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This is a great little movie. As somebody else wrote, the chemistry
between the leads was wonderful. In a way this shouldn't be compared
with the first Center Stage, which was more like Fame (trials and
tribulations of an ensemble at an arts school, in this case a dance
CS: Turn It Up is really a dance romance, which we haven't seen for a while (Step Up 2 wasn't very romantic). The first Center Stage was very cheesy, while this one is much lower on the cheese scale.
There's a great sweetness to the lead couple's relationship, and while they are clearly great dancers rather than experienced actors, they're very natural with each other.
Highly recommended and very satisfying (and the music is GREAT--I thought it was even better than the first Center Stage's soundtrack, which was also very good.)
*** This review may contain spoilers ***
I often find myself disregarding reviews by viewers who simply trash
the entire film but in this case, please take my advice.
As a big fan of the first film, I was excited to see this movie. I enjoyed the realistic elements of the lives of the characters of the first one, expecting the second film to be the same. It's obvious it has been modernized and made significantly more urban than the first one but I assumed there would be some similarities, wrong!
This film tells the story of a young "self taught" dancer who fails to get into the academy but falls for the new rising star. She finds herself working as a waitress come dancer at a club but eventually manages to overcome all the odds to gain the leading role in a new ballet "Just to show her sister you can make all your dreams come true"
Another reviewer claimed these characters had great chemistry. They may have had great chemistry but they certainly lacked acting ability. I can't say whether it was the cliché script or the poor acting but this movie became somewhat painful to watch. There were several moments of very typical flirtatious close ups and over the top crying. It was ultimately cheese in a TV screen.
Being an experienced dancer myself, I was particularly infuriated with the ending of this film in which Kate "A self taught Ballerina" triumphs over all other dancers to gain the lead in this new Ballet with her boyfriend. Not only is it extremely far fetched to say that she would receive this role but it is simply impossible for someone to (as she says) "Just watch ballet videos and mimic what I saw" IT JUST Doesn't HAPPEN! The mere fact she received the role over the more technical dancers is simply ludicrous, namely because they are significantly better (Which is emphasized in several shots)
Essentially this movie was more "Step Up" rather than "Center Stage". It lacked the discipline that was evident in the first one that so many dancers could relate to. If you enjoyed "Step Up" and can stand to watch poor acting in replacement of attractive people then you may enjoy this movie. For everyone else; Ignore the "Center Stage:" part and focus on the "Turn it up" because this film has no resemblance to the first one.
This movie turned out to be a nice surprise. I was a little concerned
that it would fall below par being a straight to DVD sequel, but it
held its own.
The strongest area would be the dance routines. Very entertaining, they kept making me want to get up and dance along. The characters were likable, believable and linked in nicely with the original story.
The weakest areas would probably be the under par dialog and the been there done that story line. But considering it is a sequel, there really wasn't a whole lot of new ground or directions they could go in. On saying that, the story was told strongly enough to keep you interested the whole way through.
A lovely little Saturday night in movie for all the dance crazed movie fans.
I really liked this movie. It was really cute. The actors were good,
the dance scenes were awesome. I didn't really expect much, but after
watching this it made me feel really good inside. Rachele Brooke Smith
and Kenny Wormald were great. They're really talented and they're both
hot. They have this chemistry, and I fell in love with both of them.
This movie is kinda different from the other dance movies like step-up and make it happen coz it focuses mainly on ballet dancing. I liked this better and I didn't find this movie cheesy and boring at all, so please give this movie a try and quit comparing this movie to all the other dance movies out there. (:
I can't believe how underrated this film is and how critical some have
been about this film. When I first watched it. I was hooked on every
scene. I showed this movie to so many of my friends and family that
love dance movies and just a feel good film, they all said how good
this movie was. The dancing is spectacular by the main character Kate.
She is absolutely gorgeous, sexy and really knows how to dance.
The acting ability was flawed in a couple of instances but we are talking about people who more than likely have dancing as their first love and profession and acting as an add on so please! ease up all you massively criticizing people out there. WE are only talking about a few instances here anyway not the whole film.
I like this film more than the first, I've gotta say. There will be people that will disagree but if you are looking for a light hearted feel good film to watch with plenty of dancing, give this one a go.
I was a bit skeptical about this movie since I did not know any of the actors. I like the idea of where they were heading with the plot, but for me it kinda lacked a bit on execution. There were a couple of scenes where it needed a little more acting to it that kinda left me hanging. Maybe put a little more emotion to it. Other than that there were some parts where I felt the lines could've been more, because for some reason it sounded like they were talking online. It's a good movie though that focuses on a girl's struggle to achieve her dream and all the hardships she went through in the process. It speaks real life and I have to say you won't be much disappointed watching this film.
i loved the chemistry between (the characters) Kate and Tommy. and their dance moves were HOT. the way they moved was very intimate. Rachele Smith's acting could have been better but the story line was good (could have been a bit better). i mean i was kind of disappointed that they didn't really have much of a story line including Kate's father. He seemed to be against her daughter's dream of being a ballerina but in the end she succeeded so they should have put some of her father in the end to show other young dreams out there that they shouldn't give up. PS-Kenny Wormald is HAWT!! and if u liked this movie then u should definitely watch Step Up & Honey.
*** This review may contain spoilers ***
The lead actress and the lead actor at times almost seemed like they were starring in a toothpaste commercial rather than a movie but I guess that's what you get when you put professional dancers in movie starring roles. Just because they can dance does not necessarily mean that they can act. Oh! come on people, give this film a break. I thought it was very nice and in fact nearly as good as the original. I however have to agree that the makeup used on the lead actress was a little bit too much but other than that she was fine in the role she was playing. Two things stood out to me as odd in the film, #1 was that the main actress could find parking on a New York City street 9a.m. on the morning of her audition, and the second thing was the fact that she was working 3 jobs yet still couldn't afford to get her car out of impound? That was just odd. Nevertheless, the dancing was on point. It a film about dancing so the less said about the acting and certain other flaws in the film, the better.
Before watching this movie I did look it up here at IMDb, and did notice it didn't really have great ratings. Well, so glad I went with my vibe and watched it anyway. I loved the film. About Kate (Rachele Brooke Smith), I very much enjoyed watching her in this film. I've never heard of her before, but now I know who she is. Aside overall pretty (adorable smile) and cool dancer, personally, I think she did very good in her role as Kate. Somebody commented that she looks like Ashley Simpson (dark hair, pre-op Ashley). I agree, in quite a few scenes, I thought so, too, and I couldn't help for a moment to wonder if Ashley Simpson might've been a good Kate, too. Well, actually, probably, she would've done okay with the ballet dancing scenes since I hear that Ashley Simpson used to dance ballet when she was younger. But as for the other dancing styles performed in this movie, the only other kind of Ashley dancing I'm familiar with aside her ballet is the "Ashley Ho-down" thing. So, on second thought, nope. I don't think it would've been appropriate for this film. Picturing her as Kate, no. I think they definitely chose the appropriate actress for this film. I'm glad they went with Rachele Brooke Smith. She owned the part. She owned the dance floor. I look forward to seeing her in other cool films such as this. I give her and the overall movie a "10"!
I absolutely loved this movie. I wasn't expecting much coming in. I figured it would be cheesy, but I was pleasantly surprised. Kenny Wormald is an amazing dancer & there's so much chemistry between him and Rachele Brooke Smith. I was actually hoping they dated in real life after watching it. They are also both excellent dancers so it's fun to see what they'll do next. I was a big fan of the original Center Stage and I'm an even bigger fan of this one. The nice thing about this movie is it's safe for children to watch. I let my 10 year old dancer watch it and she loved it. The original Center Stage I don't let her watch because there's too much sex, smoking, cussing & the part about anorexia. This movie has just a couple mild bad words & there's a little bit of grinding dancing but it's not bad at all. I would say it's safe for 8 and up. Just give this movie a chance. You'll be glad you did.
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Vets Needn't Apply
Iraq war vet Paul Hackett's surprise withdrawal from the race for the Dem Senate nomination to run against Ohio's Mike DeWine comes as a shock to the other vets being recruited by the Dems. According to several reports, Hackett's candidacy was propelled, in part, by Sen. Schumer's promise that he'd not have to worry about campaign funding. And then hitherto invisible Cong. Sherrod Brown pops up, and says he wants to run. So what's the reaction from the Dems? Little Miss Gun Control drops Hackett like a hot rock and works hard to cut off his funding. Why shouldn't vets believe this is just another symptom of the Democrat disease?
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The Muzi Ford Presidents' Day Sale is expected to be one of the largest sales events of the year for the Massachusetts Dealership that has been serving Boston drivers since 1932. The event will feature uniquely aggressive Ford Lease Offers as well as deep discounts on the local Ford dealer's extensive used car inventory.
The Muzi Presidents' Day Sales Event launched this week and will run through February 28th, offering consumers nearly 3 weeks to take advantage of the reduced rates and prices on new and used Ford cars and trucks. To view the offers simply click here.
Presidents' Day Sales In Massachusetts - A Longstanding Tradition
Car Dealers and Presidents' Day have been intimately connected for nearly a century. Boston, Massachusetts, car dealerships connection to the holiday dates back to the early 20th century. In the 1920's a car dealer named Alvan Fuller sold Cadillacs and Packards on Boston's Comm. Ave and recognized that the holiday, then Washington's Birthday, provided a unique opportunity for consumers to spend some free time browsing and test-driving some new and used vehicles. A tradition was born.
Presidents' Day - Savings Any Way You Spell It
Saavy Massachusetts car buyers understand that Presidents' Day and the year-end are two of the best times to purchase a vehicle at a deeply discounted price. The year-end is a great time to purchase a new vehicle because older model years are incentivized and dealers are working hard to put a few more sold units in the books. Presidents' Day, on the other hand, serves as an important kick-start to the year for both dealers and auto manufacturers.
While it may be clear that Presidents' Day is a great time to buy, it is not altogether clear how the holiday is spelled! After researching the official holiday calendar of all 50 states, Geometrx found that 17 states celebrate Presidents' Day, 5 states celebrate Presidents Day, and 4 states clebrate President's Day. It is enough to make a high school grammar teacher's head spin.
Muzi Ford Presidents' Day Sale - High Quality Vehicles Offered
It is well known in Massachusetts that Muzi Ford and Muzi Chevy have an impressive used car inventory that consists of high quality vehicles that have gone through a rigorous 117+ point inspection. Unlike vehicles offered at some other dealerhsips, MA car buyers know that a Muzi pre-owned car means quality and that a Muzi Pre-Owned vehicle will last.
In honor of the holiday, Muzi Ford is offering the brand new Ford Fusion for just $18,405, the 2014 Ford F-150 for just $28,999, a Ford Focus lease for just $99 per month or $239 per month with $0 Down and a Ford Fiesta lease for just $99 per month as well as many other new car offers. In addition, Muzi Ford has discounted many of its used cars and trucks that include numerous different makes and models.
To Learn More Contact:
Muzi Ford
557 Highland Ave
Needham, MA 02494


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Originally posted by jsobecky
Heard on the radio today that some were planning a "rolling hunger strike". They take turns, fasting for 8 hours, then someone comes and takes their place for the next 8 hours, and so on.
Troops Home Fast: Nationwide Hunger Strikes Protest Iraq War
The fasters plan to stay in front of the White House every day until August 14th, when they move the hunger strike next to President Bush's vacation ranch in Crawford, Texas.
Thousands of protestors gathered across the nation over the July 4th holiday to protest the Iraq war. Three thousand people around the world are fasting or have done so for at least one day this past week as part of a national "Troops Home Fast" to end the Iraq war. We speak with CodePink founder, Medea Benjamin. [includes rush transcript]


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Conference Registration Now Open
Conference Registration Now Open!
"Mothers as a Catalyst of Change: Inspiration from Around the World"
Conference Cost: $125
Click HERE to register
FRP Pre-conference
This is a separate registration. Register directly with FRP-BC email@example.com
Wednesday, November 25 (10:00 am - 4:00 pm)
(Simon Fraser University - Harbour Ctr, Vancouver)
- Session 1: "An Introduction to Working with Family Resource Programs" for people new to the field. Registration cost: $25.00
- Session 2: For "Seasoned Staff" - an in-service day to address a veriety of relevant and interesting topics (Free).
Provincial FRP Conference
"Mothers as a Catalyst of Change"
Provincial Family Resource Programs of BC Conference in collaboration with Hippy Canada
November 25 - 27, 2015
The BC Association of Family Resource Programs' Annual General Meeting will be held on Friday, November 27th
Key Note Speaker: Sally Armstrong "Ascent of Women"
Listen to Sally speak
Contact our office for workshop requests/suggestions
Let us know if you plan on attending - we are planning on an affordable registration fee so watch for more information to come
We Have Moved
As of Monday, February 23rd, 2014, the office of the BC Association of Family Resource Programs (FRP-BC) will be moving from Vancouver (South Granville) to Surrey (Newton).
Our physical address and mailing address are not the same.
We also have a new phone and fax number.
Physical Address:
Unit #104 - 13771, 72nd A Avenue
Surrey, BC V3W 9C6
Phone: 778-590-0045
Fax: 778-590-0441
Mailing Address:
Unit #145 - 6832 King George Blvd.
Surrey, BC V3W 4Z9
Early Years Conference 2016
Child Care Capital Funding
A priority for this intake will be the creation of spaces co-located with other family-support programs in community-based settings, including BC Early Years Centres, recreation centres and family resource programs. Applicants will be required to provide a description of the partnership and proposed benefits to local families and community.
Application Deadline: March 20, 2015
Maximum Application Amount: $500,000
FRP-BC AGM 2014 Presentations
CLICK HERE to go to News Page
Below are links to the presentations by our panel at the FRP-BC 2014 Annual General Meeting
Feedback on the draft criteria for the early years centres
At the Early Years Conference 2014 the provincial government officially announced the launch of the provincial Office for the Early Years. At this conference the government had a feedback form and FRP-BC has provided Feedback on the draft criteria for the Early Years Centres.
Early Years Centres
Officially announced last week at the Early Years Conference. The information table presented by the provincial government included a feedback form that is due this Friday (February 7th).
FRP-BC will be submitting our feedback.
Government Requests Feedback on Early Years Centres
Early Years Strategy
BC Families Agenda
Building a Sustainable Quality Early Years Strategy to Support BC Families
Early Years Strategy
The Families First Agenda
An Integrated System of Child Care Early Learning and Family Support
Through a UWLM Public Policy Grant, the BC Association of Family Resource Programs will provide leadership and support to manage a three-year ECD policy development initiative. We are committed to working with others to advance a provincial framework of Child Care, Early Learning and Family Support.
FRP-BC Signs MoU with the Ministry of Education
Memorandum of Understanding (MoU) with the Ministry of Education <click here>
Presentation about the MOU with MinEd
Presentation delivered at the September 19 First Call Roundtable Meeting <Click Here>
Protect Vulnerable Families
Common Sense Changes Encourage Work, Protect Vulnerable Families - BC Government Newsroom
MCFD Operational & Strategic Directional Plan
Download MCFD's Operational & Strategic Directional Plan
MCFD Operational & Strategic Directional Plan (2012-2015)
Letter to Deputy Minister Stephen Brown
FRP-BC submts letter to Deputy Minister Stephen Brown in response to the MCFD Service Plan.
FRP-BC Response Letter to MCFD Service Plan
Early Years Literature Review
Developed in partnership between MCFD and FRP-BC. The purpose of this review is to provide an overview of early years program service delivery in BC and examine the integration of early years programs and services in other jurisdictions. The report examines the following research question: Based on experiences described in other jurisdictions, what are the key enabling elements for promoting and maintaining successful integration of early years programs and services?
Click here to read the Literature Review


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Europe inundated with cheap, synthetic drugs
Hard drugs, such as heroin and cocaine, continue to be a problem for Europe. But the continent is also inundated with cheap, synthetic drugs that contain unknown substances and pose a serious health hazard.Cheap and easily accessible synthetic drugs are flooding Europe's illegal drug market. This is according to a report of Europol and the European Monitoring Center for Drugs and Drug Addiction. The study was unveiled in Brussels. The reason these substances are so prevalent is that they're produced in Europe, close to the consumers, in so-called mobile production units that can be easily installed at the back of a truck. But hard drugs, such as heroin, also remain a problem for Europe. However, unlike synthetic drugs, they don't come from the continent. Afghanistan is the main supplier of heroin. According to the UN, war and insecurity have contributed to increased opium cultivation in the country. Last year, it rose 18 percent compared to the previous year. Like synthetic substances, heroin and other hard drugs are increasingly available online. Transporting drugs also takes place away from the view of police officers. More and more often, it happens through legal options, such as postal services. Fighting the illegal drug business is important not only for its own sake, but also because it goes hand in hand with other kinds of organized crime. For example, the revenue from drug dealing is frequently used to finance a wide range of illegal activities.


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Latest Weather Blog
Content Tagged As dolphins
Tagged News
Dolphins rally, beat Jets 16-13 on late field goal
December 2, 2014 5:42 AMEAST RUTHERFORD, N.J. - The Miami Dolphins kept their playoff hopes intact by rallying for a 16-13 victory over the New York Jets on Monday night when Caleb Sturgis made a 26-yard field goal with 1:57 remaining. Miami (7-5) rallied in an old-fashioned - some might say dull - slugfest... more »
Tannehill, former Tiger Landry lead Dolphins over Bills
November 14, 2014 6:10 AMMIAMI GARDENS, FL - Ryan Tannehill shook off five sacks and a third-quarter deficit, throwing for two late touchdowns to help the Miami Dolphins break a streak of three consecutive losses to Buffalo with a 22-9 win Thursday. Tannehill went 26 for 34 for 240 yards and threw touchdown... more »
Dallas, Detroit, Miami to play NFL London in 2014
October 24, 2013 9:10 AMLONDON- The Dallas Cowboys, Detroit Lions and Miami Dolphins will travel to London next year to take part in the NFL International Series. The NFL had announced earlier this month that it would play three games at Wembley Stadium in 2014, with the Jaguars, Falcons and Raiders as the designated... more »
Saints head to 4th Quarter leading by 25
September 30, 2013 10:04 PMNEW ORLEANS - The Saints kept racking up gaudy offensive numbers in the second half, as Drew Brees tied his own NFL record with 300 or more passing yards in a game for the ninth straight regular season game. Brees is currently 23-for-31 for 337 yards passing and four... more »
Different half, same results - Saints lead 35-10
September 30, 2013 9:39 PMNEW ORLEANS - The Saints opened up the second half with the same offense that opened up their 11-point halftime lead in the first half. Drew Brees hit tight end Benjamin Watson for a four-yard touchdown score and then to Jimmy Graham for a 43-yard touchdown grab to extend... more »
Saints take advantage of Dolphins turnovers, lead 21-10(Half)
September 30, 2013 9:07 PMNEW ORLEANS -The Saints' defense has come up with two turnovers in the game - a fumble and an interception of Miami's quarterback Ryan Tannehill. Drew Brees and the offense took over at the Miami 23 yard line after a Jabari Greer interception. Brees converted the opportunity into... more »
Jimmy Graham skies for Saints second score
September 30, 2013 8:37 PMNEW ORLEANS - The Saints put a little more distance between them and the Dolphins with a 27-yard touchdown toss from Drew Brees to Jimmy Graham. Graham, who was double-covered on the play, jumped over Dolphin defenders to reel in the jump ball in the end zone. New... more »
Saints ahead 7-3 at end of 1st Quarter
September 30, 2013 8:22 PMNEW ORLEANS -The first quarter in front of a Monday Night Football audience was dominated by quarterbacks. Miami's Ryan Tannehill went 3-for-4 for 21 passing yards in leading the Dolphins down the field for a field goal; New Orlean's Drew Brees completed eight of his 10 passes in the... more »
Saints grab quick lead, 7-0
September 30, 2013 7:50 PMNEW ORLEANS - The Saints had no trouble engineering a score on their first drive of the game, a six-play, 82-yard drive capped by a five-yard touchdown scamper by Darren Sproles. On his 18-yard completion to Kenny Stills during the drive, Drew Brees passed the 47,000 career passing yards... more »
Saints take on Dolphins in Monday night battle of unbeatens
September 30, 2013 7:40 PMNEW ORLEANS - The Saints will meet with the Miami Dolphins on Monday Night Football in a battle of 3-0 teams. New Orleans comes into tonight's game 10-2 with head coach Sean Payton and quarterback Drew Brees on Monday night games. Miami's quarterback Ryan Tannehill is the NFL's... more »
Appeal of Houston's Smith denied
August 23, 2013 5:45 PMHOUSTON - Houston coach Gary Kubiak says the NFL has upheld defensive end Antonio Smith's three-game suspension. Smith was suspended Wednesday for the last two preseason games and Houston's season opener for hitting Miami guard Richie Incognito with the Dolphins player's helmet. Smith appealed the suspension, but his appeal was... more »
Undefeated '72 team honored at White House
August 20, 2013 10:43 AMWASHINGTON - It took a long time but the unbeaten 1972 Miami Dolphins are finally being honored with a White House celebration. The salute is taking place today as President Barack Obama will host former team members and their then-coach, Hall of Famer Don Shula, at a White House... more »
More dolphins turn up stranded in Texas
June 12, 2012 9:24 AMGALVESTON, Texas - More than 120 dolphins have turned up stranded in Texas since last fall and researchers are trying to figure out why. Experts are looking at the 2010 BP oil spill in the Gulf of Mexico. They're also looking at an algae bloom or other possible... more »
Dolphins from oiled bay show health problems
March 23, 2012 2:16 PMNEW ORLEANS - Scientists say 32 dolphins taken from Louisiana's Barataria Bay were in overall poor health, though they say their studies don't yet definitely tie the illnesses to the 2010 Gulf oil spill. Lori Schwacke of the National Oceanic and Atmospheric Administration said Friday that the dolphins - caught... more »
Some dispute new Gulf of Mexico study
April 18, 2011 5:40 PMBATON ROUGE - More than three dozen scientists say the Gulf of Mexico is near pre-BP spill health level, but also admit that it may take many years to determine the spill's overall impact to fish and wildlife. The scientists gave the Gulf a 68 out of 100 score... more »
8 months after spill, oil found on dead dolphin
April 7, 2011 3:35 PMNEW ORLEANS - The National Oceanic and Atmospheric Administration says that eight months after the Deepwater Horizon oil well was capped, dolphins are washing ashore in east Louisiana with some oil from that spilled on their bodies. Spokeswoman Kim Amendola says the dolphins had spots of weathered oil. ... more »
Spill damage trawl accidentally drowns dolphins
April 1, 2011 4:14 PMNEW ORLEANS - The National Oceanic and Atmospheric Administration says federal scientists catching fish to test for possible damage from last year's Gulf of Mexico oil spill accidentally drowned three dolphins. Spokeswoman Connie Barclay says the pantropical spotted dolphins were caught Wednesday from a trawl off the research ship... more »
Spill damage trawl accidentally drowns dolphins
April 1, 2011 2:28 PMNEW ORLEANS - The National Oceanic and Atmospheric Administration says federal scientists trawling for fish to test for possible damage from last year's Gulf of Mexico oil spill accidentally caught and drowned three dolphins. Spokeswoman Connie Barclay says the pantropical spotted dolphins were caught Wednesday by scientists on the... more »
More dead dolphins found along Gulf Coast
February 25, 2011 2:44 PMNEW ORLEANS- The National Oceanic and Atmospheric Administration says the number of dead dolphins found since Jan. 1 in the area affected by last year's oil spill is now 67, with 35 of them premature or newborn calves. NOAA regional spokeswoman Kim Amendola says five dead calves were reported... more »


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Nationals' proposed move to Osceola County hits $98 million snag
Osceola commission balks at price tag but will reconsider Aug. 19
11:11 AM, Jul. 16, 2013
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Nationals' proposed move to Osceola County hits $98 million snag
Washington Nationals principal owner Mark Lerner pitched a plan to Osceola County on Monday to move his team?s spring training operations from Viera to Kissimmee.
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"One-woman creative tsunami Rachael Rice—musician, artist, photographer, entrepreneur, Web designer, marketing maven, and creativity coach—roared into town from Vermont last year on the arm of returning old-school PDX folk rocker Dan Haley, quickly making Portland's music community wonder how it got along without her all these years. Tonight's Rice-led tribute to Joni Mitchell—easily short-listed for Greatest Singer-Songwriter Ever, and no multidisciplinary slouch herself—follows a successful earlier, all-female tribute to Mitchell's fellow Canuck Neil Young."
"Sweetheart of the Alt-Country Rodeo...one seriously bad-ass vocalist"


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Keep your paper towels securely on your table or countertops with the euro paper towel holder. Constructed entirely of metal for added durability. Matches well with a wide variety of kitchen styles and decor. Use it at your next family picnic or while camping to keep the paper towels neat and within reach.
Material: Metal
Metal Finish: Nickel
Finish: Satin
Mount Type: Free Standing
Care and Cleaning: Wipe Clean with a Damp Cloth
Dimensions: 12.500H x 5.500W x 5.500D
Weight: 1.285
other Info.
- Online Item #: 13856426
- Store Item Number (DPCI): 200-10-0358
- Imported


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10 Steps to Pick the Right Doctor
Whether you need a primary care doctor or a specialist, these 10 steps will ensure you find the right doctor for you. View Slideshow
Dr. Burdette's Experience
- Plastic Surgery
Board Certifications
- Plastic Surgery
- Adjacent Tissue Transfer
- Breast Reconstruction
- Breast Reduction
- Dressing and-or Debridement of Wound, Infection, or Burn (incl. Negative Pressure Wound Therapy)
- Excision of Benign Skin Lesion
- Excision of Malignant Skin Lesion
- Eyelid Reconstruction Surgery
- Eyelid Surgery
- Skin and Tissue Reduction
- Skin Excision for Hidradenitis
- Skin Grafts
- Wound Repair
- Benign Skin Lesion
- Gynecomastia
- Hidradenitis
- Second-Degree Burns
- Skin Cancer
- Third-Degree Burns
Background Check for Dr. Burdette
Malpractice Claims not available
- Healthgrades does not collect malpractice information for New Hampshire.
- No sanctions history found for the years that Healthgrades collects data.
0 Board Actions
- No board actions found for the years that Healthgrades collects data.
Awards & Recognitions
Education & Training
Languages Spoken by Dr. Burdette & Staff
- English


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Meatball Recipe - The Hot Plate
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Ever wonder how to make your very own meatballs at home? Meatballs are a versatile and delicious treat that make so many meals more delicious. Remember that you can you substitute any combination of meat you'd like!
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Chaos of parenting!
How do u handle the chaos of prenting? Do you have any tips or techniques of handling it all? So???
Routines and firm boundaries for all involved. I hate being late to things so we always leave early. Now that she is in school we have new responsibilities which she likes to try to get out of.
Lists, calendars, a lot of firm boundaries, and enforcement of them all helps. Also tell yourself, "This too shall pass" when things are tough. It always does pass.


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2 Products Found
TEMPUR-Cloud Elite Mattress
The TEMPUR-Cloud® Elite mattress by Tempur-Pedic® steps up to a thicker, even softer TEMPUR® comfort layer and more pressure relief.
Price is for MATTRESS ONLY. Bed set and foundation in images are sold separately.$2,599.00 - $5,198.00
Sealy Posturepedic Hybrid Kingsthorne Plush Mattress
A Sealy Posturepedic Hybrid Mattress Kingsthorne Plush delivers the perfect combination of comfort and support with a half foam and half springs design. Reduce tossing and turning with gel memory foam, which cradles and supports you as you sleep.
Price is for MATTRESS ONLY. Bed set and foundation in images are sold separately.$2,998.00


text:
You must earn 10,000 points to post other members' whiteboard
Congratulations on having the dedication to post for 1,500+ consecutive days! Good Luck on reaching your next goals! Warren
Congratulations on hitting 1500 consecutive days.
Thanks for posting on the BEST TOPIC on GasBuddy. ABandito X topic.
Congratulations on having the perseverance to post for 1,300 consecutive days! Good Luck on reaching your next goals!! Warren :)
have a happy new year
May your hearts be filled with peace and faith in God. May your days of doubt be replaced with days of hope and cheer. May you and your family get nurtured with lots of love! Merry Christmas and a Happy New Year 2015 to you and to your loved ones! Robert
Thanksgiving is the appointed time
for focusing on the good in our lives.
In each of our days,
we can find small blessings,
but too often we overlook them,
choosing instead to spend our time
paying attention to problems.
We give our energy
to those who cause us trouble
instead of those who bring peace.
Starting now,
let's be on the lookout
for the bits of pleasure in each hour,
and appreciate the people who
bring love and light to everyone
who is blessed to know them.
You are one of those people.
On Thanksgiving,
I'm thankful for you.
Happy Thanksgiving!
Congratulations on having the determination to post for 1,200 consecutive days! Hope that you are having a memorable weekend! Warren
keep up the good work
Hey Good Buddy, Notice you have reach 1100 Days Mark Posting, Keep up the good work, Your Gas Buddy Here.


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I too own MMT and bought it at 70 cents, I think Chen Lin recommended it, it's in Nigeria so it does have some risk, do your own dd.
It's better than Habanero for sure, the IR guy called me so many times I have lost count. But the latest drilling result does give them some hope.


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text:
Re: Signs Your Computer is Hacked or Owned
From: Joe Fitzsimons (firstname.lastname@example.com)
Date: 02/04/03
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From: "Joe Fitzsimons" <firstname.lastname@example.com> Date: Tue, 4 Feb 2003 17:12:52 -0000
I was going to answer them all, but I got bored. And before you say it, I
know some are overly simplistic.
> 1. Hackers disable your Daylight Savings Time
Or you set it up wrong, or you battery ran out, or ...
> 2. The clock on the desktop can be one hour behind or one hour ahead on
> occasion.
see above
> 3. Your Network Places Icon on the desktop disappears.
This means that you have removed client for microsoft networks, not that you
have been hacked
> 4. If using a Windows platform, when you start your computer, your
> original screen will pop up, but since the hackers need to boot into
> their Server(s), the system will quickly re-boot and the original screen
> will appear twice instead of only once. Your system may re-boot twice
> instead of once when loading Windows OEM versions.
No, those would be your dos drivers loading up.
> 5. If your computer system occasionally re-boots on it's own, again,
> the hacker may need to update their Hosts or Servers to make the
> computer system function properly.
Or you broke windows ... again
> 6. If you play Yahoo Games, you may find yourself being kicked out of
> the board your playing in. What is worse is if your winning a game and
> your the host of the board, the hacker may kick you out and not let you
> back in. When a computer system is hacker proof, you will rarely get
> booted out of a Yahoo Game. When the computer was hacker proof I went
> back to playing games and haven't been booted out of a game, yet.
You sure your not getting kick-banned by an admin?
> 7. A browser/email application you install to filter out or kill file
> certain individuals on the internet will not work for a long time. When
> your computer system is hacked, you aren't able to filter out people in
> your browser or email application for more then 1-2 days. A number of
> computer owners who's system was hacked have advised me they had the
> same problem. Because hackers are using your illegally installed Hosts
> and Servers for posting to the internet, this is why you can't filter or
> kill file them. This information was very apparent to myself and other
> ferret owners who's computer was hacked.
I won't even try to answer that one.
> 8. When you begin to see Usenet remarks made on behalf of your personal
> life which is private information.
That doesn't happen to most people :-)
> 9. Some of your personal files are modified years before they were
> created, HA-HA! Have seen a number of personal files modified 7-8 years
> before they were even created.
I think you may have set your clock wrong, or maybe your laptop ran out of
batteries (it needs them to keep the clock running even when its off)
> 10. You find a number of files hidden/readable only. Hackers seem to
> make their files hidden/readable only.
Most versions of windows hide system files by default
> 11. When you find a number of added information in your boot.ini file
> which relate to a Virtual Private Network . These can be either
> software, hardware or device driver oriented.
Are you insane?
> 12. Under Search for Files and Folders, you do a search on any file
> modified in the past month and you will see files which just don't need
> to be modified or which you don't even recognize. For the newbie, you
> want to focus on the files you don't recognize. Unless your a skilled
> professional, you won't realize which files need to be present or
> modified. To perform the above you will need to see all Hidden Files
> and Folders.
Autoupdate ???
> 13. Select Start, Settings, Control Panel, Network, and if you see one
> AOL adapter and have never used AOL. Two AOL adapters, two TCP/IP, two
> Dial-Up adapters, one or two Virtual Private Network adapters your
> computer could be hacked/owned. A Virtual Private Network is widely
> used by malicious hackers because it can host up to 254 users. "This
> applies to the average internet user who has one modem, one ISP and
> isn't running any FTP, HTTP, NNTP, PROXY, SMTP, SOCKS, SQL, SQUID
> SERVER." My skills working with VPNs is almost zero. One victim
> actually had two VPNs set-up and they were only using a modem to connect
> to the internet.
There will always be one TCP/IP for every adapter it is bound to. If VPN
supported adapters
are installed (which does not mean you have been hacked) then there will be
two of each of
the supported adapters. ie. Dialup Adapter/ Dialup adapter with VPN support,
> 14. Select Start, Run, type regedit, select File, Export Registry File,
> in the box type say 4-12-02.txt and select save. Then open this file
> with a text editor or word document and you might be shocked to find
> what really is installed on your computer system. Check the bottom of
> this file, hackers love to install a bunch of applications, Hosts and
> Servers files here.
> 15. You have to turn your computer off by the power supply on a some
> what's regular basis.
Defrag you hard drive
> 16. Installing a Network Interface Card will cause problems until the
> hackers configure this device into their Servers or Virtual Private
> Network they setup on your computer.
Or until you bind TCP/IP to it .
> 17. You find your cd-rom drive opens and closes without your
> permission.
> 18. You could hear an annoying beep coming from your system speakers.
> 19. Your windows screen goes horizontal or vertical.
> 20. The screen saver picture changes without your permission.
> 21. On occasion your mouse is out of your control or has an imagination
> of it's own. This could also be caused by a corrupt mouse driver.
> 22. All of a sudden, your speakers decide to play you some music.
> 23. Installing a hardware/software firewall for the first time can
> cause a number of different problems for you to set-up and configure.
> Considering you didn't have these installed from the beginning of your
> computer going on the internet.
> 24. Your firewall logs show alerts at 12:00 then 11:22 then 12:16 and
> back to 11:59.
> 25. If using a dial-up/cable/dsl connection you see a number of pings,
> port 0 to your computer. The reason for these pings is so the hackers
> can see if your computer is active/alive. A system needs to be online
> for the hackers to access these Hosts and Servers. What the hackers
> actually do is port scan the Internet Service Provider Block of
> addresses and find your computer either with file sharing enabled or a
> Backdoor/Trojan.
> 26. If someone is port scanning your system you will see in your
> firewall logs the port assignment isn't in any type of order. You might
> see a probe at port 1,10,9,8,6,12 etc.
if they're port scanning you, its probably not because they want to be your
friend, regardless of the order
> 27. When you find you have to set Zone Alarm firewall on medium instead
> of high settings.
Thats the default
> 28. Once you can view all Files and Folders search for files named
> spool*.*.
> 29. You may find another installed version of your software firewall
> application on your hard drive. You would need to Show all Hidden Files
> and Folders under your Settings, Control Panel, Folder Option and View,
> if using a Windows Platform.
I think its more likely you messed up a previous installation
> 30. When you see too many FTP - port 21, HTTP - port 80, NNTP - port
> 119, Pings - port 0, Proxy - port 80,8080,3128 and SMTP - port 25, port
> probes. Your computer is probably running and illegal, "ftp", "mail and
> news", "proxy", or "web server" which hackers are attempting to access
> for their own personal use.
Do you know how big IIS is? or Win32 Apache? I doubt most people have the
bandwidth to have this downloaded onto their machine in a reasonable time.
> 31. If you don't see your computer node/source IP address on a
> "consistent basis" to the right side of your software firewall log, your
> system is hacked. The hackers are tunneling via your system to attack
> other Networks and Systems so their identity can't be traced.
The firewall log file will depend on the firewall.
> 32. When you perform a traceroute on an IP address and you lose your
> node/source IP address, ISP routers IP. Or when you don't see your node
> IP address at all.
Tracert/ traceroute don't show your ip anyway. They show the first hop ip
first, then the second hop, etc.
They do this by setting the ttl (time to live) on packets to increasing
- Next message: m0f0: "Re: gateway"
- Previous message: Curtis Anderson: "Re: How to Secure Your Browsers from Malicous Hackers"
- In reply to: Snailmail: "Signs Your Computer is Hacked or Owned"
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- Reply: Curtis Anderson: "Re: Signs Your Computer is Hacked or Owned"
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Relevant Pages


text:
Page 1
2010; Vol.29 Issue 1
Chinese Journal of Cancer
Colorectal cancer is one of the most common human
malignancies in North America and Europe, and the main cause
of cancerrelated death. 1 In China, its incidence is increasing year
by year. Like other tumors, the occurrence and development of
multigene changes. The malignant behavior of tumor cells
depends on three characteristics: uncontrolled growth, local
infiltration and metastasis, all of which are dependent on decline
and even loss of functions of the adhesive system, in which cell
adhesive molecules are involved and play an important role. 2
transmembrane glycoproteins
between cells, which plays an important role in embryonic
development, morphogenesis, epithelial polarity and maintenance
of the integrity. and it is an important tumor suppressor gene as
well. 3,4 In this study, we used immunocytochemistry, RTPCR and
methylationspecific PCR to explore the function and clinical
multistageprocess involving
methylation levels in human colon cancer cell lines at the
molecular and protein levels.
of Ecadherinexpressionand itspromoter
Human colon cancer cell line (HT29) was supplied by Central
Laboratory of 2nd Xiangya Hospital, Central South University,
which is taken from ATCC. 5Aza2'deoxycytidine (5AzaCdR),
hydroquinone, sodium bisulfite were purchased from Sigma;
monoclonal concentrated antibody against Ecadherin (ZM0092),
and twostep kit(PV9000)
ZhongshanInc.; SVtotal RNA
transcription system, Wizard Genomic DNA purification kit,
Wizard DNA cleanup system were purchased from Promega.
reverse system,
HT29 cells were cultured with
10% fetal bovine serum, 100 u/mL penicillin and 100 u/mL
streptomycin, DMEM highglucose culture medium, placed in
37益 culture boxes with 5% CO 2 , 100% saturation humidity.
Logarithmic growth cells were produced into 1 × 10 5 /mL cell
suspension after digestion by trypsin. The suspension was added
to 15 sixwell culture plates, which were categorized into three
groups, with 5 culture plates in each group. Two groups were
Effects of 5AzaCdR on expression and methylation of
Ecadherin gene in human colon carcinoma cells
JianZhen Ren and JiRong Huo
Department of Gastroenterology, the Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, P. R. China
揖Abstract铱 Background and Objective:
Key words:
Correspondence to: JiRong Huo; Email: firstname.lastname@example.com
This paper was translated from Chinese into English by
and edited by Jing鄄 Yun Ma on 20091018.
The Chinese version of this paper is avaiable at:
Medical Translation
Grants: Natural Science Foundation of Hunan Province (No. 04JJ3107)
Received: 20090720; Accepted: 20091012
窑 Basic Research 窑
Page 2
Chinese Journal of Cancer
cultured with 1 滋 mol/L and 5 滋 mol/L 5AzaCdR in medium in the
first 24 h, then cultured in drugfree medium; the other group
Logarithmic growth cells were inoculated
into the sixwell culture plates with a preplaced 1.5 cm 伊 1.5 cm
cover slip on each well. Grouping and drug treatment were the
same as stated above. After 24 h of culture, 2 cover slips were
randomly selected from each group. They were picked out and
washed with PBS and then fixed with 4% paraformaldehyde for
30 min for slides making. The resulting slips were stained
following the instructions of immunocytochemical test kit, and
yellow or brown colored fine particles appearing on the cell
membrane as a positive signal. Five high power fields with 1000
cells were randomly selected, and the number of positive cells
was counted to determine the effect. Monoclonal antiEcadherin
antibody worked as primary antibody, and PBS instead of primary
antibody served as negative control, and normal tissue biopsies
as positive control.
culturedin mediumwithout
Cells without drug treatment and treated by 1 滋 mol/L or 5 滋 mol/L
5AzaCdR for 24 h were collected. SV Total RNA Isolation
System kit was used to extract the total RNA of these cells, and
the A260 /A280 ratio was 1.82.0 according to the absorbance value
measured by UV spectrophotometer, which verified the RNA
purity. Reverse transcription was done under the guidelines of
Reverse Transcription System kit. The resulting cDNA was used
as templates to amplify Ecadherin gene, with GAPDH as an
internalcontrol. Ecadherin
5'GGTTCAAGCTGCTGACCTTC3', the downstream primer was
product length was 630 bp; GAPDH upstream primer was
5'ACAGTCCATGCCATCACTGCC3', and downstream primer
length of266 bp(primers
BioEngineering Company).PCR
PE2400 PCR Amplifier, and the obtained PCR products run
agarose gel electrophoresis after fully mixed with loading buffer in
a ratio of 10:2.
upstream primerwas
and the resultingPCR
reactionwas with
Cells without drug treatment
but treated by 1 滋 mol/L or 5 滋 mol/L 5AzaCdR for 24 h were
collected. Wizard Genomic DNA Purification Kit was used to
extract the DNA of these cells, and the A 260 /A 280 ratio was > 1.8
spectrophotometer, which suggested the required DNA purity.
These DNA went through bisulfite modification according to
Herman . 5 and then purified by Wizard DNA Cleanup
System. The purified DNA solution served as templates for PCR
According to the sequence of Ecadherin gene (Genbank
accession No. L34545), methylationspecific PCR amplification
primers were designed following the approach described by
. 6 The methylated primer sequences were 5'GGTGA
ATTTTTAGTTAATTAGCGGTAC3' and 5'CATAACTAACCGAA
AACGCCG3'; the nonmethylated primer sequences were 5'GG
mentioned primers were used to amplify the Ecadherin promoter
region 5'CpG island methylation and nonmethylation alleles,
respectively. The resulting PCR products were 204 bp for the
methylationspecific primers, and 211 bp for the nonmethylation
specific primers.
PCR reaction was done with PE2400 Amplifier, with the
replacement of template DNA with sterile ddH2O as negative
electrophoresis after fully mixed with loading buffer in a ratio of
(all primers were synthesized by
productsrunagarose gel
SPSS13.0 statistical software was used for data analysis,
data are expressed with the mean 依 standard deviation (SD), and
comparisonbetween groupswas
variance. A value of
< 0.05 was considered significant.
analyzedby analysisof
HT29 cell morphology changed apparently after 5AzaCdR
treatment while they became spindle or polygonal, irregular and
sometimes grew into a cluster without 5AzaCdR treatment, and
after treatment for 24 h, some cells had reduced cell volume,
nuclear pyknosis, chromatinmargination,
cytoplasmic ratio, and the number of splitphase cells declined;
72 h after treatment, nucleolus disappeared in some cells
surrounded by the cell membrane, and cell shape changed from
the prism, polygon into a round or oval shape. Besides, a small
number of cell debris analogue and some dead cells appeared.
reduced nuclear
The initial number of cells was defined as 1, and the growth
curve drawing method was applied to cell counting. The growth of
HT29 cells under intervention of 5AzaCdR had a significant
difference as compared with the control group ( < 0.01); with the
increase in drug concentration, the cell growth rate showed a
slowing trend (Figure 1).
Figure 1
with 5鄄 Aza鄄 CdR
Growth curve of HT鄄 29 cells after treatment
Page 3
2010; Vol.29 Issue 1
Chinese Journal of Cancer
Compared with before intervention, Ecadherin expression
increased in cells under intervention of 5AzaCdR for 24 h,
difference being significant ( < 0.01). Ecadherin positive
expression rate increased from (21 依 7)% in 1 滋 mol/L 5AzaCdR
treated cells to(39 依 13)% in 5 滋 mol/L 5AzaCdR treated cells
(Figure 2).
Figure 2 E鄄
A袁 no treatment; B袁 1 滋 mol/L 5鄄
cadherin protein expression before and after treatment of 5鄄
Aza鄄 CdR; C袁 5 滋 mol/L 5鄄 Aza鄄 CdR.
Aza鄄 CdR in HT鄄 29 cells (SP 伊 400)
粤 月 悦
In HT29 cells without 5AzaCdR treatment, 630 bp specific
band of Ecadherin gene mRNA could not be amplified; and this
band could be detected in HT29 cells treated by 1 滋 mol/L and 5
滋 mol/L 5AzaCdR for 24 h (Figure 3).
Ecadherin gene promoter region was methylation positive in
HT29 cells not treated with 5AzaCdR; but it was negative when
treated by 1 滋 mol/L and 5 滋 mol/L 5AzaCdR for 24 h (Figure 4).
DNA methylation is an important epigenetic modification
regulating mode in mammals, which is the only natural chemical
modification of DNA in spinal animals. Studies have shown that
abnormal DNA methylation patterns occur in the process of tumor
development in a variety of human cancers. Those patterns
include increasedmethylase
genomewide methylation level, and the most common pattern,
the partially enhanced methylation level. 7 Hypermethylation in
CpG island of tumor suppressor gene promoter region, is an
important factor for gene transcription silencing. 8 It has been
found that in tumor cells, gene silencing of multiple tumor
(metastasis) suppressor was caused by CpG island methylation
in theirpromoter regions. Ecadherin
chromosome16q22.1. 9
Ecadherin molecules through a calcium ion to form dimers, two
adjacent cells were stabilized. This stability plays a role in
mediation of homogeneous adhesion and maintenance of integrity
expression level, decreased
gene in located on
two identical of
Figure 3 E鄄 cadherin mRNA expression before and after
treatment of 5鄄 Aza鄄 CdR in HT鄄
Lane 1袁 1 滋 mol/L 5鄄 Aza鄄 CdR; lane 2袁 5 滋 mol/L 5鄄 Aza鄄 CdR; lane 3袁
no treatment; lanes 4-6袁 GAPDH.
29 cells
Figure 4
colon carcinoma cells
Lane 1袁 no treatment; lane 2袁 1 滋 mol/L 5鄄
CdR; lane 4袁 control. U袁 unmethlylated; M袁 methylated; Marker袁 DNA marker.
MSP production of E鄄 cadherin expression in
Aza鄄 CdR; lane 3袁 5 滋 mol/L 5鄄 Aza鄄
Page 4
Chinese Journal of Cancer
咱员 暂
咱圆 暂
咱猿 暂
咱源 暂
咱缘 暂
咱远 暂
咱苑 暂
咱愿 暂
咱怨 暂
咱员 园 暂
咱员 员 暂
咱员 圆 暂
咱员 3暂
of tissue structure. The most important physiological function of
Ecadherin in epithelial malignant tumors is the inhibition of tumor
cell transfer after detachment. Much data have indicated that
inactivation of Ecadherin gene expression caused by methylation
plays an important part in the occurrence and development of
many tumors. In vitro experiments showed that Ecadherin could
inhibit tumor cell invasion and metastasis, so it was known as a
metastasissuppressor factor and its inactivation of tumors was
closely related to the infiltration growth and metastasis of tumor
cells. 10
Colon mucosa is a kind of glandular epithelium and the
maintenance of epithelial morphology depends on the expression
of adhesive molecules. Kinsella
the histological studies of colon carcinoma and colon adenoma
that decreased Ecadherin expression in colorectal carcinoma
was related to tumor differentiation, invasion and metastasis, as
well as Duke's staging. This study explored the expression of
Ecadherin in colon cancer cells. The results showed that with the
normal colon tissue expression of Ecadherin as a complete
expressioncontrol, expression
missingin humancolon cancer
accordancewith thedecreased
Ecadherin in colon carcinoma, suggesting that downregulated
Ecadherin expression might be an important mechanism in the
development of colon cancer.
Is the decreased or missing of Ecadherin expression in colon
cancer related with methylation? In this study, demethylation
agents(methyltransferase inhibitor, 5AzaCdR) were used for
intervention of methylation in HT29 cells, and Ecadherin
methylation was tested. The results showed that under the
intervention of 5AzaCdR, there were apparent morphologic
changes in HT29 cells in terms of reduced cell volume, nuclear
pyknosis, chromatinmargination,
number, and nucleolus disappearance in some nucleated cells.
With the increase in drug concentration, cell growth rate showed
a slowing trend. According to immunocytochemical staining after
24 h of drug intervention, Ecadherin positive rate increased from
(21 依 7)% when treated with 1 滋 mol/L 5AzaCdR to (39 依 13)%
treated with 5 滋 mol/L 5AzaCdR. RTPCR tests showed that
without 5AzaCdR treatment, HT29 cells had no Ecadherin
mRNA expressionwhile Ecadherin gene mRNA reexpression in
HT29 cells could be detected by 1 滋 mol/L and 5 滋 mol/L
5AzaCdR treatment after 24 h. MSP
Ecadherin gene methylation was positive in untreated HT29
cells, but it was negative in HT29 cells exposed to 1 滋 mol/L and
5 滋 mol/L 5AzaCdR for 24 h, which was in accordance with the
results from Nojima ., 13 Darwanto
This phenomenonsuggested
methylation might be a significant mechanism of Ecadherin gene
inactivation in colon cancer. In addition, no partial methylation
was found in this study, which might be related to primer design.
. 16 and Si . 17 reported that over methylation
. 11 and Hu . 12 found in
of Ecadherin
or missing
cells. This
reducedsplitphase cell
testsshowed that
. 14 and Garinis
. 15
of Ecadherin gene promoter caused loss of Ecadherin protein
expression in cell lines of gastric cancer, liver cancer, bladder
cancer and esophageal cancer, which could be recovered with
5AzaCdR treatment. Our study also confirmed that Ecadherin
gene promoter methylation was positive in Ecadherin expression
downregulated HT29 cells detected by MSP. It was also found
that after being treated with 5AzaCdR, Ecadherin expression
regained in these cells according to immunocytochemical staining
and RTPCR. These phenomena are in agreement with the
epigeneticmechanisms that high methylation
expression. 18
Ecadherin is a hot topic in cancer research, and its dynamic
expression, DNA methylation regulation, and their relationship
with cancer are worthy of further indepth studies. In combination
with Ecadherin expression and CpG island methylation of its
gene promoter region, it is of great significance to investigate the
relationship between the tumor and Ecadherin at protein and
molecular levels so as to reveal the mechanism of tumor
occurrence and development, and to predict the malignant degree
and prognosis of the tumors. Besides, these studies will provide
some molecular theory basis and experimental evidence for
clinical early diagnosis, detection and treatment of the tumors.
Mancini DN, Rodenhiser DI, Ainsworth PJ, et al. CpG methylation within
the 5' regulatory region of the BRCA1 gene is tumor specific and includes
a putative CREB binding site [J]. Oncogene, 1998,16(9):1161-1169.
Suske G. The Sp鄄 family of transcription factors [J]. Gene. 1999,238(2):
Momparler RL, Bovenzi V. DNA methylation and cancer
Physiol, 2000,183(2):145-154.
Nan X, Ng HH, Johnson CA, et al. Transcriptional repression by the
methyl鄄 CpG鄄 binding protein MeCP2 involves a histone deacetylase
complex [J]. Nature, 1998,393(6683):386-389.
Herman JG, Graff JR, My觟 h覿 nen S, et al. Methylation鄄
novel PCR assay for methylation status of CpG islands [J]. Proc Natl
Acad Sci U S A, 1996,93(18):9821-9826.
Tamura G, Yin J, Wang S, Fleisher AS, et al. E鄄 Cadherin gene promoter
hypermethylation in primary human gastric carcinomas [J]. J Natl Cancer
Inst, 2000,92(7):569-573.
Schmutte C, Yang AS, Nguyen TT, et al. Mechanisms for the involvement
of DNA methylation in colon carcinogenesis [J]. Cancer Res, 1996,56(10):
Broday L, Cai J, Costa M. Nickel enhances telomeric silencing in
Saccharomyces cerevisiae [J]. Mutat Res, 1999,440(2):121-130.
Halbleib JM, Nelson WJ. Cadherins in development: cell adhesion,
sorting, and tissue morphogenesis [J]. Genes Dev, 2006,20 (23):3199-
Melki JR, Vincent PC, Brown RD, et al. Hypermethylation of E鄄 cadherin in
leukemia [J]. Blood, 2000,95(10):3208-3213.
Kinsella AR, Lepts GC, Hill CL, et al. Reduced E鄄 cadherin expression
correlates with increased invasiveness in colorectal carcinoma cell lines
[J]. Clin Exp Metastasis, 1994,12(4):335-342.
Hu CM, Huo JR, Zhou SQ, et al. The expression and the significance of
e鄄 cadherin and 酌 鄄 catenin in Colorectal Carcinoma [J]. J China Med Uni,
2008,6(37):773-775. [in Chinese]
Nojima D, Nakajima K, Li LC, et al. CpG methylation of promoter region
[J]. J Cell
specific PCR: a
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Chinese Journal of Cancer
inactivates E鄄 cadherin gene in renal cell carcinoma [J]. Mol Carcinog,
Darwanto A, Kitazawa R, Maeda S, et al. MeCP2 and promoter
methylation cooperatively regulate E鄄
colorectal carcinoma [J]. Cancer Sci, 2003,94(5):442-447.
Garinis GA, Menounos PG, Spanakis NE, et al. Hypermethylation鄄
associated transcriptional silencing of E鄄 cadherin in primary sporadic
colorectal carcinomas [J]. J Pathol, 2002,198(4):442-449.
Yoshiura K, Kanai Y, Ochiai A, et al. Silencing of the E鄄
cadherin gene expression in
cadherin invasion鄄
suppressor gene by CpG methylation in human carcinomas [J]. Proc Natl
Acad Sci U S A, 1995,92(16):7416-7419.
Si HX, Tsao SW, Lam KY, et al. E鄄 cadherin expression is commonly
downregulated by CpG island hypermethylation in esophageal carcinoma
cells [J]. Cancer Lett, 2001,173(1):71-78.
Corn PG, Summers MK, Fogt F, et al. Frequent hypermethylation of the 5'
CpG island of the mitotic stress checkpoint gene Chfr in colorectal and
non鄄 small cell lung cancer [J]. Carcinogenesis, 2003,24(1):47-51.


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Breakfast on the run? Stack and wrap pancake sandwiches for a satisfying morning start.
Try slices of Canadian bacon or fully cooked ham instead of the sausage patties, if you like.
Start your day off right with these morning sandwiches. Add a piece of fruit and a glass of milk for a great breakfast.
You can make the pancakes ahead, stack them with waxed paper between each pancake, and then wrap and freeze until you need them. Pop them in the toaster to heat.
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On this week's Sports Retort, I break from the four-man weave to defend the NBA and its attempts to manage the trade of Chris Paul out of New Orleans. Plus: Early bowl predictions, the NFL upsets race comes down to the wire and much more.
For the latest sports coverage, follow @WSJSports


text: salza-at-night Blogger: http://salza-at-night.blogspot.com/ 100% pure <3 Thx for supporting <3 Blogger: http://salza-at-night.blogspot.com/ Talentscout,extensive hobby labelmanager, radio-manager/ceo @stromkraftradio and passioned promoter of innovative and great music to love Mothership : http://www.zwartkrijt.com/.. Support and expose music from upcoming talents worldwide " the Next Generation of New Hero"s" Based in the Netherlands *No blog for Dirty Dutch, Trance, Hardcore, Dubstep or edm My blog has a preference for producers. Feeling naughty? Got the skills ? Think I am definitely missing out on your stuff? ...Please make sure to drop me a line with your tracks/news, releases. Thank you*** <3 feel the music<3


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Morrison church site of free dinner on Thanksgiving
MORRISON – The fourth annual free Thanksgiving dinner will be at noon Thursday at Ebenezer Reformred Church, 309 E. Park St.
The community meal will include turkey and all the trimmings.
Meal delivery and pickup are available. Call Jane Haan at 815-772-7064 or Sharon Habben at 815-772-2082 by noon today, if possible.


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So Yeon My Daughter
Jin Se Yun
Name: 진세연 / Jin Se Yun
Profession: Actress
Birthdate: 1993-Feb-15
Height: 167cm
Weight: 43kg
Star sign: Aquarius
TV Shows
Five Fingers (SBS, 2012)
Bridal Mask (KBS2, 2012)
My Daughter The Flower (SBS, 2011)
Daughters of Bilitis Club (KBS2, 2011)
The Duo (MBC, 2011)
It's Okay, Daddy's Girl (SBS, 2010)
White: Curse of the Melody (2011)
Kim Bo Yun
Name: 김보연 / Kim Bo Yun (Kim Bo Yeon)
Profession: Actress
Birthdate: 1957-Dec-31
Birthplace: South Korea
Height: 160cm
Weight: 47kg
Blood type: O
Star sign: Capricorn
Family: Husband/actor Jun Noh Min and one son
Debut: In 1976
Education: Tusculum College, graduated as an Art Major
Hobbies: Embroidery and singing
TV Shows
Feast of the Gods (MBC, 2012)
Dangerous Woman (MBC, 2011)
Indomitable Daughters-in-Law (MBC, 2011)
New Tales of Gisaeng (SBS, 2011)
Golden Fish (MBC, 2010)
Hateful But Once Again (KBS2, 2009)
Amnok River Flows (SBS, 2008)
Love Marriage (KBS2, 2008)
Golden Era of Daughter in Law (KBS2, 2007)
Snow Flower (SBS, 2006)
Hwang Jin Yi (KBS2, 2006)
How Much Love (MBC, 2006)
Smile Again (SBS, 2006)
A Woman's Choice (KBS2, 2006)
Precious Family (KBS2, 2004)
More Beautiful Than a Flower (KBS2, 2004)
A Saint and a Witch (MBC, 2003)
Thousand Years of Love (SBS, 2003)
Sun Duk (MBC, 2003)
Ice Flower (SBS, 2002)
Couple (SBS, 2001)
Kim Yeon Joo
Name: 김연주 / Kim Yun Joo (Gim Yeon Ju)
Profession: Actress
Birthdate: 1980-Aug-30
Birthplace: South Korea
Height: 172cm
Weight: 50kg
Star sign: Virgo
TV Series
Glory Jane @ Man of Honor (KBS, 2011)
Scarlet Letter (MBC, 2010)
Daughter in Law (SBS, 2008)
Sad Love Song (MBC, 2005)
Pearl Necklace (KBS2, 2003)
Ice Flower (SBS, 2002)
Mothers and Sisters (MBC, 2000)
Kim Gab Soo
Name: 김갑수 / Kim Gab Soo (Kim Kab Soo)
Also known as: Kim Gap Su (Kim Kap Su)
Profession: Actor
Birthdate: 1957-Apr-07
Birthplace: South Korea
Height: 173cm
Weight: 64kg
Star sign: Aries
Family: One daughter
TV Shows
Just Like Today (MBC, 2011)
All My Love (MBC, 2010)
My Happy Home (MBC, 2010)
Housewife Kim Kwang Ja's Third Activities (MBC, 2010)
Sungkyunkwan Scandal (KBS2, 2010)
Secret Investigation Record (tvN, 2010)
Cinderella's Sister (KBS2, 2010)
Merchant Kim Man Deok (KBS1, 2010)
Chuno (KBS2, 2010)
Jejungwon (SBS, 2010)
Hometown Legends (KBS2, 2009)
Soul (MBC, 2009)
Partner (KBS2, 2009)
The World That They Live In (KBS2, 2008)
Tazza (SBS, 2008)
When It's At Night (MBC, 2008)
Don't Ask Me About the Past (OCN, 2008)
Dae Wang Sejong (KBS1, 2008)
The Innocent Woman (KBS2, 2007)
Get Karl! Oh Soo Jung (SBS, 2007)
Time Between Dog and Wolf (MBC, 2007)
Ground Zero (MBC, 2007)
By My Side (MBC, 2007)
When Spring Comes (KBS2, 2007)
Yeon Gae Somun (SBS, 2006)
Alone in Love (SBS, 2006)
The Invisible Man (KBS, 2006)
Wolf (MBC, 2006)
The Youth in Bare Foot (MBC, 2005)
Hometown Station (KBS, 2005)
Resurrection (KBS, 2005)
Land (SBS, 2004)
Emperor of the Sea (KBS, 2004)
The Age of Heroes (MBC, 2004)
Butterfly (나비) (MBC, 2004)
Merry Go Round (MBC, 2003)
Age of Warriors (KBS1, 2003)
Times of Purity (순수의 시대) (SBS, 2002)
Orient Theatre (KBS2, 2001)
Stepmother (새엄마) (KBS1, 2001)
Emperor Wang Gun (KBS, 2000)
House Above the Waves (파도 위의 집) (SBS, 1999)
Lee Jong Soo
Name: 이종수 / Lee Jong Soo (Lee Jong Su)
Profession: Actor
Birthdate: 1976-Oct-21
Height: 180cm
Weight: 69kg
Blood type: A
Star sign: Libra
TV Shows
King Geunchogo (KBS1, 2010)
Call of the Country (KBS2, 2010)
Everybody Cha Cha Cha (KBS1, 2009)
Fight (TVN, 2008)
Daughter in Law (SBS, 2008)
Yi San (MBC, 2007)
Kid Gang (OCN, 2007)
Yeon Gae Somun (SBS, 2006)
Next (MBC, 2005)
Han River Ballad (MBC, 2004)
Jang Gil San (SBS, 2004)
Breathless (MBC, 2003)
Good Person (MBC, 2003)
Forever Love (MBC, 2003)
Golden Pond (SBS, 2002)
Orange (SBS, 2002)
Bad Girls (SBS, 2002)
Father and Sons (SBS, 2001)
Aim for Tomorrow (MBC, 1998)
White Night 3.98 (SBS, 1998)
Forever Yours (MBC, 1998)
Love (MBC, 1998)
Oh Yun Soo
Name: 오연수 / Oh Yun Soo (Oh Yeon Soo)
Profession: Actress
Birthdate: 1971-Oct-27
Height: 165cm
Weight: 43kg
Star sign: Scorpio
Blood type: O
Education: Yeudo Elementary School, Yeudo Junior High School, Anyang Art High School, DanKook University
Debut: 1990 MBC Talent
TV Series
Gye Baek (MBC, 2011)
Bad Guy (SBS, 2010)
Dancing With the Enemy (KBS2, 2009)
The Queen Returns (KBS2, 2009)
Bittersweet Life (MBC, 2008)
The Book of Three Han (MBC, 2006)
Sad Goodbye (KBS, 2005)
Second Proposal (KBS, 2004)
Snowman (MBC, 2003)
Law of Marriage (MBC, 2001)
Woman on Top (SBS, 2000)
Love and Success (MBC, 1998)
Shoot Toward Tomorrow (MBC, 1998)
Mother's Flag (SBS, 1996)
Mangang (SBS, 1996)
War and Love (MBC, 1995)
The Man Worries Me (KBS, 1994)
Endure Sunday (KBS, 1993)
Son and Daughter (MBC, 1992)
Eyes of Dawn (MBC, 1991)
Arang and the Magistrate Episode 9 Recap by Softy
character list
Arang – A
bang wool -B
Eun Oh -E
Dol Swe – D
Joowal -J
Lord Choi – Choi
3 Bangs
E's mom – lady Seo – Seo
her reaper – MR (short for E's "mom's reaper")
Jade Emperor – Jade
Mu Young -M (his sister's name is Mu Yeon so it's really hard to hear the difference)
LSR -arang's real name
Starts from choi entering and being greeted. Choi says how this placeis old so if you are uncomfortable let me know but E says I will takecare of it so don't pay any attention to it. Choi asks why did you askto meet but E says I didn't ask you – I summoned you. they talk aboutthe grave and E asks why choi got involved and interfered with a murderinvestigation by covering up the site and destroying evidence. Choi asksdo you think the villagers don't know about that grave – they all know.he says how there was a terrible massacre at one time so it's not amurder scene, but just a mass grave. He couldn't stand by and watch thevillagers go through the pain of reliving it by having it dug up again.E: you expect me to believe that. choi says I don't want this villageshaken up and want it to be quiet. E: for who's sake do you want thisvillage to be quiet. His words anger choi
Son Eun Seo
Name: 손은서 / Son Eun Seo (Sohn Eun Suh)
Real name: 손지연 / Son Ji Yun (Sohn Ji Yeon)
Profession: Actress
Birthdate: 1986-Jun-26
Height: 170cm
Weight: 45kg
TV Shows
May Queen (MBC, 2012)
Love Rain (KBS2, 2012)
My Daughter The Flower (SBS, 2011)
Noriko Goes to Seoul (KBS2, 2011)
Myung Wol the Spy (KBS2, 2011)
Flames of Ambition (MBC, 2010)
The Queen Returns (KBS2, 2009)
Don't Ask Me About the Past (OCN, 2008)
Park Si Yeon Gives Birth to Healthy Girl
For the first time ever, Park Si Yeon greeted her baby daughter.
On September 24 around 11:30AM (KST), Park Si Yeon delivered a healthy baby weighing of 3 kilograms in Seongnam. Both the mother and newborn are healthy.
Park Si Yeon married her husband, who is older by four years, on November 19, 2011. They were able to welcome a baby girl after two years.
Her agency, Didim531 stated, "For the safety of both the mother and child, they visited a safe hospital that is ranked number one in the nation for the most experience. Both the mother and infant are healthy, and her husband and mother are quite delighted with the birth of their daughter."
Kim Do Yeon Admits to Dating Infinite's L and Woollim Responds
Back in September, dating rumors broke out that Infinite's L was dating Kim Do Yeon, an online shop owner and aspiring actress. Woollim Entertainment denied the rumors, saying they were just friends, but now Kim Do Yeon has stepped forward to say otherwise.
On November 26, Kim Do Yeon posted on her twitter a long explanation about what has happened after the dating rumors.
"I can't just sit still receiving all the harm, so I'm writing this now after holding it in. When the dating rumors came out, that agency asked me to stay be quiet for Myung Soo's sake, so I did. I thought for him, I could withstand it," said Kim Do Yeon.
Kim Do Yeon says she and INFINITE's L did date + Woollim rep admits it's true
Ulzzang Kim Do Yeon, who previously received quite a bit of backlash after the dating rumors with L, has finally spoken up to say she and the INFINITE member did indeed date, and opened up about the matter as well as warn of legal action against hate comments and actions
Kim Do Yeon tweeted today, "After the dating rumors, I did not explain myself due to Woollim"s request, but now it has come to this point because I can no longer keep silent with the amount of physical and mental damage I have received. I will be filing lawsuits against hate comments", along with an image file of the full statement she has written to express her thoughts about her situation.
Actor Hwang In Hyuk and Actress Kim Yeon Joo are Both Getting Married Soon!
Two celebrities have shared the happy news of their upcoming wedding today, and those two lucky ones getting married are Hwang In Hyuk and Kim Yeon Joo!
Hwang In Hyuk rose to stardom as an actor, but is currently practicing Korean shamanism. He will be tying the knot with Lee Seung Min, nine years his junior, in March next year. The two have known each other for a long time, but since 2010 they have been more than just friends. The couple already has a daughter born in 2011, and despite not getting married back then, they have trusted in their relationship and built their family. There have been personal issues that have caused them to postpone the wedding, but they are very determined to finally tie the knot in March and are currently trying to set the exact date.
Lee Seung Gi and His Nunas and Dongsengs
As his career continues to flourish, Lee Seung Gi's had the chance to work several beautiful and talented ladies.
And the list continues to grow with Lee Seung Gi learning to work with women of all ages from 14 to 66.
Kim Yoo Jung
As one of the youngest women that Lee Seung Gi worked with, Kim Yoo Jung shined in Lee Seung Gi's music video for Return.
Just like the title, Return was Lee Seung Gi's big come back as a singer after so many other projects, which is why Kim Yoo Jung (the most popular child actress at the time) and Lee Seung Gi working together was much anticipated.
High-octane thrills for fugitive Gong Yoo in The Suspect
Sure, it's a pretty timeworn formula to make your blockbuster action movie about a super spy who's been left to fend for himself in a strange land, but hell, I've seen the Bourne trilogy more times than I can count, so it's not like I'd say no to slick, pulse-pounding thrills. Plus, Gong Yoo. His new movie The Suspect has released posters and an official trailer as it gears up for a December premiere, and it looks like all the crazy stunt work pays off. He looks BADASS.
Kdrama Answer Me 1994 Episode 13 Recap
Answer Me 1994: Episode 13 by Drama Beans: "The 10,000 hour rule"
In 2002, we finally wind down the most boring wedding ceremony in history, as a couple of guests speculate about the Very Special Wedding Singer coming today, whom Samcheonpo introduces… as himself, ha. Everyone grumbles in disappointment.
The song is The Blue's "Feeling Only You," and Samcheonpo declares himself the Sohn Ji-chang role in this duet, with someone else filling in for Kim Min-jong's part. Ooh, I want it to be Binggeure, now a successful singer. Samcheonpo belts out the first verse, and passes the metaphorical baton over to his partner… omg, it's Kim Min-jong? The real one? Oppaaaaaa! (Hey, y'all have Garbage oppa, I have Min-jong oppa.)
"Secret" – Thoughts on Week 3
"Secret" – Thoughts on Week 3 Recap by Couch-KimChi:
Whoa, this drama has completely taken over my life. I've watched each episode several times and find myself thinking about certain scenes over and over. It's fascinating – some actions by the characters can be construed many different ways so things are left open to interpretation. Did the writer intend for that to happen? If so, he's brilliant! (I did read this screenplay won an award or something)
And the actors are all brilliant, playing characters ambiguously and leaving the audience with tiny clues to decide just who these people are. Or leaving the audience with NO clues and it's up to us to decide what the expressions on their faces mean. Is this character evil? Or is he protecting a loved one? I wasn't intending to recap this drama but I can't shut my brain down. (LOL) So let's discuss what happened this past week and you can let me know what you think.
"Secret" – Week 4 Recap
"Secret" – Week 4 Recap by Couch-Kimchi:
This drama just keeps getting better and better, the writing, the acting, the music – just everything! Each week, I wait for and kind of expect some drama cliché to work itself into the script and each week, I'm delighted that the writer has managed to avoid cliché stuff. I am literally on the edge of my seat with every episode. This drama is excellent, I highly recommend!
This week begins with Yoo Jung in the hospital and Min Hyuk sitting beside her bed, wiping the sweat from her face and telling her to wake up. It seems she was over-fatigued and not eating properly. When her eyes flutter open, he quickly shifts the tissue so she won't see him. She falls back asleep and he leaves. In the car, he says to himself that he doesn't want to see a woman die because of him and cutely snaps at his assistant, Gwang Soo (Choi Woong) that he doesn't want a reply from him.
"Empress Ki" – Recap Week 3 (Episode 5 - 6)
"Empress Ki" – Recap Week 3 (Episode 5 – 6) by Couch-Kimchi:
As I suspected, the light humorous stuff is over and we're heading into darker territory. I thoroughly enjoyed the time Ki spent with our petulant, whiny Ta Hwan but I guess it was time to move the story forward. (LOL) Speaking of, this drama moves very quickly – there is no time wasted with meaningless fluff. I hope we're able to keep that up for 50 episodes? Pray with me.
Ki wakes up in the forest to discover Ta Hwan is gone. She frantically runs around looking only to discover he's been caught in a trap and is hanging by one ankle upside-down. LMAO! He begs her to cut him down, promising that he won't run off again. These two fight all the time – it's hilarious. She ties him to her so he can't run while he continues to protest that if they return to Goryeo, they'll both die. She think the Goryeo King Wang Yoo will be able to protect them. Ummm…
"Empress Ki" – Recap Week 5 (Episode 9-10)
"Empress Ki" – Recap Week 5 (Episode 9-10) by Couch-Kimchi:
Ah, the holidays – it's when family descends on your home and interrupts your drama viewing. (LOL) Not that I don't love my family and turkey but how to explain how important it is to watch this weeks episodes of Empress Ki? I described the plot and our baby Emperor finally seeing Ki so they would allow me some time alone with my computer. At least until the pie is ready. Must have pie. *hee*
Best Fri-Sat-Sun Drama of 2013
The drama world kept our eyes glued to the screen all year round, but it's time to decide which drama stole the show in 2013.
We've divided the year's dramas into categories by timeslot – Mon/Tues, Wed/Thurs and Fri/Weekend – so be sure to check out each category and, of course, vote!
But choose wisely, because the top drama from each timeslot will advance to the final round, where the drama with the most votes from each category will compete for the title of Mwave′s Drama of the Year.


text:
Email AddressVerified
Phone Number▒▒▒▒▒▒▒▒ 89
1008 Friends
Reviewed12 Reviews
Offline IDPassport
- School
- Methodist Girls' School, Singapore Management University, Nanyang Polytechnic
- Work
- Growth Engineer (SEO), Entrepreneur
- Languages
- English, Français, 中文
- Jesslyn's Airbnb Symbol
I am a young woman who's passionate about the start-up scene, technology, traveling, running, brewing specialty coffee, and cooking.
In my free time, I enjoy having a beer with friends, or go to the cinema to catch the newest blockbuster.
My philosophy in traveling is to just soak it all in, and be open-minded to discovering new opportunities, places, and people.
I like to immerse myself in local cultures for extended lengths of time and to explore off-the-beaten-track areas in depth. I also love to shop at local grocery stores so I can do some cooking, sample different kinds of local food, and explore places mainly on foot.
I am definitely open to getting to know my hosts as friends. We can chat over a meal or have a nice drink together. :-)


text:
A place travelers can visit Puerto Plata City Center
Reviews: Puerto Plata City Center
Category: Sightseeing
Subcategory City (district, city, town)
Subcategory City (district, city, town)
Overall Rating
General description: Puerto Plata City CenterIf you are a fan of fine architecture and history visiting the Dominican Republic, than you should surely visit the towns of Puerto Plata. The province of Puerto Plata is in itself beautiful, but it's its center which has gained recognition from the visitors. The many historical buildings located around the center's vicinity all carry a history of their own and are exaples of waderful architecture. As such, it was recognised by the UNESCO World Heritage Centre as an important Historical Area.
28 Pictures: Puerto Plata City Center
Puerto Plata City Centerby Matthias in February 15
Puerto Plata City Centerby Boy in January 15
Puerto Plata City Centerby Boy in January 15
Hotels nearby
82% recommendation
Hotel :
offers from $107.58
per night
per night
3.3 km away
85% recommendation
Hotel :
offers from $145.92
per night
per night
3.5 km away
78% recommendation
Hotel :
offers from $71.37
per night
per night
5.2 km away


text:
Amazon is the big player, but there are others
Always pay yourself first
Join the NASDAQ Community today and get free, instant access to portfolios, stock ratings, real-time alerts, and more!
Embraer (
) is about to announce another larger than expected customer
order that will continue a re-rating process on the stock.
A quick review of the updates on
over the last two years, illustrates our view that this is one of
the best run companies in the world, and a leader in
Embraer is a charter member of the "Ambassador's Index".
Today, SkyWest (
), Inc. has agreed to purchase 100 new E175 dual-class regional
jet aircraft from Embraer, and another 60 conditional orders.
The potential size of this deal is $4.1 billion and this
should increase their order book backlog by 30% deliveries are
expected to begin in the second quarter of 2014 and continue
through mid-2015.
SkyWest will operate Embraer 175s under the United Express
brand. This deal was not expected to come until later in the year
and also is larger than expected.
The views and opinions expressed herein are the views and opinions of the author and do not necessarily reflect those of Nasdaq, Inc.
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We live in a world of horror, stress and strife -- can't women have their Kit Kat moment? (1:36)
Tags: jessi klein, comedy central presents, media, men/women, sex, friends, insults, weight/obesity
© 2015 Comedy Partners. All Rights Reserved. Comedy Central and all related titles, logos and characters are trademarks of comedy partners.


text:
San Diego Corporate Law, A Professional Law Corporation
Transactional Corporate Attorney for Small and Medium Business
San Diego Corporate Law is a corporate attorney service for corporate, securities, contract, and intellectual property law for small and medium businesses.
More specifically, the corporate attorney services provided by San Diego Corporate Law include the formation of business entities such as corporations, s-corps, and LLCs; assistance with financing through the sale of debt and equity securities; the provision of contract drafting and contract review services; prosecution and exploitation of trademarks, copyrights, and trade secrets; mergers and acquisitions; and a host of other legal services.
Established in 2009, San Diego Corporate Law is pleased to count among its clients businesses in the healthcare, biotechnology, multimedia production, insurance, publishing, financial services, construction, textiles, engineering, logistics, manufacturing, non-profit, and personal services industries, and other law firms.
San Diego Corporate Law believes in billing practices that are upfront and honest. When possible, the corporate attorney services provided by San Diego Corporate Law are offered on flat-fee pricing terms. However, corporate attorney services with variable or unpredictable duration are billed at an hourly rate.
For more information about a specific legal service, please visit the specific page on this website or contact San Diego Corporate Law by phone or email through the contact page, and please connect with San Diego Corporate Law using the provided social media links.


text:
Before buying music gear/software online, please read this
Posted 30 August 2006 - 06:03 AM
Zzounds.com has an affiliate program where OCR earns a commission if a sale is made when someone comes to their site from ours. They also happen to have competitive prices and fast shipping - I've ordered two Audiophile 2496s and a Roland mixer from them personally, as well as my Rode NT1a microphone.
If you can find a lower price elsewhere, they'll match it - they have a lowest price guarantee that they take pretty seriously.
Bottom line is, if you're making a large music gear or software purchase, we're asking that you consider them, and if you end up using them, be sure to visit OCR first and get to their site via ours - we wouldn't be affiliating with them if we thought it would lose you money, but if you buy something through them, it helps support OverClocked ReMix, and everybody wins.
Posted 30 August 2006 - 05:04 PM
but really,
it sounds good, and it's good to know about it.
Posted 30 August 2006 - 05:11 PM
next time...
Posted 30 August 2006 - 05:24 PM
Actually... I could use some new strings now.
I wonder if they have a minimum amount you have to spend though before OCR starts getting any kickbacks.
because really people there would still think about right though.
Posted 30 August 2006 - 05:59 PM
Posted 31 August 2006 - 03:28 AM
Actually, I'm gonna go see if they have a good mic pop filter, I think...
Posted 31 August 2006 - 05:07 AM
Yay for impulse buying... BUT, I use my Radium 61 all the time, miss having aftertouch, and vastly prefer octave switch keys on the far left, wheels toward the front. Plus those trigger pads just look FUN.
C1000S can run on 9V battery instead of Phantom, which makes it flexible.
Posted 31 August 2006 - 05:13 AM
Trigger pads FUN. I don't love the clicky knobs though.
Posted 07 September 2006 - 05:04 AM
Posted 07 September 2006 - 04:16 PM
Posted 08 September 2006 - 08:01 PM
Alright, Dave, you better be happy. I just spent $1500 at zzounds today. Thats what, like $70 for you? Sheesh.
Indeed - quite a few microphones there, yo! $70 for us, really - I'm keeping extremely close watch on every last penny that comes in via donations, ads, or affiliate programs, and everything is being used for purposes directly related to OverClocked ReMix.
Posted 08 September 2006 - 08:45 PM
Posted 08 September 2006 - 09:24 PM
DJP can see what we buy?
I can see what's purchased, but not by whom, unless they inform me they placed an order on a specific day and give further details if disambiguation from other orders is necessary, both of which in this case were provided.
Posted 08 September 2006 - 10:18 PM
Posted 09 September 2006 - 02:24 AM
NI-VERSARY Special Offer valid until September 10th.
Available to registered users of any one of the following products: KORE REAKTOR 4 or 5 GUITAR RIG 1 or 2 KONTAKT 1 or 2 And for registered users of two single NI products contained in NI KOMPLETE 3 (e.g. ABSYNTH 3 AND KOMPAKT).
Please note: If you purchase this KOMPLETE 3 NI-VERSARY Upgrade Offer as a user of REAKTOR 4/5, GUITAR RIG 1/2 or KONTAKT 1/2, KOMPLETE 3 must be activated until September 10th!
Above is the version info from the NI website on the Komplete 3 package listed in the link you posted http://www.zzounds.c...m--NINKOMPLETE2
In Doomsday's thread about this completely kick ass deal.
I'd love to buy this from zzsounds and on their website it says nothin about having to be a previous registered owner of other certain NI products to be able to purchase or use the Komplete 3 package they got for sale on that link.
Basically it boils down to this, if I buy this package off of zzsounds will I be able to use all the kick ass synths and instruments in this package even though I'm not a registered owner of any other NI instruments at the present moment?
Posted 09 September 2006 - 07:48 PM
I think the deal you got going with them is a good thing. It helps out us remixers by getting the cheapest prices, helps out the site bc of the commission, and it helps out zzsounds bc they get more customers.
Posted 23 September 2006 - 04:04 AM
i write music. i fix and build computers. talk to me for information regarding either subject.
Posted 23 September 2006 - 06:01 PM
Though in regards to software, I may still have to get it elsewhere.
Posted 23 November 2006 - 12:55 PM
Posted 30 November 2006 - 10:41 AM
Or I could have used my eyes, bur where's the fun in that?
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I think you may have hit on the real reason why a total sale of POET is sought instead of the licensing approach. In the previous CP OPEL was planning to design an OE interface and an IR sensor, each was to meet design specs for each respective vertical.
Well, that's just 2 verticals. And also, the 12 people on the POET team would be stretched across these two projects, plus any SBIRs they picked up.
Of course for shareholders this could mean several more dilutive equity finance projects and further delays while cash is raised. WE would also be going looking for new investors each time since all the usual sources would already be invested (and perhaps becoming impatient). All the while other competing technologies have the chance to mature.
Our new plan allows each vertical market leader to get exclusive rights to POET (hopefully at a hefty price) and to sic their engineers on the product they wish to develop. This could happen across 3-5 markets simultaneously. So while the licensing approach could theoretically make us much richer, it is also riskier based on the time it takes to complete.
From what Shepherd tells us, companies are dying to spend their cash on a *real* breakthrough technology, but they are reticent, having been burned in the past investing in technologies that have a very narrow scope and require 7-10 years to develop. POET is rare in that it is nearly completely developed and it has such broad applications to the point where no company in existence could hope to use it in all its potential markets.
IMO given POET's potential, the risk is very low *if* you are a big company and your mandate is to find and acquire new technologies both to use and to keep away from competitors. Therefore the risk is also very low for retail investors who hope to realize significant gains in a very short timeframe.
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