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Loons Fantasy Camp
Dow Diamond- Midland, MI: Last week I was lucky enough to participate in a Fantasy Camp hosted by the Great Lakes Loons. This was rescheduled after we were rained out last month. Unfortunately, that meant that the Loons players and coaches were away in Lansing while we were there. They still took great care of us, though. Walking into the locker room and seeing my name above the locker was awesome, just like I dreamed about when I was ten years old. We started out as usual by playing catch to warm up, then they took us to the indoor batting cages to get some swings in. I even snuck Brian down to take a few cuts.
We were split up into Blue and White teams wearing Miller Lite shirts, with my White team being the visitors. We took some infield and outfield practice, and I got stuck in the latter where I have no business playing. As the visitors, we were up to bat first. I held my own at the plate, going 1-3 and getting on base all three at-bats. My hit was a solid liner up the middle, so I was happy with that one. It was also a thrill to hear my name announced and be on the video board.
While I was mostly stuck in the outfield, but did get to play shortstop for an inning. I caught the only ball hit to me, a pop fly over second. I was a little disappointed that I didn't get to actually play second, since that's my position, but still had fun in the field.
Up in the stands, Lou E Loon took the camera from Trevor to take a few selfies. He's definitely one of the best mascots around.
As for the rest of the game, the Blue team just killed us. They simply made the plays in the field and got some hits to drop in. Final: Blue 10, White 1.
After the game, the Loons gave away some prizes and Lou E signed autographs for the kids. In all, this was a great experience and I'm grateful for the opportunity. Thank you to the Loons and Miller Lite for sponsoring this.
UPDATED: This was sent to me by the Loons this morning. Our group shot with both teams.
All other photos property of Minoring In Baseball
Going 'Nuts in Lansing
Lansing Lugnuts vs Bowling Green Hot Rods (Midwest League)
Cooley Law School Stadium-Lansing, MI: After Brian finished his seminar, we got a bite to eat at the Nuthouse, then went back to see the Lugnuts host the Hot Rods.
One cool new aspect of Cooley Law School Stadium is the Michigan Baseball Hall Of Fame. Some of the best players who are from Michigan or played in the state are honored. Some of my childhood favorites like Alan Trammell and Jim Abbott are honored, as well as some classic Tigers like Al Kaline, Charlie Gehringer, and broadcaster Earnie Harwell.
The game was a fun one for us to watch, and a good one for the home team. This game was special also, as it was the first one all three kids attended. I'm glad Lily finally made it to a game with us this season. Trevor took a good pic with his phone of himself, my dad, and I. I also took one using the MiLB In The Park app. Apparently, Trevor's phone does a little better job.
As for the game action, the Lugnuts scored in the early, middle, and late innings. Midwest League Player of the Year Ryan McBroom had a big night offensively. He went 2-3 with a booming home run, a double, and plates five RBI's. Center fielder D.J. Davis also contributed two RBI's on the night, going 2-4. Alex Maldonado and Christian Vazquez each had a pair of hits, also.
On the hill for the 'Nuts, spot starter Tim Mayza threw five shut-out innings, giving up one hit and striking out five. In relief, Dusty Isaacs gave up one run, and Phil Kish two before shutting the door.
In the late innings, I strolled a little to some other shots of the ballpark.
This was a great day all around, and I'm very blessed and lucky to have this time with my kids and dad. Brian and I were a little disappointed that the mascot Big Lug didn't walk the concourse or interact with fans at all. We have some more baseball fun planned soon! Final: Lugnuts 11, Hot Rods 3.
Photos property of Minoring In Baseball
Brian learns from Lugnuts
Cooley Law School Stadium-Lansing, MI: Over the weekend the kids and I traveled way down state so Brian could participate in the Lugnuts on-field baseball seminar. He had a lot of fun and learned a lot from the pros.
He started out with some outfield drills. He took some fly balls, grounders, and learned to play the ball off of the wall.
Brian's group then moved to the bullpen for some pitching practice. His age group up here uses a pitching machine, so this was his first experience on the mound.
After his pitching stint, his group moved to the infield for some work. Lugnuts player Tom Robson was running things there, and gave the kids some good instruction. Brian did a great job, and this is the best I've seen him field ground balls all season.
Brian is a runner, so it was no surprise he enjoyed the base running aspect of the seminar so much. He learned some things we haven't touched on at his level yet, like leading off and stealing. The last station was hitting, the best aspect of his game. Unfortunately, time ran out, and he didn't get a chance to hit. He was disappointed, so I threw a few to him in the outfield before we left so he could show off a bit. He had one of the Lugnuts sign his ball and got his picture taken, also.
After the seminar the kids were able to play on the park and bouncy house stuff, so all was good. This was a great experience for Brian, as he learned a lot and had fun doing it. I hope I can get him into more things like this in the future. I also apologize for this post, as it was done entirely on my iPhone since my computer is jacked.
Here is a video of the outfield station:
Photos and video property of Minoring In Baseball
Little League Season Ends
Every year it seems like the baseball season just flies by, and 2015 was no exception. I feel blessed and honored that I had the opportunity to coach the Rookie Division Cubs this season. They are a great bunch of kids, and it's always special to be able to spend time coaching your own son or daughter. I'm really proud of Brian this season, as he adjusted well from tee ball to hitting off of the machine, especially since it tosses the ball all over the place. He made some nice plays in the field, and learned about being a good teammate. I saw a lot of growth in our other players, also, and that's always very satisfying. As long as the kids learned the game and had fun to the point of wanting to play again next season, then I'll call this one a success. We ended the season on a positive note also, as the team came back to beat the Yankees 4-3 in the final inning. I really give the Sault Area Little League credit, too, as we're continuing clinics even after the official season is over. Sometimes Brian prefers just working one-on-one with me, so we end up doing that, also. I'm still hoping we'll be relocated by next season someplace warmer so we can get going sooner in the year, but if not we'll make do where we're at.
Video of our sliding drill from the last practice:
Photos and video property of Minoring In Baseball
Baseball or Hockey for Kivett
MiLB.com did a great story on West Michigan Whitecaps outfielder Ross Kivett. Growing up on Ohio, Kivett started playing hockey at an early age, and only started baseball when he was 12. He's having a nice season in West Michigan, so it looks like he made the right decision, and that's not taking anything away from the great sport of hockey. I know for me living here in Michigan, hockey is huge (especially the town I'm living in right now). For me as a kid, the only two sports were baseball and hockey. It made sense, too, playing baseball all summer and hockey all winter, and they continue to be the true sport loves of my life. I really don't think that kids play multiple sports like I did as a kid, and it's too bad. You can read the full article on Ross HERE.
Photo property of Minoring In Baseball
STAR WARS NIGHT-Episode V: The Umpire Strikes Out
West Michigan Whitecaps vs Bowling Green Hot Rods (Midwest League)
Fifth Third Ballpark-Comstock Park, MI: Oh, it's that time of the year, again, when my little Nerf-Herders and I head down to Fifth Third Ballpark for Star Wars Night. We got to meet old favorites like the Stormtroopers and Darth Vader, as well as a newbie like Sabine Wren from Star Wars Rebels. The one thing I was disappointed with was that there was no Boba Fett!! How could the most feared bounty hunter in the galaxy not make an appearance?
After we mingled with members of the Galactic Empire and Rebellion, we were able to take a stroll around the warning track of Fifth Third Ballpark. Personally, I never turn down an opportunity to walk around on a professional baseball field. Jedi Franky welcomed us onto the field, and was able to get a few good pics of the boys.
With everything going on, we almost forgot we had a ballgame to watch. This was a pitcher's duel for certain. On the mound for the 'Caps, A.J. Ladwig gave up an early solo home run, but settle in and pitched a nice game. He went 6.1 innings, only giving up two earned runs, and striking out two. Gage Smith would come in and earn the save.
Offensively, West Michigan was led by catcher Arvicent Perez, who went 3-3 on the night, including an RBI. Both Rashad Brown and Michael Gerber went 2-4, respectively, with Gerber earning an RBI. Garrett Mattlage scored on a wild pitch, and Zach Shepherd walked and scored on a throwing error. Final: Whitecaps 3, Hot Rods 2.
After the game we were treated to some fireworks, which capped off a fantastic night. Just one more game where I feel lucky and blessed to be able to spend time with my kids and dad. We're not sure when our next game will be, but we'll be sure to make it's a good one.
And one more photo we bought from MI Unlimited Photography. For some reason all three of us look like we were just captured and are about to be brought before the Emperor. I guess we're just tired from travel and fun.
Photos and video property of Minoring In Baseball
Back To The Loons
Great Lakes Loons vs. West Michigan Whitecaps (Midwest League)
Dow Diamond-Midland, MI: This month is the 30th anniversary of one of my favorite films of all time, Back To The Future. When we found out that the Great Lakes Loons were hosting a BTTF night, Brian and I jumped in the van and drove 88 mph downstate to take in the game. As soon as we entered the gate, we found what we were looking for: the BTTF car; the time machine; the DeLorean. Just to be able to see the car that was in he movie was amazing, but Brian got a special treat. By making a donation to the Michael J. Fox Foundation, he was able to get into the car. 'Future boy' hammed it up a bit, and we got some great photos!
Bri earned his DeLorean drivers license, too:
Also a little video of Brian in the time machine. I would love to take him on a trip back to 1985:
Great Scott!!!! Three generations of baseball fans:
After we were done checking the car out, we headed down to the visitor's dugout to try for some Whitecaps autographs. Brian really wanted to get Joey Pankake to sign his card, but he didn't play this game. He did get his hat signed by Zach Shepherd and Franklin Navarro, though, and they were both very nice to him.As for the actual baseball game that took place, the Loons jumped out to a 1-0 lead when first baseman Justin Chigbogu hit a bomb over the right field fence that hasn't landed yet. He went 2-4 on the night. Great Lakes then went up 2-0 on a Jimmy Allen RBI that scored Federico Celli. Allen was 1-3 for the game, and Celli 2-4.
We also spent some time at Lou E's Lookout, playing on the playground and hanging out with mascots Lou E. Loon and Ral E. Camel.
Whoa, this is heavy, but while we were in the Lookout, the Whitecaps started their comeback. The 'Caps scored five unanswered runs, and needed only two RBI's to do it. Michael Gerber got West Michigan on the board, when he scored on a wild pitch after hitting a triple. Gerber went 1-3 with an RBI, while Derek Hill led the way offensively, going 2-4 with the other RBI. David Gonzalez also went 2-4 with two runs scored.
A view from out seats. There simply is no bad seat at Dow Diamond, it's such a great ballpark. And this moon was amazing, too!
On the mound, Artie Lewicki earned the win for West Michigan, allowing two runs on seven hits. Gabe Hemmer and Johan Belisario picked up the hold and save, throwing just over three scoreless innings. Kevin Guzman took the loss for the Loons. Another fun game, and feeling very blessed to be able to experience this with my son and dad. With a long drive ahead of us, 'future boy' and I made like a tree and got out of there. We have another game planned soon, but we'll see how the weather holds up. Final: Loons 2, Whitecaps 5.
And another YouTube video of the game:
Photos and videos property of Minoring In Baseball
Mid-Season Report
Brian has had a few more games in this season, and is really adapting well from tee ball to hitting off of the pitching machine. He's getting hits on a regular basis, and has made some nice plays in the field. Most important of all, he's having fun and learning a lot. We give the kids an opportunity to play every position, so he's seen the ball come off the bat at about every angle.
The posted photos are from two different games, all taken by his sister Lily, who has become his official photographer. His brother Trevor has also been helping out with the team, especially with the catchers. It's always good to have us all together, and they can easily be bribed with Dairy Queen after the games. I feel very blessed to be able to coach Brian and the Cubs this season.
Also getting it done in the field:
Photos property of Minoring In Baseball
Sounds Like Fun
Nashville Sounds vs. Oklahoma City Dodgers (Pacific Coast League)
First Tennessee Park-Nashville, TN: Over the weekend my best friend was lucky enough to take in a couple of games down in Nashville. He was also nice enough to supply me with some photos of his experience, and it definitely looks like a great place to see a ballgame. The scoreboard looks especially unique, and fits into the theme of Nashville so much, and just one of the reasons I love minor league baseball. The Sounds hosted the Oklahoma City Dodgers both nights he was there, winning 3-2 on Friday, and 7-2 on Saturday. The top photo, and the one below are from Friday nights game.
The rest of them below are from Saturday. Thanks again to my friend for providing these pictures. First Tennessee Park is definitely one that I need to see for myself one day.
Rain can't spoil a day at the Beach (Bums)
Traverse City Beach Bums vs. Joliet Slammers (Frontier League)
Wuerfel Park-Traverse City, MI: The summer of rain continues, but we didn't let it ruin our baseball fun over the weekend. Although it rained most of the weekend, the weather cleared up enough to take in our first Beach Bums game of the season. Our experience started off on a good note, as Brian got a game ball from the Joliet Slammers before the game even started. I guess it's good to make the right friends, as he was chatting with the guys in the bullpen.
Here's a video I took by mistake, as I thought that the photo mode was on the phone:
The game was a good one for the home team. The Bums scored three runs in the second inning, and never looked back on their way to victory. Offensively they were led by Jay Austin, who had four hits and was just a home run shy of hitting for the cycle. Jeff DeBlieux pitching in with a triple and 2 RBI's, while Jake Rhodes and Greg Harisis each had hits. In the fifth inning, Graham Ramos hit and RBI single, and then scored on a double by Yazy Arbelo. On the bump, pitcher Kramer Champlin threw seven strong innings for the win, allowing four hits and no runs. Final score: Beach Bums 5, Slammers 1.
This is also the first time I've seen a mascot fight break out…
After the game, Brian was able to run the bases of Wuerfel Park.
After he ran the bases, he met up with a couple of the Slammers players to thank them again for the baseball. He was going to stand in line for the Beach Bum autographs, but he was tired and we still had a long drive ahead of us. This was a fun game, and the impending rain kept it a very small crowd. We were lucky that the rain held off for us, and I'm hoping to get back to TC soon. It's a good ballpark to visit since one our way down state one way or another.
Here's another video from the game:
Photos and videos property of Minoring In Baseball


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Man charged with dangerous driving
BARRE A Northfield Falls man is accused of driving dangerously with his 2-year-old daughter in the car.
Jesse L. Hodgdon, 39, pleaded not guilty to charges of careless or negligent operation and child cruelty on a child less than 10 years old, both misdemeanors, in Washington County criminal court Thursday. If convicted, he faces a maximum of three years in prison and a $1,500 fine.
According to the police affidavit, witnesses saw Hodgdon tailgate a slow vehicle on Route 12 heading toward Berlin. When the vehicle turned onto Muzzy Road, Hodgdon allegedly got close to the car and laid on the horn, then swerved around him, missing the turning car by only a few inches.
A witness said Hodgdon then passed another slow car near the Econo Lodge and nearly had a head-on collision with another vehicle.
The witnesses called police, who located Hodgdon at the Cumberland Farms in Berlin. Police said they saw Hodgdons daughter in a car seat in the locked vehicle, which was not running although the temperature was around 36 degrees. They also said Hodgdon would not have been able to see the vehicle from inside the store.MORE IN This Just In
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Are you Allan J Bieber?Claim your profile
Publications (39)189.05 Total impact
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ABSTRACT: Object: Despite a promising outlook, existing intraspinal microstimulation (ISMS) techniques for restoring functional motor control after spinal cord injury are not yet suitable for use outside a controlled laboratory environment. Thus, successful application of ISMS therapy in humans will require the use of versatile chronic neurostimulation systems. The objective of this study was to establish proof of principle for wireless control of ISMS to evoke controlled motor function in a rodent model of complete spinal cord injury. Methods: The lumbar spinal cord in each of 17 fully anesthetized Sprague-Dawley rats was stimulated via ISMS electrodes to evoke hindlimb function. Nine subjects underwent complete surgical transection of the spinal cord at the T-4 level 7 days before stimulation. Targeting for both groups (spinalized and control) was performed under visual inspection via dorsal spinal cord landmarks such as the dorsal root entry zone and the dorsal median fissure. Teflon-insulated stimulating platinum-iridium microwire electrodes (50 μm in diameter, with a 30- to 60-μm exposed tip) were implanted within the ventral gray matter to an approximate depth of 1.8 mm. Electrode implantation was performed using a free-hand delivery technique (n = 12) or a Kopf spinal frame system (n = 5) to compare the efficacy of these 2 commonly used targeting techniques. Stimulation was controlled remotely using a wireless neurostimulation control system. Hindlimb movements evoked by stimulation were tracked via kinematic markers placed on the hips, knees, ankles, and paws. Postmortem fixation and staining of the spinal cord tissue were conducted to determine the final positions of the stimulating electrodes within the spinal cord tissue. Results: The results show that wireless ISMS was capable of evoking controlled and sustained activation of ankle, knee, and hip muscles in 90% of the spinalized rats (n = 9) and 100% of the healthy control rats (n = 8). No functional differences between movements evoked by either of the 2 targeting techniques were revealed. However, frame-based targeting required fewer electrode penetrations to evoke target movements. Conclusions: Clinical restoration of functional movement via ISMS remains a distant goal. However, the technology presented herein represents the first step toward restoring functional independence for individuals with chronic spinal cord injury.Journal of Neurosurgery 12/2014; 123(1):1-11. DOI:10.3171/2014.10.JNS132370 · 3.74 Impact Factor
Article: Frequency-dependent functional neuromodulatory effects on the motor network by ventral lateral thalamic deep brain stimulation in swine[Show abstract] [Hide abstract]
ABSTRACT: Thalamic deep brain stimulation (DBS) is an FDA-approved neurosurgical treatment for medication-refractory essential tremor. Its therapeutic benefit is highly dependent upon stimulation frequency and voltage parameters. We investigated these stimulation parameter-dependent effects on neural network activation by performing functional magnetic resonance imaging (fMRI) during DBS of the ventral lateral (VL) thalamus and comparing the blood oxygenation level-dependent (BOLD) signals induced by multiple stimulation parameter combinations in a within-subject study of swine. Low (10 Hz) and high (130 Hz) frequency stimulation was applied at 3, 5, and 7 V in the VL thalamus of normal swine (n = 5). We found that stimulation frequency and voltage combinations differentially modulated the brain network activity in the sensorimotor cortex, the basal ganglia, and the cerebellum in a parameter-dependent manner. Notably, in the motor cortex, high frequency stimulation generated a negative BOLD response, while low frequency stimulation increased the positive BOLD response. These frequency-dependent differential effects suggest that the VL thalamus is an exemplary target for investigating functional network connectivity associated with therapeutic DBS.NeuroImage 10/2014; 105. DOI:10.1016/j.neuroimage.2014.09.064 · 6.36 Impact Factor
Article: A neurochemical closed-loop controller for deep brain stimulation: Toward individualized smart neuromodulation therapies[Show abstract] [Hide abstract]
ABSTRACT: Current strategies for optimizing deep brain stimulation (DBS) therapy involve multiple postoperative visits. During each visit, stimulation parameters are adjusted until desired therapeutic effects are achieved and adverse effects are minimized. However, the efficacy of these therapeutic parameters may decline with time due at least in part to disease progression, interactions between the host environment and the electrode, and lead migration. As such, development of closed-loop control systems that can respond to changing neurochemical environments, tailoring DBS therapy to individual patients, is paramount for improving the therapeutic efficacy of DBS. Evidence obtained using electrophysiology and imaging techniques in both animals and humans suggests that DBS works by modulating neural network activity. Recently, animal studies have shown that stimulation-evoked changes in neurotransmitter release that mirror normal physiology are associated with the therapeutic benefits of DBS. Therefore, to fully understand the neurophysiology of DBS and optimize its efficacy, it may be necessary to look beyond conventional electrophysiological analyses and characterize the neurochemical effects of therapeutic and non-therapeutic stimulation. By combining electrochemical monitoring and mathematical modeling techniques, we can potentially replace the trial-and-error process used in clinical programming with deterministic approaches that help attain optimal and stable neurochemical profiles. In this manuscript, we summarize the current understanding of electrophysiological and electrochemical processing for control of neuromodulation therapies. Additionally, we describe a proof-of-principle closed-loop controller that characterizes DBS-evoked dopamine changes to adjust stimulation parameters in a rodent model of DBS. The work described herein represents the initial steps toward achieving a "smart" neuroprosthetic system for treatment of neurologic and psychiatric disorders.Frontiers in Neuroscience 06/2014; 8(8):169. DOI:10.3389/fnins.2014.00169 · 3.66 Impact Factor
Article: Implementation of a Chronic Unilateral Intraparenchymal Drug Delivery System in a Swine Model.[Show abstract] [Hide abstract]
ABSTRACT: Systemic delivery of pharmacologic agents has led to many significant advances in the treatment of neurologic and psychiatric conditions. However, this approach has several limitations, including difficulty penetrating the blood-brain barrier and enzymatic degradation prior to reaching its intended target. Here, we describe the testing of a system allowing intraparenchymal (IPa) infusion of therapeutic agents directly to the appropriate anatomical targets, in a swine model. Five male pigs underwent 3.0 T magnetic resonance (MR) guided placement of an IPa catheter into the dorso-medial putamen, using a combined system of the Leksell Stereotactic Arc, a Mayo-developed MRI-compatible pig head frame, and a custom-designed Fred Haer Company (FHC) delivery system. Our results show hemi-lateral coverage of the pig putamen is achievable from a single infusion point and that the volume of the bolus detected in each animal is uniform (1544±420mm3). The IPa infusion system is designed to isolate the intracranial catheter from bodily-induced forces while delivering drugs and molecules into the brain tissue by convection-enhanced delivery, with minimal-to-no catheter track backflow. This study presents an innovative IPa drug delivery system, which includes a sophisticated catheter and implantable pump designed to deliver drugs and various molecules in a precise and controlled manner with limited backflow. It also demonstrates the efficacy of the delivery system, which has the potential to radically impact the treatment of a wide range of neurologic conditions. Lastly, the swine model used here has certain advantages for translation into clinical applications.Journal of Neuroscience Methods 01/2014; 227. DOI:10.1016/j.jneumeth.2014.01.029 · 2.05 Impact Factor
Article: Large Animal Model for Development of Functional Restoration Paradigms Using Epidural and Intraspinal Stimulation[Show abstract] [Hide abstract]
ABSTRACT: Restoration of movement following spinal cord injury (SCI) has been achieved using electrical stimulation of peripheral nerves and skeletal muscles. However, practical limitations such as the rapid onset of muscle fatigue hinder clinical application of these technologies. Recently, direct stimulation of alpha motor neurons has shown promise for evoking graded, controlled, and sustained muscle contractions in rodent and feline animal models while overcoming some of these limitations. However, small animal models are not optimal for the development of clinical spinal stimulation techniques for functional restoration of movement. Furthermore, variance in surgical procedure, targeting, and electrode implantation techniques can compromise therapeutic outcomes and impede comparison of results across studies. Herein, we present a protocol and large animal model that allow standardized development, testing, and optimization of novel clinical strategies for restoring motor function following spinal cord injury. We tested this protocol using both epidural and intraspinal stimulation in a porcine model of spinal cord injury, but the protocol is suitable for the development of other novel therapeutic strategies. This protocol will help characterize spinal circuits vital for selective activation of motor neuron pools. In turn, this will expedite the development and validation of high-precision therapeutic targeting strategies and stimulation technologies for optimal restoration of motor function in humans.PLoS ONE 12/2013; 8(12):e81443. DOI:10.1371/journal.pone.0081443 · 3.23 Impact Factor
Article: Quantitative trait loci analysis reveals candidate genes implicated in regulating functional deficit and CNS vascular permeability in CD8 T cell-initiated blood–brain barrier disruption[Show abstract] [Hide abstract]
ABSTRACT: Blood--brain barrier (BBB) disruption is an integral feature of numerous neurological disorders. However, there is a relative lack of knowledge regarding the underlying molecular mechanisms of immune-mediated BBB disruption. We have previously shown that CD8 T cells and perforin play critical roles in initiating altered permeability of the BBB in the peptide-induced fatal syndrome (PIFS) model developed by our laboratory. Additionally, despite having indistinguishable CD8 T cell responses, C57BL/6J (B6) mice are highly susceptible to PIFS, exhibiting functional motor deficits, increased astrocyte activation, and severe CNS vascular permeability, while 129S1/SvImJ (129S1) mice remain resistant. Therefore, to investigate the potential role of genetic factors, we performed a comprehensive genetic analysis of (B6 x 129S1) F2 progeny to define quantitative trait loci (QTL) linked to the phenotypic characteristics stated above that mediate CD8 T cell-initiated BBB disruption. Using single nucleotide polymorphism (SNP) markers and a 95% confidence interval, we identified one QTL (PIFS1) on chromosome 12 linked to deficits in motor function (SNP markers rs6292954, rs13481303, rs3655057, and rs13481324, LOD score = 3.3). In addition we identified a second QTL (PIFS2) on chromosome 17 linked to changes in CNS vascular permeability (SNP markers rs6196216 and rs3672065, LOD score = 3.7). The QTL critical intervals discovered have allowed for compilation of a list of candidate genes implicated in regulating functional deficit and CNS vascular permeability. These genes encode for factors that may be potential targets for therapeutic approaches to treat disorders characterized by CD8 T cell-mediated BBB disruption.BMC Genomics 10/2013; 14(1):678. DOI:10.1186/1471-2164-14-678 · 3.99 Impact Factor
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ABSTRACT: Electrochemical techniques have long been utilized to investigate chemical changes in the neuronal microenvironment. Preclinical models have demonstrated the successful monitoring of changes in various neurotransmitter systems in vivo with high temporal and spatial resolution. The expansion of electrochemical recording to humans is a critical yet challenging goal to elucidate various aspects of human neurophysiology and to create future therapies. We have designed a novel device named the WINCS (Wireless Instantaneous Neurotransmitter Concentration Sensing) system that combines rapid scan voltammetry with wireless telemetry for highly resolved electrochemical recording and analysis. WINCS utilizes fast-scan cyclic voltammetry and fixed potential amperometry for in vivo recording and has demonstrated high temporal and spatial resolution in detecting changes in extracellular levels of a wide range of analytes including dopamine, adenosine, glutamate, serotonin, and histamine. Neurochemical monitoring in humans represents a new approach to understanding the neurophysiology of the central nervous system, the neurobiology of numerous diseases, and the underlying mechanism of various neurosurgical therapies. This article addresses the current understanding of electrochemistry, its application in humans, and future directions.Stereotactic and Functional Neurosurgery 02/2013; 91(3):141-147. DOI:10.1159/000345111 · 2.02 Impact Factor
Article: A Novel and Selective Poly (ADP-Ribose) Polymerase Inhibitor Ameliorates Chemotherapy-Induced Painful Neuropathy[Show abstract] [Hide abstract]
ABSTRACT: Chemotherapy-induced neuropathy is the principle dose limiting factor requiring discontinuation of many chemotherapeutic agents, including cisplatin and oxaliplatin. About 30 to 40% of patients receiving chemotherapy develop pain and sensory changes. Given that poly (ADP-ribose) polymerase (PARP) inhibition has been shown to provide neuroprotection, the current study was developed to test whether the novel PARP inhibitor compound 4a (analog of ABT-888) would attenuate pain in cisplatin and oxaliplatin-induced neuropathy in mice. An established chemotherapy-induced painful neuropathy model of two weekly cycles of 10 intraperitoneal (i.p.) injections separated by 5 days rest was used to examine the therapeutic potential of the PARP inhibitor compound 4a. Behavioral testing using von Frey, paw radiant heat, cold plate, and exploratory behaviors were taken at baseline, and followed by testing at 3, 6, and 8 weeks from the beginning of drug treatment. Cisplatin-treated mice developed heat hyperalgesia and mechanical allodynia while oxaliplatin-treated mice exhibited cold hyperalgesia and mechanical allodynia. Co-administration of 50 mg/kg or 25 mg/kg compound 4a with platinum regimen, attenuated cisplatin-induced heat hyperalgesia and mechanical allodynia in a dose dependent manner. Similarly, co-administration of 50 mg/kg compound 4a attenuated oxaliplatin-induced cold hyperalgesia and mechanical allodynia. These data indicate that administration of a novel PARP inhibitor may have important applications as a therapeutic agent for human chemotherapy-induced painful neuropathy.PLoS ONE 01/2013; 8(1):e54161. DOI:10.1371/journal.pone.0054161 · 3.23 Impact Factor
Article: Therapeutics to Promote CNS Repair: A Natural Human Neuron-Binding IgM Regulates Membrane-Raft Dynamics and Improves Motility in a Mouse Model of Multiple Sclerosis[Show abstract] [Hide abstract]
ABSTRACT: We have discovered a role for natural autoantibodies in central nervous system repair, remyelination and axon protection. These natural human antibodies are of the immunoglobulin M (IgM) isotype, and they bind to the surface of neural cells. The epitope of the antibody includes sialic acid because treatment with sialidase disrupts the binding. A fully human recombinant form of one of these IgMs, rHIgM12, has the same properties as the serum-derived IgM. rHIgM12 enhanced polarized axonal outgrowth from primary neurons when presented as a substrate in vitro and improved motor functions in chronically Theiler's virus-infected SJL mice, a model of MS. rHIgM12 bound to neuronal surfaces and induced cholesterol and ganglioside (GM1) clustering, indicating that rHIgM12 functions through a mechanism of axonal membrane stabilization. Our work demonstrates that a natural human neuron-binding IgM can regulate membrane domain dynamics. This antibody has the potential to improve neurologic disease.Journal of Clinical Immunology 09/2012; 33(S1). DOI:10.1007/s10875-012-9795-8 · 3.18 Impact Factor
Article: Deletion of Beta-2-Microglobulin Ameliorates Spinal Cord Lesion Load and Promotes Recovery of Brainstem NAA Levels in a Murine Model of Multiple Sclerosis[Show abstract] [Hide abstract]
ABSTRACT: We used genetic deletion of β2-microglobulin to study the influence of CD8(+) T cells on spinal cord demyelination, remyelination, axonal loss and brainstem N-acetyl aspartate levels during the acute and chronic phases of Theiler's murine encephalomyelitis virus (TMEV) infection. We used β2m(-/-) and β2m(+/+) B10.Q mice (of H-2(q) background) normally susceptible to TMEV-induced demyelination. Over the disease course, β2m(+/+) mice had increasing levels of demyelination and minimal late-onset remyelination. In contrast, β2m(-/-) mice had steady levels of demyelination from 45-390 dpi and remyelination was extensive and more complete. Early in the disease, brainstem NAA levels drop in both strains, but accordingly with remyelination and axonal preservation, NAA recover in β2m(-/-) mice despite equivalent brainstem pathology. At 270 dpi, β2m(+/+) mice had significantly fewer spinal cord axons than β2m(-/-) mice (up to 28% less). In addition, β2m(+/+) mice lost axons of all calibers, whereas β2m(-/-) mice had a modest loss of only medium- and large-caliber axons. This study further supports the hypothesis that CD8(+) T cells are involved in demyelination, and axonal loss following Theiler's virus-induced demyelination.Brain Pathology 02/2012; 22(5):698-708. DOI:10.1111/j.1750-3639.2012.00576.x · 3.84 Impact Factor
Article: Evidence for the Role of B Cells and Immunoglobulins in the Pathogenesis of Multiple Sclerosis[Show abstract] [Hide abstract]
ABSTRACT: The pathogenesis of multiple sclerosis (MS) remains elusive. Recent reports advocate greater involvement of B cells and immunoglobulins in the initiation and propagation of MS lesions at different stages of their ontogeny. The key role of B cells and immunoglobulins in pathogenesis was initially identified by studies in which patients whose fulminant attacks of demyelination did not respond to steroids experienced remarkable functional improvement following plasma exchange. The positive response to Rituximab in Phase II clinical trials of relapsing-remitting MS confirms the role of B cells. The critical question is how B cells contribute to MS. In this paper, we discuss both the deleterious and the beneficial roles of B cells and immunoglobulins in MS lesions. We provide alternative hypotheses to explain both damaging and protective antibody responses.Neurology Research International 09/2011; 2011:780712. DOI:10.1155/2011/780712
Article: Transgenic Expression of Viral Capsid Proteins Predisposes to Axonal Injury in a Murine Model of Multiple Sclerosis[Show abstract] [Hide abstract]
ABSTRACT: We used transgenic expression of capsid antigens to Theiler's murine encephalomyelitis virus (TMEV) to study the influence of VP1, VP2 or VP2(121-130) to either protection or pathogenesis to chronic spinal cord demyelination, axonal loss and functional deficits during the acute and chronic phases of infection. We used both mice that are normally susceptible (FVB) and mice normally resistant (FVB.D(b) ) to demyelination. Transgenic expression of VP2(121-130) epitope in resistant FVB.D(b) mice caused spinal cord pathology and virus persistence because the VP2(121-130) epitope is the dominant peptide recognized by D(b) , which is critical for virus clearance. In contrast, all three FVB TMEV transgenic mice showed more demyelination, inflammation and axonal loss as compared with wild-type FVB mice, even though virus load was not increased. Motor function measured by rotarod showed weak correlation with total number of midthoracic axons, but a strong correlation with large-caliber axons (>10µm(2) ). This study supports the hypothesis that expression of viral capsid proteins as self influences the extent of axonal pathology following Theiler's virus-induced demyelination. The findings provide insight into the role of axonal injury in the development of functional deficits that may have relevance to human demyelinating disease.Brain Pathology 09/2011; 21(5):501-15. DOI:10.1111/j.1750-3639.2011.00474.x · 3.84 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: J. Neurochem. (2011) 119, 100–112. Mouse and human IgMs support neurite extension from primary cerebellar granule neurons. In this study using primary hippocampal and cortical neurons, we demonstrate that a recombinant human IgM, rHIgM12, promotes axon outgrowth by coupling membrane domains (lipid rafts) to microtubules. rHIgM12 binds to the surface of neuron and induces clustering of cholesterol and ganglioside GM1. After cell binding and membrane fractionation, rHIgM12 gets segregated into two pools, one associated with lipid raft fractions and the other with the detergent-insoluble cytoskeleton-containing pellet. Membrane-bound rHIgM12 co-localized with microtubules and co-immuno precipitated with β3-tubulin. rHIgM12-membrane interaction also enhanced the tyrosination of α-tubulin indicating a stabilization of new neurites. When presented as a substrate, rHIgM12 induced axon outgrowth from primary neurons. We now demonstrate that a recombinant human mAb can induce signals in neurons that regulate membrane lipids and microtubule dynamics required for axon extension. We propose that the pentameric structure of the IgM is critical to cross-link membrane lipids and proteins resulting in signaling cascades.Journal of Neurochemistry 08/2011; 119(1):100-12. DOI:10.1111/j.1471-4159.2011.07416.x · 4.28 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Platinum-based compounds are widely used and effective chemotherapeutic agents; however, sensory peripheral neuropathy is a dose-limiting and long term side effect for 20-30% of patients. A critical question is whether the mechanisms of cell death underlying clinical efficacy can be separated from the effects on neurons in order to develop strategies that prevent platinum-induced neuropathy. In rodent dorsal root ganglion neurons (DRG), cisplatin has been shown to bind and damage neuronal DNA, inducing apoptosis; however genetic manipulation in order to study mechanisms of this phenomenon in the rodent model system is costly and time-consuming. Drosophila melanogaster are commonly used to study neurological disorders, have DNA damage-apoptosis mechanisms homologous to mammalian systems, and have readily-available, inexpensive tools for rapid genetic manipulation. We therefore sought to develop adult Drosophila as a new model to study cisplatin-induced neurotoxicity. Adult Drosophila were exposed to 10, 25, 50, 100, 200 and 400 μg/ml cisplatin for 3 days and observed for fly survival and geotactic climbing behavior, cisplatin-DNA binding and cellular apoptosis. On day 3, 50 μg/ml cisplatin reduced the number of flies able to climb above 2 cm to 43% while fly survival was maintained at 92%. 100% lethality was observed at 400 μg/ml cisplatin. Whole fly platinum-genomic DNA adducts were measured and found to be comparable to adduct levels previously measured in rat DRG neurons. Brain, ovaries, kidney and heart harvested from cisplatin treated flies were stained for active caspase 3. Apoptosis was found in ovaries and brain but not in heart and kidney. Brain apoptosis was confirmed by transmission electron microscopy. Expression of the anti-apoptotic baculoviral protein, p35, in neurons using the GAL4-UAS system prevented cisplatin-induced apoptosis in the brain and restored climbing behavior. In conclusion, cisplatin-induced behavioral and apoptotic changes in Drosophila resemble those seen in mammals. Furthermore, the use of lethality and climbing assays combined with powerful gene manipulation, make Drosophila a suitable model to study mechanisms of cisplatin neurotoxicity.Neurobiology of Disease 08/2011; 43(2):330-7. DOI:10.1016/j.nbd.2011.03.022 · 5.08 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Repair of the central nervous system (CNS) constitutes an integral part of treating neurological disease and plays a crucial role in restoring CNS architecture and function. Distinct strategies have been developed to reconstruct the damaged neural tissue, with many tested preclinically in animal models. We review cell replacement-based repair strategies. By taking spinal cord injury, cerebral ischaemia and degenerative CNS disorders as examples for CNS repair, we discuss progress and potential problems in utilizing embryonic stem cells and adult neural/non-neural stem cells to repair cell loss in the CNS. Nevertheless, CNS repair is not simply a matter of cell transplantation. The major challenge is to induce regenerating neural cells to integrate into the neural network and compensate for damaged neural function. The neural cells confront an environment very different from that of the developmental stage in which these cells differentiate to form interwoven networks. During the repair process, one of the challenges is neurodegeneration, which can develop from interrupted innervations to/from the targets, chronic inflammation, ischaemia, aging or idiopathic neural toxicity. Neurodegeneration, which occurs on the basis of a characteristic vascular and neural web, usually presents as a chronically progressive process with unknown aetiology. Currently, there is no effective treatment to stop or slow down neurodegeneration. Pathological changes from patients with Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis indicate a broken homeostasis in the CNS. We discuss how the blood-brain barrier and neural networks are formed to maintain CNS homeostasis and their contribution to neurodegeneration in diseased conditions. Another challenge is that some inhibitors produced by CNS injury do not facilitate the regenerating neural cells to incorporate into a pre-existing network. We review glial responses to CNS injury. Of note, the reactive astrocytes not only encompass the lesions/pathogens but may also form glial scars to impede regenerating axons from traversing the lesions. In addition, myelin debris can prevent axon growth. Myelination enables saltatory transduction of electrical impulses along axonal calibers and actually provides trophic support to stabilize the axons. Therefore, repair strategies should be designed to promote axonal growth, myelination and modulate astrocytic responses. Finally, we discuss recent progress in developing human monoclonal IgMs that regulate CNS homeostasis and promote neural regeneration.CNS Drugs 07/2011; 25(7):555-73. DOI:10.2165/11587830-000000000-00000 · 5.11 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Immunoglobulins (Ig) or antibodies are heavy plasma proteins, with sugar chains added to amino acid residues by N-linked glycosylation and occasionally by O-linked glycosylation. The versatility of antibodies is demonstrated by the various functions that they mediate such as neutralization, agglutination, fixation with activation of complement and activation of effector cells. In addition to this plethora of functions, some antibodies express enzymatic activity. Antibodies endowed with enzymatic properties have been described in human autoimmune manifestations in a variety of disorders such as autoimmune thyroiditis, systemic erythematosus (SLE), scleroderma, rheumatoid arthritis (RA), multiple sclerosis (MS) and acquired hemophilia (AH). Antibodies isolated from these conditions were able to specifically hydrolyze thyroglobulin, DNA, RNA, myelin basic protein (MBP), and factor VIII (FVIII) or factor IX (FIX), respectively. The therapeutic relevance of these findings is discussed.Journal of Autoimmunity 05/2011; 37(2):144-50. DOI:10.1016/j.jaut.2011.05.007 · 8.41 Impact Factor
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ABSTRACT: Multiple Sclerosis (MS) is a complex disease with an unknown etiology and no effective cure, despite decades of extensive research that led to the development of several partially effective treatments. Researchers have only limited access to early and immunologically active MS tissue samples, and the modification of experimental circumstances is much more restricted in human studies compared to studies in animal models. For these reasons, animal models are needed to clarify the underlying immune-pathological mechanisms and test novel therapeutic and reparative approaches. It is not possible for a single mouse model to capture and adequately incorporate all clinical, radiological, pathological and genetic features of MS. The three most commonly studied major categories of animal models of MS include: (1) the purely autoimmune experimental autoimmune/allergic encephalomyelitis (EAE); (2) the virally induced chronic demyelinating disease models, with the main model of Theiler's Murine Encephalomyelitis Virus (TMEV) infection and (3) toxin-induced models of demyelination, including the cuprizone model and focal demyelination induced by lyso-phosphatidyl choline (lyso-lecithine). EAE has been enormously helpful over the past several decades in our overall understanding of CNS inflammation, immune surveillance and immune-mediated tissue injury. Furthermore, EAE has directly led to the development of three approved medications for treatment in multiple sclerosis, glatiramer acetate, mitoxantrone and natalizumab. On the other hand, numerous therapeutical approaches that showed promising results in EAE turned out to be either ineffective or in some cases harmful in MS. The TMEV model features a chronic-progressive disease course that lasts for the entire lifespan in susceptible mice. Several features of MS, including the role and significance of axonal injury and repair, the partial independence of disability from demyelination, epitope spread from viral to myelin epitopes, the significance of remyelination has all been demonstrated in this model. TMEV based MS models also feature several MRI findings of the human disease. Toxin-induced demyelination models has been mainly used to study focal demyelination and remyelination. None of the three main animal models described in this review can be considered superior; rather, they are best viewed as complementary to one another. Despite their limitations, the rational utilization and application of these models to address specific research questions will remain one of the most useful tools in studies of human demyelinating diseases.Pathophysiology 02/2011; 18(1):21-9. DOI:10.1016/j.pathophys.2010.04.004
Article: Transient Receptor Potential Vanilloid 1 is essential for cisplatin-induced heat hyperalgesia in mice[Show abstract] [Hide abstract]
ABSTRACT: Cisplatin is primarily used for treatment of ovarian and testicular cancer. Oxaliplatin is the only effective treatment for metastatic colorectal cancer. Both are known to cause dose related, cumulative toxic effects on the peripheral nervous system and thirty to forty percent of cancer patients receiving these agents experience painful peripheral neuropathy. The mechanisms underlying painful platinum-induced neuropathy remain poorly understood. Previous studies have demonstrated important roles for TRPV1, TRPM8, and TRPA1 in inflammation and nerve injury induced pain. In this study, using real-time, reverse transcriptase, polymerase chain reaction (RT-PCR), we analyzed the expression of TRPV1, TRPM8, and TRPA1 induced by cisplatin or oxaliplatin in vitro and in vivo. For in vitro studies, cultured E15 rat dorsal root ganglion (DRG) neurons were treated for up to 48 hours with cisplatin or oxaliplatin. For in vivo studies, trigeminal ganglia (TG) were isolated from mice treated with platinum drugs for three weeks. We show that cisplatin and oxaliplatin-treated DRG neurons had significantly increased in TRPV1, TRPA1, and TRPM8 mRNA expression. TG neurons from cisplatin treated mice had significant increases in TRPV1 and TRPA1 mRNA expression while oxaliplatin strongly induced only TRPA1. Furthermore, compared to the cisplatin-treated wild-type mice, cisplatin-treated TRPV1-null mice developed mechanical allodynia but did not exhibit enhancement of noxious heat- evoked pain responses. Immunohistochemistry studies showed that cisplatin-treated mice had no change in the proportion of the TRPV1 immunopositive TG neurons. These results indicate that TRPV1 and TRPA1 could contribute to the development of thermal hyperalgesia and mechanical allodynia following cisplatin-induced painful neuropathy but that TRPV1 has a crucial role in cisplatin-induced thermal hyperalgesia in vivo.Molecular Pain 03/2010; 6(1):15. DOI:10.1186/1744-8069-6-15 · 3.65 Impact Factor
Article: Allelic variation in the Tyk2 and EGF genes as potential genetic determinants of CNS repair[Show abstract] [Hide abstract]
ABSTRACT: The potential for endogenous remyelination and axonal protection can be an important factor in determining disease outcome in demyelinating diseases like multiple sclerosis. In many multiple sclerosis (MS) patients CNS repair fails or is incomplete whereas in others the disease is accompanied by extensive repair of demyelinated lesions. We have described significant differences in the ability of two strains of mice to repair CNS damage following Theiler's virus-induced demyelination: FVB/NJ (FVB) mice repair damaged myelin spontaneously and completely, whereas B10.D1-H2(q)/SgJ (B10.Q) mice are deficient in the repair process. A QTL analysis was performed to identify genetic loci that differentially regulate CNS repair following chronic demyelination in these strains and two QTL were detected: one on chromosome 3 with a LOD score of 9.3 and a second on chromosome 9 with a LOD score of 14.0. The mouse genes for epidermal growth factor (EGF) and Tyk2 are encoded within the QTL on chromosomes 3 and 9, respectively. Sequence polymorphisms between the FVB and B10.Q strains at both the EGF and Tyk2 loci define functional variations consistent with roles for these genes in regulating myelin repair. EGF is a key regulator of cell growth and development and we show a sevenfold increase in EGF expression in FVB compared to B10.Q mice. Tyk2 is a Janus kinase that plays a central role in controlling the T(H)1 immune response and we show that attenuation of Tyk2 function correlates with enhanced CNS repair.Proceedings of the National Academy of Sciences 01/2010; 107(2):792-7. DOI:10.1073/pnas.0906589107 · 9.67 Impact Factor
Article: Brainstem 1H Nuclear Magnetic Resonance (NMR) spectroscopy: Marker of demyelination and repair in spinal cord[Show abstract] [Hide abstract]
ABSTRACT: Measuring in vivo spinal cord injury and repair remains elusive. Using magnetic resonance spectroscopy (MRS) we examined brainstem N-acetyl-aspartate (NAA) as a surrogate for spinal cord injury in two mouse strains with different reparative phenotypes following virus-induced demyelination. Swiss Jim Lambert (SJL) and Friend Virus B (FVB) mice progressively demyelinate with axonal loss. FVB mice demyelinate similarly but eventually remyelinate coincident with functional recovery. Brainstem NAA levels drop in both but recover in FVB mice. Chronically infected SJL mice lost 30.5% of spinal cord axons compared to FVB mice (7.3%). In remyelination-enhancing or axon-preserving clinical trials, brainstem MRS may be a viable endpoint to represent overall spinal cord dysfunction.Annals of Neurology 10/2009; 66(4):559-64. DOI:10.1002/ana.21758 · 9.98 Impact Factor
Top Journals
Mayo Clinic - Rochester
Rochester, Minnesota, United States
- Department of Neurology


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2003 Saturn Vue • 100,000 miles
My heat stopped working after I had a hose fall out of my engine compartment driving down the road. Fan motor still works and all. Just wondering where that hose goes.
November 23, 2012.
November 23, 2012.
Iam wondering also I have no clue cant see which hose it is. If you lost a heater hose then you would loose all the coolant.
Nov 23, 2012.
Nov 23, 2012.
My car has 157k on it and the coolant light came on today flashing i looked at the resivoir and it was empty filled it up and then later on that day it was empty again i looked at the ...
1 answer • 1996 Saturn SC2 • 157,000 miles
Dear SIR. Now I have some question to ask you. 1 How can i change (step)water coolant? 2 How much 1 lite oil per kilometre? 3 How can i maintain moonroof? Thanks so much
1 answer • 2006 Honda Accord • 40,000 miles
1992 Ford Tempo mileage: 65,000. My daughter has a 1992 Ford Tempo that she has been driving for about 4 years. She is very conscientious in regularly changing oil, and routinely having...
1 answer • 1992 Ford Tempo • 65,000 miles
This is about "Red" antifreeze, it's harmful attributes to engine gaskets and corrosion to all parts of the cooling and heating systems. I noticed that comments have been made on ...
1 answer • 2000 Chevrolet S-10 • 71,000 miles


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Colin Carr appears throughout the world as a soloist, chamber musician, recording artist, and teacher. He has played with major orchestras worldwide, including the Royal Concertgebouw Orchestra, The Philharmonia, Royal Philharmonic, BBC Symphony, the orchestras of Chicago, Los Angeles, Washington, Philadelphia, Montréal and all the major orchestras of Australia and New Zealand. Conductors with whom he has worked include Rattle, Gergiev, Dutoit, Elder, Skrowasczewski and Marriner. He has been a regular guest at the BBC Proms and has twice toured Australia. In the 2015-16 season he performs Fauré's Quartet No. 2 in G Minor with Chamber Music Society of Lincoln Center.
|Posted: Sep-17-2015
Live from London's Wigmore Hall. British cellist Colin Carr returns to the Wigmore Hall with pianist Thomas Sauer to perform 2 sonatas by Beethoven. He begins with a lighthearted and affectionate set of variations on an aria from Mozart's Magic Flute. Listen here.
|Posted: Nov-30-2011
"Today's cellists claim it as their own, including Briton Colin Carr who brought out all the singing qualities on his Goffriller cello. His tone was warm and sumptuous, seamlessly gliding between passages of absolute cantabile and blissful elation in its three movements."
Straits Times
|Posted: May-29-2015
The complete Solo Cello Suites of Bach recorded by one of the most extraordinary cellists of his generation, Colin Carr, winner of the Rostropovich International Cello Competition Grand Prize and the Piatigorsky Memorial Award.
Captured in minimally edited, electrically charged performances in the sparkling acoustics of Jordan Hall at the New England Conservatory of Music, Carr achieves that rare balance between personal "interpretation" and scrupulous consideration of the score that epitomizes musical performance at its loftiest. Whether it is in the driving -- at times cutting -- hell-bent energy of these interpretations, profoundly moving and gentle effusions or in Colin's exquisite taste and musical intelligence, these performances capture a truly extraordinary event.
|Posted: Apr-21-1998
|Posted: May-22-2013


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Baton Rouge Gains Another Apartment Community
BATON ROUGE, LA-Another apartment community has been opened in Baton Rouge. LDG Development of Louisville, Kentucky, has opened Mallard Crossing, an affordable housing complex consisting of 192 units on Greenwell Spring Road. The Advocate reported that the $24-million multifamily development is located beside the Greenwell Spring library.
The Weber Group, Inc. designed Mallard Crossing, which features double- and triple-bedroom units. The apartment complex is managed by Latter & Blum Property Management. For the full story, go to Commercial Property Executive .
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Catch the videos, pictures and complete GlobeSt.com coverage of RealShare APARTMENTS today.
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text:
I can see it right in front of me
But something is saying no
Granted a lot has come to me
But some major ideas still trying to make it go
Fortune force field
I can taste it, but can't drink it
I can make it when I think it
Can't mistake it, so distinctive
Man I hate this, man I dreamed it, can't believe it
I gotta let it go!
(So!) It's on for tonight
(Oh!) Hope this wall is ready for a fight
(Yo!) In this hole I'm reaching for the light
(No!) A lot of dreams are lost in the night
[Verse 1]
Why you wanna try to take my bill ticket?
I mean real wicked, I seem real livid
I've been filled with it, I mean vexed
Un-ex-pect-ted-ness, when everything is the best
I get a minute to rest, but then a nigga regrets
I gets the money but next I'm in debt (I won, what?)
I mean I lost, take green from a boss
Be the things that I dream, but they intervene they get my creme, then I'm off
(Whose they?)
They turned the motherfuckin' best position into a deposition
Dealing with that will make you wanna ex the mission
Never no checks to get to and that's the bitching
How do I maintain my autonomy
With so many leeches in this economy?
My moaning is mearly monetary
But the moment it's really gone is scary
Try to beat my high score, but I fight forward despite lawyers
An eye for an eye because my type's warrior
Never the less I inherit a mess, a big floor spill
I'm steady pushing to break down this fortune force field
[Verse 2]
It's like pulling a bad one
Get her off at the pad, then get the Jimmy to stab some
But you can't and puddy is right there
Like a, barrier or something, keeping you from her such a negative type lair
You can never pipe nair
When you've got it in front of you, wanna do, it's a pitiful nightmare
It's like making a baby
You never having it, is making you crazy
And toting a living human, it's making you weighty
Kick, kick, kick, shaking your lady
Like late in the 80's
Got my name and got to taking the stage, V
Told the people I got Satan to save me
That's why radio be hating to play me
Everything you gain only brings you pain
But the fame it fools the brain
But you regain it through Strange
Yeah, never put your guard down
Because I wanna bang, bang, bang hard now
I'm a warhound, never mistaken I kick walls down
To the ground and get applause sound
Because I got even, then I'm lard bound
Lot of dreams are lost in the night
Lot of dreams are lost in the night
[Verse 3]
Fuck your litigation
We gon' win, just a bit of waiting
Everytime that I get ahead gotta be a motherfuckin' drawback
So I'mma draw back and bang them bitches 'til they all crack
MSC look what you've done to me
Kept the first five I done for me
And you others know that Caribou Lou belong to me
You come for me
Just know we will never settle, war is what it's gonna be!
Yeah, been breaking down that fortune force field for a long time
Now I get my just due
- 1. News With Mark Alford 1 (Skit)
- 2. Straight Out the Gate
- 4. With the BS
- 5. Love 2 Dislike Me
- 6. Fortune Force Field
- 7. I'm Not a Saint
- 8. Fragile
- 9. Priorities
- 10. News With Mark Alford 2 (Skit)
- 11. Dwamn
- 12. So Dope (They Wanna)
- 13. See Me
- 14. My Haiku - Burn The World
- 15. That's My Kid
- 16. Meant To Happen
- 17. News with Mark Alford 3 (Skit) - 199193
- 18. Believe
- 19. R.I.P. Ray (Skit)
- 20. Strange 2013
- 22. Colorado
- 23. Drowning
- 24. Thizzles
- 25. Somebody Else
- 26. Feels Like Heaven
- 27. Party the Pain Away
- 28. Rockabye
- 29. Something Else Cover


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Ask Mr. Outdoors: Winter Could be Much Wetter
Q: What's your forecast for winter this year? Mild or wild? Warm or cold? Snow or no snow?
Stan and Barbara, via e-mail
A: I'd have to say it's going to be a much "better" winter than last year. By "better," I mean more snow and colder temperatures, especially above 3,000 feet. It's just a feeling I get in all my arthritic joints, plus the fact that the El Nino of last year has turned to a La Nina this year. That means we can expect a colder, wetter winter.
Do you have a question for Mr. Outdoors? E-mail him at email@example.com.
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text:
Bookeen may have a bit of a tough time getting its new Orizon e-book reader to stand out from the pack of other e-readers here at CES, but it does at least boast quite a few improvements over the company's previous Cybook Opus. That includes a 6-inch touchscreen display, built-in WiFi, Bluetooth, ePub support, and an accelerometer for portrait or landscape reading. No indication of a release date just yet, but this one should run about $250, and Bookeen still isn't quite done with the Opus -- it'll soon be available a whole range of colors.
Get it for FREE
- Key specs
- Prices
- Discussions
- Screen type E Ink
- Screen size 6 inches
- Dimensions 4.92 x 7.28 x 0.3 in
- Weight 7.97 oz
- Announced 2010-01-08


text:
1993 Pontiac Firebird • V8 2WD Automatic • 188,000 miles
My car turns on and some times, not everytime it just dies as I'm driving and will not start, I wait a few hours and it sometimes starts up again. I checked the fuel presure when its not starting and its fine so its not the pump, but I check the ignition and I don't get any fire. I changed the ignition coil and the ignition module and problem still exists and this car doesn't have a crankshaft sensor. I checked the wires to see what has fire and what has ground both when the car is on and when it doesn't wanna start and there is no difference. I lost!
January 12, 2011.
January 12, 2011.
The first thing I would check is your optisprk distributor. You need to check for spark OUT of the optispark. You can still be getting spark from your coil down to the opti and nothing out. Also chek your coil again using a gap style spark tester as I have seen them fire the lightbulb kind and still be the cause of a non starting issue. You will most likely find nothing coming out of the opti. I have replaced MANY opti's on many LT1's and Ihave seen everything from just non starting to hesitation and everythign in between. If your opti does show spark out I would then look at our starter!
Apr 5, 2012.
Apr 5, 2012.
Need torque settings on cylinderhead and big end bearings
1 answer • 2011 Chevrolet Spark • 100,000 miles
Have a vauxhall vectra last year was running ok now cant get it to start have had the battery in and out a few times also have put in new spark plugs not getting a spark
1 answer • 1996 Vauxhall Vectra
I hav a 1994 dodge ram 2500 with a 5.9 in it. recently i replaced the spark plugs bcuz when i was driving it before it would jus bog out somtimes like the spark plug wires wer bad i ...
3 answers • 1994 Dodge Ram • 123,000 miles
1995 Toyota Tercel mileage: 82,000. I am replacing the spark plugs in my Toyota Tercel. The manual calls for twin ground electrode spark plugs. The replacement from the charts says I ...
1 answer • 1995 Toyota Tercel • 82,000 miles


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As an extension of Naked for Satan, we bring you Naked in the Sky
Naked in the Sky is an open terrace with an attached bar, lounge and restaurant. We float over Fitzroy with spectacular views of the city on one side and a full length vista of Brunswick Street on the other.
You are beamed to the roof via an old lift shaft in the bowels of the building. Construction work has been carried out by the brilliant guys at Scalzo Constructions
Sukaldea – Naked Kitchen (Our Restaurant)
In keeping with the Pintxos downstairs, the food is influenced by the cuisine of the Basque country.
We offer a selection of traditional entree, side and main meals, and include a weekday lunch time special.
We also offer a variety of desserts to complete your dining experience.
Bookings can be made every lunch time, call 03 9416 2238 for reservations. At any other time, just rock up.
Bar, Lounge & Terrace
From the 15 metre long bar, you have a mouth watering choice of:
– over a dozen beers on tap
– a range of craft beers
– an extensive range of imported and in-house infused vodka
– a variety of Spanish & Australian wines
– cocktails and mocktails to suit everyones tastes
– an all new Gin menu
– coffee and tea
Medium sized plates of Basque delicacies ordered from the bar are be served to you as you sit on the roof terrace enjoying the view. No need to book, it's just a matter of coming up.


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According to the Madisonville Police report, upon arrival, officers observed Stephanie Ann Walker, 41, Earlington getting into driver's side of a vehicle. After contact was made, officers could smell a strong odor of alcohol on her breath, the report said.
The report said Walker failed a sobriety test, and she admitted to officers that she was under the influence.
Also according to the report, there were four juveniles under the age of 12 in the car.
After Walker's arrival at the Hopkins County Detention Center, officers noticed a baggie in the floorboard of the patrol car. The bag contained a small blue pill that was identified as a Diazepam.
Walker told officers that it was not hers and she didn't know where it came from, the report said.
Walker was charged with third-degree possession of controlled substance, drug unspecified, tampering with physical evidence and operating a motor vehicle under the influence of alcohol or drugs, second offense.She is being lodged in the Hopkins County Jail.
SurfKY News
Information provided by Madisonville Police Department
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LEGO models my own creation MOCpages toys shop Blood OwlBionicle
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Blood Owl
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Zoom in
My second in a line of six Toa sized self mocs, behold Owl the Owl as BLOOD OWL!!!
About this creation
Being tall for once.
Toa-thing, Half-breed, Rahi-beast, "Blood Owl"
Chaotic Neutral
Moc Status:
In an alternate universe, Owl was an average Bird-thingy until all of his friends were killed by a mass murderer named Cato. Cato had become psychotic and killed many many beings, and a revolt was formed by Owl to stop him. Owl's revolt was completely successful, and all he had to do was kill Cato in his now-unguarded base. Owl went in alone, only to find that Cato was trying to travel to an different universe through an Olmak he had collected from one of his victims!
Owl stopped him from getting through, and a major battle ensued! Cato finally knocked Owl down and was preparing to kill him, when Owl knocked down another one of Cato's prizes, a vat of Energized Protodermis. Cato grabbed Owl as they both were caught in it's flow, which ended up seeping through the portal Cato had previously opened!
Owl woke up in a grassy land, this part seemed uninhabited. After a few minutes, he realized he had been merged with Cato to form a Toa/Owl mutant, and that thankfully, he was in control. Although it appears Cato's life ended, it seems his emotions may play a part in Owl's thoughts. Owl soon met Cossy, Callan, and Davix, and has become good friends with them. He is saddened that he can no longer fly, but is quite happy that he isn't so short anymore. His new look and ignorance of the Toa Code has also earned him the nickname, Blood Owl.
Legs. I'm not sure what to make of them, but David likes them. :D
Upper body had a lot of work put into it(special feature in it if you scroll down). The arms are kinda simple, but the hands came out nicely. The head I like quite a lot, I hope you do too, Owl! :D
Action Pose 1
Action Pose 2
SPECIAL FEATURE: Remove bicycle piece on rear....
Open the rahkshi back piece and...
He's AN OWL MECH!!! Driven by this little brown fella!!!
Owl: Idea and design for cockpit created by David!! No wonder I sometimes do things for no reason at all!
Comparison with three other members of the group. :D
With Callan!
Sneak peak at the already revealed next self moc! See him on Youtube!
Later guys!
Please comment and rate if you like him! :D
Add a comment
I like it
Chaz Christinson
April 2, 2012
fantastic! i love his hands! 10 out of 10! fav moc!
I like it
Toa Naaro
September 11, 2011
i dont even need to need to see him on your youtube channel to know that it's clockwork tempest's self moc, shadow! epic moc by the way!!!!! i love that owl cockpit thing!!!!! how did david come up with it?????
I like it
Nick The Remaining
September 4, 2011
very clever idea, I love when alternate universes are used. color schemes also one of may favorites. mind making one of mine, even though both of them are titans
I like it
Toa Oblivious ,Master of Earth
September 3, 2011
I like it
Kreezon the Twilight Lord
September 3, 2011
love it. nice job, man.
I like it
Toa Phosphorus
September 2, 2011
I like it
S.T.S The Forgotten
August 31, 2011
Kewl, for some reason I have a felling that Destrin is gonna be in it. Don't know why.
I like it
Someone even less popular
August 31, 2011
I like it
Overlord Galaxus (Instant Noodles)
August 31, 2011
Slick! That torso, hands and head are awesome! nice idea of merging!
I like it
sorajel bionicle
August 31, 2011
awesome colour scheme and hey
I like it
Ben Cossy
August 31, 2011
Like I said on skype, this is freaking awesome! I totally LOVE that Owl Mech idea and great work with his wing like hands and amazing work with the torso! Great work mate ;)
I like it
JPfan65 Studios
August 30, 2011
=O ! I Just...Am Speechles...
I like it
Legofreak2444 ~
August 30, 2011
Very cool! Is 2444 Toa size right now or is he smaller? :P
I like it
Ahpolki Ihu
August 30, 2011
Lemme guess, Toa Shadow? :P
I like it
Alien Entity
August 30, 2011
owl within an owl! OWL-CEPTION
I like it
Liam Covey
August 30, 2011
Awesome stuff here. The simplicity of the arms and legs are nice, the body is flippin' sweet, and the colors are great. 5/5!
I like it
Chopperskull (Leader of air)
August 30, 2011
CLEVER ! Man this is one awesome moc ! Owl is evil looking. I did not expect it to be a mech, but not only that, who would have known the driver is an owl ! Man this is epic ! I love the hands and legs for some reason. I'm guessign the next one is Toa Shadow ? Although it could always be somebody else.
I like it
Alpha AI
August 30, 2011
That's a neat fusion! I wonder how the story will be affected by this new character...
I like it
Owen Netzer , Bishop of the White Night
August 30, 2011
Nice rendition, a bit odd to see an Owl without wings, but hey. Originality, right?
I like it
Cody G
August 30, 2011
Interesting take on Owl! Nicely done!
I like it
Shadow Toa
August 30, 2011
Epic! I wonder who the others are! ,Shadow
I like it
Raviel Ze MOCist!
August 30, 2011
Very good!That looks alot like my background.:P
I made it
Callan Lord of Fire
August 30, 2011
Quoting Deus Otiosus
Opening brickshelf accounts would be a great temporary solution for the MOCpages crysis. Just for hostingg, of course. MOCpages commenting and group system beats all other LEGO pages.
Ah, sorry you can't see it. I'll see if I can post it on Brickshelf for you! :D
I like it
Rahkshi Party
August 30, 2011
Mocpages dos'nt seem to be working, THE DESCRIPTIONS SOUND AWESOME THOUGH!
Deus Otiosus
August 30, 2011
Opening brickshelf accounts would be a great temporary solution for the MOCpages crysis. Just for hostingg, of course. MOCpages commenting and group system beats all other LEGO pages.
I like it
Owl The Owl
August 30, 2011
BWAHAHA!! Thats wicked awesome! Love the backstory. Merging two Self-MOCs into one has to be the best idea ever. Thanks So much! The Owl-mech part is such a great idea. Awesome!!!!
Caleb Lang
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2,532 visitors
26 comments
August 30, 2011
Self mocs/chibis (68)
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text:
Acrylate Based Eyeliner Prototype
Published August 2, 2013
Phase A
|Syntran PC 5620 (Interpolymer) (Styrene /acrylates / ammonium methacrylate copolymer)
Phase B
|Covarine Black WS 9199 Dispersion (Sensient) (Carbon black, water, glycerin, xanthan gum and sodium citrate)
|Add Syntran PC 5620 to covered batch tank. With constant agitation, slowly add Covarine dispersion with constant agitation. Stir for 30 minutes and avoid aeration.
|pH-7.0-7.6; Solids-43-45%.
More Information
|Interpolymer Corporation 781-828-7120 Website: www.interpolymer.com Email: email@example.com
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text:
- Stephen Dawes describes his passion for sport in this short video about the man behind the Newcastle Outrigger Canoe Club....Tuesday 10 April 2012
- Tuesday 29 November 2011
Explore by Topic
Latest Coaching stories on ABC Newcastle NSW
Latest Coaching stories on ABC Online
- North Ballarat's long-serving VFL head coach Gerard FitzGerald has revealed he had sought an extension of his contract before finding out it would not be renewed....Tuesday 23 June 2015
- If you were sitting courtside at the Mackay Multi-Sports Stadium last night it would have looked like a scene out of the movie Space Jam. The Mackay Meteors Men's basketball side towered over the women's Whitsunday Sharks netball team, but despite the obvious height advantages, it was a close ...Thursday 16 April 2015
- Rod Laver was a master of the game of tennis in a golden age of the sport....Thursday 19 March 2015
- Bianca 'Bam Bam' Elmir is an internationally successful kickboxer, and now a rising star on the boxing scene....Wednesday 18 February 2015
- Australia's two major political parties have had ten leaders in the last ten years and again leadership speculation grips the nation this week. What does this say about us as a nation and how much of our political judgement is driven by self-interest? ...Sunday 8 February 2015


text:
Just the Facts
Basic statistics about the realities of poverty faced by Canadians
- 1 in 7 (or 4.8 million) people in Canada live in poverty.
- In Edmonton, 1 in 8 individuals are currently living in poverty.
- Poverty costs Canada as a whole between $72 billion and $84 billion annually; Ontarians pay $2,299 – $2,895 per year, while British Columbians pay over $2,100 per year.
Marginalized Groups: Members of society that are especially vulnerable to poverty including persons living with disabilities, single mothers, Aboriginals, elderly individuals, and racialized communities
- 21% of single mothers in Canada raise their children while living in poverty (7% of single fathers raise their children in poverty).
- People living with disabilities (both mental and physical) are twice as likely to live below the poverty line.
- 1 in 5 racialized families live in poverty in Canada, as opposed to 1 in 20 non-racialized families.
- Nearly 15% of elderly single individuals live in poverty.
Food Insecurity: Not having enough food to eat or having to eat lower nutritional quality food
- Residents in Nunavut spend twice as much on food as the rest of the country on average ($14,800 v. $7,300 annually).
- 1 in 8 Canadian households struggle to put food on the table.
- 62% of children living in the North are food insecure.
- 374, 698 Ontarians visited food banks in March 2014.
- 2 out of every 5 Northern households are food insecure.
International Rankings: How Canada compares to other countries on poverty-related issues
- Canada ranks 24th out of 34 Organization for Economic Co-operation and Development (OECD) countries in terms of poverty levels.
- UNICEF rated Canada 17th out of 29 wealthy countries due to the number of children living in poverty in Canada.
Health: How poverty can affect the physical and mental wellbeing of individuals
- 1 in 10 Canadians cannot afford to fill their medical prescriptions. Canada is the only industrialized country with a universal healthcare system but without a national pharmacare policy.
- A McMaster University study found a 21-year difference in life expectancy between the poorest and wealthiest residents of Hamilton, Ontario.
- Estimates place the cost of socio-economic disparities in the health system to be 20% of all healthcare spending.
- It has been estimated that $1 invested in the early years of a child's life can save up to $9 in future spending in the healthcare system.
Housing: Statistics about homelessness and precarious housing in Canada
- 3.3 million Canadian households are precariously housed (living in unaffordable, below standards, and/or overcrowded housing conditions).
- Over 200,000 people in Canada experience homelessness each year; as many as 1.3 million Canadians have experienced homelessness over the last 5 years.
- Almost 1 in every 5 households experience serious housing affordability issues (spending over 50% of their income on rent) which puts them at risk of homelessness.
- The United Nations Committee on Economic, Social and Cultural Rights has described the lack of a national housing and homelessness strategy in Canada as a "national emergency".
- Three-quarters of Yukon's population live in Whitehorse where the average price of housing increased 80% over six years.
- Estimates place the number of homeless individuals living with a disability or mental illness as high as 45% of the overall homeless population.
- In Toronto, there were 5,219 people who were homeless in 2013 (the latest available data). Roughly half of the homeless population were on wait lists for affordable housing during the same period.
- Canada Mortgage and Housing Corporation predicts that its major national housing program funding will fall from $3.04 billion (2010) to $1.68 billion by 2017 — a $1.36 billion difference.
Child Poverty: The number or percentage of people under the age of 18 living in poverty
- 546,000 children across the country live in conditions of poverty.
- 20.6% of children in British Columbia live in poverty.
- 1 in 5 Edmontonian children (under the age of 18) live in poverty, which increases to 1 in 3 children in single-parent families.
- 40% of indigenous children in Canada live in poverty.
- In 2011, 13.3% of all children in Canada (male and female) lived in poverty.


text:
State Solutions LLP: A 'New Wave' of Privatisation in Russia - The Opportunities & Risks for International Investors Business Wire LONDON -- November 7, 2013 A new wave of privatisation in Russia is set to offer foreign investors unparalleled returns if they can successfully navigate the political landscape, according to a new report released today. The extensive report, produced by State Solutions LLP and the Moscow-based Institute of Lobbying, predicts that the long-delayed privatisation programme will be jumpstarted by replacement of current 'political' Prime Minister Dmitry Medvedev by a more 'technical' figure early next year, with political decisions then taken by the Kremlin. The privatisation drive will see more than $51Bn worth of state assets put up for sale before 2016, with more than $30Bn worth of large national companies such as Rostelecom, VTB Bank, RZhD and Rosneft. The report, entitled "A New Wave of Privatisation in Russia: The Political and Economic Context and Investment Risks", says the Russian Government will welcome the involvement of international investors in privatisation deals. At the same time, it acknowledges that the nature of the Russian political and legal environment and its poor property rights protection record makes prior approval of a deal by the country's top-level political authorities a necessity, if risks are to be reduced. It identifies eight powerful figures close to the Russian Presidency with interests across key economic sectors and suggests that "the most comfortable scenario for foreign investors would involve taking part only in those deals where an attempt to purchase an asset would not infringe on the interests of the most powerful figures in Vladimir Putin's inner circle". The report comes one week after the Russian Government sold a 16% stake in state diamond miner, Alrosa, with US investors buying the bulk of shares. The report predicts that the initial wave of privatisations is likely to include shipping giant Sovcomflot, the national airline Aeroflot, the Archangelsk Trawl Fleet, Novorossiysk Commercial Sea Port, Rostelecom and Transneft. Other assets for the privatisation include over 1,500 state-owned regional companies and land plots. "The new 'wave' of the large-scale privatisation in Russia presents historic opportunities for acquiring the government assets and stakes in state-controlled companies across various industries", said Pavel Morozov, Managing Partner of State Solutions LLP. "For the investors – both foreign and domestic – who can navigate the risks, the return on investment is likely to be far higher than in comparable emerging markets", he added. "The Russo-British Chamber of Commerce is seeing a rapidly increasing level of interest in Russia, not only from UK exporters but also from those looking to invest into key sectors of the economy. Now is the time for a candid report that provides objective insights into the opportunities in Russia, and this is it - delivered by State Solutions and very readable," said Trevor Barton, Executive Director of RBCC. "Russia is different in the same way as every country is unique and its risks and rewards should be analysed and accounted for in the same way as investors do when they consider investments in other mature and developing markets", said Petr Medvedev, Head of CIS / UK Traderoute, Ernst & Young, who was part of the expert panel at the briefing. The 70-page report was prepared by experts with knowledge of earlier privatisations in Russia was released at a joint Russo-British Chamber of Commerce – State Solutions briefing in the City of London on the evening of 6 November. The full report can be accessed here: http://state-solutions.com/sites/default/files/pdf/Privatisation-ENG_view.pdf State Solutions LLP are specialists in official government relations, lobbying and public affairs consulting to support businesses in Russia and the CIS. Our expert knowledge and thorough understanding of legislative, regulatory and administrative systems in the region enable us to provide effective and practical solutions for businesses across industries. Our practitioners in London and Moscow are competent and trustworthy professionals. Our strategic and practical advice enables our clients navigate markets, safeguard investments and run effective business operations in the region. All our services are provided in strict compliance with UK, Russian and CIS legislation. This information was brought to you by Cision http://news.cision.com Contact: State Solutions LLP Alex Andreev Tel: 44 (0)20 3402 1707 email@example.com www.state-solutions.com
State Solutions LLP: A 'New Wave' of Privatisation in Russia - The Opportunities & Risks for International Investors
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text:
navy wool peacoat
designer's notes
Leave it to Dolce & Gabbana to modernize and rev up the static mens suit. This style has their signature Italian flair to spare.
color: Navy Drill virgin wool woven Notched lapel collar with 8 double breasted button front closure Four front pockets Allover unfinished hem and seam detailing Unlined Center vent Size 40 measures approximately 31'' from base of back collar to hem; may vary by size 88% Wool / 12% Polyamide; Dry Clean; Italy; style# 331044501


text:
ATLANTA — The budget is likely to be the only major legislation that passes either the Georgia House or Senate this week because lawmakers are only just getting their first look at the other chamber's bills.
The House Appropriations subcommittees meet this morning to approve their portions of the $18 billion budget, and the full committee will vote it out this afternoon. Then the House Rules Committee will meet to put it on the agenda for a floor vote Tuesday morning, according to House Majority Leader Larry O'Neal, R-Bonaire.
ATLANTA — A 25-year-old Cobb County man is dead after police say his stalled out car was rammed from behind by a suspected drunk driver.
The Atlanta Journal-Constitution reports (http://bit.ly/YlJWo2 ) that Olvin Gallo-Flores' 2004 Nissan 350 ZX stalled early Sunday morning on the I-285 westbound ramp from I-75 north in Clayton County.
The Mableton man died when a Chevrolet Express Cargo Van slammed into the back of the Nissan, according to police.
ATLANTA — The current leaders under the Gold Dome shows few signs of the outward disagreements of previous legislative sessions.
In the first generation of leaders after Republicans took the reins of power, harsh words and stalemates were common. The governor, lieutenant governor and speaker seemed to keep everyone at the Capitol on edge as they felt their way around their new power structure.
SAVANNAH, Ga. — On the night of March 3, 2008, John and Elizabeth Calvert vanished in other-worldly fashion from Hilton Head Island, never to be seen again.
If there had been a soundtrack to the moment of their disappearance, it might have been the soft sound of an air lock closing, followed immediately by the cold silence of empty space once occupied.
They were here, and then they weren't. It was if someone had airbrushed them off the landscape of their lives.
And they were, by all accounts, good lives.
Joana Estrada moved to Athens from Los Angeles as a 9-year-old. She moved to L.A. from Michoacan, Mexico, at the age of 2.
Estrada attended Clarke County schools through middle and high school, graduating from Cedar Shoals High in 2011.
I ran into an old friend in the Houston airport Tuesday evening. I was really glad to happen upon him because we were at the airport early and flights were being delayed by the storm back in Atlanta and my lovely wife, Lisa, and I had been alone for four days and were, quite frankly, talked out for the time being.
ATLANTA — State officials say two committees have been formed as part of a national search for the next president of Fort Valley State University.
The search and screening of candidates will be the responsibility of the 12-member Presidential Search and Screen Committee, whose members have been appointed by University System of Georgia Chancellor Hank Huckaby and Board of Regents Chairman Dink NeSmith.
The committee will hold its first meeting March 27.
ATLANTA — Anime fans and gamers are converging on a downtown Atlanta hotel for Momocon — an annual anime and video game convention.
The event began in 2005 with 700 visitors and organizers say more than 8,600 people visited the convention last year.
Organizers say the convention brings fans together to meet the voices and writers behind some of their favorite shows, characters and video games. The convention features more than 20 events, including costume and anime music video contests, a rave dance party and concerts.
ATLANTA — From inside the cockpit, Cal Flanigan watched Delta Air Lines grow over the decades from a Southern regional carrier to a global airline that assigned him to pilot its inaugural flights to Dubai and other cities worldwide.
Now, after 37 years, Delta's longest-serving pilot is hanging up his captain's stripes. Flanigan is turning 65, which is the mandatory retirement age for airline pilots.
ATLANTA — The Atlanta Falcons have agreed to terms with safety William Moore on a five-year contract.
Moore was a Pro Bowl alternate with Atlanta last season, when he had four interceptions and 105 tackles. He was one of the top names on the team's list of unrestricted free agents.
Moore, a second-round draft pick from Missouri in 2009, has made 38 starts in four seasons with the Falcons. He was limited by a hamstring injury to 12 games last season. He set a career high with five interceptions in 2010.
Athens, GA • Athens Banner-Herald ©2015. All Rights Reserved.


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Enjoy a relaxing few days at the beach at Hotel Rutamar. Whether you are looking to surf, try paragliding, learn Spanish, or just hang out,…+ view more Hotel Rutamar is a great place to spend some time. Located just steps from the Canoa's long and sandy beach, Rutamar offers top-quality facilities and cleanliness in a laid-back atmosphere.calle Zapallo, Canoa, Ecuador, 132251
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Paraiso Surf & Travelers Hostel is being opened its doors recently early in 2011, the Paraiso Hostel is one of the best backpacker hangouts…+ view more in Canoa, South West Coast of Ecuador.Main Street Canoa Downtown, Canoa, Ecuador, N/A
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text:
Funding via Hattha Kaksekar Limited (HKL), a partner of Save the Children
Mrs. Chhay has been a farmer since she was married. They could make about $3 a day. She now lives with her old mother who has worked in a district office as part of the internal staff, and she is able to contribute additional income monthly.
Mrs. Chhay would like to request a loan in the amount of $1000 to buy potato seed for planting as well as pay for someone to plow her fields.
Success!! The loan was 100% repaid


text:
As a Management Company Inventive Property Management provides innovative solutions that work to control the cost of management, and uses technology to improve productivity and the capabilities of the management team. Inventive Property Management works to automate numerous tasks including Accounts Receivable, Accounts Payable, Collections and Communications with customers and prospects.
In addition to Boat Slips, Inventive Property Management provides Search Engine Optimization and website creation as a service to it's clients. We have the ability to provide customized and professional websites to help customers find out about the locations we manage, as well as accept payments in an online format. We maintain Social Networking websites and have an advanced understanding of Search Engine Optimization to help improve search results for prospects.
Let us work with you on your project to improve the results you are seeing and to get a better value for your money.


text:
a57 2x Zoom Video link
Started May 17, 2012 | Discussions thread
Shop cameras & lenses ▾
Contributing Member • Posts: 560 • Gear list
a57 2x Zoom Video link
May 17, 2012
So I was traveling on the Blue Ridge Parkway in the rain and fog. I had my trusty a57 ready for anything. What I saw was definitely unexpected.
Here's a link to my youtube video of two turkeys fighting in the middle of the road.
I was using the a57 and Sony 18-250 at full zoom plus the 2x zoom on the a57 - handheld.
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Sony a77 II
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