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hi all. our camp is looking for help getting our stuff to the playa! we usually rent a cargo van, but this year we thought we'd reach out to other burners, first. we can offer some kind of trade or compensation. it would just be cool to pool efforts with other burners, rather than bring out yet another ugly rental van out there.
so private message me if you'd like to either combine cargo hauling efforts, or if you'd like to negotiate some kind of exchange for space in your vehicle. be sure to mention in your message what you and your camp could use in exchange, if you're wanting to trade.
we're in the sf bay area, in the east bay, actually, but we'd be willing to work with anyone in the bay area.
thanks for reading! see you all out there!


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A fantastic Journey through the most characteristic streets of the Naples in search of the real taste of the Italian Food
The International Kitchen offers unique culinary excursions to Italy, France, Spain, Morocco & Mexico. Cook with accomplished chefs or warm grandmothers with generations of recipes in small groups while exploring the surrounding regions.
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Tuscany cooking lessons are the perfect way to immerse yourself in the passion of Italian and Tuscan cooking, having fun discovering the regional culture in the kitchen. Wine Tours and diving on the history fantastic experience for all wine lover
Tuscany cooking lessons are the perfect way to immerse yourself in the passion of Italian and Tuscan cooking, having fun discovering the regional culture in the kitchen. Wine Tours and diving on the history fantastic experience for all wine lover
Our hands-on courses have a thematic flair which includes special seasonal recipes as well as traditional Italian and Tuscan cooking. Encounter the culinary arts like never before. Attend our italian cooking classes!
Italian cooking and wine classes organized in private homes with Italians for 1 day to 1 week,to study with truly Italian people in a truly Tuscan enviroment,hence steeping in a Tuscan experience to the maximum. Enjoy the delights of Italian cuisine.
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Communications: Changing Dominant Narratives
GHC fellow Joya Taft-Dick, Communications and Youth Advocacy Officer at Together for Girls in the U.S., on the difference between speaking about and speaking for girls.
" I am extremely wary of being yet another white, Western woman campaigning on behalf of those who may be perceived as 'vulnerable' or 'voiceless.' Instead, I see strong advocacy as ensuring a platform for the marginalized to share their experiences and ideas, without attempting to speak 'for' anyone."


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I've been eating the same breakfast and lunch for nearly 6 years. Always a cucumber for breakfast and chicken breast for lunch (maybe a little rice). A freshly made cheeseburger for dinner ( No Mc D's style junk). Hey it works for George Foreman!...I'll eat a banana between lunch and dinner. Maybe a small salad late at night if I can eat. Rice vinegar instead of dressing, avoiding fat.
If I continue to eat the samething day after day, it's not a problem at all. It seems as if I am training my body to eat certain things. In the morning, I will crave the cucumber. At lunch, my body craves the chicken. Some people say it's not much but I sure feel more satisfied than if I ate a big ol fat junky burrito from a local fast food joint. Or 3 Big Macs filled with empty calories! If I eat junk, I never feel full or satisfied. My strange diet keeps me happy once the body is trained.
I love ice cream but once I'm on a roll, eating ice cream will make me sick to my stomach. So my weekend reward for eating wel all weeks seems to be less of a treat.
I find it strange that some people say it's wierd to see me eat the samething all the time. What's so strange? I see people stuff their faces with Quarter Pounders and deep fried burritos off the roachcoach day after day. Seems to me, we are all eating the samething day after day!
Weekly diet and a big plate of pasta before a ride keeps me energized enough for the rides I do! Down 22 lbs and riding hard, I must be doing something right!
Really got me the other day. Eating a banana at break. Some chainsmoking dude smoking a cigarette tells me that too many bananas aint good for me!
Breakfast- cucumber with red chili powder and garlic salt, YUMMMM!
Lunch- chicken breast, somtimes with rice. Todya was special, marinated which I don't usually do. Why wa today special? I dunno, maybe cause I marinated the chicken!


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Automatic inventory control techniques
Business Books, 1969 - Business & Economics - 156 pages
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The objectives of an inventory control system
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90 per cent amount of stock annual sales aS/Q average error average sales average stock level back-orders buyer calculated cent per annum cost of holding cost of ordering cost price cusum Delivery stock demand history discount economic order quantity effect Error 1 9 example exponential smoothing factor fi/outl fluctuations forecast sales forecasting method formula holding stock increase Inventory carrying cost inventory control system Item G lead level of service major manufacturer mean absolute deviation merchandise month moving average normal distribution number of orders occur op/oq system op/outl system order point order situation ordering cost peak Period Sales Forecast possible probability distribution produce retail safety stock sales figure Sales Forecast Error SALES HISTORY sales value seasonal pattern service function standard deviation stock controller stock holding stock-out style supplier supply techniques total cost total order tracking signal trend Trigg's method units warehouse wholesaler


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Car hits pedestrian on North Main StreetStaff Report | January 10,2013Rutland City Police are on the scene of a crash that injured a pedestrian on North Main Street in front of Tenney Brook Market.
The crash took place around 5:30 p.m. Police said a white sedan hit a pedestrian who was not immediately seen by the driver.
The driver stopped and was being interviewed by police at the scene. The unidentified pedestrian was put in an ambulance and taken to Rutland Regional Medical Center.
Police Sgt. James Tarbell said the pedestrian was alert and conscious, but would need treatment for a head laceration.
North Main Street is open to limited to traffic.MORE IN This Just InVermont State Police responded to a single vehicle crash on Interstate 91 southbound in Westminster. Full StoryAt about 6 p.m. Sunday the Bennington Police Department responded to 2 Bank St. Full Story
DANVILLE — From paved city streets to hilly dirt roads, runoff from Vermont's... Full Story
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Want to feel like a million bucks while you're vacuuming your house? Well, you're in luck!
Just Haver, VP of sales and marketing for Go Vacuum -- an online retailer of vacuum cleaners that has been around since 1996 -- has manufactured a set of 100 24-carat gold-plated vacuum cleaners, each with a price tag of $1 million.
If you think paying a million dollars for a vacuum cleaner is ridiculous, just wait 'till you hear how Haver came up with the idea for the million dollar cleaning tool. According to Gizmodo.com, Haver conceived of the idea for a million dollar, gold-plated vacuum while shuffling to his bathroom, his half-asleep eyes blinded by a golden light. (We're serious!).
Making matters worse, the expensive vacuum cleaner is being promoted with an equally ridiculous rap song that goes something like this: "Go Vacuum's $1 million dollar/is gonna make you holler/forget the other vacuums man/don't even bother/clean up your house in golden style/do you follow? Only 100 available/ they may be gone tomorrow." (YIKES!).
It took him about six months to manufacture them, but now Haver has 100 vacuum cleaners, each priced at $1 million. "The status and exclusivity of owning a vacuum like this can't be measured in dollar and cents," says Haver, whose $1 million dollar vacuum cleaners come equipped with a 10 amp motor, a 14-inch wide cleaning nozzle, and anti-marring urethane wheels.
But considering that you can pay $60 bucks for another person to clean your house, and that you can get a vacuum cleaner for as low as $21.00 on Amazon.com, Haver's million dollar dust-suckers might be a hard sell.
But what do you think? Does Haver's idea suck? What's the most you'd pay for a vacuum cleaner?
Why? Anyone? Why? Where are you throwing a party that you need this, the core of the earth? Behringer dubbed its 700-plus pound iPod dock (that little speck at the top of the humongous giant box is an iPhone) the iNuke Boom, and if there is such a device that can induce a bowel movement, I suppose this is it. At $29,999.00, the iNuke Boom is conveniently priced for you to choose between one semester of college and an unwieldy, totally impractical iPod dock that may or may not kill you and everyone you love when operated. Stay in school, kids.
The Cellairis booth had several glammed-out, sparkly iPhone cases paired with -- omigod! -- SHOES! I readily admit that I am not the target market for this particular case, nor do I imagine ever dropping benjamins on a holster for my iPhone. You'll notice that the golden case here rather violently reflected the flash from my camera, which I like to think happened because the entire idea is so blindingly stupid.
This one's a Japanese import from a company called Fujiiryoki. Apparently if you stand on this vibrating thing for long enough each day, it will shake the fat right off your posterior and belly, transforming the user into a lean, mean, tremor-prone machine. Now if you'll excuse me, I have to go put on some exercise clothes, attach some handlebars to my washing machine, and surf that baby to the six-pack of my dreams.
Finally, an air purifier that can follow me around and cleanse the stench of my farts as I walk.
You know, I was thinking about buying an iPad, but then I wondered: "Will I be able to take this thing with me into my bubble baths? If I accidentally leave my iPad outside and it starts to rain, will it come out unscathed? What if I become upset with my tablet, and throw it into the ocean -- when it washes ashore, will I still be able to play Fruit Ninja?" Turns out the answer to all of those questions was No! So I'm getting the Fujitsu Arrows tab instead. This thing doesn't look like it's coming to the U.S., but I hope it does -- my Kindle Fire didn't even survive falling into the toilet once!
For when you want to snap sexy photos of your neighbor through their window, but your neighbor lives eight blocks away. Good news, creepers-on-a-budget: Amazon has it for just $25,999.00!
You know, I always used to look at Hokusai's classic 19th century woodblock print "The Great Wave off Kanagawa" and think, "Man, you know what this iconic masterpiece of world art needs? Eerily raised texture lines and a neon pink cathode ray frame." Nailed it, Casio.
I don't know what's most revolting: The hypnotic spinning of raw meat, the period clicking of cow bone against dirty plastic, or the fact that Vince of Sham-Wow fame will almost certainly be screaming about this thing on 3AM infomercials in about two months. Bonus Arrested Development reference: "I'm Mr. Marinator!" "Well, Marinator, we'd just say Marinator."
Did you want to check your teeth for spinach in the sun visor before heading into the big party? TOO BAD, BRO, YOU'RE WATCHING HAPPY FEET!


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Rustic Village North in Chattanooga, TN
Rustic Village North features effeciency, 1 & 2 bedroom Apartments for rent in Chattanooga, TN. Large and well landscaped grounds, swimming pool, clubhouse, fireplace and full kitchens are only a few of the amenities found at Rustic Village North. Call us today!
Rustic Village North4616 Sunflower Lane, Chattanooga, TN 37416 USA
Floor Plans and Pricing
|$400 - $425
|1 Bathroom
|Contact for Sq. Ft.
Large and spacious. This unit is completely furnished with bar and stools, large balcony, blinds and appliances. Water and electric furnished
1 Bedroom
|One Bedroom
|1 Bathroom
|600 sq. ft.
This unit features, large spacious rooms, large balcony, blinds and appliances and water furnished.
2 Bedrooms
|Two Bedroom
|$650 - $660
|2 Bathrooms
|960 sq. ft.
This unit features, large spacious rooms, each bedroom has own bath, large balcony and water furnished. Ideal for sharing.
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Property Features
- Property Overview
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Rustic Village North in Chattanooga, TN
Effeciency, 1 & 2 bedroom Apartments for rent in Chattanooga, TN! Rustic Village North is ideally located in the heart of Chattanooga, walking distance to shopping, schools and many major corporations. Lighted tennis, volley and basket ball courts, a large crystal clear swimming pool with deck and more. It's all here for your enjoyment. Just minutes Hwy 58 which is the path to the Chattanooga Metro Airport. Discover the thrill, excitement and glee of living in Rustic Village Apartments. Give them a call and make this your last stop of the day.
Special Features
- Effeciency, 1 & 2 Bedroom Apartments
- Well Landscaped Grounds
- Lighted Tennis Court
- Volleyball & Basketball Courts
- Swimming Pool w/Deck
- Clubhouse w/Woodburning Fireplace
- Walking Distance to Stores and Shops
- Excellent Location to Hwy 58 near Hwy 153
- Large Balconies
- Water & Electric Included in Select Units
- Furnished available in Select Units
Community Features
- Apartment
- Club House
- Pool
- Standard
- Tennis Court
Apartment Amenities
- Electric Utilities Included
- Fireplace
- Patio or Balcony
Local Schools
- Brown Middle School
- Central High School
- Hillcrest Elementary School
We believe school data to be accurate, but do not guarantee that. Please be sure to verify where your children will attend school before making your housing decision.
Pet Policy
Pets under 15lbs, welcome with a $300.00 deposit. Call for further details.
- Pets Allowed
Contact Rustic Village North
Rustic Village North
Office Hours8 am - 5 pm Monday - Friday Closed Saturday & Sunday
Hwy 153 to Hwy 58 East. Go past 2 traffic lights, then turn left on the next road on the left (Oak Hill Rd); then turn right on the 2nd road on the right (Sunflower Lane). Go straight into Rustic Village North! Two short blocks from Bi-Lo and shopping areas.
As you search for your perfect apartment, please keep in mind that rental rates (including specials and discounts) and availability are very fluid in the apartment industry. Based on many factors, the rental rates (including specials and discounts) and availability can actually change not just daily, but hourly, if not even more quickly. While our advertisers do take steps to keep their information current, the rental rates or availability you may find here now at ForRent.com may not be the same as when you contact the communities.


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Pissing Contest XXL: Your 10 Best Stories of Hurting Yourselves While Having Sex
Good fucking god, did you guys ever bring it last week when we called for stories about your craziest sex injuries. There were tales of burns, stitches, broken bones, and concussions. Some of you fell off the bed, others fainted in the shower. Your stories were so amazing, in fact, that we couldn't limit ourselves to… »


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Total Reviews
Write a
2.0T Premium quattro
4dr SUV
(2.0L 4-cyl. Turbo AWD 8-speed Automatic)
I recently purchased the 3.2 Prestige S-Line and I can't for the life of me figure out how you're hitting the lights with your left knee unless you have the legs of a spider.
My 6' tall husband can't figure out how you'd do it either.
Perhaps you need to lower your seat.
As for the parking brake, I should certainly hope if you pull the lever the brake would engage.
That's what it's designed to do.
Never having driven a BMW I guess I don't have the issue of mistaking it for a window opener.
Free maintenance would definitely be a plus but I hope you're enjoying your Q5 as much as I am.
So you're "the type that sticks to what has worked in the past and the 2 BMW's I had were just fine"
so you an Audi. LOL!!
Anyway, I own this model and it sounds like you must have your seat pushed waaaaayyy up for you to hit the lights with your knee.
I don't even know how its possible.
I agree with you on the brake dust - I have never seen a vehicle's wheels get dirty so quickly.
And the Multi Media System - yes, I agree there too.
Its far too complicated.
Its over engineered.
I'm not sure if 3.2 Prestige and Premium have the same positions for the lights...
However, I have heard other posters mentioning hitting their left knee on the light switch.
I have alleviated by backing my seat back more.
Perhaps it is our leg length and body type or our preferred positions.
Some like to lean back others like to get closer.
I've had the 5000 mi. service and still love my Q5.
Gas mileage has been fantastic.
Another warning.
Be careful when going into automatic car wash.
Make sure you are fully aware of how to turn off the automatic wiper function....
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While Examiner did break the news of not being able to fly aircrafts back in August, Ubisoft has confirmed that players will be able to hack into helicopters and control them that way.
Today, Watch Dogs creative director Jonathan Morin was explaining how players can hack into each others game in a report, and he did talk about how one of the ways players can disrupt others is by taking control of helicopters that are searching for players.
"Having other players able to hack into your game, and come and watch you, is a unique experience. That includes those people who have tablets, who can show up and challenge you, fight against you, and do all sorts of things to control the city – like controlling the choppers that are flying around.
"When a companion challenges you, it's a contract that you'll accept or not – it won't happen if you say no. You can turn it off," Morin said.
This may be a bit of a compromise for players who were upset about not being able to fly around Chicago in aircrafts, but it won't be like being able to take a helicopter and fly it from one side of Los Santos to the other.
As most of you know by now, Watch Dogs is without a doubt a more grounded, dense game that focuses on the quality of the world all around you, not just on size. Chicago will definitely provide a lot of size and things for players to do, but it will be about how detailed everything around you is.
For all of our latest exclusives, previews, reviews and features, follow us on Twitter and like us on Facebook. Game On.
Thanks, OPM.


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Win Big
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This page has been viewed 33 times this month, and 938 times total.
Win BigWin Big (1993) Season 1 Episode 2-4- 406-805- Animaniacs Cartoon Episode Guide by Dave Koch
This page has been viewed 33 times this month, and 938 times total.
- Animaniacs Cartoon Episode Guide
- Warner Bros. Television Animation, Amblin Entertainment
- Cartoon Characters: The Brain, Pinky.
- Originally Released in 1993.
- Season: 1
- Color
- Running Time: 9:19 minutes.
Cartoon Summary:
The Brain's plan to take over the world involves using a super-conductive magnetic infindibulator to make everyone with loose change in their pockets stick to the ground. In order to get an infindibulator, he must get $99,000. He builds a large mechanical suit and goes on the game show Gyp-Parody to win the money. He answers every question correctly, but he blows the final Gyp-Parody question and loses all of his money.
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Tony's Blog
The projects that I do.
Sunday, 29 November 2015
I shall call him: Mini Me
I was at Oldham Library and Lifelong Learning Centre with Hack Oldham for the monthly 'Hack the Library' meet up.
Basically, it's a geeky get together to show the public what the Oldham Makerspace is about.
We got to use the library's Vex IQ robotic system.
And we used the Hack space's Cubify Sense 3D scanner to introduce local kids to the technology.
As the owner of a Mendel90 it seemed rude not to get a scan of myself. One of the members decided it would be a good idea to film the process:
This results in a .ply file which contains the 3D information and textures:
It can be viewed in Meshlab, and exported as a .STL file for printing:
I normally use Skeinforge to slice .STL files, but I always seem to have trouble getting it to create support material. For this print I use Slic3r which I set to use a layer height of 0.2mm. My Mendel90 has a 0.4mm extruder nozzle and I have never used such a small layer height before, but I was not disappointed:
Sunday, 15 November 2015
I have been thinking about getting a quadcopter for some time, but I didn't want to spend too much money. After doing some research, I decided upon the JJRC H12C. I ordered this from the UK via EBay for £48.29 delivered.
Being a total novice flying these, I was worried how long I could keep it in one piece. I was amazed though how easy it is to fly, after a few practice runs on the local playing field I was totally at ease controlling it.
Included in the price are: 1) The quadcopter. 2) The remote control. 3) A 750mAh battery. 4) A 1080P still/video camera.
I was very sceptical about the quality I would get from the camera, considering the total price of the package. But it completely exceeded my expectations. It is very susceptible to rapid changes in lighting, but for the money it is amazing. Here are some shots I took whilst flying around Foxdenton Park in Chadderton.
The controller allows you to remotely take a still photo or start a video at the press of a button. The videos with the camera fitted out of the box suffer from 'jello'. Wobbly lines on the picture. This is caused by the camera shaking about on its mount:
The simple fix for this is to force a small piece of foam between the camera body and the quadcopter. Doing this almost eliminates jello, as this shot with a DJI Phantom in the air at the same time shows
The remote control is not of the highest construction quality, but for the price it feels great. I bought a First Person View (FPV) kit from BangGood. This is a 720P still/video camera with a live feed to an included LCD display. Allowing you to view in real time what the camera is seeing.
As supplied, the LCD monitor does not fit to the remote control. So I designed a 3D printable clamp to allow it to fit:
This is available for download on Thingiverse.
Although I have no prior experience flying quadcopters, I cannot recommend the H12C highly enough. I've had loads of fun flying it, and even after a few rough landings it's going strong. If you want an outdoor quadcopter, seriously consider this one. It is easy to fly, spares are available and for the price it is superb!
Posted by Tony at 14:56 No comments:
Labels: jjrc h12c
Tuesday, 18 August 2015
On the range
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Just spent a couple of hours on the range at Arkansas Armoury.
A really friendly place for inexperienced shooters such as myself. I particularly enjoyed the Glock 17 and Springfield 1911.
Posted by Tony at 13:16 No comments:
Tuesday, 21 July 2015
Arcade Club
I joined Hack Oldham last week which is only 15 minutes drive from my house. After chatting to a few of the people there I found out about Arcade Club.
It's 40 minute drive away, and is a video arcade with 100+ video and pinball machines from 1979 ish onwards. There is a flat entrance fee of £10 (£5 for kids) and all games inside are free to play, with a drink and a cake are included in the price.
If you are in the north of the UK, definitely worth checking out the Arcade Club website. I dragged my kids along and exposed them to the games of my misspent youth. 'But there's no story!'. L1tt13 5h1t5.
Posted by Tony at 14:59 No comments:
Labels: arcade club
Pyro Box
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Some weeks ago I completed the 'Pyro Box' for Steve at Operation Lasertag.
It's more like a 'defend the hill' than the normal DomTube 'king of the hill' style game.
The box is assigned to one team, whilst the opposing team needs to attack the box. A digital display shows the box 'health' and a clear, 3D printed light bar is used to indicate hits.
Each opposing team hit reduces the box health by the shot power, and when it reaches zero an explosion sound is played. In addition, there is a wired output to drive a squib so a pyro can be activated. This is connected via the push terminals at the front. Internally, a radio transmitter sends a signal to a remote receiver that can also drive a pyro, allowing a safe distance between players and effects where required.
In addition, the box can be configured so that the defending team can 'repair' the box by shooting it, which adds their shot power (or half their shot power as a switched option) back to the box health.
The control panel is formed from laser cut 6mm acrylic and is mounted in an IP65 box with a carry handle.
Don't have a video of the complete unit, but here is a proof of concept run on the bench:
Posted by Tony at 14:10 No comments:
Labels: milestag
Sunday, 26 April 2015
Maker Faire UK
This year I was lucky enough to take my family to the Maker Faire UK in Newcastle. My local hackerspace (Hacman) were exhibiting there.
There were many more exhibitors than my local mini maker faire. With some big name shows:
The Humane Machine by Johnny White was a definite crowd puller. I particularly liked the way he made gears out of ice:
I was assuming he had used a prime number of cogs to mininise wear when I realised that this was an art installation and had probably not considered longevity:
There was a stand with a vac forming machine that had a long queue of people assembling their messages from letters:
A jewellery making booth allowed visitors to twist copper wire into strands and add beads to make their own gear:
A barbot dished out (none alchoholic) drinks. I need to make myself a (modified) version of this.
Pretty much something for everyone. Sewing for the girls:
And Robot Wars for the boys:
Beauty by the geeks had a popular stand where the kids could mush stuff up and find out about DIY beauty products
I got to play 1D pong with my oldest which was much more fun than I expected:
A 3D printer with a chocolate extruder brought on excited questions about modifying my printer from the wife:
A remote controlled hexapod robot:
Which shot foam darts into the audience:
This stand had a digital zoetrope with individual LCD panels for each element of the animation. Of course they could be uploaded with different images to allow the animation to be changed:
This guy had made amazing bearing runs from hand soldered copper wire. I failed to get video of this, but goodness knows how long it took to perfect:
Much to the delight of my 7 year old there was a chap doing a bubble extravaganza...
This stand had some kind of analogue audio system that sounded quite good:
My local Hackerspace (Hacman) were exhibiting. An unrepeatable shot of my proton pack with a Dalek in the background,,,,,,
Bertha made a guest appearance on this stand..making me realise I need to dig out the DVD and show it to my youngest.
Most kudos go to 'Litre of Light' who showed that a simple soda bottle filled with water could be re-purposed into a practical interior light:
And inside....
Posted by Tony at 15:31 No comments:
Labels: maker faire uk 2015
Saturday, 4 April 2015
New Toy. 50W laser cutter.
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I've had one of these in my sights for a while now. And I came into enough cash to allow me to buy one. I ordered from AliExpress rather than ebay, as the price seemed better.
It arrived last week via DHL. Well packed but delivered by Mr. Grumpy himself:
It's slightly bigger than the cheapest that can be bought with a cutting area of 400x300mm. As a 2015 model, it comes with accessories that would previously have to be purchased separately:
An air assist laser head and air pump. This helps to extinguish flames and generally blow unwanted smoke away from the laser head:
A digital control panel, thoughtfully worded in Chinese and English:
A Z adjustable cutting bed.
A honeycomb bed. This reduces the amount of heat transferred away from the underside of the work piece during cutting, and also allows the extractor fan to draw down any smoke:
In typical cheapo Chinese fashion, the honeycomb was not flat, with about an 8mm delta from corner to corner. I solved this by drilling M4 holes in the corners that were raised, and drilled a 9mm holes on the upper side of the frame to allow screw heads to pass inside the frame. I then drilled and tapped the Z bed to M4. This allows me to screw the corners onto the Z bed, forcing it to be flat.
It's also supplied with a water pump to cool the laser tube. I got a 32L box from Wilkinsons and drilled two holes in the top and filled it up with 25L of distilled water from Halfords.
Distilled water is required to stop any impurities in tap water from depositing inside the laser tube. This could cause hot spots. I also added some propylene glycol to act as an anti bio/freeze agent.
Included with the package was a rotary axis to allow the engraving of cylindrical pieces:
Most impressive is the laser tube itself, glass with a helix! Covered in cautions written in Chinese. No doubt recommending not staring into beam with remaining eye.
The software was supplied on a DVDR with a USB dongle. Not entirely sure if this is legitimate or not. However, once installed, it works as expected. There is a plugin for CorelDraw included on the disk which seems to be the most useful of the bunch, providing direct access to the laser cutter from CorelDraw.
The main issue with these budget laser cutters is the alignment of the mirrors. This image from LensDigital shows the laser beam path:
At assembly, they only seem to centre the laser tube on mirror 1. The user is expected to align everything else. I followed this video, and got everything aligned in about 40 minutes.
So with a day of tinkering behind me, I've managed to create a gear with the excellent, free Gear Generator and import a SVG file of a gear and cut it from 6mm acrylic. This has some random lines on it due to my inability to set the feed rate correctly, but still impressive:
A really nice feature of the cut is that it leaves no blemishes on the edges. A cut with a jigsaw would require treatment with a solvent to get this clean:
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A Letter from a Darker Past
Byline: Ken Kesey For The Register-Guard
Editor's note: This essay was published in The Register-Guard on Aug. 15, 1971, under the headline "A letter from the Coburg hills." On Monday, the Oregon Legislature voted to ban most open field burning in the Willamette Valley.
Last night (Aug. 2) I tossed my sleeping bag in the car and headed up McGowan Creek Road to a spot I've bagged out in now and then for the past decade, a nice place high up and solitary if you want to get away from things but not too far away. I parked on the western slope of the Coburg hills and rolled my bag out where I could lie and watch the valley twinkling miles below me, and the sliding moon, and the traditional August meteor shower whizzing through the high, clear night.
At dawn an early mist slid over the hilltop and moved casually on down toward the settlements sleeping below. In a couple of hours the mist burned off, and I watched a young hen grouse on a stump enjoying a fastidious first preening of the day, and on down the slope I could see our rivers winding like tinsel, and Fern Ridge sparkling to the southwest.
I read some of my Bible - Psalms - and had a hit of Strawberry Hill and went back to sleep. When I woke a scant hour later and sat up for another look down the slope, I saw an incredible sight:
The valley was on fire; I counted two, three, then eight or nine fields swishing into flame and smoke. But no distant fire engines could I hear; no warbling firehouse alarms ... On the freeway, the train depot and the mills, business seemed to be continuing as usual in spite of the manifold holocausts.
By midmorning the smoke was boiling from the scattered fields as though from so many great, and synchronized, funeral biers.
I watched in dumbfounded fascination: So this was what all that "Stop the Field Burning" talk was about. ...
The smoke rose into mighty murky pillars, into spectacular thunder heads all knobby and propenderous, like great yellow-brown puffed lips or punk knots swelling from an injured land, then all the separate pillars joined into one great bruise that began creeping the width and length of the valley.
No longer could you see Fern Ridge. Soon you couldn't see Coburg, or Highway 5, or the scruffy little foothills my granddad always warned me were the resthomes for rattlesnakes recuperating from their molt.
Finally it rose to the very summit where I was camped.
All the snags and berrybush 50 yards away were hazed by this creeping bruise. The young grouse stopped calling from behind her stump. …


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Curl Keeper questions
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Join Date: Aug 2011
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Wednesday, February 22, 2012 at 08:24PM
Curl Keeper's texture is almost like water. If I don't put it in really, really wet hair, my hair literally squeaks! I've found that when I use Curl Keeper with no other product, my hair gets very frizzy and fly-away when I air-dry or diffuse.
Personally, I can't use Curl Keeper by itself (I've used it successfully with Tweek on rainy days), but I'm not really sure if it does anything I really need, at this point in my hair growth (if ever). It seems to coat my hair, which would be perfect if my wet hair was in the style I want my dry hair to be. However, my hair curls and spirals
it dries, so the Curl Keeper seems to hold back my hair and change the curl pattern. I have the same problem with CJ Curls in a Bottle.
There are a couple of curl creams I love: Biotera Curl Creme and Ion Curl Shaping Creme. They both seem to be much lighter in weight than Curl Keeper, so my hair is free to shape itself. The creams moisturize and keep away frizz. I use gels all the time in the summer, and when I'm in high dew points, but in dry weather/low dew points, creams seem to soothe my hair.
You hair looks beautiful in your avatar - so keep doing whatever you're doing!
3b/c, Coarse, Low Porosity, Desert Climate
CG since August 2011/Occasionally Modified since 2013
: Wen Cleansing Conditioner/Coconut Lime Verbena, KC Come Clean, KCKT, Pure Argan Oil, Pure Coconut Oil,
Eco Natural Curling Cocktail, Desert Essence Hair Defrizzer and Heat Protector ECO gels


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Obama's LEGAL immigration reform 2015.What does it mean? Listen to video discussions by Attorney Rajiv S. Khanna on Immigration.com YouTube Channel. Subscribe to Our YouTube channel to be notified when new updates are posted.
Can my new employer transfer and extend my H1B at the same time?
Discussion in 'H Visa - Links to Important Info.' started by summerj, May 19, 2011.


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Back when EA premiered its list of upcoming App Store titles, one stood out for me: Heroes Lore III is now out on the App Store for US$1.99. This one's interesting -- it's a Korean RPG that's been translated over to the iPhone. If you've ever played any of the old 16-bit Super Nintendo RPGs like Secret of Mana, you'll know how this one works. You can level up and fight enemies in real time while using various abilities and gearing your way up through a sizable story. There are five classes to play with, and two different factions to fight for, as well as the ability to battle other players along the way.
Early reviews say the controls are a little wonky, so you might end up wrestling with the iPhone's touchscreen a bit. Some of the classes are a little unbalanced, too. Not all of them work as well as others, so you'll probably find a few favorites and stick with those. Still, it's very interesting to see EA bring a game like this to the App Store. If you're a fan of those old RPGs on the 16-bit systems, you'll probably enjoy this one. It's available for just a few bucks right now.
Apple iPhone 6s
Buy from $100 *
- Key specs
- Prices
- Discussions
- Type Smartphone
- Operating system iOS
- Screen size 4.7 inches
- Internal memory 16 GB
- Carriers (US) AT&T
- Dimensions 5.44 x 2.64 x 0.28 in
- Weight 5.04 oz
- Released 2015-09-25


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The purpose of this workshop was to share information with the Ukrainian authorities about the obligations of governments under the OECD Declaration on International Investment and Multinational Enterprises related to the OECD Guidelines for Multinational Enterprises, one of four instruments of the Declaration.
The private sector plays an important role in economic development. However to be beneficial to local populations, business must act responsibly. Part 2 of this blog focuses on how community engagement can help business achieve this, in harmony with the OECD Guidelines for Multinational Enterprises, and reinforce the link between responsible business and inclusive growth.
The private sector plays an important role in economic development. However to be beneficial to local populations, business must act responsibly. Part 1 of this blog discusses how business can do this, as laid out in the OECD Guidelines for Multinational Enterprises, and make a positive contribution to economic, environmental and social progress with a view to achieving sustainable development.
In 2014, many countries implemented the latest international guidelines for compiling FDI statistics. The new standards have resulted in significant changes in FDI statistics, including new measures of FDI at the global level.
Most businesses are good. They pay their taxes, they create employment, they abide by the laws, and they generally contribute to the societies in which they operate. But what can be done when businesses behave badly? This blog discusses the National Contact Points, the unique grievance mechanism of the OECD Guidelines for Multinational Enterprises, and how could be improved to better fulfill their potential.
In the wake of the collapse of the Rana Plaza garment factory in Bangladesh in 2013, initiatives to strengthen regulation of global supply chains in the textile and garment sector have multiplied. Tackling the issues involved requires sustained collaboration among industry, government, worker organisations and civil society. This project aims to promote such collaboration as well as the harmonisation of existing standards in the sector.
À l'occasion d'une visite historique du Premier ministre chinois, M. Li Keqiang, à l'OCDE, à Paris, la République populaire de Chine a décidé aujourd'hui de renforcer sa collaboration de longue date avec l'OCDE et de rejoindre le Centre de développement de l'Organisation.
This Global Forum is held to strengthen international dialogue on responsible business conduct and provide a platform to exchange views on how to do well while doing no harm in an effort to contribute to sustainable development and enduring social progress. The 2015 Global Forum will focus on showcasing concrete examples of action and results-oriented solutions from efforts on the ground.
This blog post John Morrison, Executive Director of the Institute for Human Rights and Business, discusses what the social responsibilities of sporting events should be and argues for greater oversight and due diligence at every stage of the mega-sporting events delivery process.
This blog post discusses how the UN Guiding Principles Reporting Framework, introduced in February 2015, help companies provide evidence of how they are conducting human rights due diligence: the process of assessing and addressing their human rights impacts, and tracking and communicating how well they do so.


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Paris Hilton is reportedly lined up to appear in a live version of Peter Pan.
The Simple Life star has impressed bosses at Disney with her movie roles and her online comedy sketches, according to New York Post gossip column PageSix.
And now they are said to be keen for Hilton to bring the fairy Tinkerbell to life in a live-action version of the story.
A source tells the website, "Paris has worked on her acting chops lately and showed some comedy prowess in her YouTube spoof of running for president. Disney suits saw it and think she may be developing some comedic-actress potential."


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Motorcyclist Injured In Monday Collision
Posted: 06/02/2008 - A motorcyclist was taken to the hospital after an accident on Ross Clark Circle.
Posted: 06/02/2008 - A motorcyclist was taken to the hospital after an accident on Ross Clark Circle.
Updated: 06/02/2008 - A Hartford mobile home was destroyed by fire Sunday night. Authorities say an electrical-short may have ignited the blaze in the home located on County Road 61.
Updated: 06/02/2008 - As officials in Dothan continue to try to find a happy medium with the animal ordinance, a neighboring city is trying to just keep them off the streets.
Posted: 06/02/2008 - The City of Dothan is asking its water customers to comply with the Stage 2 water conservation plan.
Posted: 06/02/2008 - Alabama's top election official expects a light turnout for the primary election.
Updated: 06/02/2008 - On a busy day, the Wiregrass Transit Authority has 13 buses on the roads of Houston County. Keeping them all running is becoming increasingly difficult. A majority of riders are senior citizens and those in need of healthcare.
Posted: 06/02/2008 - One man is dead and another driver injured after a car accident in Coffee County.
Posted: 06/02/2008 - A Coffee County jailer is out on bond after being indicted for sexual misconduct on Saturday
Posted: 06/02/2008 - A Dothan man remains in the hospital after being shot. Dothan Police and Fire responded to a 911 call about a person lying on the side of the road on Plant Street early Saturday morning.
Posted: 06/02/2008 - A man is behind bars after he allegedly kidnapped his estranged wife.
Updated: 06/02/2008 - The old bridge on Brannon Stand Road closed this morning at 6 am and the detour bridge is open while county workers are readying the new bridge site.
Posted: 06/02/2008 - Enterprise Police have arrested a man believed to be connected to two robberies over the weekend.
Posted: 06/02/2008 - The organization provides Seeing Eye dogs for visually impaired people in the United States and Canada, free of charge.
Updated: 06/02/2008 - A Geneva County toddler has drowned in a pool in Malvern. Officials say two-years-old Austin Lee McNeal's body was found Sunday around noon.
Updated: 06/02/2008 - With gas prices at a record-high, many residents are struggling to make ends meet.
Posted: 06/02/2008 - With summer approaching the need for blood donations in the Wiregrass is increasing.
Updated: 06/02/2008 - Asthma is the most common, serous chronic childhood disease.
Posted: 05/29/2008 - Bay County, Florida authorities arrested a woman they say robbed a taxi driver at gunpoint.
Posted: 05/29/2008 - The Alabama Senate has passed a state education budget in special session after failing to approve a budget during the regular session.
Posted: 05/29/2008 - A one time law enforcement officer here in the Wiregrass will spend the rest of his life behind bars.
Posted: 05/29/2008 - A judge described Christopher Powers as a child predator who should never again experience a day of freedom.
Posted: 05/29/2008 - The Houston County Sheriffs office recently implemented a new program to help find missing children. It's called the Child is Missing Alert.
Updated: 05/29/2008 - Enterprise High School students took center stage Thursday night.
Updated: 05/29/2008 - It's been a little more than two weeks since 26 horses were taken from a Jackson County man, after he was allegedly starving them to death.
Updated: 05/29/2008 - The Dothan Regional Airport will be the first to welcome the First Lady's arrival to the Wiregrass.


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Are you Claudia Mattern?Claim your profile
Publications (32)117.83 Total impact
Article: Analytical challenges for measuring steroid responses to stress, neurodegeneration and injury in the central nervous system[Show abstract] [Hide abstract]
ABSTRACT: Levels of steroids in the adult central nervous system (CNS) show marked changes in response to stress, degenerative disorders and injury. However, their analysis in complex matrices such as fatty brain and spinal cord tissues, and even in plasma, requires accurate and precise analytical methods. Radioimmunoassays (RIA) and enzyme-linked immunosorbent assays, even with prepurification steps, do not provide sufficient specificity, and they are at the origin of many inconsistent results in the literature. The analysis of steroids by mass spectrometric methods has become the gold standard for accurate and sensitive steroid analysis. However, these technologies involve multiple purification steps prone to errors, and they only provide accurate reference values when combined with careful sample workup. In addition, the interpretation of changes in CNS steroid levels is not an easy task because of their multiple sources: the endocrine glands and the local synthesis by neural cells. In the CNS, decreased steroid levels may reflect alterations of their biosynthesis, as observed in the case of chronic stress, post-traumatic stress disorders or depressive episodes. In such cases, return to normalization by administering exogenous hormones or by stimulating their endogenous production may have beneficial effects. On the other hand, increases in CNS steroids in response to acute stress, degenerative processes or injury may be part of endogenous protective or rescue programs, contributing to the resistance of neural cells to stress and insults. The aim of this review is to encourage a more critical reading of the literature reporting steroid measures, and to draw attention to the absolute need for well-validated methods. We discuss reported findings concerning changing steroid levels in the nervous system by insisting on methodological issues. An important message is that even recent mass spectrometric methods have their limits, and they only become reliable tools if combined with careful sample preparation. Copyright © 2015. Published by Elsevier Inc.Steroids 08/2015; 103. DOI:10.1016/j.steroids.2015.08.013 · 2.64 Impact Factor
Article: Intranasal delivery of progesterone after transient ischemic stroke decrease mortality and provides neuroprotection.[Show abstract] [Hide abstract]
ABSTRACT: Progesterone is a potential neuroprotective agent for cerebral stroke. One of the STAIR's recommendations is to test different routes of delivery of therapeutic agents. Here, we investigated the neuroprotective efficacy of intranasal delivery of progesterone in oleogel. Male mice were subjected to transient middle cerebral occlusion (MCAO) for 1h. Mice received intranasal or intraperitoneal administrations of progesterone (8 mg/kg) at 1, 6, and 24h post-MCAO. Plasma and brain levels of steroids were measured by gas chromatography-mass spectrometry 2 and 24h after the last administration of progesterone. Behavioral and histopathological analyzes were performed at 48h post-MCAO. For blood-brain barrier (BBB) permeability analysis, mice received one intranasal administration of progesterone or placebo at reperfusion and Evans Blue and sodium fluorescein extravasations were assessed at 4h post-MCAO. Two hours after its nasal administration, progesterone reached elevated levels in brain and plasma and was bioconverted to its 5α-reduced metabolites and to 20α-dihydroprogesterone. However, brain levels of progesterone and its metabolites were about half those measured after intraperitoneal injections, whereas levels of 11-deoxycorticosterone and corticosterone were 5-times lower. In contrast, after 24h, higher levels of progesterone were measured in brain and plasma after intranasal than after intraperitoneal delivery. Intranasal progesterone decreased the mortality rate, improved motor functions, reduced infarct, attenuated neuronal loss, and decreased the early BBB disruption. This study demonstrates a good bioavailability, a prolonged absorption and a good neuroprotective efficacy of intranasal delivery of progesterone, thus potentially offering an efficient, safe, non-stressful and very easy mode of administration in stroke patients. Copyright © 2015. Published by Elsevier Ltd.Neuropharmacology 06/2015; 97. DOI:10.1016/j.neuropharm.2015.06.002 · 5.11 Impact Factor
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ABSTRACT: Following oral or IV administration, dopamine (DA) cannot cross the blood-brain barrier to a significant extent, but can enter the brain when administered via the nasal passages. Intranasal administration of DA was shown to increase extracellular DA in the striatum, to have antidepressant action and to improve attention and working memory in rats. Here we show that aged (22-24 months old) rats are deficient in an object-place learning task, but that this learning/memory is intact and comparable with that of adult rats upon pre-trial administration of 0.3 mg/kg DA gel into the nasal passages. This result raises the possibility of the therapeutic application of intranasal DA treatment for age-related cognitive disorders.Neurobiology of Learning and Memory 10/2014; 114. DOI:10.1016/j.nlm.2014.07.006 · 3.65 Impact Factor
Article: Prepuberal intranasal dopamine treatment in an animal model of ADHD ameliorates deficient spatial attention, working memory, amino acid transmitters and synaptic markers in prefrontal cortex, ventral and dorsal striatum[Show abstract] [Hide abstract]
ABSTRACT: Intranasal application of dopamine (IN-DA) has been shown to increase motor activity and to release DA in the ventral (VS) and dorsal striatum (DS) of rats. The aim of the present study was to assess the effects of IN-DA treatment on parameters of DA and excitatory amino acid (EAA) function in prepuberal rats of the Naples high-excitability (NHE) line, an animal model for attention-deficit hyperactivity disorder (ADHD) and normal random bred (NRB) controls. NHE and NRB rats were daily administered IN-DA (0.075, 0.15, 0.30 mg/kg) or vehicle for 15 days from postnatal days 28-42 and subsequently tested in the Làt maze and in the Eight-arm radial Olton maze. Soluble and membrane-trapped L-glutamate (L-Glu) and L-aspartate (L-Asp) levels as well as NMDAR1 subunit protein levels were determined after sacrifice in IN-DA- and vehicle-treated NHE and NRB rats in prefrontal cortex (PFc), DS and VS. Moreover, DA transporter (DAT) protein and tyrosine hydroxylase (TH) levels were assessed in PFc, DS, VS and mesencephalon (MES) and in ventral tegmental area (VTA) and substantia nigra, respectively. In NHE rats, IN-DA (0.30 mg/kg) decreased horizontal activity and increased nonselective attention relative to vehicle, whereas the lower dose (0.15 mg/kg) increased selective spatial attention. In NHE rats, basal levels of soluble EAAs were reduced in PFc and DS relative to NRB controls, while membrane-trapped EAAs were elevated in VS. Moreover, basal NMDAR1 subunit protein levels were increased in PFc, DS and VS relative to NRB controls. In addition, DAT protein levels were elevated in PFc and VS relative to NRB controls. IN-DA led to a number of changes of EAA, NMDAR1 subunit protein, TH and DAT protein levels in PFc, DS, VS, MES and VTA, in both NHE and NRB rats with significant differences between lines. Our findings indicate that the NHE rat model of ADHD may be characterized by (1) prefrontal and striatal DAT hyperfunction, indicative of DA hyperactivty, and (2) prefrontal and striatal NMDA receptor hyperfunction indicative of net EAA hyperactivty. IN-DA had ameliorative effects on activity level, attention, and working memory, which are likely to be associated with DA action at inhibitory D2 autoreceptors, leading to a reduction in striatal DA hyperactivity and, possibly, DA action on striatal EAA levels, resulting in a decrease of striatal EAA hyperfunction (with persistence of prefrontal EAA hyperfunction). Previous studies on IN-DA treatment in rodents have indicated antidepressant, anxiolytic and anti-parkinsonian effects in relation to enhanced central DAergic activity. Our present results strengthen the prospects of potential therapeutic applications of intranasal DA by indicating an enhancement of selective attention and working memory in a deficit model.Amino Acids 05/2014; 46(9). DOI:10.1007/s00726-014-1753-8 · 3.29 Impact Factor
Article: Revisiting the roles of progesterone and allopregnanolone in the nervous system: Resurgence of the progesterone receptors[Show abstract] [Hide abstract]
ABSTRACT: Progesterone is commonly considered as a female reproductive hormone and is well-known for its role in pregnancy. It is less well appreciated that progesterone and its metabolite allopregnanolone are also male hormones, as they are produced in both sexes by the adrenal glands. In addition, they are synthesized within the nervous system. Progesterone and allopregnanolone are associated with adaptation to stress, and increased production of progesterone within the brain may be part of the response of neural cells to injury. Progesterone receptors (PR) are widely distributed throughout the brain, but their study has been mainly limited to the hypothalamus and reproductive functions, and the extra-hypothalamic receptors have been neglected. This lack of information about brain functions of PR is unexpected, as the protective and trophic effects of progesterone are much investigated, and as the therapeutic potential of progesterone as a neuroprotective and promyelinating agent is currently being assessed in clinical trials. The little attention devoted to the brain functions of PR may relate to the widely accepted assumption that non-reproductive actions of progesterone may be mainly mediated by allopregnanolone, which does not bind to PR, but acts as a potent positive modulator of γ-aminobutyric acid type A (GABAA) receptors. The aim of this review is to critically discuss effects of progesterone on the nervous system via PR, and of allopregnanolone via its modulation of GABAA receptors, with main focus on the brain.Progress in Neurobiology 10/2013; 113. DOI:10.1016/j.pneurobio.2013.09.004 · 9.99 Impact Factor
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ABSTRACT: Progesterone receptors (PR) are expressed throughout the brain. However, their functional significance remains understudied. Here we report a novel role of PR as crucial mediators of neuroprotection using a model of transient middle cerebral artery occlusion and PR knockout mice. Six hours after ischemia, we observed a rapid increase in progesterone and 5α-dihydroprogesterone, the endogenous PR ligands, a process that may be a part of the natural neuroprotective mechanisms. PR deficiency, and even haploinsufficiency, increases the susceptibility of the brain to stroke damage. Within a time window of 24 h, PR-dependent signaling of endogenous brain progesterone limits the extent of tissue damage and the impairment of motor functions. Longer-term improvement requires additional treatment with exogenous progesterone and is also PR dependent. The potent and selective PR agonist Nestorone is also effective. In contrast to progesterone, levels of the neurosteroid allopregnanolone, which modulates γ-aminobutyric acid type A receptors, did not increase after stroke, but its administration protected both wild-type and PR-deficient mice against ischemic damage. These results show that 1) PR are linked to signaling pathways that influence susceptibility to stroke, and 2) PR are direct key targets for both endogenous neuroprotection and for therapeutic strategies after stroke, and they suggest a novel indication for synthetic progestins already validated for contraception. Although allopregnanolone may not be an endogenous neuroprotective agent, its administration protects the brain against ischemic damage by signaling mechanisms not involving PR. Collectively, our data clarify the relative roles of PR and allopregnanolone in neuroprotection after stroke.Endocrinology 05/2012; 153(8):3747-57. DOI:10.1210/en.2012-1138 · 4.50 Impact Factor
Article: Progesterone Synthesis in the Nervous System: Implications for Myelination and Myelin Repair[Show abstract] [Hide abstract]
ABSTRACT: Progesterone is well known as a female reproductive hormone and in particular for its role in uterine receptivity, implantation, and the maintenance of pregnancy. However, neuroendocrine research over the past decades has established that progesterone has multiple functions beyond reproduction. Within the nervous system, its neuromodulatory and neuroprotective effects are much studied. Although progesterone has been shown to also promote myelin repair, its influence and that of other steroids on myelination and remyelination is relatively neglected. Reasons for this are that hormonal influences are still not considered as a central problem by most myelin biologists, and that neuroendocrinologists are not sufficiently concerned with the importance of myelin in neuron functions and viability. The effects of progesterone in the nervous system involve a variety of signaling mechanisms. The identification of the classical intracellular progesterone receptors as therapeutic targets for myelin repair suggests new health benefits for synthetic progestins, specifically designed for contraceptive use and hormone replacement therapies. There are also major advantages to use natural progesterone in neuroprotective and myelin repair strategies, because progesterone is converted to biologically active metabolites in nervous tissues and interacts with multiple target proteins. The delivery of progesterone however represents a challenge because of its first-pass metabolism in digestive tract and liver. Recently, the intranasal route of progesterone administration has received attention for easy and efficient targeting of the brain. Progesterone in the brain is derived from the steroidogenic endocrine glands or from local synthesis by neural cells. Stimulating the formation of endogenous progesterone is currently explored as an alternative strategy for neuroprotection, axonal regeneration, and myelin repair.Frontiers in Neuroscience 02/2012; 6:10. DOI:10.3389/fnins.2012.00010 · 3.66 Impact Factor
Article: Intranasally applied L-DOPA alleviates parkinsonian symptoms in rats with unilateral nigro-striatal 6-OHDA lesions[Show abstract] [Hide abstract]
ABSTRACT: l-3,4-Dihydroxyphenylalanine (L-DOPA) remains the most effective drug for therapy of Parkinson's disease. However, the current clinical route of L-DOPA administration is variable and unreliable because of problems with drug absorption and first-pass metabolism. Administration of drugs via the nasal passage has been proven an effective alternate route for a number of medicinal substances. Here we examined the acute behavioral and neurochemical effects of intranasally (IN) applied L-DOPA in rats bearing unilateral lesions of the medial forebrain bundle, with severe depletion (97%) of striatal dopamine. Turning behavior in an open field, footslips on a horizontal grid and postural motor asymmetry in a cylinder were assessed following IN L-DOPA or vehicle administration with, or without, benserazide pre-treatment. IN L-DOPA without benserazide pre-treatment mildly decreased ipsilateral turnings and increased contralateral turnings 10-20 min after the treatment. IN L-DOPA with saline pre-treatment reduced contralateral forelimb-slips on the grid while no effects were evident in the cylinder test. These results support the hypothesis that L-DOPA can bypass the blood-brain barrier by the IN route and alleviate behavioral impairments in the hemiparkinsonian animal model.Brain research bulletin 11/2011; 87(2-3):340-5. DOI:10.1016/j.brainresbull.2011.11.004 · 2.72 Impact Factor
Article: Erratum to: Brain distribution and behavioral effects of progesterone and pregnenolone after intranasal or intravenous administration[Eur. J. Pharmacol. 641/2–3]European Journal of Pharmacology 11/2010; 646(1):46-46. DOI:10.1016/j.ejphar.2010.07.021 · 2.53 Impact Factor
Article: Brain distribution and behavioral effects of progesterone and pregnenolone after intranasal or intravenous administration[Show abstract] [Hide abstract]
ABSTRACT: Neurosteroids hold great promise for the treatment of diseases of the central nervous system (CNS). We compared the uptake by 11 brain regions and appearance in blood of tritium-labeled pregnenolone and progesterone after intranasal and intravenous (IV) injection. Both neurosteroids appeared in blood and brain after either method of administration, but with important differences in uptake. Bioavailability based on appearance in arterial serum showed that about 23% and 14% of the intranasal administered doses of pregnenolone and progesterone, respectively, entered the blood. Brain levels were about two fold lower after intranasal administration for the two neurosteroids. With intranasal administration, brain levels of the two steroids did not vary over time (2-120 min), whereas brain levels were higher early (10 min or less) after i.v. administration. With i.v. administration, uptake by brain regions did not vary, whereas the olfactory bulb, hippocampus, and hypothalamus had high uptake rates after intranasal administration. Intranasal administration of prenenolone improved memory, whereas progesterone decreased anxiety, thus demonstrating that therapeutic levels of neurosteroids can be delivered to the brain by intranasal administration. The neurosteroids were rapidly degraded after i.v. or intranasal delivery, but pregnenolone was more resistant to degradation in the brain after intranasal administration and in serum after i.v. administration. These results show that either the i.v. or intranasal routes of administration can deliver neurosteroids to blood and brain, but that the two routes have significant differences with intranasal administration favoring some brain regions.European journal of pharmacology 09/2010; 641(2-3):128-34. DOI:10.1016/j.ejphar.2010.05.033 · 2.53 Impact Factor
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ABSTRACT: Testosterone influences various aspects of affective behavior, which is mediated by different brain regions within the emotion circuitry. Previous neuroimaging studies have demonstrated that testosterone increases neural activity in the amygdala. To investigate whether this could be due to altered regulation of amygdala functioning which is thought to be mediated by the prefrontal cortex, we studied the effects of exogenous testosterone on the interaction between the amygdala and other brain regions. Healthy middle-aged women received a single nasal testosterone dose in a randomized, placebo-controlled, crossover manner, and performed an emotional face matching task while their brain activity was measured with functional MRI. The results show that testosterone rapidly reduced functional coupling of the amygdala with the orbitofrontal cortex, and enhanced amygdala coupling with the thalamus. This suggests that testosterone may reduce the regulatory control over the amygdala, or that testosterone shifts amygdala output away from the orbitofrontal cortex towards the thalamus. Testosterone also reduced functional coupling with the contralateral amygdala. Because interhemispheric amygdala coupling is lower in men than in women, this result suggests that circulating testosterone may contribute to this sexual dimorphism.Psychoneuroendocrinology 09/2009; 35(1):105-13. DOI:10.1016/j.psyneuen.2009.09.007 · 4.94 Impact Factor
Article: Effects of intranasally applied dopamine on behavioral asymmetries in rats with unilateral 6-hydroxydopamine lesions of the nigro-striatal tract. Neuroscience[Show abstract] [Hide abstract]
ABSTRACT: Due to its lipophobic properties, dopamine is unable to cross the blood-brain barrier following systemic application. However, recently it has been demonstrated that, when applied directly via the nasal passages in the rat, dopamine exerts neurochemical and behavioural action, including increases of dopamine in striatal subregions, antidepressive-like action, and increased behavioral activity. These effects could potentially be mediated by exogenous dopamine acting as a direct agonist at postsynaptic dopamine receptors. However, it is also possible that intranasally applied dopamine acts indirectly via the modulation of the activity of dopaminergic cell bodies. To approach this question, the present study used rats with unilateral 6-hydroxydopamine (6-OHDA) lesions of the nigrostriatal tract, as these lesions lead to pharmacologically stimulated behavioural asymmetries which are specific for direct and indirect dopamine agonists. We found that 7 days of repeated treatment with intranasal dopamine induced a sensitization of the turning response to amphetamine, but not to apomorphine. Furthermore, intranasal dopamine dose-dependently increased the use of the forepaw ipsilateral to the 6-OHDA-lesioned side of the brain. These results suggest that intranasally administered dopamine acts via an indirect mechanism of action, putatively by increasing the release of endogenous dopamine in the brain.Neuroscience 05/2009; 162(1):174-83. DOI:10.1016/j.neuroscience.2009.04.051 · 3.36 Impact Factor
Article: Intranasal application of dopamine reduces activity and improves attention in Naples High Excitability rats that feature the mesocortical variant of ADHD[Show abstract] [Hide abstract]
ABSTRACT: Based on findings of a profound action of intranasally applied dopamine (DA) on dopamine release in the striatum, we examined the possibility that intranasal application of DA would influence indices of attention and activity in juvenile male rats of the Naples High Excitability line. This rat model features the main aspects of Attention Deficit/Hyperactivity Disorder (ADHD). Juvenile NHE rats received an intranasal application of either DA (0.075 mg/kg, 0.15 mg/kg and 0.3 mg/kg) or vehicle into both nostrils daily for 15 days. On day 14, 1 h after treatment, they were tested in the Làt maze, and one day later, in the eight arm radial maze. Activity in the Làt maze: The highest dose of DA (0.3 mg/kg) decreased horizontal (HA) and vertical (VA) activity during the first 10 min of the test. No effect was found for rearing duration (RD), which indexes non-selective attention (NSA). Activity in the radial maze: No treatment effects were found for HA and VA components, and for RD. Attention indices: The intermediate dose of DA (0.15 mg/kg) significantly improved the number of arms visited before the first repetitive arm entry in the radial maze, an index of selective spatial attention (SSA). In conclusion, intranasal application of DA reduced hyperactivity at the highest dose used, whereas the intermediate dose improved attention in an animal model of ADHD. These results suggest the potential of employing intranasal DA for therapeutic purposes.European neuropsychopharmacology: the journal of the European College of Neuropsychopharmacology 04/2009; 19(10):693-701. DOI:10.1016/j.euroneuro.2009.02.005 · 4.37 Impact Factor
Article: Delivery of testosterone to the brain by intranasal administration: Comparison to intravenous testosterone[Show abstract] [Hide abstract]
ABSTRACT: Intranasal (i.n.) administration has emerged as a strategy to deliver therapeutics to the brain. Here, we compared i.n. and intravenous (i.v.) administration for testosterone. About 75% of the i.n. administered testosterone entered the blood. However, whole brain levels of testosterone were about twice as high after i.n. administration as after i.v. administration. About two-thirds of the testosterone entering the brain after i.n. administration did so by direct entry by nasal routes and the remainder indirectly by first entering the blood and then crossing the blood-brain barrier. All brain regions except the frontal cortex had higher levels of testosterone after i.n. administration than after i.v. administration, although the differences among brain regions varied much more for the i.n. route. The olfactory bulb, hypothalamus, striatum, and hippocampus had the highest levels after i.n. administration. The brain uptake pattern suggested a variety of distribution routes likely involving the cerebrospinal fluid, diffusion through brain tissue, and transport through nerve projections. Regional distribution patterns were similar after either i.n. or i.v. administration, suggesting that the dominant factor determining distribution/retention was the same for either route of administration. We conclude that the i.n. administration route delivers testosterone systemically and can target the brain, especially the olfactory bulb, hypothalamus, striatum, and hippocampus.Journal of Drug Targeting 02/2009; 17(2):91-7. DOI:10.1080/10611860802382777 · 2.74 Impact Factor
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ABSTRACT: Although multiple forms of testosterone replacement therapy are available to treat hypogonadism, none is ideal. This article reports on the pharmacokinetics of an innovative nasal formulation of testosterone in hypogonadal men. The first study was undertaken in eight men with a baseline total testosterone (TT) of 130.8 +/- 87.4 ng/dL and examined the pharmacokinetics of nasal testosterone given in a single dose of 7.6 mg, 15.2 mg or 22.8 mg, respectively. The second study examined the pharmacokinetics of nasal testosterone (7.6 mg) given either twice or three times a day in 21 severely hypogonadal men (baseline TT in 20 patients <50 ng/dL, in one patient 152 ng/dL) for 14 days. The steady-state concentration of testosterone was within the normal range in all treatment groups, but only in the 3-times-a-day group was the 95% confidence interval completely within the physiological range. The average DHT level did not exceed the upper range of normal. The clinical global visual analogue scale improved in the whole group receiving testosterone (p < 0.001). All adverse events in both studies were of mild to moderate intensity and were evaluated as unlikely or not related to the administered study drug. No patients dropped out during treatment. Comparison with the normal circadian rhythm by computer modelling suggests that nasal testosterone can be used to mimic the normal diurnal pattern in eugonadal men. Thus, nasal testosterone can be administered safely to humans in doses that approximate serum concentrations in the normal physiological range.The Aging Male 01/2009; 11(4):171-8. DOI:10.1080/13685530802351974 · 2.00 Impact Factor
Article: Intranasal administration of progesterone increases dopaminergic activity in amygdala and neostriatum of male rats[Show abstract] [Hide abstract]
ABSTRACT: We evaluated the effects of intranasal administration of progesterone (PROG) on the activity of dopaminergic neurons in the brain of anesthetized rats by means of microdialysis. Male Wistar rats were implanted with guide cannulae in the basolateral amygdala and neostriatum. Three to 5 days later, they were anesthetized with urethane, and dialysis probes were inserted. After a stabilization period of 2 h, four 30-min samples were collected. Thereafter, the treatment (0.5, 1.0 or 2.0 mg/kg of PROG dissolved in a viscous castor oil mixture, or vehicle) was applied into the nose in a volume of 10 microl (5 microl in each nostril). In other animals, an s.c. injection of PROG (1.0, 2.0 or 4.0 mg/kg) or vehicle was given. Samples of both application ways were collected at 30-min interval for 4 h after the treatment and immediately analyzed with high performance liquid chromatography and electrochemical detection. Intranasal administration of 2 mg/kg of PROG led to an immediate (within 30 min after the treatment) significant increase in the basolateral amygdala dopamine levels. In the neostriatum, the 2 mg/kg dose led to a delayed significant increase in dopamine. S.c. administration of 4 mg/kg of PROG was followed by a delayed significant increase in dopamine, both, in the basolateral amygdala and neostriatum, but smaller in magnitude in comparison to the intranasal treatment. This is the first study to demonstrate dopamine-enhancing effects of PROG, not only in the neostriatum, but also in the basolateral amygdala. Our results indicate that the intranasal route of administration of PROG is a more efficacious way for targeting the brain than the s.c. route.Neuroscience 10/2008; 157(1):196-203. DOI:10.1016/j.neuroscience.2008.09.003 · 3.36 Impact Factor
Article: Dopaminergic and serotonergic activity in neostriatum and nucleus accumbens enhanced by intranasal administration of testosterone[Show abstract] [Hide abstract]
ABSTRACT: Testosterone was administered intranasally in anesthetized male rats, and its effects on the activity of dopaminergic and serotonergic neurons in the neostriatum and nucleus accumbens were assessed by means of microdialysis and HPLC. The treatment (0.5, 1.0 or 2.0 mg/kg of testosterone or vehicle, 10 microl volume) was applied in both nostrils, half (5 microl) into each. Subcutaneous injections of testosterone (2.0, 4.0 or 8.0 mg/kg) or vehicle were tested in other subjects. Samples were collected for 5 h. In the neostriatum, an increase of dopamine occurred after 2.0 mg/kg. Serotonin levels increased after 1.0 mg/kg dose. In the nucleus accumbens, dopamine and serotonin increased after 1.0 mg/kg and 2.0 mg/kg doses. Subcutaneous administration of 8.0 mg/kg testosterone increased dopamine and serotonin in the neostriatum only. We conclude that intranasal administration of testosterone is a more efficacious way for targeting the brain than the subcutaneous route, and may be considered as a means to activate central dopaminergic and serotonergic systems.European neuropsychopharmacology: the journal of the European College of Neuropsychopharmacology 10/2008; 19(1):53-63. DOI:10.1016/j.euroneuro.2008.08.003 · 4.37 Impact Factor
Article: Testosterone biases automatic memory processes in women towards potential mates. Neuroimage[Show abstract] [Hide abstract]
ABSTRACT: Female mate choice involves the comparative evaluation of potential mates. Females use a pooled comparison of sampled males to maximize the perceived reproductive fitness of their partner, implying the memorization of sampled males. However, hormonal and reproductive states influence female choosiness, and women's preference and memory for masculinity. Here, we investigated whether testosterone biases memory processes in women towards male faces using functional MRI. A single nasal testosterone dose was administered to healthy women in their early follicular phase, in a double-blind, placebo-controlled, crossover design. Testosterone increased the difference in reaction times to categorize male and female faces during encoding, without influencing subsequent recognition accuracy or response bias. The imaging results showed that testosterone shifted memory formation in the hippocampus and inferior temporal gyri from the encoding of female faces towards the encoding of male faces. In contrast, testosterone shifted memory formation in the left inferior frontal gyrus from the encoding of male faces towards the encoding of female faces. Furthermore, the hippocampal contribution to memory retrieval also shifted from female towards male faces. These results indicate that testosterone biases memory processes towards the relatively automatic encoding and retrieval of males in temporal brain regions and elaborate encoding of females in frontal brain regions, suggesting that testosterone may support female mate sampling and comparison by biasing automatic memory processes towards the encoding and retrieval of potential mates.NeuroImage 08/2008; 43(1):114-20. DOI:10.1016/j.neuroimage.2008.07.002 · 6.36 Impact Factor
Article: Behavioral Actions of Intranasal Application of Dopamine: Effects on Forced Swimming, Elevated Plus-Maze and Open Field Parameters[Show abstract] [Hide abstract]
ABSTRACT: Recently, we found evidence that intra-nasally administered dopamine (DA), can enter the brain, leading to an immediate increase in extracellular DA levels in striatal subregions. This offers a potential alternative approach to target the brain with exogenous DA, which otherwise cannot cross the blood-brain barrier. Here, we examined whether intra-nasally applied DA also exerts behavioral activity on mesocortical and nigrostriatal dopaminergic functions. Male Wistar rats (3-4 months) were tested for potential behavioral effects of intra-nasally applied DA (0.03, 0.3 or 3.0 mg/kg) in the forced swimming test (FST) for antidepressant-like activity, elevated plus-maze for anxiety-related behavior, and on motor activity in a novel and familiar environment. Intra-nasally administered dopamine in a dose of 0.3 mg/kg exerted antidepressant-like activity in the FST, but had neither anxiolytic-like nor anxiogenic-like effects in the elevated plus-maze. Furthermore, intra-nasal dopamine stimulated locomotor activity in a familiar, but not novel, open field. These results support the view that intra-nasally applied DA can act on the central nervous system by entering the brain via the nose-brain pathway, making this kind of application procedure a promising alternative for targeting the brain, and thus treating disorders involving mesocortical and/or nigrostriatal dopaminergic disturbances.Neuropsychobiology 02/2008; 57(1-2):70-9. DOI:10.1159/000135640 · 2.26 Impact Factor
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ABSTRACT: Testosterone modulates mood and sexual function in women. However, androgen levels decline with age, which may relate to the age-associated change in sexual functioning and the prevalence of mood and anxiety disorders. These effects of testosterone are potentially mediated by the amygdala. In the present study, we investigated whether the age-related decline in androgen levels is associated with reduced amygdala activity, and whether exogenous testosterone can restore amygdala activity. Healthy young and middle-aged women participated during the early follicular phase of the menstrual cycle, and amygdala responses to biologically salient stimuli were measured with functional magnetic resonance imaging (fMRI). Androgen levels were lower in middle-aged than young women, which was associated with decreased amygdala reactivity. Endogenous testosterone levels correlated positively with amygdala reactivity across the young and middle-aged women. The middle-aged women received a single nasal dose of testosterone in a double-blind, placebo-controlled, crossover manner, which rapidly increased amygdala reactivity to a level comparable to the young women. The enhanced testosterone levels correlated positively with superior frontal cortex responses and negatively with orbitofrontal cortex responses across individuals, which may reflect testosterone-induced changes in amygdala regulation. These results show that testosterone modulates amygdala reactivity in women, and suggest that the age-related decline in androgen levels contribute to the decrease in amygdala reactivity.Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology 02/2008; 34(3):539-47. DOI:10.1038/sj.npp.2008.2 · 7.05 Impact Factor
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Chez Lili Holiday cottage / home
from £72 /night help Price for guests, Nights approx:
9 reviews
from £72 /night help Price for guests, Nights approx:
Estimated nightly price based on a weekly stay. Excludes fees (if applicable). Enter your dates to see the total cost.
House / 2 bedrooms / sleeps 4 Home 208273
Availability Your dates are available
House / 2 bedrooms / sleeps 4
|Key Info
Chez Lili is a special 200 year old detached house set in its own private garden in the charming hill village of Carsac de Gurson Perfectly located to sample the delights of the region, the house has been restored to an exceptionally high standard and looks out onto adjacent sweeping gardens and stunning views.Chez Lili is complemented by the private pool which is exclusively for guests use and luxuriously large Jacuzzi . Chez Lili is ideal for discerning guests who desire higher standards of quality and comfort and has been classified as 4 star accommodation by 'Hotelplan' and 'Creme de la Creme' for four consecutive years with 'Just France Inghams'. Chez Lili has a maximum rating on Trip advisor.Chez Lili has been designed to provide for all needs. Whether you desire a Family holiday, Romantic break or perfect honeymoon location Chez Lili can provide the answer.The spacious accommodation is thoughtfully laid out over two floors and always maintained in excellent decorative order The large ground floor has a large traditional country kitchen with modern appliances and farmhouse dining table. The beamed lounge features a large picture window from which to admire the surrounding countryside. Comfortable quality furnishings complement the room, which has a widescreen 40 inch Satellite TV, DVD, and a fireplace with a log burner. Free Wi fi is provided. Together with optional air conditioning.The family bathroom has all facilities including a full size bath. Upstairs, the charming master bedroom has beams in Beech and Oak. The 1.8metre bed is in traditional style. The second bedroom has ensuite shower and toilet facilities. There are two twin beds with the option of a childrens cot. There is a further small single bedroom on the ground floor which adds to the versatility of the house .A great deal of thought has gone into making Chez Lili comfortable, welcoming and pleasing to the eye. Our aim is to provide you with the ingredients for a special holiday with exemplary standards of care, cleanliness and service. Welcome pack provided.
|Sleeps up to 4, 2 bedrooms
|2 bedrooms, 2 bathrooms of which 1 Family bathrooms and 1 En suites
|Nearest beach
|Lac de Gurson 1 km
|Will consider
|Corporate bookings, House swap, Long term lets (over 1 month)
|Car advised
|Nearest Amenities
|1.5 km
|Nearest travel links
|Nearest airport: Bergerac 35 km, Nearest railway: Montpon 12 km
|Family friendly
|Great for children of all ages
|Pets welcome, No smoking at this property
Features and Facilities
|Jacuzzi or hot tub, Log fire, Internet access, DVD player
|Private outdoor pool (unheated)
|Central heating, Air conditioning, TV, CD player, Satellite TV, Wi-Fi available
|Kettle, Toaster, Iron, Hair dryer
|Clothes dryer, Dishwasher, Cooker, Microwave, Fridge, Freezer, Washing machine
|Double beds (1), Single beds (3), Cots (1), Dining seats for 4, Lounge seats for 6
|Linen provided, Towels provided, High chair
|Private outdoor pool (unheated), Balcony or terrace, Private garden, BBQ, Bicycles available
|Parking, Not suitable for wheelchair users
|Further details outdoors
A luxurious. covered, 6 person Jacuzzi spa and private pool are provided for guests use. The pool is positioned to survey the stunning views across the adjoining vales and is exclusively for the use of the guests at Chez Lili .Sun loungers and furniture are provided.The Private gardens have an abundance of fruit trees. From the front garden there are stunning views across the adjacent private parkland. In the rear garden a covered terrace surrounded by mature walnut trees and vines can provide a break from the sun and is the perfect place for alfresco dining.In addition to the front and rear gardens there is extensive privately owned parkland adjacent to the house. . This is available for your pleasure and recreation and leads to beautiful walks in the surrounding countryside.Within walking distance is the amazing newly renovated Lac de Gurson which is now a major regional attraction complete with beautiful beach, restaurants, bars ,Horse riding, canoeing, fishing and numerous other leisure pursuits.Chez Lili is situated in a perfect position from which to explore the delights of the region. From the beautiful cuisine to the stunning architecture of nearby Saint Emilion and Bordeaux.
|Further details
TO RESERVE PLEASE CONTACT THE OWNER .Upon reservation a 50 percent deposit will be required , the balance of rental charges will be payable 8 weeks prior to the holiday period. A security deposit (refundable)of 250 euros will also be required at the time of final payment. PAYPAL AND CREDIT CARDS ACCEPTED.Bookings are normally accepted from Saturday to Saturday for a seven day period , however subject to availability short breaks will be considered. Optional Air-conditioning is fitted in the lounge area for your added comfort . A supplement of 30 euros per week is charged to cover energy costs should you wish to take advantage of this facility on those hotter days.An small additional charge may be made in winter months for additional heating costs. This is based on consumption.
The Dordogne region
The Dordogne remains one of the prettiest regions in France. It has the rare combination of warm climate with extended summers and a green and pleasant landscape dotted with vineyards.
Chez Lili is perfectly located to take advantage of the many things on offer in the region. Whether you prefer to relax by a pool , take part in leisure activities or explore local historical sites, culture and cuisine it is all here. Lakes and rivers abound with numerous waterside beaches and activities. Charming towns and villages with medieval architecture are here to explore.
Visit Bordeaux and sample life in a beautiful city sitting on the banks of the mighty Gironde estuary.
Chez Lili is situated in a prolific wine producing area. Close to probably one of the most acclaimed wine regions in the World , St Emilion. Visit a vineyard and sample the local products. Something not to miss.
Visit Bergeracs charming 'old town or Brantome, with its two rivers . Sarlat's medieval town is beautifully preserved.
The caves paintings at Lascaux provide a thoughtful interlude.
Carsac de Gurson
Within 100 metres of the villages Chateau and 11th century church Chez Lili surveys the beautiful countryside with its deep forests and vineyards hugging the surrounding hills, One of which retains the ruin of Chateau De Gursona 14th century Chateau which stands watch over Carsac giving a reminder of the magnificent history of the area.
A tour can be arranged in the village vineyard. The next village,Villefranche de Lonchat, has local shops and bars and a typical French atmosphere, both are a very short ride away.Sample the delights of Villefranches night market where superb local cuisine combines with music and fine wine , irresistable.
Relaxing in the square at St Foye La Grande with a coffee and patisserie is the only way to comprehend the irreplaceable magic of a traditional French market. Numerous other markets take place throughout the week. The beautiful towns of Domme, Beynac, La Roque-Gageac and Bergerac are within easy reach. The caves paintings of Lascaux provide a thoughtful interlude.
Below the village is Lac De Gurson, a 70 hectare leisure lake. This has a beach, tennis courts, horse riding, canoes, the splendid fishing, cafes and restaurants. In the evening the beach bar has music and occasional entertainment. Bikes are available by local arrangement to explore the surrounding countryside.
Whether you wish to canoe on the Dordogne, play golf at Chateau Vigiers or just relax in the sun there is something nearby for everyone.
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Add your voice to the conversation about this holiday home and your review will appear on TripAdvisor too.Write a review
9 Mar 2012
"Absolutely wonderful -an enchanting experience."
What can we say? We have stayed at Chez Lili four times now- yes we are hooked!!!! The gite is very comfortable with a lovely kitchen! So cosy- you feel at home as soon as you walk through the door. The owners are very kind and considerate- like family!!! The area is lovely and quiet but within a 10 min drive of the local supermarkets which sells everything you need and more. The lake is close by with cafe and bar. Pool is sparkling with fantastic views- fabulous for sitting around with a cool bottle of Chardonnay!!! You could do the same in the hot tub!!!! We will no doubt return and see Paul & Lisa again soon!!!! Good times!!!!
4 Mar 2012
"Fabulous French Rural Experience"
This very spacious gite is very comfortable and a perfect location for a French vacation. Cook wonderful meals in the well equipped kitchen after shopping one of the local markets. Perfect base for visiting St Emillion, Bordeaux and more. Quiet village great for walks and bike rides. Nearby restaurants were good. Hosts Were helpful and not intrusive. Cannot wait to return!
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You're booking with
Lisa and Paul E.
- 3 Years listed
55% Response rate
Calendar last updated:23 Nov 2015
Based in France
- English
- French