text:
Politics Counts
Foreign Policy
The whole industry is not in trouble only three companies. It should be illegal to help some while hurting others.
I disagree that Detroit's health is tied to the "overall health of our economy." It's definitely tied to Michigan's health, but doesn't have much impact overall. Bankruptcy will solve the most pressing problems: too many concessions to the auto union's strong-armed tactics, and poor design and innovativeness of U.S. made cars. Cutting costs, including gold-plated retiree benefits, and shedding extraneous jobs are what's needed for the long-term health of the domestic industry.
Your point is accurate that the car companies have failed to make a product at a profit for too long. Poor Govt policies and market demands led to the big gas guzzling machines of the past. The sad part is that if our government ignores the requests for liquidity, it appears likely that dealers, suppliers, and workers -- 10s of thousands lose their jobs, their benefits, and that wouldn't help the economy. Avoiding depressions is about the govt pumping money when the system failed. All those who practiced 'socially irresponsible captitalism' should contribute/invest their gains to help bring us to a better place.
"B _ _ _ S _ _ _; if you belive this letter of protecting the US Tax Payer... then of course you have to believe in... CNB's talking dog "Craming Cramer" and the US Government "Tooth Fairy"! "Wake the Hell up America... wake the hell up"!
Bloomberg News Sues the Fed
Econ Blog should have consulted with the Oz on this one.
The Oz has said repeat ably over the last 2 years that this information lies in the Highest Seat in Washington… "Ejective Privilege"! Bloomberg News and the US Fed's Funding Fund source… the US Tax Payers have no chance in hell of obtaining this privileged information… YOU THINK! Only by an act of Congress Law can they get their hands on this "House" of smoke and mirrors, lies and deceit that the Government has doled out to the public… just more of the same…
I don't blame the federal government for Detroit's ills. Besides trying to raise fuel-efficiency standards, I'm not aware of one policy that has contributed directly to their problems. If it were that simple, it wouldn't be just the domestic auto makers that are suffering and close to bankruptcy.
Nancy Pelosi
Speaker of the House
Harry Reid
Senate Majority Leader
Will you send the same letter when GE and others comes-a' knocking also... hum, get a life and go back on the street beging for US Tax Payers votes, I can't wait to see the votes you all will get when up for re-election again... YOU THINK...
Best regards and by the way good luck your going to need (*IT) come election day... you think (green cars)... give me a break will ya'!
The OZ...
Hey, I'm a realtor who is starving to death because the dems botched up the mortgage process in order to help losers. Where's my bail-out? And btw, Nancy, in your letter ending with best regards, regards should be capitalized, as are all words in the closing of a letter... sheesh...doesn't she know ANTYTHING?
To 3:03 pm... no problem on Nancy's spelling... you see she didn't write (*IT)! Useless Paulson wrote (*IT) to himself... you think! The smoking lamp is in lit, come Monday morning on Walless Street!
Nov. 8, 2008
Governor Jennifer M. Granholm
P.O. Box 30013
Lansing, Michigan 48909
Re: Creating 900,000 good paying jobs
Dear Governor Granholm:
Addressing both our energy, economic and environmental needs is one of the great challenges of our time. The United States needs to create hundreds of thousands of jobs as well as energy that is both cleaner and more affordable. With vision and smart steps today, the United States can do these and take advantage of the financial crisis to address national security, global warming, instability in oil markets and the rising cost of other energy resources. If we are smart we will see that the increasing demand for alternative energy and energy-saving products and services is at an all time high and is rising and tha
I have a plan that I believe with minimal federal government support and financing could begin creating 900,000 good paying jobs in the United States within a matter of a few months. About 300,000 of these would be distributed among the 3,000 or so counties all across the country. These jobs would be in manufacturing, administration and installation of renewable energy products for residential and smaller business entities in those counties. An additional 300,000 would be created in midsized companies among the 50 states who are downsized or will be downsizing. These firms will become involved in the manufacture of steel intensive renewable energy products for larger firms and institutions. Finally an additional 300,000 or so manufacturing jobs would eventually be made available by the big
Creating these 900,000 or so good paying jobs would also provide another boost to the economy in reducing the total number of other jobs lost due to lack of work. Many of these would be in the trucking and steel industry as making and hauling of these materials. Both steel making and hauling would be needed to bring supplies to those manufacturing locations and to deliver the various alternative energy products to end users.
Les Blevins, AAEC
http://aaecorp.com – firstname.lastname@example.com
I thnk we are getting dupped by the media on job loss. The 1.2 million extra jobs that makes parts for GM, etc. can now make parts for Honda, Toyota, etc. Gm needs to prove to the world a business plan that shows their recovery to profitablilty before the Gov. gives them money.
Everyone knows it's the unions that made the Big Three non-competitive. If Pelosi and Reid were serious about restoring the Big Three to health, they should pull the plug on the UAW. But will that happen? No. Instead, Pelosi and Reid are doing this to bail out the unions, which caused the mess in the first place. And it's all being done at the expense of the taxpayers. But of course Pelosi and Reid will want only the top 5% percent of the people to pay taxes. Yes, let's have the top 5% support the other 95%. "From each according to his ability, to each according to his needs." Where have I heard that before?
The financial crisis is just a smoke screen -- the U.S. auto industry has been losing money for years. The truth is that their business model simply does not work and must either be allowed to fail or completely overhauled to negate the effects of the UAW and legacy healthcare/pension expenses. That is the only way they can compete in a global market. Propping them up with bailouts (with money we don't have) will only prolong the duration their death throes. Any realistic solution will result in a lot of pain for a lot of people -- that is the nature of bitter medicine to cure this disase that is our economy.
Bailout for the Big Three? My partner and I run a company with 27 employees. If we made the same bad decisions that the Big Three made in Detroit we would loose our houses and our employees there jobs. We have no "Bailout option." This actually forces us to produce a product that sells and be resposible (Ourselves resposible, not the taxpayers) for the decisions that we make. I say let them die! It's ecomonic darwinism! Out of there ashes will come new companies to fill the gap! P.S. SOmetime obituaries have to be written. I say it's time for the possibility of a R.I.P. for Ford, GM or Chrysler!
Yay more corporate welfare! If the entire industry was on the verge of dying, but no it just happens to be 3 companies who's products consumers don't want to buy. How does investing our tax dollars in them make sense?
Federal goverment bialed out wall street like financial and insurance (AIG 125 billion)industries who created this mess.
I strongly feel that federal government need to help real economy industries like BIG 3. which creates employment not only in michigan , ohio and all across USA (dealers, supplierse.tc. )
Auto Industry invests so much in advanced research and also so many suppliers (like steel, electronics, plastic e.tc.) depend on survival of auto industry
Pelosi and Reid championed the bank bailout. Now that they have helped Bush and crew rip the taxpayers off one more time, they are trying to pass the blame for their ineptitude. Perhaps the people will wake up in two years and not re-elect these two.
The people who own the Fed are running the Treasury. Trying to get money from the banks once they have it is like trying to get a quarter pounder away from a grizzly bear.
The best way to solve the problem is to print more Franklins, give them to the middle and lower classes, and wait for them to trickle it up. I figure it'll take about $50k per family; they'll decide who wins and who loses by where they spend the money. (I'd spend mine on a little farm where I can grow food, and wait for Adam's invisible hand to show itself...ha!)
There is nothing the American automotive industry has done since the early 70's to ward off debilating competition globally. GM and Ford certain have a presence in Europe and S,America but they have not accomplished a reasonable energy efficient car or a manufacturing culture that insured a top notch product at all levels.
Capitalism ? are we not the strongest proponets of a capitalist free trade economy? I guess socialism is right... individual prmomotion leads to mass decline....
Let the industry rebuild itself and those that depend on it for their living... hell the rest of us are responsible for our own living...
Any way dollar is getting stronger compared to euro e.tc. Instead of giving to wall street, print more money and give 50k for each family and this will help the economy
Oh, and let's not forget to create opportunities for the CEO's to organize. Heaven knows they should be granted collective bargaining rights within a the free market system. Socialize their salaries and privatize their rights under law. After all. everyone knows it's the unions that caused every problem with the free market. I mean why should the little people be allowed a decent living, education for the kids, and a little rest during retirement. Let them eat possum!
I have an 8 year old GM car that I gave to my son in college. It has consistently had something go wrong with it since I bought it new. I feel like I have done my bit for GM and I don't want another GM car nor do I want to bail them out.
Building cars that no one wants is like that bridge to no where. Let us mourn them and move on to a better auto industry.
Pelosi and Reid huh? That's a 9 on the stink richter scale, to officially become 10 when Obama takes office.
Reward Detroit for NOT making a car more people would rather buy than a Civic, Corolla, Accord, or Camry -- new and six-years used?
Unions are not the problem. If in the last ten years more people wanted to buy a Ford, GM, or Chrysler vehicle than Honda or Toyota, there would be no problem.
We dont make anything else in the USA why should we keep making cars,
we consume we do not produce, we used to produce more than we consumed
in the 50s and we had a great economy under Truman,
now we produce nothing and we have a horrible economy,and it will
continue to be horrible until we rebuild our Industrial base, failing
to do so will lead to the Russians,Chinese and Middle East wealth will
dominate the world financial arena
Made in the USA used to mean something until that is fixed we are
No bailing out of auto industry results about 3-4 million jobs loses in about 6 months
After that other industries follow with more job loses
Lastly, let us look to the Chicago School for further free market guidance. (Smith's prose is a bit archaic, don't you think?) The five per cent (actually, now that CHANGE is coming, it should be in caps, as, THE FIVE PER CENT), who'll be paying their way for a change, will soon determine it to be in their economic interest to haul ass and seek a new society not yet bait shy. Don't let the doorknob hit you in the ass on the way out....
Ah yes, this ones very easy to understand. Bloated, out of date auto companies start crying big tears when they see billions available from the taxpayers. We will make the weak weaker by bailing them out. By the way, a local Big Three truck dealer is offering zero percent financing for 72 months to buyers. Bailout money will go to pay for the loss on the sales. Taxpayers would be subsidising lousy mpg transporation and blind long range vision.
Let's Hope the new guy invests in domestic industries like infrastructure e.t.c unlike the current guy who invests in Iraq
Oh yeah, forgot this previously: Pelosi and Reid should make sure auto dealerships -- the ones out to sell cars at the highest possible cost to every individual that walks in -- are taken care of too.
Steel industry gone !!!
Electornic Industry Gone !!!
IT is going !!!
Manufacturing disappearing !!
Farming outsourced !!!
Only industry still left is service industry (can't afford to buy any thing)
We need to invest in america
The real stinker to all this is that four years from now 99% of all posting here may go cyclically lame in da brain and vote yet AGAIN for one of the two major candidates in the 2012 presidential primaries.
Hope I'm wrong on that.
When will enough finally become enough for 51%-plus?
I invested my '08 primary vote with Ron Paul. That didn't work so I tried to crack-back block Pelosi Reid et al by voting McCain in the general election. That didn't work either.
Seriously, start thinking credible third party now, so we all don't reassemble here again in four years to complain about what we could have prevented.
Sure, let's use taxpayer money to bail out badly-run companies. Doesn't matter to Pelosi or Reid - it's not their money. I love it. Good companies don't need bailouts. Bad companies will get them if Pelosi and Reid get their way. Better for the auto companies to go into bankruptcy so they can clean up their books.
Chapter 11 would allow the auto industry to renegotiate all contracts. But is the cost structure the real problem here? The problem is demand that has evaporated because of the ever expanding recession. You have to fix consumer balance sheets to get out of this fix. I heard a proposal by a real estate mogul that made a lot of sense. Essentially, the gov would facilitate mark to market for any mortgage holder that wanted it and their bank agreed. In return the gov and the bank would get a share in the future appreciation of the house. Creating budget room in individual balance sheets is what will get the economy back on track. Of course I know this smacks of "socialism" but it could be a way out. I just don't think that have "tough" this out at the cost of the livelihoods of millions.
It is Gov't Policies, like CAFE standards that prevent outsourcing production overseas, union activism, and the anamoly of the US Health Care system vis-a-vis Global Healthcare that created the problems for Detroit. It is only fair that the US Goverment place the US Auto Industry on a level playing feild with Foreign Manufacturer's by providing Assistance Directly that Foreign Governments provide both directly and indirectly.
The Democrats want to push big auto troubles onto Republicans:
"The GOP badly implemented taxpayer resources--it's another of President Bush's secret conspiracies!"
The Democrats are painted into a tight corner.
They forgot crude propaganda and crass ideology are still propaganda and ideology.
God bless America and the civilization of American people--solid as a rock.
The Big three created their own problem. It's simple build cars that customers want to buy. Even the big three employees don't even buy their own products. Go figure. Let them go under the capital market will innovation and new opportunies for the unemployed.
Please don't bail them out!!
hey if obama thinks this is a good idea i think we should trust him. he has access to info we dont and he wouldnt be pres. if he didnt know better
The Governor of Michigan,Ohio and the President of the UAW have declared war on the Republican Party.
No bail out will work until they can answer one simple question.
Why would any normal Republican buy an American/ UAW made car.?
dont be negative obama would not support this if the taxpayer was at risk
if the ONE thinks this is the way to go then please step aside so the plan can commence
The auto makers of detroit have to suffer, the government can't keep bailing them out. Sure the government bailed out a few banks, but they also let the really bad ones fail. Something radical has to be done with the automakers, they are inefficient and they will continue to be as long as the government keeps trying to help them.
So much for CHANGE. Clinton attack dog gets the Chief of Staff position. Here come the first paybacks: UAW gets their employer bailed out for supporting Obama. This is turning out to be a bad joke quicker than I thought. All of the high tax, high spending limit, failed state will be lining up at the trough next (need I mention that those are all blue states?). Failed business strategies paid off by the taxpayers. I'm glad I drive a Volvo and a Toyota and don't live in California.
terry if the ONE deems it best then it is best
barack wannabe open your eyes
The US big 3 automakers, and GM in particular, are incompetent and intransigient. They didn't see the rise in fuel prices (amazing), they didn't switch to smaller more fuel efficient cars and instead they spent their time and money lobbying for CAFE exceptions and deferrals. They seem to think that government loans, concessions and the like are part of their business cycle. Lets not reward their incomopetence. Their demise is invevitable. Let them die a natural death rather than throwing money at them and watching the money and the companies wither away.
my eyes are open the second coming has arrived
Now... now... now don't lose focus of the targets here; higher wages, more emploment, beter cost of living, money in the bank, happy days are here again for management... (Washington, Wall Street and the big (3))... screw the the eye sockets out of the damn 66.6% of the US Tax Payers base, come on down GE, what's behind door number (3)? "WHO... else want's in?"
Our government is a joke, and a bad one at that!
frustrated if you voted for the one you will be rewarded
Talk about spreading around the wealth, with this bail out of the Big (?)... of course upper management can aford a higher tax rate... YOU THINK!
auto aid will happen but how will they hide the money they will soon give to acorn
To survive, automakers are pressing Washington for $50 billion in low-interest loans on top of $25 billion already approved to build more fuel-efficient vehicles. The $25 billion, though, is gummed up in Energy Department regulations and may not be available until next year.
The industry's path to cliff's edge is a complex one that even critics say is intertwined with government fuel economy and safety regulations and the United Auto Workers union.
The demise started in the 80s when Toyota Motor Corp. and Honda Motor Co. mastered building reliable and efficient cars while the Detroit Three lagged behind.
mr lion - your cynicism is appalling obama got individual donations he is not controlled by corp america
Yea.. right, and the "Flying Monkey" on CNBC just flew up you A _ _!
hide the $ obama would not agree if it did not benefit the taxpayer he already said that
How about an independent audit of each of the auto makers BEFORE any more taxpayer money is tossed down the drain - starting with off-shore accounts and off-shore supply companies controlled by them ? These jokers had years to change their bad management and production methods but chose instead to pad their fat golden parachutes and profit margins. The Democrats need some psychiatric analysis if they think the average US Joe taxpayer is going to support another blind bailout. Let the BIG 3 face the consequences of their bad decisions just like the rest of businesses in America.
Then I would assume... the same monkey visted him before the election also!
tinker bell - your disrespect for the ONE is sickening
red hat you are as disrespectful as tinker bell
red hat you are not calling obama a monkey are you
To 10:15 pm, good insight on a positive thought process... will (*IT) work... hell no, you the 66.6% are not in control of the tv yet... you are still in the twilight zone!
Jeeeee, and all this time I thought "all the rest of the bussinesses" were banks... hum! Now you got me... thinking... YOU THINK... NOT!
all you people attack because he is a negro remember pelosi and reid are white
obama defender you seem like a zealot
not a zealot but i do no with the ONE in charge we will get what we deserve
defender you are out of control he lies and you support it
granville he is truly our savior
Gov't should bail all the citizen of this country. I work hard, pay mortgage, tax, and all of my debts. I am work 50 to 60 hrs weeks to take care of my two kids and no complaint. It is not fair for me( taxpayer) to bail all the executive at BANK, BIG THREE and ALL people that live beyond their mean. Why don't gov't bail me out too. We all need $$$. B...S...
Total B...S...!
granville you are a hater and you will be left behind when barack delivers
Pardon my French... but I have to... cerche' la fem!
Independent you should work harder. Mr. Obama worked harder than anyone and if he feels the big 3 need help then he will approve it.
B S do you mean cherche la femme ?
Duke and B S why dont you talk english if you a making some kind of comment about the pres-elect have the guts to say it in english
oboma pretender if you had your GED you wouldnt talk the way you do. hopefully the school tax credit will enable you to attain the skills to move from fries to drinks
when you say let the dealers fail because they overcharge evceryone that comes thought there door. what about the young people who are employeed, washing cars answering phones9while attending college), being trained as technicians, etc..., when they lose their jobs and can no longer shop anywhere, go to the movies, eat at restaraunts, etc... then all those other enitites will die, all of the suppliers will cut back and then their ex-employee's will no longer shop, go to the movies etc. everyone forgets that the auto industry is like a tapeworm it is in every part of the economy, and if you kill it, then you kill the entire economy......duh
ok ok
Wow. I want an appointment with Pelosi. Maybe I can get some money, too.
Paulson should not trust these 2 politicians. These 2 just want to unload responsibility to him. In case it doesn't work, Paulson is the one to blame.
the dems are making a big mistake by throwing their lot in with saving the auto industry.
They're just postponing the inevitable by keeeping the stockholders of GM Ford & Chrysler in the game.
If they want the jobs to be around, they'll have to participate in a quickie bankruptcy which gets rid of all shareholders, gives the creditors the new equity, and restructures labor's claims
otherwise, they're all just wasting taxpayer money which can be used far more effectively other places.
How's this for a simple solution? Instead of arguing amongst ourselves who should be eligible for the free ''bailout'' money, why not just have the government bailout out the entire United States at one time? Pay off all corporate credit lines, corporate debt, individual credit cards, car loans, education loans and your Blockbuster accounts. This way the entire U.S. will be debt free and we'll all live happily everafter in Cinderella land. Apparently money is available and free so why create disession amongst citizens? What a joke !! Bring out the Jack and let's celebrate. Incidentally does anyone have the government ''bailout application'' so I can apply?
It would be only reasonable diligence, if we are going to spend money - whether or bailing out auto companies or others - that we understand where this money goes and direct it appropriately. The small matter of union-related issues may have slipped the minds of Ms. Pelosi and colleagues. Perhaps ... before making requests of the Secretary of the Treasury ... researching how to direct money to the place it will help the most (and NOT into the pockets of unions) would be prudent and certainly would demonstrate fiscal responsibility that, at this point, seems to be lacking in our senatorial leadership.
wayne you are inane. if mr. obama thought this was the answer it would be done
Do I hear Obama administration, albeit voiced by Govenor for Michigan on Bloomberg mulling an industrial policy ?
It sure is a capitalist irony that the prerequisite to receive a bailout is failure!An auto industry bailout is but another bandaid applied to a gangrenous injury without addressing and moderating the legacy payments. It's either pain for the legacy recipients now or pain for them and many others later. What's needed is an amputation, not a bandaid.
Wow. No one understands the Constitution, so we debate illegal and irrelevant smokescreens of action by our "government". The government has NO Constitutional authority to intervene in the marketplace. Period. It is NOT government's role to "create jobs". It is NOT government's role to bail out people and companies that make stupid mistakes that cause them great financial pain. The more elected "representatives" intervene, the more they distort the marketplace, and the more pain that is ultimately caused by that intervention. Two things: read the Constitution which defines the LIMITED role of government...and read history, which illustrates that intervention ALWAYS results in calamity for citizens. THEN get into a meaningful vs a distracting debate/discussion.
Federal regulations require auto manufacturers to have a percentage of their products meeting certain pricing and fuel standards though they are not in high demand. The big SUVs sold in recent year, but were above the pricing and well below the fuel requirements; let's force them to make smaller, more affordable, more dangerous, and of course, fuel efficient cars.
We comprehend the need help the airlines; without them business essentially stops. Infusing capital in the banking system allows for short term loans, which meet payroll and operating expenses, etc.
To bail-out flawed business models that have been subjugated by big labor is absurd. This behavior by the congress only rewards poor business practices buy the auto industry and allows the unions to continue to harangue a
Federal regulations require auto manufacturers to have a percentage of their products meeting certain pricing and fuel standards though they are not in high demand. The big SUVs sold in recent year, but were above the pricing and well below the fuel requirements; let's force them to make smaller, more affordable, more dangerous, and of course, fuel efficient cars.
We comprehend the need help the airlines; without them business essentially stops. Infusing capital in the banking system allows for short term loans, which meet payroll and operating expenses, etc.
To bail-out flawed business models that have been subjugated by big labor is absurd. This behavior by the congress only rewards poor business practices buy the auto industry and allows the unions to continue to harangue.
to all if the ONE thinks the bailout is correct then he will he is the second coming
At one time the United States had many auto makers. Ford and General Motors bought or put all of them out of business and made a conglomerate of three auto makers. They are now failed and no amount of money will save them.
The Japanese and other so called foreign companies are building cars here. Invest your money in Honda and Toyota stock. Get a job building cars that people want.
If Americans own the stock and work at the plants then they are American companies.
If you lose your job you can move to India and work in a call center. Then we will be able to understand the directions.
Robert J. Lanier
Black Bart Roberts
Communism like this is not the reason I signed up for the military.
The OZ News Hour: Nov 9 200ATE (13:30 hrs);
On the future USA economic outlook press release, The OZ said deflationary risks are now greater than inflationary risks and have been gaining Depressionary status for quite some time now. With the financial crisis affecting both advanced and emerging economies, both sets of countries, he added, are "in the same boat", which is taking on more debt as we speak and show no true signs of "Life Boats" on board or on the rising tide of US Debt… as of yet. I see no end in sight as the Global Abyss sucks up the ever growing (US Debt) (US Tax Payer Funded) of a... "Never ending (Equity Horror) story"… of greed, deceit and smoke and mirrors coming out of Washington and Wall Street." He continued to repeat time after time... March 2009 is too... late!
GM, Ford, and Chrysler should be allowed to fail. It is not the job of government to dole out largesse from the public treasury to businesses that repeatedly lose large amounts of money, so as to enable them to continue to do so.
The American economic system works because people who repeatedly make large, costly mistakes, have capital taken away from them and given to competitors who didn't make those mistakes.
If the government follows Pelosi's lead, we'll be left with more and more of our resources devoted to the least productive enterprises.
Automakers are as much a victim of the banking meltdown as the banks. No loans means no cars sold. Think about this. If Toyota was in trouble do you think the Japanese gov would let them fail? Are those that say let them fail willing to find up to 1 million new jobs? Until consumer balance sheets get straightened out, the auto companies are going to be on life support. But as Yoda would say, "saving them you must"
No 2nd Bail Out for these auto makers! It's not the tax payer's responsibility! BTW, these companies already received a whopping 25B, and they want more! These CEO's should take a pay cut (no supplemental payments either) if they really want to help their employees then, do the best thing! Spend what they have wisely....
Obama ran his whole campaign on change and yet we are left with the likes of Pelosi and Reid. There will be no change until they step down from their leadership positions. That will signal real change.
Reid & Pelosi can wait a couple of months, then the new president can help any business or pardon anyone he likes. He has the power.
Shouldn't have any problems.
Mr. Al Gore can be of great help to the new president.
"We are writing" is a brilliant way to start a letter. Lot's of thought went into that part.
uncle larry your cynicism is appalling the ONE is for the people. LONG LIVE OUR SAVIOR!!!
Listen up! The Pelosi-Reid Relief truck has arrived. Please form an orderly line with the neediest companies at the head, followed by the rest in descending order of need.
appalledanddismayed, automakers are a victim of pandering to the unions, plain and simple. They chose to deal with the devil. They should now sleep in the bed they made, and leave the rest of us out of it.
One million jobs lost is a huge stretch. You're assuming all 3 companies will choose to liquidate (Chap 7). You're also assuming all million employees don't have other marketable skills. If that is indeed true, they deserve their fate.
Instead of giving $50 BILLION of taxpayer money to a destined-to-fail American auto industry (meaning that the taxpayer will never, ever be repaid), why does not Congress offer a $5,000 coupon to the next 1 million Americans citizens (not corporations or rental car companies) who go into an American car dealership and who purchase a Detroit-made car? The only question would be: are there 1 million Americans who would take Congress up on such an offer and buy an American car?
Planning under way for Obama holiday
The Capital-Journal
Published Sunday, November 09, 2008
Plans are being made to promote a national holiday for Barack Obama, who will become the nation's 44th president when he takes the oath of office Jan. 20.
"Yes We Can" planning rallies will be at 7 a.m. and 7 p.m. every Tuesday at the downtown McDonald's restaurant, 1100 Kansas Ave., until Jan. 13. The goals are to secure a national holiday in Obama's honor, to organize celebrations around his inauguration and to celebrate the 200th birthday of President Abraham Lincoln, who was born on Feb. 12 1809.
there should be 2 holidays one on 1/20 and the other on his birthday. this man is the greatest figure of our time and possibly all of history
Whops, my math was wrong. A $5,000 coupon directly to taxpayers would purchase 10 million cars for $50 billion in government aid, if used t purchase an American-built car. The auto industry (Ford, GM, Chrysler) sold 6.9 million cars and trucks in 2007.Reference:(http://online.wsj.com/mdc/public/page/2_3022-autosales.html#autosalesE). Does it not make more sense to give this money to the taxpayer, and will not this inject a "stimulus" into the economy? What am I missing here?
Let them file for bankruptcy and start over. Look around you-do you know anyone who drives an American car. Let them eat cake. The unions are responsible for their mess.
I think it's an idea worth considering. But I wonder if you can find 1,000,000 gold plated customers that the banks will loan to. 1 million cars would be 25% of annual production but would it be incremental or not? If not, you could still be looking at some sort of stimulus by the end of the year. I think that you've got to get home values under control first. The deflationary spiral started there and stabilizing those values will go a long way in fixing consumer balance sheets. A real estate mogul suggested the gov funding reduction of all mortgages to current market would go long way in restoring consumer balance sheets.
The only solution for Detroit is to test our next version of nuke on Detroit. That will take care of the problem.
I can't believe everyone misses the point. If we would tax all the imports even those foreign cars made here, we would find our cars much cheaper than the foreign competetion and Americans would buy and support the US car manufacturers. You don't see many US cars in Japan and the far east - I can't believe our politicians are so stupid!
Sirbruce, you are naive. If we won't buy our American cars, what makes you think Japanese will buy them. Actually, Ford tried and finally gave up.
Get the government out of business and commerce. Congressional bungling is the cause of all of our woes. Repeal the income tax and take away the cookie jar and watch the economy fly. A flat consumption tax would be fairer and reduce Congress interference with our lives and liberty!
What a disgrace it is that Nancy Pelosi would even consider using TARP to bail out our mismanaged auto companies and their overpaid unions. The US auto industry has been uncompetitive for decades because they can't manage union labor. Now the taxpayers are asked to pay the unions now that they have nearly bankrupted the companies that they work for. The executives of these companies need to figure out how to fix these comapanies - not at the expense of taxpayers.
All you guys missed talking about Trade-in Value.
American cars lose half of its value after one year.
We love Al Gore. There must be a job for him with the new administration.
unfortunately, if the gov't doesn't help, the ripple effect will be mammoth in size.
people who don't think the failure of Detroit's 3 is a big deal to the overall economy are way off.
1 in 10 jobs in the u.s. are tied to the auto industry.
If you want 3 million people out of a job immediately, and millions more in fallout, then by all means, let's not help them out.
I do not buy American cars. I have no vested interest other than trying to make people understand that the Dems ARE trying to help.
Republicans are sulking over a terrible presidential race for their party and an idiot that is still in office for another 73 days.
There should be NO government bailout money to any company or bank that pays compensation to any employee of more that $250,000!
Let Al Gore become Presient of the new GM Chrysler and show how he can make these companies a global, competitive leader in fuel efficiency and energy-efficient technologies that protect our environment, safeguard the taxpayers, protect auto workers and retirees, stop the erosion of our manufacturing base, and provide millions of new green jobs in the USA. Come on, Al, practice what you preach. Lead the way!
Oh, and Al, your compensation will be less than $250,000 a year.
Any proposed bailout will only help the UAW and be of temporary real help to the big three US auto makers. See
This study nearly two years shows US autos bore $2900 per car more in labor and healthcare costs than the Japanesse auto makers. Until this issue is resolved there is no real hope for a competitive automobile most especially as the cars are downsized.
We should not help the auto industry at all. The ones that destroy our public transport together with the oil companies. They are not viable. The money they are going to get could not guarantee their survival. So many years has passs.. the short sightedness of the industry leaders is to be blamed. The taxpayers should keep their money and not suck into this debacle. Our House and Senate is totally useless and just taking care of their own interest. Could the House and Senate guarantee the survival of GM????? NOPE. The probability of GM going bankrupt even with the help is 70-80%. It is definite a very poor investment.
When GM goes down retrain all the workers to build railways and public transport. The current infrastructure needs it. It is more wise to pay them this wages with the bailout to rebuilt our infrastructure than to pay money into the CEO pockets. With billions we could easily build a bullet train that runs across the country which is going to be more productive, lucrative than bailing this out moded, poorly manage company.
Look what the union did to the steel ind. If employs saved the money they pay in union dues they could invest in a good retirement. Unions screw up good companys.
tom 11:37pm,
Your ideas are brilliant.
ray of hope,
You are right on the button.
Excellent thought.
Al Gore has many many supporters. we love him.
Toss 'em all into Chapter 11. They make an inferior product, have bloated workforce and how many unions extort money from them?
If they go Chapter 11, they can renegotiate with their lenders, banks, etc... BUST the unions and switch from a defined benefit to a defined contribution plan and they'll save BILLIONS in pension/health benefits.
While we're at it, do the same with the airlines.
1. this plan would re-inforce failure not success; how is this a good thing?
2. would we do the same for honda, toyota, bmw et al in the u.s.?
3. what other industries represent a compelling national interest where subverting economic darwinism (a borrowed phrase i wished i had thought of first) is good thing?
4. if reinforcing failing industries to support a work force is good, why did we enact free trade agreements to put american manufactures out of work in the first place? if we offer a rescue plan, what is rational way of knowing how much is enough, when to stop and when the payoff to the american citizen is completed?
Any bailout must also be accompanied by a substantial reduction downward in labor costs. If a company is too important to fail and must be protected by the taxpayers, then it has less risk. There is no justification for pay and benefits packages greater than those of companies operating in the real world of free markets. If anything less risk implies less reward.
"We must safeguard the interests of American taxpayers..."
That should be the only consideration. There is a surplus of manufacturing capacity, so the so-called "Big Three" aren't necessary to maintain the viability of the industry. There will still be the need for some dealers who realize that they will have a market to service and trade all of the existing vehicles.
There is not enough money in the world to bail out all of the entities who suffer untoward results from bad choices.
As we move rapidly toward European style socialism we'll hear ever more plantif calls for help from the labor unions. Helping them with taxpayer dollars is just one more way of redistributing the wealth. That is precisely what our new President wants to accomplish. In that regard, gifting the Big Three big bucks will be a nice way to get into the redistribution game with a running start. It won't fix the auto industry's problems but it will certainly please the radical left.
So if McCain had become President, do you think he would throw the auto industry to the wolves and risk become an instantaneous Herbert Hoover. And when he did the same thing that Obama will do, would you be calling it European style socialism? The truth is that our system has been a lot more socialistic than anybody care to admit. But so long as you had a party that railed against it while enabling it, conservatives seemed to be alright with it. But its amazing how so many Republicans are willing to commit economic hari kari possibly to create a scenario so toxic that they can take back power in 4 years. Is an Obama Presidency so repugnant that you would doom millions of Americans to a Great Depression kind of fate? Is that what it has come to for you?
To Duke (12:00 am)and B...S....!(11:53 pm). I believe the phrase is: Cherchez la femme, coined, I believe by Alexander Dumas (The Count of Monte Cristo, 1857).
Dear Secretary Paulson and Speaker Pelosi:
I am writing to you to request that you review the basics of a competitive marketplace, get your house in order by streamlining government, and that you focus on unburdening the American taxpayer.
Stop experimenting in socialism and you are not the politburo. You are an elected offical accountable to the American public (believe it or not)! Smaller government is the answer here; not taking more of American's hard earned dollars.
Here there is an interesting essay published in the WSJ
's Auto section :
-( "OCTOBER 25, 2008 Essay
How Detroit Drove Into a Ditch
The financial crisis has brought the U.S. auto industry to a breaking point, but the trouble began long ago. Paul Ingrassia on disastrous decisions, flawed leadership and what the Motor City needs to do to survive".)
Here is the link :
After reading this , I really don't know if it worth saving them just because they are an American industrial icons .
We all recognize democrats owe the unions a lot. That does not justify taxpayers subsidizing poor management that has made the wrong products on a grandiose scale and surrendering to union leaders driven to protect their turf.
You are right on button.
Very well said.
Reid must have orchestrated the letter as my six year old has more intelligence than Pelosi. At least he knows that natural gas is a natural resource of the earth.
Chrysler failed once before and the taxpayers bailed it out. Now GM wants money to support its cashflow and money to retool for fuel efficient cars. Just what have they been doing for the past 15 years? GM had a prototype electric car 5 yrs ago, then scrapped it in favor of gas guzzling SUVs. Now we are supposed to bail them out. Get real, nobody has offered a bailout plan for the businesses that have failed in our town.
Anything with Pelosi and Reid's name on it is bound to cause more and more disasters for the public. WE stopped buying American made cars because they have been gas guzzling pieces of junk that constantly break down. Why bail out this industry when they have learned NOTHING !!! More money will be wasted on their CEO's than on any real improvements !!
It seems illogical for the Democrats to bail out an industry they've been trying for years to kill with regulations. Why not let it die and ask consumers to use bicyles or wind-powered magic carpets instead? Obama said he would call for national sacrifice and this seems as good a time as any.
Private companies must adjust and adapt to changing market conditions and demands. If not, they cannot compete in the world marketplace. Mismanagement and failed decisions are the responsibility of the company and no one else. File bankruptcy, restructure and create new innovative products to compete. The federal govn't has no business in this. The taxpayer is the innocent victim. After the car companies, who's next in line?
I wish you all would address your comments to your Sentators and Congressmen and women instead of posting here. The Unions support the Democrats; Obama received the most money from lobbysts; Frank and Dodd and the members of their committees received "awards" from the Real Estate, Insurance, and Financial Institutions. 401Ks are soon to disappear; company sponsored pension plans are soon to disappear. Are you getting the picture people? Big Brother will soon address you on your TV. You wanted a change? You'll get one soon with the Senate and Congress to thank under the leadership of the most liberal president. Blame the Bush Administration all you want but you will be wrong; blame the Sentate and Congress men and women.
Yes I agree GM makes inferior autos but the downturn has affected ALL auto dealerships and manufacturing facilities, not just American. No one is selling cars now, not Lexus, not Toyota, not Honda... No one wants to take on more debt at this time, and therefore the entire auto industry is at stake. God help us if GM goes down, you don't want to see that number of unemployed begging on the streets.
We have bailed out the auto industry three times. No More. We the people must unite and swamp our U.S. Senators and Congressmen. Let them know we will not tolerate another Corporate Welfare check. The fuel efficient and new technology is out there. We have solar nano technology that can run our battery driven cars with an organic nano paint. The problem is that it was created in a University. We all know what happens. It is bought by Corporations and kept out of the market. Let the auto industry die so entrepeneurs can come forward. NO MORE CORPORATE WELFARE!
I agree with clancy49. Not every big industry should get a handout. I'm in the Defense industry. We've got the likes of Barney Frank proposing a 25% reduction in our budget. Will we be next in line, or are we considered a Republican constituency and therefore SOL?
The automakers are the backbone of the military industrial complex.
Therefore they must be protected from dissolution.
The question is how it should be done:
In a manner that protects National Defense.
God bless America and the civilization of American people--solid as a rock.
Someone needs to tell that Pelosi B---- to Shut her Mouth about the Poor Auto industry...it's Bull....
They hear theirs Government Money and the auto makers start whining they need Money....Is Nancy getting a Kick Back from the Auto Manufacture's ? ........GET REAL NANCY !! Their part of the problem making all the Gas Guzzlers that people no longer want to buy. The Auto. Manufactures need to deal with it themselves...they don't need the Help it's the Low and Middle Class CITIZENS that need the HELP!! NOT the Company's and Businesses that have been ROBBING us BLIND for years !!
.........P.S. The American Public are SICK and TIRED of Nancy Pelosi's SELF SERVING CAUSES...She need's to QUIT or Get FIRED...She's SENILE !!!
No strings attached bailout cannot happen. Force them to move towards more value adding sectors and away from a dying industry for the US. The automakers can't compete with the cheaper, more fuel efficient automakers in Asia. Therefore retool the factories to make train cars, allocate federal road building to laying rail tracks across the US. That way i) we keep the people employed; ii) the companies stay intact in a related transport industry; iii) the US becomes less oil dependent; iv) we get a cleaner environment; v) less traffic congestion.
All good yes?
Republicans should call their bluff. Say, "Yeah, we'll offer the bailout assistance on condition of reorganization, a new business plan, executive pay limits and UNION CONCESSIONS." That will get the Democrats back-peddling.
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Last Classic Who Story you watched
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September 11 2012, 11:30 PM
The Borgified Corpse
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Re: Last Classic Who Story you watched
DWF wrote:
Earthshock was the last one I saw, it's always been one of my favorites, the fifth Doctor's catch phrase came from this one, the Cybermen stuck halfway though the door was awesome and I LOVED Tegan's "Mouth on legs" line.
Wait, the 5th Doctor had a catchphrase?
I just finished parts 3 & 4 of "Spearhead from Space" last night. Liz Shaw is absolutely adorable!
(It was weird though. Throughout part 4, I kept feeling like I was watching part 5 of 6, not part 4 of 4. I kept waiting for the next cliffhanger and all I got was a resolution.)
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Access Rights: Public
Partner: UNT Libraries
Degree Discipline: Biochemistry
Collection: UNT Theses and Dissertations
Development of Enabling Technologies to Visualize the Plant Lipidome
Date: August 2013
Creator: Horn, Patrick J.
Description: Improvements in mass spectrometry (MS)-based strategies for characterizing the plant lipidome through quantitative and qualitative approaches such as shotgun lipidomics have substantially enhanced our understanding of the structural diversity and functional complexity of plant lipids. However, most of these approaches require chemical extractions that result in the loss of the original spatial context and cellular compartmentation for these compounds. To address this current limitation, several technologies were developed to visualize lipids in situ with detailed chemical information. A subcellular visualization approach, direct organelle MS, was developed for directly sampling and analyzing the triacylglycerol contents within purified lipid droplets (LDs) at the level of a single LD. Sampling of single LDs demonstrated seed lipid droplet-to-droplet variability in triacylglycerol (TAG) composition suggesting that there may be substantial variation in the intracellular packaging process for neutral lipids in plant tissues. A cellular and tissue visualization approach, MS imaging, was implemented and enhanced for visualizing the lipid distributions in oilseeds. In mature cotton seed embryos distributions of storage lipids (TAGs) and their phosphatidylcholine (PCs) precursors were distribution heterogeneous between the cotyledons and embryonic axis raising new questions about extent and regulation of oilseed heterogeneity. Extension of this methodology provides an avenue for understanding metabolism ...
Contributing Partner: UNT Libraries
Manipulating Sucrose Proton Symporters to Understand Phloem Loading
Date: August 2013
Creator: Dasgupta, Kasturi
Description: Phloem vascular tissues transport sugars synthesized by photosynthesis in mature leaves by a process called phloem loading in source tissues and unloading in sink tissues. Phloem loading in source leaves is catalyzed by Suc/H+ symporters (SUTs) which are energized by proton motive force. In Arabidopsis the principal and perhaps exclusive SUT catalyzing phloem loading is AtSUC2. In mutant plants harboring a T-DNA insertion in each of the functional SUT-family members, only Atsuc2 mutants demonstrate overtly debilitated phloem transport. Analysis of a mutant allele (Atsuc2-4) of AtSUC2 with a T-DNA insertion in the second intron showed severely stunted phenotype similar to previously analyzed Atsuc2 null alleles. However unlike previous alleles Atsuc2-4 produced viable seeds. Analysis of phloem specific promoters showed that promoter expression was regulated by Suc concentration. Unlike AtSUC2p, heterologous promoter CoYMVp was not repressed under high Suc conc. Further analysis was conducted using CoYMVp to test the capacity of diverse clades in SUT-gene family for transferring Suc in planta in Atsuc2 - / - mutant background. AtSUC1 and ZmSUT1 from maize complemented Atsuc2 mutant plants to the highest level compared to all other transporters. Over-expression of the above SUTs in phloem showed enhanced Suc loading and transport, but against ...
Contributing Partner: UNT Libraries
Proteomic Responses in the Gill of Zebrafish Following Exposure to Ibuprofen and Naproxen
Date: August 2012
Creator: Adhikari, Prem R.
Description: Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most abundant environmental pharmaceutical contaminants. In this study, a proteomic analysis was conducted to identify proteins differentially expressed in gill tissue of zebrafish (Danio rerio) after a 14-day exposure to the NSAIDs ibuprofen or naproxen. A total of 104 proteins with altered expression as indicated by 2-dimensional electrophoresis were analyzed by liquid chromatography with ion trap mass spectrometry (MS/MS). A total of 14 proteins fulfilled our requirements for identification which included consistency among replicate gels as well as successful MS/MS ion searches with the MASCOT database. The most prominent feature of the differential protein expression observed after NSAID exposure was an up-regulation of proteins belonging to the globin family which are involved in the transport of oxygen from gills and availability of heme molecules required for synthesis of cyclooxygenase. Differential expression was observed at exposure concentrations as low as 1-10 µg/L indicating that altered gene expression may occur in fish subjected to environmentally realistic levels of NSAID exposure.
Contributing Partner: UNT Libraries
The Relationship of Force on Myosin Subfragment 2 Region to the Coiled-Coiled Region of the Myosin Dimer
Date: December 2011
Creator: Hall, Nakiuda M.
Description: The stability of myosin subfragment 2 was analyzed using gravitational force spectroscopy. The region was found to destabilize under physiological force loads, indicating the possibility that subfragment 2 may uncoil to facilitate actin binding during muscle contraction. As a control, synthetic cofilaments were produced to discover if the observations in the single molecule assay were due to the lack of the stability provided by the thick filament. Statistically, there was no difference between the single molecule assay data and the synthetic cofilament assay data. Thus, the instability of the region is due to intrinsic properties within subfragment 2.
Contributing Partner: UNT Libraries
Functional Characterization of Plant Fatty Acid Amide Hydrolases
Date: December 2010
Creator: Kim, Sang-Chul
Description: Fatty acid amide hydrolase (FAAH) terminates the endocannabinoid signaling pathway that regulates numerous neurobehavioral processes in animals by hydrolyzing a class of lipid mediators, N-acylethanolamines (NAEs). Recent identification of an Arabidopsis FAAH homologue (AtFAAH) and several studies, especially those using AtFAAH overexpressing and knock-out lines suggest that a FAAH-mediated pathway exists in plants for the metabolism of endogenous NAEs. Here, I provide evidence to support this concept by identifying candidate FAAH cDNA sequences in diverse plant species. NAE amidohydrolase assays confirmed that several of the proteins encoded by these cDNAs indeed catalyzed the hydrolysis of NAEs in vitro. Kinetic parameters, inhibition properties, and substrate specificities of the plant FAAH enzymes were very similar to those of mammalian FAAH. Five amino acid residues determined to be important for catalysis by rat FAAH were absolutely conserved within the plant FAAH sequences. Site-directed mutation of each of the five putative catalytic residues in AtFAAH abolished its hydrolytic activity when expressed in Escherichia coli. Contrary to overexpression of native AtFAAH in Arabidopsis that results in enhanced seedling growth, and in seedlings that were insensitive to exogenous NAE, overexpression of the inactive AtFAAH mutants showed no growth enhancement and no NAE tolerance. However, both active ...
Contributing Partner: UNT Libraries
Interactions of N-Acylethanolamine Metabolism and Abscisic Acid Signaling in Arabidopsis Thaliana Seedlings
Date: August 2010
Creator: Cotter, Matthew Q.
Description: N-Acylethanolamines (NAEs) are endogenous plant lipids hydrolyzed by fatty acid amide hydrolase (FAAH). When wildtype Arabidopsis thaliana seeds were germinated and grown in exogenous NAE 12:0 (35 µM and above), growth was severely reduced in a concentration dependent manner. Wildtype A. thaliana seeds sown on exogenous abscisic acid (ABA) exhibited similar growth reduction to that seen with NAE treatment. AtFAAH knockouts grew and developed similarly to WT, but AtFAAH overexpressor lines show markedly enhanced sensitivity to ABA. When low levels of NAE and ABA, which have very little effect on growth alone, were combined, there was a dramatic reduction in seedling growth in all three genotypes, indicating a synergistic interaction between ABA and NAE. Notably, this synergistic arrest of seedling growth was partially reversed in the ABA insensitive (abi) mutant abi3-1, indicating that a functional ABA signaling pathway is required for the full synergistic effect. This synergistic growth arrest results in an increased accumulation of NAEs, but no concomitant increase in ABA levels. The combined NAE and ABA treatment induced a dose-dependent increase in ABI3 transcript levels, which was inversely related to growth. The ABA responsive genes AtHVA22B and RD29B also had increased expression in both NAE and ABA treatment. ...
Contributing Partner: UNT Libraries
Metabolic Engineering of Raffinose-Family Oligosaccharides in the Phloem Reveals Alterations in Patterns of Carbon Partitioning and Enhances Resistance to Green Peach Aphid
Date: August 2010
Creator: Cao, Te
Description: Phloem transport is along hydrostatic pressure gradients generated by differences in solute concentration between source and sink tissues. Numerous species accumulate raffinose-family oligosaccharides (RFOs) in the phloem of mature leaves to accentuate the pressure gradient between source and sinks. In this study, metabolic engineering was used to generate RFOs at the inception of the translocation stream of Arabidopsis thaliana, which transports predominantly sucrose. To do this, three genes, GALACTINOL SYNTHASE, RAFFINOSE SYNTHASE and STACHYOSE SYNTHASE, were expressed from promoters specific to the companion cells of minor veins. Two transgenic lines homozygous for all three genes (GRS63 and GRS47) were selected for further analysis. Sugars were extracted and quantified by high performance anion exchange chromatography with pulsed amperometric detection (HPAEC-PAD), and 21-day old plants of both lines had levels of galactinol, raffinose, and stachyose approaching 50% of total soluble sugar. All three exotic sugars were also identified in phloem exudates from excised leaves of transgenic plants whereas levels were negligible in exudates from wild type leaves. Differences in starch accumulation or degradation between wild type and GRS63 and GRS47 lines were not observed. Similarly, there were no differences in vegetative growth between wild type and engineered plants, but engineered plants flowered ...
Contributing Partner: UNT Libraries
Stretching the Flexible Myosin II Subfragment Using the Novel Gravitational Force Spectroscope, and the Uncoiling of S2
Date: May 2010
Creator: Dunn, James W.
Description: Familial Hypertrophic cardiomyopathy (HCM) causes ventricle walls to thicken and often leads to sudden death especially in adults. Mutations in the subfragment 2 (S2) of β-cardiac myosin are implicated in the genetic disorder. This S2 region is a coiled-coil rod region resulting from the dimeric form of myosin II. It has been proposed that an elastic quality allows normal S2 to absorb force during the powerstroke according to the sliding filament model. To test the flexibility of single molecules of S2 against levels of physiological force, the Gravitational Force Spectrometer (GFS) is being developed. This novel system employs a standard microscope on an equatorial mount that allows the spectrometer to be rotated freely in space. Stationary glass beads are attached to a microscope slide where the molecule is tethered between the stationary bead and a smaller mobile bead. The GFS is oriented so that the force of gravity can act on the mobile bead and so impart a small force to the tethered subfragment. Additionally, a video system in conjunction with ImageJ software makes a distance measurement of the molecule possible with a resolution of around 11 nm. The S2 can be stretched parallel or perpendicular to the coiled coil ...
Contributing Partner: UNT Libraries
NSAID effect on prostanoids in fishes: Prostaglandin E2 levels in bluntnose minnows (Pimephales notatus) exposed to ibuprofen.
Date: August 2009
Creator: Bhandari, Khageshor
Description: Prostanoids are oxygenated derivatives of arachidonic acid with a wide range of physiological effects in vertebrates including modulation of inflammation and innate immune responses. Nonsteroidal anti-inflammatory drugs (NSAIDs) act through inhibition of cyclooxygenase (COX) conversion of arachidonic acid to prostanoids. In order to better understand the potential of environmental NSAIDS for interruption of normal levels COX products in fishes, we developed an LC/MS/MS-based approach for tissue analysis of 7 prostanoids. Initial studies examining muscle, gut and gill demonstrated that prostaglandin E2 (PGE2) was the most abundant of the measured prostanoids in all tissues and that gill tissue had the highest and most consistent concentrations of PGE2. After short-term 48-h laboratory exposures to concentrations of 5, 25, 50 and 100 ppb ibuprofen, 50.0ppb and 100.0 ppb exposure concentrations resulted in significant reduction of gill tissue PGE2 concentration by approximately 30% and 80% respectively. The lower exposures did not result in significant reductions when compared to unexposed controls. Measured tissue concentrations of ibuprofen indicated that this NSAID had little potential for bioaccumulation (BCF 1.3) and the IC50 of ibuprofen for inhibition of PGE2 production in gill tissue was calculated to be 0.4 µM. Short-term laboratory exposure to ibuprofen did not result in ...
Contributing Partner: UNT Libraries
Identifying genetic interactions of the spindle checkpoint in Caenorhabditis elegans.
Date: May 2009
Creator: Stewart, Neil
Description: Faithful segregation of chromosomes is ensured by the spindle checkpoint. If a kinetochore does not correctly attach to a microtubule the spindle checkpoint stops cell cycle progression until all chromosomes are attached to microtubules or tension is experienced while pulling the chromosomes. The C. elegans gene, san-1, is required for spindle checkpoint function and anoxia survival. To further understand the role of san-1 in the spindle checkpoint, an RNAi screen was conducted to identify genetic interactions with san-1. The kinetochore gene hcp-1 identified in this screen, was known to have a genetic interaction with hcp-2. Interestingly, san-1(ok1580);hcp-2(ok1757) had embryonic and larval lethal phenotypes, but the phenotypes observed are less severe compared to the phenotypes of san-1(ok1580);hcp-1(RNAi) animals. Both san-1(ok1580);hcp-1(RNAi) and san-1(ok1580);hcp-2(RNAi) produce eggs that may hatch; but san-1(ok1580):hcp-1(RNAi) larvae do not survive to adulthood due to defects caused by aberrant chromosome segregations during development. Y54G9A.6 encodes the C. elegans homolog of bub-3, and has spindle checkpoint function. In C.elegans, bub-3 has genetic interactions with san-1 and mdf-2. An RNAi screen for genetic interactions with bub-3 identified that F31F6.3 may potentially have a genetic interaction with bub-3. This work provided genetic evidence that hcp-1, hcp-2 and F31F6.2 interact with spindle checkpoint ...
Contributing Partner: UNT Libraries


text:
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text:
Figure 1 .
Dependence of growth on glucose upon the presence of citrate for the ancestors and evolved strains. The ratio and error for growth parameters was calculated by fitting a log-linear model with the strain:media interaction terms and block as the dependent variables. Unlike the ancestors (first two values), strains from three of the evolved populations were strongly stimulated by citrate in terms of both (A) growth rate and (B) yield. The remaining nine Cit- lineages, like their ancestors, exhibited little to no dependence upon citrate. We tested both 'large' (A-2A) and 'small' (A-2C) clones from the A-2 population, as it is known to have a stable, long-term polymorphism. Values represent the mean and 95% confidence intervals for the ratio of growth on glucose with citrate to growth without citrate for a given strain.
Leiby et al. BMC Evolutionary Biology 2012 12:151 doi:10.1186/1471-2148-12-151


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Vermont motel robbed of cashApril 22,2013DERBY Police are investigating an armed robbery of a motel in the northern Vermont town of Derby.
Vermont State Police said two men entered the Four Seasons Motel on Route 5 shortly after 9:30 p.m. Saturday and ordered the clerk to direct them to the motels money drawers and safe. One of the suspects pointed a gun at the clerk.
Authorities said the clerk complied with the demands, and the men left with an undisclosed amount of cash. Nobody was hurt.
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