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Flu Vaccinations
Attend a free Flu Vaccination Clinic. The South Dakota State Employee Benefits Program will again offer free seasonal flu vaccinations at designated state sponsored locations. The Centers for Disease Control recommends that everyone 6 months of age and older can benefit from annual influenza vaccination.
Flu Vaccinations are offered to the following groups covered by the health plan:
- State employees
- Covered spouses
- Covered dependent children (of any age)
- Retirees/COBRA members under age 65
Bring your State Health Insurance ID card with you.
Important Information
- Flu Vaccination Consent Form
- If you are an employee required to get a flu vaccination, your two part form will be available at the state sponsored vaccination clinics.
- Inactivated Flu Vaccine Information Sheet
- Exemption or Refusal to Mask Form
- Gov. Dennis Daugaard has signed an executive order requiring annual flu vaccination for state employees who deliver health care services. To view the executive order, visit http://doh.sd.gov/documents/order2014-11.pdf.
- This form only applies to employees who are required to get the flu vaccination and want an exemption or are refusing to get vaccinated.
If you are unable to attend one of the scheduled Flu Vaccination Clinics call our local DOH Offices and make an appointment to receive your flu shot. A listing of our offices is available at http://doh.sd.gov/local-offices/community-health-wic/
Flu vaccinations are safe and the best way to protect yourself from flu; by getting immunized you are also protecting more vulnerable individuals such as infants and the elderly who are very susceptible to serious illness from influenza.
Influenza is a viral respiratory illness marked by the sudden onset of fever, headache, extreme tiredness, dry cough, sore throat, runny or stuffy nose, and muscle aches. It spreads when an infected person coughs, sneezes or talks, sending the highly contagious virus into the air. Learn more at http://flu.sd.gov.
Please note that anyone with an egg allergy will be referred to their medical provider. A medical clinic is better equipped to handle a serious allergic reaction to the flu vaccine.
- Complete Your Health Screening-Completing a Health Screening between August 3, 2015 and December 31, 2015, meets one of the qualifications for the lowest deductible health plan and one-time credit in FY17. To schedule your Health Screening, click here.
- FY16 Flu Vaccination Schedule-FY16 flu vaccinations are available now. To view the flu vaccination schedule, click here.
- Health Plan ID Cards-For FY16, only members who changed health plans or made changes to spouse or dependent coverage will receive new ID cards from DAKOTACARE. Members who did not make changes should use their current health plan ID card.
- Don't forget about the Latitude Employee Assistance Program (LEAP). To learn more, click here and enter company code southdakota.


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Sunday of the Second Week of Lent. The Scripture reminds us today that many of us might be great out of the starting gate in terms of our Lenten promises, but we must strive to continue and persevere, especially through challenging times. St. Malachy's Church, Broadway and 49th, Times Square, New York City. Sunday, February 17, 2008, 6:00pm Mass.

subset: commoncrawl


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Chinese Imports Hurt U.S. Solar Companies, Trade Panel Says
The U.S. International Trade Commission took the first step toward imposing added tariffs on Chinese solar imports, saying subsidies for the products harm equipment makers such as SolarWorld AG.
The trade panel voted unanimously in Washington yesterday in a preliminary ruling on the petition by Bonn-based SolarWorld calling for antidumping and countervailing duties. The commission will now proceed with a full investigation.
"It's an incremental step, but it is a major step forward," Gordon Brinser, the president of SolarWorld's U.S. unit, said in a Dec. 1 interview anticipating the vote. "The ITC is saying there's harm or a threat of injury."
The Chinese government uses cash grants, raw-materials discounts, preferential loans, tax incentives and currency manipulation to boost exports of solar cells, according to SolarWorld's Oct. 19 complaint to the trade commission and the U.S. Commerce Department. SolarWorld, a maker of solar modules, is seeking duties to offset the practices.
The ITC is examining possible economic harm to SolarWorld from Chinese imports, while the department determines the penalty for Chinese companies that illegally dump products. The department may decide on preliminary remedies as early as January 12.
Tariffs may raise the cost of modules by 10 percent, Aaron Chew, a senior analyst at New York-based Maxim Group LLC, said in a research note yesterday.
Module Costs
SolarWorld and six other companies that haven't been publicly identified, have requested tariffs of 100 percent, saying Chinese solar manufacturers benefit from unfair government support.
The U.S. group asked the federal government to slap duties on more than $1 billion of Chinese imports.
Democratic lawmakers wrote a letter yesterday to President Barack Obama urging an investigation into the Chinese imports, which they say don't fairly compete with domestic products.
Imports of Chinese solar products have more than quadrupled from 2008 to 2010, lawmakers said in the letter. Chinese imports control half the market, benefiting from government-provided loans, cheap land, tax breaks and an undervalued currency, the lawmakers, including Senator Ron Wyden, an Oregon Democrat, and Representative Edward Markey, a Massachusetts Democrat, said.
Renewable Energy
Representatives of Chinese companies told the commission Nov. 8 that tariffs sought by U.S. competitors would make it more difficult to expand the use of renewable energy. China and the U.S. are among nations encouraging use of alternative energy sources, driving costs down across the board, so it would be unfair to penalize China, they told the panel.
China responded to the initial probe by saying it would begin its own investigation into American state support for renewable energy. China's Ministry of Commerce will consider the stimulus programs of the states of Washington, Massachusetts, Ohio and California, and two others in New Jersey, it said Nov. 25.
SolarWorld said Sept. 2 that it was cutting almost 200 jobs at its facility in Camarillo, California. Solyndra LLC, a California maker of solar panels that received $535 million in U.S. loan guarantees, blamed cheap Chinese imports for its collapse. Solyndra filed for bankruptcy on Sept. 6.
"There's a serious concern going forward with the current situation," Brinser said. "SolarWorld is a strong company, but others in the industry are struggling."
Rapid Growth
Attorneys for Suntech Power Holdings Co. Ltd. and Trina Solar Ltd., two of the biggest China-based makers of crystalline silicon panels, told the trade commission Nov. 8 that added tariffs would increase the cost of solar panels, which would then be passed on to the consumer.
Chinese solar manufacturers have said they may shift manufacturing to other countries to avoid tariffs if they're imposed.
Executives at four of China's biggest solar-panel makers have said they don't receive special treatment from the Chinese government and that they pay higher interest rates for loans than U.S. or European competitors.
SolarWorld has said that China's rapid growth in solar products is possible only with government support as it seeks to push out U.S. competitors by selling products for less than cost.
"If they continue at the rate they are going, it's not a sustainable situation," Brinser said.
Chinese Credit
China provided $30 billion in credit to its biggest solar manufacturers last year, about 20 times the amount provided by the U.S., Jonathan Silver, executive director of the Energy Department's loan program, told a congressional panel Sept. 14. Silver resigned on Oct. 6.
First Solar Inc., based in Tempe, Arizona, and SunPower Corp., based in San Jose, California, may benefit from higher sales prices stemming from the tariffs, Ahmar Zaman, an analyst at Minneapolis-based Piper Jaffray Companies Inc., wrote in a Dec. 1 research note.
First Solar isn't involved in the ITC case, spokeswoman Melanie Friedman wrote in an e-mail yesterday. SunPower is neutral, Chief Executive Officer Thomas Werner said in a Nov. 30 presentation at the Baird Clean Technology Conference.


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Safety Harbor News
Local news for Safety Harbor, FL continually updated from thousands of sources on the web.
Childhood Nostalgia Finds A New Home At Matheson History Museum
Sunday Nov 15 | WRUF-AM Gainesville | Comment?
Safety Harbor Library offers home delivery
Thursday Nov 12 | Tampa Bay Newspapers | Comment?
Weekend Platter: Talk design over drinks, sample Afro-Caribbean fare & more
Friday Nov 6 | Creative Loafing Tampa | Comment?
Hometown North Pinellas
Thursday Nov 5 | St. Petersburg Times | Comment?
Criminals targeting Safety Harbor businesses
Wednesday Nov 4 | WTSP-TV Saint Peter... | Comment?
Updated: Fri Nov 27, 2015 11:28 am
Copyright © 2015 Topix LLC


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WorldVentures is a lifestyle company that markets travel-related products. Combining the power of the internet with the time-tested strength of word-of-mouth marketing, WorldVentures is an emerging leader in the leisure travel industry.
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The Embassy Suites San Marcos is conveniently located near many top local attractions, off IH South 35 at the McCarty Exit 201. It is less than a mile
The Econo Lodge San Marcos is located approximately 30 miles from Austin-Bergstrom International and a short distance from San Marcos Premium Outlets.
The Holiday Inn Express San Marcos is located just three miles from downtown San Marcos and Texas State University. The Prime and Tanger Outlet Mall is
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Find great deals on quality San Marcos, Texas hotels & resorts, or indulge at one of our luxury resorts. Take advantage of the many amenities that can be included with your stay such as in-room internet access, wifi, room service, fitness center, pool, hot tub, steam room, and shuttle services to and from the airport. Browse our San Marcos, Texas hotels and resorts and plan your San Marcos, Texas vacation today!


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Krystle Dsouza
Krystle Dsouza
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such a lovely pic.looking so cute.


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1,424 Fans
Former insurance investigator Nate Ford, was a once-loyal employee who had recovered millions of dollars in stolen goods for his employer. But after Ford's son dies because his employer denied insurance claims, he decides to lead a team of thieves who act as modern-day Robin Hoods, providing leverage to those who need it.
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Character Bio
There seems to be little Eliot Spencer can't do when it comes to bringing down the bad guys. He can level the most muscular henchman in the blink of an eye and recognize the make and model of a gun simply by the sound it makes. He has a bevy of martial arts skills at his command, as well as extensive, first-hand experience with some of the underworld's most notorious figures. But he's not all brawn. His softer side was on display when he asked the team to help the family of an ex-girlfriend. He's also a whiz in the kitchen, able to whip up a white truffle risotto that is to die for.
Episode Screenshots
Eliot Spencer Quotes
|Season 4 / Episode 18: - The Last Dam Job
Mr. Quinn: [Hardison and Chaos are being very annoying] Can I hit him?
Eliot Spencer: Which one?
Mr. Quinn: Either one.
Eliot Spencer: [to everyone] You see? It isn't just me.
|Season 4 / Episode 14: - The Boys' Night Out Job
Alec Hardison: [regarding Nate] You know, he's worse than before he went to prison.
Shelley: He was in prison?
Eliot Spencer: Yeah, he went to jail. But he escaped.
Shelley: [to Bonanno] Shouldn't that bug you? Being a cop and all?
Detective Captain Bonanno: You get used to it.
Eliot Spencer Photos
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Browse OneOC's comprehensive listing of volunteer opportunities throughout Orange County.
'Tis the season to give & volunteer
A list of holiday volunteer & giving opportunities in Orange County.
Use our tools, resources and sample documents to take your nonprofit organization to the next level.
OneOC workshops are very thought-provoking, engaging and very productive.
This was a very valuable training that highlights the roles of volunteers, their legal rights, and the organization's liabilities.
I've attended several trainings [at OneOC] and they always are interesting and easy to understand. I always learn something new.
Anything you want to know, you will find out in this training. Instructors are very knowledgeable, clear and want to help.
From the very beginning of my dream to start Grandma's House of Hope, I have looked to OneOC for guidance and support. Every step of the way, OneOC has provided expert trainings for leadership, board engagement, strategic planning, grantwriting and more.
Copyright © 2015 OneOC. All rights reserved.


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Forex - NZD/USD edges higher but gains capped
Investing.com - The New Zealand dollar edged higher against its
U.S. counterpart on Monday, but gains were capped as last week's
strong U.S. data eased concerns over the country's outlook for
NZD/USD hit 0.8318 during late Asian trade, the session high; the pair subsequently consolidated at 0.8309, adding 0.08%.
The pair was likely to find support at 0.8353, the low of May 9 and a more than one-month low and resistance at 0.8363, the high of March 22.
The greenback strengthened broadly on Friday as recent upbeat U.S. employment data fuelled optimism over an earlier-than-expected end to the Fed's USD85 billion a month asset purchase program.
Data on Thursday showed that showed that U.S. initial jobless claims fell to the lowest level since January 2008 in the week ending May 4.
Earlier this month official data showed that the U.S. economy added more jobs than forecast in April, pushing the unemployment rate to a more than four-year low of 7.5%.
In New Zealand, industry data earlier showed that the house price index rose 0.8% in April, after a 2.4% increase the previous month.
Separately, official data showed that industrial production in China rose 9.3% in April, below expectations for a 9.5% increase and following an 8.9% rise the previous month.
The weaker-than-expected data fuelled concerns that China's economic recovery was stalling. China is New Zealand's second biggest export partner.
Elsewhere, the kiwi was higher against the euro with EUR/NZD slipping 0.14%, to hit 1.5627.
Later in the day, the U.S. was to release official data on retail sales.
Investing.com - Investing.com offers an extensive set of professional tools for the Forex, Commodities, Futures and the Stock Market including real-time data streaming, a comprehensive economic calendar, as well as financial news and technical & fundamental analysis by in-house experts.
Read more News on Investing.com or Follow us on Twitter at @ Newsinvesting


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- 13Promote
Canvas Print
Show Flyer, 3/19/12 (NOi!SE and Crashed Out)by Sam Sinister
Fine art print on bright white, fine poly-cotton blend, matte canvas using latest generation Epson archival inks. Individually trimmed and hand stretched museum wrap over 1-1/2" deep wood stretcher bars. Includes wall hanging hardware.
Flyer for an Oi! show at the Charleston (Bremerton, WA), March 19th, 2012. Featuring NOi!SE, Crashed Out, City of Vain, Opposing Force, and Back Alley Trash. You can check out NOi!SE here: https://www.facebook.com/destinycitynoise?sk=app_2405167945


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Sierra Comfort Relief Portable Massage Table PackageItem # HN-SIE001
- High-quality folding adjustable-height massage table
- Beech maple hardwood frame with 2.5-inch foam padding
- Weight capacity: 500 lbs.
- Warranty: 5 years
- Assembled dimensions: 74L x 28W x 23-33H inches
Reviewed by 3 customers
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- Relaxing
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Best Uses
- Everyday
Comments about Sierra Comfort Relief Portable Massage Table Package:
The table arrived on time. It seems very sturdy. I like the side arm rests and the elastic under the table that helps hold items in place during transport. I like the case. May have to add padding but I expected that.
- Attractive Design
- Durable
- Easy To Assemble
Best Uses
- Living Room
- Outdoors
Comments about Sierra Comfort Relief Portable Massage Table Package:
Great table, light weight, sturdy and very portable.
- I Am A:
- Single Male
- Easy to use
- Strong odor needs to air
Best Uses
Comments about Sierra Comfort Relief Portable Massage Table Package:
Well pleased thus far. It's strong and easy to use. The only negative is there is a strong odor when you first open it up. Guessing its the foam in the table. Needs to air out and should be fine.
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Ben Affleck won't run for US Senate in Mass.
BOSTON (AP) — Ben Affleck is taking his name off the list of possible candidates for U.S. Sen. John Kerry's seat, which would be open if the Democratic senator from Massachusetts is confirmed as secretary of state.
Affleck says in a Monday posting on his Facebook page that while he loves the political process, he will not be running for public office.
Speculation about the Cambridge, Mass., native rose slightly when he did not completely rule out a Senate bid during an appearance on CBS' Face The Nation on Sunday.
In his Facebook posting, Affleck says he would continue working with the Eastern Congo Initiative, a nonprofit organization that helps direct humanitarian aid to the war-torn region, and for other causes.
Affleck says Kerry would make a great secretary of state.
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Fashion Offenders
Fergie, Sarah Jessica Parker, and Heidi Klum all get an F on this week's Fashion Offenders.Watch Video »
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Beyonce and Alicia Keys double date with their famous hubbies on today's Celebs Gone Social.Watch Video »
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See what the cast of "American Beauty" is up to today.Watch Video »
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Jennifer Lopez shares an adorable photo of her look-alike daughter, plus more celebritots on social media on today's Celebs Gone Social.Watch Video »
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Sofia Vergara poses in a revealing neon bikini while her "Modern Family" castmates hit the beach in Australia on Celebs Gone Social.Watch Video »


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What a lovely Sunday morning. Tell me how great was your morning? How is the coffee? Mine is wonderful.
My coffee is great and hot! Nice cloudy day here good time to play on computer inside.
A very nice quiet, sunny, "nearly Autumn" morning with a cup of green tea and sitting on my laptop while my son watches "Sid the kid" and the one Mastiff puppy snores (yes, he snores) on the couch!!! So glad that your morning is wonderful. I think I will be making some fresh homemade banana bread shortly; I will sliced you some for your coffee!!!
Just pulled them out of the freezer (yes, I freeze them and sometimes don't even peel them first) and I have the oven heating...coming up!!! No nuts though...I may try a few almond slivers on top of one for fun though!!!
I am a tea drinker,it was good, lemon and honey. I am trying to shake off a cold
It is a cool, foggy morning here... love it!! Coffee is fresh and delicious. Life is good...even though it's not perfect...it's still worth getting up in the morning! LOL Have a great day!! :)
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I like Sunday mornings the best,drinking coffee,reading the newspaper,i like all the ads that come in the Sunday paper.Iv'e always liked looking thru the ads to see if something i wanted or needed was on sale,i have always looked foreward to reading the Sunday paper.ramrod 41-45, M 1 Answer 1 Oct 21, 2012 in Parenting & Family
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Me..another beautiful Sunday morning with a cup o coffee, look out the window and contemplate the source of life...You?


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Summer 2015 (July 31, 2015)
Greetings Russell Sage Alumnae
Pictured: Doris Fischman Roth '65 snaps a photo of Bonnie Maxon '65 (left) and Gail-Ann Brehm O'Leary '65 (right), in Avery's Garden (a gift from Virginia Kurtz Stowe '65) over Reunion weekend.
Russell Sage College AlumnaeNews brings you college news and classmate updates between print issues of Connections magazine, which is published twice a year.
In this Issue of AlumnaeNews:
Alumnae Connections: Read a special message for class leaders, find information about upcoming alumnae events and get a link to photos from Reunion.
Class Notes: Read about Sarah Kate Ellis '93, honored in Family Circle magazine; Jennifer Collins, PT, Ed.D, MPA, '78, named chair of the Physical Therapy department at Adventist University of Health Sciences; and many more alumnae.
Russell Sage Spotlights: Learn about a $2 million grant that will assist students seeking a degree in a STEM or Health Sciences discipline; Biology Professor Dorothy Matthews' Fulbright-Sponsored Research in Botswana; and fall semester Arts & Lectures events, on campus and open to the public.
Alumnae Connections
Pictured: Sarah Sterling Purnell '05, Kerianne Clark Silver '05 and Jessica Wilson '05 during Reunion Weekend. See more Reunion photos.
Calling Class Leaders!
Are you a class correspondent, class agent, Reunion chair or class officer? If so, then the Class Leader Webinar is for you! To accommodate the schedules of class leaders and involve those unable to travel to Troy for Leadership Day, the Annual Fund and Alumnae Relations staff will host a series of webinars for class leaders throughout the coming year. The first is scheduled for 9/15 at 4 p.m. and 9/16 at 7 p.m. (The agenda for both meetings is the same - we hope that by offering two different times, more will be able to participate!) Please be sure we have your preferred email address, then check your in-box for a phone number and instructions.
Celebrate a Century of Russell Sage College at Reunion 2016
All classes are invited to a community celebration on Friday, 6/3, to commemorate Russell Sage College's 100th anniversary. MORE events are scheduled 6/3-6/5, specifically for classes ending in "1" and "6." Join Russell Sage College Reunion 2016 on Facebook!
MORE RSCAA Events
Summer and fall events include a reception and tour at the New Britain Museum of American Art (New Britain, CT, 8/27); tour of the Shaker Heritage Society and lunch at the The Tailored Tea (Albany, NY, 10/7); and the Southern Connecticut Fall Luncheon (Newtown, CT, 10/7). Get all the details.
Read back issues of your alumnae magazine.
Russell Sage College Alumnae on Facebook
Summer 2015 Class Notes
Jennifer Collins, PT, Ed.D, MPA has been appointed chair of the Department of Physical Therapy at Adventist University of Health Sciences in Orlando, Florida. She previously served as the chair of Physical Therapy at Nazareth College in Rochester, New York. Her areas of expertise include the psychosocial aspects of disability, professional issues, research, management, and education.
Sarah Kate Ellis was included amongFamily Circle magazine's listing of 20 most influential moms. The award-winning media and communications strategist has been CEO and president of GLAAD since 2014.
Read more class notes and write to firstname.lastname@example.com to see your news here or in Connections.
Russell Sage Spotlights
Sage Awarded $2 Million Grant
Sage has been awarded a Collegiate Science and Technology Entry Program grant from the New York State Education Department and will receive $2 million over five years. The grant will support students seeking a degree in a STEM discipline or licensed health profession, who are underrepresented in such fields or who are from economically disadvantaged backgrounds. More than 250 students are expected to benefit from each year. Find out more about CSTEP at Sage.
Dorothy Matthews Receives Fulbright
Professor of Biology Dorothy Matthews, Ph.D., received a Fulbright Scholar award to conduct research at the University of Botswana in southern Africa. She will evaluate the effectiveness of the service initiatives provided by The Centre for the Study of HIV and AIDS at the University of Botswana. "I want to use my knowledge as a microbiologist and my skills as an educational researcher to help alleviate human suffering.... I hope that the findings that come from my Fulbright project will provide professionals in Botswana with important information as they design future research-based HIV/AIDS prevention and treatment initiatives." Read more spotlight stories.
Arts & Lectures
Fall events include the Theatre Institute at Sage's performance of Wait Until Dark (10/7-10/18) and a lecture and book signing with Marianne Schnall, author of What Will It Take to Make a Woman President? Conversations about Women, Leadership and Power (11/11). Browse the complete schedule.


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During Thanksgiving weekend thousands of people shared a video of "levitating cars" in China and now the mystery of that video has been solved.
The CCTV footage, posted on Live Leak and other sites, shows a minibus approaching an intersection when some unknown force sends the back wheels into the air along with the front wheels of another vehicle.
A third vehicle on the other side of the street also appears to do a brief hop, as if hitting a forcefield.
While the levitating illusion is extremely bizarre on film, there's actually a logical explanation.


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About WATD-FM WATD is one of those seemingly impossible ideas which actually worked and has now endured for over three full decades. The idea for the station in Marshfield emerged as the result of a prospecting trip Carol Ebert Perry and Edward Perry made in December of 1972.
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Galveston chords by Glen Campbell, added: July 9th, 2009
Profile History
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Written by Jimmy Webb.
Its actually in the key of F, but is much easier and enjoyable to play in G.
G C D7 G G7 C Am7
Galveston, oh Galveston, I still hear your sea winds blowin'
D7 G C Am7
I still see her dark eyes glowin'
D7 Em C G
She was twenty-one when I left Galveston
G C D7 G G7 C Am7
Galveston, oh Galveston, I still hear your sea waves crashing
D7 G C Am7
While I watch the cannons flashing
D7 Em C G
I clean my gun and dream of Galveston
Bb C Bb C
I still see her standing by the water
Dm Bb
Standing there lookin' out to sea
Gm C7 F
And is she waiting there for me?
Am Dm Gm C D7
On the beach where we used to run
G C D7 G G7 C Am7
Galveston, oh Galveston, I am so afraid of dying
D7 G C Am7
Before I dry the tears she's crying
Em C Bm Am7
Before I watch your sea birds flying in the sun
At Galveston, at Galveston.


text:
[quote]For a long time Star Wars fans have been clamoring for Disney/Lucasfilm to re-release the original, unaltered cut of the first Star Wars trilogy, and Comicbook.com has now confirmed with two independent reliable sources that just such a plan is under way. According to our sources, Disney has plans to release the original cut of the Star Wars trilogy on Blu-ray. Our sources indicate that the project has been under way for quite some time, but it's been challenging because of some damage to the original negatives they are utilizing. The goal is to release A New Hope, Empire Strikes Back, and Return of Jedi in their complete, unaltered, original form without the redone special edition SFX. Our sources did not have an exact date as to when the original cut of the Star Wars Trilogy would be released on Blu-ray, due to the challenges Disney has encountered in pulling everything together. However, our sources indicated the goal is to have it ready and released before Star Wars Episode VII is released in theaters.[/quote][url=http://comicbook.com/blog/2014/08/16/exclusive-original-unaltered-cut-of-star-wars-trilogy-to-be-rele/]Source.[/url]
OrderedComa8/19/2014 1:41:39 AM PermalinkMeh, I'd rather have the special edition or whatever they released in 1997 on DVD...those VHS tapes my family have are wearing out and won't last forever :/ So yeah, I'd rather have re-release of the movies from 1997 on DVD than anything else >_> The victory celebration at the end of Episode VI is so much better than the original release, I really don't like Yub Nub that much as the whole victory celebration...but yeah, I'd much rather have that version of the movie...
RagnarokUnbound8/18/2014 12:57:15 PM PermalinkI'm taking this with a grain of salt. Last I heard was Fox owned the licenses to the original trilogy for the next 20 (I think) years but they owned the licenses for A New Hope indefinitely.
TGI Skuldier8/17/2014 10:10:50 PM Permalink>Friday, 4:35pm at Disney HQ >Executive board sitting around >Trying to find ways to get everyone hyped for new Star Wars films >"We could have an advert campaign." >"Guys...." >"That could work, somebody call up Doritios, they're advert whores right?" >"Guys seriously..." >"No if you're going to call them you have to call Mt. Dew as well its a package deal..." >"Guys if you would listen for one second..." >"What about a new line of action figures?" >"No really guys..." >"We could always have old George do some kind of promo." >"Guys...." >"Frederickson what the hell is it?!?" >"Unaltered Bluray"
RomanGladiator78/18/2014 4:10:00 AM Permalink>yfw Lucas hires a group of mercs dressed as stormtroopers to break into the Disney vaults and destroy the original film reels
Link8/18/2014 1:28:14 AM PermalinkMeh, I still own them on VHS. Now if we only had a working VHS player...
dahuterschuter8/17/2014 12:38:48 PM PermalinkIt'll be an attempt at editing the existing special editions to recreate the original cut because George burned the original reels while throwing action figures of Tho' Frelmuht the garbage disposal from the Mos Eisley Cantina in the air and ranting about how it's like poetry.
THE 1ST GAMER8/17/2014 2:16:37 PM PermalinkSpeaking of Star Wars, check out the new storm trooper helmet for episode 7.
HankTheYank27Edited by HankTheYank27: 8/17/2014 7:07:21 PM PermalinkDisney could now officially be labeled as the savior of Star Wars! At first I was afraid when I heard they bought rights to it, but now I'm glad! May the force be with you fellow Guardians!
Gnome Scat8/17/2014 5:26:03 PM PermalinkI'm honestly impressed, Disney is actual doing something good for Star Wars.
DjSwagNinja8/17/2014 7:35:40 PM PermalinkAre guns and lightsabers going to be replaced by walkie talkies?
Damien SmarkdowEdited by Damien Smarkdow: 8/17/2014 4:20:39 AM PermalinkCool, the Special Editions are still better and represent Lucas' actual vision for the films. I never understood why people hated on Lucas for altering [i]his[/i] films (for the better). The redone effects make the film so much more enjoyable than the old, shitty 70s effects they used to have. As for Han shooting first, who [i]really[/i] cares? It makes no difference whether he shoots first or second; besides, it's so close you can't even tell. Him shooting first, with no retaliation from Greedo whatsoever makes him look like a cold-blooded psychopath, which he obviously isn't. [spoiler]Not being serious[/spoiler] [spoiler][i]Or am I?[/i][/spoiler]
lonepaul24418/17/2014 5:22:28 PM PermalinkSo reselling games ever other year is bad but selling the same 3 movies 20 times on different formats = ok? *sigh* No wonder we have companies like apple charging full price for the same shit as the year before, because you clowns are happy to support it.
DavistephEdited by Davisteph: 8/17/2014 3:50:50 PM PermalinkFor those who don't know, here is a good run-down of the changes made to the first three films. All changes can be found [url=http://en.wikipedia.org/wiki/List_of_changes_in_Star_Wars_re-releases]here.[/url]


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Book your room at ibis Styles Perpignan Le Canet Sud
Get an overview of this hotel3-star hotel in Canet-en-Roussillon with free parking
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Simply enter your Nectar card number when prompted. Your points will be credited 30 days after you return from your trip.*Offers may apply
Situated in Canet-en-Roussillon, this hotel is 0.6 mi (1 km) from Canet Beach and within 9 mi (15 km) of St. Jacques Church and Le Castillet. Palace of the Kings of Majorca and Saint-Cyprien Golf Club are also within 9 mi (15 km).
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This smoke-free hotel features laundry facilities, a 24-hour front desk, and free newspapers. Free WiFi in public areas and free self parking are also provided. Additionally, multilingual staff, a front-desk safe, and free wired Internet in public areas are onsite.
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Ibis Styles Perpignan Le Canet Sud features multilingual staff, complimentary newspapers in the lobby, and laundry facilities. High-speed wired and wireless Internet access is complimentary. Complimentary self parking is available on site.
Ibis Styles Perpignan Le Canet Sud is a smoke-free property.
- 24-hour front desk
- Free newspapers in lobby
- Free WiFi
- Free wired high-speed Internet
- Laundry facilities
- Multilingual staff
- Safe-deposit box at front desk
- Free self parking
- Smoke-free property
Available in all rooms: Free WiFi , Free wired high-speed Internet
Available in some public areas: Free WiFi , Free wired high-speed Internet
Free self parking
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- Climate control
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Check-in time starts at noon
Check-out time is noon
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- A tax is imposed by the city: EUR 0.79 per person, per night
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This hotel has received its official star rating from the French Tourism Development Agency, ATOUT France.


text:
Schumer Undervalues Trade with China
Byline: Daniel Griswold, SPECIAL TO THE WASHINGTON TIMES
The drums of a trade war with China continue to beat in Congress even after the Chinese government announced earlier this month that it will allow the yuan to resume appreciating against the U.S. dollar.
Led by Sen. Charles E. Schumer, New York Democrat, congressional critics of China's currency policy assert that the yuan is intentionally undervalued by as much as 40 percent. They argue that the undervalued currency makes Chinese goods artificially cheap in the U.S. market, hurting U.S. manufacturers, while it stifles U.S. exports to China, fueling our big bilateral trade deficit.
There's an element of truth to all of that. China's central bank does tightly manage the value of its currency in the foreign-exchange market, as do most other less-developed nations. An undervalued currency does make a nation's exports more competitive while making imports more expensive. But the claims made by the critics are wildly overvalued in the debate and do not justify any resort to higher tariffs against Chinese goods.
Exchange rates have only limited effects on bilateral trade balances and can be swamped by more fundamental factors. We run a large bilateral deficit with China not because of an undervalued yuan, but because China specializes in making consumer goods - such as shoes, clothing, toys and household appliances - that American consumers love to buy. Because of our low national savings rate, we in turn offer attractive assets, such as Treasury bills, that the Chinese are equally eager to buy from us.
For a number of reasons unrelated to exchange rates, the growth of our trade deficit with China has actually slowed in the past year. According to the latest monthly report from the U.S. Department of Commerce, our trade deficit with China grew only 6 percent in the first four months of 2010 compared with the same period last year, from $67 billion to $71 billion. That compares with a 46 percent jump in our trade deficit with all other countries, from $78 billion to $114 billion.
China's manipulated currency has not blunted U.S. exports to China, nor unleashed a flood of imports. In the first four months of 2010, U.S. exports of goods and services to China were up 41 percent, twice the rate of growth of exports to the rest of the world excluding China. …


text:
What bands use a 7 string guitar?
This answer has been marked for improvement.
Nevermores Jeff Loomis
Dream Theaters John Petrucci
Wes Borland of Limp Bizkit used a 7 string for most of his early career with the band.
Korns Munky
Soulflys guitarist has a signature Stealth (BC Rich)
Triumphant Return
Slayers Kerry king
Rusty Cooley uses 7 string guitars
Steve Vai
Fear Factorys guitarist does
Cannibal Corpse
Kritic Kill
Muse used a 7 string for their song Citizen Erased
Dream Theaters John Petrucci
Wes Borland of Limp Bizkit used a 7 string for most of his early career with the band.
Korns Munky
Soulflys guitarist has a signature Stealth (BC Rich)
Triumphant Return
Slayers Kerry king
Rusty Cooley uses 7 string guitars
Steve Vai
Fear Factorys guitarist does
Cannibal Corpse
Kritic Kill
Muse used a 7 string for their song Citizen Erased
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How have you grown as an actress since you were originally cast as Audrey in 24? Is there anything you wish you had known when filming the original?View Full Interview
Answered Most Recently
What is the tuning for a 7 string guitar?
Standard Rock tuning for a 7 string guitar is: BEADGBE This tuning allows for very simple power chords to be played at the lower register. The Original and Standard Jazz tuni…ng for a 7 string guitar is: AEADGBE This tuning makes it easier to add walking bass lines when playing chord-melody style. (MORE)
How do you use a guitar string winder?
A string winder consists of a rectangular socket attached to a handle on a swivel. Once you attach the string properly, the socket goes over the nut that winds the string bein…g tightened. Once the socket is over the nut, the user merely rotates the handle in the direction needed to tighten the string - the winder merely acts as a method for accelerating the nut winding process, since you can turn the nut faster with the winder than you can with your fingers. Winders are only meant to take up the majority of the string slack - once it gets fairly tight, it should be taken off and the rest of the string tuning done by hand. Use your fingers to tighten the nut to concert scale tuning, and make sure you tighten the nut screw. It's always a good idea once you've tuned all the strings once to go back around again and check them once more, as tightening strings always tends to loosen others already tuned by a little bit. At a certain point they'll all be tightened to the same relative tension and you won't have to deal with any loosening as you tighten all of them. (MORE)
What guitar strings does Buckethead use?
Buckethead uses .009 D'Addario Skinny top/Regular Bottoms He also uses Ernie Balls, different gauges. Likes 10-52s.
In Maintenance
How to String an Acoustic Guitar
If you play an acoustic guitar, sooner or later you need to replace your strings. Damage in transit, playing too hard, over-tuning and plain old wear and tear are just some of… the reasons why every guitar player should learn how to string a guitar. Follow these steps to be back in the rhythm of things in no time!Unwind your tuning posts until the strings are loose. Carefully remove the strings from the tuning post holes. Pull the old strings out through the bridge pin, which is the piece on the body of your guitar that holds all the strings. It's best to do one string at a time.Get the right strings for your guitar. It is preferable to stick with your current brand and model of strings for the sake of consistency. Be aware that not all strings are created equal, and it's best to buy the brands professional musicians use.Begin stringing your guitar by threading each string up through its proper hole in the bridge pin. The largest gauge goes at the top-most hole and they get smaller as they go down. It's important to note that "up" here means the end that is top-most when you are holding your guitar.Some guitarists like to thread and connect each string one at a time, while others like to thread them through the bridge pin all at once. Your best bet is to thread them one at a time. Once you have each string in its correct place through the pin, pull it up the length of the guitar's neck, and through the hole in the corresponding tuning post. Pull to tighten, then turn the tuning key just enough to make sure each string is secured.Using no more than a few turns at a time, rotate your tuning keys until the strings are taut but not tight. When there is no slack, you're all set to begin tuning.Some musicians like to trim the excess strings, while others prefer to leave them on. A good rule of thumb is to cut off anything more than a few inches.Learning how to string a guitar is easy once you get the idea behind it. Just remember to take your time and keep your string gauges in order.Always have an extra set of strings as a backup. Then, when you inevitably break a string, you can replace it easily and get back to playing without making a trip to the store. (MORE)
In Beginner
What Is the First String on a Guitar?
If you're trying to teach yourself to play guitar, don't let the instrument-specific terminology confuse you. A chief example of this is the way the strings of the guitar are …numbered. While it's possible to think that common sense makes knowing the numbers of the guitar strings a simple task, the truth is actually a little more frustrating.The guitar strings are numbered one to six in reverse order according to vertical position. This means that when you're holding the guitar in playing position, the string that's closest to the ceiling is actually the sixth string. This is somewhat confusing, as common sense dictates that the string closest to the ceiling, and therefore closer to your eyes, would be the first string.The guitar's first string is the one that's closest to the floor. Another way to think of it is that the first string is the one that's closest to your leg when you're holding the guitar in playing position. If you're still having trouble, there are few helpful tips you can use to remember the order of the strings.One way to think of the string numbers is by associating the numbers with pitches. The highest pitched string is always the first string in standard tuning while the sixth is the lowest pitch string. String gauge is another way to keep from getting mixed up when it comes to string numbers. The first string is always the thinnest string while the sixth string is always the thickest. Strings get progressively thicker as you go from the first string to the sixth.The thinnest, highest string is always the first string in standard tuning as well as in most commonly used altered tunings. The type of guitar also has no bearing on which string is which. Regardless of if you're playing a steel string acoustic, classical acoustic or electric guitar, the highest pitched, skinniest string is always the first. On a 12-string guitar, the two highest pitched, thinnest strings are collectively considered to be the first string.When you're first learning the guitar, all you want to do is make music. It seems useless at first, but learning how the strings are numbered is vital to making sure that you become a complete, well-rounded musician.Caring for your guitar's strings is an integral part of keeping the instrument in proper working order. Never use water to clean the stings; instead, wipe the strings and fret board down with a dry cloth. This removes sweat and grime, which improves the sound quality. (MORE)
In Lessons
Guitar 101: The Names of All Guitar Strings
When learning to play the guitar, knowing the names of the guitar strings is critical. Most guitars have six strings to correspond to the notes on the scales. To find the guit…ar string names you are looking for, follow these simple steps.This method of finding the guitar string names only works if your guitar is a six-string guitar. Luckily, most guitars are. If you are unsure if your guitar is actually a six stringer or is missing some strings, simply count the pegs. For a six-string guitar, you count six pegs.Hold your guitar as if you were going to play it. Number your strings from bottom to top, from the one closest to the floor to the one closest to the ceiling. String number one is the one closest to the floor.Each string has a specific thickness or diameter. To ensure that your strings are properly placed, check the diameter of each string by feeling along the string or giving them a gentle pluck. If the strings are placed correctly, the string closest to the ground is the thinnest in diameter and the highest-pitched in sound. As you move up, each string gets thicker and sounds lower in pitch.Name your strings that you have numbered from one to six. String one, the one closest to the ground, is high E. String two corresponds to a B note. String three is a G. String four is D. String five is A. Finally, string six, closest to the ceiling, is the low E.Finding the names of the strings on a guitar is relatively simple to do. Properly place your guitar and count its strings. Make sure that your strings are in the correct order and name them from bottom to top. Once guitar string names are mastered, learning to play the guitar is a much easier task.Guitars and other stringed instruments have a long history that dates back several thousand years. The oldest guitar-like instrument still preserved came from Egypt and is believed to be from around 1500 B.C. (MORE)
In Lessons
What are the Strings on the Acoustic Guitar Called in Order?
It is important for you to learn the names of each string on the acoustic guitar, in order, before you start getting more comfortable with learning how to play the guitar. Alt…hough it may seem strange to need to memorize the names of each chord, the reason you do this is for when you become a skilled guitarist. You need to know where to find the notes on your instrument in order to read or write music.The first string on the acoustic guitar is the E string. The first string on the guitar is also the thinnest string on the guitar, which often makes it the most fragile. The E string provides you with the highest pitch tone when you strum.The A string is the second string on the guitar and is just a little bit thicker than the E string. Due to the difference in size and placement, the A string produces a sound that is a little bit lower than the E string, although not by much.The third string on the guitar is the D string. A little thicker than the A string, the D string has a sound lower than both the E string and A string because of its size and location. This string is located towards the middle of the guitar.The fourth string on the guitar is the G string. Again progressing in thickness, the G string sits below the D string but still towards the center of the guitar. Producing a deeper sound than the three strings before it, the G string moves you closer to a deeper octave.The fifth string on the guitar is the B string. The B string is the second thickest string and is deeper than that of the four above it. Although not fully another octave above the high E string, the B string gets audibly close.The low E string is the last string of a six-string guitar. The low E string provides you with the lowest pitch; it is the thickest string, and it is closest to the ceiling of the guitar. Represented as an entire octave below high E, the low E string is the same tone, just a different octave, which protrudes a different sound.A six-string acoustic guitar is one of the most popular instruments in the world. If you are interested in learning how to play the guitar, it is crucial to first understand the names and ordering of each string on the guitar. The acronym listed above displays a sentence that states, "Every Adult Dog Growls Barks Eats." If you can remember that statement, you are also able to remember the order and the names of each string on the guitar.The first guitar strings were made of animal intestines called "catgut". "Catgut" is short for cattle-gut, and no kittens were harmed in the making of your guitar. Some of the best guitar string makers in the world still use "catgut" today. (MORE)
In Beginner
Beginner's Guide to Guitar: Understanding Guitar String Order
Guitar string order on nearly all guitars follows the same set of rules. The near-universal set-up allows for relatively simple chord structure and lead guitar patterns in mos…t rock music. Learn how to string your guitar this way, and prepare yourself for occasional tweaks that you are likely to come across in sheet music.Guitar string order runs consecutively from the lowest pitch to the highest pitch. The lowest, or deepest pitch, string is closest to your head while you are holding the guitar in playing position. The highest pitch string is closest to the floor.When a guitar string is played without holding the string down, it is said to be played in open position. Guitar strings are commonly tuned to a standard order of open position notes. The open position notes on a standard guitar, from lowest pitch to highest pitch, are E, A, D, G, B and E. Most people find this set-up to be the most conducive to playing chords. It also allows for a very simple pattern when playing lead guitar in most rock music.When explaining a chord or notes, guitar players often need to refer to individual strings to be used. It is incorrect to refer to a string by its open note if you are actually pressing on the string for a different note, so each string also has a number. String six is the low open E, string five is the open A, string four is the open D and so on.When restringing your guitar, be sure you place the right strings in the right place. Thicker strings player lower notes. String six, or low open E, is the thickest string. As you work your way consecutively, each string is a little narrower. String one is the thinnest. Use the measurements on each string's wrapping if you need help figuring out which string is thinner or thicker than another.As you become a more advanced guitar player, you have the option of experimenting with how you tune your guitar. Although many top guitar players stick with the traditional stringing method, an increasingly popular alternative is to down-tune string six to a D instead of an E. The sheet music for some songs even calls for this.Playing with the order and tensions of your guitar strings produces a unique sound in every different combination. By adjusting the tensions you change the tune and scale of the instrument allowing you to create a sound that is uniquely yours. (MORE)
In Maintenance
Picking the Right Guitar Strings for You
Buying guitar strings can be quite the simple process. Of course, if you are planning on spending lots of time on your guitar, you may wish to consider all your items. Guitar …maintenance includes changing the strings regularly to avoid damage. The more diligent you are about the care of your guitar, the longer it will last. You will find the sound of your guitar improves significantly when the strings are in good shape.Electric and acoustic guitars use different types of strings. You want to know what type of strings are recommended for your guitar. From there you can make choices based on what you want the guitar to sound like and what strings you prefer the feel of.It is tempting to run guitar strings into the ground, but it can be bad for you and bad for the guitar. It is better to keep track of your strings and notice when one is getting worn or weak. When a string breaks, it can do so with such force to cause damage to the guitar itself. That is a much more expensive repair than just replacing the strings in advance.If you are hard on your strings, it is tempting to get a larger gauge string. They can withstand a beating much better. Make sure you guitar can handle the string as well. The extra torque on the frame can damage the guitar. Know what the factory recommends before you increase the gauge too much.Coated strings are much more pricey than uncoated. They tend to be easier on the fingers and last longer as well. It is a bit of a give and take. Some guitar players dislike the feel of the coated strings. It is up to you to decide what feels best for your style of play.Hanging out in a guitar store and trying different strings is the best way to hear the sound difference. There are also places you can go online to hear the strings and how they hold sound. Depending on your style of play and your ear, one type might be better than another. The depth of the note is often the biggest difference. Taking the time to listen to all types can result in a more full musical output for you.Once you have determined your favorite string, buy in bulk. This will save you money and you know you will use the strings. It is easy to store guitar strings, and they don't go bad as long as you keep them dry and away from extreme heat change. You will always have backups when you buy this way.As round tends to be the default shape for most strings, many people have never used flat strings. Once you have tried them, you might find they work better for your style of play. Before you commit to one specific type string, try them both. The flat strings can be easier to pluck and are better for certain finger types. It is a matter of preference.Buying guitar strings is mostly a matter of personal preference. Once you have discovered what you like best there are a number of ways to save money when you purchase the strings. For the average guitar player, it is fairly easy to just stick with the comfort strings you are used to. You might find you have more talent than you know by experimenting with different styles and types of strings. The sound is different as well as the action. There is always more to learn when it comes to the guitar.It is estimated there are 20 million guitar players in the United States. Roughly 13 percent of adults in the US can play the guitar at least a little bit. (MORE)
In Guitars
Which guitar uses nylon strings?
Classical guitars commonly use nylon strings, although sometimes other synthetic materials are used. Normal acoustic guitars are built to handle the higher tension of steel st…rings, and using nylon strings can cause the neck to bend or warp over time. (MORE)
Does it matter what guitar strings you use?
yeah more than people would think. I'll break it down into laymen terms. ok strings are like shoe sizes, size 8 or 9 is very small and size 13 is very big, they all look sim…ilar but the 8 is faster than the 13 to play. so what does size have to do with it? the bigger the string the louder it is as it vibrates more, the thicker the string the better it is for low tuning which is why basses have such think strings.. along those lines. Also very thin strings can go into way higher tunings without breaking. keep in mind the heavier the set is the stiffer it is for say standard tuning, I play 13-70 on one guitar for very low tunings , it can go into standard but its very hard to bend strings and stuff, 10-46 for soloing and rhythm parts. brand and types, theres jazz type, average strings, ones made of steel, even ones with dynamite in them (Awesome if you're into metal). You don't really notice it at first but string brand and type go a long way. Some last longer and some sound better for a cheaper price. interesting fact if you break a string and you have a friend who plays a heavier gauge (size) of strings you can still use theirs. a size 0.013 string (high E) from a black metal set will go perfect on your guitar perfectly for a B. (MORE)
What guitar strings does slash use?
ernie ball power slinky an 11-49 set, their in a purple pack their impossible to miss. any 11-49 or 11-50 set will do the trick though as there's more to his sound than a ma…gical set of strings. (MORE)


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|Sq ft
|4 beds
|2.5 Ba
Fantastic Mid-Century Fixer Opportunity, Amazing Price! Enter this lovely home through the large living room with high ceilings featuring an exposed wood beam and tons of architectural windows. Retro-styled solid wood paneling that's coming back into modern fashion! With a flowing floorplan and great light, this home has tons of opportunity to add quick owner's equity. Spacious kitchen with ample counterspace, breakfast bar, and tons of cabinetry. four generous bedrooms and three quality bathrooms - some with original vintage fixtures. Master bedroom includes a private attached bath! All appliances, including washer & dryer, are included. Huge finished basement featuring a huge family room with vintage shag carpets and full-size bar. Private study and dedicated laundry room. Serene large lot in secluded, quiet location. Beautiful landscaping with numerous mature trees and planting areas as well as covered deck. Two-car garage with plenty of workspace and light. Charming, quiet ne ...(show more) ighborhood with established homes adjacent to affluent areas. Easy access to shopping, dining, and great schools. Don't miss this unique opportunity for a tremendous home in a wonderful neighborhood!
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I Am Not A Professional Just Beggining To Bake This Is The Cake I Made For Sisters Bd I Was Asked To Make Magnolia Decor So Here Is Wh
- Uploaded By nadushka
- 2013-01-22 16:51:24
I am not a professional, just beggining to bake. This is the cake I made for sister's BD, I was asked to make magnolia decor. So, here is white cake with strawberry filling, covered in white fundant with gumpaste flowers. I also added some pastries to go along with the cake. Thank you for looking!
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Are you Yolanda Fernández?Claim your profile
Publications (42)151.42 Total impact
Article: Abstract OT2-2-03: MERIBEL study: Efficacy of eribulin in first line of taxane-resistant patients with HER2 negative metastatic breast cancerCancer Research 05/2015; 75(9 Supplement):OT2-2-03-OT2-2-03. DOI:10.1158/1538-7445.SABCS14-OT2-2-03 · 9.33 Impact Factor
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ABSTRACT: The increase in life expectancy in the western world means that we are faced with patients diagnosed with breast cancer in old age with increasing frequency. The management of these cases is a challenge for the oncologist, who must take into account the conditions associated with advanced age and the lack of trials in this population. In this review, we addressed the incorporation of geriatric assessment methods that may be useful in making decisions, the particular biological characteristics of breast cancer in elderly patients and their treatment in both localized and advanced disease. Finally, we collected recommendations based on scientific evidence regarding the monitoring and life-style after finishing treatment.Clinical and Translational Oncology 10/2013; 16(4). DOI:10.1007/s12094-013-1113-2 · 2.08 Impact Factor
Article: Mutational analysis of BRCA1 and BRCA2 in hereditary breast and ovarian cancer families from Asturias (Northern Spain)[Show abstract] [Hide abstract]
ABSTRACT: The prevalence of BRCA1 and BRCA2 mutations in Spain is heterogeneous and varies according to geographical origin of studied families. The contribution of these mutations to hereditary breast and ovarian cancer has not been previously investigated in Asturian populations (Northern Spain). In the present work, 256 unrelated high-risk probands with breast and/or ovarian cancer from families living in Asturias were analyzed for the presence of a BRCA1 or BRCA2 gene mutation from October 2007 to May 2012. The entire coding sequences and each intron/exon boundaries of BRCA1/2 genes were screened both by direct sequencing and Multiplex Ligation-dependent Probe Amplification (MLPA). A total of 59 families (23%) were found to carry a pathogenic germ line mutation, 39 in BRCA1 and 20 in BRCA2. Twenty nine additional families (12%) carried an unknown significance variant. We detected 28 distinct pathogenic mutations (16 in BRCA1 and 12 in BRCA2), of which 3 mutations in BRCA1 (c.1674delA, c.1965C>A and c.2900_2901dupCT) and 5 in BRCA2 (c.262_263delCT, c.2095C>T, c.3263dupC, c.4030_4035delinsC, c.8042_8043delCA) had not been previously described. The novel mutations c.2900_2901dupCT in BRCA1 and c.4030_4035delinsC in BRCA2 occurred in 8 and 6 families respectively and clustered in two separated small geographically isolated areas suggesting a founder effect. These 2 mutations, together with the Galician BRCA1 mutation c.211A>G (9 families), and the common BRCA1 mutation c.3331_3334delCAAG (6 families), account for approximately 50% of all affected families. By contrast, very frequent mutations in other Spanish series such as the BRCA1 Ashkenazi founder mutation c.68_69delAG, was found in only one family. In this study we report the BRCA1 and BRCA2 spectrum of mutations and their geographical distribution in Asturias, which largely differ from other areas of Spain. Our findings may help design a first step recurrent mutation panel for screening high-risk breast and/or ovarian cancer families from this specific area.BMC Cancer 05/2013; 13(1):243. DOI:10.1186/1471-2407-13-243 · 3.36 Impact Factor
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ABSTRACT: Fulvestrant is a selective estrogen receptor downregulator, behaving as a complete antagonist. It was initially approved, at a dose of 250mg, to treat hormone dependant breast cancer in second line setting. However, a series of pharmacological and pre-clinical studies have suggested that a higher dose of 500mg may be more effective. The present work summarizes and discusses clinical trials that have aimed to test the benefits of administering fulvestrant at a higher dose. The data support the use of a higher, and more possibly, effective dose of the agent.Cancer Treatment Reviews 07/2012; 39(2). DOI:10.1016/j.ctrv.2012.06.003 · 7.59 Impact Factor
Article: Pegylated Liposomal Doxorubicin and Gemcitabine in a Fixed Dose Rate Infusion for the Treatment of Patients With Poor Prognosis of Recurrent Ovarian Cancer A Phase Ib Study[Show abstract] [Hide abstract]
ABSTRACT: Pegylated liposomal doxorubicin (PLD) is currently the reference treatment for platinum-resistant ovarian cancer. The combination of PLD and gemcitabine and the administration of gemcitabine at a fixed dose rate infusion (FDRI) seem to have additive activity in this disease setting. We have launched a phase Ib study with the combination of FDRI gemcitabine followed by PLD in recurrent ovarian cancer with a platinum-free interval of less than 1 year, with parallel pharmacokinetic and pharmacogenetic studies. The starting dose of gemcitabine was 1500 mg/m², 10 mg/m² per minute, every 2 weeks (± 250 mg gemcitabine titration depending on toxicity), followed by PLD 35 mg/m² every 4 weeks. Gemcitabine pharmacokinetics and equilibrative nucleoside transporter 1, deoxycytidine kinase, and ribonucleotide reductase M1 gene expression levels were studied. Thirty-five patients were treated at 3 different dose levels (DL). Dose level 1 was not tolerated. Nonfrail patients continued to be treated at DL-1 (G 1250 mg/m² on day 1 and PLD 35 mg/m² on days 1 and 15). Of 10 evaluable nonfrail patients, 4 displayed dose-limiting toxicity. Frail patients were treated at DL-2 (G 1250 mg/m on day 1 and PLD 35 mg/m² on days 1 and 15). Of the 12 evaluable frail patients, 3 developed dose-limiting toxicity. Neutropenia, palmar-plantar erythrodysesthesia and stomatitis were the most common toxicities. The response rate was 42.8% (95% confidence interval [CI], 34.5%-51.1%), with 17.1% (6/35) complete responses and 25.7% (9/35) partial responses. The median progression-free survival was 7.7 months (95% CI, 2.2-13.1). The median overall survival was 13.9 months (95% CI, 9.4-18.4). The administration of PLD after gemcitabine did not influence gemcitabine pharmacokinetics or its metabolites. The addition of PLD to gemcitabine caused a larger and longer induction of the ribonucleotide reductase M1 gene. Patients with higher baseline levels of deoxycytidine kinase had longer progression-free survival. The recommended dose for a phase II study of patients with recurrent ovarian cancer having poor prognosis is PLD, 35 mg/m² on day 1, and gemcitabine, 1000 mg/m² on days 1 and 15 delivered at an FDRI of 10 mg/m per minute in 28-day cycles.International Journal of Gynecological Cancer 04/2011; 21(3):478-85. DOI:10.1097/IGC.0b013e31820d738c · 1.95 Impact Factor
- Clinical and Translational Oncology 08/2010; 12(8):581-581. DOI:10.1007/s12094-010-0558-9 · 2.08 Impact Factor
Article: Impact of the incorporation of tyrosine kinase inhibitor agents on the treatment of patients with a diagnosis of advanced renal cell carcinoma: Study based on experience at the Hospital Universitario Central de Asturias[Show abstract] [Hide abstract]
ABSTRACT: For nearly the past two decades, cytokines (CKs) have been the only systemic treatment option available for advanced renal cell carcinoma (RCC). In recent years, tyrosine kinase inhibitors (TKIs) have demonstrated clinical activity on this tumour. Our purpose is to describe one centre's experience with the use of CKs and TKIs in the treatment of patients with advanced RCC. This study was designed as a retrospective chart review of RCC patients who were treated with CKs and/or TKIs in our department between July 1996 and June 2008. Efficacy and toxicity were assessed using World Health Organization (WHO) criteria. The Kaplan-Meier method was used to estimate progression-free (PFS) and overall (OS) survival. Ninety-four patients were classified into three groups depending on the modality of treatment administered: 46 were treated with CKs alone and/or chemotherapy (27 with immunotherapy, one with chemotherapy and 18 with both), 28 with TKIs alone (25 with sunitinib and 13 with sorafenib) and 20 with TKIs in second-line treatment following failure with CKs (17 with sunitinib, eight with sorafenib, four with bevacizumab and one with lapatinib). The median age was 60 years in the CK group and 65 and 62, respectively, in TKI in first and second-line treatment groups. Eighty-five percent of patients treated with CKs and 75% in the TKI group in first-line treatment and 80% in second-line treatment were men. Overall, 89% of patients had favourable risk, and 11% had intermediate risk. All patients were considered evaluable for toxicity. The main grade 3-4 (%) toxicity was asthenia for both groups, (ten in TKIs and 15 in CKs). Other grade 1-2 toxicities were mucositis (39), bleeding (8), hypertension (19), skin toxicity (33) and hypothyroidism (12.5) associated with TKIs; and anaemia (33), cough (29), asthenia (39) and emesis (14) associated with CKs. The objective response rate among 80 patients evaluable for activity was 10.6% with CKs and 46.5% and 35%, respectively, with TKIs in first- and second-line treatments. Disease stabilisation with CKs was recorded at 59% of patients and with TKIs 25% and 50% in first- and second-line treatment groups, respectively. The median progression-free survival (PFS) with CKs was 122 days [95% confidence interval (CI) 82-162] and with TKIs 201 days (65-337) in the first and 346 days (256-436) in second-line treatment groups. The median overall survival (OS) was 229 days (142-316) and 2,074 days (1,152-2,996) for patients treated with CKs and TKIs. Our results are in line with the activity and survival rates previously reported in the literature regarding the use of TKIs for patients with advanced RCC in first- and second-line treatment, which has demonstrated an acceptable toxicity level.Clinical and Translational Oncology 08/2010; 12(8):562-7. DOI:10.1007/s12094-010-0554-0 · 2.08 Impact Factor
Article: Gonzalez EE, Villanueva N, Fra J, Berros JP, Jimenez P, Luque M et al.. Activity of topotecan given intravenously for 5 days every three weeks in patients with advanced non-small cell lung cancer pretreated with platinum and taxanes: a phase II study. Invest New Drugs 29: 1459-1464[Show abstract] [Hide abstract]
ABSTRACT: Topotecan, a semi-synthetic camptothecin analogue with topoisomerase I interaction, has shown to be an active agent in the treatment of advanced refractory lung cancer. This paper describes the authors' experience with this drug when used as a single agent in patients (pts) with advanced non-small cell lung cancer (NSCLC) refractory to platinum- and taxane-containing chemotherapy regimens. Thirty-five patients with NSCLC refractory to previous chemotherapy and KI ≥ 60% were included in the study. Their characteristics are as follows: median age of 52 years (range 43-69) and Karnofsky PS of 70 (60-80); 27 were male and 8 were female. Twenty-one (60%) patients had adenocarcinoma; eleven (31.4%), squamous cell, and three (8.5%), undifferentiated carcinoma. There was a median of two disease sites and two prior chemotherapy regimens. Topotecan was administered at a dose of 1.25 mg/m(2) I.V. daily for 5 days, repeated every 21 days until disease progression, maximal response, or intolerable toxicity. After 73 cycles, patients received a median of 2 treatment cycles (1-9). All patients except one were considered evaluable for toxicity; eight episodes (24%) of nausea/vomiting and two episodes (6%) of grade 1-2 asthenia, respectively, were reported. Four (12%) patients developed grade 1-2 anemia and two (6%) subjects suffered grade 3 anemia. Seven (21%) patients had grade 1-2 neutropenia and one (3%) presented grade 5 neutropenia. In 33 patients evaluable for activity of the 35 subjects included in the study; one (2.8%) presented a partial response; nine (25.7%) had stable disease, and 23 (65.7%) exhibited disease progression. Median time to progression and overall survival were 54 (12-210) and 70 (12-324) days, respectively. Intravenous topotecan at that dose and administration schedule displays scant activity in terms of response rate in individuals with advanced NSCLC previously treated with platinum and taxanes. The role and usefulness of chemotherapy in this setting warrants further investigation and confirmation through comparative studies.Investigational New Drugs 05/2010; 29(6):1459-64. DOI:10.1007/s10637-010-9442-2 · 2.92 Impact Factor
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ABSTRACT: The following manuscript summarises the content of the Breast Symposium that was held in May 2008 in Barcelona in which four controversies regarding the management of breast cancer were discussed. The design of the symposium included two speakers per controversy, one in favour and one diverging, and the audience had to vote before and after the presentations to assess changes in the participants' views. The four controversies included: (1) the role of non-conventional predictive factors in selecting treatment for breast cancer; (2) the role of surgery in disseminated disease; (3) are taxanes indicated in the adjuvant treatment of patients with lymph-node-negative disease?; (4) is treatment with tamoxifen (TAM) always required after surgery in patients with ductal carcinoma in situ (DCIS)? The symposium concluded with the presentation titled: 'Features of a well designed clinical trial in the adjuvant treatment of breast cancer'.Clinical and Translational Oncology 04/2010; 12(4):278-86. · 2.08 Impact Factor
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ABSTRACT: The following manuscript summarises the content of the Breast Symposium that was held in May 2008 in Barcelona in which four controversies regarding the management of breast cancer were discussed. The design of the symposium included two speakers per controversy, one in favour and one diverging, and the audience had to vote before and after the presentations to assess changes in the participants' views. The four controversies included: (1) the role of non-conventional predictive factors in selecting treatment for breast cancer; (2) the role of surgery in disseminated disease; (3) are taxanes indicated in the adjuvant treatment of patients with lymph-node-negative disease?; (4) is treatment with tamoxifen (TAM) always required after surgery in patients with ductal carcinoma in situ (DCIS)? The symposium concluded with the presentation titled: 'Features of a well designed clinical trial in the adjuvant treatment of breast cancer'. KeywordsBreast cancer-Non-conventional predictive factors-Surgery-Taxanes-Adjuvant treatment-Negative lymph node-Tamoxifen-DCIS-Clinical trial designClinical and Translational Oncology 04/2010; 12(4):278-286. DOI:10.1007/s12094-010-0504-x · 2.08 Impact Factor
Article: 42 Magnetic resonance imaging (MRI) evaluation of pathologically residual tumors in breast cancer after neoadjuvant chemotherapy: experience of 2 centres in SpainEJC Supplements 03/2010; 8(3):70-71. DOI:10.1016/S1359-6349(10)70073-2 · 9.39 Impact Factor
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ABSTRACT: Breast cancer treatment currently requires the joint efforts of a multidisciplinary team to effectively combine chemotherapy, hormone therapy, biological agents, surgery and radiation therapy when needed. To develop such a treatment plan, it is important to know the benefits as well as the potential toxic effects of each therapy. Thus, many patients with early breast cancer complain of collateral adverse events such as fatigue, nausea, vomiting, loss of libido, hot flashes, night sweats or neuropathy due to the complex therapies they are receiving. To date, the treatment of such symptoms is an important issue that greatly affects the quality of life of these patients. In this review, we report the content of a multi-expert meeting where the incidence of and medical approach to some of the most common adverse events encountered during the treatment of patients with early breast cancer were analysed.Clinical and Translational Oncology 01/2010; 12(1):32-42. DOI:10.1007/s12094-010-0464-1 · 2.08 Impact Factor
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ABSTRACT: Metastatic breast cancer is ultimately an incurable disease, although recent data have shown that its incidence is decreasing and that patients with metastatic breast cancer live longer. This improvement in survival seems to be linked with the introduction of new therapeutic agents, novel combinations of existing therapies and targeted therapies. Our increasing understanding of the molecular biology of metastatic disease has allowed the development of therapies aimed at specific molecular targets. Some of these have already been approved for the treatment of metastatic breast cancer in combination with cytotoxics, and others have shown promising results regarding disease-free survival, overall response rates and time to disease progression. Given the enormous amount of information about drug discovery in cancer, it is important to be familiar with the present state of the treatment of metastatic breast cancer. The purpose of this review is to provide an update on the development of some of the most promising novel agents and treatment strategies in metastatic breast cancer.Cancer Treatment Reviews 10/2009; 36(1):33-42. DOI:10.1016/j.ctrv.2009.10.001 · 7.59 Impact Factor
Article: Evaluation of international treatment guidelines and prognostic tests for the treatment of early breast cancer[Show abstract] [Hide abstract]
ABSTRACT: The clinical decision to treat early-stage breast cancer with adjuvant chemotherapy is sometimes a difficult one because 70-80% of patients who receive chemotherapy would probably have survived without it. To help clinicians in this decision-making process, different tools or 'decision aids' have been developed for the treatment of early breast cancer over the years. Some of these tools include clinical treatment guidelines and computer-based programs as well as different prognostic and/or predictive tests such as those based on gene expression profiles or the presence minimum invasive disease. All of these tools try to individualize as much as possible the estimation of the risk of breast cancer relapse and death and to facilitate the clinical decision about giving additional treatment, and ultimately the most appropriate treatment to be given. Thus, it is important for clinicians to be aware of not only the existence of these tools or 'decision aids', but also to know how they have been developed, how frequently there are revised and if they have been validated. In order to address all these concerns, we have carried out a critical review of the most important prognostic tests and clinical guidelines for the treatment of early breast cancer. Information regarding their development process as well as frequency of revision, validations that have been performed and main limitations of each tool were gathered and critically analyzed.Cancer Treatment Reviews 11/2008; 34(8):701-9. DOI:10.1016/j.ctrv.2008.04.002 · 7.59 Impact Factor
Article: Pulmonary toxicity in patients treated with gemcitabine plus vinorelbine or docetaxel for advanced non-small cell lung cancer: Outcome data on a randomized phase II study[Show abstract] [Hide abstract]
ABSTRACT: Studies with the gemcitabine/vinorelbine (GV) or the gemcitabine/docetaxel (GD) combinations have shown similar efficacy and less toxicity compared to platinum-based chemotherapies, in patients with advanced non-small-cell lung cancer (NSCLC). The present trial was designed to test the efficacy and safety of both, GV and GD, combinations. Chemotherapy-naïve patients (n=39)<or=75 years of age, KPS>or=60% and adequate hematological, renal and hepatic function were randomly assigned to receive G 1,000 mg/m2+either V 25 mg/m2 or D 35 mg/m2 (all of which were administered i.v.) on days 1 and 8 every 21 days. Baseline characteristics were comparable in GV (n=20) and GD (n=19) groups. Results indicated objective response of 7 (35%) vs 6 (31%) patients and median time-to-treatment failure of 120 versus 90 days in the GV and GD arms, respectively. The most common non-hematological toxicities were (GV vs GD): grade 2-4 pulmonary toxicity in 1 (5%) vs 7 (37%); grade 2-3 diarrhea 0 versus 4 (21%) and edema 1 (5%) vs 3 (16%); grade 3-4 hematological toxicities occurred in 3 (15%) vs 1 (5%) patients. Our results indicate that the combination of gemcitabine/docetaxel does not have a favorable safety profile with this schedule of administration, particularly in terms of pulmonary toxicity.Investigational New Drugs 02/2008; 26(1):67-74. DOI:10.1007/s10637-007-9073-4 · 2.92 Impact Factor
Article: Evidence-based use of taxanes in the adjuvant setting of breast cancer. A review of randomized phase III trials[Show abstract] [Hide abstract]
ABSTRACT: Six major randomized clinical trials evaluating the role of taxanes in the adjuvant setting of breast cancer have demonstrated significant improvements in terms of efficacy in favour of the taxane treatment arm. In all cases, different anthracycline-based regimens were used as the control arm. Nevertheless, many clinicians are still not sufficiently convinced to incorporate the routine use of taxanes in the adjuvant treatment of breast cancer. There are two main objections, first the possible lack of effectiveness of chemotherapy in hormone-receptor positive tumors and second, some of the anthracycline-based control arms used in these trials were not the optimal ones. In this review, we have searched and analyzed all randomized studies that evaluated the role of taxanes in the adjuvant setting of breast cancer patients and have reported results in terms of efficacy or tolerance. The suitability of the control arm, the prospective definition of patient's subgroups and the statistical methodology were taking into account. The objective of this review was to analyze if, at this point in time, there is sufficient evidence to support the routine use of taxanes in the adjuvant setting of breast cancer, and if it is valid for all subgroups including hormone-receptor and Her2/neu positive breast cancer patients. Other objectives of this review were to define the optimal regimen for administration of taxanes, how the tolerability of taxanes may be improved and also, to investigate any potential differences in efficacy or tolerability between docetaxel and paclitaxel.Cancer Treatment Reviews 09/2007; 33(5):474-83. DOI:10.1016/j.ctrv.2007.04.006 · 7.59 Impact Factor
Article: Activity of intravenous Topotecan in patients with advanced non-small cell lung cancer pre-treatred with platinum and taxanes: Results of the first analysis: P2-318Journal of Thoracic Oncology 08/2007; 2(Supplement 4). DOI:10.1097/01.JTO.0000284026.13148.b8 · 5.28 Impact Factor
Article: Pulmonary toxicity in patients treated with a combination of gemcitabine (G) associated to docetaxel (D) or vinorelbine (V) for advanced non-small cell lung cancer (NSCLC): outcome data on a randomized phase II study: P2-254Journal of Thoracic Oncology 08/2007; 2(Supplement 4). DOI:10.1097/01.JTO.0000283962.44333.2c · 5.28 Impact Factor
Article: Cisplatin plus gemcitabine with or without vinorelbine as induction chemotherapy prior to radical locoregional treatment for patients with stage III non-small-cell lung cancer (NSCLC): Results of a prospective randomized study[Show abstract] [Hide abstract]
ABSTRACT: To evaluate possible improvement in objective response of adding vinorelbine (V) to the combination of cisplatin/gemcitabine (CG) in induction chemotherapy for stage III NSCLC, patients (n=154) aged < or =75 years, Karnofsky index > or =70%, were stratified by stage (IIIA versus IIIB) and randomly assigned to receive: C (50mg/m(2) i.v.) plus G (1250mg/m(2) i.v.) or CG plus V (25mg/m(2) i.v.). All drugs were administered on days 1 and 8 of an every 3-week cycle. At conclusion, local treatment (LT) with surgery and/or radiotherapy was scheduled. The results indicated that, following a median of 3 cycles, the overall efficacy was 65% in the CG and 61% in the CGV group. Most patients in both groups received radiotherapy as part of their LT. Pathological complete response was confirmed by surgery in 18% in the CG and 25% in the CGV group. Median progression-free survival was 368 days in the CG and 322 days in the CGV group. There were no statistically significant differences in toxicities between groups. We conclude that the CG and CGV combinations had similar efficacy and moderate toxicity, without accruing to the triplet combination.Lung Cancer 02/2007; 55(2):173-80. DOI:10.1016/j.lungcan.2006.09.021 · 3.96 Impact Factor
Article: Radioterapia torácica con 70 Gy concurrente con docetaxel o paclitaxel semanal tras quimioterapia de inducción en pacientes con carcinoma de pulmón no microcítico localmente avanzado: Estudio prospectivo de tolerancia y eficacia[Show abstract] [Hide abstract]
ABSTRACT: INTRODUCCIÓN: La quimioterapia (QT) y la radioterapia torácica (RT-T) constituyen el tratamiento estándar para los pacientes con carcinoma de pulmón no microcítico localmente avanzado inoperable/irresecable (CPNM-I) aunque el mejor esquema de administración está por determinar. MATERIAL Y MÉTODOS: Se ha realizado un estudio prospectivo en pacientes con CPNM-I estadio IIIA o IIIB no quirúrgicos, para determinar la tolerabilidad y el control local utilizando el siguiente esquema: 7 ciclos de Docetaxel (D: 20 mg/m2) o Paclitaxel (P: 60 mg/m2) semanal, concurrente con RT-T (2 Gy diariamente de lunes a viernes, dosis total 70 Gy, durante 7 semanas) después de 3 ciclos de QT de inducción basada en cisplatino (CDDP+gemcitabina +/-vinorelbina). RESULTADOS: Desde Diciembre 1999 a Diciembre 2004, cincuenta y dos pacientes de 129 tratados con QT de inducción fueron considerados elegibles para el análisis: 27 recibieron Docetaxel y 25 Paclitaxel. La mediana de semanas de tratamiento administradas fue 5 para el D (rango 7-3) y 6 para el P (7-1). 40% (D) y 58% (P) de los pacientes en cada grupo completaron 7 semanas y las dosis programadas del tratamiento. La toxicidad registrada incluye (D/P;%): Esofagitis grado (G)I (22/18); GII (25/29), GIII (30/8), neumonitis G I-II (14/5), diarrea GI-II (14/0). La progresión local y mediana de tiempo hasta la progresión local fue 41% y 180 días para D y 46% y 240 días para P. CONCLUSIONES: Los resultados de este pequeño estudio prospectivo sugieren que la asociación concurrente de radioterapia torácica con docetaxel o paclitaxel semanal ofrece un control similar de la enfermedad así como una tendencia a una menor toxicidad no hematológica con paclitaxel.12/2006; 29(10). DOI:10.4321/S0378-48352006001000005
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Hospital Central de AsturiasOviedo, Asturias, Spain


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Lincoln Writes to T. A. Cheney About the Fugitive Slave Law
"Justice and fairness to all" is Lincoln's message in this letter to New York abolitionist T. Apolian Cheney.
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text:
Twist and turn
Architects who are fascinated by non-orthogonal architectural forms regularly feel the lash of knotted cords wielded by white-faced monks of the Old Modernism. One of the big complaints from the Calvinists is that their forms are either whimsical and irrational, or self indulgent and artsy, having foundation in neither science nor logic.
So, one of the big things for the Non-Orthog has been the development of algorithms for generating 'objective' forms. No, not wacky forms but forms generated by the studied manipulation of complex mathematical equations. Which are a tad more sophisticated that that ninety degrees in all directions stuff beloved by the Old Dims.
The Non-Orthogs also point to the gradual emergence of bespoke mass production. Stir in the mathematics of such things as planar quadrilateral meshes and CADCAM and you have people such as Skylar Tibbits and Marc Fornes at the SJET blog for which I'm grateful to Marcus Fairs at that terrific blog Dezeen. As is almost always the case with this kind of site, the links are as interesting as the main stuff.
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Ginnifer Goodwin: I've Been Dieting Since I Was 9
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"Big Love"'s Ginnifer Goodwin has a big secret: she's been dieting since the age of nine!
"I have been a member of Weight Watchers for 23 years and I'm back on it right now," she reveals in the January issue of Health magazine. "It's the only thing on the planet that doesn't dehydrate you or just make you miserable."
Growing up in Memphis, Goodwin admits she wasn't always so health-conscious.
"I really did go through a period when I was very little when I remember realizing that vegetables did not come out of the ground deep-fried," she recalls. "I changed my eating habits in fourth grade because I was a heavy little girl and I was unhappy."
"I remember my mom making dinner for me the first night that I was on this new program, and I burst out crying because the vegetables were green," she tells the mag. "I thought she was trying to starve me to death."
Now that she's older, Goodwin balances her diet with ballet classes and heavy cardio sessions at her local gym.
"I have a trainer who used to be a New York City Ballet ballerina, and she does a lot of hybrid Pilates ballet," she says. "I like the elliptical, 'cause I feel like I'm dancing. And I'm also big on speed-walking outside. Like, I'll speed-walk a couple of miles, get a cup of coffee, speed-walk back. It's so easy! Just break a sweat for 30 minutes and you're fine."
Though she sometimes still struggles with her appearance, the actress -- who's currently dating actor Joey Kern -- says that she's learned to embrace her figure.
"Even when I'm too heavy, I'm still confident because I never actually let myself go," Goodwin says. "I can be indulgent for six months and put on some weight, but I still never actually get to the point of being unhappy and self-destructive."
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ok i know its not the food network but what meal tips can you all come up with based on me using a gf grill and a hob with pots and pans and a mcrowave oh yeah and a toaster.
i tend to use chicken breasts tuna steak lean beef tuna tins white fish fillets salmon pasta rice bread and loads of veggies.
an low fat high carb tasty meals you like to whip up?


text:
The Australian longitudinal study of health and relationships
1 Australian Research Centre in Sex, Health & Society, La Trobe University, 215 Franklin St, Victoria 3000, Australia
2 National Centre in HIV Social Research, University of New South Wales, Sydney, New South Wales 2052, Australia
BMC Public Health 2007, 7:139 doi:10.1186/1471-2458-7-139Published: 4 July 2007
Ensuring the sexual and reproductive health of the population is essential for the wellbeing of a nation. At least three aspects of sexual and reproductive health are among the key policy issues for present Australian governments: maintaining and increasing the birth rate; reducing the abortion rate; and preventing and controlling Chlamydia infections.
The overall aim of the Australian Longitudinal Study of Health and Relationships is to document the natural history of the sexual and reproductive health of the Australian adult population.
A nationally representative sample of Australian adults 16–64 years of age was selected in a two-phase process in 2004–2005. Eligible households were identified through random digit dialling. We used separate sampling frames for men and women; where there was more than one eligible person in a household the participant was selected randomly. Participants completed a computer-assisted telephone interview that typically took approximately 25 minutes to complete. The response rate was 56%. A total of 8,656 people were interviewed, of whom 95% (8243) agreed to be contacted again 12 months later. Of those, approximately 82% have been re-contacted and re-interviewed in 2006–07 (Wave Two), with 99% of those agreeing to be contacted again for Wave Three.
ALSHR represents a significant advance for research on the linked topics of sexual and reproductive health. Its strengths include the large sample size, the inclusion of men as well as women, and the wide age range of the participants.


text:
Looking for John (Jock) O'GRADY New Zealand
Journal by Patog
Any Marriage details on John (Jock) O'Grady b 1893 NZ, son of John Joseph O'Grady b 1864 Milton NZ d 1945 Picton nz, and Margaret Teresa McGrath b 1869 Ohio d 1945 Picton nz. I have tried Births, Deaths and Marriages but there are several possibilities. Any help or suggestions appreciated.
Surnames: NONE
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