UCLA, USC, Texas, Memphis, Kansas, Arizona and Florida were his top choices. All of those schools posted head coaches on the sidelines to see and be seen with the top defensive guard in the nation.
In the end, the kid who grew up in Pac-10 country in Tacoma, Wash., and is currently at Findlay Prep in Nevada, picked Texas. His presence will be felt immediately in Austin.
Budding rivalry
Two of the cities top scoring point guards � Raymond Penn and Tommy Mason-Griffin � inked with schools in the Big 12. Penn is headed to Oklahoma State, Mason-Griffin to Oklahoma. They both know how to pump in the points. The two have locked horns in Houston, and there is a great debate as to who has the upper hand. The duo traded buckets in a fall league game, both scoring more than 30 points.
The rivalry will spill over to college and will be one to watch for years to come.
Biggest miss
For at least three years, Kansas basketball fans were talking about what it would be like to see Xavier Henry on the floor of Allen Fieldhouse decked out in Jayhawks gear. No one could fault fans for thinking such grandeur thoughts.
Then things started to change when C.J. left his post within the New York Yankees' minor league system and joined the Memphis basketball program. Less than four months later, Xavier decided he would suit up for John Calipari instead.
Henry's decision was one of the biggest switches of any player in the class and an obvious blow to the Jayhawks.
Daniel Orton grew up in Big 12 country in Oklahoma City. He was aggressively pursued by Oklahoma and Oklahoma State as well as Kansas, but he found his fit at Kentucky with Texas native and former Texas A&M coach Billy Gillispie.
Orton, a five-star prospect and one of the top centers in the country, visited Kentucky several times and fell in love with the Wildcats' culture. His game would have transitioned quite well in the Big 12 had he decided to go that route.
Prior to moving to Tampa, Fla., for his senior year, John Henson lived in Round Rock, Texas. Henson was 20 minutes north on I-35 from the Texas Longhorns, and Rick Barnes and his staff recruited Henson prior to his accession up the recruiting rankings.
Henson committed to North Carolina in January and used the spring and summer to lock himself into a top 10 national ranking. His move to Tampa, Fla., certainly helped ease the blow to the Longhorns. Texas recovered nicely, landing Bradley and Jordan Hamilton, who are both top 10 national prospects.
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Washington Post/CNN media critic Howard Kurtz held an online Q&A today. In light of last week's Q&A held by Post executive editor Marcus Brauchli, in which Brauchli ducked tough questions in favor of queries about fonts and byline formats, I submitted two questions to today's Kurtz Q&A:
You reported a week ago that Post exec editor Marcus Brauchli says the NYT misunderstood him over the summer; that he didn't say he had been unaware the Post's salon dinners were marketed as off the record. But Politico's Michael Calderone says Brauchli told him the same thing he told the Times, and he interpreted it the same way.
Have you asked Brauchli about this? It seems hard to believe that 2 different reporters at 2 different news orgs would misinterpret 2 different Brauchli comments precisely the same way.
So, CNN did a 4-hour immigration special. CNN's Lou Dobbs is one of the nation's leading critics of immigration policy. One of the experts interviewed for the special specifically criticized Dobbs' reporting. And CNN edited that criticism out before airing the interview.
Now, those two questions have something in common: They both raise issues that are uncomfortable for people who sign Howard Kurtz's paychecks. Actually, they have something else in common: Kurtz didn't take either of them.
Kurtz did take a question about the hugely-significant Steve Phillips ESPN sex scandal, a throwaway about the name of his television show, a conspiracy-theory rant about the government and media "terrorizing" people about H1N1, a few questions about sports programming, a comment about the Post's redesign, and several questions about CNN's competitors Fox News and MSNBC.
Obviously, these WaPo Q&As exist largely to promote the Post and its work. It's a shame some Post employees don't also see them as an opportunity to be accountable to their readers and take tough questions.
(It should be noted that some WaPo Q&A participants don't seem to duck difficult questions. Perry Bacon's last few sessions are an example. I've been pretty critical of several of his comments during Q&As, but he deserves credit for responding to pointed queries from readers.)
From the October 26 Associated Press article:
In a blind test, the AP gave temperature data to four independent statisticians and asked them to look for trends, without telling them what the numbers represented. The experts found no true temperature declines over time.
"If you look at the data and sort of cherry-pick a micro-trend within a bigger trend, that technique is particularly suspect," said John Grego, a professor of statistics at the University of South Carolina.
Yet the idea that things are cooling has been repeated in opinion columns, a BBC news story posted on the Drudge Report and in a new book by the authors of the best-seller "Freakonomics." Last week, a poll by the Pew Research Center found that only 57 percent of Americans now believe there is strong scientific evidence for global warming, down from 77 percent in 2006.
Global warming skeptics base their claims on an unusually hot year in 1998. Since then, they say, temperatures have dropped - thus, a cooling trend. But it's not that simple.
Since 1998, temperatures have dipped, soared, fallen again and are now rising once more. Records kept by the British meteorological office and satellite data used by climate skeptics still show 1998 as the hottest year. However, data from the National Oceanic and Atmospheric Administration and NASA show 2005 has topped 1998. Published peer-reviewed scientific research generally cites temperatures measured by ground sensors, which are from NOAA, NASA and the British, more than the satellite data.
The recent Internet chatter about cooling led NOAA's climate data center to re-examine its temperature data. It found no cooling trend.
"The last 10 years are the warmest 10-year period of the modern record," said NOAA climate monitoring chief Deke Arndt. "Even if you analyze the trend during that 10 years, the trend is actually positive, which means warming."
The AP sent expert statisticians NOAA's year-to-year ground temperature changes over 130 years and the 30 years of satellite-measured temperatures preferred by skeptics and gathered by scientists at the University of Alabama in Huntsville.
Statisticians who analyzed the data found a distinct decades-long upward trend in the numbers, but could not find a significant drop in the past 10 years in either data set. The ups and downs during the last decade repeat random variability in data as far back as 1880.
Saying there's a downward trend since 1998 is not scientifically legitimate, said David Peterson, a retired Duke University statistics professor and one of those analyzing the numbers.
Identifying a downward trend is a case of "people coming at the data with preconceived notions," said Peterson, author of the book "Why Did They Do That? An Introduction to Forensic Decision Analysis."
DeLay: To regain power, conservatives need "communications organizations that can... match Media Matters"
Beck attacks Jane Hall: "idiot that left Fox ... Don't let the door hit you on the ass when you leave"
Andrew Breitbart's obsession with "MediaMutters" takes him 'round the bend
Breitbart develops "MEDIAMUTTERS" obsession; perhaps should spend more time fact-checking his site
Breitbart burns Beck, Dobbs, right-wing media with false claim of "Community Organizers Pray[ing] TO" Obama
Obama Derangement Syndrome truly knows no bounds in Malkin's hate-driven world. It's a demented zone where children are always targeted for political attack. Incredibly, Malkin today unveils dripping contempt for White House aide David Axelrod and his epileptic daughter. Why? Because Axelrod had the nerve to appear on 60 Minutes and discuss the disease.
Here's Malkin in full-shriek mode:
So is White House senior adviser/Astroturf master/Big Pharma beneficiary David Axelrod, who appeared on 60 Minutes with Katie Couric this weekend to talk about the epilectic daughter he never sees because he's so busy trying to salvage his boss's government health care takeover plans. The AP dutifully recycled the story -- which itself had been recycled from February's Parade magazine.
Stay classy Michelle.
From the October 26 edition of Fox News' The Live Desk:
Luntz births another GOP talking point: It's a "government option" not a "public option"
Because the Chicago Tribune columnist completely botches the facts of the film in the process of becoming the latest media elite granted access into the CW Kingdom by dutifully concluding the White House should not fact check Fox News.
Here's Page's complete misreading of the classic 1970's film:
In fact, Fox is what their defenders say it is, not a political organization but a news operation. It just happens to have some strong right-wing voices like Beck and Hannity who happen to be two of Fox's biggest audience attractions. Such phenomena were forecast in the movie "Network" in 1976. Back then the idea of a half-deranged demagogue set loose on a national audience for the sake of ratings still sounded far-fetched. These days the movie looks almost like a documentary.
Um, wrong. That's not what Network was about, although Page is hardly alone in misstating the facts of the film. It routinely gets referenced, incorrectly, in media profiles of Glenn Beck, who we're told is just like the stark raving mad man from Network. In fact, Beck loves to push the idea that he's a modern day, I'm-mad-as-hell everyman like Howard Beale
It's BS.
Beale's unvarnished on-air rants from Network targeted conformity, corporate conglomerates, and the propaganda power of television. (Ironic, no?) Beale was non-partisan and rarely even mentioned politics in his (fictional) primetime rants. Beck, by contrast, is uniformly partisan as he unleashes his anger against, and whips up dark scenarios about, the president of the United States.
Big difference.
From today's Washington Post online Q&A with Howard Kurtz:
Bluffton, SC: In your blog on Friday you wrote this referring to MSNBC and its liberal hosts: "though that channel does give Joe Scarborough three hours a day, while no liberal has a show on Fox News." Although Joe considers himself a conservative the majority of the guests (not to mention his co-host) are decidedly liberal. And when it comes to interviewing members of Congress, Democrats seem to get twice as much airtime as Republicans. Poor Paul Ryan got a grand total of 3 minutes on Friday's show.
Howard Kurtz: I haven't noticed a tilt on the Morning Joe guest front at all. During the campaign, McCain people came on as often as Obama people. Peggy Noonan is a regular, and Pat Buchanan is on an awful lot. So I think it's fair to hold up Scarborough as an exception to MSNBC's generally liberal opinion lineup.
Washington Post reporter Perry Bacon, during an online Q&A today:
Perry Bacon Jr.: The public option shift was dramatic and in many ways, I don't quite know what happened. I think we may have misstated the strength of the opposition to the public option in the first place, but i think the members changed their view on this as well.
Well, that has been obvious for months. What Bacon doesn't address, and should, is why the media overstated the strength of the opposition to the public option. What could they do better the next time? Does this indicate they listen to the wrong "experts"?
It's not like there haven't been clear indications all along that the media was overstating the strength of opposition to the public option. Why didn't they pay attention? Bacon gave no indication that he's considering that question.
Glenn Beck promotes the ludicrous lie that Nancy Pelosi is going to try to ban Fox News from "covering Congress":
If you follow the link, you'll see why this is an obvious lie: in the made-up quote attributed to Pelosi, she talks about "the efficacy of single payer health insurance." Single-payer, of course, is not on the table.
So which is it: Is Glenn Beck dumb enough to believe the quote was true, or dishonest enough to hype it knowing it wasn't? Or both?
Journal columnist Kimberley Strassel is petrified by the mafia-style brand of hardball politics that the Obama White House practices. (i.e. "The gang") Did you know he's from Chicago?!
The idea that the right-wing media is trying to portray Obama has some sort of street-fighting ruthless pol strikes me as comical since it's the exact opposite of the impression most Americans seem to have of the centrist, low-key president. The fact that the charge is so far off the mark may be why Strassel has so much trouble filling in the blanks in her column about how "bare-knuckle" the Obama crew is. The examples she points to are really quite lame.
Like this [emphasis added]:
This summer Arizona Sen. Jon Kyl criticized stimulus dollars. Obama cabinet secretaries sent letters to Arizona Gov. Jan Brewer. One read: "if you prefer to forfeit the money we are making available to the state, as Senator Kyl suggests," let us know.
The horror! Cabinet secretaries "sent letters."
Or this one:
When Sens. Robert Bennett and Lamar Alexander took issue with the administration's czars, the White House singled them out, by name, on its blog.
Oh mercy! The White House singled a senator out by name, on its blog.
If Stressel's going to preach this meme in the future, I suggest she come up with some actual proof of Obama's "bare-knuckle" ways, and leave out the examples of pedestrian politics she breathlessly cites here.


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Chuck Kearns
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I have been into this hobby over 30 years and never get tired of it. It's a hobby that always will receive "new subjects". I must give accolades to my graving "homies": Arthur Koykka (RIP), Scott Wilson, Richard Silverman (RIP), Roger Sinclair(RIP), David Lotz (RIP), Kim Eazell, Jim Dougan,and David Brown. They don't all post here, but they do know their stuff when it comes to researching burials.
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Lorenzo Brieba
RE: Jimmy Burke
I think you're right.. although they both died in 1996, James J Burke was interned on April 18.. DOD was April 13.. and yes your DOB is correct.. All we know for sure is their date of death especially when they die in prison. Another issue was Burke's real last name being Conway.. Most gangsters lie about their true age, their name etc. making their graves difficult to locate. Their RAP sheets often consist of multiple names which is why they are only identified by their NYSID.
Added by
Lorenzo Brieba
on Feb 03, 2016 12:08 PM
B.J. Waters
Ronnie Kieffer
Are you sure he was born and died on the same day? I had looked and found no death record for him on the index, which usually records such births/deaths even if the child only lived for a few minutes. I am not doubting you, just curious about your source. The California Death Index does not include stillborns, only babies who would have had a birth record and death certificate issued.
Added by
B.J. Waters
on Nov 05, 2015 4:49 PM
John "J-Cat" Griffith
Totty Ames info - - -
Hello Chuck and thank you for the plot grave info for actress Totty Ames. I have updated that to her bio and I she will be accepted to famous status. Best always,
Added by
John "J-Cat" Griffith
on Sep 07, 2015 9:38 AM
Autistic Wonderboy
Trump headstone
Thank you!
Added by
Autistic Wonderboy
on Aug 28, 2015 4:19 PM
Bill T. Whitis
RE: Robert & Mattie Newhouse
Upon closer review of his obituary, he had a memorial service not a funeral. And no pallbearers are listed. This generally indicates a cremation, not burial. His ashes could be still in an urn, placed with his family in Hallsville, or placed anywhere really. But there was no stone for him at Pleasant Hill as of February 2015.
Added by
Bill T. Whitis
on May 11, 2015 9:18 AM
Bill T. Whitis
RE: Robert & Mattie Newhouse
I was there a few weeks ago in 2015. If he died in 2014, it's doubtful he's there. I walked each row and photographed all markers.
Added by
Bill T. Whitis
on May 10, 2015 8:50 AM
Harry Lender (1896-1960)
moved the photos sd requested...
Added by
on May 10, 2015 5:07 AM
RE: Walter Lamar Scott
Do you know his birth date? Do you live in South Carolina?
Added by
on Apr 11, 2015 7:46 PM
RE: Romaine Pierce Orthwein
I feel quite sure there was NOT a stone for James Busch Orthwein near-by, or I would have added it.
Added by
on Mar 31, 2015 8:27 PM
Deleon Todd
Mabon (Teenie) Hodges
Thanks Chuck for the burial info. I've updated the memorial accordingly.
Added by
Deleon Todd
on Feb 20, 2015 9:23 AM
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> Parks and Rec Home > Things To Do > Sports > Health and Wellness > Healthy Minds Healthy Bodies
Healthy Minds Healthy Bodies
ATTENTION: All returning military service veterans
The Maryland-National Capital Park and Planning Commission (M-NCPPC) recognizes the challenges faced by veterans returning home with a disability. To help meet your wellness needs, the Prince George's County Department of Parks and Recreation has a unique program, Healthy Minds Healthy Bodies, free-of-charge to qualified veterans.
Are you Eligible?


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Western States Endurance Run: 100 Miles of Prestige (and Running)
- By Scott
- June 26, 2014
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Claiming one's self as the most prestigious anything is a bold statement. It's one that comes with the risk of backlash if expectations are left unmet. It generally takes years … Continue Reading →


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Home > News > Steeling ourselves for innovation
January 4th, 2004
Steeling ourselves for innovation
In 1989, Bethlehem Steel was voted one of the best-managed companies in the United States. Twelve years later it went bankrupt, and in 2002, in an event as ironic as it was symbolic, the Smithsonian Institution bought the Bethlehem steel plant to convert it into the National Museum of Industrial History. The story serves as a poignant reminder that the relentless forces of technology and competition threaten even the most formidable of businesses. The story also holds particular relevance for Minnesota because companies as diverse as Lawson, Medtronic, St. Jude's, Seagate Technologies, Imation and Xcel Energy might be rendered obsolete by exponential technological advances.
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Whats your best Gluten free recipe(11 Posts)
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text: What a truely smashing place Chez Robert is/was. We were able to park the car at the top of a short flight of steps leading directly to the chalet. Nice patio area outside the door (we had some lovely hot days even though it was Feb) Views were great from the large lounge windows which lead out to the balcony. The bedrooms were downstairs. Kitchen was large enough and well equiped. Only down side with the kitchen was all instructions were Dutch (Ductch owned chalet!) Not to far to walk along the road to the lift area.... last 50m up a steepish slope though! We enjoyed our stay at Chez Robert and would reccommend it for a family or small group like usmore


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Are you Motohisa Akiyama?Claim your profile
Publications (27)102.31 Total impact
Article: [A case of a patient with splenic arteriovenous fistula associated with portal hypertension who developed refractory ascites and diarrhea as initial symptom][Show abstract] [Hide abstract]
ABSTRACT: A 55-year-old woman was admitted to our hospital because of diverse symptoms of portal hypertension, such as refractory ascites, diarrhea, and general malaise. Blood test revealed liver and renal dysfunction and glucose tolerance. Contrast enhancement computed tomography revealed splenic arteriovenous fistula with dilated splenic artery and vein, causing portal hypertension. The splenic arteriovenous fistula was successfully treated by percutaneous transarterial embolization, resulting in the complete recovery of the patient. Herein, we report a case of arteriovenous fistula which was successfully treated with the aid of interventional radiology.
Article: The significance of hepatitis B virus core-related antigen and covalently closed circular DNA levels as markers of HBV re-infection after liver transplantation.[Show abstract] [Hide abstract]
ABSTRACT: Background and aim: Currently, hepatitis B virus (HBV) re-infection after liver transplantation (LT) can be almost completely suppressed by the administration of HBV reverse transcriptase inhibitors and hepatitis B immunoglobulins. However, after transplantation, there is no indicator of HBV replication because tests for the serum hepatitis B surface antigen and HBV-DNA are both negative. Therefore, the criteria for reducing and discontinuing these precautions are unclear. In this study, we examined the serum HBV core-related antigen (HBcrAg) and intrahepatic covalently closed circular DNA (cccDNA) in order to determine if these could be useful markers for HBV re-infection. Methods: Thirty-one patients underwent LT for HBV-related liver disease at Nagasaki University Hospital from 2001 to 2010. Of these, 20 cases were followed up for more than 1 year (median follow-up period, 903 days). We measured serum HBcrAg and intrahepatic cccDNA levels in liver tissue. In addition, in nine cases, we assessed the serial changes of HBcrAg and intrahepatic cccDNA levels from preoperative periods to stable periods. Results: We examined serum HBcrAg and intrahepatic cccDNA levels in 20 patients (35 samples). HBcrAg and cccDNA levels were significantly correlated with each other (r = 0.616, P < 0.001). From a clinical aspect, the fibrosis stage was significantly lower in both HBcrAg- and cccDNA-negative patients than in HBcrAg- or cccDNA-positive patients. Conclusions: HBcrAg and cccDNA were useful as HBV re-infection markers after LT. Keeping patients' HBcrAg and cccDNA negative after LT might contribute to long-term graft survival.
Article: Branched-chain amino acid deficiency stabilizes insulin-induced vascular endothelial growth factor mRNA in hepatocellular carcinoma cells[Show abstract] [Hide abstract]
ABSTRACT: Abnormal sugar metabolism is closely related to chronic liver diseases, including hepatocellular carcinoma (HCC). We previously reported that fasting hyperinsulinemia is a poor prognostic factor for HCC patients. A recent large-scale study has shown that long-term administration of branched chain amino acids (BCAA) reduces the risk of HCC development in obese cirrhotic patients who have been diagnosed with diabetes mellitus, although the mechanism by which it does so is unclear. In this study, we analyzed the expression of vascular endothelial growth factor (VEGF) in HepG2 cells under high-insulin culture conditions, and examined the effect of BCAA on VEGF expression. VEGF secretion was significantly increased by 200 nM of insulin under BCAA deficient conditions, but it was repressed by the addition of BCAA. BCAA activated the mTOR pathway and increase HIF-1α expression under high-insulin culture conditions, however quantitative PCR analysis showed that insulin-induced expression of VEGF mRNAs (VEGF121 and VEGF165) decreased 2 h after the addition of BCAA. The half-lives of both VEGF121 and 165 mRNAs were shortened in the presence of BCAA compared to the absence of BCAA. Therefore it is thought that BCAA regulate VEGF expression mainly at the post-transcriptional level. We also examined which of the Valine, Leucine, and Isoleucine components of BCAA were essential for VEGF mRNA degradation. All three BCAA components were required for acceleration of insulin-induced VEGF mRNA degradation. These results suggest that administration of BCAA may downregulate VEGF expression in patients who have hyperinsulinemia and are in the process of developing HCC.
Article: Geranylgeranylacetone has anti-hepatitis C virus activity via activation of mTOR in human hepatoma cells[Show abstract] [Hide abstract]
ABSTRACT: Geranylgeranylacetone (GGA), an isoprenoid compound which includes retinoids, has been used orally as an anti-ulcer drug in Japan. GGA acts as a potent inducer of anti-viral gene expression by stimulating ISGF3 formation in human hepatoma cells. This drug has few side effects and reinforces the effect of IFN when administered in combination with peg-IFN and ribavirin. This study verified the anti-HCV activity of GGA in a replicon system. In addition, mechanisms of anti-HCV activity were examined in the replicon cells. OR6 cells stably harboring the full-length genotype 1 replicon containing the Renilla luciferase gene, ORN/C-5B/KE, were used to examine the influence of the anti-HCV effect of GGA. After treatment, the cells were harvested with Renilla lysis reagent and then subjected to a luciferase assay according to the manufacturer's protocol. The results showed that GGA had anti-HCV activity. GGA induced anti-HCV replicon activity in a time- and dose-dependent manner. GGA did not activate the tyrosine 701 and serine 727 on STAT-1, and did not induce HSP-70 in OR6 cells. The anti-HCV effect depended on the GGA induced mTOR activity, not STAT-1 activity and PKR. An additive effect was observed with a combination of IFN and GGA. GGA has mTOR dependent anti-HCV activity. There is a possibility that the GGA anti-HCV activity can be complimented by IFN. It will be necessary to examine the clinical effectiveness of the combination of GGA and IFN for HCV patients in the future.
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ABSTRACT: The mammalian target of rapamycin (mTOR) is one of the influential molecules for the anti-hepatitis C virus (HCV) action of interferon (IFN). IFN-induced mTOR activity, independent of phosphatidylinositol-3-kinase (PI3K) and Akt, is a critical factor for anti-HCV activity. mTOR activity is involved in signal transducers and activators of transcription (STAT)-1 phosphorylation and nuclear localization, and then double-stranded RNA-dependent protein kinase (PKR) is expressed in hepatocytes. Insulin (INS) is a major cytokine for metabolism and regulates the PI3K-Akt-mTOR signaling pathway in hepatocytes. Changes in mTOR activity have been reported in chronic HCV-infected patients with excess nutrition and INS resistance. Therefore, this experiment investigated whether INS increases anti-HCV activity via mTOR activity. This study used a genome-length HCV RNA (strain O of genotype 1b) replicon reporter system (OR6), derived from HuH7 cells. OR6 cells were pre-treated with rapamycin or LY294002 or siRNA, and the cells were treated with INS (0-300 nmol/l) or IFN (0-50 IU/ml) for 30 min to 48 h. The cells were lysed and analyses were carried out using the Renilla luciferase assay, western blotting or ELISA. INS induced the anti-HCV effects via mTOR activity, independently of STAT-1 tyrosine phosphorylation, in a dose- and time-dependent manner. INS-induced mTOR activation was found to be PI3K-Akt-dependent in OR6 cells. The combination of IFN and INS had an additive anti-HCV effect. The INS-induced mTOR activity was identified to be an anti-HCV signal independent of the STAT pathway in this study. mTOR activity may be associated with the HCV life cycle. Future studies should, therefore, attempt to identify new agents that activate mTOR to promote anti-HCV activity.
Article: Differences in prognostic factors according to viral status in patients with hepatocellular carcinoma[Show abstract] [Hide abstract]
ABSTRACT: The number and ratio of both HBsAg- and HCV Ab-negative hepatocellular carcinoma (HCC-nonBC) cases have been steadily increasing in Japan. The aim of this study was to examine the frequency of detection of HCC-nonBC by screening methods and to elucidate the clinical characteristics of HCC-nonBC compared with those of hepatitis C and/or B virus-associated HCC (HCC-virus). We recruited 624 patients with HCC who were diagnosed between 1982 and 2007 at the Department of Gastroenterology and Hepatology, Nagasaki University Hospital. They were categorized into 2 groups as follows: i) 550 were included in the HCC-virus group: positive for HBsAg and/or positive for HCV Ab, and ii) 74 were included in the HCC-nonBC group: negative for both HBsAg and HCV Ab. The follow-up patterns until the initial detection of HCC and the survival rates were analyzed and compared between the 2 groups. Multivariate analysis identified follow-up, alcohol consumption, albumin level, total bilirubin level, alpha-fetoprotein (AFP) level, and tumor-node-metastasis (TNM) stage as independent and significant risk factors for prognosis. Among the 397 patients with HCC in TNM stage I or II, multivariate analysis identified the cause of liver disease, gender, Child-Pugh score, serum albumin level and TNM stage as independent and significant risk factors for prognosis. We reported that the poor prognoses of patients with HCC-nonBC were attributable to its late detection in an advanced condition due to the absence of a surveillance system for the early detection of HCC. However, in early-stage patients, patients with HCC-nonBC showed significantly better prognosis than those in the HCC-virus group.
Article: Relationship between Regulatory T Cells and the Combination of Pegylated Interferon and Ribavirin for the Treatment of Chronic Hepatitis Type C[Show abstract] [Hide abstract]
ABSTRACT: The frequency of regulatory T cells (Tregs) may be related to persistent hepatitis C virus (HCV) infection. We studied the alteration of the Treg ratio in peripheral blood mononuclear cells (PBMCs) from chronic hepatitis C patients during combination therapy compared with the Treg ratio in liver-infiltrating lymphocytes (LILs) before therapy. The study group consisted of 20 patients who were treatment-naive and had high virus titers of HCV genotype 1. Blood samples were collected prior to treatment and at several time points during treatment. All patients received a liver biopsy prior to treatment. Forkhead box P3 (Foxp3)+, CD3+, CD4+ and CD8+ cells in PBMCs and LILs were stained by specific antibodies. Ten patients had a sustained virological response (SVR), and 10 patients were non-responders. The SVR group had a significant increase in the Foxp3+/CD4+ ratio in PBMCs at 8 and 12 weeks as well as a significant decrease in the Foxp3+/CD4+ ratio and increase in the CD8+/Foxp3+ ratio in LILs. The evaluation of Tregs, a potentially significant factor for persistent HCV infection, in LILs prior to treatment and in PBMCs during treatment could predict the result of combination therapy.
Article: 483 THE SIGNIFICANCE OF HEPATITIS B VIRUS CORE-RELATED ANTIGEN AND COVALENTLY CLOSED CIRCULAR DNA AS HBV REINFECTION MARKERS AFTER LIVER TRANSPLANTATION
Article: The level of fasting serum insulin, but not adiponectin, is associated with the prognosis of early stage hepatocellular carcinoma[Show abstract] [Hide abstract]
ABSTRACT: Impaired glucose tolerance influences the prognosis of hepatocellular carcinoma (HCC), but this mechanism is still not fully understood. We investigated the impact of the fasting serum levels of insulin and adiponectin on the prognosis of HCC and its recurrence. One hundred and forty patients with newly diagnosed HCC were enrolled in the prognosis study. Their fasting serum levels of insulin and adiponectin were determined. Of 140 patients, 59 patients who underwent curative treatment were subjected to analysis of the recurrence-free survival. The 140 patients were divided into two groups by the 50th percentile value of insulin (7.73 microIU/ ml) or total adiponectin (6.95 microg/ml). Kaplan-Meier analysis indicated that high insulin group (>7.73 microIU/ml) exhibited a significantly poorer prognosis than low insulin group (<7.73 microIU/ml) in early stage HCC (P=0.018). In contrast, the level of total adiponectin had no impact on the prognosis of HCC. Multivariate analysis indicated that fasting hyper-insulinemia was an independent risk factor for a poorer prognosis in early stage HCC (P=0.044). Likewise, Kaplan-Meier analysis indicated that the recurrence-free survival of high insulin group was significantly lower than that of low insulin group (P=0.017). The level of total adiponectin had no impact on the recurrence-free survival of HCC. Multivariate analysis indicated that fasting hyperinsulinemia was an independent risk factor for the lower recurrence-free survival of HCC (P=0.049). In conclusion, our study suggests that the fasting insulin level affects the clinical course of early stage HCC.
Article: Clinical Outcomes of Endoscopic Submucosal Dissection for Early Gastric Cancer by Indication Criteria[Show abstract] [Hide abstract]
ABSTRACT: Endoscopic submucosal dissection (ESD) can remove early gastric cancer (EGC) en bloc. We sought to assess the feasibility and efficacy of ESD and the clinical outcomes based on the indication criteria. 551 patients with 589 EGC lesions were divided into the guideline criteria group (elevated lesion < or =20 mm in diameter and depressed lesion < or =10 mm without ulceration) and the expanded criteria group (mucosal cancer without ulcer findings irrespective of tumor size; mucosal cancer with ulcer findings < or =3 cm in diameter; and minute submucosal invasive cancer < or =3 cm in size). En bloc, complete and curative resection were achieved in 98.6 and 93.0, 95.1 and 88.5, and 97.1 and 91.1%, for the guideline and expanded criteria lesions, respectively; the differences between the 2 groups were significant for each. The expanded criteria lesions were at significantly higher risk of ESD-associated bleeding and perforation. Overall survival was adequate irrespective of the indications, and the disease-specific survival rates were 100% in both. ESD for EGCs that met the expanded criteria was acceptable, though the resection rates and safety were decreased compared to those for the guideline criteria lesions.
Article: Predictive value of suppressor of cytokine signal 3 (SOCS3) in the outcome of interferon therapy in chronic hepatitis C[Show abstract] [Hide abstract]
ABSTRACT: Aims: Suppressor of cytokine signaling 3 (SOCS3) can suppress Janus kinase (JAK)-signal transducers and activators of transcription (STAT) signaling by blocking an IFN-induced protein. In this study, the relationship between SOCS3 and phosphorylation of STAT1 in the liver and outcome of interferon therapy were examined. Methods: Prior to interferon treatment, we immunostained for SOCS3 and phosphorylated-STAT1 (P-STAT1) in 59 liver specimens from chronic hepatitis C virus (CHC) patients and compared the expression of SOCS3 and clinicopathological factors. Fifty-one patients were receiving peg-interferon alpha-2b and ribavirin therapy and also compared interferon therapy effect and the expression of SOCS3. Results: Immunostaining for SOCS3 was mainly seen in the periportal area. The concentration of P-STAT1 nuclei was significantly larger in specimens with < 30% area immunostaining to SOCS3 than those in which this area was ≥ 30% (10.6 ± 8.8 vs. 4.6 ± 6.1, P = 0.004). SOCS3 immunostaining score was significantly correlated with aspartate amino transferase (r = 0.373, P = 0.003), alanine amino transferase (r = 0.337, P = 0.008), platelets (r = −0.273, P = 0.037), and homeostatic model assessment (r = 0.339, P = 0.008). On univariate analysis and multivariate analysis, SOCS3 immunostaining score (0 or 1) and age (<60 years old) were significant predictors of interferon response (odds ratio 10.888; P = 0.010; odds ratio 3.817, P = 0.045 respectively). Conclusion: SOCS3 expression in the liver prior to interferon therapy was correlated with increased insulin resistance and might be a useful predictor of HCV clearance by interferon therapy.
Article: Hepatitis C virus kinetics during the first phase of pegylated interferon-α-2b with ribavirin therapy in patients with living donor liver transplantation[Show abstract] [Hide abstract]
ABSTRACT: Aim: To identify the problems of pegylated interferon (PEG IFN) with ribavirin therapy against hepatitis C virus (HCV) reinfection in living donor liver transplantation (LDLT) patients. HCV kinetics during the PEG IFN with ribavirin therapy were analyzed in LDLT patients, as well as in chronic hepatitis C (CHC) patients. Methods: The study included 80 consecutive HCV infected patients undergoing PEG IFN with ribavirin therapy (64 CHC and 16 LDLT patients) who attended the Nagasaki University Hospital for an initial visit between January 2005 and December 2007. Results: The sustained viral response (VR) rate of the CHC group (80%) was superior to the LDLT group (22%). The viral disappearance rate of the CHC group was also superior to the LDLT group, regardless of the HCV serotype. The HCV core antigen (cAg) titer under treatment in the LDLT group was more than that of the CHC group from day 0 to week 12. The HCV cAg decrease rate of the LDLT group on the first day of treatment was less than that of the CHC group. Conclusion: The HCV infection of a transplanted liver is more refractory to treatment than a non-transplanted liver. The low reduction HCV cAg rate on day 1 is one of the problems of the combination therapy.
Article: Portal hypertensive gastropathy with portal thrombosis successfully treated with partial splenic embolization[Show abstract] [Hide abstract]
ABSTRACT: A 60-year-old man with alcoholic liver cirrhosis was admitted to our hospital with severe anemia and tarry stool. Upper gastrointestinal endoscopy revealed grade4 esophageal varices without bleeding and severe portal hypertensive gastropathy (PHG) of the fornix of the stomach with oozing. These findings suggested that PHG was the cause of progression of anemia. Abdominal computed tomography demonstrated no enhancement of the main portal vein and its first branches, indicating portal thrombosis and cavernous transformation. The patient underwent partial splenic embolization (PSE) to reduce portal hypertension. Two months after PSE was performed, upper gastrointestinal endoscopy showed improvement of PHG and endoscopic variceal ligation was performed to treat the esophageal varices. Contrast-enhanced CT revealed partial enhancement of the main portal vein indicating improvement of portal thrombosis. One year after PSE, hemoglobin had increased from 6.0 to 11.0g/dl without blood transfusion. Moreover, albumin level had risen from 2.8 to 3.7g/dl, cholinesterase from 51 to 150IU/l, and prothrombin time from 47% to 66%. PSE can be an effective alternative for the management of severe PHG with portal vein thrombosis, and it might also be effective in improving liver function.
Article: Interferon-α-induced mTOR activation is an anti-hepatitis C virus signal via the phosphatidylinositol 3-kinase-Akt-independent pathway[Show abstract] [Hide abstract]
ABSTRACT: The interferon-induced Jak-STAT signal alone is not sufficient to explain all the biological effects of IFN. The PI3-K pathways have emerged as a critical additional component of IFN-induced signaling. This study attempted to clarify that relationship between IFN-induced PI3-K-Akt-mTOR activity and anti-viral action. When the human normal hepatocyte derived cell line was treated with rapamycin (rapa) before accretion of IFN-alpha, tyrosine phosphorylation of STAT-1 was diminished. Pretreatment of rapa had an inhibitory effect on the IFN-alpha-induced expression of PKR and p48 in a dose dependent manner. Rapa inhibited the IFN-alpha inducible IFN-stimulated regulatory element luciferase activity in a dose-dependent manner. However, wortmannin, LY294002 and Akt inhibitor did not influence IFN-alpha inducible luciferase activity. To examine the effect of PI3-K-Akt-mTOR on the anti-HCV action of IFN-alpha, the full-length HCV replication system, OR6 cells were used. The pretreatment of rapa attenuated its anti-HCV replication effect in comparison to IFN-alpha alone, whereas the pretreatment with PI3-K inhibitors, wortmannin and LY294002 and Akt inhibitor did not influence IFN-induced anti-HCV replication. IFN-induced mTOR activity, independent of PI3K and Akt, is the critical factor for its anti-HCV activity. Jak independent mTOR activity involved STAT-1 phosphorylation and nuclear location, and then PKR is expressed in hepatocytes.
Article: Clinical outcomes of endoscopic submucosal dissection in elderly patients with early gastric cancer[Show abstract] [Hide abstract]
ABSTRACT: Endoscopic submucosal dissection (ESD) has advantages over conventional endoscopic mucosa resection. The number of elderly patients (more than 75 years old) with early gastric cancer (EGC) has been steadily increasing. We sought to assess clinical outcomes of ESD for EGC in elderly. ESD was performed for patients with EGC, who fulfilled the criteria for ESD: mucosal cancer without ulcer findings irrespective of tumor size; mucosal cancer with ulcer findings 3 cm or less in diameter; and minute submucosal invasive cancer 3 cm or less in size. Two hundred and sixty elderly patients (> or =75 years old) with 279 lesions, and 401 non-elderly patients with 434 lesions were enrolled to this study. The patients underwent ESD and then received periodic endoscopic follow-up and metastatic surveys for 6-89 months (median: 30 months). Resectability (en-bloc or piecemeal resection), curability (curative or noncurative resection), completeness (complete or incomplete resection), complications, and survival rates were assessed. The one-piece resection rate was significantly lower in elderly patients (93.9%) than in non-elderly patients (97.9%). The complete resection rate was significantly lower in elderly patients (87.4%) than in non-elderly patients (96.6%). Pneumonia, but not bleeding or perforation, developed in association with ESD more frequently in the elderly patients by 2.2%. Local tumor recurrence was quite rare, and the overall and disease-free survival rates were acceptable irrespective of age. En-bloc and complete resections were achieved less frequently in elderly patients, but the long-term outcomes in elderly EGC patients may be excellent, and ESD is a feasible treatment in the elderly.
Article: Factors related to the curability of early gastric cancer with endoscopic submucosal dissection[Show abstract] [Hide abstract]
ABSTRACT: Endoscopic submucosal dissection (ESD) yields substantially high rates for curative resection of early gastric cancer (EGC). It is suggested that larger, ulcerative, or upper EGCs may prevent successful ESD. A detailed analysis of factors associated with the curability of ESD was performed. Endoscopic submucosal dissection was performed for patients with EGC that fulfilled the expanded criteria, which specified mucosal cancer without ulcer findings irrespective of tumor size, mucosal cancer with ulcers 3 cm in diameter or smaller, and minute submucosal invasive cancer 3 cm or smaller. Resectability (en bloc or by piecemeal resection), curability (curative or non-curative), and complications were assessed, and logistic regression analysis was used to analyze the related factors. Ulcerative EGCs showed a significantly higher risk associated with ESD on multivariate analysis. When the risk factors (tumor size, location, and ulcer findings) were combined, the larger EGCs (>30 mm) located in the upper third or ulcerative tumors located in the upper and middle portion of the stomach were at significantly higher risk of non-curative resection. Such lesions also were associated with increased risk of procedure-related perforation. When risk factors including positive ulcer findings and larger size and upper location of tumors are combined, ESD should be performed more carefully.
Article: A snack enriched with oral branched-chain amino acids prevents a fall in albumin in patients with liver cirrhosis undergoing chemoembolization for hepatocellular carcinoma[Show abstract] [Hide abstract]
ABSTRACT: Nutritional support may play an important role in management of liver cirrhosis (LC) associated with unresectable hepatocellular carcinoma (HCC). Total protein and albumin deteriorate in patients with LC undergoing trans-arterial chemoembolization (TACE). Therefore, in this study, we examined the hypothesis that short-term administration of branched-chain amino acids (BCAA) will prevent a fall in total protein and albumin in the perioperative period. The subjects were 56 patients who underwent TACE for HCC between 2004 and 2005 at Nagasaki University Hospital. The patients were randomly placed in the BCAA group (n = 28) or a control group (n = 28). The patients in the BCAA group consumed a snack containing 50 g of BCAA once a day at 10:00 pm starting 1 day before TACE and continuing until 2 weeks after TACE. A comparison of baseline and end point data showed greater decreases in the concentrations of total protein, albumin, cholinesterase, and total cholesterol and in the red blood cell count in the control group compared to the BCAA group. Ammonia levels decreased in the BCAA group and increased in the control group. Our findings indicate that a BCAA supplement taken orally as a late evening snack prevents suppression of liver function by TACE in patients with LC complicated with HCC during the 2-week period after TACE.
Article: A case of PBC-AIH overlap syndrome who developed AIH 8 years after diagnosis of typical PBC
Article: Effect of short-term oral branched chain amino acids enriched snack in the patients complicated with liver cirrhosis undergoing trans-arterial chemoembolization for hepatocellular carcinoma
Top Journals
Nagasaki University
Nagasaki, Nagasaki, Japan
- • Department of Gastroenterology and Hepatology
- • Graduate School of Biomedical Sciences
Nagasaki University HospitalNagasaki, Nagasaki, Japan


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Article: Phosphorylcholine-Coated Circuits Improve Preservation of Platelet Count and Reduce Expression of Proinflammatory Cytokines in CABG: A Prospective Randomized Trial[Show abstract] [Hide abstract]
ABSTRACT: The interaction of blood with foreign artificial surfaces during cardiopulmonary bypass (CPB) has been recognized as a major stimulus in evoking a systemic inflammatory and metabolic response. Phosphorylcholine (PC) is a new-generation coating material designed to ameliorate biocompatibility and thereby to reduce the detrimental interactions of CPB. We studied the effects of PC-coated perfusion circuits on platelet function and the humoral and cellular response to CPB. Thirty patients undergoing coronary artery bypass grafting were randomized to PC-coated (PC group, n = 15) and noncoated (control group, n = 15) circuit groups. Clinical data, total blood loss, and pre- and postoperative platelet counts were recorded and IL-6 and TNF-alpha, CD41a, CD42b, and CD62p were measured at induction of anesthesia, after the initiation of CPB and at termination of CPB. There was a significantly improved preservation of platelet count following CPB in the PC group (p = 0.028), which was sustained over a period of 72 hours. The use of PC-coated circuits further resulted in a significant attenuation of TNF-alpha and IL-6 expression (p < 0.05 and p < 0.01); however, we were unable to detect any differences in clinical outcomes. Despite similar clinical outcome, the obvious reduction of cytokine expression and improved preservation of platelet count suggest superior biocompatibility of PC-coated circuits.
Article: A Comparative Analysis of Outcome after Heart Transplantation in Patients Aged 60 Years and Older:. The University of Alberta Experience[Show abstract] [Hide abstract]
ABSTRACT: The Registry of the International Society for Heart and Lung Transplantation (ISHLT) 2001 Annual Report indicated that the vast majority of heart transplant recipients are between 50 and 64 years of age. However, patient age beyond 60 years may have higher long-term mortality compared to younger patients. The purpose of this study was to compare short- and intermediate-term results including rates of acute rejection, transplant coronary artery disease, infections, malignancy, and mortality in cardiac transplant recipients 60 years or older with those below the age of 60 years. We retrospectively analyzed the results of 50 patients aged 60 years and older who underwent heart transplantation at the University of Alberta from January 1990 to December 2000 and compared them with the results of 225 younger patients undergoing heart transplantation in the same time period. The older and younger groups had similar rates for treated acute rejection episodes (20.0% vs. 12.6%), transplant coronary artery disease (4.0% vs. 1.1%), and mortality (10.5% vs. 14.3%), respectively. No differences were noted with regards to quality and quantity of infection or malignancy rates. Five-year actuarial survival between the older and younger patients was also comparable at 89.5% vs.86.9% (p > 0.05). Heart transplantation in patients 60 years of age and older can be performed as successfully as in younger patients (< 60 years) with comparable morbidity and mortality, suggesting that patient age per se should not be an exclusion criterion for heart transplantation.
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University of Alberta
Edmonton, Alberta, Canada
- Division of Cardiac Surgery


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New Orleans Jazz Fest 2016 lineup: Neil Young, Paul Simon, Stevie Wonder, Van Morrison, RHCP, Pearl Jam, Snoop Dogg, more
New Orleans Jazz & Heritage Festival returns this year from April 24-May 3 with a pretty amazing lineup that includes Stevie Wonder, Pearl Jam, Red Hot Chili Peppers, Neil Young, Snoop Dogg, Paul Simon, Steely Dan, Beck, Van Morrison, J. Cole, Elvis Costello, My Morning Jacket, Maxwell, Janelle Monae, Herbie Hancock & Wayne Shorter, Dr. John, Arlo Guthrie, Mavis Staples, Lauryn Hill, Buddy Guy, The Isley Brothers, Sharon Jones, Hurray for the Riff Raff, Buffy Sainte-Marie, Big Freedia and much more. Check out the full lineup here.
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FFF Fest day 3 in pics: Lauryn Hill, Future Islands, Big Freedia, Off!, Power Trip, Venom, Doomtree & more
photos by Chad Wadsworth, Clair Taus, Dave Mead, Greg Giannukos, Jackie Young, Pooneh Ghana, Reagan Hackleman, & Roger Ho
Future Islands / Big Freedia / L7 / Lauryn Hill / Off! @ FFF Fest 11/8/2015
We expected the worst, and received the best. Ms. Hill arrived on time, began her set as scheduled, and played music without the crazy socio-political commentary. She looked extra comfortable sitting on a couch with the Austin skyline as her backdrop, playing the guitar and passionately motioning to her band to keep up with her energy. The horns, rhythm section, and back-up singers sounded like a hip hop symphony as they played complement to Lauryn's lyrics and soulful voice. The highlight of the night, at least to me, was "The Mystery of Iniquity", which is the track sampled by Kanye West on "All Falls Down". Simply magical! - [Houston Free Press]After a rainy Saturday, Austin's Fun Fun Fun Fest saw the sunshine on its final day which featured sets from Lauryn Hill (a last-minute sub for D'Angelo), Future Islands, L7, Venom, Off!, Dag Nasty, Big Freedia, Doomtree, Power Trip and lots more.
Pictures from FFF day 1 are HERE and day 2 are HERE. More from day 3, below...
Continue reading "FFF Fest day 3 in pics: Lauryn Hill, Future Islands, Big Freedia, Off!, Power Trip, Venom, Doomtree & more"
Queen of bounce Big Freedia is going on what she's calling "Big Freedia Presents: Bounce Shakedown Tour 2015" this fall. It kicks off in Raleigh in early October and ends in Denver the next month. Hibou and Boyfriend will support.
The tour hits NYC on October 30 at Irving Plaza. Tickets for that show are on Citi cardmember presale now. Live Nation/Ticketmaster/VIP presales start Wednesday (9/9) at 10 AM and the general on-sale starts Friday (9/11) at 10 AM.
Big Freedia: Queen of Bounce Season 4 premieres on September 30 on Fuse, and Freedia will release a new single called "Crazy" on 9/18.
All tour dates are listed, with a video, below...
Afropunk adds Death Grips, Gary Clark Jr, Kelela, Candiria and more to NYC lineup, announces Atlanta festival
The lineup for Brooklyn's 2015 Afropunk Festival was already pretty great, and now it got even better. Death Grips, Gary Clark Jr., Kelela, Jessie Boykins III, SZA, Candiria and more were added to the festival, which already included Lenny Kravitz, Grace Jones, Lauryn Hill, Kelis, Danny Brown, Suicidal Tendencies, Kele, Thundercat and more.
This year also marks the first Afropunk Fancy Dress Ball, hosted by Grace Jones, Cakes Da Killa and MikeQ, proceeds from which will go toward the Afropunk Global Initiative. The party goes down August 21 at Commodore Barry Park, just ahead of the festival, which happens August 22-23 in the same park. Tickets for the ball are on sale now, and festival passes are still available.
Afropunk also continues to branch out. They did an Afropunk Paris festival this past May, and will do so again in June 2016, and they're also putting on the inaugural Afropunk Atlanta on October 3 & 4 in the city's Central Park. The lineup for that includes D'Angelo and the Vanguard, Flying Lotus, Santigold, Death Grips, Tyler the Creator, Public Enemy and more. Tickets go on sale Wednesday (7/8).
Speaking of Death Grips, they play NYC twice this week (supposedly, at least).
Full Afropunk Atlanta lineup and updated Brooklyn lineup, below...
Continue reading "Afropunk adds Death Grips, Gary Clark Jr, Kelela, Candiria and more to NYC lineup, announces Atlanta festival"
Tenacious D's Festival Supreme announces 2015 lineup: MST3K reunion, Kids in the Hall, RFTC, The Darkness & more
Festival Supreme, the music/comedy fest put on by 2015 Best Metal Album Grammy winners Tenacious D, will return for its third year this fall, happening at Los Angeles' Shrine Expo Hall & Grounds on October 10. The lineup is pretty supreme indeed, including Kids in the Hall, Rocket from the Crypt, the original cast of Mystery Science Theatre 3000, The Darkness, Die Antwoord, Jenny Slate, Amy Poehler, Super Dave Osborne, Neil Hamburger, Dan Deacon, Andrew WK and lots more.
Tickets go on sale to the general public on Thursday (6/11) at noon PDT, with a Festival Supreme website presale beginning Tuesday (6/9) at 10 AM PDT (password: SUPREME). Full 2015 Festival Supreme lineup is listed below...
Continue reading "Tenacious D's Festival Supreme announces 2015 lineup: MST3K reunion, Kids in the Hall, RFTC, The Darkness & more"
Fun Fun Fun Fest 2015 lineup: Jane's Addiction, D'Angelo, L7, NOFX, Wu-Tang, Venom, Ride, American Football, American Nightmare, Converge, Charlatans, Dag Nasty, MANY more
Austin's annual Fun Fun Fun Fest returns in 2015 from November 6-8 at Auditorium Shores, and as usual the lineup is amazing. There's Jane's Addiction (performing Ritual de lo habitual), Gogol Bordello (performing Gypsy Punks), The Dwarves (performing Blood, Guts & Pussy), the first-ever Texas show and only US show of 2015 for '80s metal legends Venom, a reunion from DC hardcore vets Dag Nasty, Yeah Yeah Yeahs/Blood Brothers/Locust side project Head Wound City, D'Angelo, NOFX, American Football, Ride, The Charlatans (UK), Wu-Tang Clan, Schoolboy Q, Grimes, Cheap Trick, Drive Like Jehu, L7, Babes In Toyland, American Nightmare, Converge, Chain of Strength, Desaparecidos, Skinny Puppy, Afrika Bambaataa, Future Islands, Fucked Up, Neon Indian, Hudson Mohawke, Joey Bada$$, Alvvays, Speedy Ortiz, Parquet Courts, Power Trip, La Dispute, Title Fight, Shamir, Mikal Cronin, Viet Cong and many more.
Tickets go on sale today (5/28) at 10 AM CT (11 AM EST). Full lineup and announcement video below.
The lineup for the Dag Nasty reunion is the same one they played the Salad Days show in DC with in 2012: original vocalist Shawn Brown, plus Brian Baker, Roger Marbury and Colin Sears.
Continue reading "Fun Fun Fun Fest 2015 lineup: Jane's Addiction, D'Angelo, L7, NOFX, Wu-Tang, Venom, Ride, American Football, American Nightmare, Converge, Charlatans, Dag Nasty, MANY more"
A$AP Ferg made two star-studded videos; A$AP Mob mems playing NYC show on Sunday; Rocky playing Buku Fest
photo: A$AP Ferg in Queens in 2014 (more by Gretchen Robinette)
Late last year, A$AP Ferg returned with the new mixtape Ferg Forever, a nice tide-over while we wait for the followup to his excellent Trap Lord. In the past week, he's dropped videos for two of that mixtape's tracks. The first was for "Doe-Active," directed by Spike Jordan and featuring a cameo from Vampire Weekend's Ezra Koenig, and the second was for "Dope Walk," directed by Matt Starr and featuring appearances by Kanye West, Beyonce, A$AP Rocky, Big Sean, Haim, Rihanna and Justin Bieber. Watch both below.
In related news, this Sunday (3/1) at Brooklyn Night Bazaar, A$AP Nast and A$AP Twelvyy will play a
free show presented by DXC/Dunkxchange. At the show, you can buy, sell and trade sneakers and apparel. There will also be performances by GRZLXMODE and GI Dara, and music by DJ Mpure and DJ Rob Cast. Unlike most BKNB shows this one is ticketed ($15 advance, $20 at the door) and the flyer is below.
Ferg also has shows coming up, mostly in Australia and New Zealand, but also a couple US festivals including Pitchfork. All dates are listed below.
A$AP Rocky's also on board for US festival BUKU Music + Art Project happening in New Orleans on March 13 & 14 with Passion Pit, TV on the Radio, Run the Jewels, BADBADNOTGOOD & Ghostface Killah, DJ Windows 98, Die Antwoord, Flosstradamus, RL Grime, Portugal. The Man, Hudson Mohawke, iLoveMakonnen, XXYYXX, Raury, Big Freedia and more. Full lineup here. Tickets are on sale.
Continue reading "A$AP Ferg made two star-studded videos; A$AP Mob mems playing NYC show on Sunday; Rocky playing Buku Fest"
New Orleans Jazz Fest 2015 lineup: Elton John, The Who, No Doubt, Wilco, Ryan Adams, Bennett & Gaga, T.I. & more
New Orleans Jazz Fest, which has much more than just jazz, returns this year for two weeks, April 24-26 and April 30-May 3. The lineup includes Elton John, The Who, Jimmy Buffett, Tony Bennett & Lady Gaga, No Doubt, Pitbull (??), T.I., Chicago, Jerry Lee Lewis, Ryan Adams, Wilco, The Meters, Jimmy Cliff, Buddy Guy, Allen Toussaint, The O'Jays, Dr. John (interpreting Louis Armstrong), Third World, Taj Mahal Trio, Juvenile & Mannie Fresh, The Blind Boys of Alabama, Big Freedia, Galactic ft. Macy Gray, Anders Osborne, Preservation Hall Jazz Band, Sturgill Simpson, Bela Fleck & Abigail Washburn, and more. Tickets go on sale at 10 AM on Tuesday (1/13).
Full lineup below...
Continue reading "New Orleans Jazz Fest 2015 lineup: Elton John, The Who, No Doubt, Wilco, Ryan Adams, Bennett & Gaga, T.I. & more"
Big Freedia at Central Park in September (more by Chris La Putt)
Bounce queen Big Freedia just brought her tour to NYC for a Glasslands show this past weekend (10/4), and she's since expanded it into late November including a return to NYC. She'll be back for a two-night stand at Brooklyn Bowl on Friday November 21 and Saturday November 22, both of which are late shows starting around midnight. No opener for night 1 yet but Quickie Mart will be on night 2. Tickets for both go on sale Thursday (10/9) at 10 AM.
All dates are listed below...
Continue reading "Big Freedia expands tour, playing 2 nights at Brooklyn Bowl"
Chromeo played Summerstage with Big Freedia who's touring this fall, playing Glasslands (pics, dates)
"Chromeo turning Central Park into a dance party rn" - @chelawhita
"Saw @chromeo last night in Central Park. One of the most fun nights I've had in so long! Danced my bum off" - @jaglever
Chromeo / Big Freedia @ Central Park Summerstage 9/12/2014
It was a long wait for Chromeo, but after an agonizing 30 minutes, white lights poured out from the stage in every direction, and with seemingly no transitional moment at all, Dave 1's guitar wailed from between the LEDs. Without warning, the concert was in full swing.Canadian dance-duo Chromeo brought their groove party tour to Central Park Summerstage with some help from New Orleans bounce music pioneer and twerkaholic Big Freedia on Friday (9/12), part of the tour. Playing tracks from this year's White Women and favorites like "Needy Girl," "Bonafide Lovin'" and "Sexy Socialite," plus a stunning light show, the duo certainly got the crowd moving. Pics from the show are in this post.
Dave 1 and P-Thugg are, if you'll excuse the phrase, groove-machines. DJ set or fully live, the two produce a sound that bounces across the stage, through the crowd, and right back to them again, forever fueling a cycle of funky, self-sustaining energy. [Village Voice]
Chromeo recently earned a spot as a short-list nominee for this year's Polaris Prize competition alongside stiff competition from the likes of Arcade Fire, Drake, Mac Demarco and more. The set on Saturday was one of their last of the summer, only hitting Austin City Limits in October before getting off the road for a bit.
Opener Big Freedia, whose Fuse reality series just got picked up for two more seasons, gave a shout out from the Central Park stage to fellow bounce artist Nicky Da B who died earlier this month. NYC will more of Big Freedia on October 4 at Glasslands with Friendly Ghost and a DJ set from Le Chev. Tickets are on sale. In other news, look for Big Freedia's memoirs to be published in 2015.
All Big Freedia tour dates, plus more pics from the Summerstage show, below...
Continue reading "Chromeo played Summerstage with Big Freedia who's touring this fall, playing Glasslands (pics, dates)"
Outside Lands Day 2 pics (Tom Petty, Deer Tick, Haim, The Districts, Valerie June, Soundwave tent & more)
Fest photos by Samantha Saturday, Soundwave photos by Wilson Lee
Deer Tick / Haim / Tom Petty & the Heartbreakers
The best performance of the day, however, came courtesy of Haim. This increasingly popular pop-rock trio, which sold out two nights at the Fillmore in San Francisco in April, was absolutely dynamite onstage, roaring through tunes from the 2013 debut "Days Are Gone." The three sisters -- Alana, Danielle and Este Haim -- exhibited far more musical muscle in the live arena than they have in the studio to date. Danielle Haim, in particular, was a marvel to behold, delivering some of the most passionate, mesmerizing guitar work of the festival. [San Jose Mercury News]Day 2 of Outside Lands in Golden Gate park featured plenty of heavyweights. There were sets from Tom Petty, Death Cab for Cutie, Haim, Local Natives, Deer Tick, Dum Dum Girls and many more. We've got pics from many of the awesome Saturday sets in this post. You can check out pics of Day 1 here.
Big Freedia & Valerie June in the Soundwave Tent
We were also set up in the Toyota Soundwave tent, where we invited a few artists to stop by for stripped down sets, Q&As and more, including Big Freedia, Valerie June (both pictured above), The Districts, Deer Tick and others. More pictures from the Soundwave tent, plus many more of day 2's regular sets, below...
Continue reading "Outside Lands Day 2 pics (Tom Petty, Deer Tick, Haim, The Districts, Valerie June, Soundwave tent & more)"
2014 Voodoo Music Experience lineup (Outkast, Foo Fighters, Arctic Monkeys, Slayer, DFA 1979 & more)
Arctic Monkeys @ Firefly Fest 2014 (more by Dana [distortion] Yavin)
The 2014 Voodoo Music Experience fest happens in New Orleans from October 31 - November 2 and the lineup includes Outkast, Foo Fighters, Arctic Monkeys, Action Bronson, Slayer, DFA 1979, The Melvins, Gogol Bordello, Fishbone, Peelander Z and more. Tickets are on sale now.
Full lineup is listed below....
Continue reading "2014 Voodoo Music Experience lineup (Outkast, Foo Fighters, Arctic Monkeys, Slayer, DFA 1979 & more)"
Chromeo, whose new album White Women is out now (stream it via Rdio), have added a lot more tour dates since the last time we posted. Most of it is on the summer festival circuit, and they've also added another NYC show, playing Central Park Summerstage on September 12 with Big Freedia. Tickets for that show go on Tickemaster presale today (6/11) at 11 AM and AmEx presale today at noon, with the general on-sale starting Friday (6/13) at noon.
All tour dates are listed, along with the video for "Jealous (I Ain't With It)," below...
Continue reading "Chromeo add tour dates, playing Central Park Summerstage with Big Freedia"
Bumbershoot 2014 lineup announced (Replacements, Elvis Costello, Wu-Tang, Afghan Whigs, Danny Brown & more)
The annual Bumbershoot Festival returns in 2014 to Seattle's Seattle Center from August 30 to September 1. The lineup was just announced and includes The Replacements, Wu-Tang Clan, Elvis Costello, Schoolboy Q, Afghan Whigs, The Dismemberment Plan, Nada Surf, Bobby Womack, Danny Brown, Mac DeMarco, Twin Shadow, Big Freedia, Jonathan Richman, Mission of Burma, The Dream Syndicate and many more. Full lineup below.
Tickets, including 3-day passes, any-day passes, and single-day passes, are on sale now. Check out the full day-by-day lineup, with the announcement video, below...
Continue reading "Bumbershoot 2014 lineup announced (Replacements, Elvis Costello, Wu-Tang, Afghan Whigs, Danny Brown & more)"
Outside Lands 2014 lineup: Kanye, Tom Petty, Arctic Monkeys, Flaming Lips, Disclosure, Spoon, Death Cab & more
Outside Lands Festival returns to San Francisco's Golden Gate Park from August 8 - 10. This year's lineup was just announced and includes Kanye West, Tom Petty & the Heartbreakers, Arctic Monkeys, Death Cab for Cutie, Disclosure, The Flaming Lips, Spoon, Haim, Lykke Li, and more.
Tickets go on sale Thursday (4/10) at 10 AM PDT. Full lineup below...
Continue reading "Outside Lands 2014 lineup: Kanye, Tom Petty, Arctic Monkeys, Flaming Lips, Disclosure, Spoon, Death Cab & more"
Sasquatch! 2014 lineups announced (Outkast, Neutral Milk Hotel, Kraftwerk, New Order, QOTSA, The National, Frank Ocean, tUnE-yArDs, Deltron 3030 & WAY more)
Sasquatch! Music Festival is returning for two weekends in 2014 to The Gorge in Quincy, Washington, and the lineups (which are different both weekends) have just been announced. The May lineup (5/23 - 5/25, aka Memorial Day Weekend) includes Outkast, The National, Queens of the Stone Age, M.I.A., Haim, Neko Case, Foals, Cut Copy, Violent Femmes, Elbow, Mogwai, Tyler the Creator, Chance the Rapper, Rudimental, Phantogram, tUnE-yArDs, First Aid Kit, Rodriguez, AlunaGeorge, Panda Bear, Phosphorescent, Bob Mould, Washed Out, Austra, Parquet Courts, Deafheaven, Big Freedia, Liars, Waxahatchee, Tacocat, Princess (feat. Maya Rudolph), Bridget Everett, Eric Andre and more.
The July lineup (7/4 - 7/6, aka Independence Day Weekend) includes Soundgarden, Kraftwerk, New Order, Frank Ocean, Royksopp + Robyn, Neutral Milk Hotel, Spoon, Broken Bells, Tegan & Sara, Local Natives, Gogol Bordello, Rhye, Black Angels, Deltron 3030, The Horrors, Junip, The Notwist, Kurt Vile, Talib Kweli, of Montreal, Action Bronson, Punch Brothers, Sharon Van Etten, Casey Veggies, RL Grime, Fuck Buttons, Courtney Barnett, Cloud Nothings, Foxygen, Palma Violets, Mikal Cronin, Mac DeMarco, Jon Hopkins, Gold Panda, Majical Cloudz, Duke Dumont, Oneohtrix Point Never, Death, Black Prairie, Latryx, Metz, John Grant, Reigning Sound, Young & Sick, Chad VanGaalen, Mutual Benefit, Helms Alee, Demetri Martin, Eugene Mirman, Kurt Braunohler, John Hodgman and more. There will also be fireworks for the 4th of July.
Tickets (including a 2-weekend pass option) go on sale Saturday at 10 AM.
Full lineups for both weekends below...
Continue reading "Sasquatch! 2014 lineups announced (Outkast, Neutral Milk Hotel, Kraftwerk, New Order, QOTSA, The National, Frank Ocean, tUnE-yArDs, Deltron 3030 & WAY more)"
New Orleans Jazz Fest 2014 lineup & tix (Bruce Springsteen, Arcade Fire, Vampire Weekend, Eric Clapton, Phish & more)
The New Orleans Jazz & Heritage Festival is returning this year for two weekends, April 25-27 and May 1-4, at the Fair Grounds Race Course. The lineup was just announced and it includes Bruce Springsteen and the E Street Band, Arcade Fire, Vampire Weekend, Eric Clapton, Public Enemy, Big Freedia, Charles Bradley, Solange, Laura Mvula, Phish, Santana, Alabama Shakes, Robert Plant and the Sensational Space Shifters, Bobby Womack, Allen Toussaint, Bombino and many more. Tickets for both weekends are on sale now. Full lineup below.
This announcement comes the same day as the lineup announcements for NYC's Governors Ball, Georgia's Counterpoint, Atlanta's Shaky Knees Fest, and Alabama's Hangout Fest (and not long after Firefly and Coachella announcements).
Full lineup below...
Continue reading "New Orleans Jazz Fest 2014 lineup & tix (Bruce Springsteen, Arcade Fire, Vampire Weekend, Eric Clapton, Phish & more)"
TPOBPAH at Summerstage in 2012 (more by Chris La Putt)
NYC indie pop band The Pains of Being Pure at Heart have been relatively quiet lately, but it's looking like that's about to change. Frontman Kip Berman has been instagramming guitar pedals lately, which hopefully means they're back in the studio, and Pains have also announced what will be their first hometown show in a while, happening on March 28 at Rough Trade NYC. Tickets for that show go on sale Friday (1/17) at noon.
The band's only other currently announced date is New Orleans festival BUKU Music + Art Project, which happens from March 21-22 and also includes The Flaming Lips, Chromeo, Explosions in the Sky, Tyler the Creator, Pusha T, Schoolboy Q, Baauer b2b RL Grime, Danny Brown, Phantogram, Skream, Wavves, Big Freedia, Thundercat, Cashmere Cat, Blood Diamonds and more. Tickets for that festival are on sale now.
There's also been some changes to Pains' lineup. Keyboardist Peggy Wang recently announced that she left the band in order to focus on her job as a writer at Buzzfeed.
TPOBPAH recently released a belated video for "Belong" off their 2011 LP of the same name, which you can watch below...
Continue reading "The Pains of Being Pure at Heart playing Rough Trade NYC after BUKU Fest (lineup)"
The 2014 SXSW Festival is coming up soon -- March 11 - 16 in Austin, Texas -- and they've just announced the third round of showcasing bands which is a massive update. That includes Mary Timony's Ex Hex (who we just speculated about), Dum Dum Girls, Natural Child, Ratking, Buffalo Daughter, Action Bronson, Perfect Pussy, Nothing, Windhand, Angel Olsen, Sharon Van Etten, Vic Mensa, Deniro Farrar, Roosevelt, Pure Bathing Culture and a whole lot more. Full list of third round bands is listed below.
Continue reading "SXSW 2014 announces third round of showcasing artists"
What's going on Saturday? (Luscious Jackson, Cyndi Lauper, Soupcans, Real Estate, Machinedrum, Rock Lottery & more)
Anna Von Hausswolff at Glasslands in July (more by Amanda Hatfield)
Browse our full NYC show calendar for all of tonight's shows. Here are some highlights...
Luscious Jackson, All Night Chemists, ADW Young @ Webster Hall
Funky '90s band -- and Beastie Boys pals -- Luscious Jackson are back in action with a new album, their first in 14 years. Expect Clinton-era classics like "Naked Eye" too.
Real Estate, Bare Mutants, Free Time, Turnip King @ Baby's All Right
Get a taste of Real Estate's new album tonight at this newish, smallish Williamsburg club. It's actually a great bill all-around, with Chicago's Bare Mutants (featuring members of Ponys and The 1900s), plus Australian ex-pats Free Time and locals Turnip King.
Cyndi Lauper, P!NK, Nelly Furtado, The Hives, Ingrid Michaelson, Matt & Kim, Big Freedia & more @ Beacon Theater
It's Cyndi Lauper's 'Home for the Holidays' show and since girls just wanna have fun, she's invited a huge variety of friends to join her including some pop stars, the always-energetic Hives, and the also always-energetic (but in a much different way) Big Freedia, plus Matt & Kim and many more.
Au Revoir Simone, Spires, Splashh, Grooms @ Brooklyn Night Bazaar
This weekend's Brooklyn Night Bazaar shows are curated by Kanine Records, who offer up a good bill tonight, with sythpop trio Au Revoir Simone, paisley janglers Spires, UK act Splashh (in shrunken form) and noisemakers Grooms.
Chuck Strangers, Fresh Daily (Beat Haus) @ Converse Rubber Tracks
Joey Bada$$ isn't the only talented member of the Pro Era crew. Chuck Strangers is a key member of the group too and you can catch him on his own at Converse Rubber Tracks tonight.
Ballroom, The Soupcans, The Estrogen Highs, Chat Logs, Melk Belly @ Death By Audio
Toronto's The Soupcans make speedy post-hardcore filled with all the anger, sarcasm, and weirdness you need. They're in NYC for two shows this weekend, both of which should get pretty intense. This is the second.
The Deer Tracks, Ice Choir, Late Guest at the Party @ Glasslands
Swedish electronic duo The Deer Tracks headline tonight's show, but we also like Ice Choir -- aka Pains drummer Kurt Feldman's band that owes most of its sound to Scritti Politti.
Rock Lottery @ Knitting Factory
Members of Quicksand, Afghan Whigs, DIIV, A Place to Bury Strangers, Dresden Dolls, Antibalas, Sannhet and more will be formed into new bands this morning where they'll then spend the day writing original material to perform tonight. All proceeds are for charity and is always a lot of fun.
Machinedrum (Vapor City Live), Om Unit, Nick Hook, Body Language (DJ set), Angelica Bess @ Music Hall of Williamsburg
Machinedrum is one half of Sepalcure, and also an excellent artist on his own. Tonight he celebrates his new Vapor City album with a very solid list of openers joining him.
Las Rosas, Grand Resort, Slowdance @ Radio Bushwick
Here's a good trio of bands, and a good reason to check out this new Bushwick music venue.
Revenge, Mausoleum, Engorge, Mutilation Rites @ Saint Vitus
Canadian war metal band Revenge descends upon NYC for a two-night stand at Saint Vitus this weekend. Local black metal band Mutilation Rites kick things off, and they're great too.
Moistboyz (feat. Dickie & Mickie Moist/Dean Ween), Gibby Haynes (DJ) @ Stage 48
Ween is done, but Dean Ween is continuing to provide weirdo rock with his band Moistboyz. And speaking of weirdo rock, Gibby Haynes of the Butthole Surfers is DJing, and something tells me if anyone is sure to turn a DJ set into something much more memorable, it's Gibby Haynes.
Spacehog, Sponge, Lionize, Trapper Schoepp & The Shades @ Marlin Room at Webster Hall
Glam rockers Spacehog and grunge rockers Sponge on the same bill -- is this 1997?
Lupe Fiasco @ The Wellmont Theatre
Lupe Fiasco plans to release his new album Tetsuo and Youth in early 2014 (so, in non-rap speak, basically whenever), but until then he'll be doing some shows, including four nights in the NYC-area this month. This is the first.
Anna von Hausswolff, Noveller @ The Mercury Lounge
Master of the church organ, AvH will bring her cathedral vibes -- and otherworldly voice -- to Mercury Lounge, her second NYC show this weekend with Noveller.
Goblin, Zombi @ Starland Ballroom
Italian prog legends Goblin finally went on their first North American tour earlier this year, but they've got more dates before the year ends, including tonight's NJ show and tomorrow's NYC show, both of which are with experimental duo Zombi.
Champagne Jerry w/ Ad-Rock @ Joe's Pub
Rapper/performance artist Champagne Jerry has ties to other Joe's Pub regulars like Bridget Everett and Carmine Covelli, and he'll playing one show a month there during the rollout process of his upcoming album. Tonight's show is also special because Beastie Boy Ad-Rock, who appears on CJ's recent single, will be in the house.
Pink Floyd Laser Spectacular @ The Capitol Theatre
Via LaserSpectular.com: "After 25 years of touring,Paramount's LaserSpectacular has become a cult classic, presenting the music of Pink Floyd, as you have never seen it before. Surrounded by 50,000 watts of concert quality sound, Pink Floyd's musical legacy continues as the band's concept music captures the imagination and carries listeners away on a mind-expanding journey driven by cutting-edge effects. Colorful lasers and lighting effects parallel the sonic journey as the senses are confronted with an array of glowing visual displays choreographed to the soundtrack during the 2-hour-and-20-minute show."
Deidre & The Dark @ The Gutter
Diedra just played MHOW last night with her band Savoir Adore, and tonight her solo project plays the back room at The Gutter.
For all of tonight's shows, and tomorrow's, check out our full NYC show calendar.
For laughs, check out the NYC Comedy calendar too.
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Fun Fun Fun Fest 2013 in pics: Slayer, Deerhunter, Quicksand, Judge, MIA, Cut Copy, Television, Killer Mike & MANY more
photos by Tim Griffin
Slayer/Glass Candy/Polyphonic Spree/Slayer surfer @ FFF Fest 2013
More pics from Day 1 HERE and HERE, pics from Day 2 pics HERE and HERE; and pics from Day 3 are HERE and HERE, Slayer included....
Closing Fun Fun Fun Fest, Slayer treated Austin to greatest hits and then some: "Raining Blood," "South of Heaven," "Dead Skin Mask," "Seasons in the Abyss," etc. They also dug out the aforementioned "Die by the Sword," a high point off their 1983 debut LP, Show No Mercy.The eighth Fun Fun Fun Fest happened last weekend (11/8 - 11/10) at Austin's Auditorium Shores, hosting three days of music and fun (fun fun), with such acts as MIA, Deerhunter, Slayer, Television, Thee Oh Sees, Kurt Vile, Cut Copy. Johnny Marr, The Walkmen, Jurassic 5, Killer Mike and loads more. Many of them played again as part of the FFF Nites shows, including shows presented by BrooklynVegan and Invisible Oranges.
After fooling no one with a false ending of "South of Heaven," the third backdrop of the night unfurled at the back of the stage: a parody of the Heineken logo reading "Hanneman" and bearing his life dates. The top read "Angel of Death." Reign in Blood's terrifying opening track - and closing number on Auditorium Shores - now serves as an epitaph for Slayer's fallen co-founder. - [Austin Chronicle]
We were there in the thick of it and, as mentioned above, you can check out pics from Day 1 HERE and HERE, pics from Day 2 pics HERE and HERE; and pics from Day 3 are HERE and HERE. See you again in 2014 Austin.
photos by Chris La Putt
"This show big freedia .... What the fuhhh" - Tanjeet
"Wait why do all the kids know how to twerk Lmao #bigfreedia" - LOW.KEY
"Wtf is this Big Freedia show...blank stares" - Venisha Patterson
"I still cant belive big freedia a girl . She smokeing on sum ." - shamar
"Who tf is Big Freedia??" - Mr. Ohio State
Now a record holder and more famous than ever thanks to a show on Fuse, Big Freedia returned to Brooklyn Bowl this weekend for shows on both Friday AND Saturday night and they called it "Freedia Fest". Spank Rock, who headlined the opening night of Brooklyn Night Bazaar earlier in the night, joined the Queen Diva on Friday. Saturday's ass shaking party is pictured in this post. More twerking below...
Continue reading "TV star Big Freedia touring, brought 'Freedia Fest' to Brooklyn Bowl (pics & dates)"
photos by Wei Shi
Big Freedia & her twerkers in Herald Square - 9/25/13
Yesterday (9/25), bounce queen Big Freedia set out to break the world twerking record for most people twerking simultaneously, and as you may have heard, she broke it. The whole thing went down in the early afternoon at NYC's Herald Square, where Freedia was joined by hundreds of people who came to help her succeed. According to Guinness officials, she had 358 people twerking at the same time for two minutes straight (she needed 250 to break the record). Pictures of the azz everywhere are in this post.
Big Freedia also has a reality series premiering 10/2 on FUSE (who put on this event) and a new EP, both titled Queen of Bounce, on the way. More pictures from Herald Square below...
Continue reading "pics from Big Freedia's record-breaking twerk sesh in NYC"
Fredia onstage / twerkin' granny (photos via @nonformat & @weineversleeps)
As you may have heard, today in Herald Square, Fuse helped Big Freedia set out to break the World Record for Most People Simultaneously Twerking and needed at least 250 participants to do so. She broke the record with Guinness officials on hand counting 358 people shaking their booty for two minutes straight -- including at least one septuagenarian.
We'll have more pictures from the record-breaking/shaking event soon (UPDATE: Here they are), but there are a few videos via instagram, plus the rules for breaking the record, below.
Continue reading "Big Freedia broke the World Record for twerking today in NYC"
Big Freedia at Afro-Punk Fest 2013 (more by Chris La Putt)
Bounce queen Big Freedia will bring her tour to NYC for shows on November 1 and 2 at Brooklyn Bowl (tickets), but as discussed, she'll also be in NYC today (9/25) for a very different reason. Freedia attempts to break the world twerking record for most people twerking simultaneously at Herald Square (34th St @ 6th Ave) from 11:30 AM to 1 PM. If you want to be part of it it's not too late. More info here.
Big Freedia also has a reality series and a new EP on the way. Stream a track from that EP below...
Continue reading "Big Freedia attempts to break the world twerking record in NYC today (you can still be part of it)"