text:
- Filed Under
December graduates
MEQUON - Concordia University Wisconsin, Mequon, held fall commencement exercises Dec. 14. Wendy Betts of Nekoosa received a master's degree in grad ed literacy.
MENOMONIE - Local students who graduated from University of Wisconsin-Stout at the December commencement ceremony included:
? Samuel Ayres of Port Edwards, BS applied science and a business administration minor.
? Daniel Britts,of Nekoosa, BS golf enterprise management and minors in business administration and mathematics.
? Kristin Hildebrandt of Wisconsin Rapids, BS business administration.
? Jamey Karnitz of Port Edwards, BS career technical education and training.
? Jacob Marzofka of Port Edwards, BS information technology management and a business administration minor.
? Katie Napiwocki of Wisconsin Rapids, BS human development and family studies.
? Mai Lo Thao of Wisconsin Rapids, BFA art.
? Tina Vera of Nekoosa, BS management.
MADISON - Several thousand students received degrees during the University of Wisconsin-Madison's winter commencement ceremonies, Dec. 22. Wisconsin Rapids students were:
? Peter Wiley Boettcher, bachelor of science, geological engineering-geological engineering, graduated with highest distinction.
? Brandon James Hoffman, master of science, economics.
? Amanda Miller, bachelor of science, agronomy, environmental sciences, graduated with highest distinction.
EAU CLAIRE - Commencement exercises for students at the University of Wisconsin-Eau Claire were Dec. 21. Local students who received degrees and their fields of study are:
? Joyana Aiello of Nekoosa, business, BBA, marketing.
? Bradley Holck of Nekoosa, business, BBA, marketing.
? Jennifer Hess of Wisconsin Rapids, education and human sciences, BS, kinesiology.
? Brian Tessmer of Wisconsin Rapids, nursing and health sciences, BSN, nursing.
Receive honors
MENOMONIE - Carley Weisenbeck of Nekoosa is a late recipient for the spring 2013 Chancellor's Award at UW-Stout.
WAUSAU - Northcentral Technical College announces the President's List for outstanding academic achievement for the fall 2013 semester. Local students include: John Kreeger of Arpin; Robert Bauer and Arielle Kukulka of Auburndale; Daniel Blenker, Nathan Brandl and Zachary Gilmeister of Junction City; and Patrick Arts, Robert Brigando, Molli Burgeson, Jessica Hake and Amy Robinson of Wisconsin Rapids.


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RV Rental in Atlanta (South), GA
The International Hartsfield – Jackson Airport in Atlanta is the world's leader in moving passengers. Obviously, this is a hot city (not just temperature hot), steeped in deep Southern roots. There is no better way to explore this town than in the comfort of one of our Atlanta South RV Rentals. Our rental location is conveniently located in Palmetto, Georgia, just a half-hour south of Atlanta. Palmetto is a small, quiet town, unlike its giant neighbor, Atlanta … just 29 miles to the north.
While visiting Atlanta, you will find weeks worth of things to do, so it would take more than one visit to experience it all. You could explore the Atlanta Aquarium, where you will find 100,000 marine animals residing in six themed underwater galleries. Continuing with the animal theme, you can see the most extensive collection of orangutans and gorillas in the nation at the Zoo Atlanta. Take the kids to the LEGOLAND Discovery Center, or take a tour of the CNN Studios. You can dine at the Hard Rock Café if you choose not to cook in the comfort of your motorhome. And speaking of motorhomes, there are plenty of great RV parks in the area.
If you choose to make a departure from the city and get away on some interesting daytrips, there are plenty to choose from. Here are some ideas:
A two-hour trip from Atlanta could land you in Stone Mountain Park. This is Georgia's most visited attraction. Close to 4,000,000 fun seekers visit this fun park each year to enjoy the 3,200 acres of camping, golfing and hiking and attractions. The park is a mix of fun and entertainment for the whole family, including the world's largest laser show. There's even a petting zoo and a play area for the kids, complete with concession stands. There are live shows and shops in the village, and you can ride a tram right to the top of the mountain … or take a riverboat cruise. There's truly something for everyone. There is an admission cost, but it's well worth the entertainment value. From Atlanta, take I-85 North to I-285 East. Once on I-285 East, take Exit 39B, the U.S. Hwy 78 East (Snellville/Athens) exit. Travel 7.7 miles and take exit 8, the Stone Mountain Park Main Entrance. Follow the exit ramp to the East Gate entrance of Stone Mountain Park.
In less than 3.5 hours from Atlanta, you can pilot your Cruise America rental RV to North Carolina's famed Black Rock Mountain State Park. It's the highest state park in Georgia, located in the Blue Ridge Mountains. It's found in the northeast corner of the state, close to Mountain City. There are breathtaking views from several outlooks in the park. If the day is clear, you can enjoy great views of North and South Carolina, as well as the highest peaks of the Great Smoky Mountains in Tennessee. That's a lot to take in! While in the park, you can fish or paddleboat on the beautiful 17-acre lake. There is plenty of nearby RV camping available, so you can plan on staying the night if you please. To get there from Atlanta, just take I-85 N through the Carolinas. It's a 221-mile trip, so you will enjoy a lot of sight seeing along the way.
Regardless of your destination in Georgia, or any of the nearby states, it can't get any better than experiencing it in one of Cruise America's class C RVs.
RV Rentals in Atlanta (South), GA
7940 Bowen Rd.
Palmetto, Georgia, 30268
(800) 549-2304
Check Rates

subset: commoncrawl


text: http://www.icpsr.umich.edu/ 2008-11-05T08:11:39-05:00 Updates to Capital Punishment in the United States, 1973-2001 (ICPSR 3947) ICPSR firstname.lastname@example.com ICPSR http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/3947-2008-11-05T01:00:00-05:00 2008-11-05T01:00:00-05:00 2008-11-05T01:00:00-05:00 ICPSR 3947 was updated on 2008-11-05, please download updated files 2008-11-05 Minor changes have been made to the metadata. http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/3947-2008-10-30T01:00:00-05:00 2008-10-30T01:00:00-05:00 2008-10-30T01:00:00-05:00 ICPSR 3947 was updated on 2008-10-30, please download updated files 2008-10-30 All parts have been moved to restricted access and are available only using the restricted access procedures. http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/3947-2005-11-04T01:00:00-05:00 2005-11-04T01:00:00-05:00 2005-11-04T01:00:00-05:00 ICPSR 3947 was updated on 2005-11-04, please download updated files 2005-11-04 On 2005-03-14 new files were added to one or more datasets. These files included additional setup files as well as one or more of the following: SAS program, SAS transport, SPSS portable, and Stata system files. The metadata record was revised 2005-11-04 to reflect these additions. http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/3947-2004-03-30T12:00:00-05:00 2004-03-30T12:00:00-05:00 2004-03-30T12:00:00-05:00 ICPSR 3947 was originally relased on 2004-03-30. Original ICPSR release.


text: 8C here this am under partly cloudy skies; forecast is for light showers, beginning late this pm and lasting through the weekend. Looks like the nod will go to the F5 or F6 (well-sealed against moisture). Not great weather for the E100G (what I wouldn't give for some Provia 400), so HP5+ will get the nod (a 200 EI or 1000 EI rating, depending on the cloud cover).


text:
Low metal reverberation and tape manipulation recorded on 1/4" tape, cut-up and physically looped
Metal reverberation with intermittent popping and tape manipulation recorded on 1/4" tape, cut up and physically looped
speedcore kick drum loops synthesized in buzz tracker
Pitched down thrumming, droning washing machine recorded on 1/4" tape and physically looped (loop it)
mixed basses together
Layered droning metal reverberation recorded on 1/4" tape and physically looped
Metal reverberation warbling and tape-manipulation induced wowing, recorded on 1/4" tape and physically looped
Remix of http://www.freesound.org/people/jonnay/sounds/2518/ Stretched and processed different ways in Sonar 7. Modulation and dynamic processing added in Cood Edit.
Created using spectral freezing max patch. Some may have pops and clicks or audible looping but shouldn't be hard to ...
just me messing with some things in fruity loops. been a while.
Sci-Fi dronescape. Fades out. Doesn't loop very nicely because of that fade.
drum n bass, bassline
A modification of a file I created as another user. I crumpled a 2 liter plastic soda bottle and distorted ...
Pulsating Bass synth ran through tape. A bit like the one in Tron Legacy by Daft Punk


text:
May 22, 2015
Sandeep Dutta has been named president of the India-based film supplier's US operation.
May 18, 2015
James Murphy has played a key role with Davis-Standard for more than 25 years, progressing through various positions.
May 14, 2015
Before joining Discount Labels, Brian Webb was a business development manager at Standard Register.
May 13, 2015
TLMI President Frank Sablone will be stepping down from his daily activities effective January 1, 2016.
May 12, 2015
Tapp will focus on overseeing all of IPB's business and operations, with an emphasis on growing the company.
May 8, 2015
ACS partners with customers for technical advice ranging from new product selection to application-specific consultation.
Greg Hrinya, Associate Editor||May 6, 2015
The Webtron 450 flexo press operated at top speeds of 300 fpm.
May 6, 2015
A look at KDV's reconditioned Webtron Press and the company's Waukesha, WI, USA facility.
Greg Hrinya, Associate Editor||May 5, 2015
Forecasts, spending habits, brand protection solutions and interactive packaging trends were among the topics discussed.
May 5, 2015
Paul Lancelle, Jennye Scott and Richard Black all received honors.
May 1, 2015
Mitch Butier, president and chief operating officer, previously handled the duties on an interim basis.
April 29, 2015
Jouko Lahepelto is the former senior vice president of sales, Americas, for UPM Raflatac.
April 24, 2015
EFI has also announced that Marc Olin will take over as the chief financial officer.
April 22, 2015
The moves coincide with the press manufacturer's continued growth in the European market.
April 22, 2015
Michael Beedles assumes the position previously held by Bob Linse.
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text:
or me If you know SD City and the situation it's in you can see why the roads are a mess. Coming him from the airshow I got caught in the rain. Somewhere in there I got a snakebite off of one of those quarter sized rocks due to the zero street sweeping going on. Well, as I start across a painted zone BAM, I go down like a left hook from Ali. Major road rash but the bike faired ok. If it wasn't for the slow leak I would have been ok.
I could rant for hours about the condition of our roads but the best I can do is to hit the website and report bad road spots and hope they get fixed before the year changes. Do they make solid rubber road tires?


text:
The San Juan Medical Foundation
Formally established in 1985, the San Juan Medical Foundation (SJMF) is a community-based organization committed to the future of healthy people throughout the Four Corners Region of New Mexico, Arizona, Colorado, and Utah.
The Foundation is an independent non-profit, non-governmental organization which was formed to receive and administer funds for charitable, scientific, and educational purposes to improve health in our region.
Save The Date:
Breast Cancer Luncheon &
Style Show
Wednesday, October 28th
Pinon Hills Community Church
Tickets on sale Oct. 1
Get Pinked Cowboy Soiree
Saturday, October 24th
Farmington Civic Center
The SJMF Mission
The San Juan Medical Foundation is a community-based, independent, non-profit organization committed to enhancing health care in the Four Corners region in cooperation with San Juan Regional Medical Center.


text:
Yesterday I peeped into Elizabeth Taylor's closet, drooling over the fist-size diamonds and technicolor caftans on display at Christie's auction house.
But while I won't be bidding on any of those security-guard-mandating pieces at their upcoming sale, I might just be able to buy a little something of Ms. Taylor's after all.
From now through December 17, Christie's is auctioning 950 of Elizabeth's personal items in their first ever online only sale. Starting at just $100, the lots are lower priced than the main auction, but equally as fabulous: Art Deco brooches, Dior clutches and Valentino blouses all worn and loved by the late screen siren.
When I last visited the site, I found a Chanel blouse going for $150 and a 1920s bracelet hovering at $400. Finally I know exactly where to find ultra-glam, vintage holiday gifts with some serious history behind them.
More on Luckymag.com:
- Win A Car!
- Lisa Frank Is Making Clothes for Adults
- Cute Workout Wear to Sweat Over (And In)
- Video: How Many Lucky Editors Can We Fit in a Hyundai?
- Get More Lucky
Keep up with the Lucky team on Twitter: Follow @LuckyMagazine


text:
|Rosaceae (ro-ZAY-see-ee) (Info)
|Malus (MAY-lus) (Info)
|by Father John L. Fiala
|Registered or introduced:
6-8 ft. (1.8-2.4 m)
8-10 ft. (2.4-3 m)
6-8 ft. (1.8-2.4 m)
8-10 ft. (2.4-3 m)
USDA Zone 4a: to -34.4 �C (-30 �F)
USDA Zone 4b: to -31.6 �C (-25 �F)
USDA Zone 5a: to -28.8 �C (-20 �F)
USDA Zone 5b: to -26.1 �C (-15 �F)
USDA Zone 6a: to -23.3 �C (-10 �F)
USDA Zone 6b: to -20.5 �C (-5 �F)
USDA Zone 7a: to -17.7 �C (0 �F)
USDA Zone 7b: to -14.9 �C (5 �F)
USDA Zone 8a: to -12.2 �C (10 �F)
USDA Zone 8b: to -9.4 �C (15 �F)
Full Sun
Sun to Partial Shade
Mid season flowering
Resistant to Apple Scab
Resistant to Apple Powdery Mildew
Resistant to Cedar-Apple Rust
Resistant to Fireblight
From softwood cuttings
By grafting
By budding
This plant is attractive to bees, butterflies and/or birds
Flowers are fragrant
Average Water Needs; Water regularly; do not overwater
This plant has been said to grow in the following regions:
Clermont, Kentucky
Georgetown, Kentucky
Lexington, Kentucky
Louisville, Kentucky
On Mar 3, 2007, ViburnumValley from Scott County, KY (Zone 5b) wrote:
'Leprechaun' crabapple is a fine little tree for constrained landscapes, growing only to 8 ft high (2.4 m). It has leathery, dark green disease free leaves. The flower buds emerge red, opening to an abundance of single white blossoms that bloom especially on spurs. The fall fruit is small and bright red, and remains firm and colorful into December.


text:
Pokemon Darkend Skys version
View Single Post
October 2nd, 2008 (4:17 PM). Edited October 2nd, 2008 by Kyuubi12.
Join Date: Aug 2008
Posts: 17
Hello People, I am Kyuubi12 this is My first Official Thread.
This is a game in Process.
So far 0% started
My Idea for this story is:
You are Inside with your Mom & Sis.After that Everything turns Dark, For a Few min, The power is out and prof Debbie (Aunt) is at your House.She asks you if you would Help Her with a Project.She gives you 10 pokeballs. Later Officer Jenny comes by while you and Prof. Debbie are going to the Lab to get A Get a Pokemon generator.Officer Jenny says that A wild and very angry Darkcas ( Dark Water ) is at your house. once you encounter Darkas, Prof Debbie Lends you Darmas( Dark/fire ) your Job is to catch Dacas not Ko It, After that you start your adventure as a Pokemon Trainer.More to Come Later.
Working on awsome Maps,Sprites,Scripts,Iteams,Pokemon.
The Area where your at is
The Sunny Ray Islands. It South of Sinnoh
You Live on Shell Island 14-20 Miles from Sunny Ray Island.
I need The Following.
5 Tilest
1 Title Screen Maker
Everyone Supporters
8 Mappers
4 People with a good imagaination and Brain.
Thank you for Reading
Games im with.
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text:
Fayetteville veterinarian and owner of Lyndon Veterinary Clinic, Dr. Eric Davis, recently donated animal rescue kits to three local fire departments after learning how inappropriate human masks fit dogs and cats.
"Most of us view our animal companions as family members and would hope and expect that family pets could also be resuscitated by rescue crews if they were overcome by smoke or carbon monoxide," Davis said. "However, most people do not appreciate the fact that face masks designed to provide oxygen to humans do not work effectively to resuscitate animals."
Davis and his wife, Hannah, therefore, donated a total of eight O2 Fur Life rescue kits to be carried on trucks of the Syracuse, Jamesville and Fayetteville fire departments. The DeWitt Fire District was already equipped, he said.
Each kit contains three masks: small, medium and large, with tubing that can be attached to an oxygen supply carried on the emergency vehicle. It also includes a leash that can be converted into a collar, and a pliable bag to gently tuck in and restrain the body of a flailing cat so no one gets injured after the feline has been resuscitated. The masks are useful in treating animals overcome by smoke inhalation, carbon monoxide or near-drowning.
"Think about the nose of an average-sized person compared to the nose of a beagle, Labrador retriever or even a kitty," Davis said.
The configuration of a dog or cat's face is not at all similar to humans. To help demonstrate the inadequacy of human oxygen masks for animals, Davis brought his dog, a smooth-coat Collie named Apache, and his cat, Itty Bitty Kitty, to training sessions he scheduled with fire members and emergency medical technicians at each fire station.
"Apache has an amazingly long and impressive snoot, a nose that would be truly 'out of joint' if the proper equipment were not available in an emergency," he said.
Rescue cat Itty Bitty Kitty was born with a congenital neurological abnormality of her rear legs.
"It's the kind of thing that nobody really thinks about until there's an emergency," Davis said. "I didn't know there was a need for it myself."
The rescue kits sell for approximately $70 each retail cost.
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text:
The Untold Story of the Bay of Pigs
Dallek, Robert, Newsweek
Byline: Robert Dallek
Newly declassified CIA documents reveal new blunders and how close America came to war during the failed invasion of Cuba.
From a transport ship floating in Cuba's Bay of Pigs, CIA operative Grayston Lynch knew the U.S. mission to overthrow Fidel Castro was faltering. The Cuban exiles he had brought with him had abandoned their posts, so he grabbed the boat's recoilless rifles and machine guns and began firing at the aircraft overhead.
On a day of chaos and infamy in April 1961, Lynch would soon understand the consequences of his shooting. He had fired on his agency's own planes, which were trying to protect the U.S.-led Cuban exiles invading the island from being slaughtered by Castro's forces. "We couldn't tell them from the Castro planes," Lynch later explained.
The Bay of Pigs is one of America's most infamous Cold War blunders, and it has been studied, debated, and dramatized endlessly ever since. Yet, for 50 years, details like Lynch's story were hidden away in top-secret CIA files that were finally released this month and reviewed by NEWSWEEK.
The CIA's official history of the Bay of Pigs operation is filled with dramatic and harrowing details that not only lay bare the strategic, logistical, and political problems that doomed the invasion, but also how the still-green President John F. Kennedy scrambled to keep the U.S. from entering into a full conflict with Cuba.
The disclosure is the handiwork of the dogged researcher Peter Kornbluh and his Washington-based National Security Archive. The right-to-know group used the Freedom of Information Act and lawsuits to force the CIA to release all its major documents on Kennedy's failed efforts to overthrow Castro, who this month turned 85 and stands as a living reminder of America's failure to repel communism on an island just 90 miles from Florida.
Written by then-CIA chief historian Jack Pfeiffer between 1974 and 1984, the five-volume history--the last volume of which remains classified--seeks to spread the blame beyond the agency to the State Department and White House, while confirming that the invasion was even more disastrously handled than previously known.
Among the details hidden from public view all these years are that a CIA official transferred funds from the invasion budget to "pay the mafia types" for an assassination plot against Castro, which was so secret that the chief of invasion planning, Jacob Esterline, was not told what the money was for. Despite repeated White House instructions to keep U.S. forces from directly participating in order to preserve plausible deniability of American involvement, the CIA ultimately gave permission for U.S. pilots to fly aircraft over the beaches. The aviators were told that, if they were shot down and captured, they should describe themselves as mercenaries and the U.S. would "deny any knowledge" of them. Sadly, four U.S. airmen lost their lives, and it wasn't until 1976 that they were given medals in ceremonies their families were encouraged to keep secret. Before Kennedy inherited the Bay of Pigs invasion plan from the Eisenhower administration, then-vice president Richard Nixon was a forceful advocate of bringing down Castro and urged the CIA to support "goon squads and other direct action groups" operating inside and outside Cuba.
Perhaps most disturbing of all, the CIA task force in charge of the paramilitary assault did not believe it could succeed without becoming an open invasion supported by the U.S. military. The assessment was part of a brief prepared for President-elect Kennedy that he never saw. …


text: AdChoices Cookie Consent Terms of Use Privacy Policy Hide GALLERIES Ron Livingston Ron Livingston Photos 5/15 Ron Livingston AskMen Editors April 3, 2007 Share Tweet 0 Shares Livingston has done about as much work on the big and small screens, but he's better known for his television work than for his film appearances. His movie resume includes parts in Swingers (1996), Office Space (1999), Adaptation (2002), and Little Black Book (2004), while his TV credits include Band of Brothers (2001), Sex and the City (2002-03), and Standoff (2006-07). Continue reading Ron Livingston's profile. Next Slide gallery Comments Show Comments More Like This Celeb Galleries Brittany Murphy Read More Around the Web Special Features Special Feature Proof You Can Eat What You Want And Still Get Ripped Read More Special Feature The 25 Sexiest Moments Hollywood Dared To Put On TV Read More


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Leather-look trousers by RUT & CIRCLE. Two slant pockets with zippers to front. Zip and button fly fastening and belt loops around waist. Sections in contrast material along legs and at the back of knee. Made of 60% Polyurethane and 40% Viscose. Contrast material of 65% Viscose, 30% Polyester and 5% Elastane.
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Rut&Circle offer on trend clothes and fashion that includes dresses, pants, shirts, and accessories, at competitive prices. Rut&Circle are passionate about fashion and design. When developing a collection, Rut&Circle always apply the motto "Fashion you can afford to love." Discover a Rut&Circle piece to love here at Nelly.com UK.
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Free delivery when you spend over £75. Standard shipping £3.95.
Delivery time: 3-6 days.
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go to for more info. (8) Brand new 4 plexes side by side on the west side of Missoula. Close to interstate access, airport, and one of Missoula's largest private employers. Each building has (4) 2 bedroom 1 bath units with washer & dryer hook ups that are 850 sqft. Fully landscaped with underground sprinklers. Hardy Plank siding. Each unit is separately metered fro utilities. Very nice upper end 4 plex's in a highly desirable residential neighborhood.
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Crisis Prevention & Recovery
Iraq faces a large-scale humanitarian crisis. Alarming development gaps and security risks directly affect 5 million people, of which nearly 2.5 million have fled their homes in the central and northern regions, seeking refuge in Kurdistan, and other governorates such as Karbala, Diyala, Najaf and Basra. The Kurdistan Region of Iraq itself hosts 970,000 displaced persons and 245,000 Syrian refugees (as of March 2015). The impact of this unprecedented humanitarian crisis extends beyond populations to all institutions, systems and political processes.More
Our Goals
UNDP helps achieve an early recovery and rapid return to sustainable development pathways in post-conflict and post-disaster settingsmore
Our Stories
In Basra, displaced people do not give up on dreams of a better life
Survival can be summed up in three words – never give up. This is the saying of thousands of internally displaced people (IDP), who fled violencemore
- View More Stories
Cash-for-work, a boost for vulnerable displaced families
While most jobs involve manual labour and thus employ men, their entire families benefit from the short-term income they bring in. Cash-for-work provided temporary income to 2,360 displaced persons in camps in 2014.more
Projects and Initiatives
Iraq Crisis Response and Resilience Programme
Iraq faces a large-scale humanitarian crisis. Alarming development gaps and security risks affect 5 million people, of which nearly 2.5 million have fled their homes in the central and northern regions, in addition to 245,000 Syrians seeking refuge in Kurdistan. UNDP leads the UN support to employment and income generation through local NGO partners, so that people are able to take care of themselves and become less dependent on handouts. more
Umm Qasr Sustainable Navigational Aids
Over 25 years the level of maritime traffic in Iraq has significantly declined, and a lack of visual navigation aids have restricted the full recovery of the industry. This project enhances visual navigation aids at Iraq's southern port to meet international standards. more
Drought Risk Management
Given the frequency of drought in Iraq, its area of effect, and impact on people's lives, it is considered a natural disaster requiring immediate attention and mitigation. This project helps develop a national plan to help Iraq manage the risk of drought. more


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Increase privacy without sacrificing style. Simply turn to Isabelle's Window Design, based in Vestal, New... more
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CasuallyElegantHome brings elegance and beauty to your home. Make your Home Casually Elegant. Get various... more
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text:
Main News Page
Thursday, May 29, 2014
More items for
Coating Materials
Rust-Oleum Corp. says its new fungicidal primer can kill mildew, mold and odor-causing bacteria on industrial and other applications.
Zinsser Mold Killing Primer is a water-based coating that can be used on both non-porous interior and exterior surfaces.
It can be applied directly over problem areas without extensive surface preparation and contains an Environmental Protection Agency-registered antimicrobial agent to prevent the growth of mold and mildew on paint film, according to the Vernon Hills, IL-based specialty paints and coatings manufacturer.
The protective primer can be applied directly over mold and mildew on interior and exterior surfaces.
Recommended applications include factories, office buildings, basements, window frames and bathrooms.
Additional Features
"Mold and mildew are serious problems when they occur, often causing unsightly stains and a lingering odor," said Fiona Seal, a brand manager for Rust-Oleum. "Unfortunately, they are also one of the most difficult fungi to remove."
Zinsser Mold Killing Primer will dry to a bright white in as little as 30 minutes, and can be topcoated after one hour, according to Rust-Oleum.
The company says that full adhesion and hardness will develop within seven days of application.
The product is available in quarts, gallons and five-gallon containers. One gallon will cover 400-450 square feet.
More information: rustoleum.com.
Comment from Tom Schwerdt, (5/29/2014, 12:54 PM)
Impressive. I don't recall any other major manufacturer offering a latex to paint directly over active mold, unless you go back to the days of mercury additives...
Join the Conversation:
Performance Amine 1,3-BAC
A highly reactive cycloaliphatic diamine offering superior performance. Reasonable cost and curing efficacy makes it suitable for all types of epoxy resin applications.
Sherwin-Williams Protective & Marine Coatings
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Polyflex™ new Polyurea Geotextile Membrane System has been specifically engineered to protect the environment in containment applications.www.polyflexlinings.com
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text:
If you are 42 and want to conceiving a baby, then I suggest you put in the time and efforts to learn what can increase your chance of conceiving and giving birth to a kid at that age, since as you may already know, your chance of naturally conceiving at 42 are greatly been reduced than what they were say 10 years ago. Nonetheless, using some special and specific recommendations, you can enhance them and have the joy of naturally conceiving a baby.
Yes, a woman can get Pregnant at Age 42 with no Fertility Treatments. I think as long as you're ovulating, you can naturally conceive and give birth to a kid. However, why not increase your chances naturally? Natural methods for increasing your probability of getting pregnant at 42 are safe and usually are void of any side effects - so it could be a good thing to try them out.
If you wish to learn some effective natural techniques that can increase a woman's chances to to get pregnant at age 42, then I suggest you get a copy of the pregnancy miracle guide: http://www.articlesbase.com/
Just follow this link ==> http://pregnancy-
Related: http://www.articlesbase.com/


text:
basically awesome in everyway, prove me wrong.
Join OkCupid
Find better matches with our advanced
Find better matches with our advanced
matching system
—% Match
—% Enemy
34 • Sacramento, CA • Man
I'm looking for
- Women
- Ages 18-40
- Near me
- Who are single
- For new friends, long-term dating, short-term dating, casual sex
My details
- Last online
- Aug 12, 2013
- Orientation
- Straight
- Status
- Single
- Speaks
- English
My self-summary
Write a little about yourself. Just a paragraph will do.
What I'm doing with my life
Don't overthink this one; tell us what you're doing day-to-day.
health insurance keeps me playing hard
I'm really good at
Go on, brag a little (or a lot). We won't judge.
making people smile, its true.
The first things people usually notice about me
I'm an empty essay… fill me out!
my really big... persona
Favorite books, movies, shows, music, and food
Help your potential matches find common interests.
if you got dozens of stars in elementary for the book board, i was the kid with one and a half, doesn't mean i havn't grown into a complete gem...
The six things I could never do without
Think outside the box. Sometimes the little things can say a lot.
survival of the fittest"" actually means fit for environment, when combined with our ability for reason, the apes never stood a chance...
I spend a lot of time thinking about
Global warming, lunch, or your next vacation… it's all fair game.
why people spend so much time worrying
On a typical Friday night I am
Netflix and takeout, or getting your party on — how do you let loose?
getting the dance floor moving.
The most private thing I'm willing to admit
I'm an empty essay… fill me out!
my only secrets are other peoples
You should message me if
Offer a few tips to help matches win you over.
you understand my last name isn't class"
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text:
Khamyab District
From Wikipedia, the free encyclopedia
Khamyab District is a frontier district in the province of Jozjan in Afghanistan. It shares borders with Turkmenistan to the north and west, Khwaja du koh District to the south and the Mingajik and Qarqin districts to the east. As of 2006, the population is 12,400. The district center is the village of Khamyab (Kham-e Ab). The river Amu Darya flows in the northern end of the district and forms part of the border with Turkmenistan.
District Map[edit]
|This Jowzjan Province, Afghanistan location article is a stub. You can help Wikipedia by expanding it.


text:
As the dust settles from the Round 1 MBA application rounds, there's good news for some and there's additional work to be done for the others. A few questions that applicants ask: Is it worthwhile applying to Round 2? Or am I doomed coz I didn't make it through in Round 1? What should my MBA application strategy be?
Everyone talks about how important it is to apply in Round 1. We know the arguments and the justifications there. But if you haven't struck gold yet, don't worry. The fact that schools have a Round 2 AND a Round 3 means they are still looking for good candidates to include in their incoming class. So for whatever reasons (just got the GMAT score, maybe essays weren't impactful enough, maybe the MBA interview preparation could've been stronger, maybe you forgot to wear your Shani Suraksha Kavach) if your success with business school applications has been delayed, it's time to take a breather and re-evaluate your Round 2 strategy.
If your Round 1 approach hasn't worked as you thought, try to evaluate why. No point in just rushing in 6 more applications that look and sound exactly the same. Was it your choice of schools? Was it your story-line? Was it your post-MBA goal?
Quite a few people have approached us for the MBA MAP as they wanted to discard any baggage from Round 1 and start afresh – starting from the choice of schools and the overall approach.
If you are convinced and confident about your R1 application strategy, then you could still go ahead with the same approach. Maybe it was just the intense competition.
If you have any theories of what might have gone wrong in R1 and what you plan to do differently in R2, share your stories as (anonymous) comments. We'd be glad to share our thoughts.


text:
Once you are voted in you learn the secrets of the hook ;), our secret handshake and be able to travel the world and be welcomed as a tower crane operator at building sites everywhere. The money and power is great but just remember with this power comes great responsibility,
Every week I am on a worksite more often than not I will be asked "how do you become a tower crane operator" enquiring on how to enter our closed secret society. At great risk I am going to reveal this secret and I hope my brother tower crane operators will not be to upset. Well... basically you have to be born into it with your father being a crane operator and his father before him, either that or have three tower crane operators vouch for you before entering you districts tower crane lodge, then you go to a meeting arguing your case why you should be a tower crane operator. Lodges differ from district to district with some requiring a majority vote from its members, others a unanimous vote.
Once you are voted in you learn the secrets of the hook ;), our secret handshake and be able to travel the world and be welcomed as a tower crane operator at building sites everywhere. The money and power is great but just remember with this power comes great responsibility,
Crane Collapse due to heat
Building is underway to build more campuses for the ever expanding University of Technology, Sydney. Once seen as a second tier uni compared to UNSW, Sydney University and Macquarie University, it seems it is flush with funds and expanding at incredible pace. It is currently in the progress of building a Frank Gehry designed building near the Ultimo TAFE building, and this site at Broadway which for people who do not know Sydney is just outside of where the city starts.
The crane failed from a fire that weakened the steel causing it to collapse from its own weight, however the interesting thing is that whilst the jib is a total wreck as well as the platform and perhaps the controls, the tower crane mast seems to be intact.
The crane was removed however the mast remained, it was quite interesting an empty mast on a running building site, however it was also disrupting, on the weekend the site would get permits to block off the street and have a couple of large mobile cranes lifting and unfortunately this is the way i go to much work.
We that has come to an end, there is now a new crane in on that mast, I will upgrade with pictures asap, they work very long hours on that site, I imagine they must have a lot of work to catch up on, with all that overtime the crane operator will have no mortgage at the end of this job I imagine, good luck to him :)
The load chart
tower crane load chart
An important part of the tower crane is the load chart, really it is essential that the crane operator as well as the crane crew knows the load chart back to front. The chart will tell the crane operator as well as his dogman,and rigger what they can lift at what radius for the configuration the crane is set up in.
Our crane is set up at 50 meters and at the moment it is in 2 part meaning that 2 cables go to the hook block, this crane allows for 2 part and four part (the different configurations allow for different mechenical advantage and alter the lifting capacity of the crane)
From the load chart we know we can lift 1300kgs at 50 meters (the furtherest point) Care must be taken to allow for the weight of the lifting chains and the crane cable weight.
Whilst there are indicators on the control pannel on the crane that tell you how much lifting capacity you have it is important to know the chart as you do not want to pick up a load within capacity and not be able to land it in the required spot due to it being out of lifting capacity.
November 2015
My name is Matthew and I am the owner of a company that provides personnel for tower cranes on building sites in Sydney, Australia.


text:
Page 1
Brief Communication
Presynaptic Ca2?Entry Is Unchanged during Hippocampal Mossy
Fiber Long-Term Potentiation
Haruyuki Kamiya,1,2Kazumasa Umeda,1,3Seiji Ozawa,2,4and Toshiya Manabe1,5
1Division of Cell Biology and Neurophysiology, Department of Neuroscience, Faculty of Medicine, Kobe University, Kobe,
Hyogo 650-0017, Japan,2Department of Physiology, Gunma University School of Medicine, Maebashi, Gunma
371-8511, Japan,3Department of Applied Biology, Kyoto Institute of Technology, Kyoto 606-8585, Japan,4Core
Research for Evolutional Science and Technology, Japan Science and Technology Corporation, Kawaguchi, Saitama
332-0012, Japan, and5Division of Neuronal Network, Department of Basic Medical Sciences, Institute of Medical
Science, University of Tokyo, Tokyo 108-8639, Japan
The hippocampal mossy fiber (MF)–CA3 synapse exhibits
NMDA receptor-independent long-term potentiation (LTP),
which is expressed by presynaptic mechanisms leading to
persistent enhancement of transmitter release. Recent studies
have identified several molecules that may play an important
role in MF-LTP. These include Rab3A, RIM1?, kainate autore-
ceptor, and hyperpolarization-activated cation channel (Ih).
However, the precise cellular expression mechanism remains to
be determined because some studies noticed essential roles of
release machinery molecules, whereas others suggested mod-
ulation of the ionotropic processes affecting Ca2?entry into the
presynaptic terminals. Using fluorescence recordings of pre-
synaptic Ca2?in hippocampal slices, here we demonstrated
that MF-LTP is not accompanied by an increase in presynaptic
Ca2?influx during an action potential. Whole-cell recordings
from CA3 neurons revealed long-lasting increases in mean
frequency, but not mean amplitude, of miniature EPSCs after
the high-frequency stimulation of MFs. These data indicate that
the presynaptic expression mechanisms responsible for en-
hanced transmitter release during MF-LTP involve persistent
modification of presynaptic molecular targets residing down-
stream of Ca2?entry.
Key words: cAMP; hippocampus; long-term potentiation;
mossy fiber; presynaptic Ca2?influx; transmitter release
The hippocampal mossy fiber (MF) synapse provides major ex-
citatory input onto CA3 pyramidal neurons and exhibits robust
short- and long-term presynaptic plasticity (Zalutsky and Nicoll,
1990; Weisskopf and Nicoll, 1995; Kobayashi et al., 1996; Henze
et al., 2000) independent of activation of NMDA receptors
(Nicoll and Malenka, 1995). Because long-term potentiation
(LTP) at this synapse can be induced without postsynaptic acti-
vation (Castillo et al., 1994; Mellor and Nicoll, 2001) (but see
Yeckel et al., 1999) and is blocked by the inhibitors of protein
kinase A (PKA), it has been proposed that a rise in cAMP
concentration within the presynaptic terminals and subsequent
activation of PKA are essential for induction of MF-LTP (Weiss-
kopf and Nicoll, 1994). Recently, several studies have revealed the
molecular targets of the cAMP signaling pathway. The studies of
mice lacking Rab3A (Castillo et al., 1997) and RIM1? (Castillo
et al., 2002) suggested essential roles of these two proteins in
MF-LTP. Because RIM1? is an active zone protein that interacts
with the synaptic vesicle protein Rab3A, changes in vesicular
mobilization rather than modification of ion entry processes
would be expected. However, this notion was challenged by the
recent report by Mellor et al. (2002) showing that blockers of the
hyperpolarization-activated cation channel (Ih), whose activity is
modulated directly by cAMP, reversed already established MF-
LTP. The authors proposed a hypothesis that cAMP-dependent
modification of Ihresults in long-lasting depolarization of MF
terminals. Depolarization of the terminals would enhance trans-
mitter release by either increasing Ca2?entry via broadening of
action potentials (Geiger and Jonas, 2000) or activating Ca2?
channels to elevate intraterminal basal Ca2?levels (Turecek and
Trussell, 2001). It must be noted that Chevaleyre and Castillo
(2002) put through the new paper reporting strong evidence
against involvement of Ihin the expression of MF-LTP (see
Discussion). Other lines of evidence suggesting involvement of
presynaptic kainate receptors in MF-LTP (Contractor et al.,
2001; Lauri et al., 2001) (but see Nicoll et al., 2000) also imply
modulation of the presynaptic Ca2?dynamics, because kainate
autoreceptors at this particular synapse was demonstrated to
operate by an ionotropic mechanism (Kamiya and Ozawa, 2000;
Schmitz et al., 2001).
Two possibilities suggested by these studies (i.e., modification
of downstream steps involving vesicular mobilization as suggested
by the studies of Rab3A and RIM1? knockout mice, or modula-
tion of presynaptic Ca2?dynamics as suggested by involvement
of Ihor kainate autoreceptors) are apparently contradictory, and
it has been difficult to propose the unifying model at this time. To
directly determine whether Ca2?entry is modified, we adopted
fluorescence measurement of presynaptic Ca2?at MF terminals
(Kamiya and Ozawa, 1999) and found that action potential-
driven presynaptic Ca2?influx is unchanged during the expres-
Received Aug. 16, 2002; revised Sept. 17, 2002; accepted Oct. 7, 2002.
This work was supported by Grants-in-Aid for Science Research (H.K., S.O., and
T.M.), by Special Coordination Funds for Promoting Science and Technology
(T.M.) from the Ministry of Education, Science, Sports, Culture and Technology of
Japan, and by grants from the Ichiro Kanehara Foundation and the Novartis
Foundation (Japan) for the Promotion of Science (T.M.). We thank Prof. Atsu Aiba
for reading this manuscript.
Correspondence should be addressed to Haruyuki Kamiya, Division of Cell
Biology and Neurophysiology, Department of Neuroscience, Faculty of Medicine,
Kobe University, Kobe, Hyogo 650-0017, Japan. E-mail: email@example.com.
Copyright © 2002 Society for Neuroscience 0270-6474/02/2210524-05$15.00/0
The Journal of Neuroscience, December 15, 2002, 22(24):10524–10528
Page 2
sion of MF-LTP. Our results strongly support the hypothesis that
the presynaptic expression mechanism responsible for MF-LTP is
persistent modification of the release machinery downstream of
Simultaneous recordings of field EPSPs and presynaptic Ca2?. Transverse
hippocampal slices (?400 ?m thick) were prepared from BALB/c mice
(14–20 d of age). All experiments were performed according to the
guidelines established by the Animal Care and Experimentation Com-
mittees of Gunma University and Kobe University. Slices were contin-
uously superfused with a solution composed of the following (in mM):
127 NaCl, 1.5 KCl, 1.2 KH2PO4, 2.4 CaCl2, 1.3 MgSO4, 26 NaHCO3, and
10 glucose. The solution was equilibrated with 95% O2and 5% CO2.
Electrical stimuli (100 ?sec duration, ?500 ?A intensity) were delivered
through a tungsten concentric bipolar electrode inserted into the stratum
granulosum of the dentate gyrus, and the resultant field EPSPs were
recorded from the stratum lucidum in the CA3 region with glass micro-
electrodes of ?10 ?m tip diameter filled with the standard extracellular
solution (Kamiya et al., 1996). All recordings were made at room tem-
perature (24–28°C).
Fluorescence recordings of presynaptic Ca2?within the mossy fiber
terminals were made as described previously (Kamiya and Ozawa, 1999).
Briefly, rhod-2 AM (Dojindo Laboratory, Kumamoto, Japan), a
membrane-permeable Ca2?indicator, was loaded into the MF terminals
without severing the axons. The dye was injected locally into the stratum
lucidum, resulting in selective labeling of the mossy fibers. The fluores-
cence (excitation at 510–560 nm and monitoring above 580 nm) from the
area (?100 ?m diameter) containing the labeled terminals was measured
with a single photodiode (S2281–01; Hamamatsu Photonics, Hamamatsu,
Japan), while the field EPSPs were monitored simultaneously from the
area. The ?F/F value evoked by a single electrical stimulus was used as
a measure of [Ca2?]iincrease during an action potential. Subtraction of
the background fluorescence was not performed, because the fluores-
cence of unlabeled region of the slices at this wavelength was almost
negligible. No attempt was made to relate the ?F/F value to peak [Ca2?]i,
because our methods detect the fluorescence signals from the terminals
as well as the axons, and we could not estimate the relative contribution
to the total signals. The output of the photodiode was I–V converted,
amplified, and filtered at 500 Hz with an eight-pole Bessel filter (FLA-1;
Cygnus Technology, Delaware Water Gap, PA). The signal was then
digitized with a 12 bit analog-to-digital converter (Digidata 1200A; Axon
instruments, Foster City, CA) and acquired at 10 kHz using pClamp8
software (Axon Instruments). Data in the text and figures are expressed
as mean ? SEM (the number of experiments). Statistical analysis was
performed using the paired t test unless otherwise noted, and p ? 0.05
was accepted for statistical significance.
Measurement of fiber volley. The presynaptic fiber volley (FV) was
recorded in the presence of 10 ?M CNQX to avoid contamination of the
field EPSPs. The amplitude of FV was measured as a difference between
the initial positive and the following negative peaks. Field potential was
filtered at 2 kHz and digitized at 20–40 kHz for FV measurement. To
confirm that the responses surely reflect FV, 1 ?M TTX was applied at
the end of all experiments (see Figs. 1C, 2C).
Measurement of miniature EPSCs. Whole-cell recordings were made
from CA3 pyramidal neurons, and miniature EPSCs (mEPSCs) were
recorded at ?70 mV in the presence of 0.5 ?M tetrodotoxin and 100 ?M
picrotoxin (Kamiya and Ozawa, 1999). Patch pipettes were filled with an
internal solution (pH 7.2) containing the following (in mM): 150 Cs
gluconate, 0.2 EGTA, 8 NaCl, 10 HEPES, 2 Mg2?ATP, and 5 QX-314
(lidocaine N-ethyl bromide quaternary salt). The membrane currents
were filtered at 1 kHz and collected for 60 sec in each data point. The
mEPSCs (6 pA amplitude threshold) was analyzed off-line using Mini
Analysis Program 5.1 (Synaptosoft, Decatur, GA). No attempt was made
to group the events by the rise time. The Kolmogorov–Smirnov test was
used to assess the effects on amplitude and interevent interval.
Presynaptic Ca2?entry is unchanged by
MF-LTP expression
First, we examined whether stimulus-evoked presynaptic Ca2?
influx is modified during expression of MF-LTP. High-frequency
stimulation of MF (100 Hz for 1 sec) elicited sustained potenti-
ation of field EPSP amplitudes (195 ? 14% of control at 20 min
after tetanus; n ? 8) (Fig. 1A). In contrast, fluorescent signals
(FCa) recorded simultaneously did not change significantly (94 ?
2% of control) (Fig. 1B). Background fluorescence (F), reflecting
resting Ca2?level, was also not affected (97 ? 3% of control).
The lack of effect on FCamight not be attributable to saturation
of indicator, because raising external Ca2?to 3 mM (125% of 2.4
mM standard solution) enhanced FCasubstantially (119 ? 2% of
control; n ? 5). In separate experiments, we monitored presyn-
aptic FV in the presence of the AMPA receptor antagonist
CNQX (10 ?M), because a previous study demonstrated that
tetanic stimulation produces long-lasting change in presynaptic
excitability by assessing latency of FV (Mellor et al., 2002).
Changes in the FV amplitude are rather small (105 ? 1% of
control) at 20 min after tetanus (n ? 6) (Fig. 1C). These results
suggest that MF-LTP is not accompanied by a change in presyn-
aptic Ca2?dynamics within each terminal but is instead attrib-
utable to enhanced efficacy of exocytotic machinery downstream
from Ca2?influx. Then, we examined the mechanism responsible
for forskolin (FSK)-induced potentiation at this synapse, which
has been proposed to share common expression mechanisms with
tetanus-induced LTP (Weisskopf et al., 1994). Application of
FSK (50 ?M for 20 min) resulted in a gradual increase in field
EPSP amplitudes (480 ? 42% of the control value; n ? 6) (Fig.
2A). Simultaneously recorded FCawas increased by FSK (121 ?
Figure 1.
in presynaptic Ca2?entry. A, Amplitudes of field EPSP ( fEPSP) were
plotted against time. Tetanic stimulation (Tet; 100 Hz, 1 sec) was applied
at the time shown by the arrow. Representative traces are those recorded
before (control, thin trace) and 20 min after (LTP, thick trace) tetanic
stimulation. B, Presynaptic Ca2?transients recorded simultaneously
(FCa) were unchanged, whereas clear LTP was observed as in A. Appli-
cation of CNQX (10 ?M) did not decrease FCa, confirming that fluores-
cence signals were originated exclusively from presynaptic structures. C,
Time course of the presynaptic FV amplitude recorded in the presence of
10 ?M CNQX. The FV amplitude was decreased soon after the tetanus,
although it recovered afterward.
LTP at the MF–CA3 synapse is not accompanied by a change
Kamiya et al. • Ca2?-Independent Presynaptic Expression of MF-LTPJ. Neurosci., December 15, 2002, 22(24):10524–10528 10525
Page 3
4% of control) (Fig. 2B), whereas F value was not affected
significantly (96 ? 2% of control). FV recorded in the presence of
CNQX increased in amplitude by almost the same degree as FCa
(115 ? 3% of control; n ? 7; p ? 0.24) (Fig. 2C). Application of
50 ?M 1,9-dideoxyforskolin, an inactive analog of FSK, affected
neither field EPSP amplitude (103 ? 7% of control) nor FCa
(94 ? 5% of control; n ? 3). These results suggest that the
FSK-induced potentiation is accompanied by the increase in the
number of firing axons that explains the increase in FCaduring
application of FSK but is unlikely attributable to an increase in
action potential-driven Ca2?influx into the individual presynap-
tic terminals.
Enhancement of frequency, but not amplitude, of
miniature EPSCs during MF-LTP
To investigate changes in transmitter releasing machinery more
directly, we also examined the effect of tetanic stimulation of MF
on mEPSCs recorded from CA3 neurons (Jonas et al., 1993;
Kamiya and Ozawa, 1999). Some events displayed relatively slow
decay time course (Fig. 3A1, A2), possibly reflecting that kainate
as well as AMPA receptors partly contribute to mEPSCs in CA3
neurons (Cossart et al., 2002). After recording control data in the
presence of TTX, the TTX was removed from the perfusing
solution for 10 min, and then a high-frequency stimulation (100
Hz for 1 sec) was given (Fig. 3B). Substantial evoked MF re-
sponses were replenished at this time (data not shown). Soon
after the tetanus, TTX was added again, and 1 min records were
taken every 5 min thereafter. The increase in mEPSC frequency
was noted even 30 min after the tetanic stimulation (Fig. 3A1)
without significant changes in the distribution of the amplitudes
(Fig. 3A3). The cumulative amplitude histogram was not signifi-
cantly affected, whereas the cumulative plot of interevent intervals
showed a significant difference ( p ? 0.05; Kolmogorov–Smirnov
test) (Fig. 3A4). On average, mean frequency of mEPSCs increased
to 212 ? 50% of the control value, whereas mean amplitude was
little affected (104 ? 9% of control; n ? 14) (Fig. 3B).
The frequency of mEPSCs was also increased during the ap-
plication of 50 ?M FSK (Fig. 3C1) without significant changes in
the amplitude distribution (Fig. 3C2). The cumulative plot of
interevent intervals, but not of amplitude, was affected by FSK
( p ? 0.05; Kolmogorov–Smirnov test) (Fig. 3C3). On average,
mean frequency of mEPSCs increased to 211 ? 25% of the
control value, whereas mean amplitude was little affected (97 ?
5% of control; n ? 11) (Fig. 3D). Application of 50 ?M 1,9-
dideoxyforskolin affected neither mean frequency (104 ? 9% of
control) nor mean amplitude (101 ? 7% of control; n ? 6) of
mEPSCs. Because sustained elevation of basal Ca2?level within
the MF terminals was not accompanied by LTP expression (Re-
gehr and Tank, 1991) and we also did not observe significant
change in F value in this study, the enhancement of frequency of
mEPSCs strongly supports the notion that LTP and FSK-induced
potentiation was accompanied by enhancement of the release
machinery downstream from Ca2?entry. Taking all results to-
gether, we conclude that the expression mechanism of MF-LTP
does not involve an increase in stimulation-dependent Ca2?
influx into the terminals but is instead attributable to an increase
in the efficacy of downstream exocytotic processes.
Using fluorescence measurement of presynaptic Ca2?in mouse
hippocampal slices, we demonstrated here that MF-LTP is not
accompanied by a change in the presynaptic Ca2?transients, as
shown for LTP at the CA1 synapses (Wu and Saggau, 1994).
Instead, sustained increase in the efficacy of release machinery
was suggested by the findings that mean frequency, but not mean
amplitude, of mEPSCs was increased during MF-LTP.
Our results ruled out the possibility that activity-dependent
broadening of the presynaptic action potential and the subsequent
increase in presynaptic Ca2?influx (Geiger and Jonas, 2000) may
underlie the expression of MF-LTP. A previous study revealed
that sustained elevation of the basal Ca2?level within the termi-
nals does not occur during LTP at this synapse (Regehr and
Tank, 1991). Thus, MF-LTP does not involve any change in
presynaptic Ca2?dynamics. Rather, exocytotic machinery down-
stream from Ca2?influx is selectively upregulated, as suggested
by the mEPSC experiments in cultured hippocampal granule cells
(Tong et al., 1996) and by the neurochemical study using MF
synaptosomes (Lonart et al., 1998). Ca2?-independent expres-
sion mechanism of MF-LTP, as demonstrated in this study, is
rather unexpected in light of the recent findings showing that
presynaptic Ih(Mellor et al., 2002) or kainate autoreceptor (Con-
tractor et al., 2001; Lauri et al., 2001) (but see Nicoll et al., 2000)
is essential for MF-LTP, because activation of these channels
would depolarize MF terminals and affect action potential-driven
Ca2?entry processes by modulating voltage-dependent K?chan-
nels and/or Ca2?channels.
It should be mentioned that the very recent paper by Cheva-
leyre and Castillo (2002) reported strong evidence against the
hypothetical roles of Ihin MF-LTP. They found that organic Ih
blockers (ZD7288 and DK-AH269), which had been supposed to
Figure 2.
in Ca2?dynamics within MF terminals. A, Enhancement of fEPSPs
during application of 50 ?M FSK. B, Time course of FCain the same
experiments as in A. Representative traces are those recorded before
(control, thin trace) and 20 min after (FSK, thick trace) FSK application. C,
Time course of FV amplitudes. FV was increased in size by almost the
same degree as that of FCa, suggesting that FSK enhanced presynaptic
excitability but is not accompanied by an increase in Ca2?influx into the
individual terminals.
FSK-induced synaptic enhancement is independent of changes
10526 J. Neurosci., December 15, 2002, 22(24):10524–10528Kamiya et al. • Ca2?-Independent Presynaptic Expression of MF-LTP
Page 4
be selective for Ihchannels, exert a nonspecific action to suppress
MF synaptic transmission. They also performed "two-pathway"
experiments to get around this masking effect of the blockers and
clearly demonstrated that these blockers do not affect MF-LTP.
From these results, the authors also put forward their hypothesis
that MF-LTP results from a direct modification of the release
machinery (Castillo et al., 1997, 2002).
Because of the negative nature of the results in this study, one
may argue that saturation of the Ca2?indicator would mask the
changes in the Ca2?transients. However, we tried to minimize
this possible artifact by using the relatively low-affinity Ca2?
indicator rhod-2 (Minta et al., 1989) instead of the higher-affinity
dye fura-2. In fact, the signals increased substantially by several
conditions, e.g., application of phorbol ester (Honda et al., 2000),
paired stimuli at short intervals (Kamiya et al., 2002), or elevated
external Ca2?concentration (this study). We also paid attention
to load the dye at room temperature to reduce the compartmen-
talization into the mitochondria. As a result, the signal displays
monotonic decay after the peak (Kamiya and Ozawa, 1999; Ka-
miya et al., 2002), suggesting minimal contribution of the signal
originated from mitochondria or other organelles.
To examine the changes in the efficacy of release machinery, we
examined the mEPSCs recorded from CA3 neurons. Because we
cannot distinguish the origin of the observed minis (MF termi-
nals or the other presynaptic terminals making contact on CA3
neurons), contamination of those originated from non-MF inputs
might distort the present results in an unevaluated way. There-
fore, it must be emphasized that the effects of tetanic stimulation
or FSK might be somewhat underestimated, because these ma-
nipulations are expected to selectively affect minis originated
from MF terminals (Weisskopf et al., 1994). More importantly,
however, it certainly supports the notion that MF-LTP and FSK
potentiation are accompanied by enhanced efficacy of release
machinery at the MF terminals.
FV amplitude was increased by application of FSK but not by
LTP-inducing tetanic stimulation. These findings might be inter-
preted as follows. The excitability of MF axons is enhanced by
both manipulations via cAMP elevation in the MF terminals
(Mellor et al., 2002). Bath application of FSK would raise cAMP
levels in the whole population of MF terminals and thus increased
fiber volley amplitude by recruitment of surrounding subthreshold
fibers. In contrast, tetanic stimulation might elevate cAMP con-
centration only within the stimulated MF terminals and therefore
does not lead to increase in the number of stimulated axons.
Differential effects of tetanic stimulation and FSK on FV ampli-
tude would be important for answering the question of why FSK
caused robust enhancement of MF responses in knock-out mice
of Rab3A (Castillo et al., 1997), RIM1? (Castillo et al., 2002),
RI? and C?1isoforms of protein kinase A (Huang et al., 1995),
and type 1 adenylyl cyclase (Villacres et al., 1998) in which
tetanus-induced MF-LTP is absent. Our results highlight differ-
ential mechanisms responsible for FSK-induced enhancement
and tetanus LTP, and this difference may explain, at least in part,
why FSK potentiated MF synaptic transmission in those mutant
mice. It should be noted that FSK enhanced both FV and pre-
synaptic Ca2?transient to the same degree in the similar multi-
fiber recordings at the parallel fiber synapses in the cerebellum
Figure 3.
frequency of mEPSCs during MF-LTP
(A, B) and FSK-induced enhancement (C,
D). A1, Representative traces recorded
before (control) and 30 min after tetanic
(top) and averaged (bottom) traces of 10
consecutive mEPSCs. A3, Amplitude his-
tograms of miniature EPSCs recorded un-
der control conditions ( filled bars) and 30
min after tetanus (open bars). A4, Cumu-
lative probability plots of amplitudes (left)
and interevent intervals (right) of minia-
ture EPSCs for control (continuous line)
and LTP (dotted line) data. B, Averaged
time course of the mean frequency ( filled
circles) or amplitude (open circles) of
mEPSCs. Tetanic stimulation (Tet; 100
Hz, 1 sec) was applied at the time shown
by the arrow. TTX (0.5 ?M) was perfused
during the periods as indicated. C1, Rep-
resentative traces recorded before (con-
trol) and 20 min after FSK application
(FSK). C2, Amplitude histograms of min-
iature EPSCs in the absence ( filled bars)
and presence (open bars) of 50 ?M FSK.
C3, Cumulative probability plots of ampli-
tudes (left) and interevent intervals (right)
of miniature EPSCs for control (continu-
ous line) and FSK (dotted line) data. D,
Time course of the FSK effect on the
mean frequency ( filled circles) or ampli-
tude (open circles).
Long-lasting enhancement of
A2, Superimposed
Kamiya et al. • Ca2?-Independent Presynaptic Expression of MF-LTPJ. Neurosci., December 15, 2002, 22(24):10524–10528 10527
Page 5
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pocampal mossy fiber pathway: a review. Neuroscience 98:407–427.
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10528 J. Neurosci., December 15, 2002, 22(24):10524–10528Kamiya et al. • Ca2?-Independent Presynaptic Expression of MF-LTP


text:
Patience Edit
^Believe me, it works like a charm sometimes ;)--Omojuze (talk) 21:18, September 18, 2015 (UTC)
- Trust me, I'm the same way sometimes, as well >.< Just best not to rush and trust in fellow editors.--Omojuze (talk) 21:21, September 18, 2015 (UTC)
Re:Translation Edit
I see... Thank you for the tip. (^_^) --JouXIII (talk) 21:33, September 18, 2015 (UTC)
- 'sigh' Could you be so kind and explain with simple terms, how does translation template works?--JouXIII (talk) 22:16, September 18, 2015 (UTC)
Thank you Edit
Thank you! That will help a lot :] GodlyHades (talk) 21:27, November 20, 2015 (UTC)
Inojin lost to Arya Edit
It was in the Movie. 52:20 or something, around that time.
But yeah. The match didn't show, but it showed the title screen. The loser names blacks out, and the winner lights up.
GodlyHades (talk) 08:23, November 26, 2015 (UTC)
Sorry Edit
Sent it to you by mistake^^GodlyHades (talk) 08:33, November 26, 2015 (UTC)


text:
Soffe Girls' Soffe Dri Capris
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Key Specs:
- Fabric Content: 88% polyester, 12% spandex
- Inseam: 16 inches
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Comments about MJ Soffe Soffe Girls' Soffe Dri Capris:
Loved the style, but the fit was odd. Waistband too big for the fit of the legs, as well as short. So every time she bent over in them they fell down too far. Had to return, which was too bad because they're so cute.
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- Waist:
- Feels true to size
- Length:
- Feels true to length


text:
Narrow your search
HP's EliteBook Revolve 810 is a good first step toward a very portable business laptop-tablet hybrid, but lack of a killer battery life hurts it.
The Revolve XeMini Plus is an easy-to-use device that will deliver emergency juice on the go. You can't rely on the sun as your primary charging source, but the green features remain a nice benefit.
Ubisoft recently invested in MM-Company, the maker of a full-body VR chair called MMOne. Not only does this chair tilt 45 degrees left and right, it also lets the user do a full, seated flip while playing. Bring your fanciest barf bag!
Ashley and Khail talk about how YouTube Gaming might help Twitch, watch a crazy full-body VR machine that even simulates full vertical revolutions and wish they could visit an interactive exhibit in Tokyo featuring 60,000 LED lights.
Jessica Moreno has become the latest in a growing number of women to leave Reddit in the last several weeks, as the company looks to pivot on its content policy.
Alongside an expanded partner program, Nest has added the team behind the versatile Revolv hub to bolster its growing smart home platform.
With a new IFTTT channel, devices that work with Revolv will be able to sync up with the popular automation service, too.
The high-end smart hub is aiming to widen its appeal in the quest for a seamless smart home.
Leaked images reveal some great deals that may be in store from Dell this Black Friday.
Technically Incorrect: The Republican candidate's Twitter account retweets something that suggests Iowa corn affects the brain because there's too much of Monsanto's genetic engineering in it.


text:
Mona's Mehendi Ceremony in Kya Hua Tera Vaada
Added on 9/25/2012
By : tellybuzz
Overall Rating :
Rate Me... Rating Saved!
View : 16175 Comments : 4 Video Courtesy : www.india-forums.com
|Total Votes : 4
|luvumjht, AnGeL-BeAuTy, swethasyam08, jakther7
All bakvas,Mona said she was with Pradeep at the time of murder.that does not mean that she is residing with him .No court will force that they should live together.If you are ending the story joining Pradeep and Mona ,Please don't drag it ,we will be able to see another new serial
What Mehendi Ceremony ??? CVs r going to Mona-Pradeep together agin disgusting Go to hell CVs with Pradeep
wish u luck mona ... all d bst
thanks for sharing the Video!!
Wassup TV - Episode 59
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Press Conference of Kya Huaa Tera Vaada
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Comments :0


text:
'Journey' hoping for winning trip to Spike VGAs
LOS ANGELES (AP) — A pair of assassins, a horde of zombies and an intergalactic commander are facing off against a scarf-clad wanderer at Friday night's Spike Video Game Awards.
"Assassin's Creed III," ''Dishonored," ''The Walking Dead: The Game" and "Mass Effect 3" are competing to become game of the year against "Journey," the artsy downloadable title that leads the game of the year contenders with seven nominations in such categories as best graphics and original score.
"The Avengers" star and VGAs veteran Samuel L. Jackson is serving as host of the Spike gaming extravaganza. In honor of the show's 10th anniversary, previous VGAs hosts Zachary Levi, Snoop Lion, Jack Black and Neil Patrick Harris are set to appear with Jackson, who is hosting the show for the fourth time.
Celebrity presenters include Jessica Alba, Marlon Wayans, Adam Scott of "Parks and Recreation" and Norman Reedus and Steven Yeun of "The Walking Dead." Linkin Park, Tenacious D and composer Gustavo Santaolalla, who is creating music for the upcoming game "The Last of Us," are scheduled to perform.
The popular shoot-'em-up sequels "Borderlands 2" and "Halo 4" are tied overall for the most VGAs nods with eight. They're up for the best shooter trophy against "Call of Duty: Black Ops II" and "Max Payne 3."
This year's show will feature debut footage from such upcoming titles as "BioShock Infinite," ''Castlevania: Lords of Shadow 2," ''Tomb Raider" and "Gears of War: Judgment."
The VGAs will air live from Sony Picture Studios on both Spike and Xbox Live, the online service for Microsoft's Xbox 360 console. It's the first time the show will be streamed to game consoles.
Follow AP Entertainment Writer Derrik J. Lang on Twitter at http://www.twitter.com/derrikjlang.
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text:
CINCINNATI (AP) -- Procter & Gamble Co. says it has joined with BET Networks to create a television series supporting P&G's campaign targeting black women.
The inaugural episode of the new TV series features a segment that salute's first lady Michelle Obama. P&G also sponsored the BET Networks Inaugural Ball.
The Cincinnati-based consumer products company has said its "My Black is Beautiful" campaign combines marketing with forums meant to foster dialogue about black women and the way they are portrayed in popular culture.
The company says a recent P&G consumer survey showed that 90 percent of black women feel that Obama's role as first lady will have a positive impact on perceptions of black beauty.
The campaign is tied to brands including Olay skin care, Pantene shampoo and CoverGirl cosmetics.
(Copyright 2009 by The Associated Press. All Rights Reserved.)
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text:
Acer Veriton VZ2640G-UP2117X
Acer Veriton VZ2640G-UP2117X : Ports All of the ports in the back, including the one for the included AC adapter, are in a recessed shelf area. Since they are recessed and oriented vertically, the ports are hard to get to, particularly if you are plugging/unplugging the wired USB keyboard and mouse into the two USB 2.0 ports.
5 / 7


text:
As some of you may know my mother in law me have are problems I personally think shes a whiney, self absorbed, bitch but thats my personal opinion =]
Anyways my DF brother turns 13 the day after Thanksgiving... and we always send him something because his mother sucks and really doesnt do SHIT for his birthday!
Anyways DF called his mom last week and asked what to get him and she said some Zelda game...We were like okay...sweet!
Well she called back later that night and said to get some "Rocksmith" game cause she bought the Zelda game...So I go to the store the next day to pick it up and its like 84$!!!! PLUS we would still have to mail it...I told DF that we just cannot do that...while we have the money thats just outrageous for us to spend that when we still have baby stuff to get and Thanksgiving food to buy...and he agreed. He then asked how much the Zelda game was and that one turned out to only be 40$ which totally explains why she bought that one and left the other one for us.
So MIL callsĀther otherĀnight and asks if we have sent the present and DF tells her no not yet...so she responds "if its not going to be here by his fucking birthday dont bother sending a present" OKAY BITCH CHILL THE FUCK OUT! So anyways that pissed me off...
So I go to Target and buy the kid a 50 dollar gift card so he can go buy his own game or use that plus some bday money to buy rocksmith...
WELLL DF brother calls him last night in tears because he found the card we had sent opened in his moms bedside drawer and saw the empty Target giftcard thing so he asked her about it and she told him "well your dad hasnt paid fucking child support so I used the gift card for things we needed around the house"
OMGGGGGGG I am so fkn pissed! I cant believe she did that! She used our birthday giftcard for him to buy shit for herself or for around the house!!!!
DF told brother he would call his mom tonight...this could get ugly!


text:
So I'm in need of a bit of guidance before I go talk to my adviser for school.
I'm awful in tests. I literally have panic attacks before each test and hyperventilate (this also includes anxieties a week before where I lose hair, fingernails, have insomnia that only lets me have about three hours or less of sleep every two days, and get really sick). During the tests I cannot remember the material or I'm so stressed out I can't calm myself down to think and do well. None of the "relieve your stress" test workshops have helped (in fact they made it worse....) and it's getting to the point where I'm beginning to doubt that I can make it in college.
For example in my language class (which I'm proficient in) my prof pulled me aside to ask me what was wrong. I've failed every single test. She did some assessments with me and I know the material, she said I'm one of her best students but my test scores are bad. (Several other teachers have also made these remarks.) I've always been like this with any tests but some I can manage to make it through fairly well (Biology is an example of this, I can still have my melt downs and get a good grade like a C or above in the test. I figure it's because that subject just clicks with me more easily than the others. The stress is still there though.)
I don't get stressed in work or emergency situations, just when taking a test. I'm trying to figure out ways to calm down but short of taking Dramamine to ease my symptoms (as Doctors suggested) I'm still a mental wreck. I have an appointment with my adviser about my schedule and I'm wondering what my options are? I'm not trying to get out of tests at all, I'm just trying to find a way to survive them especially since they're the majority of my grade. It makes this hard to convince anyone that I'm telling the truth because I don't have any learning disabilities or other influences. Anyone else had this problem?
I'm in the process of scheduling an appointment with a psychiatrist to see what might be bugging me, I'm hedging my bets on bad experiences with tests and teachers; but I really am not keen in experimenting with anxiety meds or messing with my brain chemistry (especially since there's a history on both sides of my family with dyslexia, schizophrenia, IED, bipolar disorder, and a few others.) And my adviser hasn't been helping by telling me through phone calls/emails every day to shape up or ship out.
Anyone got any ideas or maybe had this experience? I had one therapist a couple of years ago suggest that I might have an issue going on with taking tests (similar to dyslexia) however I'd need to see a psychiatrist and see where that led. I guess what's most upsetting is my math prof (aka the class I'm doing the worst in because of the amount of tests) accused me of faking and trying to use excuses for me not studying. I study every night for about six hours for that class. The tests just get me and bring me down....
Thanks in advance.


text:
Elm Street closed Thursday and Friday
MONTPELIER A section of Elm Street will be closed both Thursday and Friday this week, to allow for repairs to be made to a brick building at the corner of Elm and School streets, city officials announced.
A problem with the brick facade of the building, which houses the Uncommon Market on the ground floor, was discovered recently when the city was embarking on a sidewalk improvement project. Due to the risk of falling bricks, the sidewalk project had to be postponed until the structural issue was resolved.
City officials had already announced that starting tomorrow and continuing through Friday, Elm Street would be closed to all motor vehicle traffic between the intersection of Langdon Street and the Elm Street/School Street intersection. All businesses will remain open during construction including the Uncommon Market. If deemed safe, the street will be open during the evening, non-work hours of the project.
Information on the project is also available at the City of Montpeliers website, www.montpelier-vt.org. Questions or concerns can be directed to Christopher Lumbra, building inspector, at 223-9506 or by email at firstname.lastname@example.com IN This Just In
ATLANTA — Bernie Sanders acknowledges that he needs more support from black voters to... Full Story
The following is a sampling of calls to Montpelier police in recent days.
Nov. Full Story
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- CambodiaAgricultureFunding via VisionFund Cambodia
Kong GroupCambodiaAgricultureFunding via KREDIT Ltd.
SinatCambodiaAgricultureFunding via Hattha Kaksekar Limited (HKL), a partner of Save the Children
Mrs. Pring Din Village Bank Group
Mrs. Pring D. is the village bank president. She is 48 years old and the mother of three children who are studying at the local public school.
Mrs. Pring D. is a farmer who owns a plot of land on which she cultivates rice, and her husband, Mr. Saorum K., is a construction laborer.
Mrs. Pring D. now has an obstacle because this is the harvesting season but she does not have enough money to hire laborers to harvest her rice. Thus, she decided to ask for a second loan to hire laborers to harvest her rice.
Additional Information
About AMKAngkor Microfinance Kampuchea (AMK) is a leading microfinance institution in Cambodia with a wide reach of operations. AMK works with over 6,000 villages and serves clients in every Cambodian province. With an average loan size of US$115, AMK's focus is to provide credit and savings products to the very poor in rural areas. For more information, please visit AMK's website.
This is a Group Loan
In a group loan, each member of the group receives an individual loan but is part of a larger group of individuals. The group is there to provide support to the members and to provide a system of peer pressure, but groups may or may not be formally bound by a group guarantee. In cases where there is a group guarantee, members of the group are responsible for paying back the loans of their fellow group members in the case of delinquency or default.
Kiva's Field Partners typically feature one borrower from a group. The loan description, sector, and other attributes for a group loan profile are determined by the featured borrower's loan. The other members of the group are not required to use their loans for the same purpose.
About Cambodia
45View loans »
Success!! The loan was 100% repaid
- Repayment Term
- 14 months (Additional Information)
- Repayment Schedule
- Monthly
- Pre-Disbursed:
- Dec 13, 2009
- Listed
- Jan 12, 2010
- Currency Exchange Loss:
- Possible
- Ended:
- Jul 29, 2011


text:
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Spinach and Beef Lasagna
Pizza Lasagna
Easy Caprese Pizza Bake
Three-Cheese Beef Pasta Shells
Cheesy Florentine Biscuit Cups
Italian Zucchini Crescent Pie
With a nod to the Greek Isles, shrimp and penne pasta are punctuated with spinach, olive oil, feta cheese and ripe olives in this succulent dish.
For a more authentic Greek version, use pitted kalamata olives in place of the more common variety.
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November 29, 2015
Washington (AP) Hillary Rodham Clinton's once-imposing lead among democratic superdelegates has all but vanished, as Barack Obama continues to pick up support.
Six of them endorsed Obama for president today, including congressman Donald Payne of New Jersey. The congressional black caucus member had been supporting Clinton, but he says "after careful consideration," he's concluded that Obama "can best bring
about the change" that the country wants and needs.
On the eve of the primary season, Clinton had a lead of more than 100 superdelegates. Today, Obama has narrowed the gap to two and a-half.
Obama has been gaining strength since Tuesday, when he scored a convincing victory in north carolina's primary and Clinton took Indiana by only a narrow margin.
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The most amazing Christmas card you'll see this year? Probably. Among the most shameless plugs of all time? Definitely.
The Holderness family of Raleigh, N.C., are the brains behind the video Christmas card Christmas Jammies, which has gone viral. Local news anchor Penn Holderness, his wife, Kim, and their two kids, Lola and Penn Charles, rap about their awesome 2013 (to Will Smith's 'Miami') in matching ...