text:
HCPL branches will close at 5 PM on Wednesday, November 25 and will be closed through Sunday, November 29 for Thanksgiving.
Lone Star College - Cy-Fair Library and Lone Star College - Tomball Community Library will be closed all day Wednesday, November 25.
All locations will reopen on Monday, November 30 for regular hours.
ADA Info
C-SPAN will be rolling up to the Northwest Branch Library THIS Saturday, February 12th at 10:00 AM. They will be here for a short time and plan to leave by 11:30 AM. Don't miss your chance to visit this mobile BookTV studio! Learn about how BookTV is filmed. Sit in the BookTV interview chairs and learn how to film your own Book TV session! The Book TV Bus vignettes are available online. Be sure to check out a few before the bus arrives. Get on the bus and you won't to be left out in the cold. (brrrrrr...)
Harris County Texas
Mobile Site
About the Library
Locations & Hours
Holiday Closings
Library Cards
Military Library Cards
HCPL Digital Media Catalog
Interlibrary Loan
Meeting Rooms
Purchase Suggestion
Library Jobs
Job Search Guide
Frequently Asked Questions
Ask a Librarian
Staff List
Connect with HCPL
Staff Login
Information for Persons with Disabilities: Harris County Public Library will make reasonable accommodations for persons with disabilities who are interested in attending library programs. To make a request for yourself or someone you know, please notify the Branch Librarian two working days in advance of the program.
The Harris County Public Library Website by Harris County Public Library is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 United States License. It is designed for 1024x768 resolution and Internet Explorer 7+, Firefox 3+, and Safari 3+ browsers. For additional information, see our Credits page.


text:
Lifetime Service Plan
5YR Warranty
Roadside Support Plan
Sat Nav Update Plan
New Cars
Take a look at your local Dealerships New car inventory.
Demo & Pre-Owned Cars
Take a look at your local Dealerships Demo & Pre-Owned car inventory.
Calculate your service costs
Enter in the details of your car and easily calculate your next service cost
Your Service Passport
Take a look at your full service history and keep track of whats upcoming
Book your next service
You can now easily book your service online from the comfort of your home
Online Service Reminders
You'll never miss a service with timely online reminders
Attend Sponsored Events
Find out about upcoming Hyundai sponsored cultural and sporting events
Manage your contact details
Manage your contact details online so that you're always up to date
Access vehicle care
Access care and maintenance advice on your Hyundai vehicle
Competitions and giveaways
Take part in exclusive competitions and giveaways for your chance to win
Book a Service
Keep me informed
Find a dealer
Contact Hyundai
You are here:

subset: commoncrawl


text:
As You Were #4: Living Situations
( November 24, 2015 ) Last Gasp has joined forces with fellow San Franciscans Silver Sprocket to co-publish the latest edition of the on-going punk comic anthology series As You Were. This edition's theme is "living situations" and includes punk comic artists like Liz Prince (Tomboy, Adventure Time), Liz Suburbia (Sacred Heart), Ben Snakepit (Razorcake), Rachel Dukes (Boom Studios, Frankie), and many more. READ MORE


text:
Expert Service 1-877-289-7664 [Hours]
JL Audio CS112-WXv2
Subwoofer System with Single 12WXv2-4 Subwoofer & Sealed Enclosure
This item is backed by our VIP Guarantee
Get FAST answers from customers ASK a Question See questions answers
Subwoofer Features:
- Power Handling:
- RMS: 200 Watts
- Impedance: 4 ohms
- Proprietary dynamic motor analysis (DMA) improves motor behavior
- Elevated frame cooling delivers cold air above the top plate to the voice coil
- Resists breakdown under extreme conditions
- Integrated foam rear gasket which provides an optimal seal
- Polypropylene cone material
- Foam surround type
- Frequency response: 22-250Hz
- Sensitivity: 87.17dB
- 2 Year Manufacturer's Warranty
General Enclosure Features:
- Sealed Subwoofer Enclosure
- Subwoofer mounting depth: 5-5/16"
- Subwoofer cutout diameter: 11-1/16"
- Dimensions: 19-1/2"W x 15-1/4"H x 11-3/4"D
Subwoofer Specifications
If the loaded enclosure or amplifier and subwoofer package includes more than a single subwoofer, then this is the total RMS power handling for all of the subs combined.
The RMS power is the amount of power the speaker requires to operate safely and properly. RMS Power Handling refers to the amount of power a speaker can handle on a continuous basis. We recommend giving your subwoofer(s) 75% - 90% of the recommended RMS rating.
Efficiency (1w/1m) is not an accurate indicator of a subwoofer's output capability and should not be used as a comparison to other speakers or subwoofers to determine which one is "louder".
Enclosure Specifications
Sealed - Sealed boxes are those that have no holes or vents in it. The only hole in a sealed box is where the subwoofer is installed. Smaller sealed boxes require more power than a larger sealed box. They provide a tight, accurate bass, while the larger sealed enclosures provide a "boomier" and louder bass.
Ported / Vented - Ported/Vented Enclosures provide an even boomier, louder bass, but less accurate then a small, sealed box. Ported enclosures typically require more airspace per sub and also less power output from an amplifier to perform correctly.
Bandpass - Bandpass enclosures make subwoofers perform efficiently, but loose. The bass is not as "boomy" as a ported enclosure nor as punchy as a sealed enclosure. Bandpass enclosures work well with lower to mid-level subwoofers.
Specials with this Item
Warranty and Return Policy
Summary of Customer Ratings & Reviews
25 ft. of True 12 Gauge EnvyFlex Speaker Cable/Wire (100% Oxygen-Free Copper)
Your Price $39.99
20 Square Feet of Sound Dampening Material (Five 18" x 32" Pieces)
Your Price $59.99
Universal, Professional Heavy Duty Roller for Sound Damping/Dampening
Your Price $7.99
Complete Car Stereo Tool Kit, Includes Voltage Test Light, Wire Stripper and More
Your Price $16.99
Product Summary
Model Number
Internal SKU
Internal Product ID
Wiring Diagram Legend
Warning: The image depicted shows the resistance change when wiring multiple subwoofer terminals. Please refer to your subwoofer's owner's manual for the proper wiring of its terminals. Sonic Electronix, Inc. is not responsible for damage caused to your audio system or vehicle due to improper installation. Please call tech support at 1-877-289-7664 if you require additional assistance.
Product Name: JL Audio CS112-WXv2
The Sonic Advantage
What gives Sonic the edge over the competition
Fast & Free Shipping
We offer free shipping on thousands of popular items for our Continental US customers and discounted rates for international customers. With multiple warehouses across the US, most orders are delivered within 3 days!Learn More
Low Price Guarantee
We pride ourselves on offering the best products at the lowest prices. If you find an identical item on another website with a lower price, we will discount our price by 105% of the difference. Some restrictions apply.Learn More
60-Day Money-Back Guarantee
Have a problem with your order and need to return an item? Our generous 60-day return policy allows you to return items for your money back. Should your product have a defect, we will exchange, issue store credit, or repair the product for the entire length of the warranty.Learn More
Free Lifetime Tech Support
Our knowledgeable staff of industry professionals and certified installers is ready to help you pick the right product for your needs. We will help you with the setup, installation, and use of your new products.Learn More
Returns Made Easy
We want your online shopping experience to be easy and convenient. In case you need to return an item, our customer friendly return policy makes it easy.
60-Day Money-Back Guarantee
Have a problem with your order and need to return an item? Our generous 60-day return policy allows you to return items for your money back. Should your product have a defect, we will exchange, issue store credit, or repair the product for the entire length of the warranty. Learn More
No Restocking Fees
That's right, 100% refund on complete, like new returns. Learn More
365-Day Coverage
Let's face it, electronics break. We've got you covered for a full year. Learn More
Easy Return Shipping
Request a return, use our shipping label, and ship it back. Learn More
In-House Experts
Each of our employees are true experts with real life experience and passion for the products. Our team is always committed to providing you with electronics you'll enjoy.
Always available to answer your questions
Our trained install professionals can tackle any install challenge
Research & How To
Browse our online library of educational resources to learn more about the items you are looking for. Our experts have developed many tools, written many articles, and numerous videos to help you find the best item for your needs.


text:
Looking ahead
Today: Off
Tuesday: 3:40 p.m. On the air: FSSD; 1090-AM
Dodgers RHP Zack Greinke (0-0, 0.00 ERA) at Padres RHP Ian Kennedy (0-0, 0.00 ERA), 3:40 p.m.
Wednesday: 7:10 p.m. On the air: FSSD; 1090-AM
Dodgers RHP Dan Haren (0-0, 0.00 ERA) at Padres RHP Tyson Ross (0-0, 0.00 ERA), 7:10 p.m.
The conversation on Tuesday, naturally, will at some point land on Ian Kennedy's date with the Dodgers. Only, the Padres right-hander isn't interested in revisiting the melee that broke out last June when he plunked Zack Greinke — who also happens to be on the mound Tuesday — in the head while still with the Diamondbacks.
Kennedy isn't thinking too much about the rockiest spring of his career, either. The important thing, the 29-year-old said Sunday afternoon, is his right arm is in shape heading into the season.
"To me what's important about spring training is that we get ready — to come out of it healthy," said Kennedy, who posted a 6.33 ERA over six spring starts in the Cactus League. "I felt great. I really don't care about the numbers. When you're competing for a job, it makes a difference … but going into the season I feel really good. Every time I threw a bullpen I felt good.
"I'm ready for the Tuesday start."
Although Kennedy's initial return trip to the mound against Los Angeles went down without much drama last July, the game provided plenty of tense moments, especially on a play at the plate in which Yasiel Puig collided with Arizona catcher Miguel Montero.
Puig was also in the middle of the flare-ups the previous month, which started when Kennedy hit the high-energy Cuban in the nose with a fastball. After Greinke retaliated with a pitch buried into Montero's back, Kennedy's first pitch in the seventh hit the Dodgers pitcher as benches emptied in a brawl that saw half a dozen players and coaches ejected.
"It just got away from me a little bit," Kennedy told MLB.com in Los Angeles last June. "I was really trying to go inside because I didn't think it was right what he did to Miggy."
Kennedy ultimately served a 10-game suspension for his role in the melee. A month later, the Dodgers weren't looking for retribution in a one-run game — in the middle of a division race with the Diamondbacks, no less — when Kennedy stepped into the batter's box for his lone plate appearance against Ricky Nolasco.
Jeff Sanders


text:
One of the most common questions for home buyers is whether an area is safe. Below, Movoto Real Estate has listed the five safest neighborhoods in Atlanta. To create this list, we researched the total number of property and violent crimes in an area. The information is presented as crimes per 100,000 people, in order to normalize the data for more accurate comparisons.
This east side neighborhood is safer than 84.4 percent of neighborhoods in Atlanta, making it the fifth safest area on our list. Poncey-Highland, home to the Jimmy Carter Presidential Library and numerous historical buildings, has a crime index that is 59 percent lower than Atlanta's average. Annually, there are an estimated 3,407 crimes per 100,000 people in Poncey-Highland. Atlanta sees a 8,517 crimes per 100,000 people annually.
The fourth safest neighborhood on our list is Morningside-Lenox Park, a mostly residential area that is comprised of several subdivisions, including Morningside, Lenox Park, University Park, Noble Park, Johnson Estates, and Hylan Park. Morningside-Lenox Park is 87.5 percent safer than other Atlanta neighborhoods. Residents of the area have a 1 in 30 chance of being the victim of a crime.
In the past year, there were an estimated 3,407 crimes per 100,000 people in Inman Park. Residents of the east side neighborhood have a 1 in 30 chance of being a victim of crime, either property or violent. By comparison, Atlanta residents on average have a 1 in 12 chance of being the victim of a crime. This makes Inman Park safer than 90.6 percent of Atlanta neighborhoods.
The second-safest neighborhood in Atlanta is Buckhead, an uptown district in Atlanta's northside. The area is 93.8 percent safer than other Atlanta neighborhoods. Residents of Buckhead have a 1 in 175 chance of being a victim of violent crimes and a 1 in 36 chance of being a victim of property crime. Total crime in the neighborhood is 59 percent lower than the Atlanta average.
The safest neighborhood in Atlanta is Oakdale. The neighborhood is 96.9 percent safer than other Atlanta neighborhoods. Safety, however, comes at a cost. On average, the cost of living in Oakdale is higher than in the rest of the Atlanta. This is mostly because of the high cost of owning a home in the area. The median value of a home in Oakdale is $858,270, more than twice the $231,800 median value of a home in Atlanta.
Movoto provides every Atlanta real estate listing that's currently for sale. Because Movoto is a licensed brokerage, we have access to the most up-to-date data on single family homes for sale in Atlanta, GA and across Georgia. If you're looking to get more information on the 2,751 homes for sale in Atlanta, check out our detailed graphs and charts with this city's market trends. You can also search in surrounding neighborhoods and ZIP codes like: ATLANTA NORTH 1 and 30349. When you're ready to go see one of the 39 open houses, you can talk to one of the 277 Movoto Certified real estate agents in Atlanta. Remember, Movoto is always free to use without any pressure to buy.


text:
More than 165 Girls Attend 10th Annual Women in Engineering Day.
Faculty Art Show at Lilley Library through February.
Chemistry major helps in search for cheaper solar energy.
Plastics Engineering Technology students share travel log from trip to Denmark and Sweden.
New monument honors Mary Behrend.
Penn State Erie, The Behrend College | 4701 College Drive, Erie, PA 16563 | 814-898-6000 | Toll-free: 866-374-3378
Website Feedback | Site Map | Login
The Pennsylvania State University © 2015


text:
"Google Street View Reveals Grand Canyon"
"You've used Google's Street View to navigate unfamiliar cities. Now, you can use it to explore a river."
Jump to navigation
"You've used Google's Street View to navigate unfamiliar cities. Now, you can use it to explore a river."
"Last month, Tesla Motors, the maker of high-end electric cars, announced plans to open the world's largest battery plant in 2017. The goal is to overcome what it calls the biggest obstacle to meeting increased demand for its vehicles: a reliable supply of the advanced batteries that power them."
We all know it. Some agencies and organizations publish data in PDF format to keep journalists and the public from using the raw data. Take heart. Help is on the way with one easy software tool — Tabula.
"A massive machine — longer than a football field — is munching away beneath Washington like a giant earthworm. Before it's done, it will devour about 2 million cubic yards of soil that has been sitting under the city since the days of the dinosaurs."
A new USGS database gives you downloadable information on some 47,000 wind turbines in the United States. This allows environmental journalists to come up with all kinds of local, regional, or national stories about wind energy and its impacts.
Will the Federal Aviation Administration make drone journalism illegal? The first answer is likely to come soon. Connecticut journalist Pedro Rivera filed suit February 18, 2014, against Hartford police officers who he said violated his First Amendment rights to gather news.
"Glowing reindeer can be spotted in northern Finland thanks to a reflective spray which makes them more visible in a bid to prevent car accidents, Finnish reindeer breeders said on Tuesday."
"Several years ago, a group of American cockroaches discovered four strangers in their midst. A brief investigation revealed that the interlopers smelled like cockroaches, and so they were welcomed into the cockroach community. The newcomers weren't content to just sit on the sidelines, however. Instead, they began to actively shape the group's behavior. Nocturnal creatures, cockroaches normally avoid light. But when the intruders headed for a brighter shelter, the rest of the roaches followed."
"A satellite orbiting Earth has spotted 55 southern right whales hanging out in the shallow waters off Argentina."
"U.S. scientists announced on Wednesday an important milestone in the costly, decades-old quest to develop fusion energy, which, if harnessed successfully, promises a nearly inexhaustible energy source for future generations."


text:
Adopted by a Native American family as a child, Ana Elena Rafael travels back to Peru, her native country, years later, hoping to learn about her parents. On the plane, she meets businessman Mason Ridfort, who attaches himself to her and helps her find the people and places she needs. But Ana doesn't know that Mason has an ulterior motive; a warrior in the fight for good, he believes Ana may be evil and needs to make sure she isn't. Ana, meanwhile, is terrified of the man who keeps appearing in her dreams -- a man who says he's her father. Lindsay McKenna's Dark Truth (4) brings readers into a fantasy world where good and evil battle each other for dominance in our world. McKenna's description is excellent, and her story is action-packed.
Reviewed by:
Alexandra Kay


text:
These Free Verse Heaven poems are examples of Free Verse poems about Heaven. These are the best examples of Free Verse Heaven poems written by international PoetrySoup poets
If you don't find the poem you want here, try our incredible, super duper, all-knowing, advanced poem search engine.
Liquid Heaven
A feast for my womanly inner beast!
I tease, I please, you have me on my knees
I wring my hands, you oint my head
With your fingers locked in my hair of red
You -I call Master!
Begging for forgiveness, in a position of love
My words are bashing with one stuttering sound
Moaning & Moaning,
As you make my head spin like a merry-go-round
Craving for you to unleash a liquid heaven sound
My body speaks and mumbles a language meant for you
A touch of intimacy, that lathers up like liquid glue
Sticky but, yet so compelling
My tongue slips silent beloved words of joy into the air
You play the master of this dark solid room
This dungeon's all I consume
You engage me, to provoke you with everything I got
Yelling, please master don't ever stop!
At this moment, I yearn for excitement
To feel the arousing sensation of your presence
That melts me and chill me with a flow that does not kill
I'm your thinker
Your muse and poet
You are my composer creating liquid tunes
Come here and expresses the hardness of your boldness
I confess to you my love
You are all I'm dreaming of
You drive your hands all over
Reaching every steamy spot
Encourage me to stimulate your mental needs
You are the master withholding a liquid element
In me, you release fluids that hit like a silent tide
A desire that comes with a full force of the fire inside
I crave for the taste of your lips
Your hands on my hips
Your fingers with a tight sensual grip
I dedicate my heart and my lust
To get lost within every push of your trust
Like a treasure deep underneath the sand
I'm addicted to the feelings of your command
Your hazel eyes are the sunrise
You bring out the obsession,
And my sweet tooth temptation
Like the moon above a misty night
Seducing me in every way in a poetic write
Your liquid heaven is the beginning-
-Of my delicious delight!
by: PD
**A sweet Dedication To My Babe**
Copyright © Poet Destroyer A
Iris sun fades and so does the day
whispers the carried in the silence of night glowing
Wishes floating on silver trails faraway
The image of your face will forever bounded to this world
Angels Brought you to me made a lightening
sparkling diamonds in the misting treasures gems so bright
Ice roses turns into a steaming jungle of quivering glass
Flashing in the distance, in the moon light
and all of its stars, that's where the angels dancing
A beautiful adventure picture sparklers on a winter night
A cold moon dressed in dark velvet
with a pearl milky white smile beams
Sparkling jewel crystal lights up
stars blinking silver awakening
warm invading darkness your light
My life has at last found its light and its hope
Soulful cries a wolf dressed in winter clothes
faraway over ocean waves
carries in a wind's whisper sweet music dances
A magical night that will set the spirit free
Silently breathes out a puff of magic sweetly
beauty enchants warmly etching strikes
frosted fingers cracking ice deeply echoes
Striking inside bells toll warmly skipping drumbeats
bouncing of chamber walls loving tunes
Believing in your love a dream
Which enchants music of the butterflies dance
howling clouds out steaming warm sighs fluttering warmly
I closed my eyes at the end of the road
and thought of the stars
and the reason earth spins around the sun
A co write written by Liam Mcdaid and
Anne- Lise Andresen :) - 28.12.2014 -
Copyright © All Rights Reserved
Copyright © Anne Lise Andresen
After a long and stressful day
Running the bath and adding scented oils
Watching the bubbles foaming and frothing
Climbing into the deep soapy suds
Sensational scent of lavender rises
Relaxing in the steamy atmosphere
Blissfully all my troubles melt away
Drying myself in a soft warm fluffy towel
Climbing into freshly laundered sheets
Sheer bliss!
21st January 2015
~awarded 1st Place~
Indulgence Contest - Shadow Hamilton
Copyright © JAN ALLISON
Such a romantic place on a beach in Monte Carlo
Simple little things in life catching one's breath
Moonlight glinting of waves breaking off a white sandy beach
Faraway thoughts brown eyes crying in an ocean dream song
Spell of romance makes one forget the sense of anything
Silent whispers echoes binding our chain together tides speak
Do you remember the white doves that followed us along the beaches
Each link in your arm magic walks closer feelings sing inside a joyous choir enchants
Nature nurtured by the desire to fulfill dreams makes time stop
Holds deep sea emotions a galloping white steed races home in warm waves kiss
The natures mesmerizing perfume of fragrant flowers
Where destiny paints the joy in butterflies dance on a warm loving breeze
Such is the passion in the depths of ones soul
Jewels needle vision flies without wings heaven sings in a spiral coloring rainbows
No barriers closed no reasons withstand
The midnight moon shades blue embraced one shadow two become one dream
A co write written by Liam Mcdaid
and Anne-Lise Andresen :) - 30.01.2015 -
Copyright © All Rights Reserved
Her insecurity would not let her see,
I wanted her!
I thought she knew, my heart was opened.
I should've asked.
She walked on a thread, fourteen stories high
to cross from her building to mine.
The devil at her side, he cut her angel wings,
watched her drop, caught her in his wicked trap.
She was weak from years of abuse.
I heard her yell.
"Promise me this, what I sign
affects me and only me."
The devil answered, "I promise!"
No he did not lie.
Still for he It was Goodbye.
She signed his contract blind.
It was me she had dealt for.
Afraid to believe. Scared to accept,
what she knew, what she felt.
Her sense of trust for anyone long ago expired!
The man with the black blood ignored me!
I felt him; his chill was in the air.
Punished to live forever cold.
Even his pit of endless fire barely took the edge off.
"My misery of doubt is at an end!" she said.
He lowered his head in shame. That too was his curse,
he still felt remorse No matter how briefly.
She had to have me unconditionally.
If only she had known, she already owned me.
Her depth and strength impresses me
yet I know she could not stop what she had started.
She signed in blood, signed to guarantee
she would never again be alone, never again be without love!
I knew he was at our wedding, I heard the chatter of his teeth.
When I said I do it was Lucifer who stood there
him who heard my truth.
Without changing a thing, his contract he fulfilled.
I could only smile. How cold he is, the pain he sustains
for the decision he had made, when he left heaven's gate!
She hugged him on his way out.
I believe now, as I did then, as I always will for a brief moment,
his teeth stopped. For just seconds while in her arms he felt warm.
I wonder what he thought.
Let the celebration begin she owns me,
it's off to our room to be alone and in bed.
In what we did, we felt as if we were walking
innocently along a beach on the Caribbean Sea
I am the town she grew up in, her friend
her partner, and yes I am her lover.
For that her soul she traded. She had her man.
My soul she saved, my human form hers,
her kindness I return in something I know
though still in my youth my card would fall
early from the deck.
Yes he knew it too my time was short. I have only ten years left.
I held my wife all that time, made with her children from paradise!
He could not strike a deal in which he did not cheat.
He thought, ten years was for him a good deal.
The final laugh is mine, with my Angel on my side
I strike a deal, trade my soul for my wife's.
The devil acts unattached.
I beat him.
He'll feel colder now, that's the deal.
His warmth he seeks, in any soul
he can deceive. Now her soul he'll
never have. It is I who wins.
I who is eternally damned.
In my death my love,
a woman of substance
knows how dearly I worshiped her,
knows her true worth.
She will live into her nineties happy in the knowledge
she was loved for who she was - we were always one.
My Angel through my coffin explains to me
no soul is damned, when an act is selfless.
My wife and I will meet again!
So our story ends, but not before we hear a sound,
the echo of teeth that chatter. Chatter louder than ever.
It is literally
A Cold Day In Hell!
Sponsor: Justin Bordner
Contest Name: Death Shadow
Copyright © Maurice Yvonne
Iris sun fades and so does the day
whispers the carried in the silence of night glowing
Wishes floating on silver trails faraway
The image of your face will forever bounded to this world
Angels Brought you to me made a lightening
sparkling diamonds in the misting treasures gems so bright
Ice roses turns into a steaming jungle of quivering glass
Flashing in the distance, in the moon light
and all of its stars, that's where the angels dancing
A beautiful adventure picture sparklers on a winter night
A cold moon dressed in dark velvet
with a pearl milky white smile beams
Sparkling jewel crystal lights up
stars blinking silver awakening
warm invading darkness your light
My life has at last found its light and its hope
Soulful cries a wolf dressed in winter clothes
faraway over ocean waves
carries in a wind's whisper sweet music dances
A magical night that will set the spirit free
Silently breathes out a puff of magic sweetly
beauty enchants warmly etching strikes
frosted fingers cracking ice deeply echoes
Striking inside bells toll warmly skipping drumbeats
bouncing of chamber walls loving tunes
Believing in your love a dream
Which enchants music of the butterflies dance
howling clouds out steaming warm sighs fluttering warmly
I closed my eyes at the end of the road
and thought of the stars
and the reason earth spins around the sun
A co write written by Liam Mcdaid and
Anne- Lise Andresen :) - 28.12.2014 -
Copyright © liam mcdaid
Tell me that this fear is just paranoia in my mind,
we're not straining, we're not struggling,
we're not sinking, we're just fine.
I'm not perfect my dearest, but damn have I tried,
and I'll try harder but I know I'll have the same results every time.
Do you want me all the ways that I am?
With all the struggles and the tears and the clinging to your hand.
I fear your getting further and Im left on the shore to stand,
watching you in the distance with a bullet in my hand.
Tell me all this worry, its just clutter in my mind,
tell me not to worry that we're doing just fine.
Cause Im scared to run you off and I feel Im falling deep.
And Im so frightened of these thoughts that its getting hard to sleep.
All I know is that the heart wants what it desires,
because of you the match inside has turned into a fire.
And I feel the broken glass thats sticking from my skin,
Wondering if you'll remove the pain or push it back in.
My hearts frantic wondering if you feel the same,
pleading and begging for more than just a saying,
but to feel and to see that im not alone,
with being in this love thats overwhelming.
Once I told you that we didnt have a spark,
but you were lighting up and I was sitting in the dark.
And this fire, this blaze its wrapped in desire.
Im terrified to lose you, I think I might die or,
maybe disappear from all the pieces falling out,
im going crazy but when i open my mouth, nothing comes out,
and I cant explain to you why I just need to hold you close,
why every time you leave Im scared to let you go,
why these tears are building up behind my eyes,
all I know is that the heart wants what it desires
and it desires to be your wife.
So tell me in my panic, that your words are true,
tell my my dearest what I mean to you,
tell me that this paranoia is all within my mind
we're not struggling, we're not sinking tell me we're just fine
Copyright © Jay Loveless
Hydrogen to Helium
A fusion formed by gravity
A carbon-based delirium
Molecularly infinite energy
An ancient discipline known as alchemy
We're consciousness - the explosion - amorous
We dream of gold from lead and mercury
Fueled reaction in copper with phosphorus
A universal age of prosperity
Bismuth bath. Deficient of iron and zinc
Astronautic laugh – last shine of hope
Nuclear decay –enlightened way – elemental - instinct
Scientific – logical clay – gaseous isotope.
The fluoride, we drink?
Humanity on the pivotal brink
The edge, a precipice.
Lanthanides and actinides
Metals and mysteries.
Shrink down to atomic scale
Our intellect – an accelerated history
A holographic projection
Radioactive expansion
A gravitational trajectory
Precious pavonine pearl
Our planet, our world.
A place all our elements may inhabit
Terrestrially unique. Diverse and intelligent
The push of inertia
The pull of gravity
The spin of an atom
The spin of our galaxy.
The end.
(written for the periodic table of elements poetry contest) 12-12-14
Copyright © Joel Thornton
The fog is so thick I can not see the sticks, that in a wasted life,
rise off the dirty grave of the forest floor.
There is no beauty that could compare to the sight
of the thick ground clouds, that embrace my morning.
To run through the moisturous blanket into the unseen
and unknown would be a spectacular thrill.
The cool droplet of water stroking my feet, as they are released from
the tall finger grasses. tickle me kindly.
I chase the fog as its spread of mystery begins to rise
and confines back up into the sky.
I reach for the heartbeat of the fog, hoping that surrounding my skin,
with its life, it would carry me away.
I dance with it deeper into the dense woods, where it awakens the pine trees,
with its wet breath.
Higher and higher the fog rises.
I climb a welcoming oak tree,
stretching with its limbs grabbing for the clouds.
Take me away my morning fog, I want to ride this elevator to the sky,
to the heavens, take me away.
The fog disappaites and I am left with misty hands and empty eyes.
I look around clearly, seeing the crispness of nature,
basking in all her beauty
From the heights of this old oak tree,
I realize... I am lost.
Vibrant Verse Contest
Copyright © CT Duet
How would you change?
If it were all true.
Heaven and Angels..
watching over you?
Is there Paradise in
..the hereafter?
Some just don't..
think things matter.
What if Swarms of angels..
like butterflies.
Came to earth..would you realize?
That everything matters
that life's the prize.
How long will it take..
till you recognize..
What if the sun went dark.
What if it were true?
Would you change your ways?
Have a new point of view?
What if the Four horseman..
came galloping in?
Would your conscience feel clear?
Would you regret a sin?
Our toys are just toys..
It's not about money.
It's about loving each other..
and holding your honey.
It's about time..
and what we do with it.
Get up and dance..
or choose to sit.
The choice is yours.
So what will you do?
Will you change your ways?
What if it's true?
Copyright © Jennifer M.
Hot sexy beautiful awakening
Rising out from the ashes
Alone breathing silently in thoughts
an amazing dream begins to shine
I felt the sun with her gentle fingers
softly touching with her light
Stepping outside yawning, birds of all kinds
whistling in choir
Looking across the mountains
felt warm weaving love
Gently brushing softly
within a warm sweet gentle, kissing breeze
Looking down through the valley
sweeping out towards, the great Atlantic sea
So many beautiful colors in blossom
Looking towards the sky, white mother of pearl clouds
dancing softly across vision
Her color a Heavenly baby blue
At that moment in time, searching
inside wonderful thoughts
They were sweetly kissing you
far away in a distant paradise
Always and forever golden
treading these sands
To walk hand in hand with you
sweet angel of love
Warm are the footprints that treads
Softly landing on the deepest sands
Entering the heart
through the eyes of a soul
Captured in this vision
from inside out
A picture beautiful dream
sweetly smiles on you love
Strange colored skies climb northernly this night
Calling our future with wild deamons eyes
Abscure as the creatures who answer the call
Wild are the answers of the reasons and the faults
Certain as the well swept winds
Alluring in it's grasp fought negatively through single wins
I pray twords the skies and it curdles and swims
Thoughts twords the sun and it scorches my rims
Carry me far enough I can be within your sights
Stash us away and the sun will be bright
Motors may break but oceans will be light
I will stay on the coast and wait
The award I will do is make the evening a minute late
Parched is the gulf as the single minute breaks
Great is the second docks a seperate mans gate
The Earths crust slowly begins to crumble
It quivers, then quakes, it slowly opens, the rivers break
A star is born somewhere, a beautiful new star
Great is the struggle, born from the heavens a small light it makes
The new star pulls, it turns, then it feeds and it's fuel it burns
Gently it orbits following all things it understands
The new star bends it dances it stands
Tancing outwardly as creations comprehend
A continient wavers as the new star binds its brand
It feeds off of our oceans as our tides wash in
It goes just as softly forward and back
As the rays of its placement barrow up to the sun
We watch very carefully because it's damages are already done
Copyright © Courtney Courtney
Things begin turning around and very
slowly they take a nasty foreboding twist
as Hell's Dragon has not breathed yet
a deep burning fire melting red his eyes
dripping blood upon fury and destruction
pumping inside the uncontrollable fire
equal to that of a thousand steamboats
and only he sleeps in the dark dungeons.
Chained and suffering in utter Hellfire
chained in untold torment and anguish
unleashed he would burn your heart no less
in a flash—while scorching all to nothingness
fried black from the deepest ashes falling
cold silently sleeping with wings on fire and
chained to love's weakness as the dark fables say:
Do Not Call Upon This Beast—He's The Devil's Own.
Hell's Dragon stirs inside with tongues of flames
lashing with the pains of hate to strike all now
leaving hottest cinders and funeral pyres a plenty
it's now the Devil's very moment to unleash His Evil,
His Demon Dragon upon the saintly and the pure
and the precious doing their good works and all
and unsuspecting of the malevolence awaiting them.
The Devil enters afresh the earthly plane once more and
releases His Dragon to inflict harm and to upset
God's celestial equation of peace, harmony, and light—
bringing death, destruction, and retribution to all in
its flight path while breathing out the harshest and
cruelest and hottest flames of fiery perfidy in the
name of Lucifer—Himself laughing boisterously at God
all the while not knowing the coming angelic answer.
The Almighty Lord works indeed in the most mysterious
of ways and He will not let his Fallen Angel Lucifer (or
"The Devil" on Earth) have His way by murdering
innocents through His Dragon proxy only too willing to
serve His Master to bring horrible hideous death to all
of mankind who fall within its flight path and intention
to inflict the most treacherous and dastardly plan of
of unmitigated death and horror ever to be unleashed.
Continued burning flesh 2
Liam McDaid and Gary Bateman – A Collaborated Poem,
Copyright © All Rights Reserved (November 28, 2014)
(Free Verse poetic format)
The angelic answer of the Almighty Lord comes swiftly
As Archangels Michael and Gabriel with their Band of
Burning Flesh - The Devil's own
Angels enters the earthly plane to confront the Hellfire
vengeance of The Devil and His Dragon as they reap and
sow their evil upon mankind, and with a sudden determined
fury Michael does fatally smote The Devil's Dragon
while lopping its head off and sending its soul back to Hell
while Gabriel banishes the demon forces waving his wand!
With all this Lucifer knows with all due certainty that He
must return and rejoin His evil minions who lurk in the
infernal regions of the Earth, knowing that he's lost once
more to the Almighty Lord in another struggle of Good
versus Evil and has now been deprived of his most
prized pawn of death and destruction—His very own
Dragon whose blackened soul suffers now forever in Hell
And can never be reincarnated again in its bodily form!
Liam McDaid and Gary Bateman – A Collaborated Poem,
Copyright © All Rights Reserved (November 28, 2014)
(Free Verse poetic format)
Oh sky look down on this earth of gray,
Something dreadful on the horizon looms.
There is no black and no white today,
Laws exist but justice is doomed.
Morality is labeled religion,
And must be separated from state,
Whose own religion is political correctness
And determining God's fate.
Oh heaven rain down on us,
Ae are tasting your tears.
Yes we've become that bad,
Confirming your fears,
That what has been done ,
Is being done again,
Those lessons taught,
Coming to naught.
Judges and laws make it legal,
To be rid of your innocent babes,
Under a symbol of the eagle,
God's loving justice betrayed.
Racheal you cry the tears,
That now only heaven supplies,
Because ours have dried,
In the dust of our alibies.
Excuses and lies are linked,
As you and I know well,
The truth is all but extinct.
Truth is foreign to hell.
Oh heaven, look down on this world of gray.
Something dreadful is watching and looms.
Is there nothing left but to watch and pray,
While Rachael wails by the dumpster tombs?
Copyright © Robert A. Dufresne
as I stand here and gaze
into the heavens
this dark, inky sky
ahhh . . .
now I see you my love
my bright, shining Gibbous Moon
the dark cloud
moved on into the night
showing the heavens my spirituality
for we are as one
whether you are a mere Crescent Moon
timidly showing
mere tantalizing part of you
we may only guess
what is hidden
in the darkness which is you
its as if you are having wicked fun
at my expense
time gives me the taste of
your delicious and tempting Half Moon
glow of iridescence revealing
more of yourself
although it seems the more you show
the more is hidden
you are playing me an exotic dance
befitting your lofty aspirations
an enticing, though half naked smile
I stand there
wishing the nights would flow faster
as each night
slowly evolves into the next one
you know I will
be there again and again
patiently waiting
for your final unveiling
and shows me
your patient lover
you in all your majestic glory
a huge, bright and lustrous
Full Moon rising
I almost sob
Copyright © Jerry Bolton
Made my choice
I always wear
the blessed Bennedict cross
scared of the Devil himself
for my soul protection
I saw the faces twisted in agony
mouths open screaming arms out
pleading with love to be saved
inside a moving mass of pain in Hell
I walked in the burning darkness
suffering pains a zombie for my sins
a blind existence inside one shell
I had no one other than family
to call upon as friends
Seeing suffering tortured souls
what they done to me
Trusted to easily
used and stole from in my charity
Born under the wolf moon
always watching in the shadows
a mountain climber by birthright
Howling into a cold loneliness one fight
with the heavens inside at war
Brought to my knees in the all forgiving face
of God cured of cancer one miracle
I know destiny again
coming out from arising sun
I bow humble and meek
I will be stronger for living
knowing where to place my trust
Smiling always with friends
because I see now love
It is you who makes
each and every single world go around
I walk now towards your light
forgiving my past
Ready to face this big bad world again
only now I am stronger seeing hope
always praying for you love
No redemption in Hell
it just keeps getting worse
We softly whisper to each other in our cocooned womb of ours,
wishing for the world to see our colorful souls to emerge.
The calling, the urgency so great to break free
as we wrap our beautifully colorful wings around each other
hoping for one day to be set free.
Soon it will be time for us to fly because we are so needed
Down below we'll leave our essence of our wings of change
for all to see.
We know it's not understandable just yet but the Great Creator
above took our wings and blew His breath so we can fly high
like the Eagles in the sky.
We now are the Beautiful Butterfly Angels dancing across the
four winds.
We will flutter around from here to there smiling down upon you
with such amazing grace, while our wings lightly touch so tenderly
upon your hand.
We are never far from you Mama, We are in the morning dew you see on a leaf,
we are dancing from flower petal to flower petal giggling along the way,
we are in the morning sunrise you see as the birds sing their lovely chorus
to you, we are the love that we felt the whole time through.
We Are Your Beautiful Butterfly Angels For Evermore.
Copyright © Angela Roark
just once in a lifetime
you touch,
less than a touch,
maybe just maybe
once in a lifetime
you are close enough to greatness
to almost feel it
but you don't
because with greatness
true greatness
the moment is one
no one but you recognizes
it is a hug
from the person
who held up that sign
what seems now
like an eon ago.
the sign said
you could have walked away
turned a blind eye
that person
without a word
is inside your head
the voice
is clear
"it's the right thing to do"
echoes in your mind
as if your skull
were the Grand Canyon
you do it.
you sacrifice everything
and you do it.
you help
and when your deed is complete
when it is all said and done
that person hugs you
when it is all said and done
you hug that person
and for that moment
you feel less than space between you and it
and you know it is greatness
but in your humility
as quick as you think it
it is gone.
but you are changed forever more
and you know
heaven is this
no high from any other source
will ever be the same
you've just stepped up
the rungs of your ladder
and there is no crash
from this high.
you are on a new plateau
and it is higher
and it is lower
with greatness
true greatness
comes humility.
"I Do Believe"
The purpose of LIFE is to {Living In Faith Ever}
to enrich God within us
to an optimum level
so that We as Humans
can be guided by God
to fuel out brothers and sisters
with the same driving force
to connect with the living God,
to His existence and
to See the Invisible,
Believe the Incredible, and
to Receive the Impossible
to our everlasting journey
to Heaven.
Rev. Samuel Mack
Copyright 2013
Copyright © Rev. Dr. Samuel Mack OMS DD
The sweetest sounds of burning trees
A gentle stroking in the breeze
The calm has lasted past the storm
Cloudy visions, Satan's roar
Too many sights have passed my way
A time found only in the haze
The softest screams are running bare
My aching bones creak as I stare
You walk a distance towards me
The fall's eternal, can't you see?
I'm a memory in your heart
I whisper to you in the dark
The battle's started at the end
No one is coming to repent
The sinners grab their wine from prey
No judgment calling here to stay
The sport is reckless to be told
The one is laughing at his souls
It falters nowhere to be sure
The power grows forevermore
Like a spirit in the wind
I have no say in where you've been
But cross the line to come to me
And pay the price for ecstasy
You walk a distance towards me
The fall's eternal, can't you see?
I'm a memory in your heart
I whisper to you in the dark.
Copyright © John Paluszek
Flowers bloom
And flowers wilt.
Flowers blush
And flowers fade.
The eternity is only in me-
The twig that bears the flowers.
Sparrows are born
And sparrows die.
Sparrows fly
And brighten the sky.
That who nurtures sparrows is me-
A cozy make of a twig upon a twig.
The sun fades
And moon is born.
The twilight blurs
And moonlight spreads.
All the soothing moonlight beams are me-
A crisscross of unfathomed twigs.
Whether in its birth
Or in its death;
In the heart
Of its heart;
The entire beauty is none but one-
A design of mysterious twigs.
Copyright © Suyash Saxena
Here I lie beside you
My heart goes thump.thump.thump.
My soul dances inside you
Reveling in the texture of your own.
Electric and flowing
The currents of our love
Glow like neon lights
Illuminating the hope in my eyes.
Though we're not moving
I feel so incredibly alive
Invincible to my past
Untouchable by all who lack
That gentle touch of when
You lean in and brush my face
Your lips grazing my skin
Softer than a butterfly.
And then you gaze into my eyes
I fall into your depths
Twirling like the autumn leaves
Melting into your smile
Your soul reminiscent of summer.
You pull me into your arms
And for a moment I'm lost
Breathless and in awe
Staring in the face of pure exquisite love
And there you are - holding it
Glowing in the moonlight of my stare.
My heart beats - its drum pounding away
Echoing a song thats lost its words
I touch your cheek and smile
My hands cant stay away
My lips s l o w l y, draw near yours
Hovering, and then -
Part, a soft warmth against them.
My eye lids pulling shut
Dragging me into a silent heaven
I pull away - and what seemed millennia
Lasted only a moment, a second in time
But this is our love
This is what you do to me
You make me invincible and fragile
Lost forever in a beautiful reverie.
Lupita…forgive me,
For I would never sin from these
Such words that would spoil the beauty
of your existence;
But if you requested such a crime, I'd argue
for remnants of your time,
And charm you as my fatal audience.
Of these things I would cite verbally,
Would be the origin of shape, gifted upon
your figure,
Those curves that gave birth to the unpredictable
patterns of life,
Swaying the adoration of midnight flesh, into these
new testaments of woman.
How simply intoxicating is this craving?
To bear witness to chocolate unspoiled, as it lay
peacefully naked over maker's canvas;
Let it not melt away, before millions can sample its
sensuous glow.
Perhaps art can be reborn from such stillness,
While wasted labels could fade into retirement,
Convincing the almighty to revise the structure of
And acknowledge this last miracle…Lupita.
What else could be molded from this paradise, but a
Queen's thoughts and motives?
If there is nothing but truth in this crime, then I've painted
the solitude of heaven, perfectly.
Copyright © Jiril Clemons
The Soup and all the mix ~
this has given me my own home
A warm place I feel safe a Family
Many Inspired me with Love and welcome from the 1st Day
One comes to mind and what would I say ?
The beautiful Poetess Anne lise , from Norway ~
Anne Lise being sweet and responding from the start
A most important part of the soup here in many hearts
I want to say Thank-you for reading and inspiring me to write
I want to say you have a beautiful Soul God gifted a special way
Showing Love , sharing art , sincere in caring for all here
Anne lise you are truly amazing our Angel Heaven sent ~
You show such Love to others indiscriminately
you read others and respond to all with beauty
May Love surround you Always keep you warm like a Blanket Forever ~
"In Honor of Our Angel Anne Lise "
Copyright © Shanity Rain
To heaven we are called,
his glory for us all.
The meeting in the air,
to stand before his chair.
So many of us are shown,
the greatness of his throne.
We will praise our loving lord,
forever in him we are restored.
Before the sea of glass,
his overcomers did outlast.
We see our savior crowned,
the trump of God to sound.
From the midst of us he came,
the lamb of God was slain.
To take the book thereof,
from his fathers hand with love.
So glorious for us to be,
his kingdom forever is ours to see.
Copyright © john aaron green
If heaven permits
I will be a robin
Up on a sunlit branch of a tree
Gazing at the far-off light
That flourishes out on the vanilla sky
I will sing
From June to the merry month of May
Every flat
Every sharp
Every note of poetic symphony
That glitters ceaselessly
I will fly
Rough and tough
Beyond ferns and herbs
At odds with
The whirling wind
That might spoil my beauty
And yes
I will soar
Steeper than the milky way
As long as the world breathes
Until heaven
Forbids me
Author's Note and Inspiration.
- Free Verse Introspection International Poetry Contest
Contest Winner- Honorable Mention(4th place)
March 15, 2008
Contest Sponsor: Deborah Simpson-Author of the Chronicles of a Sage: Spiritual Revelations
via Canto.
- The Celebrating You International Poetry Contest
Contest winner- 1st place
March 15, 2008
Sponsored by Kristine Reynolds
Copyright © cayetano young
It has been almost three years
since to heaven you did fly
We miss the beauty of your soul
now you share it with the sky...
Heaven now knows the warmth of your heart
So bright you put the stars to shame
the glow of Springtime's sun
will never be the same...
Our son has the strength of your soul
the passion of your heart with much to share
in his eyes your majesty of the cosmos
like you a love of animals with much to spare...
My love add your wonder to the stars
enhance the blue of the midday sky
we miss the unequaled shining light
and the tenderness in your eyes...
Soar all the way to heaven my lady
for eternal love has set you free
I await here among the living
for you to greet me in heaven splendidly..
~ ~
Copyright © Ken Carroll
Silent midnight, crescent moon overhead
Molten silver shimmered on dewy grass
Tender jasmine and vibrant marigold
Danced with the gentle breeze
As softly it caressed my sleepy cheeks
Resting on his warm loving shoulder
By Tahera Mannan
For Constance's " Six Lines Of Poetry, Please" contest
Copyright © Tahera Mannan
Enter a storybook tale
Where I can be
The heroine you hail
Lucid dreams of soft reflection
A touch heated with lust and desired protection
A breathe a gasp as we succeed
Join the fairytale with me
Valiant night within dark eyes
the right movement and I make them shine
like moonlight on the steamy hot spring
care to follow for a little dip with me
Trailing like the water at my fingertips
Grasp me around my hips
As close as the breeze on my skin
Whisper lies as I let you in
Lips mumbling up my thighs
bare heart exposed to the sky
fire burning in my veins
Am I a mistress of this lust or simply a slave
Trembling with desire
Take me till we've lost count of the hours
enter this storybook tale
Where I can be the heroine you hail


text:
Nice Posada in the center of Arraial, little English spoken but extremely friendly and helpful. Rooms are comfortable and all with an hammock on the patio, looking towards the swimming pool. Breakfast is very nice and they also serve afternoon tea. Definitely a place I would go back to.
What is Certificate of Excellence?
TripAdvisor awards a Certificate of Excellence to accommodations, attractions and restaurants that consistently earn great reviews from travelers.


text:
- Colors
- Detail Images
Sleek and sexy safety.
Slip on the Giro Women's Sheer Helmet the next time you want to look good and stay safe at the ski resort. In-mold construction combines a tough polycarbonate shell with an impact-absorbing liner for an ideal blend of safety and comfort. In Form adjustability utilizes a glove-friendly knob to provide a secure fit. Use the Thermostat Control to close or open the Super Cool vents to meet the riding conditions for the day. Giro audio compatibility lets you slide Giro audio systems inside the ear flaps for fun times in the park.
- In-mold construction
- Women-specific fit
- In Form fit system
- Vertical tuning
- Thermostat Control adjustable vents
- Super Cool vents
- Stack ventilation
- Compatible with Giro audio systems and goggles


text:
KHS Bicycles Inc. manufactures full lines of mountain, road and touring bicycles as well as comfort tandems and cruisers.
Phat Cycles builds a full range of classic, lightweight and specialty cruisers, as well as tandems and kids' bikes.
Retrospec bicycles are high quality but affordable fixed-gear bicycle whose incredible riding experience speaks for itself.
3G Bikes is committed to very high quality from design, to concept, to final product and are masterfully crafted.
We are a family owned and operated full-service bicycle shop offering great sales and reliable repair and maintenance to bicycle enthusiasts for over 25 years.


text:
Homeland Security
Mr. Falkenrath talked about strategies to ensure homeland security, challenges to instituting effective security policies, and preparing for potential catastrophic terrorist attacks. Following his remarks he answered questions from the audience.
People in this video
- Richard A. Falkenrath Senior Director White House Office of Homeland Security->Policy and Plans
- Philip D. Zelikow Director University of Virginia->Miller Center of Public Affairs
Hosting Organization
Related Video
Foreign Policy Challenges in the Post-Cold War World
Panelists spoke about U.S. foreign policy since the fall of the Berlin Wall. Among the topics they addressed were…
Statecraft of President George H. W. Bush
Philip Zelikow chaired a discussion of the statecraft of President George H.W. Bush. They responded to questions…
The War on Terror
The panelists talked about the war on terrorism and media coverage. Following prepared remarks, they responded to…
Terrorism Risk Insurance
Mr. Falkenrath talked about terrorism risk insurance, the threat posed by terrorism, and the role of the insurance…


text:
Pathology and Laboratory Medicine's 2nd Annual Toy Drive. Help us raise a mountain of toys by buying a new, unwrapped toy. Or, if you do not have time to pick up a toy, you can drop off cash donations to Cheryl Campbell in the Main PaLM Office, DSB 4044 and a gift will be purchased on y our behalf.
The Department of Pathology and Laboratory Medicine offers undergraduate, graduate, postdoctoral, and postgraduate programs.
Zia A. Khan Our research focuses on vascular repair and homeostasis with emphasis on the mechanisms of vascular stem cell differentiation and postnatal blood vessel formation.
James Roos I am currently working with the Motor Vehicle Safety Research Team (MOVES).
Pathology and Laboratory Medicine is the medical specialty concerned with the study of the nature and causes of diseases.
Our faculty continue to strive in teaching, research, and clinical service, the pillars of academic medicine.


text:
I have always had prescription sunglasses, but they have only been simply tinted until I recently got actual polarized sunglasses.
Right away, I noticed a lot of quirks with them, but I have never heard anyone talk about these quirks, despite millions of people wearing polarized sunglasses. I did a quick search online and some of my observations are true, and some I couldn't find anything about:
LCD screens disappear--I guess this is normal because of the vertical something-rather in the lenses. But it's really annoying. I either have to turn my head, or take my sun glasses off when using a digital camera or laptop outside.
Car windows have spots if they are tinted--and if I turn my head, I can't see through car windows at all! I couldn't find anything about this online.
I can see through yellow clothes! No joke. Yesterday, the attractive neighbor lady came outside so our babies could play together and she was wearing a yellow shirt with nothing under it and I could see through it perfectly as though she had nothing on. I took my sunglasses off and it looked like a normal shirt. I put my sunglasses back on and I could see through it again. My wife, who has just tinted sunglasses, didn't notice a thing, so I thought I was just crazy. But, I looked it up, and polarized sunglasses have something green in them to filter yellow light, thus I could see through her yellow shirt as though she wasn't wearing one.
How come I have never heard about this stuff? Clearly other FOOsters have polarized sunglasses--what other quirks are there? I also read to be extra careful in the snow with polarized lenses since it could create a hazard. What?


text:
ARLINGTON, Texas (AP) — Suspended Rangers slugger Nelson Cruz is heading home Wednesday to the Dominican Republic, where he will work out before returning to Texas later this month.
General manager Jon Daniels said Cruz will spend about 12 days in the Dominican, where the All-Star right fielder has a home gym and the team has a complex he will visit.
MATT HARRISON: Rangers shut down lefty for season
Cruz was suspended for the final 50 games of the regular season in Major League Baseball's investigation into a Florida clinic accused of distributing banned performance-enhancing drugs. He was one of 13 MLB players disciplined last week.
Daniels said Tuesday that there has been no decision made about Cruz playing in the postseason if the AL West-leading Rangers make the playoffs for the fourth season in a row.
OUT OF BASEBALL AGAIN: Manny Ramirez released by Texas
"Our goal right now is just to, as it always is, keep all of our options open," Daniels said. "So we want to do what we can to keep him in as good as shape as possible, and as good of baseball shape as possible. First of all, we've got to get there."
Cruz, the 2011 AL championship series MVP who is eligible for free agency after this season, still leads the Rangers with 27 home runs and 76 RBIs more than a week after playing his last game.
LOST SEASONS: Where did it all go wrong?
Daniels said many different factors would determine if Cruz would be an option for the Rangers if they make the playoffs.
"What kind of shape he's in, how's the team playing, how's the team gelling, how our other guys are performing," Daniels said. "Those are the things we'll have to consider. We're not there yet."
Since all of the team's minor league clubs will be done playing by the end of September, the only real option to simulate any sort of real game experience for Cruz then will probably be the instructional league.
The Rangers last week acquired Alex Rios, working out a deal with the Chicago White Sox after first putting in a waiver claim on the right fielder.
On the day MLB announced the suspensions, Cruz apologized to his teammates in the clubhouse before a game at the Los Angeles Angels.
Cruz hasn't spoken publicly since then, but said in a statement that a gastrointestinal infection he had from November 2011 through January 2012 wasn't properly diagnosed. He said he lost 40 pounds before getting proper treatment and just weeks before spring training in 2012 "made an error in judgment that I deeply regret." He provided no other specifics, including what he might have taken.
Daniels said he spoke with Cruz on Tuesday, but that the only subject of their conversation was about the upcoming plan.
Cruz has been in touch with the Rangers conditioning staff. Daniels said they will determine the next steps for Cruz when he gets back from his desired trip home.
"We're comfortable knowing between our facility and his own facility he can get the work in down there," Daniels said. "He's pretty much good with whatever we ask him to do."
Copyright 2013 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


text:
By: Adam Gretz
Canucks defenseman Aaron Rome was ejected during the second period of his team's 4-3 loss in Anaheim on Friday night. After a brief period of wondering whether or not he would face any additional punishment from the NHL for his hit on Ducks forward Devante Smith-Pelly, Jim Jamieson of the Vancouver Province reports on Saturday that Rome will not face any additional punishment from the NHL.
Jamieson writes that after reviewing the play Shanahan determined that the punishment handed out during the game was enough. That punishment, of course, was a five-minute major for elbowing and a game misconduct, all of which helped lead to a pair of Anaheim power play goals.
Even though the hit was certainly debatable from a discipline point of view, the fact Rome escaped any additional punishment is somewhat interesting given his banishment during the Stanley Cup Finals for a hit on Boston's Nathan Horton. Whether it's fair or not, Shanahan seems to have put a strong emphasis on a player's history when deciding whether or not to suspend players, as well as the length of the suspension when one is handed out.
Click Here For More NHL Discipline News
For more hockey news, rumors and analysis, follow @EyeOnHockey and @agretz on Twitter.


text:
Are you Elena Succurro?Claim your profile
Publications (51)207.55 Total impact
Article: One-hour post-load hyperglycemia is a stronger predictor of type 2 diabetes than impaired fasting glucose[Show abstract] [Hide abstract]
ABSTRACT: Subjects with normal glucose tolerance but 1-h post-load glucose ≥155 mg/dl (NGT-1h-high) exhibit an intermediate cardio-metabolic risk profile between individuals with NGT and impaired glucose tolerance (IGT). To evaluate whether NGT-1h-high subjects have different cardio-metabolic characteristics and an increased risk of type 2 diabetes as compared to individuals with isolated impaired fasting glucose (IFG). A cross-sectional analysis was performed on 595 non-diabetic subjects who underwent an oral glucose tolerance test and an euglycemic hyperinsulinemic clamp. In addition, a longitudinal analysis was performed on 392 individuals, who were reexamined after a follow-up of 5.2±0.9 years. Ambulatory care. Insulin sensitivity, beta-cell function, risk of developing diabetes. Subjects with NGT-1h-high have a significant reduction of peripheral insulin sensitivity and beta-cell function, assessed by the disposition index, as compared to either NGT-1h-low or IFG individuals, but not as compared to IGT. Among the 392 subjects studied in the longitudinal analysis the incidence rate of type 2 diabetes over the follow-up period was 2.9, 16.7, 12.5, and 31.4% for subjects with NGT-1h-low, NGT-1h-high, IFG, and IGT, respectively. In a Cox proportional hazard regression analysis the risk of developing diabetes for NGT 1h-high subjects was 4.02 (95%CI 1.06-15.26); an even higher risk (6.67 [95%CI 2.09-21.24]) was observed in subjects with IGT, but not in the isolated IFG group (1.91 [95%CI 0.44-8.29]). NGT-1h-high subjects exhibit a higher risk of developing diabetes than those with IFG or NGT-1h-low, likely due to decreased insulin sensitivity and beta-cell function.The Journal of Clinical Endocrinology and Metabolism 08/2015; 100(10):jc20152573. DOI:10.1210/jc.2015-2573 · 6.21 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: IntroductionInsulin glargine is a human insulin analog produced with recombinant DNA technology, administered once daily as a basal source of insulin in patients with type 1 or type 2 diabetes mellitus. The addition of two basic amino acids (arginine) to the B-chain and the switching of asparagine with glycine in position A21 in the insulin molecule determines a shift of the isoelectric point from a pH of 5.4 to 6.7. Therefore, insulin glargine precipitates at physiological pH in subcutaneous tissue after injection, delaying the absorption. Moreover, the addition of zinc to stabilize interhexamer contacts prolongs the activity of this analog. Studies in healthy volunteers have indicated that insulin glargine has a smooth peak less profile of action that is required from a basal insulin injected once daily [1].Several side effects have been reported during the treatment with insulin glargine, such as hypoglycemia and irritation at the injection site. These effects are common and the irr ...Acta Diabetologica 01/2015; 52(4). DOI:10.1007/s00592-014-0707-7 · 2.40 Impact Factor
Article: Association between Noninvasive Fibrosis Markers and Cardio-Vascular Organ Damage among Adults with Hepatic Steatosis[Show abstract] [Hide abstract]
ABSTRACT: Evidence suggests that advanced fibrosis, as determined by the noninvasive NAFLD fibrosis score (NFS), is a predictor of cardiovascular mortality in individuals with ultrasonography-diagnosed NAFLD. Whether the severity of histology (i.e., fibrosis stage) is associated with more pronounced cardiovascular organ damage is unsettled. In this study, we analyzed the clinical utility of NFS in assessing increased carotid intima-media thickness (cIMT), and left ventricular mass index (LVMI). In this cross-sectional study NFS, cIMT and LVMI were assessed in 400 individuals with ultrasonography-diagnosed steatosis. As compared with individuals at low probability of liver fibrosis, individuals both at high and at intermediate probability of fibrosis showed an unfavorable cardio-metabolic risk profile having significantly higher values of waist circumference, insulin resistance, high sensitivity C-reactive protein (hsCRP), fibrinogen, cIMT, and LVMI, and lower insulin-like growth factor-1 (IGF-1) levels. The differences in cIMT and LVMI remained significant after adjustment for smoking and metabolic syndrome. In a logistic regression model adjusted for age, gender, smoking, and diagnosis of metabolic syndrome, individuals at high probability of fibrosis had a 3.9-fold increased risk of vascular atherosclerosis, defined as cIMT>0.9 mm, (OR 3.95, 95% CI 1.12-13.87) as compared with individuals at low probability of fibrosis. Individuals at high probability of fibrosis had a 3.5-fold increased risk of left ventricular hypertrophy (LVH) (OR 3.55, 95% CI 1.22-10.34) as compared with individuals at low probability of fibrosis. In conclusion, advanced fibrosis, determined by noninvasive fibrosis markers, is associated with cardiovascular organ damage independent of other known factors.PLoS ONE 08/2014; 9(8):e104941. DOI:10.1371/journal.pone.0104941 · 3.23 Impact Factor
Article: Elevated 1-h post-load plasma glucose levels in subjects with normal glucose tolerance are associated with unfavorable inflammatory profile[Show abstract] [Hide abstract]
ABSTRACT: Glucose tolerant subjects with 1-h post-load glucose ≥155 mg/dl (NGT-1 h-high) are at increased risk for type 2 diabetes (T2DM). Prospective studies showed that chronic subclinical inflammation is a predictor of T2DM. In this study, we aimed to evaluate the inflammatory profile in NGT-1 h-high subjects as compared with individuals with 1-h post-load glucose <155 mg/dl (NGT-1 h-low). To this end, an oral glucose tolerance tests (OGTT) were performed in 1,099 nondiabetic whites. Cardio-metabolic risk factors including high-sensitivity C-reactive protein (hsCRP), erythrocyte sedimentation rate (ESR), fibrinogen, and complement C3 (C3) were determined. Of the 1,099 subjects examined, 497 had NGT-1 h-low, 154 had NGT-1 h-high, 158 had isolated impaired fasting glucose (IFG), and 290 had impaired glucose tolerance (IGT). As compared with NGT-1 h-low, NGT-1 h-high and IGT subjects exhibited significantly higher hsCRP, ESR, fibrinogen, and C3 levels. Notably, hsCRP, ESR, and C3 were also significantly higher as compared with IFG individuals. In a logistic regression analysis adjusted for age and gender, NGT-1 h-high and IGT subjects had a 1.8-fold increased risk of having the highest value of the Inflammatory Score. These data suggest that a value of a 1-h OGTT glucose ≥155 mg/dl may be helpful to identify a subset of normal glucose tolerance individuals at risk for chronic subclinical inflammation, a predictor of T2DM, and cardiovascular diseases.Acta Diabetologica 03/2014; 51(6). DOI:10.1007/s00592-013-0539-x · 2.40 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Since the skin represents a common site of adverse drug reactions, few data are reported at this time regarding the development of skin rash during the treatment with antidiabetic drugs. We report a 29-year old woman that developed a facial skin rash during the treatment with metformin. Clinical and laboratory findings excluded the presence of systemic diseases, but several diagnosis and many drugs were administered without clinical improvement. The self-dismission of metformin induced an improvement of symptoms, while the re-challenge documented an impairments of skin rash. The Naranjo probability scale suggested a probable association between metformin and skin rash and metformin was definitively dismissed. We report for the first time a non vasculitis facial skin manifestation related to metformin in a young woman. However, this case may emphasizes the need to consider the ADRs as a differential diagnosis in order to reduce medical errors and the related medical costs.BMC pharmacology & toxicology 02/2014; 15(1):3. DOI:10.1186/2050-6511-15-3
- [Show abstract] [Hide abstract]
ABSTRACT: Thyroid angiosarcoma is an uncommon thyroid carcinoma and its incidence is the highest in the European Alpine regions. Thyroid angiosarcoma is also a very aggressive tumor that can rapidly spread to the cervical lymph nodes, lungs, and brain or can metastasize to the duodenum, small boewl, and large bowel. Although it is histologically well defined, clear-cut separation between the angiosarcoma and anaplastic thyroid carcinoma is difficult. A 49-year-old Caucasian female patient, born and resident in Southern Italy (Calabria), in an iodine-sufficient area, was admitted to the Surgery Department because she presented with a painless mass in the anterior region of neck enlarged rapidly in the last three months. After total thyroidectomy and right cervical lymphadenectomy, postoperative histological examination revealed the presence of a thyroid angiosarcoma with positive staining for CD31 and for both Factor VIII-related antigen and Vimentin and only partially positive for staining pancytokeratin and presence of metastasis in cervical, supraclavicular, mediastinal and paratracheal lymph nodes. The patient started adjuvant chemotherapy and she was treated for 6 cycles with Doxorubicin, Dacarbazine, Ifosfamide, and Mesna (MAID). After 22 months from surgery, the patient is still alive without both local and systemic recurrence of the disease.Case Reports in Oncological Medicine 11/2013; 2013:901246. DOI:10.1155/2013/901246
Article: Decreased Insulin Clearance in Individuals with Elevated 1-h Post-Load Plasma Glucose Levels[Show abstract] [Hide abstract]
ABSTRACT: Reduced insulin clearance has been shown to predict the development of type 2 diabetes. Recently, it has been suggested that plasma glucose concentrations ≥8.6 mmol/l (155 mg/dl) at 1 h during an oral glucose tolerance test (OGTT) can identify individuals at high risk for type 2 diabetes among those who have normal glucose tolerance (NGT 1 h-high). The aim of this study was to examine whether NGT 1 h-high have a decrease in insulin clearance, as compared with NGT individuals with 1-h post-load glucose <8.6 mmol/l (l (155 mg/dl, NGT 1 h-low). To this end, 438 non-diabetic White individuals were subjected to OGTT and euglycemic-hyperinsulinemic clamp to evaluate insulin clearance and insulin sensitivity. As compared with NGT 1 h-low individuals, NGT 1 h-high had significantly higher 1-h and 2-h post-load plasma glucose and 2-h insulin levels as well as higher fasting glucose and insulin levels. NGT 1 h-high exhibited also a significant decrease in both insulin sensitivity (P<0.0001) and insulin clearance (P = 0.006) after adjusting for age, gender, adiposity measures, and insulin sensitivity. The differences in insulin clearance remained significant after adjustment for fasting glucose (P = 0.02) in addition to gender, age, and BMI. In univariate analyses adjusted for gender and age, insulin clearance was inversely correlated with body weight, body mass index, waist, fat mass, 1-h and 2-h post-load glucose levels, fasting, 1-h and 2-h post-load insulin levels, and insulin-stimulated glucose disposal. In conclusion, our data show that NGT 1 h-high have a reduction in insulin clearance as compared with NGT 1 h-low individuals; this suggests that impaired insulin clearance may contribute to sustained fasting and post-meal hyperinsulinemia.PLoS ONE 10/2013; 8(10):e77440. DOI:10.1371/journal.pone.0077440 · 3.23 Impact Factor
Article: Differences in insulin clearance between metabolically healthy and unhealthy obese subjects[Show abstract] [Hide abstract]
ABSTRACT: Metabolically healthy obese (MHO) are relatively insulin sensitive and have a favorable cardio-metabolic risk profile compared with metabolically abnormal obese (MAO). To evaluate whether MAO individuals have a decreased insulin clearance compared with MHO individuals, 49 MHO, 147 MAO, and 172 non-obese individuals were analyzed in this cross-sectional study. Insulin clearance and insulin sensitivity were assessed through euglycemic hyperinsulinemic clamp. MHO subjects exhibited significant lower triglycerides, total cholesterol, 2-h post-challenge glucose, fasting and 2-h post-challenge insulin, steady-state plasma insulin, alanine aminotransferase, aspartate aminotransferase, and gamma-glutamyltransferase as compared with MAO individuals. Disposition index was higher in MHO subjects as compared with MAO individuals after adjusting for gender and age (P = 0.04). Insulin clearance was significantly lower in MAO individuals as compared with MHO and non-obese individuals. The difference between the two obese subgroups remained significant after adjusting for gender, age, waist circumference, fat mass, and insulin-stimulated glucose disposal (P = 0.03). The hepatic insulin extraction (C-peptide/insulin) in the fasting state was significantly higher in MHO subjects as compared with MAO individuals (P < 0.0001). In univariate analysis adjusted for gender and age, insulin clearance was correlated with hepatic insulin extraction (P = 0.01). In conclusion, insulin clearance differs among obese subjects with different metabolic phenotypes. Impaired insulin clearance may contribute to sustained fasting and post-meal hyperinsulinemia observed in MAO individuals.Acta Diabetologica 08/2013; 51(2). DOI:10.1007/s00592-013-0511-9 · 2.40 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: The aim of this study was to investigate whether insulin clearance is independently associated with carotid artery intima-media thickness (IMT), a well-recognized index of vascular damage. 361 Non-diabetic Caucasian subjects were subjected to euglycemic hyperinsulinemic clamp to assess insulin sensitivity, and insulin clearance. IMT of the common carotid was measured by ultrasonography. Among the study group, 270 subjects had normal glucose tolerance, 33 had impaired fasting glucose, and 58 had impaired glucose tolerance. Univariate correlations showed that age, BMI, waist, blood pressure, triglycerides, fasting and 2-h post-load glucose and insulin levels were positively correlated with carotid IMT whereas HDL, insulin clearance, and insulin-stimulated glucose disposal were negatively correlated with IMT. A multivariate regression analysis in a model including, in addition to insulin clearance, age, gender, BMI, waist, blood pressure, triglycerides, HDL, fasting and 2-h post-load glucose, insulin-stimulated glucose disposal, fasting and 2-h post-load insulin showed that the traits independently associated with carotid IMT were BMI (β = 0.42, P < 0.0001), insulin clearance (β = -0.29, P < 0.0001), age (β = 0.19, P < 0.0001), waist (β = 0.18, P = 0.01), diastolic blood pressure (β = 0.17, P = 0.01), and 2-h post-load glucose (β = 0.12, P = 0.03). These factors explained 26% of the variance in carotid IMT. Subjects in the lowest tertile of insulin clearance had a 4.06-fold higher odds of having vascular damage (IMT > 0.9 mm) as compared with those in the highest tertile (OR 4.06, 95%CI 1.15-13.24). Insulin clearance is independently associated with carotid IMT in adult non-diabetic subjects. Individuals with lower levels of insulin clearance have a higher odds of vascular damage.Atherosclerosis 08/2013; 229(2):453-8. DOI:10.1016/j.atherosclerosis.2013.06.011 · 3.99 Impact Factor
Article: Increased carotid intima-media thickness in the physiologic range is associated with impaired postprandial glucose metabolism, insulin resistance and beta cell dysfunction[Show abstract] [Hide abstract]
ABSTRACT: Carotid Intima-Media Thickness (C-IMT) is a reliable predictor of cardiovascular events. We examined if increased C-IMT was associated with defects in glucose metabolism in non-diabetic subjects independently of age. In 366 Caucasian non-diabetic subjects of the CARAMERIS study, we measured glucose response during a 75 g-Oral Glucose Tolerance Test (OGTT), insulin sensitivity index (ISI, by Matsuda Index), Liver Insulin Resistance Index (Liver-IR), insulin secretion by ΔAUC Ins0-120/Glu0-120 (ΔI/ΔG) and beta cell function (Disposition Index, DI). Subjects were divided in two groups according to the median age (AGE1 ≤ 45 y; AGE2 > 45 y). Only 5 subjects in AGE1 and 32 in AGE2 had C-IMT > 0.9 mm. Compared to AGE1, AGE2 had a worse cardio-metabolic profile, increased cholesterol, glucose and insulin concentrations, blood pressure and C-IMT. Both ΔI/ΔG ratio and DI were significantly reduced in AGE2. By considering tertiles of C-IMT in each AGE group (G1-G3, where G3 comprised the highest C-IMT), we found that G3 showed increased OGTT glucose profiles and Liver IR, decreased ISI and DI, compared to G1 in each AGE group. Increased C-IMT, but within normal ranges, is associated independently of age with altered postprandial glucose profile, increased peripheral and hepatic insulin resistance, decreased b-cell function. C-IMT measurement should become a routine analysis even in younger subjects to predict the risk of cardio-metabolic disease.Atherosclerosis 08/2013; 229(2):277-81. DOI:10.1016/j.atherosclerosis.2013.05.028 · 3.99 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Background and aims: The A1C diagnostic criterion for identifying individuals at increased risk for diabetes, introduced by the American Diabetes Association in 2010, was not defined on the basis of the principal pathophysiological abnormalities responsible for the development and progression of type 2 diabetes; we therefore wished to gain a deeper insight into the metabolic abnormalities characterizing the group of at risk individuals with an A1C value of 5.7-6.4%. Methods and results: As many as 338 non-diabetic offspring of type 2 diabetic patients were consecutively recruited. Insulin secretion was assessed using both indexes derived from oral glucose tolerance test (OGTT), and intravenous glucose tolerance test (IVGTT). Insulin sensitivity was measured by hyperinsulinemic euglycemic clamp. As compared with subjects with A1C <5.7%, individuals with A1C of 5.7-6.4% exhibited lower insulin sensitivity after adjusting for age, gender and body mass index (BMI). Insulin secretion estimated from the OGTT, did not differ between the two groups. By contrast, as compared with subjects with A1C <5.7%, the acute insulin response (AIR) during an IVGTT and both IVGTT-derived and OGTT-derived disposition indexes were reduced in individuals with A1C of 5.7-6.4% after adjusting for age, gender and BMI. As A1C increased to ≥ 5.7%, a sharp decrease in insulin sensitivity and β-cell function, measured as disposition index, was observed. Conclusions: Caucasian individuals with A1C ≥ 5.7% exhibit both core pathophysiological defects of type 2 diabetes i.e. insulin resistance and β-cell dysfunction.Nutrition, metabolism, and cardiovascular diseases: NMCD 04/2013; 24(1). DOI:10.1016/j.numecd.2013.01.011 · 3.32 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Background and Aims Normoglucosetolerants (NGT) are considered at low risk, even if a 1-hour post-load glucose (PLG) value ≥155mg/dl identifies NGT at high-risk for type-2 diabetes (T2) and subclinical organ damage. Specific dietary factors may affect insulin sensitivity and the risk of T2D. However, it's unknown whether dietary components affect 1-h PLG in NGT hypertensives. Methods and Results We selected 188 subjects (94 NGT<155 and 94 NGT>155), well matched for age, gender and BMI. Insulin sensitivity was evaluated using Matsuda index. Dietary intake was quantified by a semiquantitative food frequency questionnaire validated in the EPIC study. NGT>155 had significantly reduced insulin sensitivity (40.3+19.8 vs 73.3+28.8; P<0.0001). With the exclusion of total calories, lipids, alcohol and fiber consumption we observed a significant difference, between groups, in starch (214.1+52.4 vs 268.8+71.8 g; P<0.0001), saturated (27.4+8.7 vs 24.1+8.5 g; P=0.009), monounsaturated (45.5+8.9 vs 48.8+10.7 g; P=0.023) and polyunsaturated fatty acids (FA) (14.5+4.0 vs 16.8+4.7 g; P<0.0001), fructose (14.5+5.3 vs 11.2+4.8 g; P<0.0001), and oligosaccharides (103.2+26.6g vs 89.9+29.2g; P=0.001) consumption. In the whole population, starch was the major predictor of 1-h PLG, explaining 23.2% of variation (P<0.0001). In NGT<155, fructose was the strongest predictor, accounting for 15.4% of variation; BMI, gender and polyunsaturated FA, added another 6.6%, 3.6% and 3.2%, respectively. In NGT>155, saturated and polyunsaturated FA were retained as the major predictors of 1-h PLG, explaining 18.2% and 11.4% of variation. Conclusions Present data demonstrate that dietary patterns affect 1-h PLG, remarking the importance of both quantitative and qualitative composition of diet.Nutrition, metabolism, and cardiovascular diseases: NMCD 01/2013; 24(5). DOI:10.1016/j.numecd.2013.11.005 · 3.32 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Hyperglycaemia in patients with Acute Coronary Syndrome (ACS)is common, and is an independent predictor of mortality and morbidity in patients both with and without diabetes mellitus. Hyperglycaemia may be a marker of pre-existing diabetes or glucose intolerance or may also represent a transient stress response mediated through the autonomic nervous system with release of adrenal corticosteroids and catecholamines. Several evidences suggest that an intensive control of hyperglycaemia results in a significant improvement of the adverse outcomes in the short and long term. In fact, an intensive metabolic treatment can counteract the negative effects of hyperglycaemia. However, the main difficulty to intensive glucose control in patients with ACS remains hypoglycaemia that is associated with an increased risk of mortality and myocardial re-infarction. No definitive data are available about the beneficial effects of insulin intensive treatment. Therefore, randomized multicenter clinical trials will be needed to definitively establish whether intensive glucose control will reduce the associated increased mortality rate and higher rates of complications in hospitalized ACS patients with hyperglycaemia. Clin Ter 2012; 163(5):403-409.La Clinica terapeutica 09/2012; 163(5):403-409. · 0.33 Impact Factor
Article: A Functional Variant of the Dimethylarginine Dimethylaminohydrolase-2 Gene Is Associated with Insulin Sensitivity[Show abstract] [Hide abstract]
ABSTRACT: Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of endothelial nitric oxide synthase, which was associated with insulin resistance. Dimethylarginine dimethylaminohydrolase (DDAH) is the major determinant of plasma ADMA. Examining data from the DIAGRAM+ (Diabetes Genetics Replication And Meta-analysis), we identified a variant (rs9267551) in the DDAH2 gene nominally associated with type 2 diabetes (P = 3 × 10(-5)). initially, we assessed the functional impact of rs9267551 in human endothelial cells (HUVECs), observing that the G allele had a lower transcriptional activity resulting in reduced expression of DDAH2 and decreased NO production in primary HUVECs naturally carrying it. We then proceeded to investigate whether this variant is associated with insulin sensitivity in vivo. To this end, two cohorts of nondiabetic subjects of European ancestry were studied. In sample 1 (n = 958) insulin sensitivity was determined by the insulin sensitivity index (ISI), while in sample 2 (n = 527) it was measured with a euglycemic-hyperinsulinemic clamp. In sample 1, carriers of the GG genotype had lower ISI than carriers of the C allele (67 ± 33 vs.79 ± 44; P = 0.003 after adjusting for age, gender, and BMI). ADMA levels were higher in subjects carrying the GG genotype than in carriers of the C allele (0.68 ± 0.14 vs. 0.57 ± 0.14 µmol/l; P = 0.04). In sample 2, glucose disposal was lower in GG carriers as compared with C carriers (9.3 ± 4.1 vs. 11.0 ± 4.2 mg × Kg(-1) free fat mass × min(-1); P = 0.009). A functional polymorphism of the DDAH2 gene may confer increased risk for type 2 diabetes by affecting insulin sensitivity throughout increased ADMA levels.PLoS ONE 04/2012; 7(4):e36224. DOI:10.1371/journal.pone.0036224 · 3.23 Impact Factor
Article: Cardiometabolic Risk Profiles and Carotid Atherosclerosis in Individuals With Prediabetes Identified by Fasting Glucose, Postchallenge Glucose, and Hemoglobin A1c Criteria[Show abstract] [Hide abstract]
ABSTRACT: We evaluated whether cardiometabolic risk profiles differ for subjects identified as having prediabetes by A1C, fasting glucose (FPG), or 2-h postchallenge glucose (2-PG) criteria. Atherosclerosis risk factors, oral glucose tolerance test, and ultrasound measurement of carotid intima-media thickness (IMT) were analyzed in 780 nondiabetic individuals. Poor agreement existed for A1C and FPG criteria for identification of subjects with prediabetes (κ coefficient = 0.332). No differences in cardiometabolic risk profiles were observed among the three groups of individuals with prediabetes by A1C only, FPG only, and both A1C and FPG. Poor agreement also existed for A1C and 2-PG criteria for identification of individuals with prediabetes (κ coefficient = 0.299). No significant differences in cardiometabolic risk factors were observed between IGT-only and individuals with prediabetes by A1C and 2-PG. Compared with subjects with prediabetes identified by A1C only, IGT-only individuals exhibited a worse cardiometabolic risk profile, with significantly higher systolic blood pressure, pulse pressure, 2-h postchallenge insulin, triglycerides, high-sensitivity C-reactive protein, and carotid IMT, and lower HDL cholesterol levels and insulin sensitivity. These results suggest that considerable discordance between A1C, FPG, and 2-PG exists for the identification of individuals with prediabetes and that the cardiometabolic risk profile of these individuals varies by metabolic parameter, with 2-PG showing the stronger association with cardiometabolic risk factors and subclinical atherosclerosis than FPG or A1C.Diabetes care 03/2012; 35(5):1144-9. DOI:10.2337/dc11-2032 · 8.42 Impact Factor
Article: Insulin Sensitivity, -Cell Function, and Incretin Effect in Individuals With Elevated 1-Hour Postload Plasma Glucose Levels[Show abstract] [Hide abstract]
ABSTRACT: Individuals with normal glucose tolerance (NGT), whose 1-h postload plasma glucose is ≥155 mg/dL (NGT 1h-high), have an increased risk of type 2 diabetes. The purpose of this study was to characterize their metabolic phenotype. A total of 305 nondiabetic offspring of type 2 diabetic patients was consecutively recruited. Insulin secretion was assessed using both indexes derived from oral glucose tolerance test (OGTT) and intravenous glucose tolerance test (IVGTT). Insulin sensitivity was measured by hyperinsulinemic-euglycemic clamp. Compared with individuals with a 1-h postload plasma glucose <155 mg/dL (NGT 1h-low), NGT 1h-high individuals exhibited lower insulin sensitivity after adjustment for age, sex, and BMI. Insulin secretion estimated from the OGTT did not differ between the two groups of individuals. By contrast, compared with NGT 1h-low individuals, the acute insulin response during an IVGTT and the disposition index were significantly reduced in NGT 1h-high individuals after adjustment for age, sex, and BMI. Incretin effect, estimated as the ratio between total insulin responses during OGTT and IVGTT, was higher in NGT 1h-high individuals compared with NGT 1h-low individuals. NGT 1h-high individuals may represent an intermediate state of glucose intolerance between NGT and type 2 diabetes characterized by insulin resistance and reduced β-cell function, the two main pathophysiological defects responsible for the development of type 2 diabetes. Postload hyperglycemia is the result of an intrinsic β-cell defect rather than impaired incretin effect.Diabetes care 02/2012; 35(4):868-72. DOI:10.2337/dc11-2181 · 8.42 Impact Factor
Article: IGF-1 levels link estimated glomerular filtration rate to insulin resistance in obesity: A study in obese, but metabolically healthy, subjects and obese, insulin-resistant subjects[Show abstract] [Hide abstract]
ABSTRACT: Metabolically healthy but obese (MHO) subjects have a favourable cardio-metabolic risk profile, but whether they are also at lower risk for kidney dysfunction is still questionable. A total of 106 MHO, 122 normal-weight and 212 insulin-resistant obese (IRO) subjects were stratified on the basis of their insulin sensitivity and body mass index (BMI). The CKD-EPI equation was used to estimate glomerular filtration rate (eGFR) and ISI index was used to estimate insulin sensitivity. eGFR was significantly lower in IRO as compared to MHO subjects after adjusting for age, gender and BMI (P = 0.008). In a logistic regression model adjusted for age, gender and BMI, IRO subjects showed an increased risk of having eGFR in the lowest quartile (odds ratio (OR) 1.91, 95% confidence interval (CI) 1.01-3.58; P = 0.04) as compared with MHO subjects. This association was maintained when waist, lean body mass, blood pressure, HDL cholesterol, triglyceride, fasting glucose and insulin levels were additionally included into the model (OR 2.49, 95%CI 1.17-5.27; P = 0.01), but its independence was not retained with further inclusion of insulin-like growth factor-1 (IGF-1) levels (OR 2.16, 95%CI 0.93-5.04; P = 0.07) No differences in eGFR were observed between non-obese and MHO individuals. These results indicate that heterogeneity in obese phenotypes may account for conflicting evidence regarding the significance of obesity as a risk factor for chronic kidney disease. Our findings suggest that obesity is associated with lower kidney function only when insulin sensitivity is reduced, and that plasma IGF-1 is likely to be an important mechanism linking the IRO phenotype with reduced eGFR.Nutrition, metabolism, and cardiovascular diseases: NMCD 12/2011; 21(12):933-40. DOI:10.1016/j.numecd.2010.02.008 · 3.32 Impact Factor
Article: Comparison of A1C, fasting and 2-h post-load plasma glucose criteria to diagnose diabetes in Italian Caucasians[Show abstract] [Hide abstract]
ABSTRACT: The American Diabetes Association (ADA) has revised criteria for diagnosis of type 2 diabetes recommending an A1C cut point of ≥6.5% in addition to criteria based on glucose levels. We compared A1C, fasting plasma glucose (FPG) or 2-h post-challenge glucose (2-hPG) criteria for the diagnosis of diabetes in a cohort of Italian Caucasians. A total of 1019 individuals without known diabetes completed an oral glucose tolerance test (OGTT) and had A1C measured. Moderate agreement existed for A1C and FPG criteria for diagnosis of type 2 diabetes (κ coefficient = 0.522), with 85.5% of individuals classified as not having diabetes by both A1C and FPG criteria, and 5.8% classified as having diabetes by both A1C and FPG criteria. Discordant classifications occurred for 5.5% of individuals who had an A1C ≥ 6.5% and FPG <126 mg dl(-1), and for 3.2% who had an A1C <6.5% and FPG ≥126 mg dl(-1). Modest agreement existed for A1C and 2-hPG criteria for diagnosis of type 2 diabetes (κ coefficient = 0.427), with 81.8% of individuals classified as not having diabetes by both A1C and 2-hPG criteria, and 6.0% classified as having diabetes by both A1C and 2-hPG criteria. The area under the receiver operating characteristic curve of A1C for identifying subjects with diabetes according to FPG or 2-hPG criteria was 0.856 and 0.794, respectively. Modest agreement existed for A1C and FPG and/or 2-hPG criteria for diagnosis of type 2 diabetes (κ coefficient = 0.446). A1C ≥ 6.5% demonstrates a moderate agreement with fasting glucose and 2-hPG for diagnosing diabetes among adult Italian Caucasians subjects.Nutrition, metabolism, and cardiovascular diseases: NMCD 09/2011; 22(7):561-6. DOI:10.1016/j.numecd.2011.04.009 · 3.32 Impact Factor
Article: Nonalcoholic Fatty Liver Disease Is Associated with Low Circulating Levels of Insulin-Like Growth Factor-I[Show abstract] [Hide abstract]
ABSTRACT: Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease and is associated with insulin resistance and cardiovascular disease. Among the potential factors that may account for the increased cardiometabolic risk, IGF-I is a plausible candidate because the liver is the main site of its production. Our objective was to examine the relationship between NAFLD and IGF-I levels and to test the hypothesis that free fatty acids-induced insulin resistance might impair insulin-induced increase of GH receptor (GHR) expression in human hepatoma cells. SUBJECTS, DESIGN, AND SETTING: Five hundred three nondiabetic Caucasians participated in this ambulatory-care cross-sectional study. Cardiometabolic risk factors and liver ultrasound scanning were assessed. Insulin-induced expression of GHR in HuH7 human hepatoma cells exposed for 24 h to palmitate was determined by Western blotting and real-time PCR. After adjustment for age and gender, individuals with NAFLD had significantly higher body mass index, waist circumference, fasting insulin, triglycerides, homeostasis model assessment index, liver enzymes, and lower high-density lipoprotein cholesterol compared with control subjects. IGF-I levels were significantly lower in individuals with NAFLD (P = 0.001). Exposure of HuH7 hepatoma cells to palmitate caused a dose-dependent reduction in the insulin-induced increase of GHR expression. These data show that IGF-I levels are reduced in subjects with NAFLD and suggest that hepatic insulin resistance may affect IGF-I levels by modulating GH-stimulated synthesis of hepatic IGF-I.The Journal of Clinical Endocrinology and Metabolism 08/2011; 96(10):E1640-4. DOI:10.1210/jc.2011-1227 · 6.21 Impact Factor
- [Show abstract] [Hide abstract]
ABSTRACT: Glucose-tolerant subjects who have 1-h post-load glucose levels ≥155 mg dl(-1) (normal glucose tolerance (NGT)-1h-high) are at an increased risk of developing type 2 diabetes. Prospectively conducted studies indicated that high levels of liver enzymes are predictors of a tendency to develop type 2 diabetes; however, it is unknown whether the NGT-1h-high subjects are at increased risk for secreting higher levels of liver biomarkers. In this study, oral glucose tolerance tests (OGTTs) were performed in a cohort of 1000 non-diabetic Caucasians and levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and gamma-glutamyltransferase (GGT) were measured in these subjects. The NGT-1h-high subjects had increased levels of ALT and GGT, but not AST, as compared with the NGT-1h-low. Following adjustment for age and gender, the ALT, AST and GGT levels were all found to be significantly correlated with body mass index (BMI), waist circumference, blood pressure, triglycerides as well as fasting and post-challenge glucose and insulin levels. In a logistic regression analysis adjusted for age and gender, NGT-1h-high subjects were found to be at increased risk of having ALT levels in the highest quartile as compared with NGT-1h-low subjects (odds ratio (OR) = 1.71; 95% confidence interval (CI): 1.16-2.52). In addition, NGT-1 h-high subjects exhibited an increased risk for having GGT levels in the highest quartile (OR = 1.50; 95%CI: 1.02-2.17). These associations remained significant after adjustment for BMI, blood pressure and lipids, but were not significant following further adjustment for an insulin sensitivity index. NGT-1h-high subjects were at increased risk of having AST levels in the highest quartile as compared with NGT-1h-low subjects (OR = 1.51; 95%CI: 1.04-2.22). This association ceased to be significant following adjustment for BMI, blood pressure and lipids. These data suggest that a 1hPG ≥ 155 mg dl(-1) cut-off may facilitate the identification of NGT individuals at risk of developing liver abnormalities.Nutrition, metabolism, and cardiovascular diseases: NMCD 07/2011; 21(9):713-8. DOI:10.1016/j.numecd.2011.02.002 · 3.32 Impact Factor
Top Journals
- Nutrition, metabolism, and cardiovascular dis... (7)
- Diabetes care (5)
- Diabetologia (4)
- Atherosclerosis (4)
- PLoS ONE (4)
Universita' degli Studi "Magna Græcia" di Catanzaro
Catanzaro, Calabria, Italy
- Department of Medical and Surgical Sciences


text: Please Register or Log in to Remove this Advertisement! Those are actually okay. I bought a few boxes when I stumbled across them in the Jewel aisle. The Garzer has been doing quite well for himself now that we got Tice out of the building and actually brought in a good offensive line guy and some capable guards next to him.


text:
Sponsored Links
Three Credit Cards
Here is a close-up shot of three credit cards. Projects will look better with the proper pictures used as designs, so choose an appropriate one and print.
Sponsored Links
#Views: 2969 | #Prints: 187 | #Downloads: 174
Click for Printing Tips
Click for Printing Tips
Similar Printables