text:
|Publication number
|Publication type
|Application number
|PCT number
|Publication date
|16 Aug 2005
|Filing date
|11 Mar 2002
|Priority date
|9 Mar 2001
|Fee status
|Also published as
|Publication number
|Thomas Laurell, Mats Allers, Henrik Jönsson, Hans W. Persson, Andreas Nilsson, Filip Tobias Petersson
|Original Assignee
|Erysave Ab
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (10), Non-Patent Citations (1), Referenced by (58), Classifications (17), Legal Events (3)
|External Links: USPTO, USPTO Assignment, Espacenet
The present invention relates to a device and a method for separating a fluid containing suspended particles into fractions of higher and lower concentration of said suspended particles using ultrasonic standing waves and micro-technology.
It is known that when particles in a fluid are subjected to an acoustic standing wave field, the particles are displaced to locations at, or in relation to the standing wave nodes. A number of attempts to use ultrasound standing wave field for the manipulation or separation are known.
In WO 00/04978 is described a device for performing the manipulation of particles suspended in a fluid. It comprises a duct for the flow of a fluid in which particles are suspended, and an acoustic transducer and a reflector for establishing an acoustic standing wave field across the width of said duct, the spacing between the transducer and reflector being 300 μm or less.
In an abstract to the 4th annual European conference on micro & nanoscale technologies for the biosciences (NanoTech 2000), Hawkes and Coakley describes a "force field particle filter, combining laminar flow and ultrasound standing waves" with an acoustic path length at right angles to the flow of 0.25 mm.
In WO 98/50133 is described a device for performing the manipulation of particles suspended in a fluid. It comprises a duct for the flow of a fluid, in which particles are suspended, said duct having means for establishing an acoustic standing wave field so that the particles are displaced to form parallel bands. The duct includes an expansion in width.
In IBM, technical disclosure bulletin vol. 25, No. 1, June 1982, page 192/193 is disclosed an ultrasonic continuous flow plasmapheresis separator comprising two orthogonally mounted ultrasound transducers with one reflector each and a volume between where a dilute suspension is subjected to an acoustic standing wave field.
In JP 06241977 A is described a fine particle measuring instrument that uses a standing ultrasonic wave with a node at the centre of a flow cell to centre and concentrate fine particles.
In EP 0 773 055 A2 and A3 is described a method and an apparatus for handling particles by an acoustic radiation force. The apparatus comprises a chamber for accommodating a fluid containing the particles to be concentrated, filtered or arranged, and a plurality of ultrasound sources disposed to make direct or indirect contact with the fluid. The apparatus also comprises a control device for controlling said ultrasound sources to generate an ultrasound beam obtained by superimposing ultrasound beams from said ultrasound sources on one another, said beams each having a specific intensity, a specific frequency and a specific phase.
In WO 93/19367 A2 and A3 is described a method and an apparatus for particle aggregation, said apparatus comprising a tube for containing of a sample of a liquid, and an ultrasonic transducer arranged to generate a standing wave ultrasound field transverse to the tube. The standing wave exhibiting a progressive change in pressure amplitude transverse to the tube, so that, in use of the apparatus, particles in suspension are displaced transversely of the tube to one or more predetermined regions. After termination of exposure to the standing wave particles are allowed to settle and can then be inspected. Appreciated use of the apparatus includes carrying out immuno-agglutination assays. The document is based on U.S. Pat. Nos. 5,665,605 and 5,912,182.
In JP 07 047259 A is described an apparatus for transporting fine particles in fluid with ultrasonic waves. The apparatus comprises a multitude of ultrasonic wave generating elements two-dimensionally arranged on two flat plates. Between the plates a solution can be deposited.
The present invention provides a device and a method for separating particles from fluids using ultrasound, laminar flow, and stationary wave effects comprising micro-technology channels formed in the surface portion of a plate, having integrated branching points or branching forks, and an ultrasound source arranged in close contact to an opposing surface of said plate.
Standing waves are generated in the channels so that particles suspended in the fluid are brought into certain lamina of said fluid, and that one or more lamina are formed devoid of particles, or are formed carrying particles of different properties than the first mentioned ones. Said laminae are thus arranged perpendicular to said plate, this is important because the branching of a channel must take place within the plate, so that a connection with another channel can take place also within the same plate. The advantages of this will be obvious below.
One of the characteristics of the invention is that the ultrasound source is arranged in perpendicular contact with the plate, conveying ultrasound energy in a direction that is perpendicular the plate. The inventors have tested and proved that in the present invention, as a result of the dimensions of the channels and the properties of the plate and the ultrasound transmitter, a standing wave is generated that reaches from one side wall of a channel to the opposing side wall of the same channel. It would normally be expected that such an arrangement would generate (only) a standing wave reaching from a bottom wall to a top wall of said channel, continuing in a direction of the original energy flow.
The inventors have also realised the great importance of this idea. Because, according to the invention, the ultrasound source now do not have to be a part of the plane or layer where the channels reside, and space becomes available for packing more channels into a limited space, greatly enhancing the possibilities of manufacturing devices with a multitude of parallel channels providing high capacity particle separation. A high degree of particle separation could also easily be provided by a serial arrangement of separation units, as will be further explained below. The capability of high yield parallel and serial processing of a fluid using ultrasound is thus a central part and consequence of the inventive concept.
The above is possible because the channels and branching points are formed in a plate comprising one piece of material or in a few pieces of material closely bonded together. No special reflectors or the like are used. It may also be possible to use more than one ultrasound source. Thin dividers are arranged to separate the laminar flows after the branching points, thereby enhancing the effectiveness of the device. The device is preferably manufactured using silicon technology benefiting from the possibility of small precise dimensions, and the ultrasound energy could preferably be delivered by a piezoelectric element, which in turn could be driven from a control unit capable of delivering electrical energy of certain shape, frequency and power.
The invention is defined in the accompanying claim 1, while preferred embodiments are set forth in the dependent claims.
The invention will be described below with reference to the accompanying drawings, in which:
Referring to
At the back of the plate 51, means for delivering ultrasound energy to the plate is arranged in the form of a piezoelectric element 150, 853. The device will function as follows:
A fluid with suspended particles entering the base stem 110 at the inlet 160 will flow towards the branching point 175 because of an arranged pressure gradient, which gradient could be created by e.g. a suction pump, a pressure pump, a syringe or by gravity. By controlling the frequency of the ultrasound and use of certain frequencies suitable to the dimensions of the base stem 110, particularly the width 185 of said stem 110, a stationary wave pattern is formed in the fluid inside said stem 110. Especially there will form a stationary wave pattern orthogonal to the direction of the flow between a left 810 and a right 820 side wall of the base stem 110. Pressure nodes will form in greater numbers in the middle part of the channel than at the walls, where pressure antinodes will form. During said flow, particles in the fluid will tend to accumulate in nodes of said stationary wave-pattern, or in certain layers in relation to the nodes depending on the particles' density/densities/acoustic impedance relative to the surrounding fluid. Particles with a higher density than said surrounding fluid will tend to accumulate in the nodes, whereas particles with a density lower than the surrounding fluid will tend to accumulate in the antinodes. The layers of fluid discussed in the following are the layers parallel to the sidewalls 810, 820 of the base stem 110.
Depending on the density/acoustic impedance, size and weight of the particles, certain patterns of accumulations of particles will be formed. This is an advantage when separating out particles of a certain weight and/or size from a medium containing a spectrum of particles of different density/acoustic impedance. Generally, particles having a density higher than the density of the surrounding fluid, accumulates in the nodes, and particles having a density lower than the fluid without particles, accumulate in the antinodes. By providing a branching fork with two side branches or arms and one central branch or arm 140 as shown in
Depending on the resonance conditions, confer
By controling the frequency of the uitrasound that creates the standing wave field it is possible to generate a standing wave between the side walls of the base stem 110 with a standing wave length 0.5, 1.5, 2.5 etc. wavelengths, i.e., n times 0.5 wavelengths, n-1, 3. 5, 7 . . . cf.
Preferred embodiments of the invention therefore include means for controlling the frequency of the ultrasound generating means. In
Other embodiments of the invention include bifurcation and "trifurcation" of different shape, integrated on the same piece of material, and with the overall purpose to divide the laminar flow of fluid.
Parallel arrangements of single or serial structures according to
Returning now to
Preferred embodiments include embodiments with channel systems integrated with a single substrate or deposited on a substrate by a continuous series of compatible processes.
The device according to the present invention can be manufactured for example in silicon. The requirement to make the walls of the base stem (810, 820) essentially perpendicular to the plate and parallel or near parallel to each other is easily fulfilled by using silicon of a <110> crystal structure and well known etching techniques. The desired channel wall structure described may also be realised by deep reactive ion etching, DRIE.
It is also possible to form the layers in plastic materials, for instance by using a silicon matrix. Many plastics have good chemical properties. The silicon layer structure can be produced by means of well-known technologies. Channels and cavities can be produced by means of anisotropic etching or plasma etching techniques. The silicon layer may be protected against etching by an oxide layer that is by forming a SiO2 layer. Patterns may be arranged in the SiO2 layer by means of lithographic technologies. Also, etching may be selectively stopped by doping the silicon and using p.n. etch stop or other etch stop techniques. Since all these process steps are well known in the art they are not described in detail here.
The above described technology is also suitable for producing a matrix or mould for moulding or casting devices of the invention in e.g. plastic.
The piezoelectric element providing the mechanical oscillations is preferably of the so-called multi-layer type, but a bimorph piezoceramic element may also be used as well as any other kind of ultrasound generating element with suitable dimensions.
An appreciated application of an embodiment of the invention is in the field of cleaning a patient's blood during surgical operations. The object in this field is to sort out the red blood cells from the contaminated plasma. Contamination could include air bubbles, fat particles, coagulation products and other not desirable biological material. The red cells will thereafter be brought back to the patient's circulation. One disadvantage with prior art in the form of centrifuges is that the red blood cells can become deformed, a disadvantage that is not present with a device according to the present invention.
Depending on the application, the shape and dimensions of the channel, the length of the stem 110 and the arms 120, 130, 140, and the frequency of the ultrasound may vary. In an application for separating out red blood cells from diluted blood recovered from a patient during a surgical operation, the channel is preferably rectangular in cross-section and the stem part of the channel has a width of 700 μm for a one-node standing wave ultrasound field. Greater widths will be appropriate for standing wave ultrasound fields with more nodes.
The mechanical tolerance of the width of the channel is important. The difference should preferably be less than a few percent of half the wavelength of the frequency used in the material/the fluid concerned.
A first outlet tube 1631 is providing a connection from the nine intermediate outlets 1531-1539 via a first collecting manifold to a free end 1641 of said first outlet tube 1631. A second outlet tube 1632 is providing a connection from the eight central outlets 1541-1548 via a second collecting manifold to a free end 1642 of said second outlet tube 1632.
When fluid flows in the direction of the arrow 1804, ultrasound-standing waves are separating the particles in the channel unit into three fluid layers 1801-1803. The position of the ultrasound source is indicated by the rectangle 1810.
The described process separating two types of particles is illustrating a solution to the need within the field of medical technology to separate blood components from each other, i.e. red and white blood cells and platelets (erythrocytes, leukocytes and thrombocytes), also called the formed elements of the blood.
Known art in the field comprises mainly or solely solutions based on centrifugation. A disadvantage is that it is very difficult to obtain a complete separation of the formed elements, instead a so-called "buffy coat" is obtained. This buffy coat comprises a high concentration of thrombocytes, leukocytes and a low concentration of erythrocytes. In this context one should bear in mind that the sensitive thrombocytes have been centrifugated and subjected to high g-forces, which probably have induced an impaired function within said erythrocytes.
An embodiment of the present invention can be used to separate thrombocytes and leukocytes from erythrocytes, because they possess different densities as can be seen in table 1. Blood consists of plasma and formed elements.
Relative density
Standard deviation
Glucose 30%
Glucose 50%
Addex electrolyte
Relative density. Source: Geigy Scientific Tables
Other solutions possible, iodine control agents.
As can be seen in table 1, different components have different density. The variation in density is very small for the table entries. When ordinary blood is separated, a channel unit will separate all formed elements in the same way, because their density is higher than the medium they are suspended in, i.e. the plasma.
As an alternative embodiment, the medium is modified, i.e. the plasma is modified so that its density is altered, giving the possibility to separate the different blood cells. This is achieved by adding an amount of denser liquid to the plasma and thereby dilute the plasma to a lower concentration, but with a higher density.
Take 100 ml blood with a haematocrit of 40%. This entails that 60% (=60 ml) of the blood is plasma. The plasma has a density of 1.0269. By adding 30 ml of 50% glucose solution we get according to the formula:
v1 is the volume of the first fluid
d1 is the density of the first fluid
v2 is the volume of the second fluid
d2 is the density of the second fluid
dtot is the density of the mix
The density of the mix medium becomes 1.0746.
When this mixture is entered in an embodiment, a separation is achieved where thrombocytes and erythrocytes are directed into separate branches, because now the thrombocytes are lighter than the medium.
This is of course just an example. It is also possible to separate out leukocytes because they have a specific weight, different from the one of erythrocytes and thrombocytes. It should also be possible to separate out bacteria and virus with this method. The method can be used on all solutions except those solutions where it is impossible or otherwise inappropriate to manipulate the density of the solution. It is also possible to separate out bacteria and stem cells from cultures of the same, having them suspended in a suitable solution.
FIG. 19 and
It will be appreciated by persons skilled in the art that the structure of the device according to the present invention has several advantages including ease of manufacture and solving of the problem of separating particles liable to disintegration in filtering and centrifugation processes.
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|U.S. Classification
|210/708, 209/155, 422/128, 204/158.2, 210/95, 210/748.05
|International Classification
|Cooperative Classification
|European Classification
|20 Oct 2003
Owner name: ERYSAVE AB, SWEDEN
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:LAURELL, THOMAS;ALLERS, MATS;JONSSON, HENRIK;AND OTHERS;REEL/FRAME:014751/0747;SIGNING DATES FROM 20030903 TO 20030908
|31 Jan 2009
|Fee payment
Year of fee payment: 4
|13 Feb 2013
|Fee payment
Year of fee payment: 8


text:
Our online process saves time and allows you to pre-register at your convenience.
Our concierge can help reduce demands and stresses during your hospital stay.
For your convenience you can pay your hospital bills online and manage your account.
Take a virtual tour and experience CRH in an exciting new way.
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Many people believe that Alzheimer disease can't be treated. The truth is that drugs are available that may help slow the progression of symptoms. These drugs don't work for everyone. But, they do offer some hope for the more than 5 million people who have Alzheimer disease.
The FDA has approved 5 drugs to treat Alzheimer disease. All the drugs may help temporarily stop some of the disease's symptoms from getting worse. These include confusion and forgetfulness.
In addition to memory loss and confusion, Alzheimer disease can make speech and mood swings worse. In the later stages, the disease destroys a person's personality and ability to think and function. In some people, Alzheimer disease worsens quickly. In others, it proceeds slowly.
Just as the course of Alzheimer disease isn't clear, neither is treatment. Existing drugs may slow the progression of Alzheimer disease in some people. The drugs are most useful when a person starts taking them as early as possible. It takes 2 to 6 weeks before any results appear.
These 3 drugs are used to treat the disease in its early to middle stages:
Galantamine (Razadyne)
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A drug that can be used for all stages is called Donepezil (Aricept). Another drug, memantine (Namenda), is the only drug approved by the FDA for the later, more severe stages of Alzheimer disease. .
Certain side effects may put off people from using drugs for Alzheimer disease. For example, tacrine may cause liver damage. Donepezil, galantamine, and rivastigmine can cause diarrhea, nausea, and vomiting. Memantine may cause dizziness and headache.
Using these drugs properly may improve quality of life. It will also help the person's caregivers as well. Ask your healthcare provider for more information.

subset: commoncrawl


text:
1996 Mercury Marquis
I have a 1996 Mercury Grand Marque LS, w/ auto climate controle. When I change the temperature there used to be a loud clicking sound from inside the dash board. Now it always blowes hot air no matter what the temperature is set to, even with the A/C on. Could this be the controle unit, or is there a faulty vacuum valvle?
John 223
March 24, 2007.
March 24, 2007.
It's the srvo that attaches to the blend door, either the door or servo needs attention.
Jun 15, 2007.
Jun 15, 2007.
I have a 1994 D21 PU, with 2.4, A/T. My problem began when I went to start the truck. Turned the key and had nothing -just the clicking of the relays, etc. Thought it was the battery ...
4 answers • 1994 Nissan Truck • 135,000 miles
I have a 97 Ford F150. went out to start my truck but got a sudden clicking noise but the truck wont start. We checked the cam sensor and the crack sensor. Still no luck so we checked ...
8 answers • 1997 Ford F-150 • 169,000 miles
My name is ray i have a 1993 infiniti g20 it has 76,550 miles on it just replace starter has new altenator oil changed regulary no check engine lights on its a great car.but for some ...
1 answer • 1993 Infiniti G20 • 76,550 miles
My car is making a clicking noise when I am at a stop, my car is in park, or my foot is off the gas. Sometimes it is quieter then others but it is a pretty fast like click click click. ...
1 answer • 2003 Hyundai Elantra


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text:
cherry clafoutis
You know what? I'm having a fantastic summer. Life is incredibly sweet, juicy opportunities for personal and professional development are cropping up left and right, we're going to Napa in one month and — I'm thrilled.
You know what? I'm having a fantastic summer. Life is incredibly sweet, juicy opportunities for personal and professional development are cropping up left and right, we're going to Napa in one month and — I'm thrilled.
On Friday, someone asked me if there was a food I was eager to try. I answered that I'd never baked or even tried a single madeleine in my whole life. Four hours later, I had done both, so emboldened by the suspicious ease of marking items off my wish-list, I next mentioned that I had yet to get that puppy I've been asking for. No dice on that one yet.
Despite it being an amateurish cliché, blaming your mother and all, I have to insist because it's completely her fault that that anything less than Julia Child's coq au vin with brown-braised baby onions and sautéed mushrooms on Tuesday night would be inedible, cruel beyond comparison. You see, she is the one who after reading the post about my unending obsession with Paris and French food, bought me My Life in France, which is akin to putting a loaded, I don't know — egg beater? in my infatuated hands. I am but 75 pages into the book and I'm ready (and not for the first time) to book my one-way ticket. If nothing else, I plan to hold my breath or at least cut off bacon-and-meat kitchen dallies until my husband sends me to the Cordon Bleu.
Living in a 660 square foot apartment makes in impossible for us to host Thanksgiving dinner, which is too bad because you just know I've got that meal all planned out in my head, from the cornbread-chorizo stuffing to the turkey recipe and root vegetable gratin, ready and waiting for the day we get a dining room table! (Also, a dining room. Details.) We also can't host the major Jewish holidays or but when we asked for the less-popular or significant Hanukah, we were deemed acceptable hosts so long as we don't poison anyone, so for the second year now, we've run with it.
We could speak about the meaning of life vis-a-vis non-consequential/deontological theories, apodictic transformation schemata, the incoherence of exemplification, metaphysical realism, Cartesian interactive dualism, revised non-reactive dualism, postmodernist grammatology and dicey dichotomies. But we would still be left with Nietzsche's preposterous mustache, which instills great anguish and skepticism in the brain, which leads (as it did in his case) to utter madness. I suggest we go to Paris instead. — The Principles of Uncertainty
In the two years since I've rejoined the meat-eating world after a 15-year absence, I've re-immersed in, I'd like to think, a considerable range of flesh. There's been more chicken than you can shake a drumstick at (sorry, couldn't resist), turkey, pork, beef and even some new things at tablecloth-ed restaurants like duck and quail. But, I've sorely lacked in my embracing of les fruit de la mer and this constantly mocks me on my journey to become the kind of eater that embraces everything edible. (I heard Ruth Reichl say a few weeks ago that the only food she simply will not eat is honey. Just one thing! And it's honey!)


text:
A New Agenda (1980-1990). (Celebrating the Past: A Century of Challenge, Part 8)
Part VIII: A New Agenda (1980-1990)
This is the eighth of nine segments designed to commemorate the NAGWS Centennial, 1889-1999. This segment will focus on the accomplishments of ten past-presidents who served from 1980 to 1990. The 1980s saw a major setback to Title IX, when the Grove City College decision interpreted Title IX as applying only to the specific program or activity earmarked for federal assistance, and not to the institution or school as a whole (Mottinger, 1988). NAGWS actively lobbied for the passage of the Civil Rights Restoration Act. This act would reinterpret Title IX more broadly, as Congress had originally intended, prohibiting educational institutions from discriminating based on sex. In 1983, the NCAA co-opted the AIAW (which had been born from NAGWS in 1979) and began to oversee women's intercollegiate athletics. As the last AIAW presidents, the following individuals placed their mark on the shaping of women's intercollegiate athletics: Christine Grant (1980-1981), Donna Lopiano (1981-1982), Merrily Baker (1982-1983), and Virginia Hunt (1983 elect). With the NCAA takeover of intercollegiate sport for women, challenges continued for the control of the rules for girls' and women's sport. By the end of the 1980s, NAGWS stopped publishing the rules for women's basketball. The National Federation published the high school rules, while the NCAA published the collegiate rules (Hult, 1991). In 1983, NAGWS, the United States Olympic Committee (USOC), and the Women's Sports Foundation sponsored a major conference, "The New Agenda: A Blueprint for the Future of Women's Sports," which led to the creation of National Girls and Women in Sports Day. NAGWS continued its strong bond with the USOC and the National Governing Bodies. By the end of the decade, NAGWS was redefining its role in equity for girls and women in sport. With a steady decrease in the number of women in leadership positions in sport, NAGWS was ready to focus on increasing female leadership in the athletic arena. - Shawn Ladda, Manhattan College, Feature Editor.
Doris Corbett
Biography: Howard University
Accomplishments: Corbett facilitated international congresses, workshops, and clinics in Latin America and the Caribbean. These events focused on institutional curriculum development, sport specific clinics, and issues related specifically to women in sport. She also appointed the first minority representative to the NAGWS Executive Board (Corbett, personal communication, July 28, 1999).
Helen "Susie" Knierim
Biography: Slippery Rock University
Accomplishments: Met with the NCAA to negotiate the continuation of publication of the women's basketball rule books for at least one more year. Continued lobbying government to enforce Title IX, especially for schools with poor women's sports programs.
Bonnie Slatton
Biography: University of Iowa
Accomplishments: The first edition of the joint USA-Latin American/Caribbean Congress on Women and Sport was held at Temple University in May, 1982 ("Latin American Project," 1982, p. 1). The purpose of the Congress was to provide an opportunity for participants to exchange practical and scientific information that would be helpful in advancing women's sport in the Americas. The AIAW is co-opted by the NCAA, and NAGWS challenges the NCAA based on antitrust laws.
Jean Perry
Biography: University of Nevada-Reno
Accomplishments: "While we certainly have experienced a great increase in opportunities for girls and women to participate as athletes, the past ten years have shown an even more dramatic decrease in the number of women coaches, athletic administrators, and sports officials" (Perry, 1986, p. 33). Coaching institutes and leadership conferences were seen as a way to address this increasing problem. The New Agenda Conference was held November 3-6, 1983, in Washington, D. …


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I sit down in front of my computer or the TV, and I automatically want to munch! I realize it's because I'm watching something and being inactive, and I want to keep my hands busy, so I drag my nail box out, and start soaking, filing, shaping, and polishing. If you take your time, this could last an hour, and you'll have the best looking hands EVER. It's all about pampering, and spending time with yourself mindfully, and not stuffing your face mindlessly.
I give myself a manicure, or put on really gooey handcream...that way I'm taking care of myself instead of stuffing my face!334
Learning to forgive yourself instead of falling apart for slip-ups give you the chance to make a fresh start and learn from situation
Schedule a Spa manicure and pedicure once a month to relieve stress and enhance self-esteem! 224


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Dupont has donated a collection of patents and other intellectual property on using nanotechnology to generate electron beams to The University of California, Davis, College of Engineering.
The donation supports the Department of Electrical and Computer Engineering particularly Professor Charles E. Hunt's, Vacuum Microelectronics group. They use nanotechnology to build tiny structures that confine enormous electric fields in a very small volume of material. The material then emits electrons that can be focused into a beam. Known as "field-emission" devices, they have applications including high-efficiency lighting, biomedical devices, nanoscopic x-ray sources, cathode ray tubes and microwave devices.
Posted 2nd February 2004
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Money Raised by "Team Forge" in 2015: $10,214.20
"Team Forge" will again be participating in the Door County Half Marathon & 5K at Peninsula State Park on May 2, 2015 to raise money for the new Blacksmith Forge at The Clearing.
Our fundraising goal this year is a whopping $6000. Yup, it's a lofty goal, but with your help "Team Forge" will give The Clearing's Forge project a big boost. Please help us meet our goal by making an online donation or pledge today!
Thanks again for your continued support everyone!
Erik (half) Sara (half) Heidi (5K) Melinda (5K) Tammy (5K) Mike (5K) Cindy (5K) Carolyn (5K) Siobhan (half) Mary Ann (5K) Anka (5K) Glenna (5K) Members "Team Forge"
p.s. It doesn't take a big donation either. Think about pledging $2 or $3 dollars per mile.(A half marathon is 13.1 miles.) 70% of last year's donations were $2 or $3 per mile. Every little bit helps!
p.p.s Interested in joining "Team Forge"? We'd love to have you running, walking or cheering by our side on May 2nd, 2015! Get on board by giving Erik a call at The Clearing.


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DAVIE — What a difference one season has made for Dallas Thomas' NFL career.
A year ago, it seemed the Miami Dolphins' 2013 third-round pick was headed for the bust pile. The team was submerged in a bullying scandal that cost the Dolphins two starting offensive linemen. Even though Miami was desperate for replacements, Thomas couldn't sniff the field.
The former Tennessee offensive guard struggled as a rookie in training camp when given the opportunity to prove he could replace John Jerry as the starting right guard. He got embarrassed numerous times in the exhibition season, and Miami moved him to right tackle.
Then when the Dolphins were searching for a left...


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Starship class
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To add new fields to this infobox or change the colors, follow the instructions on {{Infocell}}.
This is an infobox for technical and usage information on various classes of space vehicles. The fields are relevant to starships, fighters, shuttles, and most other spacefaring constructs. For individual examples of a known class, do not use this template. Use {{Individual ship}} instead.
For space stations, we are now using {{Space_station}}.
When adding fields to this box, be sure to update Template:Starship_class/preload at the same time.
Cut and paste the following code into your article, then put the relevant specifications after the "=" signs.
{{Eras|}} {{Starship_class |imageBG= |image= |name= |manufacturer= |designer= |line= |model= |class= |cost= |modifier= |sysmods= |length= |width= |height= |mass= |max accel= |mglt= |max speed= |maneuverability= |engine= |hyperdrive= |hdrange= |hdsystem= |poweroutput= |power= |shield gen= |hull= |sensor= |target= |navigation= |avionics= |maincomp= |countermeasures= |armament= |complement= |bays= |escapepods= |crew= |skeleton= |passengers= |capacity= |cargohandling= |consumables= |lifesupport= |communications= |othersystems= |availability= |role= |firstuse= |retired= |era= |affiliation=}}
Data fields
- name – Simply list the name of the ship in italics.
- image – Put a link to the main image which represents the class. If the image is 250 pixels wide or larger, specify an image width of 250 pixels. If the image is smaller than 250 pixels wide, do not specify the size.
- imageBG – if the image is smaller than 250 pixels wide, listing the image's background color here will keep a large blue border from appearing around it.
- manufacturer – Put the manufacturer name here
- designer – Put the name of the person(s) or organization(s) that designed the craft, if different or more specific than manufacturer
- model – List the full official class name.
- class – List the primary classification of the model
- cost – List the cost of the ship (and the currency type if needed)
- length – Length of the ship
- width – Width of the ship
- height – Height of the ship
- max accel – Maximum acceleration in "g"
- mglt – Speed in MGLT -- do not use if "max accel" is known. MGLT is primarily a gameplay mechanic.
- max speed – Maximum atmospheric speed
- maneuverability – Maneuverability rating
- engine – Types of sublight and atmospheric drive systems
- hyperdrive – Hyperdrive ratings
- hdrange – Hyperdrive range (in light-years)
- hdsystem – Hyperdrive system (or "none" if no hyperdrive)
- poweroutput – Power output in watts (this field will rarely be used)
- power – Types of power systems
- shield gen – Type of shield generators (with rating if known)
- hull – Type of hull materials (with rating if known)
- sensor – Types of sensor systems
- target – Types of targeting systems
- navigation – Navigation computer systems
- avionics – Avionics/flight control systems
- countermeasures – ECM and stealth systems
- armament – List of weaponry equipped
- complement – Support craft carried aboard
- crew – Number of crew (with crew breakdown if known)
- skeleton – Minimum crew required for operation
- passengers – Number and type of passengers carried
- capacity – Cargo capacity (be careful, this may overlap with complement and passengers)
- consumables – Duration of consumable goods stored aboard
- othersystems – Any systems not listed above
- role – List what the ship is used for here
- firstuse – Enter the date the class was introduced
- era – List the eras in which the ship is used here
- affiliation – List the governments and major organizations that use the ship here


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BPL Community Profile
Lance Marshall (Lancem) - BPL Lifetime Member
You cannot send this user a personal message (PM) because they have not specified a PM email address yet.
All Forum Posts by Lance Marshall
Re: Canister
Use a canister where required. In the few areas that they are required, the existing food storage lockers aren't an allowed option. Last summer three different rangers checked my permit a...
Re: Where are the new Backpackinglight articles?
There is a link on the Home page to the list of past articles in reverse chronological order. The link is titled "ARTICLES: Archives" The water treatment articles are on the secon...
Re: A good start
Joe, your international UL travel experience is impressive! Here's my 2 cents, FWIW: To more accurately resemble a typical gear list, reclassify most of your clothing weight from 'worn&...
Re: Or not.
Nicely put David. I think that using your real name, even just your first name and initial adds accountability and integrity to posts. The forum terms of use say it best: "If you choose...
Re: Hanging Scale - up to 50 pound capacity, and within 1 oz precision
I use a Berkley FS50 fish scale which read in pounds and ounces up to 50 pounds. It has been pretty accurate when comparing total pack weight to the sum of my gear list. I just now weighed my g...
Re: what sort of water containers do you use with a steripen?
I use the Steripen Classic with Snapple or Gatorade bottles and a modified bottle cap. Works well. Gatorade cap with tapered hole. Together with SteriPEN, inverted. Inside of tapered...
Re: Bullets
You can also create a bulleted list directly by wrapping the text in HTML code. The <ul > tag opens an unordered list. The <li > tag opens a list item. The </li > tag closes...
Re: tyvek vs polycro as footprint/ground cloth for rocky Sierra camp site.
What is the weight and packability diffrences between 2m and .7m polycro? 34 x 80" polycryo (1-1/4 oz) vs. 34" x 80" 2 mil plastic (3 oz): Polycryo definately packs smaller....
Re: Great article looking forward to part 3
Thanks for the great article. One source that has helped me decide which water to treat, which method to use, and how long to wait is the EPA Guide Standard and Protocol for Testing Microbiolo...
Re: Thick-reseable Garbage Bags
aLOKSAK bags are quite thick. Available lots of places. For reference, here are some measurements: Aloksak about 6 mil thick (single layer): OPsak about 4 mil thick (single layer): ...
All Reader Reviews by Lance Marshall
Lance Marshall has posted no reviews.


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Spoiler Alert: The sentences/chapters are split towards the end of the book – I just want to reassure you that this is NOT a printing error; they are supposed to be like this as the affected sentences are part of 'dream sequences'.
The FINAL shocking, heart-wrenching book in the jaw-droppingly stupendous Skulduggery Pleasant series. Valkerie. Darquesse. Stephanie. The world ain't big enough for the three of them. The end will come...
The War of the Sanctuaries has been won, but it was not without its casualties. Following the loss of Valkyrie Cain, Skulduggery Pleasant must use any and all means to track down and stop Darquesse before she turns the world into a charred, lifeless cinder. And so he draws together a team of soldiers, monster hunters, killers, criminals...and Valkyrie's own murderous reflection. The war may be over, but the final battle is about to begin. And not everyone gets out of here alive...
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Comments about The Dying of the Light:
Been a massive Skulduggery Pleasant fan for years and the year wait for this book was torture. Little did I know that this book was its own sick form of torture that ruined the entire series for me. Not one good thing to say about this book other than absolute trash.
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Comments about The Dying of the Light:
the dying of the light is the best climax of a fantasy series i have ever read from trying to stop the evil sorceress Darquesse to skulddugery recovering from his loss its just a brilliant book
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Comments about The Dying of the Light:
Great finish to the series. Well written, exciting, this book will keep you reading to the wee hours of the morning until you hit the ending.
PRAISE FOR THE SKULDUGGERY PLEASANT SERIES: "This is a writer at the height of his powers and Landy is getting better with every book... Whatever your age, read them and enjoy the ride." Irish Independent "Fast and funny" The Times "A fast evolving plot and a great mix of scariness and humour" 5 star review, Sunday Express
Series: Skulduggery Pleasant
Audience: Children
For Ages: 9+ years old
Format: Paperback
Language: English
Number Of Pages: 608
Published: 1st September 2014
Publisher: HarperCollins Publishers
Country of Publication: GB
Dimensions (cm): 21.0 x 13.6 x 4.4
Weight (kg): 0.63


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March 10, 2014
Posted by Kristina Jenkins
Filed in:
Attractions News
Enter to win the Ultimate Rocky Weekend Sweepstakes and this could be you celebrating an epic weekend in the City of Brotherly Love. (Photo by S. Ruth for Visit Philadelphia)
Yo, it's Rocky! Fans of the Academy Award-winning 1976 film Rocky can take their love to another level this spring with a host of new ways to explore the city where the fictional hero lived, loved and trained.
The beloved character of Rocky Balboa has made yet another comeback this month with official debut of Rocky on Broadway in New York City on March 13 and the recent release of the Rocky Heavyweight Collection featuring all six Rocky films on DVD and Blu-Ray.
And now fans can enter to win The Ultimate Rocky Weekend Experience Sweepstakes presented by Visitphilly.com.
Through April 4, enter to win The Ultimate Rocky Weekend (to be redeemed August 7-9, 2014) including a one-night stay at the New York Marriott Marquis, a two-night stay at the Philadelphia Marriott Downtown, two tickets to Rocky on Broadway, two tickets to the Philadelphia Museum of Art, a tour of the Italian market, dinner at Victor Café and more.
The contest is open through April 4, but enter now for a chance at the prize. Full details are available at visitphilly.com/rocky.
Plus, to celebrate Rocky anytime, check out this Quintessential Rocky Tour of Philadelphia, a self-guided tour encompassing sites featured in many of the Rocky films, including the Philadelphia Museum Art, the Italian Market and Independence Hall.
And for even more Philadelphia Rocky-themed tours, attractions and sights, check right here.
Ultimate Rocky Weekend Sweepstakes [Visitphilly.com]
Rocky's Philadelphia [Visitphilly.com]
Tagged as:ArtsAttractionsBenjamin Franklin ParkwayContestsDealsEventsFairmountFilmFreeGiveawayIconic PhiladelphiaMovieMuseumsPhiladelphia Museum of ArtPhiladelphia NeighborhoodsRockyVisit Philly
I would love to come to Philadelphia My granddaughter goes to Bryn Mawr. Just turned 70 and want to climb the steps Thank you
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Although sources say many rockets were fired at Eilat FROM Jordan..
Israeli Defence Minister Shaul Mofaz speaking said the attacks were "intended to hit the Israeli side and the Jordanian side as well".
"We still don't know who is behind this act," he said, adding that the Israeli and Jordanian authorities were co-operating over the incident.
A Jordanian security source said authorities were searching for three men in the Katyusha missile attack, which was launched from an industrial warehouse area near the entrance to the city.
"We are searching for a Syrian and two Iraqis who are in Aqaba and used Kuwaiti number plates," the source said.


text:
Volume 44, Issue 03
Volume 44, Issue 03
Top Stories
Food-and-drink spots, deals, events and news
ANNIVERSARY SPECIAL: Tax cuts, privatization, sleaze, and the demise of California
ANNIVERSARY SPECIAL: The manipulations and media machine behind the assault on progressive ideas
ANNIVERSARY SPECIAL: The Golden State that invented the tax revolt is failing, but the conservative movement presses on
Volume 44, Issue 03
News & Culture
Volume 44, Issue 03
Food & Drink
Gemini life, and Fillmore Mexican Grill
Digging in to the streetwise beef of Urbun Burger and Mission Burger
Volume 44, Issue 03
Arts & Culture
Sleepwalkers' Zombie Town has brains (and eats them, too!)
Gossip do the right thing, major label or no. Plus: Budget Rock, Islands, and more
East Oakland's best kept secret finally gets a deal will he get the respect he deserves?
The devil and Daniel Johnston or, music touched with fire
Bronson's notorious subject inspires a star-making performance
Behold, Antichrist
Puffing past the queers vs. reggae debate. Plus: Kid Sister, The Very Best, and more
Despite a series of setbacks, Oakland Ballet returns -- again
Everything eats everything: a visit with prodigious primordial painter Henry Gunderson
Does the future of turntable DJing lie in the balance?


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Welcome to Australian International School Malaysia in Kuala Lumpur
Established since 2000, the Australian International School Malaysia is the only international school offering the Australian curriculum, right here in Kuala Lumpur. AISM has more than 670 students from 40 different nationalities, aged 3 to 18 years (pre-school to pre-university).
Highly qualified international teachers; predominantly Australian trained and experienced, are continually up-skilling their knowledge whilst encouraging students to explore, excel and extend their learning to their best potential, both in and out of the classroom. The school offers a holistic learning experience, leading to the Higher School Certificate (HSC) which is an internationally recognised qualification accepted by top universities around the world.
Whilst great emphasis is placed on academic excellence, the physical, emotional and social dimensions of growth are seen as crucial elements of our teaching and reflect the Australian education philosophy of developing the whole child.


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The Boot,unique cottage in Tasman,Nelson region NZ
From $247 / night
Description from the owner
Description from the owner
Bedrooms: 1/
Bathrooms: 1/
Sleeps: 2/
Type: Bed and Breakfast
The Boot is a unique luxury retreat offering peace and privacy for couples on holiday or for romantic weekends and special occasions. Located in the heart of the Ruby Coast ideally situated for exploring the Abel Tasman and Nelson region.
Nestled within a grove of hazelnut trees, The Boot opens onto a private courtyard surrounded by a fragrant garden. Relax on sunny afternoons and spend lazy evenings dining alfresco beside the outdoor fire. The perfect environment to unwind and enjoy each others company.
Inside, in the lounge there is a comfy couch for you to snuggle up on in front of the open fire.The kitchnette has complimentry tea, coffee and ...Read more
About the owner
About the owner
Judy Richards
Judy Richards
- Response rate: 58%
- Response time: Within a day
- Calendar updated: 2 months ago
Overall rating:
Additional Location Information
Our Location, Tasman Region
Located in the heart of the Ruby Coast in the beautiful Tasman region, you are only 30 minutes from the Able Tasman National Park, Kahurangi National Park and Nelson city.
The Boot is just minutes away from Kina Beach and Tasman Golf Course, with its magnificent views across the whole of Tasman Bay and the mountains all around. There are also a number of galleries and wineries, Mapua village and wharf are all within 10km.
From The Boot you are just a hop, skip and a jump, from the award winning Jester House cafe.
A perfect position for exploring the highlights of Tasman Bay, Nelson, New Zealand.


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Lofty celebration: McGhee Tyson Airport celebrates 75th anniversary
Editor's note: A previous version of this story incorrectly noted the airport's economic impact to the area.
James E. Anderson was just a little fellow on a warm July day when that American Airlines plane — a Stinson Trimotor — landed at McGhee Tyson Airport in Blount County, becoming the first of innumerable aircraft to do so.
Anderson, a Maryville resident, is 80 now and came to the airport Sunday to help it celebrate its 75th anniversary. With him were his son, Brian Anderson, and a great grandson, Brannon Beeson.
Tall and slim with bright white hair, Anderson was a 42-year employee of Capital Airlines, and he has some stories to tell about the aviation industry as it evolved from something fundamental and pretty freewheeling into the super complex, structured operation it is today.
Sunday afternoon's event brought a collection of airport officials and representatives of various local governments to the main concourse to voice support and congratulations for the airport. About 125 people attended the celebration, which included seven people portraying pioneers of the airport's history who interacted with visitors in what was billed as a "living wax museum."
In addition, a time capsule was loaded with letters and other items to be sealed and opened at the airport's centennial.
William F. Marrison, president of the Metropolitan Knoxville Airport Authority, told the crowd that the facility employs 2,500 people and than about 2 million passengers pass through it annually. It has, he said, a $600 million impact on the area's economy.
Howard H. Vogel, chairman of the MKAA board of commissioners, gave a brief history of the airport, noting that it was named for a World War I pilot who was lost over the North Sea. His family, in donating land for what is now Tyson Park, asked that the airport bear his name, Vogel said.
Also addressing the crowd were Knox County Mayor Tim Burchett, Eddie Mannis, representing Knoxville Mayor Madeline Rogero who was out of town, and U.S. Rep. John J. Duncan Jr., R- Knoxville.
Each placed a letter in the time capsule.
Other items placed inside were some 3-ounce plastic bottles signifying those prohibited by federal rule from being carried on planes, a BlackBerry phone, some baggage tags, a DVD of an employee flash mob celebrating the 75th anniversary, another DVD of some TV commercials, a hand-carved model rocking chair and items donated by the various departments at the airport.
Actors portrayed Lt. Col. Charles McGhee Tyson; Col. Harry S. Berry, who helped secure funding for the airport's construction in 1937; Walter Self, who helped found Knoxville Aero Corp.; Ferris and Ruth Thomas, who met and married as a result of their connections to the airport's early days; Tom Kesterson, who ran an early charter service at Downtown Island Airport, and Evelyn "Mama Bird" Bryan Johnson, who logged 57,635.4 hours as a pilot and flight instructor.
As for Anderson, he has his own little history to tell.
His weathered 1948 Capital flight schedule shows times and prices for flights nationwide. The price for air passage from Knoxville to Chattanooga was $4.95. To Baltimore was $27.35; to Birmingham was $14.05.
And the schedule also shows "layover" times at some airports as brief as one minute.
Anderson says that on some flights planes only taxied to a stop to allow a flight attendant to open a door, toss off a bag of mail and accept another on board. Sometimes, he said, the plane never actually came to a full stop.
Capital Airlines, he said, was bought by United Airlines in 1961.
Anderson worked as an all-purpose hand for the airline from customer service to fueling the planes.
In his career he worked at various airports, including in New York City, Knoxville, Chattanooga and Cleveland. It was at Newport News, Va., that his duties included periodically driving a car out onto the runway to shoo away the deer that grazed too close to the landing zone.
He tells of standing on the roof of a terminal with a phone wired into the radio system to guide planes in if the pilot asked for a "straight-in" landing and of calculating the cloud ceiling using a mathematical triangulation device based on an auto headlight that shown skyward.
At one airport he worked at, the janitor was authorized to turn on runway lights for a corporate plane that sometimes arrived at night, when no one was there but the cleaning crew.
Anderson has experienced the coming of the jet age like few others, and he was on hand Sunday to offer his flight schedule for the time capsule.
It was not accepted because the airport wanted current items for the encapsulation. But it may be archived for its historical value, airport officials said.
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Member Recognition
Association Events Calendar
November 2015
Zero Harm
With the advent of the new Health & Safety at Work legislation going active April 2016 it is probably timely to remind ourselves why we aim for a zero harm work environment.
This video has been reproduced courtesy of Danny Black. General Manager of Terex Australia
The 2015 Crane Safety Manual Ver 3 is now available from the New Zealand Crane Training Shop. See more here
Download video here for your own safety toolbox meetings
What the Association Does?
The Crane Association of New Zealand Inc is the national trade association for companies that operate or hire cranes and offer ancillary services relating to the crane industry.
The Association acts as a conduit between the members, the regulators and the training providers to provide leadership in crane industry best practice. It facilitates the highest standards of workplace safety, and promotes the premise that all crane operators must be trained, competent and are qualified on the equipment they are operating in the work environment.
To achieve this, the association works closely with its members, the government departments and agencies, Industry Training Organisation (ITO) as well as other associations and stakeholders.
Benefits of Membership
Financial Members of the Association receive the following benefits:
Services Our Members Offer
Our services include the following:
Joining the Association
If in your business you are using any of the following types of crane or supply the crane industry, then join the association and be recognised as a leader in the industry:
You can find out more about joining the association here.


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Hi, Im just wondering if you can use the drums mic and guitar for both these games and the mic for some of the new singing games lips, sing it and idol.
What is the better bundle to buy guitar hero or rock band????
Guitar Hero And Rock Band Are The Conrolls Compatable
Started by kandd , Nov 25 2008 08:44 AM
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Meadowdale's Ashley Aven is battling a terminal case of leukemia, but she refuses to give up and is inspiring others.
LYNNWOOD — The words cover less than a single page in a thin spiral notebook, but the handwritten ledger is part of what Ashley Aven lives for.
She calls it her to-do list.
Enjoy dad's lemon chicken dinner. Visit the zoo and aquarium. Walk with her graduating class at Meadowdale High School.
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Aven likes to look ahead, like a lot of 18-year-olds, but doesn't dare look too far. She has already defied the odds that doctors at Children's Hospital gave her on Jan. 2, when her parents were told she had two months to live.
"We're four months into this two-month nightmare," says her father, Bill Aven.
That nightmare started last July 8, when the Avens where hit with a three-word sucker punch: Acute myeloid leukemia.
Ashley, who would have been a senior at Meadowdale this year and a starting outfielder on the softball team, thought she had the flu or anemia last summer when her "whole body hurt" and a fever spiked to 104. She wound up at Children's Hospital, where she spent six months enduring three agonizing rounds of chemotherapy.
But her cancer levels never got low enough for a bone-marrow transplant, and her body couldn't withstand more full-fledged chemo.
Ashley Aven could have curled up in bed and given up. But she keeps swinging away, committed to carrying her fight into extra innings. She has become an inspiration to many, including the Meadowdale softball team she now helps coach.
Her mantra remains: "I'm not going anywhere."
For Aven, this isn't about denial, but determination to live life to the fullest.
"I've got stuff I want to do"
Go home, the doctors said. Live life. For eight weeks. Two months.
Ashley doesn't buy it.
"You know, Dad, I call bull on this two-month thing," she said during one of their many drives to the hospital from their Lynnwood home. "It's just not going to work out. I've got stuff I want to do."
She started her to-do list — don't you dare label it her bucket list — shortly after being sent home.
Graduation? Dale Cote, Meadowdale principal, has her honorary diploma — Ashley has been unable to attend any classes this school year — ready in his office any time she wants to pick it up.
Aven wasn't supposed to see her 18th birthday April 6. Yet she and the family — including 20-year-old sister Leticia — spent it in Palm Springs, Calif., visiting her grandmother. In February, they went to Disneyland courtesy of the Make-A-Wish Foundation.
Ashley plans to go to her senior prom and recently started talking about a Las Vegas trip in May.
"We'll see," Bill said.
"If I can fight, you can fight"
Ashley misses softball and her teammates. They refuse to let her go, drawing strength when she's around. The team presented the girl they call "Speedy," because of her quickness, with a letterman's jacket earlier this year. Players wear patches with her No. 2 on their jerseys, and she is listed on every lineup card.
The team struggled early, starting 1-6, but has won two out of three since Aven attended a practice.
"If I can fight, you can fight," she told them.
She has been the first-base coach in back-to-back wins.
"She's my inspiration," senior infielder Jade Lennstrom said.
More than once Aven has said, "Cancer doesn't have me, I have cancer."
She doesn't want to be treated any differently than before.
"The only thing is that I look different. I have short hair," said Aven, now with a half-inch, baby-soft do.
Losing her dark brown locks three times to chemo has been one of the toughest parts of this illness. The first time, continuous clumps of her shoulder-length hair on her pillowcase convinced her to let her nurses help her shave it off.
"I feel so free," she told her parents.
Soon after, Bill and her 14-year-old brother, Eric, shaved their heads, too.
"I'm not going anywhere"
Ashley rarely opens up about her illness and prognosis, and who can blame her?
"I don't really think about it that much," she insisted.
But she listens, absorbing it all. Ashley could barely keep her eyes open recently while her mom talked about the family's shattered finances. Their insurance had lapsed two days before Ashley was diagnosed as Bill had changed jobs.
When Tamara said she has money set aside for a funeral and memorial, Ashley snapped to attention.
"I'm not going anywhere," Ashley said.
"I know you're not," Tamara answered softly.
Tamara tries to be the pragmatist, the rock of the family.
"I had to tell Ashley that she's dying," she said.
That excruciating conversation came after a mid-January meeting Bill and Tamara had with doctors. As Ashley walked through the hospital cafeteria with her parents, she demanded to know what the doctors said.
"Let's talk about it when we get home," Tamara said.
"No, I want to know now," Ashley insisted.
The three found a table.
The message was grim. "There is no cure, Ashley, and you will die from this, and it's terminal, and we'll fight it and keep up the attitude," Tamara said.
Ashley began to cry.
"I want to go home now," she said finally, wiping away her tears.
It was quiet the whole way home.
The illness has drawn the family close. Ashley and Tamara sleep together — Bill, a round, loving man, snores too loud — and watch endless hours of TV, particularly on the Lifetime channel. Lots of "Law & Order" and "Grey's Anatomy." And "Ellen," always "Ellen," a favorite at the hospital.
A large banner signed by Meadowdale students hangs on the wall of her bedroom. Signs of support are everywhere, including several softballs signed by opposing teams. She has been asked to throw out the first pitch at the May 8 Washington softball game.
"Please don't let me die"
She is so brave, so focused on beating the odds, it's easy to forget how much emotion is locked inside her. She rarely lets it out.
When Bill teared up recently talking about the day doctors told him to take Ashley home, she quickly caressed his arm, grabbed his hand and put her head on his shoulder.
Even with mom, who battles fibromyalgia, Ashley rarely shares her feelings and fears. It's heart-wrenching when she does.
Tamara recalls one especially difficult day when Ashley revealed the depth of her despair.
"Mom, I don't want to die," she said. "Please don't let me die."
Bill copes in part by writing in an online journal he started soon after Ashley's diagnosis.
Bill frequently signs off with "BIG DEEP BREATH." That became his mantra after he stood outside Children's Hospital one day "having a moment." An old man saw him.
"Take a deep breath," the old man said.
Leticia, who lives nearby and visits regularly, doesn't like to talk about her kid sister's health. Eric, a freshman, sees a counselor at home and said he gets a lot of support at school, especially from his three best friends, who help him sell the colorful $2 support bracelets with Ashley's name on them and the phrase "Deep Breath."
Eric smiles a lot, but worries about his sister.
"Sometimes in math class, I just kind of sit there and stare at the intercom and I'm just thinking they're going to call me down to the office and tell me my sister passed away," he said.
Bill and Tamara worry, too. Ashley is more fatigued and body aches persist, signs the cancer may be growing again.
"I know she's getting worse," Tamara said.
Time is ticking, but Ashley doesn't believe even a doctor can predict life and death.
"They don't know when a person's going to die or not," she said. "I don't think anyone can say, 'You're going to die on this day,' or 'You're going to die in two days.' They don't know."
After all, Ashley Aven has stuff she wants to do. She isn't planning on going anywhere.
Sandy Ringer: 206-718-1512 or email@example.com


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KNOXVILLE, Tenn (WVLT) -- The Knoxville stars helped raise more than $87,000 for East Tennessee Children's Hospital. That's $30,000 more than last year!
Our own Lorena Estrada put her salsa shoes on and gave an incredible performance! She raised more than $5,000.
Her and her dancing partner, Chris Larsen, practiced for weeks.
Several Knoxville stars competed at the Knoxville Expo Center Thursday night.
With a perfect score of 30, Dixie Stampede's Jay Teter took home first place for his performance. Renita Stinnett with the Knoxville Expo Center raised the most money.
Special thanks to Papa Murphy's Take and Bake Pizza, Carleo's in the old City, Nick and J's Cafe on Lovell Road, and all her friends and family for their support in Lorena's fundraising!
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